Accessory minerals of columbite and microlite groups were identified in granitic pegmatite dike intruded into parental Carboniferous (~350 Ma) leucogranites of the crystalline basement of the Tatric Unit, Central Western Carpathians. The pegmatite is situated on E slope of Bystrý Hill near Liešťany village, the Strážovské vrchy Mts., Slovakia. Primary columbite-(Fe) forms euhedral crystal (~3 mm across) with diffuse internal zoning reflecting a relatively small compositional variations: Mn/(Mn + Fe) = 0.40 - 0.45 and Ta/(Ta + Nb) = 0.21 - 0.24. Secondary anhedral domains of Ta-rich columbite-(Fe) to tantalite-(Fe) (≤200 μm) with Mn/(Mn + Fe) = 0.45 - 0.47 and Ta/(Ta + Nb) = 0.45 - 0.62 partly replace primary columbite-(Fe) along crystal rims. Moreover, secondary subhedral crystals of microlite-group minerals (≤25 μm) form fracture fillings in columbite-(Fe). The microlites show uniform high Ta/(Ta + Nb) ratio (0.77 - 0.80) and U content (7.7 - 10.2 wt.% UO2; 0.18 - 0.21 U apfu) but different contents of F, Ca, Na and Pb: central parts locally show fluorcalciomicrolite composition (~2 wt.% F, ~9.5 wt.% CaO, 2.2 - 2.7 wt.% Na2O), whereas main microlite mass forms zero-valent-dominant microlite with inclusions (≤8 μm) of Pb-rich zero-valent-dominant microlite (16.8 - 19.7 wt.% PbO; 0.46 - 0.56 Pb apfu). Textural relationships and chemical compositions of Nb-Ta minerals indicate primary magmatic origin of columbite-(Fe) and post-magmatic (early subsolidus to late hydrothermal) formation of secondary Ta-rich columbite-(Fe) to tantalite-(Fe) and microlite-group minerals.


Investment in schooling is central to enhancing excellence in education and in turn productivity. This paper provides new evidence questioning the unconditional superiority of any private schools from a national school-leaving examination database of Nepal. Using IV identification strategy to minimise the selectivity bias of school choice, we compare student performance in heterogeneous private schools in pooled cross-sections, subject fixed effects and value-added models over time, with a view to assess their absolute as well as relative efficiency reflecting the value for money spent per student. It is the not-for-profit trust-run private schools that outperform others because they invest more in teaching and learning related infrastructure, thus highlighting the benefits of social motivation for private provision of schooling. As expected, the full sample results are driven by the results for the urban areas where it is easier for trust school to enhance excellence by hiring good teachers as well as ensuring efficient utilisation of good teachers through greater parental involvement. While profit can be good driver of private investment in starting new schools, it may fail to generate high test scores over longer time horizon. Undoubtedly, the quality of education matters which is unlikely to be sustained by the profit motive alone.


Based on available operational flight data of a Boeing 737-300 with CFM56-3 engines, four different thrust models are developed in MATLAB. The model development is supported by the software GasTurb which is able to compute operating lines for engine components based on a design point. The results are used for the generation of lookup tables. The computed thrust is then utilized in parameter estimation for the landing phase from touchdown to a calibrated airspeed of 50kts. Here, zero drag coefficients, spoiler drag coefficients and a braking coefficient are estimated for about 1500 flights using the Output Error Method combined with the Gauss-Newton algorithm.


In this issue of Arthritis and Rheumatology, McCormick and colleagues report how biologic disease-modifying anti-rheumatic drug (bDMARD) prices increased in Medicare and Medicaid from 2012-2016.(1) These novel data are gleaned from the Center for Medicare and Medicaid Services' drug pricing dashboard, which began publicizing year-over-year price changes on May 15, 2018.(2) That week, health policy advocates like myself1 perused the dashboard and saw an alarming trend. bDMARD prices appeared to be rising faster in Medicare Part D (the distribution system for drugs that patients self-administer) than in Part B (drugs given in the office or infusion center).


The paper describes the architecture of the information expert system designed and dedicated to stock exchange data processing, analyzing and presentation. The system uses Artificial Neural Networks (ANN) combined with technical analysis and fractal analysis to predict future price of stock exchange assets. It also enables selection of companies, which assets will be increased. The selection of companies is based on comparing algorithms implementing Hopfield network. The system displays a list of the companies with the highest expected profit sorted in descending order.


Objectives The present study aimed to investigate the prevalence of central obesity among adults with normal BMI and its association with metabolic diseases in Jilin Province, China. Methods A population-based cross-sectional study was conducted in 2012 in Jilin Province of China. Information was collected by face to face interview. Descriptive data analysis and 95% confidence intervals (CI) of prevalence/frequency were conducted. Log-binomial regression analyses were used to find the independent factors associated with central obesity and to explore the adjusted association between central obesity and metabolic diseases among adults with normal BMI. Results Among the adult residents with normal BMI in Jilin Province, 55.6% of participants with central obesity self-assessed as normal weight and 27.0% thought their body weight were above normal. 12.7% of central obesity people took methods to lose weight, while 85.3% didn't. Female, older people and non-manual worker had higher risk to be central obesity among adults with normal BMI. Hypertension, diabetes and hyperlipidemia were significantly associated with central obesity among adults with normal BMI, the PRs were 1.337 (1.224–1.461), 1.323 (1.193–1.456) and 1.261 (1.152–1.381) separately when adjusted for gender, age and BMI. Conclusions Hypertension, diabetes and hyperlipidemia were significantly associated with central obesity among adults with normal BMI in Jilin Province, China. The low rates of awareness and control of central obesity among adults with normal BMI should be improved by government and health department.


Abstract: Plastic waste is a vital solid waste due to its un-decaying properties with respect to time, but plastic waste has interlocking properties that lead to enhancing the interlocking properties of the concrete. Self-compacting concrete is concrete with high workability and does not need vibration it is good for complex structural elements. So high-strength concrete production becomes typical but the interlocking properties of the plastic waste can be given a suitable direction for the strength parameter of self-compacting concrete. The major plastic waste source at the site is the cement plastic bags, cement bags are made of polypropylene polymer therefore they cannot react with cement, but are fibrous in nature and perform good interlocking properties.


The principal author is grateful to the National Maternity Hospital and the Irish Hospice Foundation for providing finance towards this MSc research study.


Analytical studies of the effects of power on flow instability in parallel channels have predicted that the Ledinegg flow instability, encountered as flow is decreased for typical operating power levels, would not be experienced at low power. These predictions indicate that at low power, the buoyancy effect is significant and may be greater than the friction loss effect. For a system in which the flow of coolant is upward, the increased buoyancy enhances flow in the channel. Under these conditions, as the flow rate is reduced and the void increases, the overall pressure loss decreases. That is, the demand curve turns downward (Fig. 1). Under this condition, flow instability does not occur. This testing was performed to confirm the predicted behavior and to provide data for benchmarking of computer codes used for predicting the performance of reactor fuel elements.


Background: MR spectroscopy examines molecules like hydrogen ions and protons. The technique of proton spectroscopy is more commonly used. Metabolites, or metabolic products, come in a variety of forms. The aim of this work is to evaluate the role of MR spectroscopy in diagnosis of infants and children presented with developmental delay.
Methods: This study was carried out on 30 children presented with developmental delay aged between 3 months to 12 years referred for brain MR spectroscopy for diagnosis of delay in milestones. All patients were subjected to: Full history, clinical examination, some patients need I.Q testing and MRS assessment.
Results: There was no significant difference in N-acetyl-aspartate/creatine and Cho/Cr ratios in cases ≤ 2 years between the study group and the control group. N-acetyl aspartate/creatine ratio in cases >2 years was significantly lower in the study group patients than that of control   group P<0.05. Cho/Cr was significant increase in study group compared to control group (p< 0.05).
Conclusions: the proton MR spectroscopy can be used to diagnose and follow developmental delay especially in children more than two years as we found typical changes in NAA/Cr and Cho/Cr.


This paper describes the current status of the international standard ISO 10303 (STEP) in respect of its capabilities for the capture and exchange of history-based parametric CAD models. The primary resources needed are all now available, and the necessary implementable part of the standard will shortly be in place for use by translator developers.


Extracting the process planning information from the CAD data is the key issue in integrated CAD/CAM system. In this paper, we develop algorithms for extracting the shape and setup configuration for NC machining of prismatic parts. In determining the workpart shape, the minimum-enclosing concept is applied so that the material waste is minimized. To minimize the number of setups, feature based algoritm is developed considring the part shape, tool shape, and tool approach direction. The validity and effectiveness of the developed algorithms were tested by computer simulations.


Polystyrene-supported N-phenyl-N-acyl sulfonamide resin was prepared by reacting polystyrene sulfonyl chloride resin with aniline and acylating in pyridine with either acid chlorides or anhydrides. Then, this resin was utilized as a new type of acyl transfer reagent to synthesize the amide library. It was approved to be a more effective acyl transfer reagent with higher amide yields than the polystyrene-supported N-methyl-N-acyl sulfonamide resin and N-benzyl-N-acyl sulfonamide resin. When the phenyl group bonded to the N atom on N-phenyl-N-acyl sulfonamide resin was substituted by the electron withdrawing group or electron donating group, a decreasing amide yield was obtained. N-phenyl-N-acyl sulfonamide resin could be regenerated many times.


In district-based electoral systems where party discipline is strong, it makes sense for parties to direct monetary and rhetorical appeals to swing districts in order to maximize electoral success for the party as a whole, whereas weak parties may be controlled by an incumbency cartel that rewards core constituencies in home districts in order to retain existing seats even at the expense of the party's total seat share (Stokes 1967; Butler and Stokes 1974; Cox 1987; Weingast 1979, 1994; Weingast, Shepsle and Johnsen 1981; Carey and Shugart 1995; McGillivray 1997, 2004; Remington and Smith 2001). But even parties with strong enough discipline to rein in incumbency protection run into complex calculations of optimal targeting when voters within and across districts are heterogeneous with respect to preferences, intensity of preferences, and mobilizational capacity (Bradbury and Crain 2005; Morgenstern and Potthoff 2005). Single issue voters signal clear voting intentions, and the strong gravitational pull that internally homogeneous districts exert on their representatives works at cross purposes with Japan adopted new, largely majoritarian, electoral rules in 1994 that have begun to reshape the political landscape in dramatic ways. The old rural-urban divide between the parties that seemed to characterize Japanese politics in fact masked a strategy of relying on groups in society that could be easily mobilized and monitored for purposes of allocating the vote among multiple candidates in most districts. Under the new rules, programmatic appeals are a more efficient way to gain a plurality of voters, leaving the old mobilizational strategy in disarray and consequently put and end to the LDP's long-term dominance. We speculate that clientelistic transactions between voters and politicians continue to decline because, given the system's majoritarian electoral incentives, rebundling rural protectionism with the social insurance concerns of the urban poor will be more ideologically consistent and therefore electorally more efficient.


The aim of this project is to assess whether the fundamentals of irreversible thermodynamics, and in particular the notion of entropy generation, are valid to characterize induced damage due to the capacitive elements of the energy injected to the condenser does not dissipate heat that degrades the component. First, there is a presentation of the general theory of thermodynamics and entropy concept and a brief explanation of how electronic component capacitor. It then describes the experimental method used, all materials used in assembling the bench tests, the system and the data acquisition program developed to collect them. Have evaluated the data with measurements made in testing and have been drawn conclusions that confirm the theory of entropy generation is a valid method to characterize the damage induced by capacitive elements of the injected energy capacitor that does not dissipate heat that degrades the component. Finally, a detailed budget for materials and labor of this project is presented and a proposal is made for possible future studies as a continuation of this project.


Purpose: We explore how multiple facets of board diversity influence technical efficiency and total factor productivity.

Methodology: We measure board diversity in two dimensions: relation-related dimension (age and gender) and task-related dimension (tenure, education, and expertise). We employ a balanced panel data of 806 non-financial Chinese firms over the period 2009 to 2017. We use a two-stage approach for analysis. In the first stage, we use a non-parametric frontier approach to calculate the technical efficiency and factor productivity scores. In the second stage, we regressed these scores on board diversity attributes (relation-related diversity and task-related diversity).

Findings: By employing Tobit regression and two-step system GMM, we find that board diversity improves technical efficiency and total factor productivity. Our analyses illustrate that a higher diversity on corporate board (in terms of age, gender, tenure, education, and expertise) positively influence firm efficiency.

Implications: Our findings have important implications for policymakers. We suggest that regulators should devise policies to encourage board diversity. Because a diverse board can bring knowledge, skills, abilities, expertise, and experience of diverse group members, which will ultimately enhance a firm's efficiency. Especially, in the emerging markets (like China), there is still need for standard governance mechanisms, therefore we suggest that policymakers should develop regulations and promote diversity of directors, as one of the factors for improving the governance mechanisms, which will ultimately improve firms productivity.

Originality/Value: Prior studies mostly considered only one dimension (such as gender) of diversity, and therefore have overlooked how other dimensions influence firms. We consider several dimensions of diversity and quantify them into relation-related (age and gender) and task-related (tenure, education, and expertise) attributes, and show how they influence firms' efficiency. To the best of the authors' knowledge, this is the first study to comprehensively investigate how several facets of diversity influence a firm's technical efficiency and total factor productivity.


Recently, several schemes have been proposed for IP traffic source identification for tracing attacks that employ source address spoofing such as denial of service (DoS) attacks. Most of these schemes are based on packet marking (i.e., augmenting IP packets with partial path information). A major challenge to packet marking schemes is the limited space available in the IP header for marking purposes. In this paper, we focus on this issue and propose a topology based encoding schemes supported by real Internet measurements. In particular, we propose an idealized deterministic edge append scheme in which we assume that the IP header can be modified to include the marking option field of fixed size. Also, we propose a deterministic pipelined packet marking scheme that is backward compatible with IPv4 (i.e., no IP header modification). The validity of both schemes depends directly on the statistical information that we extract from large data sets that represent Internet maps. Our studies show that it is possible to encode an entire path using 52 bits


The issue of rational nutrition of children is still extremely relevant and an effective factor ensuring the preservation of life and health of children. Pathological conditions associated with intolerance to certain components of food are increasingly common. When assessing the chemical composition of experimental samples of goat meat (Zaanen, Alpine, Nubian), no abnormal deviations were detected, and all indicators were in the generally accepted contents of this type of animal muscle tissue. Comparative analysis of goat meat samples shows that the fat content is more than 3 times less than that of lamb. The mass fraction of moisture is higher than mutton by 3 - 5%. Thus, it confirms that goat meat is a more dietary meat raw material in comparison with lamb. The potassium content among the experimental samples is distinguished by the goat meat of the Nubian breed (4125.83 ± 618.87 mg/ kg), which in comparison with the Zaanen (2470.10 ± 370.52 mg/kg) is more than 1.5 times greater, and the Alpine breed (1693.22 ± 253.98 mg/kg) is more than 2 times. The concentration of such essential amino acids as tryptophan, leucine, isoleucine, phenylalanine, methionine allows you to cover from 14% to 30.5% of the daily norm.


Weightlifters compete in the snatch, clean and jerk, and total (snatch + clean and jerk). Commonly used assistance exercises for training weightlifters are front barbell squats and back barbell squats. The purpose of this study was to determine relationships between the front barbell squats and back barbell squats one repetition maximum (1 RM) and the snatch, clean and jerk, and total 1 RM. Senior male competitive weightlifters (n = 72) served as subjects in the survey. Significant correlations were found between front barbell squats and snatch, clean and jerk, or total 1 RM (r2 = 0.85, 0.88, and 0.87 respectively) and between back barbell squats and snatch, clean and jerk, or total 1 RM (r2 = 0.83, 0.84, and 0.83 respectively). Regression analyses indicate that 1 RM in the snatch, clean and jerk, and total are linearly related to the 1 RM in the front barbell squats and back barbell squats. Superior lifters appeared to be more efficient in using their back barbell squats strength during weightlifting compared to lower level lifters.


In 1985, seven years before Derek Walcott was awarded the Nobel Prize in Literature, Sven Birkerts hailed the Caribbean poet as a prodigious talent. Expressing admiration for his literary 'craftsmanship', Birkerts concluded a review of Walcott's work by suggesting that this poet's evident ability might prompt a reconfiguration of assumptions about dominant literary realms. 'He is the outsider', Birkerts asserts, 'the poet from the periphery, but it may be time to centre the compass at his position and draw the circle again'. 1 Throughout the review, Birkerts uses tropes of 'periphery' and 'centre' to clarify his opinion of Walcott's capacity to 'redraw' conventional Western assumptions about literary boundaries. However, although he proposes a radical re-centring of the literary 'compass' in order to position Walcott as the focal point of a prestigious 'circle' of literary excellence, Birkerts's comments do not challenge the idea of a literary sphere divisible into cultural and economic 'centres' and 'peripheries'. Instead his analysis clings to the conventions of what Timothy Brennan has called a 'centre/periphery model' 2 of world literary space, promoting a perception of the Caribbean region as external to established systems for the production and appreciation of literary works, while portraying Walcott as a figure whose unusual talent might allow him to transcend the perceived limitations of his region and emerge as a new 'centre' on a world literary stage. Birkerts's characterization of Derek Walcott as a 'central' poet from a 'peripheral' region provides a conceptual starting-point for this article, which considers how conventional perceptions of Walcott's status as a public literary figure relate to the portrayal of economically marginalized communities and canonical literary traditions in his poetry. Comparing the rhetoric surrounding Walcott's receipt of the Nobel Prize in 1992 with the portrayal of ideas about 'centre' and 'periphery' in his widely


A kind of three-dimensional(3-D)sound ray tracing algorithm in heterogeneous media is studied.This algorithm includes two steps:wavefront traveltimes computation forward and sound ray tracing based on wavefront traveltimes backward.In forward step,we found on Eikonal equation and use GMM(Group marching method)wavefront marching method based on level set to compute wavefront traveltimes on discrete grid points step by step,beginning with sound source.In backward step,sound ray tracing is proceeded from receiver to each cell towards sound source in steps, with wavefront traveltimes computed in the forward step.Wavefront traveltimes on arbitrary positions in each cuboid cell can be expressed with linear interpolating function about wavefront traveltimes on grid points of the same cell.And so an algorithm of 3-D sound ray tracing in heterogeneous media is put forward.The simulation results indicate that this method can improve both precision and efficiency of 3-D sound ray tracing greatly.


Iron is unstable as an oxygen evolution electrode in alkaline media. Thus, relatively expensive nickel-based electrodes are used in industrial alkaline water electrolysis. We show that an iron substrate can be rendered stable and electrocatalytically active for the oxygen evolution reaction by nano-scale surface modification with nickel. The electrocatalytic activity of such a surface-modified iron electrode is comparable to the recently-reported nickel-based catalysts. The electrocatalytic activity is due to a 50-nanometer layer of a high-surface area α -nickel hydroxide on the iron electrode. The nickel modification renders the iron electrode electrically- conductive, prevents dielectric breakdown, and thus endows anodic stability. The electrocatalytic activity is unchanged even after 1000 hours of continuous operation. The temperature of preparation is critical, as excessive dehydration of the hydroxide layer results in nickel ferrite formation and a drastic reduction in electrocatalytic activity. We report significant insight into the surface chemical composition and structure of the catalyst layer by X-ray Absorption Spectroscopy, Photoelectron Spectroscopy, and Transmission Electron Microscopy. Electrochemical kinetics analysis suggests that surface hydroxo-intermediates react with the hydroxide ions from the solution to evolve oxygen. Thus, the surface-modified iron substrates present an opportunity for improving the performance and reducing the cost of alkaline water electrolysis systems.


Abstract Trimethylsilanolate alkali salts are widely used in organic synthesis, mainly due to their solubility in common organic solvents. They are frequently used as nucleophiles in ester hydrolysis, both in solution and solid-phase chemistry. However, they have also been used as mild bases or as specific reagents in some chemical transformations. Reactions employing trimethylsilanolate alkali salts as the key component are typically performed under mild reaction conditions. This review summarizes the utilization of trimethylsilanolate alkali salts in various organic transformations. 1 Introduction 2 Properties of Alkali Metal Trimethylsilanolates (TMSO[M]) 3 Trimethylsilanolate Alkali Salts in Organic Synthesis 4 Conclusion


The patient was 64-year-old female who presented with complaints of a lower abdominal mass. A total abdominal hysterectomy, bilateral salpingo-oophorectomy, pelvic lymphadenectomy and omentectomy were performed. Histological findings of a characteristic arrangement of spindle-shaped cells and diffusively positive immunohistochemical staining for h-caldesmon confirmed a pathological diagnosis of left ovarian leiomyosarcoma. J Clin Gynecol Obstet. 2018;7(1):26-29 doi: https://doi.org/10.14740/jcgo477w


Indonesia has a lot of tourism area, one of them is in NTB Province namely Lebo 'Taliwang West Sumbawa Regency, furthermore this research aims to know the potential and development effort of tourism object around Lebo' Taliwang of West Sumbawa regency. Analyzer used is SWOT which is used to know the development effort of Lebo Taliwang Lake tourism object. The SWOT analysis shows that there are several strengths, weaknesses, opportunities, and threats from Lebo 'Taliwang lake tourism object.


Case presentation Prolidase enzyme plays a crucial role in proline-rich proteins metabolism and physiological processes such as inflammation, cell proliferation, wound healing, angiogenesis, and carcinogenesis. Due to mutations in the peptidase D (PEPD) gene, the catalytic activity of prolidase loss results in prolidase deficiency. Deficiency of prolidase enzyme is an autosomal inborn metabolic rare genetic disorder that has neither any proper treatment nor consensus for treatment. With approximately 100 cases recorded worldwide, the submitted manuscript describes the 2nd recorded case of prolidase deficiency, an extremely uncommon autosomal recessive disorder associated with collagen metabolism, in a 15-year-old Pakistan boy. The disorder typically becomes apparent during infancy. Affected individuals may have enlargement of the spleen (splenomegaly); in some cases, both the spleen and liver are enlarged (hepatosplenomegaly). Diarrhea, vomiting, and dehydration may also occur. People with prolidase deficiency often develop skin lesions, especially on their hands, feet, lower legs, and face. The severity of the skin involvement, which usually begins during childhood, may range from a mild rash to severe skin ulcers. The severity of symptoms in prolidase deficiency varies greatly among affected individuals. Here we present the report of a 15-year-old boy who has all the clinical manifestations of deficiency of prolidase. This is the 2nd case in Pakistan's 229,488,994 million population.


Photovoltaic (PV) installations are typically optimized on the basis of simplified considerations that draw design conclusions from insolation data and heavily-averaged consumption trends (e.g. using daily averages) and/or standard consumption profiles. The analysis proposed herein begins with the premise of working on averaged time series data using much narrower time intervals (e.g. 1-hour series). Design of both the installed PV power and storage capacity (lead-acid battery technology for purposes of this article, yet the underlying principle remains applicable to any other technology) is optimized by incorporating accumulator cycling aging. The energy management strategy that serves, among other things, to reduce cycling costs (sizable in the case of lead-acid batteries [1]) can in turn be optimized according to this design procedure. The solid correlation between design and energy management functions is also taken into account herein. The objectives (optimization criteria) considered in this approach are not limited to the classical notion of financial costs, but instead encompass environmental energy costs as well (Global Energy Requirement, or GER), in addition to the rate of consumer satisfaction (load shedding has been envisaged).


The mechanism and influencing factors and practices of both enhanced coagulation and optimized coagulation are discussed and analyzed.To strengthen and optimize the step of coagulation in conventional water treatment can help to promote the water quality with low cost.At the same time,several items on coagulation process are pointed out to be paid attention in real production process for water supply plant.


Data compression is the process of reducing redundancy in data representation in order to achieve savings in storage and communication costs. It is a popular approach to reducing data volumes to lower disk utilization and reduce network traffic, hence reduce data transfer times in distributed computing. The research paper is presented and focused on the significant of using data compression in networking as well as its different types of image compression techniques. They are lossless and lossy image compression methods. It explores comparison for some image format such as jpeg, tiff, bmp, png, included algorithms for each formats, each format such as jpeg2000, and the methods are described in details with using figures. It shows the coding types and categories s such as DPCM, entropy coding, Huffman coding, arithmetic coding, LZW.


The economic scenario in India has undergone considerable change in the last few decades. Some of these changes include deregulation of the banking industry, development of financial markets, transition into floating exchange rates, increasing role of capital markets and global competition. There are two types of risk, namely, market risk or systematic risk, and company risk or unsystematic risk. The Capital Asset Pricing Model (CAPM) which was developed by Sharpe (1964), Lintner (1965), and Black (1972) was largely supported by Black, Jensen and Scholes (1972), Fama and Macbeth (1973) and Blume and Friend (1973). Later this method was questioned on various grounds. The paper mainly focuses on the estimation of NIFTY quoted companies (one of the NSE, India index) returns for the period of 1997-2010 using the CAPM frame work. Further this paper compares the CAPM returns with that of the Annual Market Returns (AMR). The study states that most of the companies' scrips are undervalued and have not rewarded the investors properly.


The formation of mixed crystals in equimolar KCl-KBr powder mixtures is studied at temperatures from 406 to 602°C. The progress of the homogenization is followed by measuring the change in specimen capacitance as a function of time. The results indicate that the following three processes are involved in the mixed crystal formation: (i) grain boundary diffusion, (ii) volume diffusion of Cl− ions, and (iii) volume diffusion of Br− ions. The experimental results for the activation energies associated with these processes are respectively 1·5±0·2 eV, 1·9±0·2 eV and 2·1±0·1 eV.


Immunotherapy encompasses a wide array of treatment modalities that utilize our natural defense system to fight against cancer and in recent years has contributed to significant improvement in survival and quality of life in patients. However, its use in prostate cancer has been limited due to low efficacy and lack of effective biomarkers. Prostate cancer's unfavorable tumor microenvironment characterized by T-cell exclusion and expansion of T-reg cells, along with the possible inhibitory effect of androgen deprivation therapy (ADT) on the immune system further explains this poor response to immunotherapy. Here, we review current immunotherapies and ongoing clinical trials as well as potential biomarkers being investigated to predict treatment responses to immunotherapy. Finally, we discuss the conflicting results on the best approach to sequencing immunotherapy in relation to ADT.


COPYRIGHT © 2022 Motto Ros, Demarchi and Carrara. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Editorial: Smart dust: Micro and nano scale devices for highly-integrated localized and distributed smart systems for precision and personalized medicine


The utility model discloses a punching tool of a forklift connecting workpiece. The punching tool comprises upper mould seats and a lower mould seat. An upper mould plate is fixedly connected below the upper mould seats. The lower mould plate is fixedly connected above the lower mould seat. The upper mould seats are fixedly connected with the upper mould plate through screw rods in serial connection. Stroke guide rods are arranged on the upper mould seats. The stroke guide rods are connected with the upper mould seats in series. Stroke holes are formed in the corresponding positions of the lower mould plate opposite to the upper mould plate. The stroke holes are matched with the stroke guide rods. A plurality of punch needles are fixedly arranged on the upper mould seats. Punch needle holes are formed in the positions, corresponding to the positions of the punch needles on the upper mould seats, of the upper mould plate and the lower mould plate. The punch needle holes are matched with the punch needles. Replacing elastic blocks are fixedly arranged between the upper mould seats and the upper mould plate. The punching tool of the forklift connecting workpiece carries out one-time hole punching on the forklift connecting workpiece, convenience and quickness are achieved, labor force is saved, punching is accurate, pass rate is high, and production cost is lowered.


Natural disasters, human errors, and technical issues have caused disastrous blackouts to power systems and resulted in enormous economic losses. Moreover, distributed energy resources have been integrated into distribution systems, which bring extra uncertainty and challenges to system restoration. Therefore, the restoration of power distribution systems requires more efficient and effective methods to provide resilient operation. In the literature, using Q-learning and multiagent system (MAS) to restore power systems has the limitation in real system application, without considering power system operation constraints. In order to adapt to system condition changes quickly, a restoration algorithm using Q-learning and MAS, together with the combination method and battery algorithm is proposed in this study. The developed algorithm considers voltage and current constraints while finding system switching configuration to maximize the load pick-up after faults happen to the given system. The algorithm consists of three parts. First, it finds switching configurations using Q-learning. Second, the combination algorithm works as a back-up plan in case of the solution from Q-learning violates system constraints. Third, the battery algorithm is applied to determine the charging or discharging schedule of battery systems. The obtained switching configuration provides restoration solutions without violating system constraints. Furthermore, the algorithm can adjust switching configurations after the restoration. For example, when renewable output changes, the algorithm provides an adjusted solution to avoid violating system constraints. The proposed algorithm has been tested in the modified IEEE 9-bus system using the real-time digital simulator. Simulation results demonstrate that the algorithm offers an efficient and effective restoration strategy for resilient distribution system operation.


Therapeutic interventions to eradicate latent HIV in ART-treated infection have yet to show efficacy. We used a systems biology approach to identify a subset of ART-treated individuals with immune-dysfunction that had the highest frequencies of cells with inducible HIV. Contrary to the prevailing notion that immune activation drives HIV persistence, blood from these individuals was enriched in senescence-inducing genes (high FOXO3, SMAD2 and IRF3), Treg frequencies and TGF-β signaling expression. In these "Senescent-INRs", high Firmicute phylum plasma nucleotides and butyrate/bile acids (like a-ketobutyrate) correlated with Treg frequencies and inducible HIV levels. Stimulation of naive CD4 T-cells with a-ketobutyrate led to TGF-β producing Treg differentiation, and PD-1 up-regulation on less differentiated cells. A dose dependent increase in latent HIV-infected memory CD4 T-cells was observed after TGF-β stimulation. Senescence cascades identified here can be targeted by PD-1/TGF-β specific interventions that have shown safety/efficacy in cancer, and can be crucial for HIV eradication.


FIELD: process engineering. SUBSTANCE: invention relates to blades for thermoplastic polymer pelletising and to method of their sharpening. Said blade is made from tool steel for cold machining with hardness making at least 65 units in Rockwell C-scale. Prior to fitting in pelletiser, said blade is heated treated at 500-700°C for over 5 minutes at the rate equal to or lower than 15°C/min. Blades are sharpened by abrasion against extrusion head plate surface. Force acting on blade at pressing it against plate surface does not exceed 0.5 N. Simultaneously, cooling is performed by circulating thermostatic fluid at variable flow rate. EFFECT: higher quality of cutting, lower wear rate. 10 cl, 4 dwg, 2 tbl, 6 ex


Abstract : Prior to 2003 the Army managed the flow of personnel into and out of units on an individual basis, which resulted in persistent personnel turnover throughout the year. This steady source of personnel turnover is assumed to undermine unit effectiveness by disrupting unit training proficiency and unit cohesion. In 2003, the Army began transitioning from an individual replacement system to a personnel management system called lifecycle manning. Lifecycle manning increases personnel stability by assigning approximately 3500 soldiers to a brigade combat team at the beginning of a three-year training and deployment cycle. These soldiers remain with the brigade for the entire cycle, thereby enabling teams to train together and develop high unit cohesion prior to deployment. The lifecycle manning policy is based on an assumed causal linkage where personnel stability leads to higher unit cohesion that leads to increased unit effectiveness. This dissertation empirically tests this assumption by analyzing the direct relationship between personnel stability and unit effectiveness without incorporating cohesion. The analysis applies production function theory with the factor input of interest being increased personnel stability and a production output of unit effectiveness. Using new measures of personnel stability and training proficiency scores from previous RAND research, this research assesses whether battalions with stable leadership achieve higher levels of training proficiency. The analysis results do not show a prevalent or strong relationship between battalion leadership stability and battalion training proficiency. This unexpected result potentially calls into question whether the transition to lifecycle manning should continue in its current form. The research also identifies other policy alternatives for improving unit effectiveness and raises questions about the cost-benefit analysis of implementing lifecycle manning.


Learning model is a whole series of teaching material presentation which includes all aspects before and after learning. The problem in this study is that student learning outcomes are still lo and lacking enthusiasm in the learning process, where the value of student learning outcomes is still much below the KKM. This type of research uses PTK, with a quantitative data collection in the from of student learning outcomes tests and qualitative data obtained from intervies and studend documentation data. With 23 students as research subjects. Based on the results of this study, the average cognitive score of srtudentd in cycle I was 73. In the first cycle the average cognitive score of students II was 82, so there was an increase of 9%. So the application of the RCCDE learning model can improve students learning outcomes in the material of interaction of living things with the environment so that it can help in the student learning proses.Keywords: RCCDE model, learning outcomes, the interaction of living things with the environment


Augmented reality techniques have been increasingly employed in the textile and fashion industry as well as computer graphics sectors. Three-dimensional virtual clothing CAD systems have also been widely used in the textile industries and academic institutes. Motion tracking techniques are grafted together in the 3D and augmented reality techniques in order to develop the virtual three-dimensional clothing and fitting systems in the fashion and textile industry sectors. In this study, three-dimensional virtual clothing sample has been prepared using a 3D virtual clothing CAD along with a 3D scanning and reconstruction system. Motion of the user has been captured through an RGB-D sensor system, and the virtual clothing fitted on the user`s body is allowed to move along with the captured motion flow of the user. Acutal fabric specimens are selected for the material characterization. This study is a primary step toward building a comprehensive system for the user to experience interactively virtual clothing under real environment.


The paper focuses on U.S. foreign investment. Part I notes its trivial impact on returns to U.S. capital and considers its greater importance for five industry groups. Part II reviews the economic advantages accruing to U.S. citizens from interventions in Panama and Cuba. Part III, the bulk of the paper, asks what impact U.S. foreign investment had on Latin American factor returns. It finds no evidence in the anti-imperialist literature for the assertions that such investment cut labor incomes or landowners' capital gains in these nations. It suggests that a struggle between two groups of capitalists, native and foreign, was more central to the economic aspects of "imperialist" conflict.


Dengue outbreaks threaten the stability of national health systems worldwide. Every year, late detection and inadequate response mechanisms compound the effects of rapid dengue transmission. Although outbreak alert indicators exist, the means to deploy them in early warning systems is often lacking.

Within this context, a programme led by TDR, the Special Programme for Research and Training in Tropical Diseases, conducted multi-country research into alarm signals for outbreaks and their use within early warning systems. In line with the prevailing literature, alarm variables such as probable dengue cases, mean temperature (and, to a lesser extent, rainfall and humidity) all evidenced predictive abilities. However, it was clear that countries lacked the requisite skills and resources to deploy these alarm signals in a predictive, operational way. It was on this basis that an accessible, adaptable and user-friendly early warning system was developed.

The aim of the Early Warning and Response System (EWARS) for Dengue Outbreaks: operational guide is to provide programme managers with a user friendly tool that can: (i) analyse and draw conclusions from historic dengue datasets; (ii) identify appropriate alarm indicators that can sensitively and specifically predict forthcoming outbreaks at smaller spatial scales; and (iii) use these results and analyses to predict and build an early warning system to detect dengue outbreaks in real-time. Together, these three components build technical capacity and provide a standardized methodology for predicting dengue outbreaks in countries where skills and resources are currently constrained.

This guide was produced by TDR together with the World Health Organization's Neglected Tropical Diseases (WHO/NTD) and WHO regional offices in the context of a European Union-financed research programme, the International Research Consortium on Dengue Risk Assessment, Management and Surveillance (IDAMS), to develop an evidence-based, early warning system for outbreak detection and management of dengue fever outbreaks.


We present a study of the transient onset of lasing and ultrashort pulse formation in a 1-μm InGaAs/GaAs quantum well (QW) vertical-external-cavity surface-emitting laser (VECSEL) that is mode-locked using an intracavity semiconductor saturable absorber mirror. The intra-cavity power build-up transient is observed following modulation of the laser mode in the cavity. Measuring the rise of the frequency-doubled laser output with respect to the fundamental allows determination of mode-locking onset times and pulse-shortening per round trip. A grating monochromator has been used to resolve the optical spectrum of the fundamental intracavity radiation during pulse formation. Combining both measurements we can begin to provide a comprehensive description of pulse formation in VECSELs.


This study is focused on the influence of friction time on the microstructure and the hardness values of butt  welded dissimilar pure copper/brass alloy pipes by continuous drive friction  welding. Five variation of friction times were applied during the welding processes. The joint were evaluated by microstructural analysis  and microhardness measurements. The results show that three distincs region were observed.  The grain formation in the three regions were revealed.  It was found that the hardness of the joints especially in HAZ regions were lower than that of the copper and brass base metals, while the hardness of the TMAZ region was higher than that of the copper base metal and the brass base metal. The microhardness values in the TMAZ  increased  with increasing the friction time up to 30 s and then decreased with incresing friction time.


Because the blues in the Delta region in the northwest corner of Mississippi is so much a part of the region's oral culture, little about it has the appearance to historians of being known for certain. As a result, many presentations of Delta blues history have had to rely on much that some readers may take as speculation, folktale, even myth. Whatever failings as history that Robert Palmer's Deep Blues (New York: Viking, 1981) may have had, Palmer did attempt to "fight fire with fire," that is, to address a few myths not with facts, but with new myths of his own. That W. W. Norton has published a book on Delta blues is not surprising, since it has published in three editions one of the key books about African American music, Eileen Southern's Music of Black Americans (1971; 1983; 1997). But what sort of book is Gioia's Delta Blues? His previous books include three volumes on jazz (especially The History of Jazz [New York: Oxford University Press, 1997]), and his 2006 Duke University Press publications Work Songs and Healing Songs may be regarded as broadening his research scope. Studying the blues is a logical move from jazz studies, since jazz musicians use blues forms as bases of improvisation. Taking up Delta blues, despite its difficulties to historians because of its lack of written and notated documents, follows from Gioia's study of work songs because of the work-song phrasing of many pre-1942 ("pre-war") Delta blues singers. But his thesis that "[rock music] is the true final destination of the Delta sound" (p. 6) strikes me as out of step with his previous studies, and debatable in view of the very limited role that Delta blues played in blues overall during the early years of rock (1954–63) until British rock groups from 1964 on brought Delta styles to great prominence. While the stripped-down instrumentation (often a single guitar) lends to Delta blues a primitiveseeming sound, it does not mean necessarily that Delta blues has a primal function as the source of all blues—although it is tempting and very easy to think so. Historians have long been divided over whether blues began in the Delta and spread outward, or whether it developed across the South from Arkansas to Georgia. The first two chapters of Lawrence Cohn's Nothing But The Blues (New York: Abbeville Press, 1993) each present the opposing viewpoints of that debate: Samuel Charters ("Working on the Building: Roots and Influences," pp. 13–31) took the Deltacentric view, and David Evans ("Goin' Up The Country: Blues in Texas and the Deep South," pp. 33–85) thought blues was the result of the South as a whole. For the sake of his thesis, Gioia appears to be a Deltacentrist, on the side claiming that the blues—or at least the most influential of all blues styles—comes from the Delta. One need not be a Delta-centrist to relate the history of Delta blues; in fact, one may be better off not being one, so as to notice and discuss without bias the outside influences on Delta blues. One such example is Bessie Smith, whom Gioia mentions on pp. 40–42, but does not comment on her influence. Charlie Patton used her rendition of "Mountain Top Blues" for his 1929 Paramount record "Hammer [Hammock] Blues," and Son House and Skip James each took lyrics from her "Work House Blues" release for their own blues. Instead of a continuous narrative, Gioia uses a series of chapter-length portraits of individual musicians to relate his history. Those he singles out are W. C. Handy, Charlie Patton, Son House, Skip James, Robert Johnson, Muddy Waters, John Lee Hooker, Howlin' Wolf, and B. B. King. Palmer had followed a similar plan featuring most of the same musicians in Deep Blues, but he did not give whole chapters to Handy and James, and for the most part he combined his profiles of Hooker, Howlin' Wolf, and King into one chapter. Further more, in a final chapter, Gioia gives a AMERICAN MUSICS


The ancient civilisation of Mesopotamia arose on the alleged site of the Garden of Eden. When Rome was founded (traditionally in the 8th century BC), Nineveh was already 4000 years old. Babylon was at its zenith about the 7th-6th century BC.


In this paper we develop an economic asset pricing framework that identifies three key sources of risk that underlie the risk and return tradeoff in the economy: news to cashflows, news to expected returns, and news to aggregate volatility. A novel contribution of this paper is the inclusion of time-varying volatility news which has both important theoretical and empirical implications. Motivated by a Long Run Risk framework, we theoretically show that to consistently identify and explain the time series and cross sectional variation in risk premia it is essential to allow for time varying economic uncertainty in the model. Empirically, we show that the exposure of assets to volatility risk, sorted by size and book to market, line up vary well with those assets' average excess return in the data. The model's fit of a broad cross section of asset returns is about 90\% of which the volatility news factor contributes 20\%. The volatility component plays a significant role in explaining the level of the premium as well as the value and size spreads.


For the last two decades, we have seen a drastic development of modern cosmology based on various observations such as the cosmic microwave background (CMB), type Ia supernovae, and baryonic acoustic oscillations (BAO). These observational evidences have led us to a great deal of consensus on the cosmological model so-called ΛCDM and tight constraints on cosmological parameters consisting the model. On the other hand, the advancement in cosmology relies on the cosmological principle: the universe is isotropic and homogeneous on large scales. Testing these fundamental assumptions is crucial and will soon become possible given the planned observations ahead. Dipolar modulation is the largest angular anisotropy of the sky, which is quantified by its direction and amplitude. We measured a huge dipolar modulation in CMB, which mainly originated from our solar systems motion relative to CMB rest frame. However, we have not yet acquired consistent measurements of dipolar modulations in large-scale structure (LSS), as they require large sky coverage and a number of well-identified objects. In this thesis, we explore measurement of dipolar modulation in number counts of LSS objects as a test of statistical isotropy. This thesis is based on two papers that were published in peer-reviewed journals. In Chapter 2 [Yoon et al., 2014], we measured a dipolar modulation in number counts of WISE matched with 2MASS sources. In Chapter 3 [Yoon & Huterer, 2015], we investigated requirements for detection of kinematic dipole in future surveys.


The article is devoted to the development of communicative competencies in the process of learning foreign languages. This is expressed in the replacement of methods of presenting educational information with forms of communication between teachers and students and students among themselves, in increasing the level of students' independence in their educational activities, the process of communicative competencies life-practical situations, social and psychological trainings.


AbstractRecent studies have revealed that zyco-soil and nanosilica are among the nanomaterials that can help improve the moisture-damage resistance of asphalt mixtures. However, these also affect t...


A high-toughness marine engineering steel sheet and a manufacturing method, out belongs to the field of marine engineering steel. Weight percent chemical composition: C 0.03-0.08%, Si 0.10-0.30%, Mn 1.0-1.60%, Alt 0.03-0.04%, Nb 0.03-0.06%, V 0.05-0.09%, Ti 0.010-0.02%, Mo 0.1 -0.4%, Ni 0.1-0.4%, Cu 0.1-0.4%, P <0.01%, S <0.005%, Nb + V + Ti≤0.12%, the balance being Fe and unavoidable impurities. By adding a small amount of Ni, and with a reasonable controlled rolling and cooling processes, to ensure the low temperature toughness of the steel sheet, heat treatment process is omitted, reduce production costs, resulting 10-50mm steel sheet has good strength and ductility, weldability, resistance to tearing and lamellar drop hammer excellent mechanical properties and the like; and the process is simple, can be widely used fixed, the key parts and semi-submersible jack-up offshore platform.


As the world's largest carbon emission country, China has put forward the "double carbon" goal in order to better respond to climate change, and the development of green finance is an important measure to implement sustainable development and achieve the "double carbon" goal. This paper takes green finance under the background of "double carbon" as the research object, combines the current development of green finance in China, and summarizes the challenges faced by green finance in China from five aspects: institutional system, product innovation, carbon trading market mechanism, information disclosure, and risk assessment. Finally, according to the internal requirements of the "double carbon" goal and the basic national conditions of China, we propose solutions from the four dimensions of establishing a restraint and incentive mechanism, promoting product innovation, attaching importance to talent cultivation, and strengthening international cooperation, aiming at providing suggestions for the development of green finance in China.


Abstract Urban-regional economies are developing in highly variegated, uneven ways globally. In economic geography, studies of urban-regional development emphasize the prospects for innovative, globally-competitive industrial sectors to emerge and enhance a city-region's exchange value in global markets. This focus reflects a productivist bias that may fail to address issues related to the use-value of, or living conditions associated with urban transitions. Such concerns are particularly significant in the Global South where urbanization has often not led to socioeconomic transformations that benefit the majority of urban residents. To examine the relationships between a city's exchange and use value, this paper argues for a sociotechnical systems approach that conceptualizes cities as constituted by interdependent or coupled regimes related to production, consumption, and infrastructure that stabilize urban-regional economies and determine development pathways. The framework is deployed empirically to examine the case of Nairobi, Kenya – a rapidly growing urban-regional economy characterized by high rates of inward foreign direct investment, principally in speculative real estate ventures in the consumption regime. Domestic manufacturing industries (the production regime) are stagnating, struggling to compete against imports, and failing to generate widespread formal employment and raise tax revenues for the infrastructure regime. The net result is a city characterized by fragmented or splintered regimes that create highly uneven, exclusionary development outcomes. These dynamics and findings are analyzed in relation to a similar study of Dar es Salaam, Tanzania in order to demonstrate the comparative potential of this conceptual approach. The paper concludes with a call for economic geographers to better account for the use-value of urban-regional economies such that development concerns beyond production become more central to our analyses.


This paper illustrates how thermoelasticity theory can be used to analyze a rather simple type of phase transition involving a shear critical point.


The regularity theory of the Campanato space $\mathcal{L}^{(q,\lambda)}_k(\Omega)$ has found many applications within the regularity theory of solutions to various geometric variational problems. Here we extend this theory from single-valued functions to multi-valued functions, adapting for the most part Campanato's original ideas (\cite{campanato}). We also give an application of this theory within the regularity theory of stationary integral varifolds. More precisely, we prove a regularity theorem for certain \textit{blow-up classes} of multi-valued functions, which typically arise when studying blow-ups of sequences of stationary integral varifolds converging to higher multiplicity planes or unions of half-planes. In such a setting, based in part on ideas in \cite{wickstable}, \cite{minterwick}, and \cite{beckerwick}, we are able to deduce a boundary regularity theory for multi-valued harmonic functions; such a boundary regularity result would appear to be the first of its kind for the multi-valued setting. In conjunction with \cite{minter}, the results presented here establish a regularity theorem for stable codimension one stationary integral varifolds near classical cones of density $\frac{5}{2}$.


ABSTRACT In this paper, we propose a new approach to analyse the stability of a general family of nonlinear positive discrete time-delay systems. First, we introduce a new class of nonlinear positive discrete time-delay systems, which generalises some existing discrete time-delay systems. Second, through a new technique that relies on the comparison and mathematical induction method, we establish explicit criteria for stability and instability of the systems. Three numerical examples are given to illustrate the feasibility of the obtained results.


SIRS, We thank Dr. Yamamoto for his interest in our article, and for his letter regarding the role of granulocyte ⁄monocyte adsorptive apheresis in the management of ulcerative colitis. Although we agree with his general points regarding the possible benefit of granulocyte ⁄monocyte adsorptive apheresis in ulcerative colitis, in terms of remission rates and corticosteroid-sparing effects, most of these were observed in Japanese patients. The only sham-controlled study conducted in a Western population, to date, failed to demonstrate any clear benefit of therapy. We therefore feel that it is a little premature to speculate on the cost-effectiveness of this therapy in ulcerative colitis. As we stated in our article, what is actually required are convincing high-quality data that granulocyte ⁄monocyte adsorptive apheresis is effective in Western patients with ulcerative colitis.


Abstract Poster session 1, September 21, 2022, 12:30 PM - 1:30 PM Background There are limited oral treatment options for patients with high-mortality fungal infections such as candidemia or invasive candidiasis who fail currently available antifungals or have an infection caused by resistant organisms. Ibrexafungerp is an investigational broad-spectrum glucan synthase inhibitor with activity against Candida species, including azole- and echinocandin-resistant strains. A Phase 3 open-label, single-arm study of ibrexafungerp (FURI; NCT03059992) is ongoing for the treatment of patients intolerant of, or with invasive fungal disease refractory to, standard antifungal therapy. We present an interim analysis of all-cause mortality within 30 days post-treatment from the FURI study by fungal disease type for patients with candidemia or invasive candidiasis, who completed therapy up until October 2021. Methods FURI patients are eligible for enrolment if they have proven or probable: severe mucocutaneous candidiasis or invasive candidiasis, or candidemia, with documented evidence of failure, intolerance, or toxicity related to a currently approved standard-of-care antifungal treatment; or patients who cannot receive approved oral antifungal options (eg, due to susceptibility), and continued IV antifungal therapy is clinically undesirable or unfeasible. Patients were followed through 30 days post-treatment for all-cause mortality. Results Out of the 113 patients who completed therapy in the FURI study through October 2021, 56 (50%) had invasive candidiasis or candidemia and were treated with ibrexafungerp. The most common infections in this group were candidemia (15/56, 26.8%), intra-abdominal infection (13/56, 23.2%), and bone infection (10/56, 17.9%). Overall survival within 30 days post-treatment in this group of 56 patients was 94.6%. Of the 56 patients with candidemia or invasive candidiasis, three (5.3%) died within 30 days after completion of treatment with ibrexafungerp, a fourth died at 31 days, a fifth died at 50 days, and a sixth died at 56 days. The mean age of the expired patients was 56 years. All 4 patients had candidemia (3 with C. parapsilosis and 1 with C. albicans), and 2 had intra-abdominal candidiasis, (both with C. glabrata). The average time on therapy with ibrexafungerp was 15.7 days. The mean time to death post-treatment for these patients was 27 days (median, 21 days). In five cases, the deaths were due to causes other than the underlying fungal disease. For the other case, the cause of death was not disclosed. Conclusions Analysis of all-cause mortality in these patients from the FURI study indicates that oral ibrexafungerp provides a favorable therapeutic response in patients with challenging fungal diseases and limited treatment options.


To counter the function problems of profiling and roll-up spring machine, adopting PLC system, a new profiling and roll-up spring system is developed. Practical test results show that it is very effective and has good reliability and disturbance resistance.


The organ or tissue specific averaged SAR (SARosa) provides information about the localization of the absorption of electromagnetic fields. The SARosa is thus an important quantity for epidemiological research and radio frequency (RF) safety studies. It has already been assessed during mobile phone usage [1, 2] and near base station antennas [3]. In reality multiple sources are present in a varying environment. These realistic environments should normally be studied using a large number of time-consuming finite-difference time-domain (FDTD) simulations. A fast method to determine SARosa in realistic far-field environments based on a small number of FDTD simulations has been demonstrated at 950 MHz [4] for the virtual family boy (vfb) [5]. This method is now expanded to higher frequencies in order to study the frequency dependence of SARosa and cumulative exposure.


With the approval of the Decree-Law 75/2008, the applicants to the post of director of Portuguese public undergraduate schools have, mandatorily, to present an intervention project for the schools they intend to apply. This intervention project, which should take into account the school's educational project, needs to clarify the main lines of acting of the director during the four year period of his/her mandate. Two years after the publication of this Decree-Law, we applied a questionnaire to 48 Portuguese public school directors having as main objective to know some aspects of this document, namely to check its' importance as a instrument for the action of the director in the management and administration of the school. In this paper we shall present some of the results that we have obtained from the analysis of the questionnaires.


The physiological and biochemical changes of salt-tolerant line and salt-sensitive line of maize under the different concentrations of salt stress were determined.The results indicated that there were more chlorophyll content,less praline and MDA contents,and lower relative conductivity of organization of external seepage of salt-tolerant line with a small change,compared with salt-sensitive line.With the increase of salt concentration,the activities of SOD and POD of maize increased firstly,and then decreased,and peak value of salt-tolerant line appeared later.The CAT activity of salt-tolerant line was higher than that of salt-sensitive line.The Na/K value in seedling of salt-tolerant line was lower than that of salt-sensitive line,and the increasing range was small.And the Na/K value of underground part was opposite.


Organised for a world economy, rich in natural resources, and with a traditionally liberal and moral outlook, nineteenth century Britain was singularly well qualified to be the birthplace of the synthetic-dye industry. Yet, in the case of the organic chemical industry, the social and economic conditions that were often so favourable to the innovation and growth of industrial and commercial enterprises were not those best suited to combat the paternalism and planned economies of the aspiring new Germany. Thinking in terms of large-scale production of relatively cheap materials, British industrialists built up highly profitable industries based on the production and export of coal-tar and its distillation products. Without imagination, intellectual foresight, and stimulus from other industries, the British chemical industry stood aside whilst other nations developed their own dye-making enterprises. A European war and a renewal of belief in a modicum of State intervention were turning points marking a new determination on the part of Great Britain to be no longer subservient to foreign domination in the field of organic chemicals.


In traditional education, the science curriculum did not encourage teachers to teach information in meaningful contexts. Instead, they were encouraged to teach in isolation, without relating new information to real-life situations (Linn et al., 2000). More recently, the value in linking information with real-life situations has become apparent and teachers are continually looking for ways to practise this in their classroom. The Warriparinga Wetlands simulation has been designed to assist teachers in this area by demonstrating a real-life example of water conservation, through the use of multimedia and animations.


In the 1999 season of excavation at Tel Qedesh, in northern Israel, a small, perfectly intact stamped bulla dating to the Persian period was found. The bulla originally sealed a papyrus document. Thanks to its excellent preservation, it is possible to identify a series of key aspects of the object: the motif and type of seal used to stamp it, the way the bulla was created, and even the way in which the original document was folded and tied. These details allow us to identify the probable origin and date of the seal and contextualize its associated bulla within the site of Qedesh. This evidence, in conjunction with information from the late 5th century b.c.e. Murašû archive in Nippur, allows us to suggest that the seal's user may have been a person with Tyrian ties—perhaps a member of the Tyrian diaspora—who acquired his seal in Nippur and traveled to Qedesh where he used it to seal a document.


Abargaining problem with two players Labor (player L) and Management (player M) is considered. The players must decide the monthly wage payed to $\mathrm{L}$ by M. At the begining players $\mathrm{L}$ and $\mathrm{M}$ submit their offers $s_{1}$ and $s_{2}$ . If $s_{1}\leq s_{2}$ there is an agreement at $(s_{1}+s_{2})/2$ . If not, the arbitrator is called in and he chooses the offer which is nearest for his solution $\alpha$ . We suppose that asolution


Current study was conducted to identify the anastomosis groups and pathogenicity of binucleate Rhizoctonia species from soil samples in wheat production areas of Konya, Ankara, Yozgat, Eskisehir, Kirikkale, Kayseri, Kirsehir, Nevsehir and Aksaray provinces in the Central Anatolia Regions during 2009-2012 growing season. One thousand and two hundred fifty six (1256) soil samples were collected from wheat fields and isolations were made from the soil that using colonization of bait tissue. Species and anastomosis groups identification was done according to the basis of hyphal and colony morphology, anastomosis reaction with known tester isolates. Pathogenicity test was conducted with agar-plate assay with all isolates. Fifty one isolates were identified as binucleate Rhizoctonia and those isolates were found to be belonged to AG A, AG C, AG D (R. cerealis), AG E, AG G, AG H, AG I and AG K. In consequence of the pathogenicity tests performed, the groups other than AG D were not found to be pathogenic on susceptible wheat cultivar. AG C identified in this study is first record for Turkey, and also AG A, AG E, AG G and AG H groups were determined to be first in the wheat field soils in Turkey


Acoustic holography is a powerful tool for the localization and ranking of sound sources. However when dealing with non-anechoic spaces, classical methods have to be modified to take into account reflections on the walls of the testing room and, if necessary, the field radiated by secondary sources. In this paper, the field separation method is used to overcome these problems. The method used here consists in measuring the acoustic pressure on a double layer half-sphere array which base is lying on the surface of interest. Then, by using spherical harmonic expansions, contributions from outgoing and incoming waves can be separated if the impedance of the tested surface is high enough. Simulations on simple configurations and measurements on a car trunk mock-up are first presented. For the measured cases, the double layer array used is made-up of 2*36 carefully calibrated microphones. Comparison with results obtained with double layer SONAH are also shown. Finally, results obtained with a real car on a roller bench are reported.


A method and a system for providing additional information of E-mail according to information field indication are provided to immediately display additional information related to information included in contents of E-mail on a screen according to indication of a corresponding information field through an input unit so as to efficiently provide the additional information. A method of providing additional information of E-mail according to information field indication includes a step analyzing an information pattern with respect to at least one character string among contents of basic information of E-mail provided to a user terminal, and a step of providing the basic information and additional information according to the analyzed information pattern to the user terminal.


PURPOSE
Malignant mediastinal lymph nodes with unknown primary tumor is a rare occurrence. The purpose of this study is to specify some characteristics of the patients presenting with this disease and to define an adequate therapeutic approach.

MATERIAL AND METHODS
Between 1985 and 1997, we have operated on 54 patients with isolated non-small cell malignancy to mediastinal lymph nodes. Forty-nine patients underwent surgical biopsy of the mediastinal mass, generally followed by radiation therapy and/or chemotherapy. A mediastinal lymph node resection was performed in 5 patients.

RESULTS
Five patients were lost to follow-up (9.3%). The 5-year survival rate and the median survival were 12.4 +/- 5% and 7 months respectively. Four of the 7 patients who were still alive after follow-ups ranging from 10 to 68 months had undergone a lymph node resection. During the follow-up, a primary tumor was discovered in only 5 patients (11.4%).

CONCLUSIONS
Patients with isolated malignant lymph nodes of the mediastinum have a poor prognosis. In order to improve their survival, we recommend a more aggressive therapeutic approach comprising a chemotherapy and a mediastinal lymph node resection, associated in some cases with a lung resection. Radiation therapy of the mediastinum can be administered, principally in case of incomplete resection.


The present work provides an updated checklist of helminth species infecting invasive murid rodents ( Mus musculus , Rattus norvegicus , R. rattus , and Rattus sp.) in Mexico, including 35 helminth taxa (3 trematodes, 7 cestodes, 2 acanthocephalans, and 23 nematodes).  The helminthological records were compiled from 18 studies conducted in seven Mexican states up to May 2020.  Information on habitats, life stages, geographical locations, hosts, helminthological collections, prevalences, and bibliographic references are included, when available.  Finally, a new locality record of the nematode Hassalstrongylus musculi in Yucatan is provided.


Guanidine supported onto magnetic Fe3O4 nanoparticles was prepared and evaluated as a recoverable interphase nanocatalyst for the cyanosilylation of carbonyl compounds in good to high yields using trimethylsilylcyanide (TMSCN) in CH2Cl2 at room temperature. This simple experimental and product isolation procedure combined with easy recovery and high reusability (up to 20) of the catalyst are expected to contribute to the development of clean strategy for the preparation of silylated cyanohydrins.


Gravity effects are more prominent in thermal recovery simulations due to larger densitydifference between phases. Historically, the streamline method has been unable toaccount for gravity effects. This is a result of assuming that the fluid path follows thestreamline path and therefore no communication among streamlines. However with gravity,a fluid pathline is different from a fluid streamline. Each phase can move vertically asa result of the gravity segregation effect in addition to the flow along streamline.Gravity effects are accounted in the streamline method by an operator splitting technique.The idea is to isolate the convective flow from diffusion due to gravity for separatesolutions. The convective part is calculated along the common streamline trajectories andthe diffusion part is determined by the direction of gravity. While this has been done successfullyfor isothermal problems, it is still a challenge to obtain both accuracy and efficiencyfor non-isothermal flow. This paper further examines the mixed streamline methodwith an operator splitting technique for this class of problems. The pressure equation fordefining streamlines was derived by summing up the mass conservation equations. Then,the mass and heat transport equations in terms of the streamline time-of-flight coordinatewere solved for each streamline. A gravity step will be followed by solving the segregationequations over the dimensional grid. For simplification of modeling, heat was assumed totransfer by convection only, of which direction is parallel with the flowing phases and theinfluence of temperature in the simulation model is through changes in fluid viscosity only.The proposed approach was tested through simulation of heavy oil recovery by means ofhot waterflooding. The results were verified with those of a commercial fully implicit thermalsimulator.


SIR—Type 2 diabetes has long been associated with cognitive decline [1–6] and both Alzheimer's and vascular dementia [7–14]. Diagnosis and glycaemic control can be assessed by measuring glycosylated haemoglobin—or haemoglobin A1c (HbA1c)—level, which is a reflection of average blood glucose levels in the past 3 months. Previous studies have found high levels of HbA1c associated with worse memory, although most of these considered samples of young elderly (with mean age under 75 years) or included only diabetics [15, 16]. To date, very few studies have investigated the relationship between HbA1c level and cognition in populations of the very old (75+ years of age). One recent study found the interesting result that higher HbA1c level is associated with a decelerated decline in memory in patients over 85 years of age [17], suggesting that the harmful effect of elevated HbA1c levels on cognitive function may be less severe with increasing age. In this study, we studied the association between HbA1c and cognitive function in a sample of cognitively normal men greater than 75 years of age to examine whether this association varies by age.


This work imparts a control strategy for stand-alone photovoltaic (PV) system by means of fuzzy logic controller (FLC). The objective for this endeavor is to manage the power quality supplied from a PV system mainly in the course of load variation. The controller scheme is consist from voltage-frequency (Vf) control strategy based on a synchronous reference frame and the FLC. The FLC is an intelligent controller that is utilized to develop the power control parameters. To control the voltage, as well as the frequency of the three-phase voltage source inverter (VSI), seven gbell membership functions are implemented for the inputs as well as for the output. The results show that the controller was successful in delivering peak voltage of 339V. Furthermore, total harmonic distortion of the voltage waveform fulfilled the international standard, found to be 3.58%. The outcomes also indicated that the suggested controller have a superior response to fulfill the power quality requirements and show the robustness of the suggested control strategy.


Brain shift makes the pre-operative MRI navigation highly inaccurate hence the intraoperative modalities are adopted in surgical theatre. Due to the excellent economic and portability merits, the Ultrasound imaging is used at our collaborating hospital, Charing Cross Hospital, Imperial College London, UK. However, it is found that intraoperative diagnosis on Ultrasound images is not straightforward and consistent, even for very experienced clinical experts. Hence, there is a demand to design a Computer-aided-diagnosis system to provide a robust second opinion to help the surgeons. The proposed CAD system based on "Mixed-Attention Res-U-net with asymmetric loss function" achieves the state-of-the-art results comparing to the ground truth by classification at pixel-level directly, it also outperforms all the current main stream pixel-level classification methods (e.g. U-net, FCN) in all the evaluation metrices.


In situ TEM gas-cell imaging and spectroscopy with in situ XRD have been applied to reveal morphological changes in NiFe2O4@Co3O4 core–shell nanoparticles in hydrogen. The core–shell structure is retained upon reduction under mild conditions (180 °C for 1 h), resulting in a partially reduced shell. The core–shell structure was retained after exposing these reduced NiFe2O4@Co3O4 core–shell nanoparticles to Fischer–Tropsch conditions at 230 °C and 20 bar. Slightly harsher reduction (230 °C, 2 h) resulted in restructuring of the NiFe2O4@Co3O4 core–shell nanoparticles to form cobalt islands in addition to partially reduced NiFe2O4. NiFe2O4 underwent further transformation upon exposure to Fischer–Tropsch conditions, resulting in the formation of iron carbide and nickel/iron–nickel alloy. The turnover frequency in the Fischer–Tropsch synthesis over NiFe2O4@Co3O4 core–shell nanoparticles reduced in hydrogen at 180 °C for 1 h was estimated to be less than 0.02 s–1 (cobalt-time yield of 8.40 μmol.g-1.s–1) with a C5+ selectivity of 38 C-%. The low turnover frequency under these conditions in relation to the turnover frequency obtained with unsupported cobalt is attributed to the strain in the catalytically active cobalt.


The external effects is an important research area in economic theory of microeconomics.In this paper,the external effects of environmental resources of the important origin of Yellow River in Gannan Maqu were analyzed by the theory.And it is pointed out that the "public goods" properties of the environmental resources led to the excessive use of local environmental resources.The existing"free-rider phenomenon also led to the insufficient supply of the ecological environment development.Through the research on the production and performance of the external effect,this paper also studied the measures and system choices of the internalization.


Simple Summary There is a wide range of historical, archaeological and biological sources to help understand the nature of health and disease in the ancient Roman world. In this study, we examine various predisposing elements typical of the urban environment in relation to zoonotic diseases in the ancient Roman cities of Pompeii and Herculaneum, both devastated by pyroclastic surges as a consequence of the eruption of Mount Somma–Vesuvius in 79 CE. We analyse the meaning and value of the sources to develop an understanding of the many features of everyday life in these cities. We make judgements about issues relevant to the reconstruction of the past, and finally, we synthesize evidence from different sources to construct historical explanations and arguments in relation to the transmission of zoonotic diseases in these ancient Roman populations. Abstract There is no doubt that the cultural and urban environments contributed to the animal–human interaction in the daily life of the ancient Roman world. The singularity of the circumstances of the burial of Pompeii and Herculaneum, together with literary sources and the extraordinary state of preservation of the archaeological and biological material found, has provided researchers with an opportunity, unique in its kind, to reconstruct the life and ways of living of its inhabitants. This study illustrates the main drivers and mechanisms for the distribution and transmission of zoonotic diseases in these ancient Roman populations, such as (i) the large number and role that different animal species played in the ancient Roman world; (ii) the environmental conditions for the survival of parasites, pathogens and vectors; (iii) the great variety and intensity of commercial activities and occupations that presented certain risks of infections; (iv) the absence of adequate safety controls during processing, distribution and preservation of foodstuffs in unsuitable environments and some culinary habits; (v) the inadequate mechanisms of the disposal of human waste and the biotic contamination of watercourses and reservoirs; and finally (vi) the use of animals related to religious and cultural practices.


This study aims to analyze the effect of ability, learning motivation and school environment on student achievement at State Junior High School 17 Banjarmasin. The research method used is analytic survey. The type of research is explanatory research. A sample of 75 students. Data collection techniques using questionnaires, documentation, interviews and observations. Validity and reliability tests were carried out on the research instrument. Data were analyzed by multiple linear regression analysis. The results showed that the ability of teachers, students' learning motivation and the school environment partially and simultaneously had a significant effect on student achievement at State Junior High School 17 Banjarmasin. The contribution of the independent variable's influence on the ability of teachers, students' learning motivation and school environment on learning achievement is 64.50%. Of the three independent variables, the school environment has a dominant influence on student achievement.


Background: Metabolic syndrome (MetS) is associated with increased risk for diabetes and coronary heart disease. Data suggest that MetS starts even in children. Thus, it is important to understand the role of MetS and the risks related to it. Furthermore, white blood cell count (WBCC) is available in routine examination and it has been proved to be related to risks of MetS.


Diabetes mellitus and peripheral arterial disease frequently occur particularly at older age. Their simultaneous course presents a significant risk of vascular complications. The authors deal with a mutual relationship of the two diseases, the incidence of complications and ongoing pathophysiological changes as well as diagnos tic possibilities. The treatment places emphasis primarily on influencing the risk factors of both diseases – ban on smoking, normalization of blood pressure, the lipid spectrum values, a rigorous control of blood glucose. The specific treatment for the peripheral arterial disease is always based on movement therapy, as to medication antiplatelet drugs are indicated for symptomatic patients, as to vasoactive drugs prostanoids or possibly cilostazol or naftidrofuryl are administered to a selected group of patients. Revascularization is justified in patients with life-limiting claudications with an insufficient response to conservative treatment. Kľúčové slová diabetes mellitus diagnostika PAO liečba PAO patogenéza PAO periférne artériové ochorenie (PAO)


The segmentation of brain tissue finds an important role in many clinical applications. In this paper we propose a new skull stripping method for Magnetic Resonance Images of human head scan. We use clustering based technique to find the brain boundary inside the skull. First we find the clusters based on the intensity. Then the centroids of these clusters are found. These centroids are then connected, which form the brain boundary. We use 2D region growing method to connect all the clusters. By the same region growing method we remove the skull area and the clusters which are outside of the skull region. Finally we refine the edge of the brain by connecting the values of maximum intensity values.


Kafka is generally considered as an expressionist writer of modernism. However,with the rise of postmodernism theory,people have found in his works some typical elements of postmodernism. Such postmodern characteristics as uncertainty,internality,deconstruction,entertainment,intertextuality,fragments and absurdity are embodied in the creation of Kafka's short stories.


This paper presents a degradation model considering a permanent impact of the environment on the system. A two-stage environment is considered; shocks impacting the degradation rates can occur in the stressed mode. We develop methods to estimate/detect the occurrence of shocks and assess the remaining useful lifetime. The studied examples showed a good performance of the estimation/detection methods.


Spin engineering is an effective strategy to improve the performance of catalysts, but it has been rarely demonstrated for the acetonitrile reduction reaction (ARR) to date.


Water is an important food and an important natural resource. In order to protect these are the Environmental Code and the EU directive given to water protection and related water protection regula ...


We characterize the performance of standard and micro genetic algorithms when applied to focusing inside of an opaque media using feedback from a fluorescent guidestar particle. Using this feedback modality we find that the algorithms optimize more quickly (but to a lower enhancement) than when using reflective feedback, with the underlying mechanism being the fluorescence signal's multimodal nature and lower signal-to-noise ratio. We also find that both algorithms' performance decrease at very large numbers of bins due to decoherence effects related to a bin-dependent iteration time. To mitigate this effect we implement multithreaded functionality in the genetic algorithms and find that for our specific computer we obtain a 3.3 × improvement in speed utilizing multithreading. These results demonstrate the usefulness of both algorithms for focusing inside of opaque media, which has applications in biological imaging and the study of subsurface chemical reactions in heterogeneous materials.


Objective: Sporadic late-onset nemaline myopathy (SLONM) is a rare, late-onset myopathy that progresses subacutely. If associated with a monoclonal gammopathy of unknown significance (MGUS), the outcome is unfavorable: the majority of these patients die within 1 to 5 years of respiratory failure. This study aims to qualitatively assess the long-term treatment effect of high-dose melphalan (HDM) followed by autologous stem cell transplantation (SCT) in a series of 8 patients with SLONM-MGUS. Methods: We performed a retrospective case series study (n = 8) on the long-term (1–8 years) treatment effect of HDM followed by autologous SCT (HDM-SCT) on survival, muscle strength, and functional capacities. Results: Seven patients showed a lasting moderate–good clinical response, 2 of them after the second HDM-SCT. All of them had a complete, a very good partial, or a partial hematologic response. One patient showed no clinical or hematologic response and died. Conclusions: This case series shows the positive effect of HDM-SCT in this rare disorder. Factors that may portend an unfavorable outcome are a long disease course before the hematologic treatment and a poor hematologic response. Age at onset, level and type of M protein (κ vs λ), and severity of muscle weakness were not associated with a specific outcome. Classification of evidence: This study provides Class IV evidence that for patients with SLONM-MGUS, HDM-SCT increases the probability of survival and functional improvement.


Chapter 5 identifies the material factors that al-Qaeda and ISIS draw upon to attract attention to their proto-states by online users and traditional media outlets. It begins by recognizing the highly crowded, competitive nature of the online environment and the fact that both proto-states have had millions of news items written about them and millions of online views of their content. It then establishes a clear association between material conditions linked to the proto-states' defining elements and spikes in attention by online users and international news outlets. Using Google Trend Score and Nexis-Uni data, the chapter demonstrates how material elements related to the definitional components of ideology, aggression, governance, population control, territorial control, and alliances are all associated with the attention of online users and traditional media sources.


The development of machines that are able to sustain a conversation with a human being has long been a challenging goal. Only recently, however, substantial improvements in the technology of speech recognition and understanding have enabled the implementation of experimental spoken dialogue systems, acting within specific semantic domains. The renewed interest in this area is represented by the numerous papers which appeared in conferences such as ESCA Eurospeech, ICSLP, and ICASSP, as well as by events such as the 1993 International Symposium on Spoken Dialogue and the 1995 ESCA Workshop on Spoken Dialogue Systems.


The overview of scientific research works in which techniques and results of analytical and experimental studying of power and kinematic characteristics of operation of roller drill bits is stated in this paper. The interest to this subject is explained by its great practical importance. Economic indicators of a well construction depend on the overall performance of the drilling tool. At the same time, results of researches often have contradictory character that can be explained by the high complexity of processes happening during the bit operation on a borehole bottom. The analyzed works are grouped according to the fields of researches. The overview of main works devoted to studying of kinematics of roller drill bits, to interaction of elements of drilling bit cutting structure with the destroyed rock, to the calculation of efforts and analysis of tension of drilling bit bearing and cutting structure elements by means of various experimental methods and methods of mathematical modeling is provided. The provided analysis of known results of researches in this field is not comprehensive, but can be useful in case of further studying of this issue. The results of the investigational study of a load distribution between drilling bit bearings applying the model of the drilling bit bearing assembly made of photoelastic material are also considered in this paper. It is established that the nature of a load distribution between bearings depends on the radius of the effort application to a roller. In case of a little change of radius in a certain area, there is a considerable redistribution of loading between drilling bit bearings. The placement recommendations for the optimization of a drilling bit cutting structure on a roller surface are offered according to research results.


A special amine called ketimine was prepared from amino terminated polyether and methyl ethyl ketone via Micheal addition reaction.The one component polyurea was prepared from the ketimine mixed with the isocyanate prepolymers.The successful preparation of the ketimine and the urea groups in polyurea coatings was confirmed by FTIR spectra.The hard drying time of the one component polyurea was 24 hours,and the one component polyurea coating had exceptional physical properties such as elongation at break,flexibility,impact strength,chemical and water resistance and so on.


The authors of the scientific publication listed the main regulatory and legal documents of Ukraine, which provide for the preservation and strengthening of the health of Ukrainians; the topics of conversations (author Z. Dikhtyarenko) are listed. These topics are desirable to conduct during training, the educational process, and, especially, remotely, in order to preserve and strengthen the health of combat horting athletes (and, if possible, under conditions of martial law). And questions for pupils and student youth, cadets (author D. Borsukova), and also multiple choice questions for pupils and student youth, cadets (author A. Steshyts). Z. Dikhtyarenko and A. Steshyts agree that the development of the structure and components of the concept of "health" in scientific literature has acquired various modifications many times: physical, mental, spiritual (graphic representation is a pyramid); physical, social, spiritual (graphic representation is a pyramid); physical, social, intellectual, emotional, spiritual (graphic image is a flower); physical, emotional, mental, social, personal, spiritual (a graphic image is a flower); physical, somatic, mental (mental, emotional), social; biological, social, psychological, spiritual (physical, intellectual, moral); physical, mental, moral, spiritual, social, professional (graphic representation is a cyclic scheme) [4].


Speech act verb of swearing language serves as a basic category in Chinese language, whether it is ancient or modern language, euphemism, colloquialism, or mandarin. Diachronic method and quantitative statistical analysis are employed to investigate the diachronic evolution and synchronic distribution of the conceptual field of speech act verb "swearing language". In the pre-Qin period, "詈 (Li, abusive language)" prevailed with a few combinations on and out of the field. In the Middle Chinese period, "骂 (Ma, cursing)" gradually replaced "詈" to win the dominant position, and new combination forms with elements in and out of conceptual field emerged. In the Neoteric Chinese period, "骂" occupied a dominant position with "啳 (Quan)" and "诀 (Jue)" included, new combinations with elements in and out of conceptual field have been slashed. The conceptual field of speech act verb swearing language in modern Chinese language covers lots of members. "骂" is the most widely used, followed by "诀" and "啳", with other members scattered in southern dialects.


Study effect of maternal gestational weight gain (GWG) on the relationship between maternal menarcheal age (MMA) and child growth and overweight risk and examine socio‐demographics characteristics of excessive GWG.


The implant crown is placed and rotated until the external hex antirotational feature of the implant engages the internal hex antirotational feature of the crown. The prosthesis is then held in place as the screw is manually tightened at less than full torque. Subgingival probe evaluation of the interface is contraindicated because of the danger of scratching the implant with the explorer. A radiograph taken at the


The aim of this paper is to prove the existence of common coupled coincidence points and common coupled fixed points for a pair of compatible maps satisfying condition (B) with a rational expression in partially ordered metric spaces. Further, we discuss the importance of rational expression in condition (B). Our results extend and improve the results of Luong and Thuan [N.L. Luoung, N.X. Thuan, Coupled fixed point theorems in partially ordered metric spaces, Bull. Math. Anal. Appl. 2 (2010) 14–24], generalize the results of Lakshmikantham and Ciric [V. Lakshmikantham, Lj.B. Ciric, Coupled fixed point theorems for nonlinear contractions in partially ordered metric spaces, Nonlinear Anal. 70 (2009) 4341– 4349], and Saud and Abdullah [S.M. Alsulami, A. Alotaibi, Coupled cpoincidence The second author was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (Grant Number: 2011-0021821). 2 Corresponding author. Copyright c © 2015 by the Mathematical Association of Thailand. All rights reserved. 562 Thai J. Math. 13 (2015)/ G.V.R. Babu et al. point theorems for compatible mappings in partially ordered metric spaces, Bull. Math. Anal. Appl. 4 (2) (2012) 129–138].