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Mutations in STRA6 Cause a Broad Spectrum of Malformations Including Anophthalmia, Congenital Heart Defects, Diaphragmatic Hernia, Alveolar Capillary Dysplasia, Lung Hypoplasia, and Mental Retardation The American Journal of Human Genetics, Volume 80, Issue 3, 1 March 2007, Pages 550-560 Francesca Pasutto, Heinrich Sticht, Gerhard Hammersen, Gabriele Gillessen-Kaesbach, David R. FitzPatrick, Gudrun Nürnberg, Frank Brasch, Heidemarie Schirmer-Zimmermann, John L. Tolmie, David Chitayat, Gunnar Houge, Lorena Fernández-Martínez, Sarah Keating, Geert Mortier, Raoul C.M. Hennekam, Axel von der Wense, Anne Slavotinek, Peter Meinecke, Pierre Bitoun, Christian Becker, Peter Nürnberg, André Reis and Anita Rauch Abstract We observed two unrelated consanguineous families with malformation syndromes sharing anophthalmia and distinct eyebrows as common signs, but differing for alveolar capillary dysplasia or complex congenital heart defect in one and diaphragmatic hernia in the other family. Homozygosity mapping revealed linkage to a common locus on chromosome 15, and pathogenic homozygous mutations were identified in STRA6, a member of a large group of "stimulated by retinoic acid" genes encoding novel transmembrane proteins, transcription factors, and secreted signaling molecules or proteins of largely unknown function. Subsequently, homozygous STRA6 mutations were also demonstrated in 3 of 13 patients chosen on the basis of significant phenotypic overlap to the original cases. While a homozygous deletion generating a premature stop codon (p.G50AfsX22) led to absence of the immunoreactive protein in patient's fibroblast culture, structural analysis of three missense mutations (P90L, P293L, and T321P) suggested significant effects on the geometry of the loops connecting the transmembrane helices of STRA6. Two further variations in the C-terminus (T644M and R655C) alter specific functional sites, an SH2-binding motif and a phosphorylation site, respectively. STRA6 mutations thus define a pleiotropic malformation syndrome representing the first human phenotype associated with mutations in a gene from the "STRA" group. Abstract | Full Text | PDF (1273 kb) |
Mutations in the SPARC-Related Modular Calcium-Binding Protein 1 Gene, SMOC1, Cause Waardenburg Anophthalmia Syndrome The American Journal of Human Genetics, Volume 88, Issue 1, 7 January 2011, Pages 92-98 Hana Abouzeid, Gaëlle Boisset, Tatiana Favez, Mohamed Youssef, Iman Marzouk, Nihal Shakankiry, Nader Bayoumi, Patrick Descombes, Céline Agosti, Francis L. Munier and Daniel F. Schorderet Abstract Waardenburg anophthalmia syndrome, also known as microphthalmia with limb anomalies, ophthalmoacromelic syndrome, and anophthalmia-syndactyly, is a rare autosomal-recessive developmental disorder that has been mapped to 10p11.23. Here we show that this disease is heterogeneous by reporting on a consanguineous family, not linked to the 10p11.23 locus, whose two affected children have a homozygous mutation in SMOC1. Knockdown experiments of the zebrafish smoc1 revealed that smoc1 is important in eye development and that it is expressed in many organs, including brain and somites. Abstract | Full Text | PDF (814 kb) |
Heterozygous Mutations of OTX2 Cause Severe Ocular Malformations The American Journal of Human Genetics, Volume 76, Issue 6, 1 June 2005, Pages 1008-1022 Nicola K. Ragge, Alison G. Brown, Charlotte M. Poloschek, Birgit Lorenz, R. Alex Henderson, Michael P. Clarke, Isabelle Russell-Eggitt, Alistair Fielder, Dianne Gerrelli, Juan Pedro Martinez-Barbera, Piers Ruddle, Jane Hurst, J. Richard O. Collin, Alison Salt, Simon T. Cooper, Pamela J. Thompson, Sanjay M. Sisodiya, Kathleen A. Williamson, David R. FitzPatrick, Veronica van Heyningen and Isabel M. Hanson Abstract Major malformations of the human eye, including microphthalmia and anophthalmia, are examples of phenotypes that recur in families yet often show no clear Mendelian inheritance pattern. Defining loci by mapping is therefore rarely feasible. Using a candidate-gene approach, we have identified heterozygous coding-region changes in the homeobox gene OTX2 in eight families with ocular malformations. The expression pattern of OTX2 in human embryos is consistent with the eye phenotypes observed in the patients, which range from bilateral anophthalmia to retinal defects resembling Leber congenital amaurosis and pigmentary retinopathy. Magnetic resonance imaging scans revealed defects of the optic nerve, optic chiasm, and, in some cases, brain. In two families, the mutations appear to have occurred de novo in severely affected offspring, and, in two other families, the mutations have been inherited from a gonosomal mosaic parent. Data from these four families support a simple model in which OTX2 heterozygous loss-of-function mutations cause ocular malformations. Four additional families display complex inheritance patterns, suggesting that OTX2 mutations alone may not lead to consistent phenotypes. The high incidence of mosaicism and the reduced penetrance have implications for genetic counseling. Abstract | Full Text | PDF (7699 kb) |
Copyright © 2007 The American Society of Human Genetics All rights reserved.
The American Journal of Human Genetics, Volume 80, Issue 6, 1179-1187, 1 June 2007
Christelle Golzio, Jelena Martinovic-Bouriel, Sophie Thomas, Soumaya Mougou-Zrelli, Bettina Grattagliano-Bessières, Maryse Bonnière, Sophie Delahayed, Arnold Munnich, Férechté Encha-Razavi, Stanislas Lyonnet, Michel Vekemans, Tania Attié-Bitach and Heather C. Etcheversf, ,
a INSERM U781 Paris
b Université René Descartes-Paris 5 Paris
c Assistance Publique–Hôpitaux de Paris Departments of Genetics Paris
d Obstetrics Paris
e Hôpital Necker-Enfants Malades, and Institut de Puériculture Department of Fetal Pathology Paris
f INSERM U563, Hôpital Purpan, Toulouse France
Retinoic acid (RA) is a potent teratogen in all vertebrates when tight homeostatic controls on its endogenous dose, location, or timing are perturbed during early embryogenesis. STRA6 encodes an integral cell-membrane protein that favors RA uptake from soluble retinol-binding protein; its transcription is directly regulated by RA levels. Molecular analysis of STRA6 was undertaken in two human fetuses from consanguineous families we previously described with Matthew-Wood syndrome in a context of severe microphthalmia, pulmonary agenesis, bilateral diaphragmatic eventration, duodenal stenosis, pancreatic malformations, and intrauterine growth retardation. The fetuses had either a homozygous insertion/deletion in exon 2 or a homozygous insertion in exon 7 predicting a premature stop codon in STRA6 transcripts. Five other fetuses presenting at least one of the two major signs of clinical anophthalmia or pulmonary hypoplasia with at least one of the two associated signs of diaphragmatic closure defect or cardiopathy had no STRA6 mutations. These findings suggest a molecular basis for the prenatal manifestations of Matthew-Wood syndrome and suggest that phenotypic overlap with other associations may be due to genetic heterogeneity of elements common to the RA- and fibroblast growth factor–signaling cascades.


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The Supreme Court decision on Kiobel v. Royal Dutch Petroleum Co. seemed to deal a blow to foreign victims of foreign human rights abusers who wished to the Alien Tort Statute to sue their abusers in U.S. courts. But the decision might be a blessing in disguise. The ATS never proved that useful in advancing human rights worldwide, and by slamming the door on it, the Supreme Court has pushed the human rights movement to focus on using other tools.
The case against him may be phony, but Alexei Navalny, the Russian blogger and opposition activist, faces long odds in his trial, which begins Wednesday. When Putin cannot co-opt his enemies, it seems, he has other means of crushing them.
The Obama administration has bolstered the International Criminal Court in an effort to prevent atrocities worldwide. Still, Congressional opposition and developments in conflicts abroad might make it hard for Washington to continue to cooperate with the court.
Kirby Dick's documentary The Invisible War has brought long-overdue attention to the problem of sexual assault in the armed forces. Unfortunately, however, the film gives short shrift to two of the major groups of victims -- men and women of color -- which reinforces common myths about rape and makes addressing the problem all the more difficult.
This week, the U.S. Supreme Court dealt a blow to foreign victims of foreign human rights abusers who wish to use U.S. courts to sue their abusers. As a top legal scholar and federal judge wrote in this article--which Justice Stephen Breyer cited in his opinion--such lawsuits offered victims some measure of solace and gave substance to underenforced human rights laws.
In November, former Brazilian President Luiz Inacio Lula da Silva's closest adviser was sentenced to ten years in jail for corruption. Now, the highest court seems determined to go after Lula himself. Whatever the final result, the judges' campaign has convinced Brazil's taxpaying middle class that it is time to stop tolerating graft.
The slew of recent high-profile graft cases in Israel makes it seem that Israeli politicians are more corrupt than others. Part of this can be chalked up to aggressive state prosecutors and an open media. But the problem is not simply one of public perception.
For centuries, all sorts of political movements have claimed the Hebrew Bible as their guide. But as Michael Walzer argues in his new book, the Bible offers no consistent political program. Better to read it, suggests the United Kingdom's chief rabbi, as a text on how to run a society.
Iranian dissidents will tell the United States what they need. But before that happens, Washington must clearly state of its commitment to their cause: regime change.
Pundits predicted that the U.S. Supreme Court's ruling on the Affordable Care Act would make history. In fact, by upholding the individual mandate as a tax, the justices took themselves largely out of the picture, ensuring that the debate over health care will play out in the political sphere, where it belongs.
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From logos to complex marketing campaigns, Deocapac Designs is solutions-driven. As an award-winning agency for "Best in Brand" our team of creatives builds branding packages and develops websites that combine with social media strategies and effective copywriting to make a bold mark on your target audience. Deocapac Designs is the place where really good creative is served.
Visit Deocapac's Portfolio to view our works of art and then check out our Creative Menu to learn more about how we make impressions that last.


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It's time to delve into the Wales history files again. Following a hugely successful first series last autumn, the second series of Hidden Histories, which follows the investigative work of the Aberystwyth-based Royal Commission on the Ancient and Historical Monuments of Wales is narrated by Huw Edwards. Once again, in this series the investigators visit sites across Wales and across time, from Anglesey to Swansea and the Bronze Age to the 1960s.
Lots of information is available about the sites featured in the series, as well as many others, in the Episode Guides, or you can search for more on the online database Coflein.
You can read about the work of the Royal Commission in the Hidden Histories book .
A selection of viewers' comments about the programme are being posted on this site. Please follow this link to Anything to Add?


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Written by PETA
Wherever Sarah Silverman goes, she seems to leave a stream of puzzled people in her wake. Are she and longtime beau, Jimmy Kimmel, on or off today? Is she really getting it on with Matt Damon? Is she Tom Selleck's long-lost sister?
But there is one thing that Sarah makes very clear: She doesn't eat meat. In the November 2009 issue of Marie Claire, the comedian/actor said the following:
"When I was 9 or 10 years old, my dad took me over to a neighboring farm to help get stuff for the meal. The farmer, Vic, told me to look at all the turkeys and pick one out. I saw a cute one with a silly walk and cried, 'Him!' Before my pointing finger had even dropped to my side, Vic had grabbed the turkey by the neck and slit [the animal's] throat. Blood and feathers went flying. I had sentenced that turkey to death! Up until then, I didn't know where meat came from—and I've been a vegetarian ever since."
Consider that the sight of one turkey being killed for Thanksgiving Day dinner years ago was enough to convince Sarah to go vegetarian. Then imagine how you can help lower the body count this Thanksgiving by sharing information about Butterball's cruelty to millions of turkeys with each and every meat-eater you know.
Written by Karin Bennett
If you have a general question for PETA and would like a response, please e-mail firstname.lastname@example.com. If you need to report cruelty to an animal, please click here. If you are reporting an animal in imminent danger and know where to find the animal and if the abuse is taking place right now, please call your local police department. If the police are unresponsive, please call PETA immediately at 757-622-7382 and press 2.
Follow PETA on Twitter!


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"If you make a diamond shape with the thumb and index finger of each hand and go to sleep surrounding your belly button with it, your soul will come out of your body."
In the Ring Novel, Sadako was assaulted and raped by a doctor named Nagao Jotaro. However, he discovered her darkest secret, finding she is a hermaphrodite, and possesses a man's privates. This was not mentioned in the fims and presumably, she is fully female. Sadako attacked Nagao with her powers, forcing him to toss her down a nearby well and he sealed her within. Foreseeing herself being reborn years later, Sadako vowed revenge on the world and died.
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You'd think only the French could pull off a civilized 1,000-person picnic … outdoors … with everyone clad in white … and leave no trace behind.
Turns out our fair city is getting its chance to bat with le big guns: Diner en Blanc is coming (well, the American version at least).
On August 27, at 7 p.m., rain or shine, 1,000 people will show up at a location disclosed a mere hour before. They will wear white from head to toe and carry tables for two, white tablecloths, white plastic trash bags, and food. Some might take flowers; others, candles. One of those people could be you.
Starting Monday at noon, you can register for your spot on the event's website. Invitations (each includes a plus-one) arrive via email, along with a code of conduct for the evening. If you don't get one, you'll be added to the wait-list.
After table setup and napkin twirling (signaling the start of the meal), there's dinner and dancing to be had. By 10:30 p.m., no evidence of Diner en Blanc will exist.
Except, of course, in your memories.
Register online at dinerenblancchicago.com.
Photo: Artie* / Flickr


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Thanks My Milwaukee Mommy!


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Boof Mongolian Adventures is a family owned and operated company that focuses on Tourism in Mongolia. The company was founded as Boof Mongolian Adventures by Ms ARIUNAA Ser-Od, her sisters Toya, Tungaa and friendly French support. We would organize our tours due to make full the satisfaction for our clients and nice inspiration to the partner entrepreneurs.
About our team
Drivers, cooks, guides, assistants - well, all together we make Boof Mongolian Adventures! Boof has over 100 itineraries and carries many of guests to Mongolia each year. Our depth of local knowledge has allowed us to select the services of only the most professional and reputable suppliers. As specialists, we are always able to make the travel arrangements that best suit your needs.
Violaine COURBON
Our heartfelt thanks to Violaine for her precious time on texts into French.


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2Ch 7:1 | Now when Solomon had finished praying, fire came down from heaven and consumed the burnt offering and the sacrifices, and the glory of the LORD filled the house. | |
2Ch 7:2 | The priests could not enter into the house of the LORD because the glory of the LORD filled the LORD'S house. | |
2Ch 7:3 | All the sons of Israel, seeing the fire come down and the glory of the LORD upon the house, bowed down on the pavement with their faces to the ground, and they worshiped and gave praise to the LORD, saying, "Truly He is good, truly His lovingkindness is everlasting." | |
2Ch 7:4 | Then the king and all the people offered sacrifice before the LORD. | |
2Ch 7:5 | King Solomon offered a sacrifice of 22,000 oxen and 120,000 sheep. Thus the king and all the people dedicated the house of God. | |
2Ch 7:6 | The priests stood at their posts, and the Levites also, with the instruments of music to the LORD, which King David had made for giving praise to the LORD—"for His lovingkindness is everlasting"—whenever [fn]he gave praise by their [fn]means, while the priests on the other side blew trumpets; and all Israel was standing. | |
2Ch 7:7 | Then Solomon consecrated the middle of the court that was before the house of the LORD, for there he offered the burnt offerings and the fat of the peace offerings because the bronze altar which Solomon had made was not able to contain the burnt offering, the grain offering and the fat. | |
2Ch 7:8 | So Solomon observed the feast at that time for seven days, and all Israel with him, a very great assembly who came from the entrance of Hamath to the brook of Egypt. | |
2Ch 7:9 | On the eighth day they held a solemn assembly, for the dedication of the altar they observed seven days and the feast seven days. | |
2Ch 7:10 | Then on the twenty-third day of the seventh month he sent the people to their tents, rejoicing and happy of heart because of the goodness that the LORD had shown to David and to Solomon and to His people Israel. | |
2Ch 7:11 | Thus Solomon finished the house of the LORD and the king's palace, and successfully completed all that [fn]he had planned on doing in the house of the LORD and in his palace. | |
2Ch 7:12 | Then the LORD appeared to Solomon at night and said to him, "I have heard your prayer and have chosen this place for Myself as a house of sacrifice. | |
2Ch 7:13 | "If I shut up the heavens so that there is no rain, or if I command the locust to devour the land, or if I send pestilence among My people, | |
2Ch 7:14 | and My people [fn]who are called by My name humble themselves and pray and seek My face and turn from their wicked ways, then I will hear from heaven, will forgive their sin and will heal their land. | |
2Ch 7:15 | "Now My eyes will be open and My ears attentive to the [fn]prayer offered in this place. | |
2Ch 7:16 | "For now I have chosen and consecrated this house that My name may be there forever, and My eyes and My heart will be there perpetually. | |
2Ch 7:17 | "As for you, if you walk before Me as your father David walked, even to do according to all that I have commanded you, and will keep My statutes and My ordinances, | |
2Ch 7:18 | then I will establish your royal throne as I covenanted with your father David, saying, ' [fn]You shall not lack a man to be ruler in Israel.' | |
2Ch 7:19 | "But if you turn away and forsake My statutes and My commandments which I have set before you, and go and serve other gods and worship them, | |
2Ch 7:20 | then I will uproot you from My land which I have given [fn]you, and this house which I have consecrated for My name I will cast out of My sight and I will make it a proverb and a byword among all peoples. | |
2Ch 7:21 | "As for this house, which was exalted, everyone who passes by it will be astonished and say, 'Why has the LORD done thus to this land and to this house?' | |
2Ch 7:22 | "And they will say, 'Because they forsook the LORD, the God of their fathers who brought them from the land of Egypt, and they adopted other gods and worshiped them and served them; therefore He has brought all this adversity on them.'" |


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Swiftkey Flow beta is now available to everyone! The gesture or Swype-style version of Swiftkey's keyboard, brings a few new tricks to the table that others have yet to fully or even think about implementing. First, it predicts on the fly, so that you can see for yourself what word you are attempting to type. But beyond that, Flow allows you to write out entire sentences without lifting your finger, simply by dropping down to the spacebar in between words. So far, it seems like a fantastic update, once you get used to it.
Download: Swiftkey Flow Beta for Android Phones and Tablets
Swiftkey Introduces Swiftkey Flow, a Gliding and Predicting Typing Experience
Swiftkey, one of the most popular Android keyboards, announced a new keyboard experience today, called Flow. As the name implies, Flow allows you to glide between keys so that you can type words without lifting up a finger. Before you jump in with the "This is like Swype!" comments, I recommend that you watch the video. Swiftkey's version of swiping between keys comes off as being much more predictive than other options. During the video, Flow shows that it can predict words after you have swiped only a couple of letters. According to Swiftkey, it also stays top notch at normal typing for those rapid tappers out there.
There is going to be a beta release of Flow soon, so be sure to stop by Swiftkey's site to sign up.


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Aspire Belle Center Programs
Beginning July 2012, the programs of the Belle Center are being continued and expanded under the Aspire name. Working together, we will grow the unique Belle model of inclusion-based services in Chicago and suburbs.
The Belle Center was founded to promote the rights and expectations of all children to be fully included in the community. They provide a critical bridge between children with disabilities and preschools, elementary schools and other community programs. Through a progressive, inclusive approach, Belle Center-designed programs support children with disabilities and their families.
The collaborative effort between the Belle Center staff and our son's teacher has opened so many doors for him, both educationally and socially.
–Ines Grzeslo, Parent
Aspire continues Belle's unique model through services such as:
- Inclusion Education Initiative gives teachers and community providers the tools and strategies they need to successfully embrace children with disabilities. Our inclusive education support takes place where children participate, such as classrooms, daycare centers and other community settings. We also provide workshops on topics related to kids with disabilities and strategies for inclusion, helping community providers open their doors to all children.
- Therapy and Education Services provide individual education, speech and occupational therapy services to support kids with disabilities at the Belle Center or in their natural environments, such as the family home, school, day camp or other community sites.
- Family Support and Education activities are opportunities for parents and other family members to learn about the negotiating support services through the public school system, navigating the Individual Education Plan process, and accessing resources for recreational and extra-curricular activities.
- Sibling Support provides brothers and sisters of children with disabilities support within a relaxed, non-clinical setting. Through crafts, games, stories and discussion, these workshops focus on peer support and education within a recreational context.
To learn more about Aspire Belle Center Program call 773.878.7868.


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On 24 October 2011 Foam and Delta Lloyd signed a sponsorship contract.
Since 2007 Foam has been one of a number of cultural institutions supported by the BankGiro Loterij. The museum receives a yearly contribution for its collection and for enhancing the participation of its public.
The BankGiro Loterij has a special interest in pioneers within the cultural sector. Preference is given to institutions with an entrepreneurial and innovative vision such as Foam. The structural contribution of BankGiro Loterij makes it possible to work towards the next phase in its history. Foam has an entrepreneurial programme, with particular expertise in bringing together visitors, photographers and sponsors.
De Brauw Blackstone Westbroek is a leading law firm in the Netherlands. Its clients include large international companies and financial institutions. In March 2010 Foam and De Brauw Blackstone Westbroek began a partnership that will continue for at least four years.
De Brauw Blackstone Westbroek N.V. is an international law firm, advising more than 70% of the headquarters of multinationals in the Netherlands. We specialise in providing high-end legal advice in complex transactions and litigation to companies, financial institutions, government and semi-governmental agencies. Over the years, we have built up a wide international network of outstanding independent law firms with which we work in close cooperation. De Brauw employs about 650 professionals in Amsterdam, Brussels, Beijing, London and New York.
De Brauw has mainly two objectives in its cooperation with Foam. Firstly, the development of art and culture - in addition to education and the environment - are a priority in the CSR policy of the office. Secondly, De Brauw has an interest in contributing to the cultural climate of the city. Foam and De Brauw have a similar ambition: to focus on young talent.
Giving people opportunities. That is the mission of the VandenEnde Foundation, the private cultural fund set up by Joop and Janine van den Ende. Since 2001 Foam is one of the cultural institutions that has been supported by the VandenEnde Foundation.
Its main objective is to foster interest in culture and to encourage cultural entrepreneurship. The VandenEnde Foundation therefore gives talented young people an opportunity to grow in their careers by awarding them study and working grants. It was the VandenEnde foundation that also built the DeLaMar Theatre in Amsterdam. The VandenEnde Foundation has a fellowship policy aimed at promoting young talent. So far, around two hundred young talents, ranging from classical musicians to circus performers, enjoy grants from the VandenEnde Foundation to further their development. Some of the great talents that have received grants are the young pianists Arthur and Lucas Jussen, the violinist Simone Lamsma and jazz saxophonist Ben van Gelder. The VandenEnde Foundation has also supported important cultural projects in recent years. A good example is the successful music education programme of the Concertgebouw in Amsterdam. In addition, the VandenEnde Foundation has helped various cultural institutions to strengthen their entrepreneurial focus, such as the Holland Festival and Foam.
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What's going on what are you-
Oh God! What's happened?
And who are you for that matter?
Hello Everyone, welcome to this forum adventure! Yeah I'm not going keep that title it's just the first thing I thought of, oh Nic Cage.
Anyway I've recently become completely smitten by this section of the forum and I wanted to try making one myself. I actually do have a collaborative project in the works but in the meantime I wanted to do something on my own and have it be something a bit more casual. By that I mean that I that I don't have a plot structure in mind, heck I don't even really have much of a plot in mind and that when it comes to artwork I'm going to focus more on getting it done and getting it done quickly instead of getting caught up in trying to make it look finished and professional. I'm also going to be experimenting with the art a lot to try and establish a good process for churning this stuff out so don't be surprised if some of the panels look a bit different than others, though I am going to try and keep the style itself constant.
As for an update schedule, I make no promises other than that I have committed myself to this thing and will try my best to get something up AT LEAST once a week to keep it relatively fresh. However, the amount of free time I have changes every week and I often have a lot on my plate (in fact I should really be working on a paper right now X.x) so please be patient with me. Well I think I've rambled enough so without further ado, SUGGESTIONS PLZ?


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Sail America President Sally Helme recently asked me to reflect on recent trends on both the retail side of the boating market and the broader retail industry, as well as how I think those indications may serve as a bellwether for the sailing industry in the months ahead. So many of the retail business statistics in the sailing industry are mixed in with the general boating numbers, and impacted by retail trends overall, that I felt it was important to reflect on recent trends from both areas.
Retail trends so far in 2010 continue to show mixed results, even within the broader retail industry. Overall, we continue to see a slow, cautiously optimistic recovery, which for most companies is still far short of the pre-October 2008 levels of business.
Very recently, a composite of 30 larger retailers, as reported by Kantar Retail, showed a strong November 2010, with comparable store sales increasing in the +6.0% range. Analysts are quick to caution that much of this could have been driven by "bargain seeking" consumers, taking advantage of significant discounts and especially the recent "Black Friday" weekend.
According to the research firm ShopperTrak, retail spending increased 0.3% on the day after Thanksgiving – "Black Friday" – as compared to last year, and overall store traffic increased 2.2%, for the three-day weekend. "This means the American shopper has adapted to the economic climate over the last couple of years and is possibly spending more wisely as the holiday season begins."
In the marine industry, we continue to see an overall slow recovery, with very mixed results for retailers, e-commerce, and wholesale businesses. The overall trends seem to be in the +1.0 to 2.0% range, with wide variances based on company size and channel. Exact numbers are difficult to quantify as so many of our sailing industry businesses are private, or like in our case at West Marine, trailing public numbers. Recent traffic in boat shows, such as Fort Lauderdale, are "rumored" to be in the 5-6% range, Newport in the +10% range, and Annapolis Sail "up considerably." Show management typically doesn't report exact traffic numbers, with some dealers reporting nice increases from 2009, but most still far short of pre-2008 levels. Caution continues to reign, and many companies are seeing gains that are presently simply filling gaps left by businesses that are out of business, masking continual industry contraction.
At West Marine, we reported that our comparable stores (revenue in stores open at least one year) rose 3.7 percent for our fiscal Q3. "Comparable" or "comp stores," reporting is a typical key retail metric as it excludes revenue from stores that have been newly opened or closed. Our revenue from stores opened during 2009 and the first three quarters of 2010 totaled $9.2 million, but we also closed stores during the same period, reducing revenue by $8.3 million. We are continuing to follow our multi-year "real estate optimization" program with the goal of having fewer, larger stores, which can offer customers much larger assortments of core boating gear and apparel. We continue to see strength in categories of products that focus more on "DIY" and recently, a slow rebound of large ticket items.
In talking to some of the more successful retailers and dealers in the industry, the most common theme of successful companies is continual "Innovation" with how they deliver to their customers, or do a better job offering more of what their customers want. Really creative programs in yacht brokerages focusing on more "concierge" services seem to be yielding results.
As far as the upcoming months, I personally think we will see more of what we have witnessed in 2010 continue into 2011. Recent marginally positive unemployment results in November of 2010 as reported by the NY Times, showed a relatively small, but positive increase in jobs of 39,000. This among global economic concerns, continue the continual stream of both positive and negative mixed news.
From the November 24 Kiplinger forecast: "Look for GDP in 2011 to roughly match this year's expected 2.8% gain. Although much improved over the 2009 decline of -2.6%, that's subpar for a recovery. In fact, the sluggish growth which followed a rousing 2009 fourth quarter (5% annualized growth) and first quarter of this year (3.7% annualized growth) is raising fears that the economy may tumble into recession again. We think there's enough momentum to avoid a near-term decline."
"The economy is actually a bit stronger than first thought. GDP increased at a 2.5% pace in the third quarter, rather than 2% as initially estimated. Growth is holding steady so far in the current quarter, and 2011 should bring more of the same moderate gains."
In closing, now more than ever, we all have an opportunity to continue to grow our businesses and our industry, by listening carefully to what our customers are asking for and delivering it to them. The lifelong passionate sailing customers, and people wanting to get on the water, are still there for us to serve, but we have to be very creative to entice them to continue to choose to spend their dollars with us, by offering products and services that make it obvious to them that it's a worthwhile endeavor to pursue.


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Our crowd-pleasing tailgate desserts can be made ahead, are easy to transport, and don't require forks or refrigeration.
Ultimate football rivalries deserve ultimate cookies–so plan to take these along for your next tailgating extravaganza. They are everything chocolate chip cookies should be.
Recipe: Ultimate Chocolate Chip Cookies
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text: Government: Parliamentary Democracy Population: 82,500,000 Major Religion: Roman Catholicism Monetary Unit: Euro (EUR - EU's single currency) Annual Growth: 0.15% Health & Welfare: Germany has one of the most comprehensive and generous systems in the world. It includes health, old age, disability, unemployment insurance, child support, public housing and veterans aid. Economy & Jobs: Manufacturing, industry, mining, farming, forestry, fishing, energy, banking, and tourism. Main Attractions: Berlin, Frankfurt city, L�beck medieval town, Munich city, Rhine Valley, and Weimar pilgrimage site. Immigration: German citizenship can be acquired in a number of ways. The most common are by descent, birth, marriage, extension of award, and business. Tourist, student, and work visas are also available. Select the option that best suits your needs and start the application process immediately.


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OverviewAerodactyl is the definition of fast, outpaced only by Accelgor in RU. It can take advantage of this by simply equipping itself with a Choice Band and hitting stuff hard or supporting the team with a fast Stealth Rock and Taunt. It's not all good news for Aerodactyl though, as its subpar defenses don't let it take advantage of its great typing and leave it very vulnerable to priority and Choice Scarf users. Additionally, it has a weakness to Stealth Rock, further shortening its lifespan. Don't be fooled, however; this prehistoric beast is still one of the most deadly offensive Pokemon in the tier, and underestimating it can very well cost you a few games.
Aerodactyl's incredible Speed, good Attack stat, and great coverage make it an excellent Choice Band user. Like other Choice item Pokemon, this set requires a bit of prediction to work properly, although the fact that all of its moves have a wide range of neutral coverage eases this a little. Stone Edge, as unreliable as it is, is Aerodactyl's STAB move, hitting everything that doesn't resist it for a good chunk of damage. Earthquake maims Steel-types such as Aggron that try to switch into predicted Stone Edges. Aqua Tail hits Rhydon harder than anything else on this set, securing a 2HKO. Double-Edge rounds out the set by providing Aerodactyl with a strong neutral coverage move that takes full advantage of Rock Head. Team Options & Additional Comments >>>
This set is an excellent addition to most offensive teams in need of a good way to shut down teams that rely on setup moves a lot, such as stall and Spikes-based offense. It also acts as an excellent check to Fire-types such as Moltres and Entei when pitted against more offensive teams. Stealth Rock is the main option in the first slot because Aerodactyl is one of the fastest and most reliable users. Roost can be used in its place if you already have Stealth Rock elsewhere on your team, and also gives Aerodactyl some longevity by healing off Life Orb and Stealth Rock damage, as well as weaker attacks. Taunt can mess up Pokemon looking to set up on Aerodactyl, such as dual screens Uxie, lead Smeargle, and Quiver Dance Lilligant. Stone Edge provides Aerodactyl with a strong STAB move to tear holes into opposing teams with. Earthquake gives it a means of damaging the various Rock- and Steel-types that resist Stone Edge, such as Aggron, Rhydon, and Steelix. Team Options & Additional Comments >>>Other OptionsAerodactyl's average movepool means that most of what it can do well has already been covered in the above set descriptions. The only set not really covered is a Life Orb + Hone Claws set. However, Aerodactyl is usually better off just blasting stuff away with a Choice Band than wasting time to set up Hone Claws. There are a few gimmicks that you might want to try as well. After all, who knows? Maybe you'll be pleasantly surprised by the results. A Power Herb + Sky Attack set stands out among the more viable of these gimmicks, as the combination has lots of surprise value and gives Aerodactyl a one-time 140 Base Power STAB move to use on a wall such as Tangrowth for a potential free KO. Other moves such as Thunder Fang, Ice Fang, Tailwind, and Whirlwind can seem tempting, but they are generally inferior to the moves listed above. With access to both Sunny Day and Rain Dance and base 130 Speed, Aerodactyl can make for a very effective early-game weather setter when equipped with the appropriate weather-extension rock. Checks and CountersCountering Aerodactyl is all about having the sheer bulk to tank multiple hits from it. For this reason, Pokemon such as Torterra and physically defensive Slowking, which fear nothing that Aerodactyl commonly carries, make for the safest counters. Tangrowth and Ferroseed are a very close second to the aforementioned two, except they are very vulnerable to surprise Fire Blasts and Fire Fangs. Steelix and Escavalier can easily tank just about anything Aerodactyl can throw at it, but an Earthquake or Aqua Tail from the Choice Band set will put Steelix in 2HKO range of that same attack later. Ground-types, such as Rhydon, Golurk, and Sandslash, are very effective checks against versions lacking Aqua Tail. Qwilfish is as well despite the Earthquake weakness, because it can easily threaten Aerodactyl in return with Waterfall. Aggron can play mindgames with Choice Band Aerodactyl, forcing it to predict correctly, lest it be the next target of its mighty Head Smash. Another way of ensuring Aerodactyl won't do too much damage is by packing strong priority attacks such as Feraligatr's Aqua Jet and Spiritomb's Sucker Punch. Finally, common fast Choice Scarf users such as Manectric also make for effective checks. |


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Meditation In Motion
A Labyrinth is simply a spiraling pathway. It has been around for about 4000 years and has been found in many religious traditions and in various forms around the world. It is a symbol of wholeness and healing. People walk the labyrinth to:
- Ponder New Challanges
- Discern Direction
- Release Tension/Grief/Anger
- Gain Insight
- Recover Calm and Peace
- Restore Focus
- Discover New Perspectives
- Perceive Resolution
- Recognize Abilities
- Seek the Divine/Holy
- … to Simply "Be"


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Miami Hurricanes
- Year: Sophomore
As a Recruit: Howard was recruited from Miramar (Hollywood, FL) class of 2012. He committed to Miami on 2/1/2012.
May 16
Feb 1
Feb 1
Jan 27
Jan 20
Jan 15
Jan 13
Jan 9
Jan 7
Dec 14
Dec 12
- sfecoach Brett Goetz
RT @jcshurburtt: My man @GerryHam247 thinks 2015 CB Tyrek Cole is the next Tracy Howard and could be better. Both from @MiramarSports
- jcshurburtt JC Shurburtt
My man @GerryHam247 thinks 2015 CB Tyrek Cole is the next Tracy Howard and could be better. Both from @MiramarSports
- SBNRecruiting SB Nation Recruiting
RT @sfecoach: Stedman Bailey, Geno Smith, Brandon McGee, Rodney Smith, Conner Vernon, Duke Johnson, Deon Bush, Tracy Howard, all SFE th ...
- sfecoach Brett Goetz
Stedman Bailey, Geno Smith, Brandon McGee, Rodney Smith, Conner Vernon, Duke Johnson, Deon Bush, Tracy Howard, all SFE this weekend!
- CoreyLong Corey Long
@VBCaneFan @Jon_Bastian Baloney, you obviously never read anything I said about Tracy Howard, Malcolm Lewis or the Autobot. Or Jamal Carter
- MsAmyCampbell Amy Campbell
LB Jermaine Grace says #Canes recruiting the hardest & it's Tracy Howard & Malcolm Lewis giving him the biggest earful: http://t.co/uwvu18LH
- CNee247 Chris Nee
RT @COACH_T_Y Real Deal next Tracy Howard RT @CNee247: Miramar 2015 CB Tyrek Cole Claims #Miami Offer http://t.co/YhMojd1u via @InsideTheU
- InsideTheU InsideTheU.com
RT @SandySjamison: @InsideTheU Goodmorning to you hurricane nation. I hope Eddie Johnson and Tracy Howard have a big game against GT.
- InsideTheU InsideTheU.com
DB Artie Burns Watching Deon Bush and Tracy Howard http://t.co/EUHrzyuK via @247Sports
- CNee247 Chris Nee
DB Artie Burns Watching Deon Bush and Tracy Howard http://t.co/X5tRrQL1 via @InsideTheU #Canes
- Edit
What Could Have Been: Defense
7 days agoToday, we cover the defense when wondering which former recruits could have helped West Virginia most this fall. More
- Edit
2015 CB Cole Discusses The Spring
13 days agoMany coaches from the top schools from around the country have visited 2015 cornerback Tyrek Cole this spring. Read here for the latest. More
- Edit
Decision Coming Soon for CB Patten
17 days agoBooker T. Washington cornerback Nigel Patten has received a number of offers and a decision is likely coming soon.
More - Edit
Spring Review: Defensive Backs
30 days agoWe conclude our spring review series today by taking a look at the defensive backs and their progress. More
- Edit
Post-Spring Depth Chart
39 days agoHere is a look at the depth chart for the Miami Hurricane at the conclusion of spring practices. More
2012 U.S. Army All-American Bowl selection. ...Named to the Super Southeast 120 by the Mobile (Ala.) Press-Register. ...One of the Top 25 senior players in Broward County, Fla., according to the Miami Herald...Top player in Broward County according to the South Florida Sun-Sentinel. ...Named one of the 50 best prospects in the state of Florida by the Gainesville (Fla.) Sun. ...Team won Class 6A championship his sophomore season.
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PRIVATE MEMBER'S MOTION: ANGLICAN CHURCH IN NORTH AMERICA ( GS 1764A and GS 1764B)
Mrs Lorna Ashworth moved a motion, and following debate the motion was amended; and was carried by the Synod in the following amended form:
'That this Synod
(a) aware of the distress caused by recent divisions within the Anglican churches of the United States of America and Canada;
(b) recognise and affirm the desire of those who have formed the Anglican Church in North America to remain within the Anglican family;
(c) acknowledge that this aspiration, in respect both of relations with the Church of England and membership of the Anglican Communion, raises issues which the relevant authorities of each need to explore further; and
(d) invite the Archbishops to report further to the Synod in 2011.'
Audio of session
The Chaplain General for HM Land Forces and Archdeacon for the Army, the Chaplain-in-Chief and Archdeacon for the Royal Air Force and the Chaplain of the Fleet and Archdeacon for the Royal Navy gave a joint presentation on the work of the Forces chaplaincies.
Following debate, the Synod voted to take note of the report; one aspect was recommitted to the Revision Committee for further revision.
Audio of session - part one
Audio of session - part two
Your Church Wedding Whether you're just dreaming of a church wedding, or well into the planning already, your church wants to help and support you.
Shrinking the footprint The Church of England's environmental campaign aimed at resourcing the reduction of the church's carbon footprint.
Churchcare A comprehensive resource for anyone involved in the running of a church, with a wide range of practical advice and tips.
Call Waiting The Church of England wants to encourage gifted and committed young men and women, from all backgrounds, to consider whether God is calling them into ordained ministry as priests.
The Church and Community Fund The CCF encourages the church to engage with their local communities by funding effective and innovative community outreach projects.
Going for Growth Going for Growth challenges the Church of England to work towards every child and young person having a life-enhancing encounter with the Christian faith.
Church Legacy Find out why and how to make a Will, and see how gifts in Wills make dreams come true!
Worship Workshop WorshipWorkshop offers Church schools a way of creating engaging collective worship.
Church House Publishing The Archbishops' Council publishes a range of liturgy, reference and other resources under the CHP imprint.
Parish Resources All things stewardship: resources and guidance on preaching, giving and fundraising with helpful online guides.
Diocesan websites The Church of England comprises two Provinces, Canterbury and York. Each province is broken down into dioceses. There are 43 in England (44 including the Diocese in Europe).
Communications Training High quality media, presentation and new media training for the Church of England and related charities. Find out more about our current courses.
Lambeth Palace Library The historic library of the Archbishops of Canterbury. Its collections and those of its sister body the Church of England Record Centre (CERC) are freely available for research.
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Celebrate 200 years of Church Schools The National Society celebrates 200 years of Church schools in England and Wales. Find out more about the anniversary and the work of the National Society.


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Red, That system can probably scrape by with a couple of minor changes (I assume you mean you have a Radeon 6850). 1) Much more RAM. As much as your motherboard can manage. 2) 64-bit Windows. There are already rumblings about upcoming games requiring 64-bit. My own HTPC has a Phenom II X2 550, which seems to benchmark around the Q6600, Radeon 6850, and 12 GB RAM, and I have no problems with anything I've thrown at it.
That said, Q6600 is at the very tail end of its usefulness, and it's unlikely that your motherboard supports a significant upgrade over it. You'll be able to get by for now, but budget for a new mobo, processor, and RAM (i.e. faster, since your current mobo likely doesn't support anything close to the latest-and-greatest) in the near term.
Can't recommend a good wireless mouse and keyboard, but if you don't already have one, definitely get a wireless 360 controller for PC. I think you can get a dodgy third-party receiver that will work with your existing 360 controllers for cheap, but I'd recommend ponying up the $50 for an official MS one (which comes with a controller, and it's always nice to have extras).


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Dear Dr. Date,
My girlfriend found out I lied about my parents dying, and I'm really an undercover FBI agent trying to infiltrate a surfing group. Now, my best friend has kidnapped her and is demanding I skydive with him and his surfing buddies! How can I patch things up with the lady?
Dear Special Agent,
I've seen your type walk into my office before — you're so disgustingly healthy you probably take the skin off chicken. You might be a celebrated college quarterback, but you don't have many field hours, and worse than that, you're young, dumb and full of cum.
And lying about your parents being dead? Rookie mistake — you put a knife in this surfer chick's heart, bro. Winning her back is going to be a big job, and you can't go it alone. My advice? This is a two-man job: get a partner.
It can't be just anyone though. This is a task for the startlingly insane: You're going to need somebody so obviously unhinged that he wouldn't hesitate to pull your skydiving friend's endocrine system out of his body.
And to be sure he's not going to upstage you in front of your girl, choose a partner who's a little past his prime, you know, a guy who can barely run and loves meatball sandwiches but who isn't afraid to jump up on a desk and hang 10, if you know what I mean. He also shouldn't be much of a looker: A straw-haired, buck-toothed, maniac with a crooked maw should fit the bill.
Once you get to this point, break out of your shell and come clean with your girlfriend: No more masks, no more lies. You can't run around like Richard Nixon and expect to get off scot-free with this girl. If you take care of her, time and the ocean will take care of your kidnapping friends.
Also, don't forget to check your chute.
—Dr. Date
Dear Dr. Date,
I've been stood up by more guys than I can count. And the frequency is on the rise. So my question is, is it me? Or is there something else going on that is causing me to end up dateless night after night?
—Date Night, Dateless Night
Dear Dateless,
I hope this is just hyperbole, or proof that you're not a math major: There can't be that many guys who've stood you up! But without having any more information to go off, I've got to say you're either incredibly unlucky, or perhaps there is something about you, a bad aftertaste that causes guys to lose their lust.
You can't let what guys have done to you in the past affect the way you approach them in the future. Don't dwell on what happened to make those guys fall out of love, instead, think about what you can do to make the next guy fall to begin with.
—Dr. Date
Dear Dr. Date,
Even if sex life is already rich, imagine you have little more energy, if erection stay harder or you go just little longer. Or maybe you worry when you climb under covers that start something you can't finish.
Is easier than ever to promote strong libido, firm, natural erection and enhanced desire. Truly!
Now thanks to exciting natural breakthrough, you get erection "on demand" and when you do, sustain long enough — and keep firm enough — to fully satisfy wife in bed. Even if you're in your 50s, 60s, 70s, 80s or older!
As doctor, I learn over years what may surprise you — age has very little to do with sex. There are men out there have best sex of their lives well into their 80th year and beyond.
And those men have three key things in common sex-starved friends don't:
Hard, recurring erections, heightened desire and stamina, and reproductive system at top of its game. Lucky, no?
But you too give your body nutrients it needs to support entire sexual health. Other treatment option for impotence include vacuum device and surgical implant.
—Borscht In Bed?
Dear Russian Supplement Manufacturer,
You had me on edge, waiting to hear the magical penis pill pitch in this whole rambling mess, but, alas, you disappoint. However, I'm sure my readers will be comforted to hear a fellow medical practitioner say they can look forward to another 60-plus years of good sex.
—Dr. Date
UMN students have traveled to Florida colleges to collaborate with students on various projects.
When UMN students plan for a vacation, having trip cancellation travel insurance is a worthwhile commodity to check out.
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A week ago I was standing in line for The Hunger Games. After three years of waiting, it was exhilarating to finally watch the characters and places I had formed in my imagination take shape and flesh and color on screen. I left the cinema that night with the intention to watch the film again – this time with my fiance who has not read the book – compare notes, and write a review dialoguing the two perspectives.
And then a monster virus struck. Not a computer virus – the old-fashioned kind that strikes your immune system. Talk about annoying. I am the kind of person who is too busy to get sick. I don't allow colds or flu-like symptoms to interfere with my work or writing or projects, damnit. So imagine my shock when this wretched virus knocked me out flat. For four days. My brain and muscles are equally exhausted. I feel completely out of the social media loop. And I'm sure hundreds of Hunger Games reviews have been written and posted by now, such as this one by my good friend Nicole M. Miller.
Today is the first day that my brain has been able to grasp a coherent, fully formed thought. The rest has been a haze of fitful sleep, NyQuil, fabulously bad '80′s television (Remington Steele) and Torchwood marathons. (More on the latter two in a future post.)
Three Hunger Games items have punctured through the drug-head fog this past week. First, box office numbers. The Hunger Games made $155 million during its opening weekend, making it the third-best opening weekend ever. Thar's right – it surpassed all Twilight movies and all Harry Potter installments save the final one (Deathly Hallows Part 2). Pretty impressive for the little studio Lionsgate.
Writers such as Melissa Silverstein and Thelma Adams have pointed out that HG's success is all the more significant due to its central female protagonist. This isn't a blockbuster about Spiderman or Batman. Katniss is a sixteen-year old girl, and this powerful character is providing a strong role model for young girls across the country.
Second item: Astonishingly, despite the popularity of Katniss, some have criticized Jennifer Lawrence's body in the film, claiming she doesn't look "hungry enough" or that she is "too big" to play Katniss. One critic (Todd McCarthy) actually calls attention to Lawrence's "lingering baby fat." Such comments are repulsive. Are you frickin' serious?
I found Lawrence utterly refreshing to watch onscreen. She is healthy, normal, and, um, beautiful. There are too many ultra-skinny women in film, television and media. How sad is it that underweight, dieted bodies are the "norm" for Hollywood – so much so that critics cannot recognize a normal, fit, and healthy body on screen? Thankfully people have been speaking out against this appalling bodysnarking, and the reviewers ought to feel ashamed of themselves.
Third item: the Jezebel article. You know what I'm talking about if you've read it. For those that haven't, here's a brief summary: Several Hunger Games fans expressed racist comments on Twitter and Tumblr after watching the film last weekend. Apparently, even though Suzanne Collins described Rue and Thresh as having "dark brown skin" in the novel, these viewers were shocked and angry that their "favorite characters" were black in the film. One particularly loathsome tweet said that the casting "ruined" the movie, and another confessed that Rue's death was not as sad because she was black. WTF?
I don't know what's worse: that this kind of racism is still present – and so highly vocalized! – in 2012, or that the hateful tweets were predominantly posted by teenagers. In what kind of culture is this behavior deemed okay to our youth? I am outraged that this kind of prejudice is still so clearly and unapologetically demonstrated in this country. It's the kind of prejudice that leads to vigilante citizens shooting an unarmed black teenager wearing a hoodie.
A review on the actual film will be posted in the coming days. For now I thought it important to recognize that The Hunger Games is highlighting issues that extend far beyond war and youth and hunger. This movie is (unintentionally, I'm sure) provoking dialogue on the current state of gender, body image, and race in this country. That's pretty powerful.
What conversations have you seen or been a part of relating to The Hunger Games?


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Pantomime stars switch on lights – oh yes they do
8:08am Saturday 17th November 2012 in News
STU FRANCIS and the cast from the Albert Halls panto Snow White and the Seven Dwarfs will be switching on the Middlebrook Christmas lights this year.
The event is taking place at 4pm on Thursday, November 22, outside Vue Cinema.
Churches Together will start the celebrations with some festive carols followed by a short sketch by the panto cast and a song from Kristina Castellina, who plays Snow White.
Pupils from schools around Bolton, Bury, Chorley and Wigan who work with the Volunteer Reading Help charity will also be invited to join the stars. The youngsters have taken part in a design a Christmas postcard competition and the winner will be invited on stage for the lights countdown and to flick the switch at 4.45pm.
Father Christmas will then arrive at the celebrations to welcome the children to his grotto for Christmas gifts.
Heather Crank-Ingham, from the Middlebrook retail park, said: "We are looking forward to marking the beginning of Christmas and welcoming Stu Francis and the cast of Snow White to Middlebrook to switch on our Christmas lights along with the local schools associated with the Volunteer Reading Help."
11:49am Sat 17 Nov 12
I, Ludicrous
5:02pm Sun 18 Nov 12
10:32pm Sun 18 Nov 12
I, Ludicrous wrote:your comments seem a little mis-jointed! The article clearly stated Middle brook, no mention of the town centre. Maybe these lights will be turned on by some nobody. At lest Stu has been around for quite some time, and why shouldn't he promote his panto, after all, a lot of the cast are performing the switch on. Seems you have something against him?
The Middlebrook Christmas lights? Not the town centre Christmas lights then? Are the Albert Halls in Horwich now? Hey, nobody told me. There's me lamenting the demise of Bolton town centre when all along it's simply moved. By the way, how come Stu Francis gets to publicise his extremely lucrative annual venture on the back of it all, once again?
2:38am Mon 19 Nov 12
2:38am Mon 19 Nov 12


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If you had a dollar for every time you've been told that asking for money in lieu of wedding gifts is a faux pas, the point would be null.
Let logic trump tradition with a registry from Hatch My House, a long-overdue site that lets guests chip in on the down payment for something really useful: a house.
After signing up, enter information about your plans and design a virtual dwelling. A variety of watercolor drawings let you dictate setting (suburbs, beach, city), style (brownstone, colonial), and color. Then connect the registry to your bank account via PayPal. Finally, pay a one-time $25 fee and your page goes live.
The finished product looks like a virtual dollhouse, and gifters can click on specific parts — both exterior ($75 for a window) and interior ($200 for an armoire). Plus, transaction fees never top 3 percent. A small price to pay to avoid yet another glass pitcher.
Available online at hatchmyhouse.com.
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By: Alicia Pennisi
ENDWELL, N.Y. - If winning 3-straight state championships wasn't enough, the Maine-Endwell football team may soon have another reason to celebrate. Voted by fans, the Spartans made it all the way to the final four of the USA Today people's champion contest, vying for the title of america's favorite high school football team.


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T.I. is in full grind mode as he gets ready for the 2012 release of his eighth studio album Trouble Man.
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Livin' Large Larry's Son Driving a Stolen Vehicle [AUDIO]
I for one respect the Billings Police Department. I have personal friends with-in the department. I teach my two teenage boys to respect the law. But for the 2nd time in the last 4 months my youngest son, Devin was pulled over for really nothing. Yes he drives an old "beat up" car with a mis-matched bumper. Yes he has "skateboarder" hair. Yes he is only 15.


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Roasted Red Onion, Rocket and Parmesan Salad
This salad is made with slightly charred oven-roasted red onions, which are then marinated in olive oil and lime juice and layered with rocket leaves and flakes of parmesan. A truly wonderful combination.
Vegetarians might like to know that a vegetarian parmesan-style cheese is available from www.bookhamcheese.co.uk
Serves 4
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You will also need a good solid baking sheet 15 x 11 inches (37.5 x 28 cm). |
This recipe first appeared in Sainsbury's Magazine (May 1993).
First of all, peel and cut each onion in half then into approximately ¾ inch (2 cm) sections, and arrange these in a single layer on a lightly oiled baking sheet. Use 2 tablespoons of the olive oil to brush the surface of the slices, then season them with salt and pepper and place on a high shelf in the oven for 25-30 minutes, until they are beginning to look toasted at the edges and feel tender when pierced with a skewer.
Meanwhile make the dressing: using a pestle and mortar crush the garlic with 1 teaspoon of salt until you have a smooth creamy paste. Whisk in the lime juice, 2 tablespoons of oil and a good grinding of black pepper. As soon as the onions are ready, remove them from the oven and, using a palette knife, transfer them to a bowl.
Pour the dressing over while they are still warm, tossing them around to coat well with dressing. Leave them on one side until they're quite cool.
To assemble the salad, arrange the ingredients in layers, first a layer of rocket leaves, then onions and then flakes of Parmesan, sprinkling with dressing as you go.
Continue like this, finishing off with a layer of Parmesan, and serve with ciabatta warm from the oven.
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Location: Genomics and Gene Discovery
Technical Abstract: Brachypodium distachyon is a promising model for studying temperate grasses, most importantly wheat. Small RNA (smRNAs), especially 21 nt and 24 nt smRNAs, play essential roles in plant development and physiology. We performed seep sequencing of smRNA repertoires in Brachypodium and wheat and found that these two species shared only ~3% of their smRNAs. Twenty-four nucleotide (nt) smRNAs were the most dominant, but the least redundant for both Brachypodium and wheat. In addition to numerous conserved microRNA (miRNAs), 13 and 39 novel miRNAs were predicted in Brachypodium and wheat respectively and a subset of miRNAs were experimentally confirmed. Unexpectedly, only ~9% of smRNAs were shared by Brachypodium smRNA derived from reproductive and vegetative tissues and significant differential expression of smRNAs were observed. Wheat smRNAs were found to have perfect match to more than 13% OF estS INVESTIGATED. Many of these ESTs represented genes involved in endogenous and exogenous stresses and stimuli as indicated by Gene Ontology analysis, indicating that the regulation of stress responsive genes may heavily involve smRNAs. smRNAs of 21 nt were the most abundant among smRNAs matching wheat ESTs, whereas 23 nt dominated the smRNA mapped to their own genomic sequences. When Brachypodium and wheat smRNAs were mapped to rice chromosomes similar distribution pattern were found. There conserved smRNAs were located at both genic and intergenic regions with more 21 nt smRNA than 24 nt ones, indicating 21 nt smRNAs were evolutionarily more conserved. The conservation and divergence of smRNA repertoires in grass species were discussed.


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Governor Kasich Signs Ban on Certain Abortion Coverage
Governor Kasich has signed into law a bill to prohibit abortion coverage by health plans operating in the new insurance exchanges that were laid out in the federal health care overhaul.
The American Civil Liberties Union of Ohio has claimed the measure is unconstitutional and has said it would fight it in court.
The ACLU of Ohio says the ban on abortion coverage violates a voter-backed state constitutional amendment that says no law or rule should prohibit the purchase or sale of health care or insurance.
The constitutional amendment was approved by voters during the last month's election.
The abortion bill was among 13 measures that Governor Kasich signed into law on Wednesday.


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I Sell the Dead
19th century justice has finally caught up to grave robbers Arthur Blake and Willie Grimes. With the specter of the guillotine looming over him, young Blake confides in visiting clergyman Father Duffy, recounting fifteen years of adventure in the resurrection trade. His tale leads from humble beginnings as a young boy stealing trinkets from corpses, to a partnership with seasoned ghoul Willie Grimes as they hunt creatures unwilling to accept their place in the ground. The colorful and peculiar history of Grimes and Blake is one filled with adventure, horror, and vicious rivalries that threaten to put all involved in the very graves they're trying to pilfer. Also a Major Motion Picture.
I Sell the Dead (One-Shot)
By: Glenn McQuaid, Brahm Revel
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- October 07, 2009
- Genres:
- Horror, Movies & TV
- Series:
- I Sell the Dead
When 19th Century justice catches up with the infamous grave robbers Grimes and Blake, the condemned Blake reveals to the peculiar clergyman, Father Duffy, who you can never... ever... trust a corpse. From GLENN McQUAID's award winning motion picture starring DOMINIC MONAGHAN, LARRY FASSENDEN and RON PERLMAN.


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Last week eight hotel executives, a marketing executive, and a Nevada state assemblywoman did something that Bill Fortier, senior vice president-development, the Americas at Hilton Worldwide and chairman of the Latino Hotel Association described to those in attendance as "fun, and a bit shocking." In the Pavilion at Tropicana in Las Vegas, the executives ditched their business suits and donned headgear and boxing gloves and promptly began pummeling each other.
I was lucky enough to be ringside to witness the association's new signature fundraising event, Battle of the Brands (full disclosure: I served as a judge) and let me tell you, it was quite a scene. After months of buildup, the five bouts where nothing short of entertaining for the gathered crowd, and five winners got to take home belts as prizes. But the real winners of the event were future hoteliers—particularly those of Latin American descent.
Proceeds from the fundraiser went to endowments for Latino hospitality students at the University of Nevada, Las Vegas, the University of Houston, and Temple University. And, deans from all three schools were on hand for the event, which Angela Gonzalez-Rowe, president of the association says is to become the association's signature fundraiser and attraction at future conferences.
But boxing aside, the inaugural LHA conference centered its two days around the idea of education and building minority ownership of hotels.
That idea was the basis of the "View From The Top" panel discussion, of which I had the pleasure of moderating. Fortier; Rajiv Trivedi, executive vice president of franchise development at La Quinta Inns & Suites; Tye Turman, senior vice president of North America select service development at Marriott International; and Michel Montant, corporate director of development for Grupo Posadas; not only discussed the state of the industry and development opportunities, but also the need to recruit and educate potential Latino hotel owners into the industry.
As Gonzalez-Rowe also pointed out, "We need to educate on things such as asset management and lending procedures for Latinos interested in the industry."
Many of the sessions at the conference hammered that point home concentrating on various aspects of entering the lodging business, including how to negotiate a franchise or management agreement; learning operations, and strategic operations in high-threat areas.
Another highlight of the conference was a discussion led to Simon T. Bailey of the Brilliance Institute, who inspired the audience to think differently about branding and to use an emotional branding approach to marketing hotels.
For those that attended the inaugural conference, it was an excellent opportunity to learn how to help build the future of the industry through minority ownership; something the panelists on the View From The Top panel all said was vital to the long-range success of the industry. And afterward, they all got to see their fellow colleagues step into the ring and fight for the education of future hoteliers.


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Great for all musical needs. I really enjoy going to barker's music. They are super helpful and friendly and the prices are reasonable. They have a great selection of quality items too!
Not helpful. This music store is not very helpful to many musicians. I have been here many times and it always seems like they keep the same stuff on the shelfs. I would not be surprised if they have stuff on their shelfs from the 80's, that is how…
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text: The Show Catwalk Fashion Shows Spring/Summer 2007 Ready-To-Wear Zandra Rhodes 20 September 2006 PERHAPS it's because she's a seasoned fashion figure that Zandra Rhodes felt justified in putting on one of the week's longest shows – and she managed to keep us all interested until the end. Well, bar a few catcalls from photographers desperate to get on and bags a place at Giles. Beginning with the paparazzi not knowing quite where to look as a pink babydoll-clad glittering Kimberley Stewart struck an accommodating pose on one side of the catwalk while Minnie Driver (in a scull-printed head scarf), sat demurely on the other, the show opened with Erin in a brightly printed crinkle-cut, oriental cloak and clingy tube skirt. With huge Perspex platforms, gravity-defying beehives and swathes of coloured eye make-up - as Zandra herself is famous for wearing – as a backdrop, she put on a show of prints – black, white and red, turquoise, yellow, pink, coral – were they deep sea coral reefs or tropical garden blooms? It wasn't clear, but what was is that Zandra's place on the catwalk is as solid now as it was 20 years ago when she last took to the runway. There were romantic ruffle dresses, some of which were caught up at intervals into an elaborate French blind around the legs, stunning black evening gowns beaded with silver that are bound to walk Rhodes straight onto the red carpet again, childish babydolls in strawberry shortcake pink and the best kaftans in the business – her signature pieces – beaded with tiny pearls and sent onto the runway with the sexiest, most colourful swimwear we've seen this week. Huge beaded jewellery – like colourful Tiffany lamps, made for an enormous dragonfly at the throat or huge square mirrored bangles that place Rhodes' qualifications and imagination far beyond colourful chiffon. Erin, with a crown of pheasant tail feathers and glass lilies, also closed the show – eccentricity as only the Brits can do. (September 20 2006, PM)Dolly Jones


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Berlin hotel reviews: 1 star hotel
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The track at Miller Motorsports Park is a 4.5-mile, 40-50 foot wide, 24-turn circuit, the longest in North America. It has four different configurations, ranging from two different 2.2-mile circuits (East and West Courses) to the 3.08-mile Perimeter Course and the 4.5-mile Full Course. The 3500-foot main straightaway allows the fastest cars and motorcycles to approach 200 mph before braking for Turn 1. The 511-acre facility also boasts a 0.9-mile paved karting circuit, one of the finest in the country, with 20 different configurations available.
Miller Motorsports Park is a state-of-the-art road racing facility for automobiles, motorcycles and karts located just 35 minutes from downtown Salt Lake City in Tooele, Utah. It is considered the finest facility of its type in North America. Opened in 2006, Miller Motorsports Park hosts many of the world's most significant racing series, including the American Le Mans Series, Grand-Am Rolex Sports Car Series, NASCAR Grand National West Series, AMA Superbike Championship and, new for 2008, the FIM SUPERBIKE WORLD CHAMPIONSHIP, one of the top three racing series in the world.
In addition to the professional racing series that visit Miller Motorsports Park, the track also has its own locally-based racing series for road racing cars and motorcycles, Supermoto motorcycles and karts (with competitor's ages ranging from five to 65 years old). There is racing taking place almost every weekend between April and October.
Miller Motorsports Park is the most advanced, safest and best-equipped road racing facility in North America. So outstanding was its design and execution that it was named "Motorsports Facility of the Year" by the Professional Motorsport World Expo in Cologne, Germany, on November 8, 2006. The facility offers something for everyone, with outstanding fan amenities, unmatched corporate meeting and entertainment options and the finest paddock and garages available for teams. Miller Motorsports Park is a significant addition to the national road racing industry, and a major component of the ever-growing Salt Lake City sporting market.
Miller Motorsports Park is situated in Tooele County, just 25 minutes from Salt Lake City International Airport, 35 minutes of downtown Salt Lake and about 10 minutes from Tooele or Grantsville. It is directly adjacent to Tooele County's Deseret Peak Recreation Complex. Miller Motorsports Park is easily accessed by major highways (I-80) and surrounding county roads.
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I've stayed there twice in the last year and found the accommodations both comfortable and very clean. The rooms are well-kept and attractive. All rooms have a mini-fridge and microwave which I need since everything closes early up in the North Country so I can eat when I need to. The owners are very accommodating and attentive to your needs.... More
- Also Known As:
- Sara-Placid Motor Hotel Saranac Lake
- Sara-Placid Motor Hotel
- Sara Placid Hotel
- Official Description (provided by the hotel):
- Beautiful lake/mountain setting. Motel rooms, kitchenettes, housekeeping apartments, suites with private bedrooms, Jacuzzi Suite, bed and breakfast type accommodations and three lakefront cottages. ... more less


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Email Richard at: firstname.lastname@example.com Material ©2013 Richard Herring Skin Selector
The Times (London)
January 5, 2011 Wednesday
Edition 1;
National Edition
Richard Herring;
BYLINE: Clive Davis
SECTION: T2;FEATURES; Pg. 15
LENGTH: 362 words
Leicester Square Theatre, WC2 ***
Have you heard the one about the comedian and the Bible? No doubt you have, since deconstructing religion has become one of the most familiar gambits in the stand-up trade. Tim Minchin turned the elements of militant Dawkinism into a foot-tapping tune on his recent stadium tour, while every other comic on the block can supply a decent explanation of why, as they see it, going to church wastes time that could be better spent at the pub. (I exaggerate, but only just.) What was daring in the days of Life of Brian is conventional now.
Still, although Richard Herring is treading a well-worn path, few acts explore the theme of faith versus dogma with quite as much intelligence and wit. Christ on a Bike: The Second Coming, an updated version of a show that he first performed a decade ago, offers an ingenious blend of fantasy and autobiography.
The passages devoted to his mildly eccentric West Country childhood have genuine poignancy about them and his mischievous textual analysis of the Gospels of Matthew and Luke generates the funniest lines of the night. If he sometimes opts for soft targets, he casts a shrewd eye over issues of authenticity. Even a devout believer would surely have to concede that he makes some persuasive points about the internal logic of the Ten Commandments.
Those moments make the occasional lapse into puerile willy jokes seem all the more glaring. As with his last show, devoted to the mysteries of Hitler's moustache, the script sags before the close and his summing-up, which attempts to equate belief in God with belief in democracy, would probably not even get past the gatekeepers on Thought for the Day.
Herring's delivery also has a touch of the soapbox about it - he is too fond of haranguing listeners who, to judge by the show of hands at the end, already share his opinion of the historical accuracy of the Gospels or the Pope's stint in the Hitler Youth. Fortunately, he is still open to self-doubt. Given that his parents are believers, would it really give him any satisfaction, he wonders, to convert them to his brand of atheism? Probably not.
Clive Davis
Box office 0844 8733433; to Jan 22
Bottom of Form


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The Castle Upton Gallery held our Annual Exhibition on 10th December and despite the extreme weather conditions and battles with snow, ice and fog there was an exceptionally good turnout and positive sales. There was a mixture of established gallery artists such as Barbara Allen, Josephine Kelly and Melita Denaro as well as new artists such as Ailsa Friel with her contemporary take on Donegal landscapes and Rory Bullock with his dreamlike figurative work.
We want to thank all of our clients and friends for their support in the past year, and look forward to the year ahead.
December 2010
A new and varied selection of paintings previously displayed at the opening of the new offices of Belfast stockbroker firm Cunningham Coates, and now on display in the Refectory Gallery in Castle Upton.