Objective(s): Denaturing high performance liquid chromatography (DHPLC) is a high throughput approach for screening DNA sequence variations. To assess oven calibration, cartridge performance, buffer composition and stability, the WAVE Low and High Range Mutation Standards are employed to ensure reproducibility and accuracy of the chromatographic analysis. The purpose of this study was to provide a cost-effective homemade mutation standard for DHPLC analysis. Materials and Methods: DHPLC was performed to evaluate different elution temperatures of a 374 bp DNA fragment with C>A mutation at position of 59 to achieve a peak profile similar to the Low Mutation Standard. In order to verify the reproducibility of the homemade mutation standard using DHPLC, 15 different experiments were performed to compare the homemade mutation standard, the WAVE Low Range Mutation Standard with a positive DNA control sample. Results: We identified a comparable elution temperature and a peak profile with the WAVE Low Range Mutation Standard. Conclusion: This study confirmed the reproducibility of the peak profile of our homemade mutation standard compared to the Low Mutation Standard using DHPLC analysis.


Vans Pro Skate Park Series (VPS) and the International Skateboarding Federation (ISF) today announced a strategic partnership in advance of the new world championship skateboarding point series' inaugural qualifying event in Melbourne, Australia this Saturday, April 16 at St. Kilda Skatepark. VPS will partner with the ISF as the official sanctioning body for the 2016 Vans Pro Skate Park Series World Championships.


With excellent time-frequency local and multiresolution analysis characteristic, wavelet transform is widely used in signal and image processing. A new class of biorthogonal wavelet filter banks, named anti-symmetric biorthogonal wavelet filter banks with the same even length, was constructed in this paper. The paper deduced design formulas and then described design steps detailedly. Furthermore, properties of this class of wavelet were studied, and particularly differential operator property was analyzed in detail. As an example, this paper gave filter coefficients of the anti-symmetric Bior5.5 and drew their graphs of dual wavelet functions, which proved these properties of this class of wavelet correctly.


In order to study damage evolvement of SFRC concrete materials,strength distribution was studied using WEIBULL probability distribution function.By using relationship between damage and strength,formula of damage evolvement was presented out.Then linear regression method was used to calculate parameters in formula of damage evolvement.At last,formula of damage evolvement of concrete and two SFRC were given out using experiment data.Comparing the results,according to the same damage,the compressive strength of SFRC with 1% volume content is 14.7% higher than that of concrete.For SFRC with 3% volume content,the strength needed is 40% higher.


Based on the generalized nonlinear Schrdinger equation,the propagation characteristics of a super Gaussian femtosecond pulse in photonic crystal fibers were numerically simulated by split-step Fourier method.The result shows that soliton disintegration occured in shorter distances and soliton self-frequency shift was more remarkable for super Gaussian pulse than for Gaussian pulse,and a new lower power soliton appeared on the left side of the strong soliton.Otherwise,the 3rd-dispersion would lead to the dissymmetry and the complex structure for the pulse shape and its spectrum,and that would lead to the trend to form soliton.The pulse shape was smoothed by intrapulse stimulated Raman scattering.At the same time the energy between the two solitons was redistributed by self-steeping.


The anomalous dispersion signal of the bromine-containing kinase inhibitor H-89 was used to characterize discrete binding modes of the compound when complexed with the catalytic subunit of protein kinase A.


The next-to-minimal supersymmetric model with a light doubletlike CP-odd Higgs boson and small tan{beta} can satisfy all experimental limits on Higgs bosons even with light superpartners. In these scenarios, the two lightest CP-even Higgs bosons, h{sub 1} and h{sub 2}, and the charged Higgs boson, h{sup +}, can all be light enough to be produced at CERN LEP and yet have decays that have not been looked for or are poorly constrained by existing collider experiments. The channel h{sub 1}{yields}a{sub 1}a{sub 1} with a{sub 1}{yields}{tau}{sup +}{tau}{sup -} or 2j is still awaiting LEP constraints for m{sub h{sub 1}}>86 or 82 GeV, respectively. LEP data may also contain e{sup +}e{sup -}{yields}h{sub 2}a{sub 1} events where h{sub 2}{yields}Za{sub 1} is the dominant decay, a channel that was never examined. Decays of the charged Higgs bosons are often dominated by H{sup {+-}}{yields}W{sup {+-}}{sup (}*{sup )}a{sub 1} with a{sub 1}{yields}gg, cc, and {tau}{sup +}{tau}{sup -}. This is a channel that has so far been ignored in the search for t{yields}h{sup +}b decays at the Tevatron. A specialized analysis might reveal a signal. The light a{sub 1} might be within the reach of B factories via {upsilon}{yields}{gamma}a{sub 1} decays. We study typical mass ranges and more » branching ratios of Higgs bosons in this scenario and compare these scenarios where the a{sub 1} has a large doublet component to the more general scenarios with arbitrary singlet component for the a{sub 1}. « less


The article asserts that the efficiency of a collective action depends on two factors. First, the variation of the congestion cost according to the size and the membership structure defines equilibrium access conditions. Second, individual calculus and optimum perception are influenced by the individual's ability to regard others as partners. So, we use a model of discriminatory club with "moral ability\" to co-operate. Finally, some unusual club's shapes are described.


Abstract In recent years, machine vision systems have been introduced into the electronics manufacturing industry for control and inspection applications. For some applications, great benefit has been derived, but serious limitations affecting flexibility and the system life cycle have been exposed. This paper proposes a model for building integratable vision machines capable of deriving benefit from support information, providing facilities to ease change and improve flexibilily. A proof of concept implementation is discussed using information storage based on both the relational and the object-oriented models. The paper presupposes the need for an integration infrastructure such as that specified by CIM-OSA or as implemented at Loughborough University of Technology by the Systems Integration Group as the CIM-BIOSYS (Computer Integrated Manufacturing Building Integrated Open Systems) integration infrastructure.


Objectives: The purpose of this study is to investigate the effect of herbal medicine treatment for glucose and lipid metabolic abnormalities caused by polycystic ovary syndrome (PCOS).
Methods: We searched for randomized controlled clinical trials (RCTs) in 6 electronic databases and search key words were 'PCOS' and 'chinese medicine' or 'herbal medicine' and 'Metabolic syndrome' or 'glucose' or 'lipid'. The results of the studies were analyzed and the risk of bias was assessed by using Cochrane risk of bias (RoB) tool.
Results: We finally selected 7 studies. In 3 of selected studies, herbal medicine was more effective than western medicine in all outcomes and in other 3 selected studies, herbal medicine was partially more effective than western medicine.
Conclusions: The study provides a basis for applying herbal medicine treatment to patients with metabolic syndrome caused by PCOS and helps developing a treatment protocol of caring patients with PCOS. But the limitation of this study is that the number of studies included is small and lack of uniformity of outcome indicators made it difficult to observe overall interrelationship between indicators.


Describes the collection (Nottingham University Library, MS Mi LM 24) of paintings, drawings, and prints of birds and fishes amassed by two founder-members of the Royal Society and used as a source of illustrations for their publications Ornithologiae libri tres (1676) and De historia piscium libri quartuor (1686). Examines the motivations behind the collection, its arrangement, function, and use, and what this suggests about how natural historians valued pictures and their epistemological significance, especially as signifiers of the structural coherence of nature.


The adrenocorticotrophic function of the pituitary gland may be regulated, to some extent, by the corticosteroids but their precise role is not understood. Sayers & Sayers (1947) proposed the theory that stress causes increased utilization of corticosteroids by the peripheral tissues and that the resulting drop in the blood corticoid concentration acts as a stimulus to the release of adrenocorticotrophic hormone (corticotrophin, ACTH). This negative feed-back hypothesis appeared to become invalid because the development of sensitive techniques for the determination of steroids clearly indicated that stress always results in an increase and never a fall in the blood corticosteroid concentration. However, the possible importance of the blood corticoids in controlling corticotrophic function was re-emphasized by Yates, Leeman, Glenister & Dallman (1961). Their findings were not confirmed in this laboratory and our experimental results (Hodges & Jones, 1963) provided further evidence that the secretion of ACTH in response to stress is independent of changes in the concentration of corticosteroids in the blood. On the other hand Sayers (1957) and Hodges & Vernikos (1959) found that a mild stress stimulus raises markedly the ACTH concentration in the blood of adrenalectomized rats but causes no detectable increase in the blood of intact rats. The pituitary adrenocorticotrophic over-activity resulting from adrenalectomy appears to indicate that corticoids play a part in regulating ACTH release. The experiments described in this paper were performed to investigate further this possibility. Accordingly, pituitary and blood-ACTH and plasma-corticosterone changes were studied in adrenalectomized rats, before and after stress, and with and without replacement therapy with corticosterone.


Myanmar language is one of the low resource languages. There are a few resources that include bilingual sentences. Therefore, there are some difficulties to collect or crawl the parallel sentences. Existing Myanmar Translation systems use rule-based as well as statistical-based approach with the small amount of parallel corpus. Therefore, the performance of Myanmar to English Machine Translation system is still low. In this paper, large scale parallel corpus is prepared and introduces the Myanmar to English Neural Machine Translation system. Nowadays, neural machine translation models became a popular research field and it reaches good results in some languages. In this work, we did the experiment on the word-level model and character-level model based on neural method for Myanmar to English translation. The evaluation results show that neural machine translation models lead to improve the performance of Myanmar to English translation.


The paper deals with the distribution of certain functions of distances between any two points of a line of length unity divided into (n+1) parts by n points taken at random by a unified approach.


Abstract 'Quantified pure existentials' are sentences (e.g., 'Some things do not exist') which meet these conditions: (i) the verb EXIST is contained in, and is, apart from quantificational BE, the only full (as against auxiliary) verb in the sentence; (ii) no (other) logical predicate features in the sentence; (iii) no name or other sub-sentential referring expression features in the sentence; (iv) the sentence contains a quantifier that is not an occurrence of EXIST. Colin McGinn and Rod Girle have alleged that standard first-order logic cannot adequately deal with some such existentials. The article defends the view that it can.


Diabetes mellitus (DM), a chronic disease is frequently comorbid with psychiatric problems/disorders. Identification and management of comorbid psychiatric problems are important for the management of diabetes itself. We lack studies in this regard though we have many patients with diabetes in Nepal. This study aims to determine the prevalence of psychiatric disorders in patients suffering from and seeking help from diabetes clinic. This is a hospital-clinic based prevalence study. The study analyzed response to "General health questionnaire GHQ-12" in 200 (calculated sample size) consecutive patients with diabetes attending a diabetes clinic. Diabetes mellitus diagnosis was made based on "American Diabetic Association" (ADA) guidelines, 2009. Psychiatric disorders were screened with self-response questionnaire "GHQ-12" which provides overall score, the score of 2 or more considered as achieving "psychiatric caseness" indicating overall psychiatric disorder. Among 200 clinic diabetes patients, 136 (68%) had GHQ-12 score of 2 or more, i.e. "psychiatric caseness". By alternate scoring, 15 (7.5%) had severe (25-36), 105 (52.5%) moderate (13-24), 71 (35.5%) mild (1-12) and the rest 9 (4.5%) had nil symptomatology. Among GHQ-12 items, "felt that you couldn"t overcome your difficulties" was the most scored (39.0%), followed by "felt constantly under strain" (37.5%). Psychiatric problem is common among patients with diabetes. Diabetes management should involve diagnosis and treatment of comorbid psychiatric disorders.


In this paper,the bonding technique for the blended wing body mini UAV is presented.The structure characteristics of BWB mini UAV,the main parts and subassemblies in UAV are detailed.The selection of the adhesive,bonding procedure conditions and basic performances of some suitable adhesives to bonding UAV are emphasized on.It describes the bonding processing for UAV assembly,including the joint parts preassembling,the influence factors of surface treatment,different treatment methods for various materials,adhesive spreading,components assembling and adhesive curing etc.After several decades' tests,the application results show that the bonding technique is credible and it meets the flight demands.


EXECUTIVE SUMMARY | This article is written in the memory of Dick Clark, who dedicated a large part of his life perfecting the demand planning process at Procter & Gamble. His life work reminds us to constantly challenge the status quo, always seek knowledge, and share with others Just recently we all heard the news of Steve Jobs stepping down from his operational leadership role at Apple. I remember the times when I wouldn't go anywhere without my Sony Walkman strapped to my side. Now I can sit on my couch and instantly download the latest David Guetta or Avidi releases onto my iPad, iPhone, and iPod. Steve Jobs is attributed with the vision and passion to bring that type of technology to life, just as today MarkZuckerberg brought us Facebook. In all things, there is a passing of the baton as one group breaks innovative ground that becomes the foundation for the next generation to build upon. Maybe a little less sexy and several billion dollars poorer are the Thought Leaders of Demand Planning. A few weeks agooneof my Demand Planners came to me to ask if he could pursue IBF Demand Planning Certification. What seems like a very simple request, something so many Demand Planners at companies around the world may be asking their Managers today, would not have been possible without the thought leadership of Dr. Chaman Jain and people like him. Just ?5 years ago I attended my first IBF Best Practices Conference in Chicago where we were talking about building a better consensus forecast process. Ten years ago I was attending workshops with Colleen Crum and Tom Wallace learning how to implement a Sales and Operations Planning Process. Five years ago people like Lora Cecere were talking about Demand Driven Supply Chains. Today, I can call experts like Larry Lapide, who has worked with AMRand MIT for years to get an insight on how other best-in-class companies are leveraging various capabilities. It is difficult to call out a single individual who has moved the needle that turned Demand Planning from support work to a discipline that now has its own career path up to the Vice President level. But one Thought Leader I want to call out is Dick Clark. Dick recently passed away after a noble fight against cancer. Dick built his career at P&G, like so many others, starting out as an Engineer out of college and moving through the Supply Planning organization. Dick's crowning achievement was becoming the Global Demand Planning Capability Owner at P&G. It is in that capacity that I came to know and work with him. What makes Dick Clark stand out in our profession is that he helped institutionalize much of what we take for granted in our Demand Planning organizations. It is one thing to invent the Apple computer but it is another thing to get people to understand its value and to embrace it. That is what Dick was able to do in the course of his career for Demand Planning. In the area of process and systems, Dick implemented global work processes, Demand Planning colleges, and audit processes. He also recognized that having one global demand planning system offered scale with benefits that regional solutions could not provide. …


Introduction. The development of the sub-regions of the Republic of Crimea is characterized by a difference in the performance indicators of the enterprises of the tourism industry. The paper examines the differences in the efficiency of the activities of tourism enterprises in the Crimean subregions. Resource asymmetry in the region is considered as such reasons. Methodology. As a correlation with the territorial concentration of resources, the return on total capital is used, which characterizes the efficiency of the use of all assets of the enterprise. The study used methods of correlation analysis to establish this relationship, where the factor (cause) indicator is the resource asymmetry of the region. Other methods of statistical research (sampling, data grouping) and general scientific methods (analysis, synthesis, systematization) were also used. Results. As a result of the study, one can note a higher efficiency of enterprises in subregions with a greater concentration of potential. Territorial concentration of potential characterizes unequal conditions for the development of enterprises in subregions. As a result, Greater Yalta, Greater Alushta and Feodosia are developing at a faster pace than other sub-regions of the Republic of Crimea. It has been established that subregions with a high level of concentration of natural and historical and cultural potential are characterized by a higher efficiency of tourism enterprises in the subregions. The result of assessing the dependence of the return on total capital and the level of territorial concentration of natural and historical and cultural potential turned out to be 0.73, which indicates a close connection between the indicators, assessed on the Chaddock scale. Conclusions. The results of the study can be used in planning the development of areas of activity and types of recreation in the Crimean territory in accordance with its resource asymmetry. This study is necessary to assess the prospects for the development of the tourism industry in the region as a whole.


Abstract : A lightweight polyurethane foam insulation for liquid hydrogen tanks of space vehicles was developed that could he foamed in place, did not crack when chilled to liquid hydrogen temperature, and had a thermal conductivity of 0.0137 W/(m)(K) (0.0079 Btu/(hr)(ft)(R)) at a mean temperature of 136 K (243 deg. R). The foaming-in-place technique in which the foam constituents were poured directly on the tank, coupled with the specific foam formulation, produced a 34.4-kg/cu m - (2.14-lb/cu ft) density foam that remained structurally intact during all simulated ground-hold vibration, and space-hold tests conducted. Thermophysical properties of the foam were determined, and thermal stress profiles throughout a layer of insulation were calculated.


A 5.4-km stretch of the M50 is the first UK motorway to be renewed using an asphalt material called Glasphalt developed by RMC Aggregates. Glasphalt contains 25% finely crushed waste glass. Although Glasphalt is not fully approved for motorway use under the Highway Authorities' Product Approval Scheme (HAPAS), the Highways Agency granted a dispensation for it to be used. Glasphalt includes an adhesion agent, but is laid in the same way as traditional macadam. On the M50, seven different thicknesses of base and binder course material were specified in different areas. The most deteriorated sections and areas of heaviest use underwent full depth reconstruction. The material was laid using a conventional tracked paving machine. Cores of the new surface were taken at 500 m intervals for quality control.


In the field of transportation, among the terrorist activities against highway structure, about 60% comprised of explosive attacks which highlight the necessity for blast resistant structures. Even though there is only a very small chance of terrorist attacks directed against a bridge, the economic and social penalties of such attacks can remain awfully high. There have been only few significant researches carried out in the area of blast against bridges. Experimental and analytical researches on blast load analysis are necessary to assess the efficiency of existing guidelines for blast resistant design practices of bridges. The present study aims to model the bridge in Finite Element Modeling (FEM) software ABAQUS and to conduct a parametric study on the effect of blast load on the model to obtain the response of the bridge components. The parameters for analysis are stand-off distance and location of blast. Analysis is done to quantify the effect of blast loading on bridge. When the stand-off distance increases, the maximum displacement as well as stress decreases.


This thesis explores male sexual assault and sexual harassment perpetration. The theoretical orientationswere constituted of a theoretical synthesis of primarily Max Weber's theory of action, motiv ...


With all the brisk growth of web, distributed denial of service attacks are becoming the most serious issues in a data center scenarios where lot many servers are deployed. A Distributed Denial of Service attack gen- erates substantial packets by a large number of agents and can easily tire out the processing and communication resources of a victim within very less period of time. De- fending DDoS problem involved several steps from de- tection, characterization and trace back in order todomiti- gation. The contribution of this research paper is a lot more. Firstly, flooding based DDoS problems is detected using obtained packets based entropy approach in a data center scenario. Secondly entropy based trace back meth- od is applied to find the edge routers from where the whole attack traffic is entering into the ISP domain of the data center. Various simulation scenarios using NS2 are depicted in order to validate the proposed method using GT-ITM primarily based topology generators. Infor- mation theory based metrics like entropy; average entro- py and differential entropy are used for this purpose.


Interacting quantum many-body systems often generate exotic orders, either topological or conventional competing orders. Understanding these phases and the phase transitions between them are common issues in condensed-matter physics. How to characterize these states in a convincing and convenient way remains ambiguous. Here, we report our numerical study on the interacting $\ensuremath{\nu}=\frac{1}{2}$ hard-core boson system with topological flat bands based on the infinite density matrix group algorithm. We explicitly show that the entanglement spectral flow can be used to diagnose the quantum phases emerging in the hard-core boson systems. In particular, the subsequent charge pumping exhibits a linear, sinelike, and indiscernible dependence by the flux threading in the fractional Chern insulator, supersolid, and solid state, respectively. The real-space boson occupancy in the thermodynamic limit is further calculated for a better understanding of the respective state. We compare the phase diagram obtained here with that obtained by the previously exact diagonalization method, and qualitative differences are observed. Therefore, the infinite density matrix group algorithm provides a convincing and convenient way to study the phase transition in such a strongly correlated topological system.


The thesis introduced howto use remote sensing interpretation of the related geological factor and geological route selection of railway by use of 3D visualized image which produced by remote sensing technique,it analyzed and contrasted the engineering geological condition of railway.It has an certain reference value for actual application.


ObjectiveTo observe the effects of naloxone on the plasma levels of endothelin-1 (ET-1),calcitonin gene related peptide(CGRP) and S-100 B (a kind of nervous tissue protein) in patients with traumatic brain injury(TBI) and investigate its therapeutic efficacy for patients with acute TBI.The plasma level changes of ET-1 and CGRP in patients with TBI were estimated by radioimmunoassay (RIA) and those of S-100B was detected by ELSIA.①The plasma levels of ET-1 and S-100B increased significantly at 1st,3rd and 5th day after TBI ; the more was the severity of injury, the more prominent was the elevation. ②The plasma levels of ET-1 decreased more markedly after the therapy of naloxone than those of controls,but the increase of plasma CGRP levels was more obvious than the controls in the early period (1st day). ③The plasma levels of S-100B in patient with TBI distinctly increased, the degree of increase was dependent on the severity of brain injury.[Conclusions]①The increase of plasma ET-1 and S-100B levels is related with the severity of trauma. ②Imbalance of ET-1 and CGRP plays an important role in the pathological process of TBI. .③Early application of naloxone can remarkably decrease the plasma levels of ET-1 and S-100B, elevate the plasma levels of CGRP and get satisfactory therapeutic efficacy in patients with TBI.


The paper analyses combinative incentive contract,including implicit incentive contract based on subjective performance and explicit contract based on objective performance to entrepreneur human capital.The implicit incentive contract and explicit incentive contract models are given firstly.On the base of static analysis,the change meaning of relative parameters in the model is deeply discussed and the significance of combination incentive contract is that the expected gains of the entrepreneur and the owner are increased under the restraints.


An expert system is a computer program that is knowledge-based intelligent system. Expert system use human knowledge incorporated into the computer to solve problems that generally require the expertise of an expert using inference techniques. The knowledge base is the most important element of an expert system, derived from a variety of sources documented or from experts.The limitations of experts (time and cost) to carry out the acquisition of knowledge and the rapid development of knowledge, it would require other sources of knowledge that can support expert system in order that the expert system can always actual. The knowledge from the public is one way that can be done to obtain the knowledge for an expert system. The knowledge gained must be suitable with the pre-existing knowledge in an expert system to maintain the quality of expert system. The expert system that implement public participation to obtain or sharing the knowledge, consists of 2 knowledge bases namely : expert knowledge base that contains the knowledge derived from expert (supporting knowledge element) and public knowledge base that contains the knowledge derived from the public (prior knowledge element). Supporting knowledge are used as a reference to estimate, select and assess new facts that occurred in the field to estimate erosion factors and the effects of erosion, and also used by expert system to determine the suitability between new facts from the public and the knowledge of the expert system. Prior knowledge is knowledge from the public that has been known or has been through the testing process. New facts examination carried by comparing between the correspondence truth of the giver of knowledge (public) and the coherence truth received of knowledge or expert system and compare the level of confidence with Dempster's rule of combination. New facts that can be accepted if there are suitable and low coefficient of conflict (K). Determination the level of erosion using USLE equation and visual observation to know the effects of erosion in the field. Field observations carried out at the national park of Mount Merapi Kaliurang, south part of the district of Sleman in 5 different locations (25 km from Yogyakarta) with an altitude of
approximately 600 m above sea level. Soil type is regosol with annual rainfall
average is 1582 - 2140 mm for 30 years (1981-2010).
The test results show that the new facts from the public as the result of
impact of erosion that occurs in the field are suitable or related to the level of
erosion generated by the expert system except at location 5. At location 5, level
of erosion generated by the expert system is moderate, however the impact in
the field included in the criteria is severe erosion level, so that the impact can
not be accepted as new knowledge by expert system because it had not caused
by moderate erosion. Several advantages from expert system that implement
public participation to obtain or sharing the knowledge such as: can ease the
burden of experts, the knowledge base is dynamic, it can be used in a longer time
period and more efficient than the existing expert system. There are several
obstacles that may be encountered in this expert system such as: lack of clarity
each criteria on supporting knowledge, supporting knowledge is not renewed,
the vagueness of conclusions given to the public and access to expert system.


Purpose
This paper aims to analyze the regional distribution, size and evolution of the knowledge base by identifying key authors, documents, keywords and journals while examining current literature and intellectual structure, and highlight topical trends of green human resource management (GHRM) research.

Design/methodology/approach
As scholarly interest in the environment has grown, a new research focus in the discipline of human resource management (HRM) has emerged. The term GHRM was coined to describe how HRM may contribute to environmental outcomes. This scholarly focus has led to an increasing number of publications in this field. To analyze the intellectual structure of the GHRM research, a bibliometric technique is used.

Findings
The findings revealed a knowledge base that is still in the new phase, with a global scope, but most scholarly work is concentrated in Asian societies. By presenting an overview of the present state of the knowledge base, this study intends to lead a new generation of GHRM scholars.

Originality/value
To the best of the authors' knowledge, this is the first study of its kind, which probes the bibliometric reflection on green human resource management research history.


Based on inspection of the failure phenomenon of the real estate enterprises from the empirical perspective,the author seeks for the law behind the failure problems of the real estate enterprises from all aspects in the running course of the enterprises,trying to build the predictive model of the real estate enterprises in order to warn the enterprises before they fail,and then take corresponding measures actively to reduce the possibility of failure.


Emotion is of great significance in human's daily interaction. Contemporarily, emotion recognition systems are beneficial in various areas, ranging from human-computer interaction (HCI) system to healthcare safety. So far, the Electroencephalogram (EEG) has received much attention because of its sensitivity to mood changes. However, the relationship hasn't been fully researched. To investigate the relationship among emotions, bands, channels and find a better classifier, this experiment organize the framework based on the DEAP dataset. After the data preprocessing, EEG data is reduced by principal component analysis (PCA). Then to create the emotion feature vectors, the discrete wavelet transform (DWT) is chosen as the parameter. Lastly, to categorize the EEG signal, support vector machine (SVM), random forest (RF), k-nearest neighbor (KNN), XGboost model is created. According to the experiment, this paper obtained the following relevant conclusions: 1) RF, SVM, KNN and XGboost classifier, performed with the accuracy of 77.01%, 80.44%, 66.75% and 77.75%, respectively; 2) In temperal and whole brain regions, gamma has the highest recognition ability, reaching 76.770/0 and 77.02%. The beta performs best in occipital, parietal, and central regions with 78.00%, 77.26%, and 78.00%, respectively; 3) The higher the frequency, the greater the oscillatory dynamics of brain activity on positive / negative emotions; 4) The AF3, AF4 area has a greater effect in reflecting emotions because of less irrelevant influences.


The sensitivity of eigenvalues of structured matrices under general or structured perturbations of the matrix entries has been thoroughly studied in the literature. Error bounds are available, and the pseudospectrum can be computed to gain insight. Few investigations have focused on analyzing the sensitivity of eigenvectors under general or structured perturbations. This paper discusses this sensitivity for tridiagonal Toeplitz and Toeplitz‐type matrices.


The paper investigates the problem of L_2-L_∞ filtering for a class of stochastic linear repetitive processes.Attention is focused on the design of full-order filter guaranteeing mean-square asymptotical stable of stochastic linear repetitive processes and a prespecified L_2-L_∞ performance γ for the filtering error processes with respect to all energy-bounded input signals.Sufficient conditions are proposed in terms of linear matrix inequality,and the corresponding filter design is cast into a convex optimization problem.A numerical example illustrates the effectiveness of the proposed design scheme.


We present a quite efficient method to compute the roots of Bernstein-Sato polynomial of a homogeneous polynomial if the associated projective hypersurface has only weighted homogeneous isolated singularities (so that its local Bernstein-Sato polynomials are uniquely determined by weights) and if a certain condition is satisfied. In the three variable case, the last condition holds except for polynomials of quite special type (that is, extremely degenerated ones) as far as calculated. The computation of roots is reduced to that of the Hilbert series of graded Milnor algebras, which can be done instantly by computers (unless the degree is huge), although it takes much longer to get the Bernstein-Sato polynomial itself (that is, with multiplicities) using a computer program in general. For the proof of the formula, we prove the $E_2$-degeneration of the pole order spectral sequence. We have a simpler formula for the roots of Bernstein-Sato polynomials if the projective hypersurfaces have only ordinary double points or the Tjurina number is relatively small.


We examined the response of microbial communities in the model sea anemone Exaiptasia diaphana (Aiptasia) to short-term thermal elevation. Through 16S rRNA gene sequencing, we characterized the microbiomes of symbiotic (with algal symbionts) and aposymbiotic (bleached) anemones under ambient (27°C) and heat-stressed (34°C) conditions for 8-10 days, using both replicated endpoint and non-replicated time-course approaches. Consistent with prior studies, we observed a stable abundance of bacteria from the families Alteromonadaceae and Rhodobacteraceae, though with wide variation among individual anemones. We observed that symbiotic state conferred a larger impact on the microbiome than heat stress, implying the microbiome may play a metabolic role in the maintenance of cnidarian-dinoflagellate symbiosis. In particular, Pelobacter, an anaerobic sulfate reducer that is also a potential nitrogen fixer, was present only in symbiotic anemones, and its abundance decreased with initial exposure to 34°C, but recovered after 7 days. In aposymbiotic anemones, the added heat stress appeared to result in a large increase of rare bacterial taxa, which included potential pathogens such as Vibrio following bleaching. We also observed several archaea, the first reported for this model, but only in the seawater surrounding aposymbiotic Aiptasia, where abundance increased dramatically following heat stress. We further explored the diazotrophic (nitrogen fixation) potential of diverse bacteria associated with symbiotic and aposymbiotic Aiptasia, under both ambient and heat-stressed conditions, using nifH-PCR and qPCR and the acetylene reduction assay (ARA). In contrast to some stony corals, nifH was barely expressed in both anemone types, and under ambient conditions, diazotrophic activity was not detectable via ARA. Thus, although this research contributes to the growing knowledge of the bacterial community associated with a prominent model used in coral-symbiosis research, our results also suggest using caution when making direct comparisons between Aiptasia and different coral species in microbiome studies.


Tallo watershed has a length of 70 km, its area width is 407.00 ¬¬km2, the river upstream or downstream is at an altitude of ± 1,100 m above sea level located on Mount Kaliapolompo in which the overall length of the river in Tallo watershed totaling ± 131.50 km2. The research objective was to analyze the effect of five-year flood discharge and tidal changes on the inundation area and flood depth in Tallo watershed. The method of rainfall analysis used the Log Pearson type III method where the flow is considered to be two horizontal dimensions with even velocity at each depth. A five-year period with a discharge value of 127.64 m3/s will statistically reoccur every five years with an estimated chance of occurrence of 0.2 or 20% for each year referred to in a 5-year review cycle. The results of the simulation were then known that the five-year flood discharge resulted in flooding with a depth of 0-3 meters from the maximum tide condition (HWSL), and an inundation area of 31.91 km2 inundated the Tallo District, Tamalanrea District, Panakukang District, West Biringkanaya District and northern Manggala District. These areas are located on the left and right of the Tallo River with an altitude between 0 and 2 meters above sea level.


This COVID-19 pandemic is impacting the world in health and economic terms since 2020 with more than 200 million confirmed infected people and more than 4 million deaths across 190 countries. Treatment used against COVID-19 disease has initially been based on the combination of several medicaments, such as hydroxychloroquine/chloroquine, azithromycin and kaletra, each of which can individually delay the ventricular depolarization and repolarization processes through morphological changes in the patient's electrocardiogram. These changes can produce serious arrhythmias that lead to the sudden death of the patient.This paper presents an interpretable fuzzy rule-based system for fatal ventricular arrhythmia risk level estimation due to COVID-19 treatment, whose decisions are made on the basis of the evolution of electrocardiogram morphology and certain patient's clinical information. For the risk level estimation, the proposed fuzzy rule-based system considers three different risk levels (High, Moderate and Low) which are indicated by means of three different colors (Red, Orange and Green). Decisions made by the fuzzy rule-based system present a reliable behavior in comparison with cardiologist's decision. To be precise, the obtained accuracy, when comparing both decisions, reaches the 96.43%, which, joint to the high measured interpretability of the decision making system, result in a powerful tool in order to avoid death in patients, even in health centers without specialized clinical staff, and to reduce the stress in medical centers by reducing reaction times in critical patient situations.


Each of 3 genotypes were sown on 5 dates. Infection by B. cinerea in cv. Dhanush was significantly lower than in ICCV1 (Sita) and ICCL82108. Sowing dates also showed significant differences in infection intensity and when compared with a given sowing date each subsequent date reduced grey mould significantly. There was a significant interaction of genotypes with sowing dates.


. Let (E, p, X) and (F, q, Y) be Banach bundles. A bundle transformation from (E, p, X) into (F, q 9 Y) is a. function F : E— > Ffor which there is a base map/ 0 : X'-* Y with f 0 ° p = q of and for which f x = f\p-u X ) is a linear transformation from p~ x (x) into q' 1 (fo(x)) for each x in X. It is proved that if f : E -> F is a bundle transformation which preserves relatively compact sets and X is locally compact, then / is continuous if and only if the graph of fis closed. An example is presented in order to show that there is no general open mapping theorem for Banach bundles.


The financial model for derivatives with counterparty risk is considered.The firm value model is applied to price European type options for derivatives with counterparty default risk. The martingale approach is used to derive an explicit pricing formula for such Black-Scholes option under the Gaussian assumptions,which generalize the results in[1](Ammann,2001).


This thesis describes the application of pharmacometrics to optimize treatment with existing therapies and to support development of novel drugs in the area of oncology. In the field of pharmacometrics, data on pharmacokinetic (PK) and pharmacodynamic (PD) properties of drugs are characterized using a combination of mathematical and statistical models. These properties give insight in the fate of a drug in the body (PK) and in its desired and undesired (toxic) effects (PD). Quantification of PK-PD relationships in mathematical and statistical models allows for understanding the characteristics of a drug. Additionally, these models can help answer questions to improve clinical application of drugs and supports decision making in drug development. This thesis describes various examples of applying modeling and simulation methods to improve current treatments and support development of new drugs in oncology. Chapter 1 focuses on the pharmacology of tamoxifen and strategies to individualize dosing of tamoxifen by applying dose adjustments based on endoxifen concentrations. In chapter 2 a pharmacometric approach is used to determine a first-in-human dose for a novel monoclonal antibody and to evaluate its pharmacokinetic properties. In chapter 3 PK-PD modeling is performed to describe pharmacodynamic properties (i.e. toxicity) of different anti-cancer drugs, such as anthracyclines, trastuzumab and docetaxel.This thesis demonstrates that pharmacometrics provides powerful techniques to answer (clinical) pharmacological questions that are often impossible to answer using conventional statistical methods. The examples in this thesis, are applied to the therapeutic area of oncology, though can in part also be applied to answer pharmacological questions in other therapeutic fields and contribute to improved and safer drug treatment in patients.


An Inverted double pendulum is a combination of two individual pendulums which represents an example of a nonlinear and unstable dynamic system and it is also a good example of a physical system wh ...


The sinter returns is more and more with the ferrous materials changing in Zhuye 60 m~2 sintering plant.And it is difficult to decrease sinter energy consumption.In this paper,the reasons causing higher sinter returns rate were analyzed.After a series of measures were adopted,the satisfactory effect was obtained.


RESPECT THE INVENTION A SET A FUEL FILTER CARTRIDGE FOR FILTER, AND COMBINE WITH SEPARATE COALESCENCE SOLID IMPURITIES, LIQUID AND GAS FLUID. INCLUDES THE DEVICE CARTRIDGE 40 INCLUDING A PORTION OUTER RING FILTER INNER RING AND PART COMBINATION BY COALESCENCE WHERE LIQUID fORM emulsified droplets CAN BE EASILY ELIMINATED FLUID POWER. SEPARATOR 60 IS AVAILABLE WITHIN THE PART COMBINATION BY COALESCENCE TO DEVIER LIQUID OBTAINED COALESCENCE WHILE ALLOWING PASSAGE PURIFIES FLUID SCOPE. FILTERS MOTOR FUEL VEHICLE, ETC.


According the situation that the teathers who aftend the distant training write a post and reply at the BBS(Bulletin Board Service),the paper analyses the motives of the elementary and middle school teachers who attend the distant professional training.The study motives include many kinds from the view of Maslow's level theory of human need,and they change extremely according to the circumstances.In order to raising the effectiveness of the distant training through the internet,the paper tentatively puts forword the corresponding solutions.


brokenness. Across these chapters we learn that the militancy of God is found in the ability to resist human beings' rejection of one another: 'Real political insurrection ... demands rooting the dismissal and "othering" from the human hearts out of which it springs' (p. 11). The historian and biblical scholar in me wishes that Brock had interacted with more biblical and early church scholarship than he does. In the past ten years, disability criticism has made inroads into these areas of theological inquiry and it is disappointing that Brock does not utilise this material. This is a highly subjective quibble, however. Brock is speaking with confidence about the paradoxes in modern medical thought and practice and about the uneasy way in which modern Christians have adopted secular consumeristic assumptions. His is a powerful call to arms: to resist the social and cultural structures that induce us to distance ourselves from other and to accept the powerful command of the spirit to receive and embrace others. All of this he grounds in a richly developed incarnational theology of the flesh that is practically brought to bear upon the practices of societies and communities that should know better.


This essay deals with some key Italian contributions to econometrics in the twentieth century. It opens with some notes on the need to define and measure each dimension of the manifold notion of well-being. While considering the convinced supporters of the methodological adoption of tools devised by economics and statistics, the central part of the essay focuses on Corrado Gini (1884–1965). He was Italy's leading econometrician and the main reference of the international network of econometricians until the 1940s. Other Italian members of the newly formed Econometric Society are also cited, specifically Luigi Amoroso and Umberto Ricci, because of the relevance of their contribution. The essay concludes by referring to Gini's rejection of econometrics, which coincided with the appearance of a new generation of social scientists whose aim was to combine economics, statistics, and mathematics.


The connector of the present invention provides an environmentally sealed connector (10) for terminating a coaxial cable (24). The connector is useful with hard-line or semi-rigid coaxial cables. Multiple o-rings (13,74,186) provide environmental seals upon securement of the connector to the coaxial cable.


At present, the income gap between urban and rural areas in our country is becoming larger, as causes the enormous rural-urban population migration which aggravates the high level of urban unemployment. This paper first carries on the theoretical analysis on this fact using Todaro model, then conducts empirical analysis on the fact that the income gap between urban and rural areas aggravates the high level of urban unemployment by means of Granger causality test, finally puts forward the policies to alleviate the pressure of urban unemployment through the construction of new socialist countryside in short run.


Upon agreeing to review The Geopolitics of South Asia, this reviewer expected to receive a serious scholarly work on the way the geography of the South Asian region has fundamentally affected the formation of states and empires that litter the area's history, from the earliest Mahajanapadas (States) to the current countries of Pakistan, India, and Bangladesh. This, after all, is the way this reviewer understands the conceptualization and definition of the term 'geopolitics'. Indeed, the author himself offers a similar definition, writing in the foreword that the book's central theme is '... the relationship between society and the organisation of territory ... and the development ... of the ever-changing pattern of states' (p xii). This reviewer expected to read a detailed analysis of geographic regions and subregions, of core and peripheral areas of state and empire formation, and the way which the geographical divisions between these areas contributed to the development of the cultural and linguistic diversity that is South Asia. This reviewer's expectations were disappointed. This disappointment began with the cover illustration of a bearded goonda (thug) caught in mid-yell, brandishing an iron pipe like a sword, with bright orange flames in the background. The impression given is that South Asia is a troubled place, always teetering on the brink of instability, anarchy, and collapse, and the image is at variance with the brief editorial blurb appearing before the title page which extols South Asia as '... one of the world's great cultural heartlands' (p i). This book is plagued by a number of such disconnections. First, apart from a fairly good map (Figure F1), there is little or no discussion of regions and subregions, and their impact upon South Asia's historical development. Second, the book's subtitle overstates the book's contents. Rather than a balanced overview of South Asia, we are presented with a lopsided one, in which pre-British India is relegated to only three chapters. The next five chapters are devoted to the British Raj and partition. The final three chapters deal with the successor states. The final chapter treats the geopolitics of South Asia, but only in the international scene. The subtitle is also an overstatement regionally: state formation in South India, which was home to such empires as the Chola, Pandya, Chera, and Chalukya, is not dealt with. Vijayanagar gets a mere paragraph. In constructing empires and polities in South Asia, Chapman mentions the twin concepts of identitive and coercive bonds. While the latter is readily understood, the former is not adequately explained by the author. In the first eight chapters of the book, Graham Chapman provides what is essentially a history of South Asia to 1947. From a historical perspective, his account is somewhat dated, since it concentrates on high politics. It is also highly Anglo-centric. The old saw that the East India Company was only interested in trade and never in domination often appears in Chapter 4. A decidedly whiggish tone prevails, as for example, when describing Elizabethan England as a modernizing state, and in saying that Britain in 1877 had democratic government. The author obviously does not know basic British history, as analysed in Conrad Russell, The


Context: Recent empirical studies have shown quantitatively how software build systems, which are responsible for converting software artifacts into an installable deliverable for the end user, induce considerable overhead on software developers, taking away their focus from actual development.
 Goal: Little, however, is known of what are the typical types of changes that these developers need to make to build systems, the characteristics of these changes and whether developers work on these changes by themselves, or are co-ordinated by build experts.
 Method: This paper qualitatively investigates the build commit history of 18 open-source projects from the Apache and Eclipse eco-systems, over a period of fourteen months, using manual tagging and classification of change types and build system ownership styles.
 Results: "Corrective", "Adaptive" and "New Functionality" build changes introduce considerably higher churn and are more invasive, while many changes are identified by accident during regular development. Having dedicated build experts allows software projects to make more invasive "Adaptive" changes.
 Conclusions: Build system studies need to take into account the type of build change, since not all build changes are equal.


Abstract This article aims to present, in general terms, the phenomenon of employee turnover in Mexicali, Baja California, which is a Mexican city located on the US–Mexico border. This phenomenon has impacted the economy of many firms, and the entrepreneurs expressed their concern though different fora and media. For this purpose, important regional actors participated in focus groups sessions. During these sessions, they explained the impact of this phenomenon on their firms and how they have been dealing with it. As a result of the interaction during the focus group sessions, a model to attract and retain employees was developed. The model identifies 12 relevant variables that impact the employees' performance. This study aims to lead to more detailed researches; based on these variables, employers and academicians would apply it in a different context, obtaining comparable results.


Plants have the ability to change their morphological and physiological traits in response to environmental variations. The objective of this study was to determine the intraspecific morphological variations among the populations of M. excelsa, P. adolfi-friedericii, and P. africana in southwest Ethiopia. Representative forests were systematically selected, and a total of ten transects of 160 m length were randomly laid at 100 m intervals, and 30 quadrats (20 m by 20 m) were laid along each transect line at 50 m intervals. Stem height, DBH, and bole length of trees for each species were measured in each quadrat. The intraspecific morphological variations among populations of each species were computed using hierarchical clustering and principal component analysis (PCA) with R.4.1.3. A total of 55 trees for M. excelsa in four forests, 232 trees for P. adolfi-friedericii in eight forests, and 184 trees for P. africana in five forests were measured. Accordingly, three, five, and three population clusters were identified for M. excelsa, P. adolfi-friedericii, and P. africana, respectively. The analysis of similarity (ANOSIM) indicated the presence of considerable dissimilarity among population clusters for M. excelsa and P. africana but was not significant at

 p
 ≤
 0.05

 (R = 0.9,

 p
 =
 0.17

 ). However, ANOSIM indicated the presence of considerable dissimilarity among population clusters of P. adolfi-freidericii, which was significant at

 p
 ≤
 0.05

 (R = 0.9,

 p
 =
 0.03

 ). Overall, there was a visible morphological variability among the populations of M. excelsa, P. adolfi-friedericii, and P. africana each at the different sites. Therefore, it is important to look for conservation strategies, such as domestication, to maintain and improve the variability and genetic quality among the populations in a wider scale of the ecological and social environment.


This book reviews the medical, legal, and theological aspects of abortion as they exist in the various parts of the world. In a fourth section, entitled "Implementing a Social Position," Callahan reflects on the way a knowledge of these facts can help both the individual and her counsellor (and society as well) find a more satisfactory solution for unwanted pregnancies than that of abortion. In the medical section, the author reviews the biological and psychological problems leading to requests for abortion, citing the changing frequency and usage of these designations in support of the termination of pregnancy. He then traces the changing attitudes of society as reflected in the legal codes regulating abortion practice. It is of interest to note that several societies (Eastern Europe and Japan) which were the first to develop relatively unrestrictive laws have subsequently moved toward a more restricting position, partly on the basis of a


: We propose and demonstrate an external optical modulation method based on TE/TM-mode absorption nulls in a Multiple Quantum Well (MQW) Fabry-Perot laser diode (FP-LD). The center wavelength of the absorption nulls is rapidly shifted to short-wavelength by the small current change (~ 1mA) in the FP-LD, which can modulate optical signal with more than 10 dB of extinction ratio (ER). The shift of the center wavelength comes from the refractive index change due to anomalous dispersion and plasma effect in MQW FP-LD waveguide. Non-inverting and inverting signals are made by TE- and TM-mode absorption nulls at 155.52 Mbps and BERs for the signals are measured, respectively.


Abstract. The inverse analysis was used to estimate the fire carbon emission in Equatorial Asia induced by the big El Niño in 2015. This inverse analysis is unique because it extensively used high-precision atmospheric mole fraction data of carbon dioxide (CO2) from the commercial aircraft observation project. By comparisons with independent shipboard observations, especially carbon monoxide (CO) data, the validity of the estimated fire-induced carbon emission was elucidated. The best estimate, which used both aircraft and shipboard CO2 observations, indicated 273 Tg C for fire emission during September–October 2015. This two-month-long emission accounts for 75 % of the annual total fire emission and 45 % of the annual total net carbon flux within the region, indicating that fire emission is a dominant driving force of interannual variations of carbon fluxes in Equatorial Asia. Several sensitivity experiments demonstrated that aircraft observations could measure fire signals, though they showed a certain degree of sensitivity to prior fire-emission data. The inversions coherently estimated smaller fire emissions than the priors, partially because of the small contribution of peatland fires, indicated by enhancement ratios of CO and CO2 observed by the ship. In the future warmer climate condition, Equatorial Asia would experience more severe droughts and have risks for releasing a large amount of carbon into the atmosphere. Therefore, the continuation of aircraft and shipboard observations is fruitful for reliable monitoring of carbon fluxes in Equatorial Asia.


The effect of high pressure on thermal diffusivity of mashed potatoes and olive oil was studied at a temperature range about 25–100 °C. The preheated sample filled into a cylindrical Cu cup was loaded by nominal pressures of 400 and 500 MPa in a high-pressure chamber. The thermal diffusivity was estimated from the time–temperature decay during pressure holding time. Temperatures were measured at three different positions in the sample (wall, centre and at given radial distance). The recorded time–temperature profiles were compared with the prediction of a finite-element model assuming the linear temperature dependence of thermal diffusivity. Wall temperature data were used as a boundary condition. The difference between the measured and the calculated temperatures at the sample centre was minimised by the Marquardt Levenberg algorithm, giving optimal values of the model parameters A and B. Thermal diffusivity for both samples increased with temperature. The thermal diffusivity of mashed potatoes increased with pressure. The thermal diffusivity of olive oil decreased with pressure.


The paper reflects justification of the local government subsidy to the organizations dealing with the management of professional sport and professional culture in Brno. The main assumption of this topic is the problem of comparing the subsidy to the professional sport which is represented mostly by the profitable market entities and to the non-profitable cultural institutions which are state-funded institutions established by the respective city (in this case - city of Brno). The article is focused on the organizations with the biggest budget represented by HC Kometa Brno (ice hockey) and FC Zbrojovka Brno (football) in the field of sport and in the cultural field by National Theatre of Brno, Brno City Theatre and Philharmonic Orchestra of Brno. The fundamental aspect is based on the assumption that the city should provide its inhabitants with the environment supporting them to visit professional sport competitions as well as presentation of professional high culture. Thus, the crucial problem is the justification of subsidies into professional sport, which was after 1989 transformed mostly into the market good at the expense of professionally run art, which is on the contrary since 90s fully financed by the local self-government (districts or municipalities). The key data, used for this project, consist of the overall presence, budgets, form of financing and background for running. Apart from this, here is a polemic on including both of these sectors in chapters of the public budgets in the framework of public economy.


Multi-component induction logging provides great assistance in the exploration of thinly laminated reservoirs. The 1D parametric inversion following an adaptive borehole correction is the key step in the data processing of multi-component induction logging responses. To make the inversion process reasonably fast, an efficient forward modelling method is necessary. In this paper, a modelling method has been developed to simulate the multi-component induction tools in deviated wells drilled in layered anisotropic formations. With the introduction of generalized reflection coefficients, the analytic expressions of magnetic field in the form of a Sommerfeld integral were derived. The fast numerical computation of the integral has been completed by using the fast Fourier–Hankel transform and fast Hankel transform methods. The latter is so time efficient that it is competent enough for real-time multi-parameter inversion. In this paper, some simulated results have been presented and they are in excellent agreement with the finite difference method code's solution.


One problem of Web 2.0 applications lacks intelligence to cope with the XML-based documents transcoding. This study attempts to integrate Semantic Web technologies into Web 2.0 Mashups by defining a semantic-based Web2.0 Mashups framework, which is developed based on Service-Oriented Architecture (SOA) to ruling out heterogeneous effects. Based on the proposed framework, Semantic-based Transcoding Mashup Server (STMS) is also developed to facilitate finding useful Web 2.0 Mashups to achieve Web 2.0 documents transcoding. To demonstrate the feasibility of STMS, an application scenario of the semantic-based mashup transcoding is implemented to convert map pages into various display platforms. Additionally, the study also realizes how Semantic Web and Web 2.0 Mashups can complement each other.


This paper presents robust controller design for damping of inter-area mode oscillations in three machines WECC test system by Static Var Compensator (SVC) using global signal. The stabilizing signal is obtained from phasor measurement units (PMUs) located in all areas of test power system. Residue analysis is carried out to decide the best control signals for damping of critical mode. H∞ loop shaping technique is used to design the damping controller. Various load models representing the different composition of loads are considered for checking the robustness of the designed controller. Robustness of the designed controller is assessed in frequency domain and via non linear time domain simulations for various contingent conditions. The performance of the designed controller is found satisfactory in damping critical mode oscillation under various critical operating conditions.


This paper offers a convenient method to grow good quality of GaAs films at low-temperature ( LT ) , 425 /spl deg/C, by using conventional metalorganic chemical vapor deposition ( MOCVD ) growth technique and taking tertiarybutylarsine ( TBAs ) along with triethylgallium ( TEGa ) as the epitaxial sources . By taking the results from 77 K PL and double crystal X-ray, the film grown at 425 /spl deg/C has shown a full width at half maximum ( FWHM ) 8.2 meV and 14 arcsec . These results indicate that high quality of GaAs films can be obtained by using conventional MOCVD technique without setting any extra and external equipments.


BACKGROUND: Vitamin D deficiency in neonates is associated with neonatal sepsis incidence. It is also significantly correlated to the increased risk in the outcomes of sepsis, such as mortality, length of hospital stay, and use of ventilatory support.

AIM: The aim of the study is to observe the relationship between Vitamin D levels and clinical outcomes of sepsis in the neonatal unit.

METHODS: An analytical cross-sectional study was conducted to neonates in neonatology Haji Adam Malik hospital from June 2019 to February 2020. A Chi-square test was carried out to observe the relationship between Vitamin D levels and sepsis outcomes, and a Mann-Whitney test was done to assess the significance between Vitamin D levels and length of hospital stay.

RESULTS: Among 41 full-term and pre-term neonates, there were 75.6% (31/41) neonates with Vitamin D deficiency, while 24.4% (10/41) had normal Vitamin D levels and did not suffer from deficiency. The relationship of Vitamin D levels with mortality, use of ventilatory support, length of stay, and blood culture was p = 0.660 (95% confidence interval [CI] = 0.810–1.677), p = 0.013 (p < 0.05), p = 0.940 (median 21 days), and p =0.712 (95% CI = 0.623–1.353), respectively.

CONCLUSION: Vitamin D deficiency had a significant relationship with ventilatory support requirement as one of the sepsis outcomes in neonates.


The 3D numerical simulation of the co-rotating disc cavity with the de-swirl nozzles was carried by the RNG k-e turbulence model with three kinds of de-swirl angles(90°,60°,and 30°).The influence of the de-swirl angle on the tangential velocity,the pressure loss in the disc cavity and the heat transfer of the rotational disc is discoverd.The results show that as the de-swirl angle reduces,the flow tangential velocity in the disc cavity decreases,the pressure loss in the disc cavity reduces,the local Nur number of the rotational disc surface increases.


perspective of Battlefield Advanced Trauma Life Support (2). We adopt a simple, safe approach to transfer with airway management dictated by the skills of the provider, aiming not to intubate and ventilate, but to oxygenate. Simple measures allow maximum care to maximum numbers, using minimal expertise and minimal devices. Those who attempt tracheal intubation infrequently should only consider this technique if other simpler techniques fail; prolonged attempts at intubation will delay transfer and complicate subsequent attempts at airway management. End-tidal CO2 monitoring should be used where available, including those whose trachea is not intubated, to assess ventilation and cardiac output. Supraglottic airway devices theoretically decrease lower esophageal sphincter tone predisposing to gastric aspiration (3). Bag-valve-mask ventilation affords visualization of vomitus clearly prompting management. Airway manipulation in trauma victims risks triggering the gag reflex potentially worsens the situation. Those victims who can tolerate laryngoscopy without drugs may have brain injuries that will prevent recovery; indeed, some may have insufficient cardiac output to render end-tidal CO2 monitoring useless. In Battlefield Advanced Trauma Life Support 2005, our immediate response teams (which have a physician) have moved away from tracheal intubation and the use of laryngeal airways to needle cricthyroidotomy, as a means of oxygenation for up to 20 min, and subsequent 6-mm tracheostomy tube placement. This would be confirmed both clinically and with end-tidal CO2 monitoring. N. H. Fraser, MBBS, FCARCSI, FRCA


Transmit power control (TPC) has been recognized as one of the effective ways to save energy in wireless devices. In this paper, we demonstrate the energy-efficient distributed coordination functions (DCF) operation of IEEE 802.11a wireless LANs (WLANs) via TPC and physical layer (PHY) rate adaptation. The key idea is to enforce an RTS/CTS frame exchange before each data transmission, and then select the most energy-efficient combination of the PHY mode and the transmit power level for the subsequent data frame transmission to save energy. The performance of the proposed scheme is evaluated via simulation in the ns-2 simulator.


A number of large controlled trials have shown that angiotensin-converting enzyme (ACE) inhibitors reduce mortality and morbidity in patients with chronic heart failure, and can prevent the development of heart failure in asymptomatic patients with left ventricular dysfunction. Research has shown, however, that regardless of the evidence proving the benefits of ACE inhibitors in the management of heart failure, they are still under-used in clinical practice. In their place, newer treatments, such as AT 1 receptor blockers, are being prescribed, despite the lack of conclusive evidence demonstrating their benefits in the management of heart failure. It is therefore recommended that ACE inhibitors should be first-line therapy in all patients with heart failure, unless contraindications are present. The results of the Assessment of Treatment with Lisinopril and Survival (ATLAS) Study suggest that the highest tolerated doses should be used to achieve maximum benefit (up to 35 mg of lisinopril). AT 1 receptor blockers should be reserved for those patients who are unable to tolerate ACE inhibitors. Recent studies suggest that beta-blockers may provide additional benefits in patients with Class II-III heart failure, and that the addition of spironolactone should be considered in patients with severe (Class IV) heart failure.


We demonstrated a significant charge loss by a small DC bias applied to the SONOS gate. This charge loss can be correlated with that of a high-temperature bake. A bias acceleration test can be useful for wafer-level retention screening. The results also suggest that the gate bias for data readshould be set around 0V to minimize the gate read disturbance. More work is underway to investigate the mechanism of charge loss, the recall disturbance in nvSRAM, etc.


Objictive This paper reevaluates the safety of antbacterial drugs by analyzing some reports on the Ad- verse Drug Reaction(ADR)of antbacterial drugs in Heilongjiang province.Method A retrospective investigation was made as to the ADR reports submitted from all parts of Heilongjiang province,and the ADR reports on antbacterial drugs was selected to analyze the ADR types,clinical symptoms,outcome of antbacterial drugs as well as the rational use of them.Furthermore,a preliminary analysis on the cause and effect of ADR was made in ac- cordance with the Cause Effect Evaluation Method for ADR issued by Ministry of Health,PRC.Results 274 of total 570 ADR reports are about antbacterial drugs,accounting for 48.07%.Cause Effect Evaluation:Definitely (7),Probably(84),Possibly(13).Outcome:Cured(55),Improved(48),Sequelae(1),Death(0).Conclusion The ADR monitoring on antbacterial drugs should be strengthened to advocate the rational use of clinical drugs.


Autonomous vehicles increasingly play an important role in daily life. Low-stakes use cases can enable people's familiarity and confidence in these systems, helping to establish public trust. The Neutronomous project aims to enable food and package delivery via a low-cost, easy-to-fabricate one-tenth scale autonomous car. Three Raspberry Pis execute real-time parallel computations for sensing and localization via an environmentally robust LiDAR, and state estimation and high-level planning via an IMU-enabled GPS. This build is ideal for a self-driving robot to navigate college and corporate campuses, as well as small towns. The Neutronomous car's practical and accessible implementation paves the way for continued integration of autonomous vehicles in public spaces.


Mitochondrial fission, regulated by dynamin‐related protein‐1 (Drp1), is a newly recognized determinant of mitochondrial function, but its contribution to left ventricular (LV) impairment following ischemia‐reperfusion (IR) injury is unknown. We report that Drp1 activation during IR results in LV dysfunction and that Drp1 inhibition is beneficial. In both isolated neonatal murine cardiomyocytes and adult rat hearts (Langendorff preparation) mitochondrial fragmentation and swelling occurred within 30 min of IR Drp1‐S637 (serine 637) dephosphorylation resulted in Drp1 mitochondrial translocation and increased mitochondrial fission. The Drp1 inhibitor Mdivi‐1 preserved mitochondrial morphology, reduced cytosolic calcium, and prevented cell death. Drp1 siRNA similarly preserved mitochondrial morphology. In Langendorff hearts, Mdivi‐1 reduced mitochondrial reactive oxygen species, improved LV developed pressure (92±5 vs. 28±10 mmHg, P<0.001), and lowered LV end diastolic pressure (10±1 vs. 86±13 mmHg, P<0.001) following IR Mdivi‐1 was protective if administered prior to or following ischemia. Because Drp1‐S637 dephosphorylation is calcineurin sensitive, we assessed the effects of a calcineurin inhibitor, FK506. FK506 treatment prior to IR prevented Drp1‐S637 dephosphorylation and preserved cardiac function. Likewise, therapeutic hypothermia (30°C) inhibited Drp1‐S637 dephosphorylation and preserved mitochondrial morphology and myocardial function. Drp1 inhibition is a novel strategy to improve myocardial function following IR.—Sharp, W. S., Fang, Y. H., Han, M., Zhang, H. J., Hong, Z., Banathy, A., Morrow, E., Ryan, J. J., Archer, S. L. Dynamin‐related protein 1 (Drp1)‐mediated diastolic dysfunction in myocardial ischemia‐reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB J. 28, 316–326 (2014). www.fasebj.org


CaRuO3 thin films have been grown by on axis sputtering on various (110) SrTiO 3 , (110) LaAlO 3 , and (100) NdGaO 3 substrates. The growth of high-quality twin free samples, having the a axis aligned with the substrate normal, and the b and c axis aligned with the principal in-plane substrate directions, is demonstrated. The mechanism of domain selection is addressed in terms of free energy minimization during the tetragonal to orthorhombic transition, taking into account both strain and surface energy contributions. On the base of experimental data, it is shown that minimization of surface energy plays a major role in determining film orientation. Obtained samples are especially suited for the investigation of anisotropy in the macroscopic properties of Ca/Sr ruthenates.


 Citation: Borna H, Dehghani R, Fazeli-Dinan M, Hosseini-Vasoukolaei N, Jahani H, Yazdani Cherati J, Motevalli Haghi F. Some Epidemio-logical Aspects of Scorpionism in Qaenat, Iran, during 2011-2016. Journal of Health Research in Community. Winter 2019;4(4): 63-72. ABSTRACT Introduction and purpose: Scorpion stings can threaten human health. The investigation of the epidemiologic factors affecting scorpion stings plays an important role in the prevention of this public health issue. Therefore, this study was conducted to investigate the epidemiology of scorpionism in Qaenat city, South Khorasan Province, Iran. Methods: This retrospective cross-sectional study was conducted on all the stung people residing in Qaenat city of South Khorasan Province during 20112016. The epidemiology of patients and demographic data were collected in a checklist and data were analyzed in SPSS (version 20). Results: A total of 164 cases stung by scorpion were enrolled in the present study, including 75 males (45.7%) and 89 females (54.3%). The most and least frequent cases of stung were observed among individuals within the age range of 25-34 and 55-64 years, respectively. Hands, head, and face were the most prevalent sting sites with the occur-rence rates of 56.7, 37.8, and 5.5%, respectively. Scorpion stings occurred mostly during spring and summer with the highest rate of 30% in July. Out of total cases, 46.3% were residing in urban areas and 53.7% in rural areas. Conclusion: Considering the fact that the highest occurrence rate of scorpion sting was observed in rural areas, educa-tional programs for all health and medical personnel as well as physicians of centers, promotion of public aware-ness in the city and village, improvement of places and rural roads can play an important role in the prevention of scorpionism and mortality.


The title of this study is Material Process in Besemah Language Clause: A Functional Grammar Approach. It aimed to find out material processes in Besemah language and to analyze the elements of material processes found in the language. This research discusses three main points: (1) the verbs that can be categorized into material process; (2) the participants involved in the material process; and (3) the clause elements of material process. The approach applied in this study was Functional Grammar Approach (FGA) using descriptive method, employing data source from the book Bahasa Besemah 2, which were then analyzed by using tables to show the elements of material processes. The findings of the study showed that (1) the verbs ngelipat, belajagh, ngandas, ngadum, diagai, ngaduk, beghusiq , etc belong to the verbs of material process, (2) the participants involved in the material process can be actor, goal, recipient, client, range, and instrument, and (3) the circumstance can be place, time, manner, and purpose. The verb clause of material processes may be categorized into be intransitive, monotransitive, and ditransitive verb clause.


We introduce a class of rings, called Nash Rings, which generalize the notation of rings of Nash functions. Let k be any field, X be a normal algebraic variety in k ", and U C X. A Nash ring D is the algebraic closure of F(X, Qx) in a suitable domain B such that U is contained in the maximal spectrum of B and F( X, Qx) is analytically isomorphic to B at each x E U. We show that D is a ring of fractions of the integral closure of F( X, (9x) in B. Moreover, if k is algebraically nonclosed and if every algebraic subvariety V c X intersects U in a finite number of connected components (in the topology induced by B), then D is noetherian.


Based on the flight tests and subsequent studies of unmanned aerial vehicle(UAV),the opportunities and challenges of UAV in traffic information collection,processing and application were analyzed,and the application future of UAV in traffic planning and simulation,road surveillance,emergency dispatch,urban congestion analysis and so on was prospected.Analysis result shows that the traffic information collection method using UAV is effective for continuous traffic information collection and complements existing methods.Traffic information is automatically derived from UAV videos with the development of dynamic video processing technology.UAV traffic information can be used to study emergency responses,car-following,lane-changing behavior,traffic congestion and so on.However,the adaptability of UAV dynamic video processing technology needs to be improved.The research on car-following,lane-changing and traffic congestion using UAV information needs empirical testing.Some important research direction in the future includes the establishment of UAV-ground emergency communication and coordination system,and UAV-vehicle-road coordination communication system.4 figs,30 refs.


Today the telecommunication equipments are characterized by transmission bandwidths of tents of GHz. Consequently the digital signals into play reach data rates of some Gbps with rise/fall times of few picoseconds. In this context it is important to correctly characterize the transmission lines on boards for studying the signal propagation as a function of the frequency. The more effective technique starts from measurements, connecting the studied traces to the measurement instruments by means of transition networks or fixtures. But in this case the connective errors due to the connector mismatches and discontinuities have to be removed. The paper proposes different mathematical de- embedding procedures to evaluate the propagation constant of differential traces, de-embedded by the effects of the SMA's connecting them to the VNA.


The present invention relates to heater element, device provided therewith and method for manufacturing such heater element. The heater element comprises a heater of a resistance heating metal that is provided in, at or close to a fluid path configured for heating fluid, wherein the heater comprises a conductor that is provided with a porous ceramic layer. Preferably, the ceramic layer is provided on or at the conductor with plasma electrolytic oxidation. The ceramic layer has a preferred thickness in the range of 5-300 [mu]m, preferably 10-200 [mu]m, more preferably 50-150 [mu]m, and most preferably the thickness is about 100 [mu]m.


Ordinarily,teaching should involve two subjects:teacher and students.Instruction and learning should work together. The most important thing to improve the teaching quality is to practice Interactive teaching;the key to success in interactive teaching is to have a good teaching plan.Interactive teaching embodies the ideas of behaviourism,cognitivism and constructivism.Interactive teaching requires teachers to work student - orientedly,with modern teaching methods.


Digital marketing in social networks has attracted the attention of many entrepreneurs, especially those novice or inexperienced or responsible for small businesses, as they are more accessible, dynamic, comprehensive and low-cost means of communication. However, a problem that arises in this scenario is how, in practice, digital marketing has been developed by these entrepreneurs, often without training in the field, but eager for the visibility of less traditional media. The purpose of this article is to deepen the discussion about the impacts that marketing on social networks can cause in small companies, from the perspective of brand building, interactivity with their clients and profitability. The research is exploratory, with a qualitative approach, including inductive analysis, bibliographic review and two case studies carried out in small companies located in the cities of Guaruja and Guaratingueta (SP). The results of the research indicate that the strategy of investing in digital marketing through the main social networks is, in both cases, extremely efficient, viable and with few negative aspects.


TAKING advantage of cells for advanced clinical diagnosis is a long-standing aim in quantitative single cell sciences. For years, clinicians have realized that there is an urgent need for making cellular diagnosis (i.e., cytopathology and histopathology) reproducible, less influenced by the level of experience of the human observer and less time consuming. However, it turns out that it is long and stony road to make computers understand what cells and subcellular compartments are in a grey scale or in a color image. This year's special issue on "Computer-aided Diagnostics in Digital Pathology" guest edited by Bengtsson et al. (1) further focused on innovations in this area. Recently, computational approaches like deep learning became popular for identifying and quantifying biological structures in tissues as investigated for breast cancer (2). These approaches harbor the promise to strengthen reproducibility in cellular diagnostics (3). The present issue contains several articles addressing clinical questions to be answered by the cells and their images using computing methods to increase reliability. The important thing about these articles is that they are jointly authored by practitioners (physiologists) from specific clinical areas, basic scientists and information scientists, demonstrating how essential collaboration between specialists is herein. Among these collaborations is the work by Bombrun and colleagues (this issue, page 1068), highlighted by a Commentary from Doan (this issue, page 1051), and was selected by me as one of two Editor's Choice articles of the month. Here, the authors demonstrate a new high-content analysis approach to identify and quantitate lipid droplets that play an important role in adipogenesis in health and disease. Peikari and colleagues (this issue, page 1078) developed an automated method to analyze material from surgical breast tumors and determine their cellularity. This parameter is of high relevance for clinical decision making in breast cancer. The new method that works with whole slide images has a comparable performance to pathology experts when tested on real-world specimens, but clearly reduces their workload. Do and colleagues (this issue, page 1088) used Imaging Flow Cytometry to visualize chromosomal deletions and cell sorting for further molecular biological analysis. Here, the combination of (flow) imaging that led to improved detection and isolation, and is of high relevance for applying individualized therapy. Finally, the second Editor's Choice is by Leers and colleagues (this issue, page 1059). They investigated the relevance of the major subgroups of circulating monocytes in different types of coronary heart diseases. Although they applied slightly different gating approaches to identify classical, nonclassical and intermediate monocytes than described in an earlier article by Zawada et al. (4), they could confirm previous findings on the correlation of coronary heart disease monocyte subset abundance. However, this study goes beyond and shows the correlates of antigen expression and NSTEMI


Thank you very much for downloading design evaluation and translation of nursing interventions. As you may know, people have look hundreds times for their chosen novels like this design evaluation and translation of nursing interventions, but end up in malicious downloads. Rather than enjoying a good book with a cup of tea in the afternoon, instead they juggled with some harmful virus inside their computer.


Using results from the theory of abstract frames, an algorithm is given for the recovery of band-limited signals from samples taken at nonuniformly spaced points. The algorithm converges geometrically and globally, and it has important robustness properties. >


Surface sensitive techniques – Auger electron, X-ray photoelectron and high resolution electron energy loss spectroscopies (AES, XPS, HREELS), low energy ion scattering (LEIS), reflection absorption infrared spectrosocpy (RAIRS), low energy electron diffraction (LEED) – were used to study adsorption of submonolayer films of Ti, Fe, Ni, Ag, Au on the surface of aluminium, magnesium and titanium oxide films in-situ grown on the Mo(110) support. Separated metal atoms and small clusters, deposited on oxide supports, acquire cationic character, presumably due to interaction with surface defects. As the defects are being covered with increasing of the surface concentration of metal atoms, their effect decreases, so the interface charge transfer effect weakens, further accompanied by lateral depolarization of adatoms at higher coverage. Choosing atomic structure, morphology, relative content and nature of supported metal/oxide structures allows precise tuning of their electronic, catalytic and optical properties crucial, for new technological applications.


Background: Magnetic resonance imaging is a very useful diagnostic tool for the detection of abnormalities of injured knee joint.
Objective: This present study was performed to see the different abnormalities of injured knee joint detected by MRI among adult patients.
Methodology: This cross-sectional study was conducted in the Department of Radiology and Imaging at Bangabandhu Sheikh Mujib Medical University (BSSMU), Dhaka, Bangladesh from January to June 2021 for a period of six months. The patients in the age group of equal or more than 18 years with both male and female who were visiting Department of Orthopaedics at BSMMU, Dhaka with history of knee injuries were subjected to MRI were selected as study population. MRI findings of the knee joint were analyzed for the presence of any signal changes or lesions of varying severity for the structures of menisci, cartilage, bone marrow, tendons and ligaments of injured knee joint.
Results: A total number of 65 cases of knee joints were analyzed. The mean with the SD of age of the study population was 35.34±13.371. The left knee (60.0%) was more involved than right knee (40.0%). The lesion in femur and tibia were found in 10(15.4%) cases and 8(12.3%) cases respectively. Out of 65 knee joints there were 41 joints were found the tear of anterior cruciate ligament. The complete, interstial tear in the anterior cruciate ligaments were 26(40.0%) and 15(23.1%) knee joints respectively. However, anterior cruciate ligaments of 24(36.9%) knee joints were found normal. Medial meniscus (36.9%) was more involved than lateral meniscus (18.5%).
Conclusion: In conclusion young adult male are more commonly affected their left knee joint with the tearing of complete tear of anterior cruciate ligaments and involvement of medial meniscus.
Journal of Current and Advance Medical Research, July 2021;8(2):80-84


Robust and efficient synchronizers are keys elements to ensure good gear shift in heavy vehicles. In order to improve existing as well as develop new synchronizers, efficient simulation tools are needed. In this contribution, a mechanical system with 5 degrees of freedom modelling a generic synchronizer consisting of engaging sleeve, synchronizer ring and gearwheel are considered.
Due to the design of the different components and their interactions the synchronizing process is described in terms of different steps or phases; presynchronization, main synchronization, blocker transition and engagement. The four main phases are further divided into sub-phases.
To study the whole process in a unified manner, Constrained Lagrangian Formalism (CLF) turns out to be a suitable method in which the interactions between components (sleeve,
synchronizer ring and gearwheel) are described by unilateral or/and bilateral constraints imposed on generalized coordinates of the system during different phases. Using CLF a mathematical model of a generic synchronizer is developed and represented by the system of differential-algebraic equations. Kinematics and kinetics of the generic synchronizer are modelled for each sub-phase. The sleeve is considered as a master and the
gearwheel is considered as a slave. The statement of the dynamics problem for a generic synchronizer is given and the numerical algorithm is implemented in Matlab for solving the differential-algebraic equations resulting from CLF. The generic synchronizer computational model is adapted to available experimental setup and validated using obtained measurement data. Sensitivity of the synchronization time is studied varying the cone angle, coefficient of dry friction and sleeve force. Effect of driveline vibrations on synchronization performance is
also studied.


In this paper we use the penalty approach in order to study constrained minimization problems in infinite-dimensional Asplund spaces with nonsmooth nonconvex mixed constraints. A penalty function is said to have the exact penalty property if there is a penalty coefficient for which a solution of an unconstrained penalized problem is a solution of the corresponding constrained problem. In this paper we establish sufficient conditions for the exact penalty properties using the notion of the Mordukhovich basic subdifferential.


effects of ammonia-resistant type klebsiella oxytoca on cucumber were studied. It was showed that disposing seeds with application 5 percent liquid type of N_2-fixing bacteria, spraying leaves and pouring root with application0.5 percent liquid type after transplantation l day and 20 days significantly enhanced the seeds budding, seedling growth, plot yield and fruit quality in cucumber. It had the same effect with application powder type of N_2-fixing bacteria, but no more remarkable than liquid type.


[Objective] To discuss the application of early endoscopic realignment in treatment of urethral disruption.[Methods] Six cases of urethral disruption were reviewed which were managed by early ureteroscopy realignment.[Results] Five of 6 cases were done in retrograde approach,and one in retrograde/antegrade approach,all having succeeded,follow-up done at 2 months ~ 4 years post-opeatively,all with e good uroflow,but 4 of 6 cases developing urethral stricture.[Conclusion] Early endoscopic realignment is an efficacious and safe option for treatment of urethral disruption.


Cushing's disease is the most common cause of endogenous Cushing's syndrome caused by the excessive secretion of adrenocorticotropic hormone (ACTH) by pituitary ACTH-secreting tumors. The tumors are usually microadenomas (< 10 mm in diameter). Macroadenomas are rare, and corticotroph hyperplasia and carcinomas are extremely rare. Patients with these tumors exhibit an increase in plasma ACTH and cortisol levels, elevated urinary excretion of cortisol and adrenocortical steroid metabolites, evidence of altered negative feedback of cortisol and disturbances in neuroendocrine regulation. The diagnosis of Cushing's disease can be challenging in patients with renal failure the presence of abnormal plasma cortisol, poor gastrointestinal tract absorption of dexamethasone and altered functioning of the hypophyseal-pituitary-adrenal axis have been reported in end-stage renal disease, and the urinary cortisol increment method is not reliable in these patients. The prevalence of renal cell carcinoma in patients on dialysis is higher than in the general population. We recently treated a patient with Cushing's disease and end-stage renal disease as a result of renal cell carcinoma. The diagnosis was made by laboratory evaluation of plasma and radiological examination. Here we report a case of Cushing's disease with a review of the medical literature. (J Kor Endocrinol Soc 22:62~67, 2007)


In many modern optical systems, the resolution is limited not only by the diffraction caused by physical dimensions of the optics lens, but also by the CCD's nonzero pixel size. Especially for the traditional incoherent illumination, the restriction of CCD pixel is greater than that of optical diffraction. Here we develop a novel approach to enhancing resolution beyond the limit set by CCD's pixels, in which a two-dimensional and orthogonal encoding mask is attached before the imaging lens to modulate frequency on input target spectrum. Here we focus on the design about a 4f optical imaging system, considering the ability of Fourier transformation to achieve the equivalent conversion between space and frequency domain. And to prevent the loss of frequency in the overlapping regions when sampled by classical CCD, there must be some proportion between the spatial range of object plane and corresponding frequency plane. Meaning while, the wavefront aberration of Fourier lens needs to be controlled to fulfill the mathematical features of Fourier transformation. We apply to improving and revising the theoretical design for the encoding mask based on the design limit of opticalmechanical engineering, and we analyze the different orthogonal forms of encoding masks which can bring the spectra diffraction to the imaging area. According to the theoretical discussion, revision and algorithm simulation, the results in the preliminary testing system show that the encoding mask can be used to produce enhancement of resolution by a factor of 2 in-exchange for decreasing the field of view by the same factor.


The US is often taken to be a contrary case to the general decline of religion in the West. David Voas and Mark Chaves find that religiosity is in fact decreasing in the US, and for the same reason that it has been falling elsewhere. They comment that Americans are not becoming less religious over their lives; rather, the more religious generations born in the early 20th century are dying off and being replaced by newer generations that are less likely to be religious.


: For the nozzle steam turbine , the combined flow characteristics calculation model of governing valve and governing stage is established by calculation, and tested with open literature experimental data. The accurate flow of the governing valve can be calculated with the model by using the combination pressure ratio and the valve opening, which is convenient for engineering application. Method a calculation model for the off-design performance of a 300 MW steam turbine unit based on the combined valve model, and the valve distribution function is optimized, and the flow character of the sequential valve is obtained. Then the steam distribution optimization is analyzed by using the load and valve position. Analysis shows that the combined flow characteristics calculation model of governing valve and governing stage can reflect the characteristics of the valve accurately. According to the model, the flow characteristic is optimized, the reasonable overlap degree is obtained. The optimal slip pressure curve of the unit is obtained, which reduce the heat consumption during low-load operation of the unit and improves the flexibility and peak-regulating capacity of the unit and provides the theoretical basis for optimization test.


A good suite of test inputs is an indispensable tool both for manual and automated assessment of student submissions to programming assignments. Yet, without a way to evaluate our test suites, it is difficult to know how well we are doing, much less improve our practice. We present a technique for evaluating a hand-generated test suite by comparing its ability to find defects against that of a test suite generated automatically using Constraint Logic Programming (CLP). We describe our technique and present a case study using student submissions for an assignment from a second-year programming course. Our results show that a CLP-generated test suite was able to identify significant defects that the instructor-generated suite missed, despite having similar code coverage.