Almost all e-commerce websites generates recommendations for their users but most of them are irrelevant. Collaborative filtering is one of the most widely used recommendation generation technique by e-commerce websites. Collaborative filtering generates recommendations for the target user from the collaboration of the other users who have the similar interest derived from their ratings. With the advent of the Web 2.0, web based social networks have become one of the major source of information. Users can now make friends, share thoughts, images etc. on the Internet and express different level of trust on their web friends. Recommendations generated by the trusted friends are more relevant than other users. This paper propose a book recommendation system that generates recommendations from the collaboration of trusted friends of the target user and uses association rule mining to capture current reading trend of users in the network.


Abstract : The fr ezing and hawing of water and blood in closed containers under conditions similar to those currently employed in processing blood is examine . The examination involved (1) the use of transparent containers, as well as containers with removable covers from which the frozen contents could be removed for visual examination; (2) measurement of the relative amounts of liquidAND SOLID AT VARIOUS TI S DURING PROCESSI G; AND (3) the use of thermocouples positioned in the containers. These obs rvations per it a detailed description to be made of the events occurring inside the container during freezing and thawing. This information has guided the development of blood processing equipment and techniques, and is gradually building up a background for subsequent mathematical analysis of the heat transfer problem involved. Some possible modifications to the type of agitation used during freezing are discussed briefly. These modifications, which reduce turbulence in the liquid being cooled, have possible advantages such as simplification of the type of equipment required. (Author)


To assess the utility of anti–melanoma differentiation–associated gene 5 (anti‐MDA5) antibody measurement for predicting a risk for developing rapidly progressive interstitial lung disease (RP‐ILD) in patients with polymyositis/dermatomyositis (PM/DM).


Background: Chronic lymphocytic leukaemia (CLL) is associated with global immunodeficiency, hypogammagobulinemia and T-cell exhaustion. We hypothesise that repairing T cell functions would improve cancer immune-editing, improve outcome and decrease infectious complications which cause significant morbidity in CLL patients.
 Chronic B-cell receptor (BCR) activation as well as close interactions with the tumour microenvironment promote survival of malignant CLL B-cells, supporting their ability to induce immune suppression. To date, the most clinically successful approach to BCR-signalling inhibition is by the use of BTK inhibitors (BTKi). It has been suggested that the BTKi Ibrutinib has the ability to modulate T-helper cell polarity from Th2 to Th1 and thus would be a step towards repairing CLL associated T-cell defects (1). We examined the impact of Ibrutinib on T cell function and immune phenotype in vivo in Eµ-TCL1 mice with CLL.
 Materials and Methods: C57/Bl6 animals 2.5 months of age were injected with 40x10e6 purified CLL B-cells pooled from Eµ-TCL1 mice with CLL. When peripheral blood CLL load reach >10% animals were randomized (mean day 14) to either vehicle treatment (2% HPBCD) or Ibrutinib treatment (0.15.mg/kg in 2% HPBCD) for 21 days. 17 animals per group were analysed. Splenic cells were isolated, the cellular component characterized by CyTOF and T cell function assessed by multi-parameter flow cytometry and T-cell synapse formation assay. We demonstrated that Ibrutinib administration this way led to high levels of BTK occupancy.
 Results: Treatment with both Ibrutinib resulted in increased expression of IL2 (p=0.0004) in CD4+ T cells and decreased expression of IL4 among both CD4+ T cells (p=0.0015) and CD8+ T-cells (p<0.0001). Interferon gamma production was reduced in CD4+ (p=0.0056) and CD8+ T-cells (p=0.0020) with Ibrutinib treatment, which also resulted in an increase in CD107a+/CD107a- ratio among both CD44+ (p=0.0002) and CD44- CD8+ cytotoxic T-cells (p=0.0463). Ibrutinib treatment increases T-cell synapse area (p<0.0001) (Figure 1). We find a trend towards less antigen experienced CD44+ T-cells with Ibrutinib treatment with decreased expression of PD-1 in both CD44+ and CD44- negative T-cells but more pronounced in the antigen experienced T-cells. (Figure 2A). In addition, decreased expression of immune checkpoint receptor KLRG-1 on antigen experienced CD44+ T-cells was observed, most pronounced in the CD4+ subsets (Figure 2 B). Among NK 1.1+ NK-cells we find a strong trend towards decreased expression of immune checkpoint receptor KLRG-1 (Figure 2C). In white pulp myelomonocytic splenocytes (WPMC) we find a shift away from Ly6c low macrophage/patrolling monocyte-like cells towards more Ly6C high inflammatory monocyte-like cells. Moreover, we find a trend towards decreased expression of PD-L1, which is highly expressed among Ly6c low cells and shows little to no expression among Ly6C high cells (Figure 2D).
 Conclusion: In vivo Ibrutinib treatment in this mouse model resulted in alteration in T cell function with cytokine secretion changes in keeping with a switch away from Th2 towards Th1 polarity as well as increased in cytotoxic T-cell function. The typical exhaustion phenotype of T-cell subsets is significantly ameliorated by Ibrutinib including a decrease in PD-1 expression. Moreover, we demonstrate a decrease in numbers of KLRG-1 high NK1.1+ NK cells. WPMC cells are shifted away from a potentially more tumour promoting Ly6C low PD-L1+ phenotype towards a more inflammatory Ly6c high PD-L1 low phenotype. These findings may point to a potential synergism of the combination of BTK inhibitors with immune checkpoint blockade for the treatment of CLL.
 References Dubovsky JA, Beckwith KA, Natarajan G, Woyach JA, Jaglowski S, Zhong Y, et al. Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes. Blood. 2013;122(15):2539-49.

 Gribben: Cancer Research UK: Research Funding; Celgene: Consultancy, Honoraria, Research Funding; Unum: Equity Ownership; Abbvie: Honoraria; Novartis: Honoraria; TG Therapeutics: Honoraria; Janssen: Honoraria, Research Funding; Acerta Pharma: Honoraria, Research Funding; NIH: Research Funding; Pharmacyclics: Honoraria; Wellcome Trust: Research Funding; Roche: Honoraria; Kite: Honoraria; Medical Research Council: Research Funding.


New math "pathways" would be required for non-STEM community college students. New math "pathways" would be required for non-STEM community college students.


The paper presents an information processing system for autonomously operating vehicles where engineers can write "publications" written in English that the autonomou s systems can "read" to acquire knowledge such as various skills and behaviour policies. Knowledge about how to perform feedback control based operations, how to do dynamical modelling, path planning, servo and tracking control skills, vision based feedback control, etc. can also be transferred. The "publications" are similar to engineerin g booklets with contents, sections, subsections in English, that can appear in HTML, LaTex(pdf) formats. The same paper's HTML file can be read by an agent on board the autonomous vehicle and after reading the paper the agent knows how to alter its control of the vehicle. There is no need for an application engineer to read a journal publication and implement it by programming, the research engineer's methodological work is directly utilized by the autonomous vehicle or robot. Engineers different from the author of the "publication" can also read the papers and learn the details of how the vehicle operates, how decisions are reached and how skills are performed. Not only will users of the autonomous vehicle clearly understand how it operates but will also know its limitations to avoid misuse or misunderstanding. Users can modify English sentences in the "publication" to influence the vehicle's behaviour or how its skills are performed.


Positive cubature rules of degree 4 and 5 on the $d$-dimensional simplex are constructed and used to construct cubature rules of index 8 or degree 9 on the unit sphere. The latter ones lead to explicit isometric embedding among the classical Banach spaces. Among other things, our results include several explicit representations of $(x_1^2+...+ x_d^2)^t$ in terms of linear forms of degree $2t$ with rational coefficients for t=4 and 5.


We report electronic and structural properties of cubic and hexagonal $3\mathrm{C}\text{\ensuremath{-}},\phantom{\rule{0.3em}{0ex}}2\mathrm{H}\text{\ensuremath{-}},\phantom{\rule{0.3em}{0ex}}4\mathrm{H}\text{\ensuremath{-}}$, and $6\mathrm{H}\text{\ensuremath{-}}\mathrm{SiC}$ bulk crystals and of the C-terminated $\mathrm{SiC}(001)\text{\ensuremath{-}}c(2\ifmmode\times\else\texttimes\fi{}2)$ surface as resulting from density functional theory (DFT) within local density approximation (LDA). In particular, we employ newly constructed nonlocal, norm-conserving pseudopotentials which incorporate self-interaction corrections. Results obtained with usual pseudopotentials show the typical LDA shortcomings, most noticeably the systematic underestimate of the band gap. These problems are attributed to an unphysical self-interaction inherent in the common DFT-LDA. We describe the construction of appropriate self-interaction-corrected pseudopotentials for Si and C atoms and show how they can be transferred to the $\mathrm{SiC}$ solid by adequate modifications. It is in the very nature of our pseudopotentials that they cause no additional computational effort, as compared to usual pseudopotentials in standard LDA calculations. To test their transferability to different crystal structures we apply these pseudopotentials to both cubic and hexagonal polytypes of $\mathrm{SiC}$. The resulting energy gaps are in excellent agreement with experimental data and the bulk band structures are in most gratifying agreement with the results of considerably more elaborate quasiparticle calculations. Structural properties of the different polytypes are found in excellent agreement with experiment, as well, not showing the usual LDA underestimate of lattice constants and overestimate of bulk moduli. Also the electronic structure of $\mathrm{SiC}(001)\text{\ensuremath{-}}c(2\ifmmode\times\else\texttimes\fi{}2)$, calculated to exemplify the usefulness of the pseudopotentials for surfaces, shows improved agreement with experiment as compared to the respective surface band structure obtained within standard LDA.


The MARPOL convention is one of the most important international conventions on marine pollution. It was the initiative taken under the flagship of IMO (International Maritime Organization) to curb down the pollution caused by ships and other carrier vessels in the sea. The convention majorly covers all types of pollutions and accidental and operational discharges of effluents into the sea. The core objective of the convention was to regulate, monitor and to measure the pollution caused in the sea and to bring the nation sates under a common umbrella to discontinue the ill practices which harmed the marine environment including both flora and fauna.


In this study, the aim was to obtain high bio-oil yields in a fixed bed tubular reactor at various pyrolysis temperatures, reaction times, sweeping gas velocities, particle sizes, and heating rates. In order to improve heat and mass transfer, a stainless steel basket was used. The raw material, olive residue, was placed into the reactor in two different ways:  directly and with a stainless steel mesh basket. It was proved that employment of the basket provided an effective heat transfer between the sample and reactor wall. As a consequence, higher volatile yields were observed. The maximum oil yield was achieved as 46.72% with a particle size of 0.85 < Dp < 0.45 mm, heating rate of 500 °C min-1, pyrolysis temperature of 500 °C, and sweeping gas flow rate of 400 cm3 min-1. It was concluded that reducing the residence time of evolved volatiles, minimizing the particle size, increasing the heating rate at a pyrolysis temperature of 500 °C, and improving the contact surface of raw material with the reactor wa...


This paper presents a new class of 8th order canonical polynomials in n-dimensional real space. Based on the sequential canonical dual transformation, all extrema are obtained. The method can be used to solve the associated 7th order nonlinear algebraic equations. Optimality conditions are provided to find both global minimizers and local extrema. Applications are illustrated by examples.


ICTs provide innovative means, not only for the dissemination of knowledge but also for the exploration of learning strategies that promote the construction of skills (Lebrun, 1999, CSE, 2000). Many professors who are beginning to be interested in ICT want to integrate them as tools to support their magisterial approach (Guay, 2002). Here, the professor takes advantage of ICT resources to significantly enrich his class presentations through multimedia presentations. Poellhuber and Boulanger (2001) speak of "interactive mastery". It is also about making documents available to students at all times, such as a website with links to EIDS. The present study was established with the aim of highlighting the utility of ICT in EEDD teaching at the core of the qualifying secondary school curriculum. The critical analysis of the curricular SVT curricula, and the statistical results allowed us to note that most teachers state that the use of ICT facilitates the construction of knowledge about EESD by students, and that the majority of them wish to benefit from continuous training to have a solid knowledge of Computer Science and to improve their practical ICT skills.


This is an article by Jennifer Schaus in Washington, DC and Mark Amadeo (Amadeo Law Firm) about JV's - Joint Ventures in Government Contracting. More and more contracts are being bundled and joint ventures, partnering and teaming are necessary strategies to staying alive in government contracting. Topics include but are not limited to Government contracting, B2G, govcon, Federal Procurement, Joint Ventures, JV, Teaming, partnering and Bundled Contracts.


In the context of globalization, exchanges between various countries and regions have become more frequent,
and cross-cultural communication skills have become very important. How to improve college students' cross-cultural
communication skills and what to do in the process of cultivating college students' cross-cultural skills are important topics
that schools and teachers need to explore in college English education. In actual teaching, due to the limitation of many
factors, the actual effect of cross-cultural teaching is not obvious, and there are still some problems. This article provides
some strategies and methods for eliminating cultural differences and cultivating college students' cross-cultural
communicative competence.


Platelet-rich fibrin (PRF) is platelet concentration that contains growth factors and acts as a biodegradable scaffold. The aims of this study were to determinethe quantity ofentrappedgrowth factors (Platelet derived growth factor BB, PDGF-BB) in the PRF and radiographically assess the stability of the fibrin in maintaining the lifted sinus space in minipigs. From the in vitro study, PRF was found slowly releasing thegrowth factor, PDGF-BB, during the ex-vivo period of 60 minutes, and the amount (1,963.93±380.17 pg/ml) was comparable to the total amount from immediate extraction either by physical (2,492.2±199.78 pg/ml) or chemical lysis (2,227.32±566.59 pg/ml).In vivo study, PRF wasable to be retained in the sinus of minipigs with minimal collapse during the first 2 weeks after application. PRF has been proven to be a source for growth factors and is able to be retained in the body during the initial period of wound healing.


In view of the uncertainty of groundwater pollution,velocity and dispersion coefficient and attenuation in river are considered as uncertainty parameters and expressed as gray parameters,and the gray numerical model of groundwater pollution is developed with gray systematic theory and numerical method and the method is given.The truncation errors in finite differential equation are corrected in solving the model.The typical solute transport equation of groundwater as an example is simulated with the gray model.The results indicate that the gray model can simulate the dynamic process in the absence of the information of hydrology and water quality.


Medical profession was unprepared to face the corona virus pandemic and the pharmaceutical
armamentarium is currently not robust enough to combat with SARS-CoV-2. Drugs that are used for other
medical conditions are also on trial to treat COVID-19. The pandemic is bound to pose psychological and
economical sufferings. Testing, treatments and vaccine are the three tools to combat with COVID-19. It is
feared that this viral infection would lead to an amplification of existing mental health issues and result in
a surge of cases of PTSD and depression. Senior citizens and people with compromised immunity becomes
more vulnerable to this toxic pathogen. A sound knowledge of all aspects of COVID-19 becomes essential
to deal with the aftermaths of this unprecedented pandemic and mental health professionals will have to
refresh their knowledge of virology and immunology. All the medical specialities will have to work together
to defeat the novel virus.


There is no single concept of a manufacturing system covering all industries in every detail. It is necessary to examine the fundamental properties and characteristics of a range of systems and to consider the way they are synthesized and operated before consolidating general conclusions. What is seen depends very much on the viewpoint and the narrowness of the focusing range. Nevertheless there is much to be gained from a fundamental study of-all aspects of manufacturing systems and their interactions since there are opportunities for technology transfer between industries Manufacturing systems must be designed by taking into account both steady state and-dynamic performance, whilst ensuring there is an adequate number of controllable variables to compensate the effects of uncontrolled disturbances. The technological process part of the manufacturing system is synthesized from interacting unit-operation subsystems, and this itself is a subsystem of the overall business system. The business system has a c...


Purpose – The purpose of this paper is to explore and engage with connections between the evolving technology of the Internet of Things (IoT) and notions of convenience. In particular, the concept of alpha convenience is introduced in order to articulate the broad scope of Internet "any-everything" connectivity, here called "alpha convenience." Design/methodology/approach – The recommendations of Constructive Technology Assessment are followed in order to evaluate technology before implementation. The seven value drivers articulated by Fleisch (2010) are utilized in order to envision-specific aspects. Findings – Three critical aspects relating to alpha convenience are identified and discussed: gossiping technology, personalization and the disempowered smartphone user. It is argued that extreme forms of convenience shift traditional areas of human agency onto technology. It is also noted that alpha convenience tends to develop as ubiquitous feature of future society, making it difficult, if not impossible,...


In order to study the problems that design process of inner cold twist drill is complicated,inefficient,the paper based on UG platform,combining UG/Open Menuscrip,UG/OpenAPI,UG/Open UIStyler and Visual C++6.0 redevelopment tools,builds a 3D model of a visual interface inner cold twist drill and selecting parameters of drill module.The paper has realized designer direct input design parameters and conditions by subscriber interface module in UG,in line with correspending three-dimensional entity model,accomplishing design of inner cold twist dirll,and improving designd efficiency,accuracy and reliability of inner cold twist drill.


The purpose of this paper is to describe ways to get main research sources when when we are making researcha in Library and Information Science, what skills are required for this. Some of the potential reseach resources to be used and evaluated are also described.


CuInSe2 powders synthesized by ball milling were printed on In2S3/TiO2/FTO/glass substrates, resulting in superstrate solar cells. Although particle structure of CuInSe2 in the layer remained after heating at 600 °C under N2 gas, photovoltaic effects were observed; the open-circuit voltage and short-circuit current density were 0.45 V and 5.6 mA/cm, respectively. The effects of annealing time on the structural, optical and photovoltaic properties of CuInSe2 were studied by scanning electron micrograph (SEM), X-ray diffraction (XRD), thermogravimetric analysis (TGA) and UV-Vis reflectance absorption spectroscopy. The CuInSe2 solar cells were printed in air ambient without vacuum processing and without toxic and explosive chemicals (e.g., hydrazine, H2Se and H2S), which can offer a promising strategy for future research and industrial investigation into costeffective photovoltaic systems.


In this research, nanostructured Ce0.8Zr0.2O2/Al2O3 composite catalysts were synthesized by a modified citrate complexation method with different loadings of active phase and support. The modification was carried out by impregnation and microwave-combustion techniques. XRD, FESEM, EDX, BET, FTIR and TPR-H2 have been used for characterization of nanocatalysts. Utilizing a microwave-assisted combustion method, we created a sample with a more uniform and homogenous pattern, leading to better catalytic properties and more available lattice oxygen toward CO oxidation. According to the reactor test, it was found that the support has a strong influence on the activity of the catalysts. Generally, between citrate modified by impregnation, addition of alumina up to 40 wt% enhanced the dispersion of the active phase and greatly improved the catalytic activity of the catalyst. The composition that performed the best in the reactor test was Ce0.8Zr0.2O2 (40 wt%)/Al2O3, which was synthesized by a citrate complexation microwave-assisted combustion method.


1. Artificially iodized blood serum (ox) causes acceleration of metamorphosis when fed to tadpoles, resembling that shown by thyroid, but not so marked nor so rapid.

2. It is possible to show by crude process of separation that the globulin fraction of the serum contains most of the substance with which the iodine combines to give the activity on tadpoles.

3. Alkaline hydrolysis of iodized proteins apparently destroys their activity, therein differing from thyroid. This suggests that the thyroid adds something to the iodine complex in the blood to complete the stable iodine containing thyroid hormone.


Abstact: An uniform Ni- P- nano- Al2 O3 coating was eletroless plated on 45 carbon steel, and the coating was then treated by high power CO2 laser beam with output power varying from 200 to 800 W. The surface morphology and the phase constituents of the coatings were observed and characterized by Scanning electron microscope(SEM) And X-ray diffraction(XRD) respectively. The micro-hardness and abrasion property and electrochemical corrosion behavior in 3.5%NaCl solution of the coatings were also examined.. The results reveal that with the laser power increasing the surface roughness of the coating decreases at first and then increases, and the quantity of nanoAl2 O3 on the coating surface decreases gradually. The as-plated Ni-P-nano-Al2 O3 coating is of amorphous structure. The phase transformation occurs from amorphous to crystalline after laser modification, the later consisted of crystallized phases of Ni and Ni3 P. The micro-hardness and wear resistance of the coating increases at first and then decreases with the increasing laser power. The corrosion potential of the laser treated coating shifts to a more negative value as the laser power increases, which implies a decrease of the corrosion resistance. The coating exhibits the best comprehensive property after the modification treatment with laser beam with power 400 W.


In the past osteoarthritis (OA) has been considered a predominately degenerative joint disease, affecting more
people than any other arthritis. However, it is now realised that the problem is not simply a degenerative
cartilage disorder, but a problem of all the tissues involved in maintaining joint stability - the functional joint unit. It is
characterised by progressive loss of cartilage and bony margin overgrowth. In addition, there is no doubt that
inflammation and synovitis are present in a significant percentage of patients, and indeed, a more aggressive form,
erosive osteoarthritis may occur, associated with significant synovitis, and may be confused with inflammatory arthritis, such as rheumatoid arthritis.


The paper analyze the need to improve the practical teaching system based on the characteristics of applied talents for clothing subject and teaching practice for Bauhaus University. The experience on Enterprise Practice Base in Fashion Institute, Zhongyuan University of Technology is summed up. Some improvement measures for further expansion of business practice are proposed in this article. Results shows that practice would be carried out in stages from understanding practice to graduation field work.


The investigation was conducted to develop the protein fortified mango RTS. Various proportions of soya protein isolate (SPI), peanut protein isolates (PPI) and rice bran protein concentrate (RBPC) were added to the mango pulp to fortify mango RTS. It was observed that there was progressive decrease in the sensory scores of the beverage with increase in proportion of protein concentrate in it. The ready to serve (RTS) beverage prepared by addition of SPI @ 1% followed by RBPC @ 1% showed maximum overall acceptability. Minimum acceptability was for RTS prepared by PPI. There was an increase in TSS, acidity, and non-enzymatic browning, while a decrease was observed in pH, ascorbic acid and crude protein contents of beverages during storage. However, microbial spoilage was not detected in beverages during storage. The soya isolate/milk fortified RTS scored relatively lesser with respect to control in organoleptic evaluation. The sugar replacement with fructose showed improvement in overall acceptability


"If space is infinite, we are anywhere, at any point in space." [1] (Borges, 1998, 91). If thinking is infinite, we may never stop sprouting thoughts. The main focus of this essay is the study of sonic art and to develop the new relationship between images and sounds. Instead of betraying the nature of thinking as a continuous motion, I decided to write in the same way as the mind thinks rather than disguised in any particular formation. I would consider the following blocks or texts or nodes or branches or sub-maps (whatever you like to call them) as a portrait that captures my ephemeral thoughts in a non-linear manner, in an effort to preserve their singular fluidity. Also, I would like to stress that the viewpoints here should not be perceived as something eternal, it should rather be considered as potential elements that enable further constructive conversation and possible trajectories for us to explore Sonic art.


Developments of technologies that facilitate vehicle connectivity represent a market demand. In particular, mobile device (MD) technology provides advanced user interface, customization, and upgradability characteristics that can facilitate connectivity and possibly aid in the goal of autonomous driving. This work explores the use of a MD in the control system of a conceptual electric vehicle (EV). While the use of MD for real-time control and monitoring has been reported, proper consideration has not been given to delays in data flow and their effects on system performance. The motor of a novel propulsion system for an EV was conditioned to be controlled in a wireless local area network by an ecosystem that includes a MD and an electronic board. An intended accelerator signal is predefined and sent to the motor and rotational speed values produced in the motor are sent back to the MD. Sample periods in which the communication really occurs are registered. Delays in the sample periods and produced errors in the accelerator and rotational speed signals are presented and analyzed. Maximum delays found in communications were of 0.2 s, while the maximum error produced in the accelerator signal was of 3.54%. Delays are also simulated, with a response that is similar to the behavior observed in the experiments.


We investigate the pseudoelastic behavior at room temperature of composite nanowires using molecular dynamics simulations. The nanowires are composed of a nickel core surrounded by a copper shell, leading to high coherency stresses. The coherency and surface stresses cause the nanowires to undergo a lattice reorientation, by twinning, from ⟨001⟩ to ⟨110⟩ during relaxation. Nanowires of different cross-sectional areas (varying from 2.17×2.17 up to 2.9×2.9 nm2) were studied. In all cases, under tensile loading, the nanowires reorient to ⟨001⟩ and then under unloading reorient back to ⟨110⟩, thus exhibiting pseudoelastic behavior. This behavior is more pronounced in composite nanowires with a coherent interface than for single crystal nanowires.


Vitamin D deficiency is suspected to cause possible complications in COVID-19 patients or they might be provided with a poor prognosis. However, this same vitamin D in excess is capable of causing toxicity. The presentstudy was based on a qualitative/quantitative study carried out from July to September, 2021 .Patients who tested positive for COVID-19 and who sought medical appointment in a private general practice in the city of Caçador,state of Santa Catarina (SC), were selected. The sample consisted of 54 patients who sought ambulatory care and who had a positive diagnosis for COVID-19. Vitamin D levels were found to beeither insufficient or deficient in most patients. However, the plasma concentration of vitamin D in these patients cannot be related to the positivity of the disease or hospitalization. What can be safely concluded is that vitamin D has numerous proven benefits, such as maintaining the cells of the immune system and, thus, preventing infectious diseases.


The article describes the causes of emergence and history of the concept Polycultural Education in the Russian pedagogy. Here I am giving the results of the analysis of the views of Russian scientists who participated in the conference Education and Interethnic Relationship (2009). I suggest using the periodization of the concept Polycultural Education connected with different means of the concept Culture in official Russian educational documents.


Thirteen types of business and sixteen administrative districts in Korea are categorized and segmented based on their similarities and visually plotted on multidimensional space. The similarities are determined by five characteristics of quantitative evaluation (simplified process of trading, reduced price, direct contact with supplier, faster process of trading, et cetera). Hence, domestic types of business and administrative districts can be categorized into certain clusters. Also, forms and characteristics of types of business and administrative districts can be evaluated between and within the clusters.


For over fifty years, scholars have argued that a therapeutic ethos has begun to change how people think about themselves and others. There is also a growing concern that the therapeutic ethos has influenced educational theory and practice, perhaps to their detriment. This review article discusses three books, The Dangerous Rise of Therapeutic Education (by Kathryn Ecclestone and Dennis Hayes), Aristotle, Emotions, and Education (by Kristjan Kristjansson), and The Therapy of Education (by Paul Smeyers, Richard Smith and Paul Standish), that point to the problematic assumptions and outcomes of therapeutic educational practices. The authors of the three books, however, disagree about whether a focus on emotions or therapy in education is necessarily an unwelcome intrusion into education.


Developing intelligent photosensitizers (PSs) responding to the tumor microenvironment (TME) to maximize the therapeutic efficacy and minimize side effects is a major problem for tumor phototherapy. In this paper, a dimethylamino (–NMe2)-functionalized boron dipyrromethene (Bodipy) derivative, namely, (E)-3-(4-(dimethylamino)styryl)-5,5-difluoro-2,8-diiodo-1,7,9-trimethyl-10-phenyl-5H-di-pyrrolo[1,2-c:2′,1′-f][1,3,2]diazaborinin-4-ium-5-uide (BDPIN) has been designed and synthesized by a Knoevenagel condensation reaction. BDPIN has a high singlet oxygen quantum yield (1O2 QY) of 74.8% in dichloromethane, and retains high 1O2 generation ability when nanoprecipitated in water with DSPE-PEG. For the synergistic therapy (photothermal conversion efficiency ∼28.6%), BDPIN NPs show a low half maximum inhibitory concentration (IC50) of 4.4 μg mL−1 towards human cervical cancer cells (HeLa). However, the dark toxicity of BDPIN NPs is almost negligible even at high concentrations. NPs with lysosome targeting ability can be triggered by the low acidity for enhanced phototherapy. Furthermore, an in vivo study demonstrates that NPs are able to inhibit tumor proliferation with laser irradiation, while causing no damage to normal tissues, suggesting the high phototoxicity, low dark toxicity and outstanding biosafety of BDPIN NPs. Results provide an approach for synthesizing nanomedicine in pH-activated enhanced phototheranostics.


Besides law, there are also other constraints regulating human behavior, namely norm, market and architecture. Each constraint has its particular way of effecting on the behaviors of men and the sum of these constraints consists the net of regulation in a society. According to Old Chicago School, "...


Ouray, Colorado, at 7800 feet, lies in a natural amphitheater in the northern portion of the San Juan Mountains. Mining and tourism are the primary industries; each fluctuating between boom or bust; mining erratically; tourism seasonally. The hot springs in the area average from 80/sup 0/ to 152/sup 0/F and discharge from 2 to 200 gallons per minute. The resource is probably associated with circulation along deep normal faults with a limestone aquifer dispersing the hot water. It is estimated that 2256 x 10/sup 11/ Btu's of geothermal energy are available in the area. The springs are used in a pool, and for space heating. An unsolicited proposal for additional resource assessment and engineering was rejected by DOE. An Appropriate Technology Small Grant was applied for, and an A and E subcontract is being applied for. Independent development is happening nearby in exploration drilling for space heating needs. The city will pursue a heating district scheme involving use of the pool spring, or drilling a well as funding dictates. The city has unique funding problems involving an unstable seasonal economy, desire to continue to maintain the hot springs pool, impatient citizenry, and nervous spa owners.


Badonnelia titei Pearman (Psocoptera: Sphaeropsocidae) was found in a laboratory building at Soldotna, Kenai Peninsula, Alaska. This is the first Western Hemisphere record of this domestic (i.e. dwelling in human habitations) species. The history of knowledge of this species is reviewed. ____________________ This note reports the first discovery of Badonnelia titei Pearman (Psocoptera: Sphaeropsocidae) in the Western Hemisphere. Data for the find are as follows. USA: ALASKA: Soldotna (N 60.461°, W 151.073°). Ski Hill Road, Kenai National Wildlife Refuge headquarters building. Crawling on floor of laboratory. 12 December 2005. M.L. Bowser. The material consists of a single well-colored female agreeing in form and color with prior published descriptions (Pearman 1953, 1958; Günther 1974a, 1974b; Lienhard 1998). Badonnelia titei is in the psocopteran family Sphaeropsocidae, which is unique in that females have elytriform forewings and lack hindwings, while males are completely wingless. Thus, the females resemble minute beetles, while the males look like book-lice of the closely-related family Liposcelididae. Sphaeropsocidae is represented by three genera and 15 extant species (Lienhard and Smithers 2002). Only B. titei is domestic in the sense of being known only from human habitations. Knowledge of this species has had an interesting history. The original description (Pearman 1953) was based on a single female kept alive in the hope that it would reproduce and augment the sample. It was found in the back binding of the loose cover of an atlas in the Zoological Museum, Tring, England. Subsequently, additional specimens were found in the same museum and a more detailed description, including both sexes, was published (Pearman 1958). Günther (1974a, 1974b) recorded the species from Belgium, Germany, France, and Switzerland, and noted that it is univoltine. By examination of digestive tract contents, he found that it feeds on fungal spores and body parts of (presumably) dead arthropods. Lienhard (1998) summarized the known distribution at the time, noting that it had been found in ten European countries (in addition to the five already noted, they were Finland, Ireland, Luxembourg, Norway, and Sweden). The European records of this species are mostly northern (see references listed by Lienhard and Smithers 2002). The southernmost record is from Geneva at just north of 46° N lat. From there it ranges north into Norway and Finland at localities north of 60° N lat. Although it is not clear how to interpret these distributional data for a domestic species in a biologically meaningful way, they suggest that the species may be expected in domestic situations in Canada and perhaps the northernmost portions of the USA. Badonnelia titei appears to be a member of a small cohort of psocids (and other Arthropods) known only from domestic situations, their natural habitats remaining undiscovered. It was not recorded in the entomological literature until 1952 (Beaumont, 1952, cf. Lienhard, 1977:470), when it was mis-identified as Embidopsocus enderleini (Ribaga). Thereafter it started to appear in the 1Department of Biological Sciences, Campus Box 4120, Illinois State University, Normal, IL 61790-4120. (email: firstname.lastname@example.com). 1 Mockford: First New World Record for Badonnelia Titei (Insecta: Psoc Published by ValpoScholar, 2005 212 THE GREAT LAKES ENTOMOLOGIST Vol. 38, Nos. 3 & 4 localities mentioned above. As several of the localities are natural history museums and other institutions devoted to zoological research (including the Alaska locality) its presence is interpretable in two ways: 1) personnel of such institutions are likely to observe and collect such obscure insects, and 2) these insects may have become introduced into these domestic situations with samples under investigation. Other species of Badonnelia are known from Chile, where they are found as free-living members of the soil fauna (Badonnel 1963, 1972). ACKNOWLEDGMENTS I thank M. L. Bowser for sending me the specimen for identification and for providing collecting data. I thank L. Brown, C. Lienhard, K. Yoshizawa, and an unknown reviewer for useful comments on an earlier draft of the manuscript.


G.I.S. processes for land use and development planning become important tools to manage data that allow the generation of optimal, real, concrete and high quality territorial models to support optimal decision making. This Thesis analyses the environmental dimension of the territory.
Planning requires good - diagnosis of geographic information. The processes and techniques of participatory data, qualitative and quantitative information that can be stored in geodatabases, in order to be analyzed technical and participatory way.
This Thesis uses information from the stakeholders of the territory, and generates territorial units by using GIS tools: "geodatabase management, spatial analysis and 3D modeling‖. Several categories were obtained, categories that identified environmental-ecological scenarios; some scenarios with problems or threat, such as: "land areas with slopes greater than 50%, known as very steep areas, with a high probability of landslides; or scenarios with potentialities such us ecological protection, for example: "areas with more than 3800 meters above sea level, described as moor; whose strength lies in storing carbon in its soil"....


individualized education program (IEP) team members throughout the country are struggling to make appropriate decisions regarding assistive technology (AT) for students with high incidence disabilities. Although numerous authors and organizations have developed tools to assist IEP teams when considering AT, the task can be overwhelming. Successful AT programs utilize preassessment, collaborative problem-solving, effective implementation, and systemic evaluation. Each of these issues present different challenges to special education teachers. This article is designed to simplify AT consideration for students with high incidence disabilities by highlighting several comprehensive resources that IEP teams can use to inform their decision-making process. Prior to our discussion of each resource, we identify barriers the IEP team may face when making AT decisions. It is our intention that the tools and resources presented herein should be used collectively by IEP teams to ensure that the AT needs of students with high incidence disabilities are addressed. The Individuals With Disabilities Education Improvement Act of 2004 (Pub. L. No. 108-446, Part A, Sec 602, pp. 11–12) defines an AT device as "any item, piece of equipment, or product system, whether acquired commercially off the shelf, modified, or customized, that is used to increase, maintain or improve the functional capabilities of a child with a disability." Federal law mandates the consideration of AT when writing a student's IEP. This means that it is a special education team's responsibility to ensure that AT is considered for all students, including those with high incidence disabilities. This task can be overwhelming due, in large part, to a critical shortage of AT specialists who help IEP teams make decisions regarding assistive technology for students with disabilities (Edyburn, 2004). Research indicates that members of IEP teams often have limited expertise regarding the types of AT that are available to students because of a lack of adequate training for preservice teachers entering the field (Cavanaugh, 2002). Despite this, there has been little to no increase by school districts in hiring AT professionals who can plan and supervise the effective implementation of AT (Edyburn, 2004). In some cases, experienced special education teachers have limited knowledge of basic types of AT (Puckett, 2004). Even special educators who strive to stay current in the AT field have difficulty ascertaining current, appropriate information from the diverse resources that are available. For example, a special educator conducting


The study evaluated therapeutic effects of aqueous and ethanolic extracts of Trianthema portulacastrum against carbon tetrachloride (CCl4) induced toxicity in rabbits. The entire sample plant was identified using key, dried, ground, and bioactive compounds were extracted using Soxhlet extractor. Adult rabbits (N = 60, 1 kg body weight) were divided into 5 groups: group I as controls, group II received CCl4 only, groups III to V received CCl4 in normal saline but were later orally administered different doses (75, 150 and 225 mg kg−1) of silymarin , aqueous or ethanolic extracts of T. portulacastrum. Hematological parameters were investigated 6 days after administration of the ameliorants. The effects of T. portulacastrum ethanolic and aqueous extracts were then compared to effects of standard silymarin drug. It was discovered that ethanolic extracts conferred hepato-protection on rabbits as silymarin did, suggesting that these extracts may be used instead of silymarin to improve animals health exposed to toxicity.


The case of a 32-year-old woman with a chronic polyneuropathy manifest as an anterior radicular syndrome is reported. Weakness evolved during a three-and-a-half-year period and was associated with high spinal-fluid protein, positive lupus erythematosus cells, and positive serum fluorescent antibody reaction. There was no evidence of systemic lupus. The possibility that lupus presents as an indolent disorder of nerve roots is suggested.


A microgrid including distributed generation sources (DGSs) is generally connected to a bulk power system to provide power to its local loads. The point of common coupling between the bulk power system and microgrid should meet relevant standards. The microgrid becomes a weak system with unbalanced and distorted voltages after it is disconnected from the bulk power system. A synchronisation controller for the DGS considering imbalanced three-phase voltages and harmonic voltages is presented. The proposed method can be implemented without altering the traditional phase-locked loop circuit. No filters and compensators are needed in the proposed method. Simulation results reveal that the proposed method is applicable.


This is a digest of all the papers published in peer reviewed journals that Professor Sir Michael Rutter (MR) has authored or co-authored up to 2020. I have also provided a brief commentary on the books he has authored or edited. I have not attempted to do the same for the book chapters that MR has produced. These are difficult to trace with any thoroughness and in many cases contain material that has been published in the papers and books that I have covered.


any computer programs for automatically determining which sense of a given context, according to a variety of semantic, defining or other types e EVALuation (SENSEVAL) is an open, community-based evaluation se Disambiguation (WSD) programs, arranged for a second consecutive he exercise is to be able to say which programs and methods perform beth words, or varieties of language, present particular problems to which ot only do we want to know which programs perform best, but also, the am want to know when modifications improve performance, and how nations of modifications are optimal. s, common words have more than one meaning. Usually, only one of in a given context, either written or spoken. This is no issue for people with others, but it is a difficult task for computers. The task is of great r of Natural Language Processing (NLP) applications, such as Machine oss-Language) Information Retrieval ([CL]IR). Word sense ambiguity r errors in such tasks and it is considered as thegreat open problem at . There are, however, several computer programs for automatically se of a word is being used in a given context, according to a variety of ictionaries. SENSe EVALuation (SENSEVAL), Kilgarriff (1998), Kilis an open, community-based evaluation exercise for Word Sense Disgrams arranged for a second consecutive time. xercise is to be able to say which programs and methods perform betwords, or varieties of language, present particular problems to which ot only do we want to know which programs perform best, but also, the m want to know when modifications improve performance, and how inations of modifications are optimal. Specifically for Swedish, we tigate to what extent WSD can be done, the potential resources availreate a framework that can be shared both within SENSEVAL and for ises of similar kind, national and international. SENSEVAL is designed . nt some of the experiences we gained by participating as developers ENSEVAL exercise for Swedish. Particularly, the choice of the lexical he annotation process, the scoring scheme, and the motivations for mple" branch of the exercise. first open evaluation exercise for WSD programs. Three languages French [5 systems] and Italian [2 systems]) and a total of 23 research NSEVAL-1 was held in Sussex, UK in 1998. The exercise was conworkshop: "Tagging Text with Lexical Semantics. Why, What and ashington. A range of Machine Learning algorithms and a variety of utilised. Two important points are worth to be mentioned w.r.t. s the fact that by the end of the exercise the purity of the approach was robustness of the system performance; and second, the discussion cremong the participants of how fundamental the lexicon is to the task. ified for SENSEVAL-2, these are: th lexical-sample , the all-wordsand n the lexical sample task, first, we sample the lexicon, then we find the sample words and the evaluation is carried out on the sampled -1 was a lexical-sample exercise). In the all-word task a system will be biguation performance on every word in the test collection. Finally, in


Flowers of Plumeria rubra, a mass-flowering tropical tree, share many traits with hawkmoth-pollinated flowers, and Plumeria pollen was recovered from the tongues of 17 hawkmoth species in Costa Rica. Rates of visitation and fruit set were exceptionally low compared with other hawkmoth flowers sympatric with Plumeria, apparently because Plumeria flowers produce no nectar reward. Hawkmoths in a flight cage quickly learned to avoid nectarless Plumeria flowers, but readily fed from these flowers after artificial nectar was added. Although no specific model for Plumeria was found in Costa Rica, the presentation of generalized odor and visual cues that mimic typical hawkmoth flowers may facilitate deceitful pollination of Plumeria. FLORAL MIMICRY ENCOMPASSES a diversity of reproductive strategies used by plants to achieve pollination by animals (see reviews of Wiens 1978, Little 1983). Because of experience with a model, pollinators visit a floral mimic expecting a reward. However, the mimic provides no reward and pollination occurs through deceit. Despite the importance of floral mimicry as a reproductive strategy, little detailed information about such systems exists (Wiens 1978, Williamson 1982, Little 1983). Williamson (1982) stressed that floral mimicry should be defined in terms of reproductive fitness. However, showing that fitness of a floral mimic is increased by its interaction with a model has rarely been successful in floral mimicy systems (Boyden 1980, Bierzychudek 1981, Williamson, pers. comm.). The essential difference in selection pressure on floral and insect mimics suggests that floral mimics may be less dependent upon resemblance to a model than insect mimics. Failure of an insect mimic to deceive a predator usually leads to the mimic's death, but failure of a floral mimic to deceive a pollinatory only results in the loss of potential pollination event. Deceitful plants may also attract pollinators by presenting cues that the pollinators innately recognize, rather than relying on strong resemblance to a model. In some instances a specific model may be absent (Dafni and Ivri 1981a, b; Ackerman 1981, 1983). In addition, convergence within floral syndromes may further complicate analysis of floral mimicry systems (Brown and Kodrik-Brown 1979, Williamson and Black 1981, Little 1983). In this paper I describe the floral biology of Plumeria rubra L. (Apocynaceae), a tropical tree apparently adapted for hawkmoth pollination. Plumeria produces no floral nectar and may be a generalized mimic of other hawkmoth-pollinated flowers. The reproductive biology of this species differs from typical examples of floral mimicry in that Plumeria lacks a specific model, is a massively flowering tree with an extended blooming period, and may be the most abundant hawkmoth flower in tropical deciduous forest of Costa Rica during much of its blooming period. STUDY SITES AND METHODS From 1976-1982 I studied Plumeria in northwestern Costa Rica (Guanacaste Province) at Hacienda La Pacifica, 10 km north of Canias, and at the Comelco ranch, centered 10 km north of Bagaces. The lowland deciduous and evergreen riparian forests at these sites (50-100 m elevation) are described by Frankie et al. (1974, 1983), Opler et al. (1980), and Opler (1983). I also made observations near the community of Monteverde (northern Puntarenas Province) from 1979-1982 where Plumeria grows in semi-deciduous, moist forest on the Pacific slopes at 800-1200 m elevation. FLORAL BIOLOGY.-Flowering phenology is based on Frankie et al. (1974) and my observations from 19761982. I studied the floral behavior of Plumeria using the methods of Haber and Frankie (1982) and Frankie et al. (1983). I monitored nectar secretion intensively on bagged flowers of two trees over several days and checked for possible nectar production on about 20 additional trees by probing flowers with microcapillary tubes and inspecting dissected flowers. I counted ovules in dissected flowers and seeds in mature fruits from the lowland site. Fruit numbers were easily observed on leafless trees during the dry season at


This dissertation is an historical inquiry into the concomitant transformations of architectural discourse and the discipline of architecture in America. It proceeds on the theoretical assumption that the documents produced and used in architecture not only reflect but constitute architecture as an institutional practice. The study begins with an outline of the academic discipline established, during the late nineteenth century, along the ideals of artistic autonomy and methods of the Ecole des Beaux Arts. It was an internalized discipline, centered on the self-referential discursive practice of the portfolio, and the integrated conceptual framework of composition, planning and the parti. During the latter half of the 1910s, with the changing conditions of architectural production, the traditional status of architecture began to be cast into doubt. In the aftermath of this crisis, what had once been an efficacious disciplinary formation was fragmented into the formal concerns of composition and the concept of functional planning as a rational intervention into social institutions. By the late twenties, ideological formations that made a fundamental break with the traditional claim to autonomy had emerged. The study examines two divergent strains of rationalist ideology: first, the new editorial policies of the architectural journals which projected in different ways, a rational discipline that would be integrated with the demands of mass production and consumer society; secondly, the Veblenian strategy of Frederick Ackerman, who attempted to isolate a domain of architectural discourse uncontaminated by the exigencies of capitalism. Two important transformations of architectural discourse that ensued during the thirties will be examined: the first was the shift in the status of the discourse of reference, constituted by the emergence of new types of reference manuals; secondly, the transformation of the architectural journal which saw the demise of the traditional status of the portfolio and its reorganization along studies of planning. At the center of these transformations was what I have called the discourse of the diagram. Through this new discursive formation, planning emerged as an integral discipline of architecture; it allowed the architect to intervene into the institutional program, while maintaining an independent method that was rational, free of formal preconceptions, and yet would produce singular results for each project. What had been a closed and tightly organized discipline was now opened and dispersed. Along with its promise of social amelioration, it carried the constant burden of formal invention. Thesis Supervisor: Stanford Anderson Title: Head, Department of Architecture; Professor of History and Architecture


INFLUENCE OF RESIDUAL SATURATION WITH WATER UPON THE RESISTANCE OF A WASHED-OUT ZONE OF WATER-BEARING SANDS

Summary
It has been shown experimentally (5), that about 5-10 per cent and sometimes more of the original connate water is not replaced by the mud filtrate in the invaded zone. It may lead to errors during quantitative interpretation of the results of the well log measurements. In the case, when this error caused by the presence of the original connate water in the invaded zone is not taken into consideration the determining value of the resistivity ρsp of the invaded zone for low mineralization is higher than the negative sing points to the fact, that the true value is lower (zone of negative errors shown in Fig. 2. The negative sing points to thef act, that the true value is higher than the apparent one). It leads to serious errors in computations of the coefficients of porosity and water saturation basing on the parameters of the invaded zone. The value of the error which was made by appointing ρsp is almost independent from the resistivity formation factor Pp. It depends only on the presence of the original connate water in the invaded zone and on the ratio ρf/ρwz. The coefficient of residual water saturation in the invaded zone can be calculated from the formula (10).


sus competition, group dynamics concerns of problem-solving approaches and phases, the problems of studying individuals' organizational roles, the organizational issue of the meaning and applicability of quality of work life interventions in the smaller organization, and the use of some sophisticated systems theory concepts in combination with small group development theory in order to design and carry out changes in a hospital. We even include a new professional is-


This paper presents a new method for fusion of medical images. It has been shown that 2-D wavelets are not sufficient for decomposition of images due to lack of directionality and shift variance. Complex wavelet transforms stand as a candidate to overcome deficiencies of wavelet transform. This paper exploits dual tree complex wavelet transform to decompose image and fuse the details and approximations based on maxima and averaging fusion rules. Results of visual and quantitive analysis prove efficiency of the method over conventional multiresolution methods in terms of mutual information, entropy and standard deviation.


applications implications The work presented in this thesis deals with quantification of pesticide emissions in the Life Cycle Inventory (LCI) analysis phase of Life Cycle Assessment (LCA). The motivation to model pesticide emissions is that reliable LCA results not only depend on accurate impact assessment models, but also good emission inventories. Recent LCA studies of agricultural products that take toxicity impacts into account show that pesticide emissions considerably contribute to toxicity impacts. At the same time, such conclusions are derived using a simplified approach to quantify pesticide emissions. The research presented in this thesis centers around PestLCI 2.0, a model to cal-culate pesticide emissions to air, surface water and groundwater for use in LCI. PestLCI2.0 is an updated and expanded version of the PestLCI model, released in 2006. The boundaries between ecosphere and technosphere in the model are defined by a 'technosphere box', which includes the arable land where the pesticide is applied, the field soil up to 1 meter of depth and the air column above the field up to 100 meter. When a pesticide leaves this box, it is considered an emission. The model works with a primary distribution, where the pesticide is deposited on the crop, on soil or emitted due to wind drift, followed by secondary processes that determine the pesticides' fate. In PestLCI 2.0, most fate process modelling has been updated, most notably the modelling of pesticide volatilization from leaves and pesticide runoff. The model was expanded by the inclusion of macropore flow, which leads to pesticide emissions to groundwater. Moreover, PestLCI 2.0s databases with active ingredients, climates and soils were updated, broadening the applicability of the model to European circumstances. A case study showed that emissions vary with variations in the climates and soils present in Europe. Emissions of pesticides to surface water and groundwater calculated by PestLCI 2.0 were compared with models used for risk assessment. Compared to the MACRO module in SWASH 3.1 model, which calculates surface water emissions by runoff and drainage, pesticide emissions to surface water calculated by PestLCI


THE CONTROVERSY ABOUT THE risks of fluoride is unlikely to be resolved soon, a meeting held in late July strongly suggests. Ever since fluoride was first added to water supplies in Grand Rapids, Mich., in 1945 to prevent tooth decay, the practice has been controversial. Some claim it does little or nothing to prevent tooth decay and is dangerous for health. Others, including most dentists and public health officials, say it significantly lowers rates of tooth decay and presents no important health risks. About two-thirds of the U.S. population drinks fluoridated water, and in recent years, when towns and cities across the country have held voter referenda on fluoridation, its use has been rejected about half the time. The status of the long-running debate over fluoride use and exposure was the subject of a citizens' conference held at St. Lawrence University, Canton, N.Y., on July 28-30. The meeting was organized by Paul Connett, emeritus professor ...


Alzheimer's disease is defined by its pathology, amyloid plaques, and neurofibrillary tau tangles, not by the clinical syndrome of dementia.


High school students with significant reading deficits must read to learn course content. A pilot study of Readable English, a phonics intervention providing embedded interactive orthography to scaffold online grade level content, increased both reading accuracy and reading comprehension compared to control group. Findings suggest this new learning intervention technology may particularly benefit students struggling to read and pronounce English at the word level. and regression analyses performed to determine the effects of improved on intervention group mean reading of .77 years, a mean net loss of -0.44 years for the control group; the control group. A regression analysis performed to fluency and BWRT


An important problem in communication engineering is the energy concentration problem, that is the problem of finding a signal bandlimited to [−σ, σ] with maximum energy concentration in the interval [−τ, τ ], 0 < τ, in the time domain, or equivalently, finding a signal that is time limited to the interval [−τ, τ ] with maximum energy concentration in [−σ, σ] in the frequency domain. This problem was solved by a group of mathematicians at Bell Labs in the early 1960's. The solution involves the prolate spheroidal wave functions which are eigenfunctions of a differential and an integral equations. The main goal of this talk is to present a solution to the energy concentration problem in a Hilbert space of functions. This solution will contain as a special case the solution to the energy concentration problem in both the fractional Fourier transform and the linear canonical transform domains. The solution involves a generalization of the prolate spheroidal wave functions, which when restricted to the fractional Fourier transform domain, we may call fractional prolate spheroidal wave functions.


Introduction Left ventricular assist device (LVAD) has garnered great interest recently for its remodeling reversal of end-stage heart failure (HF). However, recovery sufficient to permit device re...


The U.S. Advisory Committee on Immunization Practices recommends that rotavirus vaccine be administered to premature infants, who are at elevated risk


The current study explores how employee safety knowledge and behaviors are affected by employees' perceptions of management's concern for safety, perceived organizational ethics, perceived organizational support, and leader—member exchange. A field sample of 188 employees from several U.S. locations of a large multinational drilling company participated in the study. Results indicated that perceived organizational ethics, perceived organizational support, and leader—member exchange are indirectly associated with employees' safety knowledge and behaviors. The current study demonstrates that organizations should pay particular attention to the organizational context within which safety messages are transmitted. Differences in employee perceptions of this context may affect the effectiveness of the message. The findings also demonstrated strong support for a model linking perceptions of ethics, perceptions of support, and leader—member exchange as important mediating elements in the effective transfer of management's concern for safety to actual employee safety knowledge and behavior.


This note reports a small-scale survey of disclosures of free cash flow (whether described as such or not), examines one particularly complex disclosure as a case study of free cash flow calculation, and comments on the policy implications of the empirical findings.


The Yellow River frazil ice forecast system adopts the detection principle based on the differences in resistance characteristics of different media. The resistances of air,ice and water are acquired with the ice thickness sensor as information collection device to achieve real-time monitoring of the Yellow River frazil ice. The voltage signal and temperature signal are collected simultaneously by ice thickness sensor,with voltage signal processed into ice thickness and temperature signal used as auxiliary judgment. The ice thickness,water level and water temperature information uploaded to the monitoring center through the GPRS remote transmission module were obtained by choosing reasonable ice thickness judgment algorithm to analyze and calculate the collected data. The application results show that the excellent results have been achieved by this system in real-time monitoring of the Yellow River course section ice thickness and online forecast of beneath-ice surface water level,a large number of basic data have been provided for the Yellow River ice flood prevention work,and the system is applicable to the Yellow River ice flood prevention and disaster relief work.


Abstract In this paper we show that every module of a table algebra can be considered as a faithful module of some quotient table algebra. Also we prove that every faithful module of a table algebra determines a closed subset that is a cyclic group. As a main result we give some information about multiplicities of characters in table algebras.


Phenyl-substituted 1-arylazo-2-naphthols (AAN) display ···HNNCCO··· ⇌ ···NNCCOH··· ketohydrazone−azoenol tautomerism and can form intramolecular resonance-assisted H-bonds from pure NH···O to pure N···HO through tautomeric and dynamically disordered NH···O ⇌ N···HO bonds according to the electronic properties of their substituents. Three compounds of this series (m-OCH3-AAN = mOM; p-Cl-AAN = pCl; and p-NMe2-AAN = pNM2) have been studied by X-ray crystallography at four temperatures (100−295 K), showing that the remarkably short H-bonds formed (2.53 ≤ d(N···O) ≤ 2.55 A) are a pure NH···O in mOM, a dynamically disordered mixture in pCl (NH···O:N···H−O = 69:31 at 100 K), and a statically disordered mixture in pNM2 (NH···O:N···HO = 21:79 at 100 K). These compounds, integrated by the p-H-, p-NO2-, p-F-, and p-O--substituted derivatives, have been emulated by DFT methods (B3LYP/6-31+G(d,p) level) with full geometry optimization of the stationary points along the proton-transfer (PT) pathway:  NH···O and N···HO ...


It is widely acknowledged that the safety and quality of health care in the U. S. is not as high or consistent as it should be. As a result, health system leaders are being called on to improve the quality of care provided in their systems. Before effective strategies can be devised and implemented to improve conditions, however, they need to know exactly what the state of quality is in their systems. Only then can institutional leaders act effectively with knowledge to set specific goals they should attempt to reach and be able to assess the degree to which they have accomplished those goals. By "the state of quality" we mean (1) the extent to which care provided in a particular system meets established criteria for good quality care and (2) specific deficits that can be identified and act as targets for improvement.


According to Daniel Gile's effort model,in order to lighten the memory's burden,anticipation is of vital importance in simultaneous interpretation(SI).This thesis aims to analyze the importance,possibility and some basic ways of anticipation in SI.


This paper analyzes the reason of water resources waste in Longfengshan Irrigation Area in Wuchang and poses that water saving is the key of non_engineering measure and is the secondary of the engineering measure and the combination of this two methods to developing water saving agriculture.


This letter reports a novel synthesis method to design an extended dual-band power amplifier (PA). The proposed matching networks exhibit dual-band impedance rotation, leading the transistor to yield flat gain at the two designed passbands and suppressed gain responses at frequencies outsides the passbands. The fabricated PA represents a competitive solution in multiband and multimode applications as compared with the conventional dual-band PA based on the multifrequency techniques. The transistor CGH40010F from Cree is employed for verification. At 1.4 and 2.4 GHz, the bandwidth has been extended over 150 MHz at each individual passband. The implemented PA can deliver the saturated output power of 10 W minimum, and power-added efficiency of 65% minimum has been measured.


To the Editor.— Your compulsion to publish " JAMA 75 Years Ago" in each issue fascinates. Anyway, you have set me to browsing at the National Library of Medicine, to learn whether you or I might be missing some tidbits that we should know about. The issue of Sept 7, 1901 (37:638, 1901) contained an article that describes attempts to treat a child afflicted with diabetes mellitus. Physicians of the present generation should read that article or at least learn more about it and thereby appreciate fully the contribution made by Banting and Best.


Objective:To investigate the role of cytokeratin in determining the lymph node micrometastasis in node-negative gastric carcinoma with anticytokeratin antibody.Methods:Two hundred and forty-two dissected lymph nodes from 50 patients with node-negative gastric carcinomas were examined with hematoxylin and eosin(HE),antihuman CEA(carcinoembryonic antigen) antibody,anti-cytokeratin 19(CK19) antibody and anti-cytokeratin 20(CK20) antibody.Of them,28 patients were followed up for 48 to 90 months.Results: Micrometastases were identified in 11 of 50 patients(22%) and in 18 of 242 lymph nodes((7.44%)) by immunohistochemical staining.Positive reactions were found in 10 lymph nodes(4.13%) stained with CEA,and in 17((7.02%)) or 16(6.61%) stained with CK19 or CK20.No lymph node stained by HE showed positive result.A higher incidence of micrometastasis was found in the patients with recurrent disease((42.86%,) 3/7) compared with result from recurrence-free patients(9.52%,2/21).Survival analysis demonstrated that the disease-free survival time in micrometastasis positive patients was shorter than that of the negative ones.But there was no significant difference of the cumulative survival rate.Conclusions:CK is a more sensitive marker than CEA for detection of metastases,and the specificity of CK20 is better than CK19 in this assay.Micrometastases might correlate with worse prognosis for patients with histologic node negative gastric cancer.


The results of three different searches for neutrino candidates, associated with the IceCube-170922A event or from the direction of TXS 0506+056, by the ANTARES neutrino telescope, are presented. The first search refers to the online follow-up of the IceCube alert; the second is based on the standard time-integrated method employed by the Collaboration to search for point-like neutrino sources; the third uses information from the IceCube time-dependent analysis that reported bursting activity centered on 2014 December 13, as input for an ANTARES time-dependent analysis. The online follow-up and the time-dependent analysis yield no events related to the source. The time-integrated study performed over a period from 2007 to 2017 fits 1.03 signal events, which corresponds to a p-value of 3.4% (not considering trial factors). Only for two other astrophysical objects in our candidate list has a smaller p-value been found. When considering that 107 sources have been investigated, the post-trial p-value for TXS 0506+056 corresponds to 87%.


The article examines the cultural activities of commercial and rail assemblies as the main cultural centers in the Far Eastern cities, defines the role of culture in the daily life of citizens. Keywords: cultural life, cultural activities, assembly, leisure, city.


Existence of magneto-gravity waves (MGW) caused by substorm activity can produce a travelling ionospheric disturbances (TID) which velocities exceed sound. For MGW detection experimental data of oblique impulse ionospheric sounding for decameter range radio waves have been used. Mid-latitude and subauroral paths Inskip (England) - Rostov-on-Don, Cyprus - Rostov-on-Don, Norilsk - Rostov-on-Don and Irkutsk - Rostov-on-Don within weak geomagnetic disturbance condition are considered. Time delays between AE index of polar electrojets intensity and maximum observed frequency (MOF) for all paths are established. Among received time shifts 5-10 min values are marked. Such small delays answer to high-velocity disturbances which propagate faster then usual AGW. These cases can be connected to MGW propagation. Studying of index AE and registered MOF spectral structures for high correlation cases at small time delay shows a good agreement of spectrum features. At the same time a good agreement of spectral features for index AE and geomagnetic field horizontal components disturbances on ground magnetic stations takes place. According to calculated MGW dispersion curves their frequencies are equal to . () 4 12 1 0 H z ω − ≈− ⋅


Occasional super-saturation of river water with dissolved gases downstream of dams and other hydraulic structures is a well-known problem which can lead to large fish mortality up to several kilometres downstream. To explore the possibility and effectiveness of reducing the supersaturation by injecting air bubbles below the water surface, mass exchange process in a dilute liquid-bubble two phase flow is simulated using a computational model in which both time-dependent, three dimensional fluid motion and large numbers of bubbles are calculated in an Eulerian framework. The essay describes the necessary assumptions, its theoretical basis and its ability to simulate realistic length scales. In the analysis of the results, special emphasis is placed on the effects of initial bubble size and depth of bubble injector. Primary Reader: Prof. Andrea Prosperetti Secondary Reader: Prof. Rajat Mittal


The high level of human morbidity caused by E. coli O157:H7 necessitates an improved understanding of the infection dynamics of this bacterium within the bovine reservoir. Until recently, a degree of uncertainty surrounded the issue of whether these bacteria colonize the bovine gut and as yet, only incomplete in-vivo datasets are available. Such data typically consist of bacterial counts from fecal samples. The development of a deterministic model, which has been devised to make good use of such data, is presented. A partial differential equation, which includes advection, diffusion and growth terms, is used to model the (unobserved) passage of bacteria through the bovine gut. A set of experimentally-obtained fecal count data is used to parameterize the model. Between-animal variability is found to be greater than between-strain variability, with some results adding further weight to the hypothesis that E. coli O157:H7 can colonize the bovine gastrointestinal tract.


BACKGROUND
Sensor technologies are designed to assist independent living of older adults. However, it is often difficult for older adults to make an informed decision about adopting sensor technologies.

OBJECTIVE
To explore Bruce's framework of informed decision making (IDM) for in-home use of sensor technologies in community-dwelling elders.

METHOD
The IDM framework guided development of a semi-structured interview. A theory-driven coding approach was used for analysis.

RESULTS
Participants supported most of the elements of the framework, but not all aspects of each element were addressed. Perceived usefulness of technologies was identified as an area for framework extension.

CONCLUSION
This paper provides useful information for health care professionals to consider how to enhance IDM of older adults regarding the use of sensor technologies. The results also illuminate elements of the IDM framework that may be critical to facilitating independent living for older adults.


An equivalent model of a printed circuit board can be useful for simplifying electromagnetic problems, reducing the computational cost of numerical simulations. In this paper an equivalent model of a printed circuit board inside a metallic enclosure is evaluated inversely by means of simulations and measurements. In order to achieve this goal, results for a set of different printed circuit boards in three scenarios have been obtained. Benefits and drawbacks of the model are discussed. This equivalent model may be helpful when studying shielding properties of an enclosure protecting electronic devices.


Contents: The Allies and the Italian Social Republic: Uncle Sam, John Bull, and Ben - American and British Journalists, Intellectuals, and the RSI - Post-9/8 Prisoners of War.


Optical metamaterials have the potential to control the flow of light at will which may lead to spectacular applications as the perfect lens or the cloaking device. Both of these optical elements require invariant effective material properties (permittivity, permeability) for all spatial frequencies involved in the imaging process. However, it turned out that due to the mesoscopic nature of current metamaterials spatial dispersion prevents to meet this requirement; rendering them far away from being applicable for the purpose of imaging. A solution to this problem is not straightforwardly at hand since metamaterials are usually designed in forward direction; implying that the optical properties are only evaluated for a specific metamaterial. Here we lift these limitations. Methodically, we suggest a procedure to design metamaterials with a predefined characteristic of light propagation. Optically, we show that metamaterials can be optimized such that they exhibit either an isotropic response or permit diffractionless propagation.


A comprehensive spectroscopic and photophysical study of the keto and leuco forms of indigo and three other ring-substituted derivatives in solution was performed. The characterization involves absorption, fluorescence, and triplet-triplet absorption spectra, making it possible to obtain the quantum yields for fluorescence (F), singlet-triplet intersystem crossing (ISC), internal conversion (IC), and lifetimes for fluorescence (UF) and triplet decay (UT). For the case of the keto forms, pulse radiolysis experiments have revealed the existence of a triplet acceptor (from energy transfer from different donors) for the indigo, purple, and indirubin compounds. It is shown that with the keto form the major deactivation pathway involves internal conversion from the lowest singlet excited state to the ground state whereas with the leuco form there is competition between internal conversion, triplet formation, and fluorescence deactivation processes. Furthermore, leuco forms present much higher Stokes shifts compared with keto ones, suggesting an excitedstate geometry different from the ground-state geometry, possibly involving rotational photoisomerization.


The secondary development of ABAQUS finite element software have great promoting function for the application of ABAQUS in the engineering analysis.This paper introduces the basic principle and method of ABAQUS secondary development and illustrates the application of ABAQUS secondary development with examples of semisolid AZ 61 alloy compression shaping.It provides a new approach for further research into the thixotropic shaping mechanism of magnesium alloy and addition of new material model in the ABAQUS digital simulation.


Nanoparticle (NP)‐based drug delivery systems or nanomedicines have broadened the horizon of translational research for decades. Conventional bulk mixing synthesis methods have impeded successful clinical translations of nanomedicines due to the limited ability of the controlled, scalable production with high uniformity. Herein, an on‐chip preparation of self‐assembled, drug‐encapsulated polymeric NPs is presented for their improved uniformity and homogeneity that results in enhanced anti‐cancer effect in vitro and in vivo. The NPs are formulated through rapid convective mixing of two aqueous solutions of a hydrophilic polymer and an anti‐cancer drug, doxorubicin (DOX), in the swirling microvortex reactor (SMR). Compared to conventional bulk‐mixed NPs (BMPs), the microvortex‐synthesized NPs (MVPs) exhibit narrower size distributions and better size tunability. It is found that the improved uniformity and homogeneity of the MVPs not only enhance cellular uptake and anti‐cancer effect with pH‐responsive drug release in vitro, but also result in an improved tumor regression and decreased side effects at off‐targeted organs in vivo. The findings demonstrate that uniformly designed NPs with more homogeneous properties can induce a significant enhancement of an anti‐cancer effect in vivo. The results show the potential of a high‐speed on‐chip synthesis as a scalable manufacturing platform for reliable clinical translations of nanomedicines.


Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by /4.0) ABSTRACT Undergraduate students obtain creative knowledge and important skills by studying HTML5 in foundation of web programming and the principles underlying of HTML5 design and implementation. HTML 5 is the new and stylish standard for HTML. These topics build up students' clasp of the power of creation, help students and improve their design skills. Understanding web programming thus helps students in ways key to many profession paths and interests. HTML5 provides the students everything to create animation, music, movies and can also be used to build convoluted web applications and also carries cross-platform. HTML5 standard novices the development of real-time collaborations in web browsers, which conducts to less work for web developers.


Developing mobile software solutions in order to enhance learning in University environments by using the new mobile communication technology is becoming a very popular research focus. However there is a lack of research on the instruction method that should be used in the development of mobile learning software as a very important factor in the learning process and in the software engineering process. In this paper we investigate, develop and analyses a mobile software solution in using the Task Based Learning model. The research focuses on the developed software solution and reviews learning modeling approach focusing on task based learning that from the findings is concluded as the best approach for mobile learning. For testing purposes developed is a software prototype called M-Learn and its analyses has been investigated and recommendations for developing similar software solutions have been defined.


Fueled by a recent surge in sensing and artificial intelligence (AI), robotics has the potential to profoundly impact our daily lives. Indeed, with applications ranging from personal assistance and social companionship to inspection and search-and-rescue, the socioeconomic promise of this field is unquestionable. To accelerate the seamless integration of robots into our technology-driven society, our goal is to develop algorithmic foundations that will shape the way future generations of robots are made. More specifically, towards the goal of ubiquitous robots, our recent work focuses on customizability and accessibility by promoting an engineering meets AI methodology.


Different kinds of plasticizers and crosslinkers were used to prepare high-viscosity modified (HVM) asphalt and high-elastic modified (HEM) asphalt and the major physical properties were studied and compared. The kinds of plasticizers were optimized and the difference in composition between HVM and HEM asphalts was clarified. The plasticizers with different thickness and flexibility were available for HVM or HEM asphalts respectively. The kinds of crosslinkers were also compared and optimized and it was found that the most effective crosslinker was sulfur. The effect of anti-ageing reagent on HEM asphalt was confirmed and it was found that one of the most effective way to retain the properties of HVM and HEM asphalt before ageing was to increase the SBS content further. POLYM. COMPOS., 2015. © 2015 Society of Plastics Engineers


Ferrocene and its derivatives reveal many special properties and they have been used in many areas.Nitrogen-containing heterocyclic ring compounds have good biological activities,especially,the 1,2,4-triazole derivatives have been given much attention in recent years.In order to evaluate the cytotoxic activity of ferrocene Schiff base in this paper,six novel ferrocene Schiff bases were synthesized through the reaction of ferrocene carboxaldehyde with 3-substituted-4-amino-1,2,4-triazole-5-thione and four new ferrocene acylhydrazone Schiff bases were also synthesized through the reaction of ferrocenecarboxaldehyde or acetylferrocene with acylhydrazine.Their structures were characterized by 1H NMR,IR,MS and element analysis.Their cytotoxic activities were evaluated in vitro by an 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay using human cervical cancer cells(Hela) and the results show that these compounds exhibited some cytotoxic activities against cancer cells.In addition,the results indicate that compound 2 presented stronger cytotoxic activities against cancer cells(Hela) than compound 4.


Pest control device (23) includes a having a first critical surface tension value is a first substantially impermeable surface (20). Volatile pest control agent, this is applied to the first surface (20) on, at least about 5 dynes / cm


Summary form only given. Software for systems biology has been under development since the 1950s and has accelerated considerably in the last five years. However, much of the development has been repetitive and there has been little genuine innovation. In this talk I wish to briefly discuss the history of software provision in systems biology and will try to address the question why the academic community has found it so difficult to innovate. In many cases the software developed today is little different in functionality from the first packages that were written in the 1950s. Ironically is it industry that seems to be taking the lead. In particular, Microsoft is funding new theoretical developments at their systems biology centers and Math Works has developed a substantial dynamics software package (SimBiology 2.0) for their Matlab product


Sliding-window random linear network coding (RLNC) is a good fit for achieving low in-order delivery delay in future-generation networks characterized by lossy links. In high bandwidth-delay product networks, however, the issue of integrating RLNC with transmission control protocol (TCP) flow and congestion control poses a significant challenge. In this paper, we propose an innovative reinforcement learning (RL) framework that addresses this issue by decoupling the RLNC sliding window from TCP and dynamically adjusting it to enhance network performance in terms of goodput, in-order delivery delay, and decoding complexity. By employing RL, we enable autonomous decision-making for adjusting the sliding window of RLNC, which operates independently of TCP. This decoupling allows RLNC to adapt dynamically to the varying conditions of the network, without prior knowledge of its characteristics. By leveraging the benefits of RLNC and TCP separately, we achieve more efficient and effective utilization of network resources. The results highlight significant improvements in goodput, in-order delivery delay, and decoding complexity. These improvements are crucial because in network coding, there is always a trade-off between goodput, delay, and decoding complexity, and minimizing this trade-off is very challenging. Using RL and decoupling of RLNC sliding window from TCP, we address this challenge and minimize the trade-off significantly. Goodput is improved by up to 11%, the in-order delivery delay is reduced by a factor of 9%, and coding complexity shows an improvement of up to 45% compared to the state-of-the-art.


Objectives: To assess the association between hyperuricemia and different neuropsychiatric manifestations and stroke risk factors in systematic lupus erythematosus (SLE) patients. Methods: This study was conducted on 204 SLE patients who were admitted to a tertiary referral center. A standardized questionnaire was completed for all the participants and the medical records were reviewed regarding the occurrence of arterial or venous thrombotic events, stroke, seizure, depression, headache, psychosis, and peripheral neuropathy. In addition blood samples were drawn to obtain serum uric acid, triglyceride (TG), highdensity lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, and total cholesterol levels. Results: Hyperuricemia (serum uric acid ≥6 mg/dl for women and ≥7 mg/dl for men) was detected in 16.1% of SLE patients and was significantly associated with the occurrence of stroke (OR, 2.38; 95%CI, 1.2–7.24), and peripheral neuropathy (OR, 3.49; 95% CI, 1.52–12.23), independent of hypertension and hyperlipidemia. Hyperuricemia was also significantly associated with hypertension (OR, 7.76; 95% CI, 2.72–15.76), hyperlipidemia (OR, 5.05; 95% CI, 1.59–11.32), and history of arterial thrombosis (OR, 4.95; 95% CI, 1.98–15.34), independent of age and body mass index. Conclusions: Hyperuricemia in SLE patients is independently associated with the occurrence of stroke and peripheral neuropathy. It is also independently associated with hypertension, hyperlipidemia, and history of arterial thrombosis, which are the major stroke and myocardial infarction risk factors in SLE patients. © 2015 Elsevier Editora Ltda. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). ∗ Corresponding author. E-mail: email@example.com (S. Movassaghi). ttp://dx.doi.org/10.1016/j.rbre.2015.07.011 255-5021/© 2015 Elsevier Editora Ltda. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ icenses/by-nc-nd/4.0/). 472 r e v b r a s r e u m a t o l . 2 0 1 6;5 6(6):471–477 Hiperuricemia no lúpus eritematoso sistêmico: está associada a manifestações neuropsiquiátricas da doença? Palavras-chave: Neurologia Neuropatia Lúpus eritematoso sistêmico Acidente vascular encefálico Ácido úrico r e s u m o Objetivos: Avaliar a associação entre a hiperuricemia e diferentes manifestações neuropsiquiátricas e os fatores de risco para AVE em pacientes com lúpus eritematoso sistêmico


The sheer magnitude of the black diamond trend suggests that marketers ignore it at their own peril. There are enormous opportunities available for those who are astute, flexible and willing to change their marketing mantras. Immersion and imagination are probably the two major keys for effectively engaging with and tapping into this market.


A high-concentrated compound organic liquid fertilizer is a chemical mixture containing refined humic acid, base elements, auxiliary elements, trace element, chalating stabilizer, activator, promoter, balance amendment and wetting agent, and features easy and quick absorption, increasing yield, improving quality, increasing resistnce to disease and pests, saving base fertilizer, no poison and no pollution.


Objective To discuss the clinical features,diagnosis and treatment of metastatic adrenal carcinoma.Methods Data of 32 cases of adrenal metastasis admitted during Mar.1995 to Dec.2010 were analyzed retrospectively.21 cases were surgically treated and 11 cases gave up operation.Results Of the 21 cases which received operation,16 survived for an average of(28.6±6.5) months.Of the 11 cases without surgery,8 cases were followed up,with an average survival of(10.3±3.2) months.Conclusions Ultrasonography and CT are important diagnostic methods for metastatic adrenal carcinoma,which can be treated with surgery for long-term survival.


To study the treatment of penetrated retinal detachment by combined surgery of vitreous, retina and silicone oil tamponade retrospectively. Methods The patients had undergone surgery of vitrectomy,membrane decollement, underwater coagulation, retinal incision, intravitreous silicone oil tamponade. Some patients had undergone scleral encircling at the same time. Results 77 eyes (78.57%) of totally 98 eyes had got good retinal reposition. 67 eyes had been followed up.50 eyes (74.65%) of them had on retinal re detachment occurred. 43 eyes(64.18%) restored a visual acuity of better than counting finger. 14 eyes (20.90%) better than 0.05. 12 eyes (17.91%) better than 0.1. Conclusions Combined surgery had a better result for penetrated retinal detachment. It could be a good method for the patients who could not be healed by other regular methods.


The first step of debugging a deployed application is to reproduce the reported bug. But bugs that cause unpredictable behaviors without crashing the applica- tion can be difficult to reproduce, be ...


The general principles of operation of the swept frequency acoustic resonant interferometer are outlined and its use for measurements of energy loss and velocity dispersion in the low megahertz frequency range discussed. A number of different variations on the design of the resonator are described. Data on a variety of chemically different systems are presented illustrating the range and versatility of the technique for measurement of samples with low acoustic losses.


Automated image clustering/classification is a task of considerable importance. To apply this task to remotely sensed imagery, the authors have pursued an unsupervised clustering scheme based on principles of robust (statistical) estimation. A description of the module employed and results obtained are provided.


Research was studies of Golgi apparatus an organelle in most eukaryotic cells. The research question was does process RNA constituents of enzymes for the apparatus. Method involved sort of cells production and selection for distribution. A specialized determination indicators known as phosphate were inclusion by enzymes. Results indicated cisterna was a membrane in Golgi apparatus. This consisted three to twenty membranes. This cisternae was between the interior and outside environment. This organelle determined the substances in and out of cells. It can be concluded the covalent attachment to the membrane after its synthesis by A promoter. The cisternae were 15000 to 250000 Daltons in the cellular substances production of the plant.


The divorcing of moral responsibility from the practicalities of engineering in this modern age endangers both society and the professional status of engineers. In this, the fourth article in our series on `Engineering and Society? some of the issues of which today's engineers should be aware are considered


China is in a period of rapid urbanization. Due to the high concentration of population 13 and industries, the loss of flood and waterlogging has become more and more serious. Therefore, it 14 is of great significance to strengthen the analysis and evaluation of the the losses of flood and 15 waterlogging disasters in China for the recent years. This study analyzed of the losses caused by 16 flood and waterlogging disasters in China from 2006 to 2017. The results show that it is the most 17 serious year affected by floods and waterloggings in 2010. However, the relationship between 18 rainfall and flood disaster losses is not significant, which may because the occurrence of flood 19 disaster is the comprehensive effect of many factors. From the spatial distribution, it shows the 20 eastern and southern parts of China suffer a greater losses from the flood and waterlogging disasters. 21 Because these areas are more vulnerable to floods and waterlogging disasters under the impact of 22 both monsoon and typhoon. The study is hoped to provide some reference for flood disasters 23 control and disaster mitigation in the future. 24


The motivation of this work is to understand the effects of tool properties and downfeed (or infeed) method on the planarization of a patterned Si wafer. In oxide or interlevel dielectric (ILD) planarization process, the major concerns are the global planarity, oxide thickness differences in different regions across the chip and the remaining local step height (or height differences in oxide over the patterned features and between pattered features). By extending the MIT density-and-step height dependent model, this paper aims to establishing an analytical model to incorporate the tool stiffness and infeed scheme. A 2D simulation has also been performed to show the model validity and the effects of tool stiffness and infeed scheme on the planarity of wafer.