text:
Original Article
5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo
Article first published online: 17 NOV 2010
DOI: 10.1002/ana.22234
Copyright © 2010 American Neurological Association
Annals of Neurology
Volume 69, Issue 1, pages 34–46, January 2011
Additional Information
How to Cite
Chu, J. and Praticò, D. (2011), 5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo. Ann Neurol., 69: 34–46. doi: 10.1002/ana.22234
Publication History
- Issue published online: 28 JAN 2011
- Article first published online: 17 NOV 2010
- Manuscript Accepted: 20 AUG 2010
- Manuscript Revised: 4 AUG 2010
- Manuscript Received: 30 JUN 2010
Funded by
- National Institutes of Health (NIH)
- National Institute on Aging. Grant Numbers: AG-022152, AG-033568
- Alzheimer's Association Zenith Fellowship. Grant Number: ZEN-07-59289
The 5-lipoxygenase (5-LO) enzymatic pathway is widely distributed within the central nervous system, and is upregulated in Alzheimer's disease. However, the mechanism whereby it may influence the disease pathogenesis remains elusive.
We evaluated the molecular mechanism by which 5-LO regulates amyloid β (Aβ) formation in vitro and in vivo by pharmacological and genetic approaches.
Here we show that 5-LO regulates the formation of Aβ by activating the cAMP-response element binding protein (CREB), which in turn increases transcription of the γ-secretase complex. Preventing CREB activation by pharmacologic inhibition or dominant negative mutants blocks the 5-LO-dependent elevation of Aβ formation and the increase of γ-secretase mRNA and protein levels. Moreover, 5-LO targeted gene disruption or its in vivo selective pharmacological inhibition results in a significant reduction of Aβ, CREB and γ-secretase levels.
These data establish a novel functional role for 5-LO in regulating endogenous formation of Aβ levels in the central nervous system. Thus, 5-LO pharmacological inhibition may be beneficial in the treatment and prevention of Alzheimer's disease. Ann Neurol 2010


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Kingston City Council members will have extra insight into city budget matters throughout the fiscal year after they passed an ordinance establishing a financial review committee.
According to Mayor Troy Beets, the committee will have no decision-making power, but will act as a liaison between council and city financial planners. The committee will consist of two council members, the city manager, the city budget officer, plus an administrative employee.
Council members Tony Brown and Norman Sugarman will be the first councilmen to serve on the committee. The votes on their appointment, as well as the vote establishing the committee, were all unanimous.
In other council business, council passed on second reading an amending to the city ordinance to remove domicile and residency questions on liquor license applications.
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Wesley Gryk, senior partner and founder of the firm, is a dual British-American national and has practised law in both countries. He obtained his BA(Hons) from Harvard College and his JD(Hons) from Harvard Law School. He also attended the University of Warsaw for one year on a Fulbright Fellowship. He began his legal career as judicial clerk to the late Honorable Constance Baker Motley, US District Judge in the Southern District of New York (Manhattan), who was the first black woman appointed to the US Federal Judiciary. He went on to work for four years for Shearman and Sterling, a large New York corporate law firm, first in New York City and then in Hong Kong.
He moved to the United Kingdom in 1980 to take up the post of Deputy Representative and Legal Adviser to the United Nations High Commissioner for Refugees and went on to work in London for the International Secretariat of Amnesty International for five years, first as its Deputy Legal Adviser and then as the Deputy Head of the organisation's research department. After retraining to become a solicitor in this country, he worked for a number of years with the highly respected civil liberties lawyer Ben Birnberg of B.M. Birnberg and Co, before setting up Wesley Gryk Solicitors in 1995. Wesley served two terms as a member of the Law Society Council, the governing body for solicitors in England and Wales, with responsibility for immigration matters. He also previously was a board member of the Refugee Legal Centre, the Redress Trust and the Legal Aid Practitioners Group. He has travelled extensively on international human rights missions having, for example, attended the trial of Saddam Hussein in Iraq and of Abdullah Ocalan in Turkey on behalf of Amnesty International and the trial of former Deputy Prime Minister Anwar Ibrahim in Malaysia on behalf of Human Rights Watch. He was involved in much of the litigation, campaigning and lobbying which resulted in the implementation of the current unmarried partners and civil partnership rules and he continues to undertake voluntary work on these issues.
His practice covers the full range of immigration issues and, in particular, his strength in gay rights cases is well acknowledged. He has represented the UNHCR in two important House of Lords cases relating to immigration law - Shah and Islam, about the persecution of women in Pakistan, and Sepet and Bulbul, relating to conscientious objection in Turkey.
Alison Hunter, who became a partner in the firm on 1 October 2006, was educated in Switzerland, Germany and the United Kingdom. She read law with French law at King's College, London and went on to do a Masters degree in Human Rights Law at University College, London. After her training at Freshfields, she joined Wesley Gryk Solicitors in 1997 as a solicitor. Her practice covers all aspects of immigration and nationality law, with particular emphasis on EU free movement law, asylum and human rights law. She maintains close links with German lawyers and academics working in the field of immigration. She was formerly a visiting lecturer for immigration law at Westminster University and a Management Committee Member of the Centre for Advice on Individual Rights in Europe and a board member of the Immigration Law Practitioners' Association.
Barry O'Leary, who became a partner in the firm on 1 October 2006, read law at Cambridge University and attended law school at the College of Law, London. He qualified as a solicitor in 1997 and joined Wesley Gryk Solicitors in January 2000. His practice deals with the full range of immigration and nationality issues, with a particular emphasis on applications based on same sex relationships and also on asylum and human rights claims on the basis of sexual orientation. In his spare time, he works as a volunteer lawyer providing legal advice on these issues. He was heavily involved in the consultation process leading up to the introduction of the Civil Partnership Act 2004 and has given a number of lectures on the immigration aspects of this Act. He is the author of the immigration chapter of the Law Society Publication "Civil Partnership – the Law in Practice".
Tim Barnden read English at Cambridge University and converted to Law studying at the College of Law in London. He qualified as a solicitor in 1998 and has specialized in immigration and asylum work since then. He undertakes advice and representation across the full range of immigration and asylum law. He has recently been elected Chair of the UK Lesbian and Gay Immigration Group (UKLGIG) and is involved closely with their asylum project. He was an Executive Committee member of the Immigration Law Practitioners Association (ILPA) for the years 2007-9. He also continues to undertake and is known for his training work.
Diana Baxter joined Wesley Gryk Solicitors as a paralegal in 2008 and qualified as a solicitor in 2012. Prior to joining Wesley Gryk, Diana obtained a 1st class honours in Chinese Studies from the University of Oxford, following which she worked in Beijing as a paralegal. Diana subsequently achieved a distinction MSc in Development Studies at the London School of Economics, and spent a period undertaking postgraduate studies in sociology of law and migration at the University of California.
Diana's practice covers a wide range of immigration and asylum law, with a particular interest in British nationality law. She is an active member of the Immigration Law Practitioners Association (ILPA) and has represented ILPA on visits to the Home Office as part of the Complex Casework Partner Forum, as well as co-teaching an ILPA course on the financial requirements under Appendix FM. Diana is also a volunteer adviser at the Project for the Registration of Children as British Citizens and, in 2014, she participated in an expert panel on international surrogacy at the Alternative Parenting Show, London.
Adam qualified as a solicitor in 2012. He read law at the London School of Economics, graduating in 2008. He has worked for the firm for over four years and, for most of that time, he has worked directly with Barry O'Leary. Adam is a volunteer for the UK Lesbian and Gay Immigration Group where he speaks at the partnership and asylum meetings. Adam was also a volunteer for the Terrence Higgins Trust for over twelve months where he worked as a Refugee Mentor offering advice and support to asylum seekers in the UK. Adam offers advice and representation across the full range of immigration and nationality matters.
Elizabeth is qualified as a solicitor as well as an Attorney-at-Law in the State of New York. She first practiced immigration law in the US in 1996, and in the UK in 2007. Elizabeth is a native of New York City, and has lived in Germany and Italy as well as the UK. She was educated at Harvard University, Boston University, and the London School of Economics. After graduating from law school, she clerked for Hon. Nancy Gertner on the Federal District Court for the District of Massachusetts, before joining the Immigration Group at Dechert Price and Rhoads in Philadelphia. Since moving to the UK, she has practiced immigration and asylum law at Elder Rahimi Solicitors and Refugee and Migrant Justice. In addition to preparing asylum and immigration applications, she has represented her clients as an advocate before both the First Tier and Upper Tribunal, Immigration and Asylum Chamber.
Irena qualified as a solicitor at Wesley Gryk Solicitors in late 2014. Irena is originally from Armenia and has also lived in Russia and Bulgaria. She has a basic understanding of the Armenian language and is fluent in Russian and Bulgarian. Irena read law at the London School of Economics, graduating in 2009. She joined Wesley Gryk Solicitors as a paralegal in the same year and has now worked for the firm for over five years. Alongside her work at the firm, Irena has also participated in an international research project on immigration and asylum law on behalf of the London School of Economics. Irena offers advice and representation across the full range of immigration, asylum and nationality matters, with a particular emphasis on family immigration matters.
Tom Hardwick is a trainee solicitor at Wesley Gryk Solicitors. Tom read International History and International Politics at the University of Sheffield. He was awarded a BA degree in 2008. He went on to obtain a Graduate Diploma in Law from The College of Law. He started working as a paralegal at Wesley Gryk Solicitors in August 2011. For most of his time at the firm he has worked directly with Wesley Gryk. Tom is currently studying the Legal Practice Course part-time while working at Wesley Gryk Solicitors. He expects to qualify as a solicitor in early 2015.
Emily Heinrich has been with the firm since 2009 and qualified as a Solicitor in early 2015. Emily studied on the International Baccalaureate programme in The Netherlands and went on to read Law at the University of Surrey where she was awarded her undergraduate degree in 2007. Emily continued her legal education at the University of Surrey, graduating with a Masters in International Law, for which she was awarded a Distinction. Her LLM dissertation, titled "Universalism and Cultural Relativism: In Search of Reconciliation", focused on the development of international human rights, a subject in which she retains an active interest. Emily completed her Legal Practice Course at the College of Law, Guildford.
Chambers Guide to the Legal Profession ranks Wesley Gryk Solicitors LLP equal first amongst personal immigration practices in London. Wesley Gryk, Alison Hunter, Barry O'Leary and Tim Barnden are all named as leading individual practioners.
If you think we can help
you with your immigration
situation, your first step should be to contact us to make an appointment. Click here
Changes to the Knowledge of Language and Life in the United Kingdom requirement for settlement and naturalisation applications
The Home Office has recently announced that from 28 October 2013, all applicants for settlement or naturalisation will need to meet a new, two-part Knowledge of Language and Life in the United Kingdom requirement (unless exempt)…read more
Barry O'Leary. Partner, has been appointed to the Law Society Immigration Law Committee.
On 11 July 2013, Barry O'Leary taught the ILPA course on Applications for leave to enter: the general grounds for refusal, mandatory bans, significant contrivance and suitability.
The All Parliamentary Group's report on family migration was published today here.
It includes thanks to Barry O'Leary for his input.
Wesley Gryk, Senior Partner, was one of eight leading immigration lawyers invited by the Law Society Gazette to participate in a roundtable discussion regarding the growing difficulties facing immigration practitioners as a result of the political debate surrounding immigration. See article here.
The firm played key roles in helping to celebrate the 20th anniversary of the UK Lesbian and Gay Immigration Group with a party held at the Royal Vauxhall Tavern in May 2013, with Barry O'Leary helping to organise the event and Tim Barnden and Wesley Gryk speaking at the celebration.
On 15 March 2013, four of our solicitors were named as "Super Lawyers" in the new magazine of that name.
On 14 March 2013, Wesley Gryk, Senior Partner, spoke to the Lewes Immigration Detainee Support Group and the Lewes Amnesty International group on recent legal developments with respect to lesbian and gay asylum seekers.
Barry O'Leary, Partner, appeared as a panellist at University College London, on 15 February 2013, for the debate on "When should LGBT people be offered Asylum in the UK?".
Barry O'Leary, Partner, gave oral evidence in Parliament, on 11 February 2013, to the All-Party Parliamentary Group (APPG) on Migration inquiry into family migration rules, on behalf of ILPA.
Tim Barnden, Senior Solicitor, spoke on 23 January 2013 at the AIRE Centre's seminar on Family Reunification to mark the publication of its report "Family Reunification Requirements: a barrier or facilitator to integration?".
Alison Hunter, Partner, met the Home Office as part of an ILPA team to discuss the rules relating to international adoption.
Tim Barnden and Katie Dilger taught an ILPA course on the financial requirements of the new immigration rules relating to family members in London on 4 December 2012.
Tim Barnden, Senior Solicitor, spoke at "A consideration of the family migration changes and Article 8: Where do we go from here?", a joint Justice, Human Rights Lawyers Association and ILPA event held on 8 November 2012.
Tim Barnden and Katie Dilger spoke at the ILPA AGM on 17 November on the new family immigration rules.
Katie Dilger taught an ILPA course on the financial requirements of the new immigration rules relating to family members in London on 21 September 2012.
Alison Hunter, Partner, attended a meeting on behalf of ILPA with the European Section of the UKBA regarding the legal issues arising out of recent amendments to the Immigration (EEA) Regulations and clarifying the UKBA's position following some important cases in the Court of Justice of the European Union.
Wesley Gryk, Senior Partner, was chosen for inclusion in the 2013 volume of Debrett's People of Today and in a number of other legal and and Who's Who directories.
Barry O'Leary and Tim Barnden taught an ILPA course on the new immigration rules relating to partners in London on 17 July 2012, in Birmingham on 23 July 2012, and again in London on 16 August 2012.
Barry O'Leary, Partner, met with the UKBA as the ILPA representative on the Case Assurance & Audit Unit Partner forum and in connection with the new immigration rules relating to family migration.
Katie Dilger, Solicitor, was elected to the Executive Committee of the Immigration Law Practitioners' Association (ILPA) in November 2011. ILPA seeks to promote and improve advice and representation in the fields of immigration, asylum and nationality law. ILPA's work includes providing training sessions for practitioners, disseminating information, participating in Governmental meetings and consultations and briefing MPs. The firm is actively involved with ILPA's work by, amongst other things, providing training, participating in subcommittees and responding to consultations. Katie is also an active member of ILPA's Family and General Subcommittee.
Tim Barnden, Senior Solicitor, was elected chair of the board of trustees of the UK Lesbian and Gay Immigration Group (UKLGIG). UKLGIG promotes equality and dignity for lesbian, gay, bisexual and transgender (LGBT) people who seek asylum in the UK, or who wish to immigrate here to be with their same-sex partner. Tim has volunteered with the charity since 2005 in their asylum support work. Tim is looking forward to further involvement with UKLGIG and assisting them in their mission of providing support to LGBT asylum seekers.
Wesley Gryk Solicitors LLP
140 Lower Marsh
E-mail - email@example.com
Fax - (020) 7261 9985


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He's a comic at heart, and Foxx had us rolling in this 2004 romantic film....
He's a comic at heart, and Foxx had us rolling in this 2004 romantic film. Gabrielle Union and Morris Chestnut joined him in the feel-good story of love. We hope the fellas were taking notes.
F. Gary Gray on directing Jamie Foxx in 'Law Abiding Citizen' »
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The New York Times Biographical Service, Volume 32
New York Times & Arno Press, 2001 - Biography
A compilation of current biographical information of general interest.
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Kentucky Fried Chicken: Brain or kidney?
For those fast food skeptics out there, the Colonel may have just cemented your doubts regarding what you might be eating.
Ibrahim Langoo, 19, is undoubtedly at the forefront of this conversation after discovering what appeared to be a "wrinkled brain" where his KFC Gladiator meal box was supposed to be.
According to the Daily Mail, even though the first piece of chicken appeared to be normal, he immediately became nauseated after pulling the bone off the second.
"I have a habit of picking the chicken off the bone with my fingers, and as I pulled the second piece apart I saw this horrible wrinkled foreign body."
After his initial repulsion, Langoo photographed the chicken at the branch in Colchester, Essex. KFC's experts subsequently contested the item in question was in fact a kidney.
In the eyes of the consumer, does it really matter whether it was a brain or kidney? When you order chicken from KFC, you expect to get chicken.
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Founded in 1787, Marylebone Cricket Club is the most active and famous cricket club in the world and owner of Lord's Cricket Ground - the Home of Cricket.
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England's archers have been in golden form at the Commonwealth Games in Delhi, with the 2012 Olympic event at Lord's now less than two years away.
Sachin Tendulkar's stunning century against Australia made good on his insistence to still be hungry for more runs as the India batsman notched his 49th Test century in Bangalore.
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Founded in 1787, Marylebone Cricket Club is the most active and famous cricket club in the world and owner of Lord's Cricket Ground - the Home of Cricket.
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Six indicted in New York for involvement in StubHub cyber fraud
New York - Six people were indicted in New York for involvement in a global cybercrime ring that took over more than 1,000 accounts of eBay Inc's StubHub online ticket reselling service, according to a statement released by the office of Manhattan District Attorney Cyrus R. Vance Jr.
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Home > All Cities > Elgin, Illinois Real Estate Listings > West Point Gardens Subdivision
Properties for sale in the West Point Gardens Subdivision, Elgin, Illinois
Properties 1 to 5 of 5
291 Garden, ELGIN, IllinoisList Price: $349,900 | Bed:3 | Bath:3.10
Better than new construction! Multi-generational living with in-law suite has full kitchen,bdrm,bath& Liv.rm in fin.bsmt.1st fl master suite. Model home decor w/Open floor plan.2 bedrooms up w/loft (easily converted to 4th bdrm).No expense spared offers granite,hardwood flrs, lighting, solid doors,etc. Brick exterior. Landscaped, privacy fenced yard.Across from park, easy access to major highways,schools & shopping Vaulted/Cathedral Ceilings,Hardwood Floors,1st Floor Bedroom,In-Law Arrangement,1st Floor Laundry,1st Floor Full Bath 2nd Kitchen,Exercise Room,Loft,Recreation Room,Walk In Closet Balcony,Patio,Porch,Brick Paver Patio Circuit Breakers,200+ Amp Service Oven/Range,Microwave,Dishwasher,Refrigerator,High End Refrigerator,Refrigerator-Bar,Washer,Dryer,Disposal,Wine Cooler/Refrigerator Corner,Landscaped Professionally KRt20 to Nessler to Gansset west to Garden.
Listing Office: RE/MAX Great American North | MLS ID#: 08738309
222 MIDDLETON, ELGIN, IllinoisList Price: $269,177 | Bed:3 | Bath:2.10
Everyone wants NEW!Be the 1st owner of this beautiful Birchwood Model w/premium lot close to Meier Park!Upgraded Charming Elevation!Full Basement w/full bath rough-in ready for you to finish!Amazing family size kitchen is the heart of this home!Huge center island, double pantry,hardwood floors & stainless steel appliances! Master Bedroom w/Spa-like private bath!Desirable 2nd level laundry!Huge loft ez 4th bed convert Hardwood Floors,2nd Floor Laundry Breakfast Room,Foyer,Loft Porch Circuit Breakers,200+ Amp Service Oven/Range,Microwave,Dishwasher,Disposal,All Stainless Steel Kitchen Appliances Landscaped Professionally ROUTE 20 & RANDALL RD WEST TO NESLER RD, SOUTH TO DAISEY RIGHT TO GARDEN LEFT TO SALES OFFICE!
Listing Office: Keller Williams Infinity | MLS ID#: 08820582
292 Longview, ELGIN, IllinoisList Price: $250,000 | Bed:3 | Bath:2.10
Beautifully UPGRADED Georgetown, CUSTOM paint & window treatments, ceiling fans and more! Awesome upgraded OPEN kitch w/42" cabs, HW flrs, breakfast bar & ALL appls! Kitch opens to AWESOME great room! Formal separate DINING rm! Huge 1st flr ldry! Master Bed w/ walk in closet, dbl sinks, sep shower & soaking tub! Unfinished 9'bsmt! OVER 20K in UPGRADES! Why wait for new construction? MOVE IN NOW for LESS! PERFECT! Vaulted/Cathedral Ceilings,Hardwood Floors,1st Floor Laundry No additional rooms Oven/Range,Dishwasher,Refrigerator,Washer,Dryer,Disposal Fenced Yard Route 20 West of Randall to Nestler turn south to Daisy right than left on Longview to home
Listing Office: RE/MAX At Home | MLS ID#: 08831914
3607 DAISY, ELGIN, IllinoisList Price: $239,900 | Bed:3 | Bath:2.10
3 BEDROOMS, 2.5 BATHS WITH ATTACHED 2-CAR GARAGE. A TWO-STORY FOYER, TURNING STAIRCASE, LIVING ROOM AND FORMAL DINING ROOM ALL WELCOME YOU TO THIS GRACIOUS FAMILY LIVING. THE FIRST FLOOR HAS 9' CEILINGS THROUGHOUT. BOASTS A BRIGHT EAT-IN KITCHEN, THREE LARGE BEDROOMS, A PRIVATE MASTER BATH ALSO A PRIVATE COVERED FRONT PORCH. Hardwood Floors,2nd Floor Laundry Breakfast Room,Recreation Room Porch,Storms/Screens Circuit Breakers,200+ Amp Service Oven/Range,Dishwasher,Refrigerator,Washer,Dryer,Disposal Landscaped Professionally ROUTE 20 & RANDALL RD WEST TO NESLER RD, SOUTH TO DAISY, WEST TO GARDEN, PARK ON GARDEN TO ACCESS SP
Listing Office: Residential Real Estate Svcs | MLS ID#: 08862116
3618 Daisy, ELGIN, IllinoisList Price: $200,000 | Bed:2 | Bath:2.10
Fabulous Family home w/beautiful floor plan!A/C included! 9' Ceilings on main level! Spacious Living & dining room open to fantastic kitchen with popular Cherry Finished Cabinets,huge island & stainless steel appliances!Desirable covered front porch! Full Basement w/finished family room/rec room!Excellent Master Suite w/private bath and walk-in closet.Loft is easy 3rd bedroom convert. Lawn/Snow care no worries! Vaulted/Cathedral Ceilings Eating Area,Foyer,Loft Porch,Storms/Screens Circuit Breakers Oven/Range,Dishwasher,Disposal Landscaped Professionally RT 20 & RANDALL RD WEST TO NESLER RD, SOUTH TO DAISY,
Listing Office: Keller Williams Infinity | MLS ID#: 08823448


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Discrete Manufacturing: Using Microsoft Dynamics AX 2012
October 20, 2013
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[WIN 8] HP M6-1188ca Recovery Discs needed, will pay if necessary
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So I bought this laptop which comes with Windows 8, so I let Windows Update run, and when resets, doesnt boot up anymore, so I tried the system recovery. That make the system to show me an error of "No bootable disk found" shows up. (Maybe because I have made 2 partitions earlier?)
And now I installed back a trial copy of Win 8 which will work for 90 days, but want to have my original system back, I need the recovery discs for that because the Partition doesnt work, do any of you have it or can get it? Im willing to pay for it, I cant get it from HP because they only ship to USA or Canada, Instead I want to download the discs because I'm in Argentina
Or, do you know another option so I can get my laptop running again? I use it to work everyday, and by know I have 13 days behind my deadlines.. Thank you very much
Re: [WIN 8] HP M6-1188ca Recovery Discs needed, will pay if necessary
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The only thing I can think of that you can try is to download the W8 ISO file from the link below and see if the product key encrypted in the BIOS works with the file.
It should.
You downloadd the W8 x64 ISO file, and then you use the W7 ISO to DVD/USB flash drive tool to make the ISO file bootable onto a DVD or usb flash drive.
W8 x64 ISO file:
ISO to DVD/USB tool:


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Ashes to Diamond
Junior Member
Why no mention of Morgana and Kayle? But they talk about Lux and Garen being the first? Not even close.
Yay! We're not getting another freakishly busty lady. Of course I still wouldn't be surprised if, in the near future, Riot creates a champion called something like, "Joanna the Porn Star" Really, some of us would rather not see all of that unrealistic grossness. Well that's my rant cool-looking design by the way!
Senior Member
looks too much like nassus imo.... though maybe the colors will deferenciate the two a little more.
Krimson Flame
What about Morgana and Kayle?
Arkhaios Daimon
Haha, his face looks like a crocodile, no, not an alligator for all you US people, a crocodile.
Souul Reaper
I'm DEFINITELY getting this champion!!!
When the sneak peak was first posted he was the Eater of souls, why the name change? I thought it was an awesome name.
Danny The Divine
Renekton vs. Nasus who will prevail?
nasus 2.0
What happened to his appetite for souls?
© 2015 Riot Games, Inc. All rights reserved. Riot Games, League of Legends and PvP.net are trademarks, services marks, or registered trademarks of Riot Games, Inc.


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CFIers Join Leading Secularists in Pondering the Future of Humanism
Democratic Discourse with Michael De Dora
August 30, 2010
Ron Lindsay and I contributed to a collection of essays on humanism featured on the Web site Patheos.
Adult Reasoning About Embryos
No Faith Value with Ronald A. Lindsay
August 27, 2010
Religious dogma obstructs research ... again
Read more… | 10 Comments
An Immodest Proposal for Ground Zero
Hollywood Reality Check with Jim Underdown
August 26, 2010
Our record in the Muslim-Christian feud is clean. We are neither Montague nor Capulet.
Read more… | 4 Comments
Jersey-Devil Expedition
Investigative Briefs with Joe Nickell
August 26, 2010
Where the devil was the creature?
Are Brains Destined for Religion?
It's Only Natural with John Shook
August 25, 2010
Scientists are so impressed by natural explanations for religion that they make religion sound unavoidable.
Read more… | 6 Comments
On what principles can we oppose the Islamic Center at Ground Zero?
Dino from the Sands with Ibn Warraq
August 25, 2010
Is there a legal argument to block the building of the Islamic Center at Ground Zero?
Read more… | 50 Comments
On What Should Politicians Base Their Decisions?
Democratic Discourse with Michael De Dora
August 24, 2010
This question comes up in nearly every political debate, and cuts to the very root of an elected official's responsibilities.
Judge Halts Stem Cell Research Funding
Reasonable Doubt with Derek C. Araujo
August 23, 2010
A federal district judge ruled that all embryonic stem cell research is an illegal violation of the Dickey-Wicker Amendment.
Read more… | 4 Comments
Operation Unity: Opposition Through Action
Freethought from the Heartland with Reba Boyd Wooden
August 21, 2010
A rally to protest a visit by Sheriff Joe and to celebrate diversity.
The Armageddon Comes to Ottawa
True North Strong & Free Thinking with Justin B. Trottier
August 21, 2010
Exposing the dangerous connection between Canadian Christian nationalists and high-ranking politicians
Read more… | 2 Comments


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Natural habitat for the 'bright indirect light' bulbs?
Many S.A. natives thrive here in Southern California. (Same climate, I presume.) Seems many of the bulbs (Clivia, Haemanthus, etc.) need bright indirect light to be happy. Where do they grow naturally that would satisfy (or cause) this predeliction? Are there lots of broad, canopy trees they grow under?
Clivias are easy to place, as few plants here will bloom in such low light while tolerating our heat. Where would a Haemanthus appear in nature, for example? And how much light will it tolerate before the leaves fry? It seems to struggle in full shade.
Thanks for the geography lesson.
Here is an article about clivias here. Clivias (with the exception of a single newly discovered species) are native to eastern parts of South Africa where the rainfall comes mostly during the summer (the opposite of our conditions). Haemanthus are native to exposed locations in the Western Cape but are dormant during the summer drought when light intensities and temperatures are at their highest.
Clivias can also be found on the margins of woodlands settings where there are openings to rivers/gorges, etc which will be less dark than closed canopy forests. Not all Haemanthus come from the winter rainfall areas, several species can also be found in the eastern cape with year round rainfall and on into Kwazulu-Natal, where it is summer rainfall or spring/fall. There are species of Haemanthus which occur along the coast in dense evergreen thicket type vegetation, in summer wet grasslands up in the mountains, and into the northern interior of the country which is hot and wet in summer and cold and dry in winter. The western cape species come from regions with climate and rainfall more similar to southern California, and are more often found growing in full sun. These would include H. sanguineus, H. pubescens, and H. coccineus.
The summer rainfall species of Haemanthus can be found growing in actual forests, they also can occur in subtropical shrub-thicket type vegetation, and higher elevation mountain grasslands.
A couple of good books which might help you with answering such habitat questions is by author Elsa Pooley, A Field Guide to Wild Flowers Kwazulu-Natal and the Eastern Region, and/or South African Wild Flower Guide 7/West Coast, by John Manning and Peter Goldblatt.


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Demon of Doom Child Costume
Haunt the dreams of everyone in your neighborhood when you wear the Demon of Doom Child Costume. This black robe features a hood and belt, complete with gloves and a creepy skeleton half mask.
Royal Sword
Wield your power with authority when you bear arms - this four foot long Royal sword makes it very clear who is in charge. Lead the troops into battle or brandish it against dragons, demons and any other sort of personal foe; complete your costume wit this authentic looking faux weapon.
Brown Demon Horns
Make Up Tips Terrorize the party this Halloween as a true demon with these Brown Demon Horns! These realistically detailed latex prosthetics will allow you to mingle undetected among the Hell dwellers. Attach in an instant with Spirit Gum Adhesive (sold separately). Remember to perfect the look with…
Horse Demon Adult Mens Costume
Giddyup out of that grave and go trick or treating when you wear the Horse Demon Adult Men's Costume. This black robe features a jagged hem and comes complete with a belt, gloves and hooded horse skull mask.
Animated Belly Buster
The Demon Seed comes to life in this incredible Animated Belly Buster! This spectacularly shocking costume is worthy of a place in the Halloween Hall of Horrors. The simple white T-Shirt reveals a deep, dark secret that will kill them - a zombie baby is about to emerge! The Animated Belly Buster is…
Hand Gelatin Mold
Freak out your friends by serving them a thick slice of healthy hand! This hand-shaped gelatin mold is the perfect Halloween party supply, creating a food that's frightening, funny, and yummy. They're sure to "hand" it to you all night for your deliciously demonic dish.
Scary Mary Adult Womens Costume
Even the holiest figures can be possessed by the devil on Halloween! Give it a try when you wear this demented Scary Mary Adult Womens Costume. White gown, gloves, and nun headpiece with attached collar and veil provide a great start to your look. Just don't forget the demonic makeup, not included!
Hellboy Deluxe Adult Plus Size Costume
Dark Horse Comics Hellboy went on to movie fame as a super-strong demon who fights for the U.S. government and himself against dark forces and unknown evil. Raise hell this Halloween in this officially licensed Hellboy deluxe adult plus size costume - believe it or not, he's the good guy!
Sweeney Todd Adult Mens Costume
Beware the demon barber of Fleet Street - Sweeney Todd might just take your head off! This officially licensed Sweeney Todd adult mens costume would do Johnny Depp proud and will sweep the ladies off their feet! Anyone care for a meat pie? They're so very tasty!
Demon of Doom Child Costume
Creep out from the darkest shadows and scare up some Halloween fun in this Demon of Doom child costume. The long black robe features bell sleeves and an ornate skull shoulder and chest piece, complete with a black hood and grinning skull mask.
Demon Vampire Mask
Terrify the neighbors with this creepy Demon Vampire Mask. Yellow skin, sharp teeth and grey hair give this mask a little something extra to complete a vampire costume!
Sequin Red Devil Adult Womens Costume
You may be hopelessly hell-bent, but you're also extremely alluring in the Sequin Red Devil Adult Women's Costume. This fiery red, sequin dress features a tutu skirt, sequined horns and a red necklace.
Passion Fairy Red and Black Adult Womens Wig
Add this pig tailed statement making Passion Fairy Red and Black Adult Womens Wig to any goth, witch, vampire, or evil demonness costume you'd like to complete a truly wicked look.
Devil Pipe
You won't just be blowing smoke when you complete your vampire, devil, Goth or gargoyle costume with this awesome Devil pipe.
Dark Fairy Adult Womens Costume
Answer to the most demonic wishes on Halloween when you wear this Dark Fairy Adult Womens Costume. Black paisley patterned ragged dress and black and white striped tattered wings are mysteriously elegant.
Nobody's Fool Adult Mens Costume
The joke certainly won't be on you wearing this Nobody's Fool Adult Mens Costume! This demonic joker outfit includes hood with black and white checker print/striped collar, skeletal mask, black and white top, pants, and waist tie components to give you the full eerie effect.
The Exorcist Regan MacNeil Animated Standing Prop
…seems to be no stopping it. In the face of the Devil, can faith prevail? We can't say for certain but we can faithfully report this is the most demonic animated Halloween prop ever. This Spirit Halloween exclusive The Exorcist Regan MacNeil Animated Standing Prop is a full five feet of non-stop…
Demon Vampire Adult Mens Costume
Torture your prey and have fun doing it in this Demon Vampire Adult Mens Costume. The knee length,Victorian cut black coat features long sleeves and silver double button front closure, complete with black dickie faux shirt front with a long burgundy neck tie and demon vampire mask with hair.
Fade In and Out Demon Child Costume
Freak everyone out when you wear the Fade In and Out Demon Child Costume. This spooky costume features an eye mechanism that allows red eyes to brighten and fade, complete with shirt, hood with mask, tunic, wrist ties, ankle ties, a belt and matching gloves.
Sexy Chucky Adult Womens Costume
You'll kill it this Halloween in the officially licensed Sexy Chucky Adult Women's Costume. Demonize children and adults alike in this blood-splattered overall skirt with tight fitting multicolored top and cherry red thigh highs, that draw attention to your killer looks.
Reel F/X™ Dark Lord Makeup Kit
Rise out of thunder and fog to scare all your friends and guests as the devil this Halloween by using this Reel F/X™ Dark Lord Makeup Kit. The kit includes pre-painted latex prosthetics and adhesives. Just add a black wig (sold separately) to complete the look. Now, emerge from the ninth circle of…
Red Devil Horns Appliance
A true devil needs the Red Devil Horns Appliance. These short red horns look so realistic people will think you are actually the evil demon. Be prepared for them to beg for forgiveness and cackle with no remorse.
Forsaken Soul Child Costume
Even your big brother will be scared of you in this Forsaken Soul Child Costume. In this black faux velor dress with lace up chest, draping sleeves and white spiritual haunted detail, you'll look wisely wicked.
Psycho Pig Mask
What would happen if a pig developed a taste for two legged meat - it would be very dangerous. Capture the danger when you create a demonic character of your own making with this Psycho Pig mask.


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clematis re-trellis
We have a four year old clematis that seems very happy where she is and she has out-grown the 4 foot high trellis. How do we get the clematis off the current trellis and get it going on a taller trellis?
Agreed, Gg48 gave good advice. Do you know the pruning type of your clematis? Some do best pruned hard every year. Some are pruned early spring to new growth on the old stems. Some are rarely pruned.
Also if you know the variety you can plan to have a trellis that will hold the entire upward growth or use a shorter trellis and plan for the upper growth to drape over. Some clematis grow twenty feet or more and some only a few feet. Many grow in the 8-10 feet range. I find it difficult to buy a pre-made trellis in my area that is much taller than six feet. And the trellises seem to be getting more narrow as well.
I have the same question about my Dr. Ruppel..which is in prunning group#2..The trellis is has been on has to be replaced. The man that usually does my prunning and Spring and Fall maintainence didn't get to the prunning until sometimes in April this year and Dr. Ruppel didn't bloom like it normally does. There is a lot of dead wood in back of clematis, where there was so blooms. Why can't I cut it back now and how far do i cut it back? Wouldn't it make sense to cut it back to about 6-12 in. like you do a group#3, feed it and hope it returns in the Spring? The existing trellis is wood and falling apart and I want to buy a wrought iron one to replace it.
Any suggestions?
I would wait until after a killing frost so that the plant doesn't go into winter with lots of new growth. In my zone that will be in the next few weeks. At that time you can cut it back to the 6-12inches. It will come back in the spring. I grow many P:2 clematis and most die back to near the ground and still come back and bloom in the spring and have some rebloom in the summer/fall.
One year I had to cut some of my P:2 clematis back before a killing frost and even with new growth they survived the winter and bloomed the next spring.
Thanks for the prunning information. Guess I better go down to Home Depot this week and buy the new trellis, while they still have the gardening stuff out. Will soon be filling up the space with holiday trees and decorations,etc.
Dwyerkg, I know there is one woman on the New England forum who lives right on the water on Cape Cod and has sweet autumn clematis, so I know that at least that type is OK with wind and salt air. If you don't get an answer here, you could ask to see if anyone else on the NEF grows clematis near the ocean.
Dwyerkg, you could contact Cindy at Hummingbird Farm in Maine. I believe that she is in USDA zone 5a, so she should be able to help with this question.
Cindy offers quite a few of the Kivistik clematis, which she says are hardy to zone 3, and she told me in an e-mail earlier this year that she hopes to offer more from this collection next year.
Here is a link that might be useful: Kivistik clematis at Hummingbird Farm
As far as hardiness to cold and wind, if you plant type 3 pruning (whack off everything down to a couple pairs of buds per stem once it gets cold every year) there won't be problem since there isn't enough plant to catch the wind. If I can grow them here on the border between zones 4 and 5 in a windy river valley, they won't have a problem for you, Dwyerkg. Hummingbird Farm is inland not on the coast, so I don't know if she has customers along the Maine coast, but I have been quite pleased with the clematis I have gotten from them.
The only concern I would have about growing clematis near the ocean would be salt spray. You would also need to be sure that your trellis is quite firmly planted so that it doesn't blow over in high winds.


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Album Rating: 4.5lol how does silent's pile of shit review get more comments than this in one day? album rules btw
Digging: Runaway Brother - Mother
Album Rating: 4.5I still think it did quite well with the number of ratings and comments.
Album Rating: 4.5it did..no doubts there.
Album Rating: 2.0Smoke Bomb is awesome, but this is just boring and rather irritating to listen to
Album Rating: 4.5Mind boggling that you don't like this, dude.
Album Rating: 4.5One might say it's puzzling
cant get into this album
Unpredictable album to say the least. Takes turns that I love, and some I hate.
Great overall though. Deluge is beast.
Album Rating: 4.5Deluge is my favorite track too. Ah. That chorus. Here's hilarious new promo explaining the 12 Project:
Album Rating: 4.5would be awesome if this slips into the users' list
Album Rating: 4.0Top 3 albums of the year for me
Album Rating: 2.0ehh
Digging: Andy Stott - We Stay Together
NINJA MANIA do you like collecting ninjas one ninja two ninjas three ninjas that's how fast it goes and it's all cgi there are more where those ninjas came from
Album Rating: 3.0guys this is really kind of uh...
Album Rating: 4.5aoty
Album Rating: 4.5Not quite. Deftones and The Siren Tower are just ahead.
Album Rating: 4.5Deftones have always bored the shit out of me, but I'll check out The Siren Tower
Album Rating: 4.5I only like the new albums of Hawk Eyes and Beardfish more than this.
Album Rating: 4.5The Siren Tower: http://www.youtube.com/watch?v=7r78LPCEk0Q
Album Rating: 4.5props for rec'ing the siren tower, this is amazing
Bands: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


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Current Courses
Previous Courses
The program aims to provide participants with a thorough grounding in the theory and practice of development planning and management practices in the mining sector within a range of international and national contexts. The course will be hosted by the School of Earth and Environment at The University of Western Australia.
The short course will provide you with an overview of the nature and management of occupational health and safety in the resources sector. You will have the opportunity to develop key leadership skills so that you can take a senior role in the oversight of occupational health and safety.
During this workshop you will be introduced to good practice in mineral tax collection procedures and processes. The topics include mineral royalties, corporate income tax, transfer pricing, tax administration, mining related tax issues, and institutional and administrative capacity issues.


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(Mar. 30-May 30)
Oympiakids.com or call 826-4296
Looking for a cheer team-we have a spot for you.
Cheer Clinic April 13-May 1 / Cheer Team Tryouts May 2
Call Register Online or call 826-4296 for all the info
Summer Camp-Register Online...Spots will fill QUICKLY!
Same PRICE as Last Year-5 MORE hours of camp per week!
Click Class Schedules on this page and then select Camps.
NEXT PARENTS' NIGHT OUT... SATURDAY, March 25 6:30-10:00PM
Take a break while your kiddos have a BLAST! Ages 4 and Up.
$20 per child. Pizza, Drinks, Open Gym & Games. Open to the public! Call 826-4296 to register.


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- 1 week ago by Jill O'Rourke
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As Ellie explains to Ellen, even though she's a very funny, lovable human, sometimes people don't recognize her. Like on the subway. Or even at award shows. More
As Ellie explains to Ellen, even though she's a very funny, lovable human, sometimes people don't recognize her. Like on the subway. Or even at award shows. More
One of the many reasons I don't envy celebrities is the constant pestering they get about having kids. If they don't have kids, they're asked when they're going to have them. If they do have kids, they're asked when they're going to have more of them. If they don't want kids, they're asked why, or they're encouraged to change their minds. More
How are you feeling today? A little down? A little confused? Were you looking for something to restore your faith in the universe? How about listening to Mindy Kaling explain her reasons for not liking one night stands? That always cheers me up! More
Amy Poehler and Bill Hader stopped by The Ellen DeGeneres Show yesterday to premiere the new trailer for their upcoming Disney Pixar movie Inside Out. So I'm holding them responsible for my tears. Thankfully they made up for giving me all the feels by giving me all the giggles. More
I think what makes Cate such a joy to watch is that she's this radiant, stylish, well-spoken woman who plays a lot of very serious, powerful roles, but she can turn on the silliness at the drop of a hat. More
Guys, I hate to say this, but I think Ellen DeGeneres just jumped the shark. More
Apparently once a week wasn't often enough for Justin Bieber to appear The Ellen DeGeneres Show, because he's on again today. That's the second time this week. More
Kristen's hubby Dax Shepard was on Ellen's show last month, and he made the birth experience sound nightmarish. That's because he witnessed Kristen's C-section, which was not pretty. From Kristen's end, however, it was great. She actually says she "really enjoyed" it. Perhaps a little too much, based on her hilarious explanation of how it all went down. More
Justin Bieber is on The Ellen DeGeneres Show today. I know what you're thinking, because I'm thinking it too: AGAIN? Yes, apparently when Justin and Ellen agreed that he should come on the show every week, they weren't joking. More
Is it too late for me to become Connie Britton when I grow up? To have fabulous hair and star on several hit TV shows and tell charming stories about meeting the president? More
Just in case you're keeping track, he's now done one Ellen appearance saying he's nervous about what people think of him, one Facebook video explaining said Ellen appearance, and now one Ellen appearance explaining said video. More
I don't know if this is making me want to have a baby of my own or just be Mila Kunis' baby. It's a confusing time for me, but I'm working through it. More
One of Ellen's favorite pastimes is scaring the poop out of celebrities, so obviously she had to try it on Jimmy when he visited her show. But here's the thing. Jimmy's a talk show wizard too, so he knows all the tricks. More
If you're assuming I'm rolling my eyes right now, your assumption is correct. More


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Effects of infection and disease with Mycobacterium tuberculosis on serum antibody to glucan and arabinomannan: two surface polysaccharides of this pathogen
1 Departments of Molecular Virology & Microbiology and Medicine, Baylor College of Medicine, Houston, TX, USA
2 Program on Developmental and Molecular Immunity, Eunice Schriver Kennedy Institute of Child Health and Human Development, NIH, Bethesda, MD 20852, USA
3 Ben Taub General Hospital, Houston, TX, USA
4 CBER, Food and Drug Administration, Houston, TX, USA
BMC Infectious Diseases 2013, 13:276 doi:10.1186/1471-2334-13-276Published: 19 June 2013
The role of the surface capsular polysaccharides (CPs) of Mycobacterium tuberculosis (Mtb) in the pathogenesis of infection and disease, as well their potential for use as diagnostic reagents and vaccine antigens, are unknown.
Serum antibody to two CPs of Mtb, arabinomannan (AM) and glucan (Glu), were studied in samples from 52 18–74 year-old HIV-seronegative, immunocompetent individuals in Houston Texas. The effects of Mtb exposure, infection and disease upon the levels of antibodies to these CPs were assessed. Subjects were grouped according to the standard international classification.
IgA anti-Glu levels were significantly higher in the active and treated TB compared to a group that was PPD-negative without TB exposure history (p<0.05). Antibodies against AM demonstrated a similar pattern, with the exception that IgG anti-AM was higher in groups who had active TB or previously documented active TB, and IgA anti-AM was higher in subjects with previously documented active TB compared to the level in an unexposed, PPD-negative group (p<0.05). Serum IgG anti-Glu levels were higher in subjects with active TB or previously documented active TB than in the unexposed PPD-negative group, but the differences were not significant.
These data suggest that the evaluation of antibody responses to the CP of Mtb may have utility for TB serodiagnosis, and that vaccines designed to induce humoral responses to TB CPs should be tested for their capacity to evoke anti-tuberculosis protective immunity.


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This weekend's 73rd Members Meeting held at Goodwood saw another spectacular visual feast for anyone with a passion for period motor racing. I took the opportunity to catch up with friends old & new over a freezing cold, but very entertaining couple of days. If you are not familiar with the event it is a pretty unique. It […]Continue Reading —›
It was great to be asked by photography magazine 'In My Bag' to share the details of the camera kit, rigs, lighting and accessories that I use for my work and some advice for budding photographers – here are a few excerpts below. To read the full article click here. To read the full article […]Continue Reading —›
The 12th Shanghai International Photographic Art Festival & Exhibition took place recently, and I was pleased to be one of two UK photographers selected from the Association of Photographers London to take part along with the very talented underwater & dance photographer Maya Almeida – http://www.mayaalmeida.com/ Here are a few images from the Festival, Exhibition and […]Continue Reading —›
Last week was the Private View of the Squint Showcase Exhibition hosted by The Red Brick Road London. Thanks to all who made it happen and for all of your hard work – Janet, Karen, Phil & co. Here are a few images from the evening… The image which we chose to exhibit is running currently […]Continue Reading —›


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|Live Scores
|Video & Audio
New Zealand
|Showing 1-20
Plunket Shield 2014-15, 4th day
Andrew Ellis extends Canterbury dominance
Mar 20, 2015: A round-up of the Plunkett Shield matches that ended on March 20, 2015
Otago v Wellington, Plunket Shield 2014-15
Otago take five points from draw
Mar 3, 2015: Michael Papps registered his 26th first-class century on the last day of Wellington's draw in their Plunket Shield game against Otago
Plunket Shield 2013-14
De Grandhomme steers Auckland to six-wicket win
Dec 23, 2013: A round-up of the Plunket Shield matches that ended on December 23, 2013
West Indies in New Zealand 2013-14
New Zealand batsmen build home advantage
Dec 15, 2013: The home is where the heart is, and it's also where the runs have been for New Zealand this year
Plunket Shield 2013-14
Canterbury hold nerve for 10-run win
Dec 7, 2013: Round-up of all matches in the Plunket Shield that finished on December 7, 2013
Auckland v Wellington, HRV Cup, Auckland
Wellington prevail in high-scoring contest
Nov 30, 2013: Wellington outclassed Auckland in a high-scoring HRV Cup match in Auckland during which a record 27 sixes were hit
Wellington v Auckland, HRV Cup, Wellington
Wright, Cachopa give Auckland thrilling win
Nov 23, 2013: Luke Wright and Craig Cachopa gave Auckland a victory in their first match of the HRV Cup, against Wellington
Ford Trophy 2012-13
Wellington just short in huge chase
Mar 9, 2013: After Jamie How struck 222 on Wednesday, the Ford Trophy was treated to another high-scoring match when Auckland, after posting 383 in Eden Park, beat Wellington by 18 runs
Ford Trophy 2012-13
How scores double as records tumble in Hamilton
Mar 6, 2013: A round-up of the Ford Trophy matches on March 6
The Ford Trophy, 2012-13
Southee, Williamson shine for Northern Districts
Feb 28, 2013: Tim Southee and Kane Williamson starred in Northern Districts' win over Auckland, while Central Districts beat Wellington and Canterbury crushed Otago in the Ford Trophy matches
Plunket Shield 2011-12, 4th round
Arnel, Vettori star in Northern Districts win
Feb 27, 2012: Northern Districts fought back to beat Canterbury at the Mainpower Oval in Rangiora, winning their third game of the tournament and taking the lead in the points table
Ford Trophy 2011-12, 7th match day
Otago sneak home in high-scorer
Jan 29, 2012: A round-up of the Ford Trophy matches that took place on January 29
New Zealand news
Jul 7, 2011: Canterbury's Michael Papps has quit the province after 12 seasons there and will play for Wellington in the 2011-12 New Zealand domestic season
Plunket Shield, 10th round, 4th day
Northern Districts beat Central Districts to win Plunket Shield
Apr 1, 2010: A round-up of the tenth round of matches in the Plunket Shield
Plunket Shield, 8th round, 4th day
Central Districts, Canterbury post wins
Mar 15, 2010:
New Zealand Cricket one-day competition 2009-10, 8th round
Canterbury steal tie with late burst
Feb 6, 2010: A round-up of the action from round eight of the 2009-10 New Zealand Cricket one-day competition
Plunket Shield 2009-10, 5th round
Dec 15, 2009: A review of the fifth round of games in the 2009-10 Plunket Shield
New Zealand Cricket one-day competition, 1st round
Central Districts win despite Papps' 150
Dec 8, 2009: A summary of the first round of matches in New Zealand's domestic one-day competition
Canterbury batsman stood ground after dismissal
Papps fined for dissent in Auckland
Mar 26, 2008: Michael Papps has been fined half his match fee after being found guilty of dissent during Canterbury's State Championship match on Monday
Canterbury v England XI, 2nd tour match, Christchurch
Feb 3, 2008: Alastair Cook struck gold in the second practice match against Canterbury, blasting an unbeaten 138 off 140 balls, etched with 20 hits to the boundary and two beyond it, to take the England XI to a convincing seven-wicket win in Christchurch
|Showing 1-20
Wet weather dulls India's threat perception
The SCG might be India's preferred semi-final venue at this World Cup, but persistent rain in the lead-up has left them worried their spinners may not get the help they are widely expected to
From 110 to 150 kph, the Wahab Riaz story
As a six-year-old, he watched Wasim Akram at the 1992 World Cup and decided that he would be a left-arm fast bowler. As a man, he put on a show very nearly as memorable as Wasim's 23 years before
This contest brings together a belligerent bunch of brats and braggers from two countries that are so different, yet share rampant egotism and a high opinion of themselves
Dhoni masters numbers game to crack ODI code
Over the last few months, he has slowly moved from a flashy finisher, to a more measured risk manager
Time slips by South Africa once again
It was Grant Elliott and New Zealand's time in Auckland. Not South Africa's. But the Proteas will leave this tournament wondering when that will ever change. Maybe next time.
The battle of the bullies (236)
This contest brings together a belligerent bunch of brats and braggers from two countries that are so different, yet share rampant egotism and a high opinion of themselves
India swept away by Australia's depth (183)
India's Plan A in this World Cup had worked flawlessly over seven matches. When they came up against the toughest opponents in the World Cup, however, they were left scrambling for a back-up plan
Time slips by South Africa once again (147)
It was Grant Elliott and New Zealand's time in Auckland. Not South Africa's. But the Proteas will leave this tournament wondering when that will ever change. Maybe next time.
Wet weather dulls India's threat perception (140)
The SCG might be India's preferred semi-final venue at this World Cup, but persistent rain in the lead-up has left them worried their spinners may not get the help they are widely expected to
The greatest time of our lives (138)
Whatever happens, the Australia-New Zealand World Cup final at the MCG will be the most divine fun


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Mac And Aids
Here's a taste of what TheBody.com has to offer on this topic:
Ask the Experts
mac without aidsMy father died of mac a year ago. He did not have aids. How could he have gotten it and how common is it for a non-aids patients to get mac.
Response from Judith Feinberg, M.D.
University of Cincinnati, College of Medicine...HIV-s can get MAC although that does not happen often. The germ is in soil and water throughout the environment, so it is not hard Read more »
My partner has reactivated to CMV and possibly MAC due to his AIDS treatmentMy partner of 4 years was just diagnosis with AIDS one month ago. His viral load is 735K and his... Read more »
Death (HIV/AIDS A CHRONIC, NOT ALWAYS SO MANAGEABLE, CONDITION, 2010) ( HIV AND ACCELERATED AGING, 2010)I think the p.c. word is morbidity . I recently had an argument with one of the very few friends iv... Read more »
MAC AIDS Fund Promises More Grants for Anti-AIDS Efforts in Chinese Mainland, Hong Kong...fund's executive director. In addition to outreach, the fund will support efforts to promote AIDS awareness, community-level HIV testing, and basic HIV treatment. Targeted condom promotions and other community-focused education and support to... Read more »
MAC AIDS Fund Survey of People in Nine Countries Finds Misconceptions, Stigma...India, Mexico, Russia, South Africa, the United Kingdom and the U.S. found misconceptions about the availability of a cure for HIV/AIDS and the consequences of the disease, as well as signs of stigma against HIV-positive people, Reuters Health ... Read more »
Fergie's Lip Service Serves Charity Well; MAC's AIDS Campaign to Benefit... The cosmetics company MAC has named singer Fergie, of the group Glamorous, as the newest spokesperson for its Viva Glam HIV/AIDS campaign. Fergie joins Dita Von Teese and Eve, who are already spokespersons for the effort. Fergie said she looks... Read more »
The Role of Public Private Partnerships in the National HIV/AIDS Strategy...blog. James Albino is the Senior Program Manager in the Office of National AIDS Policy. Today, the White Office of National HIV/AIDS Policy (ONAP) engaged the business community, private foundations, and the HIV/AIDS community to begin a... Read more »
Connect With Others
Long-term HIV and Aids survivors' health worrying
Posted by ScotCharles...From KaiserNet January 8, 2008 Some experts and doctors recently have voiced concerns that people who were diagnosed with HIV and Aids in the early years of the epidemic are experiencing "premature[e]" or "disproportionate numbers" of ailments... Read more »
Hiv and AIDs reporting
Posted by rain05, 5 RepliesWhat exactly does the CDC do with your name and information? Who is able to access it? Read more »
Workplace issues and HIV/AIDS
Posted by ScotCharles...http://www.thebody.com/workplace.html Check out this link for workplace issues with HIV/AIDS. It is very thorough. Read more »
HIV/AIDS Blogging/Blogs
Posted by DaveyBoy, 2 Replies...Blog is online (web based) journal or small blurbs people can read or comment. My HIV/AIDS blog is on http://hiv-aids.blog-city.com Other POZ blogz on http://www.HIVforum.com/blogs/ Read more »
Resource Centers
Guides for People With HIV


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David Randall, author of the book Dreamland: Adventures in the Strange Science of Sleep, MIT neuroscientist Matt Wilson, PhD, and Harvard instructor of psychiatry Erin Wamsley, PhD, discuss the science of sleep and dreams. Wilson and Wamsley were panelists at an event held at the Academy, hosted by Science and the City in collaboration with the 5th Annual Imagine Science Film Festival, titled The Strange Science of Sleep and Dreams.
Leading scientists discuss the latest breakthroughs in lysosome biology and what they mean for treating Batten disease, and more common conditions such as Alzheimer's and Parkinson's diseases and cancer.
In the second of a two-part series, experts look at the links between health and nutrition. They examine everything from how nutrition impacts hospital stays, to cancer and aging, to developing food science innovations, and improving diet.
In this first of a two-part series, experts from various sectors explore the available options to reduce "hidden hunger"—micronutrient deficiencies in a population.
The New York Academy of Sciences is the world's nexus of scientific innovation in the service of humanity. For nearly 200 years — since 1817 — the Academy has brought together extraordinary people working at the frontiers of discovery and promoted vital links between science and society.
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- Top of page
- Abstract
- Introduction
- Antimicrobial peptides and proteins are principal effector molecules of innate mucosal host defense
- Human cervicovaginal fluid contains a number of anti-HIV-1 peptides and proteins
- Hormonal regulation of antimicrobial peptides and other mediators of vaginal innate immunity
- Bacterial vaginosis causes dysfunction in innate immunity of the vaginal mucosa
- Retrocyclin, an ancestral human θ-defensin, can potently prevent HIV-1 infection
- Acknowledgments
- References
Mucosal surfaces of the cervix and vagina are portals for heterosexual transmission of human immunodeficiency virus type 1 (HIV-1) and, therefore, play a fundamental role in the pathogenesis of primary infection. Cationic antimicrobial polypeptides including defensins are the principal effector molecules of mucosal innate immunity against microbes and viruses such as HIV. In cervicovaginal secretions, antimicrobial polypeptides constitute the majority of the intrinsic anti-HIV-1 activity, synergism between cationic polypeptides is complex, and full anti-HIV-1 activity involves the complete complement of cationic polypeptides. Periods in which cationic antimicrobial polypeptide expression is reduced are likely associated with increased susceptibility to HIV-1 infection. This review provides an overview of the role of cationic antimicrobial polypeptides in innate cervicovaginal anti-HIV-1 host defense, and discusses how hormones and bacterial infections can regulate their expression. Emphasis is placed on the θ-defensin (retrocyclin) class of anti-HIV-1 peptides and their potential for development as topical microbicides to prevent HIV-1 transmission.


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Check out the new, mobile-friendly WineSpectator.com!
First << 45678910 >> Last (208)
A Wisconsin study found regular wine drinkers experienced lower rates of visual impairment
Posted: June 30, 2014 By Esther Mobley
Barolo, Barbaresco, Nizza Monferrato and Barbera among areas cited by U.N.
Posted: June 27, 2014 By Bruce Sanderson
Incidence of bottle rupture rises to 13; devices need not be returned, but Coravin-issued neoprene sleeve required for safe use
Posted: June 26, 2014 By Esther Mobley
Leading producer of value Pinot Noir and Chardonnay earns certification as a benefits corporation
Posted: June 18, 2014 By Dana Nigro
The popular ratings app provides access to 300,000 wine reviews on multiple devices
Posted: June 16, 2014
Big name wineries largely spared, but many small growers will have a tiny crop this vintage
Posted: June 13, 2014 By Suzanne Mustacich
Former owner of Cru plans to auction trove of 100,000 bottles, most of it Burgundy
Posted: June 11, 2014 By Mitch Frank
Pharmaceuticals billionaire buys winery and vineyard; Mondavi looking for new home
Posted: June 10, 2014 By MaryAnn Worobiec
Nation's highest-earning charity wine auction raises a record-breaking sum for a second straight year
Posted: June 9, 2014 By MaryAnn Worobiec
Environmentalists who fought vineyard plans see it as affirmation; winery says it's focusing on Napa
Posted: June 6, 2014 By Kasey Carpenter
Charging yeast with magnetic nanoparticles could speed disgorgement, but winemakers aren't so sure
Posted: June 5, 2014 By Esther Mobley
Gadget extracts wine without opening bottles, but damaged bottles ruptured during use
Posted: June 3, 2014 By Esther Mobley
Plus, red wine might be good for your teeth, and binge drinking is never a good idea
Posted: June 2, 2014 By Esther Mobley
Winemaker Chris Mazepink hires prominent Willamette Valley names for Pinot Noir producer
Posted: May 30, 2014 By Katherine Cole
Convicted fraudster asks judge for leniency; Judge asks prosecution for more information
Posted: May 29, 2014 By Peter Hellman
Winemaker Jamey Whetstone gains financial backing and will take post at Evening Land's Sonoma winery
Posted: May 28, 2014 By Aaron Romano, Mitch Frank
A first look at vintage quality down south, with eyewitness reports from growers and winemakers
Posted: May 23, 2014 By James Molesworth
Investigation finds fungicides used improperly during windy day; locals debate safety of chemicals
Posted: May 23, 2014 By Suzanne Mustacich
A first look at vintage quality down south, with eyewitness reports from growers and winemakers
Posted: May 22, 2014 By Kim Marcus
A first look at vintage quality Down Under, with eyewitness reports from growers and winemakers
Posted: May 21, 2014 By Augustus Weed, Aaron Romano
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It's so cold that rain turns to snow. Spit crackles before it hits the ground. And the wind can freeze exposed skin in less than a minute.What the heck are you doing outside? You're riding! You're outside enjoying the wonders of this planet and you didn't stop just because the weatherman said you should. The Baltic Balaclava was made just for you.
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If there's a thread on this allready I could'nt find it but anyhoo here goes .Just wondering what's everyone preferance of which grain they prefer ? 180,165,155, or 135 and why ?
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i use 180gr for target, defense ammo is 165gr hp. the 180 seem to come out of my xd fairly well
For Defense and Tactical:
Buffalo Bore: 40 Heavy ACP +P 180 grain 1100/484 JHP #23B/20
Corbon: 40 165 grain Self-Defense 1150/485 JHP #SD40165-20
Hornady: 40 S&W 165 grain FTX 1175/506 JHP #91340
Winchester: Supreme Elite 40 S&W 180 grain PDX1 1010/408 JHP #USA40JHP
Remington: 40 S&W ACP 165 grain 1150/485 fps MC #LN40SW4
For Range and Plinking:
American-Eagle: 40 S&W 155 grain FMJ 1140/445 #AE40R2
Tul Ammo: .40 S&W FMJ 180 GR 990 fps #TA401800
175 gr hard cast truncated cone for target use. 180 gr Gold Dot for carry
In life, strive to take the high road....It offers a better field of fire.
"Robo is right" Fuzzball
I use 180 white box Winchester for range and plinking .Currently 180 Winchester Rangers for SD . I bought a box of Winchester Supreme Elite 165 gr for SD yesterday .I've always shot 180 in my .40 and have lil experiance with a lighter grain .I was just wondering about the pro's n con's about differant grains if any ? I know smaller the grain the higher the velocity and I need to get to the range and find out for myself .
The lighter the bullet, the lower the sectional density. Lower SD's lead to less penetration (generally).
If you want the balance of velocity and accuracy, look to 155-165gn bullets.
180gn is the maximum bullet weight recommended by most loading manuals
135gn is for high velocity, fast expanding bullets usually used for self-defense. Handloading can be a problem since the bullet is not seated very deep in the case and may cause bullet set-back
I find that 145-155gn bullets are the most accurate


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- Description
DetailsGelish Need A Tan Gel Nail Polish
The tone is tan. The brand is Gelish. The polish is Gelish Need A Tan gel nail polish from OneSourceBeauty.com. This skin tone shade looks great against any complexion.
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Listed in...Cafe | Days Out | Out and about | Sculpture | Walks | Food and Drink | Culture
An internationally recognised centre for contemporary art, The Yorkshire Sculpture Park is handily situated just off the M1 near Wakefield. Readily accessible from Leeds….. and well worth it! Set up in 1977 as a designated sculpture park in the grounds of an old country house, the YSP holds some of the UK's best sculptures, all of which are outside. henry Moore, andt Goldsworthy, Anthony Caro, along with many other leading sculptors, all have works on permanent exhibition. The indoor galleries and space outside act as ideal locations for the ever changing displays of other contemporary artists. The beautiful parkland provides the perfect backdrop in which to see these magnificent works of art. Also there are two cafes which serve a range of home-cooked snacks and meals, all to a very high standard. All in all, this makes for a perfect day out! Allow yourself a good few hours for the visit as there's so much to see.
Listed in...Cafe | Days Out | Out and about | Sculpture | Walks | Food and Drink | Culture
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Downright Cosy Pubs To Get You Through The Colder Months
Cold weather means one thing – time to cosy up in one of these Leeds pubs...
21 Things You Probably Don't Know About Leeds
How many of these little known facts about Leeds do you know?
The Most Unusual Leeds Restaurants
Fancy something different? Try these rather unusual restaurants in Leeds...
Leeds Burgers: Tried and Tested
Our reviewers tried and tested some of the best burgers in Leeds...


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Mela Artisans Island Dreams Pillow
Mela Artisans Island Dreams Pillow
Weights & Dimensions
|Product Type: Throw pillow
|Style: Contemporary
|Size: Medium (16" - 20")
|Shape: Square
|Cover Material: Silk
|Fill Material: Other
|Number of Items Included: 1
|Embroidered: No
|Pattern: Geometric
|Organic: Yes
|Gender: Unisex
|Life Stage: Adult
|Tassels Included: No
|Piped Edges: Yes
|Contrasting Border: Yes
|Removable Cover: Yes
|Reversible: Yes
|Washing Method: Dry clean only
|Eco-Friendly: Yes
|Country of Manufacture: Imported
Still have questions about this product? We're here to help
Mela Artisans Island Dreams Pillow
About the ManufacturerMela Artisans is a luxury lifestyle brand that combines traditional handcrafting techniques with the freshness and functionality of contemporary design. Their distinctive and original collections fuse modern designs with enduring techniques passed down through generations in artisan communities. Their vision is to provide a sustainable global market for artisans while fostering entrepreneurship within their communities. Through their innovative luxury brand, you can enrich your life with beautiful and functional handcrafted artwork while being inspired by the stories of the artisans who created them. At the same time you can forge a personal connection with these same artisans through purchases and loans that allow them to grow their businesses and develop their artistic skills. Join them as they reach across the globe to form a new community committed to the preservation of handcrafted artisan traditions.
Tell us what you think!
Tell us what you think about this product. It will help us provide you with better products in the future and help your fellow shoppers make better purchases.Write the first review
OUR SKU # MART1227Island Dreams Pillow is also sometimes listed under the following manufacturer numbers: MAPL047, MAPL048, MAPL049, MAPL050


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Welcome to the
Penndel-Hulmeville Memorial Day Parade
Memorial Day is the day we as a nation, as Americans set aside to salute the brave soldiers who have given the ultimate sacrafice in service of this great land. Through the years, we may have forgotten the meaning behind Memorial Day. Some think of it as the beginning of summer, and others look for a good sale; yet there are handful of people who still fly the American Flag and say a prayer for the service men and women who gave their lives for our freedom. Our committee is dedicated to that mission.
We are a an Official Commemrative Partner in remembering the 50 year anniversary of the Vietnam War, recoginized by the US Dept of Defence.
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Do you like what we do and want to do what you can to help? Read more about us.


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Hotel Schwarzwaldhotel & Restaurant Stollen - Gutach
Elzacher Straße 2 - Gutach1-877-662-6988
Welcome to Schwarzwaldhotel & Restaurant Stollen!
Your 3 star Gutach im Breisgau hotel has its own restaurant serving dinner. There is also a bar/lounge where guests can enjoy drinks after a long day. Multilingual staff can provide tour/ticket assistance, express check-in and express check-out.
Free Wi-Fi is available. Enjoy free newspapers in the lobby, where you will also find a safe at reception for your valuables.
These reviews have been left by customers who actually stayed at this hotel
Check Availability at Hotel Schwarzwaldhotel & Restaurant Stollen
Breakfast at Hotel Schwarzwaldhotel & Restaurant Stollen
A free buffet breakfast is available between 8:00 AM and 10:00 AM.
Hotel Facilities at Schwarzwaldhotel & Restaurant Stollen
- Bar
- Restaurant/Dining
- Dogs allowed
- Room service - limited hour
- Pets accepted
- Meeting Room
- Multilingual staff
- Newspapers
- Front desk - safety deposit box
- City tour
- Internet/Email services
- Free parking
Know before you go
Check-in: between 2:00 PM and 10 PM.
Check-out: before noon.
PolicyExtra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
City tax and/or any other fees charged by the hotel
You'll be asked to pay the following charges at the hotel:
- A tax is imposed by the city: EUR 1.60 per person, per night. This tax does not apply to children under 16 years of age.
We have included all charges provided to us by the property. However, charges can vary, for example, based on length of stay or the room you book.
Renovation and closuresThe following facilities are closed seasonally each year. They will be closed from 25 October to 18 November:
- Dining venue
Schwarzwaldhotel & Restaurant Stollen Hotel reviews
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- May 2011
- Venere Guest
- Family with older children
- Italy
- September 2012
- Venere Guest
- Family with young children
- France
- November 2014
- Venere Guest
- Not Specified
- Germany
Schwarzwaldhotel & Restaurant Stollen Hotel reviews by TripAdvisor
Room Details
Book your pet-friendly accommodation at the 10-room Schwarzwaldhotel & Restaurant Stollen. Rooms open onto balconies. Televisions in each room offer entertainment at the end of a long day. Business travelers will have access to free wireless high-speed Internet access as well as desks and phones during their Gutach im Breisgau visit.
Every room comes with an ensuite bathroom. Minibars and hair dryers are supplied in each room to facilitate basic travel needs. Additional comforts include soundproofing.
Accommodation Services
- Telephone
- Mini bar
- Soundproof rooms
- Hairdryer in each room
- Desk
- Wireless Internet access
- Terrace/Balcony
Distances from Hotel Schwarzwaldhotel & Restaurant StollenMesse Freiburg - 16.4 km / 10.2 mi
Schlossberg - 17.6 km / 10.9 mi
Muensterplatz - 17.7 km / 11 mi
Freiburg Main Cathedral - 17.7 km / 11 mi
Old Town Hall - 17.7 km / 11 mi
New Town Hall - 17.8 km / 11 mi
Schwabentor Gate - 17.8 km / 11.1 mi
Martinstor Gate - 18 km / 11.2 mi
Freiburg Theater - 18 km / 11.2 mi
Breisacher Gate - 18.1 km / 11.3 mi
University of Freiburg - 18.1 km / 11.3 mi
Freiburg Concert Hall - 18.1 km / 11.3 mi
Goethe Institute - 18.2 km / 11.3 mi
Badeparadies Schwarzwald - 26.9 km / 16.7 mi
Feldberg Ski Resort - 27.8 km / 17.3 mi
The preferred airport for Schwarzwaldhotel & Restaurant Stollen is Basel (BSL-EuroAirport) - 67.6 km / 42 mi.
Distances are calculated in a straight line from the property's location to the point of interest or airport and may not reflect actual travel distance.
Distances are displayed to the nearest 0.1 mile and kilometer.
Transportation services Hotel Schwarzwaldhotel & Restaurant Stollen
- Free parking


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ICSC: Spring Chills Retail Sales Momentum
Tuesday April 9th, 2013 - 11:17AM
These are shortcuts to your favorite social networking and bookmark sites. Add this story to your Facebook page, del.icio.us, DiggIt, and many others!
The spring chill cooled retailer results for the week ended April 6, according to the International Council of Shopping Centers and the Goldman Sachs Weekly Chain Store Sales Index. In the period, weekly retail sales rose a slight 0.7%, although, in a warmer note, sales versus the 2012 period gained 2.1%.
"Abnormally cold weather throughout the fiscal month of March for much of the country curbed the consumers' appetite for spring apparel," said Michael Niemira, ICSC vp/research and chief economist. "Sales for the current week were affected by those colder-than-normal temperatures as well, but the seasonally-adjusted pace of sales improved by 0.7% from the prior week or rose by 2.1% on a year-over-year basis for the week ending April 6, 2013, the end of the fiscal month for many retailers," Niemira added.
For the month of March, ICSC said its expects sales will increase by between 2% and 3% in total, and between 4% and 5% less drug stores. March should garner a one or two percentage point advantage due to the earlier Easter holiday in 2013 versus 2012, the organization noted.
Tags: • Housewares • Cookware & Bakeware • Vacuum Cleaners/Electric Cleaning • Health & Personal Care • Home Décor • Home Environment • Small Electrics • Organization & Cleaning • Tabletop • Gadgets & Kitchen Tools • Retail •
Helen Of Troy Acquires Vicks VapoSteam Business From Procter & Gamble »
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Bloomingdale's To Open Norwalk, CT Store
Keurig's Kelley Named To Save The Children Board
BEA: Personal Income Gains But Expenditures Don't Keep Pace
Best Buy Canada Eliminates Future Shop, Boosts Multi-Channel Efforts
Belk Comps Advance, Investments Hit Bottom Line
Keurig, Reily Foods Sign Manufacturing, Distribution Agreement
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Gauging trends remains an inexact science despite all the analytics and insights available to help vendors and retailers decide what's hot and what's not.