Iterative hard thresholding (IHT) and compressive sampling matching pursuit (CoSaMP) are two types of mainstream compressed sensing algorithms using hard thresholding operators for signal recovery and approximation. The guaranteed performance for signal recovery via these algorithms has mainly been analyzed under the condition that the restricted isometry constant of a sensing matrix, denoted by $ \delta_K$ (where $K$ is an integer number), is smaller than a certain threshold value in the interval $(0,1).$ The condition $ \delta_{K}< \delta^*$ for some constant $ \delta^* \leq 1 $ ensuring the success of signal recovery with a specific algorithm is called the restricted-isometry-property-based (RIP-based) bound for guaranteed performance of the algorithm. At the moment, the best known RIP-based bound for the guaranteed recovery of $k$-sparse signals via IHT is $\delta_{3k}< 1/\sqrt{3}\approx 0.5774,$ and the bound for guaranteed recovery via CoSaMP is $\delta_{4k} < 0.4782. $ A fundamental question in this area is whether such theoretical results can be further improved. The purpose of this paper is to affirmatively answer this question and rigorously show that the RIP-based bounds for guaranteed performance of IHT can be significantly improved to $ \delta_{3k} < (\sqrt{5}-1)/2 \approx 0.618, $ and the bound for CoSaMP can be improved and pushed to $ \delta_{4k}< 0.5102. $ These improvements are achieved through a deep property of the hard thresholding operator.


This paper shows the details of measurement of the Acoustic Transmission Loss evaluation with circular inlet and tail pipe with nozzle shaped muffler configuration. This configuration analyzed by using Finite element Analysis (FEA). For these purpose the evaluation of transmission loss of different nozzle shape of tail pipe has been simulated by keeping constant volume of Expansion chamber. Also the design validation has been done with the existing results with same dimension to prove the compatibility of acoustical simulation. To observe the effect of transmission loss of circular cross-section expansion chamber with introduction of various nozzle shape tail pipe at by analyzing in FEA Acoustic Module. After the observation the results are compared in order to observe the effect of introduction of nozzle shape outlet in muffler.


Renewable energy sources (RES) have significant potential to contribute to the economic, social and environmental energy sustainability of small islands. They improve access to energy for most of the population, they also reduce emissions of local and global pollutants and they may create local socioeconomic development opportunities. The aim of this paper is to provide a review of the theoretical and empirical literature on the contribution of RES to the energy sustainability of islands, focusing on the main results and the methodologies used. Papers are classified according to their coverage of the three dimensions of the triangular approach to sustainability (economic, environmental and social). The review also takes into account whether and how the procedural sustainability has been tackled in those papers. It is acknowledged that although several topics have been covered by the existing literature, there are promising avenues for future research on several fronts, both thematic and methodological.


This thesis provides an ethnography of the final year at an emerging middleclass private high school in the Northeast of Brazil. I draw on 15 months of fieldwork, including participant observation in the classroom wherein I followed students whilst they prepared for vestibular (the university entrance exam). Students' movements through Fortaleza, one of the world's most unequal cities, produced knowledge about the kind of person that one could and should be in the future. Private schooling appeared to provide a route for students to realise that metaphorical (and perhaps physical) movement. Vestibular served as a sort of rite of passage that could transform (emerging middle-class) youth into (middle-class) adults. Students and teachers characterised vestibular as a luta (fight) that could be won with enough training, flexibility and commitment. Good or high self-esteem was needed to overcome laziness and endure this luta and, thus, teachers and students worked on producing better self-esteem through affective work. Dreams (aspirations for the future) also played a critical role: the school encouraged students to engage in time work, to imagine appropriate future(s) into which students could channel their energies in the present. This version of individual power differed from the political and economic power structures portrayed in the classroom. Students grew indignant as, through curriculum and pedagogy, they came to understand that they were oppressed and that Brazil was underdeveloped and not quite modern. The university entrance exam served as a national meritocratic ritual that portrayed Brazil as becoming modern with governable and governing citizens. Students resisted these assertions and/but their cynicisms belied hope for better imagined futures. Using the classroom as container, this thesis presents a portrait of people and ideas in formation during a post-Lula era.


In this paper, we examine the demographic transition and its effect on economic growth using a cross-country data. We use a threshold regression model to verify the transition and to confirm whether the demographic transitions are compressed or not in developing countries. We found out that in general, the demographic transitions, including the decreasing birth and death rate, in developing countries start in an earlier development stage compared to the demographic transitions in developed countries. These results suggest that the aging population and the decreasing working-age fraction in developing countries can also start in an earlier development stage than the experiences of developed countries and that the demographic gift in developing countries can also be lost in an early stage.


This study aims to describe the information structure on newspaper headlines of the Bahasa Indonesia (bI) and the English (En)based on a Contrastive Linguistics. The information structure defined as a presentation of theme (old information) and rheme (new information). The data collected by observation method from two reputable sources, namely "The Jakarta Post" and "Kompas". The analysis conducted on three stages, i.e. data reduction, data analysis, and data interpretation. The results showed two focuses of description. First, generally, the newspaper headlines of the Bahasa Indonesia and the English had an information structure. The information structure constructed from the use of grammatical unit, i.e. words, phrases, and clauses. Second, specifically, there were three differences, namely (a) the patterns of information structure, (b) the types of theme, and (c) the types of rheme. For further analysis, it is important to use the approach of Cognitive Linguistics, for example, in order to identify the reason of speaker of the Bahasa Indonesia and the English when constructing and using the kind of headlines.


In 1952, the West African nation of Ghana, recently having freed itself from British imperialism, set out on a project of radical economic reconstruction unmatched anywhere on the continent in scope and ambition. Having attained political independence with the creation of a sovereign parliament and executive office, the Convention People's Party under the leadership of Kwame Nkrumah drew up extensive plans for ensuring the conditions necessary for real, not just on-paper, independence.


Puzzling problems of understanding,concept,thinking and method,etc,exist widely in medical and health institutions in promoting performance appraisal.Faced with the complicated situation and unprecedented challenges,the creative development of performance appraisal is the focusing point through linking theories with practice,with clear concept,thinking and method.These aspects are discussed.


A method for charging a battery, including: determining a final state of charge and a final temperature of the battery; and calculating charging power and/or cooling power required to reach the two final values within a minimum amount of time.


The present article describes the use of computational models to perform quantitative assessment of the environmental effects over the design period to ensure reliable operation of transport facilities, built with traditional materials. The peculiarities of forming moisture accumulation in road pavement materials and subgrade are given, as well as the climatic factors, which have an important role in change of the material properties of pavement.


Flash light due to photographing widely appears in video sequences especially in those obtained from news interviews, conferences and sports matches. When a flash picture is encoded, the intensity changes drastically and non-uniformly so that motion estimation can not find a well-matching block in reference pictures. Accordingly, much more bits are generated than the neighboring non-flash pictures. In this paper, a novel flash picture coding method which represents a new concept of video coding is proposed. Based on human vision system (HVS) property, rather than encoding the original flash picture, it encodes an artificial flash picture which is made up of an artificial non-flash (or de-flashed) picture and some parameters for flash effect modeling. Experiments show the proposed flash picture coding method greatly reduces the coded bits of the flash picture while still provides a competitive subjective quality.


In this paper, a method for estimating induction motor's rotor speed is proposed. The proposed rotor speed estimation method is based on model reference adaptive identification theory. By applying the proposed method, the induction motor control system can estimate the rotor speed of the induction motor precisely. To improve the rotor speed estimation performance of the system, one input filter and one output filter are introduced into the speed sensorless control system. The introduced input filter and output filter enhance the estimation accuracy and improve the reliability and robustness of the system. The speed sensorless control system based on proposed method was built with Simulink blocks in Matlab platform. The simulation results indicate that the proposed method can operate stably in whole range of speed with preferable identification precision of the rotor speed.


The main goal of this thesis, named Support of classical teaching using virtual classes and the Google Classroom environment, is to explain the options for implementation of Google Classroom into education. In the theoretical part the thesis aims to general information about e-learning and defines this term. Thesis also deals with the LMS and presents general information and some of these systems. The first chapter of the practical part describes user interface of Google Classroom and implementation of this service to education at high school. The description of the user interface can also be used as a brief manual that can help teachers to create a fully-featured course for any subject. Another practical output is creation of materials for teaching and studying on selected topics, which are used for education in the subject of information technologies. In the last part of the thesis, the results are verified by questionnaire survey which is based on appointed hypotheses.


In this paper, the characteristics of versatile base isolation methods, the analysis models of base isolation systems in common use and the hysteresis profile of isolation layers were summarized. The current design methods of base isolation structure in home and foreign were reviewed. The subjects of further studies were discussed and two research directions were pointed out.


Cell-wall thickening, rather than starch accumulation, leads to a decrease in mesophyll conductance after a reduction in the sink–source ratio in soybean and French bean. It has been argued that accumulation of nonstructural carbohydrates triggers a decrease in Rubisco content, which downregulates photosynthesis. However, a decrease in the sink–source ratio in several plant species leads to a decrease in photosynthesis and increases in both structural and nonstructural carbohydrate content. Here, we tested whether increases in cell-wall materials, rather than starch content, impact directly on photosynthesis by decreasing mesophyll conductance. We measured various morphological, anatomical, and physiological traits in primary leaves of soybean (Glycine max) and French bean (Phaseolus vulgaris) grown under high- or low-nitrogen conditions. We removed other leaves 2 weeks after sowing to decrease the sink–source ratio and conducted measurements 0, 1, and 2 weeks after defoliation.


Summary
Rape has been criminalized for a long time, but the meaning and intention has been shifted. During the end of 1900th century the primary intention was to enforce the honour of the family, particularly that of the man. Not until 1965 rape became criminalized within marriage, as the sexual integrity of women came into focus. Subsequently the sexual integrity was enhanced by expanding 6 chapter 1 § 2 st. BrB to hold even the cases when a person is in a helpless situation. Further on the same paragraph was expanded, only eight years later, to even cover persons in an especially vulnerable situation. Through this the legislator's intention was for all to have an adequate protection against sexual actions. At the same time, there was a discussion if a law based on consent should replace the law concerning rapes. That would mean that the requirement of constraint or exploitation was replaced by insufficient consent.
 The promoters for a law based on consent propose that the sexual integrity would be given a stronger protection by making it clear that sexual acts require consent from both parts. Focus would be against the suspect to investigate whether of not he made sure that there was consent. Further on it would also be a natural next step of the progress of law. Some even say that Sweden are obliged to introduce a law based on consent not to breach ECHR. The opposition against a law based on consent find difficulties with defining consent; how to make it legally valid. It would also induce difficulties with evidence. Moreover more focus than today would be on the acts of the victim, how the non-consent was shown. The purpose of this thesis has been to investigate whether or not a law based on consent would contribute something to law we have today. I have reached the conclusion that a law based on consent should institutes as a complement for today's law, to assure adequate protection in the field.


In recent days, the data are transformed in the form of multimedia data such as images, graphics, audio and video. Multimedia data require a huge amount of storage capacity and transmission bandwidth. Consequently, data compression is used for reducing the data redundancy and serves more storage of data. In this paper, addresses the problem (demerits) of the lossy compression of images. This proposed method is deals on SVD Power Method that overcomes the demerits of Python SVD function. In our experimental result shows superiority of proposed compression method over those of Python SVD function and some various compression techniques. In addition, the proposed method also provides different degrees of error flexibility, which give minimum of execution of time and a better image compression.


In this work we find numerical integration of a function by some approximations of the function using Bernstein polynomials, and we introduce a new fast method to approximate the value of a definite integral and we compare them.


This paper experimentally studies the gas flow structure in a longitudinal flow around a honeycomb surface with hexagonal cells of various sizes and depths. The measurements are carried out using the PIV system for the developed flow in a flat channel with the cross-section of 21 × 150 mm and the length of 1000 mm. The flow is visualized, and the velocity and turbulence components are measured in a smooth channel and in the presence of honeycomb surfaces. It has been shown that a boundary layer with high gradient of velocity and turbulent pulsations is formed near the honeycomb.


Abstract In Serbia, the first cases of HIV infection were reported in 1985, whereas antiretroviral (ARV) therapy has been in use since 1987. With this study we aimed to assess the occurrence and pattern of HIV resistance mutations among newly diagnosed patients in the period 2002–2011. The study prospectively included 181 adult patients. Genotypic HIV-1 drug resistance testing was performed and drug resistance was scored according to the 2009 WHO list for surveillance of drug resistance mutations (SDRMs). A bioinformatic approach was used to estimate the duration of infection by calculating the percentage of ambiguous basecalls per sequence, with a cutoff of 0.47% as the delimiter for recent infection. The overall prevalence of transmitted drug resistance (TDR) found in the study was 8.8% (16/181, 95% CI=5.5–13.8). Thirty-one percent of resistant samples contained multiple SDRMs. In particular, 5/16 patients with resistance carried viral strains with SDRMs to multiple ARV classes, hence one-third of resis...


As a special animal fiber, yak hair has many excellent properties, such as soft feeling, good elasticity, gentle glossy and excellent warmth retention performance, therefore, it has very high industrial value, and can be used as high-grade raw materials in the woolen industry. In this paper, the fineness, length, curl and surface morphology of Yak fiber were analyzed, and mechanical and tensile properties with the different conditions were discussed and compared.


INDEPENDENCE OF LEARNING IN ACCOUNTING CONTROL OF COSTS REVIEWED
FROM LEARNING CREATIVITY AND LEARNING MOTIVATION IN ACCOUNTING
EDUCATION STUDENTS OF MUHAMMADIYAH UNIVERSITY SURAKARTA 2015
FORCE
The purpose of this study are: 1) To determine the effect of learning creativity on learning
independence in cost control accounting for students of Accounting Education Surakarta
Muhammadiyah University Force 2015? 2 To determine the effect of learning motivation on
learning independence in cost control accounting for students of Accounting Education Surakarta
Muhammadiyah University Force 2015? 3 To determine the effect of learning creativity and
learning motivation on learning independence in cost control accounting for students of
Accounting Education Surakarta Muhammadiyah University of 2015This study is a type of
associative quantitative research with data obtained from numbers that aims to determine the
influence or relationship between two or more variables. The population in this study were all
students of the accounting education study program in 2015. The samples taken were 135 students
with simple random sampling. The required data is obtained through questionnaires and
documentation. The previous questionnaire was tested and tested for validity and tested for
reliability. Data analysis techniques used are multiple linear regression analysis, t test, F test, and
relative and effective donations.The results of regression analysis obtained the regression line
equation: Y = 10.033 + 0.301X1 + 0.471X2. Equations show that learning independence is
influenced by learning creativity and learning motivation. The conclusions taken are: 1) The
creativity of learning towards learning independence can be accepted. This is based on multiple
linear regression analysis (t test), it is known that t count> t table, 3.732> 1.960 and a significance
value <0.05, which is 0.000 with a relative contribution of 25% and an effective contribution of
10%. 2) Learning motivation for learning independence can be accepted. This is based on multiple
linear regression analysis (t test), it is known that t count> t table, which is 6.480> 1.960 and the
significance value is <0.05, which is 0.000 with a relative contribution of 75% and an effective
contribution of 29.9%. 3) Learning creativity and learning motivation towards learning
independence can be accepted. This is based on the analysis of variance of multiple linear
regression (F test), it is known that Fcount> Ftable, which is 27,889> 3,000 and a significance
value <0,05, that is 0,000. 4) The coefficient of determination (R2) of 0.399 indicates that the
magnitude of the effect of learning creativity and learning motivation on learning independence is
39.9%, while the rest is influenced by other variables.


Objective To explore the feasibility and safety of application of propofol anesthesia in patients undergoing fiberoptic bronchoscopy check-up.Methods The patients scheduled to undergo fiberoptic bronchoscopy check-up were divided into Group A in which the patients undertook surface anesthesia and Group B in which the patients undertook propofol anesthesia randomly.Vital signs,status of consciousness,body movements and awareness of the patients in anesthesia were observed.Results The patients in Group A showed clarity of consciousness,overmany body movements,steady SpO_2 but significant increase of heart rate and blood pressure.All of the patients compained of the uncomfortable experience of check-up after operation.Nevertheless,those in Group B showed loss of consciousness,less body movements,short-time decrease of SpO_2,heart rate and blood pressure but the magnitude of change limited in the range of clinic safty.No one compained of evident uncomfortable experience of check-up and operating awareness.Conclusion Application of propofol anesthesia in patients undergoing fiberoptic bronchoscopy check-up is safe and useful to diminish the uncomfortable feeling from operation.


The purpose of this paper is to investigate the impact of safety environment and task characteristics, job autonomy, and feedback associated with fatigue. Data were collected from 100 marine pilots in Turkey using questionnaires and the data analysis was done by using SPSS statistical program and hierarchical regression analysis. Three hypotheses were developed in order to determine the relationships between safety climate, job autonomy, feedback and fatigue. The results revealed that safety climate and autonomy have a significant negative impact on fatigue whereas feedback has no significant effect on fatigue. `This study makes several contributions to marine pilots' fatigue literature in terms of safety climate and task characteristics. Furthermore this study for the first time has measured the Turkish marine pilots' fatigue, safety, autonomy and feedback mechanisms.


The reaction of iron(III) chloride with heteropolytungstate [SiW 1 2 O 4 0 ] 4 - in acetate buffer gave the complex [Fe I I I 3(μ-O)(CH 3 COO) 6 (H 2 O) 3 ] 4 [SiW 1 2 O 4 0 ] . 19H 2 O. This complex was studied by single-crystal X-ray diffraction, IR and UV spectroscopy, and magnetochemical measurements.


The dynamical basis of transition-state theory is reviewed within the framework of classical mechanics with emphasis on the fundamental assumption on which the theory is based. Examples are presented showing that in a classical world transition-state theory is an excellent approximation in the threshold region. It is then shown how a quantum mechanical version of transition-state theory can be constructed which escapes the necessity of assuming separability. Results of calculations based on this theory are shown to be in good agreement with (exact) quantum mechanical scattering theory. (BLM)


This study found the effectiveness of music therapy on level of anxiety among patients diagnosed with cancer. Methodology: A quasiexperimental design was adopted for this study. Convenience sampling technique was used to select the samples from the selected hospital who met the inclusion criteria. The samples selected were conveniently assigned to the experimental group (30) and control group (30). The demographic data was collected using the demographic proforma and pre-test level of anxiety was assessed using the State Trait Anxiety Inventory scale for both experimental and control group. Music Therapy was provided for 3 days in two sessions, for experimental group samples along with the hospital interventions, while the control group samples underwent normal hospital intervention. Post-test level of anxiety was assessed using State Trait Anxiety Inventory scale for both the groups. Data was analysed using both descriptive and inferential statistics. Results: The findings of the study revealed that there was a constant decrease in mean anxiety scores from 66.27±2.86 (pre-test) to 39.27±5.112 (post-test) in the experimental group, which was in contrast to the mean anxiety score of the control group, which did not show much decrease. The mean anxiety scores of the control group pre-test was 64.6±3.2 and that of post-test was 63.00±2.9. To determine the effectiveness of music therapy on level of anxiety of the experimental group paired 't' test was used. The calculated 't'value was 31.93 greater than the table value 2.75 indicating music therapy was effective in reducing the anxiety among cancer patients. Unpaired 't' test was used for comparing the post-test change in level of anxiety among samples in the experimental group. The calculated 't' test value 23.9 of change in the anxiety score from pre-test assessment to post-test assessment was greater than the table value 2.39 this indicated that music therapy was effective in reducing anxiety. There was no significant association between level of anxiety and demographic performa. Conclusion: music therapy was effective in reducing anxiety among cancer patients.


Kale S. Trigger finger treatment & management. Medscape: Orthopaedic Surgery, 2016. http://emedicine.medscape.com/ article/1244693-treatment (accessed 30 March 2017). MacMahon PJ, Shelly MJ, Scholz D, Eustace SJ, Kavanagh EC. Injectable corticosteroid preparations: an embolic risk assessment by static and dynamic microscopic analysis. AJNR Am J Neuroradiol. 2011, 32: 1830–5. Shakeel H, Ahmad TS. Steroid injection versus NSAID injection for trigger finger: a comparative study of early outcomes. J Hand Surg Am. 2012, 37: 1319–23.


The current state of speech pedagogy does not fully reflect modern theory and research. This paper critically evaluates the best‐selling public speaking textbook in America, Stephen Lucas's The Art of Public Speaking, in terms of Kathleen Hall Jamieson's redefinition of "eloquence in the electronic age."; This paper explores how, if at all, the Lucas text takes account of the latest developments in rhetorical theory and changes in media technologies. Finally, the paper suggests how public speaking texts might uphold the classical virtues of eloquence while taking account of changes in the rhetorical environment.


Objective:To investigate establishing the multiple clinical processes model and pathological characteristics of EAE model,and to provide the experimental value for reseaching MS. Methods:The animal model was established in Wistar rat by immunization with complete Freund adjuvant and GPSCH, the pathological changes of EAE were studied with the aid of light microscopy. Results : We can divide the EAE into five types by pathological changes and clinical manifestation: acute EAE, relapsing-remitting EAE, persistent progress EAE,benigh form EAE and delitescence EAE. Every type mainly showed congestion and inflammatory cuff of small blood vessels,disintegration and disappear of myelin sheath and degeneration of neurons,especially in spinal cord. Conclusion:Multiple clinical processes on EAE model of Wistar rat were established for the first time.it is an ideal animal model in studying MS.


The kinetostatic accuracy of a manipulator depends not only on its configuration but also on its architecture. The focus of this paper is on the study of the relation between the aforementioned accuracy and the architecture of platform manipulators. It has been shown that some architectures can cause the associated Jacobian matrix to be either singular or very ill-conditioned in some regions of the workspace. These singular or ill-conditioned architectures can never be used in practice and hence, must be eliminated at the design stage. This is done using a design optimization approach. A design example is included to illustrate this approach.<<ETX>>


Sand-storage dams have proven to be a successful water harvesting method and potential solution to water and food security issues in semi-arid regions such as south east Kenya. This paper examines the microbiological quality of water both contained in the sand dam via test holes and abstracted from it through covered wells and scoop holes. In total, the values of thermotolerant coliform (TTC) concentration, turbidity, and pH are presented for 47 covered wells, 36 scoop holes, and 29 test holes, as well as the conductivity values in conductivity in 39 covered wells and 11 scoop holes. The water from test holes and covered wells was microbiologically of better quality than the scoop holes with median TTC levels of 0/100 mL and 159/100 mL respectively. However, the median values of turbidity for both scoop holes (20–30 NTU) and covered wells (5–10 NTU) exceed the World Health Organisation (WHO) guideline values. In addition the conductivity of water from 23% of scoop holes and 26% of covered wells is above the recommended WHO limit. This study also found that sanitary surveys are not a useful indicator of water quality in sand dams; however, they can identify areas in which sanitation and improvement of water sources are needed.


A novel navigation strategy is described that employs a time- of-flight sonar system to guide an autonomous vehicle through an unstructured environment composed of specular surfaces. Collisions are avoided by employing a scanning procedure that exploits the physics of sound propagation to detect objects. Physical models for the transducer beam and the reflection process are described. These models provide understanding about sonar ranging and are applied to deter mine the necessary scanning procedure for obstacle detection. In our environment, two types of echoes are observed: those reflected from surfaces and those diffracted from edges. Acoustic pulses reflected from oblique surfaces are not usually detected, and diffraction echoes are small and decrease with distance, making them difficult to detect. A scanning proce dure is developed to detect both types of obstacles. This pro cedure is employed to develop a navigation strategy that indicates the perceived obstacle-free region that guarantees that no collision will occur. The approach is illustrated with results produced by a vehicular robot equipped with a Polaroid sensor.


Advances in automation and genome sequence data will allow new protein structures to be produced faster than before. Structural biology has entered a new era -the era of structure genomics. It will accelerate the process of the structure determination of proteins and prompt research into the functions of closely related proteins. The study of structure genomics promises to bring about evolutions in all fields of biological sciences and other related areas, including medicine, agriculture, and the enzyme engineering.


Medical treatment decisions involve complex tradeoffs between the risks and benefits of various treatment options. The diversity of treatment options that patients can choose over time, and uncertainties in future health outcomes result in a difficult sequential decision making problem. Markov decision processes (MDPs) are commonly used to study medical treatment decisions; however, optimal policies obtained by solving MDPs may be affected by the uncertain nature of the model parameter estimates. In this article, we present a robust Markov decision process treatment model (RMDP-TM) with a controllable uncertainty set formulation for the transition probability matrices (TPMs) of the underlying Markov chain. We show that the RMDP-TM can overcome the common problem of over-conservativeness of the worst-case optimal policy obtained from the RMDP model with fixed uncertainty set formulations for TPMs. We present theoretical analysis to establish computationally efficient methods to solve the RMDP-TM and present its application to a medical treatment decision problem of optimizing the sequence and the start time to initiate medications for glycemic control for patients with type 2 diabetes.


For increasing failures of the 840D wheel and its incipient faults at present,the paper simulated the mechanical stresses and braking thermal stresses under different operation load cases with the FEM.According to the linear elastic fracture mechanics theory,the stress intensity factor was also studied.At last,associated with Forman fatigue crack propagation equation and the corresponding crack propagation threshold,the paper obtained the crack propagation characteristic and its propagation law at the web plate hole under different load cases and found the load condition which led to crack propagation.The result showed that the crack in the web plate hole was a typical fatigue crack,which initiated at the inner side of the web plate hole and propagated gradually.It was caused by the combined effects of the mechanical load and thermal load.Only the mechanical load can not lead to the crack initiation and propagation at the web plate hole.The superimposition of the grade braking and the mechanical load was the main operating conditions leading to cracking.It is very important to prevent fatigue failure,optimize wheel design and secure the safety of rolling stock.


osophy, vol. 62, (1984). 2 Jonathan Dancy, Introduction to Contemporary Epistemology (Oxford, Basil Blackwell, 1985) p.68. See also Jonathan Dancy and Ernest Sosa, A Companion to Epistemology (Oxford, Blackwell, 1992) entry on 'argument from analogy' p. 22; Norman Malcolm, Knowledge and Certainty (Ithaca and London, Cornell University Press, 1963) p.130; John Hospers, An Introduction to Philosophical Analysis Fourth edition (London, Routledge, 1997) p. 177; George Graham, Philosophy of Mind An Introduction, 2nd edn (Oxford, Blackwell, 1998) p. 52. 3 Andy Hamilton, 'Mill, phenomenalism and the self' in J. Skorupski (ed.) The Cambridge Companion to Mill (Cambridge, Cambridge University Press, 1998) p. 162. 4 J. S. Mill, An Examination of Sir William Hamilton's Philosophy, Collected Works of John Stuart Mill Volume IX edited by J. M. Robson (Toronto, University of Toronto Press, 1979) p. 205. MILL'S ARGUMENT FOR OTHER MINDS


This research is aimed to describe the situation of how teacher, proffesionalism is, toward the teaching learning processes of sport and health subject at senior high school I of Ketahun. This research used qualitative method, the data were collected by doing grand tour way, observation, interview and documentation study. The data were analyzed and reduced. The results show that sport and health teachers lack in desingining the lesson plan and giving evaluation to the learning proses. Keywords: professionalism, teachers, sport and health


Background: Ventricular dyssynchrony and its relationship to clinical outcomes is not well characterized in patients following Fontan palliation. Methods: Single-center retrospective analysis of cardiac magnetic resonance (CMR) imaging of patients with a Fontan circulation and age-matched healthy comparison cohort as controls. Feature tracking was performed on all slices of a ventricular short-axis cine stack. Circumferential and radial strain, strain rate, and displacement were measured; and multiple dyssynchrony metrics were calculated based on timing of these measurements (including standard deviation of time-to-peak, maximum opposing wall delay, and maximum base-to-apex delay). Primary endpoint was a composite measure including time to death or heart transplant listing (D/HTx); secondary outcomes were the presence of atrial or ventricular arrhythmias. Results: A total of 503 cases (15y; IQR 10, 21) and 42 controls (16y; IQR 11, 20) were analyzed. Compared to controls, Fontan patients had increased dyssynchrony metrics, longer QRS duration, larger ventricular volumes, and worse systolic function. Dyssynchrony metrics were higher in patients with right ventricular (RV) or mixed morphology compared to those with LV morphology. At median follow-up of 4.3 years, 11% had D/HTx, 7% ventricular arrhythmia, and 38% atrial arrhythmia. Multiple risk factors for D/HTx were identified, including RV morphology, ventricular dilation, dysfunction, QRS prolongation, and dyssynchrony. Ventricular dilation and RV morphology were independently associated with D/HTx; ventricular dilation and global circumferential strain were independently associated with ventricular and atrial arrhythmias. Conclusions: Mechanical dyssynchrony is highly prevalent in functional single ventricles palliated to the Fontan circulation and is more pronounced in hearts with RV or mixed ventricular morphology compared to those with LV morphology. Dyssynchrony is associated with death or need for heart transplantation and cardiac arrhythmias. These data add to the growing understanding regarding factors that can be used to risk-stratify patients with the Fontan circulation.


Humic substances (HS) represent ubiquitous products of dead
organic matter decomposition. In vivo experiments on fish have
shown induction of biotransformation enzyme CYP1A, a biomarker
of aryl hydrocarbon receptor (AhR) activation after exposure to
HS. Similarly to last referenced study, we have examined
interaction of HS with AhR, i.e. receptor that mediates toxic
effects of such compounds like PCDDs, PCDFs, PCBs (so called
dioxin-like compounds) and PAHs. Using in vitro bioassay, we
have found significant AhR-mediated activities of four out of
twelve HS tested. Applied bioassay is based on H4IIE-luc cells
(rat hepatoma) stably transfected with a luciferase reporter
gene under the control of dioxin-responsive element. In recent
contribution, we summarize our new findings on interaction of
AhR-active HS, being partial agonists of AhR, with full
agonists of AhR, e.g. 2,3,7,8-TCDD. Supposed ecological
consequences of our findings, and the scheduled research in the
field of HS will be discussed.


A 47-year-old man presented with several months history of increasingly severe abdominal discomfort and right testicular swelling. Physical examination revealed a huge right testicular and abdominal mass with signs of inferior vena caval obstruction. Palpable left supraclavicular adenopathy was also present. Radiological investigations revealed an abdominal mass measuring 12 cm in maximum diameter and causing right-sided hydronephrosis, (Fig. 1) multiple, bulky pulmonary metastases, (Fig. 2) and low volume mediastinal lymphadenopathy. Tumour markers were elevated with alpha feto protein (AFP) 2800 kU/l (0–10), human chorionic gonadotrophin (HCG) 138 IU/l (0–4) and lactate dehydrogenase (LDH) 2100 IU/l (220– 440). He was therefore considered to have intermediate prognosis, germ cell cancer [1]. An orchidectomy was performed and pathology showed a mixed tumour containing mature teratoma (MT) and embryonal carcinoma (Fig. 3). After retrograde stenting of the right kidney chemotherapy was commenced with four cycles of the BEP regimen (bleomycin, etoposide and cisplatin) [2]. Rapid-marker normalization was observed and the supraclavicular adenopathy resolved clinically to leave an area of indistinct thickening. Little change was seen in the radiological appearances in the abdomen at completion of chemotherapy, the lung metastases were however much improved and some were cavitating. Four months from initial presentation and 1 month from the completion of chemotherapy a laparotomy was performed, and a large


In this work we present the isotherms of water vapour sorption on composite "CaCl2 in silica gel" (SWS-1L) measured at T = 33.1, 49.0, 59.4 and 69.3 °C and vapour pressure P = 6-80 mbar. New analytical equation was suggested for approximation of the experimental data. It is based on the Polyani invariant principle and contains only 3 fitting coefficients. This equation provides good description of whole set of sorption data experimentally obtained so far and allows calculation of isotherms, isobars and isosters of water sorption on SWS-1L at any T and . It can be used for plotting and analysing thermodynamic cycles of adsorption heat pump utilizing SWS-1L. O H2


Using first-principles spin-polarized density functional theory, we carried out an analysis on the atomic structure, stability, energetics, and mechanical and electronic properties of single-layer structures of arsenene. These are buckled honeycomb, symmetric, and asymmetric washboard arsenene structures. Our analysis is extended to include layered three-dimensional crystalline phase of arsenic, as well as bilayer and trilayer structures to reveal dimensionality effects. The buckled honeycomb and symmetric washboard structures are shown to maintain their stability at high temperatures even when they are freestanding. As a manifestation of the confinement effect, the large fundamental band gap of single-layer phases decreases with increasing number of layers and eventually is closed. Concomitantly, lattice constants partially increase, while interlayer distances decrease. The effects of hybrid functional or self-energy corrections together with the spin-orbit coupling on the electronic structure of arsenene are crucial. The responses of direct and indirect band gaps to biaxial or uniaxial strain are rather complex and directional; while the fundamental band gap decreases and changes from indirect to direct with the biaxial strain applied to buckled arsenene, these effects are strongly directional for washboard arsenene. The width and the indirect/direct character of the band gap can be tuned by the number of layers, as well as by applied uniaxial/biaxial strain.


The uptake of thiamine in Escherichia coli was inhibited by thiamine phosphates. It was also demonstrated that the binding of thiamine to thiamine-binding protein, which is thought as a functional component in the transport system of thiamine, is markedly inhibited by thiamine phosphates.The possibility that thiamine and thiamine phosphates share a common transport system in Escherichia coli is discussed.


Objective:To study the relationship between obsessive-compulsive symptoms and personality of OCD patients and parental-rearing style.Methods:We adapt control case study to test 80 OCD children and 80 health control children with Leyton Obsessional Inventory(LOI;child version),Eysenck personality questionnaire(EPQ),EMBU(Own Memories of Parental Rearing Experiences in childhood),Correlations between parental child-rearing style,personality of OCD patients and obsessive-compulsive symptoms were also examined with Pearson Correlation Coefficients,Multiple linear regression analyses(stepwise method) were conducted to assess whether certain parental child-rearing patterns,personality of OCD patients predicted the presence of obsessive-compulsive symptom dimensions.Results: Neuroticism of OCD patients was significantly correlated with order/clean and general obsessions(P0.01).father's overprotection and mother's rejection were correlated with order/clean(P0.01),parents' rejection was significantly correlated with checking/repeating(P0.01).Conclusions: Adolescent obsessive-compulsive disorder occurs in a bad personality and parenting style,for obsessive-compulsive symptoms have certain forecast.


I would like to start with an image. It is a well-known image, perhaps overused, but effective nevertheless. Robert Nozick - the figure my paper concentrates upon - also uses it. I refer to Neurath's boat , the image according to which human beings are like sailors on the open sea, living forever in a boat tossed by the waves, devoid of any possibility to call at a port in order to avail of a dry-dock in which the inevitable damage brought about by the long sea voyage through the waves can be repaired. The sailors can do nothing by try to refis sails and mend broken planks while on the open sea, using just the tools and materials they have at hand. As is quite clear, the analogy is between the boat and uman knowledge, the waves and the experience given by the world, the dock and the foundations.


TERENCE LEE took his M.A. degree in psychology at Magdalene College, Cambridge, after war service with the R.A.F. and R.N. He was later appointed to a Rockefeller Research Fellowship and worked on urban neighborhood planning. He was awarded his Ph. D. in 1954. Since then he has been Research Fellow at the University of Exeter and Lecturer in Psychology, now Senior Lecturer, at the University of Dundee.


This paper presents a direct electrical measurement technique of mechanically vibrating single-walled carbon nanotubes (SWCNTs) actuated up to microwave L-Band frequency regime. Acoustic resonances of suspended SWCNTs are detected by means of inherent average strain (<ε>) dependent piezoresistive property of the nanotubes. A novel combination of capacitive drive and piezoresistive sensing eliminates the high-frequency measurement barrier associated with large contact resistance (RC) and capacitance (CC). We demonstrate via analytic modeling, with input parameters from previously fabricated semiconducting and small-gap semiconducting (SGS) CNTs that this detection mechanism is feasible to characterize resonating CNTs up to beyond Ultra High Frequency (UHF) range.


Chapter 25 covers the Truncated Hilbert Space Approach provides a very efficient numerical algorithm to study many properties of a perturbed conformal field theory defined on a finite geometry, typically an infinite cylinder of radius R. These include the masses of the various excitations, their number below threshold, the presence of false vacua and resonances, on-shell three-particle coupling, etc. The implementation of this approach does not depend on the integrability of the off-critical model and therefore it is a very useful tool to extend study to the entire scaling region around the critical point. This chapter discusses the basis of such an algorithm and provides some interesting applications thereof.


In this paper we study the analytic continuation of the Dyson-Schwinger equation into the entire complex p2 plane. It is shown that in the usual ladder approximation with a running coupling, there are two complex-conjugate branch points and one real branch point in the timelike region. The real branch point corresponds presumably to a physical mass for a quark; but it is removed by the addition of a so-called confinement term to the bare gluon propagator: with this extra term, there are at least three pairs of complex-conjugate branch points. The origin of these complex singularities is not yet clear.


The invention discloses a lithium sulfide/carbon composite nanometer material and a preparation method and application thereof. In a relatively typical embodiment, the method comprises the steps of fully mixing lithium sulfate and a carbon material precursor or a carbon material, and performing thermal treatment, wherein the thermal treatment condition comprises a temperature rising rate of 1-20 DEG C per minute, a constant temperature of 600 to 1000 DEG C for 2-12 hours in an inert atmosphere; and natural cooling of the material to a room temperature to acquire the lithium sulfide/carbon composite material. The invention provides a process for synthesizing the lithium sulfide/carbon nanocomposite material by reducing lithium sulfate with carbon, the process is simple and easy to operate, is high in controllability and low in cost, the raw materials are low in price and easy to get, moreover, the obtained product is the lithium sulfide/carbon nanocomposite material which is uniformly dispersed, has good performance and is controllable in morphology, the lithium sulfide/carbon nanocomposite material comprises a one-dimensional nanometer fiber, a two-dimensional nanosheet and the like, and the lithium sulfide/carbon nanocomposite material is high in conductivity and can be widely applied to an electrochemical energy storage device such as a lithium-sulfur battery.


Flight accident always takes place during approach-landing stage.This stage is a short time.The task is very important and the environment is complex.Air crew should be armed with excellent psychological quality and skilled driving technique.In order to ensure aviation safety,air crew must execute SOPs and enforce the ability of stable approach-landing and go-around.This paper focused on analyzing the factors affecting a stabilized approach and QAR data.In order to get the clustering coefficient which can assess safety of approach-landing stage,several parameters were assumed and a grey clustering model was established.This survey will help airlines to assess their fleets at the approach-landing stage with a quantitative method scientifically and it will improve flight safety really.


In Hungary the success of the far right is to a large extent due t o their effective exploitation of Roma issues. The first electoral success for Jobbik (Hungary's main far right party) came in the European elections in 2009; a year later they captured 16% of the vote in parliamentary elections in Hungary. At the same time a growing number of extra-parliamentary and sometimes paramilitary groups have also become active, some with close links to Jobbik. Support for the radical right doubled between 2002 and 2009. There are numerous factors behind the rapid rise and success of the far right in Hungary: mistrust toward democratic institutions, the state, and politics in general. Xenophobic attitudes rooted in the dominant definition of the Hungarian nation as mono-cultural and mono-ethnic can also be viewed as a determinant (but also as an effect) of the rise of the extreme right. More generally, economic decline, poor governance, interethnic tensions and the media's handling of the issue have contributed to strengthening the radical right. The mainstream political actors and the media have responded to Jobbik discourses on Roma, but often in ways that f ail to challenge some of the fundamental assumptions about the Roma .


We consider an exotic baryon (pentaquark) as a bound state of two-body systems composed of a baryon (nucleon) and a meson. We used a baryon-meson picture to reduce a complicated five-body problem to simple two-body problems. The homogeneous Lippmann-Schwinger integral equation is solved in configuration space by using one-pion exchange potential. We calculate the masses of pentaquarks and .


Fengzhi's poetry is characterized by life's contemplation,which introspect the limited life actively and is an activity to look for and point at the meaning.He develops the existentialism philosophy thought in his sonnets and gives it a new interpretation.This makes his sonnets become a model of the poetry with contemplation,whose unique value can not be replaced by other forms of poems in the history of Chinese modern poetry.


Regression testing is done to test the modified version of a software, however re-testing all test cases are very inefficient. Test Case Prioritization is one of the techniques used to overcome this problem. It prioritizes the test cases in the test suite by ordering them according to a desired objective goal like revealing faults earlier and has various approaches in performing it. One of them is model-based approach which utilizes the system model to make prioritization. The advantages of this approach are cheaper execution cost and lesser prioritization time compared to code-based prioritization. In this paper, we propose a model-based test case prioritization approach using extended finite state machine. The proposed approach will be based on several related existing approaches with an extra criterion of degree of code changes. The contribution of the proposed approach is it overcomes the identified limitations from the related works and improve the prioritization result.


Reflecting on the incisive years of the early 1920s, when he was already amongst the now celebrated group of writers gathered in Madrid, Guillen candidly informs us that he had wanted nothing more than to write a volume of poems; but he had not done so; and why? 'Because I never dared', he says. Guillen's hesitancy or caution is significant for it was to result in a first volume, Cantico (1928), that was relatively slim, composed entirely of short, intensely worked poems. His initial creative disposition may be described as guarded rather than precocious, but this is not to say, as some did, that he lacked inspiration; a criticism which has since been completely refuted by the pertinacious development of his life's work towards Aire nuestro.


In the experiment,biogas from dry fermented corn stalk which pretreated by green straw spirit,enzyme fungus,limewater and fast spoiled medicinal preparation in the same condition was made.The results showed that the biogas yield and the cellulose degradation was the highest when the corn stalk was pretreated by the enzyme fungus.And the biogas yield was 455.7 mL·g-1,the cellulose degradation was 56.9%.The experimental results systematically provided a theory foundation for the biogas making technology from corn stalk used into the engineering project.


Introduction: Measuring hunger and food insecurity has always been a challenge given the various tools available to provide estimates both at the macro (sufficiency in staple stock) and micro (household food security) levels. In the Philippines, estimates of food insecurity have been provided by the Food and Nutrition Research Institute (FNRI) starting 2001 using an adaptation of the Radimer/Cornell (1992) measures of hunger and food insecurity. The tool has been found to be reliable using the 2003 data extracted from the sixth National Nutrition Survey (NNS), Food Security module but was recommended for further exploratory factor analysis to test for efficiency of items. Methods: This study assessed the construct validity of the adapted Radimer/Cornell instrument for measuring household food insecurity using principal component analysis with varimax rotation based on the 2003 NNS data. Results: The results revealed the prevalence of food insecurity was higher at the mother's level (33.7%) compared to the child (21.0%), indicative of "managed process" or coping with food insecurity at the households. "Altered eating" emerged (factor 1) at the individual level of food insecurity, while "anxiety over quantity and quality of food" was (factor 2) at the household level, that explained 44.0% and 23.2% of the total variance, respectively. Thus, a high cumulative variance (67.2%) was generated for these two factors, implying sufficient variance was obtained to justify the derivation of these two factors from the dataset. Conclusion: The food security items in the adapted Radimer/Cornell instrument contained valid indicators for assessing food insecurity in Filipino households.


Natural biocidal products produced by plants are the major source of bioactive substances with strong pharmacological action and less cytotoxicity. The antibacterial activities of the alkaloid extracts of the leaves of Conocarpus lancifolius Engl. were bioassayed against certain plant and human pathogenic bacteria; Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Agrobacterium tumefaciens and Erwinia amylovora. The inhibition zones were ranged between 10-17 mm and the MICs were between 10 and >200 mu g/mL. Alkaloidal extract of C. lancifolius was active at all concentrations tested (5-200 mu g/mL) against the studied bacteria except E. amylovora. he result suggests the applications are also growth promotive and cost effective and non-hazardous in agro-ecosystem. Further work should be done to elucidate the valuable of C. lancifolius as a source of antibacterial for human and plant health.


Many observers despair of the prospects of encouraging intrinsic values among students in a world controlled by extrinsic rewards. The purpose of this article is to explore the question of whether intrinsic objectives such as subject-matter appreciation can coexist to any degree, let alone flourish, in the face of competing, if not higher, loyalties that involve a performance ethic based on scrambling for extrinsically oriented rewards, such as high grades, and avoiding punishments in the form of failing grades. Based on research conducted in ongoing classroom contexts at the college level, it is concluded that the pursuit of high grades and valuing what one is learning are not necessarily incompatible goals as long as certain conditions prevail. More specifically, students are more likely to value what they are learning and to enjoy the achievement process more: (a) when they are attaining their grade goals. (b) when what they are studying is of personal interest, and (c) when the dominant reasons for le...


Ⅰ. INTRODUCTIONAlthough many authors have investigated the structure of annealed metallic glass by means of small angle X-ray scattering (SAXS), there has been no report in which size distribution of the crystalline particle in aged metallic glass is determined. Determining size distribution of the crystalline particle will be beneficial to understanding the nucleation and growth process of the crystalline particle. In this note, size distribution of the crystalline parti-


of Cl in rat alveolar type I cells. Although Cl (cid:1) transport in fetal lung is important for fluid secretion and normal lung development, the role of Cl (cid:1) transport in adult lung is not well understood. In physiological studies, the cystic fibrosis transmembrane regulator (CFTR) plays a role in fluid absorption in the distal air spaces of adult lung, and alveolar type II cells cultured for 5 days have the capacity to transport Cl (cid:1) . Although both alveolar type I and type II cells express CFTR, it has previously not been known whether type I cells transport Cl (cid:1) . We studied Cl (cid:1) uptake in isolated type I cells directly, using either radioisotopic tracers or halide-sensitive fluorescent indicators. By both methods, type I cells take up Cl (cid:1) . In the presence of (cid:2) -adrenergic agonist stimulation, Cl (cid:1) uptake can be inhibited by CFTR antagonists. Type I cells express both the Cl (cid:1) /HCO 3 (cid:1) anion exchanger AE2 and the voltage-gated Cl (cid:1) channels CLC5 and CLC2. Inhibitors of AE2 also block Cl (cid:1) uptake in type I cells. Together, these results demonstrate that type I cells are capable of Cl (cid:1) uptake and suggest that the effects seen in whole lung studies establishing the importance of Cl (cid:1) movement in alveolar fluid clearance may be, in part, the result of Cl (cid:1) transport across type I cells. with inhibitor) demonstrated Cl uptake (decrease in fluorescence) ( n (cid:7) cell isolations). addition of CFTR inh172 to unstimulated cells ( n (cid:7) 5) minimal increase in the relative fluorescence, suggesting Cl (cid:1) efflux from the cells.


Starting from the von Neumann equation for the spin density matrix of a Heisenberg system, we analyze the perturbation expansion of the spin autocorrelation function by the diagrammatic technique previously applied to quantum gases. We demonstrate a number of theorems which allow us to express this perturbation series in terms of renormalized graphs only; we then derive a kinetic equation for the autocorrelation function. The main feature of this equation is that the kernel, which is highly nonlinear in the autocorrelation function itself, tends to zero in the limit of long times. The results, which are exact in the high-temperature region and in the Weiss limit (number of neighbors Z→), allow us to consider the behavior of the autocorrelation function for times both short and long. This model is a typical example of a system with a discrete unperturbed spectrum showing an irreversible behavior. © 1966 The American Physical Society.


The present invention relates to a battery unit (1) essentially comprising a plurality of cells, a housing (3) housing and surrounding said cells and means (5) for regulating the temperature of said cells by circulating heat transfer fluid. Battery unit (1) characterized in that the housing (3) comprises, at least at a bottom region on which the cells rest, at least one, preferably several, zones (s) of heat exchange between said cells and heat transfer fluid, said zone (s) being integrated (s) in the structure of said housing (3), preferably in the wall of the latter.


We present results from two Herschel observing programs using the Photodetector Array Camera and Spectrometer. During three separate campaigns, we obtained Herschel data for 24 stars at 70, 100, and 160 μm. We chose stars that were already known or suspected to have circumstellar dust based on excess infrared (IR) emission previously measured with the InfraRed Astronomical Satellite (IRAS) or Spitzer and used Herschel to examine long-wavelength properties of the dust. Fifteen stars were found to be uncontaminated by background sources and possess IR emission most likely due to a circumstellar debris disk. We analyzed the properties of these debris disks to better understand the physical mechanisms responsible for dust production and removal. Seven targets were spatially resolved in the Herschel images. Based on fits to their spectral energy distributions, nine disks appear to have two temperature components. Of these nine, in three cases, the warmer dust component is likely the result of a transient process rather than a steady-state collisional cascade. The dust belts at four stars are likely stirred by an unseen planet and merit further investigation.


This study proposes two modifications to the classical simplified real frequency technique (SRFT). A hybrid algorithm called invasive weed optimisation Levenberg-Marquardt (IWO-LM) algorithm, which combines the IWO and the LM algorithm, is used to optimise the transducer power gain. So the stochasticity of the IWO is introduced to the classical SRFT, the matching result will not be limited by the initial values. Moreover, an additional programme is added to the classical SRFT, which can transform the lumped matching network to the corresponding microstrip circuit. This improved SRFT is used to design a broadband matching network for a printed dipole base station antenna and compared with the classical SRFT, and the corresponding results show that the improved SRFT is less affected by initial values under the similar matching effect. The microstrip matching network and the antenna are integrated together, and then they are fabricated depending on the simulation. The test result of a vector network analyser shows that the bandwidth after matching is 0.728-1.01 GHz and the relative bandwidth is 32.45%, which is improved by 69.98% compared with the unmatched one.


In reexamining an earlier model by Fiorella Padoa Schippa, it is found that under a flexible price level and with wealth effects, (1) bond financing of public expenditure leads to instability, whereas money finance is always stable; (2) crowding-out of private by public expenditure is logically compatible with stability under bond but not under money finance; (3) if the system is stable, bond financing may create a larger or smaller real income compared with money finance, however, the wealth effects stemming from price level changes play an important role in the determination of these effects.


This Casenote/Comment is brought to you for free and open access by TU Law Digital Commons. It has been accepted for inclusion in Tulsa Law Review by an authorized administrator of TU Law Digital Commons. For more information, please contact firstname.lastname@example.com. Recommended Citation Charles L. Neff, Interstate Transfers of Water: South Dakota's Decision to Market Water for Coal Slurry Operations, 18 Tulsa L. J. 515 (1982).


English word stress is analysed in terms of rhythm-of alternating strong (S) and weak (W) syllables. A set of S-placement rules assigns S's to words. A set of rhythmic constraints defines well-formed configurations of S's and W's. The interaction of rules and constraints determines the accentual patterns of most words, whether simple or morphologically complex. The analysis accounts for all 'stress shifts' in morphologically related forms (e.g. solid, solidity), as well as certain phrasal stress shifts (e.g. thirteen students). The relation between S/W and degrees of stress is explored. Similarities are noted between the rhythms of discourse and those of verse. The analysis is compared to that of Liberman & Prince 1977, who also make use of alternating strong and weak syllables.*


The real-time testing system of resistivity variation regularities of loading coal was established where resistivity variation characteristics of different kinds of coal in different orientations under different loading methods were tested.Besides,resistivity variation mechanism was expounded.The research results indicate that there lies difference in resistivity changing tendency of different coal samples along with pressure's change in the initial stage of loading.Yet,resistivity shows rising trend without exception after coal fracturing occurs.In view of the same coal sample,the changing tendency of resistivity is in consistent with that of pressure.Under different loading methods,resistivity is in fine parallelism with stress.Furthermore,coal resistivity presents apparent anisotropic characteristics.In the loading process,resistivity in different orientations shows different variation regularities.Meanwhile,the conduction characteristics of coal and evolution of pore structure codetermine the variation characteristics of resistivity.


Abstract The effect of varying amounts of graphite and TiB 2 on the electrical conductivity of composite bipolarplates was systematically studied. In this study, Titanium diboride (TiB 2 ) which has a high electrical conductivity,was selected as a filler and a additive material instead of conventional graphite. For proper distribution of the fillerand matrix materials, ball milling using alumina balls was conducted for 1h, and then the hot press method wasapplied for the preparation of composite samples. The results showed a rapid increase in the electrical conduc-tivity of composite bipolar plates at the critical filler content. However, TiB 2 and graphite composite bipolar platesshowed similar increases in the electrical conductivity even though TiB 2 has a higher electrical conductivity thangraphite. In addition, it was also found that a small addition of TiB 2 to graphite filler could be very effective forincreasing the electrical conductivity and flexural strength of the composite bipolar plate.(Received March 14, 2014; Revised March 25, 2014; Accepted April 3, 2014)Key words : Titanium diboride (TiB


Titanium dioxide (TiO 2 ) surface was modi fi ed with MnO x , SnO x or (Mn 0.8 , Sn 0.2 )O x by chemisorption calcination cycle (CCC) processing. Samples modi fi ed with SnO x or (Mn 0.8 , Sn 0.2 )O x were also modi fi ed with MnO x by subsequent CCC processing. Then the decomposition activity on 2-naphthol in water was evaluated at 50°C in the dark or under visible light illumination. The modi fi cation with MnO x engendered a decrease in the sample bandgap. Although the samples modi fi ed with SnO x or (Mn 0.8 , Sn 0.2 )O x only did not show decomposition activity in the dark, they decomposed 2-naphthol in water by subsequent modi fi cation with MnO x on their surface. The results suggest that the interaction between the base material and modi fi ed MnO x plays an important role on the activity order. Samples modi fi ed with SnO x or (Mn 0.8 , Sn 0.2 )O x and MnO x exhibited decomposition activity both in the dark and under visible light. Although the activity in the dark decreased gradually through repeated use, it recovered by ultraviolet light illumination at room temperature or heating at 300°C in ambient air.


Big data is a big business, and effective modeling of this data is key. This paper provides a comprehensive multidimensional analysis of various open source tools for machine learning with big data. An evaluation standard is proposed along with detailed comparisons of the frameworks discussed, with regard to algorithm availability, scalability, speed, and more. The major tools profiled are Mahout, MLlib, H2O, and SAMOA, along with the big data processing engines they utilize, including Hadoop MapReduce, Apache Spark, and Apache Storm. There is not yet one framework that "does it all", but this paper provides insight into each tool's strengths and weaknesses along with guidance on tool choice for specific needs.


In a companion paper (see ibid., p.747-54, Jun 1993) spectral options for the synthesis of the electromagnetic fields radiated into the exterior by a pulsed electric current element inside a grounded dielectric layer are presented. The exact spectral integrals, which implement these spectral alternatives, are reduced here by asymptotic methods that extract explicit approximate forms for wavefront contributions, time-domain (TD) leaky mode contributions with space-time dependent wavenumbers and frequencies, and self-consistent hybrid combinations of both. The resulting hybrid wavefront-TD-leaky-mode algorithm is explained in physical terms and tested numerically. For both TE and TM contributions, it is found that in their domain of validity, the TD leaky modes excited within the frequency spectrum of the source pulse synthesize with remarkable accuracy the highly resolved pulse train obtained by direct tracking of multiple reflected wavefronts. Of special interest is the anomalous behavior of the TM-TD leaky modes when their angular spectra are near the Brewster angle for the air-dielectric interface. The correspondingly anomalous asymptotics is explained in detail. >


This study employed interpretative phenomenological analysis as an approach in investigating related aspects that constitutes sexual identity satisfaction among selected Filipino LGB adults. The research were participated by 13 self-identified Filipino LGB adults composed of 5 lesbians, 2 gay men, 4 bisexual males and 2 bisexual females through semi-structured interview. Findings revealed three major themes namely: self-affirmation and acceptance, positive support from family and peers and personal values and beliefs that constitutes to the sexual identity of the Filipino LGB adults.

 Key words: LGB, adults, sexual identity, satisfaction.


The threshold collision-induced dissociation method is applied to study the fragmentation patterns and to measure the dissociation energies of small anionic copper clusters (Cun−, n=2–8) and their monocarbonyls (CunCO−, n=3–7). For the bare clusters, the main reaction channels are loss of an atom and loss of a dimer. For the copper cluster monocarbonyls, the main channel is loss of CO. Dissociation energies for the loss of an atom from bare copper cluster anions, D0(Cun−1−–Cu), show even–odd alternation. The species with the highest dissociation energy, Cu7−, and the highest carbonyl desorption energy, Cu5CO−, have eight valence electrons, consistent with closed shells in the jellium model. Bond energies are compared with theoretical models.


Image captioning is a subject that has steadily gained the interest of many scholars working in the field of Artificial Intelligence (AI). Picture captioning, which combines the abilities of Computer Vision (CV) and Natural Language Processing (NLP), generates natural language descriptions based on the content of a picture or image. It is an essential part of scene interpretation. While a computer can't tell what an image is about, the human brain can. This is resolved by developing a model using Deep Learning (DL) techniques, vast datasets, and computer power. In this paper, Convolutional Neural Network (CNN) and Long Short Term Memory (LSTM) techniques are combined to implement the proposed project. Since the proposed model is data-dependent, the generated captions for photographs will only contain words from the proposed model's vocabulary.


• High-Luminosity LHC will produce ≥ 3000 fb-1 of 14 TeV pp data by ~2035. • Will improve precision of Higgs/SM measurements and searches for BSM physics. • Upgraded Inner Tracker (ITk) will replace current ATLAS tracker: • All-silicon, hermetic tracking in |η|<4.0, increased from |η|<2.5 for Run 2. • Designed to cope with high radiation doses, bandwidth, and <μ> = 200 pileup. • Strip and Inclined Pixel detectors modeled with GEANT4 simulation. • Preliminary optimization of tracker layout performed. • Track reconstruction: Silicon hits → clusters → tracks. • Simulation and tracking documented in recent ITk Strip TDR [1]. • Order of magnitude Improvement in track resolution. Vertex Fitting Event display image of h → μ μ e e event showing


The increase of data traffic in wireless networks is requiring the bandwidth of photonics for the antenna data relay. While the distribution of RF signals through Radio-over-Fiber has become a well-accepted and established technology thanks to the low loss of fibers in signal transportation, photonics still has lot to offer to the radio world. RF signal generation, detection, and conditioning (e.g., filtering, delaying, phase shifting) can be realized through photonic techniques, taking advantage of the broad bandwidth and flexibility of photonic devices, and allowing the realization of entire photonics-based radio transceivers, also including beamforming capabilities. This paper overviews the main functionalities offered by photonics in the radio scenario, highlighting their advantages and the related techniques. Then, it focuses on some examples of photonics-based radio transceiver demonstrators, reporting on their performance and discussing on their possible on-field implementation.


How to perform human mobility simulation and generate massive and high-quality individual mobility trajectories is an important and challenging research problem. Existing works generate mobility trajectories, suffering from the issues of missing either macro- or micro-scopic mobility. In this paper, we develop a mobile trajectory generation framework to simulate human mobility. This framework attempts to simulate both macro-and micro-scopic human mobility by incorporating both macro-and micro-scopic models. Our very initial results demonstrate the possibility to generate dense mobile trajectory exhibiting reasonable macro- and micro-scopic human mobility.


We consider the discretization of parabolic initial boundary value problems by finite element methods in space and a Runge-Kutta time stepping scheme. Order optimal a-priori error estimates are derived in an energy-norm under natural smoothness assumptions on the solution and without artificial regularity conditions on the parameters and the domain. The key steps in our analysis are the careful treatment of time derivatives in the H(-1)-norm and the the use of an L2-projection in the error splitting instead of the Ritz projector. This allows us to restore the optimality of the estimates with respect to smoothness assumptions on the solution and to avoid artificial regularity requirements for the problem, usually needed for the analysis of the Ritz projector, which limit the applicability of previous work. The wider applicability of our results is illustrated for two irregular problems, for which previous results can either not by applied or yield highly sub-optimal estimates.


The orthopedic fixation clamp for gripping a first elongate member and a second elongated member, between the the first and second ends and their first end and the second end the longitudinal direction of the elongated clamp shaft having a shaft axis extending, attached to the clamp shaft for rotation about the shaft axis, the first having a first clamp opening capable of receiving the first elongate member a clamp body, attached to the clamp shaft for rotation about the shaft axis, a second clamp body having a second clamping aperture capable of receiving a second elongate member, the first elongate member and means for reducing the first clamp opening regardless of the second clamping opening for securely gripping the, first for the second shaft axis independently of the clamp body And means for locking the rotational position of the clamp body, and means for reducing the second clamp opening regardless of the first clamping opening for securely gripping the second elongate member, clamp, characterized in that it comprises a means for locking the rotational position of the second clamp body relative to the shaft axis regardless of the first clamp body.


In toxic epidermal necrolysis (TEN), a wide layer of skin is peeled and an immature skin layer appears. In a short period, an epidermal necrolysis characterized by scalded appearance of skin due to febrile toxic reaction develops. The mortality rate of this disease is high (20-70%), due to dramatic drug reactions of the skin. The disease resembles mostly to erythema multiforme (EM), Steven Johnson syndrome (SJS), and staphylococcal scalded skin syndrome (SSSS). Toxic epidermal necrolysis is more prevalent in adults, though it can be encountered in all ages. It can be evaluated as an upper respiratory tract infection at first sight, since its initial symptoms are fever, conjunctivitis, or pharyngitis. 5 The main cause of mortality in this disease is systemic infections, such as Staphylococcus aureus and Pseudomonas aeruginosa. Adverse effects of drugs (especially sulfonamides), infections, malign diseases, and graft versus host disease are mainly blamed as causes of TEN. The early histopathological finding of TEN is the presence of necrotic keratinocytes in the dermalepidermal junction. Inflammatory cells can be seen in skin biopsies. Furthermore, Nikolsky phenomenon can also be used for diagnosis. The disease is evaluated as a burn case in many centers. Early diagnosis, timely interventions, and sufficient supportive therapy may save the life of these patients. 1,2


Internal corrosion control technology in pipeline includes gravity drop method to measure corrosion speed and pour into anti-corrosion doze.Since"Ninth Five Year Plan",west south oil field company has developed new type anti-corrosion doze for pipeline,and pour methods,effectiveness evaluation of anti-corrosion,and also established pipeline internal corrosion in line monitor system and gotten better way to restrain pipeline internal corrosion.


Based on literature analysis and market investigation,this paper analyzes the current conditions and existing problems of the sports facilities in Shanghai.It points out some main factors affecting the development of the facilities and makes some suggestions on strengthening macro- guidance and control,encouraging private investment in the market of physical exercises,establishing an association for the privately-run sports facilities,etc.


SHI Tuo was a famous writer in Chinese modern literary history.Comparing with writers of the Beijing School and the Left-wing,SHI Tuo's novels embodied distinctive characteristics and connotation.However,in contrast with works of other writers of the same era,differences and uniqueness displayed obviously in SHI Tuo's novels,but a considerable number of scholars ignored it usually.SHI Tuo's novels formed unique style and obvious characteristics,and acquired the prominent artistic value in Chinese modern literary history.To fully understand the important significance of SHI Tuo's novels in Chinese literary history will be very helpful for us to further deepen and expand the research on his works.


One of the most pressing global concerns is ensuring high levels of human well-being without overburdening natural resources. The impact of natural resource abundance on the economy's monetary dimensions has long been controversial, with researchers debating whether it is a blessing or a curse. Recently, focus has shifted to its impact on non-monetary attributes (i.e., human well-being), with conflicting empirical evidence with respect to existence of the resource curse. However, studies on the indirect impact of natural resources on well-being are rare. This inquiry extends previous research by investigating the effect of natural resource abundance on human well-being and the underlying mechanisms that may clarify the convoluted link between the two variables in the UAE from 1990 to 2019. The novel contribution of this research is the evaluation of the resource curse concept from a broader perspective by considering how resource endowments indirectly affect human well-being via environmental quality, human capital, and governance channels. To this end, in the present study, we utilized the autoregressive distributed lag (ARDL) technique for cointegration and deployed the vector error correction model (VECM) for causality investigation. The ARDL results indicate cointegrated variables with diverse integration orders, signifying a long-term bond. Furthermore, the outcomes endorse the notion that resource endowment is inversely related to well-being as calibrated by the Human Development Index (HDI), corroborating the "Resource Curse Concept", whereby large resource endowments impede human well-being. In terms of transmission channels, natural resources improve human well-being through environmental quality. In contrast, both human capital and governance have insignificant impacts on the influence of natural resources on well-being. Therefore, resource endowments improve human well-being as long as they do not harm the environment. The present analysis also resulted in the development of a feedback hypothesis between natural resource endowments and human well-being. The findings of this study provide several insights into the control of the direct and indirect adverse effects of natural resources on human well-being, the foremost being the provision of incentives for low-carbon energy use, reducing energy intensity, and assisting businesses engaged in R&D to minimize the cost of employing renewables, as well as investments in low-carbon technologies/cleantech and environmental technologies.


Disorientation is a common feeling for all users of zoomable multi-scale maps, even for those with good orientation and spatial skills. We make the assumption that this problem is mainly due to the desert fog effect, documented in human–computer interaction within multi-scale zoomable environments. Starting with a collection of reported experiences of disorientation, this paper explores this notion from the spatial cognition, philosophical and human–computer interaction perspectives and proposes a model of disorientation in the exploration of multi-scale maps. We argue that disorientation is a problem of reconciliation between the current map view and the mental map of the user, where landmarks visible on the map or memorised in the mental map play a key role. The causes for failed reconciliation are discussed and illustrated by our collected experiences of disorientation.


The quest for quality in education has necessitated the need for innovative leadership in Ghanaian schools. In pursuit of this, teacher educational institutions have through the traditional and distance education systems revised their programmes to ensure that appropriate leadership qualities are developed in teachers to enable them provide the needed classroom and school level leadership for facilitating teaching and leaming in schools. Achieving this feat requires relevantleadership competences. in this paper; we explore some indicators of leadership competences within the Ghanaian cultural context. Drawing on literature from Western authors, and an intetpretive study involving thirty Ghanaian primary headteachers, we contrast competences from competencies and conclude with a discussion on the interplay of the two notions in shaping the professional performance of primary school headteachers in the country.


Abstract : In recent years considerable effort has been directed towards improving the treatment of durational structure in hidden Markov model (HMM) based approaches to speech pattern modelling. In general these studies have been concerned with more accurate modelling of the variations in segment duration which occur when words are spoken at a nominally constant speaking rate. However, recent work has shown that some of the performance gains which can be achieved by improved duration modelling are lost when the words in the test set are spoken at a different rate from those in the training set. This memorandum presents an approach to solving this problem based on the capture and use of information about state duration correlations. A method for measuring correlations between the durations of adjacent states in a HMM is described. The method involves expanding a standard HMM into a special type of hidden semi-Markov model (HSMM), called a Correlated Duration HMM (CDHMM), in which each state of the original HMM is expanded into a set of fixed-duration HSMM states. The probabilities associated with transitions between these states are measures of state duration correlation. Experiments are described in which the CDHMM method is applied to a set of sentences spoken at four different speaking rates. Great Britain.


With the Belt and Road as the development background of the times, the cross-border e-commerce business has also developed. In general, cross-border e-commerce fundamentally breaks the boundaries between time and space, and can further realize the close transactions between consumers and operators. This kind of transaction is completely free in theory. As a big country in cross-border trade, China has become a core force in the process of bilateral trade between many countries and plays a vital role. In this paper, the author takes the Belt and Road and cross-border e-commerce as the entry point, and actively explores the cross-border e-commerce development model of the Belt and Road Economic Zone.


Objective: To control a second-wave COVID-19 outbreak, the state of Victoria in Australia experienced one of the world's first long and strict lockdowns over July-October 2020, while the rest of Australia experienced 'COVID-normal' with minimal restrictions. We (1) investigate trajectories of parent/child mental health outcomes; and (2) identify baseline demographic, individual, and COVID-19-related factors associated with mental health trajectories. Method: Online community sample of 1,877 Australian parents with rapid repeated assessment over 10 time-points over April-October, 2020. Measures assessed parent mental health (Depression, Anxiety and Stress Scales-21); child depression symptoms (13-item Short Mood and Feelings Questionnaire); and child anxiety symptoms (four-items from Brief Spence Children's Anxiety Scale).Results: Mental health trajectories shadowed COVID-19 infection rates. Victorians reported a large peak in mental health symptoms at the time of the second-wave lockdown compared to other states. Key baseline predictors, including parent and child loneliness (standardized regression coefficient [β]=·09-·39), parent/child diagnoses (β=·11-·22), couple conflict (β=·09-·19), and COVID-19 stressors, such as worry/concern about COVID-19, illness, and loss of job (β=·07-·22), predicted elevated trajectories. Effects of predictors on parent and child mental health trajectories are illustrated in an online interactive app for readers (https://lingtax.shinyapps.io/CPAS_trend/).Conclusion: Our findings provide evidence of worse trajectories of parent and child mental health symptoms associated with strict, sustained, COVID-19 lockdown in Victoria, compared to non-locked states in the rest of Australia. We identified several baseline factors that may be useful in detecting high risk families who are likely to require additional support early on in future lockdowns.


Objective To assess the technical feasibility, anatomical and functional outcome of laparoscopically assisted sigmoid colon vagino-plasty (LASV) in patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.Methods From April 2002 to June 2003, sixteen patients with MRHK syndrome underwent LASV. The operative technique and the complications were delineated, and the anatomical and functional results were reviewed.Results The mean follow-up period was 9 months(range 5-13 months) with the mean operation duration 256min (range 215-380 min), and the mean fall in haemoglobin 25 g/L (range 13-45 g/L). One case needed blood transfusion. The perioperative complications were urinary tract infection(n=1), infection in assisted incision wound (n=2) with one required reopening and drainage. The mean hospital stay was 10.3 days (range 8-18 days). The mean length of the newvagina was 11.8cm (range 10-14 cm). The newvaginal introitus could not admit two fingers in breadth in three cases with one demanded dilation and one required surgical plasty 6 months after the operation. Of the twelve patients who were sexually active, started intercourse at the mean duration of 4.2 months after operation.Conclusion Although the outcome is not perfect, LASV is an effective approach for patients with MRKH syndrome.


The radial increment of spruce annual rings is analyzed; the influence of age on the increment dynamics is determined. The increment indices are calculated; the tree groups are selected having similar response to climatic effect complex; the assessment of wood plants sensibility to affecting factors is given.


Traditional online shopping just a simple commodities classification and display, for e-commerce businesses and consumers shopping without depth study.. Online shopping process for consumers to choose different tropism of goods, the introduction of decision tree classification method based on customers to buy goods on the network to analyze the behavior and dig out from the tree of the main factors affecting online shopping as well as various factors on the network impact strength of buying behavior. The experimental results show that this method can effectively classify clients on the network and favor decision analysis.


The utility model discloses a detection device used for prediction of soldier mission-performing capability. The device comprises a step calculation module which is used for statistics of walking steps of soldiers and transmitting the walking steps after statistics to a control module; an acceleration sensing module which is used for detecting walking acceleration of the soldiers and transmitting walking acceleration of the soldiers to the control module; an altitude height sensing module which is used for detecting altitude height information of the soldiers and transmitting the altitude height information to the control module; the control module which is used for controlling detection modes of the detection device and is also used for transmitting the received walking steps, walking acceleration of the soldiers and the altitude height information to a data communication module; and the data communication module which is used for interaction with a detection platform and transmitting the walking steps, walking acceleration of the soldiers and the altitude height information to the detection platform. The physical condition of the soldiers in battles can be accurately mastered via detection of remaining physical efficiency so that accurate prediction of fighting ability of the soldiers is guaranteed.


through the communication interfaces. The monitoring system, operating on a computer or a handheld device, can confirm that an incident occurred using fuzzy analytic hierarchy process (fuzzy-AHP) by these data and establish accident models for earlier warning. These models can be transmitted to the modules making them more intelligent. Since each module developed in this paper has the function of network communication, it can be an Internet of Things (IoT) node, and the monitoring system can form a regional disaster prevention system


This report addresses the California Community Colleges Board of Governors' Initiative for Developing California's New Workforce. The report argues that many workforce training programs are still based on obsolete paradigms. Rather than offering the long-term skills and career development necessary to succeed in a high-performance workplace, these programs provide only limited preparation designed to help individuals into entry-level jobs. The result of this "work first" policy is the rapid growth of a new class of low-income wage earners whose skills are largely irrelevant to many of the new economy's employers. Many of this new class are former recipients of welfare. These are often the people most in need of the quality education and training community colleges can provide. The report suggests that workers need to be trained for more than a job--they must gain the skills that enable them to build a career. Career ladders are long-term career progression pathways that help people advance, particularly in high-wage, high-growth careers. Creating a career-ladder system will require new kinds of partnerships among employers, workforce development agencies, community colleges, and community organizations. The report argues for creating a single, unified system that reflects California's new economy.


The experiments reported in this paper demonstrate that ependymal cells can stimulate a regenerative outgrowth when implanted into the limb of a lizard. Simple limb amputation, amputation followed by a sham operation, and amputation followed by the implantation of a cartilage tube from a tail regenerate were ineffective in causing the hind limbs of Xantusia vigilis to regenerate. However, amputation followed by the implantation of a cartilage tube containing ependyma caused regenerative outgrowths in 82% of the treated limbs. These results show that ependymal cells, in addition to initiating tail regeneration in their normal location, can when transplanted to the limb, initiate limb regeneration.


Introduction The Hippo pathway regulates tissue growth and organ size and its dysregulation/inactivation leads to a host of cancers such as breast, colon and bladder cancer. YAP/TAZ are transcriptional regulators which among other functions enhance cell growth. The core kinase cassette consisting of LATS1/2, MST1/2, SAV and Mob phosphorylate YAP and TAZ promoting their cytoplasmic localization and degradation. Currently much remains to be learned about the upstream regulators that modulate the pathway. The purpose of this study was to carry out a genome wide positive selection CRISPR screen to uncover novel upstream regulators of the Hippo pathway. For the screen it is necessary to generate stable cell lines with a reporter responsive to YAP/TAZ. This was carried out by expressing a fusion protein where the catalytic domain of Caspase-9 is fused to a modified FKBP (FK506 binding domain) under the transcriptional control of YAP/TAZ. This protein is homodimerized by the addition of a drug AP20187 which triggers an apoptotic pathway leading to cell death. When YAP/TAZ activity is disrupted, cells are expected to survive, despite addition of AP20187. The cell lines are also designed to express Cas9 which will be used to knockout the genes in the human genome using a 90K guide RNA library targeting over 17 500 human genes. Material and methods T24 bladder cancer cells were maintained in McCoy's 5A medium with 10% FBS. Lentiviral constructs of Cas9 and FKBP-Caspase9 were obtained (courtesy Dr. Angers) and the YAP/TAZ responsive FKBP-Caspase9 was constructed by restriction digestion and ligation. Using lentivirus T24 cells were transduced with both constructs and single clones were isolated expressing both FKBP-Caspase9 and Cas9 to obtain the screen cell line. The dimerizer AP20187 was obtained from Clontech. The lentiviral library TKO-v1 (gift from Dr. Jason Moffat) was applied to the T24 screen cell line using lentiviral transduction. After 3 days of puromycin selection, the pool of surviving cells were split into replicates and AP20187 was added to one set of replicates while the other set was treated with ethanol as control. Once the AP20187 treated plates were confluent, the cells were collected, genomic DNA was extracted and sequenced by next generation sequencing. Results and discussions The top genes enriched in the surviving cells included well known members of the Hippo pathway including YAP and TAZ along with new proteins. Conclusion These new proteins are currently being investigated for their role in the Hippo pathway.


The present work is based on using the reinforced learning technique on evolutionary computation for compressing an image. We have reinforced the best code vectors for a codebook in vector quantization, and kept them alive for the next generation until we got the best image. A genetic algorithm model was designed using reinforced learning with the pairwise nearest neighbor approach (PNN). The proposed method was evaluated with respect to quality of compressed image by calculating Peak Signal to Noise Ratio (PSNR). We used Lena image for our experiments and the PSNR value for proposed method is 34.6.


A biogenic silica analysis was performed on 857 samples at ODP Site 1144 in the northern South China Sea. The correlation of opal content and MAR with oxygen isotopic records of plankton foraminifera shows that they increased during glacial periods and decreased during interglacial. The increases of opal content and MAR after the middle Pleistocene (about 0. 9 Ma) result from the higher surface productivity, which was induced by the intensified monsoon circulation after the " Mid ?Pleistocene Revolution" and the special situation of Site 1144. The time ?sequence spectral analyses of oxygen isotopic record, opal content and MAR reveal that the variability of the surface productivity were dominantly forced by the earth orbital cycles.


The paper argues that multiple equilibria-whether non-stationary or stationary- are a generic property of dynamic rational expectations models. In light of this, this paper proposes a selection criterion for choosing between these multiple equilibria in an important class of dynamic rational expectations models. The criterion is based on the idea that agents can be assumed to coordinate their beliefs around the limit of a finite-horizon equilibrium. For three examples examined, all of which can have multiple stationary, i.e., non-explosive, rational expectations equilibria, there is, among the multiple equilibria of an infinite-horizon model, only one that is the limit of a finite-horizon model.