Abstract Analysis investigating subject content and trends in engineering management literature from 1993 to 2000 is reported. 479 articles from Engineering Management Journal and IEEE Transactions in Engineering Management were analyzed using content analysis of article subject classifications. Results indicate a consistent effort by engineering management researchers to apply technical skills in the larger context of answering the leadership and management questions facing technical organizations today. The preponderance of engineering management research in the manufacturing and services industry sectors was confirmed. These trends were identified: decreasing research attention in the subject of strategic planning; increasing research attention in the services industrial sector; and increase in the subject of innovation. Varying emphasis on the subject of total quality/quality assurance was seen throughout the time period of this research.


Case Description- A 2-years-old female Iranian cross-breed goat with a history of chronic anorexia and intermittent regurgitation after eating food or drinking water was referred to the Veterinary Clinic.
Clinical Findings- In clinical examination, persistent fever, swelling of distal portion of the neck, clinical evidence of laryngeal and pharyngeal dysfunction was detected.
Treatment and Outcome- A fiberoptic endoscopic examination and positive-contrast radiography revealed megaesophagus. The animal was not treated because of postoperative complications.
Clinical Relevance- Megaesophagus is a dilatation and atony of the body of the esophagus which occurs sporadically in animals and rarely in ruminants.


Analysis of Health Diagnostic Instrument of Evaluation Program in Training Institute" has participants of 19 heads (Echelon II, III, IV) and 148 staff. The study applies a descriptive study method with a quantitative approach. Forming an evaluation program health instrument in the training institute goes through four stages: previous research studies, test construction, validity tests, and reliability tests. The data collection technique used a questionnaire that was later converted into a Google Form link. The result has proven that the instrument substantiates the measuring tool used to diagnose the health of the evaluation program in the training institute. The instrument of usability testing illustrates that the health evaluation program at the Center for Teacher and Staff Development Science falls under the "Healthy" category, scoring 84.93 as the lowest. Meanwhile, kindergarten and the special center of teacher and staff development scored 88 as the highest, followed by the center of teacher and staff development scoring 86.04. The scores indicate that they are both in the "very healthy" category. The study advances the idea that the three institutes have implemented the evaluation program activities according to the research dimensions: the preparation stage, implementation stage, and reporting stage


The theory of justice in Dante can be analyzed from the cultural heritage perspective of the Romanitas; nevertheless, the dialectic between the imperial Rome and the Christian Rome is resolved in asymptotic terms, because the perfect unification of the two cities only could be achieved in a dimension of immortality. On the contrary, attempts to superimpose the two Roms on the earthly world Rocco T 19_Maquetación 1 16/01/2019 23:08 Página 55


Leaf symptoms of rizomania in sugar beets appear in various types, such as yellow vein, yellowing, crinkling and magnesium or potassium deficiency-like symptoms. On the other hand, proliferation of rootlets and necrosis of vascular bundles are the general symptoms in roots1). Infection of Polymyxa betae Keskin, a fungus that is an obligate parasite, is consistently observed in the rootlets of sugar beets affected by rizomania2). A rod-shaped virus, beet necrotic yellow vein virus (BNYVV), has also been isolated from leaves showing necrotic yellow vein symptoms, and from rootlets of the rizomania-affected plants3,4). The authors already reported that symptoms specific to rizomania were produced by inoculation with the virus alone5). Kanzawa reported that the number of resting-spore clusters of P. betae in the infested nursery soil had an influence on the degree of rizomania incidence and its damage to sugar beets6). Rod-shaped virus particles were reported to be observed in the zoospores in zoosporangia of P. betae, and this suggested that P. betae would be a possible vector of BNYVV7). This paper deals with further evidence on the transmission of BNYVV by the resting-spores of P. betae. Twenty-day-old sugar beet seedlings (Beta vulgaris L.c.v. Monohope) grown in sterilized soil were used. Removing the soil from the roots by washing, the seedlings were inoculated with P. betae by addition of 0.1ml of distilled water containing the resting-spore clusters in various concentrations to their roots. Then each seedling was transplanted into a pot (21cm in diameter) containing sterilized soil, and grown in a greenhouse for three months. The purification procedure of resting-spore clusters of P. betae is shown in Fig. 1. Rootlets with the resting-spore clusters (Fig. 2) were collected from sugar beet plants affected by rizomania. They were chopped in distilled water, and then filtered succesively through 100-and 400-mesh screen. The filtrate was centrifuged at 1,000rpm for three minutes. The pellet was suspended in distilled water, and then resting-spore clusters were collected by the use of a micromanipulator. The collection procedure was repeated several times. The final suspension of the resting-spore clusters was almost pure except for the contamination of only a few bacteria (Fig. 3). The resultant solution


A Sagnac interferometer monolithically integrated with parallel-amplifier structure (SIPAS) is described. Filter-free wavelength conversion and full bit-rate conversion from 10-Gb/s random WDM channels to a 40-Gb/s channel were demonstrated.


Use of the material by several of the subjects did not reveal positive results for the 3 weeks that they were used on a daily basis. It is interesting that the occlusive patch was capable of eliciting the reaction but nonocclusive patch and nonocclusive usage failed to elicit the response. Abitol is a colorless, tacky balsamic resin. It is a high moleculate primary monohydric alcohol derived from rosin acids but had been hydrogenated to reduce unsaturation. It has a high refractive index, excellent color, low odor, good adhesion and resistance to oxidation. Typically, Abitol has found wide application with natural rubber, synthetic rubber, nitrocellulose, and other polymers as a plasticizer and tackifier for emulsion, solvents, and hot-melt adhesives. Toxicological data over the years have shown it to be rather safe. It was tested many years ago by a modified Schwartz technique and showed little irritation. It was interpreted as a nonsensitizer from data at that time, 28 years ago. It is felt that this chemical should be sparingly utilized in cosmetic preparations, owing to the nature of these positive reactions. Experience with this chemical in cosmetics used properly has shown limited problems.


abstract: transition rate models are very appropriate for the analysis of social processes as demonstrated by the work of coleman , hannan, tuma and other authors. in recent years these models became increasingly popular in empirical social research concerned with time related data. in particular, there is a great need for techniques which are able to deal with the problem of observed and unobserved heterogeneity. in this paper some characteristics of a model with unobserved heterogeneity are analyzed. it is assumed that the hazard rate depends on a gamma distributed error term. the model is applied to recidivism and unemployment data and compared with alternative hazard rate models. estimation of parameters is performed with tuma's programrate. important implications of the model are derived which allow clear and unambigious interpretations of estimated parameters.;


The objective of this study is to evaluate pediatric patients using existing macrophage activation syndrome (MAS) and hemophagocytic lymphohistiocytosis (HLH) scoring systems to determine how these systems identify patients with cytokine storm syndrome (CSS) in the setting of a multisystem inflammatory syndrome in children (MIS‐C) and active coronavirus disease 2019 (COVID‐19) infection.


This paper describes the FPGA implementation of a 3GPP compliant TCC (turbo convolutional codes) codec. The decoder employs the MAP algorithm, utilizing the max* operator, and achieves a BER of 10/sup -6/ for a 1.5 dB SNR. In addition to providing an overview of the datapath architecture, the C based design and verification methodology is presented.


This article seeks to promote what might be called a traditional form of ethnography. It recognises that all traditions change, but puts forward a view that, for an activity or product to be regarded as ethnographic, there is a need for some recognisable continuity with what has been regarded as ethnography in the last century. This article thus presents a defence of rigour and systematic research within ethnography. It is not a response to the other papers within this special issue, but it does put forward a case for a particular form of ethnographic research and representation that follows rigorous research methods and presents the findings of that research in a systematic and clear way. The first section of the article discusses the nature of ethnography that I wish to promote. The second provides a critique of some specific cases where the authors wish to apply the term ethnography, focussing on autoethnography and performance ethnography. The conclusion suggests ways in which these newer forms of qualitative inquiry might be made more rigorous and thus warrant the name ethnography as it has been traditionally understood.


By understanding how social network sites work, researchers can better assess their effects on different kinds of social interactions as well as the associated benefits and risks. The Web extra at http://youtu.be/_Dz9FR1Bf-U is a video interview with column editor John Riedl, who discusses the topics and writing styles that work best if you're interested in writing for the Social Computing column.


The attorney–client privilege is a legal protection that prevents the disclosure of confidential communications made between an attorney and client for the purposes of legal advice or assistance. Based on the attorney's duty to protect a client's confidences, the attorney–client privilege is one of the oldest privileges recognized by American courts and requires the existence of an attorney, a client, a communication made for the purpose of obtaining legal advice or assistance, and an anticipated confidentiality. With few exceptions, the attorney–client privilege serves as an absolute protection unless the litigant waives the privilege through disclosure of the confidential communications.

Keywords:

attorney;
confidentiality;
ethics;
evidence;
privilege


The sustainable transition to a net-zero economy may require large quantities of low-cost clean hydrogen. In a fully renewable energy system, coproduction of electricity and green hydrogen may provide synergies (such as flexible demand, reduced renewables curtailment). On the other hand, separating electricity and hydrogen production could offer advantages (such as better renewable resources and less onerous power quality requirements for power electronics). We quantify the potential synergies of "integrated" electricity and hydrogen production versus stand-alone ("islanded") production of hydrogen in systems entirely powered by wind and solar. We explore the trade-offs for several countries, including Germany, Spain, Chile, Australia and the United Kingdom, in a simple six-node model that enhances analytical understanding. Our findings show that integrated hydrogen production is the lowest cost solution when hydrogen demand is low (less than 20% of final energy). At high shares of hydrogen demand (80% of final energy), islanding electrolysers can result in system cost reductions of up to 9%. These results are especially relevant for countries that export hydrogen, as it suggests that they should deploy electrolysers primarily in islanded settings.


Purpose – The purpose of this paper is to present work on the incorporation of capacitors into printed circuit boards (PCB) as a method to measure moisture content and follow moisture diffusion under ground planes.Design/methodology/approach – PCBs were manufactured of FR‐4 incorporating different arrangements and sizes of capacitors formed between the tracks on adjacent layers of the PCB. The boards were placed in an 85°C and 85 per cent relative humidity (RH) environment to absorb moisture before baking at temperatures of 80, 110 or 125°C with the capacitance periodically measured. The effect of ground planes with different densities of plated and non‐plated through holes (PTH) has been studied by placing capacitors between ground planes.Findings – Parallel plate capacitors embedded within a PCB showed a 10 per cent capacitance increase going from a dry state to being saturated with moisture in an 85°C and 85 per cent RH environment. The slow ingression of moisture under the capacitance planes meant tha...


Hilton, J. R. and Thomas, J. A. 1987. Changes in respiratory potential of dormant and non-dormant Galium aparine L. (cleavers) seeds during dry storage.—J. exp. Bot. 38: 1484-1490. Pre-germinative rates of 02 uptake of two collections of Galium aparine L. seed were compared throughout a 9 month period of dry storage at 4°C, 23 °C and at ambient (frost-protected) temperatures. Uptake of O2 by the dormant seeds was generally higher than that of the less dormant seeds except when freshly-harvested. Moreover, changes in the 02 consumption of seeds stored at ambient temperatures could be associated with periods of germination and seedling emergence in the field. The results are discussed in relation to changes in respiratory metabolism during dormancy breakage.


In this study, we conducted text analysis to clarify the " feelings and considerations about the community (thoughts on the community) " of aged individuals in depopulated rural districts with low birth and high death rates, to identify a basis for public health nurse activities that contribute to improved functioning of aged individuals in rural areas. Quantitative text analysis was performed on free descriptive data collected from 362 aged individuals in rural districts; a co-occurrence network was created and correspondence analysis was performed. Six categories were extracted by analyzing the structure of the co-occurrence network: " loneliness because of the increasing number of unoccupied houses with few children and young people around " , " changes in the neighborhood and relationship with neighbors over time " , " continuous aging and depopulation of the village " , " preciousness of living with and spending time with family " , " maintaining good health and healthy aging " , and " difficulties and worries about inconvenient access to hospitals, public administrative offices, and shops " . Correspondence analysis of extracted words identified " inside the


Cathepsin K is a cysteine protease well known for its importance in bone remodeling and inhibitors of cathepsin K are currently in clinical trials for osteoporosis treatment. However, severe side effects were induced by cathepsin K inhibitor treatment of rats or mice affecting both, peripheral organs and the central nervous system (CNS). This is due to the fact that cathepsin K has also been detected in brain parenchyma only recently. Lately, we have shown that cathepsin K deficiency in mice induces structural and functional alterations in the CNS which are associated with learning and memory deficits. Furthermore, the proteolytic network was deregulated in the brain of cathepsin K-deficient (Ctsk-/-) animals. Moreover, astroglia-rich primary cell cultures from Ctsk-/- mice revealed an increase in enzymes of the glutathione metabolism, as well as elevated numbers of oligodendrocytes compared to wild type controls. Thus, we propose that cathepsin K contributes significantly to cellular and molecular homeostasis of the CNS. Cathepsin K was also demonstrated to bear a vital function in the thyroid gland, because it contributes to thyroid hormone (TH) liberation. THs are well known to be crucial for proper CNS development and its maintenance during adulthood. Therefore, we hypothesized that brain and thyroid functions of cathepsin K might be linked. However, our results suggest that Ctsk-/- mice do not suffer from classical hypothyroidism. Interestingly, trace amine-associated receptor 1 as well as TH transporters were found to be deregulated in the CNS of Ctsk-/- mice. Since all markers of classical thyroid regulation were comparable in wild type and Ctsk-/- mice, but markers of non-classical thyroid regulation differed significantly, we believe to have identified an animal model suited to study non-classical TH actions on the CNS in addition to serving as a mouse model for studying the general functions of cathepsin K in the CNS.


Cytogenetic relationships among three races of pocket gophers ( Geomys bursarius complex) at two hybrid zones in eastern Texas were examined by use of chromosome-banding and meiotic analyses. Race E (2n = 74, FN = 72) interacts with races F (2n = 70, FN = 74) and G (2n = 70, FN = 72) at a narrow (0.8 km) hybrid zone in Burleson Co., Texas. Of 78 pocket gophers collected there, three (3.8%) were F1 hybrids and none was a backcross or F2 hybrid. Races F and G contacted one another at a second hybrid zone 35 km in width, located in Milam and Burleson counties, Texas. Backcross and F2 hybrids between races F and G could not be distinguished chromosomally from F1 hybrids, but distribution patterns of parental and hybrid pocket gophers suggest that hybrids included backcross or F2 animals. G-band chromosome analysis revealed that races F and G differ from race E by at least two centric fission-fusion events. Further chromosomal rearrangements distinguishing race E from the other two races were indicated by G-bands, but could not be identified specifically. C-banded karyotypes revealed heterochromatic differences between race E and races F and G. Races F and G differed in one whole-arm heterochromatic change, as evidenced by C-banding, and by a paracentric inversion, demonstrated by G-banding. Chromosomal distinctions among the races were supported by meiotic analyses of hybrids. Degree of hybridization among the three races and the width of the hybrid zones reflect the extent of cytogenetic divergence of the races. The narrow zone between the 2n = 74 form and the 2n = 70 forms is most likely the result of meiotic imbalances and associated decreases in viability from a minimum of two and probably more rearrangements. The broad zone of hybridization between the two 2n = 70 forms is characterized by much higher hybrid production. The identified rearrangements in the karyotypes of races F and G and their hybrids have not resulted in the degree of reduced fitness evident in hybrids involving race E. Races F and G, and race E interact as species, recognized as Geomys attwateri and G. breviceps , respectively.


This paper presents a method for the design of nonconservative low-order controllers achieving robust performance in the case of multi-input single-output parallel structure plants subject to unstructured uncertainty. The first step is the analytical generation of gain-phase controller bounds, as in quantitative feedback theory (QFT). Then, to avoid the difficult step of QFT loop shaping, which often produces high-order controllers, these bounds are translated into the controller parameter space where the iterative design of low fixed order controllers takes place. This, as well as the design transparency offered by this technique, constitutes appreciable advantages over the other popular robust performance design method of /spl mu/-synthesis. Other important features are the fact that no extra conservatism is introduced by the method presented and the fact that the method is directly compatible with a sequential loop closing strategy. Finally, the direct search optimization of any additional secondary criteria is possible.


Post-industrial cities often find themselves at a crossroads as to whether to find a new identity or embrace their industrial past. In late 2017, after the closure of major manufacturing plants in the region, the Australian city of Geelong was designated a UNESCO City of Design and embraced a "Clever and Creative" strategy which acknowledged Geelong's industrial and design past in responding to contemporary technological, demographic, and economic challenges. However, questions remain as to which versions of the past are valued by the local community and how these stories can be shared. To better understand the social value of design and manufacturing heritage in Geelong as well as to get initial feedback on how to interpret this type of heritage through novel immersive extended reality (XR) experiences, the researchers took a community-led approach. This paper reports on the results of the initial online community surveys (N = 55–137) and in-person stakeholder interviews (N = 5) with carefully selected representatives of the local government, education, heritage, tourism, and engineering sectors. The study's outcome demonstrates the importance of design and manufacturing heritage for the local community's identity. Moreover, this type of heritage provides a source of inspiration, learning opportunities for future creative problem-solvers, and economic opportunities through tourism. By engaging with the social value of design and manufacturing heritage, this paper argues that more effective and targeted storytelling, game-like applications, and other digital immersive experiences such as extended reality (XR) can be used to better engage with audiences.


The interaction of an imploding plasma–vacuum boundary (PVB) with a collisionless Z pinch for the case where the ions have orbits comparable to the radius is studied. Two principal results are found. First, the development of sheared axial ion flow occurs as a result of large Larmor radius (LLR) ions interacting with the moving PVB. This contrasts strongly with the equivalent case in ideal magnetohydrodynamics (MHD). The second result is a modification to current density profiles. These are smoother (due to LLR effects) than those from ideal MHD.


Evaluating the performance of nonprofit organizations has been of growing importance for the last several decades. Although there is much good that can come out of self-improvement, there is substantial heterogeneity within the sector that calls into question the usefulness of ''across the board'' evaluation tools. In this article, the authors assess nonprofit evaluation practices, at both the organizational and the programmatic levels. Through a multitheoretical framework, the authors explore the extent to which the adoption and uses of evaluation reflect strategic alignment with heterogeneous nonprofit roles or the institutionalization of the organizational environment. The authors find evidence that institutional perceptions are consistent predictors of whether nonprofit organizations adopt particular practices. Diverse roles are not consistently associated with the adoption of particular practices, but the uses of evaluation are diverse and specific to nonprofit organizations' unique strategies and roles.


THE state of 'steady growth' without inflation or unemployment represents how we should like to see our industrial society behave. But what we have in the real world is the mixed phenomenon of 'cyclical growth'.' Recently a number of attempts have been made to explain this phenomenon, and yet the most crucial question of comparative dynamics still remains largely unanswered, namely: 'By what mechanism, if any, are these two [the rate of growth of effective demand and the rate of growth of productive capacity] brought into alignment ? '2 For the prevailing models would have us believe as if intrinsically irregular exogenous shocks could logically account for essentially regular cycles common to all growing advanced market economies,3 as if the structure of a growing economy were fundamentally so unstable as to require exogenous constraints (e.g. a ceiling and a floor) for recurrent oscillations,4 or as if self-limiting cycles capable of occurring without growth could realistically be associated with growth.5 This note implies a criticism of all these models of cyclical growth. However, the main purpose of this note is to suggest an alternative approach to cyclical growth in terms of purely endogenous variables and in the belief that such an approach would be more useful in clarifying the essentially self-generating nature and process of cyclical growth without resort to artificial exogenous constraints (including non-economic erratic shocks) or to superfluous autonomous growth factors. The main proposition of this note is that endogenously determined investment is the common maker of cycles and growth. I shall implement this proposition by building a different model of cyclical growth on appropriate assumptions. Our comparative dynamic system has its demand side and its supply side. The latter side presents no particular difficulty, though the choice


Traumatic injuries are common in green iguanas. In this clinical report, we follow out the surgical management and antibacterial therapy of a bite wound with loss of muscle tissue in one-year-old green iguana (Iguana iguana), referred to the Small Animal Clinic at the Faculty of Veterinary Medicine, Stara Zagora, Bulgaria. Some clinical and radiological signs of diagnostic importance and the condition of the lizard after the treatment performed are described. This is the first report about the therapy of a bite wound with muscle tissue loss in a green iguana in our country.


Mars Sample Return (MSR) is the highest priority science mission for the next decade as recommended by the recent Decadal Survey of Planetary Science. This paper presents an overview of a feasibility study for a MSR mission. The objective of the study was to determine whether emerging commercial capabilities can be used to reduce the number of mission systems and launches required to return the samples, with the goal of reducing mission cost. The major element required for the MSR mission are described and include an integration of the emerging commercial capabilities with small spacecraft design techniques; new utilizations of traditional aerospace technologies; and recent technological developments. We report the feasibility of a complete and closed MSR mission design using the following scenario that can start in any one of three Earth to Mars launch opportunities, beginning in 2022: A Falcon Heavy injects a SpaceX Red Dragon capsule and trunk onto a Trans Mars Injection (TMI) trajectory. The capsule is modified to carry all the hardware needed to return samples collected on Mars including a Mars Ascent Vehicle (MAV); an Earth Return Vehicle (ERV); and hardware to transfer a sample collected in a previously landed rover mission, such as the Mars 2020 rover, to the ERV. The Red Dragon descends to land on the surface of Mars using Supersonic Retro Propulsion (SRP). After previously collected samples are transferred to the ERV, the single-stage MA V launches the ERV from the surface of Mars to a Mars phasing orbit. The MA V uses a storable liquid, pump-fed bi-propellant propulsion system. After a brief phasing period, the ERV, which also uses a storable bi-propellant system, performs a Trans Earth Injection (TEl) burn. Once near Earth the ERV performs Earth and lunar swing-bys and is placed into a Lunar Trailing Orbit (LTO)an Earth orbit, at lunar distance. A later mission, using a Dragon and launched by a Falcon Heavy, performs a rendezvous with the ERV in the lunar trailing orbit, retrieves the sample container and breaks the chain of contact with Mars by transferring the sample into a sterile and secure container. With the sample contained, the retrieving spacecraft, makes a controlled Earth re-entry preventing any unintended release of pristine Martian materials into the Earth's biosphere. Other capsule type vehicles and associated launchers may be applicable. An MSR launch in 2022 becomes the preferred option if the Mars 2020 rover is the previous sample caching vehicle. The analysis methods employed standard and specialized aerospace engineering tools. Mission system elements were analyzed with either direct techniques or by using parametric mass estimating relationships (MERs). The architecture was iterated until overall mission convergence was achieved on at least one path. Subsystems analyzed in this study include support structures, power system, nose fairing, thermal insulation, actuation devices, MA V exhaust venting, and GN&C. Best practice application of loads, mass growth contingencies, and resource margins were used. For Falcon Heavy capabilities and Dragon subsystems we utilized publically available data from SpaceX; published analyses from other sources; as well as our own engineering and aerodynamic estimates. Earth Launch mass is under 11 mt, which is within the estimated capability of a Falcon Heavy, with margin. Total entry masses between 7 and 10 mt were considered with closure occurring between 9 and 10 mt. Propellant mass fractions for each major phase of the EDL - Entry, Terminal Descent, and Hazard Avoidance were derived. An assessment of the entry condition effects on the thermal protection system (TPS), currently in use for Dragon missions, showed no significant stressors. A useful mass of 2.0 mt is provided and includes mass growth allowances for the MA V, the ERV, and mission unique equipment. We also report on alternate propellant options for the MA V and options for the ERV, including propulsion systems; crewed versus robotic retrieval mission; as well as direct Earth entry. International Planetary Protection (PP) policies as well as verifiable means of compliance with both forward and back contamination controls, will have a large impact on any MSR mission design. We identify areas within our architecture where such impacts occur. This work shows that emerging commercial capabilities can be effectively integrated into a mission to achieve an important planetary science objective.


The Occupational Safety and Health Administration (OSHA) record‐keeping rule 29 CFR part 1904.10, changed the definition of recordable hearing loss and created a separate column on the OSHA 300 form to record noise‐induced hearing loss (NIHL). In an effort to identify possible effects of the record‐keeping rule change, an informal written survey was distributed at the National Hearing Conservation Association (NHCA) annual conference in February, 2006. NHCA conference attendees, because they specialize in hearing loss prevention, are likely to be familiar with hearing conservation issues so their perceptions are of particular interest. A total of 36 attendees, including audiologists, audiometric technicians (OHC), industrial hygienists (IH), mobile test company owners, occupational medicine physicians (OMP), and occupational health nurses (OHN) completed the ten‐question survey. In summary, there appears to be a consensus that the everyday practice of hearing loss prevention has been affected by the record‐keeping rule change, with both positive and negative influences. Employers seem to be paying more attention to HLPPs, which is, by itself, a positive outcome. Somewhat alarming however, is the finding suggesting that recordable STSs may be being ''lined‐out'' or ''denied'' inappropriately in order to keep recordable rates artificially low.


Abortus provocatus is a controversial case until now because there are pros and cons in the community.In criminal law of Indonesia abortion is a crime provocatus.Perpetrators in the case of abortion provocatus by reason of the failure of contraception is Pregnancy (dader) who want abortion occurs in an abortion, pregnant women can not do the criminal act itself but because of the people assisted by the helper perpetrators will also be punished.


A case of patent who was admitted to the unit because of lung tumor is presented in his report. After receiving the cytological diagnosis of the carcinoma non-microcellulare from biopsy taken during bronchoscopy patient was qualified for operative procedure. Upper left lobectomy was performed. During the histological investigation of postoperative specimen the diagnosis of adenocarcinoma GI was established. Furthermore in subsegmental bronchus small tumor which didn't infiltrate the whole bronchial wall was noticed. The diagnosis of carcinoma planoepitheliale keratodes GII was established. For each cancer I stage of disease was established (pT1N0M0). Postoperative period was uncomplicated. In control X-ray after 3, 6, 9 months cancer recurrence wasn't diagnosed. General condition of patient was very good (WHO 0). Patient return to the complete physical activity.


Out‐of‐pocket and indirect (OPI) costs play an important role in prostate cancer (PCa) outcomes research. We sought to analyze OPI costs of newly diagnosed PCa patients receiving either radical prostatectomy (RP) or external beam radiation therapy (EBRT).


This program of research identified a number of novel roles for peptides and neurotransmitters found in the suprachiasmatic nuclei (SCN) in the regulation of SCN neuronal activity and behavioral circadian rhythms. Major findings included the observations of changes in SCN cell firing rates and behavioral phase shifts induced by gastrin releasing peptide (GRP) when applied to SCN cells. GRP was demonstrated not to act primarily in concert with other peptides in a manner proposed by an earlier publication. Similar combinations of neurophysiological and behavioral studies have been completed using another peptide, substance P, and are partially completed using VIP. Other studies have investigated the neurophysiological role of metabotropic glutamate receptors, and the behavioral effects of their activation or blockade. Neurophysiological studies investigated the effects of melatonin and of serotonin on photic responses of SCN cells and evaluated putative antagonists for these effects. Antagonists that acted selectively on the melatonin and serotonin receptors in the SCN were identified. Additional studies examining the neurophysiological effects of opiatergic drugs, histamine and redox agents were also completed. Work accomplished during the grant period 1. Behavioral and neurophysiological effects of light In collaboration with Dr. J. Meijer, we completed a study designed to investigate the dynamics of how single SCN cells respond and habituate to light exposures, and to compare these responses to those of the whole circadian system. We compared the firingrate responses of single SCN neurons in hamsters to continuous 15 min light presentations and to a series of eight 1 min pulses separated by 1 min periods of darkness. The neurophysiological responses were then compared to the behavioral phase-shifting responses of hamsters exposed to trains of one, two, four or eight 1 min light pulses. The neurophysiological results indicated that responses to light pulses at the end of the train were robust and similar in amplitude to those at the beginning, while there was a gradual reduction of firing rate for most cells during the latter portion of a continuous 15 min light exposure. Behavioral results indicated that additional light pulses added additional phase-shifting effects, but that later pulses in the train added progressively less phase shift. Thus, neurophysiological responses (assessed as the total number of spikes counted during a train of light pulses) increased linearly with added light pulses, while phase-shifting effects increased at most logarithmically with added pulses. Firing rate increases in SCN cells may faithfully reflect photic input to the SCN, but the pacemaker appears to introduce non-linearities in the functional response to this input. These results have been published [1]. 2. Neurophysiological effects of melatonin The pineal hormone melatonin plays an important role in the regulation of circadian rhythms in vertebrates other than mammals, but its role in mammals is less clear. We have been studying the effects of melatonin on photic responses of SCN and IGL cells, and for comparative purposes, also on activity of cells in the hippocampus and cortex. In addition, we began to study the effects of naphthalenic melatonin analogs manufactured by Servier (Paris), some of which are supposed to be potent melatonin receptor agonists and antagonists. After we had completed our initial studies using these analogs in 1994, Servier proposed a contract to conduct further studies on these drugs with their financial support. We have published several abstracts and reports based on our initial studies of melatonin and its naphthalenic analogs [5,11,16,19,28,30,33]. Our first studies concerned the role of daily pineal melatonin rhythms in the regulation of rhythmic sensitivity to melatonin and firing-rate rhythms in the hamster SCN slice preparation. We examined the effects of both acute exposure to constant light for several days (to suppress melatonin secretion) and of pinealectomy a week before slice preparation on the rhythm of SCN cell sensitivity to melatonin and on SCN cell firing-rate rhythms. We found that either treatment flattened the rhythm of melatonin sensitivity, suggesting that the presence of melatonin may modulate the availability of its own receptor [2,3], a conclusion that has been confirmed by recent receptor-binding studies, although not all results are consistent with it. Our results also indicated that pinealectomy reduced the amplitude of the firing-rate rhythm in the slice [3]. This result suggests a mechanism whereby pinealectomy or loss of normal melatonin levels (e.g., with aging in humans) may interact with other Stressors on the circadian clock mechanism to produce severe rhythm disruptions. We subsequently studied the effects of melatonin as a modulator of photic responses in both the IGL and the SCN of hamsters. These studies involved single-unit recordings in urethane-anesthetized animals. We found that melatonin reduced the photic responses of both IGL and SCN cells in a dose-dependent manner and had a generally inhibitory effect on them, although it activated a small proportion of cells, as it did in the slice preparation [5,11]. Unlike the effects of serotonin (5-HT), the effects of melatonin could not be attenuated by the 5-HT receptor antagonist metergoline, suggesting that the effects are mediated by a melatonin receptor and not by the interaction of melatonin with serotonin receptors. In our initial studies using Servier's naphthalenic analogs of melatonin, we demonstrated that S-20098 acts as a potent agonist with suppressive effects on photic responses of both SCN and IGL cells. These effects were similar to those of melatonin but were somewhat more sustained, at least when the agonist was injected intraperitoneally (IP). The putative melatonin antagonist S-20928 actually acted as a partial agonist when injected IP at higher doses, but at low doses did not alter photic responses by more than 10-20%. Co-application of S-20928 (at doses that lacked agonist activity) along with melatonin or S-20098 potently attenuated the agonists' effects on SCN cell photic responses. This drug appears, therefore, to act as a specific melatonin antagonist at low doses, despite having mixed properties at higher doses [11]. These results are illustrated in Fig. 1, below.


The stability of liquid layers in a porous medium under the action of viscous and surface forces is described. An extension of previous studies on the stability of a single interface in a porous medium is presented as the basis for solutions to many problems of practical interest where flow in porous media are involved.


The development of Guangdong heat treatment industry by the guidance of market economy are Introduced in this paper.In the facing of the progress of new type Guangdong industrialization,the countermeasures are analyzed.


List of Plates Contributors Acknowledgements Introduction: On Invisibility and Mortality 1. What is a Nice Lesbian Like You, Doing in a Film Like This? 2. The Meaning of Treut 3. Oranges are Not the Only Fruit: Reaching Audiences Other Texts Cannot Reach 4. Salmonberries: Consuming kd lang 5. Sex in the Summer of '88 6. 'If You Don't Play, You Can't Win': Desert Hearts and the Lesbian Romance Film 7. Portrait of a Production 8. The Space Between: Daughters and Lovers in Anne Trister 9. On Not Being Lady Macbeth: Some (Troubled) Thoughts on Lesbian Spectatorship 10. Girl's Camp? The Politics of Parody 11. Looking at Pumping Iron II: The Women 12. Desire and Design - Ripley Undressed 13. Interview with Andrea Weiss and Greta Schiller


A biotype of Scirpus juncoides roxb. from Kimje, Jeonbuk, showed 58- to 236- fold resistance compared to susceptible biotype, based on values determined in seed bio- assay for seven sulfonylurea herbicides; azimsulfuron, bensulfuron-methyl, cinnosulfuron, cyclo- sulfamuron, halosulfuron-methyl, imazosulfuron, pyrazosulfuron-ethyl. The resistant biotype was also differentiated from the susceptible biotype, in terms of growth recovery from herbicidal damages. When transplanted in untreated soil after pre-treatment with level of bensulfuron- methyl and pyrazosulfuron-ethyl, the seedlings of resistant biotype showed rapid enhancement of growth at whole plant level for 90 days after transplanting. For mature plants, it is an effective bioassay that cuttings from 4 to 5 leaf stage of Scirpus juncoides were incubated in the culture solution containing the herbicides for 15 days, and then new roots regenerated were measured. By this method, at least 20-fold resistance was detected in the resistant biotype compared to the susceptible biotype. Using the in vivo acetolactate synthase assay, accumulation of acetoin of the resistant biotype in untreated condition was higher (2 to 3 fold higher) than that of the susceptible biotype during unit period. The resistant biotype demonstrated 12- to 28-fold resis- tance, based on I50 values of the seven sulfonylureas. The significant correlationship was also present between GR50 and I50 values of the sulfonylurea herbicides, indicating the degree of herbicidal sensitivity between the two biotypes was caused by at least the differences in inhibi- tion of acetolactate synthase. However, both biotypes of Scirpus juncoides were inhibited 84% to 100% with butachlor, oxadiazon, pretilachlor and thiobencarb having different action site from sulfonylurea herbicides


Amplification of the 3q region has been identified as a useful biomarker for the diagnosis and treatment of squamous cell carcinoma (SqCC). This region contains genes such as PIK3CA and YEATS2, which have been linked to the prognosis of SqCC.


During this, the Body Mass Index (BMI) is used as a measuring tool to assess the nutritional status of adults. Health Kebomas Gresik has a problem in terms of determining the nutritional status of adults which in determining the nutritional status of adults still use the poly nutritional formula which in its determination IMT uses only two indicators alone are weight and height possessed. To determine the nutritional status of adults is not enough if it only uses two indicators of weight and height alone because there are other attributes that should be included in the assessment. By using data mining techniques classification using Learning Vector quantization, prediction or classification can be done. There is a wide - range of methods to classify the data and each method has its advantages and disadvantages of each. Learning Vector Quantization have excess generating an error value is smaller than other artificial neural networks such as back propagation, other than that generated model methods Learning Vector quantization can be updated gradually. Based on the results of research and discussion conducted, LVQ algorithm can recognize patterns and were able to classify the nutritional status of adults to use traditional anthropometric data includes data age, weight, height, waist circumference and hip circumference with an accuracy value reached 86.67%.


Objective To explore the effect of the nursing work on the meniscus injury of knee joint injury in high resolution CT angiography.Methods A total of 20 patients with meniscus injury were selected and randomly divided into two groups with each 10 cases.Observation group was adopted careful nursing and control group was adopted conventional nursing.The mental state,the occurrence of adverse condition and image quality were observed between two groups in the CT examination.Results During puncture there was no patient with hemorrhage and petechiae in observation group,but one patient with hemorrhage and one patient with petechiae in control group.The difference was significant (P < 0.05 ).In observation group,the image quality was grade 1,but in control group,7 cases of grade 1,2 cases grade 2,1 cases grade 3,there was significant statistical difference ( P < 0.05 ).Conclusions Careful nursing on meniscus injury of knee joint in high resolution CT angiography can reduce the incidence of adverse reaction,improve the psychological status of patients and improve the diagnostic image quality.

Key words:
High-resolution CT angiography; Meniscus; Nursing


Chatbots are becoming more common in modern society, but there are almost no studies that explore both the differences and causes that divides human communication from communication with a chatbot. ...


— We develop a framework model for the development of multi-step quasi-Newton methods which utilizes values of the objective function. The model developed here is constructed using iteration genereted data from the m+1 most recent iterates/gradient evaluations. The model hosts double free parameters which introduce a certain degree of flexibility. This permits the interpolating polynomials to exploit available computed function values which are otherwise discarded and left unused. Two new algorithms are derived for which function values are incorporated in the update of the inverse Hessian approximation at each iteration, in an attempt to accelerate convergence. The idea of incorporating function values is not new within the context of quasi-Newton methods but the presentation made in this paper constitutes a new approach for such algorithms. It has been shown in several earlier works that Including function values data in the update of the Hessian approximation numerically improves the convergence of Secant-like methods. The numerical scores of the new methods are reported with promising performance results.


The present invention provides with a CD20-specific binding molecules of single doses, the materials and methods for abnormal activity of B cells to treat diseases involving. In one aspect, the present invention involves administration of a single dose of CD20-specific binding molecules of the therapeutically effective amount to a patient, having a disease associated with B cell abnormal activity or has a suspected there is provided a method of treating a cracked target. In one embodiment, CD20-specific binding molecule is a CD20-specific small modular immunopharmaceutical (SMIP).


An old Spaniard has been in exile for twenty years but still sees himself as a passionate anarchist of the civil war. But now, menaced by the even greater fear of his own imminent death, he suddenly dares himself to return for a last encounter - a matador to Franco's bull.


— In this article, we try to see if the topological isomorphism that exists between the group R/Z and the unitary group U = {z ∈ C/ |z| = 1} can be generalized to some other situations. We show that this isomorphism exists algebraically in all situations : for a given algebraically closed field C and a given involution c of C, the groups U(C, c) = {z ∈ C/ zc(z) = 1} and C/Z are isomorphic. We then give an example of an involution c0 of C which is not conjugated, in the group Aut(C), to the complex conjugacy and such that U(C, c0) is isomorphic as a topological group to C0/Z. Résumé.— Dans cet article, nous tentons de généraliser à d'autres situations l'isomorphisme de groupes topologiques qui existe entre le groupe R/Z et le groupe unitaire U = {z ∈ C/ |z| = 1}. Nous montrons que cet isomorphisme existe algébriquement en toute généralité : pour tout corps algébriquement clos C et toute involution c de C les groupes U(C, c) = {z ∈ C/ zc(z) = 1} et C/Z sont isomorphes. Nous donnons ensuite un exemple d'involution c0 de C qui n'est pas conjuguée, dans le groupe Aut(C), à la conjugaison complexe et telle que U(C, c0) soit topologiquement isomorphe à C0/Z.


A facile construction of a heteropolycyclic framework is developed by exploiting the dual functionalization of allene. On treatment of phenethyl alcohol or amine bearing a terminal allene with the ...


Background: The purpose of this study was to examine the cost-effectiveness of renal transplantation and hemodialysis among end-stage renal disease patients.Methods: Empirical data on treatment costs were collected from five hospitals in Korea. We used European Renal Association-European Dialysis and Transplant Association registry data for transition probability. Quality adjusted life year (QALY) values were derived from the literature. A Markov model was used for predicting the cost utility of transplantation and hemodialysis over a 10-year period.Results: Renal transplantation was less costly and resulted in a better outcome than hemodialysis. The cost per QALY gained was 19,450 thousand won in transplantation patients, whereas it was 36,514 thousand won per QALY gained in hemodialysis patients. Conclusions: Although the cost of the first year after transplantation was expensive, transplantation was more effective over 2 years and was less costly than hemodialysis. The results suggest that transplantation is more cost-effective than hemodialysis in Korea.Key Words: Cost-effectiveness analysis, Cost-utility analysis, Renal transplantation, Hemodialysis, End-stage renal disease (ESRD)중심 단어: 비용-효과분석, 비용-효용분석, 신장이식, 혈액투석, 말기신부전책임저자:함명일, 아산시 신창면 읍내리 646순천향대학교 의료과학대학 보건행정경영학과, 336-745Tel: 041-530-3035, Fax: 041-530-3085E-mail: email@example.com접수일 : 2010년 4월 5일, 심사일 : 2010년 5월 28일게재승인일 : 2010년 7월 6일


We revisit the problem of local persistence in directed percolation, reporting improved estimates of the persistence exponent in 1+1 dimensions, discovering strong corrections to scaling in higher dimensions, and investigating the mean field limit. Moreover, we examine a graded persistence probability that a site does not flip more than m times and demonstrate how local persistence can be studied in seed simulations. Finally, the problem of spatial (as opposed to temporal) persistence is investigated.


This paper presents a fault diagnosis method for detecting pitch sensor offset fault according to the mechanical structure characteristics of wind turbine. The method establishes corresponding relation between the change of pitch angle and the minute displacement which produced by the force acting on tower of wind turbine. It is based on the change of displacement to diagnosis whether the fault occurs. With regard to the large noise of sensors, we adopt the multi-innovation Kalman filter to enhance the estimation accuracy and convergence speed. The simulation results show that the multi-innovation Kalman filter based method can diagnose the fault effectively and is better than the common Kalman filter.


This paper mainly proposes an efficient modified particle swarm optimization (MPSO) method, to identify a slider-crank mechanism driven by a field-oriented PM synchronous motor. The parameters of many industrial machines are difficult to obtain if these machines cannot be taken apart. In system identification, we adopt the MPSO method to find parameters of the slider-crank mechanism. This new algorithm is added with "distance" term in the traditional PSO's fitness function to avoid converging to a local optimum. Finally, the comparisons of numerical simulations and experimental results prove that the MPSO identification method for the slider-crank mechanism is feasible.


Bacterial infections thatarise fromtheflora oftheoropharynx, female genital tract, or distal bowelare often polymicrobial andinclude bothanaerobic andnonanaerobic microorganisms. Although a variety ofantimicrobial agents may often beeffective fortreatment ofsuchinfections, many experts recommend thatinitial, empirical treatment ofsevere infections include theuse ofan aminoglycoside for coverageofthefacultative andaerobic gram-negative bacilli andtheuse ofanother agent,suchascefoxitin, chloramphenicol, clindamycin, metronidazole, or ticarcillin,for coverageofanaerobic bacteria (2,4,11). Eachofthese regimens includes anaminoglycoside andtherefore carries therisk of oto-andnephrotoxicity andalsonecessitates measurement ofdruglevels inserum,frequent serum creatinine determinations, andaudiometric evaluation. We considered thepotential utility ofvarious combinations ofagentsthat might beusedforthetreatment ofmixed orpolymicrobial infections. Onesuchcombination isclindamycin, whichhasexcellent activity versusanaerobic bacteria(10), plus ceftazidime, whichhasexcellent activity versus facultative andaerobic gram-negative bacilli (8); bothagents alsohavereasonably goodactivity against Staphylococcus aureus andmostStreptococcus species (5,8).Because combination chemotherapy may sometimes haveunforeseen andundesirable sideeffects, we felt that itwas important to study theeffect ofcombining clindamycin andceftazidime on their antimicrobial activities invitro.


In this paper, we justify the limit from the Navier–Stokes system in a thin domain to the hydrostatic Navier–Stokes/Prandtl system for the convex initial data with Gevrey 9/8 regularity in x.


Many governments and international organizations in Pakistan have introduced various reforms to promote the justice system in the country, but their efforts have ended in vain. The justice system in Pakistan has not been able to provide justice to common citizens. The reforms were aimed at decreasing the time span trials usually take in Pakistan and minimizing the cost of litigation; however, the basic purpose of the justice system, that is, the dispensation of justice, has remained unfulfilled. The reforms strengthened judicial hierarchy, improved infrastructures, and amended certain procedural laws but did nothing to address the real issues that were hindering the deliverance of justice to the common people. The legal fraternity and international donor agencies, who were the forces behind these reforms, have been the defenders of the formal justice system in Pakistan for reasons that are many.


Based on monthly meteorological data from 49 observatories in Hebei Plain,the climatic changes including evapotranspiration(ET),precipitation and atmosphere temperature,during the period of 1966~1999,were analyzed.The results indicated that ET of spring season was rising in the seasonal and annual variation patterns of ET at temporal scale,but declining in other seasons and annual ET changes.And the decline in summer reached significant level(P0.05),with an exponential function relation.The annual ET also showed a depressed tendency of exponential function,with an average decline rate of 0.74mm per year during the last 34 years.The precipitation in spring and winter showed a faint rising tendency while precipitation in summer and autumn seasons demonstrated declining tendency.Annual changes of precipitation presented a liner declining tendency,with a decline rate of 1.667mm per year.As far as average atmosphere temperature is concerned,seasonal and annual changes of temperature all showed a liner increasing trend,and reached highly significant level(P0.01),except for summer season.The rising rate of annual average atmosphere temperature was 0.38℃per 10 year.The average decline rate of precipitation was greater than the average decline rate of ET,with a trend of atmosphere temperature rising,which implied that climate in Hebei Plain have been changing towards arid climatic types.


A numerical simulation of the recirculating swirling turbulent flow in a swirl combustor with an annular inlet and exit was conducted.A new algebraic Reynolds stress model,both in its full form and in a simplified explicit form,and the k e model were employed in the simulations for the closure of turbulence.The calculated results were compared with the measured test data in terms of the gas axial and tangential velocities,and the three components of the gas turbulent fluctuating velocity.It is shown that the new algebraic Reynolds stress model can properly predict the large central recirculation zones in the combustor,the Rankine vortex profiles of the gas tangential velocity,and the nonisotropic features of the gas turbulence.


Abstract Head space volatiles, including 73% di-n-propyl disulfide, were collected from freshly crushed neem seeds. This compound along with previously reported diallyl disulfide (di-2-propenyl disulfide) were toxic when applied topically or as a fumigant to Tribolium castaneum adults and 8-, 12-, and 16-d-old larvae, and Sitophilus oryzae adults. Di-n-propyl disulfide significantly decreased the growth rate and dietary utilization with moderate inhibition of food consumption in both insects. The total coefficient of deterrence for this compound ranged between 68.5 and 178.6, which suggests that it has medium to very good deterrent activity vis-à-vis the treatment concentration and instar. Di-n-propyl disulfide and diallyl disulfide presented a similar effect on efficiency of conversion of ingested food, which is reduced 3-fold; this implies that both compounds are physiological toxicants. Present studies clearly demonstrate that di-n-propyl disulfide could be a potent toxicant, fumigant, and feeding deterrent for stored grain pests, if a suitable formulation and application procedure are developed.


We have designed and realized a temperature and pressure controlled cell for Neutron Reflectometry (NR) and Small Angle Neutron Scattering (SANS) that is compatible with simultaneous optical transmission and resistivity measurements. The cell can accommodate samples up to 102 mm (4 inch) in diameter, can be pressurized from vacuum up to 10 bar gas pressure and the sample temperature can be controlled up to 350°C. The four single crystal quartz windows ensure both a good neutron and optical transmission and hence can be used in combination with in-situ optical transmission measurements. We present the cell and illustrate its performance with a series of neutron reflectometry experiments performed on Ta based thin films under a hydrogen containing atmosphere.


In no description of power line channel models with time varying and frequency selecting characteristics available has any account been taken of the channel effect of energy time frequency distribution(ETFD).The classification of power line channel effects into the multiplicative and additive ETFD is proposed,which compares their differences by using three time frequency analytical methods and simulates the available slot number in every sub-carrier or the available sub-carrier number in every slot using smooth pseudo Wigner-Ville distribution(WVD).The three energy assignment methods of average or greed or cellar are also recommended,which simulates their energy time frequency assignments in the given channel effect and attainable total energy.The results obtained show that the average algorithm has the lowest operational complexity and the cellar algorithm the lowest energy loss values.


Improving energy performance is an important goal for many leading manufacturers throughout the United States. These companies know that understanding and actively managing energy leads to improved profitability. A number of these companies are now turning to their suppliers, the source of much of the energy embedded into their products, and not only asking them to improve their energy footprints, but engaging with them to mentor or guide them toward energy performance improvement. In addition, an understanding of suppliers' energy use is important to companies compiling greenhouse gas (GHG) reports that include Scope 3 ("other indirect emissions") reporting under the WRI/WBCSD GHG Protocol. The U.S. Department of Energy's Better Plants Program began a Supply Chain pilot with two Better Plants partners (Legrand and United Technologies Corporation) in 2014, and plans to expand this initiative in 2015. This paper will discuss the energy-efficient supply chain efforts of these two companies and DOE's role in working with these companies and their suppliers. The paper will describe how lessons learned during the pilot phase will be applied to this initiative, as well as ongoing supply chain activities of other leading manufacturers. As importantly, the authors will synthesize outcomes from the Supply Chain Pilot with noteworthy energy efficiency-related supply chain activities from other leading manufacturers in the Better Plants program and suggest evolving best practices that any manufacturer can adopt when engaging their supply chains in energy efficiency.


Apprenticeship system is an ancient system vocational education in Britain.There have been a lot of changes in both form and content,so that the modern apprenticeship system not only inherits the traditional characteristic of learning by doing,but also incorporates the modern school education.The old apprenticeship system in Britain today attracts students with its unique glamour.


This paper presents an overview of the proposed risk management framework and how it is designed to meet the challenges usually faced by IT-centric micro and small companies when implementing risk management. The issues and challenges identified for the IT-centric micro and small companies are centered around the exposure to various risks and necessity to have a risk management approach which covers these various risks, as well as to limited resources for risk management and necessity for usable and comprehensive framework. The new framework is based on the analysis of the best practices in risk management concepts as well as direct experience from dealing with over 20 companies in South-east Europe. The segments covered by the framework include people, policy, methodology and process, and tools.


The invention discloses a centrifugal simulation system for the freeze thawing deformation of a water conveyance canal in a salty-cold region. The centrifugal simulation system consists of a centrifugal machine, a model box, a water circulation refrigerating plant and a temperature controller, wherein the model box consists of an outer box, an inner box and an interlayer filling material and is used for setting a canal model; the water circulation refrigerating plant consists of multiple semiconductor refrigerating sheets connected with one another in series and a water cooling device; the water cooling device comprises a water pipe, a water pump and a water tank; the temperature controller is used for setting and monitoring the ambient temperature in the model box so as to simulate a real site environment temperature; the model box is arranged in a basket of the centrifugal machine; the semiconductor refrigerating sheets are fixed on the top in the model box; the water circulation cooling device is arranged on a rotating arm of the centrifugal machine; refrigeration plates of the semiconductor refrigerating sheets downwards absorb heat of the canal model; heat dissipation plates of the semiconductor refrigerating sheets dissipate heat through the water circulation cooling device. The technical problems of simulation and testing in the frost heaving-thaw collapse process of the water conveyance canal under the action of a hypergravity field are solved.


Objective:To investigate the effect of pancreatic ischemia and the disturbance of lipid inflammatory mediator balance on the conversion of acute edematous pancreatitis(AEP) to acute necrotizing pancreatitis(ANP) .Methods:One hundred and three Sprague-Dawley rats were randomized in three experimental groups as follows:Sham-operated group,AEP group,ANP group.AEP was induced by pancreatic duct ligation and exocrine stimulation,ANP was induced by pancreatic duct ligation and exocrine stimulation and intravenous injection of a large dose of dextran-110(500mg/kg).Results:Three and nine hours after induction of pancreatitis,plasma and pancreatic tissue lipid peroxide levels in rats with ANP were markedly higher than that with AEP.In AEP group,plasma thromboxane B2 and 6-keto- PGF 1α remained unchanged.The plasma TXB 2 level increased significantly in ANP group than in AEP group. Ultrastructural examination demonstrated the endothelial cells separated from pancreatic capillary basal membrane and necrotized in ANP group.Conclusion:The disturbance of lipid inflammatory mediator balance may aggravate pancreatic ischemia,induce the conversion of AEP to ANP.


A limnological study of the artificial fish pond and an analysis of the stomach contents of pacu (Piaractus mesopotamicus) larvae of 2 to 45 days age were made for a period of 45 days to evaluate their feeding preferences. A preference for chlorophytes and rotifers were noted, while other planktonic species remained constant in the stomach contents. Some limnological variables were found to have strong influence on the feeding behavior of the pacu. A preference for feeding on smaller species in the first few days of larval development was also noted.


Increased data gathering capacity, together with the spreading of data analytics techniques, has allowed an unprecedented concentration of information related to the individuals' preferences in the hands of a few gatekeepers. In such context, the traditional economic literature has been attempting to frame all the data-driven economy features. Such features, although being able to bring about a more efficient matching of people and relevant purchase opportunities, also result into distortions and disequilibria, up to market failures. Data-economy market disequilibria can be decrypted by leveraging on some of the known network properties, thus obtaining general results suitable for building a new theoretical framework for economic phenomena. Starting from the hypothesis that a digital company can always benefit from an underlying network of consumers or items related to its market, their representation can indeed provide significant competitive advantages, also enhancing the platforms' capacity to implement discriminatory practices by means of an increased ability to estimate individuals' preferences. In the present paper, we propose a measure called Information Patrimony, considering the amount of information available within the system and we look into how platforms may exploit data stemming from connected profiles within a network, with a view to obtaining competitive advantages. Such information flow may eventually allow to envisage the emergence of a new hybrid price discrimination pattern, through which platforms may influence and steer individuals' purchase choices, as well as to apply different prices to different customers.


This paper tests empirically through a pilot study of the Indian Automobile Manufacturing Sector, the contribution of the variables constituting the construct Life Cycle Assessment in Green Supply Chain Practices. Also the paper establishes the reliability of the questionnaire instrument developed previously for measuring the construct Life Cycle Assessment and also for measuring the three variables that constitute the construct Life Cycle Assessment. Further the paper establishes the correlation among these three variables. Finally this paper conducts Confirmatory Factor Analysis (CFA) to arrive at one factor (linear combination of variables constituting the construct Life Cycle Assessment) to aid in measuring the construct Life Cycle Assessment. Five research questions that were framed pertaining to this research were answered.


One-year-old seedlings of Fengyang No.1were chosen as experimental materials,which were grown in six substrates with different water contents by weighting method(CK,T1,T2,T3,T4 and T5),and the difference of physiological and biochemical characteristics of C.oleifera seedlings were determined and analyzed.The results were as follows.(1) The leaf water content and the ratio of free water to bound water in CK group were the largest,and the values were 68.5% and 26.4,respectively.However,those in the other four treatments declined with the decrease of substrate water content.(2) The relative conductivity,POD activity and MDA content decreased first,and then increased with the decline of substrate water content.In addition,those values in T1 group were the smallest,being 37%,11.1 U·min-1·g-1 and 0.3 μg.g-1,respectively.(3) The content of free proline content and soluble sugar rose with the decline of substrate water,which varied from 231.4 μg.g-1and 681.4 μm.g-1in CK group to 40.4 mg.g-1 and 48.9 mg.g-1in T4 group,respectively.(4) When the substrate water content was above 90%,the reducing of leaf stomatic aperture was not beneficial for photosynthesis and respiration of the seedling.While the substrate water content dropped to less than 81%,the seedlings would suffer drought stress.Therefore,substrate water content of 81%-90% was the most suitable for seedlings growth.The substrate water content should be controlled in the appropriate range to keep seedlings growing normally in C.oleifera production.


We discuss possible definitions of structural balance conditions in a network with preference orderings as node attributes. The main result is that for the case with three alternatives $(A,\ B,\ C)$ we reduce the $(3!)^{3} =216$ possible configurations of triangles to 10 equivalence classes, and use these as measures of balance of a triangle towards possible extensions of structural balance theory. Moreover, we derive a general formula for the number of equivalent classes for preferences on $n$ alternatives. Finally, we analyze a real-world data set and compare its empirical distribution of triangle equivalence classes to a null hypothesis in which preferences are randomly assigned to the nodes.


Hashing function is an efficient way for nearest neighbor search in massive dataset because of low storage cost and low computational cost. However, it is NP hard problem to transform data points from the original space into a new hypercube space directly. Typically, the most of hashing methods choose a two-stage strategy. In the first stage, dimension reduction methods are used to project original data into desired dimensionality with real values. Then in the second stage, the real values are simply quantized into binary codes by thresholding for the most of existing methods. Although there is double-bit quantization (DBQ) strategy to improve quantization results. The existing solutions assume that the input data subject to gaussian distribution. In this paper, we propose a novel approach based on DBQ strategy, which can efficiently handle the situation under non-Gaussian distribution input. In the experiments, we demonstrate that our method is an efficient alternative to other methods based on DBQ strategy.


A practical guide to organizing and running a successful investment club. Drawing upon her own experience as a highly successful small investor, the author provides solid guidelines on everything from rounding up members and starting a club to establishing club rules and keeping records. With special tips on how to screen potential investors to make sure you get the right kinds of members, and how to find a sponsoring broker to give you additional professional advice and execute your trades. Gives you a complete course in investing--with over ten chapters of tried-and-true financial secrets--such as what to look for in a stock, how to read the market, and how to time trades.


Service design is sometimes thought of as the interface between the customer and the service provider, a design process that exists between design thinking and business practices. Service design consultancies working with service organisations are increasingly attempting to develop design thinking alongside business processes within the organisation, but if everyone becomes a 'designer' what value is placed on the design-trained service designer? What qualities, knowledge and skills does a designer offer that identifies them as a valuable business asset who has an integral place within the business process, rather than as someone brought in when the organisation wants to be seen to be 'creative' or 'innovative.' The process of design for services is well documented, however there is not much debate around whether the service designer needs to be design-trained, or of what benefits they would offer if they were. It is assumed that design tools and methods can be introduced and disseminated to non-designers, but if tools and methods are all it took to design services, what is the future for the 'designer?' From observations of students studying service design at postgraduate level and a comparative study with design and non-design staff within a service organisation, this paper aims to uncover the value and 'craft' of the designer within the context of the service design process.


Bridgeless rectifier as front-end power factor correction (PFC) converter has been obtained abundant popularity due to its praiseworthy merits of optimized power losses produced by power semiconductors. In this technical paper, novel bridgeless SEPIC rectifier with improved losses and concise circuit structure is proposed by using bidirectional power switch. Compared to conventional SEPIC rectifier, proposed SEPIC rectifier features an optimized efficiency via lessening the count of semiconductors in power-flowing path. Compared to state-of-art bridgeless SEPIC rectifiers, proposed bridgeless SEPIC rectifier possesses concise topology structure and less component. The discontinuous current mode (DCM) is presented, which has the merits of naturally PFC and the zero-current switching are analyzed. Finally, a 100W simulated model are constructed aiming to certify superiority of this new rectifier.


With placenames so ubiquitously affixed, to the landscape and to people of the Faeroe Islands, this research demonstrates the central ecological and cultural roles of geographic names in Faeroese culture. Placenames simultaneously function in the multiple subsistence pursuits, as texts of social organization, and as embodiments of personality and personhood. Place and person merge as villagers' identities come to inhabit the natural landscape and vice versa. Geography as a dominant local aesthetic leads to consideration of placenames and their associations as linkages to ecological attitudes and as foundations of self, person, and culture.


Diagnosis of lung cancer is performed using a plasmonic gold (pGOLD) chip through multiplexed near‐infrared (NIR) detection of carcino‐embryonic antigen (CEA), Cyfra21‐1, and neuron‐specific enolase (NSE) in the serum samples of patients. With ≈50‐fold enhancement of NIR fluorescence, multiplexed microarray analysis of CEA, Cyfra21‐1, and NSE in 10 μL of human serum or whole blood samples on pGOLD chip leads to markedly improved limit‐of‐quantification, limit‐of‐detection, reproducibility, and higher diagnostic sensitivity and specificity compared to traditional biochips and Luminex technology currently in use in hospitals.


Abstract This paper presents two novel contrast enhancement approaches using texture regions-based histogram equalization (HE). In HE-based contrast enhancement methods, the enhanced image often contains undesirable artefacts because an excessive number of pixels in the non-textured areas heavily bias the histogram. The novel idea presented in this paper is to suppress the impact of pixels in non-textured areas and to exploit texture features for the computation of histogram in the process of HE. The first algorithm named as Dominant Orientation-based Texture Histogram Equalization (DOTHE), constructs the histogram of the image using only those image patches having dominant orientation. DOTHE categories image patches into smooth, dominant or non-dominant orientation patches by using the image variance and singular value decomposition algorithm and utilizes only dominant orientation patches in the process of HE. The second method termed as Edge-based Texture Histogram Equalization, calculates significant edges in the image and constructs the histogram using the grey levels present in the neighbourhood of edges. The cumulative density function of the histogram formed from texture features is mapped on the entire dynamic range of the input image to produce the contrast-enhanced image. Subjective as well as objective performance assessment of proposed methods is conducted and compared with other existing HE methods. The performance assessment in terms of visual quality, contrast improvement index, entropy and measure of enhancement reveals that the proposed methods outperform the existing HE methods.


Reactive changes in macrophages/microglia and astrocytes were evaluated following spinal cord injury in normal mice of the C57BL/6J strain and in mice carrying a mutation (Wlds) which delays the onset of Wallerian degeneration in damaged axons. Crush injuries were produced at the T8 level by using an extradural approach; animals were allowed to survive for 2 days to 12 weeks, and spinal cords were prepared for immunocytochemistry using antibodies against Mac1 and glial fibrillary acidid protein (GFAP).


Two methods of blood pressure measurement in fingers are presented. One method is based on blood pulse delay-time between proximal cuff and distal pulse sensor. On the time-delay curve the first minimum which occurs during deflation determinate the diastolic pressure. The another method is based on pulse amplitude differences which occur between proximal cuff signals and distal pulse sensor signals during deflation time of proximal cuff. The amplitude difference is lowest after diastolic pressure. The pressure in the cuff corresponding to the 45% of the difference between highest and lowest amplitude difference taken from lowest value is considered to be diastolic pressure by this method. This two methods and their combination are proved to be quite accurate. The accuracy of this measurements is given as well. Blood pressure measurement on the fingers is more comfortable for blood pressure measurement than on the upper arm.


Hemophilia A is a severe bleeding disorder resulting from the lack of functional blood coagulation factor VIII. Accordingly, operations on patients with hemophilia A, except in a few cases, are performed with the administration of factor VIII. However, in those hemophilia A patients administered factor VIII inhibitor, factor VIII replacement therapy is ineffective. The treatment of hemophilic patients with factor VIII inhibitor is undertaken to utilize the hemostatic capacity of the activated forms of FVII, FIX and FX contained within prothrombin complex concentrates, which are purposely manufactured to contain Factor Eight Inhibitor Bypassing Activity (FEIBA) during surgery. Further, in the last few years, a new product, recombinant activated FVII (FVIIa, Novo-VII), which is thought to ensure hemostasis by binding, directly or in complex with tissue factor, to negatively charged phospholipids on the surface of activated platelets, has been licensed. Recently, we experienced a GB stone, with acute cholecystitis, in a fifty year old hemophilia A man treated with factor VIII inhibitor. Under medication with FEIBA and Novo-VII, a laparoscopic cholecystectomy was performed. Here, this case is reported, with a review of the literature.


In this report, we carefully study the effects of photooxidation on the Raman spectra of lead chalcogenide (PbX) quantum dots (QDs). Photoexcitation of PbS, PbSe, and PbTe QD films at 488 nm with power densities as low as 30 W/cm2 gives rise to several peaks related to both lead(II) oxide and the group VI chalcogenates (PbXO4). The amplitudes of these peaks are shown to increase with continuous laser illumination in air, but are completely absent for samples illuminated under rigorously air-free conditions. These results suggest that the ∼135 cm−1 Raman peak often assigned to an intrinsic PbX LO phonon is more likely an artifact arising from photooxidation. The myriad of potential photooxidation products formed quickly in laser-illuminated, air-exposed PbX QDs suggest that caution should be used in the assignment and interpretation of phonon spectra and phonon-mediated exciton relaxation pathways of these materials, unless the processing and experiments are conducted under air-free conditions.


309 Davidson, Donald (Herbert) (b. 1917, d. 2003; American), Willis S. and Marion Slusser Professor, University of California at Berkeley (1986–2003). Previously Instructor then Professor in Philosophy at: Queens College New York (1947–1950), Stanford University, California (1950–1967), Princeton University (1967–1969), Rockefeller University, New York City (1970–1976), University of Chicago (1976–1981), University of California at Berkeley (1981–2003). John Locke Lecturer, University of Oxford (1970). One of the most important philosophers of the latter half of the twentieth century, Donald Davidson explored a wide range of fundamental topics in metaphysics, epistemology, ethics, and the philosophies of action, mind, and language. His impact on contemporary philosophy is second only to that of his teacher W. V. O. Quine, who, along with Alfred Tarski, exerted the greatest influence on him. Given the range of his contributions, his work emerges as surprisingly systematic, an expression and working out of a number of central guiding ideas. Among his most important contributions are


Objective. The aim of this investigation was to study three groups of women presenting with possible HPV‐infection with regard to HPV‐types and cervical dysplasia.


Marxism ethnic theories and policies were creatively combined with the actual situation in national minorities' areas during the Long March in Sichuan.it helped the people of ethnic minority in Sichuan to set up the regime organization and the armed forces by applying ethnic rings and polities of the early CPC successfully.As a result,it laid the solid foundation for the victory of the Long March and the war of Chinese people's resistance against Japanese aggression.


Abstract : A 12-installation subset of the 34-installation 1975 DAPMP was evaluated to determine whether or not this 12-installation subset reflects the patterns observed from the 34 installations. The following findings were common in both the 12- and 34-installation data sets: differences in soil stratifications and the differences between top and bottom feeding fish. The differences in sediment stratifications observed in the 34-installation set were not confirmed in the 12-installation subsets. Interactions observed between fish and sediment were observed in both data sets and the transformed soil and sediment data sets. (Author)


To understand the distribution of the arboviruses in Yunnan province to provide the basis for the measures of control and prevention, the mosquitoes and sera pf patients with fever were collected in Simao and Xishuangbanna prefectures of Yunnan province, and these specimens were stored in liquid nitrogen before testing. For the isolation of viruses, C6/36 cells and the sucking mice were inoculated with specimens obtained, and the isolated viruses were identified by serological assays and molecular techniques, in which the sera of patients with fever and the healthy individuals were tested for the presence of antibodies against the isolated viruses by ELISA and HI assay. It was found that one strain of Sindbis virus from sera of patients with fever in Xishuangbanna prefecture; one strain of Batai virus from Anopheles philippinenisis in Lancang county, and 10 strains of Coltivuses from Culex tritaeniorhynchus , Anopheles sinensis. Anopheles philippinensis, and Anopheles vagus in Chuanyun district of Simao city and Lancang county.The positive rate of antibodies against Sindbis virus was 2.50% (3/120), and that against Batai virus was 4.17% (5/120) in sera of patients with fever in Xishuangbanna prefecture. The total positive rate of antibodies against Sindbis virus was 1.93% (11/571) in the sera of healthy individuals in Xishuangbanna prefecture; and those in Lancang county, Simao city, Jinghong city, Mengla and Menghai county were 4.55% (6/132), 0.89% (1/112), 1,25% (2/160), 1.96% (2/102), and 0% (0/65) respectively. It concludes that the infections due to Sindbis, Batai and Coltiviruses transmitted by mosquitoes were prevalent in Yunnan province with natural infection in healthy individuals. The further investigation for the control and prevention of these infection is necessary.


Exploring Infant Health. Conroy S, Smith M. (Pp 184, A4; £7.50.) London: Foundation for the Study of Infant Deaths.

The relation between social disadvantage and infant health is at the core of this topical and comprehensive book comprising three extensive literature reviews. It is timely in view of the recent publication of the Acheson report into health inequalities ( Inequalities in health: report of an independent inquiry . London: HMSO 1998).

Parental smoking is a known risk factor for a range of adverse infancy and childhood outcomes. Socioeconomic status is a risk factor for the same adverse outcomes. The review presents unequivocal evidence for the link between increasing social disadvantage and parental smoking. The problems of disentangling the influence of these related factors on sudden unexpected death of infants (SUDI) …


New media marketing, the marketing model in the context of new era for companies, is right at the rapid development. How to utilize the power of Wanghong and new media effectively to serve corporate marketing much better is worth exploring. Based on new media marketing, this paper discusses the influence of word-of-mouth of Wanghong on new media marketing strategy and puts forward the policy suggestion on practice of marketing in the way Wanghong affects consumer behavior. Keyword—new media marketing; opinion leader; Wanghong; word-of-mouth


Junoy, J., Montalvo, S., Roldan, C. and Garcia-Corrales, P. 2000. Ultrastructural study of the bacillary, granular and mucoid proboscidial gland cells of Riseriellus occultus (Nemertini, Heteronemertini). — Acta Zoologica (Stockholm) 81: 235–242.

The ultrastructure of six types (G5-G10) of proboscidial gland cells whose cell necks emerge independently on the epithelium surface is analysed and compared with data from other nemerteans. These types differ in cytological features, as well as in the morphology of their respective secretory granules. Secretory granules of the types G5 and G6 have a bacillary shape, and differ from each other based on their contents and dimensions. Secretory granules of the types G7 and G8 are spherical to ovoid; type G8 gland cells are monociliated, and their secretory granules contain a paracrystalline material. Types G9 and G10 gland cells are typically goblet-shaped; secretory granules in the type G9 have a spherical shape, contain a homogeneous electron dense material and maintain their individuality, whereas those of the G10 type are elongate and have fibrillar contents, showing a tendency to fuse before they are extruded. The mucus sheet of the proboscis is responsible for lubrication of its epithelial surface. Secretion products of type G10 gland cells form the background substance of this mucus, and those of the G5 type confer stickiness to it. Type G9 gland cells could provide the toxic component to the mucus, and type G7 and G8 gland cells could be concerned with the production of enzymatic secretions.


SUMMARY Objective: The purpose of this study was to evaluate the stress distributions in the mandible produced by orthopedic chincup forces. Material and Method: A three-dimensional finite element model (FEM) of the mandible was constructed from a dry human mandible via computerized tomography (CT) to investigate the stress regions. An orthopedic chincup force of 400 grams (3,92 N) was applied from the simphysis region. The stress regions were investigated by finite element analysis (FEA). Results: It is found out that the tensile stress regions were mainly located at the inner surface of the coronoid process with the highest value of 5 MPa and no significant tensile stress values were observed at the outer regions. The maximum compressive stress value of -5 MPa was observed at the outer part of the region between the condylar and coronoid processes. Conclusion: It is observed that mandibular body has been subjected to higher stress than condyle. Chincup appliance was appeared to affect the coronoid process region the most.


Radar based microwave imaging technique has great potential for breast cancer detection [1]. It has been demonstrated by recent experiments that the data-adaptive radar microwave imaging reveals good image resolution [4]. However, purely scattered energy based image reconstruction methods can face major challenges in differentiation since the fibroconnective and glandular tissues which could have similar dielectric properties as that of malignant tissues [5]. It has been proposed that the morphological features of the tissue can differentiate the benign from malignant tissues due to their irregular, spiculated shapes [3]. Thus to efficiently differentiate the healthy, benign and breast tissues, this paper proposes a method that combines a novel data-independent beamformer called MWDAS method with Matrix Pencil (MP) method to first localize the suspicious region and then extract the resonant frequency and damping factor of complex natural resonance (CNR) of the malignant tissues [2]. We employ FD-TD based computational 2D and 3D breast models for testing our method.


This electric vacuum cleaner suction tool (100) is provided with a suction tool body (1), a connector tube part (2), and wheel parts (3). The connector tube part (2) has a first connector tube (7) connected at one end to the suction tool body (1), and a second connector tube (8). The wheel parts (3) have a wheel (10) and a wheel support element (11) supporting the wheel (10). The wheel support element (11) is attached to the lower side of the second connector tube (8), and an attachment shaft (S4) for attaching the wheel support element (11) to the second connector tube (8) is formed such that the front side thereof slopes downward along the longitudinal direction of the second connector tube (8), the attachment shaft angle (θ0) formed by the attachment shaft (S4) and a surface being cleaned (F) being constituted as an acute angle. An electric vacuum cleaner suction tool (100) affording improved ease of operation of the electric vacuum cleaner (200, 300) is achieved thereby.


Settlement of ne-grained soils is often governed by a consolidation process which involves quite large strains. The classic, one-dimensional consolidation formula is based on the small strain theory, although it is still practically useful. Since strains are relatively large during the consolidation process, the overall behavior of the medium is geometrically nonlinear. In this paper, a coupled consolidation analysis was carried out to predict the consolidation settlement of ground beneath an embankment, as a case study, representing the feasibility of large strain consolidation analysis. A two-dimensional,
updated Lagrangian, large deformation, nite element formulation was employed to simultaneously solve the transient flow and the deformation equations which constitute the coupled consolidation equations. It was followed by the development of a code in the MATLAB environment to solve the required equations, with further application to a case study in Iran. In addition, analyses were performed by one-dimensional conventional methods and compared with the results obtained by the nite element
procedure. Predictions made by large deformation nite element analysis, in comparison to those obtained based on small strain assumptions and conventional methods, appeared
to be more accurate, although the required computational eort was much higher, owing to frequent recomputation of the stiness matrix.


Transistor size optimization is an important aspect of circuit design. Small and non-complex circuits can be designed easily using manual calculations and circuit simulations. But, as the complexity of circuits increases, manual design becomes too difficult and time consuming. Therefore, tools and techniques for automatic transistor sizing are of great importance in the area of circuit design. The goal of this paper is to implement Genetic Simulated Annealing algorithm as a tool for transistor sizing, and compare its performance with Simulated Annealing, one of the most popular optimization algorithm in use today. The algorithms have been tested on four different digital circuits and the results collated and compared in this paper.


Motility of endothelial cells is a requirement for the vascularization of solid malignancies. While tumors have been shown to produce a host of angiogenic factors, including TGF-β, the mechanisms by which such factors regulate endothelial cell motility have not yet been defined. Thus, the role of the serine/threonine phosphatase PP-1 in regulating endothelial cell motility and cytoskeletal architecture was studied. The present study demonstrated that TGF-β stimulation of motility is dependent on PP-1. Likewise, TGF-β was shown to up-regulate paxillin expression through a process that was PP-1 dependent. The interplay between PP-1 and TGF-β was further observed by the induction of cell rounding and the loss of paxillin-actin co precipitations upon PP-1 inhibition and the compensation for these effects by TGF-β. Studies initiated to determine how PP-1 might regulate motility showed its role in maintaining cytoskeletal organization and its capacity to directly dephosphorylate the focal adhesion scaffolding protein paxillin. These studies suggest that the interplay between TGF-β and PP-1 regulates the motility of endothelial cells that is critical to the process of angiogenesis.


A method for making chemical evaporating apparatus into the atmosphere, which comprises a receiving section for receiving a cassette, the cassette storing the chemical. The receiving portion has an opening (4) and a recess, the cartridge is inserted into the recess. The apparatus further comprises a heater portion (11), and for being inserted into the receiving portion of the heater (11) in contact with the chemicals when energized and allowed to evaporate in the cassette. Hole portion (3) so that the chemical formulation of which is guided by evaporation into the atmosphere. The groove and the cassette receiving portion has a portion for forming an interference fit, so that the cartridge relative to the heater portion (11) is positioned at a predetermined position.


Abstract An optimization problem for a Boussinesq equation system will be formulated. We are looking for a temperature profile or an appropriate velocity on the boundary of the considered region of the thermal coupled flow problem to induce a forced convection, which implies a velocity field close to a prescribed one. For such tracking type optimization problems with tracking type minimization functionals, the evaluation of the first-order necessary optimality condition leads to an optimality system consisting of the forward (primal) and adjoint (dual) mathematical model. Besides the derivation of the optimality system we discuss aspects of numerical solution, e.g. the spatial and time discretization and the iteration method for the solution of the resulting coupled nonlinear primal and dual problem in this paper. The optimization concept will be applied to a crystal growth flow and results of two-dimensional and three-dimensional model problems will be presented.


SUMMARY Water stress induces some physiological changes in plants and has cumulative effects on crop growth and yield. Field experiments were conducted to study the effect of deficit irrigation (DI) on yield and some physiological parameters in cotton and maize in a sequential cropping system. Creation of soil moisture gradient is indispensable to explore the beneficial effects of partial root zone drying (PRD) irrigation and it could be possible only through alternate deficit irrigation (ADI) practice in paired row system of drip layout that is commonly practiced in India. In the present study, PRD and DI concepts (creation of soil moisture gradient) were implemented through ADI at two levels of irrigation using drip system. Maize was sown after cotton under no till condition without disturbing the raised bed and drip layout. Relative leaf water content (RLWC) and chlorophyll stability index (CSI) of cotton and maize were reduced under water stress. A higher level of leaf proline content was observed under severe water-stressed treatments in cotton and maize. RLWC and CSI were highest and leaf proline content was lowest in mild water deficit (ADI at 100% crop evapotranspiration once in three days) irrigation in cotton and maize. The same treatments registered higher values for crop yields, net income and benefit cost ratio for both the crops.


The data is for figures in the paper "Phase-field modelling of gravity-capillary waves on a miscible interface" to be published in European Physical Journal E.


The utility model provides a ratchet wheel and a wheel hub. The ratchet wheel comprises at least a chain wheel, a plurality of grooves and a plurality of detents. The chain wheel is arranged at one side of the ratchet wheel, and the grooves are arranged at the other side of the ratchet wheel. The grooves are provided with first grooves and second grooves which are symmetrical in pairs, and the shape of the first grooves and the second grooves is arc. In addition, the first ends of the detents are arranged inside the first groove, and the second ends of the detents are exposed outside the groove. Furthermore, the first ends of elastic sheets are arranged inside the second groove, and the second ends of the elastic sheets are closely connected with the detents.