: Supplementation of dairy products with various dietary additives is necessary to enhance health condition. There is increasing demand for such functional dairy product for public health. Chia seeds have high nutritive value and several health benefits. The present study was planned to evaluate the nutritive value of ice milk sample which prepared with chia seeds as a stabilizer. Our previous studies revealed that 6% (w/w) chia seeds gave acceptable and palatable organoleptic properties beside the favorite physical properties of the resultant ice milk. So this ratio was a guide in the present study. Two treatments were achieved; the first was prepared by using 0.5% Carboxy methyl cellulose as commercial stabilizer and labeled (C) while the second sample was prepared by using 6% chia seeds powder and named (T). Free amino acids, free fatty acids, vitamins, minerals content and antioxidant activity were determined in the two samples. The dietary fibers were mathematically calculated. The obtained data indicated that the level of Glutamic, Glycine, Histidine. Arginine, Proline, Tyrosine, Valine, Methionine, Cysteine, Isoleucine, Leucine, Phenylalanine, Lysine acids were higher in fortified sample rather than control one. Fatty acids profile indicated that fortified sample was rich in ALA and poly-unsaturated fatty acids. It could be noticed also that the fortified sample was rich in vitamin A as well as vitamin D when it is compared with control sample. Large variations were observed in the content of vitamin 3 B between the two samples. For minerals content, it was clear that chia-ice milk sample had the higher level 12 of Ca, Fe, P, Mg and Zn. Antioxidant activity was more pronounced (45.6%) in fortified sample rather in control one (8.1%). Obtained results revealed that 6% (w/w) chia seeds when used as stabilizer, enhanced the nutritive value of ice milk sample.


WHEN COMPARED WITH ACCIDENT RECORDS FOR1970, 1974 SHOWED A CONSIDERABLE REDUCTION IN THE NUMBER OF ACCIDENTS. THIS TENDENCY WAS ALSO EVIDENT IN ACCIDENTS INVOLVING CHILDREN AND ADOLESCENTS ALTHOUGH IN THIS CASE, THE DECLINE WAS CLEARLY FAR BEHIND THE AVERAGE. IT WAS NOTICEABLE THAT ACCIDENTS INVOLVING CHILDREN UNDER 6 YEARS WERE OF A PARTICULARLY MINOR NATURE. IN REGARD TO CAUSES, IT MAY BE SAID THAT CHILDREN IN THE 3 TO 9 AGE GROUP ARE MOSTLY RESPONSIBLE FOR THE ACCIDENTS. FOR ALL AGE GROUPS FEWER WOMEN THAN MEN ARE FULLY TO BLAME IN ACCIDENT CAUSATION. IN CONSIDERING THE CAUSES OF ACCIDENTS, IT SHOULD BE RECOGNISED THAT CROSSING THE ROAD AND STEPPING OUT SUDDENLY FROM BEHIND OBJECTS WHICH OBSTRUCT THE VIEW, LEAD TO MOST ACCIDENTS IN THE GROUP FROM UNDER 6 TO UNDER 10 AGE. IN THE 10 TO 15 AGE GROUP THE NON OBSERVANCE OF RIGHT OF WAY TRAFFIC SIGNS AND INCORRECT TURNING OFF TO THE LEFT INTO ANOTHER STREET MAY BE REGARDED AS ADDITIONAL CAUSES. NO MAIN FACTOR PERTAINING TO CAUSE COULD BE DETERMINED IN THE CASE OF ADOLESCENTS. THE TIME OF DAY AT WHICH ACCIDENTS OCCURRED SHOWS THAT SCHOOL CHILDREN OFTEN HAD ACCIDENTS BETWEEN 7 AM AND 8 AM AND BETWEEN 12 NOON AND 7 PM, THAT IS, ON THE WAY TO AND FROM SCHOOL. THIS PARTICULAR RISK TO CHILDREN IS ALSO INDICATED BY THE FACT THAT FEWER CHILDREN ARE INVOLVED IN ACCIDENTS DURING SCHOOL HOLIDAYS.


A manufacturing method of versatility natural mineral processing material is provided to accelerate growth of animal . plant, to purify environment, to be harmless to human body and to contribute real life at cheap cost. A manufacturing method of natural mineral processing material comprises steps of: mixing natural mineral 50 99.9 weight% and basic material 0.1 50 weight% and obtaining a mixed compound; heating and fusing the mixed compound at 1300 to 1400°C and obtaining liquid melt; naturally cooling the liquid melt at room temperature for 24 to 48 hours; and pulverizing the cooled material. The natural mineral includes SiO2, Al2O3 and Fe2O3 as compulsory component and one or more components 0.1 to 5 weight% selected from a group consisting of CaO, MgO, K2O, Na2O, TiO2 and P2O5. The natural mineral is selected from a group consisting of yellow soil, clay, muscovitum, bentonite and zeolite.


Abstract : The importance of accurate typhoon forecasts to the island of Taiwan and the existing challenges in this area are reviewed by Wu and Kuo (1999). A particular area of emphasis is understanding the physical processes resulting from the interaction between typhoons and the Central Mountain Range, which runs across the center of the island. Wu and Kuo (1999) discuss much of the earlier research in this area, but additional work has continued to be done in the last decade with an increasing focus on the resulting precipitation distributions over the island. While idealized studies such as Lin et al. (2005) have been important in clarifying the basic theory of cyclone-terrain interaction, case studies of actual events continue to be necessary to apply these theoretical ideas to real storms. The island of Taiwan was located within the study area of the Tropical Cyclone Structure - 2008 (TCS08) experiment which was carried out in August and September of 2008 in the western North Pacific. During the course of the TCS08, two storms made landfall on Taiwan: Typhoon Sinlaku in mid-September and Typhoon Jangmi two weeks later. These storms were both distinguished by especially large maximum rainfall accumulations, particularly in the case of Sinlaku. In this study, we will examine the effect of the Taiwan terrain on the track and precipitation distribution of these two storms using real data numerical model simulations. We will also present preliminary model results from Typhoon Morakot which struck Taiwan a year after TCS08 and produced as much rainfall as Sinlaku and Jangmi combined.


The article is concerned with statistical analysis of the relationship between the ground level fine aerosol concentrations and the aerosol optical depth of the atmosphere. The aerosol characteristics measurements at two monitoring sites in the Middle Urals (Yekaterinburg city and the background region) combined with meteorological parameters and vegetation indices were used. Several linear models to estimate fine particulate matter concentrations using aerosol optical depth measurements and meteorological parameters are presented.


Scanning microscopy can be used to obtain crystallographic information about suboptical structures. By the same token, the x‐y‐z length scales of scanning microscopy can be brought into mutual consistency by measuring the angles between facets of crystallites of known habit.


Objective To assess the short-term prognosis in patients with tuberculous meningitis(TBM) and its influential factors. Methods The outcomes of improvement on discharge,or deterioration/death were taken as the index to analyze general clinical data,the parameters of laboratory and nuero-imaging examinations of the 105 TBM patients.And univariate and binary multivariate Logistic regression analyses were taken to determine the influential factors to prognosis of the patients. Results The univariate analysis showed that there were statistically significant differences between the improved group and deteriorated/death group in conscious level,blood white-cell count,and radiographic evidence of brain swelling(P0.05).The multivariate Logistic regression analysis showed that the decreased chloride levels of cerebrospinal fluid and decreased level of consciousness on admission were independently associated with the short-term poor outcome. Conclusion The patients with tuberculous meningitis who have decreased chloride levels of cerebrospinal fluid and decreased level of consciousness have poorer clinical prognosis.


BAM is a conserved molecular machine, the central component of which is BamA. Orthologues of BamA are found in all Gram‐negative bacteria, chloroplasts and mitochondria where it is required for the folding and insertion of β‐barrel containing integral outer membrane proteins (OMPs) into the outer membrane. BamA binds unfolded β‐barrel precursors via the five polypeptide transport‐associated (POTRA) domains at its N‐terminus. The C‐terminus of BamA folds into a β‐barrel domain, which tethers BamA to the outer membrane and is involved in OMP insertion. BamA orthologues are found in all Gram‐negative bacteria and appear to function in a species‐specific manner. Here we investigate the nature of this species‐specificity by examining whether chimeric Escherichia coli BamA fusion proteins, carrying either the β‐barrel or POTRA domains from various BamA orthologues, can functionally replace E. coli BamA. We demonstrate that the β‐barrel domains of many BamA orthologues are functionally interchangeable. We show that defects in the orthologous POTRA domains can be rescued by compensatory mutations within the β‐barrel. These data reveal that the POTRA and barrel domains must be precisely aligned to ensure efficient OMP insertion.


Objectives: To determine the efficacy of intravitreal aflibercept (IVA) in the patients with diabetic macular edema (DME) refractory to previous intravitreal ranibizumab (IVR) treatment. Materials and Methods: A total of 21 eyes of 21 patients who were switched to IVA therapy due to recalcitrant DME to prior IVR treatment were studied retrospectively. The visual and anatomical parameters at baseline, after IVR treatment and on month 6 after initial IVA injection were compared. The effect of DME type on the outcomes and the predictive factors were also evaluated by using a multiple linear regression model. Results: The mean number of IVR injections was 6.1±1.4 (5-9) before switching. The mean number of IVA injections after switching was 3.3±0.5 (3-5). The mean central macular thickness (CMT) was 426.3±91.7 μm at baseline and 417.6±80.8 μm after IVR injections. After switching to IVA the mean CMT was decreased to 285.7±46.8 μm (p<0.001). The best corrected visual acuity (BCVA) was 0.5±0.3 Logmar at baseline and 0.3±0.2 Logmar after IVR injections. After switching to IVA, the mean BCVA was improved to 0.16±0.15 Logmar (p<0.001). The patients with diffuse retinal thickening responded better to IVA injections than the patients with other DME subtypes regarding to CMT (p=0.044). However, BCVA improvement was limited in those patients. The number of IVA injections was a good predictor for final CMT and the DME subtype was a good predictor for BCVA. Conclusion: In patients with refractory DME to prior IVR injections, switching to IVA resulted in anatomical and visual improvement.


An equivalent model of Ge 0.05 Si 0.95 /Si rib waveguide is proposed. On the basis of this model,the effective refractive index of Ge 0.05 Si 0.95 /Si rib waveguide is calculated by means of numerical iteration which is of great significance for the design of rib waveguide.


The control of flow and heat transfer has recently been of great interest to engineering researchers in light of computational technology advances. Microjets are used as control solutions to avoid flow separation and increase heat transfer. The present study evaluates a microjet over a ramp at microjet velocity ratios (jet to inflow velocity) of = 1, 2, and 4 and heat flux ratios (heat flux to based heat flux) of = 1, 2, and 3 to examine the flow separation area and heat transfer improvement numerically. The numerical velocity and temperature gradients were compared to earlier numerical and experimental works. Then, the flow over the ramp was analyzed at the aforementioned microjet velocity and heat flux ratios. Moreover, streamlines, bed pressure, fluid temperature, and bed Nusselt number were evaluated. It was found that a microjet with the optimal velocity could not only diminish the separation bubble but also improve heat transfer. A rise in the velocity ratio from 2 to 4 led to a nearly 33% decrease in the separation bubble and an approximately 20% rise in the Nusselt number. In addition, the microjets enhanced heat transfer by up to 50%.


3D Observations of Positive Cloud-to-Ground Flashes Using Interferometer Sachiko Yoshihashi, Student Member, Zen-Ichirou Kawasaki, Member, Kenji Matsu-ura, Member (Osaka University), Yasuo Sonoi, Member (Kansai Electric Power Co., Inc) The field observations are conducted during winter thunderstorm. We obtained excellent data sets of pos itive CG flashe more than ten. Three-dimensional images of UHF radiation sources for positive CG flashes are shown. UHF radiation sources at leader progression stage show the tendency of concentration at constant altitude (2km, -5degrees) without any remarkable progression. On the other hand, after the return strokes the location of radiation sources proceeds very rapidly and penetrates into the thunderclouds horizontally. By applying the "Bi-directional leader concept", 3D location of positive CG flashes is interpreted. The UHF radiation intensity of the negative leader is about 15 dBm stronger than that of the positive leader. Therefore, in case of 3D location of positive CG flashes, we can see negative leader propagating into thunderclouds, and we do not see positive leader tip coming down to ground.


A process of forwarding data on a route from source to destination is termed as routing. This process of routing data from source node to destination node is accomplished by using its protocol. Routing protocols have the responsibility of movement of data through optimal path. As routing protocol play a vital role in infrastructure of computer network, more emphasis is given to routing protocols with security constraints. EIGRP is a distance vector routing protocol which is based on DUAL (Diffusing Update Algorithm), OSPF is an interior Dijkstra algorithm based protocol. OSPF is a link state interior gateway protocol. In first, proposed network topology has been configured with EIGRP and OSPF protocols with IPV6.Then routers are authenticated using MD5 and SHA algorithms. Performance is evaluated in terms of jitter and delay time. Average delay time and average jitter time are calculated for OSPF MD5, OSPF SHA, EIGRP MD5 and EIGRP SHA. It is observe that average delay time and average jitter time for OSPF MD5 is less then EIGRP MD5 and average delay time and average jitter time for OSPF SHA is less then EIGRP SHA.


Based on conventional Support Vector Machine(C-SVM) and through integrating fuzzy clustering technique and SVM algorithm, a multilevel binary tree classifier which is suitable for fault diagnosis task is presented and applied to fault diagnosis task of hydroturbine speed regulating system for the first time. Firstly, this method computes the clustering centers of each class by using fuzzy clustering technique and all clustering centers are divided into two successively. So, a binary tree is constructed. Then, it reconstructs SVM sub-classifier according to the clustering centers and the samples which belong to those clustering centers in each node of binary tree. The experimental results show that, in k-class fault diagnosis task, only k-1 SVM sub-classifiers needs to be constructed. In this way, the structure of the classifier is simplified and the unclassifiable region is avoided. Also, less memory is needed and a high rate of correct fault diagnosis is obtained.


Abstract: In previous reports, duration of initial ventilation exceeding 1 month almost always predicts non‐survival of babies with congenital myotonic dystrophy. However, a baby with this condition survived beyond infancy after 55 days' ventilation. We describe this case in detail, explain why the baby survived and highlight the importance of individualized assessment, in addition to applying general prognostic terms described in the literature.


The Spallation Neutron Source (SNS) under construction at the Oak Ridge National Laboratory (ORNL) will be the most important new neutron scattering facility in the United States. Neutron scattering instruments for the SNS will require large area detectors with fast response (< 1 microsecond), high efficiency over a wide range of neutron energies (0.1 to 10 eV), and low gamma ray sensitivity. We are currently developing area neutron detectors based on a combination of a 6LiF/ZnS(Ag) scintillator screen coupled to a wavelength-shifting fiber optic readout array. A 25 x 25 cm prototype detector is currently under development. Initial tests at the Intense Pulsed Neutron Source at the Argonne National Laboratory have demonstrated good imaging properties coupled with very low gamma ray sensitivity. The response time of this detector is approximately 1 microsecond. Details of the design and test results of the detector will be presented.


The advancement in last decade in electronics & communication, computer science and information technology domain has resulted in the new computing and communication era, known as Wireless Sensor Networks. The routing protocols differ on the basis of application and network architecture. With awareness is a compulsory design criterion, many new protocols have been specifically designed for routing, power management and data dissemination. Efficient routing in a sensor network requires that routing protocol must minimize network energy dissipation and maximize network lifetime. This paper analyses the lifetime of different routing protocols for wireless sensor networks.


This explanatory mixed methods study demonstrates the effects of collective thriving, measured at the work group level, on change adaptability and team performance. The results of the quantitative study show that collective thriving predicts change adaptability and team performance. Attunement is hypothesized to be a point of leverage to increase the state of collective thriving and as a team development opportunity. Attunement was found to have moderating effects on both relationships between collective thriving and change adaptability and collective thriving and team performance. The quantitative findings are explained with qualitative study, which looks more deeply into the effects of attunement by exploring how teams identify and sustain a state of thriving. The qualitative study also investigates characteristics of high and low thriving teams which furthers the understanding of collective thriving and the relationships between team thriving, change adaptability and team performance. As a result of th...


The aim of this experiment was to find out information on suitable trash fish for the growth and survival rate of mud crabs ( Scyla serrata ). The research was conducted in Marana Brackishwater pond research station of the Research Institute for Coastal Aquaculture, Maros, South Sulawesi for 28 days. Twelve  aquaria of 60 x 40 x 40 cm 3 were used in this experiment using Completely Randomized Design. Treatments tested were four differents species of trash fishes i.e. A; sibula   ( Sardinella sp), B; tembang  ( Clupea sp), C; Anchovy ( Stolephorus sp) and D; Tilapia  (Tilapia mosambica), each with three replications. Twentyfive pieces of crablets  of  5,9 + 0,2 mm in carapace width and 0,06 + 0,02 g in body weigth were stocked in each  aquarium.  Crablets  were then fed with trash fish with the dosage of 15% of total biomass per days  given twice a day. The results showed that the growth of crablets fed with tilapia was the best trash fish (P>0.05), among the treatments which were tested. The use of other fishes were not significantly different  (P>0.05) on the crablet growth.


The embodiment of the invention relates to the technical field of communication, and in particular relates to an intelligent television, an intelligent television peripheral device and an intelligent communication system, so as to improve the automation and intelligentization level of the establishing of match code connection between the intelligent television peripheral device and the intelligent television, and to shorten the time of the establishing of match code connection between the intelligent television peripheral device and the intelligent television. The intelligent television provided by the embodiment of the invention comprises a near field communication initiating chip which is used for detecting the intelligent television peripheral device through an antenna under the control of a microprocessor, sending a notification to the microprocessor when the peripheral device is detected, generating a signal which is of an NFC format and at least comprises the ID information of the intelligent television according to the ID information, which is fed back by the microprocessor, of the intelligent television, and sending the signal to the antenna, a microprocessor which is used for feeding back the ID information of the intelligent television to the near field communication initiating chip after receiving the notification, and the antenna which is used for sending the signal of the NFC format.


SETTING
Penitentiary system of Georgia.

OBJECTIVE
To determine the prevalence of resistance to second-line drugs among prisoners with pulmonary tuberculosis (PTB).

DESIGN
Retrospective evaluation of resistance to second-line drugs in tuberculosis (TB) patients treated from 2001 to 2003.

RESULTS
The overall observed prevalence of multidrug-resistant TB (MDR-TB) was 14.4% (39/270). The lowest resistance was found for ofloxacin (OFX), which was 2.2% (6/270) overall and 5.1% (2/39) among MDR patients. Isolates from four non-MDR patients who had never received anti-tuberculosis treatment were found to be resistant to OFX. Resistance to kanamycin and capreomycin occurred simultaneously only among MDR patients and was observed in 17/39 cases (43.6%). High rates of resistance to > or =2 second-line drugs (18/39, 46.2%) and > or =3 second-line drugs (10/39, 25.6%) were observed among all MDR-TB patients, reaching respectively 59.3% and 29.6% among previously treated MDR-TB cases. Only one patient was found to be resistant to four second-line drugs. No extensively drug-resistant TB (XDR-TB) according to the latest definition was detected.

CONCLUSION
Our findings reveal a serious threat to the TB control efforts in the study population.


The invention relates to a virtual resistor based circulation suppression control strategy of a modular multilevel converter (MMC), belonging to the technical field of power transmission. Aiming at the current situations that the running loss of the MMC is reduced, the resistance of a three-phase bridge arm is very small and the system stability is reduced after the additional arrangement of a circulation suppression device, the virtual resistor additional control strategy is added. By adding negative feedback control of bridge arm current, a transfer function of an MMC converter is changed, the resistance value of the bridge arm is equivalently increased, and thus, the stable running capability of the system and capacitor voltage automatically-balancing capability of an upper submodule and a low submodule are improved; and meanwhile, the virtual resistor in a control system is mapped to a primary system, no resistor exists in the primary system, the system loss of the MMC cannot be increased. In the core technical scheme, a resistance value R of the virtual resistor is set, a rated value is subtracted from an actual measurement value of the bridge arm current and then multiplied by R to be taken as a proportional negative feedback link, and finally, the proportional negative feedback link of the bridge arm current is additionally added to a circulation voltage generation link.


Background and Objectives Live cell-based assay (CBA) can detect acetylcholine receptors (AChRs) or muscle-specific tyrosine kinase (MuSK) antibodies (Abs) in a proportion of patients with radioimmunoassay (RIA)-double seronegative myasthenia gravis (dSN-MG). A commercial fixed CBA for AChR and MuSK Abs has recently become available; however, comparative studies on fixed and live CBAs are lacking. In this study, we compared the performance of fixed and live CBAs in patients with RIA-dSN MG and assessed their sensitivity in RIA-positive MG samples and their specificity. Methods AChR and MuSK Abs were tested in 292 serum samples from 2 Italian MG referral centers by live and fixed CBAs: 192 from patients with MG and 100 from controls. All samples had been previously assessed by RIA: 66 were AChR positive, 40 MuSK positive, and 86 dSN. All controls were negative. Two independent raters assessed the CBA results. Fixed and live CBAs were compared with the McNemar test; interrater and interlaboratory agreement were assessed with Cohen's kappa or interclass correlation coefficient (ICC), as appropriate. Results In 86 RIA-dSN samples, fixed CBA detected Abs in 10 cases (11.6%, 95% CI 5.7–20.3), whereas live CBA detected Abs in 16 (18.6%, 95% CI 11.0–28.5) (p = 0.0143). Of these sera, those positive by fixed CBA were also positive by live CBA. In addition, live CBA could detect MuSK Abs in 4 and AChR Abs in 2 samples that were negative by fixed CBA, providing an 8% (95% CI 2.9–16.6) further increase in the Ab detection rate. These results were confirmed by flow cytometry. In the RIA-positive cohort, the sensitivity for AChR Abs was 98.5% (95% CI 91.9%–99.9%) for fixed CBA and 100% (95% CI 94.6–100) for live CBA (p = 0.1573). For both assays, the sensitivity for MuSK Abs was 100% (95% CI 91.2–100), and the specificity was 100% (95% CI 96.4–100). Interrater agreement was almost perfect for live and fixed CBAs (Cohen's kappa 0.972 and 0.978, respectively), alike interlaboratory agreement. Interrater agreement for the CBA score ranged from good to excellent (ICC: 0.832–0.973). Discussion Fixed CBA represents a valuable alternative to RIA for AChR and MuSK Ab detection in patients with MG and could be considered as a first-step diagnostic test. Live CBA can be useful in the serologic evaluation of RIA- and fixed CBA-negative samples.


at which funds may be invested. This is roughly the same criterion as used in raising new capital. Oddly enough, and extremely important, the difference in the total pool of investable funds between Method B and Method C will be roughly equal to the market value of the shares given out when the options are exercised. Method B would result in the company buying the shares at the then-existing market price and selling them to persons exercising options at a lower price. For Company XYZ, this would mean buying shares at $85 a share and selling them at S5i a share. This would result in a net loss in investable funds to the corporation of $34 a share. On the other hand, Method C would result in selling additional shares to persons exercising options at S 51 a share. Therefore, the difference between the two methods equals $85


This article discussed the agglomeration and dispersion mechanism of ultrafine TiO2 powderHydrated Al2O3,SiO2 and Fe2O3 were used as modifiers for the surface treatment of TiO2 powderThe modified product was tested for the dispersity and wetting property,and analysed by electronic micrograph


Recently, lightweight material has been used widely in the field of automotive and electronic industries. However, some difficulties exists in characterizing the material, poor formability and abnormal stress-strain behavior such as Mg alloy sheet. In this paper, a new cyclic load tester, which can measure the stress-strain curves of thin sheet metals under non-monotonous condition such as tension /compression or compression /tension, was developed. Material tests including tension / compression/ tension or compression/tension/compression test are performed to aluminum and magnesium alloy sheets and construct a database of its material properties.


. The purpose of the study: to improve the results of treatment of patients with deep sternal infection, using the step-by-step principle of surgical tactics and a combination of vacuum-assisted closure therapy and bacteriophages. Materials and methods.The work is based on the materials of the examination and treatment of 88 patients with deep sternal wound infection from 2010 to 2019. Surgical management of patients was divided into three types, depending on the study group, the patient's condition and the nature of the course of postoperative sternomediastinitis: one-stage (applied retroactively), two-stage and three-stage approaches. The algorithm of complex treatment of deep sternal wound infection was improved by using vacuum-assisted hardware dressings in combination with local and oral application of bacteriophages at the stage of preparation of a poststernotomic wound for closure. Results. The proposed method allowed not only to reduce the duration of treatment of patients with postoperative sternomediastinitis, but also to reduce the frequency of relapses by 29.6% compared to the group using the «traditional» approach (p 1-3 <0.05) and by 10% compared to the group using monocomponent vacuum therapy (p 2-3 = 0.05). The mortality rate among the patients of the complex treatment group was two times lower than in the other groups and amounted to 5.0±0.1% (p<0.05). Conclusion. The proposed algorithm for the treatment of cardiac surgery patients with deep sternal wound infection is based on the use of local negative pressure on the wound process and the universality, evolutionary specificity of bacteriophages in the fight against bacterial pathogens, which contributes to a comprehensive increase in the effectiveness of treatment of patients with such a complication.


The paper attempts to examine the movement of sectoral Indices of India before, after and during the era of global financial crisis 2007-09. It is intended to examine the changing risk-return dynamics of Indian economy especially for the above discussed period. Changing risk-return dynamics will reveal the impact of global financial crisis on Indian economy and result thereof in the after crisis period. It covers daily return data of ten sectoral indices and S&P CNX Nifty for the period 2005 to 2011 which is further sub-divided into three periods; before crisis (April 2005 to November 2007), during crisis (December 2007 to June 2009) and after crisis (July 2009 to March 2011). Descriptive statistics, paired t-test and stepwise regression have been used for data analysis and presentation. The results indicate that the major impact is on sectors such as IT and Infra structure taking economy to restrictive growth run.


Early researchers into ICT in education, such as Papert (1980) and Turkle (1984), considered that students constructed reality from experience and prior knowledge. More recent theorists, such as Dede (2009), suggest that as technologies evolve, it will give rise to a set of constructs upon which the ICT capabilities based. In particular, the overarching element of applying social and ethical protocols. In this session you will see how you can link the virtual and real worlds of your students with the social and ethical protocols from the national curriculum and encourage positive engagement in both.


The purpose of this article is primarily methodological, aimed at develop-ing suitable methodologies for analyzing the perceptual structure of opposi-tion. The phenomenological internal structures of 37 opposite spatial di-mensions are discussed, based on data collected in two different experi-mental tasks. The data have been previously discussed in terms of non-fuzzy logic (Savardi, & Bianchi, 2000). This paper explores the potential applications of a fuzzy model for reanalyzing the data. The fuzzy struc-tures for the 37 spatial dimensions, which resulted from an indirect method of obtaining membership functions, are presented and discussed.


This report presents an evaluation of the Model 8000 Falling Weight Deflectometer (FWD) manufactured by Dynatest as to variability and repeatability over a nominal range from 1,500 to 24,000 pounds and several rigid pavement structures. For the tests performed in this study the FWD exhibited statistically satisfactory values of variability and repeatability. Data are presented illustrating insitu moduli of rigid pavement layers using FWD deflection measurements. These values are compared to values generated by other devices. A procedure and criteria are presented for evaluating the load transfer efficiency of joints in rigid pavements. A procedure and criteria are presented for detecting the presence of voids under the surface layer of rigid pavements.


In the hybrid excited switching flux permanent magnet (HESFPM) machine, the d-axis flux linkage can be adjusted by both the armature current and the dc field current. In order to produce high torque within a widen speed range, a voltage closed-loop feedback control strategy is proposed in this paper. The error between the feedback voltage and the maximum phase voltage is used to determine the operation region of flux weakening control and adjust the dc field current and d-axis current in the flux weakening region. The proposed method is verified by simulation results.


The purpose of this paper is to answer the following question: If all hyperplane sections through the origin of a convex body are"equal", is the convex body"equal"to the ball? The meaning of the notion"equal"will change in the course of this paper. Similarly, we are interested in the following problem: If all orthogonal projections of a convex body onto hyperplanes are"equal", is the convex body"equal"to the ball? Topology and convex geometry are deeply interrelated in the solution and understanding of these problems.


Introduction Arterial spin labelling (ASL) MRI [1] is increasingly being used to measure cerebral blood flow (CBF) non-invasively with good spatial and temporal resolution. However, it suffers from poor SNR and struggles to produce robust, reliable CBF estimates given the complexity of cerebral anatomy and the multifaceted nature of neuropathology. Understanding the complicated mechanisms underlying blood delivery and exchange will aid the development of an ASL CBF quantification model that can accurately characterize cerebral physiology. This will enable more reliable perfusion estimates over a broad range of flow values and will help reduce the potentially confounding effects of pathology. There is evidence that the transverse decay of brain tissue is bi-exponential due to a marked difference between the T2 of the intraand extracellular compartments [2, 3]. However the transverse decay of the ASL perfusion weighted signal has not yet been interpreted in this way to estimate the location of the labelled blood water that has exchanged into the tissue. In this study we acquire multi-echo ASL data with vascular crusher gradients (VCGs) (to eliminate any intravascular contribution) to estimate the proportion of the ASL perfusion-weighted signal originating from the intracellular and extracellular tissue space. In addition we acquire equivalent measurements without VCGs to estimate the proportion of the ASL signal originating from the vascular compartment. By taking measurements over a range of post-labelling delays (PLDs) and tagging durations (τ) we can follow the dynamic changes in these parameters as blood is delivered to the brain. In this way, we provide a novel insight into the time-course of blood delivery and exchange within cerebral tissue.


Response to Roger Inghams's Commentary: Seeing the Real Through the Eyes of the Ideal, Some Comments on Traeen et al. (1992) Account of Gender Differences in Norwegian Young People's Sexual Behaviour


A method to send a method An information to be multiplexed with the error-prone radio broadcast channel and system is provided. The method includes determining stream length information for at least one data stream is transmitted, and associating a system parameter message to the stream length information. Related stream length system includes information parameter message, the data streams are transmitted separately. This process, even in the case where even if one or more individual streams are received in error, to promote the process of de-multiplexing and stream data of individual streams. .FIELD 9


45 Neonatal alloimmune thrombocytopenia should be strongly suspected in cases of neonatal thrombocytopenia with no evidence of sepsis, systemic disease, or skeletal anomalies associated with thrombocytopenia, and where maternal idiopathic thrombocytopenic pupura has been excluded. We describe two cases with typical clinical presentations in which standard methods for detection of maternal antibodies gave negative results, and we show that empirical treatment with human platelet antigen 1a negative platelets yielded successful outcomes in both cases.


Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired stem cell disorder associated with periodic hemolytic events. This benign clonal condition is caused by the abnormal X-linked phosphatidylinositol glycan class A (PIGA) gene and has been associated with cytopenias and thrombosis. Recent improvements in PNH diagnostics relate to technical advances in flow cytometry (FCM), which can detect PNH cells at about 0.01% of total cells. Also, limitations of fluorescent inactivated aerolysin (FLAER) for measurement of the RBC clone have been recognized. Earlier methods involved immunological techniques associated with complement-mediated RBC lysis. These tests, including both Ham's acid hemolysis test (HT) and the sucrose lysis test (SLT), can detect PNH cells at <5% of total cells. These lytic techniques have been replaced by multi-color


This research is an attempt to document the investigation of the contribution of family climate in Special Education of a student diagnosed with autistic spectrum disorders. Our goal is to study the family relationships and the factors that affect them. We examine if the understanding of the problem of the parents affects family relationships, if the acceptance of autism facilitates the special education of the pupil and if the Targeted Individual Structured Integrated Training Special Education Program for pupils with Special Educational Needs supports parents in shaping positive family climate. The target group consists of children with Pervasive Developmental Disorders in Autism Spectrum (PDD-FA) and adults who come into contact with them. The manner and time of employment of the target group is identified with the practice, and student case study with Pervasive Developmental Disorders in Autism Spectrum (PDD-FA). The tools for the observations consist of the empirical observation of the student, Checklists Basic Skills, the Framework Curriculum Special Education Program, the observations on the general and specific learning difficulties, and the teacing plan (annual, monthly, weekly, daily curriculum). Furthermore, the experiment and the questionnaire were used. The survey participants were five parents, two couples with a child on the autism spectrum and a couple with a child without. The importance of positive family functioning and the factors that affect the support of children on the spectrum are investigated.


Clinical characteristics Rhabdoid tumor predisposition syndrome (RTPS) is characterized by a markedly increased risk of developing rhabdoid tumors – rare and highly aggressive malignant tumors occurring predominantly in infants and children younger than age three years. Rhabdoid tumors can occur in almost any anatomic location, commonly in the central nervous system (i.e., atypical teratoid/rhabdoid tumor [AT/RT]); more than 50% occur in the cerebellum. Other common locations include extracranial extrarenal malignant rhabdoid tumors (e.g., rhabdoid tumors of the head and neck, paravertebral muscles, liver, bladder, mediastinum, retroperitoneum, pelvis, and heart) (eMRT), rhabdoid tumor of the kidney (RTK), and possibly small-cell carcinoma of the ovary (hypercalcemic type). Individuals with RTPS typically present before age 12 months with synchronous tumors that exhibit aggressive clinical behavior. Diagnosis/testing The diagnosis of RTPS is established in a proband with a rhabdoid tumor and/or a family history of rhabdoid tumor and/or multiple SMARCA4- or SMARCB1-deficient tumors (synchronous or metachronous) and identification of a germline heterozygous pathogenic variant in SMARCA4 or SMARCB1 by molecular genetic testing. Management Treatment of manifestations: Due to the rarity of RTPS, standards for management are evolving. Most individuals are treated by intensive multimodal therapeutic strategies, according to institutional preference combining surgery, radiotherapy, and chemotherapy. Prevention of primary manifestations: Prophylactic bilateral oophorectomy may be discussed after childbearing. Prevention of secondary manifestations: Consider risk-reducing treatment strategies (e.g., postpone or replace radiotherapy with high-dose chemotherapy or proton beam therapy; targeted therapy used concomitantly with, or before, standard chemotherapy). Surveillance: From birth to age one year: From age one year to age four to five years: After age four years: Evaluation of relatives at risk: It is appropriate to evaluate apparently asymptomatic older and younger at-risk relatives of an affected individual in order to identify as early as possible those who would benefit from prompt initiation of screening, treatment, and preventive measures. Genetic counseling RTPS is inherited in an autosomal dominant manner. The vast majority of individuals diagnosed with RTPS have the disorder as the result of a de novo germline SMARCB1 pathogenic variant. Most reported individuals diagnosed with SMARCA4-related RTPS inherited a pathogenic variant from an unaffected parent. Each child of an individual with a germline SMARCA4 or SMARCB1 pathogenic variant has a 50% chance of inheriting the pathogenic variant. However, penetrance appears to be incomplete and the types of RTPS-related tumors can vary among different members of the same family. Prenatal diagnosis for pregnancies at increased risk is possible if the pathogenic variant in the family is known.


Several trials have found that AZT added little benefit when included in two drug regimens. Human tolerance to AZT and HIV's propensity for becoming resistant to AZT are major problems. AZT remains the most prescribed HIV therapy, particularly in combination with 3TC. A popular solution for patients failing or intolerant to AZT or AZT/3TC has been d4T/3TC. AZT is known to penetrate the blood/brain barrier, thus helping to prevent or treat AIDS-related dementia. Over time, however, studies show AZT/3TC and d4T/3TC were essentially equivalent and that both should be helpful for dementia. Another study using d4T/ddI showed reduction in viral loads by 80 to 90 percent at 24 weeks, accompanied by a CD4 rise of about 40, but with significant neurological adverse effects. Combining d4T/ddI with protease inhibitors presents problems, such as a complicated dosing schedule and harsh gastrointestinal side effects. Combining hydroxyurea with d4T/ddI appears to strengthen this combination's effects. One study showed that the combination of ddI and hydroxyurea was unable to prevent the emergence of mutations that confer ddI resistance; however, the mutants were still sensitive to standard doses of ddI in the presence of hydroxyurea. One other conference report presented results of a two-arm trial comparing DuPont Merck's new DMP 266 plus indinavir to indinavir alone for 24 weeks. At trial's end, viral loads were down 2.2 logs (99.4 percent) in the indinavir arm, and CD4 counts, initially averaging 224, were up about 100 cells in both groups. The results achieved with DMP 266/indinavir rival those achieved with indinavir plus AZT/3TC or any two nucleoside analogs. DMP 266 not only is potent, but is taken only once a day.


Measurements of the current expansion rate of the Universe, $H_0$, using standard candles, disagree with those derived from observations of the Cosmic Microwave Background (CMB). This discrepancy, known as the \emph{Hubble tension}, is substantial and suggests the possibility of revisions to the standard cosmological model (Cosmological constant $\Lambda$ and cold dark matter - LCDM). Dynamic dark energy (DE) models that introduce deviations in the expansion history relative to LCDM could potentially explain this tension. We used Type Ia supernovae (SNe) data to test a dynamic DE model consisting of an equation of state that varies linearly with the cosmological scale factor $a$. To evaluate this model, we developed a new statistic (the \ta\ statistic) used in conjunction with an optimization code that minimizes its value to obtain model parameters. The \ta\ statistic reduces bias errors (in comparison to the $\chi^2$ statistic) because it retains the sign of the residuals, which is meaningful in testing the dynamic DE model as the deviations in the expansion history introduced by this model act asymmetrically in redshift space. The DE model fits the SNe data reasonably well, but the available SNe data lacks the statistical power to discriminate between LCDM and alternative models. To further assess the model using CMB data, we computed the distance to the last scattering surface and compared the results with that derived from the \emph{Planck} observations. Although the simple dynamic DE model tested does not completely resolve the tension, it is not ruled out by the data and could still play a role alongside other physical effects.


[1] The book's main contents consist of: Preface, Introduction (by Gumperz), Plan of the Book, Part One ('Ethnographic Description and Explanation'), Part Two ('Discovering Structure in Speech'), Part Three ('Genesis, Maintenance, and Change of Linguistic Codes'), Appendix One ('Background Reading'), and Appendix Two ('Outline Guide for the Ethnographic Study of Speech Use', by Sherzer and Darnell). The individual chapters are as follows. Part One: 'Models of the interaction of language and social life' (Hymes), 'Culture patterning of speech behavior in Burundi' (Albert), ' "Struck by speech": the Yakan concept of litigation' (Frake), 'The strategy of Turkish boys' verbal dueling rhymes' (Dundes, Leach, and Ozkok), 'Signifying and marking: two AfroAmerican speech acts' (Mitchell-Kernan), 'Riddles: expressive models of interrogation' (Roberts and Forman). Part Two: 'On sociolinguistic rules: alternation and cooccurrence' (Ervine-Tripp), 'Context and alternation in Koya kinship terminology' (Tyler), 'Social context and semantic feature: the Russian pronominal usage' (Friedrich), 'Remarks on ethnomethodology' (Garfinkel), 'On the analyzability of stories by children' (Sacks), 'Sequencing in conversational openings' (Schegloff), 'A kinesiclinguistic exercise: the cigarette scene' (Birdwhistell), Part Three: 'Social meaning in linguistic structures: code-switching in Norway' (Blom and Gumperz), 'Domains and the relationship between microand macrosociolinguistics' (Fishman), 'Ethnic processes on the Pathan-Baluch boundary' (Barth), 'A sociolinguistic approach to socialization; with some reference to educability' (Bernstein), 'The stylistic significance of consonantal sandhi in Trukese and Ponapean' (Fischer), 'On the mechanism of linguistic change' (Labov). Each chapter is introduced by an editorial essay. There is a comprehensive Bibliography, Name Index, and Subject Index. The items by Dundes et al. Roberts and Forman, Barth, and Sherzer and Darnell do not find a place in this review; please note that no sort of assessment is thereby implied.


RESULTS OF CONSOLIDATED-UNDRAINED PLANE STRAIN ACTIVE AND PASSIVE TESTS ARE REPORTED ON K SUB ZERO CONSOLIDATED SAMPLES OF RESEDIMENTED BOSTON BLUE CLAY AT OVERCONSOLIDATION RATIOS (OCR) OF ONE, TWO, AND FOUR. THE PLANE STRAIN EQUIPMENT, DEVELOPED AT M.I.T., USES A SAMPLE WITH DIMENSIONS OF 3.5 X 3.5 X 1.4 INCHES. THE VERTICAL AND HORIZONTAL STRESSES CAN BE VARIED INDEPENDENTLY. THE MAGNITUDE OF THE CELL PRESSURE DURING CONSOLIDATION YIELDS VALUES OF K SUB ZERO, AND PRESSURE TRANSDUCERS IN THE FIXED END PLATENS YIELD VALUES OF K SUB ZERO AND INTERMEDIATE PRINCIPAL STRESS. THE APPARATUS GIVES RELIABLE STRESS--STRAIN DATA FOR ACTIVE TESTS; FOR PASSIVE TESTS THE DATA BECOME UNRELIABLE BEYOND 2--4% AXIAL STRAIN BECAUSE OF NECKING AND VARIOUS SOURCES OF "FRICTION." HOWEVER, A FAILURE CRITERION BASED ON THE MAXIMUM OBLIQUITY OF PRINCIPAL STRESSES GAVE FAIRLY RELIABLE UNDRAINED STRENGTH PARAMETERS FOR PASSIVE CONDITIONS. THE ACTIVE AND PASSIVE TEST DATA SHOW THAT BOSTON BLUE CLAY HAS HIGHLY ANISOTROPIC UNDRAINED STRENGTH PROPERTIES. FOR NORMALLY CONSOLIDATED CLAY, THE RATIO 0.5 (SIGMA 1 - SIGMA 3): SIGMA VC, WHERE SIGMA 1 AND 3 ARE MAJOR AND MINOR PRINCIPAL STRESSES, RESPECTIVELY, AND THEIR DIFFERENCE IS MAXIMUM; AND WHERE SIGMA VC IS VERTICAL CONSOLIDATION STRESS, IS 0.34 FOR THE ACTIVE AND 0.19 FOR THE PASSIVE CONDITION; THE CORRESPONDING RATIOS AT AN OCR OF FOUR ARE 0.95 AND 0.67. THESE STRENGTH RATIOS HAVE BEEN VERIFIED BY UNDRAINED MODEL FOOTING BEARING CAPACITY TESTS. A COMPARISON OF PLANE STRAIN AND TRIAXIAL TEST DATA SHOWS THAT UNDRAINED TRIAXIAL COMPRESSION TESTS AFTER K SUB ZERO CONSOLIDATION YIELD RESULTS VERY SIMILAR TO THOSE OBTAINED BY THE ACTIVE TESTS. HOWEVER, TRIAXIAL EXTENSION TESTS UNDER THE SAME CONDITIONS WILL UNDERESTIMATE THE UNDRAINED PASSIVE STRENGTH. /AUTHOR/


This study explores the application of Article 7, Item VIII of the Anticorruption Law (Law 12.846/2013), which considers the existence of integrity programs when imposing sanctions on companies that engage in harmful acts against the Public Administration. Using a descriptive and exploratory bibliographic research method, the study aims to investigate the effectiveness and validity of anti-corruption compliance programs. The study raises questions regarding the efficacy of compliance programs in preventing crimes against public administration, and the applicability of the mitigation provision in cases where companies adopt "false compliance." Although several states and municipalities have issued anti-corruption laws that require companies to adopt integrity programs, the current legislation does not provide definitive requirements for the implementation of compliance programs. Therefore, the study examines the problem of paper-based compliance or "false compliance," which may result in an artificial instrument and facilitate the transfer of information from top to bottom.
The study argues that compliance programs must not only ensure compliance with the law, but also develop policies and ethical cultures that are aimed at all members of the social organization. This approach aligns with the company's social function principle and ensures that compliance programs, especially those aimed at preventing crimes, are effective. The study concludes that it is necessary to implement a compliance program that complies with compliance resolutions to ensure that the mitigation provided for in the Anticorruption Law is effectively valid and applicable. Ultimately, this study highlights the importance of a robust and effective compliance program in preventing corrupt practices within organizations and promoting accountability among directors and administrators of legal entities.


Aim: To study the influence of atorvastatin on plasma nitric oxide(NO), calcitonin gene-related peptide (CGRP)and endothelin (ET) in patients with early stage of acute myocardial infarction(AMI) .Methods: A total of 48 patients with AMI were divided into two groups: rountine treatment group, rountine treatment plus atorvastatin group, and 24 normal controls were chosen as normal control; the plasma NO,CGRP, ET and TC,TG,LDL-C,HDL-C levels were observed before and after treatment.Results: The levels of NO, CGRP in patients with AMI were lower than those in normal control group (P0.01),and the level of ET was higher (P0.01), which were improved after treatment (P0.01). The improvement of NO,CGRP and ET in atorvastatin group was better than that in the rountine treatment group (P 0.05).Conclusion: Vascular endothelial function deterioration is observed in patients with AMI. Atorvastatin can improve vascular endothelial function in patients with AMI.


The aim of this project is to study the users emotional journey when they are using video on demand (VoD) applications. The methodology of user-centered design (ISO 9241-210) is applied in the case study of Yomvi. The context specifications and requirements are defined in order to develop deliverables such as personas and user journey map. Data collection is performed from a quantitative research of secondary sources and qualitative research from online surveys and semi-structured interviews. The results show a potential of improvement of the user experience through redesign of the application interaction, information architecture, navigation and generating adaptive covers for the contents.


In the present thesis, the construction, the operating principle and the dynamic
and steady-state models of induction and synchronous generators used in wind
energy systems are examined.
The induction generator (IG) models are derived in the arbitrary reference
frame, which can be easily transformed to any other reference frame. These
models are suitable for both squirrel-cage induction generators (SCIGs) and
doubly fed induction generator (DFIG).
The synchronous generator (SG) models are developed in the
synchronous reference frame, which is the most the convenient reference frame
for the analysis of synchronous generators. These models are applicable to both
wound rotor synchronous generators (WRSGs) and permanent-magnet
synchronous generators (PMSGs).
Case studies are provided to investigate the dynamic and steady-state
behavior of the generators.
Finally, the system analysis above is verified through extensive simulation
results.


This work presents the influence exerted by the bacterial inoculation of legumes and nitrogen-based fertilization of temporary pastures on the rate of atmospheric nitrogen fixation (BFN). The researches were carried out in an experimental display consisted of a bifactorial experience (A = bacterial inoculation; B = nitrogen doses), during a three-year period, by planting an association of Dactylis glomerata (60%) + Medicago sativa (40%) . The estimated amount of BFN was determined with the method of nitrogen balance with a reference crop. The results achieved showed that, by inoculating the legume within the temporary pasture association, we may obtain an increase of the BFN rate from 2.66 kg/1% alfalfa to 3.24 kg/1% alfalfa, respectively an estimated amount of 0.65 kg N fixed /day/ha, in the inoculated variant.


The distribution of single Stop Signal Reaction Times (SSRT) in the stop signal task (SST) has been modelled with two general methods: a nonparametric method by Hans Colonius (1990) and a Bayesian parametric method by Dora Matzke, Gordon Logan and colleagues (2013). These methods assume an equal impact of the preceding trial type (go/stop) in the SST trials on the SSRT distributional estimation without addressing the relaxed assumption. This study presents the required model by considering a two-state mixture model for the SSRT distribution. It then compares the Bayesian parametric single SSRT and mixture SSRT distributions in the usual stochastic order at the individual and the population level under ex-Gaussian (ExG) distributional format. It shows that compared to a single SSRT distribution, the mixture SSRT distribution is more varied, more positively skewed, more leptokurtic and larger in stochastic order. The size of the results' disparities also depends on the choice of weights in the mixture SSRT distribution. This study confirms that mixture SSRT indices as a constant or distribution are significantly larger than their single SSRT counterparts in the related order. This result offers a vital improvement in the SSRT estimations.


In bridge erection, a steel girder undergoing in-plane loading is commonly subjected to the interaction of several forces. Many previous studies have highlighted the effects of single in-plane loads on plate buckling but only a few works concentrated on the combined effects. For this reason, the stability of steel plates subjected to the combined action of patch loading, bending moment, and shear stress was studied through parametric analysis in this work. In particular, the effect of patch loading length combined with bending and shear stress was investigated. Other parameters like patch loading magnitude, panel aspect ratio, and plate slenderness have also been considered to characterize the plate stability. Through an intensive finite element method (FEM) analysis, new design equations have been defined to describe the influence of plate and load parameters on critical buckling loads of plates subjected to combined loads, with regard to plates subjected to patch loading. A comparison with the FEM results offers good accuracy, with a maximum deviation equal to 5%. To validate the analytical equations, a practical example is given.目 的通过深入的数值分析研究面内综合加载条件下钢板的临界屈曲荷载变化规律。创新点1.提出一个确定钢梁在平面荷载作用下的临界屈曲系数的新公式;2.通过与有限元分析结果对比以修正参数并获得解析公式的高精度。方 法1.采用有限元分析软件Strand 7 研究矩形钢板在节点荷载、 弯矩和剪应力综合作用下的弹性稳定性;2.针对节点荷载长度、 载荷大小、 板长宽比和长径比等参数分析对综合加载条件下的钢板稳定性的影响;3.借助一个实际的例子验证解析公式的有效性。结 论1.通过与有限元结果的比较, 解析公式均表现出较高的精度, 误差均在有限范围内且不受板几何形状的影响;2.节点荷载、 弯矩和剪应力的综合作用通过减小板临界抗屈曲性导致钢板的屈曲失效;3.-综合加载会导致临界抗屈曲性减小一半。


This is the first issue of Epigenetics, which is the first international periodical focusing on the newly emerging field of epigenetics and is the official journal of the DNA Methylation Society. Our goal is that Epigenetics will be the lead primary journal in the field of epigenetics and will provide a comprehensive view of epigenetic modification, which spans biological systems and diseases. This diversity of themes and comprehensive approach to epigenetics is reflected in the composition of our editorial board, which includes world-class leaders in the different fields of epigenetics. The editorial board guides the peer review process and the development of the vision of the journal. We encourage members of the epigenetics community to contact the editorial board members with suggestions and questions regarding potential new submissions to the journal. The journal will provide a forum where epigenetic approaches to a variety of medical and biological issues could be discussed and where the common basic principles of epigenetics spanning different systems could be revealed and shared. Although cancer has been the main focus of epigenetics in the last decade, recent data suggests that epigenetic plays a critical role in psychology andpsychopathology. It is being realized that normal behaviors such as maternal care and pathologies such as Schizophrenia and Alzheimer's might have an epigenetic basis. It is also becoming clear that nutrition and life experiences have epigenetic consequences. The increasing awareness of the potential role of epigenetic deregulation in disease has spawned the development of diagnostic and therapeutic approaches using epigenetics. Although the questions asked are diverse, the unifying hypothesis is epigenetics. The journal will emphasize scientific rigor but will at the same time promote and encourage open mindedness as well as provocative and novel hypotheses and approaches. The journal will provide a platform for developing unifying methodologies,hypotheses, experimental approaches and diagnostic agents and will serve as a meeting place for researchers from different systems such as general biology, plant biology, cancer biology, cancer therapeutics, epigenetic pharmacology, neurobiology and psychiatry who are unraveling the epigenetic facets of their specific fields of interest. We recognize that our first issue is just a first small step, but we hope that it will be leading to a great journal, which will serve as the flagship of the epigenetics field. The success of the journal depends on the continuous and unswerving support of the epigenetics community by submitting the best papers to the journal, by participation in the review process and the editorial process and by contribution of suggestions and ideas. Our first issue includes examples of each of the different areas, which we hope to see covered in the journal in the future. The issue starts with a meeting report of the Environmental Epigenomics conference held at Durham North Carolina in November 2005. This report points out the prospect that the environment sculpts our genomes through epigenetic markings and that some of these markings might be passed through the germ line. This emerging relationship between the environment and our epigenomes impacts on our understanding of the relative role of genetic heredity and environmental exposures in normal behavior and disease susceptibility. The key promise in an epigenetic understanding of human disease is its potential reversibility by therapeutic agents. Our two reviews discuss pharmacological and therapeutic approaches directed at the two components ofthe epigenome DNA methylation (Mund et al., pp. 7–13) and chromatin structure (Kim et al., pp. 14–23). Karimi et al. discuss a new method LUMA for quantification of global DNA methylation, and Baron et al. (pp. 55–60) discuss DNA methylation as a tool for cell typing. A new mode of Igf2r imprinting in opossum which does not involve DNA methylation is discussed by Weidman et al. (pp. 49–54) and Rivenbark et al. (pp. 32–44) show that not all gene targets of DNA methylation in breast cancer will contain a CpG island and they propose expansion of the current model for methylation-dependent regulation of gene expression to include genes lacking typical CpG islands. Thatcher and Lasalle (pp. 24–33) show the global effects that the methylated DNA binding protein Mecp2 has on histone acetylation and modification during postnatal neuronal maturation, a finding, which has interesting implications on our understanding of the MeCP2 deficiency Rett syndrome. Our small first fruits do give us a glimpse of the different facets of the field from DNA methylation to chromatin, from methods development to diagnostics and from the environment totherapeutics. We hope that with the support of the members of the epigenetics community we will be able to establish a journal, of which we all will be proud.


In this study, 40 genotypes of durum wheat (Triticum durum) originating from Iran and Azerbaijan Republic were evaluated in both water-stressed and well-watered environments in 3 years 2008 to 2011 cropping years. In each environment, the genotypes were evaluated using a randomized complete block design with three replications. From the grain yield data, drought tolerance indices comprising of stability tolerance index (STI), mean productivity (MP), geometric mean productivity (GMP), stress susceptibility index (SSI), tolerance index (TOL), yield index (YI) and yield stability index (YSI) were calculated for every genotype. The resulting data were analyzed as obtained from a randomized complete block design. Significant differences among genotypes were observed for all drought tolerance indices. High yield value in non-stress and stress environments was exhibited by genotypes '40 (4411.22 kg ha -1) and '32' (4256.34 kg ha -1) respectively. The maximum value of STI (1.07), MP (3642.11) and GMP (3590.85) indices was by genotype '35'. The highest value for YI (1.24) was from genotypes '39' and '21'. Correlation coefficients revealed that TOL, MP, GMP, STI, HM, and YI indices could effectively be used for screening of drought tolerant genotypes. Using MP, GMP, TOL, YI and STI indices, genotypes UPGMA classification was done and three clusters were established that is paralleled to biplot analysis results. According to results in this study, G10 and G35 were the most drought tolerant genotypes which were clustered as group A. We suggest that tolerance indices including MP, GMP and STI are suitable for durum wheat drought tolerant genotypes selection.

 Key words: Biplot, Triticum durum Desf., multivariate analysis, water-stressed condition, yield stability.


A new lift tensile anchor is designed on the basis of analyzing the problems of mechanical tubing anchor in China at present. This article introduces the structureworking principle and salient feature of this tensile anchor. Through the application of 35 wells in oil field, we have recognized it has the characteristics of novel and rational structure, easily installing and removing, enhancing pump efficiency and improving working situation in pump well. It has good effect, so we will popularize and apply it to pumping wells.


Various suggested paths for the reactor production of the longlived /sup 32/Si are compared. The reaction series /sup 31/P(n gamma )/sup 32/P(n;p )/sup 32/Si was found to be the most promising. Experiences from absolute activity measurements by means of Cherenkov radiation and yields from reactor neutron irradiations of phosphonns are presented. (GE)


To the Editor: Potti et al. (Aug. 10 issue)1 apply a metagene model to the profiling of non–small-cell lung cancer (NSCLC) and demonstrate superior performance in predicting tumor recurrence and survival, as compared with a clinical model. We believe that the impressively contrasting results could be partially due to the incompleteness of the clinical model the authors used. Classifying NSCLC into squamous-cell carcinoma and adenocarcinoma has not been predictive for prognosis in general. However, subtypes of adenocarcinoma — bronchioloalveolar carcinoma and mixed adenocarcinoma with a bronchioloalveolar component, which account for approximately 20% of cases of early-stage NSCLC — have a much better prognosis than do other subtypes.2 Potti et al. did not consider these adenocarcinoma subtypes. In addition, the literature3 and our recent work demonstrate that the histologic grade is a significant predictor of both tumor recurrence and survival,4 and there is a high correlation between histologic features and gene-expression profiles.5 Our work also shows that incorporating the adenocarcinoma subtype and histologic grade into clinical models would provide a prediction very similar to that of a well-validated, 50-gene panel for survival.


With the load growth of supervisory control and data acquisition(SCADA) system,traditional communication pattern can no longer meet the needs of systematic development.Multicast communication mode can effectively improve the data transmission efficiency and the network performance,but its transmission reliability is poor.Therefore,a reliable multicast scheme combining multicast and error control mechanism is presented,which makes error detection at intervals and conducts error recovery by multicast.Based on analyzing the communication characteristics of SCADA system,the error control mechanism and data transfer process of reliable multicast are expounded.


In the literature on seclusion, the incidence and duration of seclusion have been studied with relation to particular characteristics of the individual patient (age, gender, country of birth, length of stay and diagnosis), and results have frequently been contradictory. Other studies have examined the seclusion practices of a selected service or group of services, finding that external factors such as temporal variables, the nature and staffing of a service, the physical environment and the ward culture may affect seclusion use. There has been a relative paucity of quantitative data in the literature to determine the roles of these variables. In Victoria, an extensive amount of data is held by the Office of the Chief Psychiatrist, as all episodes of seclusion are required by law to be reported to the Chief Psychiatrist. This study is a detailed analysis of all reported seclusion episodes in Victorian adult services over the course of the year 1999-2000, critically examining patterns of seclusion use and identifying service-based, patient-based and temporal influences on seclusion. Overall, 13.1% of all admissions into public mental health services for the year included a seclusion episode at some stage, and the mean duration of a seclusion episode was 4.8 hours. These results reflect relatively more frequent seclusion episodes than in the UK but less frequent episodes than in the US, and seclusion episodes lasting for shorter time periods than reported in studies from either the US or the UK. The overall rate of seclusion varied significantly across the year and across the week, and the majority (82.4%) of seclusion episodes occurred in the first half of the admission. Seclusion was significantly both less frequent but more prolonged in rural centres, and significantly more common and prolonged in centres without a high-dependency unit. Secluded patients had significantly longer admissions than non-secluded patients, and convincing results were obtained linking an increase in seclusion incidence and duration with male gender, younger age and psychosis. Several diagnostic categories were negatively associated with the incidence of seclusion, in particular the diagnoses of major affective disorder, acute stress reaction, and anxiety disorder, and having no identifiable psychiatric diagnosis. There is wide scope for further investigation of associations with seclusion. Accurate data on the reasons for seclusion, temporal factors across the day for secluding or breaking seclusion, the composition of staff on the ward at the time of seclusion is required. Research is also needed into the efficacy of seclusion, and under what circumstances it may be best used.


Background A facial palsy is a cause of an aesthetical and functional problem. An operative technique used the most commonly in particular cases is a hypoglossalfacial anastomosis. However, a function of a tongue in these patients is usually not entirely preserved. Authors sought the solution for that neurological deficit, exploring the anatomical conditions to perform the anastomosis between the facial and the suboccipital nerve. Materials and methods The study was performed on the 5 cadavers (10 sides). In the first step, antromastoidectomy was performed. Next, incision was prolonged to the C2 level. The suboccipital nerve was microsurgically dissected. The facial nerve was transferred to the suboccipital nerve, where the anastomosis was performed. J Surg Res 2022; 5 (1): 51-63 DOI: 10.26502/jsr.10020201 Journal of Surgery and Research Vol. 5 No. 1 January 2022. [ISSN 2640-1002] 52 Results The anastomosis was possible in every case. The measurements were divided into 3 groups. The first group are three distances describing the extent of the antromastoidectomy: superior 22±0.7 mm, posterior 21±2.8 mm and anterior margin of procedure 28±4.2 mm. The second group were the topographical distances crucial for identification of the neural structures: between the styloid process and the tip of mastoid process 34±0.6 mm, from the stylomastoid foramen to the tip of mastoid process 18±0.3 mm, from stylomastoid foramen to the suboccipital nerve 34±0.6 mm. The last one were diameters of the nerves: suboccipital 2.5±0.7 mm and facial nerve 2.5±0.7 mm. Conclusions The study has revealed that it is possible to perform suboccipital-facial anastomosis. Nevertheless, the functional assessment has to be investigated in further studies.


Radar signatures of rain cells are investigated using multifrequency/multipolarization synthetic aperture radar (SAR) images acquired from the space shuttle Endeavour during the spaceborne imaging radar-C/X-band SAR (SIR-C/X-SAR) missions in April and October 1994. In SIR-C/X-SAR images, radar signatures of rain cells over the ocean usually consist of irregularly shaped bright and dark patches that strongly depend on radar frequency and polarization. The radar signatures of rain cells observed in SIR-C/X-SAR imagery of the ocean originate from (1) the scattering and attenuation of the microwaves by raindrops and ice particles in the atmosphere and (2) the modification of the sea surface roughness induced by the impact of raindrops and by wind gusts associated with rain cells. Raindrops impinging on the sea surface generate ring waves, which enhance the sea surface roughness, but they also generate turbulence in the upper water layer, which reduces the sea surface roughness. Depending on the radar wavelength, ocean areas struck by rain can have higher or lower normalized radar cross section (NRCS) than the surrounding rain-free area; in ocean areas where heavy rain is impinging on the sea surface, the X- and C-band NRCS is usually enhanced, and the L-band NRCS is reduced. From the phase difference between the horizontally and vertically copolarized signals, estimates of the rain rate are obtained. The present analysis shows further that the presently used wind speed retrieval algorithms for the scatterometers aboard the ERS and ADEOS satellites may yield biased wind fields if several rain cells lie within a scatterometer resolution cell.


Aim. To determine the expression level of angiogenesis markers VEGF and VEGFR-1 in different histological subtypes of benign and in anaplastic meningiomas. Materials and methods. 32 cases of meningiomas which were removed during neurosurgical operations were analyzed. We studied peculiarities of the expression of angiogenesis markers in benign and malignant brain meningiomas. Results. VEGF expression was observed in tumor cells as well as in endothelial cells in 38, 8% of all cases. Tumors with weak, focal expression and also with immunonegative areas comprised 22, 2% of investigated cases. Expression of VEGFR-1 in microvessel endothelial cells was present in 61, 1% of analysed cases. Conclusions.: 1. The expression level of VEGF significantly differs among various subtypes of benign meningiomas with the most intensive expression in transitional subtypes. 2. Fibroblastic subtypes of benign meningiomas are characterized by the least expression level of VEGF and VEGFR-1. 3. The relationship between the grade of meningiomas according to the WHO classification (2007) and the expression level of VEGF was not determined. Thus, the angiogenic potential depends upon the histological structure and does not depend on the degree of malignancy. 4. The expression level of VEGFR-1 doesn't significantly differ between benign and anaplastic meningiomas.


The paper discusses the concept and connotation of the professional guidance based on the insufficient professional guidance in the universities by raising the following proposals: establishing a great professional guiding concept, strengthening the environmental construction, building the all-round development of the students and the system of cultivating the students' competence of the profession with the 12 guides to promote the university professional guidance, which helps students have the ability and quality in their self-fulfillment and self-realization of their professional life so as to promote social harmony and happiness.


A thermostable glucoamylase from Aspergillus fumigatus was purified to homogeneity. It was a glycoprotein with 23% carbohydrate content and an apparent molecular mass of 42 kDa. The enzyme showed m...


Purpose
The purpose of this study was to examine factors that affect knowledge management at universities in Makassar, Indonesia.

Design/methodology/approach
This study used explanatory research to find the causal relationship between the variables in the model. The unit of analysis was students at four universities in Makassar. The four universities were Hasanuddin University, Makassar State University, Islamic State University of Alauddin Makassar and Polytechnic of Ujung Pandang. Sample technique for this study was determined by using the proportionate stratified sampling method with a total sample of 300 students. Data were collected by using questionnaires and interviews. The analysis method used to test the model was structural equation modeling.

Findings
The results show that organization culture has a positive and significant influence on motivation. Organization culture also has a positive and significant influence on knowledge assets. Technology has a positive and significant influence on knowledge assets but not on motivation. Moreover, organization culture, technology and motivation do not have a positive and significant influence on knowledge management. Knowledge assets have a positive and significant influence on knowledge management.

Originality/value
Originality of this paper shows that built the model of organization culture and technology on motivation, knowledge asset and knowledge management to know about its effect, methods and variables that used in this study have not been discussed in previous studies with the same purpose, method and same location.


• The Project Morpheus Liquid Oxygen (LOX)/Liquid Methane HD4-LT and HD5 demonstrated acoustic-coupled combustion instabilities during testing at Stennis Space Center (SSC).• The instabilities have two causes and signatures– Overchilled CH4 with high CH4 injection velocity causes a high-amplitude, 1T, 1R, 1T1R (and higher order R harmonics). This instability usually manifests during low-throttle startup conditions and can propagate through mainstage throttle-up. It has never been shown to start after mainstage throtte-up.– Warm LOX causes transient, self-limiting instabilities that appear as 1T-1L or 1R (with harmonics). These instabilities typically happen at ignition (or shortly thereafter) and dampen out once the LOX injector chills in.• Vehicle-HD4 tests at JSC typically only demonstrate low-amplitude transient tones near ignition, which are probably due to "warm" LOX type instabilities which always dampen• The explanation for the lack of vehicle-test instabilities are theories in work:– The vehicle tests demonstrate a faster fuel injector pressurization fill compared to SSC, and the vehicle tests also have a higher frequency, more quickly dampened start water hammer.• To protect for the possibility of instability occurrence on the Morpheus vehicle, a new high-speed redline cutoff system has been designed, tested, and installed.


[40028-33-9] C4H6N2O4S (MW 178.19)

InChI = 1S/C4H6N2O4S/c1-3-5-11(7,8)6-4(9-2)10-3/h1-2H3

InChIKey = GPIUOIUVZRSIBL-UHFFFAOYSA-N

(reagent for in situ generation of methyl N-sulfonylurethane; provides lower concentrations and higher reaction temperatures than direct formation)

Physical Data: mp 102–103 °C.

Preparative Method: reaction of Methoxycarbonylsulfamoyl Chloride with Sodium Hydride in acetonitrile1 leads to the title reagent 1.


Titanium-molybdenum carbide nickel cermets ((Ti, Mo)C-Ni) were produced using high energy milling and reactive sintering process. Compared to conventional TiC-NiMo cermet sintering the parameters for reactive sintered cermets vary since additional processes are present such as carbide synthesis. Therefore, it is essential to acquire information about the suitable sintering regime for reactive sintered cermets. One of the key parameters is the final sintering temperature when the liquid binder Ni forms the final matrix and vacancies inside the material are removed. The influence of the final sintering temperature is analyzed by scanning electron microscopy. Mechanical properties of the material are characterized by transverse rupture strength, hardness and fracture toughness. DOI: http://dx.doi.org/10.5755/j01.ms.21.3.7179


Circulating sperm antibodies have been traditionally quantified by measuring sperm agglutination (SAT) and immobilization (SIT) in serum. Recently an indirect immunobead assay (IBA) for detecting these antibodies in serum has been reported. Immunobeads coated with rabbit antibody to one of the three major immunoglobulins (IgG, IgM and IgA) are used. The procedure involves mixing a Hepes washed sample of normal donor sperm with the individual sera followed by centrifugation and incubation with each type of immunobead preparation and observed for evidence of binding. Sera from 40 patients previously tested with SAT and SIT were compared in four groups. There was a good correlation between IgG-IBA and SIT and a poor correlation between IgG-IBA and SAT. The class of immunoglobulin detected most frequently was IgG.


Percutaneous central venous lines are commonly used to establish long-term venous access in the care of premature infants. Misplacement of these catheters can occur and may lead to significant morbidity and mortality. Here we report a very-low-birth-weight premature infant whose percutaneous central venous line was inadvertently placed into the spinal epidural space. The anatomical basis of this complication as well as a comprehensive review of literature are provided.


Surface-enhanced Raman scattering (SERS) spectroscopy is now a well-established phenomenon, which has been thoroughly characterized in a variety of interfacial and colloidal environments. Although some quantitative aspects of the underlying enhancement mechanisms apparently remain unresolved, attention is now shifting towards application of SERS to explore phenomena of chemical, physical, biological and industrial significance. The goal of this review is to appreciate the industrial value of innovative SERS technique on the basis of our experience in development of new SERS-active substrates and in their biomedical and biotechnological applications. Examples of diverse SERS analytical applications as well as some very recent facilities, as SERS microprobe analysis, SERS fiber optics probes, FT-SERS spectroscopy, SERS detection for high-performance liquid chromatography, etc. , are also discussed.


Sorghum is a plant of a family of grasses and is still a family with rice, corn, and wheat. Sorghum grows a lot in the yard of Pasir Mulya residence house Banjaran District Bandung West Java. House wife in this village have not used much of this sorghum plant as food. The purpose of this training is to provide knowledge to the house wife about the benefits of sorghum as a cake-making material. The focus of this research is the process of empowering women through training and mentoring to good packaging, so that the house wife can have activities that produce and help the economy in the area. Data collection techniques used in this research are observation, interview and documentation. The data obtained were analyzed using data analysis technique. The results stated that the process of empowerment of house wife group through the training of cooking skills by way of prescribing, teaches the making of correct cookies and hygiene's, training the use of the right tools, the packaging process to produce a good product and worth selling. The results of sorghum-based cookies are expected to become a consumable gift from the Pasir Mulya.


The decline in oil production from the lower 48 states of the United States continued unabated in 1991 and brought it to a level comparable to 1948, the year M. King Hubbert first publicly presented his estimate for the ultimate oil resources of this region. Hubbert continued work in this area until his death in 1989. At the time of his death, John S. Herold, Inc had been providing assistance and support for several years on an update of his seminal work on domestic petroleum resources. In this context, we present an update of this resource base and employ Hubbert's logistic equation to solve for ultimate recovery and to derive a curve depicting the life cycle of production of oil and natural gas.


Pure hereditary spastic paraplegia (SPG) type 4 is the most common form of autosomal dominant hereditary SPG, a neurodegenerative disease characterized primarily by hyperreflexia and progressive spasticity of the lower limbs. It is caused by mutations in the gene encoding spastin, a member of the AAA family of ATPases. We have screened the spastin gene for mutations in 15 families consistent with linkage to the spastin gene locus, SPG4, and have identified 11 mutations, 10 of which are novel. Five of the mutations identified are in noninvariant splice-junction sequences. Reverse transcription–PCR analysis of mRNA from patients shows that each of these five mutations results in aberrant splicing. One mutation was found to be "leaky," or partially penetrant; that is, the mutant allele produced both mutant (skipped exon) and wild-type (full-length) transcripts. This phenomenon was reproduced in in vitro splicing experiments, with a minigene splicing-vector construct only in the context of the endogenous splice junctions flanking the splice junctions of the skipped exon. In the absence of endogenous splice junctions, only mutant transcript was detected. The existence of at least one leaky mutation suggests that relatively small differences in the level of wild-type spastin expression can have significant functional consequences. This may account, at least in part, for the wide ranges in age at onset, symptom severity, and rate of symptom progression that have been reported to occur both among and within families with SPG linked to SPG4. In addition, these results suggest caution in the interpretation of data solely obtained with minigene constructs to study the effects of sequence variation on splicing. The lack of full genomic sequence context in these constructs can mask important functional consequences of the mutation.


Objective:To improve clinical diagnostic ability for paraganglioma.Methods:CT scan was performed in 36 patients and MRI were performed in 21.CT and MRI findings in 37 cases (43 lesions) with pathologically-proved paraganglioma were retrospectively analyzed.Of 43 lesions,32 were adrenal pheochromocytoma, 8 were extra-adrenal paraganglioma and 1 was carotid body paraganglioma.Results:The largest diameters of adrenal pheochromocytoma and extra-adrenal paraganglioma were more than 5cm.Necrosis and cystic degeneration were common findings(23/43).CT findings were of middle density.The signal intensity on T_1WI was similar to that of hepatic parenchyma,while on T_2WI was marked hyper-intensity.Usually, the tumorous parenchyma showed strong enhancement.A case of carotid body paraganglioma showed uniform intensity,with no necrosis and cystic formation.The feature and degree of enhancement were similar to that of the carotid artery.Conclusion:The CT and MRI findings of paraganglioma carry certain characteristics.For most cases,a reliable diagnosis can be made when combined with clinical information.


In a note that appeared in JBL 90 (1971), 481—82, the writer proposed a reading and Interpretation of RS 24. 245, obv. 4—5, whence it emerged that Mt. Sapänu (OT har sapon/$aphon) was reckoned by the people of Ugarit (and presumably Canaan generally) äs the site of a cosmic tree "whose 'head' is in the firma[ment]" (*? · &tf?y[] · *$h ·)· Th Suggestion was further proferred that, unlike the reverse portion of the tablet, the obverse (or what is preserved of it) would seem to have äs its main subject not the storm-god Baal äs hitherto assumed but rather his deified mountain-home. The text äs a whole (i. e., obv. and rev.) is thus seen to be structured äs an upsidedown version of CTA 3 C (UT *nt) with which it also evidences literary connections. We now propose to amplify these suggestions within the framework of a detailed discussion of the text's obverse portion. We intend to shcrw, on the basis of both internal and comparative data, that the text is to be constructed äs a paean to the deified Weltberg, with an importtant bearing on a number of Ugaritological and Old Testament Problems·.


ALVARENGA, Renata Ribeiro. Energy values of concentrate feedstuffs determined with broilers and by prediction equations. 2009. 66 p. Dissertation (Master in Animal Science) – Lavras Federal University, Lavras, MG.* Two metabolism assays were conducted in the Poultry Production Sector of the Animal Science Department of Lavras Federal University (UFLA) in Lavras, MG, Brazil. The objective was determining the energy values of concentrate feedstuffs utilized for broilers and validating the elaborated prediction equation by using the meta-analysis principle to estimate by means of the chemical composition, the metabolizable energy of energy and protein feedstuffs. In the first experiment, the nitrogen-corrected apparent metabolizable energy (AMEn) of nine protein feeds (four samples of soybean meal, one of semi-whole soybean meal, one of extruded full fat soybean, one of texturized soybean protein, one of micronized full fat soybean and one of corn gluten meal) was determined and, in a second experiment, of nine energy feeds (two corn hybrids, pre-gelatinized corn, two samples of sorghum, corn grits, wheat meal, broken rice and rice bran) was determined. Also, the laboratory analyses for determination of chemical composition of the tested feedstuffs were performed, which were utilized in calculating AMEn by the proposed equations. The statistical analysis was made by the adjustment of simple linear regression equations of observed in vivo values on the estimated values by each equation. All the equations were efficient in estimating the AMEn values of the tested feedstuffs, though the specific equations for energy feedstuffs had overestimated slightly the values, with biases of 1.38 and 1.22%. It follows that the equations proposed by Nascimento (2007) can be utilized to estimate, in a satisfactory manner, the AMEn of protein and energy concentrate feedstuffs of plant origin utilized for broilers. The equations with the greatest number of variables showed lesser estimative-standard error. Nevertheless, the equation AMEn = 4101.33 + 56,28EE – 232.97ASH – 24.86NDF + 10.42A DF was the most applicable in the prediction of the energy values in the tested feedstuffs. Guidance Committee: Paulo Borges Rodrigues UFLA (Major Professor), Antonio Gilberto Bertechini – UFLA and Renato Ribeiro de Lima UFLA


Japan's opening-up of capital market is driven mainly by two forces: on one hand it is the post-war recovery and development of Japanese economy;on the other hand,it involves the external pressures coming from the US and OECD.This research identifies an omni-directional but restricted gradual opening-up pattern,which has a positive effect on JPY's stable transition towards free convertibility under the capital account.Considering the similarity between China and Japan,an in-depth analysis of the causes,experience and lessons of Japanese capital market opening-up may provide practical reference for China's capital market opening-up.


There has been rapidly growing demand of polymeric materials coming from different aspects of modern life because of the highly diverse physical and chemical properties of polymers. Polymer informatics is an interdisciplinary research field of polymer science, computer science, information science and machine learning that serves as a platform to exploit existing polymer data for efficient design of functional polymers. Despite many potential benefits of employing a data-driven approach to polymer design, there has been notable challenges of the development of polymer informatics attributed to the complex hierarchical structures of polymers, such as the lack of open databases and unified structural representation. In this study, we review and discuss the applications of machine learning on different aspects of the polymer design process through four perspectives: polymer databases, representation (descriptor) of polymers, predictive models for polymer properties, and polymer design strategy. We hope that this paper can serve as an entry point for researchers interested in the field of polymer informatics.


The comprehensive managements for environment play crucial roles in construction programming of ecological model zone,as well as the key duty.In this paper,comprehensive renovation for environment is regarded as the first prior situation in the construction or ecological model zones.It narrates the natural,social,economic and the present situation of the environment qualities in Jingxian County,also,putting forth the detail measures and applicable countermeasures about environmental comprehensive renovation in Jingxian County,such as adjusting industry structure and industry distribution,fathering water pollution,using solid castoff and protecting country entironment from the view of the specific items.


The rubber tree (Hevea brasiliensis) is grown in tropical regions and is the major source of natural rubber. Using traditional breeding approaches, the latex yield has increased by six-fold in last century. However, the underlying genetic basis of rubber yield improvement is largely unknown. Here we present a high-quality, chromosome-level genome sequence of the wild rubber tree, the first report on selection signatures and a genome-wide association study (GWAS) of its yield traits. Population genomic analysis revealed a moderate population divergence between the Wickham clones and wild accessions. Interestingly, it is suggestive that Hevea brasiliensis and six relatives of the Hevea genus might belong to the same species. The selective sweep analysis found 361 obvious signatures in the domesticated clones associated with 245 genes. In a fifteen years field trial, GWAS identified 155 marker-trait associations with latex yield, in which 326 candidate genes were found. Notably, six genes related to sugar transport and metabolism, and four genes related to ethylene biosynthesis and signaling are associated with latex yield. The homozygote frequencies of the causal non-synonymous SNPs have been greatly increased under selection, which may have contributed to the fast latex yield improvement during the short domestication history. Our study provides insights into the genetic basis of the latex yield trait, and has implications for genomic-assisted breeding by offering valuable resources in this new domesticated crop.


InP is among the few semiconducting materials with the potential for excellence in several applications, including solar energy conversion. Thin InP layers have been prepared by electrodeposition of In films on Ti substrates (ca. 2 mg/cm{sup 2} of In) and their annealing in PH{sub 3} flow. The obtained material, characterized by scanning electron microscopy-energy dispersive X-ray analysis and X-ray diffraction techniques, shows uneven substrate coverage but good crystallinity. Photoelectrochemical investigations in acidic polyiodide medium show significant n-type photoactivity for the samples prepared from a nominally pure In layer. A p-type photoactivity is obtained depositing a small amount of Zn on top of the In layer prior to annealing. Results are compared with those obtained preparing InP layers on Ti by a conventional metallorganic chemical vapor deposition technique.


Abstract The paper asks and answers the question "When does dominance of a particular strategy play a role in the search for evolutionary stable strategies?" The answer is much less obvious than would appear at first glance. When there is strict dominance of a pure strategy, it is clear that the dominated strategy should never be employed in any conflict. However, when the dominance is not strict it is less obvious that the strategy should not be used. The research was originally intended to clear up this grey area in the theory of evolutionary stable strategies, but it has turned out to be of more than simply academic interest. The result can be used, with varying degrees of success, to simplify the search procedure for these evolutionary stable strategies when a reward matrix is given.


Cite this Record Abbott, James T. (2001) "Houston Area Geoarcheology: A Framework for Archeological Investigation, Interpretation, and Cultural Resource Management in the Houston Highway District," Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State: Vol. 2001, Article 20. https://doi.org/ 10.21112/ita.2001.1.20 ISSN: 2475-9333 Available at: https://scholarworks.sfasu.edu/ita/vol2001/iss1/20


Abstract Investigation of the quality characteristics of Takju brewing mashes prepared with several different yeasts was carried out during the 42-day brewing process, including examination of titratable acidity, amino acid content, sugar contents, alcohol contents, pH, reducing sugar, yeast population, lactic acid bacteria, and sensory evaluation. Fermivin yielded the highest titratable acidity, while la parisienne had the lowest. Fermivin also had the highest value of amino acid content (14.33%), while other yeasts shows period tended to increase over exclude Instaferm and Song chun. The amount of sugars in instaferm (11.33 °Bx) and instaferm red (10.53 °Bx) were higher than those in La parisienne red and Song chun (9.57 °Bx). The alcohol contents of instaferm was the highest value (15.20%) while the alchol content of the other yeasts tended to increase the fementation period. Fermivin had the highest pH at 12 th day among the yeasts(4.02), Instaferm red had the lowest pH among the yeasts (3.87) while safbrew wb-06 had the highest reducing sugar content(117.60 mg/mL). Instaferm obtained the highest preference in the sensory evaluation for all items.Key words: Takju, yeast, qality


Purpose

The purpose of this study is to introduce the concept of big data and provide a comprehensive overview to readers to understand big data application framework in libraries.

Design/methodology/approach

The authors first used the text analysis and inductive analysis method to understand the concept of big data, summarize the challenges and opportunities of applying big data in libraries and further propose the big data application framework in libraries. Then they used questionnaire survey method to collect data from librarians to assess the feasibility of applying big data application framework in libraries.

Findings

The challenges of applying big data in libraries mainly include data accuracy, data reduction and compression, data confidentiality and security and big data processing system and technology. The opportunities of applying big data in libraries mainly include enrich the library database, enhance the skills of librarians, promote interlibrary loan service and provide personalized knowledge service. Big data application framework in libraries can be considered from five dimensions: human resource, literature resource, technology support, service innovation and infrastructure construction. Most libraries think that the big data application framework is feasible and tend to apply big data application framework. The main obstacles to prevent them from applying big data application framework is the human resource and information technology level.

Originality/value

This research offers several implications and practical solutions for libraries to apply big data application framework.