The purpose of this study was to investigate the effect of swimming on kidney morphology and expression of HSP70 of rats with aggressive behavior.42 healthy male SD rats were randomly divided into following 5 groups after training,which are:quiet control group(group A,n=8),communal swimming group(group B,n=8),aggressive behavior control group(group C,n=8),aggressive behavior and swimming group(group D,n=8)and invasion group(group E,n=10).The attack model is established by the ways of feeding the rats separately and let rats attack.Then the rats in the group B and group D were required to have swimming training with 8 weeks.Moreover,made slices of rats′kidneies and HE stain were made after drawing materials.The rats′kidneys morphology and expression of HSP70 were measured by Western blotting and immunohistochemical staining.The rats′kidneys in group C and group D had many morphological changes,especially in group C.The protein of HSP70 of rats′kidneys in group B is much less than in group A(P0.01).However,the protein of HSP70 of rats′kidneys in group C is much morethan in group A(P0.01)and group D is lower than group C(P0.01).The two-factor variance analysis made it obvious that swimming and aggressive stress have a huge impact on the protein of HSP70 of rats′kidneys.Moderate intensity swimming exercise can adversely resist the stree response of kidney and weaken sharp morphological changes in rats with aggressive behavior.


The present study attempts to investigate the determinants of corporate social performance (CSP). Specifically, it examines the relationship between organizational slack and CSP using the behavioral theory construct of attainment discrepancy. The results show that organizational slack and attainment discrepancy in financial performance are necessary precursors to the firms' undertaking CSP investments.


In order to develop an ion-exchanger for industrial use, a new compound, titanium dihydrogen bis (phosphate) hemihydrate, was prepared by means of a reflux between titanium phosphate and concentrated phosphoric acid; then the conditions of synthesis and the ion-exchange properties of the products were investigated. The amorphous titanium phosphate used as the starting material was formed by the reaction of titanium tetrachloride with phosphoric acid in diluted hydrochloric acid. The phase equilibrium of the TiO2–P2O5–H2O system has been studied at the refluxing temperatures of the mother liquors. The solid phase in equilibrium with the mother liquor containing 13–64% P2O5 had the components of TiO2 (29–32%), P2O5 (53–54%), and H2O (15–16%); its composition was TiH2(PO4)2·H2O, which had already been known, but the solid phase in equilibrium with the mother liquor containing more than 64% P2O5 had as components TiO2 (31–32%), P2O5 (57–58%), and H2O (10–11%); therefore, its composition corresponded to TiH2(P...


Solar radiation is necessary for the proper development, maturing and functioning of the human body. A period of time when there was a deficit of solar radiation in the city of Krakow was identified and characterized. The period was selected based on diurnal values of cloudiness and sunshine duration from the years 1884–2009. An analysis of the impact of the deficit of solar radiation on the health and well-being of city dwellers was performed. Proposals were put forth on how to prevent the consequences of the lack of sunshine.


This papers considers the problem of maximizing the load that can be served by a power network. We use the commonly accepted Linear DC power network model and consider wo configuration options: switching lines and using FACTS devices. We present the first comprehensive complexity study of this optimization problem. Our results show hat the problem is NP-complete and that there is no fully polynomial-time approximation scheme. For switching, these results extend to planar networks with a aximum-node degree of 3. Additionally, we demonstrate that the optimization problems are still NP-hard if we restrict the network structure to cacti with a maximum degree of 3.


Background: The effects of the COVID-19 pandemic on birth rates are not yet known and only very few studies have addressed this issue. However, the pandemic has triggered a massive uncertainty in several dimensions, leading to disruptive economic and social changes that could affect trends in fertility rates in more than 170 countries. Given that the pandemic could have significant consequences for the future population, this paper proposes some approximations on future scenarios in fertility trends.

Methods: Based on a VAR model, we exploit the variations in total fertility rates and changes in real GDP observed in recent years, as well as the economic growth projections by the Monetary Fund International.

Findings: The COVID-19 pandemic will accelerate declining fertility trends in several high- and middle-income countries, perhaps to unprecedented levels, thus uncovering major failures in motherhood policies and institutions. In low-income countries, the effects of the pandemic would be less. Total fertility rates in the world could be below the replacement level of 2.1 by 2040. Portugal, Spain, Greece, Finland, Italy, Ireland, and the United States could even have total fertility rates below 1. The possible patterns of fertility convergence observed in recent years could also be significantly altered.

Interpretation: Unlike other lethal plagues in history, in which high mortality rates determined subsequent birth behaviors, we suggest that uncertainty triggered by the COVID-19 would play a central role in explaining future fertility patterns, as the economic and social consequences of the pandemic extend for several years. Given their consequences for the future population, governments should place fertility policies as part of their core concerns and strategies for recovery from the pandemic.

Funding Statement: No funding was provided for the production of this research.

Declaration of Interests: The authors declare that they have no conflict of interest(s).


A new single phase earth fault detection technique based on wavelet packet analysis is introduced in this article: The zero sequence power components are formed of the wavelet packets coefficients of the zero sequence voltage and currents, and are used to be the signs of fault detection, the fault detection is accomplished with comparing the phases of the power components. A small Petersen coil grounded system is simulated in the article, analyzing and computing the simulation results, the rightness and availability is proved.


The traditional market activation businesses which are various with the public consistency are hosting from the early 2000's. However, the effort that the traditional market analyze the individual market characteristic and finds the activation influence factor before is insufficient. This study collected the big data information about the consumer in this. Collected data were visualized on a real time basis. And the network platform through this drawing the activation plan was built. Through this, the problem that it was unable to grasp the demand for the characteristic that it have and market accurately is possible with the complementary. Present the contents of research about the various contents expressed in order to visualize the living quarter of the traditional market users and comsuption behavior on a real time basis and understand easily analyzed data through the network-based open platform. This makes the market individual case tailored strategy program establishment possible. As to this platform, as the time flows, the accumulated data amount increases gradually and through this, the time series analysis is possible. Moreover, the verifying information in the present time is possible and the information offering which it is usable to not only consumer but also dealers is possible. Moreover, it is better than the current through data, there is the scientific importance as the bilateral open platform having an effect on the activation of the traditional market through the guide information which can be built till the activation plan.


Summary 1. Hourly intraperitoneal administration of angiotonin to rats pretreated with DCA and salt elicited edema, convulsions, a positive fluid balance and increased fluid intake, together with proteinuria, visceral hemorrhages and acute necrotizing lesions in small arteries and arterioles. 2. The same series of changes occurred in similarly pretreated rats given renin subcutaneously. 3. We conclude that the vascular lesions elicited by renin in sensitized animals are very likely due to the action of renin as such, effected by liberation of angiotonin and are not, as hitherto seemed possible, attributable to vasculo-toxic factors in renin preparations or to an action of renin independent of formation of angiotonin.


As a relatively new research field, community smells have received a lot of attention in recent years. This study aims to identify, evaluate, and synthesize previous works on community smells using the Systematic Literature Review (SLR) Protocol. Initially, a total of 125 research papers were retrieved from three electronic databases based on our defined search string. 21 papers were finally selected based on the selection criteria to be synthesized and analyzed in detail. After analyzing the documents, the research trends and approaches adopted in community smell research are discussed and presented Besides, the gaps in this domain have been identified. We concluded that more studies need to be done in this specific area to address the gaps.


Student leaders are the important work force which the college student management and education in the process to rely on.They are not only the bridge and link between schools,teachers and ordinary students,but also the reserve of schools and social management cadres.Grasping and analyzing their basic conditions,the growing demand and group identity is significant.In this paper,the group identity of the student leaders has been sorted out,and their needs and deficiencies are understood through research and discussion about their positioning in the self-awareness,growth and success.And by drawing on the experience of student affairs management in the United States such as "student services","student development ","student learning",we put forward some suggestions in team-building and personnel training of the current student leaders etc..

Key words:
Student leaders; Group characteristics; Student services; Student development


We report the synthesis and characterization of poly(dimethylaminoethyl methacrylate)-block-poly(styrene) (PDMAEMA-b-PS) diblock copolymers by RAFT polymerization. These polymers form uniform spherical micelles with dispersities less than 0.05 upon addition of aqueous buffer to polymer solutions in DMF. Potentiometric titrations under constant ionic strength conditions yield the first rigorous ionic-strength-effective pKa correspondence for PDMAEMA homopolymers and micelles. We demonstrate that the effective polymer pKa increases monotonically toward the monomer pKa with increasing ionic strength, but decreases slightly upon association of polymer chains into micelles. We further characterize the pH- and ionic-strength-induced contraction of the micelle coronas in buffered aqueous solutions. In monoprotic buffers, the micelle corona behaves as a salted osmotic brush, as has been observed for other block polyelectrolyte micelle systems in unbuffered solutions. In polyprotic buffers, however, we observe an ...


The increase of environmental concern as a result of corporate citizenship spreads the applications for collecting end-of-life products to a broader extent. This trend raises the issue of reverse logistics (RL), one of the major challenges in sustainability. One of the greatest barriers for successful RL is the difficulty of developing an accurate system to forecast the amount of product returns. Advanced techniques such as learning systems are proven very helpful for increasing the performance of forecasting methods. This article proposes an "early warning system" for waste collection operations in the electrical and electronic equipment industry. The main goal is to develop a supportive system for manufacturers and authorized organizations that provides foresight about their potential to reach the target values proposed by environmental regulations. The proposed forecasting system is based on an artificial neural network (ANN) model with five basic factors affecting the amount of product return: sales amount, number of houses, electricity consumption, the GINI coefficient (coefficient showing income distribution inequality) and population density. An application of the system is shown for Marmara Region, Turkey, and the compliances of all the big cities in the Marmara Region are checked for target values. The researchers' findings show that only five of eleven cities will be successful at fulfilling the required target e-waste values addressed by WEEE regulations.


As a renewable energy source, small hydropower has significant effects on improving the voltage along the grid. This paper first builds a hydropower grid-connected basic model based on the PSCAD simulation software platform, and conducts research on small hydropower grid-connected operation. Then set different parameters and adjust the model to simulate the state of small hydropower grid-connected operation in various environments. Finally, the control variable method was used to change the output of small hydropower and the access point of small hydropower to the grid, and the impact of small hydropower access on the grid voltage was compared and analyzed.


The Inverse Scattering Transform (IST) for the defocusing vector nonlinear Schrödinger equation (NLS), with an arbitrary number of components and non-vanishing boundary conditions at space infinities, is formulated by adapting and generalizing the approach used by Beals, Deift and Tomei in the development of the IST for the N-wave interaction equations. Specifically, a complete set of sectionally meromorphic eigenfunctions is obtained from a family of analytic forms that are constructed for this purpose. As in the scalar and two-component defocusing NLS, the direct and inverse problems are formulated on a twosheeted, genus-zero Riemann surface, which is then transformed into the complex plane by means of an appropriate uniformization variable. The inverse problem is formulated as a matrix Riemann-Hilbert problem with prescribed poles, jumps and symmetry conditions. In contrast to traditional formulations of the IST, the analytic forms and eigenfunctions are first defined for complex values of the scattering parameter, and extended to the continuous spectrum a posteriori.


This paper provides a brief description of the Brazilian Atomic Time Scale System that generates the UTC(ONRJ). Also describes the international comparison of the UTC(ONRJ) in the last year by using data from Circular T and UTC rapid.


Objective Investigating the early results of percutaneous transluminal angioplasty of chronic lower-limb ischemia in patients with chronic renal failure. Background The concern that endovascular treatment of chronic lower-limb ischemia in patients with chronic renal failure is gaining popularity nowadays since the increase in morbidity and mortality rates in bypass surgery makes the procedure difficult for these patients. Patients and methods In total, 40 limbs in 40 consecutive patients (28 male, mean±SD age 59.65 ± 8.54) were analyzed, 28 with lesion, either gangrene or ulcer, and 12 with rest pain. The follow-up of healing and foot vascularity was done at regular periods and up to 1 year as ABI was not a good indicator for follow-up because of the high false results due to severe calcification. Results After 12 months, the end results of the study are as the following: 10 (25%) cases were relieved from rest pain, another 12 (30%) cases had healed lesion, and three (7.5%) cases had major amputation, 11 (27.5%) cases had return of the same complaint as preoperative by the end of 12 months. Conclusion Despite improvement in endovascular techniques and their increasing utilization for lower-extremity revascularization, peripheral revascularization in chronic renal-failure patients has not led to high limb-salvage rate. Poor outcomes may be related to the severity of ischemia on presentation, the cumulative burden of the atherosclerotic disease, and the distal location of the disease.


Homomorphic encryption schemes emerged as the solution to the problem of secure data processing in the cloud. A fully homomorphic encryption scheme is constructed by using a Bootstrappable somewhat homomorphic encryption scheme, i.e. an encryption scheme that can homomorphically evaluate its own decryption circuit. In this paper, a somewhat homomorphic encryption scheme, based on lattices, is implemented and used for executing morphological operations over encrypted binary images. Moreover, a quantitative study to verify the influence of the implemented scheme's parameters on the execution times (key generation, encryption, decryption and morphological operations) and on the number of operations that the scheme is able to perform without leaving the decryption radius is performed.


The method of surviving sisters for indirectly estimating maternal mortality is still under development but shows promise for countries lacking alternative sources of data and good statistics. This work uses census or survey data to apply the method to rural villages in Gambia; Mapuche settlements in Cautin, Chile; marginal populations on the outskirts of Lima, Peru; and rural villages of Avaroa, Bolivia. The method is explained in detail following presentation of the results. The necessary basic information is outlined, and the particularities of its application to each Latin American case are discussed. The surviving sisters method was developed by Graham and Brass to derive indicators of maternal mortality based on the proportion of sisters who arrive at fertile age and die during pregnancy, delivery, or the postpartum period. The method transforms the proportions of sisters who died of maternal causes obtained from a census or survey into conventional probabilities of death. The basic information required concerns the numbers of sisters entering the reproductive period (excluding the respondent is she is a woman), the number surviving and decreased at the survey data, and the number who died during pregnancy, delivery, or the postpartum period. The probabilities of dying from a maternal cause were estimated on the basis of the sister survival method at 1/98 in Lima, 1/53 in Cautin, 1/17 in Gambia, and 1/10 in Bolivia. These probabilities correspond to ratios of maternal mortality per 100,000 live births of 286 in Lima, 414 in Cautin, 1005 in Gambia, and 1379 in Bolivia. The results demonstrate great variability in maternal mortality rates. In the cases of Lima and Cautin there were significant differences between estimates derived from the sister survival method and those derived from vital statistics. The 4 cases demonstrated the familiar association between maternal and infant mortality, fertility, and overall female mortality expressed in life expectancy at birth. The more detailed presentation of the 3 Latin American cases stresses the need to formulate survey questions that will enable the population at risk to be correctly identified in each case. A minimum of 3 questions is usually required, and their formulation may vary depending in part on the importance of extramarital fertility.


Objective To evaluate and analyze the clinical effect of comprehensive rehabilitation therapy after arthroscopic rotator cuff repair using suture-bridge technique for full-thickness rotator cuff tears.Methods Forty-one patients (20 males,21 females; mean age 52.2 years) with full-thickness rotator cuff tears were treated with arthroscopic rotator cuff repair using suture-bridge technique between June 2010 and January 2012 in our hospital.After arthroscopic rotator cuff repair,the patients were randomly assigned to a treatment group (21 patients) or a control group (20 patients).The treatment group received systematic rehabilitation therapy including rehabilitation education,physical modalities treatment and rehabilitative training additionally,while the control group only accepted the routine rehabilitation therapy including stretching and muscle strength training.The outcome was evaluated at 6 months after surgery,by employing visual analogae scale (VAS),the range of motion (ROM) testing of shoulder joint flexion and rotation,the rating scale of University of California at Los Angeles (UCLA),and the shoulder index of American shoulder and elbow surgeons (ASES).Results The mean follow-up period was 15.6 months (8-24 months).Prior to intervention,there was no significant difference in any parameter between the two groups (P > 0.05).Six months later,all scores of assessments changed:in treatment group VAS (1.7 ± 1.5),ROM [flexion (168.3±31.3)°,rotation (47.2±11.2)°],UCLA(30.7 ±4.13) and ASES (85.1 ±15.67); in control group VAS(3.8±2.2),ROM[flexion (121.2 ±53.6)°,rotation (32.9 ±14.9)°],UCLA(18.3 ±4.94) and ASES (36.4 ± 17.70).Significant changes occurred in both groups in all the parameters after treatment when compare to baseline (P < 0.05).Conclusions Comprehensive rehabilitation therapy is an effective approach for improving motor ability of the shoulder in patients after arthroscopic rotator cuff repair with suture-bridge technique for their full-thickness rotator cuff tears.

Key words:
Arthroscopy;  Rotator cuff;  Suture bridge technique;  Rehabilitation therapy


The evolution towards 5G consists of managing highly dynamic networks and making decisions related to the provisioning of networks in an as-a-service and cost-aware fashion. This is translated by 5G verticals that are dedicated to specific services, applications, or use cases fulfilling the constant demand of vertical industries. In this vein, to achieve the high-level goals defined by operators and service providers, and to answer to the elasticity and low-latency specifications of the upcoming 5G mobile system, the optimal placement of virtual network functions must cope with the non-uniform service demands and the irregular nature of network topologies. This paper addresses this issue by mapping the non-uniform distribution of signaling messages in the physical domain to a new uniform environment (i.e., canonical domain) whereby the placement of core functions is more feasible and efficient by means of Schwartz–Christoffel conformal mappings. The experimentation results, compared to some baseline approaches, have proven the efficiency of the conformal mapping based placement in allocating the virtual resources (i.e., virtual CPU and virtual storage) with regard to the optimal end-to-end delay, cost and activated virtual machines. Another interesting contribution is that all placement decisions are based on a realistic spatio-temporal user-centric model, which defines both the mobility of user equipments and the underlying service usage.


We propose an approach to the aggregation of risks which is based on estimation of simple quantities (such as covariances) associated to a vector of dependent random variables, and which avoids the use of parametric families of copulae. Our main result demonstrates that the method leads to bounds on the worst case Value at Risk for a sum of dependent random variables. Its proof applies duality theory for infinite dimensional linear programs.


INTRODUCTION The fuel cost is boosting day by day due to that world needs alternative fuel sources. So we need to develop an eco-friendly fuel to reduce the dependency of fossil fuels, because of increase of fuel demand due to the increase in Automobile industry, power plant, cooking purpose etc... Considering these reasons we found an alternative fuel one of the major energy media is oil the fuel production of oil is expected to reach peak next few years. The abundant supplies of coal also, so there is a need for an alternative fuel sources. Biodiesel will be a renewable source, clean and complete combustion; biodiesel developed by animal fat, vegetable oils and usedcooking oil. Biodiesel characteristics meet ASTM standards. Biodiesel and its blends to diesel can be used in diesel engine directly with no alterations of engine. Like that various vegetable oils are considered for the running CI engine in worldwide but Jatropha bio-diesel oil is most promising biodiesel among all these alternative fuel. The CI engines are mostly used due to its stable operation and its economic nature. The fast growth of population and consequent energy utilization leads to decreasing of conventional sources there is a need for renewable alternative fuel source. Due to the effect of greenhouse gas and the regulation to follow the norms of emission to safe guard the eco-system from pollution. Bio fuel is the replacing fuel for petroleum fuels. Biofuel obtained from vegetable oil is one of the renewable energy that can be used in a CI engine without any modifications. Other characteristics of biodiesel are same as of diesel. The present study reveals that bio-diesel from Artocarpus heterophyllus seed oil is suitable for alternative fuel to convert a Biofuel. Biodiesel is a substitute fuel just like a conventional or fossil diesel and a methyl ester of fatty acid derived by using a range of organic sources of oils; biodiesel also a renewable fuel, biodegradable and non-toxic. But it will be produced from animal fats, vegetable oil, sallow and left over cooking oil by using the process called Transesterification. R. Rezaei was done research various catalyst he used CaO as the suitable catalyst because it's miles cheaper and environmental friendly. Transesterification response changed into completed in presence of soybean oil, methanol and mussel shell catalyst at temperature 60°C using RSM technique. The result indicates that at most desirable situation the purity of the yield of produced biodiesel at calcination temperature 1050°C catalyst concentration of 12 wt. % and methanol to grease ratio of 24:1. In this condition the purity and yield of produced biodiesel is a hundred% and ninety four.1%. The result suggests that the catalyst re-calcination decreases the pastime of the catalyst.


A formula for calculating buckling strength of the two-end completely fixed cylindrical shell under axial compression and bending is presented, analysing the benefit of the stiffened cylindrical shell. The minimum weight design of ring stiffened cylindrical shells for cranes is given and a simple design programme for the shell is presented.


The binding of Cd( II) to human serum albumin (HSA) or bovine serum albumin (BSA) has been studied by equilibrium dialysis at physiological pH (7.43). The successive stability constants for the Cd( II ) - HSA and Cd ( II ) - BSA systems are determined for the first time by non - linear least - square method fitting Bjerrum formula, the order of magnitude of the K1 ~ K3 in both systems is found to be 104. The analyses of Hill coefficients and free energy coupling indicate that the strong positive cooperative effect exists in both Cd( II ) - HSA and Cd( II ) - BSA systems, and the positive cooperative effect in Cd( II ) - HSA system is much stronger than that in Cd( II) - BSA system. The Scatchard analysis indicates that there are three strong binding sites for Cd(II) in both HSA and BSA. The probable locations and (or) coordinated atoms of the sites are also suggested based on the results of Cd( II) competing with Cu( II ), Zn( II ) or Ca( II ) to bind to HSA or BSA.


(exp Indians, North American/ or exp Health Services, Indigenous/ or Metis.mp. or exp Medicine, Traditional/ or exp Shamanism/ or exp Ethnopharmacology/ or Indigenous* or Aboriginal* or Amerindian* or Autochtone* or Metis or First Nations or First Nation* or (traditional adj1 (medicine* or heal* or food* or health*)) or Urban Indian* or "on reserve" or "off reserve*" or country food* or residential school* or shaman* or medicine m?n or medicine wom?n or ((native* or Indian or Indians) adj2 (person or persons or man or woman or men or women or child* or youth or youths or population* or people* or band or bands)) or Montagnais or Maliseet or Naskapi* or Mi'kmaq or Micmac or Mic mac or Migmaw or Mig maw or Beothuk*) AND (((Fredrickton or Moncton or New Jersey) and (exp Canada/ or Canad*)) OR exp New Brunswick/ or New Brunswick* or Nouveau Brunswick or Big Hole Tract or Metepenagiag or Eel Ground First Nation or Buctouche or Esgenoopetitj or Burnt Church or Devon Reserve or St Mary's First Nation or Eel River Reserve or Eel River Bar or Fort Folly Indian Point Reserve or Indian Island First Nation or Indian Ranch Reserve or Kingsclear or St John River Valley Tribal Council or Oromocto or Pabineau or Pokemouche or Mawiw or (Red Bank adj2 Reserve) or Richibucto or St Basile or Madawaska or Soegao or Tabusintac or Tobique or Wolastoqiyik or Woodstock First Nation)


Within the framework of a manifestly gauge invariant exact renormalization group for $SU(N)$ Yang-Mills, we derive a simple expression for the expectation value of an arbitrary gauge invariant operator. We illustrate the use of this formula by computing the $\mathrm{O}({g}^{2})$ correction to the rectangular, Euclidean Wilson loop with sides $T\ensuremath{\gg}L$. The standard result is trivially obtained, directly in the continuum, for the first time without fixing the gauge. We comment on possible future applications of the formalism.


The utility model relates to a super high pressure underground pulse efflux booster which is used for a petroleum well. The utility model is mainly composed of a turbine, a splined shaft, a thrust bearing, a liquid inlet tray, a large and a small two pistons, and a large and a small two steel jackets, the interior of the utility model is provided with a two-pole low speed turbodrill, a rotor shaft is provided with the thrust bearing, the lower end of the rotor shaft is provided with the splined shaft which is connected with the liquid inlet tray, the liquid inlet tray is driven to rotate, the liquid inlet tray is provided with a liquid inlet hole, the large piston is provided with a hole which is corresponding to the hole on the liquid inlet tray, one pulse is completed when the two holes are mutually communicated once, the large and a small two pistons are rigidly connected, and can be moved from top to bottom along the shaft following the liquid inlet tray. The utility model has the advantages of simple structure, fluent passage, and convenient operation.


The utility model relates to the field of test equipment, in particular to a semiconductor chip test probe station, which comprises a probe station main body, a probe and dotting device and a microscope assembly, wherein the probe station main body comprises a base, a chip bearing table, a probe and dotting device mounting disk, and a microscope bracket, a moving mechanism is mounted on the base, the probe station main body further comprises a chip table moving handle, a chip table height handle and a chip table rotating hand wheel, the chip table moving handle is mounted on the right side of the base, and is connected with bearings on the chip bearing table, the chip table height handle and the chip table rotating hand wheel are arranged on the left side of the base, and the chip table height handle is connected with a bottom plate of the chip bearing table. The ascending and descending of the chip bearing table are controlled through rotating the chip table height handle, and the chip table rotating hand wheel is connected on the left-side bearing of the chip bearing table to control the rotation of the chip bearing table.


One of the first potential uses of ATM cell-switching is in large enterprise-wide private networks. ATM provides greater flexibility in the utilisation of network resources. The paper describes, firstly, an architecture and operational mode for large private ATM networks based upon virtual path connections. Secondly, it discusses various performance oriented traffic control mechanisms and thirdly, it presents results obtained to date relating to an investigation into the bandwidth allocation strategies and priority control algorithms. >


Sarcopenia is the drastic loss of skeletal muscle mass and strength during ageing. In order to better understand the molecular pathogenesis of age‐related muscle wasting, we have performed a DIGE analysis of young adult versus old rat skeletal muscle. Proteomic profiling revealed that out of 2493 separated 2‐D spots, 69 proteins exhibited a drastically changed expression. Age‐dependent alterations in protein abundance indicated dramatic changes in metabolism, contractile activity, myofibrillar remodelling and stress response. In contrast to decreased levels of pyruvate kinase (PK), enolase and phosphofructokinase, the mitochondrial ATP synthase, succinate dehydrogenase, malate dehydrogenase, isocitrate dehydrogenase and adenylate kinase (AK) were increased in senescent fibres. Higher expression levels of myoglobin and fatty acid binding‐protein indicated a shift to more aerobic‐oxidative metabolism in a slower‐twitching aged fibre population. The drastic increase in αB‐crystallin and myotilin demonstrated substantial filament remodelling during ageing. An immunoblotting survey of selected muscle proteins confirmed the pathobiochemical transition process in aged muscle metabolism. The proteomic analysis of aged muscle has identified a large cohort of new biomarkers of sarcopenia including opposite changes in PK and AK, which might be useful for the design of improved diagnostic procedures and/or therapeutic strategies to counteract ageing‐induced muscle degeneration.


The article evaluates the effectiveness of two new designed module‐integrated three‐dimensional (3D) printed spacers in enhancing wastewater ultrafiltration efficiencies using vibratory shear‐enhanced processing (VSEP). The study investigates the star‐shaped spacer filled module channel (star spacer) and the column‐shaped herringbone spacer filled module channel with the same position as the flow direction (column spacer) and with the opposite position as the flow direction (rev column spacer). It compares the VSEP module‐integrated spacers with membrane module vibration (module vibration) and empty membrane module channel (control) configurations. The results show that the module integration of the 3D printed spacers can greatly improve the specific, average, and constant permeate fluxes and can contribute to reducing the total, reversible and irreversible resistance values, and specific energy consumption of the ultrafiltration membrane separation experiments. Overall, this study provides valuable insights into improving the performance of wastewater ultrafiltration systems and fouling mitigation through the module integration of 3D printed spacers and membrane module vibration.


In the Revue de Laryngologie for March 5, 1916, we published an initial work on the important question of the parotid salivary fistulre, and we proposed immobilization or absolute repose of the jaws as the preferable treatment, the result of the experience acquired under the direction of Professor Moure, head of the Otorhinolaryngologic Section of the 18th Region. A new year has brought us new cases which, since all have been treated systematically in the same manner with success, urge us to return to our initial study for the review of maxillofacial prosthesis. We agree with Morestin in considering a salivary fistula present when a permanent abnormal orifice connects the passages for the saliva with the outside. • Relatively rare in times of ,peace, salivary fistulre are, on the other hand, quite frequent in times of war; history shows us that they have been from antiquity up to the present time a subject of constant study for the practitioner who is called upon to remedy them. Galen, ignorant of the existence of the parotid gland, had already observed that in wounds of the cheek a clear liquid was discharged which might well be saliva, and that is all. Fabricius, of Aquapendente, in an analogous case, tells us quite simply: "Whence it comes and whither it goes, surely I don't know."


April 14, 2016 visit by grade 11 International Baccalaureate students from Glenview Park Secondary School, Cambridge, Ontario. Please take a few moments to complete this three question survey on today's visit.


The sulfur–sulfur bond of α-disulfones is attacked by hydroxide ion in alcohol to yield sulfinate and sulfonate ion by a second-order reaction, first order in each of the reactants. With aromatic disulfones the ρ value of the Hammett equation is 0.2. The Arrhenius activation energy of the reaction of p-tolyl disulfone is 7.95 kcal/mole.


it is an important part of financial accounting and management to improve the management and effectiveness of research funding. Meanwhile, it is the guarantee for the continued and good development of research.This article analyzes the issues of the research funding management in some research institutions and proposes related suggestions.


The AS/AGU rat has a recessive single point mutation in the gene coding for the gamma isoform of protein kinase C (PKC-γ) resulting in a failure to release dopamine in the striatum and impaired movement including a staggering gait, difficulty in initiating movement and a slight whole body tremor. This study examined the levels tyrosine hydroxylase, ubiquitin and parkin in individual SNC cell bodies, there was no evidence of a reduction in tyrosine hydroxylase levels although levels of ubiquitin and parkin were elevated in the cytoplasm. The findings support the hypothesis that the initial bar to dopamine availability in the striatum is reduced release, with substantia nigra cell death being a later phenomenon.


In France, there are few texts on fieldwork that draw upon feminist theory, and in particular on the situated epistemology of the standpoint. By promoting a form of science pushing back against the active invisibilization of entire swathes of the social world, feminist theory questions the effects of scientific authority on the definition of scientific objectivity. Based on a practice, it also provides tools that allow for a concrete grasp of the power relationships that structure the fieldwork, both as a social relationship and as a protocol. This article intends to translate in methodological terms this little known theoretical tradition and to consider fieldwork as the outcome of a socially situated interest, characterized by its inscription in political solidarities, that tests these solidarities and aims at feeding them with its results.


Due to waveguide dispersion and array shape distortion, target's energy spreads in the vicinity of direction of arrival in spatial orientation spectrum. To solve this problem, a spatial spectrum estimation method using beam signal spectral decomposition is proposed. Utilizing correlation between signals which spread in multiple beams, beam signal spectrum is decomposed using singular value decomposition to achieve coherent signal accumulation. Maximum eigenvalue is extracted as output energy of the intermediate beam. Without the need of estimating array shape, output gain of spatial energy spectrum is increased.


volves around contradictory and deficient legal provisions for the care of the mentally ill presenting to A&E departments. We experience similar problems in Edinburgh where A&E nursing staff are resistant to sitting with psychiatric patients or participating in their care. A recent initiative to provide trained psychiatric nurses on-call with the duty psychia trist has had its funding stopped and there are safety concerns about unsupported psychiatrists attending A&E. Rather than displacing our concerns onto mental health legislation we need to challenge this further discrimination against mental illness. Psychiatric emergencies should be managed like any other medical emergency with skilled nursing available throughout a patient's stay in A&E and in transfer to a


This paper presents a simplified approach for the application of material efficiency metrics to linear and convergent synthesis plans encountered in organic synthesis courses. Computations are facilitated and automated using intuitively designed Microsoft Excel spreadsheets without invoking abstract mathematical formulas. The merits of this approach include (a) direct application of green chemistry principles to synthesis planning; (b) strongly linking green metrics calculations and synthesis strategy; (c) pinpoint identification of strengths and weaknesses of any synthesis plan's material efficiency performance using effective visual aids; (d) in-depth quantitative and qualitative critiquing of synthesis plan performance and strategy; and (e) giving opportunities to students to offer insightful suggestions to improve or "green up" published procedures based on their growing personal database of chemical reactions as they continue their education in chemistry. An extensive database of over 600 examples ta...


1. Market Reforms, Global Linkages, and (Dis)continuity in Post-Socialist China 2. "My First Big Urban Purchase": Mobile Technologies and Modern Subjectivity3. Navigating Mobile Networks of Sociality and Intimacy 4. Picturing the Self, Imagining the World 5. Mobile Communication and Labor Politics


Nitric oxide (NO), a gaseous signaling molecule generated by NO synthase (NOS), is enhanced by inflammatory stimuli [1]. The exhaled nitric oxide fraction (FeNO) has been proposed as a marker of airway inflammation and a guide for anti-inflammatory therapy in asthma [1]. However, a persistently high FeNO is occasionally observed despite inhaled corticosteroids (ICS) therapy [2-4]. Excessive NO synthesis is well documented in severe asthma [5,6]. Also, it is suggested that some proportion of individuals are truly steroid resistant, which is defined as no clinical improvement after treatment with systemic steroids [7]. However, few studies have provided detailed data regarding the variability of change in FeNO by administration of systemic steroids and its impact on asthma control and lung function in patients with severe asthma and persistently high FeNO.


The behavior of the norms and the so-called Widom factors of Chebyshev polynomials and weighted Chebyshev polynomials on subsets of the unit circle is studied. As subsets, compact subsets are taken that are symmetric with respect to the real line. Upper and lower bounds for the norms in terms of the norms of Chebyshev and weighted Chebyshev polynomials on a certain related subset of [ − 1 , 1] are established. In the case of two circular arcs symmetric with respect to the origin, asymptotics of the corresponding Widom factors are derived, as well as exact values of their supremum and infimum are established.


Interpretation system is a practical and applied research area.Interpretation system is the important method to visitor service and environmental and science education in the natural heritage site.The paper systematically summaries,compares and analyzes the research progress of interpretation system and the practice of natural heritage site,from the concept,basic theory,planning,function,audience,evaluation,facilities and media of interpretation system research as well as the relevant system,planning,facilities status of heritage site etc..In the basis,it puts forward the 7 aspects of natural heritage interpretation system research which should be strengthen in China,namely: 1)conducting multi-discipline collaborative research,setting up special research organization of interpretation system;2)constructing research framework of interpretation system;3)strengthening the research on interpretation system planning pattern;4)perfecting interpretation system evaluation research;5)deepening the audience research;6)exploring the research on interpretation process and methods between interpreters and tourists;7)strengthening the merging of interpretation system research and natural heritage site practice,especially the empirical research of interpretation system planning and construction.


"Good apple pies are a considerable part of our domestic happiness." ~ Jane Austen This guide provides quick access to quality resources relevant to Baking and Pastry Arts


Results: Radiological findings were found to be consistent with COVID-19 pneumonia in 52 (80%) of 65 cases examined with low-dose CT protocol and in 44 (88%) of 50 cases examined with standard-dose CT protocol. Mean effective dose values were 0.60 ± 0.05 mSv for the low-dose CT protocol and 4.10 ± 1.81 mSv for the standard-dose CT protocol, and a statistically significant difference was found. No statistically significant difference was found between the two groups in the incidence of characteristic COVID-19 lung lesions, which showed a peripheral distribution pattern, defined as round-shaped, multifocal groundglass opacities and/or patchy consolidations, and less frequently interlobular septal thickening, crazy-paving pattern, and reverse-halo sign. In most cases, involvement of both lungs (69.7%) and more frequent involvement in the lower lobes were found. Only one lobe involvement was detected in 27 (28.1%) of 96 cases.


Control device for a high-pressure cleaning device (2) with a high pressure pump (4) and at least one of the high-pressure pump via a high pressure line connectable spray device, preferably a spray gun (18), characterized in that the control device comprises: - At least one gun circuit (32), in / on the spray gun (18a-c) - At least one connected for determining the switching state of an on / off switch on the spray gun (18a-c) with the gun circuit evaluation circuit (24a-c), which is disposed on a high pressure manifold (15) or on the high pressure pump (4) and - Which is designed to, by at least one, preferably two, relay (RS1) to control switching valves (14a-c), thus releasing or shutting off the water supply to the spray gun (18a-c) - Said at least one gun circuit (32) is connected via a conductive connection in / on the high-pressure hose (20a-c) with the machine ground, in particular the high-pressure pump (4) and the on-off switch (S1) and at least one oscillator (O1, O2 ), by which the flow of current to the evaluation circuit (24a-c) a signal characteristic for identification of the switching state of the on / off switch ...


The aim of this study is to determine the influence of personality type as described by Jungian personality theory on marriage problems and to determine the usability of the Myers-Briggs Type Indicator to solve problems in the understanding and appreciating of individual personality differences. The research depicts the importance of self-awareness to maintain significant relationships. Self-awareness is conceptualised as an integral part of personality psychology. Accurate personality assessment is described as a means to gain accurate self-awareness. A literature study is done on personality theories to discover what role they play in marriage counselling. The question where does the personality theory of Jung fit into personality psychology and marriage counselling is answered. The Myers-Briggs Personality Type Indicator as an application of Jungian personality theory and an assessment technique to gain accurate self-awareness is discussed. A literature study of different marriage counselling approaches is presented and the focus of these approaches is discussed. None of these approaches used personality theory explicitly. A marriage counselling approach is developed which integrates the Myers-Briggs Type Indicator. The approach has five pillars: 1. Developing mutual trust 2. Recognizing and accepting individual differences 3. Giving and receiving feedback 4. Solving problems 5. Letting go of the past The research presents case studies, which confirm that the Myers-Briggs Type Indicator does help individuals and couples to become self-aware and develop awareness of the differences between their personality types. This self-awareness helps to rebuild marital relationships.


Reproduction of book The Banning of "Little Black Sambo" from the Toronto Public Schools, 1956, by Daniel Braithwaite, Toronto, Ontario, 1978.


In this contribution, we will discuss how the study of various fluctuation observables may be used to explore the phase diagram of the strong interaction. We will briefly summarize the present study of experimental and theoretical research in this area. We will then discuss various corrections and issues which need to be understood and applied for a meaningful comparison of experimental measurements with theoretical predictions.


Information service is the inevitable trend of library development.By analyzing the characteristics of information service and RSS technology, this paper maintains that RSS-based library information service system should be established to fully exert the function of information and to promote library development.


Based on "Nirvana",the author elaborated the unique insight in psychopathology of Chan.The psychopathological phenomenon of Chan is "be vexed".The causes of psychological problems are "ignorance","settle" and the three poisons.Furthermore,the model of five aggregates demonstrates the normal mental processes and how the psychological problems arose.


The properties of ZnO tetrapod and multipod structures were investigated using scanning electron microscopy, x-ray diffraction, photoluminescence (PL), and electron paramagnetic resonance (EPR) spectroscopy. While there is relationship between g=1.96 EPR and green PL in some of the samples, this is not the case for all the samples. Therefore, the commonly assumed transition between a singly charged oxygen vacancy and photoexcited hole [K. Vanheusden, C. H. Seager, W. L. Warren, D. R. Tallant, and J. A. Voigt, Appl. Phys. Lett. 68, 403 (1996)] does not explain the green emission in all ZnO samples. The green emission likely originates from surface defects.


The physical and electrical properties of graphene have motivated a significant amount research for various applications. Graphene is pure carbon in the form of a very thin, nearly transparent sheet, one atom thick. It is remarkably strong for its very low weight (100 times stronger than steel) and it conducts heat and electricity with great efficiency. In recent experiments, epitaxial graphene on SiC substrate proves to be the best channel material for FETs, which provides a semiconducting bandgap of 0.26ev. Epitaxial graphene on SiC exhibits a wider gap than other alternative options such as bilayer graphene. Lithography need not required and is performed in 2-D. A model is analyzed based on graphene on SiC which provides good performance of a nanoscale FET. The analyzed model provides the way to the design parameter space. Current can be modulated by four means of magnitude. An Ion/Ioff ratio of 50 and a subthreshold slope of 145mV/dec can be obtained with a supply voltage of 0.25 V which shows a significant progress toward solid- state integration of graphene electronics.


The hydrogen‐atom dipole polarizability α is obtained by a double perturbation expansion based on a Hartree–Fock H0. The expansion α = α0 + λα1 + λ2α2 + ···, where λ is the continuous parameter for the Hartree–Fock perturbing potential, is found to be extremely close to a geometric series with αi+1 / αi = 0.433 ± 0.002. Computation of α as α0[1 − (α1 / α0)]−1 gives 4.499a03 in excellent agreement with the exact value 92a03. The origin of this geometric character is examined and its applicability to some many‐electron polarizabilities is demonstrated empirically.


When individual responses in a biological assay show considerable variation associated with the values of a concomitant variate, covariance analysis may be used in order to adjust the mean responses and to improve the precision of the assay. Usually this is preferable to the choice of an adjustment which involves an arbitrary assumption about the effect of variations in the concomitant variate on the measured response. Published accounts of the process are open to certain theoretical objections, though they may be sufficiently exact for most practical purposes. The present paper describes a method of calculating the relative potency, and its precision, which may be a little more laborious, but which is in full accord with standard statistical practice. The computations are illustrated on data from a prolactin assay by the pigeon crop-gland technique, in which the final crop-gland weight showed a positive correlation with the body weight at the start of the assay. The results are compared with those obtained either from the unadjusted crop-gland weights or from these weights expressed as proportions of body weights. The covariance method leads to a more precise estimate of the potency of the test preparation than do either of the others; there is evidence, however, that the increase in precision will not necessarily be large unless the correlation between the response and the concomitant variate is very close. In a final section, the full statistical tests of assay validity in the covariance analysis are described; these are lengthy, and fortunately are required only when the validity is in considerable doubt. The methods of adjustment have been described in this paper with respect to an assay depending upon parallel regression lines of responses on the logarithms of doses. They may be adapted for use with 'slope-ratio' assays (Bliss, 1946; Finney, 1945; 1948; Wood & Finney, 1946), in which the regression of response on dose itself is linear. So far the need for adjusting for concomitant variation in these assays seems not to have arisen, and discussion of computational details may be postponed until the need is felt.


This study aims to describe the metacognitive abilities of students in the Entrepreneurship Study Program. The metacognitive ability of students described in the study is the metacognitive ability of students with high, medium, and low academic abilities to solve mathematical problems in students of the entrepreneurship study program. This research was conducted by applying the qualitative method. The informants in this study were the Head of the Study Program and 8 students who were taken using the Total Sampling technique. Data collection techniques used field notes, tests, interviews, and documentation. Data analysis was carried out using data reduction. The results showed (1) students who had high mathematical ability had very good mathematical problem solving abilities, (2) students who had moderate mathematical ability had good mathematical problem solving abilities, and (3) students who had low mathematical ability had sufficient mathematical problem solving.


Recently, system virtualization has been applied to consumer electronics (CE) such as smart mobile phones. Although multi-core processors have become a viable solution for complex applications of consumer electronics, the issue of utilizing multi-core resources in the virtualization layer has not been researched sufficiently. In this paper, we present a new hypervisor design and implementation for multi-core CE devices. We concretely describe virtualization methods for a multi-core processor and multi-core-related subsystems. We also analyze bottlenecks of network performance in a virtualization environment that supports multimedia applications and propose an efficient virtual interrupt distributor. Our new multi-core hypervisor improves network performance by 5.5 times as compared to a hypervisor without the virtual interrupt distributor.


During March 1995 a cross-sectional investigation of differences in motor competence indices and social behavior were completed. Two groups of adolescents with mental retardation were compared: SO – sportsmen included in the Special Olympics Sports Program and NON – nonsportsmen. The published results (Válková 1996) showed, in general, better results for SO subjects, although causality of the sport program influence could not be confirmed. This was the reason for a repeated measurement of the same participants in June 1997 after an ongoing sport program. First of all the repeated measurement documented that a two year period is sufficient enough for assimilation of the intervention variable (targeted sports program) for adolescents with mental retardation (MR). The results of the 95/97 comparative investigation presented different developmental trends between SO and NON groups. Decreasing trends in motor competence items and stabilized or slightly increasing trends of social behavior were found in the NON-group. A stabilized trend for motor competence items and increasing trends were found in social behavior in the SO-group.


English has become the 'lingua franca' of international business and management and is the preferred means of communication in intercultural and international encounters. In this paper it is shown that both the spread of the English language and the increasing dominance of a management discourse are based on a series of tacit assumptions and imbued with specific ideologies. When occurring together, they create a hegemonic field of forces which encourages the emergence of identities in line with neoliberal market economies. In order to 'break open' such tacit assumptions and ideologies, it is suggested that a critical management pedagogy needs to take a linguistic turn in order to instil in students a sense of agency, initiative and possibility as well as a sense of structure, context and constraint.


In the introduction to their volume, Massimi and Breitenbach observe that Kant's philosophy of natural science is a flourishing domain of scholarship, within which the notion of a law is absolutely critical. Kant and the Laws of Nature, which contains thirteen chapters from top-notch, international scholars on the title topic, is hence a text of transparent value to researchers working in this burgeoning area. The volume is not, however, parochially limited to technical readings of Kant's views on physics. It rather offers substantial treatment of some of the most pressing and knotted issues in Kant scholarship, more broadly. Chapters concern the unity of practical and theoretical reason, the positive role reason plays in the generation of knowledge, Kant's conception of causality and answer to Hume's causal scepticism, the theoretical grounding of natural laws in Kant's general metaphysical picture, Kant's legacy in the history of physics, organisms and teleology, and the unity of nature. While the commentator specializing in Kant's theoretical philosophy or his conception of natural science will find the most of interest and use in the volume, almost any Kant scholar will find something edifying, illuminating and stimulating in this excellent book. Notably, many of the chapters in the volume extend and elaborate their authors' general research programmes, particularly those of Paul Guyer, Hannah Ginsborg and Michael Friedman. These chapters do not merely repackage stale ideas, however. The (relative) novice may use these chapters as introductions to the classic interpretations of contemporary giants in the field, while the expert's understanding of the theories is enhanced by the extension and elaboration. I especially highlight Friedman's contribution in this regard, as it connects his interpretation of Kant's theory of physics with his work on neo-Kantian theories of science as well as his post-Kuhnian account of scientific change. Beyond augmenting the reader's understanding of Friedman's account of the Metaphysical Foundations of Natural Science (MFNS below), his chapter synthesizes the broad, Friedmanian corpus, to the scholar's benefit. In chapter 1, 'Kant on the Unity and Diversity of Laws', Eric Watkins develops a univocal, overarching conception of laws in Kant's system which comprehends a priori and empirical laws of nature; moral laws; juridical laws; regulative, logical laws of reason; and cosmological laws. All such laws book reviews


Objective
Recurrent Cushing disease (CD) is a rare complication that occurs in patients who have undergone bilateral adrenalectomy (BLA). We report a case of recurrent CD in a patient with Nelson syndrome and adrenalectomy due to remnant adrenal tissue, and a novel treatment strategy using stereotactic body radiation therapy (SBRT) to the adrenal glands.

Methods
We report a case of recurrent CD in a woman with Nelson syndrome and adrenalectomy and describe her clinical course and management. We also include a literature review of CD management and adrenal radiation.

Results
The patient had persistent pituitary CD despite pituitary surgery and radiosurgery and underwent BLA. She developed recurrent CD due to a remnant adrenal gland post adrenalectomy. She then underwent SBRT to both adrenal beds to treat the remnant adrenal tissue. Her serum cortisol dropped rapidly after adrenal radiation and she experienced minimal side effects. She has been in remission for over 2 years.

Conclusion
This is the first reported case of recurrent CD in a patient post adrenalectomy that was successfully treated with SBRT to the remnant adrenal tissue.


In April 2009 the Swedish Supreme Court recognized copyright protection for the Mini-Maglite® torch as "artware" without any requirement for a special expression level. The overall impression of the well known Mini-Maglite torch was held to be different from other similar torches.The Court held that it displayed a sufficient degree of independence and originality despite the fact that the functional design properties of the torch are neither new nor original. This article investigates the intersection between different IPR rules in Sweden and certain other European countries and the possible extent of the copyright legislation. It concludes that the Swedish position is untenable and that this demonstrates that there is a need for the European harmonization of substantive copyright legislation


Background Abbreviated magnetic resonance imaging (aMRI) protocols have emerged as an alternative to multiparametric MRI (mpMRI) to reduce examination time and costs. Purpose To compare multiple aMRI protocols for predicting pathological stage ≥T3 (≥pT3) prostate cancer (PCa). Material and Methods One hundred and eight men undergoing staging mpMRI before radical prostatectomy (RP) were retrospectively evaluated. 3.0-T imaging was performed with a 32-channel surface coil and a protocol including diffusion-weighted imaging (DWI), transverse T2-weighted (tT2W) imaging, coronal T2W (cT2W) imaging, sagittal T2W (sT2) imaging, and dynamic contrast-enhanced (DCE) imaging. Two readers independently assessed whether any MRI observation showed stage ≥T3 on each sequence (reading order: DWI, cT2W, tT2W, sT2W, DCE). Final stage was assessed by matching readers' assignments to pathology, and combining them into eight protocols: DWI + tT2W, DWI + cT2W + tT2W, DWI + tT2W + sT2W, DWI + cT2W + tT2W + sT2W, DWI + tT2W + DCE, DWI + cT2W + tT2W + DCE, DWI + tT2W + sT2W + DCE, and mpMRI. Diagnostic accuracy and inter-reader agreement for aMRI protocols were calculated. Results Prevalence of ≥pT3 PCa was 31.5%. Sensitivity, specificity, positive (PPV) and negative predictive value (NPV) of aMRI protocols were comparable to mpMRI for R1. Sensitivity was 74.3% (95% confidence interval [CI] 64.8–72.0) to 77.1% (95% CI 67.9–84.4), and NPV 86.8% (95% CI 78.6–92.3) to 88.1% (95% CI 80.1–93.3). All accuracy measures of the various aMRI protocols were similar to mpMRI also for R2, albeit all slightly lower compared to R1. On a per-protocol basis, there was substantial inter-reader agreement in predicting stage ≥pT3 (k 0.63–0.67). Conclusion When comparing the diagnostic accuracy of multiple aMRI protocols against mpMRI for predicting stage ≥pT3 PCa, the protocol with the fewest sequences (DWI + tT2W) is apparently equivalent to standard mpMRI.


A survey was undertaken in Cape Town South Africa in the early months of 1962 in an effort to determine to what extent the high birthrate and the size of the family affect the health of the individual preschool child as well as what other factors play a part. Families were compared with a control group on the basis of the state of nutrition of the preschool members taking 1 group where the children were underweight and a 2nd group where children had died from causes related to malnutrition. The effects of the high birthrate proverty environment and the capacity of the parents were considered. The survey was limited to black families. The size of the family appears to have little effect per se on the health of the younger family members; families are "at risk" because of poverty accompanied by poor parental capacity. The effect of education in limiting the size of families is clearly demonstrated. Mothers of the families "at risk" are usually the last to attend birth control clinics or to use the advice they are offered if they do attend. Improvement in the health of the child population is dependent upon improvement in the standard of living although temporary measures e.g. subsidized milk may work to prevent the worst levels of malnutrition. Isolated efforts to limit the population cannot have any marked effect on child health unless accompanied by improvement in education and standards of living.


Using the modern time series analysis method and white noise estimation theory, under the linear minimum variance optimal information fusion criterion, for multisensor systems with colored measurement noise, the multisensor optimal information fusion white noise deconvolution Wiener filter is presented, which consists of weighting local white noise deconvolution Wiener filters. The formula of computing covariances among the local filtering errors is presented, and the formula of optimal weighting coefficients is also given. Compared with the single sensor case, the accuracy of the fused filter is improved. It can be applied to signal processing in oil seismic exploration. A simulation example for information fusion Bernoulli-Gaussian white noise deconvolution filter shows its effectiveness


In the original mixture density network(MDN), which was introduced by Bishop and Nabney, the parameters of the conditional probability density function are represented by the output vector of a single multi-layer perceptron. Among the recent modification of the MDNs, there is the so-called modified mixture density network, in which each of the priors, conditional means, and covariances is represented via an independent multi-layer perceptron. In this paper, we consider a further simplification of the modified MDN, in which the conditional means are linear with respect to the input variable together with the development of the MATLAB program for the simplification. In this paper, we first briefly review the original mixture density network, then we also review the modified mixture density network in which independent multi-layer perceptrons play an important role in the learning for the parameters of the conditional probability, and finally present a further modification so that the conditional means are linear in the input. The applicability of the presented method is shown via an illustrative simulation example.


[Abstract] Activity-dependent local mRNA translation endows synapses to remodel their structure and function (Bramham and Wells, 2007). This process is tightly controlled by the state of phosphorylation of several components of the translational machinery including initiation factors and ribosomal proteins (Buffington et al. , 2014). The present protocol describes a method to prepare striatal synaptoneurosomes, from adult mice, containing both pre- and postsynaptic elements in which the level of synaptic phospho-proteins can be quantified (Biever et al. , 2015).


The poets of "Guilaizhe" and "Menglongshi" both take"the culture revolution" as the cultural re-source of their writing.Because of their difference experiences,believes,they use different manners in monody: direct monody and image lyricism.Differnt manners originate from the different cognition of the subjective and objective,and the further reason is the difference between the manner of thinking.


Iodine(III) chloride and free base para-substituted meso-tetraarylporphyrins (H 2 t(4-Xp)p, X = OCH 3 , CH 3 , CH(CH) 3 , H, Cl) react at mild conditions for formation of [(ICl 3 )H 2 t(4-Xp)p] molecular complexes. The very close correspondence between the UV-VIS and ( 1 H, 13 C) NMR spectra of these complexes and molecular complexes of porphyrins with various acceptors indicated that two lone pairs of the pyrrolenine nitrogens in the tilted porphyrin macrocycle bonded to an iodine(III) center of ICl 3 .


Mario Sims, PhD; Sharon B. Wyatt, PhD; Mary Lou Gutierrez, PhD; Herman A. Taylor, MD, MPH; David R. Williams, PhD, MPH Objective: Assessing the discrimination-health disparities hypothesis requires psychometrically sound, multidimensional measures of discrimination. Among the available discrimination measures, few are multidimensional and none have adequate psychometric testing in a large, African American sample. We report the development and psychometric testing of the multidimensional Jackson Heart Study Discrimination (JHSDIS) Instrument.


ABSTRACT While research on interstate rivalries is abundant, scholarship examining nonstate rivalries remains limited. To address this shortcoming, in this article we introduce the Armed Nonstate Actor Rivalry Dataset (ANARD) – a dataset which captures dyadic rivalries and militarised disputes among armed nonstate actors in the Middle East and North Africa (MENA) between 1993 and 2018. We begin by explaining why fine-grained data on militarised interactions between armed nonstate organisations are needed for a comprehensive understanding of conflict. We then provide details of the data collection process and coding practices. Finally, we identify the contributions that ANARD can make to conflict research.


Integration of viral DNA in the genome of host cells triggers host-pathogens interaction that are consequential for the virus and the infected cells. In cells semi-permissive for viral replication, the human herpesvirus 6B (HHV-6B) integrates its genome into the host telomeric sequences. Interestingly, HHV-6B integration in gametes leads to a condition called inherited chromosomally integrated HHV-6B (iciHHV-6B), where the newborn carries a copy of HHV-6B in every cell of its body and is associated with health issues such as spontaneous abortion rates, pre-eclampsia and angina pectoris when transmitted to its offspring. Unlike retroviruses, the mechanism that leads to viral integration of DNA viruses and the consequences of these events on host cells are not well characterized. Here, we report that HHV-6B infection induce genomic instability by suppressing the ability of the host cell to sense DNA double-strand break (DSB). We discovered that this phenotype is mediated by the ability of the immediate-early HHV-6B protein IE1 to bind, delocalize, and inhibit the functions of the DNA damage sensor NBS1. These results raise the possibility that the genomic instability induced by the expression of IE1 from integrated genomes contributes to the development of iciHHV-6B-associated disease. As reported for other types of viruses, the inhibition of DSB sensing and signaling promotes viral replication. However, HHV-6B integration is not affected when this pathway is inhibited, supporting models where integration of the viral genome at telomeric sequence is dictated by mechanisms that promote telomere-elongation in a given infected cell and not solely DNA repair mechanisms.


The article contains modern data on etiology, pathogenesis, manifestations and mechanisms of development of the most common forms of lipid metabolism disturbances in humans, such as obesity, emaciation, lipodystrophy, lipidosis, dyslipoproteinemia and atherosclerosis. The authors give the informative materials for self-testing and correction of the knowledge level.


In endometrial carcinoma patients, metastases to bones are rare and isolated metastases to extremities are extremely rare. We describe the case of a 59-year-old patient who underwent surgery followed by adjuvant radiotherapy due to endometrioid endometrial adenocarcinoma (grade 2, FIGO Stage II). After intervals of nine and 18 months respectively, she was diagnosed with metastatic tumours located in the right tibia and in the left humerus. The metastases were confirmed by biopsy. Following irradiation of metastatic lesions, the relief of symptoms was observed, and the patient remains under observation. We conclude that patients presenting a history of endometrial carcinoma with chronic pain in the extremities should be carefully evaluated, because although extremely rare, the carcinoma can metastasize to bones. Treatment of bone metastasis from endometrioid endometrial carcinoma by irradiation may increase quality of life and prolong survival.


A self-help organization of current and former mental patients brought an action challenging the constitutionality of voluntary, involuntary, and emergency commitment procedures under the New York Mental Hygiene Law. The Eastern District Court of New York ruled that the procedures comply with substantive due process even though they require neither a showing that the patient has engaged in a recent act manifesting imminent dangerousness nor a guarantee that commitment will afford the patient a realistic opportunity to improve or be cured. The federal court also found that the statute's failure to provide shorter time periods before judicial review, a privilege against self-incrimination, and stricter safeguards protecting the patient's right to refuse treatment did not amount to a violation of substantive due process.


We propose a novel distributed resource allocation scheme for the up-link of a cellular multi-carrier system based on the message passing (MP) algorithm. In the proposed approach each transmitter iteratively sends and receives information messages to/from the base station with the goal of achieving an optimal resource allocation strategy. The exchanged messages are the solution of small distributed allocation problems. To reduce the computational load, the MP problems at the terminals follow a dynamic programming formulation. The advantage of the proposed scheme is that it distributes the computational effort among all the transmitters in the cell and it does not require the presence of a central controller that takes all the decisions. Numerical results show that the proposed approach is an excellent solution to the resource allocation problem for cellular multi-carrier systems.


Photovoltaic (Pb,La)(Zr,Ti)O3 (PLZT) films in a layered structure of different crystallographic orientations are fabricated by optimized metalorganic deposition (MOD). Such films of (001) orientation exhibit a photovoltaic electrical power approximately 20 times higher than that of random films. The anisotropic optical properties of the oriented films, including dark conductivity, photoconductivity and photovoltaic tensors, are obtained quantitatively. These results show that the photovoltaic output current and power of the oriented films are highly improved to be comparable to those of semiconductors and suitable for application in the optical sensor of micro-electro-mechanical systems (MEMS).


Sunscreens are the most popular way of protection against sunburn. Other possible indications are reduction of the risks of extrinsic aging and skin cancer. Inorganic and organic filters are used. Organic filters, such as PABA derivatives, cinnamates, benzophenones, and octocrylene may possess the risk of unwanted adverse events such as photo-allergy or negative environmental impact. All sunscreens that are used according to the manufacturers advice will reduce vitamin-D synthesis (Bens, 2014). Benzophenones are common organic UV-filters of sunscreens. However, these compounds are unstable under UV exposure. The generation of reactive oxygen species reduces proliferation of human keratinocytes. Furthermore, photosensitized benzophenones enhanced irreversible DNA damage (Amar et al., 2018; Amar et al., 2015). Benzophenones penetrate intact skin. Concentrations could be measured in serum and urine. The impact on male reproductive system in young men seemed to be small considering semen parameters, but is measurable (Adoamnei et al., 2018). These compounds exert anti-androgenic and estrogenic activities (Maipas & Nicolopoulou-Stamati, 2015). The results suggest that benzophenones should be avoided in safe sunscreen practices. Oxybenzone—an organic UV-filter used in sunscreens—has specifically been linked to coral reef bleaching. Furthermore, UV-filters such as 4-methylbenzylidene camphor, oxybenzone, octocrylene, and octinoxate have been identified in various species of fish worldwide. This could have possible consequences for the food chain (Schneider & Lim, 2018). Octinoxate and 4-methylbenzylidene camphor exert anti-androgenic and estrogenic activities (Maipas & Nicolopoulou-Stamati, 2015). To improve efficacy and acceptance of inorganic filter-containing sunscreens, nanoparticles have been developed. The most commonly used in-organic filters are ZnO and TiO2. TiO2 nanoparticles produce hydroxyl radicals upon UVA exposure as determined by electron spin resonance spectroscopy. However, no phototoxicity was observed (Tang et al., 2018). Continuous exposition of female mice to TiO2 nanoparticles at doses of 2.5, 5, or 10 mg/kg via gavage instillation for 30 days resulted in premature ovarian failure (Hong & Wang, 2018). Concerning environmental impact, inorganic filters are no innocent bystanders. Results of a recent study demonstrated that uncoated ZnO induces a severe and fast coral bleaching by disturbing the symbiosis between coral and zooxanthellae and dinoflagellates. The compound also stimulates microbial enrichment in the seawater surrounding the corals in contrast to TiO2 (Corinaldesi et al., 2018). Nanoparticles of TiO2, however, are neurotoxic for mollusks and fish larvae (Guan et al., 2018; Li et al., 2018). Protection from potentially harmful UV-irradiation needs education, behavioral modifications, clothes and less harmful UV-filters for topical sunscreen application.


In order to effectively solve the control problems of the low permeability high gas seam group,to highly promote the application of the pillarless coal and gas simultaneous mining technology in low permeability seam group and to promote the continuous improvement of the mine safety situation,the paper in detail introduced the background of the key technology,the update innovation achievements and the project practice cases.From the gateway retained backfill method,gas pressure releasing and drainage and other aspects under the typical geological conditions,the paper analyzed the application status and development tendency of the technology.The results showed that the optimized backfill system and the gas drainage system from the design could release the automation of the backfill,the gas drainage maximization and the cost minimization and could promote the standardization and industrialization of the technology application.The continued improved and developed pillarless coal and gas simultaneous mining theory and technology could provide the scientific reliable technical access to the safety and high efficient mining in the low permeability and high gassy seam group.


This paper aims to study the performance of a solar-powered adsorption chiller with a novel composite adsorbent material (silica activated carbon/CaCl2) operating during some typical months in Hong Kong. Modeling is established to investigate the cooling performance of this adsorption chiller driven by flat-type solar collectors with three different configurations of glaze: 1) single glazed cover; 2) double glazed cover and 3) transparent insulation material (TIM) cover. The simulation results show that the higher the solar collector temperature is, the better the coefficient of performance (COP) and the specific cooling power (SCP) of the adsorption chiller are. It is suggested to select a double glazed collector with a small value of the lumped capacitance for this adsorption chiller. Seasonal effects are discussed in which the solar COP achieves its highest value during autumn. However, the cooling capacities in spring, summer and autumn are similar. All in all, this newly developed composite material as adsorbent used in the adsorption chiller could achieve a mean solar COP of 0.36 and SCP of 94W/kg on a typical summer day of operation.Copyright © 2013 by ASME


The present invention is mobile terminal access method for WLAN. The method includes: for ASU to exam the validity of STA certificate of access request and the requested AP certificate, for ASU or STA to exam the private key of the AP certificate, and for ASU or AP to exam the private key of STA certificate; for ASU and AP to calculate based on the created random data to obtain conversation cipher key and select one kind of communication data enciphering and deciphering conversation algorithm supported by both sides. The said method has safe access identifying mechanism, less data communication amount for the identifying process, and no repeated use of the certificate identifying result.


Investigations which have figured in the present understanding of hu man requirements for iron are reviewed. Those studies reviewed include those on iron balance and turnover intestinal urinary integumental and menstrual losses of iron iron reserves physiological factors affecting iron absorption factors affecting iron availability from plant animal and other sources iron supplementation practices the assessment of iron deficiency and hemoglobin levels factors affecting iron nutritional status such as environmental stress and exercise the iron requirements of infants premature infants full-term infants children aged 2-5 years 6-12 years and 13-18 years and the iron requirements of pregnant lactating and elderly women.


In [1] the authors considered finitely-valued modal logics with Kripke style semantics where both propositions and the accessibility relation are finitely-valued over a finite residuated lattice. Unfortunately, the necessity operator does not satisfy the normality axiom (K). In this paper we consider a different approach based on introducing a multimodal logic where the previous necessity operator is replaced with a family, parametrized by truth values different from zero, of necessity operators each one semantically defined using the crisp accessibility relation given by the corresponding cut of the finitely-valued original accessibility relation. This multimodal logic is somehow more appealing than the original modal one because axiom (K) holds for each necessity operator. Besides defining this multimodal logic, in this paper we axiomatize it, and we prove that if the starting residuated lattice is a finite BL chain then the modal language and the multimodal one have the same expressive power iff this algebra is an MV chain. Keywords— many-valued modal logic, fuzzy modal logic, Łukasiewicz modal logic, fuzzy logic.


DE-AC02-05C H11231). The SunShot Initiative is a national effort to drive down the cost of solar electricity and support solar adoption. SunShot aims to make solar energy a low cost electricity source for all Americans through research and development efforts in collaboration with public and private partners. Learn more at www.energy.gov/sunshot. The report and recommendations were the product of collaboration between LBNL and an extended team of subject-matter experts from the real estate, appraisal, and solar data industries. R E P O R T S U M M A R Y LBNL-1006628 – 1–


Object of the present invention is to provide a novel method of manufacturing the polymer containing reactive group give excellent in strength of a cured product, comprising a composition thereof. By having a carbon containing containing two or more in a terminal - carbon unsaturated bond in the polymer terminal structure (A) and / or having terminal polymeric structure containing two or more reactive silyl group in an end the composition of composition (B), and excellent in strength can be obtained a cured product.


We study the question of whether one can uniquely determine a scalar quasilinear conductivity in an anisotropic medium by making voltage and current measurements at the boundary. This paper is dedicated to the memory of Professor Victor Isakov, who has made enormous contribution to the theory of inverse problem.


Endoscopic ultrasonography (EUS) has been widely applied not only in gastrointestinal tract but also in pancreatobiliary diseases. One of the important fields is esophageal cancer staging. In the past, tranditional balloon-type echoprobe has been used to evaluate the stage of esophageal cancer,but with many limitations including inability to pass through stenosis and compression of mucosal lesions by balloon. With improvement of the equipment, thin ultrasonic probe has been applied in EUS examination. To evaluate its role in staging esophageal cancer, 147 cases with 164 sessions undergoing esophageal EUS with thin ultrasonic probe (Olympus, UM2R/3R) were assessed. Among them, 47 cases with 54 sessions were esophageal cancer. Echo beam could penetrate well in all patients except two cases with advanced cancer. In 29 stenotic tumors that panendoscope could not transverse, thin ultrasonic probe still could pass though them with complete scanning in 21(72%) of them. For 12 cases with operation, patients except two pathological correlation showed ultrasonic probe had 100%, 66%, 86% accuracy in T1, T2, T3 staging respectively. For N staging, sensitivity,specificity and accuracy were 83%, 83% and 83% respectively. Neither complications nor breakage of probe occurred during these examinations. These data indicated that thin ultrasonic probe is a new satisfactory method in staging of esophageal cancer.


In this paper boundary value problems of ordinary differential equations on infinite intervals are analysed. There is a theory for problems of this kind which requires the fundamental matrix of the system of differential equations to have certain decay properties near infinity. The aim of this paper is to establish a theory which holds under weaker assumptions. The analysis for linear problems is done by determining the fundamental matrix of the system of differential equations asymptotically. For inhomogeneous problems a suitable particular solution having a "nice" asymptotic behaviour is chosen and so global existence and uniqueness theorems are established in the linear case. The asymptotic behaviour of this solution follows immediately. Nonlinear problems are treated by using perturbation techniques meaning linearization near infinity and by using the methods for the linear case. Moreover, some problems from fluid dynamics and thermodynamics are dealt with and they illustrate the power of the asymptot...


116 Background: RO4987655 is an oral and selective inhibitor of MEK, a key enzyme of the MAPK signaling pathway. This was a phase I, non-randomized, open-label, dose-escalation study in Japanese patients (pts) with advanced solid tumors. Primary objectives were determination of maximum tolerated dose (MTD) based on dose-limiting toxicities (DLTs), safety evaluation and PK analysis. Secondary objectives were PD analysis and exploratory analysis of RO4987655's anti-tumor activity according to the RECIST 1.0 criteria. Methods: Patients received an oral single dose of RO4987655 (1, 2, 4, 5, and 6.5 mg) (Cycle 0) followed by continuous once daily dosing (QD, 1, 2, and 4 mg/day) then twice daily dosing (4, 5, and 6.5 mg BID, total daily dose: 8, 10 and 13 mg/day) in 28-day cycles. A 3 + 3 dose-escalation design was used. Blood samples for PK analysis were collected in Cycle 0 (Day 1, 2 and 3) and in Cycle 1 (Day 1, 8, 15 and 22). PD was evaluated by pERK inhibition in peripheral blood mononuclear cells (PBMCs) ...


Working from the premise that Cape Verde is a member of the Black Atlantic musical family whose styles flowed freely from port to port, this study has delved deeper into the styles and time frames that figured into the mix, verifying that periods of intense transatlantic port activity correspond to the emergence of new genres. Cape Verde's musical history might be viewed as a sandbar on the beach that is continually reshaped and born a new by waves of musical influences circling between the continents. The ideas of individual Cape Verdeans ultimately created the music, of course, and a comparative approach is not meant to lessen those musicians' importance, or detract from the beauty and perfection of Cape Verde's greatest treasure. The footprints of transatlantic connections in Cape Verdean musical styles can be found in its rhythms, instruments, vocabularies, scores, and ship route patterns. People create styles, and musical communication happens on the personal level - through sailors sharing a tune at sea, through encounters in harbor dancehalls, and through ideas brought back home. Generations of seafarers found safe harbor in Cape Verde, carrying music round and round the Atlantic, and this process is still shaping the local forms, although the travel is now by jet, and the exchanges are often over the worldwide web. While some details about musical communities on the high seas may be lost to us, there is still information to be gained about Cape Verdean musical forms through a study of the multi-directional movements of musicians, artifacts, repertoires, and ideas around the Atlantic rim.


Abstract Some passenger cars with sunroofs open at tilted positions experience reverse flows into cabin rooms and wind noises much louder than in other cars. In this study, flows around an open tilted sunroof are numerically studied with varying body leakage. The effects of body leakage on ventilation and wind noise of a sunroof are examined, in particular. Furthermore, flow visualization, pressure and wind noise measured from the wind tunnel and road tests are presented. The results show that too small a body leakage results in poor ventilation performance and generates high wind noises around a sunroof. It is therefore very important to secure an adequate body leakage from the early design stage to achieve better performance of a sunroof as well as passengers' thermal comfort.


The paper introduces the application of information geometry to describe the ground states of Ising models by utilizing parity-check matrices of cyclic and quasi-cyclic codes on toric and spherical topologies. The approach establishes a connection between machine learning and error-correcting coding. This proposed approach has implications for the development of new embedding methods based on trapping sets. Statistical physics and number geometry applied for optimize error-correcting codes, leading to these embedding and sparse factorization methods. The paper establishes a direct connection between DNN architecture and error-correcting coding by demonstrating how state-of-the-art architectures (ChordMixer, Mega, Mega-chunk, CDIL, ...) from the long-range arena can be equivalent to of block and convolutional LDPC codes (Cage-graph, Repeat Accumulate). QC codes correspond to certain types of chemical elements, with the carbon element being represented by the mixed automorphism Shu-Lin-Fossorier QC-LDPC code. The connections between Belief Propagation and the Permanent, Bethe-Permanent, Nishimori Temperature, and Bethe-Hessian Matrix are elaborated upon in detail. The Quantum Approximate Optimization Algorithm (QAOA) used in the Sherrington-Kirkpatrick Ising model can be seen as analogous to the back-propagation loss function landscape in training DNNs. This similarity creates a comparable problem with TS pseudo-codeword, resembling the belief propagation method. Additionally, the layer depth in QAOA correlates to the number of decoding belief propagation iterations in the Wiberg decoding tree. Overall, this work has the potential to advance multiple fields, from Information Theory, DNN architecture design (sparse and structured prior graph topology), efficient hardware design for Quantum and Classical DPU/TPU (graph, quantize and shift register architect.) to Materials Science and beyond.


We present a new cache-efficient parallel multilayer Gauss-Seidel algorithm to solve 2D diffusion equations on distributed memory machines, by focusing on improving its cache behaviour and parallelism simultaneously. The novelty of our parallel multi-layer algorithm lies in performing Gauss- Seidel in two alternating sweeping directions (with multiple layers, i.e., iterations per direction) and applying alternating tiling strategies in two opposite sweeping directions to the subdomain allocated to every processor. As a result, its efficiency comes from a significant reduction in two sources of overhead: data cache misses and communication costs. In comparison with two commonly used parallel Gauss-Seidel algorithms, our algorithm has good performance and scalability in a cluster computing environment.


In his "Critique of Bertram," which appeared first in the Courier (September 1816) and then in the Biographia Literaria (1817), Coleridge draws what proves to be a crucial analogy between political and theatrical management. Hailing Samuel Whitbread's proposal to reform the theater by limiting the size of the governing body of Drury Lane, Coleridge applies this wisdom to contemporary political affairs and suggests that in both cases "the right of suffrage may be too widely diffused."' Although the explicit analogy was dropped when the "Critique" was inserted in the Biographia, it nonetheless informs Coleridge's views of drama and the contemporary stage. For Coleridge in his dramatic discussions consistently navigates between what he calls the body politic and body theatric. To assert a crucial connection between politics and drama in Coleridge immediately invites two objections. The first sees Coleridge's residence in a "Kantean hazeworld" as precluding any significant engagements with the political affairs of his times. Although still common, such an objection has been substantially countered by recent critical work and the editorial focus of the Princeton edition of his collected works.2 A second objection takes Coleridge's position as a romantic poet to imply both a lack of talent and a lack of interest in drama and the contemporary stage. This implication has been challenged much less frequently than the first, since it arises out of an entrenched view of romantic drama overall.3 Because we are in the habit of viewing the plays produced by romantic poets as artistic failures, we neglect to take seriously the seriousness with which these poets wrote and theorized about drama. Worse, we overlook the degree to which their conception of drama works against the compartmentalizing of aesthetic and political concerns. In particular, Coleridge not only began his career as a playwright and earned more from his plays than from any other literary endeavor, he also wrote his plays and drama criticism expressly to reform the stage and contemporary playgoers' states of mind.


Abstract Stilbenes are abundant in the heartwood of Scots pine (Pinus sylvestris L.) and are known to have strong antifungal efficiency. In this study, Scots pine sapwood blocks were impregnated with crude heartwood extract containing the stilbenes pinosylvin (PS) and the pinosylvin monomethyl ether (PSM). Impregnated blocks were submitted to brown-rot fungi, Coniophora puteana, Gloeophyllum trabeum, and Rhodonia (Poria) placenta, and fungal growth test and decay test were performed. Both tests showed that the impregnation with a high concentration of stilbenes (60 mg g-1 dry wood) significantly suppressed the growth of fungi and slowed down the decay process of wood blocks, especially in case of G. trabeum. However, chemical analysis showed that PS and PSM were degraded by all the three types of fungi, obviously via modification to resveratrol and methylresveratrol. Rhodonia placenta displayed the fastest rate of degradation. Thus, impregnation with biodegradable stilbenes could be a viable alternative for wood preservation only in service situations with low or transient risk of decay.


In recent years, zoos pay more attention to animal welfare. The welfare of captive animals has therefore been the subject of many studies. These include habitat-enrichmentas well as feeding-enrichment strategies. This study is about another possibility to reduce stress: limiting the perception by lions and tigers of the human public. This was done with a Natural fence. Lions were found to stand still in their enclosure for a significantly longer period of time while this Natural Fence was partly removed. For the tigers, three behavior types turned out to be significantly different across the three phases tested. Also, cortisol levels were determined using hair samples. For each of the animals tested, cortisol levels were higher when part of the fence was removed, compared to baseline levels, although this difference was not significant.


The wear characteristics and wear mechanisms of plasma sprayed Al 2O 3 40%TiO 2 and Cr 2O 3 coatings on casting aluminum alloy (AC4C) were investigated. The bonding strength between the substrate and the coating was measured by scratch tester. The profile of worn coating surface and microstructure of the coatings were observed with SEM. The wear mechanism is discussed as well. The experimental results indicate that the wear resistance of Cr 2O 3 coating is greater than that of Al 2O 3 40%TiO 2 coating. The friction coefficient of Cr 2O 3 coating in sliding against SiC ceramic ball is lower than that of Al 2O 3 40%TiO 2 coating against the same counterface. It has also been found that the bonding strength, voids and porosities of the coating surface govern the friction and wear properties of the coatings. The wear mechanism of Al 2O 3 40%TiO 2 coating is mainly plastic deformation and delamination, whereas that of Cr 2O 3 coating is abrasive wear.


This paper discusses an integrated transport study conducted for part of the Ring Road in Nottingham, U.K. The steps taken to assess public transport options are described, including conventional bus priority and guided bus. Interchange proposals were at the forefront of this integrated approach. After the preferred option was selected, a series of assessments were carried out that were weighed against local, regional, and government objectives. A current summary of further work is provided that assesses the merits of busways vs. guided buses.