Objective To investigate the diagnosis and management of acute mesenteric venous thrombosis(AMVT).Methods A historically controlled analysis was conducted in the clinical data of 13 AMVT patients from July 1995 to September 2002 undergoing surgery-based therapy(group A) and 14 AMVT patients from January 2003 to September 2010 undergoing anticoagulant thrombolytic-based therapy(group B).The length of hospital stay,cure rate and mortality between the two groups were compared.Results The length of hospital stay,cure rate and mortality of group A was(22.38±2.81) days,69.2% and 30.8%;and that of group B was(12.21±2.32) days,100% and 0,respectively.The differences of all the above mentioned parameters between the two groups were statistically significant(P0.05 or P0.01).Conclusions Early diagnosis and aggressive therapy with anticoagulants and thrombolytics can increase the cure rate of AMVT,and are also the key faetors to improving the prognosis of this disease.


The thermo-micropolar non-Newtonian theory is used to formulate a transport model for combined free convection heat and species transfer through a micropolar-fluid saturated Darcian porous medium. Temperatures in the medium are assumed to be high enough for viscous heating effects to be significant. The influence of thermal Grashof number, species Grashof number and Darcian porous number on the momentum, angular momentum, temperature and concentration flow fields are studied using the finite element method. Temperature is observed to be reduced with a rise in the thermal Grashof number. Species transfer is seen to be also decreased with increasing species Grashof number. Micro-rotation values are also decreased with both thermal and species Grashof numbers near the stretching surface and also depressed with a rise in the Darcy number in the near-field regime. The flow field is accelerated with a rise in Darcy number as indicated by the increase in translational velocities. Our computations are relevant to for example the diffusion of hydrogen gas in air-saturated porous materials, pollutant release in a geophysical regime etc.


A new family of six mononuclear indium(III) complexes of formula mer-[InIIICl3(pz*H)3]-pz*H = pyrazole (pzH), or substituted pyrazoles: 4-Cl-pzH, 4-Br-pzH, 4-I-pzH, 4-Ph-pzH and 3,5-Me2-pzH-were synthesized by addition reactions of InCl3 and pz*H and crystallographically characterized. The fluxional behaviour of the complexes, probed by variable temperature 1H NMR spectroscopy in the 328 K to 173 K range, was attributed to (at least) four simultaneous processes: pyrazole N-H proton dissociation/association, cis/trans-pyrazole exchange, and N1/N2 tautomerization of the cis- and of the trans-pyrazoles. Three novel trianionic hexanuclear complexes of general formula (pipH)3[In6Cl6(μ3-OH0.5)2(μ-OH)6(μ-pz*)6]-pz* = pz, 4-Cl-pz and 4-Ph-pz-showing μ-hydroxo and μ-oxo bridges were synthesized from the corresponding mer-[InIIICl3(pz*H)3] and characterized by single crystal X-ray diffraction and 1H NMR. Under different solvent conditions, multicolour emitting polymeric complexes of general formula [In(μ-pz*)3]n-pz* = pz, 4-Cl-pz, 4-I-pz and 4-Ph-pz-were obtained also from mer-[InIIICl3(pz*H)3] after addition of a base. Luminescence and lifetime calculations were performed for all polymers formed.


The N-methyl-N-propyl, N-methyl-N-isopropy, N-butyl, N-isobutyl, N-sec-butyl and N-tert-butyl amides of lysergic acid were synthesized to determine the specificity of electron impact mass spectroscopy (EI/MS), when combined with other analytical techniques, for the identification of lysergic acid diethylamide (LSD). After separation of the C8 axial and equatorial isomers by preparative thin-layer chromatography, the amides were subjected to gas-liquid chromatography (GLC), thin-layer chromatography (TLC), high pressure liquid chromatography (HPLC), and EI/MS. EI/MS, when combined with other analytical techniques, is shown to be capable of differentiating LSD from any of the other compounds included in this study.


The family institution is one of the most important social institutions that begin with marriage, so marriage has a fundamental and fundamental importance since the foundation's opening ceremony, and the foundation of the family is laid in marriage. If the marriage is successful, it helps a lot in psychosocial development. The success of marriage depends on the level of readiness of individuals for marriage and their realistic understanding of marital relationships. Couples' relationship has unique characteristics that awareness and acceptance of these characteristics by the couple can contribute to the success of marriage (Nazari, 2007). It is not advisable to achieve mutual maturity in marriage and marital satisfaction in most cases, but with regard to factors affecting marital satisfaction, we can expect that by increasing the level of marital satisfaction and mental health, many psychological, emotional and social problems (Mazarei, 2009). The description of the obsessive-compulsive disorder since its inception, by Scirol (1838) has not changed so far. This disorder is introduced with various titles such as obsessive compulsive disorder, Norouz or obsessive compulsive disorder and obsessive-compulsive disorder. Obsessive-compulsive disorder or obsessive-compulsive disorder is determined by intrusive thoughts, mental images and compulsive behaviors. Mandatory practices include obvious rituals (such as frequent washing of hands & checking behaviors) and subtle rituals; These two types of ritual are considered here as despicable behaviors. Revised Text The fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM IV-TR) defines obsessive-compulsive disorder as recognizing the predictive ways that differs from over-concern concerns about real life issues. This refers to the differentiation of obsessive-compulsive thoughts from the concerns that are common in anxiety disorder.Problem statementThe study of the history of mental disorders shows that these disorders have always been and are human beings, and humans resort to appropriate and inappropriate ways to prevent and treat it. One of these disorders is obsessive-compulsive disorder (OCD), which has an adverse effect on the psychosocial and economic performance of the individual and even the family, especially marital satisfaction. Obsessive-Compulsive Disorder (OCD): An OCD is a chronic anxiety disorder that is associated with extreme mental employment in the order and the affairs, as well as in perfection, to a degree that results in loss of flexibility, clarity, and efficiency (Kaplan & Saduk, 2010). Another definition of this disorder is that obsessive-compulsive disorder (OCD) is a common heterogeneous mental disorder with thoughts and actions. Obsessive compulsive disorder involves disturbing thoughts, recurrences, and unwanted continuous thoughts.Statistical societyThe statistical population of this study included all paired individuals with obsessive-compulsive disorder referring to Shiraz clinics in 2014.MethodThe present research is based on descriptive-cross-sectional research with respect to its objectives and its nature, using correlation method in the form of a pre-design.ParticipantsIn this research, 60 people who referred to health centers were selected using purposeful sampling method. They were selected based on a questionnaire, structured clinical interview and obsessive-compulsory psychiatrist's opinion. Referring to psychiatric centers, Hafez Hospital and Imam Reza Clinic (AS) their statistics were reviewed.Information gathering toolEnrich Marital Satisfaction Inventory (1989): This questionnaire has been used as a valid research tool in numerous surveys to measure marital satisfaction.Information gathering toolEnrich Marital Satisfaction Inventory (1989): This questionnaire has been used as a valid research tool in numerous surveys to measure marital satisfaction. …


OBJECTIVE To study the effect of Amomum villosum on functional digestion disorder in rats.METHODS All 30 Wistar rats were randomly divided into control group,model group and Amomum villosum group.The gastric motility changes of rats were assayed by Dextran blue-2000 as an indicator;contents of motilin(MTL),substance P(SP)in plasma,antral tissue were detected with radioimmunoassay.RESULTS Compared with control group,the gastric motility in model group was markedly delayed(P0.01) and the contents of MTL and SP were markedly decreased in plasma and antral tissue(P0.05),but the gastric motility and the contents of MTL and SP had no significant difference(P0.05) after treatment with Amomum villosum.CONCLUSION The improving effects of Amomum villosum on functional digestion disorder in rats may be corelated to the increased contents of MTL and SP in plasma and antral tissue.


The explosive growth of the web and the increased number of users have led more and more organizations to put their information on the web and provide sophisticated web based services such as social networking, e – leaning, Internet banking, on-line shopping etc. However, the continuous growth in the size and use of the web is increasing the difficulties in managing the web content. Thus, an urgent need exists for developing new techniques in order to improve the web performance. In this context, cluster analysis can be considered as one of the most important aspects in the web mining process for discovering meaningful groups. This article aims to report a technique that involves the identification of the web user sessions and then clustering these sessions based on certain criteria to result into a faster internet access.


Abstract
Purpose: Severe stress is significantly involved in heart attack and raises the amount of disease and mortality. In addition, there is evidence that specific treatment for severe stress can have a positive impact on the treatment results. Cardiovascular diseases are one of the most important research subjects study psychological and behavioral factors on health.
Methods: This research is an experimental one with pre test- post test design and experimental and control groups with randomly assigned 36 patients in experimental and control groups. The present aims at testing the effect of eight, 2-hour sessions of stress management training based on cognitive behavioral techniques. Subjects were tested at the beginning and at the end of the project with beck depression inventory primary care, beck anxiety inventory and depression, anxiety, stress scales. The data was analyses via covariance analysis test.
Results: Mean(average) scores showed significant.(31.83 in experimental group and 17.94 in control group). Study findings showed that the subjects of experimental group that were under the intervention(training) compared with control group showed significantly better scores and test effectiveness.
Conclusion: The subjects of the present study were homogenious in terms of age, education and socio- economic status. They were both males and females equally as well. Therefore it can be concluded that various factors affecting the dependent variables were highly controlled and therefore the observed effect on the dependent variables could be the result of the interference imposed, which is the "stress management training". The effectiveness of group interference of cognitive behavioral aspects of stress management on depression, anxiety and stress of cardiovascular patients was with in the present study. Finally the presence of a psychological within the treatment team of cardiac patients is suggested on a critical factor and recommended.

1.M.A, in general psychology Email: email@example.com
2.Ph.D of Health psychology
3.Cardiologyst


We replicated a program to increase indices of happiness among people with profound multiple disabilities and conducted a component analysis of the program. The program involved presentation and contingent withdrawal of stimuli that had been identified as preferred based on preference assessments and staff opinion. The program was implemented with 3 adult students and was accompanied by increased happiness indices for each student. Subsequent implementation of the two types of stimuli indicated that preferred stimuli based on preference assessments were more consistently accompanied by increased happiness indices than were preferred stimuli based on staff opinion. Social validity measures supported the definition of happiness, in that raters' subjective opinions of the students' happiness coincided with the observed happiness indices. Results are discussed regarding the importance and practical implications of using preference assessments for determining stimuli for increasing happiness indices. Future research areas are suggested, focusing on increasing happiness and other quality-of-life indicators during the daily routines of people with profound disabilities. DESCRIPTORS: happiness, profound multiple disabilities, quality of life An area of increasing concern in developmental disabilities is ensuring that individuals experience enjoyment or happiness with certain aspects of their lives. The importance of assisting people with developmental disabilities to acquire an enjoyable quality of life has been discussed frequently (see Felce & Perry, 1995, for a review). Likewise, regulatory standards for agencies that provide supports for people with developmental disabilities have begun to emphasize individual enjoyment and fun experiences as important outcomes of desired agency practices (HCFA, 1996).


Objective: Research on the compositions of phenolic acids and flavanone glycosides and antioxidant capacity in ponkan and satsuma mandarin peels. Methods: The contents of nine phenolic acids and two flavanone glycosides in ponkan and satsuma mandarin peels were determined by RP-HPLC method. Folin-Ciocalteu method, ABTS free radical-scavenging assay and FRAP assay were adopted to evaluate the antioxidant capacity of methanol extract of citrus peels. Results: The soluble esterified portion is the most common form of phenolic acid in citrus peels. Phenolic acids of citrus peels mainly occurr as hydroxycinnamic acid and the contents are in the following order: ferulic acid p-coumaric acid sinapic acid caffeic acid. peels of satsuma mandarin show higher total phenolic acid content than ponkan (p0.05). Peels of ponkan was abundant in hesperidin, while peels of satsuma mandarin have higher content of narirutin compared with ponkan. Peels of satsuma mandarin contain higher contents of total flavanone glycosides than ponkan (p0.05). Generally speaking, ponkan extract shows higher antioxidant capacity than satsuma mandarin. Conclusion: Good results are obtained by using HPLC-PDA method to determine the contents of phenolic acids and flavanone glycosides, while citrus peels present certain antioxidant capacity evaluated by several antioxi- dant assays.


Background and Aim: Breast and cervical cancer screening is considered a health promotion behavior, influenced by complex factors. The theory of planned behavior provides a useful framework for predicting and understanding the health behavior and designing appropriate educational interventions. Integrating this theory with self-efficacy will increase its predictive value. The objective of this qualitative research project was to understand the factors influencing the behavior of breast and cervical cancer screening of female-workers as a base for future educational planning. Materials and Methods : Seventy 20-45 year-old women working in industrial plants in Abbasabad, Pakdasht, selected by purposeful sampling with maximum diversity participated, in 10 groups of 7 each, in focus-group discussions, in which they discussed their experience regarding factors influencing the behavior of breast and cervical cancer screening. Data were collected and their validity, conformability, transferability and dependability confirmed. For data analysis the conventional method of content analysis was used. Results: The female workers had a low knowledge and attitude concerning the behavior of breast and cervical cancer screening . Attaching importance to comments given by the family members , especially the husband, and preference of treatment to prevention of disease in the society at large the subjective norms of the female workers. The most important barriers to participating in screening programs were lack of knowledge, depression, fatigue, embarrassment and fear of examinations, fear of being sick, poor quality of services and lack of attention to privacy in health centers, limited access to health centers, and costs of tests.


The demand for blood donation makes it a constant activity, whereby knowing the motivational aspects for its implementation becomes a determinant in the formulation of strategies for the increase of donors and to strengthen the donation programs. The aim of this study was to establish the main motivations for voluntary donation in the population that attended a gathering point of Bogota (Colombia). A descriptive transversal study was designed with a sample of 500 adults (28.8 ± 10.4 years), 58% female. A survey was done for data collection. The variables used were age, sex, socioeconomic status, residence for the last five years and main motive for blood donating. A descriptive and a bivariate analysis applying the chi2 test were ejecuted. The software used was Stata 11.0. The main motives for donation were the promotion (18% CI 95% 14.7-21.7) and to save lives (14.4% CI 95% 11.4-17.8). People coming from socioeconomic levels I and II donated mainly motivated by the promotion (33.0%) and those from the socioeconomic levels III, IV and V donated mainly to save lives (38.4%). The interviewed population gave clear information about the aspects that motivated voluntarily and willingly blood donation, as to promote more donations and save lives, among others.


Holding device (1), in particular adhesion gripper, with a holder (2) and a gripping punch (3) fastened in or on the holder (2), wherein the gripping punch (3) consists of a single-phase plastic body with an elastomeric contact surface (4) the gripping punch (3) and its contact surface (4) consists of a crosslinked with a crosslinking siloxane.


Purpose – The purpose of this paper is to examine whether working environments possessing characteristics of a complex adaptive systems (CAS), such as organizational social networks (SNs), will be perceived by the individual worker as contributing to working efficiency. The author tested whether SNs increase the workers' sharing of knowledge, sensitivity to environmental changes and synchronization of resource, which contribute to the autonomic ability to create solutions according to changing demands in turbulent environments.Design/methodology/approach – A research questionnaire distributed online assessed the views and behaviors of 94 subjects regarding SNs. An index was formed for each of the four CAS variables (Goal compliance; Situational sensitivity; Integration of information; and Resource synchronization) to evaluate how the subjects perceive SN effectiveness.Findings – A significant positive correlation was found between the degree of contribution to organizational working processes and the vari...


In New Mexico, the mortality rate due to diabetes is 1.5 times higher than the nation. Diabetes causes a huge healthcare burden. In 2012, the national cost due to diabetes was $245 billion. Prior studies have established a positive correlation between vitamin D deficiency and diabetes; whether the same relationship holds for prediabetes is not well studied. Our purpose of the study was to find whether there was an association between vitamin D deficiency and prediabetes. We also wanted to find out if the association was stronger among Hispanics than non-Hispanic whites (NHW). Our rationale was to delay the progression of diabetes by preventing at a prediabetes stage with vitamin D supplementation in deficient population. In New Mexico, there are 106,310 adults diagnosed with prediabetes which is 7% of our population. Therefore, it is crucial that a preventive measure is in place to impede the progression of diabetes among a vulnerable population where there is a high rate of diabetes, obesity and vitamin D deficiency.


Work with motivation. Be aware of the disadvantages of addictive behaviors for the body and mind, unpleasant experiences from the past and possible problems that can come in future. We can recall awkward feelings and states of exhaustion, or we can realize that the internet is not that anonymous. The network administrator at work or your family members can easily find out which web pages you visited and what you did there.


This paper reports the levels of stress experienced by registered and student nurses in a large metropolitan teaching hospital. A scale measure of current stress was developed and its psychometric properties assessed. Similar scale measures were constructed for the independent variables: nurses' personal attributes and perceived stressors. There was a symmetric distribution of stress scores and further analyses focused on the approximate 30% of nurses at the "high stress" end of the scale, assumed to be experiencing excessive stress. High stress was strongly associated with feeling poorly, poor self-worth, dissatisfaction with social supports, feeling worse as pressure builds up and dissatisfaction with own coping. The particular stressors affecting registered and student nurses, respectively, were identified.

In addition, lack of responsiveness of the nursing and medical managements affected stress among Registered Nurses (RN's), while lack of status in the medical team and job overload were significant stressors of Student Nurses (SN's). The risk of being highly stressed, given the presence of various personal attributes and job stressors, was estimated using logistic regression. Stress levels in different areas of the hospital were compared, and the personal and job stressor factors that most accounted for the high levels of stress in different areas were identified.


The concrete crack is a common and hard-solve problem in engineering practice, and the concrete crack should not be neglected, otherwise, there would be huge safe hidden danger in architecture engineering. As result, this paper discussed and analyzed some usual crack problems in concrete engineering and put forward some preventive treatments to specific circumstances.


Constant-pressure first-principles molecular-dynamics simulations were carried out to study structural and electronic properties of the polymeric phase of liquid phosphorus at high pressures. It is found that, around 1 GPa, atoms are connected by covalent bonds by p electrons and accompany a Peierls distortion as in liquid arsenic. This liquid structure reflects the rhombohedral (A7) structure of crystalline phosphorus in local atomic configurations. Further compression increases the number of the first nearest neighbors and reduces the Peierls distortion. It is considered that the reduction of the Peierls distortion in the liquid phase is closely related to the transition from the A7 to simple cubic structures in crystalline phases. The characteristics of liquid phosphorus around 25 GPa and over are similar to those of liquid antimony and bismuth.


Lycopene is the red pigment richly found in many red -colored fruits and vegetables such as tomatoes, papaya, pink grapefruit, pink guava, and watermelon. It is an antioxidant that has various beneficent effects and protects against oxidative damage to lipids, protein, and DNA. It is a potent quencher of oxygen and most effective against cancer, cardiovascular diseases, osteoporosis, hypertension, male infertility, and neurodegenerative disease. Lycopene is synthesized by plants and microorganisms but not animals and humans. The main objective of this study is to develop and validate an HPLC assay method for the determination of lycopene in tomato, watermelon, and human blood. A simple assay method is an economical assay method, suitable for the determination of lycopene from plant and biological sources. A new accurate, specific, precise, high performance liquid chromatographic (HPLC) method has been developed and validated for the determination of lycopene in tomatoes, watermelon and blood sample according to the International Conference on Harmonization (ICH) guidelines. Acetonitrile, Methanol, Water (65%, 20%, and 15%) was used as the mobile phase at a flow rate of 0.7ml/min. using a symmetry C18 column. The effluent was spectrophotometrically monitored at 484nm. The calibration curve was linear with a correlation coefficient of 0.9994. The average recovery was found to be 102.0%. The proposed HPLC method was successfully applied to quantify the amount of lycopene in different matrices.


Objective To investigate the therapeutic effect on the artificial humeral head replacement for comminuted fractures of the proximal humerus in the elderly.Methods 17 patients with comminuted fractures of the proximal humerus in the elderly were treated with artificial humeral head replacement,9 cases of three-part fractures and 8 cases of four-part fractures,according to Neer classification of fractures of the proximal humerus.Results Twelve patients were followed up for 6~24 months,at an average of 12 months.The range of shoulder joint motion: anteflexion and superduct 110°,abduction 70°,extorsion 30°.According to the Neer score of shoulder joint function,9 cases were graded as excellent,5 as good,2 as fair,and 1 as poor.Conclusion Treatment of comminuted fractures of the proximal humerus in the elderly with artificial humeral head replacement has operative time,quick recovery of function and satisfactory short-term results.


We propose two new methods for wideband array signal imaging for targets situated in unknown random media. First, a normalized coherent interferometric (N-CINT) imaging algorithm is developed based on coherent interferometric (CINT) imaging theory, yielding improved imaging performance with experimental data. Second, a phase-difference analysis (PDA) method is proposed to significantly reduce computation time and to improve imaging quality. The parameters in the two methods are determined adaptively by optimizing an objective function. Experiments are carried out for electromagnetic scattering using a linear antenna array, providing a demonstration of these methods.


One approach for the identification of therapeutic agents for Alzheimer's disease has focused on the research of a7 nAChR-selective agonists such as the partial agonists 3-(4-hydroxy,2-methoxybenzylidene)anabaseine (4OH-GTS-21) and, more recently, 2-[2-(4-bromophenyl)-2-oxoethyl]-1methyl pyridinium (S 24795). An alternative approach for targeting a7 nAChR has been the development of positive modulators for this receptor. In this study we examined the interactions between full or partial agonists and positive modulators of a7 nAChRs in situ in brain tissue. Three positive modulators were used, 5-hydroxyindole (5-HI), 1-(5-chloro-2,4-dimethoxy-phenyl)-3-(5-methyl-isoxanol-3-yl)-urea (PNU-120596), and genistein. Whole-cell recordings were performed in stratum radiatum interneurons from rat brain slices. Hippocampal interneurons were stimulated by ACh, choline, S 24795, or 4OH-GTS21, before and after bath perfusion with the positive modulators. 5-HI was not effective at potentiating 200 mM 4OH-GTS-21-evoked responses, however 5-HI induced a sustained potentiation of responses evoked by 30 mM 4OH-GTS-21. When 1 mM ACh and 200 mM 4OH-GTS-21 were applied alternately a7-mediated responses to both agonists were reduced, suggesting that high concentration of 4OH-GTS21 produces residual inhibition or desensitization and that 5-HI is not effective at overcoming receptor desensitization. Similar results were obtained with a7 receptors expressed in Xenopus oocytes. Interestingly, responses evoked by S 24795 were potentiated by 5-HI but not by genistein. Additionally, PNU120596 was able to potentiate a7-mediated responses, regardless of the nature of the agonist. We demonstrated that the potentiation of a7 nAChR response would depend on the nature and the effective concentration of the agonist involved and its particular interaction with the positive modulator. 2009 Elsevier Ltd. All rights reserved.


The surface waters of the Kurow-Duntroon irrigation area are of low salinity. Except for a very restricted area the ground water is also of low salinity and is at too great a depth to cause soil salinisation problems as a result of irrigation. Leaching of the few saline areas should be possible with controlled irrigation.


Neutron superfluid dynamics and the coupling between the superfluid and the solid crust play important roles in the rotational, thermal and magnetic evolution of neutron stars. Here we describe the physical processes by which the neutron superfluid and the crust interact.


This dissertation addresses issues of scheduling, state-operations and actor granularity for data-driven and hybrid data-driven/control-driven systems. We propose block scheduling techniques for iterative algorithms and a graph-level priority mechanism for loop-based algorithms. A general framework has been developed for incorporating general purpose Input/Output operations in the dynamic data-flow environment. Variable resolution graphs are introduced which retain the dynamic data-flow principles of execution at the coarser level and employ control level at the finer level. We have also proposed and developed the Decoupled Graph Computation (DGC) model of execution and architecture.
The block scheduling techniques enable the dynamic interpreter to unravel a block of n iterations instead of merely one and thus, exploit parallelism across successive iterations. A look-ahead estimator, based on the observed convergence rate of the algorithm, calculates the optimal block sizes at execution time. A graph-level priority scheduling mechanism has been developed that favors early iterations. This improves resource utilization and yields higher performance.
The very asynchronous nature of the data-flow model of execution introduces conflicts when "state" tasks (such as I/O operations) must share common data objects. In order to execute I/O operations safely and in parallel, an algorithm to detect and classify cases of potential conflicts (hazards) has been developed. It is based upon localizing the effect of I/O operations by splitting the data-flow graph into two subgraphs: (a) the computation subgraph, and (b) the I/O subgraph. The scheme presented here enables the creation and interaction of both subgraphs, which in turn yields a deterministic execution. Furthermore, a distributed file-pointers scheme has been adopted that enables the parallel execution of I/O operations as permitted by data dependencies.
We have also developed a hybrid multiprocessor architecture that combines the advantages of the dynamic data-flow principles of execution with those of the control-flow model of execution. Two major design ideas are utilized by the proposed model: decoupled execution of graph and computation operations, and variable-resolution actors. The independence of the two main units of the machine allows an efficient implementation of functional/data-flow principles with conventional, mature technology and reduces the latency penalty incurred due to the graph (overhead) operations. The compiler generates graphs with variable-sized actors that exploit locality and matches the characteristics of the application to the target machine. (Copies available exclusively from Micrographics Department, Doheny Library, USC, Los Angeles, CA 90089-0182.)


This article mainly introduced the design and application of a contactless liquid switch, It described the component and de- sign detail of the contactless liquid switch circuit, which is based the principle of capacity theory and high frequency theory, and it emphasized the cheapness, credibility and simpleness of the contactless liquid switch. The application case and results of the contact- less liquid switch were given finally.


The last IEEE Communications Magazine Feature Topic related to disaster was published in January 2011 under the title "Network Disaster Recovery," where various discussions on disaster prevention and rapid recovery were discussed from technological and managerial points of views.


1Mendel Centre for Genomics and Proteomics of Plants Systems, CEITEC MU Central European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic 2Department of Plant Systems Biology, Flanders Institute for Biotechnology (VIB) and Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium 3BIOSS Centre for Biological Signaling Studies, Faculty of Biology, Albert-Ludwigs-Universitaet Freiburg, 79104 Freiburg, Germany 4Department of Genetics, Faculty of Biology and Environmental Protection, University of Silesia, 40-032 Katowice, Poland 5Laboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science of Palacký University & Institute of Experimental Botany CAS, 783 71 Olomouc, Czech Republic 6Cell Biology and Plant Biochemistry, Biochemie-Zentrum Regensburg, University of Regensburg, 93053 Regensburg, Germany 7Institute of Science and Technology Austria (IST Austria), 3400 Klosterneuburg, Austria


During the course of a comparative study of media for isolation of Mycobacterium tuberculosis from sputum and other infectious material, it was decided to attempt culture of this organism in eggs. This was prompted by the observation that cultural methods now used for this purpose prescribe media containing whole eggs or egg yolk and because of the successful cultivation of viruses and bacteria on the chorioallantoic membrane of the developing egg. The developing egg has been used by Brandly and Graham 1 and Bradford and Tittsler 2 for the culture of bacteria. The former authors obtained growth of Brucella, Salmonella and Pasteurella species upon the chorioallantoic membrane of developing eggs and the latter cultured Neisseria gonorrhoea in the developing egg. Although these authors were studying the invasive powers or pathogenicity of the inoculated organisms their observations are of interest. Bradford and Tittsler suggest the method as a means of culturing Neisseria gonorrhoeα from sources such as joint fluid. In the present study the primary object was cultivation of the organism from infected material in the simplest and quickest manner possible. The egg of the chicken was used with no attempt to obtain a developing embryo. As a preliminary experiment, a suspension of a pure culture of freshly isolated Mycobacterium tuberculosis was injected into the yolks of fresh eggs. The egg shell was sterilized with 5% phenol followed with 95% alcohol and then pierced with a sterile pin. The suspension of Mycobacterium tuberculosis was then inoculated (1/2 cc.) into the yolk of the egg and the pin hole covered with a drop of paraffin. The egg was then placed in the 37°C. incubator and incubated for 20 days. After incubation the egg was broken and the contents were placed in a sterile Petri dish.


The following is a description of a new species of Odax,
caught in the waters of the Derwent, and presented to Mr. R.M. Johnston by
Captain Beddome.


Recently published whole exome sequencing studies in head and neck squamous cell carcinoma (HNSCC) tumors revealed that few had therapeutically targetable alterations using current strategies. This finding defines translational gap between genomics and HNSCC treatment. One potential targetable alteration is PIK3CA mutations. However, clinical trials testing PI3K/mTOR pathway inhibitors have had limited success and these inhibitors only lead to cell cycle arrest in PIK3CA mutant HNSCC cell lines. Thus, there is a critical need to identify therapeutic vulnerabilities for common mutation groups, including tumor suppressors, in HNSCC. One of these molecular subgroups is NOTCH1 which is the second most frequently mutated gene in HNSCC, with a 10-15% prevalence of inactivating mutations. Although there are several studies underscoring the importance of NOTCH1 as a tumor suppressor in HNSCC, none has identified a therapy that targets NOTCH1 mutant (mut) HNSCC. Our objective was to identify predictive biomarkers of sensitivity to PI3K/mTOR inhibitors by integrating drug and multiple-omics data. Cell viability with six PI3K/mTOR inhibitors in 68 HNSCC lines was measured by the CellTiter Glo assay. The peak plasma concentration of each drug was used as the cut-off to determine sensitivity. We observed a striking correlation between NOTCH1mut and sensitivity to PI3K/mTOR pathway inhibitors. When fisher9s exact test was performed, NOTCH1mut lines were more sensitive to GSK2126458 (P NOTCH1mut lines underwent more apoptosis after GSK2126458 treatment compared to NOTCH1wt lines (PCI15B- 48.1 fold; P Our data suggests that loss of active NOTCH1 signaling confers sensitivity to PI3K/mTOR inhibition. If the combination of NOTCH1 and PI3K/mTOR inhibition leads to apoptosis, this combination could be translated into the clinic. Citation Format: Faye M. Johnson, Vaishnavi Sambandam, Li Shen, Ming Zhang, Rishi Saigal, Pan Tong, Tuhina Mazumdar, Lauren A. Byers, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Mitchell Frederick. NOTCH1 inactivating mutation mediates sensitivity to PI3K/mTOR inhibitors in head and neck squamous cell carcinoma. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 393.


System (1) treatment of exhaust air, in particular for kitchens, with at least one part (2) supporting and at least one part (3) removable housing is arranged or can be arranged in the part (2) supporting part (3) of housing during operation of the system (1) treatment of exhaust air is passed through or can be passed through by air extraction, and part (3) of housing in which it is disposed at least one UV (4) unity which can be applied electromagnetic radiation in the UV range to exhaust air, being provided in the part (2) supporting and part (3) housing together at least one device ( 5) electrical contact, wherein the device (5) electrical contact includes: a first support (6) contact with a first amount of first elements (7) contact; a second support (8) contact with a second quantity of second items (9) contact; and a device (10) of spring force is arranged to act on the second support (8) contact; It is arranged at least a partial amount of the first elements (7) contact or the second elements (9) contact so that they are in contact or can contact electrically conductive in pairs in each case together with a contact element of another contact support, in a connected state of the contact device, form pairs of contact elements; being configured first elements (7) contact or the second elements (9) contact as spring contacts, whose tips, at least one unconnected state of the device (5) contact protruding to an extent in excess (UM ) above a surface (6a) of the contact carrier (6) corresponding surface (6a) which is oriented towards the other support (8) contact, at least in the connected state; It is applied or may be applied by the device (10) of spring force a force (F) spring on the second support (8) contact toward the first support (6) of contacts when they are formed such element pairs Contact; the first support (6) contact essentially non-displaceably in a first device (2) supporting, first device (2) supporting which is arranged in the part (2) supporting or that is formed being held by said part (2) support; the second support (8) contact on a second device (3) support being subject and being movable in the same with respect to this second device (3) support against the force (F) applied or applicable dock by device (10) of spring force, the second device (3) supporting which is arranged in the part (3) or casing is formed by said portion (3) housing; and achieving the connected state of the contact device when the portion (3) disposed in the housing part (2) of lift.


In the title compounds, [Co(C 2 O 4 )(CH 5 N)) 4 ]ClO 4 (1), and [Co(C 2 O 4 )(C 2 H 7 N) 4 ]ClO 4 .H 2 O, (2), the Co atom has a distorted octahedral coordination composed of four amine ligands and one oxalato ligand. The coordination and oxalato bond distances in (1) and (2) are similar to the corresponding distances in [Co(C 2 O 4 )(NH 3 ) 4 ] + . The Co-N-C angles are in the range 117.1 (4)-123.2 (2)°.


The effectiveness of three common nematocides was studied for the control of the root-knot nematode (Meloidogyne incognita) by first screening on potted (brinjal plants and then testing the promising chemical doses combination on brinjal and tomato in the field. In the pot experiment, the treatments tested were D-D mixture (100 per cent) at 112.33, 168.50, 224.66 280.82 and 336.99 L AI/ha as pre-plant soil injection, DBCP (Nemagon 60 per cent) at 6.73, 13.46, 20.19, 26.92 and 33.65 L AI/ha as post-plant soil drench followed by irrigation; and phorate (Thimet 10 per cent granules) at 1.24, 2.47, 3.70, 4.94 and 7.41 kg AI/ha applied by broadcasting in final stages of preparatory tillage. On the basis of larval population and galling index, the three higher doses of D-D mixture and DBCP, and the three middle doses of phorate were selected for the field tests.


An attenuation control device for attenuating a high-frequency wave signal is used in a high-frequency wave signal reception device, and is provided with a calculator which outputs digital data for controlling an attenuation amount of the high-frequency wave signal, and a DA converter which performs DA conversion of the digital data into a control current which controls a current flowing in a PIN diode for attenuating the high-frequency wave signal, wherein the DA converter outputs an analog current as the control current, the analog current being corrected so that a logarithmic value of the attenuation amount of the high-frequency wave signal becomes substantially linear with respect to the digital data.


The converse inequality of Markov type is discussed in this note. The main result says that the best possible constant for this inequality is the square root of the least eigenvalue of a certain positive definite matrix. As applications of the main result, the Laguerre weight and Hermite weight are investigated in detail, and the best constants in these two cases are obtained explicitly.


A robust segmentation and boundary tracking technique for the extraction of the region and boundary of mammalian cells in bioelectric images is presented. The proposed algorithm consists of four steps. The first step is an image enhancement process composed of low-pass filtering and local contrast enhancement. The second step employs recursive global adaptive thresholding method based on the statistical information of the contrast enhanced image to separate cells and some other image features from the background. Due to the effective image enhancement produced in the previous step, global adaptive thresholding is sufficient to provide satisfactory image thresholding results. The third step in the segmentation process is composed of boundary tracking and morphological measurement for cell detection. A new efficient boundary tracking scheme is proposed. In the last step non-cell objects are found and removed from the segmented image based on the morphological information obtained in the last step.


Reaction between a variety of bis(trimethylsilyl)methyl derivatives and carbonyl compounds under fluoride ion as catalyst is described. The reaction works especially well with nonenolizable carbonyl compounds to give the expected alkenes in high yields and, in some cases, with high stereoselectivity. Application of this methodology to an intramolecular alkenation providing a tricyclic benzocarbacephem ring system is also described


Based on the latest revised seismic isolation codes of major seismic countries (China, the United States and Japan), a comparative analysis of design standards and detailed prescriptions of these countries are given. The result indicates that although the base earthquake-isolated technology has been developed rapidly nowadays, some aspects still need further consideration,the development and application of inter-storey earthquake-isolated technology from structural system, and the influence of P-delta effect and vertical earthquake effect on earthquake-isolated buildings from structures design.


The pre-settlement vegetation of Kalamazoo County has been described by at least five authors since 1900, all of whom base their deductions on the United States Survey Field Notes. Authors generally agree that the KBS area was dominated by oak savanna that was perpetuated by fires regularly set by Native American Indians. The Potawatomi tribe resided in this area at the time of pioneer settlement in the 1830s; to other tribes in the region they were known as the "fire-makers." Their population in Kalamazoo County in the 1830s could have been as high as 1,000.


Direct frequency changers are designed to work under a balanced input condition. The three phase power frequency input voltage of static power converters may be unbalanced either in phase or in amplitude. This paper discusses a novel technique to produce the output of the converter balanced when the input is amplitude unbalanced. The proposed three phase direct frequency changer can find wide applications in motion control, specifically AC drives, when the input AC is amplitude unbalanced. Analytically predicted results are verified by simulation.<<ETX>>


Abstract Introduction Irregular sleep has been associated with worse cardio-metabolic health compared to regular sleep, but prior studies are limited in sample size and have assessed sleep irregularity over short assessment periods (7-14 days). This study investigated associations between sleep irregularity and hypertension in a large, global sample over multiple months. Methods Data from 12,300 participants (Mean ± SD; 50 ± 12 years, 12% females) who used an under-mattress sleep device and a portable blood pressure monitor between July 2020 and March 2021 were included. Each participant had ~180 nights of recordings and ~70 blood pressure entries. Sleep duration regularity was assessed as the standard deviation of device-assessed total sleep time. Sleep timing regularity was assessed as the standard deviation of sleep onset time and sleep midpoint. Logistic regressions were conducted, controlling for age, sex, BMI, and mean total sleep time. Results Across total sleep time quartiles, sleep duration irregularity was consistently associated with a 9-15% increase in hypertension risk. A 38-minute increase in sleep midpoint irregularity was associated with an 11% (1.11 [1.03, 1.20]) increase in hypertension risk, independent of mean total sleep time and mean sleep midpoint. Similarly, a ~31-minute increase in sleep onset time irregularity was associated with a 29% increased risk of hypertension (1.29 [1.18, 1.42]). Conclusions Irregular sleep, regardless of average total sleep time, was associated with increased hypertension risk. Further assessment of day-to-day fluctuations in sleep duration and timing for potential effects on next-day blood pressure and cardiovascular health outcomes is warranted.


This paper presents a framework and an intranet solution for an electronic marker of human competencies to ease the team building process, as well as to support knowledge and competence exchange. This systems should allow to reduce the transaction costs and time requested at the creation stage of a team, and ensure a higher quality of the selection. We examine the difficult issue of competence modeling, present the solutions adopted and propose three market mechanisms for (1) searching and locating the necessary competencies, (2) making calls for bids and (3) negotiating contracts with the pre-selected team members.


Toenail chromium and copper concentrations in toenails of some inhabitants resident in Kano for at least six months were assessed by atomic absorption spectrometry. Average toenail chromium and copper concentrations were 1.33 ± 0.68 and 27.62 ± 13.29 µg/g respectively. Both chromium and copper concentrations in nails decreased with age indicating that these metals may be playing some physiological functions during the formative years. Their concentrations were inversely related to age with approximate average of 10% decline with each decade of age.

 Key words: Chromium, copper, toenails, Kano, Nigeria


We correct a theorem in the literature describing the rank of the span of the images of a point on a modular curve under Hecke correspondences. Let X be a modular curve over Q associated to one of the congruence subgroups Γ0(N), Γ1(N), or Γ(N). Assume that X has genus at least 2. Identify X with its image in the jacobian J under the map taking x to the class of x −∞, where ∞ ∈ X(Q) denotes the usual cusp. Let Jtors denote the torsion subgroup of J(Q). For any prime p not dividing N , the Hecke correspondence Tp on X induces an endomorphism τp of J . Finally, let ZTp(x) denote the Z-span in J(Q) of the p + 1 points of X(Q) obtained by applying Tp to x. The main result of this note is Theorem 2, which contradicts the following. Statement 1 (Theorem 0.4 in [Si2]). Let x ∈ X(Q) be a noncuspidal, non-CM point. Then for p sufficiently large, rank ZTp(x) = { p, if x ∈ Jtors. p + 1, otherwise. It is only the last sentence of the proof in [Si2] that is flawed: the "i(x) ∈ Jtors or τp = 0" on the left hand side of the last chain of equivalences should be replaced by "τp(i(x)) ∈ Jtors". Therefore Statement 1 becomes true if "x ∈ Jtors" is replaced by "τpx ∈ Jtors". Theorem 0.4 in [Si2] plays the role only of a remark: the main results of that paper, which are concerned with the heights of the images of a point under a Hecke correspondence, are unaffected by the correction. Silverman explained to me that he attributed Theorem 0.4 in [Si2] to "Mazur, unpublished" because Mazur sketched a statement and proof to him verbally; therefore he feels that Mazur should get credit for the idea, while he accepts responsibility for the minor error in its write-up. Theorem 2. Suppose that J is isogenous over Q to a product of elliptic curves E×F . Then there exist infinitely many nontorsion, noncuspidal, non-CM points x ∈ X(Q) such that there exist infinitely many primes p not dividing N for which rank ZTp(x) = p. Received October 23, 2001. 2000 Mathematics Subject Classification. Primary 14G35.


In the current volume, the selected studies have been grouped into three thematic sections, presenting readers with a set of distinct but related research on meaningful issues for a modern learning experience. The first three chapters present professional and teacher development perspectives and collectively shed light on how to develop, maintain, and improve pre and in-service teacher training and professional development. The second set of four chapters provide research findings that describe the results of direct applications of modern learning elements through course assignments and teaching approaches. The final five chapters focus on critical thinking and range in their focus from classroom-based studies to full-scale curriculum reform.


If real New Zealanders are Maoris will someone please tell me what I am? One dictionary definition of a Maori is 'native of New Zealand' . . . . Since I was born in New Zealand, and anyone who wishes to call himself a Maori is a Maori, does that mean I am a Maori? I am not a European, by the same token I am not English. Now it seems as if I am not a New Zealander. Am I therefore a Stateless person?


To study the effects of methanol and ethanol foliar application (0, 10 and 20 % v/v) and NaCl salinity stress (0, 75 and 150 mM) on yield and some physiological traits of geranium (Pelargonium graveolens L.), a factorial experiment was conducted based on completely randomized design with three replications. Salinity showed significant effect on all characteristics, except root dry weight, chlorophyll b and Fe content. Effect of foliar application of methanol and ethanol was significant on proline, protein, chlorophyll a, essential oil, Fe and K content, root dry weight and IC50. The results also revealed the significant interaction of salinity by foliar application of alcohol in relation to the chlorophyll a and protein content. The greatest protein and chlorophyll a contents were recorded by the NaCl0 + methanol20% treatment, which was significantly different from the corresponding control. Dry weight of aerial parts, K/Na ratio, essential oil, K, P, Fe and Zn contents were negatively affected by the salinity stress. With increasing salinity stress the amounts of malondialdehyde and H2O2 were elevated. Among alcohol treatments, methanol foliar application was more effective than ethanol. Methanol had better effect on IC50, root dry weight, Fe, K and essential oil content, while ethanol20% increased the proline content significantly as compared to the methanol and control treatments. Overall, the results indicated that foliar application of methanol ameliorated the negative effects of salinity in geranium, when averaged over the salinity levels under study.


The competition index model proposed by Hegyi was used to study the intra-specific and inter-specific competition in an Alsophila spinulosa community based on the data in a survey conducted in Xishui Natural Preserve of China's Guizhou province. The intensity of intra- and inter-specific competition of Alsophila spinulosa was found to decrease with the increase in DBH (diameter at breast height) of the plant. The inter-specific competition intensity at the community level was in the order of Alsophila spinulosa Cunninghamia lanceolata Cornus controversa Polyspora axillaries Beilschmiedia kweichowensis Myrica rubra Cotinus coggygria Betula insignis Ilex micrococca Aleurites fordii, and that at the individual level was in the order of Cotinus coggygria Alniphyllum forthunei Polyspora axillaries Pinus massoniana Cornus controversa Myrica rubra Alsophila spinulosa Rhus chinensis Trachycarous fortunei Eurya japonica Mallotus barbatus. The DBH of the objective trees was negatively correlated with competition intensity. Ecological properties of Cornus controversa, Eurya japonica and Beilschmiedia kweichowensis are close to those of Alsophila spinulosa.


Abstract : Theoretical aspects, production methods, and evaluation techniques of narrow band optical filters, which employ a thin sheet of mica in place of the usual evaporated dielectric spacer layer, are described. Such filters have been made and are reported with half-widths of less than 2 A and with transmission on the order of 60%. In particular, details are given of the method of cleaving the mica sheets and the measurement of absorption. A filter holder is described which makes it possible to construct filters of practical size. Theoretical and experimental values are given for the angular sensitivity. Other properties discussed are the tunability, background, the spectral region for which they can be constructed, and the stability of the filters with time and with temperature changes. Recommendations for future work with such narrow band optical filters are presented and continuation of the program is recommended. (Author)


Previous research has reported substantial levels of nostalgia for the Soviet era among citizens of some of the independent republics that emerged from its collapse. We report new analyses from eight former Soviet republics, and from two surveys, in 2001 and 2010, comparing attitudes to government in the Soviet period and at the time of the surveys, as well as expectations for the future. Everywhere, views of the past have become less positive and those of the present more positive. However, both the views in each survey and the change between each of them vary among countries and socio-demographic groups.


All projects require that the materials necessary for their construction be organized, easily accessible, and safely stored. These requirements become more pronounced when multiple people work on a project simultaneously. CGI animation projects specifically have asset management needs particular to the industry. Yet there has been relatively little attention given to this topic in the literature. This sketch shows how a new asset management tool called ShotTracker2, developed at Mainframe Entertainment Inc, was essential to the efficient completion of the direct-to-video feature Barbie as Rapunzel.


A two-electron model of direct excitation in Li-Na collisions is developed, based upon one-electron eigenstates of the separated atoms. A valence-bond-type two-electron atomic basis, antisymmetrised and modified by the translational phase factors, is used in the expansion of the electronic scattering state. The time-dependent Schrodinger equation is solved by the impact parameter method assuming a rectilinear trajectory and constant relative velocity of the alkali cores. Solutions of the resulting close-coupled equations have been obtained in the high-energy limit which defines a model with complete neglect of exchange contributions. Various sets of basis functions, Li(2s/2p)Na(3s/3p), involving single and/or double (simultaneous) excitation of the alkali atoms have been used. The aim was to obtain first estimates of Li(2p) and Na(3p) excitation cross sections and polarisations as functions of collision energy and to probe the details of the direct-excitation mechanism. The single-excitation predictions match recent experimental cross sections at 50-60 keV centre-of-mass energy. The double-excitation contributions are significant but the present calculations tend to overemphasize their importance. Excitation out of the collision plane, an allowed two-electron excitation process, is important at centre-of-mass energies above 100 keV.


We develop an analytically solvable version of the central model of 'new economic geography', the so called core-periphery model by Krugman. While the modified model reproduces all the appealing features of the original one, it also allows us to obtain additional analytical results that are out of reach in Krugman's set-up. First, we are able to assess the exact number of equilibria and their global stability properties. Second, we are able to investigate the implications of exogenous asymmetries between countries. This is achieved by introducing heterogeneity between high-skill mobile and low-skill immobile workers, which may also be an empirically attractive property. Copyright 2003, Oxford University Press.


This paper examines codend size selectivity in the Chilean hake (Merluccius gayi gayi) industrial fishery by means of four mesh sizes opening in the codend (100, 110, 130 and 140 mm mesh openings) and using the cover codend method. The data was analyzed by haul, using the SELECT model with both the Logistic and Richards selection curves. For each mesh size opening and sex the combined haul analysis was made with the Fryer model, and with these results we determine the Master Curves, by sex. Based on critical length and maturity length at 50% estimated for this specie we determined the optimum mesh size opening for the trawl fishery. The rate of escape of cmomon hake increased exponentially with the size of mesh opening. The Logistic selection model was chosen based on the likelihood ratio test for all hauls analyzed. From the mean selection curves (incorporating haul variation) fitted to data for combined sexes, the total length of 50% retention (l 50 ) were estimated to be 39.3, 39.7, 41.1 and 43.6 cm of total length for 100, 110, 130 and 140 mm of mesh size opening. The values of l 50 for females were higher than those for males. We recommended 120 mm of mesh size opening in the codend in order to protect the spawning fraction of Chilean hake stock and maximize the biomass of the cohorts.


In this work we consider the modeling and the design of control allocation algorithms for an innovative prototype of ducted-fan aerial robot characterized by a redundant number of aerodynamic control surfaces. The control allocation algorithms are designed to combine the effects of the aerodynamic forces produced by deflecting the control surfaces in order to generate a desired resultant control wrench vector. It is shown how, employing also the aerodynamic drag forces, additional control inputs can be generated to improve the number of degrees of freedom that can be actually governed by the control law. The proposed solutions are then compared both in term of energy efficiency and control properties by taking advantage of a detailed model of the system.


The two most frequently quantified metrics of net energy analysis–the energy return on (energy) investment and the energy payback period–do not capture the growth rate potential of an energy supply infrastructure. This is because the analysis underlying these metrics is essentially static–all energy inputs and outputs are treated the same, regardless of where they occur in the life cycle of the infrastructure. We develop a dynamic energy analysis framework to model the growth potential of alternative electricity supply infrastructures. An additional figure of merit, the infrastructure doubling time, is introduced. This metric highlights the critical importance of the time phasing of the initial energy investment for emplacing a given infrastructure, as opposed to the ongoing O&M energy expenditures, for the infrastructure's growth potential. The doubling time metric also captures the influence of capacity factor, licensing and construction time lags.


The invention discloses production of nickel aminosulfonate or cobalt aminosulfonate through an ion exchange method; the production of nickel aminosulfonate or cobalt aminosulfonate through the ion exchange method relates to ion exchange resin, an ion exchange column, amino sulfonic acid, a pure alkali solution and deionized water. The production comprises the production steps of ion exchange resin transformation, adsorption, elution and the like. The implementation scheme having the advantages of simple process route, low cost and continuous production is provided for production of nickel aminosulfonate or cobalt aminosulfonate.


In the Postscript to his introductory volume on international law, Vaughan Lowe takes note of the "tendency at present for international lawyers to write of the growth of [nongovernmental organizations] and other non-State actors, and of the decline of the nation-State, with the gleeful enthusiasm of a cartoon character sawing off the tree branch on which he is sitting."1 Few international lawyers have been so bold as to suggest that domestic juridical persons have reached the threshold ofa measure of international legal personality even when such companies have extensive international links but fall short of being "transnational." In their doctrinal writings Russian international lawyers certainly did not anticipate2 the remarkable step taken by the Russian Federation of endowing an individual state corporation with various powers in treaty making, including the right to conclude treaties with foreign states or their departments. The state corporation concerned is the State Atomic Energy Corporation "Rosatom," established on the basis of a federal law of December 1, 2007.3 The state corporation as a legal mechanism was recently introduced into Russian law and finds no exact predecessor in either prerevolutionary Russian or Soviet law.4 Nor is it singled out in the types of juridical person recognized by the Civil Code of the Russian Federation. The origins of the state corporation lie in an amendment of July 8, 1999, to the Federal Law on Noncommercial Organizations of


simple, highly reactive toxic molecule and an environmental pollutant in cigarette smoke and smog. In 1987 Palmer et al1 discovered NO to be EDRF. The relevance of NO opened up a new era of biologic research. In 1992 the American Association for the Advancement of Science voted NO as the Molecule of the Year.2 NO has become the focus of intense clinical and basic science research as an important mediator of inflammation and vasomotor tone. NO is a potent pulmonary vasodilator, and its use as an inhalational agent has been proposed in a number of cardiopulmonary disease states. Because inhaled NO reliably produces clinically significant increases in arterial oxygenation (PaO2) in animals and human patients with ARDS, its potential to alter clinical outcome in ARDS was approached with great enthusiasm. CHEMISTRY AND PHARMACOLOGY In 1980, intact endothelium was demonstrated to be crucial for acetylcholine-induced vasodilation of isolated strips of arteries.3 EDRF is the substance released on stimulation of the endothelial cells. NO is now known to account for the biologic activity of EDRF. Nitric oxide is a simple, unstable, gaseous free radical that is freely diffusible across cell membranes.4,5 Because of its rapid conversion to nitrates by oxygen, its half-life has been approximated from 3 to 50 seconds.5,6 In the vascular endothelial cell, NO is synthesized from the terminal guanidine nitrogen of L-arginine by the enzyme NO synthase. Molecular oxygen is incorporated into the terminal nitrogen group, forming NO and citrulline.7 NO diffuses rapidly into subjacent vascular smooth muscle, where it binds to the heme iron complex of soluble guanylate cyclase. The resulting nitrosyl-heme activates guanylate cyclase, stimulating the production of cGMP. cGMP produces relaxation of vascular smooth muscle by decreasing intracellular calcium. Additionally, NO directly stimulates calciumdependent K channels, causing hyperpolarization and vascular smooth muscle cell relaxation via a cGMPindependent mechanism.8 One of the unique properties of NO is that once it diffuses into the intravascular space, it is rapidly inactivated by binding avidly to hemoglobin. In fact, the combination of NO with reduced hemoglobin is the fastest direct action so far measured of an oxygenInhalation of nitric oxide in acute respiratory distress syndrome


Tell your guests when it's time to go: When avidin caps are attached to biotinylated colloidal mesoporous silica, the four subunits of the protein avidin can each bind to a biotin moiety attached to the surface (see picture). The resulting material is a promising candidate for the design of smart detergents or drug-delivery systems. The caps can be opened to release guest molecules by controlled enzymatic hydrolysis of the protein.


E-commerce and the industrial revolution have impacted the warehousing system. The warehousing system is continuously developing into modern warehousing. One of the features of a modern warehousing system is a forklift that can operate independently or automatically. Autonomous forklifts have a broad scope. This study presents the roll stability control of autonomous forklifts. The roll stability control is necessary to avoid instability that can cause rollover. The center of gravity is one of the crucial factors in anticipating rollover. The center of gravity can be affected by the weight of the load and the speed at which the forklift operates. The forklift dynamic model is developed here by considering the calculated center of gravity and the lateral transfer ratio (LTR). A linear quadratic regulator (LQR) and model predictive control (MPC) are then employed to stabilize and regulate the LTR at zero. The simulation results of a case study show that LQR and MPC may avoid rollover with a relatively fast response when the forklift has half loads and slow movements.


The of is to the findings of a prospective clinical trial in which eyes with extensive neovascular proliferative diabetic retinopathy received argon laser PRP distributed to the midperipheral fundus and either the more central fundus, or the more peripheral fundus with the type of distribution being randomly determined.


Ethnopharmacological relevance: Platycerium bifurcatum (CAV.) C. Chr., Commonly known as staghorn fern is an epiphytic plant with diverse medicinal uses, such as anti-ulcer remedy, treating oedema, coughs and hypertension. This research was aim at evaluating the pharmacognostic profile of P. Bifurcatum. Methods: The fresh and air-dried plant materials were evaluated for microscopic characters, ash values, extractive values, moisture content and phytoconstituents. Results: Pharmacognostic evaluation revealed two shape of leaves, one round and the other forked-like shape, dark and light green colour, slightly coarse texture at the abaxial surface and hairy due to the trichome at the adaxial surface, reticulate leaf venation and margin entire, presence non- grandular stellate trichomes at the lower epidermal layer, spongy mesopghyll, collenchyma cells, vascular bundles straight type of epidermal cell wall, anisocytes stomata. Moisture content of 6.283%, total ash value of 8.25% within the standard range, acid insoluble ash of 1%, water soluble of 6.0% and phytochemical screening analysis shows the presence of phenolic, saponins, glycosides and triterpenoid constituents. Conclusion: this study reports the first time the pharmacognostic properties of P. bifurcatum.


We introduce a new cost function for the training of a neural network classifier in conditions of high class imbalance. This function, based on an approximate confusion matrix, represents a balance of sensitivity and specificity and is thus well suited to problems where cost functions such as the mean squared error and cross entropy are prone to overpredicting the majority class. The benefit of the new measure is shown on a set of common class-imbalanced datasets using the Matthews Correlation Coefficient as an independent scoring measure.


Guy Beiner's edited volume Pandemic Re-Awakenings is a comprehensive treatment of the theme of "memory" in the history and historiography of the 1918-1920 influenza pandemic. Bringing together twenty-three authors researching various aspects of the flu, Beiner's volume examines processes of remembering, forgetting and rediscovering that have determined individual and collective memories of the flu, their absence, continuity and reemergence after the flu's centenary and COVID-19. The result is a thorough and nuanced collection of chapters that express the complexities of memory in different parts of the world and from different perspectives. Beiner's volume is not the first to discuss memory and the flu, nor is the topic new ground for Beiner and contributors like Howard Philips and David Killingray. Pandemic Re-Awakenings marks the first time these authors share a single volume and the second time since 2003 that Phillips and Killingray share the same volume with other specialists in the history of disease, such as Geoffrey Rice and Nancy Bristow.


The building right can be given on land with ownership rights and the granting of rights to build on land with ownership rights is made with the deed of the official land deed maker (hereinafter referred to as the PPAT Deed) instead of the deed made before a Notary (hereinafter referred to as the Notary Deed), where the Deed The PPAT will be registered at the land office. A notary in the view of society is considered an official, a place for someone to obtain reliable legal advice, a place for making strong legal documents in a legal process that will be carried out, especially in making a deed of agreement for hotel development. This study aims to determine the authority of the notary in making a notarial deed of land use rights on land for hotel development, second, how is the existence of a notarial deed in granting building use rights over land of ownership for hotel construction. The type of this research is normative legal research, data sources based on primary legal materials, secondary legal materials and tertiary legal materials. The approach used in this research is a statutory approach. The technique of collecting legal data is literature study. The results in the research are the task of the notary office is to formulate the wishes or actions of the parties into an authentic deed, so that to carry out its duties a notary must adhere to the applicable regulations, secondly the existence of a notary deed in granting development rights over land of ownership rights for hotel development, the existence of a notary deed in granting the right to build on land owned for hotel construction has a positive character because there are very important requirements, namely an evidence of ownership of land, as well as the building on it in a formal or written form of a certificate


Here we report a Vertical Hybrid Field Effect Transistor (VHFET) that shows an improved saturated output characteristics. Up till today the injection limited regime in vertical transistor was realized using an injection barrier as well as a buried semiconductor (SC) under the source contact. Using previous reported simulations and a new fabrication technique we successfully fabricated and characterized a functional device which operates at the injection limited regime without the need of a current limited source injection barrier. The new architecture shows better gate control with 5 ∙ 105 on/off ratio and 240 mV/dec subthreshold swing. Furthermore, we can set design rules for the vertical source contact to enable high performance Vertical Field Effect Transistors (VFET), some of which are applicable to any short-channel transistor.


This present work study on water quality and benthic Macro invertebrate in Gorganrood, river. The research was carried out at 6 sampling site and the abundance and diversity of benthos were monitored along the length of river between 2007_2008_14 families were recorded in phyla, namely Annelidae, Mollusca,....
The greatest number of species was at 1 st station and the least number was at 6th station. The upper section supported more diverse community then the lower section.
A low macro invertebrate abundance was observed during spring as a result of heavy rainfall and flood, and generally in all lowest section because of high valve of nitrogen and other nutrients.
Water physiochemical parameters such as Phosphate, Nitrate,TPS and others were measured and water quality were studied through different indices such as saprobic system, Helsinhoff (FBI), BMWP and the results were compared and evaluated by physical chemical and parameters. The result indicated that the water quality in the up stream and the middle were good to fair, but the down stream qualities were pour at all sites.


The portfolio of the automotive market appears more and more low-emission and zero-emission propulsions in vehicles. This is the result of measures taken to limit or even eliminate the emission of harmful substances into the atmosphere generated by vehicles. The article covers issues related to energy conversion in automotive drive systems currently offered by automotive manufacturers. Standard, hybrid, hybrid plug-in, electric and fuel cells drive system were analyzed. Attention was drawn to the chain of energy transformations related to each of the analyzed drive systems. The efficiency of the presented vehicle drive systems was analyzed. General conclusions were formulated regarding the method of analyzing energy changes related to the operation of automotive propulsion systems. The article reviews selected author's own works on hybrid and hydrogen propulsions.


A study of the sensitivity for the inclusive production of Standard Model Higgs bosons ${;\rm H};$ decaying in ZZ$^{;(*)};$ pairs is presented with the CMS experiment at the CERN LHC $pp$ collider at 14 TeV centre of mass energy, for the integrated luminosity of 1 fb$^{;-1};$. The analysis is performed for the leptonic decay channels ${;\rm H}; \rightarrow {;\rm Z};{;\rm Z};^{;(*)}; \rightarrow 4\ell$ with $\ell = e, \mu$ and for a mass $m_{;\rm H};$ in the range from $120$ to $250 \GeVcc$. Signal and background datasets obtained with a detailed Monte Carlo simulation of the detector response, including the limited inter-calibration and alignment precision expected at startup luminosities, are treated using a complete reconstruction chain. A simple $m_{;\rm H};$ independent sequence of cuts is established which provides a clean sample of $4\ell$ events while preserving the highest signal detection efficiency. A signal with a significance above 2 standard deviations is found unlikely for a Higgs boson with a mass $m_{;\rm H};$ lying anywhere in the mass range considered. In absence of significant deviations from background expectations, upper limits on the production cross-section of a Standard Model-like Higgs boson can be established. The limits extend beyond existing constraints.


A constructive criterion for decoupling the steady states of linear multivariable systems is developed. The criterion consists of n(n-1) inequalities with the type numbers of the compensator transfer functions as the unknowns. These unknowns can be chosen to satisfy the inequalities and hence achieve a steady state decoupling scheme. It turns out that pure integrators in the loops play an important role. An extended root locus design method is then developed to take care of the stability and transient response. The overall procedure is applied to the compensation design for STOL C-8A aircraft in the approach mode.


This paper describes how cold mixes, more precisely those made with emulsion, have several specific features (presence of water, aggregate-emulsion, reactivity, properties evolving with time). Their behavior in many respects is different from that of hot mixes. Diverse types of cold mix have now reached a considerable level of development: grave-emulsion, open-graded cold mix asphalt concrete, stockpile mixtures. Others, like dense cold mix asphalt concrete, have not been extensively developed yet; some are still at research stage. The various types of cold mix are described. Until recently, there was only a small number of design methods for cold mix, which are almost totally empirical. The tests comprised in these methods are mainly derived from tests for hot mixes. It is therefore not surprising that the specifications applicable to cold mixes are still limited and, sometimes, not fully adequate. An important research has been conducted recently. It has produced a specific design method for cold mixes. The main steps of this method are presented: coating quality, early cohesion, compactability, accelerated curing, water sensitivity, rutting resistance and stiffness modulus. The tests have been selected in order to support performance - based specifications. On the other hand, several site sections cold mix pavement and/or wearing courses have been monitored. The output of the long term monitoring has been compared to the results of laboratory evaluation. This exercise results in a more precise definition of the field of application for each type of cold mix, in terms of position in the pavement, thickness, allowable traffic, etc. Globally, the knowledge of cold mix properties has been improved. The cold mix behavior modeling has progressed and more adequate pavement design can be performed.


The data streaming method is provided through the peer network, the peer server that contains the agent and client agents-to. The method comprising: in response to requests from a client agent for a particular file, assigning a server agent sets a, sub-stream set, each of which is to split in frames configured with the size of the particular file, based on the specified file to configure and, wherein the sub-stream set is transmitted a plurality of active server agent contains, and in addition to the network characteristics according to the minimum number of excess include a number of duplicated active server agent selected packet (packets) to the client agent and that; The sub-stream by managing the set asynchronously each server agent streams are configured to set the frame in said sub-stream set independently of the other server agents; Substreams per set rate-based congestion control will be adopted such that the bit rate associated with said sub-stream set maintained above a certain threshold.


This study offers treatment of all the major doctrines, personalities and defining features of the Spanish fascist movement, from its beginnings until the death of General Francisco Franco in 1977. The author describes and analyzes the development of the Falangist party both prior to and during the Spanish Civil War, presenting a detailed analysis of its transformation into the state party of the Franco regime - Falange Espanola Tradicionalista - as well as its ultimate conversion into the psuedofascist Movimiento Nacional. Particular attention is devoted to the crucial years 1939-1942, when the Falangists endeavoured to expand their influence and convert the Franco regime into a fully Fascist system.


Dirichlet`s task is solved for unstable of hot liquid stream moving into radial-divergency canal. Solution was fined by consistent application laplace's conformation and furie`s sinus-conformation. Is written equation heatchange for moving of liquid in cylindrical coordinates. Is taken in consideration the canal simmetration for coordinate . Heatexchange only by convection in direction of radial coordinate and by heatconduction along axal is taken in consideration. In process of solution was find time's parameter, value of which separate unstationary and stationary conditions of heatconduction. In result solutions for calculation unstable and stationary temperature field and correlated with them local heat streams on the walls of canal was obtained. The stationary solution is full identifical by solution which were obtained in [5] for stationary of heatchange into radial-divergency canal.


A general analysis of a coaxial-line/radial-line region junction is presented for the case in which the center conductor is sheathed in a dielectric and extends the full width between two parallel metal plates. Expressions for the current distribution and the admittance of the junction are presented. Two example environments are considered, a rectangular waveguide and a base entrant cylindrical cavity, although the technique can be used for other environments. Comparison of theoretical and experimental results for these two cases shows the theory to be very accurate. >


Patition-based reasoning(PBR) is a method of reasoning with partitions of related logical axioms.A new method of web service composition based on MP algorithm is proposed for improving the composition of web services that is located in different UDDIs,and the performance of the semantic reasoner in the process of web service composition. Thus the new method proves more efficient than the one based on traditional theorem proving.A method of extracting the process model from proof based on the idea ofπ-calculus is also introduced.To make use of the subtype relation provided by semantic reasoner,a new process to handle this process is defined systematically.


The problems of increasing the value of scientific classifiers for the systematization of scientific information in the digital age are discussed, for example, the classification of documents (assignment of indices-classifiers) is a traditional way of systematization of knowledge and information search. In this paper we propose a recommendation system for automated selection of Universal decimal classification (UDC) indices for physical and mathematical documents. This system implements one of the services of the digital mathematical library Lobachevskii-DML. The proposed algorithm is based on the use of terms extracted from the title, the list of keywords and annotations given in the analyzed documents. Extraction of terms from the documents of the collection is carried out with the help of software tools developed by us, taking into account the stylistic features of the documents and the positions in the text of the required terms. The data obtained were included in a dictionary that has an inverted index structure. The generated dictionary contains both classification features and sets of key terms, which are used to systematize and classify the material. Most of these terms were obtained by automated processing of the collection of archives of physical and mathematical publications of the AllRussian mathematical portal Math-Net.Ru. The proposed variant of the semantic markup of a table of indices of the Universal decimal classification. The model of classification of scientific documents is described.


It is the purpose of this study to consider the Anglo-American child--to examine his achievement in a situation where much consideration will of necessity be given to the instructional needs peculiar to the predominating group.


Subrotational cooling of the AlH+ ion to the miliKelvin regime, using optimally shaped pulses, is computed. The coherent electromagnetic fields induce purity-conserved transformations and do not change the sample temperature. A decrease in a sample temperature, manifested by an increase of purity, is achieved by the complementary uncontrolled spontaneous emission which changes the entropy of the system. We employ optimal control theory to find a pulse that stirs the system into a population configuration that will result in cooling, upon multicycle excitation-emission steps. The obtained optimal transformation was shown capable to cool molecular ions to the subkelvins regime.


There are three major conceptualizations of Intellectual Disability (ID): as a lower end of the Gaussian distribution of intelligence in the population, a bio-medical condition secondary to adverse influences on the developing brain (neurodevelopmental disorder), and as a socio-cultural construct focusing on impairments in adaptive functioning and the need for extra supports. Modern definitions incorporate all these aspects. There are hundreds of causes of ID, both genetic and environmental, that act either singly or in combination. These are classified based on the timing (pre-, peri-, and postnatal) and the type of cause. Genetic factors include chromosomal disorders, microdeletions, single gene disorders and newly discovered mechanisms such as copy number variations. Environmental factors may operate in prenatal, perinatal, or postnatal periods of development. Pathophysiological pathways leading to ID involve disruption of neurodevelopment and neuronal functioning, such as neural proliferation, migration, connectivity, synaptic development, intra- and inter-cellular signalling pathways, and metabolism. Identifying the aetiology has major clinical implications.


Subgrade is an important part in road pavement construction, which serves as the foundation and must have the ability to bear the traffic load applying on the surface of the pavement. This study examined changes in the carrying capacity of soft soil after stabilization process using asphalt emulsion. The results of this study indicate that the stabilization process using asphalt emulsion can lower the Plasticity Index and increase the dry density and strength of the soil.


Recently A.R.Chouikha gave a new characterization of isochronicity of center at the origin for the equation $x"+g(x)=0$, where $g$ is a real smooth function defined in some neighborhood of $0 \in \R$. We describe another proof of his characterization and some new development of the subject.


There is an increasing body of evidence to suggest that cel lular immunity may be an important factor in host resistance to tumors (20, 21, 24). Investigation of this question has been slowed by the lack of a reproducible in vitro assay for cellular sensitivity to tumor antigens. This paper will review an in vitro method which has proven to be useful in the study of cellular sensitivity as it is related to delayed hypersensitivity to bacterial and other protein antigens, to autoimmunity, and to homograft reactions; it is hoped that this system may be adaptable to the study of tumor immunity. The in vitro technic used in these studies is based on a method described by George and Vaughan (17). Peritoneal obtained from pigs exhibiting delayed hypersensitivity are placed in capillary tubes; the of of the tubes glass in is when The is described in detail elsewhere (10).


Fibrous ceria has been synthesized by a chemical co-precipitation/ripening method. It was found that these catalysts are highly efficient in soot combustion activity under tight and close contact conditions. In comparison, the peak temperature of the soot combustion under tight and loose contact conditions was shifted from 397 °C to 445 °C


The present invention relates to a reduction method of lipid of propolis, specifically wax. The present invention reduces lipid by precipitating a fat-soluble ingredient through polymerization by treating propolis solvent extract with lipase. Moreover, the lipid reduction method of the present invention can maintain antioxidant activity and antimicrobial activity of propolis after a lipid reduction process. [Reference numerals] (AA) Palmitic acid (g/100g of raw material);(BB,EE) Control group;(CC,FF) Example;(DD) Length fatty acids (g/100g of raw material)


A low complexity DC-compensated weighted two-bit transform (2BT) based multiple candidate motion estimation algorithm is proposed in this paper. By exploiting almost the identical operations in two different matching error criteria and incorporating the DC-term into them, we can efficiently determine two best motion vectors according to the respective matching criteria and can enhance the overall motion estimation accuracy. Experimental results show that the proposed algorithm achieves peak-to-peak signal-to-noise ratio (PSNR) gains about 0.83dB on average compared with the conventional 2BT-based motion estimation with negligible complexity increase.


Summary

1
The importance of two features of the predator functional response (satiation and predator dependence) is investigated in the wolf–moose interaction on Isle Royale National Park (Michigan, USA). This is done by fitting and comparing nine different functional response models to the observed kill rates.

2
Three different observational scales (the whole island, the wolf packs, or a 'mixed' scale) are used to assess the sensitivity of the detected properties with respect to these spatial scales.

3
Independently of the observational scale and of statistical assumptions on data structure, strong predator dependence and satiation of the wolf functional response are found. The 'mixed' scale gives the most consistent results, suggesting that predation should be measured for each pack, but that packs share all moose on the island. On this scale, the functional response is clearly ratio-dependent.


We show that for C*‐algebras A and B, there is a natural open bijection from Glimm (A) × Glimm (B) to Glimm (A ⊗α B) (where A ⊗α B denotes the minimal C*‐tensor product), and identify a large class of C*‐algebras A for which the map is continuous for arbitrary B. As a consequence, we determine the structure space of the centre of the multiplier algebra ZM(A ⊗α B) in terms of Glimm (A) and Glimm (B), and give necessary and sufficient conditions for the inclusion ZM(A) ⊗ ZM(B) ⊆ ZM(A ⊗α B) to be surjective. Further we show that when the Glimm spaces are considered as sets of ideals, the map (G, H) ↦ G ⊗α B+A ⊗α H implements the above bijection, extending a result of Kaniuth by eliminating the assumption of property (F).


Objective:To investigate the clinical efficacy of treatingneonatal jaundice children with Yinchen Lizhong Decoction,and explore the effect of serum bilirubin and jaundice subsided state. Methods:82 neonatal jaundice children were randomly divided into a control group of 41 cases and anobservation group of 41 cases from April 2013 to November 2014.Patients in the control group were treated with phenobarbital tablets and blue light;while patients in the observation group were treated with Yinchen Lizhong Decoction for oral and fumigation,1 agent/day,7 days for treatment. We observed the improvement state of symptoms,and evaluated the clinical curative effect;we tested the level of serum bilirubinpretherapy and post-treatment,and recorded the time of bilirubin drop to normal,jaundice recession and hospital stays. Results:After treatment,the main clinical symptoms of the patients in two groups,such as facial skin yellow,dark yellow,abdominal distension,loose stool and lack of burnout,were improved clearly compared with before treatment,the degree of change in the observation group was more pronounced,the efficiency for patients in the observation group is 90.2%,which was higher than that of the controlgroup 70.7%,the difference is significant(P0.05);the level of serum bilirubin went down clearly,the degree of change in the observation group was more pronounced,the difference is significant(P0.05);the time of bilirubin drop to normal,jaundice recession and hospital staysfor patients in the observation group was shorter than that of the controlgroup,the difference is significant(P0.05). Conclusion:The self-made decoction is form yinchen lizhong decoction and good at warming the spleen and dissipating dampness,which is closely matched with thepathogenesis characteristics of cold-dampness disturbing spleen. The therapy can improve the clinical symptoms. Meanwhile,it is good at lowing the level of serum bilirubin and jaundice recession,can effectively shorten the duration of symptoms,which has curative effect,can high light the advantages and characteristics of treating pediatric disease with traditional Chinese medicine,is worthy of further research and development.


The Design Minds The Big Picture Toolkit was one of six K7-12 secondary school design toolkits commissioned by the State Library of Queensland (SLQ) Asia Pacific Design Library (APDL), to facilitate the delivery of the Stage 1 launch of its Design Minds online platform (www.designminds.org.au) partnership initiative with Queensland Government Arts Queensland and the Smithsonian Cooper-Hewitt National Design Museum, on June 29, 2012. Design Minds toolkits are practical guides, underpinned by a combination of one to three of the Design Minds model phases of 'Inquire', 'Ideate' and 'Implement' (supported by at each stage with structured reflection), to enhance existing school curriculum and empower students with real life design exercises, within the classroom environment. Toolkits directly identify links to Naplan, National Curriculum, C2C and Professional Standards benchmarks, as well as the student capabilities of successful and creative 21st century citizens they seek to engender through design thinking. Inspired by the Unlimited: Designing for the Asia Pacific Generation Workshop 2010 (http://eprints.qut.edu.au/47762/), this toolkit explores, through three distinct exercises, 'design for the other 90%', addressing tools and approaches to diverse and changing social, cultural, technological and environmental challenges.

The Design Minds The Big Picture Toolkit challenges students to be active agents for change and to think creatively and optimistically about solutions to future global issues that deliver social, economic and environmental benefits. More generally, it aims to facilitate awareness in young people, of the role of design in society and the value of design thinking skills in generating strategies to solve basic to complex systemic challenges, as well as to inspire post-secondary pathways and idea generation for education. The toolkit encourages students and teachers to develop sketching, making, communication, presentation and collaboration skills to improve their design process, as well as explore further inquiry (background research) to enhance the ideation exercises.
Exercise 1 focuses on the 'Inquire' phase, Exercise 2 the 'Inquire' and 'Ideate' phases, and Exercise 3 concentrates on the 'Implement' phase. Depending on the intensity of the focus, the unit of work could be developed over a 4-5 week program (approximately 4-6 x 60 minute lessons/workshops) or as smaller workshops treated as discrete learning experiences. The toolkit is available for public download from http://designminds.org.au/the-big-picture/ on the Design Minds website.


Abstract Aims The purpose of this study was to evaluate of a 5-week nurse-led educational programme on foot care self-efficacy in high-risk diabetic patients with current foot ulcers. Methods A pilot randomised controlled study was conducted in five acute care hospitals in Switzerland. Nineteen subjects (16 males and 3 females, aged 44–84 years) were randomly assigned to receive foot care education or standard care. Included were patients with diabetes, aged 18 years or older and in treatment for ulceration and/or amputation of the lower limp. The primary outcome measure was the development of foot care self-efficacy determined by the Foot Care Confidence Scale questionnaire (FCCS). The outcome was assessed 5 weeks after randomisation and education. Results The results demonstrated that an evidence-based education programme for high-risk patients can promote short-time foot care-related self-efficacy. While the group comparison showed no significant difference between the groups before and after the intervention, there was a significant difference in self-efficacy comparing the change of the FCCS from baseline to Week 5. Self-efficacy in the intervention group (IG) (M = 9.5, SD ±7.6) was significantly enhanced compared to the control group (CG) (M = 0.64, SD ±8.4, t(17) = 2.4, p = 0.031, r = 0.5). The FCCS score in the IG was significantly higher after the intervention (T = 0, p = 0.02, r = 0.5) compared to the CG after 5 weeks (T = 26.5, p = 0.92, r = 0.02). Conclusions This pilot study demonstrated that nurses successfully accomplish interventions to enhance foot care-related self-efficacy. It is therefore necessary that nurses continue taking such important supporting roles. A larger study, however, is needed to confirm this preliminary data.