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Capecitabine belongs to a class of drugs called antimetabolites. It interferes with the growth of cancer cells. Capecitabine is available as tablets that are taken by mouth (oral).
By: | Reference Healthwise Staff | Last Revised: September 5, 2012 |
Medical Review: | Reference E. Gregory Thompson, MD - Internal Medicine
Reference Kenneth Bark, MD - Surgery, Colon and Rectal |
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Portion of Route 9 will close Wednesday morningStaff Report | March 19,2013MARLBORO- State Police will close a portion of Route 9 Wednesday morning.
At 9 a.m., Route 9 will be closed at the intersection of Adams Cross Road, which is between Auger Hole Road and Butterfield Road and east of Hogback Mountain. The only detours available will be on dirt roads unsuitable for heavy commercial traffic.
The road will be closed for one or two hours, said police, who since this afternoon have urged tractor-trailer drivers to travel south into Massachusetts to Interstate 90.MORE IN This Just InPolice investigate Full StoryWoman answers to theft charges Full StoryLocal ham radio operators will have a "field day" this weekend. Full Story -
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Report: Sixers trying to trade Iguodala for Bynum
News blogs, sports blogs, entertainment blogs, and more from Philly.com, The Philadelphia Inquirer and the Philadelphia Daily News.
Report: Sixers trying to trade Iguodala for Bynum
John Mitchell, Inquirer Staff Writer
The Sixers are involved in trade talks concerning a deal that could see them deal all-star forward and Olympian Andre Iguodala and receive Los Angeles Lakers center Andrew Bynum.
According to a report that first appeared on Yahoo!, the Sixers have been engaged for a few days in talks about a possible four team deal that also includes the Denver Nuggets and the Orlando Magic.
Reached for comment on Wednesday, Sixers CEO and minority owner Adam Aron, as is the team's policy, did not comment on the talks.
The potential blockbuster deal would send Iguodala to the Nuggets. Orlando center Dwight Howard and Denver forward All Harington would be shipped to the Lakers, who would send Bynum to Philadelphia. Orlando would receive forward Pau Gasol from the Lakers and guard Arron Afflalo from Denver. Orlando guard Jason Richardson has also been mentioned prominently as part of the deal.
Bynum, 24, is 7-0, 285 pounds and regarded as probably the second-best center in the league behind Howard. Last season, Bynum averaged 18.7 points, 11.8 rebounds and almost two blocks per game.
Entering the final year of his contract, Bynum is scheduled to make slightly less than $16.5 million this season. It would be to the Sixers' benefit to know if Bynum would be willing to sign a long-term deal with the team, otherwise he could wind up being a half-season rental and the Sixers could possibly find themselves trying to deal the center next season at the trade deadline.
The good news for the Sixers, if this were to be the case, is that there would almost certainly be a healthy market for Bynum, who has had his own set of health issues in the past.
Bynum has had surgery on both his knees. Taken by the Lakers with the 10th pick in the 2005 draft, Bynum has played all 82 games just once in his career. Although he appeared in 60 of 66 possible games this past season, Bynum appeared in just 204 of a possible 328 games from the 2007-08 season through the 2010-11 season.
- astroqueen0
- Iron Giant
- camasbud
- john ullman
Oh yeah…..
GO EAGLES!!! connorjr- Njtod10
- rzzzzz
- hardball
Already paying Hawes too much. Then to pay Bynum too??
Makes no sense.
You'll appreciate AI2 when he's gone.
True the Sixers still need a hungry rebounder and paint scorer so why trade for Bynum when you need a 24yr old Duncan/Blake like every other team?
I'd take Zach Randolph before Bynum.
Still it's hard to give up AI2 - a 2/3 who can defend, pass, and glue the team together without knowing if Evan Turner is going to be the goods. ThePhillyDave- sgamble077
- HDemetriou
- JimG
- Wow, really delved into the burning questions in this article. Thanks for all the insight??? I challenge this writer to just once, just one time, provide some information that everybody didn't already know
- jojotr44
- brownrice


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Wednesday, October 13, 2010
Oliver to Europe
8 comments:
- AnonymousOctober 14, 2010 at 7:41 AM
welcome Oliver Lafayette the N1 club with bes fans PARTIZAN BELGRADE SAMO PARTIZAN I MAJKA SRBIJA
ReplyDelete - AnonymousOctober 14, 2010 at 9:33 AM
OR he could play for a legitimate team in Europe, get payed 10x more AND be scouted more by NBA scouts than he could in the D-League rather than play for a ridiculous team called the "Mad Ants"
ReplyDelete - AnonymousOctober 14, 2010 at 1:12 PM
Finally!!! Partizan got excellent player, and still looking for position 4 player. When they complete their roster, I am sure that they will have good team for this season in euroleague.
http://www.worldofbasketball.org - AnonymousOctober 15, 2010 at 7:20 AM
Do you worry about Oliver, No European team or NbaD team has given as much players in the NBA as Partizan did and they have always been the trademark of the country which was multiple European and World basketball champion.Thanks for Oliver and and good luck to you further competition
ReplyDelete - AnonymousOctober 16, 2010 at 7:34 PM
Partizan has a player by the name of Jan Vesely who will be scouted by every NBA decision marker this year. How many of those guys will watch a D-League game live? 5? 10? I am not talking about scouts, but actual decision makers. Seems Oliver is smarter than you are giving him credit for...
ReplyDelete - AnonymousOctober 20, 2010 at 9:08 PM
Jeff is right in the sense that going to Europe will hurt Oliver's chances in many senses of NBA action, particularly this year.
You really can't do a 10-day with a guy playing internationally. That said, for a kid like him, who had a circuitous route to get to where he is today, you can't blame him for taking money. Nothing has ever been sure for him, he's always been an underdog. The opportunity to guarantee himself some wealth (that may be half or more of the NBA minimum) was probably too great to pass up.
Yea, he'll be scouted over there... by international NBA scouts, not the personnel staff in the U.S. If he plays well he might be able to get himself a partially or fully guaranteed offer in the NBA next year, but he's basically putting the NBA thing on hold.
A lot of times this works for players and Europe proves more lucrative (look at guys like Mike Batiste or J.R. Holden). Sometimes this approach isn't always the best - no league in the world has the upside to make a ton of money as the NBA does. With the NBA, the right opportunity can eventually lead to a free agent contract that is multiple times what guys like Bastiste and Holden are making. Or it just leads to another opportunity (playing time) that lands such a contract.
It's not clear what the right decision are in these instances - it comes down to the personal decision of the player. How long he is willing to play for very little money (when he may have nothing) in order to pursue an NBA career vs. taking deals that may be less than an NBA minimum contract, but still nonetheless lucrative.
For a lot of guys, once you are a pro, it's about earning as much as you can over your career (playing days are short), and from a risk-reward standpoint, just going to Europe and building a career. In the States, success is binary - either you are or you aren't - there is no between. So it often the value of being able to achieve a dream that keeps one chasing the NBA, not necessarily money.


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Store > KBORIBVR
KBORIBVR 0 remaining Orimono - Lucky Cats & Geisha - Lacquer Red/GoldUS $8.95
White, Dk Lilac, Turquoise, Black, Cherry, Sun Gold, Persimmon, Pecan, Lacquer Red, Gold MetallicThis colorful Japanese print features fans with bright Geishas, Lucky Cat figurines, fish and toys set over a stylized, floral, medallion ground. Etched in gold metallic and with lots of visual interest this traditionally inspired print offers a playful touch of contemporary design. Fans are about 5 5/8", with gold metallic, from the 'Orimono II' collection by Kona Bay Fabrics.
Quantity: yardsMinimum 0.5 yard;increments of 0.25 yard


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Order within 77 hours 1 minutefor Delivery on Wednesday 29th May
£160 Cashback. The long-awaited Canon 5D Mark III follows on from the highly specified Canon 5D Mark II but with the addition of a few new, much needed enhancements. The 5D Mark III is aimed at the semi-pro and professional level photographers who desire a lightweight, weather-proof construction, outstanding image quality and impressive levels of speed. The Canon 5D Mark III features a high-resolution 22.3 CMOS sensor and Canon's latest powerful DIGIC 5+ processor to ensure a lightning fast frame rate of 6 frames per second. A newly developed 61-point AF system (41 cross-types) and an impressive expandable ISO range from 50-102,400 ensures both static and fast moving subjects can be captured, even in dimly lit environments. Not only is it capable of producing exceptional stills, the Canon 5D Mark III can also record Full HD 1080p movies, offering full manual control and stereo sound, and the 3.5mm mic socket and headphone socket allows audio monitoring while recording. More
November 2012 - I am a full time professional wedding photographer. I shoot with a combination of cameras, notably the Fuji X-Pro1 and the 5D range of cameras from Canon. The 5D2 was the first full frame body I owned and I ended up working my way through three of them. So, when the 5D3 was announced I was really quite excited about it. Read Kevin's review of the Canon 5D MK III... »
March 2012 - "Today, after three years of rumour and speculation Canon has officially announced the Canon 5D Mark III. Building on the 5D Mark II the new camera (we're told it's not going to replace the mark II), the 5D Mark III closes the gap between the 5D and 1D series cameras...Read More »
Flash control Without the Canon 600EX-RT flashgun (or E3-RT Transmitter) installed on the camera you can't wirelessly control another flash. To control a slave from the 5D Mark III, or any other EOS camera for that matter, you will need a master of some sort on the hot shoe (either a 600EX-RT or a ST-E3). Full support of the 600EX with the 5D MK III means that you get full control of the flash using the LCD. And full support of AF assist – the 600EX has support for all the focus points of the 5D MK III. The 5D MK III does not feature a built-in flash.
We caught up with David Parry on the Canon Stand at Focus 2012 to find out a little more on the new Canon 5D Mark III.
Full-frame 22.3-megapixel sensor Capture high-quality images that are full of detail with a 22.3 megapixel CMOS sensorand DIGIC 5+ image processor. Colours are bright but natural, and fine detail is preserved even in dark shadow areas and bright highlights.
High-quality performance, even in low light The EOS 5D Mark III delivers superb picture quality whatever the lighting conditions. Keep shooting hand-held even after the sun goes down, thanks to an ISO 100– 25,600 sensitivity range (extendable from ISO 50 - 102,400).
61-point wide-area autofocus Focus quickly and accurately, even on offcentre subjects, with a 61 point wide-areaautofocus system. 41 cross-type points(five of which are extra sensitive double crosstype) ensure highly accurate tracking of moving objects.
High-speed continuous shooting Keep up with the action at 6 frames per second, recording up to 16,270 continuous JPEG images to a UDMA mode 7 card in a single burst.
Get creative With the new Creative Photo button you have quick and easy access to HDR image creation, Multiple Exposure and 7 pre-set Picture Styles with the ability to create 3 more user defined styles.
Full-HD video with manual control Enjoy high quality Full HD video at 1080p resolution. Use manual controls and Canon's comprehensive EF Lens range to achieve cinematic visual effects.
Great quality sound Give your video footage the soundtrack it deserves. The EOS 5D Mark III records digital stereo sound at 48KHz and offers manual control over audio level. A standard 3.5mm mic socket enables the use of thirdparty microphones; a headphone socket permits audio monitoring while recording.
In-camera editing functions Begin your digital editing workflow before you arrive back home. Rate your images on a scale of one to five and compare two images simultaneously on screen. Use in-camera Raw processing to explore creative possibilities – such as black & white conversion and retrospective white balance.
Built to go anywhere A magnesium chassis provides strength and durability without adding weight. Weather sealing offers protection against dust and moisture.
The Canon Sample images can be found here on the Canon website.
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1D light?
By The Dig
from Manchester
About Me Photo Enthusiast
Comments about Canon EOS 5D Mark III Digital SLR Camera Body:
22MP is really all you need unless you do billboards all the time!Useful new features, (haven't played with in camera HDR yet).Undoubtedly does the job but having a 1D III, and not deep enough pockets for a 1DX, I would have preferred 1D body type with "proper" batteries and it's superior weatherproofing. Had to get the battery grip which part resolves the power issue and gives portrait controls "back". Understand, though, that this combination makes it the identical weight of a 1D which won't suit everyone.Overall an outstanding piece of kit but for rough weather and high frame rate need, (& knocking in tent pegs), my 1D III will still be in the bag.
Great camera
By D_Gillan
from Perth
About Me Semi-pro Photographer
Great for both stills and video..
I love my 5D mark iii
By Pati
from Wales
I find the 5D mark iii fantastic for theatre performance photography.It's ability to record in low light is particularly impressive.I also like the dual card slots for memory.
Great Camera
By Timmer
from Plymouth
See all my reviews
Lovely upgrade from the 7D, full frame is great, fully utilise those L series EF lenses.Love the focus options.Dual card is nice. Even in camera HDR!
Excellent Camera
By Russ
from Banchory, Scotland
Replacing an aging Canon D60 which always struggled with focus speed and low light performance; the 5D is a breath of fresh air.All of the controls are readily accessible and the menu driven controls through the LCD are intuitive and easy to read. Even the full automatic modes are very well set up- but can seduce you into using them too much.Possibly a little to expensive for a low use amateur like myself, however I am delighted with what I have bought.Works fantastically with the 70 -200mm IS2.8 L IS lens I bought to go with it. Great combination!
(1 of 1 customers found this review helpful)
Upgrade is worth every penny!
By Creative capture- weddings
from Reading
About Me Pro Photographer
I was happy with my Canon 5D Mark ii until i got this camera! The focusing system is amazing! With the canon 5D ii, i just didn't trust AI servo it struggled to keep up with even slow moving subjects so i never used it. This the 5D iii never misses in AI servo mode i can't rate it enough!Image quality is great even at high ISO's but i wouldn't say it was miles better than the 5D ii which was already really good.My photography partner still has the 5D ii and at a recent virtually no light event, he had to manual focus...in the dark! Whilst my 5D iii coped really well on auto focus! One thing that no one ever seems to talk about in reviews is the auto ISO in manual mode. On the Canon 5D ii it was all but useless only going up to 400 ISO...no good to anyone! However i find it quite useful at times with the 5D iii. I like to work in manual at all times, however sometimes it is nice to give up and let the camera decide and for me that is never the shutter speed or aperture. The only one small down side to this feature is that you can't adjust the exposure compensation as you can do with semi auto modes. So in practice you still have no choice whether to under or over expose whilst using the auto ISO in manual, to me that is slightly daft. Lets hope that next upgrade takes this on board, then it would be the perfect little feature!
By john at sunset
from sutton coldfield
Great for wildlife in low light situations. Brilliant for landscapes, particularly with built in HDR capability.The most exiting piece of new kit I have ever bought.
Glad I finally weakened and brought one
By Terry f2.8
from Newmarket Suffolk
I looked at this camera for ages before I finally took the plunge, probably if I'm honest because of the initial outlay but I have to say now I've got it I think it's really impressive, easy to use and navigate. Now I wonder why it took me so long, certainly enthused my desire to achieve.To date I don't have any con's
So far so good
By tartanbriefs
from DUNFERMLINE
Seems to be performing well in its first few months out on the road. I'm enjoying the sharpness of the images and as a DSLR video Pro I'm loving the headphones socket.
Outstanding performance
By DMC
The 5D Mark III is without doubt a significant upgrade from the Mark II. I have been shooting with a Mark II and a 7D for a few years and the Mark III is a massive improvement in all the key areas - namely - image quality, high ISO performance, auto focus and metering. It also has many small improvements - larger screen, dual card slots, 6fps, faster processing, improved weather sealing and 100% view finder coverage. These all add up to a truly outstanding camera. For wedding photography and photojournalism the 5D Mark III is an absolute must.
Please Note: Used items are not eligible for Finance, Promotional or Cashback Offers.
Included Accessories: Eyecup Eg, Wide strap EW-EOS EOS 5D Mark III, Interface cable IFC-200U, Stereo AV cable AVC-DC400ST, Battery Pack LP-E6, Battery charger LC-E6, Instruction book, Warranty card


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text: Are you looking to move into a neighborhood in lancaster County, but know nothing about it? Before you buy a home in lancaster County, South Carolina or find a new lancaster County new homes, do a neighborhood search first. Here you can find statistics on lancaster County, sc neighborhood housing, cost of living, weather, economy, household demographics and lancaster County schools to help you decide which neighborhood is right for you. lancaster County, South Carolina neighborhood information made easy with AOL Real Estate. Start browsing lancaster County cities/towns today by clicking one of the links below.


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Activision's Social Media Manager Dan Amrich has announced that beginning today the Blur multiplayer PS3 demo is live on PlayStation Network.
To quote: Today, the PlayStation 3 demo of http://blurgame.com/home became available in the PlayStation Store - and you know what comes standard?
Pools of lightning bolts, explosive mines, bursts of nitro speed, and big glowing red balls of homing-missile danger. This is the kind of arcade-style combat racing that gets my motor running.
Oh, and the mileage is excellent - I've been playing http://www.bizarrecreations.com/games/blur/ for weeks now and I'm still not bored.
The Blur multiplayer demo gives you a pretty sizeable chunk of what the game has to offer. A dozen real-world cars, including I'll-never-own-it-but-I-can-drool rides like the Lotus Exige Cup 260 and Ford GT.
Six tracks in two gameplay modes and seven mods that let you tweak the game mechanics to match your style of play all eight of the chaotic power-ups, and the ability to boast about your skills to friends on the PlayStation Network with a single button press. (The full retail version also lets you brag on Facebook and Twitter.)
I have hosted http://oneofswords.com/2010/06/playing-with-swords-blur-ps3-64-2/ on multiple continents, and have more in the works. I shared some of my http://oneofswords.com/2010/05/five-tips-for-blur-dominance/ for success (and people used them against me).
I even had Gareth Wilson, lead designer from developer Bizarre Creations, http://oneofswords.com/2010/05/one-of-swords-podcast-018-swords-and-beheadings/ to explain some of the choices that went into the game and wound up getting him to reveal a key to success that I've been personally milking all the way to the finish line.
If you haven't tried Blur yet, it's understandable - heaven knows there are plenty of options when it comes to quality PS3 racing games. But the demo's free for the taking as of today, so check it out and let me know if you feel what I feel when you play it. And know that I'm serious when I say I will see you on the track...
More PlayStation 3 News...
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text:
Birth of the Clinic
Author:Foucault, Michel
Publisher: Routledge
Summary: Michel Foucault, one of the most influential thinkers of recent times, invites the reader to analyse the methods of observation that underpinned the origins of modern medical techniques and to uncover new layers of significance.
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AstraZeneca selects location for new global R&D centre and corporate headquarters in Cambridge, UK Move brings AstraZeneca's small molecule and...
New Survey Reveals One in Five Women Have Information They Keep Secret from their Doctors Even When Medicines Have Already Been Tried, Candid...
New Data Showed Livalo (Pitavastatin) 4 Mg Had Neutral Effects on Fasting Serum Glucose and Hba1c Levels in HIV-Infected Adults With Dyslipidemia...
The patients died 3-4 days after receiving an appropriate dose of the drug
You know you have a popular brand when scam artists are using it to bolster their schemes. But Eli Lilly, which says scamsters are using its well-...
Healthcare Communications Agencies & Marketing Services Directory
Qualified Clinical Research Organizations Directory
Technical Resources International Inc. - Bethesda MD (2 months 3 weeks ago)
Founded in 1979, Technical Resources International, Inc. (TRI) provides a unique range of support services in the areas of Communications, Health and Information Technology to both private industry and government agency clients. TRI is currently seeking a Quality Assurance (QA) Compliance Specialist to join our...
You know you have a popular brand when scam artists are using it to bolster their schemes. But Eli Lilly, which says scamsters are using its well-known moniker and also the Elanco Animal Health name, is not amused. The drugmaker has notified authorities that scam artists are using it as a foil to bilk people out of money after telling them they won a foreign lottery or may be able to get a job at... Lilly.
Here is how Lilly describes them: "In the first scam, victims have reported receiving a letter from a foreign lottery sweepstakes organization indicating that the victims have won a large cash award. Included with the letter is a fraudulent check drawn on an account in the name of Lilly or Elanco. The check is supposedly to cover lottery fees, taxes or other expenses. Victims are instructed to contact a claims agent, and are then told to deposit the check into their bank account and transmit an amount of money back to the lottery organization or to a broker.
"In the second scam, victims have reported being contacted through email or other online methods regarding potential employment opportunities with Lilly based on the victims' submission of information to certain resume and career websites. Through online dialogue, the victims are told they are either being considered for or are being offered employment with Lilly. At some point in the dialogue, the victims are told to expect a check to be delivered to them which they are to deposit into their bank account and then use the funds to purchase 'working materials' from an online vendor."
It is not clear why a scamster would choose the Lilly or Elanco names, but presumably, not everyone can be expected to think twice about the name on a check. Despite the numerous layoffs that have taken place at Lilly, the drugmaker does hire selectively and those in need of a job should not be faulted for pursuing a lead, however tenuous it may appear. But receiving checks is generally not part of the job-hunting process, as far as we can recall.
In any event, Lilly has issued a statement saying "Lilly (LLY) and Elanco have no connection to any foreign lottery organizations and do not conduct the type of online recruiting described by the job-seeking victims of the scam. The activities described in these scams are completely fraudulent and are in no way affiliated with, or sponsored by, Eli Lilly and Company or its affiliates or subsidiaries." The lawyers have spoken.
In the latest flap over Johnson & Johnson product recalls, the Chinese government has taken the health care giant to task for its quality control procedures and, more specifically, allegedly failing to withdraw some products that have been pulled from other markets, according to reports.
Last week, the China Food and Drug Administration met with J&J officials and issued a statement urging improvements in quality control. The agency also vowed to strengthen oversight to ensure timely recalls and pledged to crack down on companies that conduct late or secretive recalls, Global Times writes.
What prompted the meeting? The missive came shortly after a newsletter in Beijing called Health Times reported that J&J conducted at least 51 global product recalls since April 2005, but 48 of those products were not recalled from the mainland Chinese market. In other words, a double standard exists.
The report noted that, last April, J&J recalled nearly 1.7 million bottles of Children's Tylenol made and sold in South Korea due to a high level of acetaminophen, which may cause liver damage (back story). The J&J unit in Shanghai insisted the bottles were not sold in the mainland. But Health Times disputed the contention.
The newsletter also pointed to a decision last December by a J&J domestic unit to halt sales of the Velcade injection after an order from the CFDA, but Health Times contended the product had already been recalled in the US, UK and Japan a year earlier.
The meeting marked the first time the CFDA held talks with a multinational company over quality problems, indicating that China's watchdog is increasing its attention to drug safety, Liu Baocheng, director of the Center for International Business Ethics at the University of International Business and Economics, told the Global Times.
As for J&J, the healthcare giant issued a statement to Asian media saying its mainland Chinese subsidiaries have reported all product recalls conducted in the mainland in accordance with CFDA rules. And a spokesman in the US sent us this: "Johnson & Johnson has a strong commitment to delivering quality products to Chinese consumers as well as our customers all over the world.
"We have one global quality policy that applies worldwide to all of our companies, and when any of our companies initiates a product recall for quality reasons, we work with health authorities to determine the appropriate course of action in the best interest of patients and consumers."
[UPDATE: And he adds that "there may be instances when quality actions initiated in other parts of the world do not affect a specific country because the products in question are not sold there or the facilities where quality matters have arisen do not manufacture products for that country. When any of our companies initiates a product recall for quality reasons, we work with health authorities to determine the appropriate course of action in the best interest of patients and consumers."]
Nonetheless, J&J may be suffering from some of the consumer confidence issues seen not long ago in the US. A survey by Eastmoney.com last week found that 91.4 percent of 4,652 respondents would no longer buy any J&J products, Global Times writes. Why? Well, 34 cited continuous quality problems in recent years, while 50 percent pointed to a different attitude toward the mainland market for recalls.
As we have noted previously, over the past three years, J&J (JNJ) has experienced an outsized list of manufacturing problems that have led to recalls of Tylenol, Motrin, Rolaids, Sudafed and Benadryl; K-Y Jelly; Acuvue contact...
Waste not, want not? Given the state of the US health care system – prescriptions, procedures and hospital emergency room visits abound – would anyone be surprised to hear that lots of money is wasted? But did you know that some $213 billion – which equals 8 percent of all health care expenditures - is spent unnecessarily due to various faux pas involving prescription medicines?
These include medication errors; patients who fail to take their medicines; the abuse and misuse of antibiotics; insufficient use of lower-cost generics; delays in providing medication when it would be most effective, and mismanaged 'polypharmacy' in people - especially those 60 years and older - who take numerous medicines on a daily or regular basis and can suffer adverse events as a result of drug interactions.
"Drugs are often not used optimally, resulting in significant unnecessary health system spending and patient burdens. Those avoidable costs could pay for the healthcare of more than 24 million currently uninsured US citizens," says Murray Aitken, executive director at the IMS Institute for Healthcare Informatics, which conducted the study. "We would say all of those could be avoided if medicines were used more responsibly."
The findings come, of course, as a national debate intensifies over rising health care costs – including those for prescription drugs – and pressure is mounting to find ways to lower those expenses. And so, as IMS explains, more efficient use of medicines – as well as decision-making surrounding treatment – could move the needle in the right direction.
Breaking it down, IMS found that delays in applying diagnosis and treatment – what it calls evidence-based practice - leads to $40 billion in annual avoidable costs. The study examined four diseases – hepatitis C, coronary heart disease, atrial fibrillation and diabetes (you can obtain the report here).
Misuse of antibiotics contributes an estimated $34 billion each year in avoidable inpatient care costs and another $1 billion spent on about 31 million inappropriate prescriptions dispensed annually. Direct costs are incurred through longer medical treatment, expensive second- and third-hand antibiotics, and screening and tests for detecting and prevent the spread of resistant bacterial strains.
Patient non-adherence led to $105 billion in avoidable costs, based on examining six disease categories – high cholesterol, high blood pressure, HIV, osteoporosis, and congestive heart failure. At $44 billion, high chosleterol was the disease with the highest avoidable cost.
Moreover, Aitken notes that the estimates are actually conservative because these analyses include only certain diseases categories, albeit some that constitute a large amount of drug utilization.
Looked at another way, if medications were utilized appropriately, IMS estimates that $100 million in hospital costs; $45 billion in outpatient costs; $22 billion in pharmacy costs and $46 billion in emergency room visits could be saved.
If there is a bright side, Aitken notes signs of progress. For instance, the proportion of patients diagnosed with the common cold or flu and receiving antibiotics has fallen from 20 percent in 2007 to 6 percent last year. And generic utilization is at about 95 percent.
pill pic thx to anolobb on flickr
In a setback to an important joint venture between Bristol-Myers Squibb (BMY) and AstraZeneca (AZN), the top-line results of a large, late-stage study of their Onglyza diabetes drug failed to show superiority in reducing cardiovascular deaths, heart attacks and strokes compared to a placebo in Type 2 diabetes patients with cardiovascular risk factors (read this).
At the same time, the findings of the so-called SAVOR study, which examined more than 16,000 patients, also indicated that Onglyza did not cause cardiovascular harm, which is a key FDA litmus test for diabetes pills since heart risks are a common concern for diabetics. But the outcome suggests that wider use of the drug and other DPP-4 medicines, such as Januvia, which is sold by Merck (MRK), is unlikely to occur.
"Ruling out CV harm is good, of course, but it had been hoped… that positive SAVOR results would supercharge the DPP-4 inhibitor class to which Onglyza belongs," writes Sanford Bernstein analyst Tim Anderson in an investor note. "Therefore, SAVOR will be viewed as more of a missed opportunity to boost Onglyza and the overall class."
Onglyza, which generated $709 million in sales last year, is a crucial component in the joint venture, but sales have recently stalled, reflecting questions over the safety of these drugs and a few other diabetes medicines thanks to a pair of studies raising concerns over the potential for causal links to pancreatitis and pancreatic cancer (see this and this). And a watchdog group found a high rate of adverse events for these illnesses (read more here).
In response to the ruckus, the NIH last week held a two-day workshop to review the issue and while the outcome was inconclusive, the FDA hinted that additional studies may be sought. Meanwhile, the American Diabetes Association is now asking drugmakers to provide patient-level data for an independent review (lots more here).
The effect of these developments and the ensuing publicity is causing uncertainty about the extent to which physicians and patients will embrace the medicines, along with the related class of GLP-1 inhibitors, which includes Novo Nordisk's Victoza. As ISI Group analyst Mark Schoenebaum points out, doctors are expected to "read across" the SAVOR results to other DPP-4 inhibitors, although he believes the results were not unexpected and so should not change prescribing habits.
Just the same, the brief statement issued by Bristol-Myers Squibb and AstraZeneca did not include any safety information, which will not be known until full results are reported at the annual meeting of the European Society of Cardiology later this year. Consequently, Onglyza is likely to remain in a holding pattern, at best, for the time being. Meanwhile, Anderson is holding his Onglyza forecasts steady at about $900 million this year, while he sees Januvia reaching about $6.1 billion.
thumbs down pic thx to italianvoice on flickr
In a few months, we will know exactly how much Teva Pharmaceutical compensates ceo Jeremy Levin. The drugmaker has agreed to settle a class-action lawsuit filed last fall by a pair of Israeli academics, who challenged Teva over its failure to disclose compensation given executives. Teva claimed to adhere to Israeli law, which permits companies with dual stock exchange listings to report salaries on a group basis, rather than disclose individual sums. But the professors, who are also Teva shareholders, filed a class-action lawsuit arguing the drugmaker failed to meet basic disclosure requirements and investors were shortchanged.
In a brief statement the drugmaker says the move is being made to provide "greater transparency" and that the first such disclosure will be found in its 2013 annual report, which will be released in early 2014. The drugmaker is also reimbursing the professors $1.1 million in legal fees and related expenses, as well as $200,000 in compensation that will be split evenly (here is the statement and here is the lawsuit filed last November).
"Our effort has been successful," say Sharon Hannes, a law professor at Tel Aviv University and Ehud Kamar, who is a law professor at the University of Southern California, in a statement sent to us. "Thanks to our suit, Teva will change its compensation disclosure practices in a significant way. We expect other dual-listed companies to follow Teva and also disclose executive compensation on an individual basis. This should begin a new chapter in the history of Israel's capital markets, one in which shareholders of all public companies can monitor executive pay and ensure that its level and structure are appropriate."
As we noted previously, US law requires info about executive and director pay from domestic and foreign companies that issue securities, but with one exception - compensation can be disclosed on a group basis when laws of a home country do not require reporting on an individual basis. The professors argued that, under US law, the default position is disclosure on an individual basis, and this applies to Teva, unless the drugmaker is exempt under Israeli law or can cite some other reason.
They maintained Teva could not prove exemption from individual disclosure under Israeli law since this is the default requirement under Israeli disclosure regulations. The drugmaker changed its reporting practices for executives more than a decade ago after Israeli law was changed to allow dual-listed companies to use financial statements that were acceptable under US law.
In the latest move by regulators to clamp down on so-called pay-to-delay deals, the European Commission has fined Lundbeck and four other drugmakers for reaching agreements to block entry of generic versions of the best-selling Celexa antidepressant. Lundbeck was fined $125.6 million, while the others - including Ranbaxy Laboratories - paid a total of nearly $70 million.
After the basic patent that Lundbeck held on the molecule had expired, the drugmaker only retained a number of related process patents that provided limited protection. And so, Lundbeck struck deals in 2002 with generic rivals to refrain from selling copycat versions in return for "substantial payments and other inducements amounting to tens of million of euros," according to the EC.
The regulator cited internal documents that refer to a "club" being formed and "a pile of $$$" to be shared, and charged that Lundbeck paid "significant lump sums," purchased stock from the generic drugmakers for the "sole purpose of destroying it," and offered guaranteed profits in a distribution agreement.
"It is unacceptable that a company pays off its competitors to stay out of its market and delay the entry of cheaper medicines," says EC vp Joaquin Almunia in a statement. "Agreements of this type directly harm patients and national health systems, which are already under tight budgetary constraints. The commission will not tolerate such anti-competitive practices."
The move comes amid increased scrutiny of these deals on both sides of the Atlantic and also marks the first time that the EC, which has been investigating such settlements for several years, has levied a fine. Over the past year, the regulator has twice issued what it calls a 'statement of objection' to other drugmakers (see here and here).
And earlier this week, the US Supreme Court ruled that drugmakers can face lawsuits over these deals, although they should not necessarily be assumed to be illegal. The decision largely vindicated the argument by the US Federal Trade Commission that such settlements are anti-competitive and cost US consumers some $3.5 billion annually (more here).
However, the court noted that there may be justifications for payments. "Where a reverse payment reflects traditional settlement considerations, such as avoided litigation costs or fair value for services," the court wrote, "there is not the same concern that a patentee is using its monopoly profits to avoid the risk of patent invalidation or a finding of noninfringement."
In a strongly worded statement, Lundbeck took exception to the EC conclusion and seemed to be making this argument. The drugmaker insisted it "acted transparently and in good faith trying to protect its patents," and vowed to appeal the fine. Lundbeck "strongly disagrees with the commission's decision... Any setttlement agreements involving a transfer of value from an originator to a generic company is a restriction of competition and the value transfer reflects an understanding that the patent is invalid or weak. The approach is erroneous... Patent settlement agreements are efficiency enhancing and...
Good morning, everyone, and how are you today? Another busy day is unfolding here on the Pharmalot corporate campus, where the maintence crew is tending to a number of important projects. As for us, we are quaffing the usual cup of stimulation - we are still enjoying Hazelnut Cinnamon Creme - and invite you to join us with a cup of your own. Meanwhile, we also have much to do. So here are some tidbits. Have a great day and feel free to drop us a line at firstname.lastname@example.com when something interesting arises...
Indian Regulator To Review J&J Appeal On License Cancellation (Business Standard)
Pfizer Settles With Canadians Over Neurontin Side Effects (The Toronto Sun)
Astellas Looks To Sell Dermatology Assets (Reuters)
AMA House Overrides Its Council And Calls Obestity A Disease (MedPage Today)
Glaxo May Sell Bloodthinners To Aspen Pharmacare (Pharma Times)
Bayer To Add Jobs At Animal Health Plant In Missouri (St. Joseph News-Press)
Protalix Signs Supply Deal For Gaucher Drug With Brazil (Associated Press)
German Regulator Rebuffs Sanofi Diabetes Drug (BioCentury)
Indonesia To Raise Drug Prices By 10 Percent (The Jakarta Post)
Probe Into Thailand Regulator Joined By Union (Bangkok Post)
EDITOR'S NOTE: Please check this post for additional stories during the day
steaming coffee pix thx to dleggett on flickr
Last week, the NIH ran a workshop to examine the safety of several widely used diabetes drugs called GLP-1 inhibitors and whether a definitive link can be established to acute pancreatitis and pancreatic cancer, which were the subject of recent studies that generated considerable controversy. The outcome was inconclusive, but the FDA may want further studies. Meanwhile, the American Diabetes Association called for drugmakers that sell these meds to release patient-level data that can be used for an independent review (back stories here, here and here). Whether the drugmakers - Merck, Bristol-Myers Squibb, AstraZeneca, Eli Lilly, Novo Nordisk and Boehringer Ingelheim – will comply remains to be seen. With the exception of GlaxoSmithKline, the pharmaceutical industry has resisted releasing such data over concerns that proprietary information will be compromised. But ADA chief medical officer and chief scientific officer Robert Ratner believes they are now on the spot. We spoke with him about this decision…
Pharmalot: Three months ago, when one study was first released, the ADA issued a statement that played down or at least sought to allay concerns. Now you want patient-level data. I don't know if you would consider this an about face, but it's certainly a change in tone. What happened?
Ratner: Science is an iterative process and the way science unfolds, observations are made and hypotheses are tested and then it goes through peer reviews and is challenged. It takes a long time to arrive at the truth and the goal is always to provide accurate information to scientists, clinicians and, ultimately, to patients. As evidence accumulates, we need to deal with it and we deal with it in a whole variety of ways. And part of it is to critically look at data and ask if it is accurate and appropriate. Has a study been done with sufficient rigor? And how do we interpret the data? And that was part of the statement following (the first study). The statement a week ago is in recognition of continued press and controversy over the role of pancreatitis and pancreatic carcinoma. There's an enormous amount of opinions flying around. Our goal is to develop a system in which we can take a look at the data that are available.
Pharmalot: Of course, patient level data is not something most drugmakers seem to want to provide. What are your expectations about receiving that kind of data?
Ratner: We want maximal transparency and a maximal degree of data to make rational judgments about the veracity of the data. I'm very encouraged that we've had public commitments about working with us in this regard. You're absolutely right - we're asking a great deal and part of it is to maximize public confidence in what is found. We've not heard from some companies, but they are considering a response, but all involved have expressed support for what we're trying to do. We simply have to wait and see to the extent to which we're going to be able to do all this.
Pharmalot: How hard do you think you'll have to work to get this data?
Ratner: I think we're going to get it. In conversations with industry representative, the questions we're discussing are the format of data, transmission process of data, whether data is going to be sent to us or supplied through a distributed data network. We're getting down to that level of detail… There's a huge problem with looking at mean data from a whole variety of different...
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Retiring captain Stephen Craigan is expected to return to the Motherwell team for the Clydesdale Bank Premier League clash against Dundee United.
The 35-year-old announced his retirement on Tuesday and is expected to lead the team out for the final time.
The Fir Park match will be a double celebration, both of Craigan's 15 years at Fir Park and the team's Champions League qualification following their third-place finish in the Clydesdale Bank Premier League.
Craigan won 54 caps for Northern Ireland and played in two cup finals for Motherwell as well as being part of three European campaigns.
The defender, whose 378 Motherwell appearances were interrupted by a three-year spell at Partick Thistle, said: "I'm excited and I'm content with the decision I've made. It has been in the back of my mind for a few months.
"Once that thought comes in your head it's hard to get rid of. If you're having a bad day at training or struggling to get back from injury or just feeling a bit low, that thought keeps coming back.
"The emotional side I had to put to the back of my mind and try to make a logical decision that is best for me. But this weekend is going to be great. It's everything I have worked hard for, to play football for 18 years.
"It's good that it's a celebration because we are in the Champions League and have done as well as we ever have done in the SPL. That plays a little bit of a part in your decision as well. I wouldn't have liked to have finished seventh or eight in the league and say goodbye in front of 2,000 people. Ticket prices are down to £5 so hopefully it will be a good day all round."
Motherwell could rest some players who have been playing with knocks after securing third place.
Michael Higdon has been suffering from a back injury and is also one booking away from suspension so is likely to miss out.
United have doubts over several defenders with Robbie Neilson (ankle), Gavin Gunning (shoulder) and Barry Douglas (knock) are all unlikely to be risked.
Striker Milos Lacny (knee) remains on the sidelines.
The Tangerines clinched a Europa League spot thanks to last weekend's home win over champions Celticl.
United have the advantage of going in at a later stage of this season's Europa League qualifiers unlike last season when they faced Polish team Slask Wroclaw in early July.
But boss Peter Houston said: "It's not really something we've thought about that much.
"It's another great achievement by everyone to get into Europe for the third season running.
"It will probably help to have that bit more time to prepare this time round as last season's start was very early.
"However, we still have some league business to attend to this weekend when we go to Motherwell."
Motherwell squad: Randolph, Hateley, Hammell, Clancy, Hutchinson, Jennings, Lasley, Law, Humphrey, Murphy, McHugh, Craigan, Forbes, Ojamaa, Carswell, Daley, Saunders, Hollis.
Dundee United squad: Pernis, Dillon, Kenneth, Gunning, Neilson, Dixon, Flood, Rankin, Robertson, Mackay-Steven, Russell, Daly, Ryan, Armstrong, Watson, Dow, Swanson, Douglas, Banks


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Liposuction: Q&A
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Numbness After Lipo?
I had lipo 4 months ago and the spot under my belly button is still numb. Most of the other numbness is gone but this particular spot did not gain any...
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Numbing Solution in Fixing Dents and Lumps from Liposuction?
About 2 years ago, I had Liposuction done on my thighs and flanks. I ended up with a few dents and lumps. Recently, I went to a different doctor for a...
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Swollen and Numb After Laser Lipo
This is my 3rd time having laser lipo done on my waist and upper arms. The diff is, in the past, i did incured a great amount of pain but this time, i...
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Hardness and Numbness 16 Weeks After Liposuction
16 weeks after liposuction, my stomach still feels hard and numb, and there are soft lumps on my flanks, is this normal? My stomach continues to feel...
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Numbness in my Right Arm After Liposuction
Three weeks ago I had undergone a lipo on multipple areas such as arms,back, stomach, and around the waist with the following fat graftiong to the...
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Periodic Numbness and Shooting Pain 7 Weeks After Lipo. Is This Normal?
Seems to be healing well, except every hour or so I get a shooting pain in 2 areas of my abdomen. Both areas as still a bit swollen. THose are the...
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Fat in Private Area Would Prevent Reaching Orgasm?
I was shocked to hear that from my plastic surgeon , i looked it up cant find anyhing ... How true is that , is it risky to do lipo in my private area...
7 doctor answers
Normal for Lumps and Numbness to Remain 16 Weeks After Lipo?
Hard stomach, numbness and hard and soft lumps remain 16 weeks after lipo. Is it normal to have stomach remain hard and numb and for soft and hard...
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Discomfort 10 Months After Liposuction
I had liposuction on my abdomen about 10 months ago. It has been feeling great. However, the last few weeks, it has started to feel uncomfortable –...
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Upper Thight Numbness 10 Months After TT, Will It Affect Lipo of Thigh?
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Worked great up in the snow! Kept him warm, dry and happy all day long! He looks super cute while riding a snowmobile with his daddy too!… - HOLLY, 12/10/10 Coos Bay, OR
I bought 2 of these jackets, one for my 2 year old and one for my 4 year old. We live in Southern Connecticut and the winters get pretty cold, so I'm expecting a lot out of t… - Melissa, 11/23/11 Stamford, CT
My son who is 2 yrs 6 months but thin as a rail loves the jacket but it is too cold without multiple layers. On the positive side, I can fit a t-shirt, sweatshirt and a down v… - Tak, 01/11/13 NYC
Bought this for my son. He is 3 1/2. Kinda short and 4t was perfect, so maybe size up if you have a big kid. No pockets on reversible side, but its a really god fit and he sta… - Chris, 10/01/12 Lansing
I moved to Michigan having no experience living in a snowy weather. This is the first jacket I bought for my toddler. At school the kids played in the snow 1 to 2 hrs a day.… - GABRIELA, 11/01/10
I would have to rate this jacket a 10 for warmth, and a 3 for style. However I am a loyal fan of patagonia products and I have to say all of their stuff rocks!… - andrea, 09/30/10
This jacket has a feminine slim fit which I love! It's a great snow jacket but it runs big and comes with it's own size chart [ different than Moosejaw's size guide]: Size… - Malissa, 12/14/12
This jacket also has a slim flattering cut . The exposed metal zippers give this girly jacket a bit of an edge. Also this piece will not let you down in the warmth department.… - hechun, 04/26/12
I was hesitant to buy this product at first b/c not having seen it in person, I was afraid it might be too bulky/thick for our 3 year old kiddo. But it's not bulky at all and… - Kay, 02/19/12 Boston
So I decided to get coordinating coats for my two boys. I was excited to see the coats since they both looked nice and was even happier when I noticed that the toddler version… - Casey, 12/12/12 Chesterfield
My little one refuses to keep on her socks and shoes--even in winter! We needed something warm that would cover her hands and feet that she couldn't remove and this was the a… - jaimy, 01/01/12 virginia
My nearly two year old got this coat a few months ago and so far it has kept her nice and toasty! Last night she had it on for about 4 hours in temps in the 30s and still fai… - Jess, 12/19/11 Tampa
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Read more ›Diky Frankces
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Longtime Publisher Jim Adolph Rejoins Source Interlink Media Staff
Former Top Fuel Funny Car Driver takes over American Motorcycle Group
EL SEGUNDO, Calif. (December 1, 2011) – This week, Source Interlink Media welcomed back Jim Adolph as publisher of the American Motorcycle Group, which comprises Hot Bike, Hot Bike Baggers and Street Choppers magazines. Adolph previously served as publisher of Car Craft magazine for the company from the mid-'80's through early '90's and oversaw the launch of Chevy High Performance magazine and published Corvette Fever magazine.
Aside from his role as a magazine publisher, Adolph was a licensed Top Fuel Funny Car driver, competing professionally from the early '70s all the way into the early '90s.
His career as a driver lent itself perfectly to Adolph's pursuits with the company; Car Craft magazine served as a drag racing publication for many years, instituting the 35-year Car Craft All-Star Drag Racing Program. Adolph was also the publisher of Drag Racing magazine in the late '80s.
While his new role at Source Interlink Media may seem like a departure from his background in automobiles, Adolph is an avid motorcycle enthusiast and says he couldn't be more excited. In fact, during his days as publisher of Car Craft and Drag Racing, he was asked to help launch HOT ROD Harleys, the company's first V-Twin publication.
"Given my history with the company, I couldn't be happier to be rejoining the staff at Source Interlink Media," said Adolph. "Not only do I have a lot of friends and colleagues that are still here in the office, but now I also get to fuel a great passion of mine – motorcycles. I am certainly looking forward to this new position and it's great to be back."
About Source Interlink Companies:
Source Interlink Companies (http://www.sourceinterlink.com/) is the leading publisher of magazines and on-line content for enthusiast audiences, as well as a leading sales and service distributor of magazines and provider of related in-store services across North America. Through its sales and services initiatives, the Company is able to optimize its media properties through its vertically integrated distribution assets. Source Interlink creates content for more than 70 publications, 90 websites, events, television, and radio. Its portfolio includes many respected brands such as Motor Trend, Automobile, Hot Rod, Automotive.com, Surfer and Intellichoice.


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Larry Kline
Havre Daily News
CHINOOK - State District Judge John McKeon on Tuesday denied a new trial for convicted killer Laurence Dean Jackson Jr., whom a Missoula jury 18 months ago found guilty in the shooting death of one Blaine County sheriff's deputy and the wounding of another.
In an order filed Tuesday morning in state District Court in Chinook, McKeon wrote that evidence and argument presented by defense
attorneys did not merit a new trial, based on the standards of state law and U.S. Supreme Court case law.
Jackson, 28, is serving two life terms, plus 100 years, for the slaying of deputy Joshua Rutherford and the wounding of fellow deputy Loren Janis on the night of May 29, 2003.
Havre attorney Bob Peterson today said he and Helena attorney Ed Sheehy will move forward with their appeal, filed in state Supreme Court on March 7. The higher court had sent the case back to McKeon for a ruling on the defense lawyers' motion for a new trial.
"Now the whole case will be in the lap of the Supreme Court," Peterson said.
Rutherford and Janis were responding to a domestic disturbance call involving Jackson. During the November 2004 trial prosecutors argued that Jackson wrestled Rutherford's service weapon from the deputy and, in a rapid succession of shots, used it to fatally shoot Rutherford and wound Janis.
In two motions and a March 23 court session, defense attorneys Bob Peterson of Havre and Ed Sheehy Jr. of Helena argued that a statement written by Janis and read at Jackson's sentencing hearing in November contained new evidence that should have been considered by jurors.
In the statement, Janis said he "started to believe" rumors that he was to blame for Rutherford's death.
Conversations with a close friend, himself a former Blaine County sheriff's deputy, and "numerous hours" of counseling alleviated Janis' self-blame and made him realize that Jackson was to blame for the slaying, he wrote.
The defense lawyers initially said the statement was the first they'd heard about Janis' conversations with a counselor. They maintained that the former deputy's feelings of self-blame could have been explored during the trial, had they been aware of the content of those counseling sessions.
During the March 23 hearing, Peterson said he could not in his files find a document, sent by prosecutors, that included the counselor's name amongst a list of people Janis had talked with about the shooting. Sheehy was able to find it in his files, and the attorneys said they had not talked about the list of names.
McKeon agreed with Blaine County Attorney Yvonne Laird and special prosecutor Carlo Canty, who argued that they were under no requirement to uncover the content of Janis' conversations with his counselor. Furthermore, the judge wrote, defense attorneys had adequate opportunity to do their own investigation into Janis' counseling sessions.
"Failure of defense counsel to maintain an orderly file or to appropriately communicate with each other does not excuse the lack of diligence," McKeon wrote.
The judge also wrote that "a reasonable probability does not exist that the outcome of the proceedings would have been different" if the content of Janis' counseling sessions had been discussed at trial.
He disagreed with the defense's assertion that the prosecution's case rested solely on Janis, and cited other witnesses and testimony presented at the trial.
McKeon also wrote that defense attorneys attempted to show Janis' self-doubt during the trial by calling an Indian Health Service nurse to the stand. The woman testified that she heard Janis questioning himself over whether he had shot Rutherford.
"Indeed, (the nurse's testimony) related to events at the hospital soon after the shooting whereas Janis' victim statement is nearly 18 months later," McKeon wrote. "Further, the context of Janis' statement 18 months later is one of a victim responding to rumors. ... Taken as a whole, the confidence of the jury verdicts rendered herein has not been undermined."


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Home > Tuition & Financial Aid
All student aid recipients are responsible for managing their funding on eLion. Students can review current information on student loans and other aid by visiting www.elion.psu.edu and clicking on the Student Aid Summary from the left-hand menu.
Contact Us
firstname.lastname@example.com 610-648-3238 610-725-5381 fax
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About Your Smart Kitchen
Quality products and tools for quality conscious chefs at a reasonable price.
We are a small business, starting in 2007, with the intent of locating and selling some of the best cooking products in the world for your use and benefit. We hope to become your source for both quality products and information regarding cooking and kitchens
We are starting with some impressive product lines and will be adding additional lines from time to time. And while we do not strive to be the biggest retailer in this area, we will endeavor to be the best.
Through relationships with premier vendors and suppliers, we provide state-of-the-art fulfillment and responsive customer service. YourSMARTKitchen.com makes it easy for quality oriented, brand focused, and value-conscious shoppers to find the merchandise the love and prices they will love as well.
Need that special sauce pan, or roasting pan, or possibly, a unique serving or mixing bowl?
We are searching the world for these and other tools for your kitchen. We look for complementary products as well, trying to anticipate your needs.
Terry Retter
Your SMART Kitchen


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When it comes to classy, sophisticated and comfortable dress materials, few types of fabric can rival the qualities of linen. Apart from the regular linen suits, shirts and jackets for men, various types of stylish women's and kids' dresses are also made from this fabric. If you are an admirer of linen, you will surely find the following facts about it interesting:
- Source – Linen is obtained from the flax fibre. Since the fabric is available naturally, its extraction does not cause any adverse environmental effects.
- Initial usage – The usage of linen fibre can be traced back to nearly 4500 B.C. Ancient Egyptian mummies were generally wrapped up in linen, to keep them intact over centuries.
- Quality and softness – Unlike most other textile fibres, linen dresses actually become softer and more comfortable over time. They get wrinkled rather easily, but the sheer pleasure of putting on linen dresses goes on increasing.
- Anti-allergic nature – Linen cloth is completely anti-allergic in nature, and do not cause any type of skin irritations whatsoever. Hence, they are also often used for making underwear and lingerie items.
- Resists static electricity – The presence of flax fibre in linen is instrumental in keeping the levels of static electricity in check. Even blended linen outfits help in keeping down static electricity.
- Linen products 'breathe' – Moisture can easily pass through the permeable surface of linen. Since adequate moisture is always retained, linen fibre always feels cool and comfortable.
- Keeps body temperature lower – Speaking of comfort, did you know that wearing linen clothes can keep your body temperature around 4 degrees (Centigrade) lower than what it is, when you wear clothes of other textile fibres? Perspiration levels remain low, minimizing the chances of wearer discomfort.
- Linen resists harmful solar radiations – You can stay safe from the harmful gamma radiations, when you put on linen dresses. This, in turn, makes them ideal to be worn on bright, sunny days. When you buy linen clothes from renowned stores, like any of the outlets of Linen Club, you can rest assured that the material will have this feature.
- Usage in other household supplies – Linen is also often used for making table-cloths, bedcovers, and other useful pieces of household cloth. That's right – it is not only an apparel fabric!
- Durability and strength – Linen cloth easily scores over other popular textile fibres, like cotton and silk, as far as durability and longevity is concerned. In fact, linen is considered to be the strongest vegetable fibre ever.
- Linen clothes help to sleep well – The bodily cells receive a soothing effect, when you don linen nightwear. The same goes, when you lie down on linen bedsheets. The result? Better, more sound and more refreshing sleep!
- Use in American currency notes – The US treasury also uses linen, in its dollar notes. Each dollar note is made of paper that has one-quarter of linen content.
- Linen keeps out dust, dirt and toxic chemicals – When you wear linen clothes, you are not likely to get affected by external polluting agents. What's more, linen cloth can be easily cleaned too – making their maintenance over a long time, a clinch.
- Recyclable in nature – The linen fabric does not degrade the environment in any way. It can be easily recycled and reused, underlining their eco-friendly nature.
At Linen Club, linen is sourced from the flax fibre of the finest quality. You can discover the entire range of linen products, at any of its outlets across India.
Didn't these facts intrigue you just a little bit more about linen?


text: I'm American and it will be my first time going to a convention in Italy. I don't what to expect. Even with a bablefish translation, I'm at a loss to all that will be there. Will I see a lot of cosplay there in general? Will I be ok asking a cosplayer if I can take their picture in English or should I learn the phrase in Italian? Anything I should know? Thanks Whose going? Are you cosplaying? If so, what as?


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Robert Parrish was an Academy Award-winning film editor who also directed and acted in movies. As a child he appeared in films during the early 1930s, such as City Lights by Charles Chaplin and Lewis Milestone's All Quiet on the Western Front. As an editor he won an Academy Award for Body and Soul, the 1947 Robert Rossen film that starred John Garfield as a money-grubbing... See full bio » Born:in Columbus, Georgia, USADied:(age 79) in Southampton, Long Island, New York, USA |
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Internet: | Wired Internet, Wi-Fi Internet connection |
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Important information & conditions: | Unless otherwise indicated, the charges below are not included in the overall room price. If not included in the overall room price, they will be charged by the property at check-in or check-out. Charges can vary, for example, based on length of stay or the room you book. This property told us they will charge you for the following:A tax is imposed by the city: CHF 3.50 per person, per night. This tax does not apply to children under 13 years of age. We have included all charges provided to us by the property. However, charges can vary, for example, based on length of stay or the room you book. - The following fees and deposits are charged by the property at time of service, check-in, or check-out. Breakfast fee: CHF 22 per person (approximately) Rollaway bed fee: CHF 35 per night The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change. |
Cancellation policy: | You can change or cancel this deal free of charge up to 24 hours before your check-in date. Please take into account that the check-in date starts at 00:00 (local time). - A credit card number is required to confirm the booking. - In case of cancellation, 24 hours before arrival day or in case of no- show, one night-stay per room will be charged on your credit card. - Exchange rates for information only. - Payment due upon departure. - Please do not hesitate to contact us, We are always on hand to assist with your enquiry. firstname.lastname@example.com |
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In the end, it is not our products that matter, but rather what they can achieve in your specific area of application. Here, you will find the challenges and topics that are currently keeping us busy as well as examples of cases that we have already solved successfully.
We at Leuze electronic are the sensor people because we are the specialists in efficient sensor solutions. Why? It's the identity that we embody and the standards we hold to our work.
All peripheral devices – such as sensors, protective switches and cameras – are not worth much without networking to the fieldbus or a control unit. Depending on device type and area of application, our modular interfacing units offer variable interfaces that enable simple connection of the identification devices directly to the fieldbus and thus ensure simple integration of new devices in the system.
Terminal box for BCL 300i/301i with KB301.
Connector unit for BCL 21/22, BCL 31/32, VR 2300, RF ident.
The MA 21 modular connector unit is used to connect Leuze identification systems (IDS) to an RS 232 interface.
Connector unit for daisy chain connections.
Network master with connection options for scanners of the BCL 40 and BCL 80 family.
Fieldbus gateways for field use for connecting bar code readers and identification systems.
Connector unit for easy connection of the BCL 8.
Point-to-point multiNet slave for the BCL 90 product family for easy wiring and configuration.
Connector unit for BCL 22 and BCL 32 with parameter memory
Connector unit for BPS 37


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Moving From API Area to API Stack
by Kin Lane on 01/18/2013Finding APIs that compliment your API, and talking about the mutual benefits is nothing new. When I worked with the print API Mimeo, I would write code that used Mimeo API in conjunction with Box API or Dropbox API. Mashing up or bundling your APIs with other complimentary service can really help, when you are trying to explain the value your API delivers.
I'm beginning to see patterns of even deeper integration and partnerships between APIs emerge--where one API provider will resell the API of another provider. APIs partnering with other APIs isn't that new, but reselling of each others API services to their developers is a fairly new concept, providing a potential new wholesale channel for API providers.
One recent example of this is in a recent partnership between Singly and Cloudmine. Cloudmine is a BaaS provider, and Singly is provider of personal and social data via aggregate APIs. With the reseller approach, Cloudmine developers get a vastly improved stack to develop against, with Cloudmine providing all the essential BaaS tools developers are growing accustomed to, while also having access to 30+ social, personal and other aggregate API services provide by Singly.
The goal of this new approach is to provide developers with the most meaningful stack possible, in a single developer area. A MMS API provider like Mogreet could in theory, to better serve their developers, bundle image APIs like Flickr, Instagram and Facebook from Singly into their API area--providing a more robust stack to their developers who are building media enabled mobile apps.
Now developers don't have to traverse to each API area on their own. APIs can mashup, bundle and develop a stack, which includes their own APIs, but might also have APIs from potentially several other API providers. Obviously there are lots of details to work out around authentication, pricing, etc., but the potential is obvious.
I'm also talking with a linguistics API provider in Europe, and learning more about their partner program, which would allow for 3rd party API providers to submit APIs and sell alongside their own linguistics API. Opening up their API stack for new opportunities and innovation from 3rd party linguistics API providers--in languages, formats they wouldn't have resources to do themselves.
As the number of APIs are growing, and we are seeing APIs aggregate via providers like Singly and through BaaS providers like Cloudmine, I think we'll see individual APIs become more portable, allowing them to be assembled into meaningful API stacks for developers.
Aggregate, Box, CloudMine, Dropbox, Mimeo, Resellers, Singly |
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