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During the winter season, enjoy Tremblant's 4 distinct ski slopes. You will never grow tired of the different difficulty levels, snow conditions and panoramas that offer endless mountain adventure possibilities and combinations.More Details
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text:
DEC AXP Review
The Alpha computer I played with for this review was loaned to SSC by DCG Computers, Inc. of Londenderry, NH. DCG can be reached via e-mail at firstname.lastname@example.com or by a visit to their web site at www.dcginc.com. DCG's goal is to produce affordable computers based on Digital's Alpha Technology. The loaned AXP was a model EV5-333Mhz with 64 MB of RAM, a 1 GB hard drive and a quad speed CD ROM. DCG markets it for about $7,100.
My first hands on experience with the AXP was trying to fix it—always a good way to start. The AXP EB164 had arrived, and had been mysteriously "broken" during a second boot attempt. Evidently, the first boot had worked fine, but someone in the office had changed a BIOS setting, rebooted and "Kaboom...Alpha bits." Now, although everything appeared normal, the system would not even display the BIOS information. The hardware was functional, and the cards, SIMMs and cables were properly seated.
The system I wanted to install was Craftworks Linux, and since no one would 'fess up to changing the BIOS setting, much less to what it had been changed, I called Craftwork's Tech Support. The Tech Support people were friendly and helpful, and even gave me the answer to the problem—always a plus—the BIOS of the AXP has hard coded operating-system-dependent boot logic, i.e., the AXP only knows how to boot DEC Unix and Windows NT. The "someone" had set the BIOS switch to DEC Unix from NT, a perfectly reasonable thing to do considering the options. Wrong! For a Linux installation, the switch must start out set to NT, then you create and format a super tiny MS-DOS FAT partition (as partition 1), make it bootable and install the AXP equivalent of [cw]loadlin[ecw] in it. This hack will you get you booted okay, but it would be nice to have a Linux option to begin with.
After the initial boot problems were fixed, so was the AXP, and we started the installation of Craftworks 2.1 version of Linux. Due to the special AXP BIOS feature and the fact that MS-DOS was involved in some way, the installation was something other than "smooth and refreshing". One unsuccessful installation was caused by veering from the suggested partition size values. The second installation went fine, as I used all the suggested sizes and followed all the steps as given.
After completing the installation, I was able to boot the AXP from its own drive and log in seconds later. It was incredibly fast—RISC fast—333Mhz fast—faster than a speeding bullet fast (well, almost)! Using the AXP was a lot of fun—no waiting on your prompt to come back, it was always there. The AXP was so fast (see below) and performed so well, it was like a dream, then our next stumbling block appeared. Following a kernel build of 4-5 minutes, I typed [cw]make clean.[ecw]. Shortly after make began execution, the script died with a segmentation fault. Following this failure, many of the regular, previously working utilities (e.g., ps, finger, telnet, inetd, init) began failing. The only fix I found was to reboot. Everything would run fine for hours, even through concurrent compiles of GhostScript and the kernel, but as soon as I would run the make clean script, everything would quit working. Through various experiments, I found that any embedded rm command would cause a segmentation fault, after which the system was totally unstable. I further found that this problem was a bug in the version of Linux that I was using. The problem went away with an upgrade of the kernel to a later version (1.3.89).
Our systems administrator, Liem Bahneman, ran a lot of benchmarks, including dhrystone 1.1, iozone (HDD performance), bonnie (HDD performance), and Byte UNIX benchmarks. Unfortunately, none yielded accurate results due to a known flaw with math in the C library (libm) as ported to Linux/AXP at that time. Another "benchmark" he ran was a render of a povray animation (i.e., ray tracing). To quote Liem, "From my estimates, the same 72-frame, 320X240 animation render that took 13 hours on a Sparc20 would have taken approximately 4 hours on the AXP as tested. This is an estimate, because the render could not complete due to math faults."
I then installed Red Hat's version 3.0.3 of Linux finding it quite similar to Craftworks. Again, installation required the use of MILO (similar in functionality to LILO) and a DOS FAT partition. Following the guidelines carefully, I had it up and running quickly with no problems. Well after all, I was now an expert, having done it once before. Red Hat for the AXP looks and feels like Red Hat for the x86 except, of course, it's much faster. Red Hat's version of Linux did not have the embedded rm bug described above.
With Linux becoming more robust every day, the AXP running Linux will be a solid network daemon/file server. Especially since math-intensive applications are no longer flawed by a libm bug (this bug has now been fixed), and all "speed-matters" applications are math-intensive. If you are shopping for the high-end performance offered by the AXP, this is the machine for you.
Bryan Phillippe (email@example.com) is a 21-year-old Linux enthusiast who also enjoys the company of his fiancee, rollerblading and street-style snowboarding.
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Best thing about being a firefighter: "You have the ability to affect positive change every day you work, and firefighters do it without any praise whatsoever." Although news reports emphasize fire property damage, "We look at it as, 'What did we save?'"
Worst thing about being a firefighter: "I never had any complaints. The schedule's great. It might be the fact of how much danger and how often the firefighter is in danger and the public is not aware of it."
Best thing about being chief: "I see the ability to enact some changes." Top priorities are getting back to the staffing level before state aid cuts and meeting national fire response standards.
Worst thing about being chief: He has to turn down comedy gigs. "That's the way I de-stress. I don't have time to do that [now]."


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text:
Primary pancreatic lymphoma--pancreatic tumours that are potentially curable without resection, a retrospective review of four cases.
ABSTRACT Primary pancreatic lymphomas (PPL) are rare tumours of the pancreas. Symptoms, imaging and tumour markers can mimic pancreatic adenocarcinoma, but they are much more amenable to treatment. Treatment for PPL remains controversial, particularly the role of surgical resection.
Four cases of primary pancreatic lymphoma were identified at Prince of Wales Hospital, Sydney, Australia. A literature review of cases of PPL reported between 1985 and 2005 was conducted, and outcomes were contrasted.
All four patients presented with upper abdominal symptoms associated with weight loss. One case was diagnosed without surgery. No patients underwent pancreatectomy. All patients were treated with chemotherapy and radiotherapy, and two of four patients received rituximab. One patient died at 32 months. Three patients are disease free at 15, 25 and 64 months, one after successful retreatment. Literature review identified a further 103 patients in 11 case series. Outcomes in our series and other series of chemotherapy and radiotherapy compared favourably to surgical series.
Biopsy of all pancreatic masses is essential, to exclude potentially curable conditions such as PPL, and can be performed without laparotomy. Combined multimodality treatment, utilising chemotherapy and radiotherapy, without surgical resection is advocated but a cooperative prospective study would lead to further improvement in treatment outcomes.
- Gastroenterology and Hepatology 12/2012; 8(12):850-2.
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Page 1
BioMed Central
Page 1 of 9
(page number not for citation purposes)
BMC Cancer
Open Access
Case report
Primary pancreatic lymphoma – pancreatic tumours that are
potentially curable without resection, a retrospective review of four
Peter S Grimison*1,2, Melvin T Chin1, Michelle L Harrison1 and
David Goldstein1,2
Address: 1Institute of Oncology, Prince of Wales Hospital, Sydney, Australia and 2Faculty of Medicine, University of New South Wales, Sydney,
Email: Peter S Grimison* - email@example.com; Melvin T Chin - email@example.com;
Michelle L Harrison - email@example.com; David Goldstein - firstname.lastname@example.com
* Corresponding author
Background: Primary pancreatic lymphomas (PPL) are rare tumours of the pancreas. Symptoms,
imaging and tumour markers can mimic pancreatic adenocarcinoma, but they are much more
amenable to treatment. Treatment for PPL remains controversial, particularly the role of surgical
Methods: Four cases of primary pancreatic lymphoma were identified at Prince of Wales Hospital,
Sydney, Australia. A literature review of cases of PPL reported between 1985 and 2005 was
conducted, and outcomes were contrasted.
Results: All four patients presented with upper abdominal symptoms associated with weight loss.
One case was diagnosed without surgery. No patients underwent pancreatectomy. All patients
were treated with chemotherapy and radiotherapy, and two of four patients received rituximab.
One patient died at 32 months. Three patients are disease free at 15, 25 and 64 months, one after
successful retreatment. Literature review identified a further 103 patients in 11 case series.
Outcomes in our series and other series of chemotherapy and radiotherapy compared favourably
to surgical series.
Conclusion: Biopsy of all pancreatic masses is essential, to exclude potentially curable conditions
such as PPL, and can be performed without laparotomy. Combined multimodality treatment,
utilising chemotherapy and radiotherapy, without surgical resection is advocated but a cooperative
prospective study would lead to further improvement in treatment outcomes.
Primary pancreatic lymphoma (PPL) is rare, comprising
less than 0.5% of pancreatic tumours[1]. To distinguish
PPL from secondary involvement of the pancreas by non-
Hodgkin's lymphoma, Behrns' clinical and diagnostic cri-
teria of PPL include: mass predominantly within the pan-
creas with grossly involved lymph nodes confined to the
peripancreatic region, no palpable superficial lymphaden-
Published: 04 May 2006
BMC Cancer 2006, 6:117doi:10.1186/1471-2407-6-117
Received: 03 January 2006
Accepted: 04 May 2006
This article is available from: http://www.biomedcentral.com/1471-2407/6/117
© 2006 Grimison et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Page 2
BMC Cancer 2006, 6:117http://www.biomedcentral.com/1471-2407/6/117
Page 2 of 9
(page number not for citation purposes)
opathy, no hepatic or splenic involvement, no mediasti-
nal nodal enlargement on chest radiograph, and normal
white cell count [2]. Presenting symptoms are non-spe-
cific, typically including abdominal pain, weight loss,
nausea and vomiting [2]; but also jaundice, acute pancre-
atitis, and small bowel obstruction [3]. PPL can be diffi-
cult to differentiate from pancreatic adenocarcinoma
without definitive pathological diagnosis[3], and correct
diagnosis is crucial given that PPL has differing manage-
ment and usually a much better prognosis. The sizeable
cohort of patients with PPL who are not cured with cur-
rent treatment demands further improvements. Optimal
treatment of PPL remains controversial, particularly the
role of surgery and radiotherapy.
A retrospective analysis of patients with PPL at our institu-
tion was conducted, to examine our treatment outcomes
with modern multimodality therapy. We present a case
series of four patients – one of the few in the recent litera-
ture when newer therapies such as rituximab have become
available – and contrast outcomes with previously pub-
lished case series.
An electronic search through the medical oncology
department records of Prince of Wales Hospital (Sydney,
Australia) identified four cases of PPL among 481 cases of
non-Hodgkin's lymphoma between 1990 and 2005. Med-
ical records were reviewed, in regards to age, sex, present-
ing symptoms, radiological appearance, histological
diagnosis and method, staging investigations, treatment
regimen and outcome.
Staging was assigned by a modification of the Ann Arbor
classification [4]; accordingly stage IE disease is confined
to the pancreas, and stage IIE disease involves the pan-
creas and peripancreatic nodes. Histological categorisa-
tion was according to the Revised European American
Table 1: Patient characteristics, treatment and outcomes
Case 1Case 2Case 3 Case 4
Presenting Symptoms
Abdominal pain, nausea,
weight loss then jaundice
5 weeks
Endoscopic ultrasound FNA
6 cm pancreatic mass with
biliary obstruction and
portal vein involvement
500 kU/L
Vomiting, weight loss
Dyspepsia, weight loss
Abdominal pain, weight loss
then jaundice
4 months
Pancreatic mass and
peripancreatic lymph nodes
Delay until diagnosis
Method of diagnosis
CT appearance
3 months
Large peri-pancreatic mass
18 months
5 cm pancreatic mass
Ca-19.9 level*
Pre-treatment LDH
50 kU/L
Not available
Grade II follicular non-
Hodgkins lymphoma
Low risk (FLIPI 1/5)
39 kU/L
Prognostic index
Low-intermediate risk (IPI 2/
R-CHOP * 4 then involved-
field RT
NED at 23 months
Low-intermediate risk (IPI 2/
CHOP * 3 then involved-
field RT
Local recurrence at 32
months post-diagnosis, with
poor tolerance of 2nd line
chemotherapy and rapid
treatment-related death
Low-intermediate risk (IPI 2/
3 * CHOP then involved-
field RT
Out of field recurrence at 21
months post diagnosis.
Salvage chemotherapy and
autologous SCT. NED at 64
months from diagnosis
TreatmentInvolved-field RT then CVP
then rituximab
NED at 25 months
CHOP – Cyclophosphamide, doxorubicin, vincristine, prednisone
CVP – Cyclophosphamide, vincristine, prednisone
DLBCL – diffuse large B-cell non-Hodgkin's lymphoma
FLIPI – Follicular lymphoma international prognostic index [8]
IPI – International Prognostic Index for the Aggressive Non-Hodgkin's Lymphomas [7]
NED – No evidence of disease
R-CHOP – Rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone
RT – Radiotherapy
SCT – Stem cell transplantation
* Normal Range 0–50 kU/L
** Histology defined according to REAL classification.[5]
*** Staging defined according to Ann Arbor staging system.[4]
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Page 3 of 9
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Lymphoma (REAL) classification [5]. Performance status
was defined according to the Eastern Cooperative Oncol-
ogy group (ECOG) scale [6]. The prognosis of patients
was assessed using the criteria of the International Prog-
nostic Index [7] for aggressive lymphomas, and the Follic-
ular Lymphoma International Prognostic Index (FLIPI)
[8] for follicular lymphomas respectively.
Previously reported cases of PPL published between 1985
and 2005 were identified through a Medline search of the
English literature using the keywords of "pancreas" and
"lymphoma". Further case series were identified through
citation review of identified articles. Single case reports,
and cases of stage III/IV disease were excluded.
Case series
Four cases were identified of this rare condition at our
institution. All cases were male, and age ranged from 56
to 70. Summary data is presented in table 1.
Case 1
A 64 year old man presented with a five week history of
right upper quadrant pain, nausea, and jaundice, with five
kilograms of weight loss. Liver function tests demon-
strated biliary obstruction. Serum Ca-19.9 tumour marker
assay was markedly increased at 500 kU/L (normal range
0–40). Abdominal CT demonstrated a 6 cm solid mass
within the head of the pancreas, invading the portal vein,
associated with biliary obstruction, but without lymphad-
enopathy or hepatic involvement (Figure 1). At ERCP a
long lower common bile duct stricture was stented with
prompt relief of biliary obstruction. Although pancreatic
adenocarcinoma was strongly suspected, endoscopic
ultrasound-guided biopsy revealed CD20 positive diffuse
large B cell non-Hodgkin's lymphoma. Staging PET scan
and bone marrow aspirate and trephine (BMAT) noted
uptake in the coeliac nodes, without evidence of wide-
spread dissemination of lymphoma.
Pre-operative assessment avoided the need for exploratory
laparotomy. 4 cycles of CHOP (Cyclophosphamide, Dox-
orubicin, Vincritine, Prednisone) with concurrent rituxi-
mab (anti-CD20 chimeric
Genentech, CA, USA) was administered with complete
response. Chemotherapy was then ceased because of
asymptomatic anthracycline-induced decline in ejection
fraction. Involved field external beam radiotherapy (36
Gray in 20 fractions) was administered. Fifteen months
following diagnosis the patient remains in complete
monoclonal antibody,
Case 2
A 70 year old man described a several month history of inter-
mittent vomiting, anorexia and weight loss, on a back-
ground of chronic renal failure due to polycystic kidney
disease (serum creatinine 450 umol/L; normal range 60–
110 umol/L). MRI (magnetic resonance imaging) of the
abdomen (Figure 2) demonstrated a large confluent mass
lying above the head of the pancreas, posterior to the stom-
Case 2 MRI
Figure 2
Case 2 MRI. MRI (magnetic resonance imaging) shows mass
arising from head of pancreas, as well as hepatic and renal
Case 1 CT Scan
Figure 1
Case 1 CT Scan. CT scan of upper abdomen in arterial
phase shows low density soft tissue in region of pancreatic
head and posterior to body of pancreas, and biliary stent
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Page 4 of 9
(page number not for citation purposes)
ach, as well as prominent renal and hepatic cysts, without
lymphadenopathy or mesenteric vessel involvement. Ca-
19.9 was mildly elevated. CT-guided FNA was non-diagnos-
tic, and endoscopic ultrasound was not available. At surgery
– a risky procedure given his renal impairment – a large
tumour was noted posterior to the duodenum, with bulky
lymphadenopathy and peritoneal seeding. Although pancre-
atic carcinoma or polycystic kidney disease of the pancreas
was suspected, intra-operative frozen section revealed CD20
positive diffuse large B-cell lymphoma (Figure 3 and 4). For-
mal staging with gallium scan and BMAT did not reveal fur-
ther dissemination. Given potential for cure with
chemotherapy and radiotherapy, resection was not per-
Systemic combination chemotherapy with dose-modified
CHOP was administered, after explanation of risk of sig-
nificant toxicity and treatment-related end-stage renal fail-
ure. Dose-limiting toxicity included neutropaenia,
cardiotoxicity and sensory neuropathy, which required
cessation of treatment after only three of a planned six
cycles. Progress CT scan demonstrated over 50% reduc-
tion in size of the pancreatic mass. Involved field radio-
therapy (45 Gray in 25 fractions) was well tolerated,
inducing radiological complete remission.
Thirty months after diagnosis end-stage renal failure
occurred, requiring hemodialysis. Thirty-two months fol-
lowing diagnosis (23 months following therapy) the
patient suffered symptomatic mediastinal and gastric
recurrence. Second-line combination chemotherapy
(DHAC – carboplatin, doxorubicin, cytosine arabinoside,
dexamethasone) was poorly tolerated, with febrile neu-
tropaenia and grade three gastrointestinal bleeding. The
patient had a limited response, and died a short time later.
Case 3
A 56 year old man presented with progressive dyspepsia
and 12 kg of weight loss over 18 months. Ultrasound and
CT revealed a five cm pancreatic mass involving the trans-
verse colon; without lymphadenopathy, mesenteric vessel
or hepatic involvement. At laparotomy for a planned
Whipple's procedure, histopathology from open biopsy
of the pancreatic mass and adjacent nodes was consistent
with CD20-positive grade II (mixed small and large cell)
follicular lymphoma. PET scan and bone marrow staging
revealed regional nodal involvement. Resection was not
Treatment consisted of involved field radiotherapy (36 Gy
in 20 fractions), with sequential CVP chemotherapy for
five cycles and sequential rituximab for four cycles.
Restaging confirmed complete response, and the patient
remains in complete remission 25 months following diag-
Case 4
A 61 year old man experienced progressive epigastric and
back pain, 12 kg weight loss and then jaundice. Liver func-
tion tests were consistent with biliary obstruction. Ca19.9
was within normal range. CT scan revealed a pancreatic
mass and peripancreatic lymphadenaopthy, without
mesenteric vessel or hepatic involvement. ERCP and inser-
tion of biliary stent relieved obstruction, however biliary
brushings and subsequent FNA were non-diagnostic.
Laparotomy and open biopsy of the peripancreatic lymph
Case 2 Biopsy CD20 stain
Figure 4
Case 2 Biopsy CD20 stain. CD20 positive staining of cells,
consistent with B cell origin (×200)
Case 2 Biopsy
Figure 3
Case 2 Biopsy. Histological section shows large mononu-
clear cells, consistent with diffuse large B-cell lymphoma
(H&E stain, ×200)
Page 5
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Page 5 of 9
(page number not for citation purposes)
nodes revealed CD20 positive diffuse large B-cell lym-
phoma, and resection was not performed.
Treatment consisted of three cycles of CHOP chemother-
apy followed by involved field radiotherapy (42 Gy in 19
fractions). The patient had a complete response to treat-
ment, however relapsed out of field 21 months following
diagnosis (17 months after treatment), with complete
response to second-line ICE chemotherapy, high-dose
BEAM chemotherapy and autologous stem cell transplan-
tation. After 64 months following diagnosis (37 months
from 2nd treatment), the patient remains in remission.
Literature review
Literature review identified 103 additional cases of PPL
from 11 case series. Histopathology; use of successful
non-operative biopsy; use of resection, chemotherapy and
radiation; and outcomes are described in table 2.
High-grade B cell lymphomas were most commonly iden-
tified (45% of cases), followed by low grade B lymphomas
(15%) and other B cell lymphomas (34%). T cell lympho-
mas, although very uncommon (4% of cases), carried a
dismal prognosis. Our series was comparable to other
series with 75% high-grade B cell lymphomas and 5% low
grade lymphomas. Histological diagnosis was established
by non-operative biopsy in 29 of 105 cases (28%),
laparotomy in 69 of 105 cases (65%), and autopsy in 7 of
105 cases (7%). Surgical resection of the tumour was per-
formed in 23 of 107 cases (21%). Chemotherapy was
administered in 80 of 107 cases (75%). Radiotherapy was
administered in 33 of 105 cases (31%).
Comparisons were made between treatment groups.
Without any definitive treatment, results were uniformly
poor with no patients free of disease and poor long-tem
survival. Patients treated with chemotherapy and/or radi-
otherapy – without resection – did not appear to have
worse outcomes than resected patients. Formal statistical
comparison was not able to be performed.
In our series of non-surgical multimodality therapy, three
of four patients were free of disease at time of follow up,
with mean survival 34 months, and 2-year survival of
Our case series illustrates that the clinical presentation of
PPL can be difficult to differentiate from pancreatic aden-
ocarcinoma without definitive pathological diagnosis.
Reliance on symptoms, imaging and tumour markers – in
the absence of definitive pathological diagnosis of sus-
pected pancreatic adenocarcinoma – can potentially result
in the misdiagnosis of a small minority of potentially cur-
able patients. This is important as the prognosis and man-
of PPL differs greatly from that of
Appearances on CT can be helpful to differentiate the two
conditions, but are not definitive[9,10]. Ca19-9 is the
most useful tumour marker in pancreatic carcinoma, but
can be misleading as it may also be elevated in other
malignancies, particularly of the upper gastrointestinal
tract, including PPL as described in case one [11]. Without
definitive pathologic diagnosis, potentially curable condi-
tions such as PPL; as well as other malignancies with more
favourable prognosis, including periampullary, distal
common bile duct, duodenal and mucinous cyst adeno-
carcinomas, may be misdiagnosed[12].
Non-operative evaluation and biopsy of pancreatic
masses can avoid the need for invasive surgery, if condi-
tions such as PPL are found. The majority of cases of PPL
in our literature review required laparotomy for diagnosis,
which may have been avoided with successful non-opera-
tive biopsy and modern combined modality treatment.
Radiological-guided percutaneous FNA of the pancreas is
a very useful technique, which requires experienced radi-
ologists and cytopathologists to obtain a diagnosis on a
small amount of tissue[3]. Endoscopic ultrasound has
greatly improved the accuracy of diagnosis and obtaining
diagnostic tissue [13-18]. Diagnosis of PPL may be
extremely difficult on haematoxylin-eosin stains alone,
and resemble poorly differentiated carcinoma and reticu-
lum cell sarcoma[19], thus immuno-histochemical stains
and flow cytometry are essential[3]. It must be empha-
sised that cytological diagnosis may not be adequate for
diagnosis and categorisation of an abdominal mass, and
tissue biopsy should be considered. In some situations
(including two of our patients with non-diagnostic FNA),
laparotomy may be required for definitive diagnosis.
Treatment of PPL remains controversial – particularly the
role of surgery and radiotherapy – and based on our findings
we do not support routine pancreatectomy. All patients in
our case series received multimodality treatment with both
chemotherapy and radiotherapy, without surgical resection.
Experience from our case series and literature review (table
2) indicates that this modern treatment regime achieves
favourable outcomes, comparable or better than surgical
series, without the morbidity of surgical resection. Most
modern authors would not recommend surgery except when
non-surgical diagnosis is unsuccessful [20-22]. Surgery is
difficult in PPL because tumours are large, and often associ-
ated with an otherwise histologically normal pancreas, car-
rying a high risk of postoperative pancreatic fistula[23].
Technical improvements in pancreatic surgery have led to
reduced peri-operative morbidity and mortality, and in con-
trast Koniaris argues that pancreatectomy should be reevalu-
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ated as a method of improving local control and cure
Table 2: Literature review – patient characteristics, treatment and outcomes – abbreviations and reference list
Yearn Pathology
of cases)
rapy or RT
Outcomes with
resection or RT
Outcomes with
and RT without
Hart USA
198714 Histiocytcic
Poorly diff
Well diff
T cell (1)
ated (1)
mixed (2)
cleaved (1)
0 of 141 of 14 CHOP (14) 1 of 140 1 NR
6 alive at mean 32 months (18–48
2 died within 3 months
5 died at mean 35 months (6–108)
(5 of 13 received RT)
1 of 2 MACOP-B (1)0 of 20 1 alive at 95
chemo, RT
1 alive at 21
198912 0 of 12 1 of 12CHOP (9) 5 of 12 2 died in
period after
4 died –
survival 5
2 relapsed
or died
4 alive at 3,36,48,84 months
5 died at 2–11 months
(5 of 9 received RT)
19937 NR 0 of 70 of 7 CHOP (1)
0 of 7
3 alive at 60,72,96
cleaved (2)
Mixed (3)
4 of 12 1 of 12CHOP (4)4 of 121 NR
chemo, RT
2 died – mean
survival 13 months
3 died – mean
survival 26 months
(5 died after RT
only – mean
survival 22 months)
2 alive at 30,84
19965DLBCL (5)2 of 51 of 5CHOP (4)
CHOP- Bleo
2 of 501 alive at 23
3 alive at
(All received
OPEN or
3 alive at
(2 received
CHOP and
4 died at
4 alive at
(6 received
chemo, 4 no
chemo, 0 RT)
2 alive at 24,24
follicular (1)
6 of 11 3 of 11See legend*7 of 110
1 alive at 191
4 alive at
3 died at 12,16,80
follicular (1)
3 of 8 3 of 8CHOP (6)
5 of 80
1 alive at 24
2 alive at 51,128
2 died at 9,37
a Japan
oma (2)
B follicular
T peripheral
T anaplastic
large (1)
High grade
B cell (1)
Low grade B
macytic (2)
2 of 1910 of 19CHOP (5)
Mitomycin (1)
Tegafur (1)
chemo (1)
0 of 197 died at
72 months
2 died at 2,8
8 of 80 of 8Chemo (4)
Chemo and
auto SCT (2)
3 of 8
03 alive at 5,6,76
3 alive at 2,7,72
200553 of 52 of 5CVP/CHO
2 of 501 alive at 160
1 died at 8
CHOP or
1 alive at 60 months
2 died at 67, 88 months
(2 of 3 received RT)
Follicular (1)
1 of 4 0 of 4CHOP (2)
4 of 400 1 died 32 months
3 alive 15,25,64
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It is pertinent to consider the diminishing role of surgery
in other localised extra-nodal lymphoma. Historically, the
treatment of localised gastric non-Hodgkin's lymphoma,
excluding MALT (mucosa-associated lymphoid tissue)-
type lymphomas, was based on surgery – to ensure ade-
quate diagnosis and staging, and maximise survival rates
[24]. Three recent large prospective studies [24-26] and
two smaller randomised controlled trials [27,28] of chem-
otherapy vs. combined surgery and chemotherapy have
reported equivalent survival. Thus the role of surgery in
gastric lymphoma may be limited to rare patients with
acute complications or residual disease following non-
surgical treatment [26,29] In intestinal non-Hodgkin's
lymphoma, following a prospective study there is a trend
away from extensive resection [30]. Localised extraintens-
tinal non-Hodgkins lymphoma has been treated without
surgery for over two decades, following numerous well
conducted prospective clinical trials. These changes in
management illustrate the need for large cooperative pro-
spective studies in PPL, which will better define any bene-
fit of resection, as well as the role of therapies such as
radiotherapy and rituximab.
Radiotherapy has had only limited reported use in the
treatment of PPL (see table 2). Potential concerns about
the safety of radiotherapy in this region may be unneces-
sary, as toxicity has been substantially reduced with three-
dimensional treatment planning and conformal delivery
of radiotherapy[31]. With these modern techniques small
bowel toxicity is minimised, and none of our patients
required radiotherapy interruption. The role of radiother-
apy in early stage high-grade lymphoma remains contro-
versial in a global sense. In localised intermediate and
high-grade non-Hodgkin's lymphoma, chemotherapy
using the CHOP regimen plus adjuvant radiotherapy is
superior to chemotherapy alone[32]. Intensive chemo-
therapy regimens without radiotherapy have been shown
to be superior to CHOP plus involved field radiother-
apy[33]. An important question asks whether the addition
of adjuvant radiotherapy to more intensive chemotherapy
regimens would further improve outcomes[34]. We advo-
cate combined multimodality therapy with both chemo-
therapy and radiotherapy for PPL.
Two of our four patients received rituximab (anti-CD20
chimeric monoclonal antibody, Genentech, CA, USA).
We are not aware of its use in other series of PPL, however
its use has been reported in gastric lymphoma [35], and
evidence exists of its benefit combined with chemother-
apy in other high-grade lymphoma for patients aged over
Biliary sepsis is a potential problem of multimodality
therapy in the setting of PPL, due to both the frequent
presence of biliary stents, and the risk of neutropaenia. A
study of endobiliary stents in multimodality therapy of
pancreatic carcinoma reported low rates of complications,
with 15 of 101 cases complicated by occlusion or migra-
tion, and no uncontrolled biliary sepsis or stent-related
death[37]. Another study of patients with malignant bil-
iary obstruction and bile duct stents did not find increased
biliary complications in patients receiving chemother-
apy[38]. Metal stents are superior to plastic stents for
long-term patency [39-41]. Prompt recognition and treat-
ment of biliary complications is important to allow ongo-
Excluding 2
29 of 105
23 of 107 80 of 107 Excluding
33 of 105
Excluding 2
0% (0 of 15)
Mean 13
of 15)
Excluding 5
72% (13 of
Mean 34
of 18)
57% (36 of 63)
Mean 38 months
2YS of 62% (28 of
45) – excludes 18
*CHOP (1), CHOP-Bleomycin (2), CHOP-OPEN (2), CHOP-Bleomycin, CMED, ESHAP (1), CHOP-Bleomycin, OPEN (1), CHOP, OAP-Bleomycin, MIME (1), CHOP-
Bleomycin, MINE, ESHAP, Autologous SCT (1), IM-Etop, HOP (1), ESHAP, BACOS, MIME (1)
**excludes 7 patients with stage III/IV NHL
BACOS – bleomycin, doxorubicin, cyclophosphamide, vincristine, methylprednisolone
CAMEL – cyclophophamide, adriamycin, vincristine, prednisone Chemo – chemotherapy
CHOP – cyclophosphamide, doxorubicin, vincristine, prednisone
CMED – cyclophosphamide, methotrexate, etoposide, dexamethasone
CVP – cyclophosphamide, vincristine, prednisone
DLBCL – diffuse large Bcell lymphoma
ESHAP – etoposide, methyprednisolone, high-dose cytarabine, cisplatin
HOP – doxorubicin, vincristine, prednisone
IM-etop – ifosfamide, methotrexate, etoposide
MIME – MESNA, ifosfamide, methotrexate, etoposide
MINE – MESNA, ifosfamide, mitoxantrone, etoposide
NED – no evidence of disease
NR – not reported
OAP-Bleomycin – vincristine, cytarabine, prednisone, bleomycin
OPEN – vincristine, prednisone, etoposide, mitoxantrone
RT – radiotherapy
SCT – stem cell transplantation
References for table 2 – Hart[12], Webb[22], Mansour.[45], Tuchek[47], Behrns.[2], Ezzat[48], Bouvet.[21], Koniaris[23], Nishimura[49], Nayer.[3], Arcari[20]
Table 2: Literature review – patient characteristics, treatment and outcomes – abbreviations and reference list (Continued)
Page 8
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Page 8 of 9
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ing therapy, as happened on several occasions to our
We have examined for any possible association between
polycystic kidney disease and PPL, given the existence of
both conditions in case two. Although polycystic kidney
disease has been associated with pancreatic cystadenoma
and cystadenocarcinoma in a small number of case
reports [42-44], we are not aware of any association with
pancreatic lymphoma.
The study of PPL is limited by the rarity of the condition,
and the consequent lack of randomised trials or large case
series. The comparison of our case series with other series
must be interpreted cautiously, given variable follow-up
(range two – 108 months), incomplete data in some case
series[2,3,12,45], and the inherent publication bias
within case series favouring positive results, as described
by Albrecht[46]. We strongly advocate a multi-centre pro-
spective study of patients with PPL to improve patient out-
PPL is a rare but potentially curable pancreatic tumour,
and mandates pathological diagnosis of all pancreatic
masses, as its treatment and prognosis differs from aden-
ocarcinoma. Non-operative diagnosis may avoid the need
for surgery, as outcomes with chemotherapy and radio-
therapy – without surgical resection – compare favourably
to surgical series. Nevertheless a sizeable cohort of
patients are not cured with modern therapy, and we advo-
cate a prospective study to further improve treatment out-
Competing interests
The author(s) declare that they have no competing inter-
Authors' contributions
PSG collected the data for the case series and the literature
review, and drafted the manuscript. MC also collected
data for the case series. MH also drafted the manuscript.
DG conceived the study, participated in its design and
coordination, and helped to draft the manuscript. All
authors read and approved the final manuscript.
Written consent was obtained from the patients or their relatives for pub-
lication of the study.
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NEW YORK (AP) — Publishers and the public met this weekend at BookExpo America, the annual industry convention, and seemed to speak in different languages.
Publishers, public meet at BookExpo
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I am purchasing a power window motor for the front drivers door and having replaced by an independent shop. The parts store tells me there are 2 motors available. One with 8 gears and the other with 6 gears. Which do I need. If the window rolls down (very slowly) you have to beat on the lower part of the door and it will zip right up.
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Answer #1Visitor, August 02, 2011, 18:43
i have a 2004 canyon and have replaced the drivers door window motor twice in 5 years it has 8 tooth gear
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Federal Chief Information Officer Vivek Kundra pushed for the development of geographic information systems such as the snow response system when he was the city's chief technology officer, he told Federal Computer Week in past interviews.
In 2008, while he was still Washington's CTO, the snow response system was one of 10 GIS projects Kundra identified for enhancements, according his testimony at a public oversight hearing about the city's capital improvements budget.
The city uses GIS maps and databases to support several functions including emergency management and response, economic development and planning, crime analysis and law enforcement, transportation and public works management and disaster recovery according to the city's Web site.
The Snow Response Reporting System won a significant achievement award from the Public Technology Institute for its 2007-2008 Technology Solutions Awards, according to the institute's Web site.
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Marble Parrot Bookends, Italy 1921
Hey, so my grandparents moved out of their house into an apartment, and we have since cleaned it out. in one of their back storage rooms we found crates full of their wedding gifts from 1954. in one of them was these bookends. they are on white marble stands, their wings are tucked in and purple. Their body is more of a yellowish color and their heads are a pink. If anyone could please tell me who carved these and how much their estimated worth is please let me know.
hey, well that seems to hard so I just put a link to facebook up here.
here it is:
Here is a link that might be useful: facebook picture
Dyed alabaster, value unknown.
See these for a lot of their cousins, although yours are less ornately carved than some.


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From Investor Glossary:"A blow-off top refers to an extremely fast spike up in a stock's price, followed by an extremely fast and severe drop in price."Why do I want to wait until "an extremely fast and severe drop in price" to short. Seems like shorting in the middle of a blow off top is the best.I'm not saying Cat is a horrible company. They are doing great as a company. The stock price, however, has gotten way ahead of Cat the company. If the earnings do double in 2 years, that does justify today's price of $92. But that's 2 years from now.There is no way the current price can be sustained. Especially with union contract negotiations under way. Now that Cat is doing quite well as a company, the union will have better bargaining in asking for more.I'll short from here down to mid 70's by end of January and middle of Feb. Then I'll buy long and hold for the slow ride up to 100-120 by the end of 2012.I'm no day trader.
The blowoff top has not occurred yet. The blowoff will likely not occur until the stock price is well north of 100. So while a short now may eventually see a profit, you will be nursing that short position for likely a few months. Simple rule: YOU DON"T SHORT OUT-PERFORMERS....But if you want to gamble....it's your shirt to lose!
I'd be nervous shorting a stock that is in an uptrend.But if I were a long term investor, I would absolutely wait for a pull back before buying in.
It's not as simple as saying "a stock is in an uptrend".Eventually that uptrend ends. And you can use valution metrics to help determine how close we are to that end.Start with a basic valution metric of p/e. And for a company like Cat, a p/e below 10 is a screaming buy. A p/e above 20 is a sell (or consider selling).Of course, you have to take earnings forecast into account to get future p/e. Well, earnings are predicted to double (and I believe they will) by end of 2012. So the future p/e of Cat, with a current price of $92 comes to about 15. That smacks right in the middle of the fair valuation range.But that is nearly 2 years from now.To me, that says the uptrend is nearing an end, and that possible "blow off top" could be right near that top.I certainly wouldn't want to wait until that blow off top became defined, because by then it is too late to short.


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Vanessa321 18-21, F 15 Answers 3 Jun 25, 2012
The overall IQ of human has improved immensely over time. so no
Best Answer
Is this rhetorical? Cause you have asked this question on EP.<br />
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Yes and I blame shows like family guy. I swear my IQ points drop every time I watch that show....and yet you can't seem to look away.
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may i endugle in your attention for one moment (btw i am very smart for a 11 year old my IQ is 210) SO LOL i can act dumb THo lol
Best Answer
Best Answer
Idiocrasy...for sure, and it's a good movie
Best Answer
the human race certainly is dumb now. but idk how dumb it was before. maybe me n you r just too smart for the rest of the world.
Best Answer
Best Answer
Related Questions
iguanachips 41-45, F 8 Answers 3 Oct 30, 2011
Human - 62,182 years existence. 2 arm, 2 leg, small skull. Capabilities estimated - unsubstantial. Numbers rising 18 million per 1.67 years. Formed from intense bacterial evolution...destresosves 66-70, M 12 Answers 2 Jul 22, 2012
lovelightlove 26-30, F 8 Answers 2 Mar 1, 2013 in WTK
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taketheworlddown 22-25, M 27 Answers 6 Jul 31, 2012
What do you think about this saying. There is only the human race. Nobody is Black, White, Brown, Yellow, or Red. Hmmmm.


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THS: Lexington Stakes
Tom and Jason handicap the Coolmore Lexington Stakes at Keeneland this week. watch video
Tom and Jason handicap the Coolmore Lexington Stakes at Keeneland this week. watch video
Bob Baffert trainee Castaway is the most likely of the 11 horses entered in the April 21 Coolmore Lexington (gr. III) that, should he win, could find himself in the starting gate on May 5 at Churchill Downs.
The $200,000 Coolmore Lexington Stakes (gr. III) at Keeneland April 21 could have implications on starting berths in the Kentucky Derby Presented by Yum! Brands (gr. I) at Churchill Downs May 5.
Jason and Tom handicap the Florida Derby and Louisiana Derby. watch video
Before any Triple Crown talk can start, Union Rags must handle his business against eight contenders in the $1 million Florida Derby (gr. I) March 31 at Gulfstream Park.
Do Daddy Nose Best and Went the Day Well both enter Steve's Derby Dozen for this week? Read to find out! watch video
Fountain of Youth (gr. II) winner Union Rags breezed a half-mile in company March 24 at Palm Meadows Training Center in preparation for a start in the $1 million Florida Derby (gr. I).
Risen Star Stakes (gr. II) winner El Padrino breezed five furlongs in 1:01 1/5 March 18 at Palm Meadows for trainer Todd Pletcher as he approaches a start in the upcoming $1 million Florida Derby (gr. I) at Gulfstream Park.
News Pending burst on the scene with his surprising second-place finish in the Fountain of Youth Stakes at odds of 27-1. But who exactly is this horse? read blog
As witnessed time and time again, the trainer pops with 3YOs when least expected read blog
Union Rags and El Padrino take over the top spots. watch video
With Algorithms scratched from the $400,000 Fasig-Tipton Fountain of Youth Stakes (gr. II), Union Rags made easy work of what had been a highly anticipated match-up at Gulfstream Park Feb. 26.
The high-anticipated 3-year-old race pits the current Derby favorite, Union Rags, against two undefeated and top-class horses from the barn of leading trainer Todd Pletcher, Algorithms and Discreet Dancer.
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|Klaravich Stables, Inc. and Lawrence, William H.
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|News Pending View Five-Cross Pedigree
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Hip 1717
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|Mill Ridge Sales, agent
Hip 1069
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Hip 236
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Hip 206
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|McKathan Brothers, agent
Prices in parentheses indicate a horse did not sell because it did not meet its reserve price.
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VietNamNet Bridge – The cool cold and fragile rains have created a land filled with the colors of flowers all the year round.
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Local film to debut at Berlin International Film Festival The much-talked about film – Big Father, Small Father and Other Stories – directed by Phan Dang Di will make its international debut at the 65th Berlin International Film Festival. This is the first ever Vietnamese film to screen at the festival, which... [Read more]
Ho Chi Minh City's climate condition is very advantageous for the development of tropical ornamental plants whose growing area has quickly increased recently. However there is no trading center for these products causing difficulties for suburban production units in supplying their products to consumers. A farmer in his orchid garden... [Read more]
The 27th National Art Photo Contest's opening ceremony. Photo: VNA Selected entries to the 27th National Art Photo Contest are being exhibited at the Centre for Fine Art and Exhibition in the northern port city of Hai Phong after being on display in resort Da Lat city, the Central Highlands... [Read more]
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Rose R Ellis Model
mPm StudiosPhotographer Male Kansas City, Missouri, US My MM URL: http://www.modelmayhem.com/mdcoram
Mayhem # 1146156
About Me
I love working with passionate people who want to create gorgeous images. I enjoy shooting beauty, fashion, and glamour and enjoy capturing high class alluring images without the use of nudity. My advertising and fashion photography has been published in numerous magazines and newspapers in the U.S. and Europe and even a few in Africa. 95% of my work includes studio strobes whether I'm working in a studio, your home, or on location. My lights are sometimes used to fill in shadows but mostly to create them.
I'm a bit of a techie nerd, love my wife and kids, love sports, love nature, love travel (especially Europe). Photography is my artistic passion.
My favorite type of photo shoot is a Domestic Shoot. Shooting where the model lives makes for a easy going experience and one where we can focus on being creative while using the surroundings you're already comfortable in. Everything from capturing you doing your makeup, fixing your hair, drinking a cup of coffee, reading a book on the couch, etc, etc, etc. Domestic shoots are a blast! The size and condition of your residence is of no concern at all - it simply does not make a difference. If you really don't want to pick up your messy place, we'll take advantage of the many awesome locations around town instead.
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Now Our Guests Can Shower
Progress has been made in the guest bathroom, folks. Which is good news since we're less than 30 hours away from the arrival of Sherry's mom and stepdad. Our first score was finding a shower curtain. Despite being burned by pattern in our last shower curtain attempt, we bought this guy at Target on Friday for about $20.
It definitely still looks kinda rough in there (still have to paint the walls and hang art, but we don't think we'll get to that before the inlaws arrive, uh, tomorrow). But getting back to the shower curtain, we think the pattern works much better because it's bigger when it comes to the scale. The large medallions don't compete with the tiny square tile on the walls and floor like the smaller scale yellow pattern in the last one we grabbed. The dark brown also introduced some nice contrast since the yellow tiles and off-white walls were sort of washing out the rest of the space. And because our old guest room bedding – which we plan to reuse – includes brown & white, while the walls in there are blue, this curtains sort of ties things together.
Then once we had the curtain finalized (and picked up a cheap white fabric liner to keep this guy from getting drenched, also from Target), we turned our attention to the bathmat – or the lack thereof. We originally brought home a brown one that matched the curtain but it was waaaay too dark. And walking into a bathroom to see a big brown spot on the floor wasn't the most, um, clean looking choice.
So we went back to Target and picked up three other options for a little bath mat fashion show (Sherry may or may not have clapped and chanted "fashion show, fashion show" as we made our purchase). First we tried this square one that almost blended right into the floor completely.
No dice. It just looked kinda dirty and blah.
Our next choice was the polar opposite. We decided to try a more colorful rectangular mat to pick up those blue tones in the curtain (and the adjoining deep teal guest bedroom).
We didn't really mind this one. It matched the curtain nicely and certainly would help us achieve our goal of bringing more color into the house.
But when we saw the third option we knew it was "the one." It just felt crisp and tailored without being matchy-matchy. The stripes are a fun counterpart to the circles in the curtain (the white and brown tones in each one keeps them related in a fun mixed & matched way).
What can we say? I guess even though we're embracing more color, we're still suckers for crisp white stuff from time to time. Especially with there's a white toilet, sink, and mirror in there (so it automatically ties right in). I guess when it comes to bathrooms, nothing trumps clean white linens for us (99.9% of hotels that we've stayed at always have plush white towels and bathrobes, so we want our guests to feel like Casa Petersik is just as spa-like and inviting). Long story short, we had a bath mat fashion show winner. So we hoisted it up and sang For He's A Jolly Good Fellow, removed the tag, and returned the others.
We also accomplished a few hardware updates yesterday. The most needed of which was a new toilet seat, since the old one boasted several chips in the lid and tears in the soft seat (and we're not really fans of the soft toilet seat thing anyways). Here's the least offensive shot of the old toilet seat that shows off some of those chips on the lid. We refrained from sharing the open lidded shots since we know some of you eat breakfast slash drink coffee while reading. You're welcome.
Replacing a toilet seat isn't rocket science, nor is it a very glamorous job. But I did my best to enjoy the process, and even flashed a thumbs up at the wife as she snapped this pic.
The whole switcheroo brought back memories of when I used a toilet seat for a 9th grade science project where I had to illustrate the anatomy of a mollusk (i.e. clams). In case you were wondering, toilet seats take well to dry erase markers. Yes, I really am that dorky. Go Team Mollusk.
We also replaced the old rusted shower head. It functioned just fine (the water pressure was great and there were thankfully no leaks to deal with) but it just didn't look very nice.
So we sprung for the cheapest multi-setting shower head at Target (it was $14) in an effort to fancy things up a smidge.
And after using some serious elbow grease to get the old one off, the new one went on within 60 seconds. So shiny, right? I can even see myself in it.
Speaking of being in it, I actually took the shower for a test run shortly after this installation. I figured if anything weird or gross was going to happen in the first use of this shower, I wanted it to happen to me and not my mother-in-law. Fortunately things were all good. In fact, the water pressure is better in there than our master bedroom. Lucky guests.
Last but not least was a quick zero-cost change. After removing the mirror on inside of the bathroom door (awkward!), we realize we were missing towel hooks… 'til we discovered them on the other side of the door while painting this weekend. Seriously, in the two months that we've lived here we never once closed the door to the guest bathroom to discover those towel hooks hiding back there until a few days ago. So I just unscrewed them from the back and reattached them to the inside of the door where they'll actually be seen and used (and Sherry spackled and painted the leftover holes on the lesser seen back side of the door).
We've still got a few other things (like towels, and maybe some art) to make the room look more complete and guest-ready, but at least it's completely functional now. Stay tuned for pics of the whole room after Sherry gets her kicks by adding a few accessories. And we still have to share our progress in the guest room. Which we're most likely working away on as you read this post.
In the meantime, have you guys made any recent bathroom upgrades? Or do you have any tips to share about how you get a guest bathroom ready for guests (besides buying some shampoo, conditioner and toothpaste – which is already on our to-do list along with fluffy towels and a few washcloths)? This is our first time having to furnish a devoted guest bathroom that we don't regularly use ourselves, so we're definitely feeling kind of JV about the whole thing.
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338 Comments
Love it! Any idea what color you're going to paint above the tiles? I think your other duvet cover (the one that was in your master bedroom) would look equally awesome in this bedroom.
For the guest bathroom, I always leave a few pretty glass cups on the vanity for my MIL (for her toothbrush, hairbrush, make-up, etc). It's more convenient than storing things in a damp travel bag.
I also write a little welcome message on the bathroom mirror with glass markers (though any water-based marker would work). It easily wipes off with a damp napkin or sponge. Sometimes, I just put a small message in the corner (e.g., "We're so happy you're here!"), but for special occasions I get more elaborate (when my sis stayed with me before she took the MCAT, I decorated the mirror with stethoscopes and band-aids).
Last tip: when I visited a friend, she left out a pair of guest slippers for me, which was so nice! It felt very spa-like and kept my feet cozy on her hardwood floors.
Have fun!!
I like the idea of warming up (even though its already pretty cheery with all that yellow!) your little bath with a tan/mocha tone to complement the tan in the floor tiles—mmmmm, mocha…..
I keep a little basket with an assortment of the many travel sized toiletries that are collected from hotels.
I also keep extra loofas, which I always prefer over a washcloth when I travel.
i love the shower curtain individually but i dont know if i like it against all that yellow. it seems busy to me. to each his own.
I agree. It makes the bathroom seem less retro and fun and more 70s.
I was thinking the same.. I like the curtain itself, but from the pictures it makes the shower itself look really dark. I prefer white or light curtains in dark rooms so more light gets in. But I don't know what your lighting is like in there either.. I'm sure either way it gets the job done.
I agree. Love the shower curtain. Love the mat. Love the yellow tiles. I just don't think I could put them all together. But, as it was mentioned – to each his own.
Hi guys! My sweet Caroline is just a month older than your little Clara. How in the world do you get so much done during the day? Aside from the fact that I am by myself at home, I'm lucky if Caroline takes 2 naps. Super lucky. You're my heroes!
Love the shower curtain! I really like to have a place for towels right in the bathroom – kind of hotel like. Might be hard to find the perfect spot, but it's so worth it. Everyone comments on how much they like our towel bar over the toilet in our guest bath. Convenient for hanging wet towels or stacking dry towels on top.
Here are some pics – http://houseography.blogspot.com/2010/09/suite-dreams-decorating-guest-bath.html
I really like the curtain. Target is the best for shower curtains in my opinion.
I would also recommend a candle and matches (or a discreet spray) and extra tooth brushes and some basic medicine like Advil and Tums.
Hi Youngsters….i am loving the process of watching you two transform your new pad! Just curious if you are still aiming for your 10 posts a week?
I don't understand everyone's problem with the tiles. I love 'em and would never replace them! :)
Looks awesome. When I scrolled down to the photo of the old toilet seat, I literally wiped my computer screen thinking I had something on my screen! Ha! Hasta la vista old toilet! Love this. Now I am so embarassed I have a brown bath mat in my bathroom…..http://chrislovesjulia.blogspot.com/2010/11/bathroom-refresher.html…..eeeks.
We're in the middle of making some cosmetic changes to our bathroom. So far we've removed the dated medicine cabinet, added some open shelving, replaced the shower head/sink faucet, and painted the vanity. It's actually been a pretty dramatic change for very little money which makes me happy!
When we have guests I make sure to fill a small basket with shampoo, conditioner, body lotion, toothpaste, new toothbrush (still in package), floss and pain reliever. We have cotton rounds and q-tips in glass containers on shelves (easily visible) and put out fresh towels/washcloths. I also like to put a fresh roll of toilet paper on the roll so hopefully guests won't have to go searching for more!
I will be watching these comments are we are about to gut our guest bath (because in addition to yellow tile, we also have a yellow toilet, a yellow tub, yellow sinks, and pinkish countertops -lovely!). The two requests I've received that haven't been mentioned above are a hand mirror (so my mom can see what the back of her hair looks like) and a hair dryer (so guests don't have to keep borrowing mine).
I totally agree with Amanda. Get a nicer shampoo, conditioner, soap, body wash than you normally use. Even if you don't use body wash (I don't), lots of people do. So get it anyways :) I also put a nice hand soap and hand lotion on the sink. Good luck! Hope they love your new house!!
I LOVE the combo! Perfect! I knew you two wouldn't disappoint!
I got a chuckle out of the "Fashion Show" Sherry! Do you do the same thing when you purchase new clothing? Every time I go on a clothing/shoes shopping spree, whether for me, my boyfriend, well anybody…when we get home I yell "Fashion Show!" and have to have a fashion show in the living room!
LOVE IT!!! Girl after my own heart! My boyfriend usually first rolls his eyes (if he's the one with the new threads), and then gives me a look like "Seriously" but he'll do it for me anyway. :) Can't wait to have kids! They'll be my real live little fashion plates!
Someone mentioned fresh flowers, which I totally echo – along with some reading material (although let's be honest, if your parents are staying there, the only things they'll want to read are baby books to Clara!). Maybe a candle. And personally I LOVE it when a guest bathroom has its own hair dryer.
Great choice on the shower curtain!
Though I don't travel super frequently, I have had several hotel stays in the last 2-3 years. Since I always pack my own shampoo, etc. I never need the hotel-supplied toiletries. BUT I do bring them all home with me — to keep in a nice basket in my guest bathroom. It means there's always a nice variety of stuff to choose from and hey, it's free. I also leave any sample-size toothpaste, floss, etc. in there if I get any freebies at the dentist.
We renovated our bathroom last summer, making sure to keep the original footprint, but demo'ing down to the studs so that we could start fresh. Although it was the world's longest small apartment bathroom reno (4 weeks!), we love the result and are happy that we spent the money on it….pictures on Houzz at the following link:
Buy a second shower curtain and skirt that sink. You can also cut 'ribbons' of fabric from the shower curtain and sew bands onto towels. Might be too matchy matchy. I have heard about spraying shower enclosures and tiles floors — similar to having a pink bathtub redone in white. I'm doing that with my master shower. I can't afford a total total overhaul so I'll have all the tile sprayed white to revive it. I like the medallion curtain a lot. I think you should buy a few of those and use them as fabric in the room (e.g. curtain panels, cushions, pillows, etc.
You guys, I'm not gonna lie – I LOVE your yellow and beige tiled bathroom. As far as mid century bathrooms go, this may be the easiest color combo to modernize with accessories. I know that these bathrooms from the olden days aren't for everyone, and you guys have plans to make this room your own. But I'll enjoy your pictures of those tiles for now!
I say extra points for folding towels in the shape of a swan or another animal in the bathroom. :)
I think guest bedrooms should not be without a clock. But let me give you a few tips. DO NOT buy a clock that cannot be seen at night, or that makes click click noises every time the second hand moves. I speak from personal experience that this is extremely annoying to your guests who may wake up when it is still dark out, wonder what time it is but not be able to see the clock without turning on a light (which you can't do if there is more than one person in the room), and then trying to go back to sleep only to hear that dang ticking noise over and over! :-)
I love it all! I just started a big bathroom project. I'm removing black wallpaper. I'm trying to transform my bathroom from a dark cave, to relaxing spa. So far it's taken me a bucket of worm water, a sponge, and lots of patients.
PS – I love the shower curtain, and am so glad you tried the striped mat too. It is by far the best choice!
Here's our (not so) recently finished bathroom: http://house-of-boys.livejournal.com/108938.html (I'm more like 29 weeks pregnant now!) Also, I wish I had thought to close the toilet lid. My bad!
I always keep a few girly products stocked in our bathrooms- so guests won't have to ask. Things like tampons, a hair dryer, room spray.
Thanks for the reply, Sherry! By no means was I wanting to pressure, but just a HUGE YHL fan!! I consider it such a joy to get to peep in on diy DAILY! It is like the best home magazine, just FREE!
I totally agree. Best magazine ever! Worth more than what I pay for my monthly mag. subscriptions
LOVE the shower curtain!
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A fun raffle game organized by the City of Cambridge!
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By MATTHEW STEVENS
By GWEN SISSON
By PAUL SIMS
Community leaders continue to take steps toward addressing what a professional panel recommended recently as ways to move the cityŌĆÖs core forward.
By JOEL COLEMAN
By DANNY P. SMITH
Jack G.
MABEN ŌĆö Charles Bruce Allen, 74, passed away on April 8, 2011, at North Mississippi Medical Center in Eupora.
Larry Louis Lolley, 78, passed away on April 7, 2011 at home after a brief illness.┬Ā
Funeral services for John Louis Peterson will be held at 11 a.m. April 9 at New Zion United Methodist Church with Rev. Tyrone Stallings officiating.
Funeral services for Ruzell Melvin Poe will be at 3 p.m. Saturday, March 9, at Rockhill United Methodist Church with Rev. Jerome Wilson officiating.


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I like my 17 hmr. I head shoot rock doves, cotton tails and blue grouse with it up to 150 yds or so, out here in the Olympics. I can't do that consistently with my 10/22.
The most fun at the range is my GSG5.
Thomas Jefferson: "The laws that forbid the carrying of arms are laws of such a nature. They disarm only those who are neither inclined nor determined to commit crimes....Such laws make things worse for the assaulted and better for the assailants; they serve rather to encourage than to prevent homicides, for an unarmed man may be attacked with greater confidence than an armed man. Thomas Jefferson's "Commonplace Book,"
The desk was "extra" at work...I took it home, a double desk...face-to-face...made of oak.
Mine's not going to appraise too high...but it's great!
I like my Henry .22 magnum pump (H003TM) with Zeiss 4x 32. It is very
accurate and feed problems are not an issue.
A Zeiss on a Henry! That's the first I've come across that! Now that's some quality glass on the rifle!!!
Much to be said for a Calico carbine
100 rounds of fun per magazine
Calico Specialist
Marlin Specialist
I'm not just Trigger Happy, I'm Trigger Ecstatic!!
I've been lurking here for a while and thought I'd jump in here. My favorite .22 is my Ruger Charger. Done all of the work on it myself. Just installed a Mueller 4.5X14 scope on it. Can't wait to see what she'll do now.
I enjoy my Ruger 10/22 because it is so versatil I can set it up a number of ways and go high tech low tech or even mad man and turn it into a assualt rifle and look at all the different Mags from standered to high capacity Mags
Mine is kept pretty easy I put a set of Fiber optic sights on it as I am a old man and need a little more for the eye balls to see down range I bulit one for the wife getting her a Bull barrel a thumb holl stock for comfort and a slightly expensive scope ( 60 bucks ) and a few other after market items and she loves hitting targets over a hundred yards What other 22 cal rifle can you do so many different things with and do it on a low budget ??? keep it down range and enjoy each shot guys
A fellow Ruger fan my compliments on your work looks sweet bet it is pretty accurate as well and best of all cheap to shoot all day
Marlin 60 I modified the stock on for my nephew.
This one is very accurate and fun to shoot too.
I wish we could still get semi-autos down here... My favourite is my CZ 452 Varmint Nickel in 17HMR.. With my new Wolf-Eyes torch and hollow points it is deadly on foxes out to 150 metres


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Kamnik - Youth Hostel Pod Skalo
A lovely family-run hostel located in the heart of Slovenia, close to the nature. Enjoy homely atmosphere at the house with old time-touch, taste great breakfast and discover Slovenia!
From €14.00
From €30.00
Welcome to our hostel
Vesna Resnik
Around the hostel
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Kamnik. Another world. So close.
Kamnik is one of the oldest Slovene towns, situated at the foot of the Kamnik Alps, offering its visitors many adventures - not only in its old town center but also in its picturesque surroundings with breathtaking views, unspoiled nature and well preserved cultural heritage. Kamnik is a town of kind people, tradition, history and wealthy heritage with a warm soul, to which you are kindly invited, for a stroll through its riches and its beautiful surroundings.


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Everything was fantastic! The ambience, the food, the service. I will be back!
Try the Habanero soup, the injected Salmon, the tuna sashimi, the coal filet, or the blacken fish. So good!
If you own or manage MB, register now for free tools to enhance your listing, attract new reviews, and respond to reviewers.


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These red round table covers are great for any event. The table cover is plastic making spills less of a worry. The covers make for an easy clean-up. They fit most standard round tables. Disposable for easy clean up and great to color coordinate with your party decor. Includes 1, 84" round plastic table cover.
" Thank you so much. I really love your store and think its great i can cruise around online. I really appreciate what you've done, I feel great about... "


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Merran Smith of Clean Energy Canada (the spawn of the tendrilous and pervasive eco-activist group Tides Canada and Simon Fraser University) and one of the dozens of Metro Vancouver leaders pushing for...
A new series of cemetery and haunted pub tours this fall should give fans of the paranormal their ghostly fix leading up to Halloween.
Join Calgary-based spiritual guide and medium Niki Berthelette, the star of Access Television's paranormal series The Intuitives (airing Sundays at 6:30 p.m.), as she leads the new Twilight Cemetery and Calgary Haunted Pub tours.
Berthelette will lead the a series of three-hour Friday night Twilight Cemetery tours ($40 per person; weather-dependent) through Union Cemetery.
Berthelette, a professional spiritual medium for the past eight years, promises to teach guests cemetery etiquette and how to get the paranormal-most out of a cemetery walk.
Haunted Pub tours ($30 per person) are scheduled to visit three Calgary pubs over four to five hours on Nov. 1.
Two of the pubs, The Cat & Fiddle and The Rose & Crown, used to be funeral homes. Legend has it these bars are now haunted by long-gone regulars, bartenders and even ex-morticians.
The third pub on the tour, The Hose & Hound, is rumoured to be haunted by stomping horses and a swooping monkey, animals that used to live in the former fire hall.
At each pub, Berthelette will explain the pub's history, along with paranormal skills such as capturing an "orb" with a digital camera.
At the Hose & Hound, guests will make and use their own dowsing rods (to try to find the monkey of course).
There will also be a special five-hour "Day of the Dead" Hybrid Tour ($75, including dinner at The Cat & Fiddle) that visits two of the haunted pubs and a local cemetery.
For more details, or to register, call 403-289-5303, or visit the Calgary Haunted Pub Tour Facebook.com page.
The biggest sale of the year, on now! Find almost $4 million worth of items such as cars, trips, furniture, gift cards and more at discounts of up to 50% off. Don't miss out as savvy shoppers will move fast to take advantage of these deep discounts. Sale ends Wednesday, April 1, at 9 p.m. Like it? Buy it before its gone. Brought to you by The Vancouver Sun and The Province.