The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic requires treatments with rapid clinical translatability As such, several studies have screened FDA-approved drugs in silico at a limited number of classical antiviral sites for anti-SARS-CoV-2 activity We hypothesized that an extensive in-silico drug repurposingscreen against a wide range of SARS-COV-2 proteins could identify novel antiviral drugs and help elucidate mechanisms of drug action of hits from in vitro screens We selected 48 known or predicted drug sites across 23 SARS-COV-2 proteins using homology models and crystal structures based on known antiviral drug sites (i e , polymerase or protease active sites), computational predictions, and protein-protein interfaces Then, using the software GOLD, we docked 1268 FDA-approved small-molecule drugs into each site Virtual hits were prioritized based on their anti-SARS-COV-2 activity found in a recent phenotypic drug-repurposing screen using human huh-7 epithelial cells This resulted in the identification of a range of drugs acting at a variety of targets and sites Several compelling drug/site pairs were identified, including sites on the Spike protein, which mediates viral entry For example, we identified hits with anti-SARS-CoV2 activity in vitro, at a putative allosteric site that incorporates two functionalities required for viral entry, namely the Spike S2? cleavage site ? which a host protease must cleave for viral entry, and the critical ?fusion peptide? domain ? which injects itself into the host membrane during viral entry Moreover, these in silico results identify possible mechanisms for in vitro drug repurposing hits, potential additional targets for known drugs, and a starting point to test drug combinations that may have better activity by acting at different steps in the viral cycle activity in combination than on their own 8 5 5


The measurement system of the gas-operated underwater gun includs the pressure and velocity measurement system.The strain pressure measurement sensor and the induction velocity measurement sensor are used to measure the pressure of bore and gas chamber and the velocity of automatic mechanisms respectively.This paper gives some experimental data gotten and makes analyses about the experimental phenomena to provide criteria for dynamic analysis of underwater gun.


or other chaos end, countries need to address the root causes of the conflict to make the fragile peace sustainable. In this context, countries need to establish public security; to create participatory political systems with good governance and respect for the rule of law and human rights; to restore social cohesion; and to construct functioning economies that enable ordinary people—including the youth and uneducated—to have jobs and to earn a decent and licit living. Table 1 enumerates the challenges of this transition.1 The fact that the economic transition—also referred to as "economic reconstruction" or the "economics of peace"—takes place amid this multifaceted transition and not independently from it makes it fundamentally different from "development as usual." The experience of the last two decades has shown that war-torn countries cannot move into sustainable long-term development unless they engage first in the economics of peace—an intermediate and distinct phase which must aim at reactivating the economy while simultaneously minimizing the high risk of relapsing into conflict.


The chapter outlines a view of our knowledge of our actions on which it is – like our knowledge of our beliefs – authoritative, relatively a priori and relatively transparent. A number of possible accounts of our knowledge of our actions are canvassed, and it is argued that they are in tension with those features of such knowledge. The paper concludes by presenting a brief account of how we might explain our knowledge of our actions as knowledge by participation.


We study emptiness formation probability (EFP) in interacting 1D Bose liquids. That is the probability that a snapshot of its ground state reveals exactly zero number of particles within the interval $|x|<R$. For a weakly interacting liquid there is parametrically wide regime $n^{-1} < R <\xi$ (here $n$ is the average density and $\xi$ is the healing length), where EFP exhibits a non-trivial crossover from the Poisson to the Gaussian behavior. We employ the instanton technique [A. Abanov, 2004] to study quantitative details of these regime and compare it with previously reported limited cases.


A multiwideband bandpass filter (MW-BPF) using a quad cross-stub stepped impedance resonator (QC-SSIR) was simulated, fabricated, and measured. The proposed QC-SSIR is designed on a four-series arrangement of crossed open stub (COS) structures where each open stub is developed with a step impedance resonator (SIR) structure to generate a wide bandwidth. Compared to the COS resonator, the QC-SSIR has a wider fractional bandwidth and good transmission coefficients and is compact. ABCD matrix analysis is used to investigate the filter structure. Furthermore, the MW-BPF is designed on an FR4 microstrip substrate with εr = 4.4, thickness h = 1.6 mm, and tan δ = 0.0265. The results show that the proposed MW-BPF using a QC-SSIR achieves transmission coefficients/fractional bandwidths of −0.60 dB/49.3%, −1.49 dB/18.7%, and −1.93 dB/13.9% at 0.81 GHz, 1.71 GHz, and 2.58 GHz, respectively. Furthermore, to reduce the filter size, a folded QC-SSIR (FQC-SSIR) structure was also proposed. The results show that the proposed MW-BPF using an FQC-SSIR achieves transmission coefficients/fractional bandwidths of −0.57 dB/49.6%, −1.21 dB/17.7%, and −1.76 dB/12.5% at 0.82 GHz, 1.80 GHz, and 2.62 GHz, respectively. The size of the proposed MW-BPF using an FQC-SSIR is reduced by up to 46% compared with the MW-BPF using a QC-SSIR. Finally, the performance of the simulated MW-BPF based on the QC-SSIR and FQC-SSIR was in good agreement with the measurement results.


The aim of the article is to provide a brief analysis of the influence of intergovernmental transfers on subnational government behavior and provision of services. The article attempts to integrate both the theoretical and empirical insights through fiscal federalism literature and from empirical studies. The article examines the effects of two basic types of transfers on provision of public services by using the indifference curve analyses. The article also describes the basic principles of grant design, and analyses fiscal discipline in accordance to dependence on intergovernmental transfers.


Housing America's Elderly is not nor was it meant to be a prescriptive guide for older persons. Golant's master assumption that the many complexities and confusions associated with the various housing/care possibilities may render older consumers unable to make adequate choices seems questionable, however. Consumers of all ages in our consumer-oriented society potentially have an almost unlimited variety of goods and services from which to choose. Moreover, many sets of goods and services have numerous pros and cons associated with them―a la products discussed and rated in Consumer Reports. In the case of a particular good or service, however, most consumers have very few real choices-without necessarily being psychologically traumatized or even concerned by that fact. Consider motor vehicles (not to mention computers, VCRs, cable television, long-distance calling services, colleges and universities, even housing, and ...). There must be hundreds of models of cars and


Numerous female workers underwent a beginning of sexualization in an experimentally orphaned colony of the Neo‐Guinean termite N. princeps (Desneux). This led to the development of intercastes, displaying variable mosaics of worker, nymph, and soldier characteristics. The developmental pathways of these intercastes were studied with the help of multivariate techniques that revealed two main lines, one ending in a new "giant soldier" morph, the other proceeding toward the differentiation of nymphal characters, i.e., wing pads and compound eyes. It is not known whether these individuals might ultimately have become functional. Precocious adults resulting from a shortened nymphal course were also present, and one young replacement queen had already begun laying eggs.


Reactions of potassium oligosilanyls with ZnCl(2) lead to the formation of oligosilanylzinc compounds with zinc's coordination sphere expanded by ligation of TMEDA, an additional oligosilanyl group, or a chloride ion.


The MIV and MV absorption spectra of Er2O3 have been studied in detail and a careful comparison made with the M?, ? emission lines. The MV absorption spectrum possesses a number of well-defined absorption maxima. It is shown that the minima between these maxima coincide closely with components of the M? multiplet and it is suggested that the main components of the emission line previously observed by Van der Tuuk and by Lindberg are not real but are produced by self-absorption in the target material The line is probably accompanied by one or more real satellites however. The MIV absorption spectrum is much weaker, but probably possesses a number of maxima also. The M? emission line probably possesses a satellite, but its form appears to be influenced by self-absorption.


The rapid growth of demand for poultry products requires its sufficient production by specialized farms of various forms of ownership. However, such production needs are not always adequate to the selection approach, the incubation component, the basic requirements of veterinary and sanitary and zoohygienic support, breed and age characteristics of keeping and raising poultry. Therefore, one of the crucial components of obtaining biologically complete, high-quality and fast-paying products of the poultry industry, including all stages of its production, is human support of the main links of ontogenesis (development after birth) of the bird. The issue of not only the creation of the genetic potential of the parent bird of different species and areas of productivity, but also the provision of veterinary and sanitary conditions for their maintenance, breeding and breeding remains relevant. However, the current economic conditions have forced the heads of enterprises and veterinary departments to some extent bypass the planned laboratory tests of feed, water and blood, which, although not complete, but informative enough to trace the main periods of growth and development of the bird. Slight deterioration of the mode and quality of feeding, changes in the parameters of the microclimate are reflected in changes in blood parameters. And what about the spoilage of feed, water, violation of veterinary and sanitary maintenance of poultry: the lack of preventive treatments with vitamin-mineral, hepatoprotective and enzyme preparations, pre- and probiotics. Which can lead to metabolic disorders in poultry. Which can occur due to disorders of protein, lipid, carbohydrate, vitamin, macro- and micromineral metabolism. As a result, there are significantly popular diseases such as: uric acid diathesis, cannibalism, osteoporosis and osteomalacia, perosis, rickets, obesity, E-hypovitaminosis. Further reducing productivity, which leads to large economic losses on farms.


The minimum cost in a cylindrical filter high bandwidth are achieved when the ratio of the height of the housing to a diameter equal to 4.5. In this case, the height of the cylindrical filtering devices in the form of molded products is 65% of the height of the filter housing that will lead to an increase in the size of the room required for its extraction and consumption of thermal energy for heating the additional portion of the premises distributing unit. In order to reduce the consumption of materials and total cost in the location of the cylindrical filtering devices, according to the patent № RU 158000 U1 with priority from 16.12.2014, proposed to install several filtration devices placed on one another. The article proposes a mathematical model to determine the optimal number of filtering devices, which correspond to minimal additional costs in them and the room to accommodate them. It is proved that the control parameter of the proposed mathematical model is the number of the filtering devices because it expresses a contrary influence on the value of capital investments and operating costs in their production, installation and dismantling, on the one hand, and on the other hand in the segment of space that is needed to extract the filter devices. The results of calculations showed that, for example, for a filter with the diameter of inlet and outlet pipes 350 mm, located in the gas control unit, the optimal number of filter device is three pieces.


The total DNA of Trichoderma viride was extracted with the classical CTAB method,simplified CTAB method,benzyl chloride method and a rapid DNA extraction method.A pair of primers were designed and synthesized according to the sequence of CBH2,the CBH2 gene fragment was amplified with PCR,using the DNA extracted with the methods above as template.The result showed that the simplified CTAB method was the best method for the extraction of PCR template of Trichoderma viride.


Although large studies on sex chromosome abnormalities have not detected a higher incidence of malformations in 47,XYY males, several case reports suggest that there is an association between renal agenesis or cystic dysplasia of the kidney and XYY status. The authors report 3 further infants with XYY karyotype who had urogenital malformations leading to Potter sequence. On the basis of our observations and review of the literature, we suggest that the XYY syndrome and Potter sequence are more significantly associated than expected by pure coincidence.


Measured propagation loss for capacitive body-coupled communication (BCC) channel (1 MHz to 60 MHz) is limitedly available in the literature for distances longer than 50 cm. This is either because ...


This study was conducted to express exogenous s-galactosidase and make lactose hydrolyzed in mammary epithelial cells which could provide a valuable way for obviate lactose intolerance. PCR was used to get the 5' flanking regulatory region of bovine alpha S1 casein gene (1.2kb) from the genomic DNA and construct the vector. s-galactosidase was expressed under the control of 5' flanking regulatory regions of bovine alpha S1 casein gene (1.2kb) in caprine mammary epithelial cells (CMECs). LacZ gene expression specificity was detected by 5bromo-4-chloro–3-indolyl-s-D-galactoside (X-gal) staining of the s-galactosidase activity. In the cell culture supernatant and cell extracts, s-galactosidase was detected within 24 to 144 h after transfection. s-galactosidase of the cell extracts had a gradually decrease tendency in 24 to 72 h. In contrast, s-galactosidase of cell culture supernatant had a gradual increase tendency. In the cell extracts, s-galactosidase could be detected in 1 to 3 generation. HPLC showed that the lactose concentration of CMECs was reduced by s-galactosidase and the effects held significantly in 24 to 144 h posttransfection. s-galactosidase could express in CMECs and significantly reduced the lactose concentration of CMECs, these findings would provide an available way for obviate lactose intolerance.


In this paper,peroxidase(POD) and esterase(EST) in the leaves of male and female plants in Asparagus officinalis L.were comparatively analyzed by using polyacrylamide gel electrophoresis(PAGE) and biochemical staining.The results indicated that the patterns of POD and EST isozyme were obviously different in male and female plant.The male-plant had another band(Rf=0.78) of POD and another band(Rf=0.93) of EST,which did not exist at all in female-plant.So they can be used as the markers in sex identification of Asparagus officinalis.


This article traces the development of moral education in America,holding that the ethics of Protestants is the foundation of American moral education,and republican education,democratic education and civic education not only shape the American nationality,but also make the American society stronger. The traditions of American moral education are the historical causes of American's prosperity,but they are facing a lot of challenges in the present age.


Experimental results of a three-stage highly loaded fan drive turbine test program are presented. A plain blade turbine, a tandem blade turbine, and a tangentially leaned stator turbine were designed for the same velocity diagram and flowpath. Seven combinations of bladerows were tested to evaluate stage performances and effects of the tandem blading and leaned stator. The plain blade turbine design point total-to-total efficiency was 0.886. The turbine with the stage three leaned stator had the same efficiency with an improved exit swirl profile and increased hub reaction. Two-stage group tests showed that the two-stage turbine with tandem stage two stator had an efficiency of 0.880 compared to 0.868 for the plain blade two-stage turbine.


Measurements of the RMS magnitude, spectra and cross-correlations for the fluctuations in the beam, discharge and neutralizer keeper currents are presented for a 30-cm diameter dished grid ion thruster for a range of magnetic baffle currents and up to 2.0 amperes beam current. The ratio of RMS to mean ion beam current varied from 0.04 to 0.23. The spectra of the amplitudes of the beam and discharge current fluctuations were taken up to 9 MHz and show that the predominant amplitudes occur at frequencies of 10 kHz or below. The fall- off with increasing frequency is rapid. Frequen- cies above 100 kHz the spectral levels are 45 kb or more below the ma-yimiim peak amplitudes. The cross-correlations revealed the ion beam fluctuations to have large radial and axial scales which implied that the beam fluctuates as a whole or "in-phase". The cross-correlations of the beam and neutralizer keeper current fluctuations indicated the neutra- lizer contributions to the beam fluctuations to be small, but not negligible. The mode of operation of the thruster (values of beam and magnetic baffle currents) was significant in determining the RMS' magnitude and spectral shape of the beam fluctuations. The major oscillations were not found to be directly dependent on the power conditioner inverter frequencies.


The inhibition of thymus-derived lymphocyte-mediated cytolysis by histamine has been studied in a cytolytic system with immune C57BL/6 effector cells and DBA/2 mastocytoma target cells. Histamine inhibited cytolysis in a reversible manner, and stimulated intracellular cyclic AMP levels in the effector cell. Histamine inhibition was specifically antagonized by burimamide but not by other antihistamines, such as diphenhydramine. The specificity of this antagonism suggests that the histamine receptor on effector thymus-derived cells is of the histamine 2 type only.


LME (Lamines Marchands Europeens), part of the Beltrame Group, has an Electric Arc Furnace (EAF) and two rolling mills at Trith St-Leger, near Valenciennes in the Northern part of France and two other rolling mills located at Le Ruau (Belgium) and Schifflange(Luxembourg). The EAF plant at Trith St Leger produced 680,000 tons of billets in 2003. Air Liquide offers PYREJET™, a technology for EAF steelmaking already in operation on more than 35 furnaces worldwide. This sidewall-mounted oxygen and carbon injection system offers three steelmaking functions within one single tool. ALARC PC™ is another technology for EAF, which offers a dedicated low speed oxygen injection for an optimized post combustion. Both complementary technologies have been fully implemented and coupled on the 100 ton DC EAF at LME Trith St-Leger to increase productivity and to reduce electrical energy consumption. Industrial results with a complete PYREJET™ and ALARC PC™ system in operation indicate remarkable improvements through enhanced oxygen efficiency : • 37 kWh/ton electrical savings (from 412 kWh/ton to 375 kWh/ton) • 6 min. decrease in tap to tap time (from 60 min. to 54 min. of Tap to Tap Time) The implementation and the industrial operation of the multi-function PYREJET™ are presented in this paper. Special attention will be paid to the coupling with the ALARC PC™ system during melting and refining periods.


We present a novel software architecture for graphical interfaces to interactive theorem provers. It provides click'n prove functionality at the interface level without requiring support from the underlying theorem prover and enables users to extend that functionality through light-weight plugins. Building on established architectural and design patterns for interactive and extensible systems, the architecture also clarifies the relationship between the special application of theorem proving and conventional designs.


The analysis of financial crisis contagion mechanism is one of the most important issues in international financial research.Since 1990s the correlation between capital account openness and financial crisis contagion has attracted extensive academic concern.Based on the summary of existing literatures,the paper analyzes the financial crisis contagion mechanism.The results show that there exists a positive correlation between the capital account openness and financial crisis contagion.We need to strengthen the supervision of the short-term speculative capital flows,push forward the capital account openness cautiously and steadily,and take various measures to prevent and weaken the international financial crisis contagion effect.


This research continues to examine appropriate learning activities and environments to support student development and workforce readiness. In the current study college graduates were interviewed to gain the graduates' perspective of what transitional activities were needed to support readiness for the workforce. In the current study college graduates were interviewed to gain the graduates' perspective of what transitional activities were needed to support readiness for the workforce. The findings and recommendations include appropriate coaching, as well as implementation of specific strategies to support student readiness for the workforce by designing a plan for collaboration with companies to bridge student transition into the workforce.


Abstract Humans can use language to refer to and describe endless varieties of situations, thoughts, ideas, and topics, actual or hypothetical. This capacity, which distinguishes human language from communication systems of other animals, is referred to here as topic-open-endedness. A key factor in explaining topic-open-endedness early in the life of a new sign language is the nature of the linguistic symbols, the words, and the human ability to extend their meanings – e.g., through metonymy and metaphor – to novel semantic domains, applying a finite lexicon to infinite situations and topics. Other early language properties such as predication and negation facilitate creativity and flexibility from the beginning. The property of recursion accounts for the creation of an infinite number of sentences from a finite set of words and rules. But it cannot account for the open-endedness of the contents of those sentences. Therefore, the importance attributed to recursion as the sole mechanism that is uniquely human is overrated.


An increase in oil palm plantation area of ± 9.3 million hectares within 20 years (1997 – 2006) raises concerns of the international communities on the loss of diversity, including butterflies. Butterflies have multiple ecological functions, including as pollinator and ecosystem balancer, hence research about the impact of oil palm plantation development on the loss, gain, and diversity is important to conduct. The research was conducted in March 2018 in PKWE Plantation, West Kalimantan Province, by using Pollard transect method and trap in seven land covers. The land covers consist of two original land covers before made into oil palm plantation, in the form of shrubs and secondary forest, and five land covers after made into oil palm plantation, in the form of old, medium, young oil palm plantation, High Conservation Value (NKT) area, and yard. The total butterfly species found amounted to 49 species, 315 individuals, four families: Papilionidae (8 species), Pieridae (8 species), Nymphalidae (31 species), and Lycanidae (2 species). The highest number of species and diversity were discovered in the High Conservation Value (HCV) area (S=26; Dmg=6.24), while the lowest ones were located in a yard area (S=11; Dmg=2.09). Based on conservation status, there were a butterfly species which is protected namely Troides helena. Regarding the loss and gain of butterfly species, oil palm plantation development had caused a much lower loss than gain. With the loss of five species and gain of 27 species compared to the original land cover in the form of secondary forest, and the loss of three species and gain of 26 species compared to the original land cover in the form of shrubs.


Extensive field co]lections and the study of herbarium specimens have resulted in the addition of several species ofAlyrioplyllum L. to the flora ofChina (Li & Hsieh 1996, YiJ et al. 2001, Wang et al. 2002). RecentlM while conducting fieldwork in the Chang Jiang River basin, we fbund another overlooked species of AlyriophyUum in China that proved to be Ml ogunaense Miki, as shown by its glaucous emergent


The surveys show an increase in bicycle helmet wearing throughout Victoria during the period 1983 to 1987. In the metropolitan area the wearing rates in March 1987 were 67.9% for primary school children, 42.4% for suburban commuters and 19.5% for secondary school children. Helmet wearing rates in all categories were lower in 8 out of 10 country towns surveyed. The effect of the media campaign which targetted secondary school pupils before the 1987 survey was more evident in country towns. This succeeded in raising the helmet use by secondary school pupils in country areas almost level with that of secondary school pupils in Melbourne. The smaller proportion of people wearing helmets while cycling for fun or for short local trips indicates a need to emphasize the use of helmets for all bicycle use, not just for cycling to a defined destination such as school or work.


A R T I C L E I N F O A B S T R A C T Article history: Received: 29 June, 2020 Accepted: 21 August, 2020 Online: 09 September, 2020 Optimal integration of distributed generation (DG) into the distribution system results in reduced power losses and improved bus voltages. In this article, a combination of two techniques has been analyzed: The integration of DG and reconfiguration of the distribution system by removing the Normally Open Point NOP in different places of the system. These two techniques are applied to a real distribution network " distribution network of Kenitra city in Morroco", considering as key objectives the reduction of power loss and improvement of voltage profile. To investigate the effectiveness and robustness of our system a model was performed using ETAP. The simulation results improve that we can minimize greatly the power losses in the distribution network by the implementation of DGs and reconfiguring our distribution network.


In order to find an algorithm with the highest efficiency for solving the unit combination problem, the characteristics of the unit combination problem are discussed in this paper. The advantages and disadvantages of the current mainstream methods for solving the unit combination problem are comprehensively analyzed, and it is concluded that the current methods for solving the unit combination problem are difficult to balance computational efficiency and computational accuracy. The Lagrangian relaxation method absorbs the constraints into the objective function by introducing Lagrangian multipliers to reduce the difficult constraints in the unit combination problem, which reduces the size of the unit combination problem and overcomes the problem of "dimensional disaster". The computational analysis of different number of unit combinations and the analysis of the pairwise gap also confirm that the Lagrangian relaxation method can better deal with the unit combination problem.


How to cite this paper: Phaswana, I., & Pelser, T. (2021). A corporate governance and business ethics framework: The case study of bank subsidiaries in an emerging country. Journal of Governance & Regulation,


Objective:To explore the need and dissemination of scientific knowledge of Chinese medicine and their influence to college students by an investigation among the non-medical students in Guangdong Province.Method:The investigation was implemented with a questionnaire among the non-medical students in Guangdong Province.otally 147 responses were collected.Result:82.31% college students will choose Chinese medicine when they go to the clinic of hospitals.More than 75% consider the need to publicize the scientific knowledge of Chinese medicine,in which 21.77% thought the need is urgent.Web and family was the major approach to acquire scientific knowledge of Chinese medicine.The knowledge that most of the college students wanted to know was food therapy and health maintenance.The top three diseases which were considered in urgent need by most of students were stomach illness,cold and hepatitis.The primary objectives to learn the knowledge about Chinese medicine were longevity and disease prevention.The key points for disseminating knowledge of Chinese medicine was to express them in pictures with plain word descriptions.Conclusion:College students are one of the main populations for Chinese medical knowledge dissemination.Enhancing the propaganda on basic concepts of Chinese medicine has important practical significance.Internet and video media should be well applied in the dissemination of Chinese medicine knowledge.


Single-axis rotation strapdown inertial navigation system(SINS) is studied in this paper.A new rotation scheme is proposed to solve the problem that carrier motion has not been isolated which would cause incomplete error compensation leading to a considerable error.Based on the principle of rotation SINS,the traditional four-position rotation-stop method is revised to get the new rotation scheme.By using the proposed method,the errors caused by carrier motion are periodically compensated.In this way,the accuracy of the system can be greatly raised and the complexity of the system can also be reduced.Computer simulation has been taken for vehicles and vessels,and the result shows that the program can depress the constant drift errors caused by the carrier motion without isolating the carrier motion.


Effects of application of nitrogen as panicle-promoting fertilizer on grain yield and quality was studied with two mid-season rice cultivars,Huhan 15(indica)and Yangjing 4038(japonica)grown in pots as materials under three nitrogen fertilizer levels,low nitrogen level(LN,0.5g urea per pot),medium nitrogen level(MN,1.0g urea per pot),and high nitrogen level(HN,2.0g urea per pot)at the panicle initiation stage under high temperature.Both high temperature(mean temperature during the day/night at 35.1℃/20.8℃)and normal temperature(mean temperature during the day/night at 29.0℃/20.8℃)treatments were conducted during heading and grain filling.The grain yield and rice quality were investigated under these treatments.The results showed that at the same temperature,especially under high temperature,compared with the LN,the MN and HN significantly increased spikelet number per panicle,seed-setting rate,1000-grain weight,grain yield,head rice rate and short chain percentage in debranched amylopectin,and reduced chalky grains and long chain in debranched amylopectin,especially at MN.Application of paniclepromoting fertilizer also increased the photosynthetic rate of flag leaf,root oxidation activity,and activities of the key enzymes involved in sucrose-to-starch metabolic pathway in grains in the two cultivars.These results indicate that proper application of nitrogen as panicle fertilizer could maintain a higher grain yield and better quality of rice when subjected to high temperature during heading and grain filling,and increases in root and shoot activities contribute to the reducing adverse effects of high temperature on rice yield and quality.


Abstract The depiction of firearms in mass media coverage of active/mass shootings begets an important question: How do the security and law enforcement experts in charge of prevention, mitigation, and response think about firearms? To answer this question, a qualitative content analysis of firearms depictions in post 2010, North American based active/mass shooter instructional training videos was conducted. A sample of 24 videos was selected for analysis based on the previous criteria. The study utilized limited quantitative measures to produce an overall picture regarding numerous firearms characteristics as they related to depiction. Characteristics were coded into thematic categories and an overarching analytical theme. Overall, this study found evidence that depictions generally constituted of firearms characteristics which produced feelings of fear in the intended audience. A limited application of Protection Motivation Theory (PMT) was provided as a preliminary explanation for both the nature of the findings and the rationale behind such depictions. Implications for future research and the role of expert protection professional involved in the production of instructional media are discussed.


This project will present the design, construction, development, control and evaluation of an automatic function of electric fan. Fan is the important thing for circulation of air. The development of Automatic Mini Fan with Human Detector System by Using PIR Sensor presented in this project is required to fulfill the requirement of technologies today and it had been fabricate with new design. The automatic mini fan with two types of power supply which is Alternating Current (AC) and Direct Current (DC) can continuously function if one of the power supplies cannot be used. The human detection systems by using PIR sensor are implemented in this project and the detection range is up to 13 feet. The temperature sensors which maximum 70°C that are used in this project can automatically control the speed of fan up to 225 rpm. This automatic mini fan with human detection system contains combination of sensor, controller, motor and two types of power supply that controlled by Arduino UNO as the main controller. This project also presents the expected performance of the automatic mini fan with human detector system which the fan can rotate 0° to 180° and the construction of hardware and software development to gather the performance data. Finally, this project can give many benefits to people because it is portable and can save electricity. The result of this project becomes useful in the future.


Background. In cystic fibrosis-related diabetes (CFRD) screening, oral glucose tolerance test (OGTT) thresholds for detecting prediabetes and diabetes are defined by the 2-hour glucose (2 hG). Intermediate OGTT glucoses, between 0 and 2 hours, that are ≥200 mg/dL are deemed "indeterminate," although lower 1-hour glucose (1 hG) thresholds identify those at increased risk of type 2 diabetes in other populations, and may also better predict clinical decline in CF. Studies of 1 hG thresholds <200 mg/dL in people with CF are limited. Methods. A single center, retrospective chart review was performed of patients with 1 hG available on OGTTs collected between 2010 and 2019. In patients with ≥2 OGTTs, Kaplan–Meier analysis estimated likelihood of progression to CFRD based on a high vs. low 1 hG. In patients with ≥1 OGTT, mixed-effects models tested whether baseline 1 hG and 2 hG predicted growth and lung function trajectories. Results. A total of 243 individuals with CF were identified with at least 1 OGTT including a 1 hG, and n = 177 had ≥2 OGTTs. Baseline age (mean ± SD) was 12.4 ± 2.6 years with 3.2 ± 1.4 years of follow-up. Twenty-eight developed CFRD. All who developed CFRD had a 1 hG ≥ 155 mg/dL prior to 2 hG > 140 mg/dL. The average 1 hG was 267 mg/dL when 2 hG ≥ 200 mg/dL. In a subset with baseline 2 hG < 140 mg/dL, 1 hG ≥ 140 mg/dL conferred an increased 5 years risk of CFRD (

 p
 =
 0.036

 ). Baseline 2 hG predicted decline in FEV1%predicted, but 1 hG did not. Conclusions. In youth with CF, 1 hG ≥ 140 mg/dl is an early indicator of CFRD risk. However, 2 hG, rather than 1 hG, predicted lung function decline.


It is crucial for online service providers like Netflix to offer their viewers a selection of top-notch movies. In a bipartite network, this kind of challenge can be thought of as a ranking problem. This is a well-known issue that a ranking system can resolve. However, many traditional rating systems have the same flaw they favor older films over recent ones, despite of Basic services the fact that some recent films might have better quality. In the study, we propose a ranking method applying Equality rebalance methodology to minimize the time bias of the ranking in bipartite graphs Environment. Then, using three actual datasets as our ground truth benchmark, we run experiments. The research findings demonstrate that our proposed methodology enhances predictive performance or accuracy by at least 20% and as much as 80% while also lowering the time bias of ranking scores. The contribution of this paper shows the different types of algorithms for recommend the genre type with less computational time.


This paper presents predictive rotor current control of a variable speed wind energy conversion system. The conversion chain uses a doubly fed induction generator (DFIG) model employing finite control set model predictive control (FCS-MFC) for the controlling purpose of rotor side converter (RSC). The standard formulation selects the optimal switching state of the converter minimizing the error between predicted orthogonal rotor current components and their reference values which is then applied to the RSC of DFIG. The modified formulation enables RSC of DFIG to track the reference current with additional features of reduced switching frequency and voltage tracking ensuring better performance.


This document contains the formatting information for the papers presented at the International conference on
"Engineering Technology International Conference". The conference held at (Bali, Indonesia) during August 10-11, 2015. The microstructure and mechanical properties of the material to be welded mainly depends on the temperature during welding. The difficulty in measuring these temperatures during friction stir welding, pose a serious concern to researchers, practicing engineers and technicians. Hence, there is a necessity for searching alternate solutions. In the present research, a simulation model has been developed by using hyper works software to estimate the temperatures and flow stress. The modeling of Friction Stir Welded AA6061 alloy has been carried out by three dimensional nonlinear FEA model, the temperatures are evaluated. During the welding process the peak temperatures and flow stresses are presented around the rotating tool pin, and plates are found to be 615 0 C and 450 0 C.


To determine the role of glucagon in idiopathic leucine-sensitive hypoglycemia (LSH) and the effects of oral diazoxide (D), responses to oral L-leucine (L) were studied in 3 LSH children and in 6 controls. In controls mean plasma insulin (IRI), glucose (G) and glucagon (IRG) values were unchanged after L, 150 mg/kg. In LSH children after L, 50 mg/kg, mean±SEM plasma IRI rose from 14±3 to 41±5 μU/ml, mean plasma G fell from 72±4 to 35±3 mg/dl, mean plasma IRG increased 48±8%; each significantly different from beseline (P<0.025). Maximum changes in mean IRI, G and IRG values were at 15, 30 and 45 min.,respectively. In LSH children given L, while on D, 10 mg/kg/day, baseline values were similar, mean peak IRI was significantly lower and mean nadir G was significantly higher (P<0.05 and <0.025 respectively) compared to no D therapy; mean IRG rose less, but not significantly. One LSH child given L while on D, 20 mg/kg/day, showed minimal changes in IRI, G and IRG values. Following arginine infusions in another LSH child, ΔG values were 1 and 12 mg/dl, ΔIRI values were 56 and 21 μU/ml and ΔIRG values were 252 and 254 pg/ml, off and on D therapy, respectively. Peak changes were at 30 min.Conclusions: 1) In LSH children, given L orally, a rise in IRI precedes the fall in G and the rise in IRG. 2) D therapy blunts all of these changes in proportion to the D dose. 3) D does not directly inhibit IRG release. 4) The rise in IRG following L is secondary to the fall in G.


The invention provides a fixed type vehicle self-rescue device. The fixed type vehicle self-rescue device is mainly characterized in that a fixing anchor (1) is connected with a belt (2), and the belt (2) is connected with a wheel locking device (3). When a vehicle is trapped in a mud pit and a sand pit, the wheel locking device (3) is fixedly arranged on a wheel, then the fixing anchor (1) is put and fixed at one place along the vehicle driving direction, the vehicle moves forwards, the wheel rotates and winds the belt (2) onto a hub or the hub-shaped wheel locking device (3), and finally the vehicle can be driven out of the mud pit and the sand pit. The fixed type vehicle self-rescue device has the advantage that after the fixed type vehicle self-rescue device is arranged on the vehicle, when the vehicle is trapped in the mud pit and the sand pit, the self-rescue can be performed, and the consumption of too much labor is avoided.


Abstract : In 1966 N.V. Smirnov proposed the following combinatorial problem: given n objects of s+1 classes; how many ways can the n objects be arranged in a chain so that adjacent objects belong to separate classes. In 1967, O.V. Sarmanov and V.K. Zaharov derived some asympotic results on this problem. The present paper extends and generalizes this work.


Our daily life aspects are full of signs including icon, index, and symbol. The objectives of this research are to describe the way Google search engine logos lead to the identity of the event they represent and the meanings of
Google search engine logos . The data are the Google logos which are taken from the Google doodle official website . In collecting the data, the writer applied the documentation and observation. The theories used are the Pierce theory and Saussure theory. Pierce emphasized his theory on the representamen, interpretant and object. Then, Saussure emphasized his theory in analyzing sign
using the signifier and signified criteria. The type of the research is qualitative interpretative type. The several steps are done to analyze the data. In analyzing the way Google search engine logos lead to the identity of the event they represent , the steps are: analyzing the representamen , analyzing the interpretant , and analyzing the object. In analyzing meaning, the steps are:
analyzing signifier and analyzing the signified. This research shows that (1) the events that Google logos represent are : cultural, historical, personal, technological and literature symbol, and (2) the meanings are: referring to cultural, religion, science and entertainment that exist in society.


The paper deals with the problem of vocational teacher training content structuring in higher education establishments. The main attention is focused on the analysis of modern approaches to teaching content structuring and the possibilities of their application in vocational teacher training.


e15606Background: Cancer-associated fibroblasts (CAFs) reportedly regulate tumor progression by inducing tumor-stromal interaction; however, the roles of CAFs in hepatocellular carcinoma (HCC) deve...


The common plant diseases that have attacked field crops, vegetables, fruits, turf, and ornamental plants in Illinois in past years are likely to be present this year. The extent of disease development, however, depends on the combination of weather conditions during the growing season. Weather is a term used for the aerial environment. It includes light, temperature, snow, rain, humidity, dew, cloudiness, sunshine, wind, air currents, evaporation, and atmospheric pressure. Any one or some combination of these elements may affect disease occurrence. For example, in an apple orchard air movements that are either wind or eddy currents may lift scab fungus spores from old leaves on the ground up to succulent leaves and fruit on the trees.


The web of financial interests involving industry, advocacy, and academia in the management of osteoporosis described by Grey and Bolland is typical in many medical specialties.1 2 However, the ethical implications for each component of the web are different. Industry is a private enterprise, its goal is profit, and its managers are accountable to shareholders. Advocacy organisations are morally …


The present study deals with porous hematite nanostructures as antimicrobial drug delivery systems. Obtained nanoparticles have been analyzed by Transmission Electron Microscopy (TEM) and X-Ray Diffraction analysis. Porous ellipsoidal particles with a size range of 50–200 nm, which consist of 2–10 nm fragments, were observed. Drug adsorption onto the hematite nanostructures surface has been examined using penicillin and vancomycin as a model systems. Obtained adsorption isotherms represent weak interaction between adsorbate and adsorbent. The maximum adsorption capacities of penicillin and vancomycin were 8 and 6 mg/g respectively. The results suggest that synthesized hematite nanostructures could be used as drug carriers into Fe-Fe2O3 implants.


Ancillary allocated and non supplemental assignments to processing method and apparatus described in a wireless communication system. Forward link assignment block (FLAB) is received from the shared signaling medium access control (SS MAC) protocol. Whether FLAB medium access control identifiers (MAC ID) is equal to the MAC ID of the access terminal is determined, whether the auxiliary field FLAB equals "1" is determined.


Purpose: The  aim  of  the  study  was  to  analyze  the  performance dimensions and performance analysis techniques applied in studies of Asian port performance

Theoretical framework: The lack of literature in the context of port performance dimensions in Asian was  the  theoretical  basis  of  the study. A related study on Asian port performance was analysed and listed in the study based on thematic approach.

Design/methodology/approach: The PRISMA Statement (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was used to guide this research, based on the databases of the two most prominent sources of articles which is Web of Science and Scopus.

Findings: This review identified four main categories surrounding the dimensions of port performance, those being operational dimensions, dimensions surrounding customers' perspectives, logistical dimensions, and organizational dimensions. Furthermore, the following three performance analysis approaches were identified as being preferred by researchers of the Asian region: efficiency, productivity, and competitiveness.

Research, Practical & Social implications: The current findings of this research have shown that most studies on Asian ports focus on their efficiency and competitiveness rather than their productivity. A productivity survey might give a better overview of port performance as it concerns the actual output of the ports.

Originality/value: The systematic literature review (SLR) approach were hardly found in study of port performance. At the same time, the PRISMA method were applied to synthesized previous studies on port performance in Asian is another niche of the study.


-- Now a day's the fir-tree joint is very much evident from the literature that not much work carried out on effect of cooling passage of fir-tree root joint of turbine disk. The method of attaching the blades to the turbine disk is of considerable important, since the stress in the disk around the fixing or in the blade root has an important bearing on the limiting rim speed. On earlier days, whittle engine were attached by the dovetail fixing but this design was soon superseded by the fir -tree fixing that is now used in majority of gas turbine engines. The fir-tree fixing type involves very accurate machining to ensure that the loading is shared by all the serrations. When the turbine is stationary, then the blade is free in the serrations and is stiffened in the root by centrifugal loading when the turbine is rotating. This paper proposed the work on the development of geometric model of disc and blades for turbine.


Web services,which generally utilize XML-based SOAP as a data exchange protocol,can hardly achieve the same high performance as other distributed computing technologies.In this paper,we present a SOAP message optimization method based on Context-Store.In order to help minimize such overheads,we separate data content from the SOAP message syntax.The redundant or static message parts are stored in a shared metadata space—the Context-Store,so it may avoid transferring the redundant part of message in network and improve the web services performance.The empirical results show that our method outperforms conventional SOAP message process method and SOAP message compression method.


Abstract The basic corrosion rate at San Diego has been determined by exposure of an extensive series of mild steel panels for 6, 12, and 18 months. The corrosion rate as determined by weight loss, and the degree of pitting determined by pit depth measurements was measured for unprotected panels, and for three different levels of cathodic protection. The basic corrosion rate for unprotected panels over the one-year exposure was 25.8 mdd and the greatest pit depth found exceeded 60 thousandths of an inch. The fully protected panels suffered virtually no corrosion while the partially protected panels had a corrosion rate of 8.3 mdd. However, the greatest pit depth found on the partially protected panels was only 9 mils. 6.2.3, 2.2.2, 3.2.2, 5.2.1


This study deals with electrochemical preparation of cobalt oxide modified glassy carbon electrodes decorated with gold nanoparticles as an effective platform for dopamine (DA) detection. The experimental parameters affecting the oxidation signal of DA by square wave voltammetry have been evaluated. Under optimal conditions, developed sensor exhibited a linear response towards to DA in the concentration range of 6.0 10−8 to 7.5 10−6 M. The detection and quantification limits were calculated as 2.0 10−8 and 6.0 10−8M, respectively. The repeatability and reproducibility of the electrode were calculated as 13.2 and 16.1 % for 6.5 10-7 M (N = 3), respectively. Finally, the sensor was successfully applied for the DA analysis in artificial cerebrospinal fluid, and the mean recovery was found as 105.8 ±6.5 % by standard addition method.


The dynamic response of the dam-structure interaction system under the action of earthquake and wind was analyzed based on VOF method.Under the three working conditions of empty reservoir,dam-reservoir interaction,and dam-water-wind interaction,the dynamic displacement,absolute acceleration,and hydrodynamic response of the dam under the earthquake and wind load were calculated and analyzed.Meanwhile,the tracking of free surface based on VOF method verified its reliability and superiority.The results indicated that the interaction between the reservoir and dam is remarkably nonlinear.The dynamic displacement and absolute acceleration can be increased by the dam-water interaction.Furthermore,wind had no impacts on the dynamic displacement and absolute acceleration of the dam,but significant impacts on hydrodynamic pressure.


A cal. 20-year-resolution pollen record from Gonghai Lake presented the detailed process of mountain vegetation succession and East Asian Summer Monsoon (EASM) changes since the last deglaciation in Shanxi Province, North China. Modern vegetation distribution and lake surface pollen assemblages suggested that the fossil pollen mainly came from local and surrounding vegetation in Gonghai Lake, which reflected the elevational changes of plant communities in study area. From 14,700 to 11,100 cal. yr BP, open forests and mountain meadows dominated by shrubs and herbaceous species in surrounding area, suggesting a weak EASM with less precipitation. In the period between 11,100 and 7300 cal. yr BP, bushwoods and grasses were gradually replaced by mixed broadleaf-conifer forest, first developed by pioneer species of Betula and Populus and then replaced by Picea, Pinus, and Quercus, implying an enhanced EASM and increased temperature and precipitation. During the period of 7300–5000 cal. yr BP, warm-fitted trees became expanded and widespread, indicating a climax community of mixed broadleaf-conifer forest and warm and humid climate with higher temperature and sufficient precipitation and the strongest period of EASM. From 5000 to 1600 cal. yr BP, Pinus pollen increased, but Quercus pollen decreased, showing the breakup of the climax community and the recession of the EASM. Since 1600 cal. yr BP, under the threats of land reclamation and deforestation, forest cover sharply decreased, and mountain grass lands were developed. The EASM changes inferred from pollen record of Gonghai Lake were asynchronous to the oxygen isotope records of stalagmites from southern China. We suggest that the existence of remnant Northern Hemisphere ice sheets and relative low sea levels might hampered the northward penetration of the EASM in early Holocene, which caused the maximum monsoon precipitation to reach northern China until mid-Holocene.


At New York's plush Waldorf-Astoria hotel in March 1949, the internationally famous Soviet composer, Dimitri Shostakovich, experienced "the worst moment in [his] life." The lowest point was when as...


North Yorkshire County Council is to replace 240 street lights in Harrogate, many of them cast iron columns that have reached the end of their lives. ...


Point-of-Interest is an interesting research topic of personalized recommendation. In this paper, a new position-based recommendation framework is proposing by using the time attribute. We establish a user matrix with user check-in data sets that contain time and location information. The user matrix is divided into the sub-matrices according to the set period and then every sub-matrix is decomposed into the user checking preference matrix and position feature matrix by using the non-negative matrix factorization. The user's attendance preferences at each time are integrated to get the user's final check-in preference for the candidate location to make recommendations more consistent with the needs of users.


� Manfreda bulbulifera, a new species from Mexcalcingo, municipio Colotlipa, Guerrero, Mexico, is described and illustrated. The new species belongs to the group of Manfreda guttata, which is characterized by the presence of a reduced perianth tube, linear to lanceolate leaves and small-sized plants. Manfreda bulbulifera shows similarities with M. guttata (Jacobi et Bouche) Rose, M. littoralis Garcia-Mend., A. Castaneda et S. Franco and M. rubescens Rose. The new species differs from the others by its compressed corms, bulblets at the distal portion of the corm, very small perianthal tube, filiform segments, stamens and style longer than the tube and obclavate ovary.


Today's Internet Protocol Television (IPTV) is being offered and taking off, driving radical changes in the way telecom networks are designed. Future consumers will look for unique, personalized services through multiple devices, including the television. On demand content, Interactive TV, Video and voice communications, photo, music, and home video sharing, and online gaming, all delivered seamlessly, are a few examples of the services that consumers could receive. This requires innovative changes in the entire end-to- end service delivery architect, quality of service and customer management, reliability and security.


Objective: Bushen Zhuanggu Granula is a medicinal preparation made in Guangzhou General Hospital,with Herb Epimedii as the main ingredient.The aim of this study is to establish a method for measuring the content of Icariin in Bushen Zhuanggu Granula by high performance liquid chromatography(HPLC).Methods: Three batches of Bushen Zhuanggu Granula were measured for the content of Icariin by HPLC with an Agilent HC-18(150 mm × 4.6 mm,5 μm) column at the column temperature of 30 ℃,acetonitrile-water(30:70) as the mobile phase and the detection wavelength at 270 nm.Results: Icariin could be isolated from the other components,and showed a good linear relationship with the peak area at the range of 0.096 2-0.673 4 μg,r2=1(P0.001).The average recovery of Icariin was 94.4%(RSD = 1.83%,n=6).Conclusion: This method is sensitive,accurate,reproducible,specific and efficient for the measurement of the content of Bushen Zhuanggu Granula.


The Wiley Handbook of Christianity and Education provides a resource for students and scholars interested in the most important issues, trends, and developments in the relationship between Christianity and education. It offers a historical understanding of these two intertwined subjects with a view to creating a context for the myriad issues that characterize—and challenge—the relationship between Christianity and education today.


The Milagro Gamma Ray Observatory is the world's first large-area water Cherenkov detector capable of continuously monitoring the sky at TeV energies. Located in the mountains of northern New Mexico, Milagro will perform an all sky survey of the Northern Hemisphere at energies between 250 GeV and 50 TeV. With a high duty-cycle ( 100%), large detector area ( 5000m), and wide field-of-view ( 1 sr), Milagro is uniquely capable of searching for transient and DC sources of high-energy -ray emission. Milagro has been operating since February, 1999. The current status of the Milagro Observatory and initial results will be discussed.


The concept of high power microwave (HPM) short-duration pulse radar may have possibilities with the rapid development of HPM techniques. Short-duration pulse HPM radar has the advantages of high ECCM ability long range detection ability, high range resolution and high ability to detect targets in heavy scatter backgrounds. The DSP method is relatively simple. In this paper, the function, structure and constitution of a short-duration pulse radar experimental system which has been developed is presented. A method for creating, transmitting and receiving the short-duration pulse microwave signal is explored. A high range-resolution detection experiment for an air target and ground target is also preliminarily studied.


Chaos in the human brain and artificial neural networks is explained with a view to an understanding of human brain functions. Different chaotic solutions are known in neural network modelling, but the comparison of their quantitative characteristics with the human or animal EEGs can not be performed. In this work a model of the start and spread of epilepsy, based on neural nets, is presented. It is shown that the epilepsy-like phenomena can occur in the neural networks with increasing neuronal excitability. The dynamics of the quantitative EEG characteristics (correlation dimension, amplitude, largest Lyapunov exponent) is similar to one at the onset of epilepsy.


Performance-reporting standards have bankers caught between overhauling systems or losing trust business Performance-reporting standards developed by the asset management community are fast becoming a thorn in the side of trust bankers. In principle, there's nothing wrong with the standards, which were first developed in 1987 by the Financial Analysts Federation, one of the two groups that merged to form the Association for Investment Management and Research (AIMR). The other group was the Institute of Chartered Financial Analysts. In fact, it makes sense to adopt the AIMR standards voluntarily, provided your bank deals only with institutional trust clients. The heart of the problem for bankers is the breadth of the standards, whereby unless a trust institution can claim both personal and corporate trust compliance, real compliance doesn't exist. "They're two separate businesses," says Pamela Conroy, vice-president at Northern Trust Co., Chicago. "I shouldn't have to comply on the personal side to be able to state compliance on the institutional side. "The dilemma for a bank is that it has to comply firmwide in order to say it complies with the AIMR standards," she says. "We have to comply on all 20,000 [institutional and personal trust] portfolios we manage, or we can't say we comply at all." The difficulty banks have with accepting the AIMR standards is adopting accrual accounting for personal trust accounts. "Either allow us to do cash-based accrual accounting on the personal side--and we can disclose that--or allow us to split the compliance to comply on the institutional side and not on the personal," says Conroy. "In the meantime, we're accruing income on the personal trust accounts solely for the purpose of the performance calculations." The standards are something like bad-tasting medicine. Choosing to do without them means losing important trust clients, but agreeing to comply with them means changing complex performance-reporting procedures. What the standards ensure Put simply, conforming to the standards ensures that investment performance information presented to a client is consistent among portfolio managers and asset management firms. A client with assets managed by multiple firms, therefore, has a clearer picture of the true value of his holdings. Prior to implementation of the standards, money management firms could report investment performance using whichever method best reflected portfolio growth--as of a certain date, for example. Also, investment performance of only the best performing accounts could be presented, which didn't tell the whole story. Stating performance using the AIMR standards eliminates the temptation to manipulate performance measurement, and it reduces the risk of litigation stemming from such tactics. Since most nonbank money managers are members of AIMR, based in Charlottesville, Va., banks that choose to adopt the standards compete more effectively for asset management business. And winning that business solidifies personal and corporate banking relationships originally formed for depository or lending purposes. But bank trust departments shopping for new asset-management software are having to limit their options to those systems offering the ability to report performance according to the AIMR standards. For their part, software vendors that can't offer their customers the ability to comply with the AIMR standards will have an increasingly difficult time marketing their product to bank asset managers. Those institutions with proprietary portfolio management systems developed in-house for institutional accounts are having to change their systems or risk being in noncompliance with reporting standards fast becoming de facto. "It's a systems issue," says Conroy at Northern Trust, but at many larger banks, the systems are internally written, so there isn't a vendor to help solve the problem. …


This paper mainly focuses on the Ibsen's plays staged on the Albanian Theatre through the years. It mainly picks out the most famous plays of Ibsen, such as "An Enemy to the People", "A Doll's House" and "John Gabriel Borkman". The Albanian audience through the translation of Noli knows Henrik Ibsen, so the stage directors made their exquisite choices while deciding to put his plays on Albanian National Theatre, but not only. The cast of the actors managed to transmit Ibsen's most notorious ideas of modern drama, his drama of ideas also called discussion dramas. A special feature of Ibsen's dramas was not the events, but the characters. Each character is personalized, clearly drawn within some unexplored psychic targets; it is a strong "solitary", hardly manipulated, almost a pre-destined one, acting, and fitting itself to a hereditary condition, suddenly found in the panic of an increasing pressure that tends to cover or to bypass a terrifying secret. Its soul formula is irreparable. This was the motto of the actors while staging Ibsen's plays under the directions of the talented directors. DOI: 10.5901/jesr.2014.v4n6p535


In autonomous driving, localization is very important to ensure the accuracy of all the other tasks, and multi- vehicle cooperative localization is a popular research direction in recent years for its improvement on state estimation. However, due to the complex environment, complete information about relative pose for cooperative localization could sometimes be hard to be obtained. Since the inter-vehicle distance is easily measured, the use of inter-vehicle distance for multi-vehicle cooperative localization has become a meaningful topic. In this paper, we propose a general decentralized framework for the inter-vehicle distance aided cooperative localization. In order to fuse the inter-vehicle distance with the state estimation of ego-vehicle, the split covariance intersection filter (Split CIF) is used as the data fusion method. Then, we verify the advantages of the proposed method through simulation-based experiments, demonstrate its applicable conditions and provide its practical application scenarios.


The paper introduces the NWnets, a physics-informed deep learning model for reconstructing nearshore wave fields and mapping bathymetry. The physics encoded into the deep neural networks are the wave energy balance equation and dispersion relation. Insights into the model capability are gained through application of the NWnets to a laboratory experiment of wave transformation over a circular shoal. If the bathymetry and discrete measurements of wave height are available, the NWnets model is capable of simulating nearshore wave transformation. Moreover, the extended NWnets can be used for depth inversion if the bathymetry is unknown. Two methods for simultaneously estimating water depths and surface waves are presented. If surface wave number and limited wave height measurements are available from remote sensing platforms, the first method employs wave numbers and scarce measurements of wave height as training data. The second method utilizes scarce wave height and limited water depth measurements as training points to reconstruct bathymetry and wave fields. The results show that both methods are capable of simultaneously mapping the bathymetry and waves when the locations of training points are appropriately distributed.


SIRT1, the most conserved mammalian NAD+‐dependent protein deacetylase, is an important metabolic regulator. However, the mechanisms by which SIRT1 is regulated in vivo remain unclear. Here, we report that phosphorylation modification of T522 on SIRT1 is crucial for tissue‐specific regulation of SIRT1 activity in mice. Dephosphorylation of T522 is critical for repression of its activity during adipogenesis. The phospho‐T522 level is reduced during adipogenesis. Knocking‐in a constitutive T522 phosphorylation mimic activates the β‐catenin/GATA3 pathway, repressing PPARγ signaling, impairing differentiation of white adipocytes, and ameliorating high‐fat diet‐induced dyslipidemia in mice. In contrast, phosphorylation of T522 is crucial for activation of hepatic SIRT1 in response to over‐nutrition. Hepatic SIRT1 is hyperphosphorylated at T522 upon high‐fat diet feeding. Knocking‐in a SIRT1 mutant defective in T522 phosphorylation disrupts hepatic fatty acid oxidation, resulting in hepatic steatosis after high‐fat diet feeding. In addition, the T522 dephosphorylation mimic impairs systemic energy metabolism. Our findings unveil an important link between environmental cues, SIRT1 phosphorylation, and energy homeostasis and demonstrate that the phosphorylation of T522 is a critical element in tissue‐specific regulation of SIRT1 activity in vivo.


This paper reports a coarsely discretized dielectric Huygens' metasurface that comprises of only three elements per grating period. The resulting metasurface, which we termed as tripartite dielectric Huygens' metasurface (TD-HMS), greatly simplifies the design leading to a cost-effective and robust metasurface for efficient electromagnetic wave manipulation. Through full-wave electromagnetic simulations at 60 GHz, we show that the proposed TDHMS can achieve efficient anomalous transmission, where the desired diffracted mode contains more than 80% of the total transmitted power.


Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic inflammatory conditions of the gastrointestinal tract characterized by a relapsing and remitting course. Aim - to analyze clinical data and the most significant hematological and biochemical blood parameters used for diagnosis in patients with ulcerative colitis. Materials and methods. Between 2020 and 2021 examined 50 patients with the diagnosis "Ulcerative colitis" living in the Samara region. The diagnosis of ulcerative colitis was confirmed by a combination of clinical, radiological, endoscopic, and histopathological criteria generally accepted for inflammatory bowel diseases. A hematological blood test was performed on an automatic hematological analyzer Sysmex KX-21N, Japan, and a biochemical blood test was performed on an automatic biochemical analyzer Hitachi 902, Japan. Results. In the biochemical analysis of blood, an increase in the content of C-reactive protein in the blood is expected in 64% of patients. In 40% of patients, the concentration of total protein and electrolytes decreases. An increase in glucose levels was revealed in 44% of patients, in 10% of cases, a decrease in creatinine concentration, an increase in the activity of ALAT and ASAT was noted in 6 and 4% of cases, respectively. Reduced urea levels are noted in 6% of patients. Conclusion. As a result of the study, the data necessary for the diagnosis and monitoring of the effectiveness of the treatment of ulcerative colitis were obtained.


Aim: This study's objective is to determine how polypropylene fibre impacts self-healing concrete's flexural strength. Materials and Methods: Investigation was divided into two groups, with each group preparing 18 samples with Gpower (80 percent). Group-1 denotes conventional self-healing bacterial concrete, while Group-2 denotes polypropylene fibre reinforced self-healing bacterial concrete. The number of samples was determined using clinical software and values taken from previous research publications. The independent sample T-test, performed using SPSS software version 21, demonstrates a substantial increase in the flexural strength of the fibre reinforced self-healing concrete. Result: In comparison to conventional self-healing bacterial concrete, polypropylene fibre reinforced self-healing bacterial concrete has a 19% higher flexural strength. The significance of the events was 0.354 (p>0.05), indicating that there was no significant statistical difference. The flexural strength of polypropylene reinforced bacterial concrete had a standard deviation of 0.79623. Conclusion: According to the findings of this experiment, M20 grade self-healing bacterial concrete reinforced with polypropylene fibre has a stronger flexural strength than regular self-healing bacterial concrete.


This paper assesses the ability of automobile insurance prices to distinguish the 2:1 ratio of men's to women's annual mileage, which is linked to a similar ratio of accident involvement per year. Review of current price classes by driver sex and age, by future mileage, and by past driver record reveals severe limitations to their capacity to assess women's lower mileage exposure to risk of accidents. Accidents are modeled as a process of random sampling of vehicle miles traveled (VMT) by cars in an insurance class. This analogy underscores 1) the impossibility of pricing by individual accident record and 2) the paramount importance of odometer-measured vehicle miles of on-the-road exposure for assessing individual accident risk in money terms. The need for risk classification as the essential complement to exposure measurement is shown by considering how a single insurance surcharge on gasoline ("pay at the pump" insurance) as an exposure measure would perversely affect incentives for risk control. Current risk classification is profoundly compromised because individual exposure is not measured. An efficient per-mile premium system combining exposure measurement and risk classification is described. Current flat premiums are compared to premiums that would increase in direct proportion to miles of driving exposure. This comparison shows how individuals, and also women and men as groups, would be affected by changing insurance from a fixed cost of car ownership to a per-mile operating cost of car use.


The field of education has been completely revolutionized due to the worldwide pandemic caused by COVID-19. Student evaluations, used as tools in the teaching-learning process, have had to be adapted to online learning environments (or in some cases hybrid online/in class learning) that most educational centers are currently using. This descriptive, quantitatively focused study evaluates the effectiveness of ExamView as a tool to construct and apply evaluation questionnaires in the online learning setting. During the study, 91 students belonging to three classes of Linear Algebra 1 participated in a survey evaluating the efficiency, pertinence, and motivation of three assessment models: Model A, a traditional, pen and paper questionnaire; Model B, an online multiple-choice questionnaire; and Model C, an online questionnaire including questions in a variety of formats such as multiple-choice, true/false, short answer, and matching. The results of the survey show that due to the familiarity and simplicity that students perceive when answering this type of multiple-choice questionnaire, more students prefer Model B than the other two models.


future. Both salts proved very active, and were constant in their effects; the hydriodate appeared to be somewhat more powerful than the hydrochlorate, which is perhaps due to its being crystalline, while the latter is amorphous. Their action closely resembles that of atropin; whether it is really different in kind, and in what degree it differs from that of atropin, however, has not yet been ascertained. It appears as if in certain morbid conditions, in which atropin has been used with variable or doubtful effect, hyoscin, and more especially its hydriodate, produced a more powerful and constant r V/WAiU VtVll f


The reason which produced corrupt to the school sports competition carries on from the sociological angle of view searched analyzes,the research obtained: The competition organization public decision-making and the policy-making performer private interest contradiction is the objective foundation;The anticipated income and the investigation,penalty dynamics are the final policy-making factors;The individual values,the moral outlook are the intrinsic factors;The society deviates from the norm;and the social role is the social cause.


A method is presented to compute the sound field of a hyperthermia transducer in continuous wave operation. The approach consists of modelling the transducer with point sources and summing their individual contributions where the field value is desired. This spherical wave decomposition method is not new, the novelty of the method resides in the programming technique used to avoid repeated computations by the use of a tree data structure. The increased speed obtained makes this method suitable for use on a personal computer. Timing comparisons are presented, as well as a comparison of computed fields with previously published results.


This study examines the potential application of an EMG technology as an assistive control method for individuals with severe physical disabilities. The usability and acceptability of a prototype EMG switch was evaluated with health care professionals, researchers and end users using participatory approaches.


The lack of public information on how to invest tobe a major cause of the lack of public interest on capitalmarket investment. Besides of that, for the certaininstrument such as mutual funds of society will getdifficulty in judging and choosing the mutual funds whichbe able to give optimal performance and benefit influencesthe slowness of mutual funds development.Result from this research activity is for finding themeasurement of the performance mutual funds stock byusing stage of stock rotation and stage of stock mutual fundwhich is made to be a accounting management informationsystem and financial. With this stock mutual fundperformance measurement model so that can be tool ofimportant information for investor, society about theinvestment will have good potency of financial and themajor elements causeof the performance of that mutualfunds in capital market. Therefore, society can value andchoose mutual fund which be able to give performance andoptimalization in benefit especially in capital market.Explanatory research, this research has the goal to explainthe relationship between the research variable through thehypotheses based on the data, such as: rotation stage andrisk stage concerning the stock of mutual fund performance.Multiple regression analysis will be used to test the effectof two or more independent variables on the dependentvariable . independent variable in this research is rotationstage and risk stage. Meanwhile in independent variable isthe stock mutual fund performance. The research result forthe simulation of measuring stock of mutual funds model,to measure the stock mutual funds performance. KEY WORDS: performance, mutual funds, stock risk.


Single image Super-resolution (SISR) is a computer vision (CV) problem that aims to acquire a high-resolution (HR) image from a distorted low-resolution (LR) image, making it a valuable technology that could be utilized in various fields such as photography, medical imaging, satellite imaging, etc. As a result of the advancement of computing hardware and richer computational power, deep learning-based image super-resolution models have emerged at an unprecedented rate. This paper reviews SISR and its recent development. Three widely used deep architectures: convolutional neural network (CNN), generative adversarial network (GAN), and transformer are explained. Next, six different deep learning-based models that summarize research on SISR are analyzed. Finally, this review concludes with applications of SR, current challenges SISR models encountered, and potential future research directions.


Essentials Venous thromboembolism (VTE) prevention strategies require effective risk assessment models. We sought to validate the Khorana Risk Score (KRS) in patients with lung cancer. A high KRS was not predictive of VTE but was independently associated with all‐cause mortality. Our findings stress the need for a lung cancer‐specific VTE risk assessment model.


The main objective of this study was to examine symptoms and underlying factors of depression among inmates of Bonga Town correctional center. The institution-based cross-sectional study design was employed and through systematic sampling, 327 inmates from February to March 2017 were considered for this study. Data was collected by using a standardized self-reported questionnaire. Stepwise regression was conducted to identify associated factors. Mann Whitney U test was used to determine gender difference on symptoms of depression. The finding of this study revealed symptoms of depression (change in appetite, change in sleep pattern, loss of energy, self-dislike) prevail among inmates of Bonga Town correctional center. The level of depression was moderate 52.29%. Pessimism (r=.120, P=.030), self-dislike (r=.136, P=.014) and crying (r=.142, p=.010) were symptoms of depression associated with inmates years of incarceration. Socio-demographic factors, environmental factors were to as well as psychosocial factors were associated with depression. There was a significant gender difference in each symptom of depression; i.e female inmates suffered more than male inmates in each symptom of. Bonga correctional center communities should work cooperatively with Bonga G/Tsadik Shawo hospital to help inmates who were at risk.


In this paper, a novel class of quaternion-valued memristive neural networks (QVMNNs) that considers both the spatial factor and Markov jump phenomenon is proposed, the finite/fixed-time anti-synchronization (F/FTAS) of which is investigated. It is worth mentioning that the considered master and slave systems are assumed to jump along two inconsistent Markov chains, which is a first attempt at the issue of the anti-synchronization of Markovian systems and may be more realistic than most existing Markovian systems' models. Then, a suitable feedback controller is designed, such that the error system can be finite/fixed-time stable. Moreover, by integrating algebraic inequality technologies and Lyapunov theory, a new F/FTAS theorem can be obtained for the proposed systems. Finally, this paper provides two examples, so that the rationality, superiority, and practical value of the main results can be illustrated.


The chief aim of this paper is to provide a short technical summary of the principal noise-model results (11-[11], developed by the author to date, and to consider their major implications for 1) measurement, and 2) performance prediction and evaluation. The discussion is illustrated by a concise review of model statistics, methods of estimating the model parameters, including the effects on accuracy of finite data samples. A variety of signal detection problems are similarly used to illustrate the very large potential improvement possible when optimum algorithms are employed, vis-a-vis most of the currently used systems, which are conventionally optimized for Gaussian interference. Conditions for realizing such gains are also given, and the principal key properties of these new, general models are discussed. These models make possible, for the first time, a systematic treatment of real-world EMI environments, both for measurement and assessment, and for receiver performance therein.


Accountancy existed since the ancient civilizations, when the man did not even know the conventional counting system, but with the need to follow the evolution of his flock, the counting system with scratches on trees or stones, as from that moment the accounting has become part of man's life and it has evolved throughout the historical process of humanity. Only in the early nineteenth century that accounting ceased to be a simple tool for providing information. In the rural area, we have today a more precisely and controlled accounting, not only to ascertain the heads of animals in the property, but a way to control the familiar rural heritage in general, directing property's inputs and outputs, managing all cash flows, because the farm is also a company, being the entrepreneur its own proprietary. Inside the culture ranching and farming, we have the crop production portion with the temporary or permanent culture. For the property success it is necessary to pay attention to the costs of expenses, that investment requires being both relevant, variable and fixed costs. The bean crop is a temporary cultivation


Tree species identification constitutes a bottleneck in remote sensing applications. Waveform LiDAR has been shown to offer potential over discrete-return observations, and we assessed if the combination of two-wavelength waveform data can lead to further improvements. A total of 2532 trees representing seven living and dead conifer and deciduous species classes found in Hyytiälä forests in southern Finland were included in the experiments. LiDAR data was acquired by two single-wavelength sensors. The 1064-nm and 1550-nm data were radiometrically corrected to enable range-normalization using the radar equation. Pulses were traced through the canopy, and by applying 3D crown models, the return waveforms were assigned to individual trees. Crown models and a terrain model enabled a further split of the waveforms to strata representing the crown, understory and ground segments. Different geometric and radiometric waveform attributes were extracted per return pulse and aggregated to tree-level mean and standard deviation features. We analyzed the effect of tree size on the features, the correlation between features and the between-species differences of the waveform features. Feature importance for species classification was derived using F-test and the Random Forest algorithm. Classification tests showed significant improvement in overall accuracy (74→83% with 7 classes, 88→91% with 4 classes) when the 1064-nm and 1550-nm features were merged. Most features were not invariant to tree size, and the dependencies differed between species and LiDAR wavelength. The differences were likely driven by factors such as bark reflectance, height growth induced structural changes near the treetop as well as foliage density in old trees.


. All-cellulose composites were prepared by dispersing kraft fibers in a matrix made from pulp dissolved in NaOH-water. To hydrophobize the composite surface while maintaining the material fully bio-based and biodegradable, layer-by-layer deposition of cationic starch and carnauba wax was performed. Various options of surface coating, drying, and curing were tested, including partial and complete melting of the wax. The composite surface was characterized by water contact angle, roughness and scanning electron microscopy, and material properties by adsorption and absorption of water (in vapor and liquid form) and tensile testing. The highest water contact angle was obtained when the layer-by-layer deposition was performed by dipping the dry composite into cationic starch solution, then in wax dispersion, and partially melting the wax after coating. However, it was demonstrated that the dipping approach was detrimental to material tensile properties, due to heterogeneous swelling of cellulose during the treatment and multiple drying sequences. Process optimization via spraying resulted in composites with Young's modulus of 6 GPa and hydrophobic surface with water contact angle 122°C.


【Objective】To investigate the rate of depression in the hypertensive patients and the therapeutic effct of paroxetine.【Methods】From January 2003 to June 2005,one thousand and eighty patients of hypentension complicated with depression were analysed and evaluated with Hamilton rating scale for depression(HAMD).Depression was treated with paroxetine for 4 weeks.【Results】There were 113 cases of depression in 1 080 hypertensive patients with a morbidity rate of 10.46%;76 cases(67.25%) of depression were female;among 62 cases of premature heart beat,16 cases(25.81%) with depression.The higher the grade of hypertension,the higher the depression morbidity rate.After treatment with paroxetine the HAMD decreased significantly(P0.01).【Conclusion】Great attention should be paid to hypertension with depression,expeciably to high grade of hypertension or with premature heart beat.Paroxetine is very effective to treat depression with hypertension.


Baseline correction is an key step in signal pretreatment. The result influences the processing of the next step directly, so it has important actual meaning to find out a method which is simply and available. In this article, we propose an baseline correction method which is based on least square method. Through a great deal of experiment, we prove that the method we propose is a kind of fast, available method, and has maneuverability.


Colorectal cancer, one of the most frequent cancers worldwide, is more prevalent in North America, Argentina, Australia, New Zealand, Western Europe, Japan and Israel and, for this reason, is commonly regarded as a Western lifestyle disease. The progressive introduction of Western dietary habits, especially increased fat intake and reduced carbohydrate and dietary fiber intake is associated with an increased incidence of colorectal cancer and related deaths. This is the reason of a marked interest in the understanding of cell and molecular mechanisms underlying the carcinogenetic processes. The advanced neoplasm, including colorectal cancer, contain a large number of genetic and molecular alterations that contribute to their neoplastic progression. It is well known that early detection of malignancies in different tissues is quite important for reducing the disease. Cancer that is of epithelial origin is caused by both external and internal factors. These causal factors may act together or in sequence to initiate and /or promote cancer. In spite of knowing more than ever about the genetic and cellular events that can accelerate or inhibit cancer induction, cancer is still the number one health concern in the world, especially in Western and Westernized countries.


in the annual time scale. The cyclone characteristics dataset have been obtained based on the updated Serreze (1997) algorithm to daily Sea Level Pressure (SLP) data with six-hour intervals, which have been widely used to monitor extratropical cyclones in previous studies. Statistical analysis demonstrates that it plays a crucial role of the extratropical cyclones entering the APS in July, August and September (JAS), which are mostly from the Eurasia. The summertime sea ice area in APS reduces (increases) significantly with the increasing (decreasing) extratropical cyclones in JAS. The negative correlation is especially significant in the Chukchi Sea, the Beaufort Sea, the East Siberian Sea and the Central Arctic Ocean. Based on the monthly ERA-interim reanalysis data from 1978 to 2016, including 2 m temperature, sea surface temperature, water vapor, surface level pressure, provided by European Centre for Medium-Range Weather Forecast (ECWMF), it is also revealed that the activity of extratropical cyclones can impact sea ice both thermodynamically and dynamically. Intensified extratropical cyclones would affect processes of surface energy balance and heat advection, leading to the increasing air temperature above the APS and contributing to the ice melting. Meanwhile, surface winds associated with the cyclone are likely to affect the sea ice motion and expand the area of open water, which result in ocean warming and ice melting, especially in the marginal ice zone. Moreover, in the East Siberian Sea, cyclonic winds tend to transport the ice eastwards and southwards to warmer areas, which also aggravate the further melting. In general, the melting of summertime sea ice in the APS is greatly affected by thermodynamic processes of extratropical cyclones, while dynamic processes have limited impact, particularly in the marginal ice zone. It should be noted that, as the Arctic continues to warm up, mounting evidences suggest that the Arctic sea ice has become continuously thinner, which means less energy is required to achieve a reduction in areal coverage. Therefore, abundant reasons indicate that the cyclone activity will play an increasingly important role in the Arctic sea ice variability and it will remain a heated topic of debate for the coming future.


This article designs a posture correction device based on the principle of infrared ranging. A set of distance and corresponding infrared signal data is obtained by the sampling method, and then the data is analyzed to obtain the function of the distance and the output voltage. The infrared module is used to measure the real-time distance from the human head to the desktop, and the distance is used as a reference to remind the sitting posture of the user. The buzzer will be triggered, and an alarm will be generated when the height of user's hand is beyond the set range during use. Unlike traditional mechanical and wearable devices, this device can achieve noncontact measurement, will not restrain human movement or make the body produce physical dependence.


Male homosexual preference (MHP) is present in many human societies. Because homosexual mate preferences are associated with lower fecundity, many evolutionary explanations have been advanced to account for the persistence of this trait, with varying degrees of success. After reviewing a number of these hypotheses and finding them lacking, we propose a new hypothesis that depends on the observed greater empathy and reduced hostility of men who express MHP. This gives them a central role in the performance of groups or teams of males and/or females where cooperation and intra-team coherence are at a premium. Teams that contain men with MHP will, we propose, outcompete teams without such men. The links we propose between personality traits and team performance do not require homosexual activity within the group. Our hypothesis is supported by observations of the personality traits associated with MHP, such as agreeableness, which we link to the literature on sports and other kinds of teams and groups. Our hypothesis could be examined through direct study of team performance, enabling the topic to move beyond evolutionary theorizing. We note too that although we set out to develop an additional account for the evolutionary maintenance of MHP, our hypothesis may also have relevance to better performance among the diverse teams whose efficient performance is so important in modern society.


The availability of newer antiviral agents, as well as comprehensive treatment recommendations, has equipped clinicians with sufficient options to formulate hepatitis B virus (HBV) treatment regimens and individualize therapeutic strategies. These advances are particularly pertinent to Asian/Pacific Islander patients, who comprise the majority of chronic HBV infections in the United States and respond somewhat differently to certain drugs. This article reviews the most recent guideline recommendations on goals, treatment indications, therapeutic duration and endpoints, and monitoring of HBV treatment. In advocating an individualized approach to HBV treatment, currently available agents are further introduced separately. Treatment strategies for special populations (ie, pregnancy, HIV coinfection, cirrhosis, and post-liver transplantation) are also discussed. (Adv Stud Med. 2007;7(15):482-490)


This article introduces the concept of personal empowerment as a form of transformative learning. It focuses on commonly ignored but enhancing elements of mathematics learning and argues that crucial personal resources can be essentially promoted by high engagement in mathematical problem solving, inquiry, and collaboration. This personal empowerment is considered in three forms: self-empowerment, cognitive empowerment, and social empowerment. We report results from semi-structured interviews with undergraduate students who participated in college mathematics classes that implemented inquiry-based learning at four research universities. The findings support the idea that learning mathematics in classroom situations that use student activity, deep engagement, and collaboration can be strongly transformative for individual students. Not only do these courses enhance students' thinking and problem-solving skills but they also significantly promote self-perceptions, agency and self-regulatory activity, and social skills. Positive elements of these classroom practices for students' personal empowerment and transformative learning are discussed.


Water treadmill is a modality in veterinary medical rehabilitation belongs to therapeutic exercise with natural muscle stimulation. Water treadmill use advantageous physical properties of water to improve joint flexibility, endurance, balance, and animal posture by increasing muscle mass and strength, range of motion, and reducing pain. Water treadmills are often used to rehabilitate hind limb musculoskeletal problems in dogs with hip dysplasia. Hip dysplasia can occur in all dog breeds including the Beagle. A five year old Beagle, female sex, weighing 14.60 kg came to the Mody Pet's Club and RnD Clinic with complaints of limping and weakness on his hind legs. The results of the physical examination showed the dog was lame with a score of 2/4. The results of the radiographic examination observed moderate degree of hip dysplasia. Measurement of the thigh muscles showed muscle atrophy. The therapy carried out was therapeutic exercise with a water treadmill every week for ten times. The results of the study concluded that water treadmill therapy provided an improvement in the condition of dogs with moderate hip dysplasia to close to mild hip dysplasia.