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That night dinner was Natalie's choice...hot dogs and mixed veggies. She enjoyed having her dessert a couple hours after her dinner rather than eating all her dessert and snacks with the meal to avoid an extra shot. See that cell phone looking thing next to her plate? That is the pdm that "tells" her pod how much insulin to give her. It also has a blood sugar meter all in one. Thankfully my D-Mom friend told me during our saline trial that we do not need to hold the pdm close to her pod the entire time it is delivering insulin. After the first beep she can run off if she wants. That was getting old keeping her still and holding the pdm up to her bottom waiting for it to complete insulin delivery!
So, what do I love about the pod after 1 week?
We can now give Natalie more accurate amounts of insulin to meet her needs. On shots, we gave her insulin in .50 and 1.0 units. With the pod, we can give her insulin in .05 increments! That is SO COOL to me! For example, this afternoon her blood sugar was 180. Before we would have just let it go and wait until the next meal to bring it down, but I was able to plug in her blood sugar and it calculated that she needed .20 to bring her back into range. With the click of a button she received the insulin and by dinner she was 148!
SLEEPING IN! Natalie has not been able to sleep in in over 2 years because she has always needed to get her morning shot on time. She is my late sleeper too, so it never seemed right to have to wake her up. She (and me) have been sleeping until 9am this week! This won't last long though since school is right around the corner. We still have the weekends though!
NO SHOT PREPARATION! All meal times especially the mornings are much more relaxed now that we do not have to get her shots prepped and administered at each meal. Meal prep used to take so much more time as well. With shots being given in only 1/2 unit increments, I was always trying to get the perfect amount of carbs for her meal so that I could round to the amount I knew worked best for her. (For example, if total carbs came to her needing 1.66 units of insulin, I always tried to add a little more carbs so it came to 1.75 and then would round to 2 units.) Now, if she only wants 7 carbs of strawberries, that is what she gets because the pod can give her the exact amount of insulin needed.
BYE BYE JOURNALS! Since starting on the pod, I have not been writing down every single bite of food that she eats! See all these journals? Those are filled with 2 years of notes documenting every bite of carbs Natalie has eaten at every meal, amount of insulin given, where shot was given, and every blood sugar. I thought this would be hard to give up because I like keeping track of this, but I was able to give it up after one day! I still have a journal where I document her pod changes and anything different that she eats so I can refer to it at another time, but I don't think I will be going through paper like I used to. The pdm stores up to 90 days worth of blood sugars, carbs eaten, and insulin given. I love it! I have already downloaded all her data once and sent it to our CDE to make changes, which also means bye bye manual logs!
NO BIG BLOOD SUGAR DROPS IN THE NIGHT! I know this can change at any time due to growth spurts and activity, but for now I am so amazed at how stable her blood sugar has stayed ALL NIGHT LONG! I was really worried about this because they started her basal rate at only .20 units of insulin every hour. (Basal rate briefly explained is the amount of insulin she needs to keep her steady in between meals and through the day and night.) This comes to only 4.8 units of basal in one day. She was receiving 12 units of lantus (long term) a day (6 in the morning and 6 in the night). When she was on shots, she dropped a LOT in the night despite us giving her a good protein/carb/fiber bedtime snack. We found while on shots if she was not above 130 or so at the 2am check, she needed juice or she would wake up way too low. If she was 130 or lower at the 11pm check and we didn't give her juice then, she would almost always be around 70 or lower by 2am.
We have been checking her blood sugar about every 2 hours, just to make sure she isn't spiking too high or dropping too low. Her blood sugars have been great ALL night long! The first couple nights I was so giddy about how stable she was that I couldn't go back to sleep after checking her at 4am. So we are getting less sleep than before, but hopefully we will feel comfortable enough to drop one of the nighttime checks soon. We've only given her a little juice at 11pm one time because we weren't sure if she would stay steady or not. Not having lantus in her system is a huge difference. I'm so glad to be rid of that one too! We even give her a little bit of insulin when she is above 150 and it brings her back down just beautifully. Here's how her first night on the pod went and she has been pretty much in this range every night, except now we give a teeny amount of insulin to bring the 179 down:
11pm check - 114 (we gave her a little bit of juice)
Midnight check - 179
2am check - 168
4am check - 155
Wake up at 8:45am - 149
SHE CAN EAT WHENEVER SHE WANTS! We are no longer tied to the clock. While on shots, I felt like when my kids were babies and nursing on a schedule. We had to be home to nurse at certain times and everything revolved around their nursing & napping routine. When they were babies the worse thing that happened was they cried the whole way home. With diabetes, there is no pushing the clock....when she needed to eat she HAD to eat or would drop too low, when it was time for a shot, she needed that shot to keep her from going too high.
Some people told us that it is common for kids to gain weight once starting on the pump because they can eat more often. So far she doesn't seem to be eating more than she did before. She is just spreading the same amount of food out throughout the day which makes it much more enjoyable for her. We enjoyed a Starbucks sample the other day and that was so cool to be able to just give her a little bit of insulin for it. She loved that too. We also conquered our first birthday party complete with dinner, cookie & ice cream and FONDUE all at separate times which would have required separate shots. She was a little high (200s), but we got her down eventually. She sure enjoyed the freedom...that was obvious when she grabbed a handful of cheetos with giddy excitement. I wonder how long it will be before I get over the excitement of being able to feed her without a shot? I hope I always feel a bit of this excitement when we enjoy a special treat together and never forget this gift we have been given. It's not all smooth sailing; she still has diabetes; we still must fight highs and lows; she still faces complications if not under "control"; but right now this new freedom feels good.
Natalie excitedly told Eddie the other day that she ate breakfast at 9am and lunch at 1pm. That was living on the wild side for her to eat off of her schedule. It's pretty great to just be able to feed her a sandwich for lunch if we need to be somewhere and she can still snack later on. Things that we took for granted in our "old life" and seem like no big deal to others have given us back a sense of "normal"...just like everyone told us. That has been the biggest thing...a sense of normal. It is all still so new to us and I almost feel like I'm in shock still at some of the freedoms we have been given back that it truly is hard to express just how some of these things that seem little to others seem so huge to us.
What issues and fears do we have with the pod?
POD CHANGES! I have yet to do one by myself and they cause me major anxiety. I fear her crying when the cannula is inserted, hitting muscle instead of fatty tissue (because she doesn't have much), post pod change highs, the pod not sticking, the adhesive not going on smoothly, blood in the cannula, beeping pods that don't work, and other things I don't even know to be afraid of yet! The pod changes do seem to cause her some pain when it is inserted and she cries some, which is so hard. I have to remember that she was getting 5 shots a day before and sometimes she cried with the lantus shot twice a day and sometimes she cried with her arm shots at lunch as well.
Last Saturday, we had to change Natalie's pod for the first time. The pod holds up to 3 days worth of insulin. Actually the minimum it holds is less than Natalie uses in 3 days, so we end up having to throw some out and waste it. I hate that! Insulin is liquid gold to us! We are learning all the beeps that go with the pod and learned that it beeps at the 72 hour mark, but that we have an additional 8 hours until it will deactivate and we MUST change the pod. So naturally, since we were nervous, we kept putting it off. Finally we put the new one on her bottom. All seemed okay with it, in fact her blood sugars were great. An hour or so later we went to the pool with friends. A couple hours after swimming, Natalie said her pod was now on her back. It had completely come off and had moved around in her swim suit. Oh boy...panic set it. Thank goodness for Eddie, because I really didn't know what to do! We had an extra pod and insulin, but decided we needed to go home to get her clean and put the new one on. She started to cry because she didn't want to leave. She asked me if I could just give her the purple shot (long term lantus) so we could stay. We have never really had diabetes mess up our plans like it did this time, so this really ticked me off. Thankfully, we had been there a good amount of time, so it wasn't too awful that we had to leave in a rush. I wasn't really sure how long she could go without the pod and was already worrying about high blood sugars and dka (diabetic ketoacidosis). In retrospect, since she only receives .20 units of insulin an hour and she was sitting pretty at 130, she was probably okay for an hour or so. We put the new one on and she was the same blood sugar an hour later...thank goodness for the activity of swimming keeping her steady and combating any highs. She never even spiked that night. It was frustrating to have lost 100 units of insulin from the first pod though and have to put another one on so soon.
Then on Monday, 2 days into this pod, she was high all morning (300s) and despite continuing to pump her with insulin she would not budge. Ketones were negative and then I noticed a tiny drop of blood in the cannula. I freaked out. I did not want to do a pod change by myself! I decided to wait it out another hour or so and then she dropped to the 200s, so I waited a little more, and then saw that the blood was gone. Sure enough she was down to 180 and then 80 by dinner time! Now, I guess I should have changed the pod when I saw the blood because she was pretty much in the 300s all day. That was a very rough day for me. I felt so frustrated with the pod. Despite her little fingers being pricked over 20 times that day, she was quite a trooper. She wanted me to change the pod because that meant she would get to wear it on her leg. We were able to make it the full 3 days before changing it to her leg and again she is doing beautifully with it on her leg. She seems to be a leg girl for sure! She wore it with pride to her back to school POOL party yesterday with no issues at all. It is still sticking and looking good with great blood sugars. I was an absolute nervous wreck though watching her go down the slide a million times and swimming non-stop. But boy was that fun for her to have a brownie with all the kids and get her insulin without anyone noticing anything different. Tomorrow night we change back to bottom and I'm hoping this time will go better. I think we might have it a little too low. When she sits down it almost touches her seat and seems to get pushed a lot when she pushes off the edge in the pool or rolling around on the couch, etc. I really want this next one to be successful and comfortable for her. We've got another swim party this weekend so we'll be putting it to the test again!
My other main issue right now is trying to get her post breakfast spike under control. Isn't that always an issue with T1D? The Dr. had us increase her basal rate during the day to .25 an hour which is working well for lunch all the way through the rest of the day. She is consistently spiking to over 300 about 90 minutes after breakfast though. This happened on shots, but she always came back down by lunch. I have tried a temp basal increase for that amount of time, but it hasn't really helped. Right now at about 2 hours post breakfast I am correcting by about 1/2 the recommended dose. Sometimes that has her back in range by lunch but not always. So what do you all do to get rid of this breakfast spike? I thought that was one of the benefits of the pump so I want to make that work now! Do you set a temp basal after breakfast, is the basal rate set for more post breakfast, or do you correct a couple hours later?
School starts in less than 2 weeks and I really want to get the mornings under control. I feel so new to this that I don't really even know where to begin with regards to her school schedule. It's completely different without her taking lantus and what to expect with activity and changes between meals. I am SO not ready for her to go back to school. She is not used to having a carb snack mid-morning at school, but now that she is on the pump, she should be able to enjoy that. If she is 300 at that time though, I really don't want her to have a snack.
So we remain cautiously optimistic about life with the pod and look forward to it getting easier with time. It's going better than I expected. I can see why people say it is more work for the parent while on a pump. We can now tweak her insulin needs for every hour of the day, where before there were only so many changes we could make. It should all benefit her in the long run though. I anticipated really high highs because of them being cautious in the beginning, so I can handle a lot of the 200s we have seen. She has an Endo appointment next week and I am dreading the A1C.
Natalie sporting her pod on her leg and holding her very first pod. We decided it was so good to us that we needed to save it forever! (We wrote on it, "My First Pod August 1-4, 1012."


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NAB 2013 From A to Z*
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From The Editor: Holiday Classics
By Cory Sekine-Pettite
Community (NBC) Christmas episode, Dec. 2010.
Image courtesy of Eden FX.
For many of us, one of the great pleasures of the holiday season is watching our favorite Christmas movies and TV specials. Just like the holidays themselves, these shows and films spark childhood memories of innocent times when our only cares were what would be waiting for us under the tree on Christmas morning, or which of our favorite cousins would be waiting for us at our grandparents' house when we arrived for the annual holiday meal.
Like me, it likely was in your grandparents' living room where you watched many of these holiday classics – such as It's a Wonderful Life or Rudolph, the Red-Nosed Reindeer – for the first time. Thus, we have a great deal of affection for these classics (which is why they are referred to as classics in the first place) and tend to make them holiday traditions with our own children. My personal favorites tend to be animated, such as A Charlie Brown Christmas and How the Grinch Stole Christmas. But thinking about these old standards this year has me wondering, are there any "new classics" out there? Are there any recently produced Christmas movies or TV specials that will earn a place among the holiday classics?
Every year there is a new crop of holiday programming and new films in theaters, but can you think of any that deserve to be called classics? The movie, Elf, is funny and airs on TV quite often this time of year, but it's not heart-warming enough to become a classic. Home Alone is much-loved, but again, can one consider it classic? I, for one, cannot. I think Tim Burton has come the closest to producing a new classic with The Nightmare Before Christmas. (Burton wrote and produced the film, which was directed by Henry Selick.) Close, but no cigar, as the saying goes. Don't get me wrong; I adore this claymation film, but I don't anticipate watching it every December. Perhaps there is a younger crowd out there that does.
On television, some more recent programming has tried to acknowledge older TV classics, such as Rudolph, with old-school style animated programs, though they tend to do so with a sense of humor. Last year's Community (NBC) holiday episode (pictured) and the holiday episode of Eureka (Syfy) spring to mind. Both shows were quite funny, especially if you're familiar with the material that is being lampooned, but they're certainly not destined to become classics.
So, what are your favorite holiday shows and movies? Please share your memories and family traditions with us.
NAB 2013 From A to Z*
Markee's annual round up of notable products featured at this year's NAB.
Read more...Rental Houses
Equipment rental houses coast to coast talk what's hot, what's next and their best-kept secrets.
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A blue sky sprawls between ridges frosted in deep evergreen, framing Alder Gulch much as when Native American tribes traversed this landscape 800 years ago. The town of Virginia City sprang up virtually overnight in the summer of 1863; within one year, it was the largest city in the Inland Northwest, with an estimated 10,000 residents. These days, few people continue seeking gold in Alder Gulch. But for filmmakers seeking ready-made Old West locations, the towns of Virginia City and Nevada City offer one more chance to strike it rich.
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Mac Tech: leading the way in LED lighting.

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Only a week ago I spend a couple of days on a beautiful Spanish island called MALLORCA, something I already shared with you in this Insta-preview.
Curious what I was invited for in the first place…?
I was invited by Spanish brand CAMPER to discover their annual workshop for elite design students from all over Europe, this year themed; 'THE SMELL OF DESIGN'
I love to broaden my horizons and I'm always curious how brands build out their empire and how a brand philosophy is build, so now I had the chance to discover everything there is to find out about CAMPER.
It was the 5th time CAMPER organized this workshop but the very first time CAMPER decided to communicate about it, let along invite bloggers to have them share this CAMPER experience with their readers.
Every year, Camper selects design students from different schools in Europe, specialized in footwear and product design. After this selection is made final, CAMPER then invites the graduates to a 10 day workshop at SON FORTESA, a farm house and private family estate from the CAMPER family located in the heart of Mallorca.
The CAMPER folks were so nice to give us a tour around the amazing property.
I took so many pictures worth showing, that I've decided to put them in a proper slide show instead of trying to break to world record of longest blog post éver. :)
This is…SON FORTESA.
In the midst of this paradise, CAMPER gives the designers the opportunity to work in a natural environment, barefooted if they want to and soak them into a 10 day lasting CAMPER experience where they are introduced to the brands design philosphy and are creatively stimulated on the daily to design their own pair of shoes.
To ensure the quality of their creativity, CAMPER provides the designers with everything they might possibly need to finish their task successfully. Professional teachers who guide them, (Adriana Rodriguez, Nunu Solsona from Deux Souliers & Basia Szkutnicka) sun, nature and yes, even a chef who serves them delicious food.
After a tour around the property, CAMPER briefly introduced us to the 9 designers and gave us a peek into the CAMPER workspace.
The workspace looked exactly how you might imagine a space with 9 young creatives in it to be.
A beautiful creative mess:
So what is this CAMPER 'SMELL OF DESIGN' workshop all about?
In a nutshell?
Camper challenged the designers to think about the concept of SMELL. After a speed course where the designers learned everything about smell and the associations that comes with it (memories, moods & cultural values) CAMPER then challenged them to make a shoe that is accompanied by it's own individual smell. Both the shoe and the scent will be showcased at the end of the workshop in a (for this occasion) specially handmade glass bowl or dome.
When you take away the corque and sniff into the dome, you should have…THE SMELL OF DESIGN.
CAMPER also invited some students from ECAL, school for Art & Design in Lausanne, Switzerland, to document, illustrate, film and showcase the workshop and the shoes in a legit exposition. (Daniele Bortotto (Italy), Helge Hjorth (Norway), David Luraschi (France/ U.S.) and January Czarlewski (France/ Poland)
But for now, the workspace smelled like the stress of sweaty students trying to finish of their project before the deadline, so needless to say, we couldn't really hang around for too long.
So, on to the next one and for us this meant, a visit to the CAMPER headquarters!
At the CAMPER headquarters we were introduced to CAMPER LAND from A to Z.
Meaning, the design department, the CAMPER factory, a visit to the infamous CAMPER shoe library (where hundreds of shoes are stocked row after row) the prototype atelier where designs come to life by the hands of a traditional shoemaker, the CAMPER last stock, where all the different type of shoe lasts (in wood or plastic) are created and tested, and yes even a visit to the CAMPER canteen where we were offered a healthy lunch.
We weren't allowed to take much pictures at the CAMPER HQ, but I hope the slide-show gives you an idea from what we saw.
While talking to a few people who work for CAMPER it was very obvious that CAMPER works really hard to inject their 'LIFELOVERS' tag line into the veins of all the people who work for them, and that they do their utmost best to implicate that philosophy into their company management. CAMPER is obviously a big company, and from what I have witnessed, people really, genuinely LOVE to work there.
The next day it was finally time to see what the 9 designers have been working on for the past 10 days at the 'SMELL OF DESIGN' official showcase.
This year's participating designers were: Luc Aarts (Holland) Moe Okoshi (Japan) Sophia Guggenberger (Austria) Steven Tai (Canada) Anna Kobierowska (Poland), Tijn Van Orsou (Holland) Eugenia Morporgu & Michel Giesbrecht (Switzerland) & Eliška Kuchtová (Czech Republic)
My favorite? Hmm though question…
I liked Steven Tai's 'His & Hers' concept, I loved the woven estetics & sand colours from skater boy Luc Aarts, I was stunned by the creativity and skill from Moe Okoshi and I admired the almost perfect execution from the shoe of Michel Giesbrecht, an industrial designer who never made a shoe in his entire life!
So. What did Ì learn from this trip? :)
I learned that CAMPER stands for simplicity, sustainability and comfort, with a passion for design and a quirky wink towards fashion. (for example with their CAMPER TOGETHER capsule collection collaborating with designers like VERONIQUE BRANQUINO & BERNHARD WILLHELM)
I learned that CAMPER is a brand for and by LIFELOVERS, a brand that carries a philosophy that is about loving life and appreciating the simple things like good food, nature and a healthy way of living.
Last but not least, I learned that although you might think CAMPER is not for you or your personal style, I'm pretty sure that CAMPER has at least one pair of shoes that will make you change your opinion.
So next time you walk by a CAMPER store, hop in with this story in the back of your mind, and have a look around.
Meanwhile, I'm dreaming about these CHANTAL heels. (inspired by one of my favorite icons VANESSA -CHANTAL- PARADIS btw)
Thank you CAMPER, I met a dozen interesting and inspiring people in only 2 days and I'm very, very grateful for this experience.
Muchas Gracias.
PS: I already told you in my Insta-Preview that CAMPER made us stay in this amazing hotel called SA CABANA. I took some pictures while I was there, so if these pictures are not convincing enough for you to book a little vacation over there, then I can only say: That shit cray!! ;)
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I recently had the time to watch a moto GP race and i have to say, "that is some real racing". Not that F1 is boring, but they sure can overtake alot!
I always thought that if you can follow a car in a corner than it should be a piece of cake to stab ur car down the inside a take the position. however, watching the monaco race the car following is constantly losing rear grip and therefore are unable to get in the same acceleration rate as the car in front.
From my layman's understanding of aerodynamics, the car in front has to be in a turbulent flow for the car behind to have good tow, but before it hits turbulent flow the car behind is unable to get as much downforce as they need to follow out of a corner, and since rear wings are in the same position, the car behind will alway lose out. its not about the mechanical/aero grip force for the cars its about maintaining the force in a straight line.
So why dont they just allow better diffusors (but non-DDD) and ban the rear wing after all?
yes diffusors lose downforce following as well, but clearly not as much as the rear wing. right??
And as for the front wing? just put is on top of the diffusor's exit and divert the exhaust/heat gas away from the top of the engine cover and thats it~?
Because watching the motoGP race it really gets me thinking, F1 would be more fun if its like this~!!!!


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PHILADELPHIA—After Monday night's game against the Florida Marlins, several of Chase Utley's Phillies teammates told reporters that the All-Star second baseman might be growing "obsessed" with stretching properly and singing in key during the seventh-inning stretch. "He insists that if you don't stretch every major muscle group at that exact moment in time, you risk pulling something," said shortstop Jimmy Rollins, who claimed Utley often forces the entire team to re-sing "Take Me Out to The Ballgame" if they don't perform the song in correct four-part harmony the first time. "Give me a break, man. I don't always feel like eating Cracker Jacks in the middle of a game." Rollins added that he was looking forward to Thursday's game, when he plans to finally inform Utley that the "noise meter" on the Citizens Bank Park JumboTron is not real.
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CLEVELAND—Claiming they want to impose their will against the competition, Cleveland Browns head coach Rob Chudzinski announced Friday that the team is gearing up ...
Skill Difference Between Top, Bottom High School Tennis Seeds Hilarious
PALATINE, IL—During a tennis tournament hosted by Fremd High School, spectators, coaches, and fellow competitors agreed Thursday that the massive gulf in skill levels ...
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Love this store. Tired of my own old stuff I have found wonderful furniture and decorative pieces at reasonable prices here. It's always a good shopping and social experience here as I always find the staff warm, welcoming and knowledgeable about their stock. I try to stop in on a monthly basis just in case there's a new treasure to take home. You can't go wrong shopping here!
LaBelle Antiques Etc
LaBelle Antiques Etc is akin to visiting a friend's home -- but you get to take home some of her stuff. The exterior of the store looks like a campaign headquarters for a political candidate. The interior is moreso a comfortable living room of treasures that you can take with you for a reasonable price. They include tables, chairs, cabinets, china, dresses and lots of minutiae. Displays are updated often and nicely done. The store is a conglomeration of antiques and collectibles from 23 vendors. Some of the items on sale come from estate sales. New stock is put out daily. LaBelle buys stuff from walk-ins, too.
- Hours: 11am-6pm Tuesday-Friday; 10am-3pm; closed Sunday-Monday
- Handicap Accessible: No
- Founding Date: Aug 01 2006
- Payments accepted: Cash, Debit Card, MasterCard, Visa
- Products: Antiques and unique collectibles
- Services: Gift certificates, Shipping
- ATM: No
- Public restrooms: No
- Parking: Free lot
- Private events: No
- Multi-dealer store: Yes
- Number of dealers: 23
Rate This Business
Reviews (2)
I am the store owner, and very proud to say so. We offer a ride array of antiques. Collectables are slim unless you mean depression glass, toys, postcards, jewelry and more. You won't find reproductions in the store either. I am blessed to have the hardest working vendors and best customers. It reminds me of the old barbershop environment. If you want to learn more about us, you can find us on facebook. or call me (586)445-3144


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In JoVE (2)
- Isolation and Expansion of Human Glioblastoma Multiforme Tumor Cells Using the Neurosphere Assay
- Identification and Isolation of Slow-Dividing Cells in Human Glioblastoma Using Carboxy Fluorescein Succinimidyl Ester (CFSE)
Other Publications (7)
Articles by Loic P. Deleyrolle in JoVE
Isolation and Expansion of Human Glioblastoma Multiforme Tumor Cells Using the Neurosphere Assay
Hassan Azari1,2, Sebastien Millette1, Saeed Ansari1, Maryam Rahman1, Loic P. Deleyrolle1, Brent A. Reynolds1
1Department of Neurosurgery, University of Florida, 2Department of Anatomical Sciences, Shiraz University of Medical Sciences
This video protocol demonstrates the isolation and expansion of stem like cells from surgically resected human glioblastoma mutliforme (GBM) tumor tissue using the neurosphere assay culture method.
Identification and Isolation of Slow-Dividing Cells in Human Glioblastoma Using Carboxy Fluorescein Succinimidyl Ester (CFSE)
Loic P. Deleyrolle1, Mark R. Rohaus1, Jeff M. Fortin1, Brent A. Reynolds1, Hassan Azari1,2
1Department of Neurosurgery, The University of Florida, 2Department of Anatomical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
This video protocol demonstrates the application of the fluorescent dye carboxyfluorescein succinimidyl ester (CFSE) for the identification and separation of different sub-populations of cells in human glioblastoma based on frequency of cell division.
Other articles by Loic P. Deleyrolle on PubMed
Isolation, Expansion, and Differentiation of Adult Mammalian Neural Stem and Progenitor Cells Using the Neurosphere Assay
Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19378198
During development and continuing into adulthood, stem cells function as a reservoir of undifferentiated cell types, whose role is to support cell genesis in several tissues and organs. In the adult, they play an essential homeostatic role by replacing differentiated cells that are lost due to physiological turnover, injury, or disease. The discovery of such cells in the adult mammalian central nervous system (CNS), an organ traditionally thought to have little or no regenerative capacity, has opened the door to the possibility of designing innovative regenerative therapeutics, an unexpected concept in neurobiology 15 years ago. In 1992, to detect precursor cells in the adult brain, we employed a serum-free culture system whereby the majority of primary differentiated CNS cells did not survive but a small population of EGF-responsive cells were maintained in an undifferentiated state and proliferated to form clusters, called neurospheres (Reynolds and Weiss, Science 255:1707-1710, 1992). These neurospheres could be (a) dissociated to form numerous secondary spheres or (b) induced to differentiate, generating the three major cell types of the CNS. This chapter outlines the adult mammalian NSC culture methodology and provides technical details of the neurosphere assay to achieve reproducible cultures.
Identifying and Enumerating Neural Stem Cells: Application to Aging and Cancer
Progress in Brain Research. 2009 | Pubmed ID: 19660648
The discovery of stem cells in the adult central nervous system implied the potential for endogenous repair and exogenous cell-based therapeutics. The development of experimental protocols, like the neurosphere assay and the neural-colony forming cell assay, enable the accurate and meaningful investigation of neural stem cell properties and allow the exploration of mechanisms related to the role of neural stem cells in aging and cancer.
Determination of Somatic and Cancer Stem Cell Self-renewing Symmetric Division Rate Using Sphere Assays
PloS One. 2011 | Pubmed ID: 21246056
Representing a renewable source for cell replacement, neural stem cells have received substantial attention in recent years. The neurosphere assay represents a method to detect the presence of neural stem cells, however owing to a deficiency of specific and definitive markers to identify them, their quantification and the rate they expand is still indefinite. Here we propose a mathematical interpretation of the neurosphere assay allowing actual measurement of neural stem cell symmetric division frequency. The algorithm of the modeling demonstrates a direct correlation between the overall cell fold expansion over time measured in the sphere assay and the rate stem cells expand via symmetric division. The model offers a methodology to evaluate specifically the effect of diseases and treatments on neural stem cell activity and function. Not only providing new insights in the evaluation of the kinetic features of neural stem cells, our modeling further contemplates cancer biology as cancer stem-like cells have been suggested to maintain tumor growth as somatic stem cells maintain tissue homeostasis. Indeed, tumor stem cell's resistance to therapy makes these cells a necessary target for effective treatment. The neurosphere assay mathematical model presented here allows the assessment of the rate malignant stem-like cells expand via symmetric division and the evaluation of the effects of therapeutics on the self-renewal and proliferative activity of this clinically relevant population that drive tumor growth and recurrence.
Evidence for Label-retaining Tumour-initiating Cells in Human Glioblastoma
Brain : a Journal of Neurology. May, 2011 | Pubmed ID: 21515906
Individual tumour cells display diverse functional behaviours in terms of proliferation rate, cell-cell interactions, metastatic potential and sensitivity to therapy. Moreover, sequencing studies have demonstrated surprising levels of genetic diversity between individual patient tumours of the same type. Tumour heterogeneity presents a significant therapeutic challenge as diverse cell types within a tumour can respond differently to therapies, and inter-patient heterogeneity may prevent the development of general treatments for cancer. One strategy that may help overcome tumour heterogeneity is the identification of tumour sub-populations that drive specific disease pathologies for the development of therapies targeting these clinically relevant sub-populations. Here, we have identified a dye-retaining brain tumour population that displays all the hallmarks of a tumour-initiating sub-population. Using a limiting dilution transplantation assay in immunocompromised mice, label-retaining brain tumour cells display elevated tumour-initiation properties relative to the bulk population. Importantly, tumours generated from these label-retaining cells exhibit all the pathological features of the primary disease. Together, these findings confirm dye-retaining brain tumour cells exhibit tumour-initiation ability and are therefore viable targets for the development of therapeutics targeting this sub-population.
Isolation and Characterization of Adult Neural Stem Cells
Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21618083
It has been thought for a long time that the adult brain is incapable of generating new neurons, or that neurons cannot be added to its complex circuitry. However, recent technology has resulted in an explosion of research demonstrating that neurogenesis, or the birth of new neurons from adult stem cells constitutively occurs in two specific regions of the mammalian brain; namely the subventricular zone and hippocampal dentate gyrus. Adult CNS stem cells exhibit three main characteristics: (1) they are "self-renewing," i.e., they possess a theoretically unlimited ability to produce progeny indistinguishable from themselves, (2) they are proliferative (undergoing mitosis) and (3) they are multipotent for the different neuroectodermal lineages of the CNS, including the different neuronal, and glial subtypes. CNS stem cells and all progenitor cell types are broadly termed "precursors." In this chapter, we describe methods to identify, isolate and experimentally manipulate stem cells of the adult brain. We outline how to prepare a precursor cell culture from naive brain tissue and how to test the "stemness" potential of different cell types present in that culture, which is achieved in a three-step paradigm. Following their isolation, stem/progenitor cells are expanded in neurosphere culture. Single cells obtained from these neurospheres are sorted for the expression of surface markers by flow cytometry. Finally, putative stem cells from cell sorting will be subjected to the so-called neural colony-forming cell assay, which allows discrimination between stem and progenitor cells. At the end of this chapter we will also describe how to identify neural stem cells in vivo.
Purification of Immature Neuronal Cells from Neural Stem Cell Progeny
PloS One. 2011 | Pubmed ID: 21687800
Large-scale proliferation and multi-lineage differentiation capabilities make neural stem cells (NSCs) a promising renewable source of cells for therapeutic applications. However, the practical application for neuronal cell replacement is limited by heterogeneity of NSC progeny, relatively low yield of neurons, predominance of astrocytes, poor survival of donor cells following transplantation and the potential for uncontrolled proliferation of precursor cells. To address these impediments, we have developed a method for the generation of highly enriched immature neurons from murine NSC progeny. Adaptation of the standard differentiation procedure in concert with flow cytometry selection, using scattered light and positive fluorescent light selection based on cell surface antibody binding, provided a near pure (97%) immature neuron population. Using the purified neurons, we screened a panel of growth factors and found that bone morphogenetic protein-4 (BMP-4) demonstrated a strong survival effect on the cells in vitro, and enhanced their functional maturity. This effect was maintained following transplantation into the adult mouse striatum where we observed a 2-fold increase in the survival of the implanted cells and a 3-fold increase in NeuN expression. Additionally, based on the neural-colony forming cell assay (N-CFCA), we noted a 64 fold reduction of the bona fide NSC frequency in neuronal cell population and that implanted donor cells showed no signs of excessive or uncontrolled proliferation. The ability to provide defined neural cell populations from renewable sources such as NSC may find application for cell replacement therapies in the central nervous system.
YB-1 Bridges Neural Stem Cells and Brain Tumor-initiating Cells Via Its Roles in Differentiation and Cell Growth
Cancer Research. Aug, 2011 | Pubmed ID: 21730024
The Y-box binding protein 1 (YB-1) is upregulated in many human malignancies including glioblastoma (GBM). It is also essential for normal brain development, suggesting that YB-1 is part of a neural stem cell (NSC) network. Here, we show that YB-1 was highly expressed in the subventricular zone (SVZ) of mouse fetal brain tissues but not in terminally differentiated primary astrocytes. Conversely, YB-1 knockout mice had reduced Sox-2, nestin, and musashi-1 expression in the SVZ. Although primary murine neurospheres were rich in YB-1, its expression was lost during glial differentiation. Glial tumors often express NSC markers and tend to loose the cellular control that governs differentiation; therefore, we addressed whether YB-1 served a similar role in cancer cells. YB-1, Sox-2, musashi-1, Bmi-1, and nestin are coordinately expressed in SF188 cells and 9/9 GBM patient-derived primary brain tumor-initiating cells (BTIC). Silencing YB-1 with siRNA attenuated the expression of these NSC markers, reduced neurosphere growth, and triggered differentiation via coordinate loss of GSK3-β. Furthermore, differentiation of BTIC with 1% serum or bone morphogenetic protein-4 suppressed YB-1 protein expression. Likewise, YB-1 expression was lost during differentiation of normal human NSCs. Consistent with these observations, YB-1 expression increased with tumor grade (n = 49 cases). YB-1 was also coexpressed with Bmi-1 (Spearmans 0.80, P > 0.001) and Sox-2 (Spearmans 0.66, P > 0.001) based on the analysis of 282 cases of high-grade gliomas. These proteins were highly expressed in 10/15 (67%) of GBM patients that subsequently relapsed. In conclusion, YB-1 correlatively expresses with NSC markers where it functions to promote cell growth and inhibit differentiation.


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New Children's First Chapter Books
New arrivals added to our Children's First Chapter Books Collection in the last 7 days
Title | Date added | |
Batter up! by Scaletta, Kurtis. |
While on the disabled list and with his replacement hitting a winning streak, left-fielder Danny O'Brien wants one of batboy Chad's "magic" baseball cards to get back in the game. |
May 19, 2013 |
Bink & Gollie, best friends forever by DiCamillo, Kate. |
May 19, 2013 |
Bink & Gollie, two for one by DiCamillo, Kate. |
"The state fair is in town, and now Bink and Gollie-utter opposites and best friends extraordinaire-must use teamwork and their gray matter while navigating its many wonders. Will the energetic Bink win the world's largest donut in the Whack-a-Duck game? Will the artistic Gollie wow the crowd in the talent show? As the undaunted duo steps into the mysterious tent of fortune-teller Madame Prunely, one prediction is crystal clear: this unlikely pair will always be the closest of pals"-- |
May 19, 2013 |
Bramble and Maggie - give and take by Haas, Jessie. |
"Bramble the horse is starting life with her new person, Maggie. When Maggie wants to go for a ride, Bramble is hesitant because she feels that neither she nor Maggie should be boss all the time. There should be some give-and-take. Maggie agrees, and a carrot seals the deal."--Dust jacket. |
May 19, 2013 |
Brianna the Tooth Fairy by Meadows, Daisy. |
When Jack Frost steals her magic items in an attempt to ward off toothache, Brianna the Tooth Fairy is no longer able to collect teeth from beneath children's pillows! But as ever, Kirsty and Rachel are eager to help. Can they find all three missing objects -- and persuade Jack Frost to go to the dentist? |
May 19, 2013 |
Claude in the city by Smith, Alex T. |
When Claude, a small, plump dog, and his friend, Sir Bobblysock, visit the city Claude heroically, if accidentally, stops a thief, then, when Sir Bobblysock becomes ill, Claude rushes him to a hospital and is mistaken for a doctor. |
May 19, 2013 |
Close shave by Larry, H. I. |
Zac's favourite hair gel has been spiked with a hair-removing ingredient. The only antidote is being held for ransom. If Zac can't find the culprits, the entire town, including Zac himself, will be bald within a day. No-one messes with Zac's hair... This time, it's personal! Age 6+. |
May 19, 2013 |
Daisy's defining day by Feder, Sandra V., 1963- |
When Miss Goldner teaches her class about alliteration, Daisy has a terrific time coming up with wonderful word combinations. Then someone calls her Lazy Daisy, and suddenly words are a problem. Daisy needs a new nickname! - from cover p. [2] |
May 19, 2013 |
Dodsworth in Tokyo by Egan, Tim, 1957- |
Dodsworth's duck companion is surprisingly well-behaved during a visit to Tokyo, although he does fall into the koi pond at the Imperial Palace and becomes the center of attention at a Sanja Festival. |
May 15, 2013 |
Double trouble by Press, Judy, 1944- |
When Sam Dibble decides to run for third grade class president, mainly to keep his nemesis Wax from winning, he will need more than his doodles to convince his classmates that he can be a good leader. |
May 19, 2013 |
Hello, Nebulon! by O'Ryan, Ray. |
Moving from Earth to the futuristic planet Nebulon in 2120, eight-year-old Zack is nervous about starting school and meeting people. |
May 19, 2013 |
Horrid Henry and the abominable snowman by Simon, Francesca. |
Horrid Henry builds a big, mean monster snowman in order to win the snowman competition against Moody Margaret's ballerina snowgirl, and claim the prize--a year's supply of ice cream--all for himself. Plus three more stories that go well with ice cream. |
May 19, 2013 |
Horrid Henry and the zombie vampire by Simon, Francesca. |
May 19, 2013 |
Horrid Henry robs the bank by Simon, Francesca. |
May 19, 2013 |
Horrid Henry's monster movie by Simon, Francesca. |
Horrid Henry has found a new way to scare everyone, his very own monster movie. The Undead Demon Monster Who Would Not Die is going to be a BIG hit! Plus three more monstrous tales that will leave you screaming for more. |
May 19, 2013 |
Horrid Henry's stinkbomb by Simon, Francesca. |
"Horrid Henry and Moody Margaret are a perfect pair. Henry has a secret club that doesn't allow girls in. Margaret has a secret club just for girls. And both Henry and Margaret love to play pranks. But with Perfect Peter and Sour Susan acting as spies, which secret club will win?"--P. [4] of cover. |
May 19, 2013 |
Horrid Henry's underpants by Simon, Francesca. |
Contains four stories that follow the adventures of Horrid Henry, including the title work in which Henry realizes, much to his chagrin, that he has accidently worn the bright pink "big girl" panties his goofy great-aunt Greta sent him for his birthday. |
May 19, 2013 |
I was a third grade spy by Auch, Mary Jane. |
When Brian's dog Arful suddenly begins talking, Brian and his two friends send the dog to find out what their classmates are planning for the school talent show. |
May 19, 2013 |
Journey to Juno by O'Ryan, Ray. |
On the planet Nebulon in 2120, Zack joins his school's Explorer's Club and visits Juno, a planet made of crystals, but he is less than thrilled when he is partnered with the class bully. |
May 19, 2013 |
Robot rumble by Dixon, Franklin W., author. |
"Bayport Elementary's annual science fair is here, and Frank, Joe, and their friend Phil are determined to win. But the morning of the fair, Phil discovers that their awesome homemade robot has gone missing!"--Page [4] of cover. |
May 19, 2013 |
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Arthritis Specialists in Stoneboro, PA
File James C MD - Stoneboro, PA - Phone: (724) 376-3175
Life Care Cancer Center - Stoneboro, PA - Phone: (724) 376-7845
Miller James P Jr PhD - Stoneboro, PA - Phone: (724) 376-2702
Helpful Definition for: Arthritis Specialists
'Arthritis Specialists' are medical professionals who are responsible for providing treatment to patients affected with arthritis. There are many forms of arthritis, the common being osteoarthritis and rheumatoid arthritis in Stoneboro. For treating them, clinical tests like blood tests, radiology,etc, are done and after the detection, arthritis specialists give the necessary treatment for their recovery. In Stoneboro, the treatment differs according to the type of arthritis detected and arthritis specialists treat them accordingly.
At the beginning of medication, the arthritis specialists in Stoneboro give medicines having less power and increase as and when required. In Stoneboro, both physical as well as occupational therapy is given by the arthritis specialist for relieving the patients from the excruciating pain of arthritis.
Recent News from the Green Blog
What's the Harm? Studies Show GMOs May Cause Plenty
Written by: Lee Ann Rush Recent legislation dubbed the "Monsanto Protection Act" has put the controversy over genetically engineered (GE) foods* back into the headlines, as research continues to identify more and more negative effects resulting from the proliferation of these "Frankencrops." GE foods are those which have had their genetic composition altered in order to add a "desirable" trait..


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Greyhound (< 500 Yards away) Black Buoy (< 500 Yards away) Rose & Crown (< 500 Yards away) Horse & Groom Inn (0.8 miles away) Flag Inn (1.0 miles away) Beehive (2.8 miles away)Location
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Wivenhoe See map: Google Maps
01206 822991
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Get involved: send your pictures, video, news and views by texting GAZETTE NEWS to 80360, or email
4:47pm Friday 7th September 2012 in News
A WOMAN was sexually assaulted in Colchester town centre.
Police are appealing for information after the woman was attacked in Vineyard Street between 3am and 4am yesterday.
The woman, aged in her 20s, was approached by a man who then assaulted her.
She managed to break free and run back along Queen Street to safety.
PC Rachel Evemy said: "The victim was visibly upset when she ran along Queen Street after the incident and states she ran past people who may have seen her.
"We are asking anyone who was in the area at the time or who saw a woman upset around this time to contact us."
Anyone with any information call PC Rachel Evemy on 101, or Crimestoppers anonymously on 0800 555111.


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"Four varieties of beans, crispy bacon, and Parmesan cheese are baked into a deliciously simple side dish everyone will enjoy." - by CARISHERIDAN
Adjust Servings
Original recipe yields 12 servings
- Preheat oven to 350 degrees F (175 degrees C).
- Cook and stir bacon in a large, deep skillet over medium-high heat until evenly browned, about 10 minutes. Drain the bacon slices on a paper towel-lined plate.
- Mix bacon, baked beans, kidney beans, pinto beans, chili beans, brown sugar, ketchup, and Worcestershire sauce together in a bowl. Pour into a large baking dish; top with Parmesan cheese.
- Bake in the preheated oven until bubbling and cheese is melted, about 45 minutes. Set aside to cool for 20 minutes before serving.
Amount Per Serving (12 total)
- Calories
- 358 cal
- 18%
- Fat
- 7 g
- 11%
- Carbs
- 62 g
- 20%
Based on a 2,000 calorie diet
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We had so much fun today at Beginagin Theme Park!
In Large Group, Zip told Andy that she was not ok because something strange is going on in the park . The days are beginning again each day! Since Zip was able to tell Andy that she was not ok, they were able to start trying to figure out what was going on! Zip and Andy learned from a story Wil Winagin told us from Mark 5-21-43, Luke 8-40-56, and Matthew 9-18-26. We learned It's OK To Not Be Ok!
Come back next week to see what else we learn from Zip and Andy!
This Sunday in KidSpring, preschoolers went Off the Rails to learn that "God Cares For Me!" We saw how God cares for us through a Bible story called "Jars of Oil" in 2 Kings 4:1-7. See our friend Zingo tell this true story by clicking below. Check back later this week to find out how preschoolers learned "God Cares For Me" in small group!
Every week preschoolers in KidSpring are encouraged to follow two rules: Be Kind & Be Safe! Click below to see how Zany Lainey reminds us of these rules during our Off the Rails at SpringTown Fun Park series. Maybe these rules will work for your family, too!
One reason preschoolers can say "I Love My Church!" is because KidSpring is a fun place where they learn about Jesus on their level. Each week, older preschoolers have fun making a craft! This week they made postcards to use to invite their friends to church (see below).
When we invite people to church, we are like the first church in Acts that we learned about this Sunday. Help your child invite someone to church this week by giving them or mailing them the postcard your preschooler had fun creating this Sunday!
We had so much fun this week at Beginagin Theme Park!
In large group, Zip and Andy Made their way to the top of the leaderboard of the Ultimate Theme Park Challenge by riding the Farris Wheel 8 times to gain 800 points each! Then, Fil Finagin announced that the person at the bottom of the leaderboard was going to be taken out of the competition unless someone wanted to give some of their points away. Zip and Andy decided to work together to each give away 500 points. By working together, they were able to do something great!
Wil Winagin told us the story of the Early Church from Acts 2:42-47. From this story, we learned God Does Great Things Through His Church!
Kids had a special assignment in small group to show that God STILL does great things through his church today. We're asking every K-5th grader to bring ONE can of food with them to church next week. Together, everyone in KidSpring will be able to help our community more than we could on our own!
If you want a reminder about the canned food drive, you can subscribe to our Twitter feed!


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Lease Equipment With A Equipment Finance Broker
To work well, every organization spread across all sectors, whether brand-new or growing (from big corporations, business homes, multinationals to neighborhood and state Government as well as small to medium businesses) needs an appropriate stock of devices to facilitate the process of growth and growth. The term equipment consists of almost every little thing in its gamut-- machinery, furniture, a brand-new manufacturing line and more. Though the requirement for inventory is all-pervasive, it is not constantly easy to finance such big devices without the assistance of funding options such as Equipment Loans and Equipment Lease.
Equipment Finance Brokers | Equipment Leasing Broker
Try to find a skilled equipment finance broker that has been in the sector and are experienced and trained to handle the funding requirements of small medium enterprises in addition to large business companies. A broker that deals in equipment finance in large volumes of equipment finance and lease negotiations.
How A Broker Ought to Function
They need to do things right the first time round and to this end, with loan specialists start by first understanding your existing company framework and future business objectives.
Depending on your tax returns-- capital, credit score, operating history etc, they help you in narrowing down to the finest equipment finance option ideal for you-- an Equipment Loan or an Equipment Lease.
Considering that the equipment that is bought by making use of an equipment loan or a lease is the very thing that is used as security for that loan or lease, it is important to understand the viability of both prior to securing and picking any equipment loans choice.
1. An Equipment Loan is usually ideal for those firms that have a great operating history and credit score. The loan is taken with the equipment being bought as the security.
2. An Equipment Lease is perfect for companies who wish to benefit from a lower credit requirement and like to pay rent with respect to the equipment being made use of for a certain determined period of time.
IT Equipment Finance to Heavy Equipment Finance
A financial equipment loans broker of Equipment Financing could arrange equipment loan finance from little office IT equipment loans to heavy equipment finance.
Solutions should include chattel mortgage, commercial hire purchase, equipment lease, fully maintained equipment lease, rentals and, structured equipment loans, and no doc equipment finance.
Discover experts in the industry of fast and precise Equipment Funding, we have the know-how to offer interest loan rate of interest that are considerably lesser that a lot of banks.
Time is money. Thus, when you employ a equipment finance broker, you can be assured of timely and tailored service provided to you with our skilled and efficient loan experts who know their job well. No loan application delays or inconveniences!


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The WWW Virtual Library | Main Ratings PageDAVID
Follow the wilsonpages Twitter in the Off-Season.Site Map to other ratings. Top of Directory: American College Football Links
After the ratings,
you will find a date or green light ()
if they are up to date. New addition in the works: The Ultimate College Football Listing UPDATED 2 March 2013
Personal Rankings and Predictions


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Kabi Cafe
Just about anything you find on TravelOregon.com can be added to your own personal Trip Planner. Find out how.
Seven Feathers Casino Resort's newest and most convenient eatery is open daily at 6 a.m. Located beside the Gift Gallery and across from the Arcade. Check out the Barista Specials. Enjoy a healthy or Continental style breakfast! Grab a bite on the go or a sweet treat. Check out the daily posted specials!
What's around here? Location & Nearby Things to See & Do
Is any of the information on this page incorrect?


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NYCC Exclusives
We've put some of the NYCC Exclusives up on the webstore. Get them while they're up. Once they are sold out, that's it.
A band of survivors struggles to survive after an epidemic of apocalyptic proportions has swept the globe, causing the dead to rise and feed on the living.
Every kid wants superpowers. But not every kid's father is Omni-Man, the greatest superhero the world has ever known. When teenager Mark Grayson finally inherits his dad's abilities, though, he realizes life isn't getting any easier.
Thief of Thieves tells the story of Conrad Paulson, the world's greatest thief, who has set his sights on his own kind. He vows to steal only what's already been stolen, in an effort to right the great wrongs of his life.
Dr. Luke Taylor's perfect life comes to a dramatic halt when an identical, bloodied version of himself arrives at his doorstep with news that he is one of many clones... and they're all after his pregnant wife and their unborn child!
It's a sick world, and Dr. Vincent Morrow's here to treat it. Headhunted into an exciting new career in the black arts after his excommunication from the medical community, Morrow serves the world with both hands -- one in magic, one in medicine -- as earth's protector. Earth's Witch Doctor.
The Guardians of the Globe are BACK in an all-new, all-exciting ongoing series! Your favorite heroes - Brit, Outrun, Invincible, Robot, Yeti, Kaboomerang, and more -face new challenges of epic proportions in stories by the all-star team of Phil Hester & Todd Nauck!
The Evil Max Maximus wants to get to Inner-Earth! He wants the dinosaurs that live there! He wants the powerful DynOre mineral that originates there! SUPER DINOSAUR and DEREK DYNAMO are the only ones who can stop him!
Fight fire with fire. Fight evil with science! Collecting the never before reprinted Science Dog back-up story from INVINCIBLE #75, as well as the ALL-NEW full-length, never-before-seen conclusion of the story!
After the Rapture the sole protector of the sinning masses is BATTLE POPE, and his trusty sidekick, Jesus. They're the last line of defense in a world overrun with demons and depravity.
When Gary Hampton, corporate CEO, is mauled and left for dead following an attack by a wolf on a family vacation, his life takes a drastic turn! Gary is cursed -when the moon is full he transforms into a beast of the night - a werewolf!
Meet Brit, the government's last line of defense when it comes to the really messy parts of keeping the world safe. When super-powered menaces threaten our home soil, send in this one-man killing machine: He's indestructible, unstoppable, and eligible for a senior citizen's discount.
Freedom fighter Bowen has lost everything in the war against The Infinite. His only hope is to travel back in time to prevent their world domination before it starts! Bowen can't do this alone, he must turn to the only ally he knows he can trust: HIMSELF.
We've put some of the NYCC Exclusives up on the webstore. Get them while they're up. Once they are sold out, that's it.
Ok, I've been waiting patiently until we could announce the last few Walking Dead exclusives for NYCC.
First off we have the limited edition Michonne and pets PVC figures. There are three color variants, broken down as follows:
Grey - Limited to 1000. $15 each.
Purple - Limited to 250. $20 each.
Glow in the Dark - Limited to 250. $20 each.
Lastly we have The Walking Dead "The Remains" t-shirt.
This is an homage to the classic "Great Seal" t-shirt. The price is $20 each and it is limited to 250 shirts.
And if you want more info, hit the jump.
Hey Skybounders!
Once again Skybound is heading to NYCC! We've got some great things lined up from panels to signings to exclusives.
Check out all of the infomation below!
The Walking Dead creator/writer Robert Kirkman and Skybound, his imprint at Image Comics, have special items and events planned for this year's New York Comic-Con from October 10-14th. At NYCC, Kirkman will participate in panels including a question and answer session about his work, and a panel discussing the success of Skybound. Skybound will also debut two new hardcovers at NYCC: The Walking Dead Hardcover Compendium (Red Foil Version) will be a limited edition of 1500 for $100. The first-ever Thief of Thieves Hardcover, Volume 1, "I Quit" will debut with a limited edition of 1000, available for only $30. Both may be purchased at the Skybound booth, #1229, along with all your favorite Skybound titles, t-shirts and merchandise.
In New York, Kirkman will also be signing copies of The Road to Woodbury, his and Jay Bonansinga's latest Walking Dead novel for St. Martin's Press. The book is the sequel to last year's bestseller, The Rise of the Governor, and will be released October 16th.
Skybound will also keep you posted on where you can buy The Walking Dead: The Official Magazine, which debuts from Titan/Skybound on October 23 and features an interview with Kirkman and The Walking Dead artist Charlie Adlard, and is chock full of art, news and interviews from the entire The Walking Dead universe.
Two beautiful Skybound hardcovers will debut at NYCC. First up, The Walking Dead Hardcover Compendium (Red Foil Version) will be a limited edition of 1500 for $100. Next up, the first-ever Thief of Thieves Hardcover, Volume 1, "I Quit." will debut with a limited edition of 1000, available for only $30. Both may be purchased at the Skybound booth, #1229, along with all your favorite Skybound titles, t-shirts and merchandise.
You've been dying for the latest news on Witch Doctor and creator/writer Brandon Seifert and creator/artist Lukas Ketner will be there to entice you with details about the November 28 release of Witch Doctor: Mal Practice #1. Also, come welcome editorial director Sean Mackiewicz as the newest member of the Skybound team.
Skybound Panels:
Skybound: On the Rise
Robert Kirkman, Shawn Martinbrough, Jason Howard & special guests
moderated by Sean Mackiewicz
Date: 10/12/2012 Friday
Time: 2:45PM - 3:45PM
Location: 1A14
(seating capacity 350)
There's no limit on what to expect from Skybound, Robert Kirkman's imprint at Image Comics. Thief of Thieves is already a breakout hit that has been optioned by AMC, Guarding the Globe supplies another monthly fix for the Invincible universe, and the all-ages smash Super Dinosaur is about to blow up in a big way. Join Robert Kirkman as he discusses the imprint's future with his stable of creators, including the creative teams behind Thief of Thieves, Witch Doctor and more!
Robert Kirkman takes questions from the audience
Date: 10/14/2012 Sunday
Time: 1:30PM - 2:30PM
Location: 1E13
(seating capacity 1200)
Robert Kirkman, creator of the global sensations The Walking Dead, Invincible and Thief of Thieves, opens the floor to all his fans in this lively and engaging Q&A session.
Skybound Signings:
Thursday, October 11th:
5:00PM-6:00PM Robert Kirkman signing, creator/writer of The Walking Dead, Invincible, Super Dinosaur and Thief of Thieves
Friday, October 12th:
1:00PM-2:00PM Thief of Thieves signing with artist Shawn Martinbrough, writer James Asmus and colorist Felix Serrano
4:00PM-5:30PM Robert Kirkman signing, creator/writer of The Walking Dead, Invincible, Super Dinosaur and Thief of Thieves
TBD Robert Kirkman and Jay Bonansinga sign advance copies of their upcoming novel, The Road to Woodbury. For further details, keep checking www.Skybound.com
Saturday, October 13th:
1:00PM-2:00PM Witch Doctor signing with creator/writer Brandon Seifert and creator/artist Lukas Ketner
5:00PM-6:00PM Thief of Thieves signing with artist Shawn Martinbrough, writer James Asmus and colorist Felix Serrano
Sunday, October 14th:
11:00AM-12:00 PM Jason Howard signing, artist for Super Dinosaur
3:30PM-5:00PM Robert Kirkman signing, creator/writer of The Walking Dead, Invincible, Super Dinosaur and Thief of Thieves
Hey Skybounders! New York Comic Con was almost 2 weeks ago, and I'm still recovering. As always we had a great time in the Big Apple. The convention was amazingly busy. It was great to see some familiar faces as well as a TON of new ones. We took some photos from the con, but not nearly enough. If you have some pics of Skybound from NYCC, be sure to post them up on Flickr and tag Skybound!
Here are a few pics. More are on our Flickr page!


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At Live Music Management we hold regular DJ auditions in various locales around the UK. These are for our party DJs but also for wedding DJs and mobile discos. We like to see everyone and build up a relationship with the act before we give them a booking. We are constantly on the look out for new talent for night clubs , parties and events and there is rarely a day that passes without someone calling the Live Music Management to see if we have any work for a DJ.
The format for our DJ auditions tends to always be the same. We ask people to turn up and meet with one of our reps and then to perform a twenty minute DJ audition. It's the same format that we have been running for the best part of fifteen years and we know that with this style of audition it is rare that we miss on real talent and it is easy to wheedle out the DJs who will clearly not meet with the standards of Live Music Management.
The DJ auditions usually take place in one of our High Street venues like Walkabout or Bar Risa. Very often they will be run at a time when the venue is closed or quiet. It can be quite an intimidating atmosphere , even for an experienced jock.
Often we are asked in advance how to pass a DJ audition. Many of the DJs auditioning for us have not had to go through this experience with new clients in the past. We had one night club DJ arrogantly tell us that he never did auditions. When he decided to attend the audition it was clear that he was not very experienced and had been bluffing about his abilities.
These are our top tips on How to pass a DJ audition.
1. Be friendly , be dressed appropriate for the venue , be punctual.
2. Check your levels before starting your set. Often DJs will start playing music based on the previous DJs levels which may have been way out. Make sure the mic is not distorting. Make sure the music sounds right. Wander around the venue . Check the volume is okay. Check that the sound is fine.
3. Don't worry too much about repeating a track someone else has played. Play your twenty minutes as if you are the star of the show and it's the heat of the night with a packed dance floor.
4. If it's appropriate to the venue and your style then use the mic (almost all the nights LMM book require mic work ) use it to stamp your authority on the room. Don't talk over every song. Use the mic as if the venue is busy. Incorporate the name of the venue into your speech.
5. Throw in a little set piece mash up or clever mix but don't worry about cramming every trick in the book into twenty minutes. Maybe five minutes of tricks would be perfect.
6. Be confident!
If you would like details of how to audition for Live Music Management then email your details to email@example.com with phone numbers and dates when you are available in the week (ie If you have Saturdays currently available then we will be more interested than if you are just available on Mondays) and don't forget to send your phone number. We are particularly looking for quality London wedding DJs


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NBC's Up All Night should have been a hit. The show came with a strong comedy pedigree: It starred Christina Applegate, Will Arnett and Maya Rudolph and was produced by Saturday Night Live don Lorne Michaels. At the center was what seemed to be a relatable premise for the young adults watching the network's upscale comedies: a hip, young couple adjusts to life with a baby.
But two years after creator Emily Spivey shot the pilot (then called Alpha Mom), Up All Night is all but gone, suffering the death of a thousand tinkers. A heavily touted plan to morph the show into a multi-camera sitcom is now mostly abandoned, and some of the outlandish ideas bandied about for the revamp (including one idea involving rock star...read more
Ahead of several big creative changes behind the scenes, Christina Applegate is leaving Up All Night after two seasons.
"It's been a great experience working on Up All Night, but the show has taken a different creative direction and I decided it was best for me to...read more
Take a trip back in time to where it all began: Chris and Reagan's wedding day! watch
more Jon Pollack Clips & Interviews videos
Determined to deliver some good news in their annual holiday newsletter, the Brinkley family hits the road to show Amy her first real snow.
Take a trip back in time to where it all began: Chris and Reagan's wedding day!
Determined to deliver some good news in their annual holiday newsletter, the Brinkley family hits the road to show Amy her first real snow. Also available on iTunes
After deciding not to elope to Las Vegas at the last second, Reagan and Chris decide to hold a big friends and family wedding. Things don't go quite as they dreamed when big news from Ava and even bigger news from Scott begin to derail the big day before it even starts.
more Jon Pollack On TV videos
more Jon Pollack credits (3 total credits)
As the hilariously unhinged Amy, Mary Elizabeth Ellis puts the "perfect" in Perfect Couples. Tonight, Amy tries to map out a career plan, so we decided it was the perfect time to give Ellis some ... read more
Love is in the air on network TV. From NBC's Perfect Couples to ABC's Happy Endings, each of the big four networks have new romantic comedies to kick off the new year. How to tell the difference between the young love on CBS' Mad Love and Fox's Traffic Light? TVGuide.com has worked up a handy guide to navigate prime time's web of romance. (Just be ready for some TV sitcom déjà vu.)
Olivia Munn: Why I left Attack of the Show!
Perfect Couples (Thursdays at 8:30/7:30c on NBC) Premise: Three very different couples try to figure out the definition of the perfect relationship. You Know Them From: Worst Week's Kyle Bornheimer, FlashForward's Christine Woods, Attack of the Show!'s Olivia Munn and... read more
NBC is capitalizing on its hit The Sing-Off and expanding the show's season finale by 30 minutes.
The network will stretch The Sing-Off's live finale until 10:30/9:30c Monday. The 2½-hour broadcast will be followed by a preview of the comedy... read more
NBC has picked up its sixth new series for the 2010-11 season, the romantic comedy Perfect Couples, the network announced Wednesday.
The show, from executive producers Jon Pollack (30 Rock) and Scott Silveri (Friends), revolves around three very different couples in search of the... read more
You might be also interested in the following websites:


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The savory warmth from maple syrup is the key ingredient to these tasty Maple Walnut Bars. They're made with Duncan Hines Classic Yellow Cake Mix, so they're guaranteed a winner at bake sales, community events, and club gatherings.
- 1 pkg Duncan Hines® Moist Deluxe® Classic Yellow Cake Mix
- 1/3 cup butter or margarine, melted
- 4 large eggs
- 1 1/3 cups Mrs. Butterworth's® Syrup or your favorite maple syrup
- 1/3 cup packed light brown sugar
- 1/2 tsp vanilla extract
- 1 cup chopped walnuts
- Preheat oven to 350 ºF. Grease 13x9-inch pan.
- Reserve 2/3 cup cake mix; set aside. Combine remaining cake mix, melted butter and 1 egg in large bowl. Stir until thoroughly blended. (Mixture will be crumbly.) Press into prepared pan.
- Bake 15 to 20 minutes or until light golden brown.
- Combine reserved cake mix, maple syrup, remaining 3 eggs, sugar and vanilla extract in large mixing bowl. Beat at low speed with electric mixer for 3 minutes. Pour over crust. Sprinkle with walnuts.
- Bake 30 to 35 minutes or until filling is set. Cool completely in pan. Cut into bars. Store in refrigerator.
Please log in or sign up to write a review or discussion.
No Rating
Ceece (1 discussion) on May 18, 2011 at 03:08 PM
Hello there, I am new to the DH forum and to baking. I am interested in making these bars. When the recipe calls for "butter or margarine," is there one that more preferable than the other when baking? Also, would you typically use regular or unsalted butter? Any info or tips would help. Thanks! = )
Comment by: christyrrice (1 discussion) on Jun 16, 2011 at 10:50 AM
I just use the store brand butter, or margarine like Imperial that says "great for baking". Others have too much water content. I use regular butter unless the recipe calls for unsalted.
Comment by: darcy.perreault (no discussions) on Apr 15, 2013 at 02:39 PM
always use butter vs margarine whenever given a choice. The flavor is so much better and use unsalted butter unless otherwise stated.
christyrrice (1 discussion) on May 7, 2011 at 07:08 PM
Try substituting crumbled lean fried bacon for the walnuts. Fabulous!!!
No Rating
SarahsMimi (1 discussion) on Sep 27, 2010 at 09:44 AM
Has anyone made this recipe and put a caramel glaze on top?
rituaneja (3 discussions) on Dec 15, 2009 at 01:39 AM
its yuwwiee and can be stored for the brunch time
lesnounours (1 discussion) on Dec 10, 2009 at 08:06 AM
I did it for my husband's office and they loved it! A few people asked for the recipe.
I did it for my husband's office and they loved it! A few people asked for the recipe.
sugarbaby (1 discussion) on Oct 12, 2009 at 09:10 PM
This recipe is wonderful expecially on a cool or cold day, let it sit for about 30 mins and still warm. I only make it during cool weather but everyone that has tried it has asked for it time and time again and all during the year. It's delicious!!!!
Comment by: PigeonAnnie (no discussions) on Dec 21, 2010 at 11:50 PM
When I made these the first time, I pressed the crumb mixture too hard into the pan before baking and the result was a tough texture. The next time I lightly pressed the dry cake mixture into the pan and it worked fine. I am making them for Charistmas gifts and cutting them into small squares placed on an edible candy plate I make with a mold with a raised leaf design.
Comment by: ANMARIE_WILSON (3 discussions) on Jan 17, 2012 at 10:38 PM
to PigeonAnnie.. please tell us how to make these edible candy plates!!!! I'm excited... I want to try this!


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This year, the focus shifted to California, where an emerging group of community development credit unions (CDCUs), led by Federation board member and Community Trust CU (Modesto) staff member Sandell McLaughlin, have worked with the California and Nevada Credit Union Leagues, credit unions, and regulators to stage one of the best-attended and extensive programs to date.
"As financial literacy becomes ever more important in America, we are collaborating to educate our communities," said McLaughlin, "We are excited to be able to share the ideas from this successful forum with colleagues all over the country in early 2008."
This year's event, titled Financial Literacy Day: Best Practices Forum was held at the Federal Reserve Bank of San Francisco. It drew approximately one hundred people who came to learn about financial education for youth, immigrants, people living with disabilities, the elderly, and the unbanked.
The program was also notable for the broad representation of financial regulators, along with the increasingly important role credit unions have played in financial literacy. "The FDIC loves you," community affairs officer Linda Ortega told the audience, "You guys have the heart" for the work of financial education.
The program also included keynote presentations from the Treasurer for the City and County of San Francisco, José Cisneros, NCUA Board Chairman JoAnn Johnson, and Mission Area FCU Youth Credit Union Program (YCUP) representative Diane Tello.
Treasurer Cisneros spoke about his office's partnership with credit unions in the Bank on San Francisco program. He emphasized that "Establishing a relationship with a financial institution is key – getting people to know that they have a 'true partner' working to make them successful," and that, Federation members Northeast Community FCU and Mission Area FCU "are our experts, our CDCUs."
NCUA Board Chairman Johnson explained that, "We can't be the moral police for how people spend their money… it's about making choices," and that, "CUs have gained the appreciation of the government" for the work they are doing to help people make better choices.
During the event, the Federation also celebrated the 10th Anniversary of Mission Area FCU's YCUP by presenting representatives with a plaque commemorating the milestone.
"Mission Area's YCUP has consistently been one of the Federation's most innovative youth programs," said Federation Executive Director, Cliff Rosenthal, "They continue to push the envelope with their work that touches their entire community."
The Federation has long been a supporter of Youth Credit Union Programs because of the valuable effect they have on their communities and the importance of educating the next generation of credit union leaders. Each year the Federation organizes a youth track during their annual conferences, as well as offering program support to CDCU youth programs nationally.
The day also featured multimedia presentations. The Federation presented its West Coast premiere of "Bridges to the Underserved: Credit Union Partnerships," and Tena Lozano of the California Credit Union League's Richard Myles Johnson Foundation shared excerpts from the Credit Union-supported BizKid$ television series.
"Bridges to the Underserved" is a 17-minute video detailing the Federation's efforts to promote partnerships between large credit unions and CDCUs to better serve low-income communities. It features one of the leading partnerships in the country, between $4-billion Patelco CU and the two aforementioned CDCUs, Mission Area FCU, which serves a predominantly Latino membership, and Northeast Community FCU, whose membership is largely Asian American.
Sponsors for this year's financial literacy day included Patelco CU (San Francisco, CA), Community Trust CU (Modesto, CA), the California and Nevada Credit Union Leagues, and the Bank of America Educational Endowment.


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1. | neeru | ||
Neeru means water adapted from the sanskrit word "neer" meaning water. there is lack of neeru in the deserts.
2. | neeru | ||
A miracle ear for corporate management, incapable of relaying truth. An inciter and a pervert. If you want to get your bosses attention, just nEERU him or her.


text:
I'm Janis Weaver and my passion is networking, connecting people and sharing information/resources, as well as using and promoting SendOutCards.com
"Currently, I'm a marketing distributor for SendOutCards.com, soon to be a Senior Distributor. SOC marries the power of technology to design personalized cards, including photos, with old fashioned snail mail. Send a free card via my website. Enjoy!"
I love Your Stage. Steve Lowell is so knowledgeable when it comes to public speaking and how to get your message "from the page to the Stage". Also Bob Carscadden shares many keen insights and powerful messages about becoming better human beings and kinder to ourselves and others.
Sign in to post a Greeting.
Thanks for your kind words. Betty and I always learn something new everytime we attend and today was no exception. See you next time!


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Route planner from | to | via this address.
Paraje El Cañuelo sn
14546 Santaella
The Hotel Doña Aldonza is situated in the heart of the countryside close to the village of Santaella in the southern province of Cordoba. The hotel is in an ideal position for visiting the many and diverse places of interest in this beautiful part of Spain. These include the major cities of historic importance with their stunning architecture and rich history, to the small picturesque villages with their white walls and pretty squares that are typical of the region.Its location makes it ideal for excursions to the main historical centres of the area owing to the excellent transport links with the cities of Cordoba, Granada, Seville and Malaga and their respective airports as well. It's placed just 12 km. away from the junction.
Number of rooms : 19
Check availability with LateRooms
Access for people with reduced mobility | Pets allowed |
Restaurant | Satellite channels |
Hotel details


text:
Discover the essential elements for successful action learning programs, explore the steps and processes of action learning, and have the opportunity to coach action learning groups. More »
An introduction to the analysis model of Performance DNA, this program is designed to prepare you to conduct a comprehensive analysis of human performance for any position. More »
Learn to apply the ASTD six-step CHANGE model to facilitate change interventions of all types. More »
Develop successful coaching competencies and skills and learn to apply a comprehensive model to individual, team, and organizational coaching initiatives More »
This program demonstrates the behaviors and processes for effective internal consulting, including the actions to take to achieve desired outcomes, establishing goals and managing expectations, guiding clients through the process, building credibility to influence decision-making, and overcoming obstacles and resistance. More »
The complete foundation program for designing outcome-based training, giving participants a competitive advantage when creating learning programs. More »
Learn to develop meaningful and memorable e-learning experiences that motivate learners to change behavior. More »
This dynamic and performance-based program provides multiple techniques for delivering exceptional facilitation. More »
This program is a high-level introduction of the Human Performance Improvement (HPI) process and principles. More »
Be introduced to a proven approach to improving performance and learn how to use the Human Performance Improvement (HPI) process to help your stakeholders create bottom-line results. More »


text:
Ink & Toner Finder:
Item: 901719 Model: 378SM-J8000
8 oz., 50/Pack
Currently Out of Stock.
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8 oz. hot cup. 50 cups per pack. High quality and dependable. Contains 10% post consumer recycled fiber
10 oz. hot cups 1,000 cups per pack Single polylined For use with hot beverages SOLO® Symphony® Paper Hot Cups provide an ...
These efficient cups feature thin, yet durable walls, a rolled rim for a superior lid fit and full print graphics to showcase ...


text:
Case Studies in Abnormal Psychology, 8th EditionNovember 2008, ©2009
Here is a sample of what people are saying about Case Studies in Abnormal Psychology, Eighth Edition:
"The case studies book was by far the most interesting text book I have had for any class. The case studies helped me get a better idea of the disorders through the people that are affected by them."
"I like the case studies a lot because they were real examples and illustrated the concepts for diseases very well."
"I loved the case studies book and felt that it added a lot to the textbook and my understanding of each disorder."
2. Panic Disorder with Agoraphobia.
3. Posttraumatic Stress Disorder: Rape Trauma.
4. Social Phobia.
5. Hypertension in an African American Man.
6. Dissociative Identity Disorder: Multiple Personality.
7. Major Depressive Disorder.
8. Bipolar Mood Disorder.
9. Somatization Disorder.
10. Schizophrenia: Paranoid Type.
11. Psychotic Disorder (NOS), Substance Dependence, and Violence.
12. Alcohol Dependence.
13. Sexual Dysfunction: Female Orgasmic Disorder and Premature Ejaculation.
14. Paraphilias: Exhibitionism and Frotteurism.
15. Gender Identity Disorder: Transsexualism.
16. Eating Disorder: Anorexia Nervosa.
17. Eating Disorder: Bulimia Nervosa.
18. Paranoid Personality Disorder.
19. Borderline Personality Disorder.
20. Antisocial Personality Disorder: Psychopathy.
21. Autistic Disorder.
22. Attention-Deficit/Hyperactivity Disorder.
23. Oppositional Defiant Disorder.
- One new case has been added describing a childhood disorder. This case provides important coverage of the successful use of treatment procedures combining behavioral and family systems perspectives.
- Critical Thinking Questions: Featured at the end of each chapter and designed to draw the reader's attention to challenging and potentially controversial issues raised by the cases in the text.
- Strong coverage of cultural, ethnic, gender, and women's issues.
- Best known for its in-depth discussion sections.
- Includes a number of transcripts of therapy sessions, giving students a realistic view of psychotherapy.
- Excellent balance in various perspectives and treatments.
- Comprehensive and scholarly.


text:
Bryant's 36 leads Lakers out of rut
Posted: December 17, 2012 at 2 a.m.
Kobe Bryant and the Los Angeles Lakers are winning again. It's just a two-game streak, but it's still a turnaround from their struggling ways of late.
This story is only available from our archives.
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"My mother-in-law was making this salad when I got married 48 years ago. It has always been on our holiday table." - by Lenna
Adjust Servings
Original recipe yields 12 servings
- In a small bowl, combine the ground cranberries and sugar. Set mixture aside for at least 3 hours.
- In a large bowl, whip cream and stir in quartered marshmallows. Set aside for 3 hours.
- After 3 hours fold the berry mixture into the whipped cream. Then fold in the crushed pineapple. Let set for several hours or overnight for flavors to blend.
Amount Per Serving (12 total)
- Calories
- 313 cal
- 16%
- Fat
- 14.8 g
- 23%
- Carbs
- 46.5 g
- 15%
Based on a 2,000 calorie diet
Share It
Reviews (34)
Rate This Recipe"This is a recipe that my grandmother has made for 40+ years. Here are some helpful hints to make it even better. Start in the morning of the day before you want to serve. Crush the cranberries and mix..." See more with 1 1/2 cups sugar (my grandmother uses 2!! which is a bit much so I use 1 1/2) Mix together and let it rest all day. Drain the juice out at the end of the day and put it back in the fridge. Day of: Drain again, add marshmallows, a big can of crushed pineapple, and 2 cups red seedless grapes, halved. Then right before you want to serve whip the cream and add 1 cup whipped cream to the salad!! This makes it aaaaaaa-mazing!!"
"My Women's Club made this to serve at a luncheon given for a Holiday House Tour. We made the following changes in the recipe to save a little work and expense, and found that the result did not suffer..." See more at all. We used 1 10 oz. bag mini marshmellows per recipe and 4 c. coolwhip instead of whipped cream. The recipe doubles, or triples well. We used a 1/2 c. scoop to serve and the salad kept its shape nicely."
"I've never had raw cranberries and was skeptical but this recipe is very yummy tasting. Everyone really enjoyed it at Thanksgiving last year and it's been requested for this year as well. Very tart an..." See mored sweet at the same time. I'll make this any day instead of boring jello salad."
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Tablets, smartphones and TVs upstage PCs at CES
PC makers made fewer product announcements than in past years
IDG News Service - PCs were upstaged by tablets, smartphones and TVs at this year's International CES show, with some companies maintaining a smaller presence or holding back product announcements for a later date.
There were fewer product announcements from PC makers compared to previous years, with some companies waiting for the GSMA Mobile World Congress in Barcelona Feb. 25-28.
"I think the timing of CES was bad this year for the PC cycle, and several did mention MWC as a venue for their next announcements," said Roger Kay, president of Endpoint Technologies Associates, who attended the show.
Asus canceled a scheduled CES press conference, delaying product announcements to MWC. Acer was virtually absent at this year's show after it held a press conference last year to announce ultrabooks. Hewlett-Packard, the world's top PC maker, announced Pavilion Sleekbook laptops ahead of CES and showed those at small media events on the sidelines. Dell showed off incremental upgrades to its Inspiron laptops and Latitude tablet, and also announced a thin client for businesses called Project Ophelia, which failed to draw a lot of interest.
"Major industry and trade shows continue to be focal points and bring together customers, partners and influencers, and as a result many vendors opt to use these events as platforms for announcements," said a Dell spokeswoman Ellen Murphy in an email. She declined to comment on Dell's plans for MWC.
Lenovo maintained high visibility with new products like the IdeaCentre Horizon table PC getting attention. As in past years, the Chinese company rented out the Aquaknox bar at the Venetian, but it did not hold a press conference for mainstream media. Lenovo was thrilled with the response it got at CES, a company spokeswoman said in an email.
Tablets with Windows 8 were introduced by small companies like Vizio, Panasonic and Razer, while Android tablets were shown by Archos, Coby, Polaroid and RCA. Intel, Advanced Micro Devices, Nvidia and Qualcomm also took center stage, announcing chips that could be used in future smartphones, tablets and PCs.
The shift at CES from a focus on PCs to mobile devices reflects the overall market shift, with PCs increasingly taking a back seat to tablets and smartphones, which are finding wider use for basic computing, Web browsing, video and email. Smart TVs are taking on some of the functionality of PCs, allowing users to browse the Web and stream videos from websites like Netflix.
The PC market is weak with traditional laptops and desktops no longer the centerpiece of IT, said IDC research director David Daoud, who was not surprised that the PC presence was subdued at CES. The PC market is in the process of a reboot, Daoud said. New thin-and-light laptop designs are being developed with tablet-like features such as touchscreens and detachable hinges, which could attract a whole new set of buyers.
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