Lump solid fuel is one of the most important charge material components in layered cupola units. It determines layer gas permeability, conditions development for heat exchange with gasses in it, heat generation process rate and intensity. In present-day conditions of material shaft melting charge materials of boosted fractional makeup are used, as well as oxygen, carbon and hydrogen enriched air. In the circumstances the issue of ensuring the best gas dynamic conditions become particularly vital, both for the furnace low and high temperature zones, at the charge component oxidation and recovery processes development. Under conditions of continuous charge component movement in the layered unit workspace they are subjected to abrasive action of charge components with the result, which may be described by mechanical properties based on mass yield of certain fractions after disruption in a closed drum М10 and М40. Coke lump behavior at relatively high temperature (below 1100°С) in the presence of complete fuel combustion products СО2 and Н2О may be implicitly evaluated by coke strength after reaction (CSR) and coke reactivity index (CRI). When studying, particular combustion features of coal coke in conditions close to shaft cupola unit operation data of the total differential scanning calorimetry (DSC) curve were used. Temperature ranges of intensive heat generation were determined from the beginning of active coke sample oxidation to completion of the burnout period, as well as apparent heating capacity and coke combustion thermal effect.


An intelligent home scene control method comprises the steps of starting a terminal equipment registering mode according to a terminal equipment registering request from an input unit to register registering information of terminal equipment in the current scene and starting a terminal equipment status reading mode according to a terminal equipment status reading request from the input unit to read and store work status information of the terminal equipment in the current scene. The input unit of a scene controller can be simply operated to generate corresponding requests, namely an intelligent home system can be in corresponding work modes. A user only needs to simply operate the terminal equipment needing to be added, so that the system can automatically store the registering information of the terminal equipment. The system can automatically read and store work status information of the corresponding terminal equipment. A user can simply set and control scenes without having basic computer knowledge. The invention further relates to the intelligent home scene control system and the scene controller.


To satisfy the requirement of serial communication in hardware-in-loop simulation,the serial communication technology using circular buffers driven by the CPU interrupt and the software timing in xPC target was proposed.The key technologies based on the S-function were studied which included the module task principle analysis,hardware interrupts obtain,the circular buffer design and its parameter transmission,and the write and read of the buffer.The communication module of the inertial measurement unit was achieved using this method,and test on the three axis simulator,which can get the acceleration and angular rate information correctly.Tests prove that the proposed method is effective and can help the expansion of the xPC target.


ABSTRACT Organic amendments are essential to the sustainability of soils, as they help maintain the soil's physical and chemical properties. But, when applied in large dosage amounts, these amendments can drastically change the soil gas composition and have detrimental effects on plant roots and the microbial population. For 208 h, the present study monitored the O2 deficit and loads of CO2 and NH3 in 750 mm deep sand columns, after applying cattle manure at rates equivalent to 0, 20, 40 and 80 tons/ha, within a layer at a depth of 150 mm to 250 mm. Also, a first order model using a manure biological oxygen demand (BOD) reaction rate coefficient k1 and a soil re-aeration rate k2 were used to model the O2 deficit occurring over time in the soil columns. The results indicated that all three gases demonstrated a peak O2 deficit, and loads of CO2 and NH3 after 16 h of manure application and in proportion with the rate of manure application. These peaks dropped quickly during the next 24 h, followed by a steady state up to 168 h and then a gradual loss of gas deficit and loads thereafter. This indicated that the manure/soil layer, at a depth of 150 mm to 250 mm, started to loose its permeability, 24 h after applying the manure. The first order model adequately simulated the soil column O2 deficit and loads of CO2 and NH3, as long as the value of the re-aeration rate k2 drops exponentially with time, as of 24 h. More research work is required to be able to predict the manure/soil gas permeability and its effect on the soil's gaseous regime.


In this study, some short questions are asked and answered in order to give important information about Passive Seismic Monitoring Methods (P3M) using the Kipling method. P3M contain powerful tools which are detecting, analysing and interpreting of the microseismic events. Today those methods have an increasing usage in the worldwide. Most of them are in mining sites, oil and gas sites, geothermal sites and also hydraulic fracturing sites.


Purpose: The present research aims at checking the social environmental practices carried out by the B corps, as well as the advantages and challenges faced by the movement. Design/methodology/approach: The research is descriptive and qualitative, carried out through multiple case studies with 11 Brazilian companies certified by the B Lab. The sources of data collection were semi-structured interviews with owners, managers, or employees who were actively engaged with sustainability causes in the company, in addition to the use of documents. Data were analyzed through content analysis.Findings: The main results showed that the B Corps works to resolve either social or environmental problems, even if their core activity is not for this purpose. Among the advantages of being part of the movement is the strength of working in a group with the same purpose, in search of transforming the capitalist market and recognizing its practices. The challenges in the certification search are related to the formalization of practices, considering that they are mostly small companies and the need for greater dissemination of the movement.Originality/value: The study contributes both to the advance in the literature regarding the understanding of the B Corp movement and to the evolution of the concept of hybrid organizations. As empirical contributions, the research serves as a basis for people and companies that seek to alleviate social and environmental problems through their practices and professional activities.


8 ASUBTITLE: WHILE IMO IS NOT SET TO AGREE TO AN EXHAUST EMISSIONS ANNEX TO MARPOL UNTIL MID-1994, CONSULTING ENGINEERS ARE READY NOW WITH PROVEN SOLUTIONS.


Improved synthesis, charge carrier mobility, conformation, crystalline structure, and molecular packing of the regiochemically pure 4',3' '' '-dihexyl-2,2';5',2' ';5' ',2' '';5' '',2' '' ';5' '' ',2' '' ''-sexithiophene (β,β'-DH6T) are reported. The sum of charge carrier mobilities of β,β'-DH6T measured by the pulse-radiolysis time-resolved microwave conductivity (PR-TRMC) technique was found to be ∑μmin = 3.9 × 10-3 cm2 V-1 s-1, which is comparable with the PR-TRMC mobility found for α,ω-DH6T. The field-effect mobility (FEM) of β,β'-DH6T was found to be on the order of 10-5 cm2 V-1 s-1, which is considerably less than the FEM of α,ω-DH6T. To understand the reason for such poor macroscopic electrical properties, the conformation and the molecular packing of β,β'-DH6T were systematically studied by means of UV−vis spectroscopy, scanning electron microscopy (SEM), atomic force microscopy (AFM), and X-ray techniques. Absorption spectra of a β,β'-DH6T spin-cast film indicate the planar conformation of the aro...


Significance Radioimmunotherapy is predicated on harnessing the exquisite specificity of antibodies to deliver cytotoxic radiation to tumors. Yet the long circulation time of radioimmunoconjugates leads to high radiation doses to healthy tissues. Pretargeted radioimmunotherapy (PRIT) circumvents this problem by decoupling the antibody and radionuclide, injecting the former prior to the latter, and empowering the two components to combine at the tumor. We have leveraged bioorthogonal click chemistry, a colorectal cancer-targeting antibody, and a pair radioligands bearing radioisotopes of copper—positron-emitting copper-64 and beta particle-emitting copper-67—to create a pretargeting system that enables both theranostic positron emission tomography and PRIT. We believe that the incorporation of theranostic imaging into PRIT regimens could be instrumental in the clinical success of the modality. Over the past decade, theranostic imaging has emerged as a powerful clinical tool in oncology for identifying patients likely to respond to targeted therapies and for monitoring the response of patients to treatment. Herein, we report a theranostic approach to pretargeted radioimmunotherapy (PRIT) based on a pair of radioisotopes of copper: positron-emitting copper-64 (64Cu, t1/2 = 12.7 h) and beta particle-emitting copper-67 (67Cu, t1/2 = 61.8 h). This strategy is predicated on the in vivo ligation between a trans-cyclooctene (TCO)-bearing antibody and a tetrazine (Tz)-based radioligand via the rapid and bioorthogonal inverse electron-demand Diels–Alder reaction. Longitudinal therapy studies were conducted in a murine model of human colorectal carcinoma using an immunoconjugate of the huA33 antibody modified with TCO (huA33-TCO) and a 67Cu-labeled Tz radioligand ([67Cu]Cu-MeCOSar-Tz). The injection of huA33-TCO followed 72 h later by the administration of 18.5, 37.0, or 55.5 MBq of [67Cu]Cu-MeCOSar-Tz produced a dose-dependent therapeutic response, with the median survival time increasing from 68 d for the lowest dose to >200 d for the highest. Furthermore, we observed that mice that received the highest dose of [67Cu]Cu-MeCOSar-Tz in a fractionated manner exhibited improved hematological values without sacrificing therapeutic efficacy. Dual radionuclide experiments in which a single administration of huA33-TCO was followed by separate injections of [64Cu]Cu-MeCOSar-Tz and [67Cu]Cu-MeCOSar-Tz revealed that the positron emission tomography images produced by the former accurately predicted the efficacy of the latter. In these experiments, a correlation was observed between the tumoral uptake of [64Cu]Cu-MeCOSar-Tz and the subsequent therapeutic response to [67Cu]Cu-MeCOSar-Tz.


Planar optical elements with efficient light control at the nanoscale can be designed based on transdimensional photonic lattices that include 3D-engineered nanoantennas supporting multipole Mie resonances and arranged in the 2D arrays to harness collective effects in the nanostructure. Periodic arrays of nanoparticles have gained special attention because of extraordinary lattice resonances in proximity to the wavelength of diffraction, the so-called wavelength of Rayleigh anomaly. We show the possibility of exciting strong periodic nanoparticle resonances not only in plasmonic arrays but also in the nanoparticle lattices with the high refractive index. We perform the calculation for tungsten disulfides, which belongs to the families of van der Waals materials and transition metal dichalcogenides. Nanoparticles arrangement in a periodic array plays a crucial role resulting in collective array resonances and pronounces features in spectra.


In Section III of her seminal if controversial reading of Walter Benjamin, Hannah Arendt rightfully remarks upon Benjamin's engagement with what she diagnoses, here and elsewhere in her works, as a certain Traditionsbruch, or "break in tradition." She reminds her readers that, insofar as "the past has been transmitted as tradition, it possesses authority," and to the extent that "authority presents itself historically, it becomes tradition." Benjamin, Arendt suggests, "knew that the break in tradition and the loss of authority which occurred in his lifetime were irreparable," propelling him "to discover new ways of dealing with the past." According to Arendt's account, if Benjamin's trademark insight is "that the transmissibility of the past had been replaced by its citability and that in place of its authority there had arisen a strange power to settle down, piecemeal, in the present," then his new way of organizing the past is to quote it in ever-renewed and reconceptualized constellations, rather than seeking to "repair" a broken tradition by reinserting the past into it.1 Next to the practice of citation, Arendt trains her focus on Benjamin's privileging of the figure of the collector in response to the Traditionsbruch in modernity. The


Circular 1517, a 15-page full-color catalog compiled by Mechelle N. Best and Taylor V. Stein, provides case studies of ten private nature-based tourism businesses throughout Florida. Each case study provides a brief description of the site, presents the start-up and operational challenges encountered, and highlights the lessons learned by the various owners/operators. Finally, the benefits to the owner/manager and the reasons why they stick with it are provided. Published by the UF School of Forest Resources and Conservation, September 2007.
CIR 1517/FR178: Nature-Based Tourism in Florida: Letting Nature Work for You (ufl.edu)


To Introduce the mechanism of ototoxicity caused by aminoglycoside antibiotics. To review the data about effectiveness of Traditional Chinese Medicines in treating ototoxicity of aminoglycoside antibiotics. Were Summarized and analyzed 10 kinds of herb(Ligusticum chuanxiong Hort., Radix Salviae Miltiorrhizae, Eleu-therococcus senticosus (Ruper.et Maxim.), Radix Angelica, Radix Scutellariae,Pueraria lobata(Willd.), Poria cocos(Schw.) Wolf, Rhizoma Drynariae, catechin, Oenothera erythrosepala Borb.) and a variety of compound (Fucong tablet, Erlong zuoci pill, Jinkui Shenqi Pill, Tiangu Granule, Fufang Danshen tablet, Bushen Cong-er tablet, etc.), Their effectiveness on treating experimental ototoxicity of aminoglycosides antibiotics as well as their possible mechanisms.


At the present time Federal Reserve policy-making may be viewed as having a two-part structure. First, based on a four to eight quarter economic forecast, the Fed selects a target rate of money growth. Second, based on a short-term money market forecast, the Fed selects a Federal funds rate range thought to be consistent with the money growth target. The procedure followed in selecting the money growth target is "state-of-the-art" but the policy implementation based on controlling the Federal funds rate has permitted an undesirable pro-cyclical behavior of the money stock.


precursors RNA proteins delayed implantation. These exceriments reveal the absence of labeled thymine incorpo- ration by diapausing blastocysts from mink, fur seal, and lactating rat, although thymine is incorporated by nondiapausing


The 'Desert' society in Cevennes, Languedoc, was an offshoot of the persecution of French Protestants by Louis XIV. The clandestine assemblies that met in the ravines gave rise to lay ministry, as the Revocation of the Edict of Nantes (1685) had forced profes sional ministers to flee abroad. At first, Predicants replaced ministers, then Prophets and Prophetesses in turn replaced the killed Predicants. The 'Desert' society gave birth to a popular culture. At the end of the seventeenth century, the Protestants' resistance was peaceful, but as persecutions grew, the Camisard war broke out in 1702. But a minority of Prophets refused violence, even in self-defence, as a solution to the Protestants' problems. They gathered in the Vaunage valley, around Congenies, near Nimes. Their spiritual descendants met British Friends in 1785, and joined the Religious Society of Friends in 1788. They also belonged to the popular culture of the 'Desert' society.


Usually only one degradation channel is considered in ordinarily accelerated degradation analysis.But actually Multi-degradation mode is existed. The relation of every degradation channel of the product may is random,each relation channel can't be only interrelated or independent.Considering of this relativity,the paper makes scientific researches on electronic equipments performance degradation theory and mechanism,gives an electronic equipments reliability evaluation model in multicenter instance,and an competition invalidation model under multi-mode interrelated.


Bard's work focuses on how membrane trafficking regulates protein glycosylation and other cellular functions.

At the age of seven, Frederic Bard's father taught him about the atomic composition of water molecules. Bard was flabbergasted to learn that water is not simply "made of water." He


The history of research into the pathobiology and treatment of PNH is beautifully reviewed by Dr. Charles Parker in the keynote paper of this education session. What is remarkable about studies of this disorder is that insights into the causality and manifestations of PNH drew upon new basic science advances that were reported at the American Society of Hematology (ASH), or discovered and clarified by leading figures in the development of ASH. Many of these contributors were not studying PNH but turned their attention to it because its distinctive features offered end points to test their hypotheses. PNH is an example of the unique contributions that the study of (often rare) hematologic disorders has made to the advance of biomedical research. Appreciation of new biologic phenomena, such as the alternative pathway of complement activa-tion or the role of clonality in proliferative disorders, were shown to be relevant to human diseases by study of rare but distinctive blood disorders like PNH. Given this proof of principle, others become inspired to adapt the same approaches to more common diseases as technological progress permitted. As described in Dr. Parker's review, extraordinarily insightful research in Europe had established that PNH was a distinct form of intermittent intravascular hemolysis by the mid 1940s; moreover, the key insight that a subpopulation of red cells were hypersensitive to lysis in acid had been made and the classic Ham test developed by the time that ASH was founded in 1958. What was missing was an understanding of the mechanism causing hypersensitivity. The classic complement pathway did not seem to be the key. PNH thus became one reason to predict the existence of an alternative pathway; this prediction, of course, turned out to be true. This linked the study of this disorder to the rapidly improving descriptions of immune mechanisms that highlighted the very first ASH meetings. The rest, as noted by Parker, is history. The mosaicism of PNH cell populations with regard to lytic sensitivity, the evolution of methods to measure complement components on cells, the elucidation of the metabolic networks of the alternative pathway, the elucidation of the impor-tance of anchored membrane proteins in modulating biochemical


Ab initio molecular dynamics (aiMD) is the computational technique to investigate the dynamics of solids at high temperatures, at which perturbative harmonic approximations break down. Determining accurate thermal transport coefficients from aiMD has so far remained elusive both due to conceptual and numerical challenges. In this work, we overcome these limitations by evaluating the auto-correlation function of the heat flux using the Green-Kubo formalism [1]. In this talk, we discuss the fundamental theory underlying a first-principles definition of the heat flux using the virial theorem. We demonstrate and validate our approach by inspecting silicon, the thermal conductivity of which is particularly challenging to converge [2]. Furthermore, we investigate the thermal conductivity of ZrO2, which is known for its high degree of anharmonicity and important role for thermal barrier systems. Our calculations shed light on the peculiar mechanism active in this material, which eventually allows us to discuss how to control it by doping and co-doping [3].


SUMMARY It is important to identify the factors that increase the utilization rate and demand of improved seed; an informed choice by the corn (Zea mays L.) grower could turn into gains of productivity and welfare. A logit model provided the answer to this question. The logit model considered the logit of the probability ratio of improved seed use against alternative seed use as the dependent variable and production units size, income, improved seed price, fertilizers price and pesticide price as the independent variables. Results indicated that a 10 % increase in production unit size and income per hectare results in increased demand and probability of improved seed by 3.8 and 1.7 %, respectively. A 10 % decrease in the price of improved seed increases demand and probability of improved seed use by 3.7 %. A simultaneous 10 % in prices for improved seed, fertilizer and pesticides results in a 17.5 % increased probability of using improved seed. These results highlight the significant effect agricultural inputs possess on improved seed use and, therefore, in productivity.


Hospitalization Bureau Portal being a part of Unified National Health System enables patients to have free choice of medical organization and medical services.


People living in rural areas are having traditional health care practices which are valuable knowledge for maintain human health and animal health, hence present investigation has been made to document the Traditional veterinary health care knowledge of local communities in Jagalur Taluk of Davangere district, Karnataka. The present study revealed that, a total of 121 medicinal plant species belongs to 117 genera and 54 families used for animal health care. The 40 different ailment types were documented as veterinary health problems in study area. The major and most widespread diseases according to the informants include 14 plant species were used for the treatment of bloat disease, 14 plants for fever, 12 plants for dysentery, 10 plants for lack of appetite and 9 plants for foot and mouth disease, 7 species for bone fracture and dislocation of bones. Of the 121 recorded plant species frequently applied plant species against veterinary ailments. Proper documentation of this type of indigenous knowledge about the plants could be supportive in achievement of sustainable threatened of endangered medicinal herbs and conservation aspect with future research.


I ran is among the largest countries in the Middle East. This region includes parts of West Asia and North Africa and is the centre of the Islamic world, with over 300 million Muslims. Iran has many ethnic groups, including Fars, Turks, Kurds, Gilaks, Lors and Baluchis. Iran is an important country in world medical history, but exact dates in its medical history are unclear. Babylonian medicine began about 6000 years ago, nearly 4000 years before Greek medicine emerged. Babylonian society was essentially polytheistic.


The memristor, known as the fourth basic two-terminal circuit element, has attracted many research interests since the first real device was developed by HP labs in 2008. The nano-scale memristive device has the potential to construct some novel computing systems because of its distinctive characters, such as non-volatility, non-linearity, low-power, and good scalability. These electrical characteristics of memristors are mainly determined by the material characteristic and the fabrication process. For example, process variations may cause the deviation of the actual electrical behavior of memristors from the original design and result in the malfunction of the device. Therefore, it is very important to understand and characterize the impact of process variations on the electrical behaviors of the memristor and its implication to the circuit design. In this paper, we analyze the impact of the geometry variations on the electrical characteristics of the memristor. Two parameters — NARD (Normalized Accumulative Resistance Deviation) and NAARD (Normalized Accumulative Absolute Resistance Deviation), are introduced to measure the fluctuation of the overall internal state (or the resistance) of a memristor under the impact of process variations. Based on our analysis, Monte-Carlo simulations are conducted to evaluate the device mismatch effects in the memristor-based memory.


A cooperative research effort was performed on one Fruitland coal gas well with AMAX Oil and Gas Inc. The well is located along the western margin of the San Juan basin where both hydraulic fracture and openhole cavity completion techniques have been used. The objective of the research effort was to: (1) determine the reservoir characteristics (gas content, sorption isotherm, absolute permeability, and reservoir pressure) of a shallow Fruitland coal interval, (2) evaluate the effectiveness of the openhole cavity completion technique in the reservoir, and (3) compare the results of this openhole cavity completed well to offset hydraulic fracture completed wells.


The semantic web initiative of the world-wide web consortium (w3c) has been active for the last few years and has attracted interest and skepticism in equal measure. Semantic search generally deals with the searching of the keyword along with the concept related to that semantic word. Perhaps the most widely developed space at the moment within the semantic web is in information management, i.e. the organization and discovery of information. This is the primary motivation behind the semantic web's development, but people are taking a variety of approaches to developing tools to extend the current web into a true semantic web. One of the methods of implementing semantic search is by means of agents like indexing agent, query agent and ontology agent. Index agent downloads files from web and extract textual content, query agent process all queries, ontology agent extracts the descriptive concepts and calculates relation between those concepts. The main problem with these agents is the pages retrieved after searching are not relevant. The other method of implementing semantic search is by combining semantic search and ontology learning. The need for domain ontology for information retrieval to improve answer queries, However ontology in information retrieval systems requires regular updates and relationship between new concepts. Semantic search and ontology collectively improves the value of indexing documents and enriching ontology. It is done by multi layer like domain ontology,topic ontology, and natural language ontology. The main constraint here is this system is based on little domain ontology that cannot be expanded. Semantic search is also implemented by improving results with light weight semantic search. Here search queries and light weight semantics are combined together to improve search results. It is done by basic and concept scoring computation. Here indexing is done allocating resources and results are obtained by means of search engines. The main problems in this research are the inverted resources and metadata are not allocated properly for indexing. The problems with the previous implementations are time complexity, accuracy in retrieving pages, domain ontology,and resource allocation for indexing. The semantic pages are searched in the query repository based upon the algorithm for query retrieval. Then an algorithm for ontology based search is implemented. The ontology is obtained based on multi level ontology structure. Then a retrieval algorithm is designed to implement the semantic search.


In order to define the relationship between treatment‐induced changes in diabetic control and improvement in in vivo insulin‐stimulated glucose utilization (insulin clamp technique), 30 patients with non‐insulin‐dependent diabetes mellitus (NIDDM) were treated with either insulin, glipizide or diet alone, depending on their initial weight. Fasting plasma glucose concentrations fell from 16.3±1.2, 15.9±1.0, and 16.3±1.0 mmol/l, (mean ±SE) to 6.3±0.5, 11.6±0.6, and 13.4±1.6 mmol/l, after insulin, glipizide and weight reduction, respectively. These changes in fasting plasma glucose concentration were associated with an improvement in insulin‐stimulated glucose uptake, which increased by 69% after insulin, 45% after glipizide, and 72% after weight reduction. Thus, the improvement in insulin action was comparable in the three different groups of patients following each therapeutic intervention, and appeared to be unrelated to the fall in plasma glucose concentration. These results appear to suggest that the ability of any specific treatment to improve diabetic control can vary independently of its effect on in vivo insulin‐stimulated glucose utilization.


Trypanosomes and Leishmania, the causative agents of African sleeping sickness, Chagas disease, and Leishmaniasis, are responsible for over half a million human deaths per year in subtropical and tropical regions around the world. Only a handful of chemotherapeutics are available, and their efficacy suffers from drug resistance and serious side-effects. Therefore, new inhibiting compounds of essential targets are urgently needed. Trypanosomes lack both glutathione reductase and thioredoxin reductase, but possess the phylogenetically related trypanothione reductase (TR), a validated drug target and key enzyme of the unique trypanothione-based thiol metabolism. By inhibiting this essential flavoenzyme the parasite becomes vulnerable against oxidative stress induced by the host defense system and drug treatment. Here, we provide an overview of published TR screenings, and present an alternative approach combining in silico and in vitro experiments. Starting from an in vitro screen of 2816 highly diverse compounds, 21 novel TR actives could be identified. These inhibitors were used as the starting point to identify similar substances within a compound library of 200 000 available chemicals by a ligand-based in silico screening. In vitro screening of the resulted in silico-enriched dataset led to the identification of 61 additional TR actives. All 82 TR inhibitors showed IC50 values down to the nanomolar range. Subsequently, the dataset of known actives was used to implement a novel structure-based in silico screening approach that might identify further potential novel TR inhibitors.


With the development of science and technology, laptop becomes very popular. Laptop manufacturing firms are concerning how much spare parts they shall prepare to meet the demand of repairing. The quantities of spare parts are not only related to laptop life time, but also concern with users' repair willingness. We propose an approach to calculate the repair probability of laptop parts combined Poisson Process with users' repair willingness. In this study, the users' repair willingness relates laptop parts failure frequency. The new approach's verification is carried on by simulation. The significant test results show that simulation data fit theoretical value very well. By survey data and simulation result, we find that after four times broken for a laptop, a user will give up repairing it. The calculation result of new approach shows that spare parts quantities are entirely lower than traditional theory. From this point, if laptop manufacturers know their each parts lifetime, with the help of this paper, they can cut down their spare parts and save their service costs reasonable than before. (Received, processed and accepted by the Chinese Representative Office.)


This article investigates the extent to which options on the Australian Stock Price Index can be explained by parametric and nonparametric option pricing techniques. In particular, comparisons are made of out-of-sample option pricing performance and hedging performance. The dataset differs from many of those used previously in the empirical options pricing literature in that it consists of American options. In addition, a broader spectrum of techniques are considered: a spline-based nonparametric technique is considered in addition to the standard kernel techniques, while the performance of a Heston stochastic volatility model is also considered. Although some evidence is found of superior performance by nonparametric techniques for in-sample pricing, the parametric methods exhibit a markedly better ability to explain future prices and show superior hedging performance. , .


A digital caliper with force-measuring display disc belongs to a measurement instrument, which is mainly composed of a digital assembly, a force gauge, and mechanical parts. The caliper body is slidably connected with the caliper frame in the mechanical parts, the disc is connected to the caliper body and the lower claw of the caliper frame, a mounting board is connected with the right lower end of the caliper frame by welding, and a spring leaf is connected to the right lower end of the caliper frame by screws. The digital assembly is connected to the front side of the caliper frame, the force gauge is connected to the mounting board by screws, and the gauge head of the force gauge is relative to the spring leaf. The utility model can display the measured force visibly with high measurement accuracy, which can be used for accurately measuring the object length or thickness with strict standard on the force measurement.


Granular materials display a certain number of properties that have long been observed but only partially understood. Some resemble the properties of solids, some resemble the properties of fluids and others are unique. The concept on "fourth state of matter" has been mentioned. This is perhaps precisely the reason why these materials are so fascinating and beautiful. Thus the aim of this work is both a better physical understanding of the causes of these phenomena in properties of individuals grains and the achievement of realistic and beautiful animation sequences by the physical simulation of these grains.


In the time-decay model for data streams, elements of an underlying data set arrive sequentially with the recently arrived elements being more important. A common approach for handling large data sets is to maintain a \emph{coreset}, a succinct summary of the processed data that allows approximate recovery of a predetermined query. We provide a general framework that takes any offline-coreset and gives a time-decay coreset for polynomial time decay functions.
We also consider the exponential time decay model for $k$-median clustering, where we provide a constant factor approximation algorithm that utilizes the online facility location algorithm. Our algorithm stores $\mathcal{O}(k\log(h\Delta)+h)$ points where $h$ is the half-life of the decay function and $\Delta$ is the aspect ratio of the dataset. Our techniques extend to $k$-means clustering and $M$-estimators as well.


With the progress of society and the rapid development of the Internet and media industry,the legal protection of privacy has become increasingly important.The concept of privacy originated in the era of free economy in the United States and was spread rapidly worldwide.The article analyzes the development and contents of privacy as well as the current situation and problems in China,and further discusses the improvement of privacy rights.


Caborn-Welborn: Constructing a New Society after the Angel Chiefdom Collapse. DAVID POLLACK. University of Alabama Press, Tuscaloosa, 2004. 234 pp., illus., biblio., index. $29.95 (paper), ISBN 0-8173-5126-4.Reviewed by Jeremy R. DavisFrom the beginning of the fifteenth century through the first two centuries of European contact, waves of change rippled through Southeastern societies - populations thinned and shifted, mound building all but ceased, and the traditional bases of elite power strategies deteriorated. An expansive region surrounding the confluence of the Ohio and Mississippi Rivers has long been recognized as being especially hard hit by late prehistoric sociocultural upheavals, yet in the northern portion of this supposed "Vacant Quarter" a remnant population dubbed Caborn-Welborn coalesced out of the ashes of regional collapse to persist until the early eighteenth century. How these people reconstructed social, political, and economic relationships in such a setting is the focus of David Pollack's Caborn-Welborn: Constructing a New Society after the Angel Chiefdom Collapse.Chapters 1 and 2 introduce the topic and subject area. How populations respond to societal collapse is a topic of great anthropological interest. Unfortunately, migration to distant regions and /or dispersal to smaller sites in the wake of collapse often create a situation that is barely visible archaeologically. CabornWelborn peoples present a somewhat rare opportunity because they remained relatively nucleated and, according to Pollack, we know from whence they came. He wastes no ink in making the crucial point that Caborn-Welborn is the Angel chiefdom remade. To understand how this happened, he first investigates the character of Angel society and the factors that may have precipitated its atrophy.We are told that Angel was a relatively stable, nucleated, simple chiefdom that initiated sometime in the eleventh century and persisted into the fourteenth century, when environmental degradation and/or a disruption of interaction spheres undermined the basis of elite authority: agricultural tribute, prestige goods, and esoteric knowledge. Pollack does not rule out the possibility that other factors were involved in Angel's attrition. Whatever the cause, by circa A.D. 1400 Angel elites were out of power and the population at large had resettled forty miles down river near the mouth of the Wabash. Importantly, this scenario contradicts Hilgeman (Pottery-and Chronology at Angel, 2000), who claims that Caborn-Welborn originated outside of the Vacant Quarter or descended from an as-yet-unidentified local Mississippian group. Pollack rightly returns to this debate multiple times from various angles in subsequent chapters, citing continuity in subsistence practices, settlement pattern, and material culture as his evidence.Though Caborn-Welborn is expressed in various forms of material culture, ceramics are the most abundant and temporally and functionally sensitive. It is mostly upon ceramic data, therefore, that Pollack builds his case. Chapter 3 presents thorough descriptions and handsome illustrations of Caborn-Welborn ceramics. He assigns types only, forgoing the typevariety system in order to avoid an unwieldy and /or overly specific classification, and breaks down each into the kinds of vessels on which it is most commonly found. His descriptions and illustrations will undoubtedly serve as the definitive reference for future studies.In chapter 4, the author discusses sites known from previous work in the area in addition to those encountered in the course of recent surveys and systematic surface collections conducted by the author and colleagues; categorization of which are factored into a typology of sites based on size, layout, artifact density, and the supposed number of households that inhabited each. Most of the eighty sites are categorized as farmsteads, hamlets, small villages, or large villages. Pollack notes that this hierarchy sacrifices some reliability in exchange for efficiency, for example the degree to which reuse and settlement shifts factored into site size and layout is not currently understood. …


Stipends from a leadership grant are available from the University of Washington for students preparing for careers as researchers in the field of special education for children and youth with mild disabilities. Program emphasizes research methodologies and practical applications and collaboration with faculty mentors. Applications are welcome from members of groups traditionally underrepresented in the field of education at the doctoral level. Support includes tuition, $11,OOO/year, travel, and other benefits. For an application and more information, contact Dr. Joseph R. Jenkins, University of Washington, Experimental Education Unit, Box 357925, Seattle, WA 98195-7925; 206/543-4011. POSTDOCTORAL FELLOWSHIP IN DEVELOP-


IPv6 is enabled by default on most modern operating systems and as a result, networks today are at risk of transporting uncontrolled, unmanaged, and insecure IPv6 traffic. To help network engineers and administrators mitigate this risk, an in-depth understanding of IPv6 behavior is critical. This paper describes, in detail, the planning, design, implementation, and outcomes of a student project to build, operate, and maintain a research network for understanding IPv6 traffic behaviors. The project was structured to give networking students not only technical experience, but also the experience of working as a team on a complex project. The test environment was created using Cisco and Juniper router platforms and various operating systems including: MS Windows, Linux distributions, and MAC OS. The knowledge and skills gained by the students participating in this ongoing project will prepare them for meeting the challenges awaiting them as network administrators and engineers deploying IPv6 networks.


Discovery limits for the neutral SUSY Higgses in the l + jet + E miss t final state from A; H; h ! are calculated as a function of m A and tann. For the selection efficiencies and jet rejection factors results obtained from a detailed simulation of the CMS calorimeter are used. Possibility to suppress the irreducible Z; ! background with b-tagging in the associated production channels is studied. The expected reach in m A , tann parameter space for 3 10 4 pb ?1 taken at low luminosity is presented.


【Objective】To study the expression of PKC μ in Chinese hamster ovary cell(CHO cell).【Methods】The PKC μ primer pairs were derived from GeneBank sequence information based on similar species sequence.Using EMBL Data Library CLUSTALW tool,the highest homologues sequences were screened among the different species for PKC μ,and were used to design the primers.The primers were designed by using Generunner program.PKC μ was profiled by the RT-PCR technique.PKC μ was ligated to the pGEM-T plasmid vector.Transformants were taken from E.coli DH5α.Blue/white screening for recombinants in indicator plate.The plasmid construct was digested with restriction enzyme and was analyzed with gel electrophoresis.The product of restriction digestion with the sizes consistent and the predicated values was sent for DNA sequencing.Western blotting was used to analyze the PKC μ expressed in CHO cell.【Results】The presence of mRNA for the PKC μ expressed in CHO cell was determined by RT-PCR.PKC μ was found in CHO cell by Western blot analysis.【Conclusion】PKC μ was in CHO cell.That lays solid basis for further study the structure and function of PKC μ directly and the relationship with signal transduction pathways in cell.


Based on the analysis of the shortage in the traditional project management model,a model of project management——agile virtual enterprise(AVE) is presented.this article gives the building process of the project management of AVE,on which it analyzes the advantages of AVE and the influence on the three major elements of project management,and finally makes suggestions to the application of AVE to project management.


Rezension zu: Painting on Light. Drawings and Stained Glass in the Age of Durer and Holbein; Hrsg. Barbara Butts und Lee Hendrix; Los Angeles: J. Paul Getty Museum 2000; 330 S., 319 Abb., davon 198 in Farbe; ISBN 0-89236-578-1


This study aims to present a systematic data-driven bibliometric analysis of the water hyacinth (Eichhornia crassipes) infestation problem around the globe. As many solutions are being proposed in academia for its management, mitigation, and utilization, it requires investigation through a systematic scrutinizing lens. In this study, literature records from 1977 to June 2020 concerning research on water hyacinth are taken from Scopus for text analysis. Trends in the publication of different article types, dynamics of publication, clustering, correlation, and co-authoring patterns between different countries are observed. The cluster analysis indicated four clusters viz. (i) ecological works related to species, (ii) pollutant removal process and methods, (iii) utilization of biofuels for biogas production, and (iv) modelling works. It is clear from the networking analysis that most of the publications regarding water hyacinth are from India, followed by China and the United States. Sentiment analysis with the AFINN lexicon showed that the negative sentiment towards the aquatic weed has intensified over time. An exploratory analysis was performed using a bigram network plot, depicting and outlining different important domains of water hyacinth research. Water hyacinth research has passed the pioneering phase and is now at the end of a steady growth phase or at the beginning of an acceleration phase. In this article, an overview is given for the entirety of water hyacinth research, with an indication of future trends and possibilities.


This thesis contributed to the general understanding that relates to supramolecular polymer nanocomposite and to a process for the preparation of these polymer nanocomposites having some desired properties like self-healing ability.


. The vesicoureteral reflux (VUR) provokes development of nephrosclerosis in 48% of children with connective tissue dysplasia. Aim: Detection of clinical significance of biological markers of fibrogenesis (TGF-β1) and indices of collagen metabolism urine excretion in children with chronic pyelonephritis after conservative, endoscopic and operative correction of VUR for predicting the development of renal scarring was the aim of this trial. Material and Methods. 69 patients from 2 to 16 years with various variants of VUR (II-V grade) repair in a period of clinical-laboratory remission of pyelonephritis were examined. Results. We have found a significantly higher TGF-β1 (р<0,0001), free oxyproline (р<0,0000) and peptid-binded oxyproline (р<0,0000) urinary excretion in children with VUR regardless of the method of repair in comparison with children of control group. Conclusions. Thus, urinary excretion of TGF-β1 and oxyproline fractions can be used as markers for the development of renal parenchyma scarring in children with VUR.


To increase flexible property of epoxy resin and decrease curing temperature of silicone modified epoxy resin,the epoxy/polysiloxane hybrid materials are prepared by crosslinking hybrid of epoxy endgroup polysiloxane and epoxy resin via UV curing technology under a cationic photoinitiator.The structures and properties of epoxy/polysiloxane hybrid films are investigated by 13C NMR,29Si NMR,SEM,FTIR,and UV-vis analyzer,respectively.It is found that epoxy/polysiloxane films are obtained by in-situ crosslinking reaction under UV curing process without the phase separation.The epoxy/polysiloxane hybrid films have excellent transparence,thermal resistance,UV blocking and high adhesive properties,which can be applied to various optical fields such as the LED encapsulation materials and electronic encapsulation materials.


THE BEHAVIOUR OF ROAD CONSTRUCTION MATERIALS SUBJECTED TO REPETITIVE LOADING IS STUDIED IN RELATION TO PAVEMENT DESIGN . DETAILS ARE GIVEN OF THE EQUIPMENT WITH WHICH CYLINDRICAL SAMPLES OF PAVEMENT MATERIAL ARE SUBJECTED TO STRESS CONDITIONS SIMILAR TO THOSE EXISTING WITHIN A PAVEMENT SUBMITTED TO TRAFFIC LOADS. THE EQUIPMENT CONSISTS OF A NUMBER OF SENSORS WHICH MEASURE THE DYNAMIC STIFFNESS MODULUS, PERMANENT DEFORMATION, AND VARIATIONS IN THE VOLUME OF THE SAMPLES. BITUMINOUS MIXTURE SAMPLES ARE CITED AS EXAMPLES.


In this paper, we established new inequalities of Hermite-Hadamard-Fejer type for Riemann-Liouville and conformable fractional integrals.In this paper, we established new inequalities of Hermite-Hadamard-Fejer type for Riemann-Liouville and conformable fractional integrals.


We investigate the relationship between ideal membership of an operator and its pieces relative to several canonical types of partitions of the entries of its matrix representation with respect to a given orthonormal basis. Our main theorems establish that if $T$ lies in an ideal $\mathcal{I}$, then $\sum P_n T P_n$ (or more generally $\sum Q_n T P_n$) lies in the arithmetic mean closure of $\mathcal{I}$ whenever $\{P_n\}$ (and also $\{Q_n\}$) is a sequence of mutually orthogonal projections; and in any basis for which $T$ is a block band matrix, in particular, when in Patnaik--Petrovic--Weiss universal block tridiagonal form, then all the sub/super/main-block diagonals of $T$ are in $\mathcal{I}$. And in particular, the principal ideal generated by this $T$ is the finite sum of the principal ideals generated by each sub/super/main-block diagonals.


The penalties that Theseus imposes on his son in the third episode of Hippolytus comprise an uncharacteristic rough spot in an otherwise polished play. Theseus arrives back in Trozen to find his wife a suicide, an accusatory tablet dangling from her wrist. No sooner has he absorbed the tablet's message than he calls on his father Poseidon, reminding the god of the three wishes he once promised him and asking Poseidon to destroy Hippolytus on that very day, tif indeed you granted me reliable curses. If in the first Hippolytus Theseus cursed the innocent Hippolytus by appealing to his paternal Erinyes, his words might have disconcerted the spectators as much as or even more than the characterization of Phaedra as a porne (cf. Ar. Ran. 1043), and their shocked reaction might have played a role in Euripides' decision to revise the play. Keywords: Euripides' Hippolytus ; Phaedra; Theseus


Purpose
The purpose of this paper is to evaluate the agility performance level of manufacturing supply chains using Taguchi loss functions (TLFs) and design of experiment (DoE).

Design/methodology/approach
The proposed methodology is used for capturing the various agility losses using appropriate TLFs and the aggregated agility loss is calculated at different situations using DoE. The aggregated agility loss is analysed for comparing manufacturing supply chain agility performance.

Findings
The proposed methodology was applied to three Indian auto component supply chains, i.e. X, Y and Z. In total, 27 experiments were carried out using DoE and obtained results show that agility performance level is the highest for X followed by Z, whereas agility performance level is the least for Y.

Research limitations/implications
The proposed methodology is generic in nature and can be applied to a specific environment for comparing performance of different supply chains. The user has to identify the relevant agility enablers and capture the appropriate TLFs for the specific environment in which agility performance level has to be calculated and compared.

Practical implications
The proposed methodology provides an effective approach for evaluating agility performance. It can be used by the supply chain manger to assess the supply chain agility performance level of own company with its competitors. These comparisons will help the manufacturing company to find the areas where it should focus.

Originality/value
Many studies and researches related to implementation and evaluation of agile manufacturing are reported in the literature but very few studies are available for evaluating the supply chain agility performance. This study will definitely provide a guideline for measuring and comparing manufacturing supply chain agility performance in general and Indian automotive supply chain in specific.


Rape and sexual violence against Jewish women is a relatively unexplored area of investigation. This article adds to the scant literature on this topic. It asks: how and why did women's reproductive bodies (gender), combined with their status as Jews (race), make them particularly vulnerable during the Holocaust? The law against Rassenschande (racial defilement) prohibited sexual relations between Aryans and non-Aryans. Yet, Jewish women were raped by German men. Providing a more nuanced account than is provided by the dehumanization thesis, this article argues that women were targeted precisely because of their Jewishness and their reproductive capabilities. In addition, this piece proposes that the genocidal attack on women's bodies in the form of rape (subsequently leading to the murder of impregnated women) and sexualized violence (forced abortions and forced sterilizations) must be interpreted as an attack on an essentialized group: woman-as-Jew.


Effective management strategies of railroad environment should be prepared by the systematic management with the environment core technologies from the initial stage of the railroad environment to provide energy-efficient, safe, sound, and environment-friendly railroad service. In addition, the need for the development of railroad environment policy, like the improvement strategies and development strategies of railroad environment, is strongly required to actively prepare for the strengthening of environment regulations and supervision on the railroad environment problems. In this research, we studied the correlations between railroad environment policies and management strategies, and defined the component of environment policies. Moreover, we tried to present the direction of environment policies and mid-/long-term development plans that suit for the characteristics of Korean railroad through investigating the environmental policies of advanced countries.


The publication will give an overview on the preparation and execution of applied special foundation methods and a detailed description regarding installed soft-gel-plugs at the Greater Cairo Metro Line 3. Detailed description will explain general assumptions during tendering and design of grout-plugs, preparation of equipment, grouting procedure during execution and quality assurance activities (checking of drilling inclination, reporting of grouting) as well as reached final results. 1 GENERAL INTRODUCTION Cairo, biggest city of the Islamic hemisphere, has approx. 25 Million inhabitants. Due to increase of local traffic, narrow streets, construction sites or broken cars, daily traffic jams (Fig.1) and chaos on streets can be seen as usual. The first tramway opened in 1896 and tram is still an important part of public transportation. Additionally, there are approximately 2600 busses and countless mini busses, transporting approximately 1.3 Billion customers per year. Anyhow, they are also depending on free and accessible roads. The most important public transport system therefore is the Metro (Fig. 2), existing since 1987. Two lines with a total length of 61.5 km are already in operation and transporting approximately 950 Million customers a year (2004). Metro Line 3, connecting the airport to the city of Cairo, is already under construction and planned in several parts. The "National Authorization for Tunneling"(NAT), a Department of Ministry of Transport is the client for all construction activities. 2 CONSTRUCTION ACTIVITIES 2.1 Design and methods BAUER Egypt, contracted as a subcontractor of Metro Line 3 JV, executed the installation of open excavation pits for the start shaft of TBM and 4 stations with several ventilation shafts. Excavation and foundation levels for stations (Fig. 3) had been planned up to 26 m below ground water level and required cut-off-retaining-walls and soft-gelgrouting-plugs down to 60 m depth. Retaining walls, as well as separating trenches in the construction area had been installed as reinforced concrete cutoff-walls (cow) using several BAUER-cutters. Soil conditions at given sites had been investigated being cultural refill material (stones, concrete) and sand with silt or clay layers. After enclosing of a complete box, grouting activities started by installation of multi-stage valves at the design depth of soft gel plug. Installation had been done by two phase method: drilling with 133 mm drilling rods and grouting with soft gel. Soft gel prepared as a mixture of sodium silicate and reactant had been prepared by a continuous mixer and grouted by using 13 pumps grouting container. Soft-gel-plugs had a thickness from 4.5 to 8.5 m. Stations are located under existing roads. Depending on traffic, the roads had to be closed completely or half-side and traffic temporary diverted. Stations had been executed as water tight construction with cut-off-walls and grouting plug. Afterwards, the JV started excavation and construction of interior parts using top down method with temporary stiffening (Fig. 4). The tunneling machine (TBM), installed as a slurry-shield machine by Herrenknecht, has a diameter of 9.8 m and is driving from one station to the next station and manual shifted within the stations (Fig. 5). Connections to the stations, as well as to maintenance and to air circulation shafts had been made with installing a sealing block by cut-off-wall, cut by the TBM.


The East Shetland Basin of the Northern North Sea is the perfect natural laboratory in which to study the effects of multiple phase rift transection and interaction since it has undergone at least two major (Permo-Triassic and Upper Jurassic) rifting events. The superimposition of, and interaction between, the two rift phases strongly relates to the strike and dip (polarity) of normal faults accompanied with the linkage and cross cutting of faults through geological time. The talk will demonstrate the spectrum of structural geometries that result and their impact upon prospectivity. The results allow the definition of four main structural domains, each of which is related to the interaction of the two rift rifting events


This paper, taken the railway 10kV automatic blocking electric line as the research object, discusses some structure factors which may affect the ranging accuracy of traveling wave method in the practical application of traveling wave fault location device, and establishes the simulation model to verify. These structure factors include the effect of transition resistance, terminal load combination form and the line branches' number before fault point.


Introduction: Infectious mononucleosis is a clinical syndrome, particularly in children, adolescents and young adults. Since the clinical and laboratory characteristics of infectious mononucleosis are different according to geographical regions and age groups, studies in different regions can be crucial in improving the diagnosis and treatment of patients with infectious mononucleosis. Objective: This study aimed to investigate the frequency of demographic, clinical and laboratory characteristics of patients with infectious mononucleosis admitted to 17th shahrivar Hospital of Rasht since 2009 to 2013. Materials and Methods: In this descreptive retrospective study, medical records of all patients with a diagnosis of infectious mononucleosis admitted to 17th Shahrivar Hospital of Rasht between 2009 and 2013 were examined. Patents' demographic, clinical and laboratory findings were collected and analyzed by descriptive statistics using SPSS software version 18. Results: In this study, 99 patients with infectious mononucleosis with an average age of 6.19 ± 3.03 were assessed of which 55% were boys. The most common season was summer (35%), followed by spring (30%). The most common chief complaints were fever (88.8%), and pharyngitis (63.3%). The mean duration of disease was 6.19 ± 3.41days. The most common clinical signs were tonsillopharyngitis (98.9%), cervical lymphadenopathy and fever (9/93%).. Leukocytosis was seen in 73.7% of patients and also, lymphocytosis in 62.6%, atypical lymphocytosis in 29.3%, anemia in 13.1% and thrombocytopenia in 6.1%. The high ESR, increased liver enzymes, positive monotest and positive IgM-VCA test were detected in 54.1 %, 46.5 %, 11.1 % and 9/92 % of subjects, respectively. The most common complication was respiratory distress in 5 patients. One patient died with respiratory distress and bleeding. Conclusions: The most common chief complaints were fever and sore throat; and cervical lymphadenopathy, fever and tonsillopharyngitis were most common signs. It is recommended that differences in the clinical manifestations and their prevalence in our region, be considered in the diagnosis. Conflict of interest: none declared


A study of 90 days duration was conducted on 18 multiparous crossbred cows (363±14kg, body weight; in II or III lactation; 3,000-4,500kg milk yield per lactation) randomly allotted to 3 dietary treatments with 6 animals in each group in a completely randomized design to investigate the effect of two slow release non protein nitrogen (SRNPN) products on feed intake, milk yield, milk composition, blood biochemical parameters and cost economics. The concentrate mixture for control group was formulated with maize, gram husk, ground nut cake, wheat bran, deoiled rice bran, salt and mineral mixture. The other two experimental concentrate mixtures were prepared by totally replacing ground nut cake with calcium salts of fatty acid coated urea (CFCU) and Hydroxypropyl methylcellulose coated urea (HMCCU) at 2.42%. The cows were offered fixed quantity of Napier green fodder (10kg/cow/day) and ad libitum paddy straw. The daily allowance of respective concentrate mixture offered to each cow was calculated based on body weight, previous week milk yield and roughage intake to meet the nutrient requirements of as per ICAR (2013). Incorporation of either of the coated urea products in concentrate mixtures did not affect the total DM intake, milk yield (13.94 to 14.11kg/d), milk composition (Milk fat, Protein, SNF and Lactose) and blood biochemical (Blood urea nitrogen, Glucose and total protein). Though non significant, the average daily cost of feeding (Rs/d) was lowered in CFCU (228.14) and HMCCU (215.98) diet fed cows compared to control group cows (237.08) by 3.77 and 8.89% respectively. Whereas, the cost of feeding (Rs) per kg milk production differed significantly (P<0.01) with highest in control diet fed group (16.80) while in CFCU (15.43) and HMCCU (15.49) fed group it was lower. CFCU and HMCCU can be included at 1% of dry matter or 2.42% in the concentrate replacing the conventional protein sources, without affecting the milk yield and its composition in cross bred cows and reducing the feed cost per kg milk production.


Abstract : A complete, connected Einstein space of dimension m greater than 2 on which there exists a vector field generating globally a one-parameter group of non-homothetic transformations is homeomorphic with the m-sphere. This statement is valid for any complete, connected Riemannian manifold if it were known for a manifold of (positive) constant scalar curvature. Evidence is presented strengthening this conjecture. It is shown that if M is a compact Riemannian manifold which is not a homology sphere, then an infinitesimal conformal transformation of M is an infinitesimal isometry. In particular, if a compact, simply connected symmetric space of a connected Lie group admits a non-homothetic transformation (belonging to the connected component of the group of conformal transformations of M) then M is isometric with the m-sphere. (Author)


Purinergic leucine-rich repeat containing (NLR) proteins have been shown to control viral infection. Here, we show that the NLR family member NLRP3 and the purinergic receptor P2Y2 constitutively interact and regulate susceptibility to HIV-1 infection. We found that NLRP3 acts as an inhibitory factor of viral entry that represses F-actin remodeling. The binding of the HIV-1 envelope to its host cell receptors (CD4, CXCR4, and/or CCR5) overcomes this restriction by stimulating P2Y2. Once activated, P2Y2 enhances its interaction with NLRP3 and stimulates the recruitment of the E3 ubiquitin ligase CBL to NLRP3, ultimately leading to NLRP3 degradation. NLRP3 degradation is permissive for PYK2 phosphorylation (PYK2Y402*) and subsequent F-actin polymerization, which is required for the entry of HIV-1 into host cells. Taken together, our results uncover a mechanism by which HIV-1 overcomes NLRP3 restriction that appears essential for the accomplish-ment of the early steps of HIV-1 entry. Samples from lymph nodes, ileum and fascicularis 5 old by intrarectal inoculation with a single dose of 50 50% animal infectious doses (AID 50 ) of SIV mac251 . during animal necropsy (for SIV mac251 -infected animals, on days 701 to 738 after SIV infection) after sedation of the animals (ketamine chlorhydrate 10 mg/kg) followed by euthanasia (injection of sodium pentobar-bital 180 mg/kg). Non-human primates (NHP, M. fascicularis HEK293T cells siGenome (Dharmacon) smart pool selected composed of a pool of four siRNAs the following sequences for CBL (siRNA1, 5 0 -GGAGACACAUUUCGGAUUA-3 0 ; siRNA2, 5 0 -GAUCUGACCUGCAAUGAUU-3 0 ; siRNA3, 5 0 -GACAAUCCCUCA CAAUAAA-3 0 ; siRNA4, 5 0 -CCAGAAAGCUUUGGUCAUU-3 0 ). The siRNAs used as control with siGenome smart pool are a pool of four on target plus non-targeting siRNAs (Dharmacon). siRNAs transfection of HeLa CD4 + CXCR4 + or HEK293T cells were performed with 20 nM siRNA using Oligofectamine (Invitrogen) according to the manufacturer's instructions. Western blot analyses and experiences of HIV-1 infections or cell fusions were performed 48 hours after siRNA transfection. For siRNA transfection of MDMs, the protocol was previously described (Allouch et al., 2013): MDMs were seeded (0.5x10 6 MDMs/0.5 ml/ well of 12-well plate in macrophages medium + 10% FBS) and let to be attached at 37 (cid:1) C for 2 hours prior siRNAs transfection. The siRNAs transfections were performed with the INTERFERin (Polyplus Transfection). Different amounts of siRNAs were pre-diluted in 1 mL of Opti-MEM in which 20 m L of INTERFERin were added and the transfection mix was let to incubate at room temperature for 10 minutes. The transfection mix (250 m l) was added to 0.5x10 6 MDMs at the final concentrations of 50 nM of siRNAs against CBL. Equal amounts of the on target plus non-targeting siRNAs were added to the control MDMs. The MDMs were then incubated at 37 (cid:1) C for overnight. The medium was replaced with fresh macrophage medium supplemented with 10% FBS prior to the infections. At 72 hours post-CBL siRNA transfection MDMs were infected with HIV-1 cell assayed blot. For short hairpin RNA (shRNA) lentiviral particles transduction, pLKO.1 shRNA expression lentiviral vector for each targeted was purchased from Thermo Scientific. The shRNAs used in knockdown experiments the following sequences for P2Y2 (shRNA1, 5 0 -ATGTTCCACCTGGCTGTGTCTGATGCACT-3 for NLRP3 (shRNA1, 5 0 -TTCTTGAAGTGTTTCTAACGC-3 , shRNA2, 5 0 -AAACAGTAGAACAATTCCAGC-3 and pLKO.1 empty vector control. Lentiviral vector cotransfection of three plasmids coding for the gag-pol HIV-1 genes (pCMV- HIV-1-GAG-POL), for the vector genome shRNA (pLKO.1 and for the plasmid coding for an envelope of VSVG (pMDG-VSV-G). Co-transfection was performed in HEK293T cells using Fugene transfection reagent (Promega) according to the Two days transfection, were m m cellulose acetate frozen For transduction, lentivirus monocytic THP1 cell into CXR4 cells THP1 Cell slides were then incubated during overnight for immunofluorescence with anti-P2Y2 (Alomone), anti-NLRP3 (Adipogen), anti-CD163 (BD laboratories) or anti-gp120 (2G12) (AIDS Research and Reference Reagent Program, Division of AIDS, NIAID) or for immunochemistry with anti-NLRP3 (Sigma) after perme-abilization in 0.3% Triton for 5 minutes and saturation in PBS-FBS 20% for 1 hour. Then, cells were incubated with appropriate sec-ondary antibodies conjugated to Alexa Fluor 488, 546 or 647 fluorochromes (Life technologies) at room temperature during 1 hour and 30 minutes. Actin was stained with Alexa Fluor 594 Phalloidin for 30 minutes at room temperature. DNA was stained with Hoechst 33342, Trihydrochloride, Trihydrate (Life technologies) and then cells were mounted with Flouromount G medium (Southern biotech). Proximity Ligation Assay (DUOLINK (cid:2) , Sigma) was performed according to the manufacturer's instructions using anti-NLRP3 (Adip-ogen) and anti P2Y2 (Alomone) as primary antibodies. Images of cells were acquired by laser-scanning fluorescent confocal microscopy Leica SPE with LAS-X software (Leica) with 8 bits configuration and using a 63X oil objective (1.4 numerical aperture). Leica Microsystem immersion oil (11513859) used and imaging was performed at temperature. Confocal images


Job Satisfaction is commonly acknowledged to be a critical issue for employees. This study attempts to fill part of this void in literature by examining the factors affecting job satisfaction among 100 employees of a Public Ltd, Nagpur. The study's findings suggest that higher job satisfaction indicates higher performance. The main objective was to see if there was any relationship between job performance and job satisfaction. The research was assessed by using various instruments.
Key words: Job satisfaction, job performance, factors of job satisfaction


The thermodynamic functions of hydrogen-bond complex formation for a number of phenols with tetrahydrofuran in carbon tetrachloride have been determined by a calorimetric method. The phenols studied included phenol, pentafluorophenol, pentachlorophenol, pentabromophenol and 2,6-dimethylphenol. The heats of solution in CCl4 were determined in the range of low concentrations only for the substituted phenols. The equilibrium constants and enthalpies of complex formation are compared with the corresponding data obtained by infrared spectroscopy. The effect of acidity, steric hindrance and ability to form intramolecular hydrogen bonds is discussed in terms of the ability of phenols to form intermolecular hydrogen-bond complexes.


Without the use of retarders, different applications in modern concrete technology would not be possible. The effect of retarders is among other factors influenced by its adsorption on first formed hydration products. Due to this, it is possible to enhance the retarder's impact on cement hydration significantly by controlled addition. This study presents investigations on cement pastes with additions of different retarders in varying dosages and addition times. Effects on the hydration process, setting behaviour and microstructural phase formation were monitored. With delayed addition after 5 min, the retarding effect was enhanced independent of the cement and the retarder type. However, with delayed addition after 15 min, an additional increase of the retardation depends on the cement admixture combination. Comparing calorimetry, setting time and ultrasonic measurements, similar observations were obtained. The correlation between the initial set and the derivation of the ultrasonic pulse velocity yielded...


In order to form a psychotherapy system in patients with psychoendocrine syndrome that developed on the background of thyroid gland and adrenal cortex metabolic disorders, a prospective study of 300 patients undergoing therapy in Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of the Ministry of Health of Ukraine was conducted. A type-specific contranozogenic and contrasemiotical psychotherapy and psychorehabilitation system orientated on patients with impaired thyroid hormone and adrenal cortex metabolism, is implemented in two vectors: decreasing the effect of nosogenic psychotraumatisation factors and correcting psychopathological semiotics. The developed system demonstrates a high level of efficiency on pathopsychological and psychopathological components of the psychoendocrinal syndrome in endocrine dysfunctions compensation state in all groups of patients


Over the past thirty years, the disappearance, if not the death, of the intellectual in France has been the focus of significant conversation and debate. Yet a good bit earlier, two writers who epitomized that very figure of the intellectual, Jean-Paul Sartre and Albert Camus, in works written after their bitter break, seemed to have already sensed this decline. The present essay explores what Camus's novel La Chute [The fall] and Sartre's autobiography Les Mots [The words] share thematically and, in particular, how both works anticipate the fall of the French intellectual.


Recommended citation: Williams-Jones, A.E. and Vasyukova, O., 2015. Fluoride-silicate melt immiscibility and the formation of the pegmatite-hosted Strange Lake REE deposit, Quebec-Labrador. In: Simandl, G.J. and Neetz, M., (Eds.), Symposium on Strategic and Critical Materials Proceedings, November 13-14, 2015, Victoria, British Columbia, British Columbia Ministry of Energy and Mines, British Columbia Geological Survey Paper 2015-3, pp. 91-96.


Fused quartz powder (d50=19μm) was used as raw material, and nano-Nd2O3 was used as additive with dosages of 1% (in mass, similarly hereinafter), 2% and 3%. The effects of nano-Nd2O3 on crystallization and sintering behavior of the materials at various temperatures (1300 °C/1h, 1350 °C /1h and 1400°C /1h) were studied by measurements of apparent porosity, bending strength and thermal expansion ratios (RT~1200°C), and analyses of XRD and SEM. The results of XRD and thermal expansion ratios analysis showed that 3% nano-Nd2O3 additive had excellent effect on inhibiting crystallization of the samples sintered at 1350 °C and 1400°C. The results showed that the samples sintered at various temperatures with 3% nano-Nd2O3 had the lowest apparent porosity and more compact microstructure. This indicated that 3% nano-Nd2O3 had better effect on facilitating sintering of fused quartz materials.


15 In viruses, post-translational modifications (PTMs) are essential for their life cycle. Recognizing 16 viral PTMs is very important for better understanding the mechanism of viral infections and finding 17 potential drug targets. However, few studies have investigated the roles of viral PTMs in virus-human 18 interactions using comprehensive viral PTM datasets. To fill this gap, firstly, we developed a viral 19 post-translational modification database (VPTMdb) for collecting systematic information of viral PTM 20 data. The VPTMdb contains 912 PTM sites that integrate 414 experimental-confirmed PTM sites with 21 98 proteins in 45 human viruses manually extracted from 162 publications and 498 PTMs extracted 22 from UniProtKB/Swiss-Prot. Secondly, we investigated the viral PTM sequence motifs, the function of 23 target human proteins, and characteristics of PTM protein domains. The results showed that (i) viral 24 PTMs have the consensus motifs with human proteins in phosphorylation, SUMOylation and 25 N-glycosylation. (ii) The function of human proteins that targeted by viral PTM proteins are related to 26 protein targeting, translation, and localization. (iii) Viral PTMs are more likely to be enriched in 27 protein domains. The findings should make an important contribution to the field of virus-human 28 interaction. Moreover, we created a novel sequence-based classifier named VPTMpre to help users 29 predict viral protein phosphorylation sites. Finally, an online web server was implemented for users to 30 download viral protein PTM data and predict phosphorylation sites of interest. 31


This study aims to analyse the factors that influence the interest of muzakki in paying zakat profession through zakat institution. The constructs used in this study are religiosity and reputation as the variables used in measuring the interest. This research was conducted in Ponorogo district. The research method used in this research is quantitative. The researcher approaches this study with survey method, in which the scale of instrument measurement used is the Likert scale as well as using purposive technique in sampling. The data analysis technique used in this research is regression analysis and the data is processed by using SPSS for windows version 20. The results of this study indicate that the factor of religiosity and reputation have a statistically significant effect on the interest of muzakki in paying zakat profession through zakat institution in Ponorogo district.


Summary

The nucleotide and amino acid sequences of the movement protein (NSm) genes of five isolates of Groundnut bud necrosis virus (GBNV) originating from different hosts and parts of India such as cowpea and tomato from Kerala, groundnut from Tamil Nadu, and potato from Madhya Pradesh and Rajasthan were determined and compared to the known NSm sequences. Sequence analysis revealed that the NSm genes of GBNV isolates were identical in length (924 bp encoding 307 amino acids). GBNV isolates shared maximum identity (98–100%) at amino acid levels with GBNV-Type isolate, while 82–83% and 34–65% amino acid sequence identities were observed with Watermelon silver mottle virus and other Tospoviruses respectively. The NSm genes among GBNV isolates originating from different hosts and locations appeared highly conserved (93–100%), suggesting their common origin.


This paper provides a first assessment of the Federal Reserve's recent Maturity Extension Program, dubbed Operation Twist 2. Despite the mere exchange of short-term for long-term Treasury securities, the announcement effect is comparable to the second Large Scale Asset Purchase programme (LSAP2). The portfolio rebalancing channel, however, is countervailed by the issuance of even more Treasury coupon securities, which may explain the temporary nature of the observed interest rate effects. In the extreme, Operation Twist 2 and LSAP2 can be viewed as just offsetting the adverse impact of the pronounced increase in outstanding government securities.Full publication: Threat of fiscal dominance?


Abiu is on introduced plants from the Amazon that has the potential to be developed in Indonesia. Abiu has good taste and is also rich benefits for health. Fruit defects are the main problem that decreases the quality appearance of abiu fruits. This research aimed to determine the effect of pesticide active compounds used with different application periods on the appearance of abiu fruits. Research was conducted at Kampung Babakan Lebak, Kelurahan Balumbang Jaya, Kecamatan Bogor Barat, and the Post-Harvest Laboratory of the Department of Agronomy and Horticulture, IPB University Bogor. The experimental design used a split-plot, randomized complete block design with five replications. The main plot was the application periods, namely 1,2,3 Week after anthesis (MSA) (V1); 1,3,6 MSA (V2); and 1,4,7 MSA (V3). The sub-plot was the pesticide active compounds, namely mancozeb 80 WP and streptomycinsulfate 20 WP (P1); propinep 70 WP (P2); profenofos 500 EC (P3), and control (P4). The results indicated that the pesticide active compounds had a significant effect on fruit smoothness. The application of pesticides at different periods and their interactions with the pesticide active compounds did not have a significant effects on the smoothness of the abiu fruit. The best treatment was the mankozeb and streptomycinsulfate pesticides which could maintain the smoothness of the abius fruit by 77.31%.


Tourism traffic must be quantified through four observing units' categories: custom houses; quartering units; internal and external travel agencies on home teritory; familiy budgets. These observing units allow to quantify the statistical observation's object and its cyclicity.


[4749-37-5] C4H5NO4 (MW 131.10)

InChI = 1S/C4H5NO4/c1-9-4(6)2-3-5(7)8/h2-3H,1H3/b3-2+

InChIKey = OVZCRDHFYPVIRT-NSCUHMNNSA-N

(E)

[52745-92-3]

InChI = 1S/C4H5NO4/c1-9-4(6)2-3-5(7)8/h2-3H,1H3

InChIKey = OVZCRDHFYPVIRT-UHFFFAOYSA-N

(E)-ethyl ester

[5941-50-4] C5H7NO4 (MW 145.13)

InChI = 1S/C5H7NO4/c1-2-10-5(7)3-4-6(8)9/h3-4H,2H2,1H3/b4-3+

InChIKey = HOTCCRPFEOUSLL-ONEGZZNKSA-N

(Diels–Alder dienophile;4 Michael acceptor13)

Physical Data: bp 73 °C/10 mmHg; mp 38 °C.1

Preparative Methods: by reaction of Methyl Acrylate with either nitryl chloride1 or N2O4/iodine (see Nitrogen Dioxide and Iodine),2 followed by elimination with sodium acetate (eq 1). An Organic Synthesis preparation of the corresponding ethyl ester using N2O4/iodine has been reported.3

(1)

Purification: can be crystallized from methanol–water or vacuum distilled.1 However, significant losses were reported on vacuum distillation of the ethyl ester, which was best crystallized from pentane at −15 to 0 °C.3

Handling, Storage, and Precautions: lachrymatory solid; best stored in a refrigerator.


The invention relates to an application of nano-zinc in metalized solar cell slurry. The application is characterized in that nano-zinc is added in the metalized solar cell slurry, wherein the diameter of nano-zinc is smaller than or equal to 50nm, and the content of nano-zinc used in metalized solar cell conductive front slurry ranges form 0.02 wt% to 0.1 wt%. The application of nano-zinc in metalized solar cell slurry improves the weldability and the welding tension of crystalline silicon solar cell metalized main grids on the premise of not sacrificing the conductivity or the conversion efficiency of solar cells.


The aim of this paper is present a study on the development of a fuzzy logic application to evaluate the susceptibility of the Total Productive Maintenance (TPM) methodology in industries which provides a diagnosis of the set of indicators from the inference system. This study is relevant because the TPM in the industries has been shown as a management tool with excellent results, contributing to increase the general capacity of utilization of the plants with direct impact on the availability of equipment and consequently increase of production. This work developed an application that through fuzzy logic, can evaluate the susceptibility of TPM deployment and identify the areas that offer opportunity for improvement and potential for this philosophy. To do so, the definition of system input variables and the criteria for implementation form the basis of this study.


Abstract In this paper, I argue that agent-based modeling and simulation in a complexity framework can be useful scientific tools to think about the uncertain future. I will argue that the usefulness of this approach depends on its capability to generate surprise and discuss what conditions are needed for surprises to happen. The main value of agent-based models and simulations is to produce possible futures. This is the anticipation function of a model. It is important to emphasize that anticipating possible futures is different from predicting the most likely future evolution of some variables and requires a different understanding of what the science of economics can achieve. Therefore, I will discuss some epistemological thoughts related to the economic study of uncertain futures. Building on these foundations, the paper presents three methodological approaches of how agent-based models and simulations could be used to anticipate potential futures.


The 515 kHz ultrasound-initiated reduction of AuCl4- to Au(0) was examined as a function of the concentration of various surface-active solutes. The amount of AuCl4- reduced in the presence of ethanol, propan-1-ol, and butan-1-ol was found to be dependent on the surface excess of the alcohol at the gas/solution interface, i.e., the relative concentration of the alcohol at the gas/solution interface compared to the bulk solution concentration. The efficiency of reduction of AuCl4- in the presence of the surfactants sodium dodecyl sulfate or octaethylene glycol monodecyl ether was found to be related to the monomer concentration of the surfactant in solution. The light emitted (sonoluminescence) during ultrasonic irradiation of the aqueous solutions was also monitored and compared with the trends observed in the sonochemical experiments. The sonoluminescence was observed to be significantly reduced in the presence of alcohol, and the effect was correlated with the surface excess of the alcohols at the gas/s...


Introduction. The role of the lipid content of atherosclerotic plaques in outcomes of stenting is in need of further investigation. This study is aimed at assessing the outcomes in patients with lipid-rich and non-lipid-rich plaques following the drug-eluting stent (DES) implantation using the method of optical coherence tomography (OCT). Materials and methods . The total of 43 examined patients included 26 patients in the lipid-rich plaque group and 17 in the non-lipid-rich plaque group. The characteristics of plaques were examined by OCT. The percentages of sites presenting malapposition, tissue protrusion, dissection and thrombus were calculated according to established criteria. Results and discussion . The percentage of patients with the type 2 diabetes, the percentage of malapposition and tissue protrusion were all higher in the lipid-rich plaque group. Residual thrombus was more frequent in the lipid-rich plaque group in comparison with the non-lipid -rich plaque group. Conclusions. Lipid-rich plaques correlate with a higher incidence of malapposition, tissue protrusion, and thrombus following the stenting procedure, thus confirming the link between the atherosclerotic lesion type and suboptimal stenting outcomes.


To compare unenhanced 3D water‐excitation sensitivity‐encoding time‐of‐flight (WEST) and gadolinium‐enhanced 3D sensitivity‐encoding water‐excitation multishot echo‐planar (SWEEP) MR angiography (MRA) with regard to conspicuity of uterine arteries in correlation with digital subtraction angiography (DSA).


It is known that the internet altered the business model of the travel industry. Due to the exponential growth of its' users, several companies established online booking services. For instance, Traveloka.com and Tiket.com in airline ticket booking and the Rajakamar.com in hotel reservation. Online Travel Agencies (OTA) have been gaining important attention in recent years. Yet, limited literature focuses on discussing the development of such services in Indonesia. The research's purpose was to analyze the development of OTAs in Indonesia, particularly in its services, employment, and users. The study involves 52 Indonesian OTAs. A structured interview and website-based observation had been done. The results show that only a few OTAs offer direct payment system, while most agencies located in the capital city, Jakarta. Moreover, most of OTAs is on the Business-to-Consumer state. Meanwhile, most of the founders were an entrepreneur with information and technology background. Furthermore, the most popular service offered was the tour and travel ticket sale. There are several suggestions outlined for future research and practical implications for OTAs. Keywords—intermediaries; online travel agencies; tourism industry


In this paper, a wireless tracking control problem with varying time delay longer than one sampling interval is discussed, and a preview controller is employed for precise motion control. A delay-dependent system model is first introduced and a reference generator is then employed to model the previewed future reference. The system model is augmented with the reference generator and an optimal controller is synthesized to minimize a quadratic cost function of tracking errors and control inputs. A time-varying Kalman filter is designed for state estimation and feedback control. To make the Kalman filter feasible under long time delay, a linear regression model is proposed for delay estimation based on past measurements. A new wireless protocol called RT-WiFi is developed for high-speed and real-time control applications. Using the delay measurement from the RT-WiFi network, simulation studies is conducted to verify the effectiveness of the proposed algorithm.


The reliability of an AC source in the telecommunication field has greatly increased thanks to the redundancy principle implemented in digitally controlled inverters running in a parallel system. To improve the safety of such a system, supervision architecture has to be elaborated around the inverter system. An inverter supervisor (IS) is presented. It can be integrated in a system in 2 different ways: either as a local main supervision unit for a simple system or as an interface mechanism in a more complex installation. The two approaches are discussed.


Yogyakarta has a problem related to pedestrians. The inappropriate implementation of crossing facility and disobedience of pedestrians while crossing the street leads to conflicts between pedestrians and vehicular traffic. Taking the road section of Colombo Street as the case study, this research proposed pelican crossing with independent and coordination time signal operation. Using Aimsun software, the existing traffic signal, geometric design, traffic flow and turning proportion were taken into account to build the initial model. Afterwards, a calibration of queue length and a validation of vehicle speed were carried out to obtain a basic model which represents the existing condition of the system. Comparing the basic model and the alternatives in terms of performances of junctions, road section and pedestrians in the pelican, this research resulted in setting double cycling of pelican as 100 seconds for the independent operation and setting common cycle time 120 seconds for the coordination operation as the best alternatives. In addition, the implementation of pelican crossing brought about the reduction of vehicle speed in the road section so that the safety of pedestrian increased. Keywords : Pedestrian, pelican crossing, Aimsun, signal time, speed


All three types of thyroid hormone deiodinases are selenoenzymes containing the rare amino acid selenocysteine in their active centers. Dietary selenium (Se) deficiency leads to a reduction of deiodinase activity demonstrating that Se impacts directly on the thyroid hormone axis. The current understanding of thyroid hormone metabolism holds that hepatic deiodinases significantly contribute to the activation of systemic thyroxine. However, all types of deiodinases are expressed in a highly regulated and tissue specific manner suggesting local control mechanisms of biologically active T3 levels. Mice haven been generated in which the selenocysteine-specific tRNA gene (trsp) can conditionally be inactivated. We have crossed these mice with a transgenic mouse strain in which hepatocellular expression of Cre recombinase is under control of the albumin promoter (Alb-Cre). These liver-specific trsp knockout mice (Alb-Cre; trspf/f) are unable to synthesise hepatic selenoproteins. Nevertheless, they are born normally and survive into adulthood. Plasma Se reduced by >80% in Alb-Cre; trspf/f mice. This indicated that plasma selenoprotein P (SePP), the major plasma Se carrier protein, is mainly secreted by the liver and that inactivation of trsp is achieved in a significant proportion of hepatocytes. In the liver, type I deiodinase activity is strongly reduced in spite of normal transcript levels. We are now testing if plasma thyroid hormone levels in these mice are affected and whether enhanced deiodinase expression in other organs compensates for the loss of hepatic deiodinase. This is the first animal model in which all hepatic deiodinases are inactivated at the same time.


Along with the constant developing of our socialistic market economy and the deepening of the reform of institutions,the existing accounting system for public institutions can't meet the development needs of social situations.The reform of accounting system is urgent.This article takes the present Institution accounting system's defect as a breakthrough point,and analyzes the main problems which exist in the accounting system,and put forward a few suggestions about the reform of accounting system in public institutions.


Disclosed are: a polymerizable composition which can provide a resin molded article suitable as an electric material for use in an electric circuit board or the like, is suppressed in the increase in viscosity over time and has a high polymerization conversion rate; a process for production of the polymerizable composition; a resin molded article produced by using the polymerizable composition; a process for producing the resin molded article; a cross-linked resin molded article having excellent electrical insulation properties, adhesiveness, mechanical strength, heat resistance, dielectric properties and others; and a process for producing the cross-linked resin molded article.


Antibody titers to Epstein‐Barr virus (EBV)‐related antigens, i.e. viral capsid antigen (VCA), the D and R components of the early antigen (EA) complex and the EBV‐associated nuclear antigen (EBNA), were determined in a series of 86 patients with non‐Hodgkin lymphomas and in 150 matched control subjects. The lymphoma patients belonged to four histological groups: diffuse, nodular, hyperbasophilic malignant lymphoma (HML) and unclassified. The EBV‐related serological data were compared to the incidence of antibodies to other herpes viruses, i.e. cytomegalovirus (CMV), herpes simplex virus (HSV) and varicella zoster virus (VZV), and correlated with immune disorders, which are particularly frequent in the HML type of lymphoma. The results revealed a significantly higher incidence of anti‐EA‐D titers in lymphoma patients and slight but significant increases in the geometric mean anti‐VCA titers in the HML and unclassified group of patients. These elevated anti‐EBV titers in patients were not associated with an increase in titres of antibodies to other herpes viruses. They did not correlate with the signs of immune deficiency observed or with the incidence of auto‐antibodies.


To utilize the logic of dialectical thinking in the clinical diagnosis and relevant treatment and to cite numerous Obstetrics and Gynecology clinical facts,in order to show the general character between philosophy and medical science.To reduce and solve medical disputes,wide philosophical mode of thinking is applied to make the clinical diagnosis and treatment of Obstetrics and Gynecology more flexible and perfect, clinical diagnoses more accurate,treatment plans more rational。


* Representing the Mussalman: Then and Now, Now and Then, Shahid Amin, University of Delhi* Refiguring the Fanatic: Malabar 1836-1922, M. T. Ansari, University of Hyderabad* A Practice of Prejudice: Gandhi's Politics of Friendship, Faisal Fatehali Devji, Yale University* The Anomaly of Kabir: Caste and Canonicity in Indian Modernity, Milind Wakankar, State University of New York* Death of a Kotwal: Injury and the Politics of Recognition, Anupama Rao, Columbia University* Framing Custom, Directing Practices: Authority, Property and Matriliny under Colonial Law in Nineteenth-century Malabar, Praveena Kodoth, Centre for Development Studies, Trivandrum* A Poetics of Resistance: Investigating the Rhetoric of the Bardic Historians of Rajasthan, Rashmi Dube Bhatnagar, independent scholar, Renu Dube, Boise State University and Reena Dube, Indiana University* The Work of Imagination: Temporality and Nationhood in Colonial Bengal, Prathama Banerjee, Lady Sri Ram College, Delhi


Aiming at the defects of needing long time and using series shifting capture method, the paper deals with series/parallel hybrid structure to finish rapid capture of DS/FH hybrid spread spectrum systems, and analyzes the system statistical performance. The simulation results demonstrates that capture probability of hybrid parallel is smaller than that of serial capture when the signal noise ratio is same.


The present work aims at analysing the potential of pomegranate juice which is used for the treatment of dengue fever as it is used in increasing the bodys immune power by increasing the platelets count. The phytochemical characteristics of pomegranate juice extract is studied and compared with papaya leaf juice extract. Both the papaya leaves and pomegranate are naturally and easily available, which are non toxic, has no side effects. In our study, the effectiveness of pomegranate juice was studied by introducing the juice into cyclophosphamide induced swiss albino mice. Before the administration, the platelet count, White Blood Cells (WBC) and Red Blood Cells (RBC) was analysed, after the induction of cyclophosphamide platelet count and white blood cells decreased from 9,74,200, 11380 to 8,42,400, 6140 and no significance for RBC. The blood samples were rechecked after introduction of pomegranate juice extract. It was observed that platelet count, WBC increased significantly, but there was no significant increase in RBC. Therefore, it can be concluded that pomegranate juice significantly increases the platelet count and WBC.


The problem of master-slave fault tolerant synchronization for a class of chaotic systems with multiple time-delays is considered. A fault tolerant synchronization is designed for a fault occuring in chaotic systems. Whether the fault happens in the chaotic systems or not,the synchronization method not only guarantees that the error system is globally asymptotically stable,but also satisfies a prescribed performance level. The fault tolerant controller contains two parts:the state feedback controller and fault compensator. A delay-dependent condition based on linear matrix inequality (LMI) is proposed for fault tolerant controller. The effectiveness of proposed design method is demonstrated by a simulation example.


ABSTRACT Endophytic microbes are an intriguing group of organisms colonise the living, internal tissues of their host usually higher plants. Endophytes does not cause any infection or symptom in the host cells and produce natural bioactive compounds considered as an alternative source of plant secondary metabolites. The present review focused on the biodiversity of both bacterial and fungal endophytes and their isolation, culturing, staining methods, immunological detection, biochemical, molecular identification proceduresAssociate Professor and bioactive compounds of pharmaceutical as well as clinical importance. Keywords: Endophytes, Bioactive compounds, Isolation, Molecular identification. INTRODUCTION An endophyte is a bacterium or fungal microorganism, that spends the whole or part of its life cycle colonizing healthy tissues of host plants without causing any apparent symptom of disease [1] . The Endophytic microorganisms like their host plants, represent a huge diversity of microbial adaptations, developed in special and sequestered environments


Software developers often use identifiers to link program elements with domain knowledge. If identifiers in a program have inappropriate name, developers consume much time to comprehend the program. This paper proposes a method to extract and gather verb-object (V-O) relations from source code written in object-oriented programming language. For each several domains, dictionaries consist of the V-O relations were built and evaluated by software developers. Evaluation result confirms that the relations in the dictionaries are adequate. 1. は じ め に