Veblen-Wedderburn systems (defined in the next section) are algebraic sy terns tha t may be used to coordinatize affine planes and thereby proiecti~ planes. Such planes may be characterized by the fact tha t they satisfy a certa geometric configuration, Hall's Theorem L [2]. Conversely, all planes satisfyii Theorem L, which are not Desarguesian, give rise to many non-isomorph Veblen-Wedderburn systems. The reader who is unfamiliar with these resul will find a very readable account of them in the Slaught Memorial Papers N 4, "Contributions to Geometry" (Am. Math. Month. 62 (1955), pt. II) in paper by R. H. Bruck entitled "Recent Advances in Euclidean Plane Geometry One of the problems is to determine all Veblen-Wedderburn planes of a giw order. I t turns out that the best way of handling this is to determine all Veble Wedderburn systems first. The case of 16 elements is the smallest one requiril the aid of a computer. Considerable mathematical theory [Theorems 1 and below] is required, however, before the computer is called into play. A cor plete account of the theory is presented here. However, the task of sorting tl computed Veblen-Wedderburn systems into isomorphic classes and then arran ing them into geometries is too lengthy to be included here. Only the final resul are tabulated. The nucleus of a Veblen-Wedderburn system with 16 elements may be GF(~ GF(4) or GF(16). When the nucleus is GF(16), the plane is Desarguesian ai no other Veblen-Wedder~mrn system gives rise to the plane besides GF(16) itse When the nucleus is GF(4) we determine all possible non-isomorphic Veble Wedderburn systems. I t turns out tha t there are 75 of them and that th~ determine two distinct projective planes P(1) and P(2). P(1) is determined 25 of the Veblen-Wedderburn systems, which include the known Hall syster [2, p. 274]. P(2) is a new plane and in fact five of its 50 Veblen-Wedderbu systems are division rings, representing the first known division rings with elements. The computations were carried out on SwAc. 1 Eventually, a check on tl computations of SwAc was obtained through geometric considerations. Neve theless, invaluable time was saved as a result of the computations. In the case where the nucleus is GF(2) a systematic enumeration of all tl


outdoor entertaining picnics parties and portable feasts is available in our book collection an online access to it is set as public so you can get it instantly. Our digital library spans in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the outdoor entertaining picnics parties and portable feasts is universally compatible with any devices to read.


We aimed to explore the capacity of the combined ratio of biomarkers to predict the recurrence of Stage I–III endometrial cancer (EC).


When disturbance process of periodic signal occurs, Nonlinearity system produce bifurcation behavior which new frequency spectrum derives from every time. After infinite bifurcations , System turns into chaotic status and frequency spectrum become abundant [1]. The paper analysis the frequency spectrum of the Nonlinearity system and present application design method of chaotic Masking Encrypt technique of frequency-hopping using ergodicity , well relativity and white noise statistic character of chaotic sequence which Duffing equation produces.


Aiming at detecting Cl2 gas,this study was made on how to make In-based compound semiconductor oxide gas sensor.The micro-property and sensitivity of In-based gas sensing material were analyzed and its gas sensitive mechanism was also discussed.Adopting constant temperature chemical coprecipitation,the compound oxides such as In-Nb,In-Cd and In-Mg were synthesized,respectively.The products were sintered at 600 ℃ and characterized by the Scanning Electron Microscope(SEM),showing the grain size almost about 50-60 nm.The test results show that the sensitivities of In-Nb,In-Cd and In-Mg materials under the concentration of 50 × 10-6 in Cl2 gas are above 100 times,4 times and 10 times,respectively.The response time of In-Nb,In-Cd and In-Mg materials is about 30,60 and 30 s,and the recovery time less than 2,10 and 2 min,respectively.Among them,the In-Nb material was found to have a relatively high conductivity and ideal sensitivity to Cl2 gas,which showed rather good selectivity and stability,and could detect the minimum concentration of 0.5 × 10-6 with the sensitivity of 2.2,and the upper limit concentration of 500 × 10-6.The power loss of the device is around 220 mW under the heating voltage of 3 V.


Higher-Order Logic (HOL) is based on a small logic kernel, whose only mechanism for extension is the introduction of safe definitions and of non-empty types. Both extensions are often performed in quotient constructions. To ease the work involved with such quotient constructions, we re-implemented in the Isabelle/HOL theorem prover the quotient package by Homeier. In doing so we extended his work in order to deal with compositions of quotients and also specified completely the procedure of lifting theorems from the raw level to the quotient level. The importance for theorem proving is that many formal verifications, in order to be feasible, require a convenient reasoning infrastructure for quotient constructions.


Twenty four‐hour urine samples have been collected 6 monthly for 18 months from 127 normal boys aged between 7·5 and 17 years. Urinary steroid metabolites have been measured by gas‐liquid chromatography and ratios of steroid metabolites used to draw conclusions about likely enzymic activities at each step in the adrenal biosynthetic pathway.


Tulumba dessert is widely preferred in Turkey; however, it cannot be consumed by celiac patients as it includes gluten. It is vital for the diet of these patients to produce different gluten-free products. In this study, buckwheat flour (BWF) and potato starch (PS) concentration, to be used in the gluten free tulumba dessert formulation, was optimised using the response surface methodology. Increasing the ratio of PS in the BWF-PS mixture caused a decrease in the hardness of the dessert samples and an increase in expansion, viscosity, adhesiveness, and yield of both the syrup including and not including samples. When considering the parameters used in the optimisation process, the optimum gluten free dessert formulation was found to be 175.87 g water, 0.13 g carboxy methyl cellulose, 2.20 g soy protein, 68.24 g BWF and 31.76 g PS. Some properties such as crispness and aftertaste of the samples prepared by this formulation were found to be very close to the control sample. However, tulumba desserts that in...


Do workers adjust hours of work in response to capital gains and losses? This paper investigates this question using British panel data on individual employees from 1992 to 2001. It investigates hours of work adjustments to two sources of capital gain: financial windfalls and real housing wealth gains. Significant reductions in hours are found for both men and women in response, in particular, to housing gains. Men appear to increase hours in response to real housing losses, whereas women reduce hours in response to real housing gains. Evidence on hours of work preferences suggests that observed adjustments are only partial responses.


Objective: Familial Mediterranean Fever (FMF) is a disease characterized by recurrent fever and peritonitis. The onset of clinical symptoms and severity of disease in patients with FMF may be different according to the type of mutation. MEFV gene mutations and clinical symptoms were investigated in this study. The relationship between the genotype and phenotype of the disease was evaluated. Material and Methods: 110 patients diagnosed with FMF were included in this study. The first episode age and age at diagnosis were identified. The complaints during an attack were recorded. MEFV gene mutations were determined. The relationship between the type of mutation and mutations groups (homozygous/heterozygous/compound heterozygous) with clinical symptoms were investigated. Results: The most common mutations were M694V (43.6%), followed by V726A (13.6%) and E148Q (10.9%). Chest pain was the most common clinical finding in patients with the M694V/M680I heterozygous mutation (p 0.05). Conclusion: We think that arthritis, growth retardation, and chest pain were associated with the type of mutation during attacks but the age of onset of symptoms was not associated with the type of mutation.


Objective To observe the diagnostic significance of serum nitric oxide (NO) and C-reactive protein (CRP) detections to the treponema pallidum-positive patients. Methods NO and CRP level were measured and compared in 65 treponema pallidum-positive patients and 70 treponema pallidum-negative people. Changes of NO and CRP level were analyzed. Results Statistically significant differences (P 0.01) existed in NO and CRP level between treponema pallidum-positive patients and treponema pallidum-negative people. Treponema pallidum-positive patients had a higher level of NO (P 0.05) and a lower level of CRP (P 0.01) after treatment. Conclusion NO and CRP detection are of important value in the early diagnosis and treatment of treponema pallidum-positive patients.


The utility model discloses a display device, which comprises a display panel, a back frame, a circuit board and a covering film, wherein the display panel is provided with a first base plate and a second base plate, the first base plate is provided with an upper surface, the back frame bearings the display panel and is provided with an outer surface, the circuit board is electrically connected with the display panel, the covering film comprises a base material, a first rubber material and a second rubber material, the base material is provided with a first part, a second part and a middle part which is arranged between the first and the second parts, and the base material is covered on the edge of the upper surface, a part of the outer surface and the circuit board. The first rubber material is arranged on the first part and is pasted on the edge of the upper surface, the second rubber material is arranged on the second part and is passed on the outer surface, a storage space is arranged on the middle part and the outer surface, and the circuit board is arranged in the storage space.


Common sense and field research have both established that marketing hearing services to physicians costs less than advertising to the general public and can generate as much or more revenue. In one study of hearing-impaired respondents, 63% reported that their best source of information about hearing loss was their primary-care physician and only 16% of patients reported newspaper advertising as an important source.1 Yet, most private practitioners spend tens of thousands of advertising dollars to attract patients to their office, while paying little attention to physician marketing. A key to understanding the importance of physician marketing is recognizing that educating MDs about the consequences of untreated hearing loss and the benefits of hearing healthcare services enables them to make better choices and is likely to result in a higher quality of services to their patients. However, Sergei Kochkin, PhD, summarizes the core challenge facing hearing healthcare practitioners: "Physicians continue to be a barrier to [practice and therefore industry] growth."2 The need to educate physicians is self-evident, based on the following facts: ❖ One leading reason that hearing-impaired consumers give to explain why they have not purchased hearing aids is the opinion of their family doctor, which they said had more influence on their decision not to use hearing aids than the opinions of their: ◆ spouse, friend, or children, respectively; or ◆ a hearing instrument specialist, audiologist, or ENT, respectively.3 ❖ Among hearing-impaired non-owners of hearing aids, nearly half said they had visited their family doctor to discuss their hearing.3 ❖ If people with hearing loss receive a positive recommendation from their physician, they are five times more likely to seek a hearing solution than if the physician gives them a negative recommendation.3 ❖ In calendar year 2004, fewer than 13% of physicians routinely screened for hearing loss during physical exams.4 Furthermore, a National Family Opinion survey conducted for Age Wave Health Services found that among 1084 hearing-impaired participants and 2455 normalhearing people, 63% of the former and 52% of the latter said their best source of information about hearing care was their primary-care doctor.1 Thus, advertising one's practice as an audiologist or hearing instrument specialist may ultimately mean very little to consumers who do not really understand who we are or trust that we can help them. In 1997, an American Academy of Audiology marketing committee, under the direction of Michael Marion, conducted a survey to determine audiologists' current practices, attitudes, and perceptions regarding gaining physician referrals.5 Among the findings were: ❖ "On average, 44% of audiologists' business is generated from physicians' referrals." ❖ "The amount of time spent on marketing activities to obtain more physician referrals doesn't appear to have a direct impact on the volume of business generated from referrals. It is possible, then, that current marketing practices employed by audiologists might not be the most effective choices and could be improved upon." ❖ "Physicians in family practice and ENTs are the most important referral sources for audiologists. Physicians in internal medicine and pediatrics also play a significant role." ❖ "The most frequently employed marketing practices by audiologists to generate physician referrals are by mail (writing letters to physicians and sending information about their practice). Some audiologists also attempt more personal contact by visiting or calling physicians." ❖ "Topping the list of barriers to audiologists seeking physician referrals is lack of time, followed by: (1) an inability to obtain direct contact with physicians, (2) lack of high-quality materials to send or leave behind, and (3) the perception that physicians do not view audiologists as their peers."


Technological advancements allow biometric applications to be more omnipresent than in any other time before. This paper argues that in the current EU data protection regulation, classification applications using biometric data receive less protection compared to biometric recognition. We analyse preconditions in the regulatory language and explore how this has the potential to be the source of unique privacy risks for processing operations classifying individuals based on soft traits like emotions. This can have high impact on personal freedoms and human rights and, therefore, should be subject to data protection impact assessment.


Economic theory suggests that agents care for the outcomes they produce. This paper studies the conditions under which a pro-social mission of a job affects workers motivation to perform well. In particular, we investigate whether it makes a difference if workers actively decide upon doing a mission-oriented job or are exogenously assigned. We find that a pro-social mission itself affects only a small group of workers in a positive way whereas self-selection into a mission-oriented job leads to a highly significant overall performance boost.


This paper intends to inspect Mun-jang and its traditional implications and reasons. 1930s 'Crisis of modernity', 'The Transcendence of the modern' discourse makes the value of historical context or traditional thing upgrading. Mun-jang is located in the center of the contemporary context, 'Korean' and 'traditional', 'classic'. This paper approaches the discourse of Mun-jang by examining in detail whether Mun-jang has been defined as the ideology of 'traditionalism'. Rather than the pre-determined value of the screening, a subject of traditional is a matter of choice that requires the active involvement in that matter. Within the traditional screening process and reflect on the past, there is the reasons and thought on the present worrying that the subjectivity of the modern and the attention are involved. At this time members of the Mun-jang showed subjective insights of the individual attention and they were the most meaningful thing in Mun-jang. Lee Byung-gi, Jeong Ji-yong, Lee Tae-joon and Kim Yong Joon is clearly apparent at the creative arts in Mun-jang. They have in common in aspects such as language or material. Their thoughts were very simmilar and it can be called 'seogwongi' and 'munjahyang'. They are summarized as the work of art is a projection of an individual's unique personality. Subjective perception of the gaze is very important in the traditional way of thinking and the literary tradition of a literary artist with the ideas and ideals they were expressing. Therefore, in the literary artist works, the most important issue is to symbolize the spirit world not the shape of things. This paper revealed the members of Mun-jang quoted and imitated Chusa, literary artist directly. Their traditionalism is in the various possibilities of the traditional way of thinking rather than an issue of material. At that time this way of poetic thought and reason is aganst the authority of outside and is represented as his own part which is not suppressed and active intellectual and emotional potential. It was a way to express and to secure the self's world. Therefore, their traditional way of thinking, 'seogwongi' and 'munjahyang' was the way of presenting the self independent from colonial traditionalism and the discrimination by Japanese imperialists.


Frequent occurrence of economic behavior about disposal of forest resources assets,transfer,mortgage loan and so on,with the deepening of the reform of collective forest property right system.In order to explore the theory and practice of forest resources.By taking the Golden Forest Farm as the research object,combined with the theory of asset appraisal to evaluation forest resources on Golden Forest Farm.


The signs and symptoms of myofibrillar myopathy vary widely among affected individuals, typically depending on the condition's genetic cause. Most people with this disorder begin to develop muscle weakness (myopathy) in mid-adulthood. However, features of this condition can appear anytime between infancy and late adulthood. Muscle weakness most often begins in the hands and feet (distal muscles), but some people first experience weakness in the muscles near the center of the body (proximal muscles). Other affected individuals develop muscle weakness throughout their body. Facial muscle weakness can cause swallowing and speech difficulties. Muscle weakness worsens over time.


Study on the relationship between FDI and export trade has developed from qualitative to quantitative analysis, but most studies are concentrated on the cause and result relation between them. Based on the data from 1983 to 2002, this paper studies the relationship between FDI and China's export scale, export competitiveness and export structure.


Traditional piston wobble-plate engine can not solve essentially the problem of excessive vibration noise due to the complicacy of force and restrain condition in the join with wobble-plate.To reduce the noise of torpedo engine,a new type of plunger piston wobble-plate engine is proposed in this paper.The structure and principle of the engine are intro-duced.The mechanical characteristics and the movement rule of plunger piston with cylinder and wobble-plate are ana-lyzed.The force balance equation is built based on the piston force analysis,and the relationship formula between the minimum length inside the cylinder and the whole length of the piston is derived.The conclusion may provide a theoreti-cal evidence for the design of plunger piston wobble-plate engine.There is no restraining mechanism on the wobble-plate.The autorotation of the plunger piston during working process can improve lubrication,and reduce friction and noise.


Cholesterol-Protein Interaction: Methods and Cholesterol Reporter Molecules.- Cholesterol in Alzheimer's Disease and other Amyloidogenic Disorders.- Cholesterol-Binding Viral Proteins in Virus Entry and Morphogenesis.- Sterol-Protein Interactions in Cholesterol and Bile Acid Synthesis.- Cholesterol Oxidase: Structure and Function.- Oxysterol-Binding Proteins.- High Density Lipoprotein Structure-Function and Role in Reverse Cholesterol Transport.- Lipoprotein Modification and Macrophage Uptake: Role of Pathologic Cholesterol Transport in Atherogenesis.- Cholesterol Interaction with Proteins That Partition into Membrane Domains: An Overview.- Caveolin, Sterol Carrier Protein-2, Membrane Cholesterol-Rich Microdomains and Intracellular Cholesterol Trafficking.- Cholesterol in Niemann-Pick Type C disease.- Protein Mediators of Sterol Transport Across Intestinal Brush Border Membrane.- Cholesterol at the Endoplasmic Reticulum: Roles of the Sigma-1 Receptor Chaperone and Implications thereof in Human Diseases.- Prominin-1: A Distinct Cholesterol-Binding Membrane Protein and the Organisation of the Apical Plasma Membrane of Epithelial Cells.- Mammalian StAR-Related Lipid Transfer (START) Domains with Specificity for Cholesterol: Structural Conservation and Mechanism of Reversible Binding.- Membrane Cholesterol in the Function and Organization of G-Protein Coupled Receptors.- Cholesterol Effects on Nicotinic Acetylcholine Receptor: Cellular Aspects.- Cholesterol and Myelin Biogenesis.- Cholesterol and Ion Channels.- The Cholesterol-Dependent Cytolysin Family of Gram-Positive Bacterial Toxins.- Cholesterol Specificity of Some Heptameric ?-Barrel Pore-Forming Bacterial Toxins: Structural and Functional Aspects.- Cholesterol-Binding Toxins and Anti-cholesterol Antibodies as Structural Probes for Cholesterol Localization.


This paper points out several common psychological problems of editors of medical journals,analyzes the reasons for these problems,and puts forward some concrete countermeasures and suggestions.


The article by Nijhawan et al. 1 in this issue of the Journal of Women's Health evaluated the important aspect of identifying preventive healthcare needs of incarcerated women. Unequal access to healthcare unfortunately continues to plague our nation's prison population, currently totaling almost 2 million people. The overall incarceration rates of state and federal prisoners continue to rise; at midyear 2007, 509 of 100,000 U.S. residents were incarcerated, up from 480 of 100,000 at end of year 2003. By the end of year 2007, the number of female inmates has continued to rise since the end of year 2000 at a greater rate (3.2%) compared to male inmates (2%). Although women account for approximately 7% of the total inmate population in state and federal prisons, female incarceration rates reveal racial and ethnic differences similar to those of male inmates. Black women (with a prison and jail rate of 348 per 100,000) were nearly two and a half times more likely than Hispanic women (146 per 100,000) and over 4.5 times more likely than white women (95 per 100,000) to be incarcerated in midyear 2007. Not only do the majority of these inmates carry a racial disparity, but they also carry considerable disparity in the burden of disease within the correctional system as well as in the community upon release. Prevalence rates within the correctional setting of mental illnesses are 30%–50% compared with 11% in the general population, and alcohol and drug problems occur in 30%–70% of the incarcerated population compared with 3%–6% in the general population. Furthermore, certain communicable infectious diseases occur at higher rates in the incarcerated population than in the community. HIV=AIDS is three to four times greater; tuberculosis (TB) occurs in 40% of incarcerated populations, and chronic hepatitis C viral (HCV) infection occurs in almost 50%. In the article by Nijhawan et al., of the 70% incarcerated women who reported being tested for HCV, almost 40% reported testing positive, which is 20 times greater than in the general population (1.6%). The authors do not state in the article if the HCV-positive inmates received treatment or evaluation for treatment for chronic HCV infection; however, it is unlikely given previous low reports of HCV treatment in correctional settings. Previous studies have demonstrated that prisoners adhere to antiretroviral therapy regardless of the antiretroviral regimen, causing the majority to have undetectable HIV viral loads. Extrapolating from these results, it would be expected that HCV treatment adherence rates with weekly injections of pegylated interferon and daily oral ribavirin would likely be high within incarcerated populations. Future work should be done to begin the evaluation process of detecting chronic HCV infection (i.e., checking HCV viral load and HCV genotype, imaging of the liver, liver biopsy) and initiating treatment for all inmates who meet the criteria and then developing linkages with HCV treatment providers in the community upon release. Although women comprise only 7% of the incarcerated population in the country,3a they have a higher prevalence of HIV and other sexually transmitted diseases (STDS) than male prisoners. In terms of HIV, the Centers for Disease Control and Prevention (CDC) now reports that heterosexual contact is the most common mode of acquiring HIV in women (83%), and most women tend to be incarcerated for drugrelated and sex work crimes that put them at risk for acquiring HIV and other STDs. Most prisoners have a high degree of other STDs besides HIV upon entrance to correctional facilities, including gonorrhea, syphilis, and Chlamydia infection. Furthermore, cervical cancer most commonly caused by another STD, human papillomavirus (HPV), is more prevalent within the incarcerated population. As highlighted in Nijhwan et al.'s article, known preventive screening Pap smears were reported in only 62% of the studied population, and of that screened population, 40% reported an abnormal Pap smear, which is six times greater than that reported in the general community. Routine preventive age-appropriate cancer screening should be offered to all inmates in order to detect and treat cancers earlier to prevent unnecessary deaths. An estimated seven to eight million prison and jail inmates are released to the community every year, often for a sentence of less than 2 years. It is known that upon release to the community, HIV-infected prisoners do not pick up their antiretroviral prescriptions and, therefore, are nonadherent and develop higher HIV-1 viral loads, thus becoming more infectious to noninfected persons. It is also known that prisoners, unfortunately, return to high-risk behaviors upon release to the community, such as shared needles and unprotected sex, that subsequently lead to greater transmission and acquisition of communicable blood-borne infectious diseases, such as HIV and HCV. All correctional facilities should offer mandatory HIV testing as recommended by the CDC in 2006 and counseling to prevent future acquisition and transfer of STDs within the community. Given the


Artificial neural network (ANN) is a significant tool for classification of various types of disease using either Biosignals/images or may be any kind of physical parameters. Establishment of appropriate combination of learning, transfer function and training function is a very tedious task. Here, we compared the performance of different training parameters in feed forward neural network for differentiating of Parkinson's disease using human brain (Electroencephalogram) and muscle signals (Electromyogram) features as the input vector. 3 different types of training algorithm with six training functions is used. They are Gradient Descent algorithms (traingd, traingdm), Conjugate Gradient algorithms (trainscg, traincgp) and Quasi-Newton algorithms (trainbfg, trainlm). Proposed work compared the mentioned algorithm in terms of mean square error, classification rate (%),R-value and the elapsed time. Study showed that trainlm (Levenberg-Marquardt) best fits for larger data set. It showed the highest accuracy rate of 100% with 0 mismatch classification with a best validation mean square error of 0.0040254 in 3 epochs with a elapsed time of 1.12 seconds. The R-value found was 0.9998 which is in nearly equals to 1. Hence, Levenberg-Marquardt can be used as a training function for the classification of any brain disorder


Studies Cited in This Issue ● ''The Economic Burden of Physical Inactivity in Canada,'' by Katzmarzyk, Gledhill, and Shephard, published in CMAJ. ● ''Effects of Physical Activity Counseling in Primary Care,'' by the Writing Group for the Activity Counseling Trial Research Group, published in JAMA. ● ''Association Between Cigarette Smoking and Anxiety Disorders During Adolescence and Early Adulthood,'' by Johnson, Cohen, Pine, Klein, Kasen, and Brook, published in JAMA. ● ''Improved Smoking Cessation in Smokers Given Ultrasound Photographs of Their Own Atherosclerotic Plaques,'' by Bovet, Perret, Cornuz, Quilindo, and Paccaud, published in Prev Med.


The use of sound is essential to the survival of cetaceans. Therefore, anthropogenic sound exposure is a concern. Cetaceans can change the amplitude, duration, repetition rate, and/or frequency of sounds they produce to compensate for masking noise. Potential costs of such compensation are unknown, and no empirical data on the metabolic cost of sound production in marine mammals exist. This study aims to determine the metabolic cost of cetacean vocalizations to assess the biological significance of vocal compensation. Oxygen consumption, respiration rates, and vocalizations of two captive bottlenose dolphins were recorded during sound production at moderate levels. One dolphin produced his signature whistle while the other produced a pulsed squawk or squeaklike sound. Both types of vocalizations increased oxygen consumption while respiration rates did not change. This increased oxygen consumption is likely due to increased metabolic demand related to sound production, rather than changes in breathing patt...


Agriculture industrialization is an innovation on management institution in our rural area,and it is also the basic developmental direction of agriculture and the only way to realize modern agriculture."Developing Agriculture on Orders" is the basic organizing form of agriculture industrialization and deserves to be spread.It is quite common that relationships between companies and farmers are loose and the rate of breaching contract is very high.So it is necessary and important to study on ways to avoid them.


The paper describes the design of the synchronous reluctance motor of the IE5 energy-efficiency class with fractional winding (2.5 slots per pole and phase) for fan applications. The optimization is done with the Nelder-Mead method. The objective function is constructed of the following parameters: the averaged efficiency over the motor modes of the fan profile (the torque is proportional to the speed squared), the converter power, the torque ripple and the voltage total harmonic distortion at sinusoidal current. The motor efficiency is much higher than the IE5 class requirement and remains high in the wide range of powers at the fan load profile. Also, the motor has low torque ripple despite that its rotor and stator have no skewing.


Among the lost manuscripts of the Library of the Palau Reial Menor in Barcelona, there was a volume containing the Catalan translation of Matfre Ermengaud's Breviari d'amor and Anselm Turmeda's Llibre dels bons amonestaments. Although this manuscript cannot be currently examined, two secondary sources remain. The aim of this paper is to offer the palaeographic transcription and the editionof Emengaut's fragment, accompanied by a comparative study regarding the other manuscripts of the Catalan tradition. The Palau witnes manuscript is essential to understand the diffusion of this encyclopaedic work as it is the earliest dated Breviari. - Keywords Matfre Ermengaut; Breviari d'amor; Anselm Turmeda; Library of the Palau Reial Menor; Manuscripts; Medieval Catalan Translations.


The objective of this prospective study is to learn the value of fine needle biopsy (FNB) in the diagnosis of tuberculous cervical lymphadenitis. Twenty two patients with chronic cervical lymphadenitis were diagnosed by fine needle biopsy and open biopsy performed there after on the same node. The results of the cytologic and histopathologic diagnoses were analyzed. The histopathology is used as the final confirmation and considered as gold standard of the diagnosis. FNB cytology revealed a sensitivity 86.7%, specificity 71.4%, positive predictive value 86.7%, negative predictive value and accuracy of 71.4%, and 81.82%, consecutively. Chi-square analysis (a =0.05) showed that there was no significant difference between FNB cytology and histopathological examination (p= 0.003216). It can therefore be concluded that FNB is a reliable diagnostic tool in the management to avert the more invasive surgical procedures undertaken in the diagnosis of tuberculous lymphadenitis.


Background:  Activation of cell‐mediated immunity by soluble interleukin‐2 receptor alpha (sIL‐2Rα) release is well documented. The aim of this study was to measure serum concentrations of sIL‐2Rα in patients with autoimmune and non‐autoimmune thyroid disorders in different stages of thyroid function, before and after administration of l‐thyroxine (l‐T4) and its discontinuation as well as before and during methimazole administration.


(NRRI) with funding provided by participating member commissions of the National Association of Regulatory Utility Commissioners (NARUC). The views and opinions of the authors do not necessarily state or reflect the views, opinions, or policies of the NRRI, the NARUC, or NARUC member commissions. EXECUTIVE SUMMARY Public utility commissions (PUCs) are increasingly adopting, or considering the adoption of, integrated resource planning (IRP) for local gas distribution companies (LDCs). The Energy Policy Act of 1992 (EPAct) requires PUCs to consider IRP for gas LDCs. This study has two major objectives: (1) help PUCs develop appropriate regulatory approaches with regard to IRP for gas LDCs; and (2) help PUCs respond to the EP Act directive. IRP requires a regulated utility to give equal consideration to both supply side and demand-side management (DSM) options in planning a resource mix. IRP has been extensively used as a policy tool to regulate electric utilities; it is a relatively new regulatory approach for gas LDCs. The rapidly developing competition in the energy industry warrants a reexamination of underlying issues and policy goals of IRP. Some of these issues include the nexus between competition and the participatory approach germane to the IRP process, the traditional regulatory issues of cost minimization and ratepayer equity, and the effectiveness of PUC regulation to achieve IRP goals of energy efficiency and environmental protection. The study finds that it is appropriate for PUCs to pursue energy efficiency within the traditional regulatory framework of minimizing private costs of energy production and delivery. The study concludes that PUCs should playa limited role in addressing environmental externalities. The study finds that in promoting energy efficiency, PUCs should pursue policies that are incentive-based, procompetitive, and sensitive to rate impacts. The study evaluates a number of traditional ratemaking mechanisms, in addition to nontraditional mechanisms, on the basis of cost minimization, energy efficiency, competitiveness, and other criteria. The mechanisms evaluated include direct recovery of DSM expenses, lost revenue adjustments for DSM options, revenue decoupling mechanisms, sharing of DSM cost savings, performance-based rate of return for DSM, provision of DSM as a separate service, deregulation of DSM service, price caps, and deregulation of the noncore gas III market. The study concludes with general recommendations for regulatory approaches and ratemaking mechanisms that PUCs may wish to consider in advancing IRP objectives.


Kulkarni, Y. 2020. Computational Modeling of the Structure, Function and Dynamics of Biomolecular Systems. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1885. 72 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0828-9. Proteins are a structurally diverse and functionally versatile class of biomolecules. They perform a variety of life-sustaining biological processes with utmost efficiency. A profound understanding of protein function requires knowledge of its structure. Experimentally determined protein structures can serve as a starting point for computer simulations in order to study their dynamic behavior at a molecular level. In this thesis, computational methods have been used to understand structure-function relationships in two classes of proteins intrinsically disordered proteins (IDP) and enzymes. Misfolding and subsequent aggregation of the amyloid beta (Aβ) peptide, an IDP, is associated with the progression of Alzheimer's disease. Besides enriching our understanding of structural dynamics, computational studies on a medically relevant IDP such as Aβ can potentially guide therapeutic development. In the present work, binding interactions of the monomeric form of this peptide with biologically relevant molecular species such as divalent metal ions (Zn, Cu, Mn) and amphiphilic surfactants were characterized using long timescale molecular dynamics (MD) simulations. Among the metal ions, while Zn and Cu maintained coordination to a well-defined binding site in Aβ, Mn-binding was observed to be comparatively weak and transient. Surfactants with charged headgroups displayed strong binding interaction with Aβ. Complemented by biophysical experiments, these studies provided a multifaceted perspective of Aβ interactions with the partner molecules. Triosephosphate isomerase (TIM), a highly evolved and catalytically proficient enzyme, was studied using empirical valence bond (EVB) calculations to obtain deeper insights into the catalytic reaction mechanism. Multiple structural features of TIM such as the flexible loop and preorganized active site residues were investigated for their role in enzyme catalysis. The effect of substrate binding was also studied using truncated substrates. Finally, using enhanced sampling methods, dynamic behavior of the catalytically important loop 6 was characterized. The importance of structural stability and flexibility on protein function was illustrated by the work presented in this thesis, thus furthering our scientific understanding of proteins at a molecular level.


Diabetic macular edema (DME) is the most common retinopathy that seriously threatens the visual function of diabetic patients, and it represents a major cause of blindness especially among people in working age. Ocular VEGF inhibitors are most often used as a first line therapy for DME, and have revolutionary significance in improving visual outcomes. However, there remain 30%-50% patients who fail to respond to anti-VEGF treatment, and the need for frequent injections brings a substantial treatment burden to patients and society. Novel therapeutic strategies include improving efficacy and duration of anti-VEGF drugs, targeting inflammation, the plasma kallikrein-kinin system, the angiopoietin-Tie2 system, neurodegeneration and other alternative pathways, as well as using subthreshold and targeted laser therapy. It is still challenging in the individualized management of DME to identify non-responders to anti-VEGF drugs and to establish a standardized regimen for the switch from anti-VEGF therapy to anti-inflammatory or other alternative treatment. Further research and development of new therapies, as well as preventive and screening strategies, are needed to reduce the impact of diabetic retinopathy and DME on public health.

Key words:
Macular edema/therapy; Diabetic retinopathy/complications; Editorial


In intramedullary tibial nailing, multi-planar locking makes stabilization of proximal and distal metaphyseal fractures possible. A known complication in intramedullary nailing of the tibia is iatrogenic injury to neuro-vascular structures caused by the insertion of locking screws. As shown in previous studies, the distal positioning of the nail is important, as it determines the course of the locking bolts. The goal of the present study was to display the consequences of posterior nail malpositioning with respect to the safety of the distal medio-lateral locking screws and the available options. Human cadaveric legs were plastinated according to the sequential plastination technique after intramedullary nailing of the tibia and were then cut transversely. The tibial nails were placed centrally or posteriorly. Macroscopic analysis showed a distinct drawback of posterior nail positioning, with diminished options for the placement of the locking screws and thereby a risk of damaging the anterior and posterior neuro-vascular bundles by distal medio-lateral locking screws.


This paper documents the shift toward increasingly coercive means of collecting debt from working class and poor borrowers, with a specific focus on incarceration. Placing this trend within an historical trajectory, it is argued that the law has always been central to creating and securing the social relations of debt as class relations. While the abolition of debtors' prisons in the 19th century helped to shift struggles between debtors and creditors out of public view and into the depoliticized realm of 'the law', a number of factors have led to its reappearance in the contemporary era. These include (1) changes to bankruptcy legislation that have given creditors greater power over debtors, (2) the emergence of the debt-buying industry and (3) the growing privatization, decentralization and commercialization of the state, which have transformed it into a creditor that relies on its power to punish to compel payment from some of the poorest debtors.


No one set of evaluation criteria exists to evaluate all research data, with both quantitative and qualitative researchers utilising estimations of rigour from within their respective paradigms. Where multiple methodologies are brought to bear upon a specific research topic, data and methods are often triangulated. This term, triangulation, describes the use of a variety of data sources or methods to examine a defined phenomenon either simultaneously or sequentially in order to produce a more accurate account of the phenomenon under investigation. Thus the main aim of data, investigator or methodological triangulation is to gain a richer and more illuminating interpretation of the subject under scrutiny. Many writers, however, question whether the quality of outcomes are actually improved by integrating methods. Potter and Wetherell (1987), for example, argued that, rather than homing in on a phenomenon, triangulated research findings 'home out' in all manner of directions. Further, Alvesson and Skoldberg suggest that 'Different methods capture different kinds of aspects, making it difficult on the basis of their combination to reach a coherent result' (2000: 47). The authors of this paper appear to concur with this, indicating in their comprehensive review of the literature that, where methodological integration is applied in research, the process is not always well explicated, even in those studies that demonstrate added value in terms of outcomes. It is fair to say that the specific criteria for assessing the findings of integrative research are difficult to pin down; other than applying the already existing measures to parts of the data, how does one evaluated the whole of the study, its coherence and seamlessness? In other words, there


Abstract Biluribin is a degradation product of haemoglobin that reaches the liver in its unconjugated form tightly bound to albumin and so is not excreted into urine. In the liver, it is taken up by active transport and conjugated within the hepatocytes to form bilirubin monoglucuronides and diglucuronides. These are water soluble, are excreted into bile and are further metabolized by gut bacteria into urobilinogen (partly reabsorbed into an enterohepatic circulation) and the various stercobilins that produce the brown pigmentation of stool. An understanding of bilirubin metabolism is central to the approach to jaundice. Jaundice is best subdivided into unconjugated and conjugated types. Routine chemical methods of differentiating unconjugated (indirect) bilirubin from conjugated (direct) bilirubin are unreliable; it is preferable to depend on the presence of bile in urine as evidence of conjugated jaundice. The disappearance of urobilinogen from urine in conjugated jaundice (e.g. extrahepatic obstruction) or its appearance in excess in unconjugated jaundice demonstrates the pathophysiology but is seldom of value in clinical practice. Dipsticks for urinary urobilinogen are unreliable. Jaundice becomes clinically apparent when plasma concentrations are 2–3 times normal. In unconjugated jaundice in adults, plasma bilirubin of more than 100 μmol/litre is uncommon (normal


Epidemic results show that cigarette smoker has decreased risk of developing Parkinson's disease (PD) and Alzheimer's disease (AD) although the mechanism has not been identified. Current study found that: (1) Nicotine scavenged hydroxyl and superoxide free radical and inhibit oxidation of 6-OHDA. (2) Nicotine inhibited the oxidation of 6-OHDA and N-methyl-4-phenylpyridine (MPP +) induced mitochondria high-amplitude swelling and cytochrome C released from intact mitochondria. (3) Nicotine protected cultured hippocampal neurons against A(βinduced apoptosis. (4) Nicotine prevented Aβ and copper deposition in the brain of transgenic APP V7171 mouse. These results are of great importance in explaining the preventive effects of nicotine against cell apoptosis in neurodegenerative diseases.


The incidence of self-medication among the population of Novgorod region has been investigated. 100 persons have been offered to answer a questionnaire. 69% of the population are engaged in self-medication. It is necessary to inform persons when providing them with over-the-counter drugs, to warn against the unjustified using of remedies, to increase the efficacy of self-medication.


Ordered self-assembly of nanocrystals is scientifically interesting due to not only the unique properties of the nanocrystals, but also the collective properties of the assembly. Compared to lithography method, self-assembly is limited by a lack of control over the sizes of the ordered arrays, resulting in difficulties in characterizing their physical and chemical properties. New techniques are needed to manipulate the self-assembling process and the nanostructures formed. In this work, polystyrene (PS) spheres were used as the template to form large bulk ordered anatase nanostructure with cobalt doping. The ordered PS template was infiltrated with absolute alcohol solution of titanium butoxide. After the precursor was dried, it was treated at 160°C for 5 hours and then at 450°C for another 5 hours. To dope cobalt into the structure, the porous titania host was immersed in a heptane solution with cobalt carbonyl. After drying in vacuum at room temperature, it was treated at 160°C.


555 Background: Percutaneous ablation of neoplastic tissue by radiofrequency ablation (RFA), microwave ablation (MWA) or brachytherapy is considered a potentially curative treatment for early HCC, but recurrence rates are high. Local ablative therapies release immunogenic stimuli that can trigger an anti-tumoral immune response, which is, however, dampened by counter-regulatory mechanisms mediated through immune checkpoints, such as CTLA-4 and PD-1. Combining local therapies with immunotherapies may shift the balance to a more robust immunostimulatory response. We therefore hypothesized that peri-interventional treatment with pembrolizumab may synergize with and improve outcome of local ablative therapy. Methods: This single arm phase II trial investigates peri-interventional treatment with pembrolizumab combined with RFA/MWA or brachytherapy, or - as recommended for tumors larger than 3 cm – combined with TACE and RFA/MWA or brachytherapy in early-stage HCC with maintained liver function (Child Pugh A) who did not receive prior local or systemic therapy. Pembrolizumab (200mg, q3w) was administered intravenously for 2 cycles, followed by radiologic imaging and local therapy. Pembrolizumab was continued for up to 12 months. The primary efficacy endpoint was defined as overall response rate (ORR, RECIST 1.1) after 2 cycles of pembrolizumab and before local therapy while secondary endpoints are time to recurrence (TTR, defined as the length of time after performance of local ablation resulting in confirmed absence of viable tumor tissue until documented tumor recurrence), recurrence free survival and overall survival (OS) along with safety and tolerability. Results: 30 patients (pts, ECOG 0 or 1) were enrolled in 9 centers in Germany, with a median age of 70 years and a predominance of male pts (73.3%). All pts received at least 1 dose of study treatment and the median number of cycles was 13. ORR was 13.3%, with 6.7% complete responses (CR) and 6.7% partial responses (PR) after two cycles of pembrolizumab and before local ablation. Subsequent local ablation was performed in 25/30 pts. With ongoing follow-up median of 14 months (Sep 2022), provisional median overall survival time (mOS) was not reached and provisional median time to recurrence (TTR) was 17.41 months. No new safety signs were observed. Conclusions: The study did not meet its primary endpoint. The hypothesized ORR of 30% before local therapy was not reached. However, there is evidence for the efficacy of peri-interventional treatment with pembrolizumab combined with local ablative therapy without new safety signals. Our findings support further evaluation of this combination treatment in early-stage HCC. Clinical trial information: NCT03753659 .


Electronic stability control (ESC) system is well known as a method to assist the driver in recovering from unintended situations, such as understeering and oversteering behaviors. One of issues of this ESC is precise distribution of the brake force for generation of the vehicle yaw moment. In this paper, a new design of ESC systems is proposed. First, the model based controller with vehicle bicycle model computes the correction yaw moment, which makes the vehicle follow the desired yaw rate. Then, weighted least squares (WLS) allocation method minimizing the user-defined cost function with equality constraints is implemented for generation of the brake pressures of individual wheels. In addition, taking both weight shifting caused by pitching motion of the vehicle body and minimum disturbance of longitudinal dynamics into account, the limits of brake pressures are managed in real time. The performances of the proposed algorithm are verified in the simulation environments using Carsim and Matlab/Simulink.


Yangshan ultra-large gold deposit is the first discoveried deposit of more than 300 tons of gold resource in China and even whole Asia.The relationship of the deposit and the granites in orefield is very close.We discuss the characters of plagioclase granite porphyry and granite aplite esposed in Yangshan area from the start of geochemistry characters of granites in Yangshan deposit.Yangshan granites belongs to calc-alkali magma series and superperaluminous.The higher differentiation index(71.12~87.0) indicates the intense differentiation of origin magma.The partion chart of rare earth elements is right deviation,lower ∑REE(32.18×10-6~100.21×10-6),the major of LREE/HREE upwards seven.High field strong elements(Nb、Ta、Zr)are negative anomaly and Rb/Sr is 0.38~2.08.From the discrimination diagrams for the tectonic settings of granites,Yangshan granites comed from the settings of post collision.There are no clearly different except for the intruding time between two types of granites,and they resulted from a homgenous magma synthesized the revolutional history of district geology and age of granites from earlier studies,we conclued that the Yangshan ultra-large gold deposit formed during the post-collision extension between the North China block and the Yangtze block.


A compact linac system is designed using a longer accelerating column in a C-band linac. It reduces the total number of RF units for the given linac beam energy and results in the cost-effective use of RF powers. For the 10 GeV PAL-XFEL project, a C-band accelerating column of 2.2-m long is investigated, which is 22% longer than 1.8-m for the SACLA at SPring-8. The detailed RF and thermal characteristics are presented by an analytic model.


The conditions under which Compressed sensing (CS) succeeds depend on the structure of the measurement matrix. Researches indicated that matrices whose entries are drawn independently from certain probability distributions satisfy the restricted isometry property (RIP) and guarantee exact recovery of a sparse signal with high probability. Motivated by signal processing applications, random filtering with Toeplitz sensing matrices whose elements are drawn from the same distributions were considered and shown to also be sufficient to recover a sparse signal from reduced samples exactly with high probability. In order to achieve reduction of sampling rate in impulse radio Ultra-Wideband (IR-UWB) communication systems, the output streams of UWB channel were periodically down-sampled. Sub-sampling at the receiver leads to quasi-Toeplitz-structured measurement matrices, whose entries are UWB channel coefficients. In this paper, the feasibility of this kind of quasi-Toeplitz matrices as measurement matrices is discussed. It is shown that the quasi-Toeplitz matrices with entries drawn from logarithm normal distribution satisfy RIP with high probability and also ensures the exact reconstruction of the sparse signals. Simulation results validate their performance.


Two distinct types of ferritin-like molecules often coexist in bacteria, the heme binding bacterioferritins (Bfr) and the non-heme binding bacterial ferritins (Ftn). The early isolation of a ferritin-like molecule from P. aeruginosa suggested the possibility of a bacterioferritin assembled from two different subunits [Moore, G. R., Kadir, F. H., Al-Massad, F. K., Le Brun, N. E., Thomson, A. J., Greenwood, C., Keen, J. N. and Findlay, J. B. C. (1994) Biochem. J. 304, 493– 497]. Subsequent studies demonstrated the presence of two genes coding for ferritin-like molecules in P. aeruginosa, designated bfrA and bfrB, and suggested that two distinct bacterioferritins may coexist [Ma, J.-F., Ochsner, U. A., Klotz, M. G, Nanayakkara, V. K., Howell, M. L., Johnson, Z., Posey, J. E., Vasil, M. L., Monaco, J. J., and Hassett, D. J. (1999) J. Bacteriol. 181, 3730–3742]. In this report we present structural evidence demonstrating that the product of the bfrA gene is a ferritin-like molecule not capable of binding heme which harbors a catalytically active ferroxidase center with structural properties similar to those characteristic of bacterial and archaeal Ftns and clearly distinct from the ferroxidase center typical of Bfrs. Consequently, the product of the bfrA gene in P. aeruginosa is a bacterial ferritin, which we propose should be termed Pa FtnA. These results, together with the previous characterization of the product of the bfrB gene as a genuine bacterioferritin (Pa BfrB) [Weeratunga, S. J., Lovell, S., Yao, H., Battaile, K. P., Fischer, C. J., Gee, C. E., and Rivera, M. (2010) Biochemistry 49. 1160– 1175] indicate the coexistence of a bacterial ferritin (Pa FtnA) and a bacterioferritin (Pa BfrB) in P. aeruginosa. In agreement with this idea, we also obtained evidence demonstrating that release †This work was supported by grants from the National Science Foundation (MCB-0818488), the National Institute of Health, GM-50503 and P20 RR-17708 from the National Center for Research Resources. €Coordinates and crystallographic structure factors for the distinct Pa FtnA structures have been deposited in the protein data bank under accession codes 3R2O (as isolated pH 6.0), 3R2K (as isolated pH 7.5), 3R2H (as isolated pH 10.5), 3R2R (Fe soaked, pH 6.0), 3R2L (Fe soaked, pH 7.5), 3R2S (double soaked, pH 6.0) and 3R2M (double soaked, pH 7.5). *Corresponding author: Mario Rivera, Ralph N. Adams Institute for Bioanalytical Chemistry & Department of Chemistry, University of Kansas, Multidisciplinary Research Building, 2030 Becker Dr., Lawrence, KS 66047. Telephone: 785-864-4936; Fax: 785-864-1916; firstname.lastname@example.com. SUPPORTING INFORMATION Amino acid sequence of the protein coded by the P. aeruginosa bfrA gene (Pa FtnA) aligned against the amino acid sequences of bacterioferritins of known structure; 2Fo-Fc electron density maps of the ferroxidase center ligands of Pa FtnA Fe soaked and double soaked; conformational changes in the Pa FtnA ferroxidase center upon binding iron; anomalous difference map showing sulfate in a 3-fold pore. This material is available free of charge via the Internet at http://pubs.acs.org NIH Public Access


This study was carried out in Qimbaba forest, northwest of Ethiopia to determine woody species diversity, regeneration capacity and soil seed bank in Eucalyptus plantation forest and adjacent natural forest. A total of 40 circular sample plots of 314 m 2 were established along a transect line at every 200 m between them. Transects were laid in east–west directions at 200 m distance from each other. Soil seed bank analysis was done from soil samples collected in each of the 40 plots (160 samples) to examine the similarity between the soil seed flora and aboveground vegetation. A total of 71 woody plant species (33 in Eucalyptus Plantation) and (63 in Natural Forest) were determined with the density ranging between 404 to 635 per ha in the plantation and natural forest, respectively. The population structure showed an inverted J-shape in both forests. The basal area were 4.9 m 2 /ha and 24.5 m 2 /ha for plantation and the adjacent natural forest respectively. The regeneration status in the Eucalyptus plantation was 699 seedlings and 344 saplings/ha while the natural forest had 1117 seedlings and 390 saplings/ha. On the other hand, the species richness of regenerated trees in the plantation and natural forest were 21 and 38, respectively. A total of 14 plant species representing 11 families were recovered from the soil seed bank, 12 (in 10 families) species in the natural forest and 7 of them were in the eucalyptus plantation forest (5 families). Soil seed bank (SSB) was not similar in the two forests with Sorenson's similarity values of 0.208. There were 11,022 seeds/m 2 (natural forest) and 10,667 seeds/m 2 (Eucalyptus plantation forest) in the SSB. Keywords: Florstic diversity, Eucalyptus, Natural forest, Soil seed bank, Fostering effect


This retrospective study investigated the data of 427 patients who had suffered from orofacial pain and were referred to Shiraz oral medicine department, Shiraz, Iran. The patients' diagnoses, gender, age, treatment, response to treatment, pain duration, severity of pain and other items were extracted from the medical records in the past 10 years. Most of the patients were females and their mean age was 49.57. The main diagnoses were temporomandibular disease (43.9%) and neuralgic pains (27.8%). Most of the patients had suffered for more than 6 months from the pain onset. 47.2% showed remission or significant improvement and 27% did not respond to treatment. 55.5% of the patients had experienced a severe pain. In this population, a majority of the patients had suffered from temporomandibular disease and neuralgia. The chronic pain was reported to be higher in middle aged females which means that age and gender can be considered as two risk factors. Keyword: Orofacial pain, Epidemiology, Chronic pain, Dental patients, Clinical observation, Anesthesiology O R G IN A L A R T IC L E P I: S 2 3 2 2 -4 7 8 9 1 7 0 0 0 0 1 -7 R eeiv ed 0 7 F eb . 2 0 1 7 A ccep ed 0 5 M r. 2 0 1 7


Objective To discuss the value of bilirubin in urine to predict intrahepatic cholestasis of pregnancy.Methods To test bilirubin in urine and serum total bile acid of 133 pregnant women who are clinically suspected with ICP in out patient of our hospital from January to June in 2008.As the results of serum total bile acid as a gold standard,we evaluate the consistency of the two detection methods.Results The pregnant women with positive results of bilirubin in urine are with high level of serum total bile acids,the two methods have the consistency.Conclusion Urinates the bilirubin examination is convenient in out patient,with high specificity,can be used to predict ICP.


The copper chelate-catalyzed decomposition of o-methoxycarbonyl-α-diazoacetophenone was carried out in benzene. The reaction gave a dimer of a carbonyl ylide intermediate. The intermediate was trapped with dipolarophiles such as trans-dibenzoylethylene, ethyl fumarate, isoprene and dimethyl acetylenedicarboxylate, yielding 1,3-dipolar adducts in a stereospecific and stereoselective manner. Similar results were obtained in the catalytic decomposition of o-(n-butoxycarbonyl)-α-diazoacetophenone. The configuration of adducts and the mechanism of the reaction are discussed.


Background: COVID-19 is a disease caused by infection of SARS-CoV-2 virus which leads to mortality due to respiratory failure. The progression of COVID-19 is more severe in patients with pre-existence morbidities, including liver disease. Recently, a few studie showed that liver cirrhosis patients with COVID-19 had a higher risk of mortality rather than liver cirrhosis patients without COVID-19 infection. Nevertheless, the study of survival COVID-19 in a patient with underlying liver cirrhosis is still limited. The aim of this study is to evaluate the survival of COVID-19 in adult patients with liver cirrhosisMethod: An observational study in Cipto Mangunkusumo Hospital was conducted. Patients with underlying liver cirrhosis between March 2020-January 2021 with positive confirmation of COVID-19 were enrolled in this study. Liver cirrhosis patients without COVID-19 were enrolled as a comparison. Both liver cirrhosis patients with and without COVID-19 were follow up at the time of hospital admission until 30 days outcome. Kaplan Meier and a log-rank test were conducted to evaluate the comparison of survival rate in liver cirrhosis patients with and without COVID-19. Multivariate Cox Proportional Hazard was conducted to identify the independent risk factors related to survival.Results: There were 22 liver cirrhosis patients with COVID-19 and 116 liver cirrhosis patients included in this study. Presentation of gender and age similar both of them. Predominantly males with average age were 57 years ± 13,60 for cirrhosis with COVID-19 patients and 53 years ± 12,75 for without COVID-19. The survival rate of liver cirrhosis patients with COVID-19 lower than liver cirrhosis patients without COVID-19  (35.8% vs. 67.2%, p-value 0.001). Median survival of liver cirrhosis patients with COVID-19 was 4 days (95% CI: 1-8 days), while median survival of liver cirrhosis patients without COVID-19 couldn't be reached since the survival rate of this group above 50%. Final model Cox PH showed that liver cirrhosis with COVID-19 (HR: 8.99; CI 95%: 4.55 – 17.80, p-value 0.001) and Child-Pugh class C (HR: 5.61; 95% CI: 2.76 – 11.40, p-value 0.001) were the independent risk factors associated with poor survival.Conclusion: The survival rate of liver cirrhosis patients with COVID-19 lower than liver cirrhosis patients without COVID-19. Liver cirrhosis with COVID-19 and Child-Pugh class C were associated with poor survival.


The southern part of the Tarim Basin is the most fragile eec-environment area in China. According to the archeological data, history references and paleoclimate information, its eco-environment has taken great changes during the recent 2000 years, which are characterized by the evolution and desertification of oasis and lead to many famous ancient cities having been abandoned and the south' silk road' has been moved southward. This paper analyses distribution and evolution of oasis, outlines the natural and man--made causes for the changes. The results show that oasis environmental changes are due to the aridization of climate before 20th century but mainly attribute to the human activities after into the 20th century. In order to prevent its eec--environment from further damaging, some adaptive measures should be taken timely: ① to develop and utilize water and soil resources rationally; ② to regulate the structure of agriculture; ③ to develop some preponderant resources such as solar and wind ; ④ to protect natural oasis effectively.


A single-staged, fixed-bed Wellman-Galusha gasifier coupled with a hot, raw gas combustion system and scrubber has been used to gasify numerous coals from throughout the United States. The gasification test program is organized as a cooperative effort by private industrial participants and governmental agencies. The consortium of participants is organized under the Mining and Industrial Fuel Gas (MIFGa) Group. This report is the eighth volume in a series of reports describing the atmospheric pressure, fixed-bed gasification of US coals. This specific report describes the gasification of River King Illinois No. 6 bituminous coal. The period of gasification test was July 28 to August 19, 1983. 6 refs., 23 figs., 25 tabs.


The main topic of this article is an analysis of Cassirer's concept of "symbolic forms". Cassirer, in his famous trilogy The Philosophy of Symbolic Forms (1923– 29), outlines this "polydimensional" concept with several contextual descriptions (somehow by analogy with implicit definitions of "primitive concepts" in axiomatic systems). Nevertheless, in this article a tentative definition of symbolic forms is presented, having in mind especially their connective function between the natural and cultural sciences. In the second part of the article, two more special topics are discussed: 1. the influence of Einstein's (and F. Klein's) concept of invariance on Cassirer's symbolic forms; 2. the influence of Hegel's dialectical Wissenschaft on Cassirer's historical variant of Neo-Kantism; in spite of the fact that Cassirer does not accept Hegel's logicism and his concept of the "absolute science", he still remains within the epistemological paradigm of the "gradual", hierarchical cognitive process, which culminates, otherwise than as in Hegel, in exact sciences and mathematics – i.e., in a modern version of Leibniz's mathesis universalis.


In the interaction of K-ketyl and the benzophenone dianion with condensation occurs with aniline, leading to the formation of a Schiff base of diphenylmethinaniline. It flows sideways cleavage of the C-C bond of K-ketyl benzophenone to form benzoic acid, as well as the reduction product – benzhydrol


1. Garcia-Lledo, M, Feinbaum, C and Alio, JL. Contact lens fitting in keratoconus. 2006: 7(2). 2. Schornack, MM and Patel, SV. Scleral Lenses in the Management of Keratoconus. Eye & Contact Lens. 2010:36(1). 3. Schornack MM, Baratz, MD, Patel, SV and Maquire MD. Jupiter Scleral Lenses in the Management of Chronic Graft Versus Host Disease. Eye & Contact Lens. 2008:34(6). 4. Schornack, MM, Pyle, JP and Patel, SV. Scleral Lenses in the Management of Ocular Surface Disease. Ophthalmology. 2014:121. CONCLUSIONS RESULTS


Self-monitoring, self-repairing aerospace vehicles require modular, flexible and adaptive sensing and communication networks. In general, a modular (multi-cellular) sensing and communication network is expected to detect and react to impact location, energy and damage over a wide range of impacts. It is critical that global response emerges as a result of interactions involving transfer of information embedded locally, avoiding single points-of-failure. This work presents mechanisms ensuring self-organisation of autonomous cells into robust and continuously connected impact boundaries. The spatiotemporal stability is demonstrated for a variety of cell shapes in a dynamic environment with varying energy dissipation and damage probability models.


Summary

Hydranencephaly is well recognised in several domestic animals, especially ruminants, but is virtually unknown in the horse. This case report describes a premature filly foal that on the day of delivery was found with a severe neurological disorder that initially improved but then progressively worsened. The foal was subjected to euthanasia on humane grounds and post mortem examination revealed somewhat asymmetric but bilateral destruction of the telencephalon identified as hydranencephaly. The possible causes of hydranencephaly in foals are discussed.


Took the fresh extraction lonicera edulis turcz juice as raw material,thermal degradation dynamic of vitamin C was discussed at the different temperatures,avoid light and continuous filling nitrogen conditions,for optimization controling the deep-processing conditions and providing the scientific basis for the shelf-life forecast.The result showed that the vitamin C in lonicera edulis turcz juice was unstable with heat treatment,which degradation was a first order degradation dynamic process.With the thermal degradation rate constant and activation energy(Ea)analyze showed that filling nitrogen treatment could increase the stability of vitamin C in lonicera edulis turcz juice,light was more effect than oxygen to the degradation of vitamin C.


Helicobacter pylori infection is one of the most common chronic infections worldwide, being most prevalent in developing countries and lower socioeconomic classes. Its prevalence ranges from 7% to 90%, depending on the cohort studied [1]. In addition to causing gastric and duodenal ulcers [2], it increases the risk of gastric cancer [3]. Furthermore, H. pylori infection causes changes in the physiology of the gastrointestinal tract. H. pylori infection is associated with duodenal acidification, increased gastrin secretion, and increased exocrine pancreatic secretion [4]. Although these changes – such as increased pancreatic stimulation – could be associated with an increased risk of acute pancreatitis or a more severe course of the disease, the association between H. pylori infection and acute pancreatitis has not been thoroughly studied. In a previous study, we measured the prevalence ofH. pylori infection in patients with their first alcoholinduced acute pancreatitis and compared it to that of controls with similar high alcohol use but no history of acute pancreatitis [5]. The rate of infection was similar in both groups studied. The objective of this study was to ascertain whether H. pylori infection is associated with a more severe course of acute pancreatitis. We reanalyzed prospectively collected patients of a previous study [6]hospitalized foracutepancreatitis.All etiologies of acute pancreatitis and both patients with theirfirstor recurrentepisodewere included.Altogether 231 patients were studied. One hundred sixty-eight (73%) were male and the median age of the patients was 48 (range 17–90). Acute pancreatitis was caused by alcohol in 130 (56%) patients, gallstones in 46 (20%), other known causes in 17 (7%), while 38 (17%) remained idiopathic. One hundred fifty-two (66%) patientshadtheirfirstacutepancreatitis.Theprevalence of H. pylori infection was obtained by measuring the IgG antibodies from the sera using EIA antigen test.


It is known that the concepts of continuous norm and of absolutely continuous norm do not coincide. There exists a space in which all functions possess continuous norm but not all functions possess absolutely continuous norm. In this paper we construct an extremal example of a Banach function space in which all functions have continuous norm but only the zero function has absolutely continuous norm.


AbstractKnowledge production in US academic adult education (1945–70) altered significantly in the light of apparently pervasive and permanent post-war economic and cultural change forces that transformed both the individual and the social. This paper explores this in relation to a post-war knowledge explosion that equated knowledge with productivity in a way that raised serious questions around which knowledge was of most worth. It reflects critically on the cultural politics of field knowledge production, which equated building a techno-scientific knowledge base with building collateral to leverage dominant cultural space and place. From this perspective, the paper considers the status of social education. It examines the location of liberal education, the locations of history and philosophy as foundational knowledges, and the status of US adult educational research during the techno-scientific turn. It concludes with a postscript suggesting the cultural space and place of US academic adult education in...


Purpose The objective of this study was to : assess the efficacy and clinical outcome of vaginal wall sling in the management of women with stress urinary incontinence. 1) Materials and Methods A total of 37 : patients with stress urinary incontinence underwent vaginal wall sling procedure by a single surgeon from January 1998 to December 2001. All patients were evaluated preoperatively with detailed history, physical examination, urinalysis, abdominal ultrasonography, Q-tip test and stress provocation test. The 4 sutures comprising vaginal wall sling (two at the level of mid-urethral complex and two at the level of bladder neck) provide a rectangle of support and compression from the bladder neck to the mid-urethra. The efficacy and clinical outcomes of this procedure were evaluated. Results With a mean follow-up of 19.2 : months(5 to 46 months), 30 patients(81%)


Is0 thermal V-I characteristics of Bil.8 Pbo.2 Sr2 Ca:, CUB 0, high temperature superconductors (HTSCs) have been systematically studied. Below the irreversibility temperature T,(H), two important features were observed: 1) Both positive and negative curvatures can coexist in the same isothermal V-I curve, so it is different from the scaling behavior V ctexp(-(Jo/J)p). 2) The activation volume off lux motion is found temperature dependent as (l-T/T,(H))-'" with v about 0.5. This behavior supports the existence o f a two-dimensional secondary phase transition below H,z(T) in this &-based HTSCs.


Low energy ion implantation technology was used in mutation breeding of Hericium erinaceus.The growth speed of the Hericium erinaceus hypha is as an index to study the influence of the pulse lasting time of N~+ ion implantation.The result shows that the growth speed of Hericium erinaceus hypha presents "saddle shape" curve,which was descend first,then rising up and descend again when the pulse time lasts for longer and longer.It is concluded that the pulse time obviously influence N~+ ion implantation.When the dosage keeps the same.


TRAF3 (TNF Receptor Associated Factor 3) is a regulator of NF-κB signaling, acting mainly as an inhibitor of the alternative NF-κB pathway through the interaction with other TRAF molecules and the downregulation of NIK (MAP3K14) kinase. While NF-κB has a well-established role in breast cancer development and progression, TRAF3 which acts as a ubiquitin-ligase in the NF-κB cascade has never been studied in mammary carcinomas. Here by employing breast cancer cell lines in invasion and colony formation assays, we show that TRAF3 forced expression inhibits aggressive traits of breast cancer cells. In addition, immunohistochemistry (IHC) for TRAF3 protein in breast cancer FFPE samples and analysis of TRAF3 gene expression from publicly available data sets, indicates that TRAF3 mRNA and protein expression in breast cancer tissue correlates with Recurrence Free Survival (RFS), Overall Survival (OS) and other clinicopathological parameters such as Histological Grade and proliferation index (ki-67). To our knowledge this is the first report on TRAF3 protein in breast cancer providing preliminary evidence for an inhibitory role of this protein in breast cancer development and progression.
 Citation Format: Anastasios Papanastasiou, Chaido Sirinian, Maria Theakou, Stavros Peroukidis, Dimitrios Chaniotis, Haralabos Kalofonos, Angelos Koutras. TRAF3 as a regulator of breast cancer aggressiveness [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P2-26-03.


SUBTITLE: RECORD FIRST-QUARTER PROFIT TURNAROUND SPURS NORTHWEST TO RESUME HIRING AFTER A THREE-YEAR HIATUS: BUT THE JOB COMPETITION IS STIFF.


The invention discloses a distance-based high-accuracy global outlier detection algorithm. The algorithm includes: detecting a global dataset by blocking, wherein each block of data is called a data block; calculating the distance between each object p in each read data block and each object in the global dataset, calculating the outlier degree and the implicit outlier degree of each object p, if the implicit outlier degree of the object is smaller than a threshold, rejecting the object out of dataset and stopping calculating the distance between the object and rest objects of the global dataset. According to the distance-based high-accuracy global outlier detection algorithm, outlier influences can be reduced while detection accuracy can be improved on the premise of reserving of distance-based universality.


Thermodurics are 'heat resistant' bacteria capable of surviving pasteurisation and have the potential to cause quality and shelf life issues in dairy products. They are ubiquitous in the environment and can be present in a wide range of sources. Managing thermoduric levels in milk can be challenging, though focus on hygiene of the herd and milking equipment should achieve effective control.


Current advances in CT dose reduction and image quality improvement mechanisms rely on moving towards a more patient / image specific approach. For example, statistical reconstruction algorithms tailor reconstruction weights to patient attenuation values and CT protocols make use of different kVp and mAs settings for different body regions and sizes. In this paper, for the first time to our knowledge, experimental results are presented in which a dynamic bowtie filter was used to tailor the imaging dose during a CT acquisition. The device used to implement a dynamic bowtie is referred to as a digitial beam attenuator (DBA). A non-DBA (non-modulated) CT scan was also performed for comparison. At half of the imaging dose, the noise uniformity of the DBA CT images was 37% better than the non-DBA scan. The use of a dynamic bowtie filter may also prove useful in photon counting CT (PCCT) where high fluence rates and large differences in fluence across projections and from view to view make implementing PCCT difficult. Results are presented in this paper showing dynamic range requirements of 7.9 and 13.8 for DBA and non-DBA scans respectively. The results also show that when using the DBA, the dose delivered can be reduced by 1.9 times for the small phantom used in this study. The differences in dynamic range and dose are somewhat small compared to what would be seen clinically due to the small size of the phantom used in the study. Using a more clinically relevant phantom, dynamic range differences of 22 times and dose reductions on the order of 4 times can be observed in which the effects of the DBA will be more dramatic.


The first three chapters of this thesis provide an introduction, an overview of the 'young novice driver problem' and a theoretical framework of hazard anticipation. In Chapter 2, an overview is presented of factors that indirectly have an influence on how young novice drivers anticipate hazards in traffic. In Chapter 3, a cognitive neuropsychological framework of hazard anticipation is introduced that has been the theoretical basis for the empirical studies reported in the Chapters 4, 5 and 6. In Chapter 4, an exploratory study about the differences between young novice drivers, older novice drivers and experienced drivers in hazard anticipation is presented and discussed. Based on the results of this exploratory study two hazard anticipation tests have been developed that are presented and evaluated in Chapter 5. Chapter 6 is about the development and evaluation of simulator-based hazard anticipation training. In the last chapter of this thesis (Chapter 7), an overview of the key findings is provided and the results are discussed in the light of the theoretical framework (presented in Chapter 3).


The invention discloses a medicine and food homology biological composition for thrombolysis, lipolysis, improving microcirculation, nourishing the kidney, protecting the liver, purging toxin and maintaining the skin, and a preparation method for an oral liquid thereof. The composition comprises according to the weight parts: 80-120 parts of mushroom, 40-60 parts of hawthorn, 90-120 parts of semen cassiae, 130-150 parts of balsam pear, 45-60 parts of Chinese yam, 90-110 parts of the root of kudzu vine, 95-110 parts of bitter buckwheat, 100-110 parts of pollen, 180-225 parts of sea cucumber, 48-55 parts of the fruit of Chinese wolfberry, 27-32 parts of America ginseng, 28-35 parts of longan pulp and 46-53 parts of gynostemma pentaphylla. The raw materials are extracted with water, concentrated, encapsulated and sterilized to obtain the oral liquid. The product can activate the nerve function of the whole body, improves the brain function and mental state, activates and repair cells of the whole body, increases the immunologic function of the organism, is safe, independent and has no side effect proved by observation.


We read with interest the article entitled ''Admission Endocan Level may be a Useful Predictor for In-Hospital Mortality and Coronary Severity Index in Patients With ST-Segment Elevation Myocardial Infarction'' by Kundi et al. They showed that high endocan levels during hospital admission are an independent predictor of a worse cardiovascular (CV) outcome and a high SYNTAX score in patients with ST-segment elevation myocardial infarction. Endocan is an immunoinflammatory marker linked to endothelial dysfunction and may be a predictor of CV disease events. Also, Cimen et al found that endocan levels in patients with microvascular angina were higher than that of the control group. Besides, Cimen et al excluded patients with the conditions such as acute coronary syndrome, history of previous myocardial infarction, coronary artery bypass grafting, percutaneous coronary intervention, secondary hypertension, severe valvular disease, congestive heart failure (New York Heart Association Classes III-IV), renal and hepatic dysfunction, any active inflammatory disease, atrial fibrillation, and malignancy. However, Kundi et al do not report any data about exclusion criteria in the study patients. They specified that only 9 patients were excluded because percutaneous coronary intervention was not performed. Likewise, hypertension rate was significantly different between the 2 groups. Hypertension is a major factor that can be associated with inflammation. We think that the authors should add this variable to the multivariate analysis.


Age of menarche is a determinant factor of cardiometabolic risk, adiposity and stature at adulthood. However, little is known about the transgenerational effects of age of menarche, especially beyond childhood of any offspring, and the studies remain limited to anthropometric outcomes in children at birth or before adolescence. In the present study, we aim to investigate the relationship of maternal age at menarche (MAM) with anthropometric and metabolic parameters in the young adult offspring (aged 15–35 years) in a Persian population.


The drive of building new socialist countryside is to establish a new countryside governance system that fits in with new developments in rural areas and promote the social transformation in countryside and coordinated development of rural and urban areas.As it concerns both economic growth and social development the construction of new socialist countryside can never be achieved in one attempt,it requires adaptations in drafting the strategic development plans as well as a policy system and a governing structure that support these changes.Therefore,it is urgent and essential to reform institutional and organizational factors that hamper economic growth and social development so as to ensure a sustained construction of new socialist countryside.


Bibliometric studies have been carried out to assess the research productivity in the different field of knowledge. Kingdom of Saudi Arabia plays a leading role in the field of medical research in all Arab States. There are 64 universities and degree awarding institutions in KSA, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) established in 2005. The aim of this study to assess the oncology research outcome having an authorship affiliated with KSAU-HS, its teaching hospitals, and King Abdullah International Medical Research Centre (KAIMRC) published during the inception of the university to Dec 2015. Data retrieved from Institute of Scientific Information (ISI) web of science, InCiteTM Database of Thomson Reuters, which produced the list of 775 research documents published in 346 different journals, out of these 45 articles are written on the subject of oncology in 19 different journals. Majority of articles (91.11%) are written in collaborative efforts. In 33 (73.33%) publications, the principal author belongs to KSAU-HS, its associated hospital and research center. Almost half of the research papers (55.55%) are written in collaboration with researchers at other universities/hospitals and organizations. This study is only based on the bibliography produced by ISI's Web of Science database. The articles produced by KSAU-HS may be more than this number. The data was analyzed by using MS-Excel 2010.


While scientific and technological progress and economic development have improved the state of human life, they have also brought a series of hazards to human survival. Therefore, sustainable development has become an inevitable trend for development in various fields. Patchwork art is a typical traditional art form. No matter now or in the future, only by absorbing the essence of culture, deeply exploring the harmonious relationship between man and nature, and adhering to the road of sustainable development can we realize the vitality of modernization. This article focuses on the concept of sustainable development and provides theoretical knowledge and methodological guidance for modern patchwork art design. Taking the work "Hui Yu Men Ting" as an example, it discusses the sustainable design research of the use of waste denim clothing for the creation of patchwork art from the aspects of material selection, creative concept, and expression techniques.


Abstract We consider two kinds of small subsets of the real line: the sets of strong measure zero and the microscopic sets. There are investigated the properties of these sets. The example of a microscopic set, which is not a set of strong measure zero, is given.


Cracks are one of the main causes of structural damage to roads and buildings. Compared to traditional crack detection methods, recently the application of deep learning methods for crack detection is gradually increasing, which achieve more accurate and more efficient results, and have high generalization capability. In order to improve the accuracy of crack detection, this paper mainly proposes a crack detection algorithm that incorporates shuffle attention mechanism instead of the convolution module, and fuses focal loss and dice loss based on Deeplab V3+. Furthermore, to focus on the crack pixels, we propose a dynamic compensation weight with the focal loss function. We finally validated our algorithm on two public datasets, and achieved superior results.


Eliminating the need for extensive wiring between sensors, actuators and a controller could reduce the cost and enhance the attractiveness of control systems for civil structures. In this study, wireless sensors are proposed for a structural control system with the wireless sensors responsible for the collection of state response data, calculation of control forces, and the issuing of command signals to actuators. While wireless sensors are attractive because of their easy installations, they are limited by the amount of bandwidth available in the wireless communication channel. To address this limitation, the on-board computational resources of wireless sensors are leveraged to alleviate the need for continued use of the wireless channel. Specifically, redundant Kalman state-estimators are encoded in each wireless sensor to estimate the state response of the structure, using only local output measurements. At each time step, the estimated state is compared to the measured system output; when the estimation error exceeds an established threshold, only then is the wireless communication channel used to broadcast updated state information to the remaining wireless sensors. This partially decentralized control method is validated using a 20-story building modeled in a simulation environment. Furthermore, an experimental study is conducted using a three story test structure in which magnetorheological dampers and wireless sensors are installed for the purpose of real-time feedback control during base excitation.


We extend the $\nu$-metric introduced by Vinnicombe in robust control theory for rational plants to the case of infinite-dimensional systems/classes of nonrational transfer functions.


For distance education students, the learning management system (LMS) is their university. An essential document that students access from their LMS is the course syllabus. The standard information included from university support services such as the library can be dry, outdated, and not useful for students. In addition, pulling the information into the syllabus without a link back to the original source risks a syllabus riddled with broken links and incorrect information relayed to students. The project described here focuses on the creation of a LibGuide for online students that functions as both a resource and a portal to other essential resources. This LibGuide is kept current and userfriendly for students and is automatically inserted in all syllabi for distance education courses. This effort has significantly increased use of the LibGuide, a greater awareness of library integration possibilities, and has taken the burden off of academic departments to keep library information current and links working. The reader should walk away with a rationale for why this project is worthwhile and an understanding of how to complete a similar initiative.


A 1.1-GHz fractional- N frequency synthesizer is implemented in 0.5-??m CMOS employing a 3-b third-order ???? modulator. The in-band phase noise of -92 dBc/Hz at 10-kHz offset with a spur of less than - 95 dBc is measured at 900.03 MHz with a phase detector frequency of 7.994 MHz and a loop bandwidth of 40 kHz. Having less than 1-Hz frequency resolution and agile switching speed, the proposed system meets the requirements of most RF applications including multislot GSM, AMPS, IS-95, and PDC.


This is an announcement of conjectures and results concerning the generating series of Euler characteristics of Hilbert schemes of points on surfaces with simple (Kleinian) singularities. For a quotient surface C^2/G with G a finite subgroup of SL(2, C), we conjecture a formula for this generating series in terms of Lie-theoretic data, which is compatible with existing results for type A singularities. We announce a proof of our conjecture for singularities of type D. The generating series in our conjecture can be seen as a specialized character of the basic representation of the corresponding (extended) affine Lie algebra; we discuss possible representation-theoretic consequences of this fact. Our results, respectively conjectures, imply the modularity of the generating function for surfaces with type A and type D, respectively arbitrary, simple singularities, confirming predictions of S-duality.


Vegetation changes in the salt marshes of the Schleswig-Holstein Wadden Sea National Park are measured annually since 1991 in relation to sea level rise, vegetation changes and salt marsh management. In total 249 permanent plots were established along transects with a concentration to three different locations along the coast, namely the Hamburger Hallig, the salt marshes of Westerhever and on the island of Trischen. Annually the vegetation composition and the cover of the species is measured using the LONDO scale. The measurements are part of the Trilateral Monitoring and Assesment Programm (TMAP) within the trilateral Wadden Sea Cooperation. The data provide a baseline for further studies of salt marsh succession in relation to marsh management and coastal protection activities. This report describes the available content in the TMAP Wadden Sea Vegetation Database (GIVD ID EUDE-033).


We present the discovery of a late appearing polymorph of the nutraceutical pterostilbene and analyzed computationally the intermolecular interactions observed in its crystal structure to explain its higher stability with respect to previously known forms.


In times like these, a new ethico-political ideal is required to contest the adequacy of dominant understandings of social interaction as matters of choice and rational decision-making and in contesting these understandings encourage us to imagine social alternatives. We wish to make a contribution to this project of expanding the universe of political discourse as a means to invigorating ethico-political debate. A range of existing vocabularies — the languages of trust (and relatedly respect), care and associated concepts, including corporeal generosity — are currently put forward as the means to contest the dominance of neo-liberal premises about `atomistic individualism'. While many of these accounts focus on nation-states, others attend to an emerging global community. Nevertheless, we have some reservations about these languages and their premises. In our view they tend frequently to locate the `problem' in the character of citizens. We also make the case that such languages and their associated political agendas reinstate aspects of social hierarchy that mimic neo-liberal conceptions of autonomous individualism. Central to our critique is the claim that the problematic aspects of these existing languages of (inter)connection are due to an attenuated understanding of embodiment and an inadequate dialogue between the socio-political and embodiment. It is this inadequate dialogue we wish to redress. In this paper we offer a new ethical ideal called `social flesh' to ground an alternative politics for reconfiguring exploitative social relations. As an ethico-political starting point, `social flesh' highlights human embodied interdependence and in the process configures a new, more transformative political vision. It draws attention to shared embodied reliance, mutual reliance, of people across the globe on social space, infrastructure and resources. Insistence upon this shared reliance underpins a profoundly levelling perspective, a radical politics.


To investigate the adaptive response of low doses of gamma-rays to challenge doses of Mitomycin C(MMC) on the splenic lymphocytes in mammalian, mice were irradiated with inductive doses of 50, 75,100mGy 6h before challenge dose of MMC (1mg/kg). Observations were made on efficacy of splenocyte count, cell cycle progression, DNA synthesis in number of splenocytes, Flow cytometry, the splenic lymphocyte transformation induced by Con A and LPS. The number of splenocytes in Group B(1mg/kg of MMC) was significantly lower than that the control(Group A). The number of splenocytes in Group C, D and E (50-100mGy + MMC) was significantly higher than that in Group B. Both the percentages of G0/G1 and S phase cells in Group D and E were lower and higher than that in Group B in cell cycle progression of the splenic lymphocyte transformation induced by Con A. Significant changes of the numbers were found in the LPS treated groups (except G0/G1 phase of Group E). The results showed adaptive response of low doses of γ-rays to challenge doses of MMC on number of splenocytes and cell cycle progression of the splenic lymphocyte transformation induced by Con A and LPS in mice.


In this paper, we describe various custom digital ICs fabricated using our InP DHBT technology, operating at a clock rate up to 50 GHz. We also present the results of some 40+ Gbit/s system experiments these circuits have enabled.


The report of the eighteenth National Congress of the PPC puts forward"let the power operatie in the sunshine ". It has a very important significance for establishing open and transparent judicial information disclosure system to curb judicial corruption. In order to realize the judicial information disclosure system,it is necessary to accurately define the connotation of"judicial information disclosure"and the scope and content of judicial information disclosure as well. We must clarify the relationship between judicial information disclosure and the relevant systems. After the reconstruction of the basic theory of judicial information disclosure,we should establish and improve relevant legislation to improve the system of judicial information disclosure.


Summary form only given. The increasingly demanding application of erbium-doped fiber amplifiers (EDFA) in fiber optic communication systems (including solitons), requires a deep understanding of the effects of the pump laser on the optical properties of the amplifier at the signal level. Amplification provides by EDFAs is produced by optically pumping an absorption band to provide signal gain in the emission band. Promoting carriers to upper energy levels modifies the optical properties of the amplifier. There has been few studies on the pump induce refractive index change at the signal level in EDFAs-all focused on the pump-induced effects on the linear index of refraction, and none on the nonlinear index of refraction n/sub 2/. The theory for the nonlinear susceptibility in the presence of a pump laser in a quasi-two-state system was developed. We use a previously described technique called induced grating autocorrelation two-beam coupling, IGA-TBC to verify the results.


This paper provides a short description of three European projects in which Silicon-on-Insulator based high index contrast waveguide devices play a prominent role. These projects include the European Network of Excellence FP6-ePIXnet, the European research project on on-chip optical interconnect FP6-PICMOS and the European Space Agency project on Multi-Gigabit Optical Backplane Interconnections. © 2005 Microoptics Group (OSJ/JSAP)