The purpose of this study was (1) To analyze the level of comparative and competitive advantage of sago processing enterprises in East Kolaka Regency? (2) Examine the impact of government policy on the comparative and competitive advantage of sago processing enterprises in East Kolaka Regency. The study employed the Policy Analysis Matrix (PAM) analysis. The population of the study was sago-processing farmers in the sub-regency of Tirawuta of East Kolaka regency. The samples were 15 respondents. The variables of the study were output price, foreign costs, domestic costs, private price, and shadow prices. The results showed that the sago processing business in East Kolaka Generally sago processing business in East Kolaka have a positive level of comparative advantage with the value of Domestic Resource Cost Ratio (DRCR) of 0.27 and has a positive level of competitive advantage with value Private Cast ratio (PCR) 0.31. This suggests that the sago processing business in East Kolaka feasible to develop even enhanced in the future. Government policies that have not been in favor of sago processing business in East Kolaka lead this comparative effort advantage tend to decrease with Effective indicator Protection Coefficient (EPC) of 0.76, while the output policy causes Transfer Input value of IT value of Rp. (134.900). This indicates the absence of a purchase price policy on output area (Aci sago).


ABSTRACT Germline mutations in RECQL4 helicase are associated with Rothmund-Thomson syndrome, which is characterized by a predisposition to cancer. RECQL4 localizes to the mitochondria, where it acts as an accessory factor during mitochondrial DNA replication. To understand the specific mitochondrial functions of RECQL4, we created isogenic cell lines, in which the mitochondrial localization of the helicase was either retained or abolished. The mitochondrial integrity was affected due to the absence of RECQL4 in mitochondria, leading to a decrease in F1F0-ATP synthase activity. In cells where RECQL4 does not localize to mitochondria, the membrane potential was decreased, whereas ROS levels increased due to the presence of high levels of catalytically inactive SOD2. Inactive SOD2 accumulated owing to diminished SIRT3 activity. Lack of the mitochondrial functions of RECQL4 led to aerobic glycolysis that, in turn, led to an increased invasive capability within these cells. Together, this study demonstrates for the first time that, owing to its mitochondrial functions, the accessory mitochondrial replication helicase RECQL4 prevents the invasive step in the neoplastic transformation process. Highlighted Article: Localization of RECQL4 to the mitochondria is required to maintain mitochondrial functions, prevent aerobic glycolysis and cellular invasion.


Magnetic and crystal structures of superconducting XyFe2 − xSe2 (X = Rb and K with Tc = 31.5 and 29.5 K) have been studied by neutron powder diffraction at room temperature. Both crystals show an ordered iron vacancy pattern and the crystal structure is well described by the I4/m space group with the lattice constants a = 8.799, c = 14.576 and a = 8.730, c = 14.115 Å and the refined stoichiometry x = 0.30(1), y = 0.83(2) and x = 0.34(1), y = 0.83(1) for Rb and K crystals, respectively. The structure contains one fully occupied iron position and one almost empty vacancy position. Assuming that the iron moment is ordered only on the fully occupied site we have sorted out all eight irreducible representations (irreps) for the propagation vector k = 0 and have found that irreps τ2 and τ7 fit the experimental data well with the moments along the c axis. The moment amplitudes amounted to 2.15(3) µB, 2.55(3) μB for τ2 and 2.08(6) μB, 2.57(3) μB for τ7 for Rb and K crystals, respectively. Irrep τ2 corresponds to the Shubnikov group I4/m′ and gives a constant moment antiferromagnetic configuration, whereas τ7 does not have a Shubnikov counterpart and allows two different magnetic moments in the structure.


The 20C embraced Restoration comedy as the quintessence of comedy of manners and adored The Country Wife as one of the most brilliantly glittering example of the genre. The definition of that genre, however, arose in the current era, and it has distorted our perspective on this comedy. We must consider the 17C dramatic meaning of manners in order to understand the characters' back stories, motivations, and social milieu. Such an analysis can guide us in making distinctive, precise interpretive decisions about the characters in this comedy—decisions that are based in the text and in the historical context. These character interpretations can accentuate for a 21C audience the 17C satiric and comedic elements enmeshed within the text of The Country Wife.


We present a thorough analysis of U(1) generators in all of the nine possible symmetry-breaking patterns that reduce SU(7) down to SU/sub c/(3) x SU(2) x U(1). There is one allowed representation that contains three generations of leptons and at least two generations of quarks, and satisfies anomaly freedom, reality under SU/sub c/(3) and U/sub e/m(1), and complexity under SU/sub c/(3) x SU(2) x U(1). In addition, three other representations, two having only one and two of the three lepton-quark generations complex with respect to SU/sub c/(3) x SU(2) x U(1), and the other having fractionally charged color singlets in pairs embedded in the fundamental representation (7), are also analyzed for completeness.


Unsaturated β-dicarbonyl compounds, e.g. (I), (III)/(VI), (VIII), and (X) undergo intramolecular cyclization by reaction with a catalytic amount of I2—PPh3 affording spiro enol ether derivatives with complete regio- and stereoselectivity.


Based on experience and scientific advancements over the past two decades, a revised approach for the assessment of the allergenic potential of newly expressed proteins (NEPs) in genetically modified (GM) plants is warranted. NEPs are most often not native to the crop genome, and thus regulatory reviews of the safety of GM plants include an assessment of the allergenic potential of NEPs. International standards for the assessment of allergenicity first developed in the mid-1990s required a series of characterization studies to be conducted that are, to some extent, still applicable today to the risk assessment of GM plants, with most modern versions represented in the Codex Alimentarius. This standardized guidance on allergenicity assessments, including the required characterization studies, presented two primary challenges. First, there was (and still is) no defined and accepted model (animal or in vitro) for directly testing allergy potential. Second, bioinformatic analyses were prescribed using thresholds for hazard identification that were neither universal for all allergens nor tested prior to the implementation of requirements into guidance documents. Herein, risk assessment principles are applied to structure the assessment of the allergenic potential of NEPs. This allergy risk assessment is built on a foundation of: 1) identifying hazard by assessing similarity to known allergens, and 2) assessing exposure when a hazard is identified. Supplementary studies such as IgE binding may need to be performed in special cases. These recommended revisions to current approaches to the assessment of allergy potential are designed to ensure a realistic, case-by-case approach, and consider updated molecular biology, genomics, and bioinformatic techniques that were unavailable when earlier allergy risk assessment approaches were established.
doi: 10.21423/jrs-v09i1mcclain


We report the fabrication of flexible integrated circuits (ICs) for complementary metal-oxide semiconductor image sensors by using the layer transfer process of fully depleted silicon-on-insulator (FDSOI) circuits onto a plastic substrate. Our device combines the high performance of single crystalline silicon metal-oxide-semiconductor field-effect transistors (MOSFETs) and the flexibility of plastic. A 6-μm thick FDSOI device with 50-nm thick MOSFET active layers and aluminum wires is successfully transferred to a polyethylene terephthalate substrate. In addition to mechanical flexibility, operation of ICs including MOSFETs and 101-stage ring oscillators is confirmed, which demonstrates their potential in flexible highly integrated devices, such as image sensors and displays.


The solidification of synthetic white cement is monitored by nuclear magnetic resonance. Proton signals in several different environments are resolved and the time evolution of their dynamics and relative numbers is presented. The amounts of liquid water (the water which has not yet entered the solid structure to become crystalline water) and Ca(OH)2 crystallites are monitored precisely during hydration. The technique gives a quantitative insight into the hydration process as well as the growth (and decay) pattern of various cement paste components.


This paper presents a modified form of Dynamic Programming for solving Unit Commitment problem which encompass pre-dispatch and economic dispatch sub problems. The predispatch sub problem in UC is solved by unit classification based on Full Load Average production Cost. Solution for second sub problem is obtained using the modified form of DP. Modified form of dynamic programming technique suggested by this paper provides the generation schedule of individual generators in an analytical form even for a large number of variables without the traditional Lagrangian form. 10-generator system is tested using this algorithm for 24-hour scheduling horizon and the test result is compared with various other techniques. The result analysis exhibit the superiority of the proposed method.


FIREBALLS OVER THE NULLARBOR DESERT OF SOUTH WESTERN AUSTRALIA P. A. Bland, P. Spurný, L. Shrbený, J. Borovicka, A. W. R. Bevan, M. C. Towner, T. McClafferty, D. Vaughan, G. Deacon. Impacts & Astromaterials Research Centre (IARC), Dept. Earth Sci. & Eng., Imperial College London, SW7 2AZ, UK (email@example.com); Astronomical Institute of the Academy of Sciences, Fricova 298, CZ-251 65 Ondřejov Observatory, Czech Republic (email@example.com); Department of Earth and Planetary Sciences, Western Australian Museum, Francis Street, Perth, WA 6000, Australia; Planetary and Space Sciences Research Institute, The Open University, Milton Keynes MK7 6AA, UK; Western Australian Museum Kalgoorlie-Boulder, 17 Hannan St., Kalgoorlie, WA 6433, Australia; 50 Government Rd, Subiaco, Perth.


This paper discussed fashion,clothing and the relationship between them.It also introduced the theories on the dress fashion which includes the "Class Differentiation Theory" by Simmel,the "Identity Ambivalence Theory" by Davis,the "Collective Selection Theory" by Blumer,and the "Cultural Production Theory" by Baudrillard.Finally,this paper put forward some issues that should be paid attention to in the research of dress fashion in China.


A new type of global stability is introduced and its equivalent Lyapunov characterization is presented. The problem of global stability of the compact set composed by all invariant solutions of a nonlinear system (several equilibriums, for instance) is analyzed. Consideration of such set allows us to present global stability properties for multi-stable systems.


The using mouse Immunoprecipitation using irrelevant Ab) the specificity of the anti HA-antibody. Proteins were separated by SDS-PAGE, transferred to a nitrocellulose membrane and the HA-ANXA1 band was analyzed using PhosphorImager. Thereafter, the membrane was processed for immunodetection of immunoprecipitated HA-ANXA1. Total proteins were kept before IP to monitor p38AGF expression. Tubulin α is also shown as a loading control. (B) Quiescent HUVECs transiently expressing an empty vector (EV) or HA-tagged wild-type ANXA1 1B. Cells were extracted as described in Experimental Procedures. After extraction, the HA-tagged proteins were immunoprecipitated using anti-HA mouse antibody. Proteins were separated by SDS-PAGE and transferred to a nitrocellulose membrane. The membrane was then exposed for autoradiography, analyzed using PhosphorImager and processed for immunodetection of immunoprecipitated HA-ANXA1. Representative blots of at least two separate experiments are shown in A and B.


Thermal Infrared Multispectral Scanner (TIMS) imagery and Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) imagery are registered to each other for seven scenes. Cloud area, as determined by applying the 3-band ratio method to AVIRIS imagery, is used to determine the optimum temperature threshold in the TIMS imagery. For this set of scenes, a threshold of 2 degree(s) to 3 degree(s) below the background temperature provides for the most accurate cloud pixel identification. Five to 8% differences in cloud area are found when comparing cloud pixel identification between AVIRIS and TIMS. Some of the differences are due to misregistration; however, at least half are due to differences in the mensuration process. It is demonstrated that cloud edges have a distribution of temperature thresholds, indicating the difficulty of locating cloud edges with a single temperature threshold. It is found that cloud edges occupy nearly half of the entire range of scene temperatures, significantly overlapping the distribution of background temperatures.


The on-board generators of hybrid electric vehicle are overviewed. Based on the doubly salient electro-magnetic machine (DSEM), a new brushless DC (BLDC) generator system for the extended-range electric vehicle (E-REV) application is proposed. The principle of the DSEM, the configuration of the generator system, and the E-REV powertrain are introduced. The operation principle and the power matching relationship among the generator system, battery and the drive system are investigated, and the control strategy is presented as well. A 45kW doubly salient BLDC generator and the associated generator system controller for the E-REV application are designed and developed. The experimental results indicate that the doubly salient BLDC generator system exhibits simple and reliable configuration, convenient controllability and high operation performance with constant current/power output capability. The new BLDC generator system is a promising option for the increasing E-REV application.


The inclusive distributions of hadrons produced in ..nu..(anti ..nu..) Ne interactions are studied as a function of the momentum fraction z. Discrepancies between the data and existing parametrizations of the quark-parton model are found. 11 references.


It is well known that the Zn-air battery dept of discharge is mainly governed by the electrochemistry of zinc anode in concentrated alkaline solutions leading to undesired precipitation of insulating zinc oxide at the electrode surface due to progressive increase in zincate concentration. Among the different approaches adopted to overcome this problem, mechanically and electrically rechargeable as well as refuelable systems have been deeply studied for automotive and stationary applications. In a refuelable Zn-air battery, the alkaline aqueous electrolyte is pumped into the cell, either carrying Zn electroactive fuel or flowing through a packed bed of Zn particles. In a previous paper, we adopted a mechanically refuelable tapered-end flow Zn-air fuel cell with Zn micro-spheres, and we studied the effect of electrolyte aging on the behavior of the Zn anode during battery discharge. The results have shown that the cell potential decrease in the battery discharge curve is mainly due to the anodic overpotential increase, as evidenced by means of EIS (Electrochemical Impedance Spectroscopy) measurements. Given that this effect can be attributed to the physicochemical modifications induced by the Zn passivation occurring at higher zincates concentration, the performance of the battery system can be notably improved by a relevant regeneration of spent alkaline zincate bath.
Here, we propose a novel method to recover zinc from alkaline zincate baths by using aluminum electrodes. Aluminum metal and zincate ions give place to a single-displacement reaction producing a layer of zinc on the Al surface. The deposits of zinc metal on aluminum foils have been studied by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), and the electrochemical process has been followed by open circuit measurements in order to put the basis of future developments.


This study aimed to evaluate the proximate and vitamin C of Physalis. Two species of Physalis, namely, P. angulata L. and P. peruviana L., used as models for a comparative study. Proximate composition, fiber, and vitamin C of all part of Physalis, i.e., leaf, stem, bud, and fruit of Physalis were analyzed. Physalis angulata collected from Pagaden subdistrict (latitude: 6030'24" S, longitude: 107048'74"E, elevation: 55 MAMSL) Subang District, West Java Province, and Physalis peruviana collected from Pamulihan subdistrict (latitude: 6052'27.06"S, longitude: 107049'24.95"E, elevation: 947 MAMSL), Sumedang district, West Java Province. The results of the study showed that the existence of proximate composition and vitamin C in plant shoot of P. angulata and P. peruviana relatively evenly spread. The proximate composition and vitamin C of Physalis angulata had the same pattern as compared to that of Physalis peruviana. The results of paired sample test showed that there were no significant differences in proximate composition and vitamin C between Physalis angulata and Physalis peruviana.


Micro-optical-electromechanical systems for microfluidic applications include typically different constituents, as optical fibers, waveguides, wavelength selection gratings and microfluidic parts, all on a single chip. In this work high quality micrometer-period metal and submicrometer silicon diffraction gratings are fabricated by e-beam lithography and reactive ion etching. Fabricated gratings' quality and optical behaviour is investigated. Sub-micrometer period diffraction gratings can be used as high selective optical grids in the visible re- gion, as well as diffractive grids in UV and X-ray regions. Examples of obtained 2D and 3D diffraction structures are presented.


The grid-forming and grid-following controls are adopted in three-phase voltage source converters according to different grid conditions. However, the basic operation principle of the two kinds of control is different and will lead to the instability of the grid-connected system through various paths. In this article, the energy function model of the grid-forming and grid-following controlled converters are established and compared in detail. The influence of system parameters is studied, and the large-signal stability boundaries are derived through a general method. Moreover, compared to the grid-forming controlled converter, the grid-following converter will lose stability by exhibiting a varying damping coefficient transient. The equivalent damping coefficient can be used as a criterion of whether the grid-forming/following control is suitable for the weak/strong grid condition. The simulation and experiment results show the difference of the transient process and validate the control criterion for different grid strength under large-signal disturbance.


Sparse representation and dictionary learning-based image denoising algorithms approximate the clean image patch by linear combination of few dictionary atoms. Clearly, residue after completion of denoising must be similar to the contaminating noise. Ideally, clean image patch is perfectly recovered if residue is exactly contaminating noise. Hence, for better denoising, residue must be enforced to possess characteristics similar to the contaminating noise. In this paper, we model residue such that proximity between residue and contaminating noise is increased. The proposed mathematical model makes sure that the residue is as random in nature as contaminating noise. This is achieved by unique sparse coding and dictionary update stages developed based on modelling of randomness in residue. The proposed algorithm is tested on additive white Gaussian noise (AWGN), additive coloured Gaussian noise (ACGN) and Laplacian noise. Since performance of the image denoising algorithms also depend on image effective bandwidth, therefore, in this paper we have generated synthetic images with known effective image bandwidths. These images are generated using the discrete cosine transform (DCT). The proposed algorithm is also tested on these images. The proposed algorithm is compared with state-of-the-art algorithms. The comparison on the bases of peak signal-to-noise ratio (PSNR), structure similarity index measure (SSIM) and feature similarity index measure (FSIM) indicate that the proposed algorithm is able to produce often better and competitive results.


Myosins are actin-based molecular motors that are found in almost all eukaryotes. Phylogenetic analysis allows the discrimination of 37 different types of myosins, most with unknown functions. Recent work in Drosophila has revealed a crucial role for type ID unconventional myosin in left–right asymmetry. Mutations in Myosin ID completely reverse the left– right axis (situs inversus), a phenotype that is dependent on an intact actin cytoskeleton. How this myosin might orient the left– right axis has began to be elucidated by showing that it interacts directly with b-catenin, suggesting that myosin ID interacts with the adherens junction to control the direction of organ looping. This is the first demonstration of a role of a myosin in body patterning. Introduction In Bilateria, the establishment of a left–right (L/R) axis is essential for the organization and function of the brain and viscera [1,2]. In contrast to the symmetrical shape of the external body, the internal organs show complex patterns of L/R asymmetry in their morphology and position. Asymmetry arises during development following three basic morphogenetic processes: first, unilateral positioning — organs sit on one side relative to the midline, e.g. heart or spleen; second, directional looping — tubular organs (e.g. gut) coil in a stereotyped direction (dextral or sinistral); and third, handed differentiation, whereby bilateral organs, such as the brain and lungs, differentiate distinct left and right parts. Symmetry breaking is the primary and essential step during L/R development. It takes place during embry-ogenesis, after the two main axes (anterior–posterior and dorsal–ventral) have been established [3 ]. De novo asymmetry is then communicated to the whole body through identified cascades of asymmetric expression of genes, including the conserved nodal pathway [3 ,4 ,5]. How L/R asymmetry arises and how it becomes oriented relative to the two main axes are central issues. The fundamental problem of symmetry breaking was conceptualized early by Brown and Wolpert [6], who proposed that it could result from molecular chirality: they hypothesized that a handed molecule capable of self-orientation along the AP and DV axes could determine the L/R axis. This hypothetical molecule, termed the 'F-molecule' (each branch of a three-dimensional F defining one axis; see Figure 1), would be an L/R determinant, in other words a molecule that can decide what is left and what is right. Among other possibilities, it has been proposed that molecular motors capable of moving along polarized fibers could act as F-like …


The African oil palm weevil, Elaeidobius kamerunicus is an effective pollinator of oil palm. Each individual palm produces exclusively male or female inflorescence so that the success of pollination depends on the ability of the pollinator to transfer pollen from male to female flowers. The objective of this research was to study the amount of pollen carried by E. kamerunicus between male and female inflorescences (pollen load) and the amount of pollen carried on each part of the weevil's body (pollen distribution). Fifty each of male and female  E. kamerunicus individuals were collected from male and female flowers on trees in 3 locations: Siantar (North Sumatra), Dramaga (West Java), and Morowali (Central Sulawesi). Data on pollen load and pollen distribution on the weevil's body were analyzed using ImageJ software. Results show that E. kamerunicus individuals collected more pollen from male flowers than from female flowers. In addition, male insects carried more pollen on their bodies than female insects. Pollen distribution on weevil body parts was highest on the elytra, followed by the thorax, abdomen, legs, and head respectively.


The pathophysiology of the blood-brain barrier (BBB) has been described as an important factor in central nervous system disease and continues to be a topic of great interest to many researchers from a wide range of disciplines. The award of three Nobel prizes, those in medicine (MR imaging),


When I was in a preschool I found out that many children were using their dialects while speaking; therefore I decided to do a research on the Use of dialects in preschools of the Slovene Littoral. I wanted to research the speech of children in other preschools in the Littoral and determine, if the dialects were being used in other preschools as well.

In the theoretical part of the thesis I presented the speech, speech development, encouragement of speech, language, language features, roles or functions of the Slovene language (mother tongue, second language or language of the environment, foreign language, language of education, learning subject, national, official language, one of the official languages of the European Union, the Slovene language as a means of communication and the subject of discovering), social genres of the Slovene language, literary and colloquial language, dialects in Slovenia, reasons for dialects, Littoral dialect and the use of literary language and dialects in preschools.

For the empirical part of the thesis I prepared a questionnaire because I wanted to know how often and in what situations the teachers and the children use their dialects, and whether if and how the teachers encourage the use of the literary language with children.


A poll of the attitudes of Connecticut citizens toward children in the state was commissioned by Kids 2000, a project of the Connecticut Association for Human Services, and was conducted by the Institute for Social Inquiry at the University of Connecticut as a telephone interview of 500 randomly selected adult residents. Questions asked covered such topics as trends in children's quality of life, the priority placed by the state on children's programs, willingness to pay more taxes for programs earmarked for children, state provision of child care, and provision of health care for pregnant women and children. All statistics indicated support on the part of the state's citizens for children's programs. The findings of this survey can be reduced to a single sentence: "Connecticut citizens across a broad spectrum are profoundly concerned about children and they are willing to invest more of their own money--through taxes--to help them." (EV) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** U.S. DEPARTMENT OF EDUCATION Office of Educational Research and Improvement EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) VitThis document has been reproduced as received from the person or organization originating it 0 Minor changes have been made to improve reproduction quality. ;,'


e15057 Background: Gastric cardia cancer is one of the most common malignancies in Henan, China. Surgery is currently considered as the treatment choice for gastric cardia adenocarcinoma(GCA), Postoperative nutritional support was shown to reduce the incidence of complications and to shorten the length of post operational hospital stay. Recently, early enteral feeding (EEN) has become a standard nutritional support after gastrointestinal surgery. However, the impact of EEN on the immune function of postoperative GCA patients has not yet been elucidated. In this prospective study, we assessed immune function of GCA patients who had undergone surgery according to the postoperative nutritional method between EEN and TPN, and compared the complications and the length of stay of the two modes. Methods: 150 cases of GCA patients were randomly divided EEN group of 80 patients and TPN group of 70 patients. All the patients were given isocaloric and isonitrogenous nutritional support starting the day after operati...


Interactions between cells of the immune and metabolic systems play critical roles in controlling immune responsiveness and metabolic health. When these interactions are dysregulated, metabolic diseases such as obesity or lipodystrophy may develop. We have focused on cellular processes related to autophagy, a cellular self-degradation process, in controlling interactions between the immune and metabolic systems. In this study, we analyzed mice with an adipocyte-selective deficiency in PIK3C3/VPS34, a key early player in autophagy. These animals showed reduced white and brown adipose tissue (WAT and BAT) with enhanced macrophage infiltration, systemic immune activation, and spontaneous insulin-resistance. The phenotype of these animals bears a striking resemblance with the disease manifestations seen in individuals with lipodystrophy. Mechanistically, we found that conditional Pik3c3-deficiency inhibits adipogenesis in both WAT and BAT by downregulating glucose uptake and fatty acid metabolism, and impairs the thermogenic function of BAT by downregulating the expression of key regulators (Prdm16, Ucp1, and Cidea). Upon acute cold exposure, Pik3c3-deficient mice became cold-sensitive under fasting conditions due to insufficient thermogenesis in BAT. In contrast, these animals exhibited blunted beige fat thermogenesis in subcutaneous WAT in response to administration of a b3-adrenergic receptor agonist. Collectively, our data demonstrate that PIK3C3 is a vital regulator of adipose tissue development, metabolically-triggered inflammation, insulin resistance, and adaptive thermogenesis. Hence, we identify PIK3C3 as a potential therapeutic target for metabolic diseases such as type 2 diabetes.


Shuichi Nos\'e opened up a new world of atomistic simulation in 1984. He formulated a Hamiltonian tailored to generate Gibbs' canonical distribution dynamically. This clever idea bridged the gap between microcanonical molecular dynamics and canonical statistical mechanics. Until then the canonical distribution was explored with Monte Carlo sampling. Nos\'e's dynamical Hamiltonian bridge requires the "ergodic" support of a space-filling structure in order to reproduce the entire distribution. For sufficiently small systems, such as the harmonic oscillator, Nos\'e's dynamical approach failed to agree with Gibbs' sampling and instead showed a complex structure, partitioned into a chaotic sea, islands, and chains of islands, that is familiar textbook fare from investigations of Hamiltonian chaos. In trying to enhance small-system ergodicity several more complicated "thermostated" equations of motion were developed. All were consistent with the canonical Gaussian distribution for the oscillator coordinate and momentum. The ergodicity of the various approaches has undergone several investigations, with somewhat inconclusive ( contradictory ) results. Here we illustrate several ways to test ergodicity and challenge the reader to find even more convincing algorithms or an entirely new approach to this problem.


Seventeen patients with prostatodynia (chronic prostatitis-like syndrome) refractory to conventional medical treatment were treated with electric acupuncture at a low-wave frequency. All of them had had a complicated clinical course and pelvic hypertonicity. This therapy was administered to mitigate the congestion of pelvic circulation, especially around the prostate. The clinical efficacy of longterm treatment was considered excellent in 30% and moderate in 70% of the patients, with an overall efficacy rate of 100%. Treatment with Chinese medicines and chemical agents could be withdrawn completely in 50% of the patients, treatment with chemical agents could be withdrawn in 30% of the patients, and the dose of either type of medication could be reduced in 20% of the patients. To examine whether the efficacy of electric acupuncture was related to the induction of cytokines we also examined the serum levels of INF-gamma, IL-1 beta and IL-6, but, no significant elevation of either of them was detected.


Sentiment Analysis refers to the problem of automatically determining the polarity of the opinion expressed by an author in a text. Two competing approaches to solve this problem are the classifier-based and resource-based approaches. The resource-based approach involves creation of dictionaries of lexical units of a language with their sentiment values and using these dictionaries for sentiment analysis of a text. This report covers the resource-based approach, including background work that led to the lexicons, a few case-studies covering the structure of the lexicons and the process of their creation, and recent developments, including those at IIT Bombay. The report concludes with several directions that can be taken in the future.


The purpose of this study is to stimulate the naturalist intelligence of early childhood through the introduction of the surrounding environment. The sample in this study was 10 children aged 5-6 years in group B in a kindergarten in Padang. This research uses a quantitative approach with a pre-experimental type and the design used is one group pretest-posttest. Data collection was obtained from observation and documentation, then the data was processed using paired sample t-test analysis techniques. The results showed that the introduction of the surrounding environment can stimulate the naturalist intelligence of children aged 5-6 years. This is known from the results of the paired sample t-test obtained, where the significance value of 0.025 is smaller than the error level of 0.05 (0.025 <0.05). Based on these results it can be stated that Ho is rejected and Ha is accepted which means the child's naturalist intelligence increases with the introduction of the surrounding environment.


2526 Background: Pheochromocytomas and paragangliomas are rare tumors of the adrenals and paraganglia, respectively. As many as 30% of pts harbor a mutation in the VHL, RET, NF1, SDHB, SDHC, or SDHD genes. Pts with SDHB mutations have the highest rate of malignancy, with more aggressive tumors occurring earlier in life and often in extra-adrenal locations. We report on 10 patients with pheochromocytoma or paraganglioma and mutations/polymorphisms in the SDHB gene treated with CVD.

METHODS
After controlling symptoms of catecholamine excess, all patients received cyclophosphamide 750 mg/m2 and vincristine 1.4 mg/m2 on day 1 and dacarbazine 600 mg/m2 on days 1 and 2, every 21 - 28 days.

RESULTS
SDHB mutations (8) or polymorphisms (2) were confirmed in all pts. A median of 18.5 cycles (range 7 - 41) was administered. Reductions in vincristine for neuropathy (median 10 cycles) and dacarbazine (median 6 cycles) for delayed marrow recovery were made in 6 pts. Tumor shrinkage was observed in all pts (12% - 100% by RECIST) resulting in one CR, 7 PR, and one yet to be confirmed PR. Responses were observed at all sites of disease including liver, lungs, retroperitoneal nodes, and bones. Median time to response was 338 days. Median duration of response was >299 days (range 30 - 1092 days). One pt who had received radiation therapy and had an undefined congenital disease developed a secondary leukemia and died in a PR. FDG PET/CT imaging demonstrated continued reduction in SUVmax values in 26/30 lesions from a median SUV >25 to <6 over a median time >825 days as treatment was administered providing evidence of continued drug efficacy during prolonged administration.

CONCLUSIONS
CVD therapy has a very high level of activity in pts with pheochromocytoma/paraganglioma harboring SDHB mutations/polymorphism. Chronic therapy over prolonged periods of time resulted in continued tumor shrinkage. These results suggest that in pts with metastatic SDHB-related pheochromocytoma/paraganglioma CVD, an effective therapy with continued tumor shrinkage over a prolonged time, should be a part of their initial management.


The invention relates to an elevator system (1, 1') which comprises a safety device (2), by which a rotation and/or translation of the fixed bearing part of a rotary bearing of a deflection roller (7), which is associated with a counter-weight (5), can be detected for a supporting means (6) in order to support an elevator car (3). An alarm signal is generated by the safety device (2) when the position deviates from a predeterminable value.


Nonfermentative Gram-negative bacilli were commonly isolated from clinical material in a Malaysian hospital over a two year period of study. Pseudomonas aeruginosa, Acinetobacter sp and other pseudomonas were the most common organisms seen. Although these bacteria occurred regularly in clinical specimens their pathogenetic role could be established in only a small proportion of cases. Most of these organism were either contaminants or commensals of the normal bacterial flora. It is important to interprete the isolation of a nonfermentative Gram-negative bacillus with caution, and in the light of clinical findings. Failure to do so may result in the unnecessary use of antibiotics.


Microbiological contamination restricts the shelf life and degrades the quality of milk. Pasteurization usually kills contaminating microorganisms in milk but in the absence of appropriate food safety practices, its safety could be compromised. This study aims to evaluate the influence of food safety practices, aside from pasteurization, on the microbiological quality and shelf life of kitchen-pasteurized, flavored carabao's milk. Careful observation of the pasteurization process and revision of the process flow diagram was made. Milk samples were tested for pathogenic microorganisms (E. coli and Salmonella sp.) and its the microbiological shelf life was assessed though monitoring of aerobic, coliform, and psychrotrophic plate counts. Results of this study showed that without any improvements on the food safety practices, pasteurized, flavored carabao's milk could be contaminated with Enterobacter sp. and Bacillus sp., as identified through 16s rRNA gene amplification. Thus, pasteurized milk was unfit for consumption. On the other hand, the pasteurized, flavored carabao's milk with improvements on the food safety practices came out negative for E. coli and its estimated shelf life was set to 8 days. No Salmonella spp. was detected in both batches. This study shows that not only pasteurization, but also proper food safety practices are important in order to produce safe milk. *Corresponding Author: Bryan Rey R. Oliveros  firstname.lastname@example.com Journal of Biodiversity and Environmental Sciences (JBES) ISSN: 2220-6663 (Print) 2222-3045 (Online) Vol. 13, No. 6, p. 66-73, 2018 http://www.innspub.net J. Bio. Env. Sci. 2018 67 | Oliveros et al. Introduction Milk is a nutritious food consumed by many around the world. Today, highest production of milk comes from cows, but buffalo milk is not far behind. China is the leading producer of buffalo milk and then followed by India (Khedkar et al., 2015) . In the Philippines, buffalo is locally known as carabao and heightened investment on its production, milk, and milk products was seen since the creation of Philippine Carabao Center in 1992 ("Philippine Carabao Center," n.d.) As of July 2018, the total carabao inventory of the country is 2.88 million heads (PSA, 2018). Aside from its meat, carabao's milk is also widely marketed in the Philippines. It is a good alternative to cow's milk especially in tropical countries like the Philippines. Pasteurization is one way by which carabao milk processors improve the safety and lengthen the shelf life of their product (Smigic et al., 2012). Some processors resort to kitchen-type pasteurization due to financial difficulties. Unlike the conventional methods of pasteurizing milk, this one does not require any machines but only ordinary kitchen equipment and utensils in processing the milk. The problem with this type of pasteurization is that, without careful attention to proper food safety practices, microbial contamination of the milk is very imminent, and the quality, safety, and shelf life of the product could be compromised. Food safety practices are essential in any type of food processing activities. In the recent years, increased importance has been given to the effective application of current Good Manufacturing Practices (cGMPs), Sanitation Standard Operating Procedures (SSOP), and Hazard Analysis Critical Control Point (HACCP) (Flores-Miyamoto et al., 2014). For small milk processors, the financial cost of implementing these Food Safety Programs is a hindrance. On the other hand, production of safe food is still possible with careful attention to proper application of food safety practices in the process flow. This study aims to evaluate the effect of food safety practices on the microbiological quality and shelf life of kitchen-pasteurized, flavored carabao's milk. Materials and methods Improvement of kitchen-pasteurized, flavored carabao's milk process flow diagram The dairy facility for carabao's milk and milk products located in Los Banos, Laguna was visited and a copy of the process flow diagram for the pasteurized, flavored carabao's milk was procured. The entire process for its manufacturing was observed and notes were made on the possible improvements to be made. Thereafter, a meeting with the dairy facility personnel was set and the proposed improvements of the process were discussed and applied (Fig. 1). Sample preparation Two batches of pasteurized, flavored carabao's milk were made. The first batch was prepared employing the procedure before the improvement of food safety practices, herein referred to as pasteurized, flavored carabao's milk-A (PFCM-A). The other batch was prepared employing the procedure with improved food safety practices, herein referred to as pasteurized, flavored carabao's milk-B (PFCM-B). All packaged samples of PFCM-A and PFCM-B were kept in separate coolers filled with ice and were transported immediately to the laboratory. The samples were kept at 4C in a refrigerator until further use. Two runs of each batch were made. Sample enrichment and detection of Escherichia coli Enrichment and detection of E. coli in PFCM-A and PFCM-B were done according to the methods of Ombarak et al., 2016. Briefly, 10 mL of the milk was homogenized in a stomacher-blender with 90 mL of tryptic soy broth (TSB) and was incubated at 37°C for 16 h with shaking. After incubation, a loopful of the TSB was streaked onto eosin methylene blue agar (EMBA) plates and these were incubated at 37C for 18–24 hours. After the said period, presumptive colonies (blue-black with a metallic green sheen) from each EMBA plates were picked, streaked onto tryptic soy agar (TSA) and were incubated at 37°C for another 24 hours. J. Bio. Env. Sci. 2018 68 | Oliveros et al. Gene amplification 16s rRNA gene amplification was done to identify the putative identities of the isolates in EMBA plates. The template was prepared by picking a single colony and resuspending it in 0.2 mL ultrapure distilled water. After resuspension, 24 μL lysing reagent was added and it was allowed to stand for 10 min at ambient temperature. It was then placed in a boiling water bath for 10 min. Then, it was allowed to cool down and was centrifuged for 10 sec in the microfuge at 3000 rpm. Ten-fold dilution was made (10 μL cell lysate + 90 μL ultrapure distilled water) and 5 μL of that dilution was used as PCR template. The primers used were FC27 (5' AGAGTTTGATCCTGGCTCAG 3') and RC1492 (5' TACGGCTACCTTGTTACGACTT 3'). The PCR tubes were loaded in the thermal cycler (TPersonal, Biometra, Goettingen Germany) programmed with the following parameters: initial denaturation was done at 95°C for 5 min, followed by 30 cycles of denaturation (94C for 30 sec), annealing (55°C for 30 sec), extension (72C for 1 min), and final extension at 72C for 7 min. 16s rRNA gene sequencing PCR products from the 16s rRNA gene amplification (1.5 kb) were visualized by gel electrophoresis in 1% agarose gel at 100V for 30 min followed by staining in ethidium bromide solution and UV illumination (UVP Inc., Upland CA USA). The molecular weight standard 1 kb plus DNA ladder (Invitrogen Life Technologies, Inc.) was included in the gel. PCR products were sent to 1st BASE Pte Ltd, Singapore for DNA sequencing. Prior to sequencing, the PCR products were cleaned up using Spin Column Purification. Sample Enrichment and Detection of Salmonella sp. Enrichment and detection of Salmonella sp. in PFCM-A and PFCM-B were done according to Andrews, et al., 2018. Briefly, 25 mL of the milk sample was aseptically transferred into an Erlenmeyer flask containing 225 mL sterilized lactose broth (LB). It was then covered with a cotton plug and was incubated at 35°C for 24 hours. After the incubation period, 0.1 mL of LB was inoculated into 10 mL Rappaport-Vassiliadis (RV) medium and another 1 mL LB was inoculated into 10 mL tetrathionate (TT) broth. RV medium was incubated at 42 ± 0.2°C for 24 ± 2 h while TT broth was incubated at 35 ± 2.0°C for 24 ± 2 h. After the said period, RV medium and TT broth were streaked onto plates of bismuth sulfite agar (BSA), xylose lysine desoxycholate agar (XLDA) and hektoenenteric agar (HEA). Thereafter, plates were incubated for 24 ± 2 hours at 35°C. Microbial Shelf Life Determination of Pasteurized, Flavored Carabao's Milk In determining the microbial shelf life of PFCM-A and PFCM-B, monitoring of the aerobic plate count (APC), psychotropic count (PC), and coliform count (CC) was made every 2 days for 14 days. For APC and PC, 1 mL of the milk sample was serially diluted up to 10-4 into 9 mL peptone water. All dilutions were pourplated using plate count agar (PCA). After pour plating, APC plates were incubated at 37°C for 48 hours while PC plates were incubated at 4°C for 7 days. Quantification of coliforms count (CC) was similar with APC and PC but violet red bile agar (VRBA) was used. After pour plating, CC plates were incubated at 37°C for 24 hours. Five samples per day, per run, per batch were tested. Statistical Analysis The colony forming unit (CFU) data were expressed as mean ± standard deviation. Results and discussion Conventional Detection of Salmonella spp. and Escherichia coli in Pasteurized, Flavored Carabao's Milk Salmonella contamination could be introduced in various ways such us through infected cows, contaminated milking equipment, and even through contaminated water (Poppe, 2011). J. Bio. Env. Sci. 2018 69 | Oliveros et al. Table 1. Detection of pathogenic microorganisms in pasteurized, flavored carabao's milk at day 0. Carabao's milk Microbial parameters Presumptive E. coli Presumptive Salmonella sp. PFCM-A + PFCM-B (+) present; (-) absent. Table 2. Putative identities of the isolates from PFCM-A for the forward primer (27F) aided by sequence analysis using BLASTN. Isolate Putative identity (species level) % Homology 2 Enterobacter cloacae 97 3 Enterobacter cloacae Enterobacter xiangfangensis Enterobacter hormarchei 98 5 Bacillus cereus Bacillus thuringien


The present invention provides a lightweight wear-resistant bicycle tire, wherein the rubber materials of the lightweight wear-resistant bicycle tire tread contain, by weight, 25-40 parts of a SCR-10 nature rubber, 30-50 parts of a BR-9000 cis-polybutadiene rubber, 25-40 parts of a EPDM5508 ethylene propylene diene monomer, 60-80 parts of N220 carbon black, 2-4 parts of a SA hard resin, 1-3 parts of 3205 paraffin, 3-6 parts of a 1102 resin, 3-6 parts of ZNO-801 zinc oxide, 2-5 parts of a D-24 processing aid, 20-30 parts of P-150 processing oil, 1-3 parts of INS insoluble sulfur, 1-2 parts of an accelerator NS, and 0.2-0.5 part of an accelerator TT. According to the present invention, the tire tread achieves the perfect integration of light weight, comfort and wear resistance, wherein the riding resistance is reduced through the light weight so as to provide the high comfort, the service life of the tire is increased through the wear resistance, and the use performance of the tire is improved.


Research and operational activities, performed by Nuovo Pignone in co-operation with Snam, on development and testing of dry low-NO x combustors for a 10 MW gas turbine, are presented. The subject of this activity is a variable geometry premixed combustion system, that has been installed on two existing PGT-10 gas turbines, operating as prime movers in gas compressor stations. This new combustion system obtains a substantial NO x reduction, compared to standard combustors with diffusion flame


The various forms of corrosion are discussed and the role of localized electrochemical reactions in the wear of sliding surfaces are considered. It is stated that there is evidence that fretting corrosion, stress corrosion cracking, corrosion fatigue, and erosion corrosion have as a common basis the localized electrochemical reactions caused by a combination of the induced homogeneity of the surfaces and the corrosive environment. Several processes leading to erosive wear are discussed.


Libraries Build Communities is a VISTA project focusing on improving the educational & economic opportunity of residents in Prince of Wales Island and Kake while also improving the sustainability of libraries in these communities.


SUMMARY The effect of cinnarizine on motor function in Parkinson's disease was evaluated in a randomised double-blind parallel study of 20 patients. Both groups were comparable in age, duration of the disease, dose of levodopa and degree of disability. A significant worsening of mobility was observed in patients treated with cinnarizine (75 mg bd), whilst no change was recorded in patients receiving placebo. Cinnarizine should be added to the list of drugs capable of aggravating Parkinson's disease. consists of a randomised double-blind parallel design during a 3 month period. After an initial basal clinical were randomly divided in two halves and assigned to one of the two treatment cinnarizine bd and Group II, placebo tablets of iden- tical presentation twice a day. Throughout the trial no change in the underlying antiparkinsonian allowed.


The research paper, investigation is to locate out how to properly size and place non-dispatchable sources in distribution network. Employing the penalty function approach, a solar photo-voltaic system is studied as a distributed generator for reduction of energy loss and contains node voltage within the limit. To solve the issue, methods such as grey wolf optimization and particle swarm optimization have been used. The problem under consideration is examined on IEEE-33 bus distribution network. The outcomes of particle swarm optimization and grey wolf optimization are contrasted, and the simulation findings for the examined planning problem are encouraging.


Studies of electron density distributions through the Compton effect exploit the Doppler shift that occurs because the target electron. bound in a potential, must be moving. This phenomenon was first exploited by DuMond and co-workers within a decade of Compton's discovery,then hugely forgotten for thirty years. After a patchy renaissance it has acquired a new potency with the availability of synchrotron radiation. In particular the ability to produce high fluxes of circularly polarised x-rays has led to studies of the spin density in ferromagnets. Magnetic Compton scattering experiments provide the only direct probe of the bulk ground state spin density distribution in ferro/ferri-magnetic materials. They are often sufficiently characteristic of the element that site-specific contributions can be extracted and conduction electron polarisation studied; such work is the focus of this paper.


I study (for the first time) the dependence of M_D and of the leptonic decay constant f_D on the variation of the running charm quark mass m_c(\nu). I conclude that the present data on f_{D_s} from D_s into \mu\nu decay give a weaker constraint than M_D, where the latter leads to the result, m_c(M_c)=(1.08\pm 0.11) GeV, to two-loop accuracy in the {MS}-bar scheme, in good agreement with the value m_c(M_c)=(1.23^{+0.04}_{-0.05}) GeV extracted directly, within the same approximation, from M_{J/\psi}. The agreement of the corresponding perturbative pole mass with the one extracted directly from the data can indicate that the non-perturbative effects to the pole mass are negligible. Inversely, injecting the average value of m_c(M_c) from M_D and M_{J/\psi} into the m_c behaviour of f_D, I obtain f_D\simeq (1.52\pm 0.16)f_\pi, which combined with the sum rule prediction for f_{D_s}/f_D, gives f_{D_s}\simeq (1.75\pm 0.18)f_\pi in good agreement with the data. The extension of the analysis to the case of f_B and f_{D^*} is discussed.


I just reread Berman Hudson's fine article on concepts of mapping and interpretations in the Fall 1990 issue of this publication (Hudson, 1990). I have noticed a follow-up article and a letter (Shellentrager, 1990; Byrd, 1991). Berman Hudson seems to have struck a nerve or two. His statement on page 71, "The obsession with map unit variability and taxonomic purity are the result of conceptual not technical deficiencies," summarizes my thoughts. As Berman implies on page 69, the field soil scientists and the novice users seem to have much less difficulty in using and justifying the continued use of published soil surveys than do the University Ph.D. 's and the GS-13 and up soil scientists. One of my concerns is that the new generation of field soil scientists will know all about statistics and computers, pit examinations and such, but little about soils-landscapes and landforms. They can read computer programming language but can't read a landscape or aerial photograph. I suppose the days of walking across a landscape with only a probe and mapboard are gone. The plane table mapping of the 1930s is gone and good riddance, but somehow the addition of statistical justification seems a major departure, not another better tool as was the aerial photo. If our young soils scientists don't learn to tentatively classify a soillandscape in their mind, check their hypothesis with a probe and illustrate this as a map, then the art of soil mapping is lost. The science of soil mapping will remain because given enough time, enough probing, a big enough scale, and a knowledge of soil taxonomy, any average college soil judger can produce a taxonomically correct soil map. The art of producing a soil map mainly involves knowing what to leave out as well as what to put down. An artful soil mapper will have in mind the map user when he decides what to leave out. A scientific mapper will try to put it all down and justify every line statistically and will wind up with a legend as thick as a phone book. Then a correlator will have to prune away at the legend using whatever whims are the current rage in those circles. The better correlators will prune away using an artful approach if they intend to help the survey users. There's plenty of science in soil science and soil mapping, but let's not crowd out the "art of soil mapping." "The older surveys are better than the newer ones." I repeat a saying I've heard many times. They're not as taxonomically correct and the base map is out-of-date, but the mapper had a user in mind. Usually this was a farmer or farm planner and the first criterion was the land capability class,


Japan has a good relationship with the European Union trough many channels. The EU donates two times more for ODA than what the USA does. Regarding the GNP, the EU's GNP is almost as big as the USA. The EU is representative almost as an additional member at the G7. It has proven that even small and middle-sized countries, when united, can play an impressive role for international politics. Flow of refugees and migrants into the EU makes the political situation in the EU unstable. Brexit will weaken further the EU. That has a negative impact on Japan. If Japan cooperates with the EU, Japan can contribute much more for peace and security for the world. This is possible because Japan and the EU with soft power have won trust and respect in the world community. To make this world more peaceful is the best way to curve nationalism and populism at home. For better understanding the important role of the Japan and the EU relationship, one needs only to imagine how this world would be if there is neither Japan nor the EU and if only America, China and Russia determine everything.


this paper introduces a new approach for modeling of company's behavior based on support vector data description (SVDD). Using SVDD behavior of all companies surrounded by hyper sphere in high dimensional space. We encountered appropriate observation from experimental results.


This research focuses on the design and development of a subsystem for handling ill-formed input in an intelligent tutoring system. For this purpose, I built the Ill-Formed Input Handling System (IFIHS).
The IFIHS system is designed for understanding ill-formed natural language input from first year medical students. The IFIHS system consists of a screen manager, spelling corrector, parser, and understander. The IFIHS system is implemented on a Xerox 1108 AI Machine in the Interlisp-D language. Fast response time and user friendliness were the most important considerations in the design.
The screen manager provides a full screen editor and input tracer for an easy editing capability for the student. I made the screen manager as simple as possible because most medical students have little computer experience.
My spelling correction program can handle most kinds of spelling errors including character case, order reversal, missing characters, added characters, and character substitutions. This spelling correction system also corrects unexpected abbreviations and word boundary errors without making extra lexical entries. This spelling correction system can detect most student spelling errors and correct them automatically.
We stored the lexicon in a trie for fast searching. Each lexical entry contains orthographic, syntactic, and semantic information so that the system can retrieve information for both spelling correction and the parser/understander at the same time.
The LFG parser and the understander are designed to handle most types of simple sentences, and some kinds of fragments, ellipses, anaphora, and semantic corrections. The LFG parser produces the c-structure and f-structure for each input sentence in turn. The understander produces the logical form using the f-structure and the dialog history, and passes the logical form to the controller of the intelligent tutoring system.


Scaling transistors and following Moore's law have served the industry well for more than 50 years in providing integrated circuits that are denser, cheaper, higher performance, and lower power. And despite occasional reports of its demise, Moore's law is alive and well. But progress in scaling CMOS has not come easily. We've had to continually invent and introduce new materials and new device structures to deliver the performance, power, and cost improvements expected of each new technology generation. This article describes trends in CMOS scaling over the past decade and discusses some of the new device options and technology directions being explored to continue scaling into the future.


Streptococcus mutans and Streptococcus mitior were both capable of colonizing the surfaces of human teeth in an artificial mouth. Although fermentable carbohydrate was not essential for colonization, highest numbers were recovered after 5 d if 5–0°***0 (w/v) sucrose had been available intermittently. When grown together in mixed culture the interaction of the two species was affected profoundly by the available nutrients. In the presence of synthetic saliva alone, Strep. mitior was strongly antagonistic to Strep. mutans. When a nutrient broth containing sucrose was also provided intermittently there was slight inhibition of Strep. mutans accompanied by an increase in the proportion of Strep. mitior in the plaque, although the former was the dominant organism under these conditions. When 0–5% (w/v) glucose replaced the sucrose, mutual antagonism occurred and fewer organisms were recovered than if only synthetic saliva had been available. One reason why a high-sucrose diet encourages colonization by Strep. mutans may be that insoluble extracellular polysaccharide confers a competitive advantage upon it in the face of antagonistic agents such as the hydrogen peroxide produced by Strep. mitior.


But, says President Allen, academic freedom involves duties as well as rights. I agree: duties that the whole community owes to the students, who must after all be the focal point of every discussion of teaching and learning. Students cannot learn except by a conflict and opposition of ideas. Unless the thinking presented to them for scrutiny has several dimensions, they cannot form their own intellectual synthesis. The great tradition of our people is the tradition of non-conformism not for the


In the new era, teaching concepts are updated rapidly, and cultivating core competencies and values have become the main teaching concept. The design of senior high school biology classroom activities should focus on the concept of core competencies and values, consider the needs of cultivating students' core competencies and values, and enrich teaching contents. The connotation of core competencies and values is analyzed in detail in the paper. The exploratory, intuitive, problematic as well as biological experiment classroom activities of senoir high school biology are designed according to the core competencies and values. Senior high school biology teaching is very important for shaping the values and outlook on life of senior high school students. Concept of core competencies and values is applied in the design of classroom activities to optimize the biological classroom teaching environment, realize the combination of teaching contents and life, improve the efficiency and quality of education, and truly reflect the value of education. 1 The Connotation of Core Competencies and Values The teaching concept of core competencies and values has emerged in recent years. Students' quality, learning foundation, learning ability and interest are included in the teaching indicators to meet the individual development needs of students. The core competencies and values of biology in the new curriculum standard include concept of life, scientific thinking, scientific inquiry and social responsibility. In the learning process, a correct view of life is formed, and the character and ability of paying attention to personal and social development are cultivated . In biology teaching in senior high school, it is embodied in leading students to understand biodiversity, summarize the laws of life, think deeply with the concept of life, gradually develop the reasoning and deductive way of thinking, dialectically solve difficult problems of biology, become interested in unknown things, try to interpret the laws of life, and establish a natural view with strict logic . Concept of core competencies and values plays a guiding role in the design of senoir high school biology classroom activities. The design of classroom activities is based on the biological law to find out the existing biological contradictions, put forward and solve problems pertinently, study and demonstrate difficult problems, give scientific and reasonable explanations, and apply them to practice for verification in order to connect biology with life closely. 2 The Design of Biology Classroom Activities in Senior High School under the Concept of Core Competencies and Values 2.1 The Design of Exploratory Classroom Activities Understanding and interest are the most important for senoir high school students in learning biology courses. Teachers should pay more attention to students, understand them, design exploratory classroom activities in a reasonable way according to the textbook content, encourage students participate in classroom activities with a positive attitude, stimulate students' learning enthusiasm, and enable them to participate independently. Teachers should construct appropriate classroom situations. The design of introduction of classroom teaching should evoke students' interest and visualize the originally abstract biological knowledge . Teachers should play a good guiding role to lead students to think about problems, gradually form a deep understanding, and train students in biological thinking. For example, in the 2019 9th International Conference on Social Science and Education Research (SSER 2019) Copyright © (2019) Francis Academic Press, UK DOI: 10.25236/sser.2019.264 1339 "introduction to auxin", the teacher can design experimental operation activities of corn germination for students to observe and think about the experimental situation independently, compare and record the growth characteristics of corn coleoptile in different environments to form their own understanding, record the growth situation in detail, and let them conduct independent analysis. In the following classroom teaching, multimedia is used to present students' records. The teacher analyzes and supplements the growth characteristics of the corn coleoptile in detail, allowing students to find their own analytical deficiencies, and guiding them to analyze problems from a biological perspective and form a preliminary understanding so as to help them establish biological thinking. In this exploratory classroom activity, students can draw conclusions from practice, learn to explore and think independently. They will actively communicate with each other, understand each other's views, and realize the meaning of life. In the experiment, the growth law is summarized, and students are allowed to recognize the biological laws . The teacher leads students to explore the magical biological world, which is conducive to cultivating students' outlook on life and values. Reasonable design of exploratory classroom activities can enable students to have a deep understanding of biological knowledge, grasp the difficulties and key points of teaching, and realize the humanistic connotation behind the classroom, which plays an important role in the cultivation of students' ethical attainments . 2.2 The Design of Intuitive Classroom Activities Teachers should set clear teaching objectives, rationally use teaching resources to organize biology teaching classes, clarify the direction of teaching, and create vivid classroom situations. In the teaching of more abstract knowledge points, teachers can construct an intuitive teaching framework. Difficult knowledge points should be presented to students through examples and simulations to deepen their impression, facilitate their understanding and memory, and create a good learning environment . For example, the relationship between insulin and regulating blood sugar balance is a key and difficult point in the teaching of "blood sugar regulation". If students do not understand it, they will easily be confused when memorizing. The teacher can explain the prevention and harm of diabetes mellitus to students, show them some collected data in recent years, let students understand the causes of diabetes mellitus and the significance of prevention and treatment through practical cases, improve students' biological core competencies and values, guide them to form rigorous scientific consciousness, and promote their comprehensive development. 2.3 The Design of Problematic Classroom Activities Senior high school biology is a difficult subject. It is impossible to grasp biological knowledge only by memory and recitation. It requires students to truly digest and absorb it. In the traditional teaching mode, teachers explain knowledge points and, like a porter, deliver them to students rigidly. Students accept passively, and unable to truly understand the problem. In order to improve core competencies and values of students, senior high school biology teachers should design problematic classroom activities to train students' individual thinking . Teachers should consider students' interests and needs in the design of biology classroom activities make students master relevant curriculum knowledge according to teaching objectives, skillfully design biology problems, and link life with teaching. For example, during the explanation of "protein", students are unfamiliar with the new knowledge point. The teacher should set up biological problems in combination with actual life. The content of the problem should be combined with real life . Teachers can put questions such as "Poisoned milk powder with melamine has a serious impact on children's body. What makes children have kidney stones?" Or "Recently, the incident of big-headed children appeared in the news has aroused widespread concern in society. How to explain it with biological knowledge?" Based on questions raised by the teacher, students collect information, understand the background of the news, and analyze questions with biological knowledge. In the next class, students are required by the teacher to show the collected biological materials through lectures. They are guided to discuss and communicate in class. The teacher explains the problem based on the knowledge of protein, and students' biological thinking is effectively trained, their self-directed learning consciousness is cultivated, and the cultivation of core competencies and values is better realized.


The characteristic of lesions of oral mucous membrane in different diseases of organs and systems in children is presented in the article. The clinical symptoms, principles of treatment of these diseases in pediatric practice are considered.


A current sense amplifier includes a high-side current sense amplifier and a low-side current sense amplifier. The high side current sense amplifier provides a current sense Voltage signal for use with a Voltage regulator and generates the current sense Voltage signal responsive to a first current sensed through a high-side Switching transistorina first mode when the high-side Switching transistor is turned on and the low-side switching transistor is turned off. The high-side current sense amplifier generates the current sense Voltage signal responsive to a second current through the low-side Switching transistor in a second mode when the low-side Switching transistor is turned on and the high-side Switching transistor is turned off. The low-side current sense amplifier senses the second current through the low-side Switching transistor and generates a current control signal to the high side current sense amplifier in the second mode.


Introduction. In addition to the "Classical" Risk Factors (RF) for Arterial and Venous Thrombosis, some authors, as triggers for the development of the latter, refer to reactive changes in Peripheral Blood (PB) counts and markers of Hereditary Thrombophilia. The results of most studies indicate that the "Classical" Risk Factors (RF) for Vascular Thrombotic Episodes are strong triggers of their development, the presence of which eliminates the Pro-thrombogenic potential of carrier of the Hereditary Thrombophilia and reactive changes in Peripheral Blood (PB) (RChPB). However, to date, there is no data regarding the assessment of contribution of the Leiden Mutation in the cohort with both reactive changes in Peripheral Blood (PB) and Risk Factors (RF) for Thrombotic Complications (ThC).
Results. In patients with reactive changes in the Peripheral Blood (PB), the Leiden Mutation occurs in 5,92% of cases (9 carriers). In individuals with Thrombotic Complications (ThC), the Allele G1691A of the Proaccelerin Gene is determined more often than in a cohort without them (5 out of 31 vs 4 out of 121; p=0,030). In the general cohort of individuals with reactive changes in Peripheral Blood (PB), carriage of the Leiden Mutation increased the risk of Thrombotic Complications (ThC) by 3,05 times (Relative Risk (RR) = 3,05; 95% Confidence Interval (CI) = 1,54-6,03). In patients without Risk Factors (RF) and people under 60 years of age, Thrombosis occurred more often with the Nucleotide Variant of Allele G1691A of the Gene V of Coagulation Factor than with the Allele of wild-type (3 out of 6 vs 4 out of 75; p=0,007 and 4 out of 6 vs 8 out of 107; p=0,010, respectively). The probability of developing of Thrombosis with carriage the Allele G1691A of the Proaccelerin Gene in patients with Thrombotic Complications (ThC) without Risk Factors (RF) and in younger patients was 10,57 (95% Confidence Interval (CI) = 2,60-42,87) and 16,83 times (95% Confidence Interval =3,43-82,41), respectively. The risk of Thrombotic events in people without Risk Factors (RF) younger than 60 years is 16,75 times (Relative Risk (RR) = 16,75; 95% Confidence Interval (CI) = 3,44-81,50). However, the frequency and risk of Thrombosis did not increase in individuals with Risk Factors (RF), in patients over 60 years of age or in a cohort with Risk Factors over 60 years of age.
Conclusion. Carriage the Allele G1691A of the Gene V of Coagulation Factor in patients with reactive Thrombocytosis, Leukocytosis and Secondary Polycythemia increases the risk of Thrombosis primarily due to patients without Risk Factors (RF) younger than 60 years.


A wideband auxiliary receiver embeds a band-reject N-path filter in the low-noise amplifier to improve the compression point. The receiver has high input impedance and it can be placed at the transmitter output without loading effects. Implemented in a 28nm CMOS technology it occupies 0.12mm2 active area and it can withstand up to +4 dBm QPSK modulated 20 MHz signal with less than 1-dB noise degradation at 50 MHz offset, achieving an equivalent −171 dBc/Hz noise-to-carrier ratio at 1 GHz. Operation was experimentally verified between 0.7 and 2 GHz. The signal path draws 9 mA from a 1.8 V supply and the clock generation circuits draw 16 mA from a 1.2V supply at 1 GHz.


The timed up and go (TUG) test is commonly used to measure functional ability in a variety of patient populations. However, improved assessment of function could be attained with the addition of kinetics during the TUG test. A longitudinal, repeated measures evaluation of 12 osteoarthritic patients, set to undergo TKA and 12 control subjects was conducted using the TUG test pre-TKA and six months post-TKA. Kinetic variables during stance and push-off, collected from two forces plates, and time to completion for the TUG test were examined. Separate one-way, repeated measures ANOVAs were completed to examine change over time in each dependent variable. Data from both subject samples were combined, revealing significant correlation between TUG time to completion and loading rate (p=0.000, r=-0.795), anteroposterior maximum ground reaction force (p=0.000, r=-0.753) and contact time (p=0.000, r=0.882) during both time periods. There were significant increases in loading rate (p=0.023) and significant decreases in TUG time to completion (p=0.016) and contact time (p=0.013) in TKA subjects at six months. Significant main effects were reported between TKA and control subjects for loading rate (p=0.003), TUG time to completion (p=0.017), and contact time (p=0.007). Post-hoc analysis revealed TKA patients have a decreased loading rate (p<0.001), increased TUG time to completion (p=0.007), and increased contact time (p=0.004) when compared to controls prior to surgery. Based on these results, a decrease in time to completion may not only be due to an increase in walking speed post-TKA, but also the ability to load the limb more quickly upon standing. Therefore, a decrease in time to completion of the TUG test could indicate a better ability to accept weight and a greater overall function within the involved limb.


In previous communications (Hurst, 1948; Hurst, Peters, and Melvin, 1950) we have recorded the therapeutic action of Nitroakridin 3582 and compared those of penicillin, chloramphenicol, aureomycin, and terramycin against psittacosis and lymphogranuloma venereum in mice or in developing chick-embryos. For the past eight years we have used these experimental infections (among others) in routine screening-tests of synthetic organic compounds for antiviral properties, and during this time have encountered a number of quite dissimilar chemical types each exhibiting some degree of activity against these particular infections. The most active compounds were quinoxaline-l: 4-dioxide and various substituted derivatives, the best of which closely approached aureomycin in therapeutic potency. Alergant (1953) has confirmed this action in human lymphogranuloma, though toxic side-reactions rule out the possibility that the compounds will be useful additions to the pharmacopoeia. The quinoxaline oxides also manifest anti-amoebic and antibacterial properties (Jones, Landquist, and Stewart, 1953; McIlwain, 1943; Francis, 1953).


As is the case in other advanced liberalmarket economies, human resource management (HRM) in Australia has become an accepted 'managerial profession' with its own professional association and credentialism evident in specific education, training and professional networks (Armstrong 1986; Michelson and Kramar 2003). This chapter explores the origins and historical development of HRM in Australian workplaces throughout the twentieth century through to the present day. Despite its distance from the centres of economic activity in the United States and Europe, and its comparatively small economic footprint, Australia has played an important role in the historical development of HRM. This is a southern hemisphere, settler economy highly dependent on the export of resources, so one might suppose the predominant state of employee management to be relatively informal and derivative, and indeed this general summation is accurate for a significant component of the Australian economy. However, the history of HRM in Australia also reveals surprising levels of local innovation and global influence. Australia was after all the birthplace of the 'father' of human relations, Elton Mayo (Trahair 1984), and as this chapter reveals played a central role in the ongoing global spread of new management ideas and practices. The chapter reveals a complex picture of rapid changes in the practice of employment and personnel administration, work organisation, and industrial relations and collective bargaining. Examples of change and innovation operated alongside more traditional and informal methods and were shaped by broader factors such as changes in product and labour markets, patterns of government and state regulation, as well as the role of the labour movement, professional groups, and the changing values of industry leaders and business executives. While significant attention has been directed to the Australian system of compulsory state industrial arbitration and awards (see for example Dabscheck 1980; Patmore 1991), the impact on management practice is perhaps less pronounced than commonly supposed. Indeed, in establishing specific minimum standards of wages and working conditions, large residual areas of workplace activity were deemed the sole prerogative of management (De Vyver 1959). Contrary to popular opinion, this gave employers significant freedom in deciding how work was organised and employment managed over and above minimum standards. Most interestingly though, the Australian case provides a revealing insight into the global diffusion of management ideas and


Thermosets curing is a complex process and properties prediction for designers and users is delicate. This is crucial for thick composites since thermo chemical coupling becomes significant due to the exothermal aspect of the crosslinking reaction. The objective of this work is to present a numerical tool coupling the thermal, the chemistry and its effects on the formation of the matrix. Two stages are presented. In the first, evolution laws of the coupling problem, to be solved for the description of the matrix in formation, are presented. The taking into account of these laws in the Abaqus finite elements software is exposed in the second stage. Results are compared successfully with experimental measurements for two different thermosetting systems. This work opens the way to the residual stress state prediction at the end of the cure. Mots-clefs : couplages ; cuisson ; elements finis


This paper provides a name for a whitefly that occurs on diverse plants of economic importance. The insect is of concern in Florida, where it has been collected from numerous plants, including avocado, citrus, guava, and palm, and where it is suspected of being associated with the destructive lethal yellows disease of coconut palms. It is here recorded from 38 genera belonging to 27 plant families. Its known distribution includes southern Florida, portions of Central and South America, the West Indies, and the Canary Islands. Two previously described species are discussed briefly because of their close relationship to the new species. Harold A. Denmark, Chief of the Entomology Section, Division of Plant Industry, Florida Department of Agriculture, asked me to describe the new species, and I am happy to do so. Through his efforts. and those of his associate, Howard V. Weems, Jr., and of their Department Inspectors, much useful material has been collected in Florida since 1957. Specimens from other areas have accumulated over a period of nearly 60 years and have been furnished by many people. I extend my sincere appreciation to the collectors and to all persons who have contributed to this study. Aleurodicus coccolobae Quaintance and Baker (1913), Aleurodicus fiavus Hempel (1922), and Aleurodicus dispersus Russell, new species, are closely allied and form a group that is set apart from other species of Aleurodicus by the characteristics of its so-called "simple pores." Before discussing the species further, it is desirable to describe the wax secreting organs on the dorsal surface of the immature forms. Glands found in the pupae of Aleurodicus were called compound pores and simple pores by Quaintance and Baker (1913). Most subsequent workers have followed their terminology and it is, used here. Although the compound pores were well described by Quaintance and Baker, the simple pores have received little attention from them or other workers. Since both compound and simple pores vary, and are of value in differentiating the species under consideration, they are discussed in some detail. Compound pores occur in seven or fewer subdorsal pairs. They are comparatively large and conspicuously invaginated, and have several to many distinct loculi at the bottom, arranged in a circle around the base of a central process that rises above the top of the pore. Cylindrical, or cylindrical and thimble shaped, compound pores occur in the species treated here. In contrast, simple pores are fairly tovery numerous and occupy various positions. They are minute to small, are slightly or not at all invaginated, and lack well-defined loculi and an elongate central process. Though the structure of the pores is apparent only under optimum optical conditions, their size and location are readily discernible. Disk pores and their associated porettes, which are not included in the category of simple pores, are scattered sparsely in the median and submedian areas. The disk pores are very minute and have thin dark rims, and the porettes are nearly or quite indistinguishable. They appear to be similar to the pores and


In this paper, non-linear behaviors of structures with special moment resistant frame were studied and possibility of using knee bracing for retrofitting of those structures was examined. For this aim, the structures that have been designed according to the second edition of Iranian seismic code (2800), were selected. Those models have 3, 5 and 7 stories. To evaluating and retrofitting of models, non-linear static analysis and capacity spectra (ATC-40) method were applied and providing of the expected performance levels in FEMA356 was studied. Results showed that the response of structures that designed according to the previous edition of code (second edition) is not compatible with the criteria of third edition. The knee bracing system was used to seismic retrofit of those structures. It would be concluded that the using of knee bracing increases lateral stiffness and improves their energy dissipating capacity. Furthermore, the results showed that the shorter knees have the highest stiffness and ductility in the structures.


We fabricate multilayer graded-index circular core multimode polymer parallel optical waveguides using the Mosquito method by optimizing the needle scan program, and realize a high core-position accuracy with a 125-μm vertical and horizontal pitch.


Summary Physical-chemical composition and hygienic quality of milk are of crucial importance in cheese manufacturing. During 2007, a research was carried out with the aim to investigate manufacturing features and milk quality of Krk sheep and to describe technological procedure of manufacture and physical-chemical composition of Krk cheese. The milking capacity was checked according to AT method. Chemical composition was analyzed by infrared spectrometry and hygienic milk quality by fluoro-opto-electronic method, i.e. flow cytometry method. In 160 days of lactation, sheep produced in average 108 kg of milk (38 kg in lactating and 70 kg in milking period), 5.67 kg of milk fat and 4.12 kg of proteins. In the average, the milk contained: 19.49 % of dry matter, 8.29 % of milk fat, 5.99 % of proteins, 4.45 % of lactose and 11.32 % of dry matter without fat. Milking had a significant influence on: daily milk quantity, dry matter and milk fat share, milk freezing point and hygienic milk quality (log


Silver impregnations of nerve fibers and glia comprise a formidable number of long and tedious processes. Many of these methods give beautiful results, but, as they require secial fixatives or lengthy and tedious pretreatment, they are impracticable for use in the majority of laboratories where formalin is the routine fixative. Foot L 2 has obtained satisfactory glial impregnation in frozen sections after fixation in neutral formalin and, with his work as a starting point, I have endeavored to devise a method that would be applicable to paraffin sections as well. Using the silver diammino hydroxid recommended by Foot, 3. 4 as a result of his tests of the work of Kubie and Davidson 5 and his formol-sodium carbonate reducer, I experimented with paraffin sections after formalin fixation. The experiments induded application on the slide, before impregnation, of reagents advocated as sensitizers of glia to silver. Ammonium bromid,6 ammonium hydroxid,7 hydrobromic add,7 pyridin,3 Carnoy's fluid,8 and other reagents that have been of value in neurological methods were tried without success. Del Rio-Hortega's 9 results with formalin-uranium nitrate fixation preparatory to silver impregnation of frozen sections led me to precede silver impregnation of formalin-fixed paraffin sections by treatment with uranium nitrate. A differential reaction to silver was immediately apparent. There was no precipitate deposited on the slide and the sections showed argentation of the fibrillar elements; nerve fibers, fibrllar astrocytes, reticulum and collagen were impregnated. After uranium nitrate, silver staining was so intense that it became necessary to use the silver dianmino hydroxid at room temperature rather than at 50° C, and to reduce the time from 30 minutes to 20 seconds. Uranium nitrate in i per cent solution proved most satisfactory, but exposure of more than 5 seconds inhibited impregnation. The other nitrates were of no value. * Received for publication July I, '932.


INTRODUCTION AND AIMS
Microbial contamination of enteral feeding and infant formulas can result in a risk of worsening of the clinical condition of the patients, who are already weakened and susceptible to pathogens. The objective was to evaluate aspects of the management of quality hygienic - sanitary of enteral feeding and infant formulas in hospitals, focusing on the structure, process and outcome.

METHODS
An observational, descriptive, prospective, with quantitative and qualitative variables study was done. The survey was conducted for 12 months and 227 samples of enteral feeding and 176 of infant formula were collected in Nutrition and Dietetic Services of Health Secretary / Federal District. In evaluating the operating conditions, the Tool 2 was applied to: Enteral Nutrition Preparation. Data were analyzed from the unified Donabedian's triad for evaluation of health services.

RESULTS
The results obtained with the Tool 2 demonstrated that the Storage Block complies with legal requirements. Moreover, Dressing Block is a risk factor for the contamination. From the 403 samples, 56% corresponded to samples of Enteral Nutrition and 44% to samples of Infant Formulas. The data indicate that from 227 samples of Enteral Nutrition, 6.2% were in disagreement with the legislation, while from 176 samples of Infant Formulas, 4.6% were also in disagreement with the legislation.

CONCLUSION
The ineffective implementation of the sanitary and hygienic requirements during the preparation results in a microbiologically unsafe product to patients in debilitated health state, and the count of mesophilic microorganisms can be a good indicator of microbiological safety.


The infrared spectroscopic and thermodynamic properties of H bonding in a number of diol monoalkyl ethers RO(CH2)nOH and RO(CH2)2O(CH2)2OH where R = CH3, C2H5 and C4H9 and n= 2, 3 and 4 are rationalised in terms of their conformational and self-association behaviour in solutions. The half-band width Δtext-decoration:overlineν½ and the apparent integrated absorption intensity B= 1/Cl∫ ln(T0/T)text-decoration:overlineνdtext-decoration:overlineν of the intramoleculary H bonded OH bands and the enthalpy change ΔH° involved in the equilibrium reaction intramolecularly H bonded monomer ⇌ free monomer are linearly correlated with the shift of OH frequency on intramolecular H bonding Δtext-decoration:overlineν(=text-decoration:overlineνfree OH–text-decoration:overlineνH bonded OH). The nature of the self-associated species is found to depend no the stability of gauche conformations of the O(CH2)nO units.


Roentgenograms of the normal or pathologic contours and relations of blood vessels injected with radiopaque substances are useful for diagnostic, teaching, and research purposes. Many combinations of radiopaque substances and menstrua may be employed for this technique in cadavera or in experimental animals, depending on the results desired. The particle-size, viscosity, chemical nature of the radiopaque substance and menstruum, and the pressure used for injection, determine the caliber of the vessels which will be filled as well as the degree of hardness in the injection cast to allow subsequent clearing, dissection, maceration, or corrosion of the specimen. Many of the substances and injection methods used in such studies have been reviewed by Lum ( '46). A plastic (vinylite) dissolved in acetone has been used successfully for injecting blood vessels in human and animal tissues. This solution is not radiopaque, but it has many advantages not found in other injection masses. It may be colored with various fast dyes, can be used at room temperature, will penetrate into small vessels or body cavities, and sets rapidly into a hard cast of the injected area which will withstand dissection, bacterial maceration or chemical corrosion (Narat, Loef and Narat, '36; Puckett and Neumann, '40; and Ward's Natural Science Bulletin, '47).


Paper presents the theoretical and empirical research devoted to studying of features of social intelligence in structure of personal potential of first-year students. Interrelations of advanced social intelligence with individual and personal features of young men and women are revealed, compared and described.


Levels of obesity among children in the western world are increasing at an alarming rate. Between 1995 and 2003 obesity rates among children in the UK aged 2–10 years, for example, accelerated from 9.9 to 13.7% (Jotangia et al, 2006). The long-term implications on the nation's health and the burden it will cause to the NHS in years to come if it is not tackled effectively is already a cause of major concern. The British Medical Association (BMA, 2007), for example, estimate that there are already around 1 million obese children under 16 in England.


GMA-type acrylic resin was prepared with four kinds of monomers by free radical solution polymerization.The synthesis technology was optimized by orthogonal layout.The GMA-type acrylic powder coating obtained by the optimum technology showed excellent physical and chemical properties.


A digital pilot-symbol-aided Rayleigh fade compensation technique for coherent intersymbol interference-jitter-free offset quadrature phase shift keying (IJF-OQPSK) is proposed. Instead of a fixed valued pilot symbol sequence, a scrambled pilot symbol sequence is transmitted to measure, and therefore to compensate for, the Rayleigh fading channel. The bit error rate (BER) performance of this system is investigated in fast Rayleigh fading, additive white Gaussian noise (AWGN), and cochannel interference (CCI) environments by using computer simulation. The simulated results show that a 2.5 dB improvement is achieved over the differentially detected pi /4-DQPSK at a BER of 10/sup -3/. Unlike the differentially detected pi /4-DQPSK, the system does not have an error floor or residual bit error, provided that the frame length N is not longer than the upper limit of frame length, N/sub max/. Another significant advantage is that the proposed IJF-OQPSK modulated signal is shown to suffer less spectral spreading than pi /4-QPSK signaling over a nonlinearly amplified channel.<<ETX>>


The present invention provides an existing cable connector with improved durability as compared to a connector and a relay connector device as an inspection purposes. The guide member (40) with respect to the terminal holding member (20) along the longitudinal direction of the relative movement. When the main connector (11) is pressed to the last to the mating connector (801), the guide member (40) by a mating connector (801) of the proximal end face (814) pressed with respect to the terminal holding member (20) against the force of the spring (92) is retracted relative to the guide wall portions (41a, 41b) of the terminal (30) of the inclined portion toward the substrate (811) from the top side, terminal (30) toward the center and poured on the substrate (811) the electrode contact.


In this letter, a neural predictor-based dynamic surface predictive control framework, endowed with the merits of adaptive dynamic surface control and finite control-set model predictive control, is proposed where the estimation of neural predictor is incorporated to identify the system dynamics and lumped unknown uncertainties. The key features of the proposal are that, first, the issue of ``explosion of complexity" inherent in the classical back-stepping control is avoided, second, the model uncertainties and disturbances are explicitly dealt with, and, third, the tedious determination procedure of weighting factors is removed. These features lead to a much simpler adaptive predictive control solution, which is convenient to implement in applications. Furthermore, a Lyapunov function is constructed, and the stability analysis is given. It demonstrates that all signals in the closed-loop system are uniformly ultimately bounded. Finally, this proposal is experimentally assessed, where the performance evaluation of steady-state and transient-state confirms the availability of the proposed solution for modular multilevel converter.


the most important threat to livestock production worldwide. Efficient control of these diseases currently relies primarily on enabling strategies (i.e. rapid recognition of disease incursion, enhanced biosecurity to protect surrounding herds, disease control, and compensation and vaccination) to limit their spread. A prerequisite for better control of TADs is to rapidly detect and characterize the responsible agent. IAEA scientists develop molecular tools for better understanding of the epidemiology of capripoxviruses


The issue of a partial or total ban on the advertising of cigarettes and/or tobacco products has been the focus of substantial public policy debate for a number of years in several countries. As far back as the early 1970s, Hamilton carefully examined the effects of the ban on electronic media cigarette advertising imposed in 1971 in the United States and concluded that the advertising ban did not have a significant effect in reducing total demand for cigarettes. Bishop and Yoo, using a more complex econometric specification, also reached essentially the same conclusion. Hamilton also examined the demand for cigarettes in eleven countries and concluded that advertising bans had little effect on cigarette demand. Finally, Boddewyn presents data from 16 countries which suggest strongly that advertising bans have not had the effects expected by those advocating their introduction.