Introduction Systemic inflammation may affect the brain by aggravating the stage of encephalopathy and increasing intracranial pressure (ICP) especially if liver insufficiency with hyperammonemia is present. The aim of this study was to determine if the influence of concomitant hyperammonemia and lipopolysaccharide (LPS) on the brain can be prevented by dexamethasone and cyclooxygenase (COX) inhibitors. Method Fifty-four male Wistar rats, 6 in each group, were divided into the following groups: Saline+saline; LPS (2mg/kg)+saline; LPS+indomethacin (10mg/kg); LPS+diclofenac (10mg/kg); LPS+dexamethasone (2mg/kg) in experiment A. Experiment-B included the following groups: LPS+NH3 (140μmol/kg/min)+saline; LPS+NH3+indomethacin; LPS+NH3+diclofenac and LPS+NH3+dexamethasone. ICP was monitored via a catheter placed in cisterna magna and changes in CBF were recorded by laser Doppler flowmetry. Results LPS with and without NH3 induced a similar increase in plasma 6-keto-prostaglandin-F1α (6-keto-PGF1α) concentration together with a concomitant rise in CBF and ICP. Indomethacin and diclofenac prevented the increase in ICP by LPS alone, and with the addition of NH3 the increase in both CBF and ICP, which was associated with a decrease in 6-keto-PGF1α. Dexamethasone only reduced the LPS induced increase in ICP but not CBF, and partly the 6-keto-PGF1α plasma concentration in the combined setup. Conclusion These data indicate that activation of cycloooxygenases is of central importance for development of cerebral hyperemia and high ICP during concomitant systemic inflammation and hyperammonemia.


. In a general geometric setting, we prove different characterizations of a local version of Muckenhoupt A ∞ weights. As an application, we obtain conclusions about the relationship between this class and the one-weight boundedness of local singular integrals from L ∞ to BMO .


Existing hierarchically semi-separable construction algorithms for dense $n \times n$ matrices require as much as $O(n^2)$ peak workspace memory, at a cost of $O(n^2)$ flops. An algorithm is presented which requires $O(n^{1.5})$ peak worskpace memory in the worst case, while still requiring only $O(n^2)$ flops.


A scheme of a boundary-element method is given in combination with a convocation quadrature method. The modifications of the convocation quadrature method are considered. The results of numerical experiments showing the advantages of the obtained modifications are presented.


The invention mainly relates to the technique field of a processing method used before extracting the medical extracts of red clover, in particular to a preparation method for extracting medical red clover raw material of isoflavone. The invention is characterized by the following steps of: cleaning the obtained red clover, which is then kneaded into threadiness by a cutter, and then putting someclean water in; sending the thread-shaped red clover into a presser for extrusion; sending the red clover in which water is extruded out into a crusher for smashing into threads from the block shape;and sending the red clover threads into a dryer for parching. The procedures of pouring clean water for rinsing and extruding water out when the red clover is kneaded exclude nutrient indigents such as chlorophyll and protein and the like rich in the red clover to maximum extent, thereby reaching the purpose of little volume when extracting isoflavone from red clover, high purity and raising production efficiency.


Under the general framework of a previous paper, a unified approach via filtering is developed to estimate stochastic volatility for micromovement models. The key feature of the models is that they can be transformed as filtering problems with counting process observations. In order to obtain trade-by-trade, real-time Bayes estimates of stochastic volatility, the Markov chain approximation method is applied to the filtering equation to construct a consistent recursive algorithm, which computes the joint posterior. To illustrate the approach, a recursive algorithm is constructed in detail for a jumping stochastic volatility micromovement model. Simulation results show that the Bayes estimates for stochastic volatilities capture the movement of volatility. Trade-by-trade stochastic volatility estimates for a Microsoft transaction data set are obtained and they provide strong affirmative evidence that volatility changes even more dramatically at trade-by-trade level.


The article is devoted an actual problem of research of the professional competence of the student. In the article the comparative characteristic of substantial descriptions professional competence students-graduates of economic and legal specialities is given, the general and specific components of these competence are revealed and formalized, key directions of their formation and development are advanced. On the basis of the conducted analysis imperatives of educational activity and the recommendation about the organisation of educational activity of the student for formation of the professional competence are offered. The author comes to a conclusion that acquisition of two qualifications the economist and the lawyer increases competitiveness of the graduate of high school under condition of deep understanding of the contents of professional work in these areas.


This paper describes a method for estimating pedestrian traffic volume by using video cameras. In the Umeda underground mall in Osaka City, we estimated the traffic volume without tracking technology and while protecting pedestrian's privacy. We developed an original algorithm that roughly estimates the traffic volume of pedestrians from sequential images of video cameras. We focused on a line on each image cut out from video and made a new image which shows the spatiotemporal distribution of pedestrians. We defined this image as 'time historical image of pedestrian spots (THIPS)'. In a THIPS, a pedestrian is regarded as a cluster of connected pixels with the same label. We captured the spatiotemporal distribution of pedestrians by using these images. We found that this algorithm requires a THIPS to estimate the number of pedestrians who passed the spot for a few minutes and plural THIPSs to estimate their traveling directions. Finally, we concluded that this algorithm is an efficient means of estimating pedestrian traffic volume.


Purpose – The study reported here concerned production of green pigments, hydrated nickel(II) silicates and oxides, obtained by precipitation from solutions of sodium metasilicate and sodium hydroxide using nickel(II) sulphate.Design/methodology/approach – The pigments were analysed using a number of techniques including scanning electron microscopy for particle surface morphology and dynamic light scattering for particle structure and the tendency of the particles to agglomerate.Findings – The most desirable physicochemical parameters were shown by highly dispersed nickel(II) silicates precipitated in presence of the modifying agents. Silicate pigments precipitated in the presence of Rokanol K‐7 had low bulk densities, a high capacity to absorb water, dibutyl phthalate and paraffin oil within the primary particles, which is particularly noteworthy.Practical implications – Due to their good dispersibility, well developed surface and appropriate coating power, coloured silicates of, e.g. chromium(III) and ...


The paper focuses on modeling and experimental investigations of electromagnetic waves propagating along the surface of biological objects. Wave propagation parameters such as attenuation and phase velocity are of main interest. The results of numerical simulations are compared with experimental data.


Ever wonder what is planted in front of PHS? This subject guide will provide information on the plants currently planted in and around PHS.

PHS Project Manager Sam Keitch designs and plant these attractive displays. Additional resources to learn about plants and planting


Training samples need to be labeled before being used to train classification model, which usually takes too much labor and material resources. Recently, this problem has attracted widespread attention. In order to reduce the workload of labeling samples, we propose a novel active learning methodology, which uses locally linear reconstruction coefficients to construct semi-supervised data manifold adaptive kernel space. Comparing the new method with other sampling approaches on several real-world image datasets, experimental results indicate that the novel algorithm has preferable classification ability. Especially, it can show higher classification accuracy under the condition that only a few samples are selected to train the classifier model.


A3-YEAR-OLD GIRL NATIVE OF THE TRIBE NGOBE-BUGLE (PANAMA) WAS REferred for evaluation of a history of skin fragility and blister formation since adoption 2 years earlier. The child's adoptive parents were unaware of the patient's or her family's medical history. Lesions were mainly located in sites of trauma and rapidly evolved to form crusts, ultimately leaving some pigmentary changes. Skin examination revealed erosions and crusts over the face and fingers. There was dyspigmentation with hyperpigmented and hypopigmented macules on both sun-exposed and non–sun-exposed areas. The skin was atrophic, with cigarette-paper–like wrinkling, especially over the dorsa of the hands and feet (FIGURE 1). Mild proximal syndactyly was present between the middle and ring fingers (FIGURE 2). There were no milia (FIGURE 3). Nails, gingiva, and mucous membranes were normal. What Would You Do Next?


A method for the explicit computation of the Lyapunov exponents of certain Markov processes is developed. Its utility is demonstrated by an application to two-dimensional random evolution differential equations. Our approach exploits the relation between the Lyapunov exponent and the p-moment Lyapunov exponents, as was first observed and studied by Arnold [1]. The p-moment Lyapunov exponent is characterized by the domain in which the Laplace transform of t -*E|x(t)| is finite. We apply our results to the random harmonic oscillator and derive an explicit expression for the Lyapunov exponent. In a simple case it is computed by quadratures. Key words-* Lyapunov exponents, p-moment Lyapunov exponents, random evolution differential equations, random harmonic oscillator. AMS(MOS) subject classification: Primary 93E15, 34F05; Secondary 60J25, 70L05. Explicit expressions for the Lyapunov exponents of certain stochastic processes


More than 75% of Kenyans make some part of their living from agriculture and the sector accounts for more than fourth of Kenya's gross domestic product (GDP). Agriculture employs about 2 million people, and has been increased up to 21% of all agricultural exports. Despite of continuous population growth, agricultural productivity has gradually become stagnated in recent years. Only about 20% of Kenyan land found suitable for farming, and in these areas maximum yields have not been achieved, leaving considerable potential for increase in productivity. Quality planting material is one of the most important components for increasing the productivity. Tissue culture is proven technology to produce disease free and true to type quality planting material derived from the superior clone. It is noteworthy facts that India has demonstrated significant success in the area of commercial plant tissue culture. Government of India decided to share experience of Indian plant tissue culture to African countries and build capacity of nationals through training organized by BCIL in different modules. In spite of significant development for commercialization of plant tissue culture in Kenya, cost and quality of tissue culture plants remain major constrains in Kenya. India's experience in implementing the quality management system might be replicated to address these constrains which will facilitate realization of potential for Kenyan plant tissue culture.


The conventional method for measuring small objects in three dimensions utilising close range stereo photogrammatic techniques is complex and time consuming. A recent development called the Reflex Metrograph allows unskilled operator to collect three dimensional co-ordinates both simply and rapidly. A clinical application to compare in vivo and in vitro measurements showed a similar level of precision. The results compare favourably with a conventional approach.


Recent years have seen renewed attention focused on improving the legal and institutional frameworks governing water resources. This attention is being driven by a number of factors. Experience in trying to implement and enforce water laws in different countries has highlighted a number of gaps and conflicts in the laws at the local, national, and transboundary levels. These deficiencies are expected to be aggravated by the effects of climate change. At the same time, the last two decades have seen the development of new approaches for effectively managing water resources, including integrated water resources management (IWRM), adaptive management, decentralization, public-private partnerships, and participatory management. Increasingly, countries are incorporating these approaches into their water laws. Two articles in this issue explore weaknesses in the legal frameworks governing water resources in Colombia and Spain and propose means to address these weaknesses. Since many of the weaknesses are shared by other countries, the articles have broader relevance to countries that are trying to improve management of their surface and ground waters.


A study has been made of the petrology and geochemistry of a 30-mile (48.3 km) segment of a belt of ultramafic-gabbroic igneous bodies extending past the south side of Lake Abitibi, Ontario. In general, the bodies are sill-like and are differentiated into major layers of peridotite, clinopyroxenite, and gabbro, the layers generally being in that stratigraphic order. In detail, the intrusions fall into four groups: (1) complex sills in which there is a cyclic repetition of layers; (2) simple differentiated sills showing only one sequence of the above rock layers; (3) bodies composed only of peridotite and dunite; and (4) bodies composed wholly of gabbroic rocks.One of the group (2) bodies has a chilled margin equivalent in composition to a tholeiitic basalt. The general structure of the intrusions and their petrographic and chemical features indicate that they are differentiated from basaltic magma by gravity-controlled fractionation. However, it appears that while solidifying, some of the intrusions were ...


This thesis provides an examination of the ideology and experiences of postWorld War 11 Dutch Calvinist immigrants in British Columbia's Fraser Valley. These immigrants experienced a way of life that distinguished them from many other immigrant groups. In focusing on the community they created, this thesis provides a revision of previous views of the experience of Dutch immigrants in Canada, which assert that the Dutch are disappearing as a distinguishable ethnic group in Canada. This thesis argues that Dutch immigrants in Canada must first be examined with respect to their distinctive religious backgrounds; only with this facet of their lives in focus, can their experiences in Canada be understood. For the many Dutch Calvinist immigrants in Canada, religion was a dominant factor in the forces behind their emigration, the location of their settlement, and the degree of their Canadianization. Although a Dutch community as a whole does not exist in Canada, a strong Dutch Calvinist community does exist, built almost entirely in the post-war era. Many of these Calvinist immigrants arrived seeking economic security. However, after immigration, religious values became of paramount concern, leading them to create an environment in which they could achieve their ideals a covenant community. Conservative, highly religious and largely rural, the members of this community were distinct both from Dutch immigrants of other religions and from the wider Canadian society. Their inherent conservativism, redoubled by a defensive reflex against change after immigration, allowed them to create the institutional and personal boundaries they deemed necessary to preserve their way of life. The importance of three institutions, the church, the school and the home, explains far better than any link to other Dutch immigrants the strength and presence of this 'ethnic' community. Through these institutions the Dutch Calvinists in Canada were able to maintain their traditional way of life more successfully than either their original community in the Netherlands or the older communities of similar origin in the United States. By


In recent years, many commentators have noted the "illusory" nature of the death penalty in the United States, observing that, while the penalty is perceived to be broadly applied, it is in fact rarely imposed.1 Indeed, over the last decade there has been a marked decline in the number of death sentences imposed across the nation: 106 offenders were sentenced to death in 2009, compared to the approximately 300 sentenced to death each year in the mid-1990s.2 Yet, while death sentences have waned nationwide, state legislatures have crafted broad capital sentencing statutes designed to execute large numbers of defendants. In most states, a defendant cannot be eligible for the death penalty unless a jury finds that a statutorily enumerated aggravating factor applies to the defendant's case.3 However, the number and breadth of these aggravating factors have expanded over the last few decades, with most states listing more than ten factors, such that more than 90% of murderers are death eligible in many states.4 Thus, although most states sentence a small number of individuals to death each year,5 their death


In this article, we study activity recognition in the context of sensor-rich environments. We address, in particular, the problem of inductive biases and their impact on the data collection process. To be effective and robust, activity recognition systems must take these biases into account at all levels and model them as hyperparameters by which they can be controlled. Whether it is a bias related to sensor measurement, transmission protocol, sensor deployment topology, heterogeneity, dynamicity, or stochastic effects, it is important to understand their substantial impact on the quality of activity recognition models. This study highlights the need to separate the different types of biases arising in real situations so that machine learning models, e.g., adapt to the dynamicity of these environments, resist to sensor failures, and follow the evolution of the sensors topology. We propose a metamodeling process in which the sensor data is structured in layers. The lower layers encode the various biases linked to transformations, transmissions, and topology of data. The upper layers encode biases related to the data itself. This way, it becomes easier to model hyperparameters and follow changes in the data acquisition infrastructure. We illustrate our approach on the SHL dataset which provides motion sensor data for a list of human activities collected under real conditions. The trade-offs exposed and the broader implications of our approach are discussed with alternative techniques to encode and incorporate knowledge into activity recognition models.


basic strategies for narrative preaching, although one might question some of his advice, as was the case with his earlier work Homiletic. For instance, here Buttrick repudiates the notion of retelling a modem version of any given parable: "What equivalent will we find for a Jewish boy tending pigs? As for the father's wild hullabaloo of a welcome, can we find parallels that will be as undignified, unwise, and bizarre?" (41). The obvious answers are none and no, but must contemporary versions of a parable parallel Jesus' story at every point? What about a modem story that parallels the parable at its core point? . Buttrick's own preference entails preacher and listeners alike overhe~r ing the story, albeit interspersed With brief illustrative vignettes (41). He prefers that preachers stay in the parable as much as possible, interpreting it occasionally with contemporary metaphor (42-43). In his own sample sermons, these excursions typically comprise an anachronistic retelling. Most helpfully, the author encourages us to wrestle with where we are in the parable, hearing it shockingly for the first time or calmly reflecting on the familiar story before us (45). In perhaps the most revealing line in the book, he writes: "Our sermons must be designed to deconstruct the social world in which we live and open sudden glimpses of another world, the real world, God's world" (38). In this one sentence, he reminds us preachers of the theological nature of preaching, offering glimpses into God's world (what he elsewhere Book Reviews Review and Expositor, 97 (2000)


While matrix estimation is a standard process employed in many transportation studies and analyses, the process is used here to assist in model development and guide calibration efforts for a freight component within an existing travel demand model. Utilizing origin-destination matrix estimation (ODME) to create an observed truck trip table, with observed truck counts as constraints, the seeded and ODME-estimated matrices were compared to identify where the existing model was not replicating trips accurately. Trip generation rates were modified to reflect the percent change between the ODME-estimated and existing model trip tables for those origin-destination (O-D) pairs that were adjusted during the ODME process. Furthermore, trip distribution parameters (friction factors and highway skims) were adjusted to better match trip length frequency distributions of the ODME-estimated assigned truck trips. Use of the matrix estimated O-D trip table has led to significantly improved validation statistics, reducing the percent error for total truck trips from -57% in the existing model to -3% after trip generation and distribution modifications based on ODME adjustments, as well as expediting the calibration process.


6 Abstract: The batteries power life is play an important role in the in wireless sensor networks (WSNs), so that energy saving of its is a very critical issue. The limitation of transmission/reception of data should be as much as possible, it reduce the cause of power consumption in a sensor node. In the current cinereous the scalability problem of client/server model has been solved with the help of mobile agents for data fusion in wireless sensor networks. In this paper, we propose new communication architecture for group-based sensor networks based on agents' cooperation as the Visiting Center Local (VCL). This architecture uses techniques from multiagent system technology (MAS) and networks in order to ensure an optimal information gathering.Simulation results have approved that using multi-agent system and mobile agents in large scale WSNs show the ability of the proposed harvesting regime to prolong the network lifetime, in terms of energy consumption.


A nonlinear dynamic model is developed to analyze the bouncing vibration of a partial contact air bearing slider, which is designed for the areal recording density in hard disk drives of 1 Tbit/in2 or even higher. In this model the air bearing with contact is modeled using the generalized Reynolds equation modified with the Fukui-Kaneko slip correction and a new second order slip correction for the contact situation [1]. The adhesion, contact and friction between the slider and the disk are also considered in the model. It is found that the disk surface roughness, which moves into the head disk interface (HDI) as the disk rotates, excites the bouncing vibrations of the partial contact slider. The frequency spectra of the slider's bouncing vibration have high frequency components that correspond to the slider-disk contact.Copyright © 2007 by ASME


B-21, in: B.C. Alleman and M.E. Kelley (Conference Chairs), In Situ and On-Site Bioremediation—2005. Proceedings of the Eighth International In Situ and On-Site Bioremediation Symposium (Baltimore, Maryland; June 6–9, 2005). ISBN 1-57477-152-3, published by Battelle Press, Columbus, OH, www.battelle.org/bookstore. Biodegradation of Weathered Hydrocarbons in Laboratory Microcosms and Soil Columns Simulating Natural Attenuation Field Conditions C. Robin Cunningham and Y.M. Nelson (firstname.lastname@example.com) (California Polytechnic State University, San Luis Obispo, CA) P. Lundegard (Unocal Corp.) Controlled laboratory microcosms and soil columns were used to quantify biodegradation of weathered hydrocarbons in groundwater under conditions mimicking natural attenuation field conditions at a former oil field near Guadalupe, CA. Diesel range oil (DRO) was used as a diluent during oil production at this site from 1950-1991 to facilitate pumping the viscous crude oil. Leaking tanks and pipes resulted in hydrocarbon source zones and groundwater plumes. Following more aggressive treatments such as excavation, the feasibility of using natural attenuation to monitor the levels of diluent is currently being investigated using native microbial species. A laboratory study was undertaken using soil columns with soil and groundwater from the site and carboys with groundwater and no soil to ascertain the degradation kinetics and to ultimately evaluate the relative contributions of the local microbial species to bioremediate hydrocarbons under conditions more closely matched to site conditions than previous studies. Also of interest was the sustainability of biodegradation over long periods of time as well as changes in toxicity during biodegradation. Laboratory soil columns were set up using three sets of three vertical soil columns in series filled with soil from the field site. Groundwater from the site with an initial total petroleum hydrocarbon (TPH) concentration of 2.3 ± 0.1 mg/L was recirculated through the column with the same Darcy velocity as observed in the field. Microcosms were set up in duplicate 12-L carboys with no soil. The microcosms were filled with the same groundwater as collected for the soil columns and were stirred constantly and aerated. Biodegradation rates were determined by monitoring the (TPH) concentration during simultaneous 150-day experiments. Toxicity was monitored using Microtox Vibrio fischeri bacteria. Dissolved oxygen, pH, nutrient levels (SO4, NO3, NO2, NH3 & PO4) and total organic carbon (TOC) were also monitored. TPH biodegradation was most rapid during the first 20 days. After 150 days TPH concentration decreased to 0.76 ± 0.0 mg/L in the soil columns and to 0.88 ± 0.156 mg/L in the carboy microcosms. The faster biodegradation in the soil columns was statistically significant with 95% confidence. The TPH concentration in an azide-inhibited control actually increased to 4.6 ± 0.0 mg/L. Since TPH did not decrease in the azide-inhibited control adsorption onto soil particles is unlikely and observed TPH loss in the soil columns can be attributed to biodegradation by bacterial cells. Microtox toxicity rapidly decreased to below detection limits within 30 days. These results suggest that natural attenuation is feasible at this site.


Different approaches can be undertaken to realise a stereoselective electrochemical synthesis. Significant contributions to enantioselective electrochemical organic synthesis have been reported and largely reviewed in recent years. However, the development of general strategies for the electrochemical enantiocontrol of a transformation still presents considerable challenges; in particular, relatively few contributions of highly enantioselective catalytic electrochemical reactions have been reported to date. In this review article, the most recent examples of asymmetric electrochemical catalysis are discussed. The article is organised by the three types of enantioselective catalysis: metal-based catalysis, organocatalysis and biocatalysis; in each section, the most significant and recent advances are presented and discussed.


The present investigation was carried out at AICRP on Floriculture, Horticulture Farm, RCA Campus, MPUAT, Udaipur to find out field performance 13 tuberose cultivars with respect to growth, floral and economic parameters. The maximum values for plant height (91.67 cm), leaves plant−1(43.50), bulbs plant−1 (50.0), bulb weight plant−1 (727.50g), spike length (74.90 cm), peak flowering duration (21.83 days), vase-life in plain water (7.83 days), spikes plant−1 (3.02), florets spike−1 (53.17), florets remaining open at a time (6.17), floret size (4.73 cm), spike weight (118.30 g), net returns (Rs. 5,60,514/-)/ha and benefit: cost ratio (Rs. 2.69) were recorded in cv. Prajwal followed by Phule Rajani in single type cultivars. However, in double type tuberose cultivars tallest plant (85.67 cm), leaves plant−1 (42.33), bulbs plant−1 (48.67), bulb weight plant−1 (739.50 g), spike length (75.62 cm), peak flowering duration (32.92 days), vase life in plain water (7.57 days), spikes plant−1 (2.90), florets spike−1 (49.83), florets remaining open at a time (6.83), floret size (4.58 cm), spike weight (109.33 g), net returns (Rs. 5,21,292/-)/ha and benefit: cost ratio (2.52) were obtained in cv. Suvasini followed by Vaibhav. On the basis of observations recorded for growth, floral and economics parameters cv. Prajwal in single and Suvasini in double type of tuberose recommended for cut flowers and exhibition purposes under Udaipur conditions.


Solid-supported lipid bilayers hold strong promise as bioanalytical sensor platforms because they readily mimic the same multivalent ligand-receptor interactions that occur in real cells. Such devices might be used to monitor air and water quality under real-world conditions. At present, however, supported membranes are considered too fragile to survive the harsh environments typically required for non-laboratory use. Specifically, they lack the resiliency to withstand air exposure and the thermal and mechanical stresses associated with device transport, storage, and continuous use over long periods of time. Several successful strategies are now emerging to make supported membranes tougher. These strategies incorporate mimics of the cytoskeleton and glycocalyx of real cell membranes. The promise of these more robust lipid bilayer architectures indicates that future materials should be designed to more fully resemble the actual structure of cell membranes.


The International Classification of Diseases (ICD) is a list of classification codes for the diagnoses. Automatic ICD coding is a multi-label text classification problem with noisy clinical document inputs and long-tailed label distribution, making it difficult for fine-grained classification on both frequent and zero-shot codes at the same time, i.e. generalized zero-shot ICD coding. In this paper, we propose a latent feature generation framework to improve the prediction on unseen codes without compromising the performance on seen codes. Our framework generates semantically meaningful features for zero-shot codes by exploiting ICD code hierarchical structure and reconstructing the code-relevant keywords with a novel cycle architecture. To the best of our knowledge, this is the first adversarial generative model for generalized zero-shot learning on multi-label text classification. Extensive experiments demonstrate the effectiveness of our approach. On the public MIMIC-III dataset, our methods improve the F1 score from nearly 0 to 20.91% for the zero-shot codes, and increase the AUC score by 3% (absolute improvement) from previous state of the art. Code is available at https://github.com/csong27/gzsl_text.


Magnetic resonance elastography (MRE) can determine the presence and stage of liver fibrosis. Data on normative MRE values, while reported in adults, are limited in children.


We propose an easy and simple method that deforms a 3D model in VR. The proposed method easily manipulates 3D models which are difficult to handle in VR environment by using semantic shape deformation technique and NUI which is easy to operate with one hand. CCS Concepts •Computer Graphics → Graphics systems and interfaces;


According to logic problems due to the imperfect in DCS and its processes during the on-site commissioning process and after into the formal commercial operation of the 2×660 MW supercritical generating units in Jingdezhen Power Plant of China Power Investment Corporation Jiangxi Branch, and also in accordance with the plant's actual situation, the improvement measures are advanced and its implement effects are elaborated, wanting to have some reference in the debugging and production of the similar units.


It's a powerful book. Tennent ''Pete'' Bagley's Spy Wars: Moles, Mysteries and Deadly Games is like none we've read before. It rocks the Central Intelligence Agency (CIA) with the Yuri Nosenko affair that occurred over forty years ago but whose black specter still hangs over Langley and won't go away. Reading provides a r e a l u n d e r s t a n d i n g o f w h y Mr. Bagley, a major player, writes from deep inside. I looked forward to reading Bagley's book as Nosenko had an unsolved, mysterious role in the investigation of President John F. Kennedy's assassination on 22 November 1963. But Spy Wars is more than that . I t i s the bes t detailed account of the incredible capabilities of the Soviet Union's KGB. I wondered whether any just, humane nat ion could tolerate having an intelligence service so good it could kill, kidnap, torture, and jail people in freezing gulags w i t h a b s o l u t e i m p u r i t y a n d immunity.


A business model is a sustainable way of doing business. Here sustainability stresses the ambition to survive even harsh business landscapes and create profits in the long run. Whether profits are retained by the shareholders or distributed in some degree to a broader mass of stakeholders is not the focus here. Rather, it is the point of this paper to illustrate how one may go about conceptualizing, analyzing and communicating the business model of a company. A business model describes the coherence in the strategic choices which makes possible the handling of the processes and relations which create value on both the operational, tactical and strategic levels in the organization. The business model is the platform which connects resources, processes and the supply of a service, which results in the fact that the company is profitable in the long term. Conceptualizing the business model is therefore concerned with identifying this platform, while analyzing it is concerned with gaining an understanding of precisely which levers of control are apt to deliver the value proposition of the company. Finally, communicating the business model is concerned with identifying the most important performance measures, both absolute and relative measures, and relating them to the overall value creation story.


: In view of the wide variety and quantity of mechanical equipment spare parts, the increasing difficulty of spare parts management, and how to accurately predict the demand for spare parts, the least squares support vector machine (LS-SVM) regression algorithm is proposed to predict the demand for mechanical equipment spare parts. Based on the analysis of the basic principle of least squares support vector machine, a prediction model of mechanical equipment spare parts demand is established. RBF kernel function is selected. LS-SVM is used to study the training samples, train its grid structure parameters, determine the optimal parameters through cross validation and grid search, and use the trained LS-SVM to predict the mechanical equipment spare parts demand, and carry out numerical simulation, The prediction methods such as first-order exponential smoothing, ARMA method and BP neural network are used for comparison. The results show that LS-SVM performs well in the demand forecast of mechanical equipment spare parts.


The heat capacity of deutero‐ammonium bromide has been measured from 17° to 300°K. The heat‐capacity curve is characterized by the appearance of two maxima. These are associated with polymorphic transitions in the crystal lattice and with the ordering of the ammonium ion tetrahedra with respect to the two equilibrium positions in the unit cell. The excess entropy associated with the maxima is found to be in agreement with the order‐disorder nature of the upper transition. A frequency of torsional oscillation for the ammonium ion in good agreement with infrared data is obtained from the Debye‐Einstein function representing the heat capacity below 100°K.


PurposeThis study aims to examine corporate sustainability in the hospitality industry as it caters to multiple stakeholders such as society and environment. Further, the researchers have attempted to portray a comprehensive outlook of corporate sustainability by examining the organizational-level and environmental-level drivers and assessing the impact of corporate sustainability on an overarching measure of hotel performance: sustainability balanced scorecard (SBSC).Design/methodology/approachA three-staged mixed-methods research design was implemented comprising interviews, surveys and a post-hoc analysis to test the comprehensive framework of corporate sustainability.FindingsThe authors observed that corporate sustainability positively impacted hotel performance. The results further indicated that in competing environments and presence of slack resources, sampled firms could develop their sustainability strategy to improve performance. Surprisingly, environmental munificence did not significantly influence corporate sustainability but directly increased hotel performance. Interestingly, hotel performance also improved upon having managerial commitment toward sustainability.Practical implicationsThe study highlights the crucial role of top management in hotels, where their commitment to sustainability can positively impact not just hotel's engagement in corporate sustainability but can also directly enhance hotel's overall performance. Hotel managers can utilize the SBSC developed in this study to comprehensively measure hotel performance which is found to be positively impacted by hotel's engagement toward corporate sustainability.Originality/valueThe study contributes to the sustainability literature by examining drivers of corporate sustainability in the Indian hospitality industry from two perspectives: environmental and organizational. With the escalating ambiguity of sustainability–performance relationship, the authors employed a novel technique for operationalizing hotel performance: SBSC.


Abstract Co-crystallization of 3-phenylazopyridine (3PAzP) with dihalogenated resorcinols (res) 4,6-diX res (where: X = Cl, Br, and I) yields co-crystals that support molecular pedal motion in the crystalline state. The co-crystals are sustained by hydrogen-bonded assemblies, with the pattern of hydrogen-bonding drastically different based on the res. For 4,6-diCl res, an unexpected eight-component hydrogen-bonded assembly is realized, while three-component hydrogen-bonded assemblies are observed for 4,6-diBr res and 4,6-diI res. We show the co-crystallization approach to afford pedal motion in the azo core, while no such motion is present in the absence of a res. Pure 3PAzP packs to form a noncentrosymmetric herringbone structure.


The invention relates to a pressure value display method of a manual electronic sphygmomanometer. The manual electronic sphygmomanometer comprises a manual pressurized air pump and an air charging component connected with the manual pressurized air pump. Air pressure in the air charging component is converted by a pressure sensor as well as calculated and treated by a microprocessor to obtain a real-time pressure value, and the microprocessor is connected with a display; in the pressure increasing phase inside the air charging component, the display displays the pressure value or a similar value inside the air charging component with a pressure value space of at least 2 mm Hg in an equidistant increasing mode; or in the non-pulse decompression phase inside the air charging component, the display displays the pressure value or a similar value inside the air charging component with a pressure value space of at least 2 mm Hg in an equidistant decreasing mode. The invention also provides the manual electronic sphygmomanometer which can display the pressure value with longer updating time delay and effective predictable property and is convenient for an operator to read the pressure value.


The induction motors are most widely used motors in industrial, commercial and residential sectors because of enormous merits of these over other types of available electrical motors. These motors work under various operating stresses, which deteriorate their motor conditions giving rise to faults. The early detection of these deteriorating conditions in incipient phase and its removal/correction is very necessary for the prevention of any external faults/failure of induction motors reducing repair costs and motor outage time. Fault detection using analytical methods is not always possible because it requires a perfect knowledge of the motor model. The artificial neural network techniques are rather easy to develop and to perform. These networks can be applied when the information about the system is obtained from measurements, which later can be used in the training procedures of the neural networks. Neural detectors can be designed from simulation or experimental tests. In the present paper the applicability/feasibility of artificial neural network (ANN) technique for the detection and identification of incipient faults in an induction motor has been explored. Radial basis function (exact fit) approach has been used for ANN training and test. The applicability of the graphical user interface (GUI) of neural network tool box under Matlab environment has been explored in this paper. The various types of faults have been considered. Three phase instantaneous voltages and currents are utilized in proposed approach. Simulated fault current and voltage data have been used for testing of trained network.


In the fall of 1994, a trial was initiated to assess the survival of Ascochyta lentis Vassil. on naturally infected lentil (Lens culinaris Medik.) residue buried at 0-, 5- and 10-cm depth in a clay loam soil at Saskatoon, Sask. Samples were collected and assessed from 1995 to 1998, with six replicates for each depth × sampling date combination. After collection, the material was air dried, divided in half (by mass), and assessed using a plating and a bioassay technique. Results from both techniques were similar. Inoculum levels in the spring of 1995 were almost an order of magnitude higher than the previous fall, indicating that the pathogen had spread in the infected residue. Inoculum potential declined slowly over the course of the trial, but the pathogen was still present and infectious (although at low levels) in the residue almost 4 years after harvest. There was a consistent pattern of seasonal fluctuation in the level of A. lentis in infected residue: levels were higher in spring than in the previous fall. Contrary to previous reports, burial did not have a substantial impact on the long-term survival of A. lentis.


ABSTRACT — Deprenyl inhibits MAO‐B selectively in different animal species and in man. Its safety margin is remarkable. We were able to block MAO‐B activity in the brain selectively in vivo in four species (mouse, rat, cat, dog) with s.c. administration of 0.17–0.31% of LD50. The usual oral dose range in clinical practice, 5–20 mg daily (0.05–0.2 mg/kg), is about ten times lower than the orally active dose in the rat.


Consider a universal oracle Turing machine that prints a finite or an infinite binary sequence, based on the answers to the binary queries that it makes during the computation. We study the probability that this output is infinite and computable when the machine is given a random (in the probabilistic sense) stream of bits as the answers to its queries during an infinitary computation. Surprisingly, we find that these probabilities are the entire class of real numbers in (0,1) that can be written as the difference of two halting probabilities relative to the halting problem. In particular, there are universal Turing machines that produce a computable infinite output with probability exactly 1/2. Our results contrast a large array of facts (the most well-known being the randomness of Chaitin's halting probability) that witness maximal initial segment complexity of probabilities associated with universal machines. Our proof uses recent advances in algorithmic randomness.


The marketing mix consists of all the things a company can do to find out the demand for its products. This research was aimed to analyze the application of the 9P marketing mix strategy in increasing sales volume as an effort to maximize profits in the Abdul Ghoffar Rejotangan Tulungagung's Koi Fish Farming Business. This research used descriptive research methods and STP with a qualitative approach. Sources of data in this research were primary and secondary data. Data collection techniques used observation, interviews, questionnaires, and documentation. The research was carried out with 5 informants, they were business owners, employees, consumers 1, consumers 2, and competitors. The results showed that the 9P marketing mix strategy at the Abdul Ghoffar Rejotangan Tulungagung's Koi Fish Farming Business was carried out in various ways. First, the various products produced with 11 kinds of fish, good quality products concerning the size of the koi fish, and innovative products. Second, the price offered was affordable according to the target market. Third, marketing and delivery locations were strategic and easy to reach. Fourth, various promotions so prospective consumers could easily find products. Fifth, good quality business locations by classifying fish according to conditions. Sixth, conducted training for employees to produce good service to consumers. Seventh, an effective delivery process by choosing the right distributor. Eighth, did safe packaging. Ninth, used an easy payment method. This research concluded that the implementation of the 9P marketing mix strategy can have an impact on increasing sales volume in Abdul Ghoffar Rejotangan Tulungagung's Koi Fish Farming Business.


Scientific research in Africa (and its impact on development) is a growing preoccupation of African decision-makers and money lenders. The recent establishment of several programmes to support research, particularly in the area of agriculture activities, is indicative of this situation. What is the current state of scientific research in Africa and what are the main factors limiting its functioning and development ? After an historical review of the African scientific apparatus, this article sets out to provide an answer to this question by analyzing the available resources, production, visibility and utility indices of science in Africa. It also reveals the existing structures and the constraints facing researchers, before tackling the fundamental issue: what are the prerequisites for the formation of autonomous scientific communities in Africa ? Keywords; Sciences, scientific research, medical research, agricultural research, science policy, researcher, aid to research, research institutions. Sub-Saharan Africa. ì


Contrary information is recorded in the process of Ribonucleic Acid transcription, which is similar to the anti-synchronization process. In this paper, the anti-synchronization of coupled Boolean networks is investigated. Firstly, the definition of anti-synchronization is introduced, and the drive-response Boolean networks dynamics are translated into linear representations with the semi-tensor product. Then, a necessary and sufficient condition is obtained for anti-synchronization of coupled Boolean networks. Finally, simulation example is presented to further illustrate the efficiency of the proposed method.


This is a non-partisan review of the major sociological theories of crime and deviance. It begins with the work of the "Chicago School" of the 1920s and proceeds chronologically through the main theoretical positions to reach contemporary work on "Left Realism" and feminist criminology. The principal aim is to introduce students to ideas in a manner that is clear and accessible but not biased. The strengths and weaknesses of each theory are assessed so that the reader is able to make an informed judgement about its worth.


Objective) Nurses working night shifts experience great stress due to the disturbance to their circadian rhythm and exhibit many health problems, including sleep disturbance. We sought to examine the clinical efficacy of ear acupuncture (EA) for their sleep problems. (Methods) In this open trial, wrist actigraphy and structured questionnaires were used to determine their sleep/wake patterns and psychosomatic conditions. The 17 female nurses performed shift work at night in wards with chronic invalid patients in three different hospitals. The data for their sleep/wake patterns were recorded in the first week as a control and, in the next week, these data were recorded during EA treatment. Intradermal needles were inserted at the two points of the auricle, innervated by the great auricular nerve (C2, 3).


We construct a p. i. algebra A with condimension sequence c n (A) asymptotic to αn 425 n , where α lies in the field , but not in any quadratic extension of .


In this month ' s journal Ahn and colleagues 1 report the effect of arm abduction on the success of central catheter placement afterultrasoundguidedinfraclavicularaxillaryvein(AXV)cannu-lation. We discuss these fi ndings and re fl ect on the development of this particular route of access to central veins. This paper presents good evidence that arm abduction in-creases the success of central catheter placement with this approach from the right side and therefore reduces one problem of this procedure. This has parallels with peripherally inserted central catheters (PICC) placement where it is routine to put arms out on a board, 2 albeit primarily to aid vein access on the medial aspect of the upper arm. The malposition rate when the AXV was punctured in the neutral position and was signi fi cantly higher than with the arm abducted. Itis suggestedthatarm abduction opened upthe curve between the subclavian vein and superior vena cava (SVC) to aid central passage of the guidewire. Interestingly there were four arterial punctures in the neutral group but none in the abducted group, which might also suggest abduction favourably altered either the size of the vein, or its degree of overlap with the artery. This was not measured by the authors. There are other measures to reduce or correct misplacement of central venous catheters. These include:


The invention discloses a kind of carborundum based material and inhale ripple heater composition and method of making the same, this heater composition is by 75 parts ~ 95 parts hosts, 5 parts ~ 25 parts modifier; 1 part ~ 6 adding additives especially, 5 parts ~ 50 parts water compositions; Prepare this carborundum based material and inhale the method for ripple heater, comprise the following steps: ball mill mixing; Old; Moulding; Dry; Sintering. Carborundum based material of the present invention is inhaled ripple heater, has good absorption microwave fast heating performance at civil band (2.45G hertz). This suction ripple heater can need to be processed into various shapes according to sintered products, and production technology is simple, production cost is low, serviceability temperature wide ranges, high-temperature oxidation resistance are good, of many uses, easily form different atmosphere, can meet the requirement of dissimilar product sintering, is extensively used as the heater element of various high temperature furnaces.


Over recent years, tensors have emerged as the preferred data structure for model representation and computation in machine learning. However, current tensor models suffer from a lack of a formal basis, where the tensors are treated as arbitrary multidimensional data processed by a large and ever-growing collection of functions added ad hoc. In this way, tensor frameworks degenerate to programming languages with a curiously cumbersome data model. This paper argues that a more formal basis for tensors and their computation brings important benefits. The proposed formalism is based on 1) a strong type system for tensors with named dimensions, 2) a common model of both dense and sparse tensors, and 3) a small, closed set of tensor functions, providing a general mathematical language in which higher level functions can be expressed. These features work together to provide ease of use resulting from static type verification with meaningful dimension names, improved interoperability resulting from defining a closed set of just six foundational tensor functions, and better support for performance optimizations resulting from having just a small set of core functions needing low-level optimizations, and higher-level operations being able to work on arbitrary chunks of these functions, as well as from better mathematical properties from using named tensor dimensions without inherent order. The proposed model is implemented as the model inference engine in the Vespa big data serving engine, where it runs various models expressed in this language directly, as well as models expressed in TensorFlow or Onnx formats.


The current system of judicial review in U.S.is the modern version,while its early phase is considered as both a revolutionary action opposing legislative despotism and a political action.The Marshall Court fostered judicial review to a traditional phase from the early phase.Judicial review gained much features of law and became part of court's daily routine.The transitional phase came in the late of the nineteenth century,when the court adopted substantive due process to review legislations on economy.The transitional phase expected the coming of modern judicial review.The change of constitutional and judicial notions,the constitutional revolution in 1937 and the Warren Court pushed forward together the modern judicial review,with the feature that the role of judicial departments in American political activities are more clearly accepted.Since then the judicial legislation is the judge's essential responsibility which cannot be shirked off.


Unlike archiving most other artifacts and objects, film preservation has always been heavily dependent on industry practice. The complicated and vast machinery involved in shooting, duplication, processing and projection of new films has been the same ones used for preserving and presenting film heritage. The recent shift from analogue to digital technology in capture, post-production and distribution of cinematographic works has led to the biggest challenges ever faced by the global archive community. The digitization of heritage films has the potential of providing access on an unprecedented scale, as new platforms have emerged to facilitate access and the fact that digital copies are not subject to same wear and tear as analogue film elements. But there are severe financial, legal, curatorial and technological challenges to overcome in order to fulfill this potential. The industrial shift to digital technology has led not only to dwindling photochemical laboratory capacity, film stock supply and 35mm projection equipment, which threatens the preservation and access to film heritage in original formats, but also to declining demand for scanning equipment, resulting in the fact that the window of opportunity for high-quality digitization of analogue films is already closing. Unless necessary funding is put in place very soon, 115 years of film heritage may become forever inaccessible in the future.


hectare. One of the intrinsic rules to address the issues of urban hygiene and comfort that have been at the heart of the grid of modern urbanism.In El Khroub, the second city in the ring bordering the city of Constantine, one of the major cities of eastern Algeria, the no-man's land occupies more than 33.5% of its land base, the equivalent of 171.25 ha. The present work aims to trace the genetic movement of no-man's-land spaces, identify them in their urban problems, and more particularly understand the relationship between urban policy in Algeria and its emergence based on two factors: rehousing operations and the neglect of the role of the inhabitants in the production process. Our object of study is the phenomenon of urban no-man's-land, which refers to all forms of empty, uninhabited, residual, and unoccupied spaces. This phenomenon is observed on several urban scales in the New urban housing areas across the city of El Khroub belonging to the urban area of the city of Constantine located in eastern Algeria. The objectives of this research are to examine this multi-dimensional phenomenon and to understand the dynamics and factors of the emergence of no man's land in cities through urban policies based on several approaches, methods, and tools. The historical and analytical approaches form the basis of the study. The survey method integrates the participation of citizens via non-participant observation techniques, as well as a multiple-choice questionnaire interview.


Fast and efficient processor allocation and job scheduling algorithms are essential components of a multi-user multicomputer operating system. In this paper we propose two novel processor management schemes which meet such demands for mesh-connected multicomputers. A stack-based allocation algorithm that can locate a free sub-mesh for a job very quickly using simple coordinate calculation and spatial subtraction is proposed. Simulation results show that the stack-based allocation algorithm outperforms all the existing allocation policies in terms of allocation overhead while delivering competitive performance. Another technique, called group scheduling, schedules jobs in such a way that the jobs belonging to the same group do not block each other. The groups are scheduled in an FCFS order to prevent starvation. This simple but efficient scheduling policy reduces the response rime significantly by minimizing the queueing delay for the jobs in the same group. These two schemes, when used together can provide faster service to users with very little overhead.


Cellular networks are a way of long distance communication without the use of cables, this system is a modern style of communication that was previously communication using a landline-based telephone. Cell phones (cellphones) or cell phones (cellphones) are electronic-based telecommunications devices that have the exact same basis as telephone telecommunications devices using cables or wireless wireless. The use of cellular or wireless phones is very useful, but in certain conditions their use can be limited because it can interfere with people around him such as the implementation of worship, examinations, meetings and so forth. To answer complaints about how to reduce cell phone and wireless signals, a tool that is able to deactivate GSM and Wi-fi cell phone signals at certain radii will use a jammer, a device that works by emitting full noise signals at 900 MHz frequency banks, 1800 MHz and 2700 MHz, so that the communication device cannot be used until the time limit and the distance of the radius that reaches the communication device. The results of this study have been successfully carried out by deactivating cell phone and wireless signals at a maximum distance of 7 meters from the jammer.


The influence of reverse cyclic loading at 4.16 Hz on both bond slip and the consequential rise in temperature has been studied experimentally for three reinforced concrete beams. The beams, 5 m long with rectangular cross-section, 0.25 X 0.4 m deep, and equally reinforced in both flanges, were subjected to cycles of reverse loading about a mean bending moment for increasing values of applied moment, up to a maximum of ultimate moment capacity. Rises in temperature of up to 13 degrees C were recorded close to cracks in the concrete. Strains were recorded in the region of maximum moment using both slotted and surface gauges. A simple method for calculating maximum deflections during cyclic loading is shown to be effective for the tests reported here. (TRRL)


Abstract Studies on seaport operations emphasize the fact that the numbers of resources utilized at seaport terminals add a multitude of complexities to dynamic optimization problems. In such dynamic environments, there has been a need for solving each complex operational problem to increase service efficiency and to improve seaport competitiveness. This paper states the key problems of seaport logistics and proposes an innovative cross‐entropy (CE) algorithm for solving the complex problems of combinatorial seaport logistics. Computational results exhibit that the CE algorithm is an efficient, convenient and applicable stochastic method for solving the optimization problems of seaport logistics operations.


Title of dissertation: ELGAR AND MART&: THE CELLO WORKS AND MUSICAL CHARACTERISTICS OF TWO REMARKABLE, SELF-TAUGHT, NATIONALISTIC COMPOSERS Kichung Bae, Doctor of Musical Arts, 2006 Dissertation directed by: Professor Evelyn Elsing School of Music The British Edward Elgar and Czech Bohuslav MartinB were two of the most prominent Nationalistic composers of their respective countries during the late nineteenth and early twentieth centuries. Their musical patriotism incorporates the unique paths of their lives as socially isolated and self-taught composers as expressed in their outstanding Nationalistic compositions produced through the period of history encompassing the two World Wars. In the first chapter of this dissertation, a brief biography of Elgar is presented and the essential aspects of his formative years influencing him to become a self-taught musician are discussed. The second chapter demonstrates Elgar's musical characteristics through the study of a selection of his masterpieces. In the third chapter, a brief biography of Martinti is presented along with a history of his musical development, characterized by his social isolation during four different periods of his life-his residences in PoliCka, Prague, Paris, and then in the United States. The fourth chapter considers MartinB's musical characteristics as revealed through the study of a selection of his greatest works. In support of this doctoral project, I performed two recitals of cello works by Elgar and Martini3 at the University of Maryland, College Park. The first recital, accompanied by Susan Slingland and Hiroko Yamazaki, included three of Martini3's works, Sonata No. 2 for Cello and Piano (1941); Variations on a Theme of Rossini for Cello and Piano (1 942); and Sonata No. 3 for Cello and Piano (1952). The second recital, accompanied by Wonyoung Chang and Naoko Takao, presented Martini3's Sonata No. 1 for Cello and Piano (1939) and Elgar's Concerto for Cello and Orchestra Op. 85 in E minor (1 919). ELGAR AND MART&: THE CELLO WORKS AND MUSICAL CHARACTERISTICS OF TWO REMARKABLE, SELF-TAUGHT, NATIONALISTIC COMPOSERS


Reliability is a key issue in the design and operation of power distribution system. Reliability indices such as SAIDI and SAIFI measure the overall reliability of the system which can be used to establish or optimize the maintenance strategies for distribution system. However, calculating these indices are challenging due to the availability of appropriate and sufficient information and data. One of the basic inputs for calculation of reliability indices is the number of the customers which have been affected per each interruption. In some cases the undistributed energy for each interruption and average customer's consumption can be used to calculate the number of customers per each interruption. In this study such approach is illustrated by a case study


The misunderstandings of and the bias against the concept law theory have caused our misin-terpretations of some of the legal concepts. When we are trying to defend the concept law theory, we have found that the different understandings of legal concepts have been the sources of the conflict be-tween legality and justice. So, the question of interpreting legal concepts has been the essential problem of the rule by law


The decomposition of the surface formate on Ni(110) was studied by temperature programmed desorption (TPD) and timeresolved infrared reflection absorption spectroscopy (TR-IRAS). It was observed that dehydration proceeded simultaneously with dehydrogenation. The rate-determining step of dehydration was found to be the C-H bond cleavage of formate as is the case of dehydrogenation by analysis of the kinetic isotope effect using HCOO(a) and DCOO(a). These results suggest that the rate-determining steps of dehydration and dehydrogenation are common. We propose a mechanism in which the CO2(a) species formed via the C-H bond cleavage of formate acts as the intermediate not only for dehydrogenation but also for dehydration; dehydration takes place by dissociation of the C-O bond of CO2(a).


Case 2. Following a fall down a crevasse (>40 m) in the ablation area of the Gurglerferner (Oetztal Alps, Tyrol) at approximately 2800 m a.s.l., the casualty was discovered on the glacier surface in 1973, about 150 m below the scene of the accident. The fa tal accident occurred in 1965 and the corpse had been immersed in glacier ice for 8 years. Flow path and time of flow movement yield a velocity of approximately 20 m year-I. Considering the size of the Gurglerferner (length 6.5 km, maximum width 3.0 km, depth at the accident site '" 140 m), this value seems consistent with glaciological measurements (Schneider, 1970).


The article is devoted to the problem of studying the personal orientation, terminal, instrumental and social values of students, future psychologists and mathematicians. The following methods were used in the study: «Orientative questionnaire» by V. Smekalov and M. Kucher, revealing the peculiarities of the person's orientation towards himself, on interaction, on performing the task; the method «Value Orientations» by M. Rokich, revealing the hierarchy of terminal and instrumental values; «Express diagnosis» of the social values of the individual. The article presents the results of researching of the personality orientation, terminal, instrumental, and social values of students-psychologists and students-mathematicians. A comparative analysis of the results of research of the orientation of the personality and values of student psychologists and students-mathematicians was carried out using the statistical method of studying «T-criterion of Student» Based on the analysis of the results of the study, conclusions are drawn about the differences in the orientation of the personality and values of students-psychologists and students-mathematicians.


With the development of mobile communication technology and the complexity of communication networks, the coverage area of base stations decreases and the demand becomes larger. In this paper, a corresponding planning model is established and an intelligent optimization algorithm is used to solve the problem. Firstly, the data are cleaned and denoised, and the data that do not meet the requirements are eliminated by calculating the Euclidean distance between the existing network base stations and the weak coverage points. Then the K-means algorithm is used to cluster the samples according to the coverage of the base stations. Then a planning model is established and solved using a hierarchical coevolutionary immune algorithm to finally calculate the number of base stations that need to be built. When the coverage of the base station changes from the center of a circle to an angle-limited sector. A functional analysis is performed for the coverage of the base stations. Using linear interpolation, the relationship between the coverage radius and the angle of the base station direction is obtained. The planning model is established by taking the sector coverage angle in the main direction as a constraint. The maximum coverage of a single base station that can be obtained at an angle of 120° is obtained, and it is found that the coverage decreases under the actual condition compared with the previous one.


Coriander (Coriandrum sativum L.) is most popular seed spice crops cultivated across India and can be considered as indispensable spice in the kitchen. Crop productivity is affected by the seed quality which determine the seed germination, vigour and viability. The experiment was conducted in the Research Farm of the Department of Vegetable Science, CCS Haryana Agricultural University, Hisar during rabi season in the year 2018-19 to evaluate the performance of thirty coriander genotypes for identifying the suitable genotypes with higher seed quality. A wide range of variation and significant differences were reported among the genotypes for the six seed quality traits viz, test weight (g), standard germination (%), seedling length (cm), seedling dry weight (g), seed vigour index-I and seed vigour index-II. The assessment revealed that variation was highest for seed vigour index-I (1343.3-1903.3) followed by seed vigour indexII (107.2-198.0), standard germination (59.7-70.0), seedling length (22.1-28.2), test weight (8.313.4), while, it was low for seedling dry weight (1.8-2.8). The genotypes DH-306, DH-319, DH313-1, DH325 and DH-308 were identified as the superior genotype in respect of their seed quality parameters taken under observation and they can be used for further breeding programmes.


During his defence of C. Cornelius in 65 B.C. Cicero alleged that when С Manilius had been brought to trial earlier that year, he had broken up the court by violence at the instigation of magni homines1). Asconius identified the magii homines as Catiline and Cn. Piso. His identification, however, has been challenged by Gruen2) on two accounts: 1) Catiline and Piso were not sufficiently prominent to merit description as magii homines; 2) they were both hostile towards Pompey and are therefore unlikely to have collaborated with the Pompeian Manilius. Underlying Gruen's arguments is the tacit assumption that Asconius' identification is conjectural. Certainly, since Asconius says that Cicero seems to mean (uidetur significare) Catiline and Piso, it might be supposed that he was only guessing3). But he also uses this expression when noting the conflicting accounts given by Cicero of the part played by Scipio Africanus in the decision taken in 194 B.C. to set aside separate seats for senators at public games, although the qualification uidetur is in fact unnecessary4). In this passage the words uidetur significare probably serve no other purpose than to provide variety from the more usual significai It is quite possible that Asconius employed this expression for the same reason apropos of the maga homines, since he had used significai several times already in his commentary In Cornelianum. Consequently his identification can be shown to be a conjecture and an erroneous one at that only by adducing historical proof that Catiline and Piso cannot have been the magni homines referred to by Cicero. Gruen argues that, since Catiline was only of praetorian rank and Piso was a mere quaestor, Cicero would not call them magni homines. However, this is far from certain. Cicero usually applies magnus to persons as a term of praise, often in conjunction with another laudatory epithet6). He uses it to describe the


The role of the redox state of Kv subunits in the modulation of Kv1 potassium channels has been well documented over the past few years. It has been suggested that a molecule that binds to or inhibits the aldo-keto reductase activity of Kv might affect the modulation of channel properties. Previous studies of possible modulators of channel activity have shown that cortisone and some related compounds are able to physically dissociate the channel components by binding to a site at the interface between and subunits. Herein, we describe some new inhibitors of rat brain Kv 2, identified using an assay based on multiple substrate turnover. This approach allows one to focus on molecules that specifically block NADPH oxidation. These studies showed that, at 0.5 mM, 3,4-dihydroxphenylacetic acid (DOPAC) was an inhibitor of Kv 2 turnover yielding a ∼40–50% reduction in the aldehyde reductase activity of this subunit. Other significant inhibitors include the bioflavinoid, rutin and the polyphenol resveratrol; some of the known cardioprotective effects of these molecules may be attributable to Kv1 channel modulation. Cortisone or catechol caused moderate inhibition of Kv 2 turnover, and the aldo-keto reductases inhibitor valproate had an even smaller effect. Despite the importance of the Kv1 channels in a number of disease states, there have been few Kv 2 inhibitors reported. While the ones identified in this study are only effective at high concentrations, they could serve as tools to decipher the role of Kv 2 in vivo and, eventually, inform the development of novel therapeutics. © 2014 Published by Elsevier Ltd.


A 2-day-old preterm male infant with hemolytic anemia and indirect hyperbilirubinemia receiving intensive phototherapy presents with a rash.

### Prenatal and Birth Histories

### Presentation

On day 2, the patient developed erythema on the anterior chest. Throughout that day, the erythematous rash became purpuric. Only skin exposed to the phototherapy lights was affected (Figure 1).

Figure 1.
Well-demarcated, confluent macular purpura on the cheeks, chest, abdomen, anterior arms, and anterior legs. Purpura spares areas covered by monitor leads and wires.

### Vital Signs (Day 2)


This chapter discusses the role and impact of personality on the vote. It reopens the question of what a notion of 'personality' entails, focusing on eight discrete personality traits: sensitivity, anxiety, alienation, freedom aspiration, extraversion, risk aversion, care, and confrontation. The chapter assess whether personality derivatives such as favourite colours and animal resemblances also help to explain differences in electoral behaviour. It then introduces a twist to the question of morality. While different people may be more, or less, vocal about their sense of morals, the most relevant variation in electoral politics pertains rather to moral hierarchization: different citizens prioritizing differently some moral principles over others. The chapter also reintroduces the notion of egocentrism and sociotropism in the vote. It identifies four dimensions of sociotropism: economic, social, safety, and misery.


The Control, Astrophysics and Structures Experiment in Space (CASES) will investigate critical control technology applicable to sthbilizing and pointing large flexible structures in space. This shuttle-based experiment will provide active control ofa 32 m extendibleboom structure usinggas thrusters for pointing and angular momentum exchange devices (AMED) for active damping to suppress vibrations. In conjunction with this controls-structures interaction experiment, an x-ray diffraction instrument will investigate high energy sources at the center of the galaxy and on the surface ofthe Sun. An occulter plate on the tip ofthe boom and proportional counters at the base of the boom comprise an x-ray telescope with a 32 m length. High spatial resolution depends on accurate knowledge and, to alesser extent, control ofthe position ofthe boom tip assembly relative to the proportional counters located at the base ofthe boom. The Remote Attitude Measurement Sensor (RAMS) was designed to provide high accuracy and update rates while measuring numerous reflective targets on a flexible structure. RAMS is presently baselined to fill two important sensor needs for CASES. First, as a tip displacement sensor, RAMS willprovide accurate knowledge ofthe position and orientation of the boom tip assembly. Second, as a boom motion tracker, RAMS will monitor 43 reflective targets that are distributed along the length ofthe boom and provide displacement (eigenvector) information for post-facto processing. This paper describes the design and operation of RAMS as both a tip displacement sensor and a boom motion tracker. It explains how RAMS interfaces with the CASES closed-loop control system and how systems identification is accommodated.


CLS (Collecte Localisation Satellite) was contracted by ESA (European Space Agency) to develop the ocean geophysical reference processor of the ENVISAT radar altimeter. After briefly describing the different main processes, this paper presents the validation of this reference processor with real data from the TOPEX/Poseidon mission.


Historians of technology and archaeologists share an interest in understanding technological change. Members of both disciplines fashion contextualized narratives about the invention, commercialization, and adoption of specific technologies and also put forward generalizations—models and theories—that apply to many technologies in many societies. Although there are no sure formulas for crafting generalizations, I have found it helpful to partition a given process, such as invention, into several classes or behavioral contexts, each of which might exhibit a specific pattern of activities. For example, in a recent study I elaborated Thomas Hughes's construct of "reverse salients" and from it generalized the "cascade model" of invention.1 This model identifies "complex technological systems" as a behavioral context of inventive activities. The key premise is that during the development and deployment of a complex technological system, emergent


Herding behavior is one of the investor's irrational behavior that can destabilize the stock market. When herding happened, investors tend not to use the analysis in making investment decisions but follow the market consensus or imitate a decision of other investors. This study discusses whether herding behavior occurs in emerging market specifically Indonesia Stock Market and also developed market specifically Singapore Stock Market. By looking at the relationship between return market portfolio and Cross Sectional Absolute Deviation (CSAD), then herding behavior in a market can be identified. Herding detection performed on different market conditions, so this study using quantile regression analysis. The result of this study shows that there is no indication of herding behavior in both stock market, which means that investors tend to behave rationally in making investment decisions.


A Fission Track Analysis (FTA) method for assessing =%I in urine samples was first developed at Brookhaven National Laboratory (BNL) in 1988; it then had a detection limit of 100 aCi (3.7 pBq). Since that time, several steps were introduced that increased chemical recovery and lowered the detection limit to less than 10 aCi per sample. These improvements include a process of micro-column separation of plutonium in the final stages (patent application in process). The improved FTA method was applied to 22 urine samples fiom male staff at BNL. The results showed that fiom fallout excreted in urine was 33 & 11 aCi (1.2 pBq) per day.


The present invention relates to a gear cutting machine, end milling cutters and shaping methods. This is performed by gear cutting machine having at least one molding milling toolholder for mounting at least one workpiece of an end mill cutting teeth, especially for gear cutting toothed wheel, wherein the tool holder or an end mill and / or a workpiece holder adjustable, and the axis of the end mill may be arranged approximately parallel to the surface of the processing teeth clamping the workpiece, and wherein the tool axis may be applied to the tooth surface profile, and an end mill having an outer contour corresponding to the contour of the tooth surface.


Introduction Carfilzomib (CFZ) is a selective proteasome inhibitor approved in the US for the treatment of relapsed and refractory multiple myeloma (MM) (Kyprolis PI, 2012). The approved dose and schedule for single-agent CFZ is 20/27 mg/m2 administered intravenously (IV) over 2–10 minutes on days 1, 2, 8, 9, 15, and 16 of a 28-day cycle. Using the same consecutive daily dosing schedule, 56 mg/m2 CFZ administered IV over 30 minutes has been found to be well tolerated as a single agent or in combination with dexamethasone (DEX), with an overall response rate (ORR) of 55%–60% for patients (pts) with relapsed and refractory MM (Badros et al, ASH 2012, abstract 4036). In this multicenter single-arm phase 1/2 study (CHAMPION-1; [NCT01677858][1]), we are evaluating the safety and efficacy of once-weekly CFZ with DEX. Results from the phase 1 dose-escalation portion of the study are presented herein, including an evaluation of safety, pharmacokinetics (PKs), clinical benefit rate (CBR, ≥minimal response [MR]), ORR (≥partial response [PR]), and time to response.

Methods Pts with relapsed or refractory MM who had received 1−3 prior regimens were eligible for enrollment. Pts were treated with CFZ as a 30-minute IV infusion on days 1, 8, and 15 of each 28-day cycle in a standard 3+3 dose-escalation scheme. All pts received CFZ (20 mg/m2) on day 1 of cycle 1; subsequent doses started at 45 mg/m2 in the first cohort and were escalated to 56, 70, or 88 mg/m2in successive cohorts until the maximum tolerated dose (MTD) was determined. Pts also received 40 mg DEX (IV or oral administration) on days 1, 8, 15, and 22 of cycles 1–8. During cycle 9 and beyond, patients continued to receive the same doses and schedules of CFZ and DEX, with the exception that DEX was not administered on day 22. The primary objective of the phase 1 portion of the study was to determine the MTD of weekly CFZ plus DEX. Response was assessed by IMWG criteria. MR was assessed by EBMT criteria.

Results As of July 11, 2013, 18 pts have been enrolled, with a median age of 63 years (range, 43–84), and a median of 1 prior regimen (range, 1–2). The 45 and 56 mg/m2 dosing cohorts enrolled 3 pts each, and the 70 and 88 mg/m2 dosing cohorts enrolled 6 pts each. Pts have received a median of 5.5 cycles of treatment. At 88 mg/m2, 2 dose-limiting toxicities (DLTs) were observed: grade [Gr] 3 dyspnea and Gr 3 vomiting. All 18 pts were evaluable for safety. The only grade 3 adverse event (AE) reported in more than 1 patient was increased blood creatinine (n=2). Four serious AEs were reported in 3 pts: Gr 3 dyspnea, Gr 3 pneumonia, Gr 3 increased blood creatinine, and Gr 4 hyponatremia. No peripheral neuropathy was reported. Six pts discontinued treatment for the following reasons: AEs of decreased renal function (n=1) and dyspnea (n=1), progressive disease (n=2), physician decision (n=1), and withdrawal of consent (n=1). Five patients had a dose reduction from 88 mg/m2 to 70 mg/m2 (1 due to an AE, 1 due to a DLT, and 3 per protocol due to the 2 DLTs in the 88 mg/kg2 cohort); 2 of the 5 pts had an additional dose reduction owing to AEs. PK analysis (n=12) from pts that received 20, 70, or 88 mg/m2 of CFZ showed a dose-dependent increase in mean Cmax (703, 2640, and 3172 ng/mL, respectively) and AUC (283, 1045, and 1247 h·ng/mL, respectively) for CFZ. The mean terminal half-life was ∼0.8 h. Fifteen pts were included in the response evaluation; 3 pts did not have a postbaseline assessment at the time of the data cutoff. The ORR was 67%, and the CBR was 87% (4 pts achieved a complete response, 1 very good PR, 5 PR, and 3 MR). One pt had stable disease, and 1 pt was not evaluable for response, as the pt had a DLT and was no longer on treatment. Median time to response for pts that achieved a ≥PR (n=10) was 1.6 months.

Conclusions These preliminary results demonstrate that weekly CFZ at doses ≥45 mg/m2 in combination with DEX in pts with relapsed or refractory MM was tolerated and showed rapid and promising efficacy with an ORR of 67% and a CBR of 87%. Weekly infusion of 70 mg/m2 CFZ demonstrated a lower Cmax, comparable half-life, and higher AUC per cycle compared with the currently approved twice-weekly CFZ dosing regimen. Overall, these findings suggest that CFZ at doses up to 70 mg/m2 in combination with DEX may be administered in a convenient once-weekly schedule. The study is ongoing to confirm the MTD at 70 mg/m2, at which point the phase 2 portion of the study will be initiated.

Disclosures: Berenson: Onyx: Consultancy, Honoraria, Research Funding. Off Label Use: Carfilzomib is a selective proteasome inhibitor that is approved in the US for the treatment of relapsed and refractory multiple myeloma. Klein: USONC: Employment. Rifkin: Onyx: Membership on an entity's Board of Directors or advisory committees; Celgene: Membership on an entity's Board of Directors or advisory committees; Millennium: The Takeda Oncology Company: Membership on an entity's Board of Directors or advisory committees. Patel: Onyx: Employment, Equity Ownership. Dixon: Onyx: Employment, Equity Ownership. Ou: Onyx: Employment, Equity Ownership.

 [1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT01677858&atom=%2Fbloodjournal%2F122%2F21%2F1934.atom


This paper studies the convertible bond with risk in jump-diffusion model.Under the hypothesis that the stock price is satisfied to geometic Brown motion,the pricing formulas of the convertible bond are obtained by means of Martingale approach(risk-neutral valuation).


A lean visual dashboard was designed based on the management theory of lean production dashboard(LPD).The parameter index system of the visual dashboard was established on the basis of analyzing the content and selection principle of the dashboard's parameter index.Combined with the workstation information model and the real-time data acquisition of parameter index system of the dashboard,a calculation model of LPD parameter index was developed through studying the processes from collecting data to displaying parameter.The method was applied to the assembly production of toy robots.Results show that the parameter index system of LPD is reasonable and the calculation model is feasible.


Magnesium (Mg) batteries have attracted significant interest as low-cost batteries with high electromotive force, capacity, and safety. This is partly attributed to the superior property of Mg in having two valence electrons and the lowest standard electrode potential (ca. −2.36 V vs. SHE) among the air-stable metals[1]. There is another advantage that Mg metal can be used as a negative electrode material with significantly high capacity (ca. 2200 mAh g, 3830 mAh cm) since a Mg deposit does not tend to form dendrites. Furthermore, Mg resources are abundant and widely spread in the world. One path to the realization of Mg batteries with such excellent properties was trailblazed by Aurbach et al., who reported a series of detailed studies of reversible Mg deposition and dissolution in ethereal electrolytes based on the Grignard reagents (RMgX, where R: alkyl or aryl group, X: halogen) in addition to some Chevrel compounds as positive electrode active materials. However, there still remain many issues to be solved for the realization of commercial Mg rechargeable batteries. For example, it is necessary to develop electrolytes with a wider potential window (electrochemically-stable potential region), rechargeable positive electrode active materials with higher redox potentials and chargedischarge rates, and low-cost current collectors. We have investigated the current collectors stable at high potentials for the evaluation and discovery of novel positive electrode active materials working in Grignard reagent-based electrolytes. The presence of corrosive halide anions in Grignard reagent-based electrolytes causes the pitting corrosion of affordable metals such as Al, Cu, Ni, Ti, and stainless steel. In contrast, noble metals, glassy carbon, and Nb are stable in the Grignard reagent-based electrolytes. Figure 1 shows cyclic voltammograms measured in the potential range from −1.0 to 4.0 V vs. Mg using the stable working electrodes. The current density for electrolyte oxidative decomposition is different with the kind of electrode, and is the lowest on Nb, resulting in wider potential window of the electrolyte about 3.5 V vs. Mg. Furthermore, the shape of the voltammogram does not change during 10 cycles except for the slight increase in the anodic current density above 3.5 V vs. Mg. Figure 2 shows surface SEM images of Nb after cyclic voltammetry in the potential range from −1.0 to 4.0 or 5.0 V vs. Mg. Both corrosion pittings and deposits are not observed on the Nb surface after the cyclic voltammetry in the potential range from −1.0 to 4.0 V. After the voltammetry in the potential range from −1.0 to 5.0 V, a complicated structure composed of carbon is observed; this could be the product of the electrolyte oxidative decomposition. Thus, it can be concluded that the widening of the potential window on Nb is attributed to a kinetic effect, i.e. lower catalytic activity of Nb for the electrolyte oxidative decomposition compared with those of Pt and glassy carbon. Some evaluation examples of positive electrode active materials for Mg batteries will also be presented and its perspective will be discussed in light of our recent development of the stable current collectors.


The article starts with the significance of popularized researches into Marxism in contemporary China and makes a more thorough and comprehensive exposition of the connotation features of the popularizing,disseminating and spreading of Marxism in modern China and then puts forward some points of view and proposals.


Jupiter's Great Red Spot (GRS) is one of its most distinct and enduring features. Since the advent of modern telescopes, keen observers have noted its appearance and documented a change in shape from very oblong to oval, confirmed in measurements from spacecraft data. It currently spans the smallest latitude and longitude size ever recorded. Here we show that this change has been accompanied by an increase in cloud/haze reflectance as sensed in methane gas absorption bands, increased absorption at wavelengths shorter than 500 nm, and increased spectral slope between 500 and 630 nm. These changes occurred between 2012 and 2014, without a significant change in internal tangential wind speeds; the decreased size results in a 3.2 day horizontal cloud circulation period, shorter than previously observed. As the GRS has narrowed in latitude, it interacts less with the jets flanking its north and south edges, perhaps allowing for less cloud mixing and longer UV irradiation of cloud and aerosol particles. Given its long life and observational record, we expect that future modeling of the GRS's changes, in concert with laboratory flow experiments, will drive our understanding of vortex evolution and stability in a confined flow field crucial for comparison with other planetary atmospheres.


Yao and Kummer(1)(2) reported that Na+ ion in a β-alumina single crystal can be exchanged in molten salts with a number of monovalent ions as Ag+, Li+, K+, Rb+, Cs+, Tl+ and NH+4 and divalent ions as Pb2+, Fe2+, Zn2+, Mn2+, Sr2+ and Ba2+. They also determined the self diffusion coefficients of Na+, Ag+, Li+ and Rb+ ions in the β-alumina single crystal. After their report, many studies have been presented concerning the structures, mechanisms of the ionic conduction and ionic conductivities of the ion-exchanged β-alumina. Besides the ions mentioned above, the following ions were found to be exchanged with Na+ ion in the βalumina: NO+(3), H3O+(4), Ga+(5), Cu+(6), In+(7), etc. Farrington et al.(8)(12) found that Na+ ion in a β"-alumina Single crystal can be completely exchanged with divalent ions as Ca2+, Sr2+, Ba2+, Mn2+, Zn2+, Cd2+, Hg2+ and Pb2+. They measured the ionic conductivities of some of the beta-alumina. The Pb2+ -β"-alumina has been found to show the highest ionic conductivity(8) in all the β"-aluminas ion-exchanged with divalent ions. Recently, Dunn and Farrington(13) found that Na+ ion in the β"alumina single crystal can be exchanged completely or partially with Gd3+, Nd3+, Eu3+, Yb3+, Sm3+, Tb3+, Dy3+, Bi3+ and Pr3+ ions. At the present stage, much attention is paid to the physical and chemical properties and the structures of the ion-exchanged beta-alumina


The aim of this paper is to identify the complexity of why it is hard to achieve business/IT alignment. This is investigated from the social dimension at a Swedish telecom company. The study has a qualitative approach and the data is collected by conducting 16 interviews and 4 observations. The analysis of the field data is done by using a practice lens of institutional logics. This framework is used to understand the complex interplay among social actors working at the company's IT and business department. The purpose is first to understand how respective department act and how their relationship unfolds in practice. Secondly, it is to understand the implications on business/IT alignment. The study presents three main findings which adds institutional complexity when aiming for alignment; different pace in an external and internal world, the importance of materialization practices, and the consequences of implementing a new management practice. Those findings explain the institutional complexity when aiming for alignment and why social difficulties arise. Furthermore, those findings identify benefits from friction and highlight the consequences of segmenting, hybridizing and black-boxing social domains and practice repertoires. Altogether, this paper provides new insights into the challenges of achieving business/IT alignment, while it also highlights the importance of embracing institutional complexity rather than trying to resolve it.


State sovereignty in international law is not a solution, in the international world as a legal entity that acts as a subject of international law. This also happens between one country or another, which can then be announced the deeds agreed to by each country are not appropriate, because they must be approved by the deeds of other countries or we can call it the Relativity of State.There are three thoughts in understanding the concept of state sovereignty over developing air space. The first is that air space cannot be used or used by anyone because in principle, the state does not have sovereignty. Secondly, special rights such as freedom of air that do not limit the height of the airspace boundary are obtained by the State of the Netherlands. And finally, the principle that the state has freedom of airspace, but there is a territory or territorial zone that gives certain rights to the under the state that can be implemented. This research has the purpose of being able to know and analyze how the regulation and accountability of the state in an effort to protect and maintain the country's sovereignty over air space viewed from the perspective of international law. The research method used in this study is the normative juridical library method, where this normative juridical research is a study using literature with primary data such as laws and regulations, the scientific work of scholars, as well as from several books. Then it will be explained or described in a deductive description supported by literature study. Based on the results of research and discussion, we can find out that the thinking on the concept of state sovereignty territory starts from the three theoretical ideas mentioned earlier. Then put together in international agreements as stated in the 1944 Chicago International Civil Aviation Convention especially the definition of state sovereignty over air space, paragraph 1 which reads "the contracting states recognize that every state has complication and exclusive sovereignty over the airspace above its territory". The state is fully responsible for the maintenance and protection of the country's sovereign territory over air space.


On September 17, 2006 serious damage had been caused by tornado accompanying Typhoon Shanshan (T0613) at Nobeoka City, Miyazaki Prefecture. Due to the gust the first and the second cars of a limited express train cars were overturned. More than a thousand houses were damaged. Three people were killed. The notable feature of this wind damage was impact of wind borne debris. The estimated damage scale was F2 and the maximum gust speed of 46m/s was observed at a factory yard. The area of damage footprint was spread to 7.5 km from Pacific coast to the north-east by 100m to 200m in width. Results of the site investigations were reported.


A for esterification CATALYTIC O noncatalytic ACID PROCESS OR anhydrides with a mono-ALCOHOL OR A COMPOUND polyhydroxy COMNPRENDE the steps of adding reagents to the reaction vessel to form a mixture of reaction and heat the reaction mixture and HOLD PRESSURE SUFFICIENT FOR THE bOILING MIXTURE OF rEACTION SO THAT OCCURS esterification AND ELIMINATE WATER AS STEAM WHILE MIXING rEACTION CONTINUES TO CONTINUOUSLY MIXING IN THE REACTOR vessel so that at least about 2.5 A 20 VOLUMES rEACTION MIXTURE OF INTERNALLY BE recirculated PER MINUTE, SO IS STEPPING FCR.


Additive manufacturing technologies are becoming more and more important for the implementation of efficient process chains. Due to the possibility of a near net shape, manufacturing time for finish-machining can significantly be reduced. Especially for conventionally hard to machine materials like gamma titanium aluminides (γ-TiAl), this manufacturing process is very attractive. Nevertheless, for most applications, a rework of these generative components is necessary. Independently of the mechanical material properties, electrochemical machining is one promising technology of machining these materials. Major advantages of electrochemical machining are its process-specific characteristics of high material removal rates in combination with almost no tool wear. But electrochemical machining results are highly dependent on the microstructure of the material regarding the surface roughness. Therefore, this article deals with research on electrochemical machining of electron beam melted γ-TiAl TNB-V5 compared to a casted form of this alloy. The difference between the specific removal rates as a function of current density is investigated using electrolytes based on sodium nitrate and sodium chloride. Moreover, the dissolving behavior of the electron beam melted and casted structure is analyzed by potentiostatic polarization curves. The surface roughness is heavily dependent on a homogeneous dissolution behavior of the microstructure. Thus, the mean roughness as a function of current density is investigated as well as rim zone analyses of the different structures.