The present invention provides a flash memory cell and a flash memory device. The flash memory cell includes: a substrate; a first dielectric layer located on the substrate; a floating gate layer located on the first dielectric layer and having a plurality of floating gates; isolation layers between adjacent floating gates in the plurality of floating gates; a second dielectric layer located on the floating gate layer; a control gate layer located on a three-layer stacked structure composed of the first dielectric layer/the floating gate layer/the second dielectric layer; an outer dielectric layer coating a four-layer stacked structure composed of the first dielectric layer/the floating gate layer/ the second dielectric layer/the control gate layer; and a source region and a drain region which are arranged at two sides of the three-layer stacked structure. According to the invention, the ability of the flash memory cell to resist the single event effects is improved, and the flash memory cell and the flash memory device are applicable in the memory radiation-proof and reinforcement field and the storage field.


Nonresponse is a common issue affecting the vast majority of surveys. Efforts to convince those unwilling to participate in a survey might not necessary result in a better picture of the target population and can lead to higher, not lower, nonresponse bias. We investigate the impact of non-response in the European Commission & European Central Bank Survey on the Access to Finance of Enterprises (SAFE), which collects evidence on the financing conditions faced by European SMEs compared with those of large firms. This survey, conducted by telephone bi-annually since 2009 by the ECB and the European Commission, provides a valuable means to search for this kind of bias, given the high heterogeneity of response propensities across countries. The study relies on so-called "Representativity Indicators" developed within the Representativity Indicators of Survey Quality (RISQ) project, which measure the distance to a fully representative response. On this basis, we examine the quality of the SAFE Survey at different stages of the fieldwork as well as across different survey waves and countries. The RISQ methodology relies on rich sampling frame information, which is however partly limited in the case of the SAFE. We also assess the representativeness of the SAFE particular subsample created by linking the survey responses with the companies' financial information from a business register; this sub-sampling is another potential source of bias which we also attempt to quantify. Finally, we suggest possible ways how to improve monitoring of the possible nonresponse bias in the future rounds of the survey.


The percentage of soil pore space filled with water (percent water-filled pores, % WFP), as determined by water content and total porosity, appears to be closely related to soil microbial activity under different tillage regimes. Soil incubated in the laboratory at 60% WFP supported maximum aerobic microbial activity as determined by CO production and O uptake. In the field, % WFP of surface no-tillage soils (0–75 mm) at four U.S. locations averaged 62% at time of sampling, whereas that for plowed soils was 44%. This difference in % WFP was reflected in 3.4 and 9.4 times greater CO and NO production, respectively, from surface no-tillage soils over a 24-h period as compared to plowed soils. At a depth of 75 to 150 mm, % WFP values increased in both no-tillage and plowed soils, averaging approximately 70% for no tillage compared with 50 to 60% for plowed soils. Production of CO in the plowed soils was enhanced by the increased % WFP, resulting in little or no difference in CO production between tillage treatments. Nitrous oxide production, however, remained greater under no-tillage conditions. Substantially greater amounts of NO were produced from the N-fertilized soils, regardless of tillage practice. Production of CO and NO was primarily related to the % WFP of tillage treatments although, in several instances, soil-water-soluble C and NO levels were important as well. Calculations of relative aerobic microbial activity between no-tillage and plowed soils, based on differences in % WFP relative to maximum activity at 60%, indicated linear relationships for CO and NO production between WFP values of 30 to 70%. Below 60% WFP, water limits microbial activity, but above 60%, aerobic microbial activity decreases—apparently the result of reduced aeration.


The diagnosis of chronic, low-level exposure to carbon monoxide (CO) remains an enduring challenge for physicians worldwide.1,2 A colourless, odourless, and tasteless gas, CO is undetectable by exposed individuals.3 At the same time, as a product of incomplete combustion of carbon containing compounds, it may be readily produced in domestic settings where fossil fuels (coal, oil, gas) and wood are used.3

The UK Department of Health (DoH) …


This article sets out an argument for paying greater sociological attention to the public relations industry as an important mechanism through which society and culture are formed. It offers a theoretical and empirical exploration of public relations practice which begins to address this lacuna, using a Bourdieuian framework. After introducing the public relations industry and cultural intermediation, arguments are made for the centrality of discursive struggle in Bourdieu's work, drawing on other theorists as necessary to make explicit the logic that puts language and discourse at the centre of the struggle for symbolic power. This clarifies the importance of public relations as an object of sociological analysis. Bourdieu's conception of practice is then reflected on and applied to public relations, before the findings from an exploratory case study are considered. The article concludes by reviewing implications for future theoretical and empirical work in this area.


Abstract:In his sermon—"Miracles no Remedy for Unbelief" (2 May 1830)—Newman warned his audience that the lack of miracles often serves as an excuse for the true cause of unbelief: hardening the heart against the grace of God. What his audience presumably did not know was that Newman's sermon reiterated an extended disagreement with his brother, Charles Robert Newman. Both the sermon and the sibling struggle over faith versus unbelief still provide enduring lessons for contemporary readers.


The quadratic traveling salesman problem asks for a tour of minimal total costs where the costs are associated with each of two arcs that are traversed in succession. This structure arises, e.g., if the succession of two arcs represents loading processes in transport networks or a switch between different technologies in communication networks. Based on an integer program with quadratic objective function we present a linearized integer programming formulation and study the corresponding polyhedral structure of the asymmetric quadratic traveling salesman problem (AQTSP), where the costs may depend on the direction of traversal. The constructive approach that is used to establish the dimension of the underlying polytope allows us to prove the facetness of several classes of valid inequalities. Some of them are related to the Boolean quadric polytope. Two new classes are developed that exclude conflicting configurations. Among these the first one is separable in polynomial time, and the separation problem f...


Glutathione transferase omega-1 (GSTO1-1) is an enzyme which has been found to be involved in the activation of NLRP3 inflammasome, and GSTO1-1 inhibitors can serve as potential therapeutics of various inflammatory conditions. This thesis develops novel potent GSTO1-1 inhibitors, and describes the endeavour of improving the sensitivity of currently-used biochemical assay for the evaluation of GSTO1-1 inhibitors.


It is very important for weapon systems to manage the logistic support for the better combat readiness. Therefore, in this paper we review the issues of logistic support and suggest alternatives to effectively manage the logistic support for weapon systems by using performance based logistics, especially during operations and support phase.


Twenty chalazia were treated with intralesional triamcinolone acetonide injections. The diameter of 9 of the chalazia was < 6 mm. Eight of them were cured after a single injection and 1 after 2 injections. The diameter of 11 of the chalazia was ≧ 6 mm. Four cases responded to 1 injection and 5 to 2 injections. Two were operated on. Six patients had a recurrence 3–6 months later and were operated on. Corticosteroid injection is a serviceable alternative to surgery in the treatment of small chalazia. The indications are discussed.


able that an aorist participle was sometimes used in New Testament times of action that is not prior to that of the main verb but coincident with it or even subsequent to it. Such a participle (aanaaaflBvOl) is rendered literally "having saluted" at Acts 25: 13 in the American Standard Version margin, but "and saluted" in American Standard Version text, and "to welcome" in the present version. So "and he commanded" (xBABvaa~) in both versions of Acts 23 : 35. While an intimate feeling for the language makes a translator eager to distinguish the finer shades of meaning. and-what is not always possible-to express them, it also shows him that some distinctions are unimportant or unreal. and that a word-for-word rendering sometimes actually misrepresents the impression of the original. Thus the introductory Semitic expressions "and it came to pass that" and "answering said" need not be always literally retained, nor need the initial "and" of narrative sentences. It is obvious that the same word (xa{j, usually translated "also", is sometimes what the grammarians call pleonastic when it occurs after "with" (Phil. 4: 3) or "as" (e.g., 2 Peter 1 : 14, Heb. 4: 2) or "whom" (e.g., Luke 6: 13,14) or "which" (e.q., 1 Peter 3 : 21 ). In English it is best omitted in such cases. Today's better understanding of the Greek often produces a somewhat less subtle attitude to the translator's task. He cannot reproduce every vernacular touch of the original. nor the special and varied styles of the New Testament writers. For example, the defiance of Greek grammar which in the Book of Revelation seems to follow a pattern of its own does not show even in the more literal versions, yet the translator can quite conscientiously attempt an English that is as contemporary to himself as the Greek is now recognized to have been contemporary to the first Christian authors. As they wrote with neither grammatical precision nor absolute verbal consistency, he is willing to deal somewhat less meticulously with the data of a simple style that was naturally not too particular about modes of expression or conscious of some of the subtleties which some later interpreters read into it. To this he adds whatever he may modestly claim to have achieved of real insight into the meaning of the original. This contribution ought to be made available to English readers in a straightforward text, for in the Bible it has an importance out of proportion to its limited extent.


Inflammation characterises chronic asthma. The treatment, usually with inhaled glucocorticosteroids, aims to control inflammation. Bronchodilators are used only when necessary.
In an acute asthma attack, treatment is aimed at providing oxygen and relieving airflow obstruction with bronchodilators as quickly as possible. Glucocorticosteroids are given early in treatment, but they take time to have a clinical effect.


The invention discloses and provides a roasting sagger for a circulating type lithium battery anode material, which is simple in manufacturing process and structure, does not easily react with a lithium battery material, can avoid polluting the lithium battery material, does not pollute the environment and can be recycled, and a preparation method thereof. The preparation method of the roasting sagger for the circulating type lithium battery anode material comprises the following steps of: (1) uniformly mixing mullite, cordierite, aluminum oxide, corundum, kaolin, active magnesium oxide, spodumene and a bonding agent; adding the materials into a metal mould according to the weight; and pressing and molding a blank by pressing and molding equipment; (2) uniformly mixing zirconium oxide, the spodumene, cerium oxide, the corundum and the bonding agent; uniformly distributing the materials on the surface of the blank by a material distribution machine or manpower and pressing again by the pressing and molding equipment to obtain a semi-finished sagger product; and (3) drying the sagger semi-finished product and sintering. The roasting sagger disclosed by the invention can be widely applied to the field of the sagger for the lithium battery anode material.


Operations management techniques can benefit from integration of control theory methods when dealing with production and supply chain networks dynamics. In this context, we revisit a bond-graph based mathematical model that is able to capture the dynamics of multi-workstation production systems, and propose a state feedback control design to maintain work in process at desired levels. The closed loop performance of this real case inspired model was explored and simulations with the introduction of a disturbance in the production system were carried out. The proposed control design results in a disturbance-oriented behaviour that has advantages over pure push or pull systems commonly used in Production Planning and Control (PPC). In the given case, the results revealed that the model can provide prescriptive capacity adjustments and can help to define appropriate reference levels for the work in process in dynamic production environments.


Purpose The literature on feedback in clinical medical education has predominantly treated trainees as passive recipients. Past research has focused on how clinical supervisors can use feedback to improve a trainee's performance. On the basis of research in social and organizational psychology, the authors reconceptualized residents as active seekers of feedback. They investigated what individual and situational variables influence residents' feedback-seeking behavior on night shifts. Method Early in 2008, the authors sent obstetrics–gynecology residents in the Netherlands—both those in their first two years of graduate training and those gaining experience between undergraduate and graduate training—a questionnaire that assessed four predictor variables (learning and performance goal orientation, and instrumental and supportive leadership), two mediator variables (perceived feedback benefits and costs), and two outcome variables (frequency of feedback inquiry and monitoring). They used structural equation modeling software to test a hypothesized model of relationships between variables. Results The response rate was 76.5%. Results showed that residents who perceive more feedback benefits report a higher frequency of feedback inquiry and monitoring. More perceived feedback costs result mainly in more feedback monitoring. Residents with a higher learning goal orientation perceive more feedback benefits and fewer costs. Residents with a higher performance goal orientation perceive more feedback costs. Supportive physicians lead residents to perceive more feedback benefits and fewer costs. Conclusions This study showed that some residents actively seek feedback. Residents' feedback-seeking behavior partially depends on attending physicians' supervisory style. Residents' goal orientations influence their perceptions of the benefits and costs of feedback-seeking.


At a meeting on 9 August 2016 in St Petersburg, Russian President Vladimir Putin and his Turkish counterpart Recep Tayyip Erdogan vowed to boost cooperation, following a significant cooling of relations. This has put the Turkish Stream gas pipeline back on the agenda. However, despite the political rapprochement between Moscow and Ankara, an increasingly complicated regional geopolitical environment should be taken into consideration in assessing the prospects for this project, says Marco Giuli. In this Commentary, he argues that Turkish Stream might go against Turkish ambitions of becoming a regional gas hub, and that the EU should capitalise on this in order to limit an undesirable growth of Turkey's energy dependence on Russia.


This paper continues the series of contributions to APT concerning gender and mental health ( [Bartlett & Hassell, 2001][1] ; [Cremona & Etchegoyen, 2001][2] ; [Kennedy, 2001][3] ; [Kohen, 2001][4] ; [Kohen & Arnold, 2001][5] ; [Ramsay et al, 2001][6] ).

The need for specific psychiatric services


This issue includes a landmark study focused on the return on investment (ROI) from a worksitebased health management program (HMP) conducted at Citibank. Why is this article so important? Business leaders have continually challenged our industry to produce "bottom line" savings.~,2 Part of the problem is ours. We have developed programs on the premise that they not only improve worker health but that they also produce health care, absenteeism, and productivity savings that far outweigh program costs. This search for the "Holy Grail" in health promotion evaluations--i.e., documenting ROI savings--has been difficult if not impossible to attain. We have all long awaited credible ROI outcomes that could quantify cost savings using state-of-the-art research methods that economists would accept. Thins has been the 20+-year challenge for our industry. Now, r~he ROI analysis performed for Citibank utilizes some of the most sophisticated analytic methods developed by health economists. Actually, the genesis for this study came from the bank's management, who challenged the corporate medical director to produce ROI results--which is how the value of every other investment at Citibank is judged. For the study, the MEDSTAT group was hired because of its experience in performing and publishing high level research that passes the scrutiny of both economists and research scientists. This landmark study, concluded in 1998, was presented to Citibank management with an overall conclusion that the ].JMP produced impressive


Many World-Wide Web clients today are connected to the Internet via low-speed computer links. Examples are home users accessing the Internet through telephone lines, and wireless computer users. This form of communication is characterized by a client being attached to a high-bandwidth network through a poor link. This thesis examines techniques that can help bring Web performance for such poorlyconnected clients more in line with others that are well-connected. A prefetching scheme that is realized at a proxy server one network hop away from the client is proposed. The client does not need to be aware that prefetching is being performed; it is only aware of a perceived reduction in latency. The prefetching scheme considered takes full advantage of characteristics unique to the World-Wide Web, and it adapts dynamically to changing user behavior. A wireless network is emulated and used to help validate the ideas presented.


A method of simulation of the performance of jet engines, with the possibility of adapting to engine particularities, is presented. It employs an adaptation procedure coupled to a performance model solving the component matching problem. The proposed method can provide accurate simulation for engines of the same type, with differences that are due to manufacturing or assembly tolerances. It does not require accurate component maps, because they are derived during the adaptation procedure. It can also be used for health monitoring purposes, for component fault identification, and condition assessment. The effectiveness of the proposed method is demonstrated by application to two commercial jet engines.


Optically active 4-substituted pyrrolidin-2-one substructures can be found in various biologically active compounds such as CS-834, 1, an oral carbapenem antibiotic drug, rolipram, 2, an antidepressant agent and oxiracetame, 3, a nootropic drug for the Alzheimer's disease. Chiral 4hydroxypyrrolidin-2-one and its N-substituted derivatives are versatile intermediates for the synthesis of those compounds. Therefore, several methods for the synthesis of optically active 4-hydroxypyrrolidin-2-one derivatives have been developed including methods using enzymatic reaction and multistep synthsis from a chiral natural intermediate. 7-12


Objective To investigate the distribution and the antibiotic resistance in clinical isolates of Haemophilus influenzae for guiding antibiotic practice.Methods 134 clinical isolates of Haemophilus influenzae were collected from Tongji hospital in 2009.Antimicrobial susceptibility was tested by Kirby-Bauer method.The results were analyzed on the basis of CLSI 2008 M100-S18.Beta-lactamases were detected by nitrocefin disk.Results 134 clinical isolates of Haemophilus influenzae were mainly collected from the departments of out-pa-tient,pediatrics and respiratory.90% of strains were isolated from respiratory tract specimens.Susceptibility rate of Haemophilus influenzae to TMP/SMZ was the lowest,only 29.6%,and that to ampicillin was as low as 60%,while up to 85% of Haemophilus influenza were susceptible to cefuroxime,cefotaxime,azithromycin,ciprofloxacin and levofloxacin.Compared with those isolates from children,Haemophilus influenza coming from adults were more susceptible to ampicillin,ampicillin/sulbatan and TMP/SMZ.But those isolates from children were more sensitive to quinolone and azithromycin than adults isolates.The prevalence of beta-lactamase of all strains was 29.3%.46.2% of the isolates from children produced beta-lactamase,and with 15.5% from adults.Conclusions The isolates are mainly from respiratory specimens.It shows sensitive to the majority of antibiotics,but more than 70% strains were non-sensitive to trimethoprim-sulfamethoxazole.Trimethoprim-sulfamethoxazole is unsuitable to treat infections caused by Haemophilus influenzae for experiential therapy.


In the signal processing of digital still cameras more and more complex algorithms take place to reduce the noise in the images. In this thesis the in uence of the noise reduction on spatial resolution is analyzed and a measurement system is set up.


Abstract There were implemented samples of asymmetric Hopfield neural networks which have finite time of transition from one state to another. It was shown that in such systems, various oscillation modes could occur. It was revealed that the oscillation of the output signal of certain neuron could be treated as extra logical variable, which describes the state of the neuron. Asymmetric Hopfield neural networks are described in terms of ternary logic. Such logic may be employed in image recognition procedure.


Objective
To investigate the clinical efficacy of one-stage repairing the wounds after excision of soft tissue malignant tumor in lower limb with deep inferior epigastric perforator (DIEP) flaps.

Methods
From August, 2016 to July, 2018, 11 patients(8 males and 3 females; aged 35-76 years) with the soft tissue defects in the lower limb underwent immediate reconstructive operations with DIEP flap after their tumor resection. The defects ranged in area from 11 cm×7 cm to 25 cm×10 cm after extended resection, including 5 cases of bone exposure. The DIEP flap area ranged from 11 cm×8 cm to 26 cm×18 cm. Among them, 9 cases were treated with free transplantation and 2 cases with pedicle transplantation. The donor sites were closed directly. The patients' limb function, tumor recurrence and the healing of surgical incision had been followed-up.

Results
Eleven flaps survived and the donor sites healed directly. One flap had skin pigmentation due to postoperative vascular crisis, and the other flaps had satisfied texture and appearance. All patients were followed-up from 6 to 30 months. The lower limb movement was normal. All the donor sites had a good healing with no pain and abdominal complications. No tumor recurrence was observed during the followed-up period.

Conclusion
DIEP flap have many advantages, such as large cutting area, which is suitable for large-area wound repair after extended excision of soft tissue malignant tumor in lower limb. At the same time, the perforator vessel is constant and the caliber are thick, also the donor area is concealed and can be sutured directly. This kind of the technique for reconstruction of lower limb soft tissue defects after malignant tumor resection is well acceptable.

Key words:
Deep inferior epigastric perforator flap; Lower limb; Soft tissue malignant tumor; Wounds after excision; Repair


Applications that rely on the user authentication information is performed in the application container of the computing device. Application container, including a plug receiver module and the proxy module. When a request for authentication is started, the user is prompted to connect the remote identification device to the computing device. Remote identification device stores an encrypted version of the user private code. Plug receiver module reads the encrypted version of the user private code, communicates encrypted information to the remote authentication server. Remote authentication server decrypts the user private code, to identify and communicate the corresponding user authentication information to the agent module, using the decrypted user private code. Proxy module, by making available an application that is running the user authentication information in the application container to establish an authenticated session.


Meeting tirae : 7 : 00 A.M. Load busses on Telegraph Avenue at Sather Gate. Turn left around block and right (west) on Bancroft Way. Turn r ight (north) on Ful ton and Oxford to Universi ty Avenue. 0 .4 Turn left (west) on UNIVERSITY AVE. Proceed west through Berkeley to U.S. Highway 40. (Fig. 1.) 2.5 Turn r ight (north) on Highway 40 (Eastshore Freeway) tQward Vallejo. 3.8 The isolated, tree-covered hill ahead is E1 Cerrito (" Little Hill "), or Albany Hill. Now covered with eucalyptus trees on this side, in old pictures it was seen to be strikingly bare. These trees were introduced from Australia and were planted widely in western California. The hill is made of weathered sandstones of the Jurassic Franciscan formation, a complex of sandstone, shale, radiolarian chert, ultrabasie igneous rocks (in part serpentinized), and associated metamorphic rocks. This knob remains as an erosional r emnan t surrounded by the softer alluvium. The sandstone m a y be observed in old quarry workings on the west side of the hill (Jenkins, 1951, p. 339). 4.7 RICHmOnD CItY LIMITS, CONTR~ COS~A COTJ~Ty LINE. Northward, Highway 40 traverses low bay-margin land through Richmond and San ]?able. I n proSpanish days this area was thickly populated by Indians. Many shell mounds mark their ancient camp grounds and have yielded numerous artifacts. The region was first settled by the Spanish in 1826, and became par t of a Spanish grant, Rancho San ]?able. Remains of two adobes from the early Spanish period still stand.


Objective:To develop an analysis method of simultaneously determining [luteolin-7-Ogentibioside(LGT),luteolin-7-O-β-D-glucopyranoside(LGCOP),luteolin-7-O-β-D-glucuronopyranoside(LGCRP),apigenin-7-O-β-D-glucopyranoside(AGCOP),apigenin-7-O-β-D-glucuronopyranoside(AGCRP),luteolin(LI) and apigenin(AGI) ] in Kudiezi injection by RP-HPLC-DAD.Method:0.05% formic acidacetonitrile and 0.05% formic acid-water as the mobile phase,chromatographic column was Waters Symmetry C18(3.9 mm ×150 mm,4.6 μm) in gradient elution mode with velocity:1 mL·min- 1,column temperature 35 ℃,detection wavelength of 340 nm.Result:There were perfect chromatogram with good separation.All the 7 calibration curves showed a good linear relationship.The recoveries were 99.0%-101.5%,according to the requirement.The developed method was successfully applied for the simultaneous determination of the 7 components(LGT,LGCOP,LGCRP,AGCOP,AGCRP,LI,AGI).After the determination of 8 batch of Kudiezi injection,the content of 7 flavonoids was in 0.157 9-103.4 mg ·L- 1.Conclusion:The method is convenient,specific,and can be used for the flavonoids constitutes quality control of Kudiezi injection.


We are given "merely the data of our consciousness [...] we are free to choose which elements we wish to apply in the construction of physical reality."[1] With this ingenious reflection Albert Einstein educes that theories are what we make of them, similar to 'lenses' we 'wear' them in order to observe, comprehend and construct the material world. With respect to International Relations (IR), the political scientists "who are in love with practice [but] without knowledge are like the sailor who gets into a ship without rudder or compass and who never can be certain whether he is going."[2] Therefore, given that theories are arbitrarily applied in this very same way – as preferred guidance through the complexity of reality – they are inherently dependent upon subjective interpretations of the world simply because theories are "the product of human ingenuity and creativity."[3] Indeed, when we interrogate ourselves on central questions for explaining IR we tend to be driven by theoretical preferences, and in doing so we are going to have a specific perspective. As a consequence, in order to facilitate the arduous challenge of comprehending world politics, and in this particular case for unravelling the sources that drive military change, theories are conceived.


In recent years, fast multiple based methods, fast low-rank compression methods, and FFT-based methods have been developed that dramatically reduce the memory requirement of the iterative integral-equation (IE) solvers to O(N), and the CPU time to O(NlogN) for electrodynamic problems, with N being the number of unknowns. Compared to iterative solvers, direct solvers have advantages when the number of iterations is large or the number of right hand sides is large. In this work, an H2 matrix [1] was constructed to represent the dense system matrix resulting from integral-equation-based analysis of electrodynamic problems. The H- and H2-matrix framework is a general mathematical framework that enables a highly compact representation and efficient numerical computation of dense matrices. It was shown that the storage requirements and matrix-vector products of H2 matrices are of complexity O(N) [1-3]. However, the complexity of H2-matrix-based inverse has not been clearly established in the literature. In this work, based on the H2-matrix representation, a direct inverse of O(N) operation count and O(N) memory complexity was developed to solve the dense system matrix arising from electromagnetics-based analysis. Both complexity and accuracy were demonstrated. The method is kernel independent, and hence is suitable for any integral-equation-based formulation. In addition, it is applicable to arbitrary structures.


The invention relates to a device for sealing a bottle with safety to prevent the flow of the closure device liquide.Ledit comprises: .A rotary shutter consisting of an inner shell (6) and an outer shroud ( 7) each respectively having an opening (8) and (10) off-center, the inner shroud (6) being embedded in the outer ring (7). An internal thread (9) of the inner shroud (6) allows to fix the rotary shutter to the threaded neck (12) of the bottle (13) .. A nipple (3) inserted in a retaining ring (4) having a internal thread (11) is attached to the threaded neck (5) of the rotary shutter. A cap (2) is provided, which can protect the nipple (3) .The device according to the invention is particularly suitable for sealing the bottle.


Terrestrial cyborg insects are biohybrid systems integrating living insects as mobile platforms. The insects' locomotion is controlled by the electrical stimulation of their sensory, muscular, or neural systems, in which continuous pulse trains are usually chosen as the stimulation waveform. Although this waveform is easy to generate and can elicit graded responses from the insects, its locomotion control efficiency has not been consistent among existing literature. This study demonstrates an improvement in locomotion control by using a new stimulation protocol, named Burst Stimulation, to stimulate a cyborg beetle's antennae (Zophobas morio). Modulating the continuous pulse train into multiple bursts enhanced the beetle's turning responses. At the same stimulation intensity (amplitude, pulse width, and active duration), the Burst Stimulation improved the turning angle by up to 50% compared to the continuous waveform. Moreover, the beetle's graded response was preserved. Increasing the stimulation frequency from 10 Hz to 40 Hz raised the turning rate by 40 deg/s. In addition, the initial implementation of this protocol in the feedback control-based navigation achieved a success rate of 81%, suggesting its potential use to optimize further the autonomous navigation of terrestrial cyborg insects.


We have determined the Cu local density of states in CuAu I by utilizing the Cooper minimum phenomenon in the Au 5[ital d] photoemission cross section. To assist the analysis we carried out fully relativistic x-ray photocurrent calculations using the potential functions and densities of states from electronic structure calculations of CuAu I based on the relativistic Korringa-Kohn-Rostoker method. The good agreement between the experiment and theory suggests that the latter scheme provides a realistic description of the Cu local density of states in CuAu I.


—The herpetofauna of Zambia has been relatively well-studied, although most surveys were conducted decades ago. In western Zambia in particular, surveys were largely restricted to a few centers, particularly those along the Zambezi River. We here report on the herpetofauna of the Ngonye Falls and surrounding regions in south-western Zambia. We recorded 18 amphibian, one crocodile, two chelonian, 22 lizard, and 19 snake species, although a number of additional species are expected to occur in the region based on their known distribution and habitat preferences. We also provide three new reptile country records for Zambia (Long-tailed Worm Lizard, Dalophia longicauda, Anchieta's Worm Lizard, Monopeltis anchietae, and Zambezi Rough-scaled Lizard, Ichnotropis grandiceps), and report on the second specimen of Schmitz's Legless Skink, Acontias schmitzi, a species described in 2012 and until now known only from the holotype. This record also represents a 140 km southward range extension for the species.


Abstract A case of accidental severe carbon tetrachloride poisoning is described in which recovery appears to have been made possible by means of exchange blood transfusions at a critical stage of uremia. After complete recovery the patient died about four months later from a fulminant homologous serum hepatitis. Limited postmortem examination showed hemorrhagic necrosis of the pancreas and massive necrosis of the liver. A brief review is presented of the use of exchange transfusions and extrarenal excretion methods (peritoneal and intestinal lavage and the artificial kidney) in the management of lower nephron nephrosis. Homologous serum hepatitis may represent a serious complication of exchange blood transfusions. Data are presented which indicate that carbon tetrachloride poisoning in industry and among incidental and household users continues to be a significant clinical and public health problem. In five states two hundred seventeen cases of carbon tetrachloride poisoning were recorded for the three-year period 1949 to 1951 with a 10 per cent mortality. The authors are of the opinion that the public should be more fully informed of the potential serious toxic effects of carbon tetrachloride. Small as well as large quantities of this solvent should be labeled with the prominent display of the word POISONOUS in addition to the usual skull and crossbones insignia.


Pole-to-pole oscillation of the Min system mediates the cell division site placement that underlies the spatial and temporal organization of the Min proteins. This study reports dynamic modulation of the concentration gradient as the cell elongates, which is coupled with a near constant oscillation period under a given growth condition. The changing concentration gradient leads to gradual clearance of MinD at midcell, causing progressive relief from the inhibitory effect of the Min system on the assembly of the FtsZ ring. This concentration gradient differs among cells growing with different carbon sources or concentrations, which is in synchrony with the daughter cell sizes after division. The carbon stress responses of the MinD concentration gradient involve regulation by the sigma factor RpoS. Taken together, the results showed the plasticity of Min oscillation over the cell cycle that gradually sets up the assembly of the FtsZ ring.


A highly pathogenic form of avian influenza of the H5N1 subtype emerged in Hong Kong in 1997, rapidly infecting wild and domesticated birds and spread among these populations to several countries in Asia, Africa, and Europe. This virus also proved capable of infecting humans. It was hypothesized that should human-to-human transmission of such a virus become efficient, domestic wastewater and drinking water treatment systems could become contaminated with the virus, potentially exacerbating the spread of this disease. The objectives of this work were to determine if a surrogate virus, H5N2 avian influenza virus (a virus with no history of infecting humans, hereafter referred to as "H5N2") is inactivated by UV radiation, chlorination, and anaerobic digestion. Infectious H5N2 was not detected in phosphate buffer and wastewater effluent at fluences greater than 10 mJ/cm2 and at Ct values, based on free residual chlorine, greater than . In bench-scale anaerobic digesters, H5N2 dropped from an initial concentra...


Experimental details concerning asymmetric 1,4-reduction of β -silylated -β,β -disubstituted enoates catalyzed by CuH are described. High yields and enantiomeric excesses are to be expected when Solvias' JOSIPHOS bis-phosphine PPF-P( T-Bu) 2 is used as a nonracemic ligand.


We present a conjecture that the universal enveloping algebra of differential operators ∂/∂tk over C coincides in the origin with the universal enveloping algebra of the (Borel subalgebra of) Virasoro generators from the Kontsevich model. Thus, we can decompose any (pseudo)differential operator to a combination of the Virasoro operators. Using this decomposition we present the right-hand side of the Givental formula [math.AG/0008067] as a constant part of the differential operator we introduce. In the case of CP1 studied in the paper by Song and Song [hep-th/0103254], the left-hand side of the Givental formula is a unit, which imposes certain constraints on this differential operator. We explicitly check that these constraints are correct up to O(q4). We also propose a conjecture of factorization modulo Hirota equation of the differential operator introduced and check this conjecture with the same accuracy.


Twenty‐four psoriatic patients on methotrexate were studied with liver biopsies and serum measurements of aminoterminal propeptide of type III procollagen (PHI NP). All but one of nine patients with scrum levels of PHI NP above the normal range had liver fibrosis or cirrhosis and no normal liver biopsies were obtained in this group. In contrast, nine normal liver biopsies and two biopsies with minimal fibrosis were found among the 15 patients with normal serum levels of PHI NP. The study indicates that aminoterminal propeptide of type III procollagen can be utilized as a valuable non‐invasive marker of fibrogenesis in the liver. This analysis is not specific for the liver, but it seems that the number of liver biopsies probably can be reduced in psoriatics on methotrexate who have normal levels of PHI NP.


PT. XYZ is a company that moves in glue manufacturing. The business activities includes purchases of raw materials, manufacturing process, and finished goods sales. The company implemented OpenERP which focused on Purchase and sales modules to integrate their business processes. OpenERP implementation uses Accelerated SAP (ASAP) methodology. Initial stages in the ASAP method are preparing schedules, purposes, and scope. Followed by, collecting data through interviews and observations. Then analyze business processes and problems, as well as the user requirements using difference table analysis. From the analysis, the consultant identified the problems that exist. After getting the requirement, conducted stages of planning new business processes or Blueprint. The Blueprint contains the system running now (as-is) and the design of the system that will be applied (to-be) which will be used in the realization stage to perform configuration, customization, data migration and testing interfaces. The next stage is the final preparation, where consultants will conduct final testing, create a user manual and conduct user training. Once this step is done, the implementation of the system will go live towards the stage and the system has been confirmed free of bugs and user needs are met.


This paper offers some considerations on using Internet –hypertext, chats, and e-mails– as a means to teach philosophy. This study is supported, on one hand, on Heidegger's philosophical ideas on technology and its relationship with human beings; on the other, on applied theories of technology. The study shows that Internet has a positive impact on the teaching of philosophy since it facilitates man's comprehension of the word, of himself, and his role as a world citizen; therefore, it contributes to man's existential realization. It is concluded that Internet does fulfil its role as mediator among men and the essence of their technical task, becoming a bridge for the renewal of man and being.


Objective To establish gas chromatographic method for determination of methanol in biological samples.Methods The biological samples including blood,urine and content of stomach were placed in head-space vial,and added sodium chloride and water for gas-liquid equilibrium under 60℃ water-bath for 20 minutes,external standard quantification was used for definite quantitative determination.Results For spiked level of 0.10-1.00mg,the recovery rate of the method was in the range of 94.7%-102%,with the relative standard deviations of 3.5%-6.3%.Conclusion This method is simple,reliable,accurate and suitable for the determination of methanol in biological samples.


N‐substituted BZT analogs with high dopamine transporter (DAT) affinity and slow onsets of effect decreased cocaine self administration (SA) in rats (JPET 329:677). The present study examined additional N‐substituted 4′,4″‐diF‐BZT selective DAT inhibitors, with DAT affinities of 5.59 to 29.2 nM, and relatively faster onsets of action [JHW 013 (N‐methyl‐cyclopropyl‐diF‐BZT), GA 1–69 (N‐ethyl‐3‐indole‐diF‐BZT), GA 2–50 (N‐(R)‐2″‐amino‐3″‐methyl‐n‐butyl‐diF‐BZT) and GA 2–99 (N‐2″‐aminoethyl‐diF‐BZT)]. Rats were trained with cocaine SA (0.032–1.0 mg/kg/injection, IV) under fixed‐ratio 5‐response schedules of reinforcement. Maximal response rates were maintained by 0.32 mg/kg/inj of cocaine or by a standard DAT inhibitor, nomifensine (0.1 mg/kg/inj) when substituted for cocaine. Lower response rates were maintained at higher and lower doses. Responding was virtually eliminated when responses did not produce injections, and none of the BZT analogs maintained responding above those levels. Pretreatment (IP) with nomifensine dose‐dependently shifted the cocaine SA dose‐effect curve leftward. In contrast, the BZT analogs (IP) dose‐dependently decreased cocaine SA at lower doses than those that decreased response rates maintained by food reinforcement. The present study further supports the development of N‐substituted BZT analogs as medications to treat cocaine abuse. Supported by NIDA IRP.


The phase composition, acidity, basicity, degree of dispersion, and distribution of the active components throughout the volume of a grain of a nickel-vanadium-antimony catalyst supported on ..gamma..-Al/sub 2/O/sub 3/ have been studied. It has been shown that the shaping of the surface depends greatly on the nature of the modifying electrolyte. It has been postulated that the diffusional stoichiometry appearing during multicomponent impregnation determines the distribution, the degree of dispersion of the phase, and, consequently, the catalytic activity and selectivity of the catalyst in the oxidative dehydrogenation of n-butane.


Branched polymers, the formation of which is controlled by a finite monomer supply or by termination, are studied with a Monte Carlo simulation. The radius-mass dependence of the two models (in dimension from 2 to 8) is unequal, showing that branched polymers in toto cannot be identified with "animals." Study of the growth of mass with time helps to interpret the result.


This paper applies the concept of real-time process scheduling to a Dynamic Voltage Scaling (DVS) microprocessor. DVS allows a microprocessor to save energy by operating at the optimal voltage for the task at hand. Efficient operation requires a new class of algorithms which we term voltage schedulers. The necessary foundation for these algorithms is presented along with the foreseen implementation difficulties.


Driver distraction is an important cause of crashes and has emerged as a major issue in road safety nowadays in the whole world. Drivers are distracted due to multiple reasons while driving. Distraction is allowed if it is at an acceptable level which can be adapted by the drivers for safe driving. But under certain conditions these adapted strategies fail and cause crashes on the road. Though distraction had been given a vital importance throughout the world in recent years, no such research studies were carried out in Bangladesh. Indeed, Bangladesh is facing considerable road safety challenges. As many as 50 people are killed in road traffic crashes daily. Vulnerable road users are the worst sufferers being by far the largest group of the mishap. Distraction and inattention of drivers of heavy vehicle such as trucks and buses including minibuses play a significant role in the causation of such crashes and casualties. Therefore, the necessity was felt to carry out a research study on the extent, nature and causes of distraction of drivers in Bangladesh for taking pragmatic actions that may help reduce distraction crash risks. The study in particular focuses on the prevalence and effects of distracting activities of drivers while driving in Bangladesh. This paper summarizes some preliminary insights into these factors, activities and issues of drivers' distraction in Bangladesh. The drivers' behavioral problem characteristics dictate that there is a real need for strengthening effort in bringing about changes in attitudes of drivers towards safe driving through minimizing the driver distraction activities.


Acute coronary syndromes (ACS) are prevalent, portend a poor prognosis and represent the most threatening manifestation of coronary artery disease. While very little doubt exists about the clinical benefit of restoring culprit vessels' patency in patients admitted for ACS, the risk stratification and individual treatment strategy in these complex scenarios is not always straight forward. This is because the extension of myocardial damage and left ventricle recovery are difficult to predict, and a sizable proportion of patients admitted for ACS have bystander multivessel disease. This review summarizes available literature on the adjuvant role of invasive coronary physiology indices in guiding treatment and providing further risk stratification in patients suffering from ACS.


An endoscope-assisted myringoplasty technique with small endoscopes concentrates on the tympanic membrane itself without interfering with the surrounding healthy tissues and structures of the middle ear. Emphasis is placed on the tympanoscopic visualization of the tympanal side of the tympanic membrane to eliminate the possibility of epithelial ingrowth. Some myringoplasty techniques ignore the visualization and securing of the medial surface of the tympanic membrane.


The Czech Green Party was founded in 1990, but gradually marginalized and forgotten by both the voters and the media. A critical moment appeared when leading activists of environmental movements and former dissidents joined the party after 2002. In the 2006 election the Greens succeeded in getting 6.29 percent of the vote and six seats in the parliament. Clearly, this article aims to examine the party organization, its program and the internal relations of the Czech Greens.The Czech Greens share common features of the New Politics party: electorate profiles and framework party. One feature, however, participatory party organization, is not fully applied to the party. With respect to the program, the Czech Greens have a distinct characteristic. While programmatic orientation of the New Politics is related to some left-wing policies, the program of the Czech Greens shows liberal orientation.Since the party congress 2003 the presidium was dominated by leading activists of environmental movements. Because of their adamant way, sources of discontent accumulated between the party memberships, particularly former dissidents. In the congress 2005 the presidium was replaced by new chairman Martin Bursik and left the party. Under the new administration, the Czech Greens turned toward liberal tendency and aimed at entering government with Civic Democratic Party. Opposing to this course, former dissident Petr Uhl asserted that the Greens should be opposi-tion. Uhl played a fundamentalistic role in contrast with realistic position represented by Bursik.It is impossible to forecast whether the Czech Greens would be maintained in the Czech party system. The Greens, however, could have the advantage of a member of the European Greens.


Effect of cherry tomato grafting was studied by using cherry tomato as scion,"Nongyou" wild eggplant and Zhenmu No.1 as root stock.The results indicated that the control efficiency on P.solanacerum increased,the yield was increased by 44.9%~56.3%,and the fruit's Vc content was increased by 13.1%~18.3%.


AbstractThis study reports the different effects of tropical and subtropical sea surface temperature anomalies (SSTAs) on the mean tropical cyclone (TC) genesis location in the western North Pacifi...


Event cameras offer many advantages for dynamic robotics due to their low latency response to motion, high dynamic range, and inherent compression of the visual signal. Many algorithms easily achieve real-time performance when testing on off-line datasets, however with an increase in camera resolution and applications on fast-moving robots, latency-free operation is not guaranteed. The event-rate is not constant, but is proportional to the amount of movement in the scene, or the velocity of the camera itself. Recently, algorithms have instead reported a maximum event-rate that can be achieved in real-time. In this paper we present the event-driven framework used on the iCub robot, which closes the loop between algorithm processing rate and the actual event-rate of the camera in order to smoothly control and limit the latency, while allowing the algorithm to degrade gracefully when large bursts of events occur. We show two algorithms that process events differently from each other and demonstrate the trade-off between latency and algorithm performance that the framework provides.


The thesis changes the traditional defination that the stories about sprites in the medieval times is fiction.It revises its value from the viewpoint of folktale category theory and finds that those stories recorded in principle of seeking for reality are usually to be the Chinese edition of those which are spreaded world wide.Those texts are recorded very early and they surpass all the non Chinese editions as the western collectors can see.So,they are of high historic value.


Realizing the potential for growth and capitalizing on opportunities for Northern Australia requires effective supply chain networks. Agriculture is an important sector in the Northern Australian economy with significant production capabilities and the potential for creating national economic benefits. Northern Australia's fundamental supply chain deficiency constitutes the key source of comparative disadvantage the region faces, despite its significant resources, people and locational advantages. Drawing on reviews of several previous studies, critical analysis of the current value chain situations and consultations with key stakeholders, this article argues that there is a need to re-thinking agricultural supply chains in Northern Australia. Several issues impeding the connectivity between production and market require systematic consideration, including the priorities for Northern agricultural development, integrated supply chain planning, workforce shortages and skills gaps, supply chain infrastructure, capitalizing on Asian market opportunities, transport and non-freight subsidies, east-west and north-south supply chain hubs and improved coordination and collaboration. Corona Virus Disease-2019 has had serious impacts across the supply chains; therefore, re-thinking supply chains is crucial as the business as usual approach is not sustainable. It is now a critical time to re-think supply chains to address the challenges of developing effective and resilient Northern supply chains to enhance agricultural expansion and boost the national economy.


Inspired by precision tests of the Standard Model in future lepton colliders, the numerical analysis of the following scattering processes, $e^+e^- \rightarrow Z h^0\gamma$ and $e^+e^- \rightarrow Z H^0 \gamma$, are carried at the tree level including all possible diagrams in the two-Higgs-doublet model (2HDM). This model has many free parameters, but the parameters which take part in the scattering amplitudes of these two processes are primarily the mixing angle parameter, $s_{\beta-\alpha}$, and the masses of the neutral Higgs bosons, ($h^0, H^0$). Therefore, measuring the production rates of $Z h^0\gamma$ and $Z H^0 \gamma$ final states open another test for the scalar sectors of the 2HDM. The numerical analysis is performed under the current experimental constraints. The production rates and the asymmetry in the forward-backward direction are presented as a function of the center-of-mass energy covering the future lepton colliders. The unpolarized cross-section gets up to 6.19 (4.86) fb at $\sqrt{s} = 350$ (500) GeV and 0.164 (0.157) fb at $\sqrt{s} = 350$ (500) GeV for $e^+e^- \rightarrow Z h^0\gamma$ and $e^+e^- \rightarrow Z H^0 \gamma$, respectively. The polarization of the incoming $e^+e^-$ beams are studied for various configurations, and it enhances the cross-section by a factor of 1.78 in both processes for $P_{e^+,e^-}=(+0.6,-0.8)$.


Diffusion tensor imaging is widely used in research and clinical applications, but still suffers from substantial artifacts. Here, we focus on vibrations induced by strong diffusion gradients in diffusion tensor imaging, causing an echo shift in k‐space and consequential signal‐loss. We refined the model of vibration‐induced echo shifts, showing that asymmetric k‐space coverage in widely used Partial Fourier acquisitions results in locally differing signal loss in images acquired with reversed phase encoding direction (blip‐up/blip‐down). We implemented a correction of vibration artifacts in diffusion tensor imaging using phase‐encoding reversal (COVIPER) by combining blip‐up and blip‐down images, each weighted by a function of its local tensor‐fit error. COVIPER was validated against low vibration reference data, resulting in an error reduction of about 72% in fractional anisotropy maps. COVIPER can be combined with other corrections based on phase encoding reversal, providing a comprehensive correction for eddy currents, susceptibility‐related distortions and vibration artifact reduction. Magn Reson Med, 2012. © 2011 Wiley Periodicals, Inc.


Abstract Labov defined the linguistic variable as "a class of variants which are ordered along a continuous dimension and whose position is determined by an independent linguistic or extralinguistic variable" (1966:15). A precondition for identifying surface forms as variants of a single variable is semantic, or truth-conditional, equivalence. This requirement proves hard to apply beyond (morpho)phonology, and was subsequently relaxed into one of functional equivalence. The focus of this article is pragmatic variation and how we should interpret functional equivalence to account for this. It is proposed that the variants of a pragmatic variable share a common procedural meaning, defined as a set of instructions guiding the inferential phase of utterance interpretation. Recasting the core meaning of pragmatic variables in procedural terms allows us to co-examine alternating forms that may express different referential meanings, remaining true to the spirit of Labov's proposal, who saw linguistic variables as socially motivated clusterings of forms. (Pragmatic variation, functional equivalence, procedural meaning, Relevance Theory)*


Herein we present a case of Neisseria meningitidis-related sepsis and meningitis in a 60-year-old woman. The N. meningitidis strain was identified as serogroup B and sequence type (ST)-4893 by multilocus sequence typing (MLST). The patient in this case had visited France prior to development of symptoms. No meningococcal isolate belonging to ST-4893 has been identified in Japan previously, whereas an ST-4893 strain from France has been reported in the MLST database. These results strongly suggest that this case is likely to have been imported from France.


Tony Albert's work reveals that it is the things we can't see or touch that can often carry the most weight. The Queensland-born conceptual artist uses the hidden tonnage of the words and images that form our identity as his medium, giving us an opportunity to reflect on both our personal and collective past. In recent weeks Sydney-based Albert has been filming episodes for NITV's Colour Theory series, preparing for an upcoming residency at ISCP (International Studio and Curatorial Program) in Brooklyn, New York, participating in a print workshop and, in between, developing new work (and a publication) for a solo exhibition at Sullivan + Strumpf in Sydney. At the same time, Albert's ambitious new memorial in the city's Hyde Park - a public artwork to honour Aboriginal and Torres Straight Islander men and women who have served their country - is being unveiled. This is testament to the critical acclaim and recognition he has earned as an artist, with work that has the potential to not only bring forth the voices of Indigenous Australians, but to rewrite and reaffirm our history as a nation. On the eve of the official opening of Yininmadyemi - Thou didst let fall (2015) in Hyde Park, the artist spoke about the public and private strands of his practice, the power of untold stories to transform history, and the duality of meaning within his work.


Mozzarella is one of the most popular unripened Apulian cheeses. Knowledge about microbial composition and variability of artisanal mozzarella and its production chain is increasingly growing. In this study, microbial communities from natural whey starters to end products from four renowned Apulian artisanal dairy factories have been explored by means of 16S metagenomics. The chemical properties of mozzarella samples were also detected and analyzed. Lactobacillus is the core acidifying component of the used starters, while some psychrophilic or contaminants bacteria appear in site-specific products. Biodiversity was found to be quite similar between the whey and mozzarella sample pools, while a significant variability among production sites (factories) has been detected. Furthermore, mozzarella microbial diversity seems to be in positive correlation with its lactic acid content. Targeted metagenomics would then be a powerful and relatively quick technique to characterize the microbiological variability of traditional milk-based foods.


See related article, pp 327–332

Atrial and brain natriuretic peptides (ANP and BNP) possess important regulatory cardiorenal functions, such as promoting natriuresis, diuresis, vasodilatation, and activation of antihypertrophic responses on pathophysiological stress. Release of ANP and BNP is significantly increased in response to atrial and ventricular stretch, respectively. Both ANP and BNP are produced and stored as prohormones and are present in the circulation as a mixture of propeptide and active 28- and 32-amino acid, carboxyl-terminal peptide hormones, respectively.1

Both ANP and BNP bind to the natriuretic peptide receptor-A, which is coupled to particulate guanylate cyclase to generate cGMP, the primary second messenger mediating downstream signaling cascades in target tissues. Despite stimulation of the same receptor, the physiological effects of ANP and BNP are somewhat different: ANP predominantly regulates sodium-water homeostasis and blood pressure, whereas BNP has more antihypertrophic effects, although there is substantial overlap.1

In theory, increases in generation of ANP and BNP in response to myocardial stretch should occur as part of compensatory mechanism(s) to restore homeostatic balance. However, the lusitropic, antihypertrophic, and natriuretic effects of ANP and BNP are significantly attenuated in congestive heart failure despite a considerable apparent increase in plasma concentrations. It is now increasingly accepted that the key reason for this discrepancy is because of variable activation/processing of natriuretic peptides, resulting in much greater proportion …


A CAREFUL formulation of the probability and economic model which , underlies observations is indispensable for the choice of correct statistical procedures to be followed in drawing econometric inferences from samples. The sample design, the methods of collecting data, and underlying economic behavior will all contribute to the formulation of the model. The study of data collected in consumer surveys' has convinced us that one cannot proceed simply by the application of conventional statistical methods in the estimation of economic relationships because of the existence of some basic difficulties which we classify as follows: (1) weighting of observations, (2) heteroscedasticity, (3) nonlinearities, (4) the choice of alternative economic concepts, (5) errors of observation. In this paper, we shall describe some empirical calculations that deal with the first four difficulties. The fifth is reserved for future study. Observations may be weighted because of the use of differential sampling rates and because of differential response rates to survey questions in the different strata of the population. High rent (a correlate of high income) areas are deliberately over-sampled because they show more variability in respect to certain economic variables than other strata, and conversely low rent areas are under-sampled. The strata also have different response rates. The weights finally used are combinations of sampling and response rates which attempt to give each stratum the same relative importance in the sample that it has in the population; i.e., they are essentially inversely proportional to the net (effective) sampling rate. The heteroscedasticity which leads to the adoption of differential sampling rates must also be taken into account in the estimation of parameters in equations expressing economic behavior. In these equations, the variance of the so-called disturbances is a fundamental parameter to be estimated, and this variance is not uniform over some


This research project contributed to the in-depth understanding of the influence of hydrologic and hydraulic factors on the stormwater treatment performance of constructed wetlands and bioretention basins in the "real world". The project was based on the comprehensive monitoring of a Water Sensitive Urban Design treatment train in the field and underpinned by complex multivariate statistical analysis. The project outcomes revealed that the reduction in pollutant concentrations were consistent in the constructed wetland, but was highly variable in the bioretention basin to a range of influential factors. However, due to the significant amount retention within the filter media, all pollutant loadings were reduced in the bioretention basin.


A sub-millimeter resolution ladar is demonstrated with 9.3km delay using stretched pulses allowing amplification to high powers with negligible nonlinear effects. A coherent heterodyne detection scheme results in 30dB dynamic range.


As a top tourist destination of China, and a problem area in real estate development, Hainan gains the superiorities of developing tourism real estate. This research firstly studied the characteristics of tourism real estate, and then analyzed the all kinds of conditions of developing tourism real estate in Hainan. The research found that developing tourism real estate could be an important way to change the model of tourism development of Hainan, and could be the main means to re flourish the real estate industry of Hainan too. So the conclusion is : developing estate tourism is not only feasible but also necessary to Hainan.


Common bean regional variety trial was carried out at Sirinka, Jari, Cheffa and West belesa (Gondar) from 2017 to 2019 cropping season. The objectives of the trial were to evaluate the performance of genotypes for grain yield and yield related traits and to select and promote the promising ones for verification. Fourteen genotypes including Awash-2 (standard check) were tested using RCBD. Analysis of variance and GGE biplot analysis was employed on multi-environment grain yield data. The combined analysis of variance showed significant differences for both main and interaction effects of genotypes, locations which led to exploit the significant effect of genotype-by-environment interaction. Based on the analysis of variance and GGE biplot analysis, two varieties namely DAB-413 and ZABR 16575-51 F-22 with average grain yield of 2729 kg/ha and 2501 kg/ha, respectively were selected, verified and DAB-413 and have been released for Sirinka, Jari, Cheffa and similar areas in Ethiopia. Therefore, DAB-413 has been recommended for the tested and other similar common bean growing areas to increase production and productivity of this crop.


The design of the South classical garden is affected by the confucianism and the taoism deeply.Based on the Confucian world view and philosophy of life,"The Harmony between Man and Nature"has become an unshakable principle that the South classical gardens follow.Based on the Taoist thought of"Imitation of Nature",the South classical gardens emphasize the key element of the natural landscape,pursue the aesthetic realm that " Done by man,as if since it is made".


In this paper, we present a novel sequence-to-sequence architecture with multi-head attention for automatic summarization of long text. Summaries generated by previous abstractive methods have the problems of duplicate and missing original information commonly. To address these problems, we propose a multi-head attention summarization (MHAS) model, which uses multi-head attention mechanism to learn relevant information in different representation subspaces. The MHAS model can consider the previously predicted words when generating new words to avoid generating a summary of redundant repetition words. And it can learn the internal structure of the article by adding self-attention layer to the traditional encoder and decoder and make the model better preserve the original information. We also integrate the multi-head attention distribution into pointer network creatively to improve the performance of the model. Experiments are conducted on CNN/Daily Mail dataset, which is a long text English corpora. Experimental results show that our proposed model outperforms the previous extractive and abstractive models.


Pathfinder Sea Surface Temperatures (SST) have been validated for the Mediterranean Sea using independent data obtained from MEDATLAS CTD and XBT casts. The Mean Bias is, in most of the case less than 0.5° C, with a mean value of 0.2 °C. The bias was uncorrelated to the number of Mediterranean matchups points used to evaluate the coefficients of the SST Pathfinder algorithm. This implies that Pathfinder data over the Mediterranean Sea represents a coherent time series of temperature that can be used for climatological applications. As an example of such an application the time series of the mean Mediterranean SST is discussed for the entire period of available data (1985–1996). The analysis shows evidence of interannual variability but does not suggest an evident increasing trend for SST as suggested by previous works. Comparison with corresponding meteorological data (COADS) confirms the close correlation between meteorological forcings and SST field.


The article highlights the apparent anomaly of the rise of cricket in the Arab-Gulf region. It argues that the evolution of cricket in the six Gulf Cooperative Council countries (GCC) from essentially an expatriate sport to its status today, with evident strengths and weaknesses, reflects the quality of the consolidation of the South Asian community, and especially of the Indian diaspora. The relationship between sports and the diaspora remains relatively unexplored. Using an empirical and comparative method, the paper adds to the current literature by studying the link between cricket and the diaspora in the Gulf region.


A 28-year-old female presented to the endocrine surgery clinic with complaints of the right breast lump for 3 months. Clinical examination revealed a 3 cm × 2 cm hard lump in the upper outer quadrant, suspicious of carcinoma breast with clinical staging of T2N0M0. Three years before this, she was diagnosed to have adenocarcinoma of the rectum and had undergone treatment. On serial follow-up, there was no evidence of locoregional recurrence of the disease. Ultrasound imaging of the right breast was suggestive of BI-RADS V lesion, highly suspicious of primary breast malignancy. However, the core biopsy was reported to be mucinous adenocarcinoma with immunohistochemical markers suggestive of a colorectal primary. Metastasis to the breast from a primary colorectal carcinoma is an exceedingly rare clinical entity. The imaging findings may not yield any characteristic differences between primary breast cancer and breast cancer due to metastasis from other cancerous primary. Biopsy of the lesion with relevant immunohistochemical markers remains the mainstay of the diagnosis. The overall prognosis is poor, and the treatment comprises oral capecitabine as a palliative agent with or without wide local excision of the metastatic breast lesion.


This work seeks to understand the definition of what mentoring is as well as the experience that has given when it has been used as a tool to develop the identity in the Benemérita Universidad Autónoma de Puebla. We must mention that importance that the mentoring process has taken place in BUAP and how it has generated a change and has imprinted an impact in the university community. At the same time such impact will be analyzed on the mentees and their perceptions on the usefulness of the activities that come from it. It is worth mentioning that specialists, as well as the activities carried out, have already analyzed the design of the mentoring at BUAP. Said analysis takes into account the needs and characteristics of the University's student community. This text shows, according to the results, how mentoring has a clearly developed social role in favor of the population


The problem on rights of "The Migrated Married Rural Women",which focuses on the distribution of compensation fee for land requisition,arises on the basis of the social transition in rural areas,the discovery of land value and the awakening of women's awareness of right protection.And the dispute on collective economic organizations membership has fully exposed the conflict between the development of productive forces and the stagnation of certain aspects of the superstructure in the course of rural social transition.The solving of this problem has become a sticky business for the government due to a variety of structural obstacles.Consequently,the only effective solution is to rely on the legislative,executive and judicial,supported by the reform of the rural collective ownership.


Following an application from GlaxoSmithKline, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim based on newly developed scientific evidence and including a request for the protection of proprietary data related to "toothkind" drinks and reduction of tooth demineralisation. The food constituent, "toothkind" juice drinks, which is the subject of the health claim, is sufficiently characterised. The Panel considers that reduction of tooth demineralisation is a beneficial physiological effect. The applicant identified 25 human intervention trials and 10 in vitro studies as being pertinent to the health claim. In weighing the evidence for reduced potential of "toothkind" juice drinks for demineralisation of dental enamel by reducing plaque pH, the Panel considers that "toothkind" juice drinks reduced tooth demineralisation when compared to sugar solution (10 g/100 ml) at an exposure frequency of seven times daily. No evidence has been presented for an effect at lower exposure frequencies. In weighing the evidence for reduced erosive potential, the Panel considers that "toothkind" juice drinks reduced tooth demineralisation when compared to typical conventional juice drinks at an exposure frequency of four times daily. No evidence has been presented for an effect at lower exposure frequencies. The Panel concludes that a cause and effect relationship has been established between the consumption of "toothkind" juice drinks and reduction of tooth demineralisation when compared to typical conventional juice drinks at an exposure frequency of four times daily and when compared to typical sugar-containing acidic non-alcoholic beverages at an exposure frequency of seven times daily.


The taxation of nuclear energy is studied using a stylized model of the electricity sector, with one dominant nuclear producer and a competitive fringe of fossil-fuel plants. We show that an unanticipated tax on nuclear production can generate significant government revenue in the short run without disturbing the market, but will harm investment incentives in the long run, especially if the government cannot credibly commit to a future tax rate. Even if the government is capable of credibly committing to an optimal long-run tax, government revenues from the long-run tax will be very low due to the market power of the incumbent. Lifetime extension agreements negotiated with multiple potential players, and competitive auctioning of new nuclear licenses are shown to be the most attractive policies. The analytical results are illustrated with a numerical simulation for the case of Belgium.


A biological specimen bank (BSB) is defined as a repository that may support single or multiple specimen types and one or more studies under controlled conditions that permit efficient retrieval and optimal stability of specimens. Physical characteristics of a bank can vary from a single freezer in the basement of a laboratory to a sophisticated facility complete with a state-of-the-art security system, computer database, and management structure. A well-


Extracts of buds and young shoots of a good cone-producing clone of Douglas-fir (Pseudotsugamenziesii (Mirb.) Franco) were tested for cone production effect on seed orchard Douglas-fir trees chosen for their history of poor cone production. Other metabolites, including gibberellin 4/7, arginine, and abscisic acid were also tested. Growth regulator levels in good and poor cone-producing clones of Douglas-fir were compared over the period of bud break and shoot elongation.No evidence was obtained for the presence of growth regulators critical to cone production in purified extracts from ramets of the good cone-producing clone. Applied gibberellin 4/7 increased male and female cone production. Crude extracts of a good cone-producing clone increased male cone bud production. Arginine and abscisic acid had no effect.Bioassays indicated that growth regulator levels in buds and young shoots changed greatly with stage of development but were similar in good and poor cone-producing clones.


The protection circuit (51), when the buffer capacitor (Cs1, Cs2) is charged to a predetermined voltage or more, the clamp diodes (Df1, Df2) is turned on, the buffer capacitor (Cs1, Cs2) of the end of charging.


Objective To evaluate the micro hardness of five kinds of composite resin teeth, including common composite resin teeth and Nano-composite resin teeth.Methods Micro hardness of five dinds of composite resin teeth were measured with Dynamic Ultra Mico hardness Tester.Results The new nano-composite resin teeth's Vickers hardness was 577.67Mpa, while the Vickers hardness of other four kinds of composite resin teeth were 427.67Mpa, 469.67Mpa, 706.33Mpa, 666.33Mpa respectively.Conclusion The micro hardness of the new material is better than common resin teeth, but not as hard as another two composite resin teeth of SHOFU.


Purpose – To develop CCT's practice perspective to increase the understanding of the consumption context and thereby of the sociohistoric patterning of consumption.

Design/methodology/approach – An ethnographic exploration of how the different practices involved in a consumption situation, like the everyday dinner among single mothers, contextualized consumption.

Findings – The chapter concludes that mothering, defined as a meta-practice, dominated the consumption situation and organized the other practices involved.

Originality/value – Introducing the concept of meta-practices having a major influence over our consumption and thus a type of practice consumption research should look for.


In the present paper we demonstrate that there exists a new type of neutron stars in the tensor-multi-scalar theories of gravity. We call this new type of neutron stars topological neutron stars. In addition to the standard characteristics of the usual neutron stars the topological neutron stars are also characterized by a topological charge. We numerical construct explicit examples of topological neutron stars in tensor-multi-scalar theories whose target space is $\mathbb{S}^3$. Besides the topological charge the topological neutron stars also exhibit other attractive features which can place them among the realistic compact objects that could exist in Nature. For example they possess zero scalar charge and thus evades the strong binary pulsar constraints on the dipole scalar radiation.


The reactions of 1,4(1,5)-diazido-9,10anthracenediones with phenylacetylene and methyl propiolate under copper(I)-catalyzed reaction of the azidealkyne cycloaddition conditions have been studied and a series of new 1,2,3-triazole derivatives of 9,10anthracendione have been obtained. The computer screening of synthesized compounds was carried out using the PASS Online software to identify areas of experimental biomedical researches. Compounds with high affinity to the receptors family of tyrosine kinases of the epidermal growth factor EGFR have been found among the newly synthesized 1,2,3-triazoles of 9,10anthracenedione using molecular docking. The results of molecular docking indicate a probable mechanism for the realization of antitumor activity.


The impact of genetic selection on the performance of layer hens has been dramatic. Hens reared in colonies now produce up to 350 eggs over an 80-week period. Free-range hens face additional challenges affecting gut health and shell quality. This requires nutritionists to provide a balance of key nutrients to sustain the health and welfare of the bird and to ensure the quality of the product.


To understand the influence of water treeing on the dielectric strength of polyethylene, an investigation of all the physically relevant parameters of the water tree (WT) controlling the inception of electrical breakdown is necessary. Usually only the water tree length is taken into account. The author proposes that the optical absorbance of the water tree, which is correlated with the water concentration, be measured. The principle of this method is explained, and it is shown that the optical absorbance of the water tree is related to the initiation of electrical trees in its vicinity in polyethylene samples.<<ETX>>


OBJECTIVE
Antibodies against carbamylated protein (anti-CarP) were found to be a promising marker to evaluate joint damage and disease activity in patients with rheumatoid arthritis (RA). However, whether anti-CarP antibodies were present in systemic lupus erythematosus (SLE) remained ambiguity. We have therefore undertaken this study to assess the levels of serum anti-CarP antibodies and to evaluate their clinical value in SLE.

METHODS
Serum levels of antibodies against carbamylatedfibrinogen (anti-CarP) were measured by enzyme-linked immunosorbent assay (ELISA) in 105 SLE patients and 73 healthy controls. Other clinical and laboratory measurements of the SLE patients were collected from medical records. Data analyses between anti-CarP antibodies and other laboratory measurements were performed using SPSS software for Windows 24.0.

RESULTS
The levels of serum anti-CarP antibodies in the patients with SLE were significantly higher than those in the healthy controls (P<0.05). There were significant differences between the anti-CarP-positive group and anti-CarP-negative group in many clinical features. The disease duration, values of ESR, CRP, RF, anti-cardiolipin, anti-dsDNA, D-dipolymer, IgA and IgG were significantly higher in the anti-CarP-positive group compared with the negative group (P<0.05). Conversely, the values of complement 3, complement 4, peripheral blood RBC, and hemoglobin were significantly lower in anti-CarP-positive group than in the negative group(P<0.05). Moreover, the incidence of increase of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factor (RF), D-dipolymer, decrease of peripheral blood RBC, hemoglobin, complement 3, complement 4, and positive rate of anti-dsDNA were significant different between the two groups(P<0.05). The positive rate of anti-CarP (21.9%) was higher than that of anti-Sm (15.24%), and close to anti-ribosomal P protein (22.86%) in our SLE patients. In addition, anti-CarP antibody was present in the SLE patients lacking the disease specific antibodies, including anti-Sm (anti-CarP positive rate 20.2%, 18/89), anti-dsDNA (anti-CarP positive rate 9.3%, 4/43), anti-nucleosome (anti-CarP positive rate 12.5%, 6/48), and anti-ribosomal P protein antibody (anti-CarP positive rate 20.9%, 17/81). Moreover, the high levels of anti-CarP antibodies were correlated with short disease duration, low C3, C4, RBC, and hemoglobin (P<0.05), high ESR, CRP, IgA, IgG, RF, anti-cardiolipin, anti-dsDNA, and D-dipolymer (P<0.05).

CONCLUSION
The level of anti-CarP antibody was increased in the serum of patients with SLE. There were correlations between anti-CarP antibodies and clinical and laboratory indicators of SLE patients.


An active cannula is a medical device composed of thin, pre-curved, telescoping tubes that may enable many new surgical procedures. Planning optimal motions for these devices is challenging due to their kinematics, which involve both beam mechanics and space curves. In this paper, we propose an optimization-based motion planning algorithm that computes actions to guide the device to a target point while avoiding obstacles in the environment. The planner uses a simplified active cannula kinematic model that neglects beam mechanics, and focuses on planning for the (piecewise circular) space curves. The method is intended for use in image-guided procedures where the target and obstacles can be segmented from preprocedure images. Given the target location, the start position and orientation, and a geometric representation of obstacles, the algorithm computes the insertion length and orientation angle for each tube of the active cannula such that the device follows a collision-free path to the target. We formulate the planning problem as a constrained nonlinear optimization problem and use a penalty method to convert this formulation into a sequence of more easily solvable unconstrained optimization problems. Simulations demonstrate optimal paths for a 3-tube active cannula with spherical obstacles. The algorithm typically computes plans in less than 1 minute on a standard PC.


The High Resolution Stereo Camera (HRSC) on Mars Express covers the surface of our neighboring planet in full color and 3D. Altogether, nine channels are obtained in stereo angles between ±18.9°. These data sets are well suited to derive Digital Terrain Models (DTM) and, based on that, color orthoimages. Both, photogrammetric standard processing of HRSC data as well as alternative and/or supplementary approaches are usually based on image matching or shape-from-shading. In contrast to classical matching between images – and aiming for the combined derivation of orthoimage, DTM, and reflectance properties of the Martian surface – HRSC data are processed using the Facets Stereo Vision approach, which is a flexible method for matching in object space. Transfer functions connect the object surface (surfels) with corresponding pixels in each image; the entire image content is treated as observables. The unknowns, in particular an orthoimage (brightness values) and a DTM (height values), are estimated in a combined least squares adjustment with respect to spatially regular grids in object space, i.e. the facets. Thus, existing interconnections between these models are implicitly regarded. In this context, an indirect approach of Facets Stereo Vision is utilized for the processing of HRSC data. It is implemented with MATLAB and applied for small Martian regions with varying surface characteristics. Exemplarily, the results for a steep crater rim and a comparatively flat region are presented and judged.


The advent of space-based coherent diode laser communication systems requires development of space-qualified laser diagnostics to make these systems robust in face of aging laser parameters. This paper describes the packaging and performance of a diagnostic system which sets the wavelength, tone spacing and optical power of a directly modulated frequency-shift-keyed GaAlAs laser transmitter.


-silenced plants identified by qRT-PCR were used for the physiological and molecular assays, and the hygromycin-resistant plants transformed with empty vector were used as control plants. The transcription factor MYC2, an important regulator of the jasmonic acid (JA) signaling pathway, plays a vital role in regulating plant growth and stress tolerance. In this study, the role of MYC2 in regulating the stomatal opening/closure and drought tolerance of rapeseed was studied using MYC2 -silenced transgenic plants, which were developed previously. Com-pared with that in the leaves of control plant, the stomatal closure in the lower epidermis of the MYC2 -si-lenced leaves was weaker under both light and dark conditions, which results in faster water loss and lower drought tolerance. The transcriptional assays showed that the expression of MYC2 is induced by JA and abscisic acid (ABA), and that silencing of MYC2 altered the expression of JA- and ABA-responsive downstream gens. These results are helpful to understand the regulation mechanism of jasmonate signaling pathway in drought tolerance of rapeseed.


This thesis explores the potential of utilizing metal-based plasma sources as a sustainable solution for high-powered electric propulsion and its implications for future interplanetary travel. Focusing on the Vacuum Arc Thruster and the Variable Specific Impulse Magnetoplasma Rocket engine, the study encompasses numerical simulations, analytical comparisons, and performance analyses to assess the feasibility of metal plasma fuels in space missions. The numerical analysis employs COMSOL Multiphysics to delve into the magnetohydrodynamics behavior within the VAT. Such simulation setup could provide valuable insights. Although the numerical results are disappointing for this paper, there exist possibilities within future work. The main hurdle is the simulation of vacuum. There are workarounds in COMSOL's Vacuum System Modeling tool which was not available for this thesis. Also, the used material properties were not suited for this high temperature plasma environment. The lack of material properties is a consequence of the insufficient research in the metal plasma field. Performance analysis is conducted on both the VAT and VASIMR engine, exploring efficiency, thrust capabilities, and feasibility for interplanetary missions. The results demonstrate the potential of metal-based plasma sources to reduce dependence on Earth for refueling and decrease mission costs. It is found that aluminum and magnesium have similar performance as the argon gas used in the VASIMR. Although challenges exist, such as integration problems and availability of material properties for metals in plasma states, the study underscores the promise of metal plasma fuels for sustainable space exploration. By advancing high-powered electric propulsion technologies, we move closer to realizing humanity's ambitious journey to distant celestial bodies. This research paves the way for future innovations, enabling a more self-sustaining space economy and unlocking new horizons of interplanetary travel.


This chapter presents an analysis, with appropriate quotations, of provisions of some multilateral conventions of worldwide scope whose purposes are to prevent or repress specific categories of offenses. Such conventions contain rules on extradition and deal with narcotics, genocide, unlawful acts against the safety of civil aviation, terrorism, physical protection of nuclear material and other subjects. In Article I of the Convention on the Prevention and Punishment of the Crime of Genocide, approved by the United Nations General Assembly on December 9, 1948 the Contracting Parties confirm that genocide, committed in time of peace or in time of war, is a crime under international law which they undertake to prevent and punish. According to Article III the following acts are punishable: (a) genocide; (b) conspiracy to commit genocide; (c) direct and public incitement to commit genocide; (d) attempt to commit genocide; (e) complicity in genocide.Keywords: extradition; genocide; multilateral conventions; narcotics; terrorism


In this paper, we present a method for detection and localization of vertical traffic infrastructure using video sequences recorded by a survey vehicle. Search for polelike structures in the images creates initial 2D hypotheses. They are fused on the groundplane to form 3D hypotheses which are finally verified and classified by search for the distinguished part of the infrastructure. Each step is followed by pruning the set of hypotheses using SVM classifier. The method was tested in a streetlight detection application with video sequences containing over one thousand streetlights.


Objective To explore the synergistic effect of VEGF and bFGF on microcirculation reconstruction and the flap viability of the ischemic flaps.Methods Fourty eight wistar rats were employed as animal model and were divided into four groups with 12 rats in each group.An ischemic skin flap measuring 7cm×1cm was established on the back of each rat with the pedicle at the tail side.The viable rate of the skin flaps and the dermovascular density of each flap were investigated by histological and histo morphometrical methods.Results The results indicated significant difference in the viable rate of flaps and dermovascular densities between VEGFbFGF group and the other three groups on the 7 th postoperation day.The structures and functions of fibroblast and vascular endothelial cell in the treated groups were better than that of in blank group.Conclusion We concluded that VEGF plus bFGF could accelerate the vascularization of the ischemic skin flap and enhance the viable rate of the flap synergisticaly.


ABSTRACT This paper attempts to describe how the Merah Bercerita music group builds the perception of Wiji Thukul's poem entitled "Flower and Wall" and pours it into a song. It is noteworthy that this musical work is not merely showing the phenomenon of mere musical performances, but also is an effort in giving musical power to the poetic text that is full of social criticism. In this qualitative research, data collection is done with emphasis on the concept of perception as the main perspective, then the data is interpreted to be analysed. The conclusion of this research is the existence of three stages in the process of perception conducted by Merah Bercerita group, namely (1) sensation, (2) attention, and (3) interpretation. Kata Kunci : persepsi, puisi, musik, bentuk musik


We have cloned and sequenced a cDNA of the human homologue of the Saccharomyces cerevisiae Suv3 putative RNA helicase which is indispensable for mitochondrial function in yeast. The human Suv-3-like protein has a typical mitochondrial leader sequence. Northern blot data and analysis of ESTs in the data banks indicate that this human gene (SUPV3L1) is expressed in practically all tissues, though at different levels. Sequence homology analysis has shown a strong conservation of the protein in a number of eukaryotic organisms -- plants, mammals and fungi, but no close homologues exist in bacteria with the exception of the purple bacterium Rhodobacter sphaeroides. This gene is thus ubiquitously present in all eukaryotic organisms.


Testing of individual production wells is significant for the design and operation of subsea satellite fields. Where long tiebacks are involved, the ability to monitor each well's output, with a multiphase meter near the wellhead, enhances the field's performance and value. Application of subsea multiphase metering to two U.K. North Sea satellite fields showed that this equipment operates successfully subsea. In-service experience has shown that deposits and debris can affect meter performance; however, provision for remotely operated vehicle (ROV) intervention enables these to be mitigated in a cost-effective manner.


An important priority of contemporary public policy is to strengthen U. S. industrial competitiveness through the transfer and commercialization of public-sector technology. However, the evolving collaboration between federal technology sources and private organizations presents critical strategic challenges. To avoid disappointment, it is imperative that all parties (federal agencies, contractors, and laboratories as well as potential private partners) understand the scope and complexity of these challenges, and that each partner know the constraints, resources, methods, and culture of the other.


Introduction: According to WHO, soil-transmitted helminth (STH) infections could infect up to 90% of children from deprived communities with unhygiene and improper sanitation lifestyle. In West Malaysia, commonly the aboriginal people (Orang Asli) is prone to be infected with STH infections. Albendazole (400mg) is an anthelminthic drug that has been used for more than 30 years to cure STH infections. Hence, the main objective of this project was to evaluate the efficacy of single-dose albendazole (400mg) against STH infections among Orang Asli. Methods: Stool samples were collected in Hulu Langat, Semenyih, Malaysia. Who had not previously undergone deworming treatment. The parasites were concentrated by floatation technique (using the standard salt-sugar solution) to extract the amount of helminths' egg before and after the albendazole treatment (400mg). Results: There were 44 participants after one-month post-treatment. The cure rate (CR) for Trichuris trichiura and Ascaris lumbricoides was
11.6% (n=5) and 35.0% (n=14), respectively. Moreover, there was no heavy infection for both STHs during the post-treatment of albendazole. Conclusion: The results indicated that the chosen anthelminthic showed higher cure rate efficacy in A.lumbricoides than T.trichiura. However, both species had decreased egg burden post-treatment with albendazole.


Ananas comosus (L.) Merr., which is commonly known as pineapple, is a well-studied plant for its medicinal properties. In terms of commercial importance, it ranks third among tropical fruits. It has been used for its antidiabetic, antimalarial, anticancer, abortifacient, antioxidant, and antidiarrhoeal activities. This review was planned to study the antiviral effects of pineapple and its bioactive compounds against SARS-CoV-2.

Research methods comprise significant studies on the treatment of COVID-19 utilizing pineapple and its bioactive compounds. To carry out the e-literature review, articles were downloaded from online search engines, including Elsevier, PubMed, and Google Scholar, using pineapple, bioactive compounds, bromelain, clinical trial, and COVID-19.

The literature showed that pineapple and its bioactive compounds showed antiviral effects in COVID-19 patients by inhibiting the proinflammatory cytokines and affecting various signaling molecules, including NF-kβ, proinflammatory cytokines, and cyclooxygenase-2. They modulate apoptotic protein levels and also cause a reduction of ACE-2 and TMPRSS2 expression.

For the development of phytomedicine that adheres to all safety regulations, pineapple, and its bioactive compounds can serve as lead molecules for clinical studies in SARS-CoV-2 infection treatment and therapy.


Aiming at the current status that generating Digital Surface Model(DSM)of high precision is in low efficiency,the paper studied the method of filtering temporary dynamic objects based on LiDAR:through improve Delaunay triangulations and clustering analysis,two methods were put forward,one was to filter the temporary dynamic objects based on the processing streaming Delaunay triangulations and the features of the temporary dynamic objects directly,and the other was to unite the Digital Elevation Model(DEM)and non-ground point without temporary dynamic objects.Experimental result showed the feasibility of the two methods.