1. The enquiry has been conducted in the Radiological Department at St. Mary's Hospital, London. Twenty cases of intrathoracic lymphogranuloma, and six cases of intrathoracic lymphosarcoma are analysed. The importance of radiological examination of the chest as a routine investigation in the lymphomas is stressed. 2. Radiological descriptions of the various appearances are given, and certain uncommon features, e.g., œsophageal involvement, lobar collapse and phrenic paralysis, are discussed. 3. A brief commentary on radiotherapeutic considerations is given. 4. Six selected case reports are given in detail, with appropriate illustrations.


This thesis mainly explicates to use spare pa rts patching mathods to achieve generation of assembly drawings and solve markin g algorithm,which make use of spare parts subprogramme and layer function of sof twares.


Background Acute pancreatitis is an emerging problem in paediatrics. Although the cause is unclear, it may be explained by a heightened awareness of AP in children. Although magnetic resonance cholangiopancreatography (MRCP) is seldom required for the first attack of AP, it constitutes a valuable tool in the evaluation of pancreaticobiliary abnormalities. Congenital anomalies and normal variants of the pancreatic duct are often detected as incidental findings in asymptomatic patients. Occasionally it produces symptoms in childhood and here is a patient presented to us with recurrent episodes of abdominal pain and MRCP helped us in diagnosing the condition and directed us for therapy. Methods 13-year-old male presented to us with complaints of upper abdominal pain since 5 days, vomitings since 4 days. His abdominal pain is radiating to back. He had similar episodes for three times in the past 2 years but were treated conservatively at a local hospital and not been investigated. On examination, vitals were stable and abdominal examination was normal. In view of the history of recurrent acute pancreatitis, MRCP was done. It showed bifid duct of wirsung with duct of santorini opening into its anterior division with bulky body and tail of the pancreas. The patient was conservatively treated, and he recovered well Results It was a case report showing pancreatic duct anomaly causing recurrent acute pancreatitis. Conclusions Congenital variants of the biliopancreatic ductal system provide interesting challenges when discovered during the diagnostic workup of idiopathic acute recurrent pancreatitis. However, most of these variants are clinically irrelevant. Methods for the selection of patients most likely to benefit from invasive therapy need to be refined.


We performed self-consistent multiple-scattering Xα cluster calculations on the electronic structure of self-interstitial impurities (Ga and As) and 3d transition-metal (TM) atoms at three different interstitial sites in GaAs. Our results show that Ga at interstitial sites induces a t2 state resonant in the conduction band, occupied by one electron, and it is electrically inactive. Contrarily, As at interstitial sites may introduce three donor levels in the gap. For the TM impurities we also include many-electron effects. Our results show that the TMs act mostly as donors. We provide important information about stable charge states as a function of chemical potential and the possibility of an enhanced migration barrier via carrier capture.


The idiopathic hypereosinophilic syndrome (HES) comprises a heterogeneous group of disorders with unknown pathogenesis characterized by persistent peripheral blood and bone marrow eosinophilia. And the eosinophil infiltrates of multiple organs in HES lead to severe organ dysfunction. The disseminated intravascular coagulation (DIC) is a rare complication of HES. We have experienced a case of HES complicated with DIC and pulmonary thromboembolism. After intravenous injection of methylprednisone, blood eosinophil count was normalized but DIC was persisted. With cortico steroid and cyclosporine therapy, the disease activity was favorably remitted. (Tuberc Respir Dis 2004; 57:573-578)


Signal to noise ratio(SNR)is an important characteristic of active laser detection system.The signal-noise ratio model of APD is established by analyzing the noise sources of APD and the reflected power of "cat eye" target with focal shift.The influence factors such as focal shift,detection distance and laser divergence angle to the SNR are analyzed.Then the effects are simulated through numerical computation.The results demonstrate that the reflected power of a "cat eye" target will attenuate as the focal shift increases which consequently result in the decrease of SNR.The SNR of APD will also decrease with the increasing of the distance of "cat eye" target and laser divergent angle.The study will lay the foundation for the design and performance evaluation of active laser detection systems based on APD.


Identifying appropriate candidates for hepatitis C therapy can be quite challenging. The decision to initiate treatment depends on disease severity, probability of treatment response, and patient motivation and ability to tolerate treatment. Studies identifying factors associated with treatment decisions must be interpreted with great care because of the many nuances involved. The accompanying article by Hare et al. (pp. 71–76) succeeds in raising some interesting questions about how physicians identify treatment candidates. The investigators found that some hepatitis C patients, such as those coinfected with HIV and those with Medicaid insurance, may be undertreated. However, caution must be used in interpreting these results. Hare's group surveyed 200 American physicians who evaluated 998 hepatitis C patients. Physicians provided data on patients who either did or did not then receive therapy. An auditing process ensured reporting accuracy. Demographic, clinical, and laboratory characteristics were compared between those selected for treatment and thosewhowere not. Investigators sought out reports of treated patients. Therefore, the 75% rate of treatment initiation does not represent the percentage of patients generally offered treatment in clinical practice. Because only a fraction of hepatitis C patients develops clinically significant disease, careful patient selection prioritizes treatment of those with progressive disease. Chronic hepatitis C ismost commonly not symptomatic and not progressive. After 20 years of infection, fewer than 20% of patients develop cirrhosis. After excluding cohorts from tertiary care centers, the rate of progression to cirrhosis is as low as 7%. Even if cirrhosis develops, the large majority of patients will continue to be asymptomatic over many years. Only the minority of cirrhotic patients develops complications of end-stage liver disease, including ascites, variceal bleeding, hepatocellular carcinoma, and hepatic encephalopathy. Shiffman estimated that of 4 million Americans exposed to hepatitis C, only 4% develop symptomatic, end-stage liver disease. Because hepatitis C is so prevalent, this small percentage represents enough patients to make hepatitis C the most common etiology for liver transplantation. Liver biopsy is currently the best predictor of progressive disease. Generally, patients with at least portal fibrosis with some septae and/or moderate inflammation should be considered for hepatitis C treatment. Retrospective studies indicate that most patients with these pathologic features will develop cirrhosis within 10–20 years. The degree of hepatic steatosis is also emerging as a major risk factor for disease progression. A growing body of literature points to the accuracy of non-invasive serologic panels (e.g., Fibrotest andActitest) and transient elastography (Fibroscan) as surrogates for liver biopsy. These tests are increasingly coming into clinical use, but have not achieved the same status as liver biopsy. Clinical information can also help refine prognosis and inform the decision to treat. Risk factors for accelerated fibrosis include: age at infection >40, daily alcohol consumption, immunosuppression, increased body mass index, male gender, elevated ALT, and coinfection with hepatitis B or HIV. Hare's study evaluated selected adverse prognostic features. Surprisingly, non-treated patients were more commonly hepatitis B and HIV positive. Data on severity of hepatitis B, including transaminase levels, hepatitis B DNA, and hepatitis B serology were not provided. Therefore, it is not possible to determine whether patients with actively replicating disease were less likely to receive treatment. More concerning is the HIV data. HIV should lower the threshold for treating hepatitis C, as HIV coinfection leads to more rapid progression to cirrhosis. It is possible that physicians may have planned to stabilize HIV drug regimens


Blended learning is a concept that has emerged with the onset of e‐learning, or learning that is delivered across the Internet. This type of learning combines more traditional methods of teaching – such as instructor‐led classes held in a physical classroom – with Internet‐delivered content that is learner‐driven and self‐paced. This article looks briefly at the benefits of instructor‐led training and e‐learning, and describes the key elements of a learning organisation. It goes on to explain how e‐learning was effectively incorporated into a six‐month leadership development programme at a global organisation of 3,000 employees to enhance the instructor‐led content and overall programme results. Such results included an increased sense of teamwork and camaraderie, establishment of common concepts and language, and greater efficiency in "jump‐starting" group learning.


•Data Collection: Describe SON simulation efforts •Advocacy: Promote simulation as a problem-based and evidence-based educational approach •Evaluation: Assure quality of SON simulation modules. •Integration: Coordinate integration of essential Baccalaureate and Masters Education (AACN) clinical requirements into graduate and undergraduate curricula. PURPOSE of SEGUE •1994: High fidelity human simulation (HFHS) integrated into the School of Nursing graduate curriculum (Nurse Anesthesia Program). •1999: Simulation education used in undergraduate program. •2002: School of Nursing Sim Lab opened. •2003-2004: Winter Institute for Simulation, Education, and Research (WISER) opened. •2004: Simulation Effort in Graduate and Undergraduate Education (SEGUE) at the School of Nursing convened. •Total sim education hours increased ~22 X since 2002 (~500 hrs) to 2005 (~11,500 hrs) •Number of hours/student = 16.7 in 2005 •56.5% (593/1050) of students will participate in Simulation Modules in 2005 •133 different scenarios are currently used in SON Sim Modules


This paper investigates the relationship between information and individual preferences over income redistribution. The Rawlsian "Veil of Ignorance" argument for justifying income redistribution is examined. We find no evidence of the insurance motive behind the Veil of Ignorance.


The remarkable contrasts between El Niño and La Niña in the East/Southeast Asia region and the western Pacific region are reported. One is that the lightning flash rate in the East/Southeast Asia region shows a clear inverse correlation with the Southern Oscillation Index (SOI). The lightning activity increases during the El Niño period and decrease during the La Niña period in this area. The other is that the contrast of the areal distribution of the variation of the flash rate in the western Pacific region. During the El Niño period the moist air from the ocean is warmed over the land, and that makes strong updrafts in high‐pressure systems over the oceanic area. As a result, well‐developed cumulonimbus with frequent lightning activity is observed in the coastal area. During the La Niña period, low‐pressure systems on the land cause the increase of rainfall frequency with less lightning activity.


Abstract To minimize attack on metals during cleaning with acid solutions containing dissolved iron in the ferric state, both hydrogen evolution corrosion and ferric ion corrosion must be effectively inhibited. There are many inhibitors which effectively reduce hydrogen evolution corrosion, but these have a relatively small effect on ferric ion corrosion. Data are provided which show the synergistic action of certain substituted thioureas and thioamides with certain alkali metal and amine alkyl or alkyl-aryl sulfonates and sulfonated esters in effectively inhibiting both ferric ion and hydrogen evolution corrosion on ferrous and other metals during exposure to a variety of acids. Potentiostatic measurements indicate that inhibition is a result of retardation of cathodic reactions.


Identification of SARS-CoV-2 mutations allows tracking across geographic regions to inform public health responses and may elucidate the role of strain variability in COVID-19 clinical syndromes.


The Chinese culture is not the seal culture.She has the glorious vitality,beause she has the opening the nature and its own characteristic. This article first pointed out the wrong manner about external culture、 the native place culture and the traditional culture modernization; then has analyzed the relation of external cultural and the native place culture,the necessity to realize traditional culture modernization and how to realize; finally pointed out at the globalization background face the multicultural culture,we must process their realationship and try to realize the culture the traditional culture modernization.


Abstract The paper presents a moving horizon l 2 control approach for the class of linear parameter-varying systems. By solving online a convex optimization problem subject to linear matrix inequality constraints the l 2 gain from the energy bounded external disturbance to the performance output is minimized at each sampling instant. The approach guarantees satisfaction of state and input constraints and it is shown that the online recalculation of the control law improves disturbance attenuation significantly when compared to a static control law.


A performance-based contract was applied the past 7 years in Indonesia, as an effort to create a fair and optimal risk sharing between the government and private sector. Performance-based contracts could potentially give rise to various benefits to the road management, contractor and road user. The benefit of the application of PBC is the declining cost, especially life cycle cost, ensuring the road handling and road performance. This indicates that the financial aspect and performance of the services can be a major consideration for a switch from the application of the traditional approach to the PBC. In addition to the benefits of the economic aspects, the success of PBC also determined from various aspects that influence each other, namely the social aspect and environmental aspects. This paper analyses the sustainability of PBC implementation that suits the Indonesian national road management system based on literature review. Sustainability of implementing PBC in Indonesia should pay attention to the main effort to success PBC, namely: long-term contract, a degree of freedom of the contractor in innovation, a balanced risk among owner and private sector, fairness reward and punishment, developing robust models to optimize maintenance strategies, increase database of specified the road network, maintain performance level before implementing long-term PBC. And must be able to resist the influence of high political effect, weak implementation of law rule. Keyword-delivery system, performance-based contract, risk sharing, national road


This paper focuses on analyzing the cash supply network, in which the central bank – as an institutional member – acts as a key influencing node/party. By analyzing the case study example of the Hungarian cash supply, the paper introduces the different kinds of special network patterns that can appear in cases, when the network exists in an institutional (B2A) context and the institutional network member has a special regulatory role in influencing the manner of other business network members. The research findings are based on the application of the case study method. One case will be analyzed that focuses on introducing the main features of the Hungarian cash supply network and the behavior of its key members [central bank (the institutional one); cash logistic providers, commercial banks, post office, retail chains (business ones)]. From managerial point, the analyzed case provides evidences that influencing and interplaying network effects are valid for an institutional member as well, even if it has "special rights" to influence the basic network processes and structure.


Objective: To analyse the application and results of coronary intervention in our department of cardiology from May 2001 to May 2004. Methods: The data of coronary intervention including the selection for PTCA and stents, performing technique, success rate, major complications and restenosis in our department of cardiology from May 2001 to May 2004 were collected and analysed retrospectively. Results: In the 132 patients with coronary intervention, 86 cases with 192 lesions, including 15 type A, 107 type B, 70 type C were dilated. 45 patients with 110 lesions were implanted stents. Stent-implanting rate was 52.3% (45/86). All of the cases were followed up for 2-36 months. No acute thrombosis happened. No acute myocardial infarction, emergency bypass and death occurred with the procedure. There were 2 patients (among the 45 patients) were found restenosis within the stents, the found restenosis rate was 4.4% (2/45) up till now. Following with the time and coronary angiography, we believe the restenosis rate will increasing. Conclusion: Limited data of our department suggest that: ① The selective coronary angiography is the main method for the diagnosis of coronary heart disease (CHD). ② PTCA and implanted stents is the first option for treatment of CHD. ③ The type C lesion of the CHD is also the indication of PTCA and stents. ④ Restenosis rate of implanted stents was 4.4%. ⑤ Total occlusion of CHD was not the contraindiction of the percutaneous coronary intervention treatment. About the long effect of the implanted stents in coronary lesion is still under investigating.;


SUMMARY- A mathematical model of multi phase transport of heat, mass, and reacting chemical species in a porous media is developed. The model is appropriate for describing many of the reactions that take place in a geothermal reservoir. This model leads to the separation of transport terms from reaction in the equations for chemical species concentration. A numerical method for the solution of the transport equations is developed based on the integrated finite difference method. Four example problems representative of those of interest in geothermal reservoirs are solved. These examples consider up to 14 chemical species and 9 chemical reactions amongst these species.


Objective: Saxagliptin is an orally anti-diabetic drug. It has an oral bioavailability of 50% due to first pass hepatic metabolism. To achieve sustained action of drug, reduce dosing frequency, bypass the hepatic first pass effect and improve bioavailability, buccal films formulation was planned.
Methods: Compatibility of the drug with the excipients was studied with the help of FTIR. 23 factorial design was planned using concentration of Sodium alginate, concentration of Chitosan and PEG 400. Solvent casting method was used for the fabrication of films. Weight, thickness, surface pH, mucoadhesive strength, in vitro residence time, % swelling and % drug release were evaluated for the prepared film formulations.
Results: All the films were found have surface pH close to neutral pH and were found to have content uniformity. Mucoadhesive strength was found to increase with increase in concentration of Chitosan. Drug release is more controlled by the high swelling film formers than sodium alginate. Among the film formers, though swelling is more, % drug release is also more from sodium alginate and Chitosan films because of its ionic nature and more solubility.
Conclusion: Because of high mucoadhesive strength and more % drug release, combination of Sodium alginate with Chitosan film formulations was selected.
 Key Words: Saxagliptin, Buccal films


Objective
To search for the potential novel mutation site and to discuss related clinical characteristics by collecting detailed information and testing the gene of a family with highly suspected type 7 maturity-onset diabetes of the young (MODY7).

Methods
The gene test was conducted in a 28-year-old female patient with a 20-year course of non-ketosis-prone diabetes, with non-effective long-term insulin treatment, and a 3-generation family history of diabetes, and the patient was found to carry KLF11 gene mutation. Thus, the clinical data of family members were collected and investigated, and the pathogenic gene was tested. Firstly, the proband was searched for pathogenic genes by chip-capture high-throughput sequencing method. Then the mutation sites were verified by Sanger sequencing technology, and other family members were searched for the same mutation sites by the Sanger sequencing technology.

Results
A total of two members of the family was found to have heterozygous mutation of KLF11 gene: c. 920C>T (No. 920 nucleotide of the coding region mutated from cytosine to thymine), resulting in the change of corresponding amino acid p. P307L (No. 307 amino acid changed from proline to leucine), which was a missense mutation and was consistent with their clinical diagnosis of diabetes.

Conclusions
The family in this study had a family history of diabetes caused by the missense mutation of KLF11 gene. This is the first report of the mutation site of c. 920C >T (p.P307l), which may be a new mutation site of MODY7.

Key words:
Maturity-onset diabetes of the young, type 7; Transcription factor KLF11; Missense mutation


This paper presents a fully automatic system for soccer game summarization. The system takes audio-visual content as an input, and builds on the integration of two independent but complementary contributions (i) to identify crucial periods of the soccer game in a fully automatic way, and (ii) to summarize the soccer game as a function of individual narrative preferences of the user. The process involves both audio and video analysis, and handles the personalized summarization challenge as a resource allocation problem. Experiments on real-life broadcasted content demonstrate the relevance and the computational efficiency of our integrated approach.


One hundred years ago Emperor Nicholas I of Russia, called by his detractors "the gendarme of Europe" and by his admirers "the pillar of conservatism/' died in the midst of the Crimean War. And with him died an era often labelled a police state by radical critics. Yet it was precisely in this era that Russian literature, long a captive of foreign influences, emerged as a national expression of the genius of the Russian people. And in this beginning of the true Golden Age of Russian letters, Alexander Pushkin, often called the Shakespeare of Russia, played not only the leading but also the pioneering role. Ever since his tragic death after a duel in 1837, which preceded the death of Nicholas I by eighteen years, opinion in Russia and elsewhere has been divided on the question whether Pushkin was a liberal or a conservative. Volumes have been written on the subject; scholars have investigated every phase of Pushkin's life, every line of his verse and prose, invariably arriving at one or the other of the two debated and debatable conclusions. To one group Pushkin was a liberal, a republican, a lover of liberty, and a hater of tyrants; to the other, the great poet was naturally and essentially conservative, supporting the established absolute order in Russia by virtue of his birth, of his education, of his position in Russian society. It is true that each group was able to find both in Pushkin's writings and in his life enough material for the support of its particular thesis, thus carving two different human beings out of the flesh and blood that was Pushkin. Yet, it has always seemed to the author that Pushkin combined in himself a perfect blend of liberal ardour and of conservative wisdom, the two essential elements necessary for the making of a national poet. As such, he can best be understood when one reviews his relationships with the two sovereigns in whose reigns he livedthe once liberal Alexander I and the always conservative Nicholas I.


WSSV were incubated with concentrations of disinfectant special tetraammonium complex iodine at 37℃ for 2h,and then inoculated to animal model fresh water crawfishes to examine the effect of this disinfectant againt shrimp WSSV.It demonstrated that at concentrations of 40 μg/ml and 60 μg/ml,30% and 60% of the infected crawfishes lived,respectively,while the positive controls 100% died.


(73) Assignee: Council of Scientific and Industrial Research, New Delhi (IN) Primary Examiner Wayne A. Langel (74) Attorney, Agent, or Firm-Ladas & Parry (*) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 (57) ABSTRACT U.S.C. 154(b) by 0 days. A process for the continuous production of hydrogen from methane and/or natural gas and/or methane-rich hydrocar (21) Appl. No.: 09/652,377 bons and Steam at low temperature, using a Solid catalyst comprising group VIII metal oxide(s) in two parallel (22) Filed: Aug. 31, 2000 reactors, comprising reducing the Solid catalyst in both the (51) Int. Cl. .................................................. C01B3/26 reactors by contacting the catalyst with a gaseous feed (52) U.S. CI. 423/652; 423/653; 423/654 comprising a reducing agent, contacting a first gaseous feed (58) Field of search. .423.652,653 comprising methane and/or natural gas and/or methane rich hydrocarbons, Simultaneously contacting a Second gaseous 423/654; 252/373 feed comprising Steam called Feed-B with the Solid catalyst (56) References Cited reduced in Step-i in a Second reactor. While regularly Switch ing over the two feeds, Feed-A arid Feed-B, between the two U.S. PATENT DOCUMENTS parallel reactors to obtain a mixed product Stream compris


Mobile applications play an important role in the economy today and there is an increasing trend for app enablement on multiple platforms. However, creating, distributing, and maintaining an application remain expert tasks. Even for software developers, the process can be error-prone and resource-consuming, especially when targeting different platforms simultaneously. Researchers have proposed several frameworks to facilitate cross-platform app development, but little attention has been paid to non-technical users. In this paper, we described the Flow framework, which takes the advantage of domain-specific languages to enable no-code specification for app modeling. The cloud-native coordination mechanism further supports non-technical users to execute, monitor, and maintain apps for any target platforms. User evaluations were conducted to assess the usability and user experience with the system. The results indicated that users can develop apps in Flow with ease, but the prototype could be optimized to reduce learning time and workload.


Purpose : Several studies found that visual straylight does as a rule not return to the level normal for young eyes after cataract extraction and IOL implantation (J Cataract Refract Surg. 41(7):1406-15). Ten percent of pseudophakic patients su er from disabilitating straylight elevation. The reason of the observed increase is unknown. Although it has been reported that scattering of a new intraocular lens (IOL) is low, this may change once the IOL is implanted in the eye. In the present study light scattering expressed in term of straylight of explanted IOLs was evaluated.


Classical results on asymptotic distribution of the likeli- hood ratio test statistic are extended to multipopulation setting. The as- sertions include a statement on asymptotic distribution in the case of linear hypotheses and a statement on asymptotic distribution for the hypothe- ses approximable by cones. The later framework includes usual smooth hypotheses and is dealt with under validity of local alternatives.


Today, single-pass Free-Electron Lasers (FEL) produced a highly bright radiation, the Self Amplified Spontaneous Emission (SASE), which spectral and temporal profiles are composed of a series of spikes. We demonstrate here the strong and coherent amplification of the 5 harmonic of a Ti: Sa laser (800 nm, 10 Hz, 100 fs) generated in a gas cell, i.e. 160 nm, by the SCSS (SPring-8 Compact SASE Source, Japan) Test Accelerator FEL. This is obtained by overlapping transversally, spectrally and temporally the external harmonic source in the in-vacuum undulator with the electron beam (150 MeV, 10 Hz, 1 ps). With only one undulator section, the 160 nm seeded emission achieves three orders of magnitude higher intensity than the unseeded one, and presents a quasi perfect Gaussian shape in the spectral distribution. This spectacular phenomenon is associated to the generation of intense and coherent Non Linear Harmonics (NLH) at 54 nm and 32 nm. Finally, in view of the low seed level required, such amplification associated to NLH schemes would allow the generation of fully coherent soft X-ray radiations down to the "water window".


The effects of constraints-external conditions imposed on but not inherent in the dataare subtle, and they are as yet insufficiently understood. In line constraint arises when the character states of each Operational Taxonomical Unit are made to add up to some constant, as might be the case with percentage data. A simple transform is indicated. Cross constraint on a classification of OTUs would arise as a result of operations like row standardization. It shows up as a tendency for correlations to go negative, and such standardizations are best avoided if possible. Numerical taxonomic techniques seem to be engaged not in classifying things, but in analysing strings of numbers, and in a certain sense are numerical models of the things. To make inferences, about the things from analysis of the numbers, we must be sure then that our model is both sufficient, at least for the purposes we have set our classification, and also either undistorted, or, at least, distorted in a way we understand. Types of distortion introduced into the model by the process of measurement, or in the preparation of the data, but at any rate external to the thing, may be called constraints. Two types are examined in this paper, and both are named according to, their relation to, the data strings: In-line constraint arises when the elements of each string are forced to add up to some constant value. Cross constraint obtains when the sum of corresponding elements from each string is required to be a constant. Ordinarily, in numerical taxonomy, each Operational Taxonomical Unit (OTU) is modelled by a string of numbers arranged in a column, each character by a row. If the characters have been standardized, row sums are constant, and this is cross constraint on the relation between OTUs. But if R-type analysis of the relations between rows was of interest, the data strings would be the rows, each of which would be in-line constrained after row standardization. A chemical analysis represents a case of constraint which is inherent in the data. The sum of constituents in each sample must be 100%, so that samples are in-line constrained, and the relation between constituents is cross constrained. Other types of distortion, for example the partial logical correlations of Sokal and Sneath (1963), may also exist in the model, and may for taxonomic work be more important. But in two cases that drew my attention to constraints, namely the problem of discriminating explosions from earthquakes biy multivariate analysis of the information on the seismogram, and the problem of classifying rock samples by their chemical constitution, the effects of constraint have proved to be both subtle and far reaching. They should always be considered in assessing the reliability of a classification, and because constraint enters at the earliest stage, the effects will be felt in every method of multivariate analysis. IN-LINE CONSTRAINT AND THE


Axial field permanent magnet machines are gaining wider acceptance day after day due to their advantages over the corresponding radial field machines. Concentrated winding are the choice whenever the simple manufacturing and the low-cost maintenance are the main concerns. The designer of such machine has the freedom to choose any number of coils and magnets. The first part of the paper introduces definite guidelines that help the designer choose a proper combination between number of magnets and number of concentrated coils to get balanced multi-phase voltage waveforms which is a must for a multi-phase generator. The second part of the paper investigates the harmonic reduction of the generator output voltage waveform. The main concern is given to the coil design to achieve that goal by selecting a proper coil span for a certain pole pitch. The paper proposes derived equations to calculate the minimum and maximum allowed values of the coil span to help the designer select a proper value. The double-rotor single-ironless-stator construction is taken as a model to develop the proposed equations and guidelines. Three-dimensional finite element method (3D-FEM) is used to simulate the output voltage of the studied generators. The effectiveness of the proposed equations and guidelines is validated using both 3D-FEM and experimental results.


Resultsrespiratory artifacts, Fourier regressors up to order 2 were associated with statistically significant clusters in all subjects. In some subjects, even higher-order regressors up to order 5 were also significant. For cardiac artifacts, Fourier regressors up to order 7 were significant in all subjects, with higher-order regressors also significant in some subjects up to order 10. The effect of the high-order terms was widespread; the percentage volume with a significant effect was 23% for respiratory regressors of order greater than 2, and 99% for cardiac regressors of order greater than 2. After removing these common fluctuations across the respiratory and cardiac cycles, a principal component analysis revealed that 69% of the studied brain voxels showed a correlation coefficient greater than 0.25 between the respiratory signal and the amplitude of the first principal component of the cardiac residuals (see Figure 1). This indicates that cardiac fluctuations were modulated by the respiration. In a GLM analysis, cardiac regressors of Fourier orders up to 7 and modulated by the respiratory signal were associated with statistically significant fMRI clusters accounting for an average of 81% of the studied brain volume. The addition of these modulation regressors resulted in small, but statistically significant (p<0.05) increases in activation volumes (average 1.5%) and t-values (average 5.4%) related to the visual paradigm. Discussion The fMRI signal is confounded by significant cardiac and respiratory artifacts. These artifacts are aliased in standard fMRI acquisitions, but the current study shows that high-order harmonics account for a significant amount of signal variance and require a high temporal sampling rate for their adequate characterization and removal. Additionally, fMRI cardiac fluctuations were found to be significantly correlated with the respiratory amplitude in widespread areas. The modeling of this modulation effect only resulted in a modest increase in sensitivity for the detection of the BOLD response to the slow visual paradigm, but this could potentially have a higher impact for faster event-related paradigms near the respiratory frequency.


For 0 < x < 1 let [0,a 1 (x),a 2 (x),...] be the continued fraction expansion of x. Write L N (x) = max a n (x). We construct some numbers x's with lim inf N -1 L n (x)log log N = 1/log 2 N→∞.


The British Royal Army Medical Corps was entirely unprepared for the scale of the slaughter in Northern France during the First World War. The introduction of devastating weapons, coupled with the stalemate of trench warfare led to horrifi c facial injuries for countless soldiers on the Western Front. Surgeons had not previously been faced with these new injuries – noses, ears, eyes and jaws sheared off and scooped out by hot, spinning shrapnel laced with muddy bacteria from the French soil. Despite their best efforts, many men were left horribly disfi gured for life. 'Man ' s ability to destroy has always been one step ahead of his ability to reconstruct . . . ', and from these devastating injuries a young New Zealander named Harold Delf Gillies pioneered a new kind of surgery. Gillies approach was unique because he was interested in restoring aesthetics as well as function. He was driven by the idea that the surgeon should be imaginative and creative, like an artist – 'within us all there is an overwhelming urge to change something ugly and useless into some other thing more beautiful and more functional'. He performed more 11,000 operations on over 5,000 men by the end of the war, and perfected many techniques of plastic surgery including the pedicled tube fl ap. We present a short biography of Sir Harold Delf Gillies, followed by examples of his most important work, including three case reports of facial reconstructions, all highlighted with detailed preoperative and postoperative black and white photography.


The natural heterogeneity of soil sustains a dynamic balance between environmental conditions and the residents of the microbiota. In this context, the objective of our work was to identify and quantify distinct groups of microorganisms in winter (2014) and summer (2015), in an Oxisol cultivated for fifteen years with no-tillage system in the Cerrado biome. The experimental design was randomized blocks in a factorial scheme (3x3) with three cover crops (brachiaria, millet and crotalaria) evaluated at three depths (00.05, 0.05-0.1 and 0.1-0.2 m), with four replications in both seasons (winter and summer),. Endospore-forming bacteria, actinomycetes, yeasts, phosphate solubilizing microorganisms and cellulolytic microorganisms were evaluated. Among the studied cover crops, millet presented superior populations of endospore-forming bacteria in winter, and actinomycetes in summer. The populations of other microorganisms were not different among cover crops in the same season. The population of phosphate solubilizing microorganisms did not differ between seasons, indicating that these microorganisms are less vulnerable to seasonal variations in no-tillage system. In winter, smaller populations of endospore-forming bacteria, yeasts, and actinomycetes were observed with increasing depth in the soil. In summer only the population of endospore-forming bacteria decreased with soil depth. Soil depth did not affect the population of cellulolytic microorganisms under on-tillage system. Our findings suggest that millet is the best fallow cover crop for no-tillage system.


In order to a priori find the mode of conversion of a structure from imperfection sensitivity to insensitivity in the course of sensitivity analysis of the initial postbuckling path (cf. [2]), terms appearing in the consistently linearized eigenvalue problem (cf. [1]) are studied. Two main classes can be identified (cf. [4]). The first one is characterized by the restriction of the prebuckling deformations to axial deformations. For this class, the quality of the aforementioned conversion is better than the one for the other class, for which the above restriction does not hold. (© 2009 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)


Although American and Japanese education is different, teachers can use characteristics of each to improve schooling, say these writers, who report here the results of their survey of Japanese, American, and Australian educators.


We have calculated the specific surface energy of the faces of n-paraffin crystals with an orthorhombic structure. An expression for the energy of formation of the surface of a crystalline cluster has been obtained


The medical insurance system for persons of advanced age,as an important part of Japan's medical insurance system,takes payments by workers in office and financial transfer payments as main fund.The system is essentially a kind of medical welfare for persons of advanced age and had hidden trouble at the beginning of establishment of the system.With the aging of population becoming increasingly severe and the rate of birth falling,the system has been a heavy social burden to workers in office,and medical insurance finance has been in a difficult position.Japanese Government reforms medical insurance system for persons of advanced age to win national trust and establish sustainable medical insurance system.However,Japan's medical insurance reform is not optimistic at all because of rapid aging of population,falling rate of birth,economic development at low speed,and national health consciousness enhancement.This is of significance to China's medical insurance system reform.


After the description of the western park developing history,it illustrates the necessity that the western modern park scenery should develop in generalizational direction.It shows the meaning of the unit of heaven and man in modern parks and emphasizes the idea that the western modern landscape should be users-oriented,which can enlighten the park development in our country.


In chapter 1 of this study the relationship between spatial, chemical, and biological factors and their influence on mercury concentrations in walleye were examined. Water, sediment, and fish tissue samples were collected in the summer of the 2008 from 5 lakes near Aroland First Nation, in Nortwesthern, Ontario, Canada and analyzed for metals, mercury, pH, and alkalinity. Arc GIS was used to extract spatial data from base maps and digital elevation models, in order to calculate lake area, watershed area, and wetland area for each study lake. Hg concentrations in fish tissue were compared between lakes using a standardized length using an ANCOV A. The test proved that a significant difference was present (p=O.OOOO with 95% confidence intervals). Walleye (Sander vitreum) from Melchett Lake had the highest levels of mercury with a mean concentration of 0,5505ug/g, while Esnagami had the lowest at 0.2228 ug/g. A nonparametric Kruskal-Wallis ANOVA compared ranks of concentrations of chemical variables associated with Hg, between lakes. Melchett Lake statistically ranked the highest in DOC concentrations and lowest in alkalinity and pH (second lowest). Esangami ranked lowest in DOC concentrations, and highest for alkalinity and pH, suggesting that a high DOC concentration and low alkalinity in Melchett Lake helped increase mercury concentrations within fish. A backward stepwise multiple regression was performed on all biological, chemical and spatial data to isolate variables that contribute most to Hg concentration in Walleye from the entire study area. Wetland area (�=6.439), fish length ( �=0.559), watershed area (�=-5.797), and % wetlands (�=-1.26) were significant predictors of Hg


Considerable disagreement has developed as to what factors determine the quantities of tax-exempts held by commercial banks and property insurance companies. Several studies, Galper and Petersen [4], Rosenbloom [10] and Silber [11] have argued that the demand by commercial banks is largely determined as a residual. That is, any investible funds in excess of bank reserve, liquidity and loan needs are used to purchase tax-exempts. While not necessarily disputing the importance of such factors, others have found that relative yields on taxable and tax-exempt securities are an important determinant of demand. Fortune [2] and Friedman [3], respectively, allocate bank residual funds and total funds of property insurance companies on this basis. The residual funds theory is not based on profit-maximizing behavior and is clearly inconsistent with observed commercial bank purchases of tax-exempts in 1975 and 1976. The combination of massive reintermediation of deposits and repayment of business loans would have been expected to result in substantial bank purchases. In fact, holdings of tax-exempts increased by less in the two year


Free lipase from Candida rugosa was used for the synthesis of butyl butyrate by direct esterification of butyric acid and butyl alcohol. A full factorial experimental design (24) was employed to determine the effect of alcohol to acid ratio (1: 0.5-2.5), water adsorbent concentration (0-20%), enzyme concentration (40-80 mg) and incubation temperature (30-60 °C) on the esterification yield. Water adsorbent concentration has been found to be the most significant factor on the esterification reaction and its influence was negative. The extent of esterification was higher for substrates containing acid in excess even with a low enzyme concentration of 40 mg and 50% conversion was observed. The maximum predicted values for butyl butyrate yield (92.67%) can be attained with substrate containing acid in excess (molar ratio alcohol to acid 1:2.5), 80 mg enzyme concentration in the absence of water adsorbent at temperature incubation of 30 °C.


In the process of China's socialism modernization drive,Deng Xiaoping had carried on a fruitful exploration to socialism harmonious social attributes;combing Deng Xiaoping's theoretical contribution to the harmonious society will advance our understanding of the harmonious society,and guide us to boost the construction of the harmonious socialist society.


Steady spray jets are considered from single cylindrical orifices under conditions of direct fuel injection in internal combustion engines, but at room temperature. Computations were made with a two-dimensional unsteady model that uses atomization results as nozzle exit boundary conditions, a k-epsilon submodel for gas turbulence, and a stochastic algorithm to compute drop events, including collisions and coalescence. Centerline velocity decay, spray width, average drop velocity distributions and standard deviation and skewness and flatness of the drop velocity distribution are compared at several axial and radial locations with corresponding laser Doppler velocimetry data from sprays at three different conditions. Agreement is very good with mean quantities, but the computed standard deviation of the drop velocity distribution (i.e., the drop velocity fluctuation) is generally smaller than the measured one. These nonvaporizing sprays achieve a structure that is very similar to that of fully developed incompressible jets, but 5-10 times further downstream. After development, the drops have little influence on the gas, but the gas controls the motion of the drops.


With so much information and so many systems available to handle it, finding the right solutions for your units can get complicated. Start with the basics of nurse communication, then find your best fit.


In this article we analysis the multi constrained quality of service routing (QoSR)model and a new OoSR algorithm based on the combination of the simulated annealing algorithm and the cultured algorithm is proposed. The cultural algorithm has a strong macro evolution capability, by using of this feature the simulated annealing algorithm is incorporated into the framework of the culture algorithm. The simulated annealing algorithm completes the local searching process which converts the individual solution to the neighborhood and transfers the optimal solution set to the belief space of the cultural algorithm. The belief space can guide the evolution of the next individual generation after updating. The simulation experiment demonstrates that the algorithm puts up a good performance in the QoSR problem.


We have read the remarkable report by Rich N et al. and would like to propose that the tumor growth model of hepatocellular carcinoma (HCC) should be based on a distributed algorithm that includes damping factors and not on a simple exponential function. We would like to share some of our views on growth model of Hepatocellular carcinoma (HCC) that may differ from the valuable report by Rich N and colleagues.


In order to obtain a focusing flattop beam with high uniformity, complex modulation is used to modulate the optical pupil function, and the beam shaping algorithm is designed with a single phase-only spatial light modulator (SLM). Actually, the wavefront aberrations introduced by each element reduce the uniformity of the shaped beam. In particular, the wavefront aberrations in different positions have different effects on this complex modulation algorithm. However, there is a lack of the corresponding error data and robustness analysis. Here, the error and robustness of the complex modulation algorithm are analyzed when different types of aberrations (defocus, astigmatism, and coma) exist in different positions of the shaping optical system, and the mixed area magnification-free (MRAF) algorithm is used as a reference for comparison. The results show that coma has the greatest effect on the beam shaping quality. It is also proved that the impact on the beam quality when there are aberrations in the laser and beam expansion system is greater than those in the SLM and the focusing lens for the complex modulation algorithm, which is different from the MRAF case.


ABSTRACT In this article, the preparation of microencapsulated hexadecaol with graphene oxide (GO) shell was realized by Pickering emulsion templating. The microencapsulated phase change materials (MePCMs) were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) analysis, differential scanning calorimetry (DSC), and thermal gravimetric analysis (TGA). The results showed that the MePCMs with 6 wt% GO had high thermal storage capabilities, excellent shape stability during phase change, and enhanced thermal stability due to the existence of a GO shell protecting the core material from leakage and evaporation. The research provides a novel composite PCM with GO for thermal energy storage.


This paper examines the effects of breadth and depth of external knowledge sourcing on the innovativeness of a specific classification of organization, the knowledge intensive entrepreneurial (KIE) firm. This type of firm has been observed as
being critically important to growth and development in modern economies, yet how it uses external knowledge sources for innovation has received little direct attention in the literature. Using data from the EU?s recent AEGIS project, investigating knowledge intensive entrepreneurship in Europe covering just over 4000 entrepreneurial firms, this paper uses fractional logit models, as well as an OLS model based on alternating least squares optimal scaling (ALSOS), to estimate the relationship between breadth and depth of external knowledge sourcing and that of innovative performance of the KIE firm. We find that breadth is curvi-linearly related to innovative performance in KIE firms, but that depth, while related to innovativeness, does not assume this functional form. Additionally, a principal components analysis reveals that non-industry sources of knowledge in the form of state, national, or regional research-based or academic entities, as well as knowledge in the form of academic and trade publications, are statistically significant/relevant as external
sources of knowledge for innovation in KIE firms. Industry sources of knowledge such as clients, customers, and supplier are statistically significant sources only for innovation in goods, not in terms of innovation in services, or novelty of innovations produced. Recommendations for future research and policy implications are provided based on these findings.


ABSTRACT The ecological balance is disturbed by the massive generation of solid waste (red mud) from aluminum industries. It contained various types of metal oxides with different proportions, and it is essential to extract these valuable metals to maintain sustainability. The hydrometallurgical route is applied to extract hematite (α-Fe2O3) from red mud. This route involves leaching, solvent extraction, and precipitation. The α-Fe2O3 is mixed with different weight percentages of CuO to form a heterostructure (CuO/α-Fe2O3). The malachite green (MG) is degraded using the α-Fe2O3-CuO catalyst for photo-Fenton reaction. All the composites are characterised by XRD, FTIR, UV-vis DRS, PL, and electrochemical study. XRD figure confirmed that hematite (α-Fe2O3) is extracted successfully from red mud, and goethite (α-FeOOH) is suppressed. The reducibility nature of CuO, created a synergism between α-Fe2O3 and CuO, which leads to suppression of e−/h+ recombination by proper charge transfer. It is confirmed through PL spectra and electrochemical study (Nyquist plot). 20CuO/α-Fe2O3 showed the maximum degradation (98%) of malachite green (MG). GRAPHICAL ABSTRACT


This study aims to determine the effect of Advertising Creativity, Advertising Attractiveness, Brand Ambassador Credibility, and Trust on buying interest in the Tokopedia application. Researchers used quantitative methods and used Non-Probability sampling technique which was determined based on purposive sampling. Sampling came from 100 respondents of UMG Management Students class 2018-2021 by distributing questionnaires. Tests using the SPSS method, and analysis testing using test instruments, classical assumption tests, and hypothesis testing. The results show that advertising creativity, fish attractiveness, relying on brand ambassadors and trust have a positive and significant effect on buying interest in the Tokopedia application.


In this paper we address single objective real parameter optimization by using differential evolution (DE). L-SHADE is a well-known DE with success history-based adaptation and linear population size reduction. We propose a modified L-SHADE (mL-SHADE), in which three modifications are made: (1) removal of the terminal value, (2) addition of polynomial mutation, and (3) proposal of a memory perturbation mechanism. Performance of the proposed mL-SHADE is verified by using ten benchmark functions in the CEC2019 100-Digit Challenge. The results show that mL-SHADE achieves a higher score than seven state-of-the-art adaptive evolutionary algorithms.


It's not always easy to explain microbial dysbiosis and inflammation, so here are some strategies for talking about these concepts with your patients.


In the article, a mathematical model for determining the parameters of the access road for catastrophic situations on highways passing through the mountainous area is developed. The reliability of the mathematical model is proven by experiment.


Software development process generally includes requirement analysis, design, implementation, and testing phases. The overall process is called Software Development Life Cycle (SDLC). Each of these steps was executed sequentially in earlier times, i.e. the output of a step is used as the input to the following step. This sequential execution is called waterfall process, and since the total duration of SDLC has been increasing, more dynamic models need to be employed in today's software engineering methodologies. V-Shaped model, Spiral model, Incremental or iterative software development model, are some examples of these methodologies. On the other hand, due to the increase in the total number of projects for a company and due to the product variability, reusability aspect has entered into the domain. This aspect gained importance in the recent years, leading to the execution of framework-based models and software product line engineering process. In this study, the above methodologies are analyzed from an economic perspective with respect to their cost models. Reusability will require upfront investment, but the gain will be higher as the number of common software items increases, which are determined in commonality/variability analysis phase. Improvements in SDLC might also require organizational changes to adapt new methodologies. These considerations are discussed along with the cost model analysis, and a cost-evaluation criterion is provided in the paper.


The aim of this study is to present a situation assessment within the framework of a comprehensive study of the social services for people with mental illness in Hungary. After setting the historical background, we describe in detail the current services, their anomalies, and the ongoing implementation of a strategy to deinstitutionalize them.

 We reviewed the related academic literature and systematically collected and elaborated upon legal documents, decisions, and data from national databases.

 We established that a paradigm shift is taking place in the social care of people with mental disorders in Hungary. The lack of human resources, the paternalistic, institution-centered attitude, the mass supply of social services in dilapidated buildings, and the stigmatization of patients are among the greatest problems. Cooperation between the health and social sectors is inadequate and, in the interests of patients, needs to be improved.

 Hungary needs a complex, integrated, health-and-social-care supply system for people living with mental illness, one that takes into account both personal needs and assistance to recovery. In the continuation of the deinstitutionalization process, emphasis should be placed on social sensitization.


Summary The maximal acid output (MAO) was suggested from the endoscopic appearance of the stomach in 105 consecutive patients. The endoscopist had no knowledge of the patient. A significant correlation (r = 0.58) was found between the suggested MAO and the MAO measured in a subsequent secretory test. The comparison of measured and suggested values for MAO and the gradings of the endoscopic diaracteristics, showed that the gastroscopic evaluation of mucosal foldings, injection, mucus covering and artificial bleeding, is of value in predicting acid secretory capacity.


Objective: To study the effects of different lactic acid treatments on pork color and microbial decontamination. Methods: Pork(Longissimus dorsi) was treated (immersed) in different concentrations(1.0%, 1.5%, 2.0%), temperatures (35 ℃, 45℃, 55℃) and duration times of lactic acid grouped by orthogonal test design, with pork color redness a was measured. Escherichia coli and Salmonella spp. were treated by the above two lactic acid treatments respectively. Results: Pork color redness a is not affected significantly (p0.05) by the following lactic acid treatments concentration 1.5%, temperatures 45℃, duration time 60 s, concentration 2.0%, temperatures 35℃, duration time 60 s. The above two lactic acid treatments show same effectiveness to kill Escherichia coli and Salmonella spp. Conclusion: The above two lactic acid treatments can provide be as critical levels of critical control point of HACCP quality control system during chilled pork processing.


Income distribution inequality has always received concerns from all sectors of the society.Recently,income polarization began to receive attention of researchers.The degree of urban-rural income polarization changes with eonomic growth.For the need of comprehensive analysis on the temporal-spatial characteristics of the degree change of urban-rural income polarization in 2000-2009,the authors use the data of 2000 and 2009 and the measure method of degree of income polarization to calculate ER index for all 88 prefecture-level cities firstly.Then the authors divided those 88 cities into four categorical regions based on the results of the degree of urban-rural income polarization in 2000 and 2009 separately,includes serious region,relatively serious region,general region and not obvious region,and divided 88 cities into three categorical regions based on the degree change of urban-rural income polarization,includes accelerated upward trend region,general upward trend region and moderate weakening region.The analyzed results show that the degree of ubran-rural income polarization become more serious in the period of 2000-2009 and there is an accelerated upward trend or general upward trend for the degree change of urban-rural income polarization in most cities.The number of the most serious region is much larger than the number of the general region and not obvious region.Based on the analysis on the spatial distribution of four categorical regions with different degree of polarization in 2000 and 2009 separatively,it is can be seen that there is a significant change about the overall spatial distribution.


The article presents the results of cultivating two-year-old pike-perch in carp ponds in polyculture. The characteristic of hydrochemical indicators in ponds is presented. The data of hydrobiological analysis of experimental ponds are presented. The values of planting densities and fish-breeding biological indicators of two-year-old pike-perch and fish that make up the polyculture are given. The data of statistical analysis indicators of final mass values, minimum allowable length and fatness of two-year-old pike-perch grown in ponds for the purpose of selection in the formed pike-perch repair-broodstock are presented. The material on the ratio of weight and size groups of two-year-old pike-perch is presented. The conclusions are given in which the results of analysis of the fish productivity data of two-year-olds for pike-perch, variability of body weight values, minimum allowable length and fatness of two-year-old pike-perch, distribution of two-year-olds by weight and size groups are presented.


This paper presents the design and realisation of a hybrid, high-accuracy, automated measurement framework. A hybrid measurement system is introduced that has been successfully used to carry out high-accuracy measurements in distributed automation environments. The application of the hybrid measurement system is not limited to such environments, though. It is characterised by monitoring distributed events with low interference and by the usage of global timestamps based on the high-resolution clock of a logic analyser. Furthermore, it exhibits an extensively automated experiment control and data analysis framework. Measurement results gained with the approach are presented as well.


dihydroxyvitamin D 3 is the metabolic product of vitamin D and get more and more wide application in medicine . In this paper we review the recent progress of synthesis by the conversion of natural steroid.


* CONTENTS * 1. Introduction: Indigenous Peoples and Poverty - John-Andrew McNeish and Robyn Eversole * PART 1: INDIGENOUS POVERTY * 2. Overview: Patterns of Indigenous Disadvantage Worldwide - Robyn Eversole * 3. The Conditions of Life and Health for Indigenous Women in Areas of High Marginalization, Chiapas, Mexico - Hector Javier S nchez-P'rez, Guadalupe Vargas Morales and Josep Mar!a Jans * 4. Scarred Landscapes and Tattooed Faces: Poverty, Identity and Land Conflict in a Taiwanese Indigenous Community - Scott Simon * 5. Nutritional Vulnerability in Indigenous Children of the Americas: A Human Rights Issue - Siri Damman * PART 2: INDIGENOUS PEOPLE IN NATION STATES: RIGHTS, CITIZENSHIP, AND SELF-DETERMINATION * 6. Overview: The Right to Self-Determination - John-Andrew NcNeish and Robyn Eversole * 7. Poverty and International Aid among Russia's Indigenous Peoples - Indra Overland * 8. Indigenous Peoples of Southeast Asia: Poverty, Identity and Resistance - Don McCaskill and Jeff Rutherford * 9. Tackling Indigenous Disadvantage in the Twenty-First Century: 'Social Inclusion' and Maori in New Zealand - Louise Humpage * 10. Political Participation and Poverty among Colombian Indigenous Communities, the Case of the Zen and Mokan Peoples- A. Carolina Borda Nio and Dario Mej!a Montalvo * 11. Indigenous Peoples, Poverty, and Self-Determination in Australia, New Zealand, Canada, and the United States - Stephen Cornell * PART 3: INDIGENOUS PEOPLES' PERSPECTIVES ON DEVELOPMENT * 12. Overview: Indigenous Peoples' Perspectives on Development - John-Andrew NcNeish * 13. Ecological Wealth versus Social Poverty: Contradictions of and Perspectives on Indigenous Development in Central America and Mexico - Pablo Alarc n-Ch ires * 14. Indigenous Anti-Poverty Strategies in an Australian Town - Robyn Eversole, Leon Ridgeway and David Mercer * 15. Sami Responses to Poverty in the Nordic Countries - Christian Hicks and nde Somby * 16. Conclusions: Poverty, Peoples, and the Meaning of Change - John-Andrew NcNeish and Robyn Eversole * Index


Abstract Whallon claims to have made a rigorous application of dimensional analysis of variance to the delineation of spatial artifact patterning at the site of Guila Naquitz. Questions are raised here pertaining to replicability and to the cultural formation processes of the archaeological record. These unresolved questions suggest that Whallon's optimistic claims for the utility of dimensional analysis of variance cannot be adequately evaluated at present.


Dielectric properties of ferroelectric-ceramic/metal exhibit extraordinary high values of effective dielectric permittivity. We have prepared BT/Ni ceramics with Ni composition from f = 0 to f = 0.3 and we have studied the dependence of its dielectric permittivity, and its ferroelectric properties under high electric fields. In these composites, the ferroelectric character of the matrix is strongly modified by the metallic particles as a consequence of the large increase of linear dielectric permittivity while the non-linear part remains nearly unchanged. In samples with low or moderate nickel content, ferroelectric switching still can be detected. Samples with Ni concentrations close to the percolation threshold which have giant linear dielectric permittivity, become paraelectric. In these latter, leakage current also plays an important role.


The invention discloses a method for preparing a thermoplastic fiber-hybrid woven composite and is characterized by comprising the following three steps: preparing thermoplastic fasciated yarns, weaving a pre-manufactured composite and molding the woven composite, wherein the thermoplastic wrapping yarns consist of strengthened fibers and thermoplastic resin fibers which are mixed according to the volume by adopting a fiber wrapping technology, the thermoplastic fibers are 40 to 80 volume percent and the strengthened fibers are 20 to 60 volume percent; and then the thermoplastic resin fibers are uniformly covered on the strengthened fibers to form the thermoplastic wrapping yarns. The thermoplastic composite is a big trend in the further composite development and has a bright development prospect.


January 8th is Midwife Day. On this day, it is customary to honor the so-called «midwives». In the history of obstetrics in the first half of the 19th century, the activity of midwives was firmly entrenched namely for women who dominated in obstetric activities due to established views on birth as the female area and the existing kind of «taboo» on «unpopularity» of this specialization among male doctors during the study period. At the same time, the very definition of «midwife» was applied both to those who received a special education, and to «uneducated rural midwives». The midwife in rural areas occupied the main place in maternity rituals and in obstetric practice. In the activities of the midwife, rational and irrational methods of traditional medicine were used. A sociological portrait of a midwife is presented.


This study is devoted to reveal a simple self-healing, diffusive–dissolution-like mechanism of transient pore's closing in a model spherical vesicle. It is based on a novel thermodynamic mechanism invented in terms of structural flux–force relations, with Onsager's coefficients reflecting the mainand cross-effects of nearly one-micrometer-in-diameter pore formation (of linear cross sectional size r) immersed within the membrane of a spherical vesicle of at least several tens of micrometer in its radius (R). The closing nanoscopic limit is given by r → 0. The pore's formation is envisaged as a kind of bending and excess-area bearing (randomly occurring) failure, contrasting with a homogenizing action of the surface tension, trying to recover an even distribution of the elastic energy accumulated in the membrane. The failure yields at random the subsequent transient pore of a certain


The current status was analyzed of employed medical staff in the military hospital,such as weakness of responsibility and consciousness of serving for the soldiers,high turnover rate,the lack of high level talent.And then the author proposed the measures to solve the problems,as motivating their work passions,help them to make out of planning career,mending the salary system and setting up human-oriented management ides.With these efforts,we can promote the medical talent construction and realize the sustainable development of military hospital.


To better understand a competitor's tactical and strategic plans, companies need to take a closer look at competitive intelligence or they risk missing lucrative opportunities. Because of this there is a growing interest in competitive intelligence and intelligence information gathering systems (IIS). This article uses game-theoretic concepts to develop an analytic framework to assess the value of deploying a competitive intelligence gathering information system. Modeling the competitive environment as a game provides a useful approach to study and evaluate competitive strategies given diverse assumptions about the quality of the information known by the players. When determining the value of deploying an IIS, decision makers need to examine three components of the competitive environment: the competitive rules of the game, the state of player knowledge, and the reliability of the information gathered. This framework focuses on competitive environments where the players' state of knowledge (i.e., common versus covert knowledge) and the reliability of the information generated are essential to the decision making process. The article concludes with implications for research and practice.


The differential modulation of the resonance bands in long-period gratings is utilized for simultaneous strain/temperature and strain/refractive index sesning. Cross-sensitivity and measurement inaccuracies are investigated to determine thier influence on dynamic range and system stability.


Disclosed is a leak detection device for connecting a pipe material. The sensing device of the present invention is to be installed for each connection to check whether the contents leaked in real time when the contents are leaked due to the broken connection of the piping material, if the contents leaked due to damage to the piping material, the leaked contents to escape to the outside, When a negative pressure is generated, a cover is formed on the upper side so that air or the like is easily introduced from the outside, and the leaked contents or negative pressure is installed on the inner upper end of the cover to the leaked water, gas, or oil when entering or exiting through the hole. The copper plate is installed to face the inside of the cube to check whether there is an abnormality of the connecting portion, and the connecting line connected with the copper plate is connected to the sensing line exposed to the end of the adjacent tube to connect the entire network to the system. When the connection part is abnormal when connecting through the copper plate A sensing sensor for checking whether there is an abnormality by moistening, and an outer finishing tape on the cover to prevent the cover from being separated by gas pressure or water pressure, and to prevent the contents from leaking between the contact area of the cover or the cover and the outer surface of the piping material. It is configured to include, since the detection line is not directly exposed to the attenuation phenomenon is less generated, since the detection sensor is configured separately from the jump line, the construction is also easy to effect.


The Western ideas had a great impact on the Vietnamese literature in the 20~(th)century.The influence and infusion of the French literature,latinization of the Vietnamese language,development of the press,innovation of genres and rise of various literary schools and notions all marked the emergence and development of the new literature.The Vietnamese literature underwent modernization and revolutionization in the 20~(th) century,and is presently going towards democratization.


North Yorkshire police officers killed in the line of duty were remembered yesterday at a ceremony to mark National Police Memorial Day in Belfast. ...


The article analyzes the acclimatization work carried out, the current state of the food supply and the feasibility of introducing new food items. Lake Balkhash, in the first years of commercial development, was characterized by extreme poverty of the food base, especially the bottom fauna. During the period of planned acclimatization work, 1958–1965, 10 species of valuable food items were introduced into the reservoir. Many species, as expected, settled in the western part of the lake, where they not only expanded the species composition of bentonts, but also increased the feeding capacity of the reservoir — from 1.3 to 20 times. However, with an increase in salinity from west to east, the composition of benthos became poorer and its biomass decreased due to the gradual loss of mysids, corophiids, polychaetes and monodacnae from its composition. At the present stage, the biomass of zoobenthos in the eastern part of Lake Balkhash is 20–40 times lower than the indicators of the western part. To increase feed in Eastern Balkhash in 2012–2014. Experimental work was carried out on the survival in the Balkhash water of euryhaline invertebrates from the Aral Sea — polychaetes and bivalve molluscs. Based on the positive result, a biological justification was developed for the acclimatization of these invertebrates in the lake. Balkhash, but due to lack of funding, the work itself was not carried out. Within the framework of the above program, it is necessary to continue work on the introduction of brackish-water benthic organisms from the Aral Sea, as well as to ensure the feeding needs of juvenile fish throughout the growing season, there is a proposal for the introduction of Calanipeda aquae-dulcis Kritsch into the reservoir. Research on the issues raised in the article is funded by the Ministry of Ecology, Geology and Natural Resources of the Republic of Kazakhstan (Grant No. BR10264205,).


Aesthetic empathy theory focuses on the matter that human beings put subjective consciousness to objective things and pay attention to describing the emotional experiences but neglect to analyze the condition of aesthetic empathy in the course of aesthetic psychological activities.Emotion plays an important role in the operation system and activity of aesthetic psychology,therefore,the process of explaining aesthetic empathy should be started from the aspects of emotional functions.This paper manages to discuss the emotion operation system of empathy on the view of aesthetic.


The problem of cartesian trajectory control of a closed-kinematic chain mechanism robot manipulator with possible space station applications is considered. The study was performed by both computer simulation and experimentation for tracking of three different paths: a straight line, a sinusoid and a circle. Linearization and pole placement methods are employed to design controller gains. Results show that the controllers are robust and there are good agreements between simulation and experimentation. Excellent tracking quality and small overshoots are also evident.


Heart disease prediction is a complex and critical task in the field of medicine, considering the alarming rate at which people succumb to heart-related issues. The rapid advancements in data science offer a promising avenue for processing vast healthcare datasets. Automating the prediction process can help mitigate associated risks and enable timely patient alerts. This study leverages the heart disease dataset from the UCI machine learning repository to develop an automated prediction system. By employing various data mining techniques including Naive Bayes, Decision Tree, Logistic Regression, and Random Forest, the system aims to predict the likelihood of heart disease and categorize the patient's risk level. Through a comprehensive comparative analysis, this paper evaluates the performance of these machine learning algorithms. The experimental results underscore the superiority of the Random Forest algorithm, achieving an impressive accuracy rate of 90.16% in contrast to the other algorithms studied.


This study aims to reveal the attributes of cognitive styles of the African and the East Asian cultures toward understanding cultural basis for perceptual process of product design aesthetics. The study took a cognitivist approach following the categorization task used by Park (2011) based on Chiu's method (1972). In this study, a web-based research was conducted with participants from Africa (n=35) and Japan (n=35) using natural and artificial objects represented in word triads as stimuli. Based on Nisbett's (analytic versus holistic thoughts) and Park's (attribute-oriented and relation-oriented thoughts) cognitive models, the study suggests that difference in cultural cognitive style can shape the perceptual process of aesthetics in product designs. The analysis of the test showed that the African participants showed more tendencies for analyticand attribute-oriented thought than the Japanese respondents. Following this result, the study further seeks to delineate the characteristics of the perceptual process of product design aesthetics among African and Asian cultures. It is expected that this knowledge can foster innovative Kansei approach to design over cultural diversity.


This article introduces the register window technique and stack frame, and analyses the process of the subroutine calls through an example program, taking SPARC v8 for an example.


An exact solvable, realistic model for the description of the Stark effect on a hydrogen atom is presented. The model Hamiltonian is used to calculate polarizability of the hydrogen atom by means of variational‐perturbation theory.


For the last couple of decades consumer decision-making has been of increasing interest for retail as well as for consumer behaviour research. Food shopping constitutes a unique type of shopping behaviour. In comparison to other types of shopping, food is essential to life, and not often are there as many choices to be made in a short period of time as when shopping groceries.The purpose of this dissertation was to advance the knowledge of what influences consumers' choices of grocery stores. More specifically, the main focus has been on how different situations (e.g., type of shopping) influence choices of grocery stores. Five papers, which build on three surveys on how consumers choose grocery stores in Sweden, are included in this dissertation.In the first paper a comprehensive set of ten aggregated attributes that determine store choices were developed. The second paper brought forward five consumer segments (Planning Suburbans, Social Shoppers, Pedestrians, City Dwellers, and Flexibles) based on where and how they shop. In the third paper it was shown that accessibility attributes (e.g., accessibility by car, availability) and attractiveness attributes (e.g., price, service) have different impacts on satisfaction, depending on consumer characteristics and shopping behaviour in supermarkets compared to convenience stores. In the fourth paper the result showed that satisfaction is affected by type of grocery shopping (major versus fill-in shopping) in conjunction with time pressure and which store attributes that are important for satisfaction. It was also shown that the effect of time pressure and type of shopping on satisfaction varied in different consumer segments. In the final paper it was shown that a store has to be more attractive in terms of attributes for a consumer to switch from the grocery store they usually patronage, even if the new store is situated right beside or closer than the consumer's regular grocery store. The view of a "good location" is further developed in this dissertation, arguing that consumers' mental distance to a store – their cognitive proximity – is much more important than the physical place of the store.In sum, this dissertation revealed that the situation is more important than previous research has shown. Depending on the situation, consumers will face different outcomes (different stores) and value different store attributes. Hence, stores need to manage different store attributes depending on which consumer groups the stores want to attract and what situation the consumers are facing. Therefore, consumers' choices of grocery stores are situation-based choices.


The filter (2) has a textile planar structure including longitudinal yarn (5) and transverse yarns (6, 7) that are engaged with each other at crossing points (14) and are fused with each other. The transverse yarns contain an additive that imparts the ability to absorb laser energy, where the transverse yarns are bicomponent yarns that include a core and a casing surrounding the core, and the additive is contained only in the casing. The transverse yarns are brought to a melting temperature at a surface by the absorbed laser energy. Independent claims are also included for the following: (1) a method for manufacturing a forming filter for use in a sheet-forming section of a paper machine (2) a device for manufacturing a forming filter.


The invention provides a filter screen mold. The filter screen mold comprises a fixed mold, a movable mold, a net material which is arranged between the fixed mold and the movable mold, and multiple pins which are arranged on the fixed mold, located at two sides of the net material and used for blocking the edge of the net material. The pins are arranged on the fixed mold and the net material is clamped by the pins so that the net material tightly clings to the fixed mold and thus in net material molding, the technical problem of part disqualification caused by cavity deviation is solved, production efficiency is improved and a production cost is reduced.


Abstracts of papers concerning the geology and geophysics of Mars, volcanism on Mars, the Mars atmosphere, and the long term history of the atmosphere-cap-regolith volatile regime are presented. Formation of the Mars surface, climatology, gravity and magnetism, atmospheric boundary layers, and interpretation of Viking imagery and Earth-based observations are considered.


Patient care and public health in the United States depend on timely and reliable clinical laboratory testing. A third of the roughly 500 million yearly patient visits to health care providers involve at least one laboratory test, and approximately 70% of medical decisions are based upon test results. However, the performance of clinical laboratory testing could be compromised by patient specimens potentially contaminated with highly infectious materials. The importance of biosafety in clinical laboratories was highlighted during the 2014 Ebola crisis, where fears about safety resulted in some institutions refusing or delaying tests on patient specimens, which resulted in delayed diagnoses and contributed to patient deaths.

 In collaboration with subject matter experts from academia, medical centers, and federal institutions, the Centers for Disease Control and Prevention has reviewed the capability of clinical laboratories to safely test patient specimens potentially contaminated with highly infectious materials, like Ebola. Current biosafety guidance for clinical laboratories has been largely based on biosafety practices in research laboratories, so the guidelines do not always correspond to clinical laboratories and may be incomplete or occasionally inconsistent. While essential to patient care, clinical laboratories are also unique environments with specialized equipment, processes, and therefore distinct challenges. Here we discuss the complexity of clinical laboratories and describe how applying current biosafety guidance to clinical laboratories may be difficult and confusing at best or inappropriate and harmful at worst. We describe biosafety gaps and opportunities for improvement in the areas of ethics; risk assessment and management; automated and manual laboratory disciplines; specimen collection, processing, and storage; test utilization; waste management; laboratory personnel training and competency assessment; and accreditation processes.

 These identified gaps in knowledge and practice could inform future research and education in clinical laboratory biosafety.


With the continuous development of distributed applications in the medical sector, gradually systems are more often present to automate the internal processes of medical offices. The aim of this work is to find the advantages of working with the technique of test-driven development to the traditional cycle testing in building systems. To perform the analysis, design and implementation of a Web-based application SCRUM methodology in conjunction with TDD. As part of design, the IEEE-830 standard, which provides guidelines for the collection and analysis of requirements engineering is applied. For analysis between paradigms unit testing and integration testing as a framework for the development of a comparative table in front of TDD are implemented. The research results show that the technique of test-driven development in collaboration with the JUnit framework encompasses not just the testing of the application, but leads the design of it, improving the model coding software. In addition to a fault occurs on a detail with a test which can detect and correct the error in time is maintained. Further acceptance by users cataloging application as reliable, available and effective at the same time to manage the processes for managing medical office shown.


Abstract Extract Madam:-, Fur-chewing is a relatively common apparent behavioural problem of farmed rabbits. Unlike the preparturient doe, who pulls out fur from ventral body surfaces to line her nest, rabbits of either sex which fur-chew, bite off hair from any part of the body which is accessible and may partially denude more than 50% of their body surface. The condition often appears to be self-inflicted, and unlike whisker chewing in mice, or feather plucking in chickens, a rabbit may either chew its own fur or that of others. The condition is a serious problem for commercial producers of rabbit pelts and for those attempting to carry out nutritional studies which require analysis and comparison of food intake and faecal output. For instance, in digestibility studies, fur-chewing constitutes a confounding variable in relation to nitrogen analysis.


Objective: To optimize the extraction technology conditions for Fructus Viticis according to the active components property. Methods: With L9(34) orthogonal test, and with the extraction rate of total flavone and castisin as criteria, the contents of which were determined by UV and HPLC methods, the best extraction technology conditions were optimized. Results:The best extraction technology conditions were as follows: the material was pulverized, refluxed three times of one hour each, and 95% ethanol aqueous solution was used as extraction solvent. Conclusion: The optimized extraction technology is stable, convenient and practical.


Abstract We aimed to compare simultaneous invasive and non-invasive blood pressure (IBP and NIBP) measurements in young, middle and old age using the data from the Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II) database. In total, 23,679 blood pressure measurements were extracted from 742 patients, divided into three groups of young, middle and old age. IBP–NIBP differences in systolic/diastolic blood pressure (SBP/DBP) were 0.1 ± 16.5 mmHg/11.0 ± 12.2 mmHg in young age, –2.9 ± 19.8 mmHg/6.9 ± 17.5 mmHg in middle age and –3.2 ± 29.3 mmHg/8.5 ± 19.8 mmHg in old age. The mean and standard deviation (SD) of invasive systolic blood pressure (ISBP)–non-invasive systolic blood pressure (NISBP) differences increased from young to middle then to old age, and the SD of invasive diastolic blood pressure (IDBP)–non-invasive diastolic blood pressure (NIDBP) differences also increased with age. In young, middle and old age, the correlation coefficients were 0.86, 0.79 and 0.53, respectively, between ISBP and NISBP, and 0.78, 0.78 and 0.41 between IDBP and NIDBP. In conclusion, IBP showed good correlation with NIBP in each age category. The agreement between IBP and NIBP measurements was influenced by age category.


In metaphase II arrested mammalian oocytes (eggs) and cleavage stage embryos the mitochondria are responsible for nearly all ATP production because glycolysis is inactivated. Luciferase assays show that ATP levels in eggs are strictly dependent upon pyruvate and fatty acid oxidation. The level of ATP in eggs appears to be maximal in conventional medium because the addition of extra mitochondrial substrates to eggs does not increase cytosolic ATP. The only clear elevation of ATP is seen at fertilization and is associated with sperm induced Ca2+ oscillations. Our recent findings suggest that the level of ATP modulates events at fertilization.
 At fertilization, the egg is activated by sperm derived PLCzeta which triggers a series of Ca2+ oscillations, with each Ca2+ release event causes by inositol trisphosphate (InsP3). Previous studies have shown that mouse eggs are more sensitive to PLCzeta, and generate higher frequency Ca2+ oscillations, than human eggs. Mouse eggs also generate Ca2+ oscillations and activate in response to Sr2+ that directly stimulates InsP3 receptors. In contrast, human eggs that contain the same type of InsP3 receptors do not generate Ca2+ oscillations in response to Sr2+.
 The difference in sensitivity of Ca2+ release between species can be explained by the fact that mouse eggs are about ten times more sensitive to InsP3 than human eggs. The reason for this difference appears to be due to ATP. The ATP level in unfertilized mouse eggs is about twice that in human eggs. Furthermore, the ability of mouse eggs to Sr2+ medium can be abolished by removing the mitochondrial substrate pyruvate, which reduces the ATP level. Adding back pyruvate to such eggs restores ATP levels promotes Sr2+ induced Ca2+ levels in mouse eggs. These data suggest that the level of ATP, possibly as ATP4-, modulates the sensitivity of the InsP3 receptor and the ability of eggs to generate Ca2+ oscillations. The level of cytosolic ATP may represent a significant 'egg factor' in determining the success of fertilization in humans. Enhancing mitochondrial ATP production could be useful in improving activation and embryo development after fertilization, or after artificial egg activation.
 References:
 Dumollard et al. (2009) Seminar in Cell and Developmental Biology 20, 346-353
 Campbell and Swann (2006) Developmental Biology 298, 225-233
 Storey et al. (2021) Molecular Human Reproduction 27, gaaa086


Background : Obesity is a public health problem affecting 35% of the adult population in the US.A 5-10% weight loss decreases the risk of cardiovascular disease and diabetes mellitus. Diet and exercise have shown to be effective in the treatment of obesity, but adherence is a limitation. Dark chocolate (DC) polyphenols were proven to have beneficial effects on blood pressure, endothelial function, HDL cholesterol, lipoprotein ratios and inflammation markers. Also, it might play a role in improving fat metabolism and satiety; however, its effects on weight loss are still not clear. We propose a protocol to explore the effects of DC associated with hypocaloric diet and exercise on weight loss during a 12-week period in obese adults.  Methods and Design: The study is a randomized controlled trial with 2 parallel arms comparing hypocaloric diet + exercise with hypocaloric diet + exercise + 50g dark chocolate/day during a 12 week period. A total of 408 obese adults (18 to 45 years old) with no comorbidities that could compromise the exercise program will be recruited. Primary outcome is proportion of patients who had 5% or more weight loss after 12 weeks. Secondary outcomes are glucose levels and insulin resistance (HOMA-IR), lipid profile, abdominal circumference, body fat mass (estimated by skinfold thickness) and blood pressure, satiety perception and drop-out rates. Primary outcome (percentage of patients achieving 5% or more weight loss) will be analyzed by chi-square test with an Intention-to-Treat approach.  Conclusions: This phase II randomized controlled trial has the aim to explore the effects of including dark chocolate as an adjuvant to classical therapies (hypocaloric diet and exercise) on weight loss in a 12-week period  Trial registration : the trial will be registered at www.clinicaltrials.gov


A transient ballistics and combustion model is derived to represent the closed vessel experiment that is widely used to characterize the high pressure burning rates of solid propellants. The model is applied to explain why burning rates deduced from the closed vessel are in basic agreement with those measured from an equilibrium strand burner in the case of homogeneous propellants, but differ significantly in the case of nitramine composite propellants. Thermal profile time lag effects become small at high pressure because the burning rates become high. However, the development of the burning surface structure of those nitramine propellants which exhibit shifts in pressure exponent causes the mass burning rate to lag and then exceed the equilibrium value. It is necessary to consider this mechanism in applications dealing with high pressures and pressurization rates.


The GIS technology, Database technology, Water quality evaluation technology, etc. are applied in the development of groundwater environment quality evaluation system, this paper show this. The system can do groundwater quality data management, GIS data management, the statistics and analysis of water quality data, the complex evaluation of groundwater quality, etc., which make the groundwater manager easily find out the trends and spatial distribution of groundwater pollution in time.


KATP channels couple cell metabolic status to the membrane excitability by sensing the cytoplasmic ATP/ADP ratio. Present studies examined how conserved motifs (Walker A (WA), signature sequence (L), and Walker B (WB)) within each NBF of SUR2A bind to Syn-1A to affect its actions on cardiac KATP channels. In vitro binding experiments illustrated that Syn-1A binds cardiac SUR2A at WA and L of NBF-1 and WA, L, and WB of NBF-2. Electrophysiology experiments on stably expressing SUR2A/Kir6.2 cell-lines showed that only L and WB of NBF-1 and all three NBF-2 motifs could abrogate the inhibitory effect of Syn-1A on SUR2A/KATP channels. These results lead me to hypothesize that more independent motif in NBF-2 can bind and abrogate Syn-1A's inhibition than NBF-1 on SUR2A/KATP channels. A corollary postulate is that Syn-1A acts as a scaffold to secure the NBF-1 and -2 in dimer conformation required for SUR2A to modulate Kir6.2 gating.


The mixing and ionization of states of a Rydberg atom subject to a time-dependent electric field is studied by direct integration of the Schoredinger equation. A linearly ramped electric field is used, F(t) = {dot F}t, with ionization modeled by field-dependent widths {Gamma}(F). In the linear Stark regime, hydrogenic levels are coupled by F(t) through the atomic core, parameterized by quantum defects. Amplitudes are evaluated in spherical and parabolic hydrogenic bases, and in the nonhydrogenic adiabatic basis. The integration is performed using a modified divided difference form of the Adam Pece formulas; local extrapolation is also used to increase accuracy. The mixing of the levels is first studied for a single manifold and compared to earlier work. Then the multiple-manifold case is studied for Na atoms initially populated in n {approximately} 25. Probability distributions for the time-evolved states are produced in the different bases, as well as 3-dimensional movies of the evolving and ionizing wave function. Implications for analysis of selective-field ionization signals are discussed.


Response to comments of Referee #1 "Subsoil seismic characterization through Vs30 for future structural assessment of buildings (Ciudad del Carmen, Mexico)" nhess-2020-194 Comments to Author The paper has been written as a technical report, needs to be rewritten, and it should be clear what they want to solve. Like-wise, its results should be presented in terms of a characterization of seismic site effects as a preliminary step for quantification studies of seismic hazard. Some remarks 1. summarizes, usually in one paragraph of 300 the major aspects of the paper in a prescribed sequence that includes: 1) the purpose of the study and the research problem(s) the basic design of the study; major findings or trends found as a result of of


By probing into the mission of translation, this paper analyses the necessity to reproduce the original style in literary translation. Then it elaborates the translatability of literary style from the layers of linguistic, stylistic, literary, cultural and philosophical points of view. On account of all this, it touches upon the relationship between the original style of the author and the translator's own style. At last, it points out the limitations in light of translatability.