Purpose. We presented the results of modeling the process of xylol spread in the cylinder for painting large dimension products. The paint is covered with the help of paint remote control. Methods. The set task is solved numerically in the program sphere FLUENT. Results. We received data about fields of air speed and contaminator concentration inside the camera with "active" and "passive" modules. We considered the variants with ventilation and without ventilation of "passive" modules. The task is solved in 3D setting for stationary and non-stationary regimes of evaporation. Dangerous concentrations of solvent fumes are localized near places where aerosol supplies paint and do not go out of the borders of "active" modules. Conclusions. Blowing of "passive" modules excludes appearance of circulation zones.


This study aims to look at the legality of human rights restrictions in a military emergency in Indonesia. This research uses a normative legal research type. The choice of this type of normative analysis is related to the formulation of problems that become legal research issues. The findings of this study are that restrictions on human rights in a state of military emergency are justified because the human rights possessed by every human being do not apply, primarily if an army emergency is enforced, all human rights possessed by every human being can be limited to the implementation for the respect of human rights, the enforcement of a military emergency must see the condition of a region whether it is categorized as threatening the life of the nation or not. For this reason, this study recommends that the Government, in imposing restrictions on human rights in a military emergency, must be based on the element of a dangerous threat.


Primary ovarian leiomyoma is a rare tumor, accounting for only 0.5%-1% of benign ovarian neoplasms. About 80 cases have been reported in the literature worldwide to date. Most cases are asymptomatic and usually found incidentally in routine gynecologic workup, during surgery, or at autopsy. Ovarian leiomyoma is diffi cult to be differentiated from other ovarian benign and malignant neoplasms, particularly from large ovarian solid tumors. It is important to consider ovary-preserving surgery as the fi rst treatment modality in patients of reproductive age after excluding the possibility of malignancy, given that 80% of ovarian leiomyomas occur in premenopausal women and the size of the mass is larger in younger patients. Here we report a case of ovarian leiomyoma in a 38-year-old female patient who underwent laparoscopic excision of left ovarian mass and uterine myomectomy.


In this paper, study report and solutions of the interconnection and interworking of voice, video and data transmission of traffic network nodes in Jilin Province by researches on network construction of transport sectors and the visiting and investigational study of relevant network equipment manufacturers and operators in Jilin province are carried out. On this basis, technical standards of Jilin traffic information backbone network construction, traffic communication information transmission including network data, voice and video, grading protection construction of traffic information network security, construction standards of traffic information network IT room, and test standards of traffic information network acceptance have been developed. The study aims to promote the construction of Jilin traffic information network and network security level, and improve the efficiency of its transportation network interconnection, network construction and operation and maintenance from the perspective of technical support, playing an exemplary role in traffic information backbone network interlinking of other provinces and regions.


The poly(2,5-dipentyloxy-para-phenylene ethynylene)(P) was synthesized by Pd-catalyzed Sonogashira coupling reaction.Due to causing energy transfer between the nitrobenzene's quenchers and the polymer chains through the charge-transfer interaction,the fluorescence quenched properties of P varied obviously with the para-substituting group's structure in the nitrobenzene derivatives.The fluorescence quenching efficiency of quenchers improved with increasing of electron repulsion capability of the para-substituting group.The fluorescence quenching efficiency increased nonlinearly with the concentration of the quenchers and had,however,no relation with the quenching time.


Abstract : "Mode interaction" instabilities of aircraft were investigated. "Mode interaction" refers to coupling between an elastic mode and a rigid body mode of the free system. Three rather general airframe configurations are analyzed in detail. It is shown that systems which tend toward steady state divergence are particularly susceptible to mode interaction. Also, that aerodynamic damping terms can have a destabilizing effect upon a free system. The analyses show that aeroelastic systems which possess no finite frequency elastic mode can be susceptible to a finite frequency in stability. Computer studies of several different airframe configurations are discussed. An appen dix contains stability charts for an aircraft having two rigid body modes and one elastic mode.


Given a suitable regular ring R, we construct a sheaf-like representation for R as a ring of continuous sections from a completely regular space to an appropriately toplogized disjoint union of factor rings corresponding to ''extremal" pseudo-rank functions. Applied to rings which are complete with respect to a rank function this representation is an isomorphism, the completely regular space is extremally disconnected and compact, and the * 'stalks" are the simple factor rings.


This study comprises an attempt to validate two
simulation-games designed to teach concepts concerned
with the theory of organic evolution to children in the
nine to eleven age range. The author discusses the
nature of simulation-games and their value in the learning
situation, and describes the attempts of other writers to
evaluate simulation-games at both cognitive and affective
levels. He outlines the development of two games, and
describes their evaluation using an illuminative approach
consisting of four different assessment procedures. [Continues.]


Summary.  This article reviews the epidemiology of inhibitor formation in patients receiving recombinant factor VIII (rFVIII) replacement therapy for haemophilia A. Data from pivotal trial programmes, post‐marketing surveillance studies, and pharmacovigilance studies for all available rFVIII products were reviewed. To date, no comparative studies have been performed, and in the non‐comparative studies, there were differences in the patient population enrolled and study design (including the number of patient exposure days). In the absence of comparative clinical trials, it is not possible to make comparisons between inhibitor data for the various rFVIII products. This review of the epidemiological data shows that across the pivotal trial programmes for rFVIII products, the observed incidence of inhibitors was in the range of 15–32% in previously untreated patients (PUPs) and 0.9–2.9% in previously treated patients (PTPs). High‐titre inhibitors (peak >5 BU) were detected in 10–16% of PUPs and 0–2.3% of PTPs. Several initiatives proposed to help standardize collection and interpretation of inhibitor data for patients receiving rFVIII treatment are described. Such standardization would help to clarify the epidemiology of inhibitor formation across FVIII treatments.


Abstract. Body size is an important trait with implications for energy use and ecology as well as generation time and evolutionary rates. Turritelline gastropods are widely distributed through geologic time and space, making them an excellent group for evaluating macroevolutionary patterns. To evaluate the pattern of body-size change in turritelline gastropods, we compiled a dataset of shell lengths of 316 species of turritelline gastropods spanning the Jurassic to Recent. Type specimens were almost always significantly larger than specimen distributions from the same species. We found that turritelline gastropod size was inversely correlated with latitude, a trend likely driven by the Neogene–Recent diversification of small-bodied Southern Hemisphere taxa. A time series model was applied to distinguish among three possible macroevolutionary patterns: unbiased random walk (no directional trend), biased random walk (directional trend), and stasis (no net change). We determined that turritelline gastropods have experienced stasis in body size throughout their evolutionary history, adding to the growing literature documenting directionless body-size trends in marine invertebrate clades. Stasis of geographically widespread clades may be the result of ecological variability across the environmental range occupied by the group or differential diversification into opposing environments. Turritelline life-history patterns, especially their reproductive strategy that combines a short life span and decline in growth rate around 1 year of age to reallocate energy to reproduction, might circumvent selection for longevity and larger size, while further decrease in minimum size is likely limited by feeding efficiency and anti-predatory defense. The expectation that species or clades should continue to evolve to occupy larger size classes conflicts with the evolutionary advantages of small size, which in turritelline gastropods include high generational turnover and larger population sizes that yield opportunities for genetic variance.


A 29-year-old Korean man presented with a 3-year history of lesions. On physical examination, erythematous to brownish xerotic patches were seen on the face and neck (Fig. 1a), with xerosis over the whole body. He was otherwise well, with no relevant medical or family history. Laboratory investigations, including complete blood cell count, blood chemistry studies, serum electrolyte levels, urine analysis, chest radiography and electrocardiography were within normal limits; however, his IgE level was 210 kU ⁄ L (normal range 0–100 kU ⁄ L). Skin prick testing gave positive results for Dermatophagoides pteronyssinus and Dermatophagoides farinae. Based on the laboratory findings, clinical appearance and chronic course of the disease, a diagnosis of head and neck atopic dermatitis (HND) was made. The patient was treated with systemic antihistamines, moisturizers, mild-potency topical corticosteroids (hydrocortisone 2.5%) and a topical calcineurin inhibitor (tacrolimus 0.03%), but there was no improvement during a 4-year follow-up period. Four years after the first visit, an erythematous indurated plaque was noticed on the right neck, which failed to resolve despite treatment with topical steroid (methylprednisolone aceponate 0.1%) (Fig. 1b). In addition, inguinal and axillary lymphadenopathy was detected.


This study focused on teacher act in classroom interaction based on Sinclair and Coulthard Model. The aims of this study are (a) to find out the types of act in classroom interaction that the teacher used based on Sinclair and Coulthard Model, (b) to describe how the types of acts are realized in classroom interaction that the teacher used based on Sinclair and Coulthard Model. This research used qualitative research. To answer the problems of the study, the data were collected in two ways by observing, and recording. The data were analyzed based on Sinclair and Coulthard model. The results of this research were the following: (a) there were 16 types of acts in teacher utterances, namely:  Marker, Starter, Clue, Reply, Accept, Elicitation, Evaluate, Informative, Directive, React, Check, Conclusion, Comment, Cue, Bid, and Nomination. Meanwhile Prompt, Acknowledge, Metastatement, Loop, Silent stress, and Aside were not found during the teaching and learning process. (b) The realization of types of act Marker of act was realized by a closed class of item "Ok''. Starter of act was realized by a command. Clue of act was realized by a statement. Reply act was realized by question. Accept of act was realized by a close of item "good'. Elicitation of act was realized by question. Evaluate of act was realized by statement and question tag. Informative of act was realized by a statement. Directive of act was realized by a command. React of act was realized by a non linguistic. Check of act was realized by statement. Conclusion of act was realized by a statement "so". Comment of act was realized by a statement. Nomination of act was realized by a closed class consisting of the names of the pupil "please you". Cue of act was realized by a close class of which "raise your hand". Bid of act was realized by a close class of verbal items "Miss".Keywords: Teacher Act, Classroom interaction, Act Sinclair and Coulthard.


thinking (Table 4.12) showed that at baseline the numbers of non-rugby and previous players showing deficits were less than for rugby players. Although for the former two groups the numbers of participants showing deficits decreased by the third year more so for non rugby as opposed to the previous rugby group, the percentage of players showing deficits increased markedly for the rugby playing group. In addition, the percentage of participants in the more than 1 standard deviation above the mean group was higher for the non rugby group as opposed to the other two groups. Other than providing an explanation for the time effect for SIM when the effect of VOC has been accounted for, these findings could suggest that possibly the non rugby group with minimal insults to the brain, compared with the rugby group, were not hampered in terms of development of abstract thinking and that possibly they were less vulnerable given the protective factors associated with their higher estimated BRC. The findings of more deficits for SIM amongst participants playing rugby and sustaining insults to the brain could also be explained by the statistically significant lower VOC scores and the statistically significant concussion scores suggesting greater vulnerability for these participants in terms of the development of specific cognitive functions. The previous players' performances after three years were not dissimilar from the non-players suggesting that one could again argue for the existence of a protective factor


Tetrakis(bicyclo[2.2.2]oct-2-ene)-fused calix[4]pyrrole, 5, was obtained starting from (E)-1,2-bis(phenylsulfonyl)ethylene. This new calixpyrrole derivative is the prospective precursor of tetrabenzocalix[4]pyrrole, a potential ion-pair receptor and an attractive species as a possible deep-walled 'molecular container'.


A harmonic suppression band-pass filter based on symmetrical microstrip electromagnetic bandgap (EBG) structure is designed, fabricated and measured. Basic agreement between the experimental and simulation results has been achieved.


This is the final, published PDF of an article published by the Canadian Journal of Career development in 2011 and reproduces with permission from the publisher. The full issue is available online at: http://cjcdonline.ca/download/vol-18-issue-1/


Measurements of plasma volume in a group of patients with early acute rheumatic fever are reported. The results of this study indicate that the decrease in hematocrit values observed during this phase of the disease is most often related to dilution of the erythrocyte mass by an increased plasma volume.


The epigallocatechin gallate(EGCG) concentrations in plasma and liver tissues were determined by the reversed-phase high performance liquid chromatography(RP-HPLC) after a single intraperitoneal injection at 150mg/kg for Darkbarbel catfish,Pelteobagrus vachelli.The results showed that EGCG was absorbed and eliminated very quickly in high temperature(20℃).However,EGCG was absorbed and eliminated very slowly in low temperature(10℃).The T1/2Ka,T1/2α and T1/2β were 0.21h,2.07h and 22.89h at 20℃,respectively.And the corresponding values were 5.67h,9.53h and 207.49h at 10℃,respectively.The AUC,Tp and C max were 5195.41μg·h/ml,0.95h and 257.75μg/ml at 20℃.Then all the values were 17283.03μg·h/ml,12.56h and 117.16μg/ml at 10℃,respectively.The elimination half-life of EGCG in liver was 24.15h at 20℃,while the value was 64.17h at 10℃.Therefore,these results indicate that EGCG absorption,distribution and excretion at 20℃ were more quickly than at 10℃.And the differences of metabolic kinetics and liver elimination of EGCG were significant at 20℃ and at 10℃.


Our purpose in this paper is to investigate commutativity of a ring with involution [Formula: see text] which admits a generalized derivation satisfying certain algebraic identities. Some well-known results characterizing commutativity of prime rings have been generalized. Moreover, we provide examples to show that the assumed restrictions cannot be relaxed.


The ballistic protection device (1) according to the invention comprises a grate (2) mesh which is characterized in that at least one side of this mesh roughness (200, 201). These protrusions (200, 201) allow to decrease the distance between the cap of the projectile and the contour of the mesh without decreasing the size of the meshes and thus without substantially increasing the weight of the device.


Uncertainty management of the large scale wind power resources is mainly known as one of the most challenging aspects in future electricity market operations, where network operation may put at risk due to the wind power forecasting errors. Therefore, it is necessary to evaluate the impact of the wind power uncertainty on the operator risk-taking by using validated tools. This paper proposes a new mixed integer linear programming model for joint energy and reserve market clearing taking into account the co-optimization of the market clearing and operation cost of the thermal units. Also, wind power uncertainty is handled by means of two-stage stochastic programming and risk concept is introduced and formulated via a well-known measure to account for operator risk taking level. The proposed model is formulated as a two-stage stochastic programming where it clears the joint energy and reserve markets considering different penetration and forecasting accuracy levels of the wind power. Furthermore, supplement...


Work-related injuries involving significant physical loads are of growing concern, as these injuries can negatively impact work productivity, physical health and well-being at work, but also have economic costs due to absenteeism. This observational study aims to quantify the ergonomical assessment of dockworkers using wearable devices to reduce the risk of injuries. Two different gestures are analyzed and observed using a wearable mocap system: Task1A securing the lash bars and Task 1B as lifting and locking process. Additional tests and questionnaire were also requested: FMS, HHD, RAND-36, ODI, and TSK questionnaires. As result, it was found a large spread between the maximum and minimum degrees and the range in which they are working among the different dockworkers. Despite the large heterogeneity, we found for task 1B that the wrist was held in extreme positions, and a significant correlation was found between the time and standard deviation of the low back (R = 0.45, p = 0.045). In addition, all participants reported having complaints; 66% had kinesiophobia, 60% were overweight, and the mean score on the FMS was 15. The occurrence of fatigue, complaints, kinesiophobia, a challenging work environment, or an unhealthy lifestyle may lead to altered movement patterns, which could possibly increase the risk of injury. Based on the results, we recommend implementing a warm-up and an individualized prevention program to reduce the risk of injury.


Summary The character of persisting corpora lutea in hypophysectomized rats was not influenced by the injection of oestrin, progestin or the follicle stimulating hormone of the hypophysis. The luteinizing fraction, however, caused almost total regression of the corpora lutea with marked diminution of ovarian weight.


Summary 1. 1 M NaCl-soluble and 0.5 M acetic acid-soluble collagen were purified from pig uterus. The total yield was approximately 0.03% of the weight of the wet tissue. 2. After heat denaturation, the α- and β- components were separated on Sephadex G-200 and CM-cellulose column. Like the finding in human uterine collagen, less α- and more β- components were found in the salt soluble collagen of pig uterus than in the skin of the rat and human being. However, more α- and less β-component were found in the uterine collagen of pig than in that from the human being. 3. Pig uterine collagen contained a somewhat higher level of hydroxyproline and hydroxylysine than dermal collagen of rat and human being.


Current realities of tighter process tolerances combined with continued reduction in engineering resources per metrology tool require that every step of controlling a process a be made more efficient. Analyzing the quality of metrolgoy results, from equipment such as CD SEMs, can involve many factors that include image quality, measurement outputs, focus setting, and amplitude of system settings that play a role in the metrology results. The most efficient means of accessing large volumes of data today is via the World Wide Web. This paper provides examples of metrology problem resolutions that were achieved through the use of WWW on-line analysis of CD SEM results. The relational database that contains the measurement results, CD SEM settings, and metrology and pattern recognition images can be accessed from any fab PC, and can also be accessed from any fab PC, and can also be accessed from outside the fab by personnel with proper levels of security. Simple navigation through a web browser and the completeness of the data in the results database greatly improve the efficiency of the metrologist and the quality of the diagnosis, for improved process control and personal productivity.


We have demonstrated fluorescence resonance energy transfer (FRET) between lanthanide-ion doped oxide nanoparticles acting as donors and organic acceptor molecules (Cy5). Due to the long nanoparticle lifetime and the large Stokes shift between nanoparticle absorption and emission, unambiguous and precise FRET measurements can be performed despite the presence of large free acceptor oncentrations. We determined FRET efficiencies as a function of Cy5 concentration which are in very good agreement with a multiple acceptor-multiple donor calculation.


This paper presents the implementation of a compiler of SBVR Structured English to SQL data models and queries, with SBVR Logical Formulation as an intermediate step. The compiler is implemented in OMeta/JS and targets browsers that support Web SQL Databases. We discuss each stage of our compiler as well as the optimizations and necessary tradeoffs.


BACKGROUND: Due to the multifaceted pathology of neurovascular damage in stroke, providing combined therapies aimed at underline different mechanisms may be a promising strategy. We have demonstrated that echogenic liposomes (ELIP) can effectively deliver xenon (Xe), a N -methyl-D-aspartate receptor antagonist, into brain tissue for dose-dependent neuroprotection. This study evaluates the synergic therapeutic effects of ELIP delivering Xe with an anti-inflammatory gas, hydrogen sulfide (H 2 S), or a free radical scavenger, hydrogen (H 2 ), in a rat stroke model. METHODS: A gas mixture of 1% H 2 S with 99% Xe or 30% H 2 with 70% Xe was loaded into ELIP by a pressurization-freeze method. Rats (n=25) undergoing 2-hour middle cerebral artery occlusion were then treated with low-dose Xe-ELIP, H 2 S/Xe-ELIP, or H 2 /Xe-ELIP, respectively, at 3 hours after stroke onset. One MHz low-amplitude (0.18 MPa) ultrasound was directed over the internal carotid artery to trigger gas release. Behavioral tests were conducted for three days following surgery. After sacrifice, brain sections were evaluated for infarction and apoptotic neuronal death using triphenyltetrazolium chloride (TTC) and TUNEL staining. Infarct size was evaluated as normalized infarct volume (%). RESULTS: Strokes without treatment had an infarct size of 27± 6%. Strokes with Xe-ELIP treatment exhibited an infarct size of 20±4% (p=0.232 vs. no treatment). Strokes with H 2 S/Xe-ELIP and H 2 /Xe-ELIP treatments demonstrated a further infarct size reduction to 7.1±1.6% (p=0.017 vs. no treatment) and 8.8±1.9% (p=0.032 vs. no treatment), respectively. Neurologic behavior tests reflected infarct size. CONCLUSIONS: In this study, using echogenic immunoliposomes as a vehicle, co-delivery of therapeutics targeting different mechanisms of neurovascular damage results in a synergic therapeutic effect. This methodology provides an avenue for evaluation of other synergic agents for use in acute stroke.


In this paper, we investigate the distribution strategy of a software publisher. The user adoption context is characterized by uncertainty about quality (experience good) and heterogeneous piracy costs. Users can purchase or get unauthorized/illegal copies (digital piracy) of the software during two periods (or not adopt at all). Between these two periods, users can acquire information through word-of-mouth. To maximize profit, the publisher needs to decide about price, quality and level of monitoring of piracy. We show that the software publisher can profit from accommodation a certain level of piracy of the product. We add to the literature by explicitly considering the opportunity for the publisher to cheat about future price and monitoring levels (misleading announcements). This strategy that is falsely permissive towards piracy, can sometimes appear more profitable. However, when the degree of sophistication of user expectations about the publisher's strategy increases, only a strategy that is permissive (with respect to piracy) with non misleading announcements remains robust.


The issues and development trends of the case-technology use for the productive student self-work intensification in the framework of the third generation FSES are researched. The key factors necessary for the case formation in the discipline "Mathematics" in the technical institution of higher education are formed. The methodology for the individual educational case formation in the context of productive learning activity provision are proposed and tested.


Stress failure of alveolar epithelial cells is a common feature of ventilator‐injured lungs. While some injured cells undergo necrosis, others repair their plasma membrane (PM) wounds through non‐secretory exocytosis of intracellular vesicles (e.g. lysosomes) to and cytoskeleton remodeling at and around the wound. We measured the timing of lysosomal trafficking and F‐actin reorganization following micropuncture injury in primary type I alveolar epithelial cells (ATI).


The implementation design of digital up conversion module in MIMO-OFDM high speed digital radio is described in this paper.In allusion to the parameter about modulation and encoding given from the radio's total design,the whole design and the subsystem is presented with VHDL hardware description language and implemented with a Altera's FPGA.


We use cyclic charge-discharge experiments to evaluate the capacity retention rates of two quinone-bromide flow batteries (QBFBs). These aqueous QBFBs use a negative electrolyte containing either anthraquinone-2,7-disulfonic acid (AQDS) or anthraquinone-2-sulfonic acid (AQS) dissolved in sulfuric acid, and a positive electrolyte containing bromine and hydrobromic acid. We find that the AQS cell exhibits a significantly lower capacity retention rate than the AQDS cell. The observed AQS capacity fade is corroborated by NMR evidence that suggests the formation of hydroxylated products in the electrolyte in place of AQS. We further cycle the AQDS cell and observe a capacity fade rate extrapolating to 30% loss of active species after 5000 cycles. After about 180 cycles, bromine crossover leads to sufficient electrolyte imbalance to accelerate the capacity fade rate, indicating that the actual realization of long cycle life will require bromine rebalancing or a membrane less permeable than Nafion® to molecular bromine.


Aceraceae acer becomes excellent tree species for urban greening by beautiful form, colorful leaves, diversified leaf shape and elegant outcomes. The paper introduces the cultivation history of compound leaf Aceraceae acer and its application to greening of landscape. Furthermore, favorable environment for its growth and measures for maturing management and pest control are elaborated.


In 2012, the Canton of Aargau launched the process for the development of its new long-term strategy 2013–2022 («Entwicklungsleitbild»). The development of a long-term planning poses a challenge for the executive authority since it involves setting the necessary course for an unknown future in the present; without a comprehensive and reliable factual foundation. Commissioned by the State Chancellery of the Canton of Aargau, the Institute of Public Management of the Zurich University of Applied Sciences – together with internal and external experts – established a foresight study. Models and instruments from trend research and futurology were adapted and applied to the specific tasks and challenges facing a cantonal administration. The emphasis was placed on trend, scenario and consequences analysis. As a result, recommendations for the three core political fields of action (society, economy and state) were formulated for the attention of the government.


During the investigation the concentrations of transforming growth factor beta 1 (TGF-β1) and tumor necrosis factor alpha (TNFα) in lacrimal liquor of 108 patients (160 eyes) with pseudoexfoliation glaucoma (PEG) of different stages in the compensating intraocular pressure (IOP) level were studied and their role in the development and progressing of this kind pathology was determined.Concentrations of TNFα and TGF-β1 in lacrimal liquor were found to be increased in pseudoexfoliation glaucoma patientscompared with the controls. There was a linear association between TFG-β1 levels and glaucoma stage.


Teaching is a profession characterized by an emotional burden. Anxiety, as a considerable emotion experienced, was found experienced not only frequently by in-service EFL teachers but also by pre-service EFL teachers. A high level of anxiety may cause problems in pre-service EFL teachers' academic and teaching performance. However, the study on pre-service EFL teachers' anxiety has been long marginalized within the field of EFL teachers in China. Reviewing the previous academic research results, the purpose of this study is to synthesize the primary research studies on pre-service EFL teachers' anxieties at home and abroad. For this purpose, academic papers published in journals that were recorded in Google Scholar, WOS (Web of Science), Elsevier, and JSTOR in foreign countries, and CNKI in mainland China were analyzed through content analysis. The findings showed that EFL teacher candidates experience high-level anxiety; the sources of anxiety can be categorized into social-cultural, affective factors, cognitive factors, and personal factors; it has physiological and psychological effects on their academic and teaching performance; studies on intervention measures indeed functioned well. As a result of the study, problems in research on pre-service EFL teachers' anxiety are identified. Recommendations and enlightenments to future research in China are discussed as well. At the end of this study, it also states the existing limitations and proposes a solution.


This paper reports the results of studying epoxy compositions with gypsum taken in the form of dispersed powders in the original and water-hardened form. The exact pattern has been shown in the way the introduction of a gypsum additive in the amount of 50 % by weight affects the strength, chemical stability, and morphology of the composites.

Under conventional heat treatment (60‒110 °C) of the hardened composites, the maximum stress at compression σm and the elasticity module at compression Ес, as well as wear resistance, decrease after the introduction of gypsums (of both types). At the same time, after a hard (destructive) heating at 250‒260 °C, the elasticity module Ес of the hardened composites increases. The maximum stress at compression σm is also increased. The same applies to the wear resistance, which grows especially noticeably after 250 °C.

The micro-hardness after filling is prone to increase but the fragility of epoxy-gypsum composites does not make it possible to measure it when a punch (a steel hemisphere) penetrates it deeper than 20 µm. However, after the heat treatment at 250‒260 °C, the unfilled polymer, on the contrary, is embrittled while the filled ones are plasticized, thus showing a high micro-hardness at significant (30‒50 µm) immersion.

The composites with gypsum, in contrast to the unfilled ones, do not disintegrate in acetone and retain integrity at any aging duration (up to 75 days and beyond). In this case, the original gypsum produces a composite with less swelling in acetone than the hardened gypsum. Based on the data from atomic-strength microscopy (ASM) microscopy, the morphologies of the non-filled composite, the composites with the hardened gypsum and original gypsum are different. The original gypsum forms a composite with a more pronounced (possibly crystalline) filler structure; the morphology for the hardened composite reflects the distribution of inert particles; for the unfilled composite (H-composite), only pores are visible against the background of a relatively smooth relief.


Given a square pencil $A+ \lambda B$, where $A$ and $B$ are complex matrices, we consider the problem of finding the singular pencil nearest to it in the Frobenius distance. This problem is known to be very difficult, and the few algorithms available in the literature can only deal efficiently with pencils of very small size. We show that the problem is equivalent to minimizing a certain objective function over the Riemannian manifold $SU(n) \times SU(n)$, where $SU(n)$ denotes the special unitary group. With minor modifications, the same approach extends to the case of finding a nearest singular pencil with a specified minimal index. This novel perspective is based on the generalized Schur form of pencils, and yields a competitive numerical method, by pairing it with an algorithm capable of doing optimization on a Riemannian manifold. We provide numerical experiments that show that the resulting method allows us to deal with pencils of much larger size than alternative techniques, yielding candidate minimizers of comparable or better quality. In the course of our analysis, we also obtain a number of new theoretical results related to the generalized Schur form of a (regular or singular) square pencil and to the minimal index of a singular square pencil whose nullity is $1$.


Pancreatic cancer and jejunal cancer are aggressive diseases with grim prognoses. The long term survival of pancreatic carcinoma is still one of the worst of all cancers. Ninety‐five percent of the patients die of their disease within 5 years [Wagener et al: Ann Oncol 5(Suppl 3): S87‐S90, 1994]. Eighty‐five percent of patients with jejunal carcinoma die of their disease within 5 years [Lioe, Biggart: J Clin Pathol 43: 533‐536, 1990]. To date, there are disappointingly few effective cytotoxic agents in the treatment of these cancers.


We propose a novel control method for lower- limb assist that produces a virtual modification of the mechanical impedance of the human limbs. This effect is accomplished through the use of an exoskeleton that displays active impedance. The proposed method is aimed at improving the dynamic response of the human limbs, while preserving the user's control authority. Our goal is to use active-impedance exoskeleton control to improve the user's agility of motion, for example by reducing the average time needed to complete a movement. Our control method has been implemented in a 1-DOF exoskeleton designed to assist human subjects performing knee flexions and extensions. In this paper we discuss an initial study on the effect of negative exoskeleton damping (a particular case of active-impedance control) on the subject's time to complete a target-reaching motion. Experimental results show this effect to be statistically significant. On average, subjects were able to reduce the time to complete the motion by 16%.


In this paper,we proposed a joint source channel coding method based on wireless channel prediction for FGS transmission.We use finite-state Markov channel to model the wireless channel,provide unequal loss protection for FGS coded stream according to its important difference.Then using the predictive result to optimize the channel coding in order to minimize the total code rate to transmit video under distortion constraints.Simulation results demonstrate effectiveness of our approach.


Part of coal resources in a mine in Yanzhou Coal Mining Area is under the river and coal is extracted by slice mining. In order to improve the upper limit of coal mining,the height of the waterflowing fractured zone of 53041 working face of this mine was determined as 51. 7 m by taking the coal mining of this face as the background and according to the ground borehole imaging observations; based on the actual strata data of the working face and through the analysis on the composition and structural characteristics of the seam roof and floor rock strata,the space development characteristics and development height of the waterflowing fractured zone after the slice mining of the thick seam were obtained by using FLAC3Dnumerical simulation, through the repeated calculations and correction and the analysis on the development characteristics of the seam roof water-flowing fractured zone; with the method by combining the site borehole imaging observation and numerical simulation,the height of the waterflowing fractured zone of the thick seam with slice mining was determined as 52 m,this research result provided an important reference basis for the improvement of the upper limit of coal mining under river and the reasonable retaining of the waterproof coal pillars.


This paper is about the contemporary debate concerning folk psychology–the debate between the proponents of the theory theory of folk psychology and the friends of the simulation alternative. At the outset, we need to ask: What should we mean by this term 'folk psychology'?


Studies on the effect of different secondary nutrients in different doses onthe quantity and quality of leaves of Terminalia arjunaunder 4' x 4' spacing revealedthat secondary nutrients have promotary effect in increasing the quantity andquality of leaves of tasar food plant T. arjuna. Among all the treatments understudy, foliar application of Magnesium sulphate (2%, w/v) is the best in respect ofincreasing the quantity and quality of leaves of T. arjuna. Under this treatment, leafyield increased by 26.20% over control. Chemoassay and bioassay results alsoconfirmed a significant improvement in the quality of leaf by the application of thesaid treatment.


OF DISSERTATION Validity Study of the Psychopathic Personality Inventory in a Noncriminal Population by Julie Madeleine Woltil Doctorate in Philosophy Candidate in Psychology Loma Linda University, September, 20 I 0 Todd Burley, Chair The Psychopathic Personality Inventory (PPI) is a self-repOli measure which was created by Lilienfeld and Andrews (1996) to identify the personality traits of psychopathy in noncriminal populations. These personality traits were grouped into eight subscales in the PPI including Machiavellian Egocentricity, Social Potency, Coldheartedness, Carefree Nonplanfulness, Fearlessness, Blame Extemalization, Impulsive Nonconformity and Stress Immunity. In this study, the relationship between the PPI and four theoretically related concepts (psychopathy, empathy, sensation seeking and driving anger) were examined to evaluate its concurrent and construct validity. A positive correlation was found between the PPI and the Self-Rep0l1 Psychopathy Scale, the Driving Anger Scale, the Amett Inventory of Sensation Seeking and the Interpersonal Reactivity Index. Contrastingly, a negative correlation was found between the PPI's Coldheartedness Subscale and the Interpersonal Reactivity Index. The results of this study have helped to further the conceptualization of the successful psychopath and the validity of the PPI in its assessment.


A new emphasis in cancer control has been evolving, one that provides a better framework for addressing the problems of cancer prevention and management prospec tively, through clearly defined phases. This emphasis derives in part from the recognition of a need for a national strategy to translate the rapid progress in basic knowledge about cancer into nationwide benefits. The new strategy gives the National Cancer Program an effector arm, a means of testing in human populations ideas that come from basic research but may be appropri ate to broader applications. The cancer control research process is now seen as a continuum. It begins with a systematic review of existing data from etiologic research and randomized treatment trials, proceeds through re search on intervention methods, then moves through cancer control intervention trials, both in prevention and in adoption and diffusion of "state-of-the-art" treatment. After trials demonstrate the efficacy of intervention, studies of defined populations are conducted to deter mine the potential benefits for target groups or society as a whole. These studies identify barriers to adoption in the "real world," and methods to overcome these barriers to achieve widescale use of proven techniques. In 1982, NCI's Division of Cancer Prevention and Control (DCPC) conducted a comprehensive review of cancer control research opportunities. Among the out comes of that activity were a revised statement of the research objectives of DCPC's programs and a reorganiza tion of the Division in keeping with these new program directions, developed with the advice of the Division's Board of Scientific Counselors. A recent product of this review is a one-sentence definition, which we feel captures the meaning of cancer control: "Cancer control is the reduction of cancer incidence, morbidity, and mortality through an orderly sequence from research on interventions and their impact in defined populations to the broad, systematic application of the research results. " Note that this definition refers both to cancer control research-that is, research on interventions-and to the application of the research results. This definition will be explained in more detail later. Concurrently, a new attitude has been developing among cancer control investigators: That cancer control needs a cutting edge of objectivity. Such objectivity depends on research-research on interventions, and especially research which can have a broad community impact of lowering cancer rates. As with other scientific experiments, cancer control research follows the scien tific method: Formulation of hypotheses, close observa tion, measurement, and quantitative analysis are the means of drawing inferences. An effective bridge from basic studies to the utilization of the study results requires, in itself, research; this applied research often falls within the arena of cancer control research.


For storing a word or the whole text segment, we need a huge storage space. Typically a character requires 1 Byte for storing it in memory. Compression of the memory is very important for data management. In case of memory requirement compression for text data, lossless memory compression is needed. We are suggesting a lossless memory requirement compression method for text data compression. The proposed compression method will compress the text segment or the text file based on two level approaches firstly reduction and secondly compression. Reduction will be done using a word lookup table not using traditional indexing system, then compression will be done using currently available compression methods. The word lookup table will be a part of the operating system and the reduction will be done by the operating system. According to this method each word will be replaced by an address value. This method can quite effectively reduce the size of persistent memory required for text data. At the end of the first level compression with the use of word lookup table, a binary file containing the addresses will be generated. Since the proposed method does not use any compression algorithm in the first level so this file can be compressed using the popular compression algorithms and finally will provide a great deal of data compression on purely English text data.


Abstract 5086 Purpose of the study: We observed an increased frequency of hematologic malignancy (HM) in patients and family members of patients with renal cell cancer (RCC) and sought to characterize the association further in terms of frequency and characteristics of HM, and the importance of such an association. Methods: We performed a chart review of our data base of approximately 700 RCC patients seen by us from 2004 to the present in an effort to determine the frequency of HM in patients and in the families of patients diagnosed with RCC. Results: Of the 700 charts reviewed, both HM and RCC occurred in 19 individuals. [11 males and 8 females]. HM diagnosis included acute myeloid leukemia in 1 patient, Hodgkin9s lymphoma (HL) in 4 pts, non-Hodgkin lymphoma (NHL) in 7 pts, (3 small cell and 4 large B-cell lymphoma), chronic lymphocytic leukemia (CLL) in 2 pts and hairy cell leukemia (HCL), monoclonal gammopathy of undetermined significance (MGUS) myelodysplasia (MDS) in one patient each. A family history of HM was found in 71 relatives involving 56 families of patients with RCC. Of these, 48/71 cases of HM were in first degree relatives and 18/71 were in second degree relatives. The most common HMs were lymphoma and leukemia: 24 NHL, 9 HL, 6 lymphoma not further specified (NOS), 11 CLL, 1 acute myeloid leukemia, 5 acute leukemia NOS and 6 leukemia NOS. Other HM observed once were multiple myeloma, Waldenstrom9s macroglobulinemia, chronic myeloid leukemia, myelofibrosis and polycythemia vera. In addition, 2 family members had blood cancers that were NOS. Thus, of 77 patients/family members with known HM diagnosis 94% were B-cell malignancies. Clear cell histology was the most common subtype of RCC, and all subtypes of RCC occurred in the study population with expected frequency. RCC and HM occurred in the same patient in this study more frequently at 2. 7% than would be expected from a SEER database. In that database the observed to expected (O/E) ratio of NHL and RCC was 1. 86 to 2. 07% [Kunthur et al. Am J Hematol 2006; 81:271–80]. Conclusions: Increased incidence of B-cell malignancy has been reported in individuals with RCC [Dutcher et al. Proc Am Fed Clin Res, Eastern Division, April 2011]. Wiernik et al. [Cancer J 2000] reported a similar increase was noted between adenocarcinoma of the breast and B cell malignancies in same individual and mouse mammary tumor virus was proposed a potential causative agent. There is a preponderance of B-cell malignancy in both the individuals and in the families of the patients with RCC noted in this study. The etiology of this association between RCC and HM is unclear and suggests a common etiopathogenesis for RCC and B-cell tumors, or a familial immunologic defect that facilitates both malignancies. We plan to further explore the relationship of HM to RCC. Disclosures: No relevant conflicts of interest to declare.


Review(s) of: The origins of the Irish, by J.P. Mallory, Thames and Hudson, 2013, 320 pages, $29.99; Celts: Art and identity, by Julia Farley and Fraser Hunter (eds.), British Museum Press, 2015, 304 pages, 25 pounds.


Histidine protein kinases (HKs) are prevalent prokaryotic sensor kinases that are central to phosphotransfer in two-component signal transduction systems, regulating phosphorylation of response regulator proteins that determine the output responses. HKs typically exist as dimers and can potentially autophosphorylate at each of a single conserved histidine residue in the individual protomers, leading to di-phosphorylation. However, analyses of HK phosphorylation in biochemical assays in vitro suggest negative cooperativity, whereby phosphorylation in one protomer of the dimer inhibits phosphorylation in the second protomer, leading to ~50% phosphorylation of the available sites in dimers. This negative cooperativity is often correlated with an asymmetric domain arrangement, a common structural characteristic of autophosphorylation states in many HK structures. In this study, we engineered covalent dimers of the cytoplasmic domains of Escherichia coli CpxA, enabling us to quantify individual phosphorylated species: unphosphorylated, monoand di-phosphorylated dimers. Together with mathematical modeling, we unambiguously demonstrate no cooperativity in autophosphorylation of CpxA despite its asymmetric structures, indicating that these asymmetric domain arrangements are not linked to negative cooperativity and hemi-phosphorylation. Furthermore, the modeling indicated that many parameters, most notably minor amounts of ADP generated during autophosphorylation reactions or present in ATP preparations, can produce ~50% total phosphorylation that may be mistakenly attributed to negative cooperativity. This study also establishes that the engineered covalent heterodimer provides a robust experimental system for investigating cooperativity in HK autophosphorylation and offers a useful tool for testing how symmetric or asymmetric structural features influence HK functions. _______________________________________ Two-component systems (TCSs), the prevalent signaling pathways in bacteria, are one of the best studied models of signal transduction schemes (1,2). A conserved phosphotransfer reaction between the sensor histidine kinase (HK) and the response regulator (RR) is used to couple a large variety of inputs and outputs. HKs, usually functioning as homodimers, sense stimuli through their variable sensing domains and modulate phosphorylation levels of their cognate RRs. HKs display multiple enzyme activities, including autokinase, phosphotransferase that is catalyzed in conjunction with the RR protein, and often phosphatase activity toward the phosphorylated cognate RR. The conserved catalytic core of an HK consists of a dimerization and histidine phosphotransfer (DHp) domain that contains the https://www.jbc.org/cgi/doi/10.1074/jbc.RA120.012757 The latest version is at JBC Papers in Press. Published on February 24, 2020 as Manuscript RA120.012757 by gest on M ay 7, 2020 hp://w w w .jb.org/ D ow nladed from Phosphorylation of histidine kinase CpxA is not cooperative 2 conserved histidine residue for receiving and transferring the phosphoryl group, and a catalytic ATP-binding (CA) domain that contains residues critical for kinase activity. Structures of HKs and HK-RR complexes representing different enzymatic states have been captured, providing mechanistic details of HK activities. Signaldependent regulatory mechanisms have been investigated for HKs in response to ligand binding (3-6) or light sensing (7,8). The structures and mechanisms have been extensively reviewed (2,912). Distinct structural features are often linked to individual catalytic functions and biochemical behaviors of HKs. Except for several atypical HKs with unusual oligomeric or monomeric states (13-15), one predominant emerging theme in HK signaling is the symmetry/asymmetry transitions in HK dimer structures. The symmetric or asymmetric HK structures involve similar or different arrangements of structural elements between individual protomers within an HK dimer. Structures with both symmetric and asymmetric conformations have been observed in the periplasmic sensing domains (3-5), the signal-transducing transmembrane helices and HAMP domains (6), and the catalytic core domains (16-20). Transitions between the two conformations have often been associated with signal-dependent switching of HK activities (16-18). Bhate and colleagues (10) analyzed more than 20 HK structures and revealed a general trend of symmetry/asymmetry transitions in different HKs. Symmetry or asymmetry in the catalytic core domains refers to the packing of DHp helices and the relative positioning of the two CA domains. While the phosphatase state of an HK is often symmetric, with two CA domains held at positions unfavorable for phosphorylation, the autokinase state harbors an asymmetric conformation with one CA domain in close proximity of one phosphorylatable histidine whereas the other CA domain is located far from the other histidine. The CA domain that provides the reactive ATP and the histidine receiving the phosphoryl group can be from the same or different protomers, resulting in a cis or a trans phosphorylation mechanism in different HKs. Nevertheless, both mechanisms make use of similar asymmetric conformations that only allow phosphorylation of one histidine at a time (16,17,19,21,22). Such asymmetric structures are often intuitively associated with asymmetric phosphorylation, in which phosphorylation of one protomer hinders phosphorylation of the second protomer, leading to hemi-phosphorylation in the extreme case, with a single phosphorylation event per dimer. For example, observation of asymmetric conformations in CpxA led to implication of hemiphosphorylation despite the experimental observation of a 70% total phosphorylation level, where the phosphorylation exceeding 50% was attributed to subunit exchange of protomers within HK dimers (17). As structural asymmetry is repeatedly demonstrated for the kinase state, is phosphorylation asymmetry also a general trend in HKs? Asymmetric phosphorylation, or negative cooperativity, has been biochemically explored in several HKs (19,23,24). Early studies on NRII indicated that the equilibrium constant for phosphorylation of the first protomer is ~78 fold larger than that of the second protomer (23). Negative cooperativity has been attributed to an exceptionally rapid reverse reaction with transfer of the phosphoryl group from the di-phosphorylated HK to ADP generating the hemi-phosphorylated HK, thus ADP has a large inhibitory effect on diphosphorylation of HK dimers. Hemiphosphorylated HKs have also been observed on native gels in studies of HK853 (19). A complete di-phosphorylation of HK853 dimers was not achieved unless ADP present in the reaction mixture was continuously recycled back to ATP. An even stronger negative cooperativity has been demonstrated for DesK (24). The observed phosphorylation stoichiometry of DesK was ~0.5 and full phosphorylation was not achieved even in the presence of a coupled enzyme system that continuously converted ADP to ATP, indicating an extremely high negative cooperativity. Such extreme negative cooperativity may be uncommon for HKs because full phosphorylation at high ATP levels or in the presence of ATP regeneration has been documented for many HKs (19,23,25,26). On the other hand, analyses of the hybrid HK ShkA indicates no cooperativity in autophosphorylation (25). Biochemical analyses of negative cooperativity of phosphorylation often rely on deriving equilibrium constants by measuring HK phosphorylation levels across a wide range of ATP by gest on M ay 7, 2020 hp://w w w .jb.org/ D ow nladed from Phosphorylation of histidine kinase CpxA is not cooperative 3 concentrations. However, likely due to the spontaneous hydrolysis of ATP, even the "high purity" commercial ATP reagent contains trace amount of contaminating ADP (26-28). The initial amount of ADP, relative to that generated during the phosphorylation reaction, is non-trivial when high concentrations of ATP are used. Under such conditions, the inhibitory effect of the contaminating ADP might not be negligible, as presumed in prior analyses, and could impact interpretation of negative cooperativity. Here we take account of the initial ADP concentration in the kinetic equilibrium modeling and show that the neglect of ADP contamination can lead to significant overestimation of negative cooperativity. We develop a strategy to examine the phosphorylation cooperativity by measuring the un, monoand di-phosphorylated HK dimer species using a covalently linked HK dimer. Applying this strategy to E. coli CpxA, we demonstrate that autophosphorylation of CpxA is not negatively cooperative, or asymmetric, despite the structural asymmetry.


The professionalism and skill of animation screenwriting is an important content of animation film research. The scree nwriter of animation film designs the plot rhythm blueprint for the future film. The director uses montage to recreate o n the basis of this blueprint. This paper discusses the plot design of animation drama, including conflict, sudden turn a nd misunderstanding, and also analyzes the important role of the supporting point of the plot in animation drama.


Training strategy is a vision, direction, action, planning for training and development in an organization that requires implementation to achieve success. The study assessed the training strategies preferred by the horticulture extension personnel for attending trainings in Jammu region of Jammu and Kashmir. A total of 200 horticulture extension personnel (Horticulture development officers and horticultural technicians) were sampled for obtaining training by proportionate stratified random sampling technique. Data were analysed by using frequency and percentage. The finding of the study revealed that more than one half (63%) horticulture development officers and 53 per cent horticulture technicians preferred 3–5 days training programme. Majority (60%) Horticulture development officers (HDOs) preferred SKUAST-J Chatha and about one half (45%) horticulture technicians preferred their respective district head office/KVKs as venue for attending training programme. Both horticulture development officers and horticulture technicians preferred to attend training programme in the month of October-December. Trainers for training from outside state were preferred by more than one half (53%) horticulture development officers where trainers out of their parent organisation but within the state were preferred by 3/4th of the horticulture technicians for obtaining trainings, respectively. Method as well as result demonstration techniques were perceived as very effective training methods. Major constraint expressed by horticulture development officers was shortage of staff, where pay anomalies, excess work load and lack of promotional avenues were major constraint expressed by the horticulture technicians in performing their job.


Detection of strangelet is an important goal in the field of cosmic rays. It is also important for our understanding of the physics and astrophysics of strongly interacting matter. In our present work, we have used Solid State Nuclear Track Detectors (SSNTDs), which, being passive detectors, offer an alternative low cost detector option, to look for such rare events in cosmic rays. We have placed CR-39 along with Polyethylene Terephthalate (PET) to study the background radiation at mountain altitudes and variations in detector response with different environmental conditions. Observations for the present work have been made at different mountain altitudes. Some preliminary results of the study are presented here.


A single base substitution mutation from guanine to cytosine was constructed at position 2661 of Escherichia coli 23S rRNA and cloned into the rrnB operon of the multi‐copy plasmid pKK3535. The mutant plasmid was transformed into E.coli to determine the effect of the mutation on cell growth as well as the structural and functional properties of the mutant ribosomes in vivo and in vitro. The results show that the mutant ribosomes have a slower elongation rate and an altered affinity for EF‐Tu‐tRNA‐GTP ternary complex. This supports previous findings which indicated that position 2661 is part of a region of 23S rRNA that forms a recognition site for binding of the ternary complex in the ribosomal A site. Combinations of the 2661 mutation with various mutations in ribosomal protein S12 also demonstrate that elements of both ribosomal subunits work in concert to form this binding site.


Prion removal evaluation of plasma processing procedures is one important basis to assess the margin of safety of plasma protein therapeutics. Currently, in these evaluation studies to assess the removal capacity of selected manufacturing steps for human prions mainly prions derived from scrapie-infected hamsters or mice are used in spiking studies. In order to test the validity of hamster prions instead of different human prion strains as spiking reagents, we compared the partitioning of these prion preparations at two purification steps common to the manufacturing of several human plasma-derived therapeutic proteins at ZLB Behring. The glycine precipitation (inherent in the manufacture of e.g., vWF/Factor VIII) and the 25% ethanol precipitation step (inherent in the manufacture of e.g., alpha-1-proteinase inhibitor and albumin) were down scaled to mimic the production process. A microsomal membrane preparation as well as purified full-length pathogenic prion (PrPSc; without membrane association) prepared (a) from hamster brains infected with the model scrapie strain Sc237, (b) from brains of transgenic mice infected with human sporadic CJD prions, and (c) from the brain of a patient who died of vCJD were used for spiking experiments. The different prion preparations were spiked to the starting material of the manufacturing steps studied and the manufacturing step was performed in a dedicated laboratory. The amount of PrPSc in all fractions was determined quantitatively utilizing an ELISA-formatted Conformation Dependent Immunoassay [Safar et al., Nat Med 1998; 4 1157–1165]. The 25% ethanol precipitation removed very effectively all prion preparations equally regardless of their origin (reduction factor ≥ 3 log10). The glycine precipitation removed the microsomal as well as the purified prion preparations from all species equally whereby prions of the purified prion preparation were removed to a considerably higher degree than the membrane preparation (reduction factor ≥ 3 log10 vs. 1.6 to 1.8 log10). In parallel, prion infectivity of each sample is currently tested in animal bioassays involving transgenic mice susceptible for the tested prion strain. It can be concluded, up to now based on immunological data, that spiked hamster prions are a reliable model to confirm the safety of human plasma-derived products also for human derived prions.


A key element in many of the most recent educational reform movements has been to increase parental involvement in the academic lives of children. Aside from the intuitively appealing notion of parents being more actively involved in their child's education, a plethora of research data has been generated which generally supports this proposition. For example, reviews of preschool and school-based family intervention programs have documented immediate improvements in standardized achievement test scores (e.g., Goodson & Hess, 1976; Graue, Weinstein, and Walberg, 1983), while other studies have found evidence for the effectiveness of specific intervention strategies on skills such as reading (e.g., Hewison, 1988). A variety of non-cognitive indicators such as dropout rates, parental feelings of self-efficacy, and parental attitudes toward school have also shown improvements as a result of involvement programs (see, for example, Epstein, 1986; Henderson, 1987, Cochran & Dean, 1991). Although not all research has clearly supported the efficacy of parental intervention programs (e.g., White, Taylor & Moss, 1992), a recent review of research aimed at identifying factors which most influenced student learning found that the home and community environment was a significant contributor to student success (Wang, Haertel, & Walberg, 1993). According to these authors: "The home functions as the most salient out-of-school context for student learning, amplifying or diminishing the school's effect on learning" (Wang, et al., 1993, p. 278). A direct result of this renewed interest in parental involvement has been an explosion of programs, activities, and suggestions designed to increase the influence of parents in their children's lives. But, while many activities are certainly worthwhile, as Rasinski and Fredericks (1989) point out, "they often lack an overall organization that allows teachers to plan and develop principled programs for parents" (p. 180). The purpose of this paper is to present a model for parental involvement which will provide an organizational structure for involvement programs. While there have been attempts in the past to construct frameworks and category systems, what is unique about the present approach is the use of "parental empowerment" as a guiding theoretical theme. Recent discussions of involvement programs have emphasized the importance of enabling parents to have more control over their own lives. The model presented here provides a framework for thinking about empowerment that is organized into a hierarchical, developmental structure. Before discussing the model in detail, though, it may be helpful to the reader to view empowerment within a historical context. The following section will provide a brief history of parental involvement along with a rationale for the proposed model. Parental Involvement in Historical Context The increase in societal influence over children's lives has become more pronounced during the past 100 years due, in large part, to the institution of formal, compulsory education. Mann and Blackwell (1992) describe the rise in societal responsibility as resulting in a corresponding decline in the parental role. As these authors put it: "Parents gradually became more reliant on the school's judgement and the school's attempts to understand their children's abilities, personalities and intellectual potential" (Mann & Blackwell, 1992, p. 287). Beginning in the 1960's, however, policy-makers began to recognize the importance of early (pre-school) intervention as a means for improving the lives of disadvantaged or "at risk" children. Kellaghan, Sloane, Alvarez & Bloom (1993) have outlined the evolution of home intervention programs as a progression from a deficit model approach in the 1960's to a "difference model" in the 1970's and early 1980's to the current trend of "empowerment models." What is most interesting about their review is the manner in which perspectives have changed to both understand and meet the needs of at-risk families. …


Objective To construct three soluble HBV-HLA-A*0201-peptide complexes and detect the HBV-specific cytotoxic T lymphocytes(CTL)by using the constructed HLA-A*0201-peptide tetramers.Methods Proteins of HLA-A*0201-BSP and β2m were obtained by effective prokaryotic expression.After being purified,the proteins were refolded into HLA-A*0201-β2m-peptide complexes in the presence of three antigenic peptides(Hepatitis B virus Core18-27,Env335-343,and Pol575-583)by dilution method.The complexes then were biotinylated by BirA enzyme and purified via the gel-filtration chromatography.Tetramers were generated by mixing the complex with PE-Streptavidin at a molar ration of 5∶1.Then analysis of stained PBMCs was performed using FACScan and CellQuest software.Results The biotinylated HLA-A*0201 complexes were identified by Western blotting and were shown to have the natural conformation by Dot-ELISA.The constructed HBV-HLA-A*0201-peptide tetramers were capable of detecting the HBV-specific CTLs in patients with self-limited acute HBV infection,The tetramer-positive cells specific for the core18-27 epitope were found at a higher frequency than those specific for polymerase 575-583 and envelope 335-343 epitopes.Conclusion The biotinylated HLA-A*0201-peptide complexes is constructed successfully,which can be used to detect the specific CTLs.


Prepublished online March 26, 2014; Erik Arner and Andreas Lennartsson Lassmann, Piero Carninci, Yoshihide Hayashizaki, Alistair R. R. Forrest, Albin Sandelin, Karl Ekwall, Lehmann, Ilka Hoof, Michiel de Hoon, Masayoshi Itoh, Sayaka Nagao-Sato, Hideya Kawaji, Timo Michelle Rönnerblad, Robin Andersson, Tor Olofsson, Iyadh Douagi, Mohsen Karimi, Sören reveal timed changes and dynamic enhancer methylation Analysis of the DNA methylome and transcriptome in granulopoiesis http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found online at: http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#reprints Information about ordering reprints may be found online at: http://bloodjournal.hematologylibrary.org/site/subscriptions/index.xhtml Information about subscriptions and ASH membership may be found online at:


BACKGROUND
Although liaison services in acute hospitals are now the norm, the reverse is not usually available for patients in mental health trusts. Following the introduction of support from geriatricians to older people's mental health inpatient wards, we wanted to see if this intervention was effective and acceptable to clinicians.

METHODS
We performed a retrospective cohort service evaluation on the impact of a liaison geriatrician, using routinely collected data, and assessed acceptability among medical staff by semi-structured interview.

INTERVENTION
Our service introduced regular sessions from consultant community geriatricians across older adults psychiatric wards including a mixture of video conference and face-to-face input.

RESULTS
There was no significant decrease in emergency transfers but there was a significant reduction in length of stay with an associated cost benefit for the service after the introduction of a liaison geriatrician. There was a significant increase in geriatrician consultations and a decrease in specialty consultations to other specialists. There was no change in discharge prescriptions or destination. There was a significant reduction in falls in the intervention arm but not in falls leading to emergency hospital admissions geriatricians gave confidence to psychiatrists of all grades to treat physical health care issues.

CONCLUSIONS
A liaison geriatrician service may be a component in reducing length of stay (although there are many others) and improving continuity of care, although it confers no impact on emergency transfers. The intervention was highly acceptable to clinicians.


A common misunderstanding of the Abortion Act 1967 is that it granted women the 'right' to access abortion. In reality, there is no such thing; the current provision of abortion in the United Kingdom rests on a system in which doctors, not women, are the arbiters of abortion access. In recent years, calls for the full decriminalisation of abortion have been given a vigour not seen before. For the first time, MPs and medical associations have moved to back decriminalisation, in line with the demands of pro-choice campaigners across the UK. But at the same time, opponents are mobilising to undermine public faith in both the Abortion Act and abortion providers. In doing so, they have tended to set aside the classic 'right to life' arguments, instead focusing on issues such as sex-selective abortion and disability rights. This book makes sense of today's changed landscape of abortion debate by tracing the evolution of political and parliamentary discourse on abortion from the passage of the Abortion Act in the 1960s to the present. It makes the case that to understand contemporary abortion politics, it is necessary to move beyond a conceptualisation of the debate as characterised by 'pro-choice' versus 'pro-life'.


Flood is an intense and recurrent natural hazard in the eastern and north-eastern part of India. The mighty Ganges, Brahmaputra and Barak rivers flow in this region and their seasonal flooding results in extensive damage to life and property. The eastern region of India comprising eastern Uttar Pradesh, Bihar, West Bengal, Assam and other north-eastern states is economically the most backward and poverty-stricken. Paradoxically this region happens to be richly endowed with natural resources, with almost 40 percent of the nation's mineral resources and 60 percent of its power potential. However, the region suffered severe floods in 1954, 1974, 1975, 1976, 1984, 1987, 1988, 1993, 1998 and 2000. Thus, water, which can potentially deliver untold benefits through multi-sectoral development, actually jeopardizes local developmental activities. The rightful prosperity of the region has to be based on the critical and vital role that water resources of the region play. The region accounts for 50 percent of the country's land surface, 42 percent of its population, 61 percent of its flood-prone area and 85 percent of its flood losses. To mitigate flood losses, mostly earthen embankments (13 577 km), drainage channels and a number of town protection works have been undertaken. These measures have provided a reasonable degree of protection to only half of the region's flood-prone area. Several non-structural measures, such as flood forecasting and warning and flood-proofing programmes, have also been taken. During high floods, many breaches occur, causing inundation over vast areas for most of the monsoon months of June to September. Studies show that flood levels up to two metres high could be contained in the Brahmaputra River and the severity of floods substantially reduced, in combination with the generation of hydropower of about 30 000 megawatts. Most of the suitable dam sites are located in neighbouring Nepal and Bhutan. The reservoir sites in Nepal are eminently suited to the construction of storages and development of water resources for both Nepal and India. Negotiation is going on between the two countries for the joint development of water resources for storage and watershed management, which could be most effective with people participation at all levels. This paper deals with the effectiveness of the measures taken so far and with the future strategy to lessen the adverse impact of floods on socioeconomic conditions with special emphasis on participatory flood management and flood loss mitigation preparedness programmes. The participatory flood management measures could be: (1) construction of embankments on a selective basis; (2) maintenance of embankments; (3) watershed management at micro and macro levels; (4) land use regulation; (5) soil conservation and afforestation; (6) flood emergencies; (7) disaster management and preparedness; (8) flood forecasting, issuance of warnings and their quick dissemination through signals; (9) change in cropping patterns; and (10) a flood-proofing programme. ∗ The views expressed herein are those of the author and do not necessarily reflect those of the Indian government or of the United Nations.


Object To analyze the incidence and risk factors of microembolic lesions on MR diffusion-weighted imaging (DWI) after endovascular coiling of unruptured intracranial aneurysms (UIA). Methods We analyzed data obtained from 271 consecutive patients (70 men and 201 women; median age 57 years, range 23–79 years) who presented with UIA for coil embolization between July 2011 and June 2013. Two independent reviewers examined DWI and apparent diffusion coefficient (ADC) maps obtained the following day for the presence of restrictive diffusion spots and counted the number of spots. A multivariate analysis was then performed to identify independent risk factors for developing microembolism following coiling of an aneurysm. Results Microembolic lesions were noted in 101/271 patients (37.3%). Results of a multivariate analysis showed that the following factors significantly influenced the risk for a microembolism: age, diabetes, previous history of ischemic stroke, white matter FLAIR high signal lesions, multiple aneurysms, and insertion of an Enterprise stent (all ORs > 1.0 and all P-values Conclusion The incidence of microembolism after endovascular coiling of UIA was not low. Lesions occurred more frequently in patients with vascular status associated with old age, diabetes and previous stroke. The multiplicity of aneurysms and the type of stent used for treatment also influenced lesion occurrence. Disclosures J. Park: None. D. Lee: None. J. Ahn: None. B. Kwun: None.


Objective To evaluate the clinical outcomes of combined reconstruction of anterior cruciate ligament(ACL) and posterior cruciate ligament(PCL) with allogenic patellar tendons.Methods 39 patients of combined ACL and PCL injury were enrolled in this study,in which 28 cases were combined with medial collaternal ligament injuries and 2 cases with lateral collaternal ligament injuries.All the ACL and PCL were reconstructed with allogenic patellar tendons,fixed with interference screws and the combined injuries were treated at the same time.38 cases were followed up 7~48 months with an average of 18 months,only 1 case lost follow up.Results The clinical outcomes were evaluated with Lysholm knee scoring system,the average score were 84 points postoperatively compared to 22 points preoperatively.There were no complications injures or rejection reactions occurred and the knee flexion were 100°~120°without restrictions.All the patients regained normal work and daily life movements after 6-8 months.Conclusion Reconstruction of ACL and PCL with allogenic patellar tendons arthroscopically could regain the functions and stability of the knee joints with satisfactory outcomes.


Abstract Berberine(BER) binds to the double helical DNA with a high affinity There is only a much smaller hypochromism and no shifts in the absorption spectra when BER binds to calf thymus DNA(CT DNA) The fluorescence yields increase dramatically when BER binds to DNA, with no shifts in the emission maximum. These spectral changes are in contrast to the behavior observed with many fluorescent intercalates Groove binding rather than intercalation was suggested to be the cause of these spectral changes. Consistent with groove binding, for polyamide anion quenching studies showed that the magnitude of Ksv of the bound BER was higher than that of the free BER. The addition of salt to the solution releases the DNA-bound drug action from the groove and causes a decrease in the fluorescence yield. The results of all above studies proved the groove binding of BER to DNA. The large fluorescence enhancements observed when BER binds to DNA and the poor fluorescence yield of BER in the absence of DNA can be used for ...


It is obtained a Wold-type decomposition for an adjointable isometry on a Hilbert C∗-module which is sequentially complete with respect to some locally convex topology, denoted by s. Particularly self-dual Hilbert C∗-modules satisfy this condition. Finally, as an application we shall give a new proof of the Wold decomposition theorem for discrete stationary processes in complete correlated actions.


To date no study has prcscnted data. which systematically consIder the detailed activity of foreign direct Invcstment (FDI) in Turkey ovei- a substantial period of time. Drawing on official sources, this paper attempts to rectify this position by providing key statistIcs on the trend and pattcrn of foreign equity venture formation in Turkey. The study e.xamines several dimensions of activity: Time period of formation: industry characeristics: geographical location, capital size, foreign equity shareholding, and company type. An attempt is made to explore [he percentage of foreign ownership of foreign investments in Turkey by means of regression analysis.


The purpose is to observe the clinical effects of sodium hyaluronate injection plus herbal fumigation in the treatment of knee osteoarthritis. 58 patients(73knees)were treated by sodium hyaluronate injection plus herbal fumigation with a treatment course of five weeks and after a fellow-up of 6–36 months, the average fellow-up time was 12.1 months, the curative effect showed that 39 patients was excellent (52knees), 11 patients was fine (15knees), 4 patients was midst (5knees), 1 patient was bad (1knees), and the total fineness rate was 91.78%. Sodium hyaluronate injection plus herbal fumigation in the treatment of early metaphase of knee osteoarthritis, which had a better curative effect, less adverse reaction, and worth to extend clinical application.


It could not only maintain and develop the characteristics of traditional Chinese gynecolo- gy teaching but also assimilate the predominance of western medicine gynecology teaching through the inte- gration of traditional Chinese medicine and western medicine in the process of traditional Chinese gynecolo- gy teaching,which could make the teaching much closer to the clinical practice and hence train gynecolo- gists proficients of both traditional Chinese medicine and western medicine.


The flow of water in the middle and surface layers around and over a lake bar was examined in terms of horizontal and vertical velocities, and divergence. These quantities were mapped and the patterns correlated with the general current velocity, wind conditions, and obstruction by the bar.

1) The bar caused two types of flow around it. In the unstratified layer above the thermocline the flow continued right over the bar, although the exact pattern of motion depended upon the current speed and the geography of the bar.

2) In the thermocline there was a strong tendency for the water to flow around the bar, although considerable upwelling and sinking of the layer occurred. Helical rotors appeared on either side of the bar.

3) Internally consistent and detailed patterns of circulation were observed on a small scale without excessive expenditure of time or money.


Due to changing requirements and increasing engineering efforts of manufacturing systems, methods such as plug and produce gain in importance. The ability to adapt to varying product variants and new manufacturing modules can be achieved through cyber-physical production systems. In this context orchestration, the process of selecting suitable manufacturing modules, is a major aspect. Current approaches mostly focus on a functionality matching, not taking into account continuous system aspects such as throughput or energy consumption. This paper presents a two-stage orchestration approach for modular cyber-physical production systems. The manufacturing modules are semantically described regarding their functionality, system interfaces and continuous system behavior. Based on a high-level production process specification, possible variants of actual manufacturing systems are determined. The orchestration algorithm uses weighted scoring functions to calculate the matching degree and thereby enables a ranking. In order to match continuous system behavior and to use it as criterion for orchestration, Semantic Behavior Models (SBM) are introduced.


This study examined the attitudes of older workers towards work and retirement, retirement planning and their willingness to continue working after retirement and to undergo retraining. Data were collected via questionnaire surveys. Respondents consisted of 204 individuals aged 40 and above who attended courses at a local institute of labor studies. Findings suggested that work occupied a salient part of the respondents' lives. In general, respondents also held rather ambivalent attitudes with regard to the prospect of retirement, i.e. while they did not view retirement negatively, they were nevertheless anxious about certain aspects of retirement. Results also suggested that majority of respondents preferred to remain employed in some ways even after they have officially retired from the workforce, i.e. partial rather than full retirement was preferred. Implications of findings for organizations and policy makers were discussed.


ABSTRACT
Maxwell Alexandre was born, lives, and works in Rio de Janeiro, a resident of Rocinha, one of the biggest slums of Latin America. This paper pursues the relation of Maxwell Alexandre's paintings, from his relationship with the colors. Part of that concernment is due to one of the artist' series called "Pardo e paper". Maxwell presents a homonym exhibition in Lyon, Rio de Janeiro, and Porto Alegre. In a few years of production, the artist turns one of the most important references to Brazilian art and, mainly, makes part in the young Afro-descendant scene of art. Ethnic racial relations, black people empowerment, hip hop music universe, there are many possible connections between Maxwell Alexandre's production and the recent production of the art, music, and society with the markers of race and class. The color dialogues with publicity elements and regulatory institutions, as the city police and the public school, as well as the Rio de Janeiro's flag. In another way, the paper pursues to discuss the racial theories and the possibility of an Afro-descendant artist to deal with an element, the color, so related to a racist and excluding art system.


BACKGROUND: Health and nutritional assessment of the institutionalized geriatric population is essential in providing better health care. OBJECTIVE: To assess the institutionalized geriatric population's nutritional and mental health status. METHODOLOGY: One hundred elderly people aged 60 years and above residing at Little Drops – Old Age Home, Mangadu, Kanchipuram District, Tamil Nadu, were selected for the study. General information was obtained using a structured interview schedule. Nutrient intake was assessed using the three day dietary recall method. Standard methods were used to measure anthropometric, biochemical, and clinical parameters. Mental health was assessed using the Depression, anxiety, and Stress Scale (DASS-42) tool. RESULTS: Noncommunicable diseases such as hypertension (37%), osteoporosis (35%), and type 2 diabetes mellitus (25%) were reported by the participants. Walking and hand exercises were the most common form of physical exercise. The mean height, weight, and body mass index were 153.55 ± 11.83 cm, 55.49 ± 14.21 kg, and 23.83 ± 6.50 kg/m2, respectively. The mean systolic blood pressure and diastolic blood pressure were 128.61 ± 21.12 mmHg and 80.37 ± 10.70 mmHg, respectively. The mean hemoglobin value of male and female participants was 11.90 ± 2.33 g/dL and 11.09 ± 1.92 g/dL, respectively, thus indicating the presence of anemia. The intake of macro and micronutrients was less than the recommended dietary allowances. The decrease in food intake was due to tooth problems, xerostomia, difficulty in swallowing, nausea, and vomiting. Based on the scores obtained using the DASS-42 tool, most of the participants (70%) were depressed. CONCLUSIONS: The results specify the need to conduct periodical medical screening programs to improve the health status of geriatric people.


Using the same electrolytic bath in the electrolytic tank and the hydrogen generator. According to one embodiment, the electrolytic cell comprises a frame body having an interior. To divide the interior into two chambers, a proton exchange membrane (PEM) is provided inside the frame body. Inside the frame is provided away from the PEM anode in the form of a gas diffusion electrode, the space between the anode and PEM is filled with an aqueous solution of sulfuric acid. Inside the frame a cathode is provided, it is ionically bound to PEM. In use, the sulfuric acid solution side of the anode sulfur dioxide is supplied to the opposite side, a current is supplied to the electrolytic cell. As a result, the sulfur dioxide is oxidized at the anode, molecular hydrogen is produced at the cathode. .Field


Cotton, a plant of the Malvaceae family, is cultivated today in Brazil in three macro regions: the North– Northeast (the states of Tocantins, Maranhão, Piauí, Ceará, Rio Grande do Norte, Paraíba, Pernambuco, Alagoas and Bahia); the Midwest (the states of Mato Grosso, Mato Grosso do Sul and Goiás); and the Southeast (the states of São Paulo, Paraná and Minas Gerais). In all these states all the different production systems are found, from very small family farming units of <4 ha, small farming units of <100 ha, and large farming units of >1,000 ha. The larger cotton growers tend to use a higher level of technology; work health and safety monitoring; BMP (best management practices); IPM (insect pest management); and a better level of environmental monitoring.


Summary form only given. The time dependence of the MeV ion abundance can provide critical information on acceleration mechanisms in the dense plasma of focused discharges. Time resolved measurements of neutrons and hard X-rays are used to gauge the time evolution of ion population. The plasma focus (7 kJ; 17 kV) chamber was filled with O/sub 2/ (10%) and D/sub 2/ (90%) mixture. Time resolved measurements were done at different distances from the pinch (L) and at different angles (/spl theta/) from the electrode axis by NE102 (L=0.15 m; /spl theta/=0/spl deg/) and NE111 (L=3.8 m; /spl theta/=0/spl deg/ & 90/spl deg/) plastic scintillators. Time integrated absolute measurements of total yield of D(d,n)/sup 3/He and /sup 16/O(d,n)/sup 17/F nuclear reactions were used to establish population of low (E<0.5 MeV) and high (E/sub i/>2 MeV) energy ions. Measured neutron and hard X-ray signals (E/sub x//spl ges/100 keV) were unfolded to recover the real time resolved emission signals P/sub n/ & P/sub x/, respectively.


Purpose. To present the model of tectonic development of the Irtysh shear zone, based on recent uraniumlead dating for zircon. Methodology. The authors analyzed the results of studies of foreign and domestic scientists, conducted field research, sample preparation, carried out isotope studies using SHRIMP2 and LAICPMS technology; determined small elements by the fusion method using ICP. Findings. Based on more than ten uraniumlead dating for zircon using the local method and the given geological and struc tural data, model of the Irtysh shear zone tectonic development has been proposed Originality. A tectonic model has been developed and the age and structural relationships of the Irtysh shear zone with the KalbaNarym zone based on uraniumlead zircon dating have been established. Practical value. The article considers the structural and age relationships of the Irtysh crush zone which prove its formation along the deep Irtysh fault in the course of a long multistage tectogenesis.


The in situ molecular-probe FTIR spectroscopy was employed in the present workto study the adsorption of CO and SCN- on surfaces of dispersed Pt and Pd thin layers,which were deposited electrochemically on glassy carbon (denoted as Pt/GC and Pd/GC)uner voltanmmetric conditions. Abnormal IR features of adsorption of CO and SCN- andPt/GC and Pd/GC have been observed for the first time. In comparison with IR features ofadsorption of these molecules on smooth Pt and Pd electrodes, the abnormal IR featuresconsist of mainly the inversion of the direction of IR band and the enhancement of bandintensities. The enhancement factors were evaluated at 20 for linearly bonded CO on the Pt/GCsurface anal at 26 for bridge bonded CO on the Pd/GC surface. Nevertheless other spectralfeatures(the vibrational frequency, the Stark effects, etc. ) are nearly the same as thoseobserved on smooth Pt and Pd electrodes, and no significant difference in IR features presentedfor adsorption of solution species (CO2, SCN- ) on the dispersed surfaces. The surfaceroughness of these dispersed electrodes was measured relatively small (1.6 for Pt/GC and 1.2for Pd/GC). The present study discovered an interesting IR property of dispersed metallicthin layers, and suggested that the in situ iR spectra of larger signal to noise ration may beobtained by employing the specially prepared Pt/GC and Pd/GC electrodes.


According to image processing technology,this thesis brings forward an automatic detection and tracking algorithm of multiple underwater moving targets based on feature cost function.The moving targets are detected by interval frame symmetry difference method,and forecasted by the Kalman filter method.The center of mass,speed,size,perimeter,the ratio of length to width of the potential target are calculated.And then a cost-function based on these features is constructed for target tracking.It succeeds in detecting automatically and tracking multiple underwater moving targets.


In the last years, the tunnelling industry is increasingly faced with a demand for expertise in the design and installation of anchors to concrete. This is also made evident in construction with recent publications that are now the basis in anchor design, specification, and installation, such as the Code of practice for the selection and installation of post-installed anchors, the Eurocode 2 - Part 4 "Design of Fastenings for Use in Concrete", and various guidelines by owners of tunnels. These documents do not only witness the high level of sophistication needed nowadays but also the increased need of the industry for furthering the know-how and the regulatory framework on fastenings. At the same time, particular focus has been drawn in the last years to the long-term performance of fastenings. This paper aims
to summarise the experiences from recent research and design practice for fastenings in the past, and to highlight anticipated future developments in the engineering and technology of fixings for tunnel fit-outs design and maintenance.


Competition in the era of globalization of the international community was hit by devastating changes. This becomes very crucial because each company vying to dominate the market. Various ways done by companies that have good competitive positioning. The establishment of good competitive positioning cannot be separated from the leadership style that can create strategic vision and manage the company's operations are well that is strategic leadership. Strategic Leadership application of good leadership cannot be separated from the support of intellectual capital of the company. This study aims to examine the effect of the strategic leadership to competitive positioning through intellectual capital against non-manufacturing companies. The respondents were top-level management of various companies in Surabaya. The analysis technique used to process the data was Partial Least Square (PLS). The results showed that the strategic leadership affect the intellectual capital,  and the intellectual capital affect the competitive positioning where the intellectual capital was the intervening variable.


The dragon y topology is becoming a popular choice for build- ing high-radix, low-diameter networks with high-bandwidth links. Even with a powerful network, preliminary experi- ments on Edison at NERSC have shown that for communica- tion heavy applications, job interference and thus presumably job placement remains an important factor. In this paper, we explore the e ects of job placement, job sizes, parallel workloads and network con gurations on network through- put to better understand inter-job interference. We use a simulation tool called Damsel y to model the network be- havior of Edison and study the impact of various system parameters on network throughput. Parallel workloads based on ve representative communication patters are used and the simulation studies on up to 131,072 cores are aided by a new visualization of the dragon y network.


Abstract. A study of clarinet reeds demonstrates the capabilities of digital holography for identification and measurement of vibration modes, measurement of static displacement and creep, and measurement of shape profile. Three types of synthetic reeds were examined together with a number of cane reeds both wet and dry. It is shown that the synthetic reeds have fundamental vibration mode frequencies that are lower than those of natural cane reeds. The fundamental modes of cane reeds all lie above the range of notes played by the instrument whereas those of synthetic reeds do not. Examination of static displacements due to steady air flow showed creep effects due to inelasticity. Finally, projected fringes were used to measure the reed profile.


In this paper, we revisit the long-standing open problem asking the exact provable security of triple encryption in the ideal cipher model. For a blockcipher with key length κ and block size n, triple encryption is known to be provably secure up to 2 1 2 min{κ,n} queries, while the best attack requires 2κ+min{κ, n 2 } query complexity. So there has been a gap between the upper and lower bounds for the security of triple encryption. We close this gap by proving the security up to 2κ+min{κ, n 2 } query complexity. With the DES parameters, triple encryption is secure up to 2 queries, greater than the current bound of 2 and comparable to 2 for 2-XOR-cascade [10]. We also analyze the security of two-key triple encryption, where the first and the third keys are identical. We prove that two-key triple encryption is secure up to 2κ+min{κ, n 2 } blockcipher queries and 2min{κ, n 2 } construction queries. For the DES parameters, this result is interpreted as the security of two-key triple encryption up to 2 plaintext-ciphertext pairs and 2 blockcipher encryptions.


NiCrAlYSi coating with a thickness of 170~ 180 μm was deposi-ted on the surface of GH3030 Ni-based superalloy by arc ion plat-ing(AIP) in vacuum.The oxidation behavior at 700℃ and cor-rosion behavior in hot combustion gas at 760℃ of the coating were investigated respectively.Results show that Al2O3 and Cr2O3 oxidation layers are formed on the surface of the coating,which can enhance the oxidation resistance of GH3030 alloy at elevated temperature.Upon exposure to hot combustion gas at 760℃ for 100 h,the NiCrAlYSi coating was mainly composed of Ni3Al and a-Cr,and significantly improved low-temperature hot corrosion resistance of the Ni-based superalloy.


A method for providing local voice dialogue applications on mobile terminals (7) of vehicles (9) comprising the steps of: (A) generating local voice response applications through a server (2), wherein the speech dialog applications each having a formal description of a speech dialogue in a specific description language and speech models for individual dialog steps of the speech dialogue; (B) transmitting the generated local language dialogue application by digital broadcasting from a broadcast transmitter (4) to a radio receiver (10) of the respective in a local broadcast area of the broadcast transmitter (4) located mobile terminals (7) over a certain local radio receiver frequency (f); (C) each local radio receiving frequency (f) Internet addresses of local web pages are assigned from which the server (2) generates the local voice dialogue applications for transmission in the corresponding local coverage area automatically, and (D) the relevant language dialogue application includes a time stamp for the time of their production.