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Azapirones are a class of drugs used as anxiolytics and antipsychotics.[1][2][3][4] They are commonly employed to augment antidepressants, such as selective serotonin reuptake inhibitors (SSRIs).[5][6][7][8][9]
List of azapirones[edit]
The azapirones include the following agents:[10]
- Anxiolytics
- Alnespirone (S-20,499)
- Binospirone (MDL-73,005)
- Buspirone (Buspar)
- Enilospirone (CERM-3,726)
- Eptapirone (F-11,440)
- Gepirone (Ariza, Variza)
- Ipsapirone (TVX-Q-7,821)
- Revospirone (BAY-VQ-7,813)
- Tandospirone (Sediel)
- Zalospirone (WY-47,846)
- Antipsychotics
- Perospirone (Lullan)
- Tiospirone (BMY-13,859)
- Umespirone (KC-9,172)
Tandospirone has also been used to augment antipsychotics in Japan as it improves cognitive and negative symptoms of schizophrenia.[11] Buspirone is being investigated for this purpose as well.[12][13]
Buspirone was originally classified as an azaspirodecanedione, shortened to azapirone or azaspirone due to the fact that its chemical structure contained this moiety, and other drugs with similar structures were labeled as such as well. However, despite all being called azapirones, not all of them actually contain the azapirodecanedione component, and most in fact do not or contain a variation of it. Additionally, many azapirones are also pyrimidinylpiperazines, though again this does not apply to them all.
Drugs classed as azapirones can be identified by their -spirone or -pirone suffix.[14]
On a pharmacological level, azapirones varyingly possess activity at the following receptors:[15][16][17][18][19][20][21][22]
- 5-HT1A receptor (as partial or full agonists)
- 5-HT2A receptor (as inverse agonists)
- D2 receptor (as antagonists or partial agonists)
- α1-adrenergic receptor (as antagonists)
- α2-adrenergic receptor (as antagonists)
Actions at D4, 5-HT2C, 5-HT7, and sigma receptors have also been shown for some azapirones.[23][24][25][26]
While some of the listed properties such as 5-HT2A and D2 blockade may be useful in certain indications such as in the treatment of schizophrenia (as with perospirone and tiospirone), all of them except 5-HT1A agonism are generally undesirable in anxiolytics and only contribute to side effects. As a result, further development has commenced to bring more selective of anxiolytic agents to the market. An example of this initiative is gepirone, which is currently in clinical trials in the United States for the treatment of major depression and generalized anxiety disorder. Another example is tandospirone which has been licensed in Japan for the treatment of anxiety and as an augmentation to antidepressants for depression.
5-HT1A receptor partial agonists have demonstrated efficacy against depression in rodent studies and human clinical trials.[27][28][29][30] Unfortunately, however, their efficacy is limited and they are only relatively mild antidepressants. Instead of being used as monotherapy treatments, they are more commonly employed as augmentations to serotonergic antidepressants like the SSRIs.[5][6][7][8][9] It has been proposed that high intrinsic activity at 5-HT1A postsynaptic receptors is necessary for maximal therapeutic benefits to come to prominence, and as a result, investigation has commenced in azapirones which act as 5-HT1A receptor full agonists such as alnespirone and eptapirone.[31][32][33][34] Indeed, in preclinical studies, eptapirone produces robust antidepressant effects which surpass those of even high doses of imipramine and paroxetine.[31][32][33][34]
Azapirones are poorly but nonetheless appreciably absorbed and have a rapid onset of action, but have only very short half-lives ranging from 1–3 hours. As a result, they must be administered 2-3 times a day. The only exception to this rule is umespirone, which has a very long duration with a single dose lasting as long as 23 hours.[35] Unfortunately, umespirone has not been commercialized. An extended release formulation of gepirone is currently under development and if approved, should help to improve this issue.
Metabolism of azapirones occurs in the liver and they are excreted in urine and feces. A common metabolite of several azapirones including buspirone, gepirone, ipsapirone, revospirone, and tandospirone is 1-(2-pyrimidinyl)piperazine (1-PP).[36][37][38] 1-PP possesses 5-HT1A partial agonist and α2-adrenergic antagonist actions and likely contributes overall mostly to side effects.[36][37][39]
Side effects[edit]
Side effects of azapirones may include dizziness, headaches, restlessness, nausea, and diarrhea.[4][40]
Azapirones have more tolerable adverse effects than many other available anxiolytics like the benzodiazepines. Unlike benzodiazepines, azapirones lack abuse potential and are not addictive, do not cause cognitive/memory impairment or sedation, and do not appear to induce appreciable tolerance or physical dependence. However, azapirones are considered less effective in controlling symptoms in comparison and also require several weeks for their therapeutic benefits to come to prominence.[citation needed]
- ^ Eison AS (June 1990). "Azapirones: history of development". Journal of Clinical Psychopharmacology 10 (3 Suppl): 2S–5S. PMID 1973936.
- ^ Cadieux RJ (May 1996). "Azapirones: an alternative to benzodiazepines for anxiety". American Family Physician 53 (7): 2349–53. PMID 8638511.
- ^ Chessick CA, Allen MH, Thase M, et al. (2006). "Azapirones for generalized anxiety disorder". In Chessick, Cheryl A. Cochrane Database of Systematic Reviews (Online) 3: CD006115. doi:10.1002/14651858.CD006115. PMID 16856115.
- ^ a b Feighner JP, Boyer WF (1989). "Serotonin-1A anxiolytics: an overview". Psychopathology. 22 Suppl 1: 21–6. PMID 2567039.
- ^ a b Van Ameringen M, Mancini C, Wilson C (July 1996). "Buspirone augmentation of selective serotonin reuptake inhibitors (SSRIs) in social phobia". Journal of Affective Disorders 39 (2): 115–21. doi:10.1016/0165-0327(96)00030-4. PMID 8827420.
- ^ a b Bouwer C, Stein DJ (April 1997). "Buspirone is an effective augmenting agent of serotonin selective re-uptake inhibitors in severe treatment-refractory depression". South African Medical Journal 87 (4 Suppl): 534–7, 540. PMID 9180827.
- ^ a b Dimitriou EC, Dimitriou CE (December 1998). "Buspirone augmentation of antidepressant therapy". Journal of Clinical Psychopharmacology 18 (6): 465–9. doi:10.1097/00004714-199812000-00009. PMID 9864079.
- ^ a b Appelberg BG, Syvälahti EK, Koskinen TE, Mehtonen OP, Muhonen TT, Naukkarinen HH (June 2001). "Patients with severe depression may benefit from buspirone augmentation of selective serotonin reuptake inhibitors: results from a placebo-controlled, randomized, double-blind, placebo wash-in study". The Journal of Clinical Psychiatry 62 (6): 448–52. doi:10.4088/JCP.v62n0608. PMID 11465522.
- ^ a b Yamada K, Yagi G, Kanba S (April 2003). "Clinical efficacy of tandospirone augmentation in patients with major depressive disorder: a randomized controlled trial". Psychiatry and Clinical Neurosciences 57 (2): 183–7. doi:10.1046/j.1440-1819.2003.01099.x. PMID 12667165.
- ^ "The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances: Alphabetical list of stems together with corresponding INNs".
- ^ Sumiyoshi T, Matsui M, Nohara S, et al. (October 2001). "Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment". The American Journal of Psychiatry 158 (10): 1722–5. doi:10.1176/appi.ajp.158.10.1722. PMID 11579010.
- ^ Sumiyoshi T, Park S, Jayathilake K, Roy A, Ertugrul A, Meltzer HY (September 2007). "Effect of buspirone, a serotonin1A partial agonist, on cognitive function in schizophrenia: a randomized, double-blind, placebo-controlled study". Schizophrenia Research 95 (1–3): 158–68. doi:10.1016/j.schres.2007.06.008. PMID 17628435.
- ^ Piskulić D, Olver JS, Maruff P, Norman TR (August 2009). "Treatment of cognitive dysfunction in chronic schizophrenia by augmentation of atypical antipsychotics with buspirone, a partial 5-HT(1A) receptor agonist". Human Psychopharmacology 24 (6): 437–46. doi:10.1002/hup.1046. PMID 19637398.
- ^ "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). 2004. Retrieved April 2010.
- ^ Hamik; Oksenberg, D; Fischette, C; Peroutka, SJ (1990). "Analysis of tandospirone (SM-3997) interactions with neurotransmitter receptor binding sites". Biological Psychiatry 28 (2): 99–109. doi:10.1016/0006-3223(90)90627-E. PMID 1974152.
- ^ Barnes NM, Costall B, Domeney AM, et al. (September 1991). "The effects of umespirone as a potential anxiolytic and antipsychotic agent". Pharmacology, Biochemistry, and Behavior 40 (1): 89–96. doi:10.1016/0091-3057(91)90326-W. PMID 1685786.
- ^ Ahlenius S, Wijkström A (November 1992). "Mixed agonist-antagonist properties of umespirone at neostriatal dopamine receptors in relation to its behavioral effects in the rat". European Journal of Pharmacology 222 (1): 69–74. doi:10.1016/0014-2999(92)90464-F. PMID 1361441.
- ^ Sumiyoshi T, Suzuki K, Sakamoto H, et al. (February 1995). "Atypicality of several antipsychotics on the basis of in vivo dopamine-D2 and serotonin-5HT2 receptor occupancy". Neuropsychopharmacology 12 (1): 57–64. doi:10.1016/0893-133X(94)00064-7. PMID 7766287.
- ^ Weiner DM, Burstein ES, Nash N, et al. (October 2001). "5-hydroxytryptamine2A receptor inverse agonists as antipsychotics". The Journal of Pharmacology and Experimental Therapeutics 299 (1): 268–76. PMID 11561089.
- ^ Hirose A, Kato T, Ohno Y, et al. (July 1990). "Pharmacological actions of SM-9018, a new neuroleptic drug with both potent 5-hydroxytryptamine2 and dopamine2 antagonistic actions". Japanese Journal of Pharmacology 53 (3): 321–9. doi:10.1254/jjp.53.321. PMID 1975278.
- ^ Kato T, Hirose A, Ohno Y, Shimizu H, Tanaka H, Nakamura M (December 1990). "Binding profile of SM-9018, a novel antipsychotic candidate". Japanese Journal of Pharmacology 54 (4): 478–81. doi:10.1254/jjp.54.478. PMID 1982326.
- ^ Odagaki Y, Toyoshima R (2007). "5-HT1A receptor agonist properties of antipsychotics determined by [35S]GTPgammaS binding in rat hippocampal membranes". Clinical and Experimental Pharmacology & Physiology 34 (5–6): 462–6. doi:10.1111/j.1440-1681.2007.04595.x. PMID 17439416.
- ^ Roth BL, Tandra S, Burgess LH, Sibley DR, Meltzer HY (August 1995). "D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs". Psychopharmacology 120 (3): 365–8. doi:10.1007/BF02311185. PMID 8524985.
- ^ Herrick-Davis K, Grinde E, Teitler M (October 2000). "Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors". The Journal of Pharmacology and Experimental Therapeutics 295 (1): 226–32. PMID 10991983.
- ^ Rauly-Lestienne I, Boutet-Robinet E, Ailhaud MC, Newman-Tancredi A, Cussac D (October 2007). "Differential profile of typical, atypical and third generation antipsychotics at human 5-HT7a receptors coupled to adenylyl cyclase: detection of agonist and inverse agonist properties". Naunyn-Schmiedeberg's Archives of Pharmacology 376 (1–2): 93–105. doi:10.1007/s00210-007-0182-6. PMID 17786406.
- ^ Itzhak Y, Ruhland M, Krähling H (February 1990). "Binding of umespirone to the sigma receptor: evidence for multiple affinity states". Neuropharmacology 29 (2): 181–4. doi:10.1016/0028-3908(90)90058-Y. PMID 1970425.
- ^ Kennett GA, Dourish CT, Curzon G (February 1987). "Antidepressant-like action of 5-HT1A agonists and conventional antidepressants in an animal model of depression". European Journal of Pharmacology 134 (3): 265–74. doi:10.1016/0014-2999(87)90357-8. PMID 2883013.
- ^ Blier P, Ward NM (February 2003). "Is there a role for 5-HT1A agonists in the treatment of depression?". Biological Psychiatry 53 (3): 193–203. doi:10.1016/S0006-3223(02)01643-8. PMID 12559651.
- ^ Robinson DS, Rickels K, Feighner J, et al. (June 1990). "Clinical effects of the 5-HT1A partial agonists in depression: a composite analysis of buspirone in the treatment of depression". Journal of Clinical Psychopharmacology 10 (3 Suppl): 67S–76S. PMID 2198303.
- ^ Bielski RJ, Cunningham L, Horrigan JP, Londborg PD, Smith WT, Weiss K (April 2008). "Gepirone extended-release in the treatment of adult outpatients with major depressive disorder: a double-blind, randomized, placebo-controlled, parallel-group study". The Journal of Clinical Psychiatry 69 (4): 571–7. PMID 18373383.
- ^ a b Koek W, Patoiseau JF, Assié MB, et al. (October 1998). "F 11440, a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential". The Journal of Pharmacology and Experimental Therapeutics 287 (1): 266–83. PMID 9765347.
- ^ a b Koek W, Vacher B, Cosi C, et al. (May 2001). "5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential". European Journal of Pharmacology 420 (2–3): 103–12. doi:10.1016/S0014-2999(01)01011-1. PMID 11408031.
- ^ a b Prinssen EP, Colpaert FC, Koek W (October 2002). "5-HT1A receptor activation and anti-cataleptic effects: high-efficacy agonists maximally inhibit haloperidol-induced catalepsy". European Journal of Pharmacology 453 (2–3): 217–21. doi:10.1016/S0014-2999(02)02430-5. PMID 12398907.
- ^ a b Maurel JL, Autin JM, Funes P, Newman-Tancredi A, Colpaert F, Vacher B (October 2007). "High-efficacy 5-HT1A agonists for antidepressant treatment: a renewed opportunity". Journal of Medicinal Chemistry 50 (20): 5024–33. doi:10.1021/jm070714l. PMID 17803293.
- ^ Holland RL, Wesnes K, Dietrich B (1994). "Single dose human pharmacology of umespirone". European Journal of Clinical Pharmacology 46 (5): 461–8. PMID 7957544.
- ^ a b Manahan-Vaughan D, Anwyl R, Rowan MJ (December 1995). "The azapirone metabolite 1-(2-pyrimidinyl)piperazine depresses excitatory synaptic transmission in the hippocampus of the alert rat via 5-HT1A receptors". European Journal of Pharmacology 294 (2–3): 617–24. doi:10.1016/0014-2999(95)00605-2. PMID 8750726.
- ^ a b Blier P, Curet O, Chaput Y, de Montigny C (July 1991). "Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine--II. Effects of acute administration of 1-PP and long-term administration of tandospirone on noradrenergic neurotransmission". Neuropharmacology 30 (7): 691–701. doi:10.1016/0028-3908(91)90176-C. PMID 1681447.
- ^ Löscher W, Witte U, Fredow G, Traber J, Glaser T (September 1990). "The behavioural responses to 8-OH-DPAT, ipsapirone and the novel 5-HT1A receptor agonist Bay Vq 7813 in the pig". Naunyn-Schmiedeberg's Archives of Pharmacology 342 (3): 271–7. PMID 2149168.
- ^ Zuideveld KP, Rusiç-Pavletiç J, Maas HJ, Peletier LA, Van der Graaf PH, Danhof M (December 2002). "Pharmacokinetic-pharmacodynamic modeling of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in rats". The Journal of Pharmacology and Experimental Therapeutics 303 (3): 1130–7. doi:10.1124/jpet.102.036798. PMID 12438536.
- ^ Newton RE, Marunycz JD, Alderdice MT, Napoliello MJ (March 1986). "Review of the side-effect profile of buspirone". The American Journal of Medicine 80 (3B): 17–21. doi:10.1016/0002-9343(86)90327-X. PMID 2870641.


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is there a free web page editor program available for download?
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is there a free web page editor program available for download?I'm creating a website. I was interested in a free web page editor program if anyone knows of any that I can download. I have Micro-Publisher. It's ok, it gets the job done, but it isn't so USER FRIENDLY. Any ideas?
Asked By: VWest - 11/2/2010
Best Answer - Chosen by Asker
You've got a lot of choices open to you as to what to use as an editor. Something very basic such as Notepad, something a little more specialized such as Notepad++ (free) - http://notepad-plus-plus.org/ - or EditPlus (pay) - http://www.editplus.com/ or VEdit (pay) - http://www.vedit.com/ - up to all singing, all...
Answered By: brisray - 11/2/2010
Additional Answers (2)
I would try the programs on this list and use the one you like:
For future reference, the kind of editor you are wanting to use is called a WYSIWYG editor. Aka. "What you see is what you get."
Answered By: ThatGuyCharlie - 11/2/2010
Err old-school Notepad.
Answered By: Curt Bleach - 11/2/2010
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My FRED
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The loans provided through the TALF (refer to the note accompanying loans extended under the Term Asset-Backed Securities Loan Facility in table 1) to eligible borrowers are non-recourse, meaning that the obligation of the borrower can be discharged by surrendering the collateral to the FRBNY. TALF LLC is a limited liability company formed to purchase and manage any asset-backed securities received by the FRBNY in connection with the decision of a borrower not to repay a TALF loan. This line reports the fair value of the asset-backed securities and other investments held by the LLC. Because the FRBNY is the primary beneficiary of the LLC, the assets and liabilities of the LLC are consolidated onto the books of the FRBNY. |


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LIVE "ELF/ULF" MONITORING OF EARTHQUAKE PRECURSOR SIGNALS ON GLP. QUAKE FORECAST UP TO 6HRS IN ADVANCE...(((Updated Daily))) By ELQ.
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[quote:Luisport:MV8xNDk0NTg4XzM1MDEyNDA0XzhBQUUyRUEz] Anxieties rise as surge of tremors makes Navidad the shakiest town in Chile Posted on December 13, 2012 December 13, 2012 – NAVIDAD, Chile — One jolt hit in the middle of the night. Another caught fishermen at a nearby beach. Then the ground shook at supper. And then again, and again: More than 170 tremors were felt in Navidad in just five weeks. The strongest struck during a funeral, and sent panicked mourners fleeing into the street. Navidad, a coastal farming town of 5,500 people, has become one of the shakiest spots in one of the world's shakiest countries. And seismologists can't say whether these were aftershocks from Chile's devastating quake two years ago, or warnings of another huge disaster to come. Navidenos, though, have learned to take quakes in stride. In this town whose name means Christmas, some decorate Christmas trees with quakes in mind, wiring ornaments to the branches or taking extra efforts to secure the base. Restaurant owners nail wood railings panels to their shelves to keep glasses and liquor from crashing down. Some now use canned beer, shunning bottles as too risky. Children at public schools practice drills every day and everyone seems to have a quake bag with flashlights and food ready. "We were born, grew up and were raised with earthquakes," acting Mayor Rodrigo Soto said. "It seems like the world for the first time has discovered Navidad. Everyone asks us if we're scared and all we can say is that we need to be prepared." Still, no amount of preparation can avoid that panicky feeling when the ground really rumbles. There's no way to know at that moment whether the shaking will pass quickly, or become frighteningly worse. While the ground shook under the pews at the funeral, the faces of the mourners turned pale like the dead. Despite appeals for calm, the church swayed so much that people panicked and ran outside. "People were terrorized," Carolina Jeria, recalling that 5.9-magnitude quake on Nov. 21. "In a moment like that, you lose control. We're very worried about the quakes because the big one in 2010 caught us unprepared." Soto says the town still has an inadequate tsunami alert system — a siren that sounds like a car alarm and lacks the volume needed to reach all the townspeople. But after so many tremors, he says Navidenos know in their bones when to run. They know they'll barely feel a magnitude-2, but a magnitude-7 will knock them off their feet and that's a sign to scramble for high ground in case there's a tsunami. Aside from the quakes, life is slow in Navidad. Many farmers still use oxen to plow their land, while others cater to tourists who come for the Pacific beaches from Chile's capital of Santiago, 170 kilometers (100 miles) northeast of town. Yet people are often on edge. –AP/WP http://theextinctionprotocol.wordpress.com/ [/quote]
Original Message
I will be posting the signals I see on ELF here. I will post with intensity of each signal seen on the ELF range. I will post intensity using the Seismic scale from 1 to 10 Magnitudes. Be aware that once the signal comes in on ELF it can take from 1 hour and 40 minutes to 2 hours and 30 minutes for the quake to be seen on USGS sites. These signals come in on ELF about 1 1/2 to 2 hours before they actually impact what ever region their epicenters are. Then it takes USGS sites about 30 minutes to display.
The signals I pay attention to are in the 1 Hz to 10 Hz frequencies. Those are almost always Seismic.
I will be doing this when I am in front of my computer, not all the time so be aware that I will not be able to catch them all.
These ELF signals give approximately a 2 hour window to work and figure out epicenter. That is another task I will take on in the future. It is the hardest part of Earthquake prediction.
This is an addition I added to a thread about Elenin;
Be weary next 3 hours, have plan prepared for some possible shaking. Getting some unusual readings on ELF. Not sure if it will impact Japan region but better to be safe than sorry. Keep your mind focused and aware that Japan might be getting some seismic activity headed that way. This one might be 5+ if I am not mistaken. No panic just keep your senses on alert status.
The unusual activity I heard were 18 very intense thumps. In the 1Hz to 10Hz frequency. Could be seismic.
Then these quakes occurred;
Wednesday May 18 2011, 19:37:52 UTC 25 minutes ago San Francisco Bay area, California 1.5 0.0 Detail
Wednesday May 18 2011, 19:26:21 UTC 37 minutes ago Fox Islands, Aleutian Islands, Alaska 2.2 3.1 Detail
Wednesday May 18 2011, 19:18:35 UTC 45 minutes ago Nevada 3.5 3.3 Detail
Wednesday May 18 2011, 19:09:28 UTC 54 minutes ago Central California 1.6 0.8 Detail
Wednesday May 18 2011, 19:01:40 UTC 62 minutes ago Southern Alaska 1.6 45.3 Detail
Wednesday May 18 2011, 18:51:27 UTC 72 minutes ago eastern New Guinea region, Papua New Guinea 5.6 54.5 Detail
Wednesday May 18 2011, 18:43:15 UTC 80 minutes ago Nevada 1.3 5.3 Detail
Wednesday May 18 2011, 18:32:00 UTC 91 minutes ago Channel Islands region, California 2.3 1.8 Detail
Wednesday May 18 2011, 18:32:00 UTC 91 minutes ago Channel Islands region, California 2.3 1.8 Detail
Wednesday May 18 2011, 18:29:02 UTC 94 minutes ago eastern New Guinea region, Papua New Guinea 4.9 53.8 Detail
Wednesday May 18 2011, 17:43:43 UTC 2 hours ago Central California 2.9 7.5 Detail
Wednesday May 18 2011, 17:42:36 UTC 2 hours ago off the east coast of the Kamchatka Peninsula, Russia 5.6 18.2 Detail
Wednesday May 18 2011, 17:39:41 UTC 2 hours ago Strait of Juan de Fuca, Washington 1.1 1.9 Detail
Wednesday May 18 2011, 17:15:57 UTC 2 hours ago off the east coast of Honshu, Japan 5.0 46.1 Detail
link to quakes.globalincidentmap.com
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Managed in cooperation withSouthwest Florida Water Management District
Iris in forest
The 4,155 acres of Potts WMA protect the water resources along the Withlacoochee River and the Tsala Apopka Chain of lakes in northeast Citrus County. Natural areas include floodplain forests along the Withlacoochee River, freshwater marshes, and scrub oak communities, which support a small population of the threatened Florida scrub-jay. Through a process called succession, old pastures are returning to natural communities such as pine flatwoods, which are vital to Florida's native wildlife. Hunting, fishing, wildlife viewing, and frogging are some of the recreational opportunities available on the area. You can hike on nearly 30 miles of paths, with two loop trails. Swamp lilies and blue flag irises bloom along the river trail in the spring. Biking is available on roads. Camping is permitted at five primitive campsites. Horseback riding is available on 12 miles of marked woods trails, where white-tailed deer, gopher tortoise, and wild turkey may be observed. Children under the age of 16 are required to wear a helmet when horseback riding on public lands. For more detailed information go to Nicole's Law . All horseback riders must have proof of current negative Coggins Test results for their horses when on state lands. Paddling is permitted in the creeks and marshes but you need a permit from the Southwest Florida Water Management District to use a vehicle to transport your boat to the closest water entry. This area is a site on the Great Florida Birding Trail.
Rules Regarding Dogs
Visit Southwest Florida Water Management District's Recreation Guide for Potts.
View FWC's Regulations Summary for Potts for an area map, hunting seasons, permits, fees, and area regulations.
FWC Facts:Black bears originated in North America, and have been here at least 1.5 million years.
Learn More at AskFWC


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Washington State Department of Revenue – Tumwater, WA
Please review the opportunity details below or forward this message to interested candidates. Positions: Excise Tax Examiner 2 (in-training… CareerBuilder
2 people found this helpful
Pros: "The work load was pretty light, but my lead was great (so he usually made sure I had challenging, interesting projects). Flexible work hours were really nice for only coming in 4 days out of a week. The managers were all really nice." – Full Review
If you're searching for Washington Department of Revenue jobs and careers — we can help! Here you'll not only find the latest Washington Department of Revenue job openings, you can also see what Washington Department of Revenue employees have to say about a career at Washington Department of Revenue – salaries, reviews, and interview questions all posted anonymously by Washington Department of Revenue employees and job seekers.
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by The 401k Study Group in Business
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Join me today as I chat with James Holland from MillenniuM Investment & Retirement Advisors, LLC as we discuss the chaning landscape in the qualified plan space.
We will also touch on the "team" approach to qualified plans versus going it alone and the opportunites that present themselves when you stay in front of the CFO and Human Resource Directors.
The Alphabet Soup of the 401k Industry
by The 401k Study Group in Business
Tags: 401k The 401k Study Group Fiduciary Qualified Plans Unified Trust
Please tune in to listen to Jason Grantz, QPA, QKA, AIF and I discuss the myriad of numbers and letters that Plan Sponsors have to decipher. Advisors in the Qualified Plan should listen in to learn how Unified Trust can assist you and your Plan Sponsors with the process of choosing a 401k Provider.
Fidelity Bonding | Get Up to Date
by The 401k Study Group in Business
Tags: The 401k Study Group 401k NAPLIA Fidelity Bonding Plan Sponsor
Please join me today as Paul Smith Vice President and Gary Sutherland CEO from NAPLIA discuss the basics of fidelity bonds for 401k plans. As well as bonding issues for 3(38) Advisors; 3(16) Administrators; Plan Sponsors (stand alone) and Plan Sponsors (that are part of a MEP).
The topic will help Advisors understand the basics but will also be helpful for Plan Sponors to learn about their responsibilities.
Growing Your Business with T3 Direct
by The 401k Study Group in Business
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Join me as I chat with Kris Gaskins from T3 Direct as we chat about growing your 401k practice.
We will discuss how their services differ from their competitors in the field.
Ch-Ch-Changes in Advisor Fees & Services
by The 401k Study Group in Finance
Tags: Pulse Logic Ken Cochrane Advisor Fees The 401k Study Group
Join me as I discuss the changes in Advisor fees and service offerings over the last 18 months with Ken Cochrane.
Ken is the Managing Director of Pulse Logic, a Sponsor of The 401k Study Group and the creator of The Pulse Logic fee/service portal available to Advisors.
Professor Messer's Live A+ Study Group - October 2013
by Professor Messer in Technology
Tags: comptia A Plus study certification group
Join me for our live call-in study session!
Cash Flow Planning in the USA
by The 401k Study Group in Business
Tags: Cash Flow Financial Planning The 401k Study Group Stephanie Holmes-Winton Insurance
Join me as I interview Stephanie Holmes-Winton.
Stephanie is a Financial Services Speaker & Trainer with an expertise in Cash Flow Management. She has been in the Industry since 2001. During that time she found that there was a gaping hole in the financial plan where cash flow advice belonged. Since early in my career she's worked hard to fill that gap. In 2011 she sold her investment and insurance practice to focus her efforts on: "Being the change, we need in the Financial Services Industry" she would like to see Cash Flow Planning be a normal & standardized part of the financial planning process.
Al-Iman Prayer Group
by AlXIman Prayer Group sermon 1 in Islam
Tags: Sermon prayer Iman Group Islam Dua
Al- Iman Prayer group is an Islamic educative program that teaches both adult and children the light of Islam, it educates members on the true religion of islam, the teachings of Prophet Muhammed (SAW), Holy Quran and Hadith.
She Said What?! How to excel at Your Marketing
by The 401k Study Group in Business
Tags: April Rudin Marketing Branding Financal Advisor The 401k Study Group
Join me and April Rudin, President of The Rudin Group as we discuss what the right way is to market your practice to High Net Worth Clients.
April is a regular contributor to the Huffington Post, and speaks regularly and internationally on a wide range of branding topics client acquisition, social media and other topics for Financial Advisors.
Stressed About Your 401K?
by Guide to Financial Peace in Finance
Tags: 401k alternative investments retirement planning financial planning saving for retirement
If you are stressed about your 401k, You are not alone as a recent survey indicates 52% of Americans do not understand their 401k plan.
Why is the 401k so confusing?
What can you do to better understand your options?
Does it ever make sense to Not participate?
No BS Money Todd Strobel asks these questions and more as he interviews Best Selling Financial Author, Kim Butler.
More Info on Busting Retirement Planning Lies
Al-Iman Prayer Group
by AlXIman Prayer Group sermon 1 in Islam
Tags: Sermon prayer Iman Group Islam Dua
Al- Iman Prayer group is an Islamic educative program that teaches both adult and children the light of Islam, it educates members on the true religion of islam, the teachings of Prophet Muhammed (SAW), Holy Quran and Hadith.
Bible Prophecy Study Group
by In Christ Alone Ministries in Religion
Tags: rapture end-times Jesus bible prophecy
Join us this evening for our Bible Prophecy Study Group blogtalkradio program. We're on at 7pm eastern, 4pm pacific, 2pm Honolulu and midnight London every Friday with your hosts Jenny Perez-Monto and Missy C. Haynes at: Tonight's topic is: As usual, we will kick off the program with current news as it pertains to bible prophecy in the first hour followed by the bible prophecy study in the second hour. You can also reach us on FB at: http://www.facebook.com/groups/bibleprophecystudygroup/ We have an adjunct bible study group for bible prophecy at: https://www.facebook.com/groups/bibleprophecy2/ You can also find our studies and links to our radio show at: http://doeschristknowme.org/ Please follow us on our radio programs at 7pm eastern at: http://my.blogtalkradio.com/doeschristknowme Just click on "follow" under the icon of our ministry and you will get the link for every show. If you wish to participate in the chat room, we encourage you to obtain a free blogtalkradio account! Hope you join us! God blessings upon you and your loved ones!
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All of the First Steps therapists come to the Smiths' home to work with Roy. Over time the women have become almost like part of the family.JASON CLARK / COURIER & PRESS
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Build a Home for Life for Rescued Animals
Help give a Home for Life to special-needs animals.
Home For Life®, on the Apple River near Star Prairie, Wisconsin, is a different kind of animal shelter -- a place where animals that are considered unadoptable can live out their days in safety and comfort. Several hundred very lucky animals enjoy loving care in the Home For Life® facility, which includes indoor / outdoor enclosures for both dogs and cats, including a separate enclosure for cats with feline leukemia; a grooming station; apartments for pairs of animals that cannot tolerate large groups; and more.
With so many animals routinely put down in the United States each year, the need is far greater than the shelter's current capacity. Home For Life® needs help acquiring an adjoining parcel of land so that it can expand and save more animals in need. The land would serve as a buffer for the shelter, while allowing them to expand and care for more animals. In addition, much of the land is in its natural state -- native prairie, oak savanna, river frontage, and wetland habitats -- that will be preserved as "the other home for life" for several native protected species.
You can help. Your donation through this Gift That Gives More™ funds 208 square feet of land to expand the capacity of the Home For Life® animal shelter in Star Prairie, Wisconsin.
Home For Life® is a sanctuary that provides lifetime care for cats and dogs with special needs who cannot otherwise find homes, but who can still lead quality lives. These animals, including retired service dogs, come from across the U.S., from Canada, South Korea, Taiwan, and from many U.S. shelters that cannot find homes for them. In addition, Home for Life® trains many of its animals to give back as certified pet therapists through Pet Peace Corps, which serves hospital and hospice patients, families healing from domestic abuse, and at-risk youth.
Free Standard Shipping in the U.S. on your entire cart when you donate $15.00 or more in our Gift That Gives More™ program. See Current Promotions for details.
Why a Gift That Gives More™ is a smart, effective donation.
100% of your donation will go to the program described above as a grant through GreaterGood.org. GreaterGood stores do not receive any profit from donations through this Gift That Gives More™; we bring it to you in the spirit of the greater good. We even pay the credit card transaction fee, so every cent of your donation goes to charity.
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With a stay at Mercure Napoli Centro Angioino in Naples (Historical Center), you'll be minutes from Naples Town Hall and Castel Nuovo. This 4-star hotel is within close proximity of Expo Convention Centre and Piazza Matteotti. Read More About Mercure Napoli Centro Angioino
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Digital Streaming Media Devices
TiVo TCDA94000 Stream Digital Video Recorder
Stream and transfer shows to your mobile devices with TiVo Stream. Enjoy your favorite shows in the kitchen, on the stairs, or on the back porch. Stream up to four shows at once to four devices connected to your home network. Want to move your content to planes, trains and automobiles? No problem. Wirelessly transfer recorded content to your mobile device and hit the road. All you need is a...
TiVo TCD649080 Series 2 80-Hour Dual Tuner Digital Video Recorder
The world's first, best, and easiest-to-use digital video recorder just got better. Now, record two shows at once. Only the TiVo service gives you the freedom to watch your favorite shows any time, anywhere.
Apple MA711LL/A TV with 40GB Hard Drive
The digital revolution continues, and you don't want to be without your best weapon! Apple TV lets you bring material you've downloaded to your PC or Mac, and transport it directly to your TV screen! Instead of constricted to your computer monitor, your can plop down on your couch, get your drinks and snacks, and turn up the action!
Mediabrowser 3
Media Browser, beginning with version 3, is no longer a single program. It encompasses a large suite of applications all communicating with a central server that manages your library. No longer locked inside Windows Media Center, Media Browser can now bring your entire media library to not only all of the computers on your network, but also many of your portable devices. Whether it's...
Popcorn Hour A-300 Networked Media Jukebox
Mesmerize your audience with a lightning fast media jukebox experience and seamless navigation using a liquid smooth Adobe Flash based user interface. The A-300 accelerates your digital life with the following enhancements: All new Sigma Designs 8647 800MHz CPU with L2 Cache, new and improved Networked Media Jukebox V2, USB 3.0 connection to your PC and Gigabit Ethernet for flawless streaming...
Seagate FreeAgent Theater+1080P HD Media Player STCEA201-RK
The FreeAgent Theater+ HD media player provides an easy way to store and move your photos, movies and music from your PC or Mac computer to your TV, allowing you to share and enjoy your digital media in a comfortable, social environment such as your living room. From your home computer, use the included sync software to automatically copy all of your media files to the FreeAgent Go drive, or...
Roku 2 HD Streaming Player
The best value in high-definition streaming to your TV with more than 300 channels of movies, TV shows, live sports, and more. Enjoy Netflix, Hulu Plus, Amazon Instant Video, Crackle, Pandora, and much more. Includes built-in wireless, and works with virtually any TV.Video Interface: (1) Composite RCA Video Port; (1) HDMI Port;Audio Interface (1) Composite RCA Audio Ports; (1) HDMI Port,Ports...
Toshiba DVR620 DVD Recorder/VCR Combo
You can have both VCR and DVD recording and playback capibilities without the clutter. This Toshiba DVR620 DVD Recorder/VCR Combo takes the fuss out of saving your videotapes to DVD. It also enhances DVD picture quality to near HD with 1080p upconversion via HDMI™.
Sony FMP-X1 4K Ultra HD Media Player
"It has been a simple and effective source of program material. Only issues are that we would like more new program material, and from the time you push the button to purchase or rent something that is not pre-sent, there is a long delay of at least hours. The device automatically will load new material so that it can be purchased with zero delay. Delay is not issue for me. I'm not in that big a..." --bobnorth65


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Organic Chocolate Covered Sensations
Dreamily delectable, these yummy morsels covered in rich dark chocolate are the perfect way to reward yourself for a good day's work -- or to indulge someone you're sweet on. Better yet, your purchase of these delights helps the Candela Peru organization to support ecologically sustainable economic growth along the Amazon River (click below for more information).
- Brazil Nut, Coffee Bean, or Goldenberry
- Certified organic
- 2 oz
- Made in and fairly traded from Peru
Shop Green!
Please note this item is not available for express shipping. Adding this item to your cart will prevent your order from displaying express shipping options.
Chocolate-Covered Brazil Nuts: Organic Brazil Nut pieces (42%), organic sugar, organic cocoa liquor, organic cocoa butter, organic (non GMO) soy lecithin, organic gum arabica.
Chocolate-Covered Coffee Beans: Organic Coffee (10%), organic sugar, organic cocoa liquor, organic cocoa liquor, organic cocoa butter, organic (non GMO) soy lecithin, organic gum arabica.
Chocolate-Covered Golden Berries: Organic dried goldenberry (35%), organic sugar, organic cocoa liquor, organic cocoa butter, organic (non GMO) soy lecithin, organic gum arabica.
*All varieties may contain traces of nuts*This item ships from a third party and may be excluded from certain promotions. Please see the Current Promotions page for details.
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Coordinates: 51°21′50″N 1°02′46″E / 51.364°N 1.046°E
Tankerton | |
Tankerton beach on the borders of Swalecliffe |
Tankerton shown within Kent |
Population | 4,900 (2005)[1] |
OS grid reference | TR120669 |
District | City of Canterbury |
Shire county | Kent |
Region | South East |
Country | England |
Sovereign state | United Kingdom |
Post town | Whitstable |
Postcode district | CT5 |
Dialling code | 01227 |
Police | Kent |
Fire | Kent |
Ambulance | South East Coast |
EU Parliament | South East England |
UK Parliament | Canterbury |
Tankerton (formerly Tankerton-on-Sea) is a suburb of Whitstable in south-east England. It was designed in the late 19th century as the train network brought holidaymakers to the sea.
Tankerton-on-Sea was a commercial development by the Tankerton Estate Company in the late 19th century, and was designed with a grid of streets leading from the shoreline.
The slopes to the shore are a site of special scientific interest (SSSI) because they support the largest single population of the large umbellifer hog's fennel Peucedanum officinale in Britain.[2]
The economy is based around tourism. The little wooden beach huts at the base of the slopes are currently highly desirable, and notable owners have included Tracey Emin, who sold hers to Charles Saatchi for £75,000.[3] Seaview Caravan Holiday Park adjoins Tankerton, and formerly also contained a large number of chalets, as well as static caravans and camping. It is one of the largest holiday parks on the North Kent coast
As of the 2001 UK census, the Tankerton electoral ward had a population of 4583. The ethnicity was 98.7% white, 0.4% mixed race, 0.6% Asian, 0.2% black and 0.1% other. The place of birth of residents was 95.3% United Kingdom, 0.7% Republic of Ireland, 1.3% other Western European countries, and 2.7% elsewhere. Religion was recorded as 80.2% Christian, 0.4% Buddhist, 0% Hindu, 0.1% Sikh and 0.2% Muslim. 12% were recorded as having no religion, 0.4% had an alternative religion and 6.6% did not state their religion.[4]
The economic activity of residents aged 16–74 was 34.3% in full-time employment, 12.6% in part-time employment, 11.3% self-employed, 1.9% unemployed, 2.2% students with jobs, 3.2% students without jobs, 22.3% retired, 5.8% looking after home or family, 4% permanently sick or disabled and 2.4% economically inactive for other reasons. The industry of employment of residents was 17% retail, 10.9% manufacturing, 8.2% construction, 9.9% real estate, 13% health and social work, 13.2% education, 6.9% transport and communications, 5.9% public administration, 4.2% hotels and restaurants, 4% finance, 1.2% agriculture and 5.6% other. Of the ward's residents aged 16–74, 20.6% had a higher education qualification or the equivalent, compared with 19.9% nationwide.[4]
See also[edit]
- ^ "2005 Ward Level Population Estimates". Kent County Council. September 2006. Retrieved 2007-08-20.
- ^ "Natural England - SSSIs : Introduction". English-nature.org.uk. Retrieved 2012-03-18.
- ^ [1][dead link]
- ^ a b "Neighbourhood Statistics". Statistics.gov.uk. Retrieved 2008-02-21.
External links[edit]
Wikimedia Commons has media related to Tankerton. |


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8273 Brittany Pl, Pittsburgh, PA 15237
Sold on 6/10/13: $295,000
Zestimate®: $301,267 A Zestimate® home valuation is Zillow's estimated market value. It is not an appraisal. Use it as a starting point to determine a home's value. Learn more
If your home facts are wrong this will cause an incorrect Zestimate, click here to update them.
A Zestimate® home valuation is Zillow's estimated market value. It is not an appraisal. Use it as a starting point to determine a home's value. Learn more
If your home facts are wrong this will cause an incorrect Zestimate, click here to update them.
Est. Mortgage:
- Bedrooms:5 beds
- Bathrooms:3 baths
- Single Family:3,040 sq ft
- Lot:0.41 acres
- Year Built:1965
- Last Sold:Jun 2013 for $295,000
- Heating Type:Contact for details
Inside and out, this is a beautifully finished home that has been lovingly cared for over the years. The open entry is large enough to welcome many guests into your home with a gorgeous accent of terrazzo tile that is not seen in every home. The family room and living room are both a very generous size and they each have a fireplace. The family room has built-in bookshelves and was recently painted. The formal dining room and kitchen were also painted neutral colors. The kitchen has custom cabinets, with updated hardware, a butcher block counter, a built in cutting board, and double ovens that are self and continuous cleaning. The first floor laundry is a huge room and doubles as a mudroom to the backyard. The first floor also has a 5th bedroom with an adjacent bathroom that could be a master suite, in-law suite, or used as a den as the current owners have done. Upstairs there are 4 sizable bedrooms and two bathrooms, one in the master and one in the hallway. The master bathroom has all new corian counters, a bulkhead and pot lights. The attic space is floored and is tall enough to stand in. There is also secret storage space in the one bedroom. 2008: tankless water heater and Da Vinci shingle roof with flashing, gutters, and ice breakers. 2010: Amana furnace and RGF Guardian Air Oxidation Cell installed in main air duct. Security system has been updated, sprinklers system installed, and an invisible fence for the dogs is installed. There are many more updates that you will just need to see for yourself! Outside you will enjoy the private backyard on your flagstone patio while using the attached gas grill. The treehouse will stay for your children and their friends to use their imagination. The living room windows have hanging baskets that add a cheerful Spring and Summer touch to the home. The home has an over-sized 2 car integral garage. There is no basement, but there are two rooms in the garage with heat/air ducts and built-in storage shelves. Please call today for your private tour! Julia Snider 412-352-8941… MoreLess
- CoolingCentral
- ParkingUnknown
- Basement TypeUnknown
- FireplaceYes
- Floor CoveringUnknown
- AtticNo
- Parcel #0716S00047000000
- Price/sqft$97
- Roof TypeOther
- Room Count9
- School DistrictNorth Allegheny
- # Stories2.0
- Structure TypeColonial
- Unit Count1
- Zillow Home ID11590947
- Covered Parking Spaces2
- Days on Zillow278
Value | Range | 30-day change | $/sqft | Last updated | |
Zestimate What's this? | $301,267 | $286K – $325K | -$1,055 | $99 | 03/13/2014 |
Rent Zestimate What's this? | $2,585/mo | $2.1K – $3.5K/mo | +$13 | $0.85 | 03/10/2014 |
Owner tools | |||||
Market guide | Zillow predicts 15237 home values will increase 4.3% next year, compared to a 3.1% increase for Mccandless Township as a whole. Among 15237 homes, this home is valued 57.4% more than the midpoint (median) home, but is valued 17.8% less per square foot. Foreclosures will be a factor impacting home values in the next several years. In the 15237 market, the number of foreclosures waiting to be sold decreased 4.3% in the last year. The number of unsold foreclosures is 11.7% less than in Mccandless Township, and 68.5% less than the national average. This lower local number could help 15237 home values rise more quickly than other regions in Mccandless Township. Learn more about forecast calculations or 15237 home values.… MoreLess |
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Item: 849886 Model: RL-913
Theme/design: Alphabet Language: English Duration: Approx. 62 min Title: Letter Sounds Age group and grade: Ages 4 7 Letter ...
Alphabet circus educational DVD teaches the alphabet, letter recognition, and words that begin with each letter. Duration: ...
Theme/design: Multilingual Language: English, Spanish Duration: Approx. 55 min Title: Spanish Vol. I & Vol. II Age group and ...
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Posted Feb 11, 2013
ByPhotos from the 137th Westminster Kennel Club Dog Show in New York. More than 2,700 prized dogs will be on display at the annual canine competition. Two new breeds, the Russell terrier and the Treeing Walker coonhound, will be introduced in the contest.
A Malaysia Airlines flight to Beijing carrying 239 people lost contact with air traffic control Saturday morning, M
Baseball legend, Tommy Lasorda , speaks to coaches and managers of Upland Foothill Little League during opening nig
RIVERSIDE >> An arraignment scheduled for the former educator charged with 16 counts of sex crimes with a minor was
The Rialto Unififed school board accepted the retirement of embattled superintendent Harold Cebrun on Friday, savin
Joey Lagano (22) wins the pole for the NASCAR Kobalt 400 at Las Vegas Motor Speedway in Las Vegas, Nevada Friday Ma
SWAT Team on the scene of a barricaded suspect after a person was shot in the 14400 block of Elmcrest Street in El


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But around 1,500 adults in the region still do not know where, or if, their children will be placed.
Four nursery schools have said they do not have room for Logan Archer, and his mother has spoken out against the current system for favouring those from low income families.
"That gives even younger children preference over my child," said Lee Ann Archer. "I feel that's wrong.
"All children should be treated fairly."
In the South Eastern Education and Library Board area, more than 350 children do not have a place at nursery school, while in Belfast 240 children have missed out.
The shakeup to the preschool admission system was revealed earlier this year and it has left many parents angry.
But Siobhan Fitzpatrick of Early Years said improved provisions are being made for the future.
"There are some pressure points, but we've been able to bring in new nursery school providers for next year," she explained.
In January, the Education Minister said he had added £1.25m to the £50m preschool education budget and John O'Dowd has reiterated that extra cash can be made available if needed.
But Chair of the Education Committee, Mervyn Storey said that is not enough and the policy may discourage employment.
"Many hard-working families are struggling to make ends meet. When they are faced with discriminatory policies such as this they will understandably question the value of being in work.
"This is a bad policy and the Department should move with urgency to address it," he urged.
Tributes amid Cpl McNeill murder probe
Vulnerable adults 'beaten and kicked'
Man tasered as gang steal car
Nails in pipe bombs targeting Romanians
Charges reinstated over Hamill murder
Man shot in both legs in Derry
MLAs warned after 'topless' event
Gold for NI's Gallagher at Paralympics
Men in court over explosives haul
O'Driscoll in emotional Dublin swansong
Irish firm becomes biggest banana supplier
Ray Quinn crowned final ice champion
Linfield beat Ports to stay top
Conservationists work to save NI bees


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Posted Jul 08, 2011
By mleybaCatherine, Duchess of Cambridge and Prince William, Duke of Cambridge celebrate after Williams' team won the Foundation Polo Challenge at the Santa Barbara Racquet and Polo Club on July 9, 2011 in Santa Barbara, California. The event benefits the American Friends of the Foundation of Prince William and Prince Harry, a charity which supports disadvantaged children, conservation and sustainable development, veterans and military families.
More Photos: Royal Couple Arrives In Canada For North American Visit
Mar 12, 2014 | Photo
Police have arrested a man who allegedly stole a vehicle out of Longmont, then carjacked two other vehicles during
Mar 11, 2014 | Photo
March 11, 2014 marks the 10th year anniversary of the Madrid train bombings that claimed 191 lives and injured more
Mar 11, 2014 | Photo
An apartment complex under construction on Fourth Street in the Mission Bay area of San Francisco was destroyed by
Mar 11, 2014 | Photo
Protests reignite due to the death of teenager Berkin Elvan, in Istanbul, Turkey, March 11, 2014.
Mar 11, 2014 | Video
Children's Hospital Colorado and Denver Art Museum offer patients and families an opportunity to create large-scale
Mar 11, 2014 | Photo
Afghan Vice President Marshal Mohammad Qasim Fahim's burial ceremony at the Presidential Palace in Kabul on March 1
This entry was posted on Friday, July 8th, 2011 at 5:59 pm and is filed under News, US National News, World News. You can follow any responses to this entry through the RSS 2.0 feed.
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Hotels for Students in Peru
- 21
Pariwana Hostel
C. Meson de la Estrella 136 | Centro Historico del Cusco, Cusco, PeruRanked #8 overall in Cusco hotels3 reviewsCharming hostel in a 4oo year old colonial house in the center of Cusco, Peru... services was perfect and staff very nice!
Popular withBackpackersBudget$7avg/night
Second Home Peru
Domeyer 366 Barranco, Lima, PeruRanked #2 overall in Lima hotels3 reviewsHotel Class: 3Highly Recommended. Reasonable prices for a beautiful place and excellent service. Unique experience in a breathtaking home overlooking the ocean. There is even a pool on the property which is... more
Popular withBudgetDesignLuxury$115avg/night
Show PricesLowest price guaranteed- 23
LOKI Backpackers Hostel Cusco Peru
Cuesta Santa Ana #601, Cusco, PeruRanked #9 overall in Cusco hotels3 reviews-Very friendly staff -Bar!! Serve a variety of drinks, food, and happy hour from 5-7 and 9:30-10:30 -clean your rooms during the day -controller access -lockers, but bring own locks... more
Popular withBackpackersBudget Inkaterra La Casona
Plazoleta Nazarenas 211, Cusco 00000, PeruRanked #10 overall in Cusco hotels2 reviewsLoved it! Loved the room, loved the location, loved the service! I've stayed at the Monasterio twice and there was no comparison. My stay at La Casona far exceeded my... more
Popular withLuxury$539avg/night
Show PricesLowest price guaranteedRadisson Hotel & Suites San Isidro
Palmeras 240, Lima, PeruRanked #4 overall in Lima hotels2 reviewsHotel Class: 4Great location, amazing food and helpful stuff!
Popular withBusinessBudget$104avg/night
Show PricesLowest price guaranteedSol y Luna Lodge & Spa
Urubamba, PeruRanked #2 overall in Urubamba hotels2 reviewsSol y Luna does a wonderful job of embracing the natural beauty of the Sacred Valley, which lies between Cusco and Machu Picchu. The Lodge & Spa was established in... more
Popular withHistoryLuxury$220avg/night
Show PricesLowest price guaranteedECOPACKERS
Santa Teresa #375, Cusco, PeruRanked #11 overall in Cusco hotels2 reviewsImportant and good place to host with your family when visit Cuzco city to rest and recharge your energy to go to Machu Picchu.
Popular withFamilies$9avg/night
Show PricesLowest price guaranteedRadisson Hotel Decapolis Miraflores
Avenida 28 de Julio 151 | Miraflores, Lima, PeruRanked #5 overall in Lima hotels2 reviewsHotel Class: 4Nice chic hotel within walking distance to the beach and square area in Miraflores. Oh! Check out the breakfast
Popular withBudgetLuxuryNightlife$114avg/night
Show PricesLowest price guaranteedCasa Andina Classic - Cusco Catedral
Santa Catalina Angosta149, Cusco 84, PeruRanked #13 overall in Cusco hotels2 reviewsHotel Class: 3super well located, a couple of blocks from the main square. great service, very comfortable rooms.
Popular withFamiliesBudget$108avg/night
Show PricesLowest price guaranteed- 30
La Morada Suites
Kurkurpata 230Ranked #12 overall in Cusco hotels2 reviewsThis is the best valued beautiful hotel in San Blas of Cuzco, Peru.


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Crystal Paw Three Strand Cuff Bracelet
Let your love for animals shine through with our ravishing bracelet. Triple solid strand ropes tie together the charm of the paw print with the glitz of crystals for a show-stopping piece.
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Blogs Liberty and Power Harvey Silverglate on the Right to Argue with Cops
Jul 30, 2009 9:53 amHarvey Silverglate on the Right to Argue with Cops
As I have said here over the past week, the crux of the matter in the Gates case is that every citizen has a right to argue with a cop. In this superb article, civil libertarian Harvey Silverglate (who has worked closely with the Foundation for Individual Rights in Education) puts forward this view in far more eloquent terms:
It is not yet entirely clear whether there was a racial element to the initial decision by a woman on the street—working for Harvard Magazine, no less!—to call the police, although that is looking unlikely. It remains disputed whether Sergeant Crowley treated Professor Gates any differently than he would treat a white citizen in the same position. (In fact, if one accepts Crowley's claim that he dished out to Gates equal treatment under the law, this case stands as a dire warning to all citizens as to the dangers inherent in exercising one's constitutional right to free speech when in an exchange with a police officer—but more on that below.)Hat tip, Anthony Gregory.
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- Five Things You Need to Know to be a Better Digital Preservationist
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- Harvard Historian Nancy Koehn on Amazon's Tentacular Reach
- Q&A with historian and author Nick Turse


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After booking a mystery 5 star hotel in Queenstown through wotif I was totally in shock , as the first thing is it isn't in Queenstown. , it's actually in Frankton which is 1 km from the airport and 5 Kms from Queenstown , or a 27 dollar taxi fare or a 6.80 bus fare... Anyway after paying a 27... More
- Also Known As:
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Leave the Paper, Take the Cup™ Ceramic Travel Mug
Our travel cup boasts the pure, frill-free utility of the classic take-out cup, but with double walled ceramic insulation and a snug, heat resistant silicone lid to use again and again and again. Imagine all the trees you'll save with this ingenious upgrade!
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Tags: U.S. Sen. John Cornyn (R-Texas)
Mine Your Way to the Big Show — Mine Expo 2012
Don't miss this year's MinExpo — THE place to go for everything mining.
Have you made plans to attend MinExpo? If not, you should, because it won't happen again for another four years. MinExpo International 2012, scheduled for Sept. 24-26 at ... Read More...
Cornyn votes in support of Cut, Cap, and Balance Act
U.S. Sen. John Cornyn (R-Texas) a member of the Senate Budget Committee, July 22 voted against the motion to table the motion to proceed to H.R. 2560, the Cut, Cap, and Balance Act. After the vote Sen. Cornyn released the ... Read More...
Cornyn on budget: 'We cannot sit on our hands and wait'
U.S. Sen. John Cornyn (R-Texas), a member of the Senate Budget Committee, on July 13 signed on as a co-sponsor of the Cut, Cap, and Balance Act of 2011, which was introduced by Sen. Mike Lee (R-Utah).
"With the President refusing ... Read More...
Texas Sen. Cornyn: 'Jobs numbers are a positive sign that our economy is moving in the right direction'
U.S. Sen. John Cornyn (R-Texas) a member of the Senate Finance and Budget committees, issued a statement on April 1 regarding the U.S. Department of Labor's March jobs report indicating the national unemployment rate has dropped to 8.8 percent.
The statement ... Read More...
TxDOT awarded $34 million for rail
The U.S. Department of Transportation will award the Texas Department of Transportation (TxDOT) $34 million grant to help fund a rail project pivotal to North Texas to support the Tower 55 Multimodal Improvement Project (T55MIP), a critical rail gateway located ... Read More...
- Mike Rowe talks about the dirty topic of educating future workers428 Views
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- Rod Martin receives AggMan of the Year 2013 Award198 Views
- MSHA Assistant Secretary of Labor Main updates NSSGA on recent agency actions194 Views
- NSSGA debuts its new strategic plan172 Views


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Lab Emerald Engagement Ring
Created Lab Emerald
14K White Gold
An extremely classy and elegant choice, this engagement ring features a large, emerald cut gemstone of your choice, surrounded by twelve dazzling diamonds. The intricate design of the band adds a stylish element to this ring, that will sit on your lover's finger, constantly reminding her of your love, and the wonderful life you two are about to share. A beautiful matching diamond wedding band is also available with this ring. and This engagement ring features a 7X5mm emerald-cut-cut center stone, surrounded by 12 sparkling diamonds.
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- Origin: Japan
- Color: H
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- Quantity: 12
- Diamond Carat Weight: 0.12
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once when i was little, i claimed it was a teacher's work day so i wouldn't have to go to school and mom's not an idiot so of course it didn't work, but when we got to the school, we found it was a teacher's work day and that made me think i had super powers so i started trying to kill classmates with my mind to confirm the theory
You thought you had super powers so you immediately attempted to murder everyone
go big or go home
There are two ways you can get through pain. You can let it destroy you, or you can use it as fuel to drive you: to dream bigger, work harder.
— | Taylor Swift (via psych-facts) |


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- Waste Disposal
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Overstock.com Complaint - Sells Defective Merchandise Even After It Has Been Returned--Hides Negative Reviews
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I purchased 8 Panels of their Signature Faux Silk Taffeta, TWICE. The first time, I noticed some runs in one panel but mainly returned because of the color and reordered a second 8 panels in another color. I only took out 2 panels of the first order but all of them from the second order to hang and get the full affect. 7 of the 8 panels had gross defects. They had runs going up and down the full length of the panels some of them covering a very wide area. Also, there were holes. They were very evident when there was light behind the panels and is was shocking. 7 out of 8 panels. They went back as well. I wrote a review. Gave them 4 stars but warned at the end of the review to make sure to examine them to make sure they don't have tons of runs in the panels because the light will leak through and really show them. I called to inquire where my feedback was and they told me it would be published shortly. When I have left good feedback, it's up right away. To date, the feedback never appeared. I will never leave feedback for any Overstock merchandise. They obviously were returned, you could tell my the headers where the hooks go that hooks were there before and they turned around and resold them knowing they were defective. I ended up buy from Linens and Things real silk dupioni panels. They were much more expensive but I'm not going to pay almost $100 a panel to be sent crap. They will not publish negative feedback and I'm certain there must be hundreds more feedbacks just like mine that never got published. I will avoid Overstock in the future. All the time I wasted waiting for panels and returning them twice. It's best to go where you can order swatches and find the color or pattern you are looking for and then trust you are dealing with a reputable company. I did think Overstock was good once, and really, they are just selling to suckers. You can actually find similar if not the same merchandise elsewhere for even cheaper, if you must have a deal. Good luck, but don't trust Overstock feedback. They misrepresent their merchandise.
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Posted by Anonymous on 2010-11-12:
I ordered those panels in Sienna - which appeared to be a beautiful rich brick but when they arrived they were pumpkin. They were structurally sound though - no runs or anything like that. I WISH I had returned them but I had something going on and I wanted the curtains up for it so now I am stuck with them. It wasn't that great a deal for faux silk - I think they were about $80 per panel. I will definitely go back to using Penneys for curtains.
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Backlash to Romo Backlash Begins The Cowboys are standing up for Tony Romo. Several members of the team used Monday's chats with the media as a platform to express confidence in Tony Romo after he handed Sunday night's game to the Jets on a silver platter. In the Old West, they'd call it circling the wagons. We don't really have an updated version of the phrase, but it was pretty much the same thing. Keith Brooking: "I'll take that guy over anybody in the league. Y'all might thing I'm crazy, but he's going to have an all-time year. He's going to shatter every record." Dez Bryant: "I know the guys in this locker room wouldn't trade him for nothing. He's the best. He's the real deal. He is the real deal." Jason Witten: "It was a disappointing couple of plays, but that doesn't define who he is. We know what type of player he is, so we'll get back on track. We have all the confidence in the world in him." Read more:http://www.nbcdfw.com/blogs/blue-star/The-Backlash-to-the-Tony-Romo-Backlash-Begins-129719098.html?
Yeah, some of the comments are a bit over-the-top. But the piling on of Romo this week was at a level I've never seen before--especially given that he played an outstanding game outside of a couple boneheaded plays. You expect a backlash to the backlash. We need Romo to be a playmaker, but he needs to continue to learn to harness it. He took a step back in that area the other night. Although his overall QB game continues to get better--and we are not even remotely in postion to win that game without him--his wild hair erased some of the good on at least two occassions.
I agree. The fine line is you don't want him to not be aggressive. When a QB gets gun shy out of fear of mistakes they tend to hold the ball longer and not be as crisp with their passes as to avoid mistakes. On the other hand the QB has to be aware of the situation he faces and know when to take the gamble and when to live to play another play
Same song, 5th verse. Romo is our guy and I think he will have a great year but I don't need to hear circling the wagons talk after the first game. That's ridiculous.
No kidding. It's not a verse you need to hear more than once, either, if you know anything at all about the role of QB in the NFL. Nothing worse than listening to Steve Dennis dismiss Romo's comments after the game as lip service with Laufenberg sitting right there telling him what a good QB Tony is, and how Steve doesn't really understand the numbers or the ups and downs of the position. Crazy.
Just words you know Jerra would get mad ay his playas if they didn't defend Romo....but as a player especially the "D" you have to be pissed for hanging in there and having your QB give the game away... ...they played not to lose under 6 mins to go.


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Building a Snowman Family of 5 Christmas Ornament
Personalized Christmas Ornament
This family of five can't wait for the first snowfall when they go outside as a family and build a snowman together. Everyone has a hand in rolling the three snowballs and each one takes part in the decorating, with dad putting on the black top hat, mom helping adjust the orange carrot nose with the oldest child, the middle child placing the buttons strategically on the front and the youngest giving the snowman a big hug full of love. This personalized family ornament will be sure to be a hit this holiday season and a lasting keepsake on the Christmas tree.
Material: Resin
and credit card.
Ornaments shown on our site are personalized, as examples only, so you can see where we put the words/names you give us. Some ornaments allow you to select hair or uniform color. If there is no color choice, it is not available on that particular ornament. We will do everything possible to catch any mistakes in spelling, etc., but are not responsible if we do as you request, and it is then not correct. The ornament you see above is the way it will look when you get it, except for the personalizing instructions you give us and any optional attributes you select.
Read what our customers say about our Personalized Christmas Ornaments and their shopping experience!
12/9/2009 - "No questions! Just wanted to tell you how much I appreciate your very fast service. Could not believe I placed this on a Thursday and received it today! They are precious. Thanks so much,Diane"
2/25/2009 - "Thank you very much for having this wonderful website. I have been searching for the perfect Christmas ornament to give to my expecting sister and her husband, as she is due in January and baby's first Christmas wouldn't be appropriate. I have finally found the one and I can get it to them with enough time to put it on their tree to enjoy and cherish for the holidays.Melissa M."
10/6/2011 - "VERY PLEASED WITH PAST PURCHASES THAT IS WHY I CONTINUE TO ORDER FROM ORNAMENT SHOP. Gail V."


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Edit Credits- Problem Child (1990) Played by Amy Yasbeck
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Little Ben Healy: [about sending Junior back to the orphanage] But don't you see? We're doing what everybody else has done to him, I mean it's easy to give up on a child.
Flo Healy: Damn straight it is.
Little Ben Healy: But isn't that what's wrong with the world today? People are just looking for the easy way out, like their problems are gonna go away?Problems just don't go, Flo! You know? So the question here is; what are we going to do with our little problem child? I'll tell you what we are going to do. Something that no parent has ever done for him before. We're gonna love him, Flo.
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