This study aimed to describe the temporal structure of judo combat for the different weight categories in men with visual impairments so that coaches can adapt traditional judo training methods to this specific population. Observational methodology was used in 184 combats (n = 92 male senior judokas with visual impairments). A T-Patterns study (THEME) and a descriptive and inferential statistical analysis were carried out. The results showed that most of the observed combats ended before regulation time was over (81%). The different weight categories must be taken into account in order to establish adequate training patterns for this population. Special attention must be paid to Work Sequence Time in Stand-up Judo (WSSQT) since this parameter showed significant differences (p = 0.001). The mean values obtained in the studied combats indicate that visual disability accounts for the shorter work sequences and longer pause sequences observed in this group of judokas. These results confirmed that the temporal structure of judo combat in male athletes with visual impairments is different from that of fully-sighted ones. Given all that, a different approach to training each group of judokas becomes necessary, since the temporal structure of the combat is different in each case.


The circumstances that determine the choice of a career form a fascinat ing subject for speculation in the realm of human psychology. Few generals have duplicated George S. Patton's almost neonatally developed ambition to become a soldier (my father appointed him to West Point), and I have en countered only one physician or surgeon who cannot recall the time when he did not expect to be a doctor. During long service on committees charged with the selection of medical students, I have interviewed hundreds of young people who had decided to study medicine. After a coupl e of years of this duty I concluded that little was to be gained by asking the trite and obvious question: "Why do you want to be a doctor?" Many, including not a few who went on to successful careers in scientific medicine, were unable to give any very definite answer. I learned to regard this as a better omen than a flowery profession of a desire to help mankind. When I put the same question to a number of senior clinical colleagues I usually got an answer which indi cated that some rather trivial incident had directed their attention to the idea of studying medicine. Thereafter some ill-defined inner urge sufficed to po tentiate the original slightly supraliminal stimulus. That is surely an effective form of motivation. Joseph Erlanger (5) has told us that the idea of medicine as an occupa tion came to him from an older sister "who, in my youth, had nicknamed me Doc because of my interest in lower forms of life." A noted clinical micro biologist told me that he went to medical school because of the impact of an incident related in a book for children he had read at the age of eight: the recovery of a child from a severe head injury without any specific treatment! Sometimes discouragement encountered in attempting another metier serves to lower the threshold for an excitatory suggestion that medicine may be a way out. Such was the case of Claude Bernard, whose literary activities dur ing his apprenticeship to an apothecary in Lyon caused his employer to re quest that the young man be restored to his parents. The story has been beau tifully told by Olmsted (7). Although disenchanted with the rolling of pills and preparing certain compounds-includ


Wedding Bellas is a digital photography and oral history project that explores a wish to belong to the European borderscape. The photographs are the stories of twelve women who found themselves at a time when they refused to leave. Many have been rejected – by partners, by landlords, by employers – and many have been refused leave to remain in the United Kingdom by the state. The women displayed resilience and resourcefulness in the face of these rejections, sometimes all happening at once, and the burden of those denials made them escape to fantasy. Some opted for equally stable, rooted and good-looking 'Queen's subjects' – a lamp post, a tree, a traffic sign; London landmarks. The artwork presents the brides as physically connected to their rooted British fellows. The images show desperation and illusion as with a true wedding ceremony. The paradox of this loss of reality, due to the pressures of life circumstances, is portrayed in the photographs, questioning if the situation the women are in is imaginary – a concept shared by both the audience and the person in the picture. With the nexus of text and image, the project troubles the perception of refugees and asylum seekers in the United Kingdom today and the role that digital technology plays in that process. It deals with the question of mediation of migrancy through the historic visual representation and mnemonic depictions in photographs that are challenged by the interventions of the migrants themselves in that process.


The present invention provides a furnace mix drum (3), which is configured to include a main body and accommodating the material (1) for the mixing, the lining system of the drum has an appropriate lining system, is the injected ceramic block which comprises a polyurethane liner.


Knowledge of the scatter characteristics of candidate infrared sensor dome materials is necessary for the evaluation of image quality and susceptibility to bright off-axis sources. For polycrystalline materials in particular, the scattering levels are high enough to warrant concern. To evaluate the effects of scatter on image quality, estimates of the window Point Spread Function (PSF), or its transform, the Optical Transfer Function (OTF) are required. Additionally, estimates of the material scatter cross-section per unit volume are essential for determining flare susceptibility. Experimental procedures and models in use at JHU/APL allow the determination of each. Measurement results are provided for samples of A1203 (ordinary ray), Y203, LaO3-doped Y203, MgAL2O4, and ALON. Applications of these results are illustrated for planar windows having arbitrary orientations with respect to the optical axis.


Here we propose a simple explanation why echoes from wormholes mimicking black holes may be so small that they cannot be observed. The essence of the effect is in the redistribution of the initial energy of gravitational wave among multiple universes, connected by a wormhole.


Objective To evaluate the relationship between pulse pressure(PP),pulse pressure index(PPI) and hyperuricemia(HUA) among middle-aged and aged residents in Chengdu.Methods Based on the level of PP [≤60 mm Hg(1 mm Hg=0.133 kPa),60 mm Hg] and PPI(≤0.450,0.450),We divided the 1 061 middle-aged or aged people into normal PP/PPI group and augmented PP/PPI group.All patients came from the survey for metabolic syndrome study in May 2007.We analyzed the distribution of serum uric acid(UA) and HUA,and analyzed the relationship between PP,PPI and HUA by using single-factor and logistic regression analysis.Results The index of UA in the augmented PP/PPI groups was higher than that in the normal groups with a significant difference(P=0.000).The prevalence of HUA in the augmented PP/PPI groups was statistically higher than that in the normal groups(P=0.026,0.027).Single-factor and logistic regression analysis showed that PP and PPI were both positively correlated to HUA.Conclusion The abnormalities of PP and PPI are closely related to metabolism disorder in Chengdu,and high level of PP or PPI is probably risk factors for HUA.


This analysis will briefly explain some of the reasons for and implications of the classification of debtors in insolvency law, and the difficulties in finding the appropriate classification system for small unincorporated businesses, particularly sole proprietorships. I will then consider the classification system in South African insolvency law, and compare it to those in a number of other jurisdictions. In conclusion, I will deal with the current developments in South African corporate and insolvency law and the extent to which these developments may improve the situation of small unincorporated businesses experiencing financial difficulties.


Simple Summary In the current study, we hypothesize that the In ovo concurrent injection of methionine (Met) and cysteine (Cys) may have positive effects on embryonic development, insulin-like growth factor-I (IGF-I) and toll-like receptor-4 (TLR4) gene expression, antioxidant status, biochemical profile, and jejunum histomorphometry of newly hatched broiler chicks exposed to heat stress during the incubation period. As indicated, the In ovo injection of Met and Cys resulted in increased hatch weight, higher levels of total antioxidant capacity, and glutathione activity in the serum and tissues. At the same time, a decrease in the level of heat shock protein-90 and an increase in TLR4 and IGF-I expression in the tissues was observed. In addition, the In ovo injection of Met and Cys improved jejunum histomorphometric parameters of newly hatched broiler chicks. Generally, the concurrent In ovo injection of Met and Cys improved broiler embryonic development, antioxidant status, TLR4, and IGF-I expression and jejunum histomorphometric parameters in newly hatched broiler chicks exposed to heat stress conditions during incubation. Abstract Sulfur amino acids are typically the first-limiting amino acids (AA) used in protein metabolism in poultry. Therefore, we hypothesized that their utilization in the pre-hatch period would affect embryonic development, IGF-I and TLR4 gene expression, antioxidant status, serum biochemical profile, and jejunum histomorphometry of newly hatched Ross broiler chicks incubated under heat stress conditions. A total of 150 fertile broiler eggs were subjected to heat stress (39.6 °C for 6 h/d) from d10 until d18 and injected at d 17.5 of incubation with methionine and cysteine (Met-Cys) at a dose of 5.90 mg l-methionine plus 3.40 mg l-cysteine. The effects of Met-Cys administration were examined and compared with the control (Non-injected group) and 0.75% NaCl injected group. The results showed that no significant differences among all groups in serum protein profiles (total protein, albumin, globulin, and albumin/globulin ratio) and creatine kinase were observed. The level of heat shock protein-90 was decreased with Met-Cys In ovo injection. The In ovo injection of Met-Cys also improved the values of total antioxidants capacity and glutathione in examined tissues. At the same time, an increase in fold change mRNA abundance of IGF-I and TLR4 was observed after Met-Cys injection in tested tissues. Finally, an increase of 29% in villus area was found after Met-Cys injection compared to the control group. In conclusion, the In ovo injection of Met-Cys resulted in improved embryonic development, IGF-I and TLR4 gene expression, antioxidant status and jejunum histomorphometry of newly hatched broiler chicks exposed to heat stress during incubation.


The crystal structure of [Fe(phen)2Cl2]NO3, recently published in the C2/c space group, has been redetermined. The revised structure is shown to belong to the lower symmetry space group Cc and to contain additional water and acetic acid solvent molecules involved in one-dimensional, hydrogen-bonded chains incorporating the nitrate counterion. Accordingly, crystals obtained by means of the reported procedure should be formulated as [Fe(phen)2Cl2]NO3·CH3COOH·H2O for proper use in further experiments.


The recently released Reflex scientific workflow environment supports the interactive execution of ESO VLT data reduction pipelines. Reflex is based upon the Kepler workflow engine, and provides components for organising the data, executing pipeline recipes based on the ESO Common Pipeline Library, invoking Python scripts, and constructing interaction loops. Reflex will greatly enhance the quick validation and reduction of the scientific data. In this paper we summarize the main features of Reflex, and demonstrate as an example its application to the reduction of echelle UVES data.


This study aims to determine (1) the development of land use, (2) growth in population and the development of rural infrastructure covering housing, transport, health, water supply, electricity, telecommunications in Desa Bandar Setia 2004-2009. This research is descriptive qualitative data collection techniques using observation and documentation. The population in this study are all Desa Bandar Setia region that includes the physical condition of the area, population, and infrastructure located at Desa Bandar Setia well as a sample. Data processing techniques performed through descriptive method qualitative comparative analysis of 2004-2009 Desa Bandar Setia systematically. The results showed that the development of land use for settlements grew 7 ha (1.94%), reduced wetland 6 ha (1.67%), dry land reduced by 2 ha (0.53%), highways incremented by 1 ha (0.28%); total population of 7,377 inhabitants experiencing growth or a growth rate of 11%; development of infrastructure for housing permanent and semi-permanent increase 849 units, housing non-permanent decreased 212 units, transport increased 772 units, health facilities especially clinic / dispensary increased 3 units, provision of safe water increased 827 units, customer electricity network increased 1,120 units (7.78%), and telecommunications increased 563 units.


We discuss the problems associated with changing individual correlation values in a valid correlation matrix and outline a solution for calculating upper and lower bounds within which correlations can be modified, such that the resulting correlation matrix is still valid. We illustrate two particular applications of our solution: Sensitivity analysis of portfolio risk to an individual correlation coefficient and randomization of correlation coefficients in particular blocks of correlation matrix.


Infield experiments on light chestnut soils of Mountain Shirvan, the effect of the dose and the ratio of organic and mineral fertilizers on nitrogen removal from aboveground biomass, grain quality, crop yield and economic efficiency in winter wheat crops were studied. The work was carried out in 2011–2014. During the work, standard methods for the determination of chemicals were used. As a result, the work is established. That high yield and net income were obtained in option N90P60K60.


Abstract The effect of transient supersaturations on the concentration of cloud condensation nuclei (CCN) in a conventional parallel-plate type thermal diffusion chamber is experimentally investigated by controlling the relative humidity of the sample and the temperature of the top and bottom plates individually. It is found that the error in CCN counts is quite significant around 90% relative humidity and might be dominant at cloud bases where the relative humidity approaches 100%. The error is a combined result of thermal and hydrodynamical transients. It is suggested that a chamber having a continuous and laminar inflow of the sample which has the steady-state temperature profile already existing in it is but suited for reliable CCN measurements. The calculations based on the theory of Saxena, Burford and Kassner help explain the obtained results which also support the earlier theoretical predictions of Fitzgerald. The results seem to disagree with recent experimental observations reported by Radke and...


Introduction: Bariatric surgery is considered the most effective obesity treatment. Obese patients have a high prevalence of eating disorders. Objectives:  Evaluate the occurrence of eating disorders and eating patterns in candidates for bariatric surgery and associate eating disorders with sociodemographic and clinical characteristics. Methods: A retrospective study was conducted using electronic charts of candidates for bariatric surgery. Data were collected on sex, age, marital status, schooling, occupation, non-communicable diseases, body mass index (BMI), eating disorders, and eating patterns. Results: Among the 281 patients evaluated, eating disorders were detected in 26.7%; 10.3% had binge eating disorder, 6.6% had bulimia nervosa, and 5.3% had the night-eating syndrome. The specific eating patterns were overeating (46.6%), binge eating during periods of stress (9.3%), eating sweets (4%), and snaking (1.3%). BMI ranged from 35.38 to 59.03 kg/m² (mean: 44.37 ± 5.89). All individuals (100%) had systemic arterial hypertension, and 23.3% had type 2 diabetes mellitus or dyslipidemia. Conclusions: The frequency of eating disorders was low in the sample studied, the most common of which was binge eating disorder. Non-communicable diseases were associated with eating disorders. Among the eating patterns observed, the most frequent was overeating.


The authors report no conflicts of interest for the published content. Address correspondence to: Rahul N. Doshi, MD, FACC, FHRS, Division of Cardiology, Keck USC School of Medicine, 1510 San Pablo Street, Suite 322, Los Angeles, CA 90033, USA. Email: firstname.lastname@example.com. Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice. The symptoms often associated with AF, such as dyspnea, fatigue, and palpitations, may be associated with other cardiac conditions such as heart failure, which may make recognition of the condition in certain patients more difficult. This can, in turn, cause a delay in the performance of a timely evaluation and treatment initiation. There are multiple identifiable risk factors for AF including hypertension, obesity, smoking, diabetes, sleep apnea, and alcohol intake. An enduring question is how and when is it best to address these risk factors. To date, there is a scarcity of evidence-based studies demonstrating preventive interventions that reduce or prevent the occurrence of AF.


Small-island developing states (SIDS) enhance their competitiveness by advertising development initiatives that promote and encourage direct foreign inward investment opportunities in major markets. Failure to make use of information communication technologies (ICTs) can undermine national development initiatives with transformative potential. Based on this logic, some Caribbean governments have followed international best practices of businesses and have moved towards the creation of websites and the establishment of portals or gateway sites on the World Wide Web to announce their presence.  One of the practical implications of such initiatives is based on the assumption that once websites are built, persons will come. Although for many, the development of a website appears to be an innocuous endeavour this mistaken perception in most cases has led to several sites being designed and commissioned as technical projects mostly employing techno-centric approaches. These policies often ignore the accompanying important socio-technical institutional considerations, such as the importance of timely and accurate information to potential business clients or prospective developers, language capabilities, and a range of standards, guidelines, rules and legislative changes. The central thesis of this conceptual paper is that if member states of the region properly conceptualise and design websites and portals they can be used to achieve strategic national and international development objectives of egovernance in its broadest meaning. The arguments are intended to stimulate thought among policy makers and the private sector alike in the Caribbean with a view to bringing about change that will promote sustainable development.


There appear some problems after inserting AutoCAD into Word.Seven kinds of data switching methods between AutoCAD and Word are compared here through the detailed narration and explanation of operating process.Two methods are recommended such as BetterWMF and copying the words of Word into AutoCAD,which are simple,fast and perfect.Further more,the problems and skills in using these two methods are also discussed in this paper.


The present invention provides a separator which is characterized in that it comprises an exposed layer of fine skeleton of the polyolefin-based resin which is the coating layer and the polyolefin-based resin, which is covered with the glass layer is exposed. In addition, the present invention includes a positive electrode and a negative electrode and an electrolyte and a separator, and the separator, providing a cell, it characterized in that the fine skeleton of the polyolefin-based resin will be provided with a coating layer that is coated with a glass layer, a further polyolefin-based resin, polysilazane viscous containing only a residual compound (粘 凋; viscous; stepped) liquid body, or polysilazane precursor comprises a liquid mixture of the upper and polycarboxylic view la remaining compounds of viscosity containing only a residual compound have installed after, the precursor provided on the polyolefin-based resin bath; it is immersed in (水浴 water bath), the manufacturing method of including the step of covering the fine skeleton of the polyolefin-based resin, by drying the glass layer separator It provides. The battery can, the positive electrode, the positive electrode current collector, the positive electrode mix layer, a negative electrode, the negative electrode collector, the negative electrode mix layer, a separator, a positive electrode lead, the negative electrode lead, the winding electrode body (spiral electrode body), the battery element.


Green marketing has become a phenomenon to protect our earth from environmental destruction. As resulted, many companies from various industries have implemented the green revolution and fulfilled market demands by creating green products. The concern toward environment makes people change their behaviors toward the products they consume in their daily life. Hence, this paper explored the customer behavior towards green products, green customer satisfaction and the impact of green products on customer satisfaction and environmental safety. The data collection techniques used are observation, questionnaire and literature study. This study used Path Analysis for data analysis techniques with three tests, classical assumption test, regression analysis, and correlation analysis. The study result showed Green Product significantly affected Environmental Safety by 59.9% and to Customer Satisfaction by 39.4%. Meanwhile, Environmental Safety did not significantly affect the Customer Satisfaction, which was only 19.2%. The effects of Green Product on Customer Satisfaction through Environmental Friendly simultaneously were 28.2%, the remaining influenced by other factors which cannot be explained in this study.


The integration of these multiple perspectives, rooted in relevant theory, results in a study with implications for other cultural settings. Hornberger's carefully document-ed work is of considerable significance for researchers, educators, and policymakers addressing issues related to bilingual education, language planning, and language maintenance.


his belief that the philosophical life is exclusive of other pursuits in life, and his focus on ethics and neglect of physics and logic. The Companion is a wide-ranging, stimulating and affordable collection that will be enjoyed by specialists and used in the classroom. Part 2, 'Socrates After Antiquity', makes the volume distinctive amongst similar handbooks and companions, giving it the historical scope of M. Trapp's two-volume collection on Socrates (2007). All Greek is transliterated and there is an extensive index, but no index locorum. Bibliographies, a few of them annotated, are provided at the end of almost every essay.


Nesidioblastosis is a well‐recognized cause of persistent hypoglycaemia in neonates. We describe the case of a 24‐year‐old woman who presented with hyperinsulinaemic hypoglycaemia in whom an insulinoma could not be identified at operation which resulted in her undergoing a subtotal distal pancreatectomy. Histological examination revealed the presence of nesidioblastosis. The finding of nesidioblastosis in adults has been reported previously, albeit rarely. We report the use of in situ hybridization to characterize the patterns of insulin and proglucagon gene expression in the resected pancreas. Insulin expression was observed in both the islets and also the isolated nesidioblasts. The α‐cells of the islets had lost their usual peripheral distribution suggesting that not only is insulin gene expression dysregulated but that the islets are structurally abnormal.


Outdoor vacuum circuit breaker are the most commonly used switchgear in the Medium High Voltage(MHV) segment particularly in the 11 kV and 33 kV distribution grids. As these breakers are used in outdoor switchyards they are exposed to varied weather conditions. A study was undertaken to ascertain the performance of outdoor Vacuum Circuit Breaker (VCB) under simulated low and high ambient conditions which are presented in this paper. The results of this study have been analyzed to understand the performance of the MHV Outdoor VCBs under various low and high ambient conditions. Important conclusions derived from the study have been discussed in the paper.


The invention relates to a telephony system assisted by operators designed for users put off by the complex telephone services and terminals. The user (11,12,13), with a simplified telephone terminal, fixed or mobile, without screen or keyboard, answers or initiates a call by simply manipulating a handset, a button or a shutter. When called, it is directly put in touch with an operator (14). This operator is supported by a database (15) which gives the references, preferences and instructions of the caller, in particular phonebook and useful medical information in an emergency. Optionally, the terminal transmits the location of the caller. The operator can therefore effectively meet various desired and subscribed by calling services. The database is updated by subscribers, operators and authorized third parties, internet connection, email or phone. The operator works from a distance, for example at home, and signals its availability to the network which then needed referrals if possible to their usual or preferred operators.


Emerging areas of nanotechnology hold the promise of overcoming the limitations of existing technology for intracellular manipulation. These new developments include the creation of nanocomposites that can be introduced into the cells, targeted to specific subcellular sites, and subsequently used as platforms for initiation of intracellular processes dependent on or aided by locally high concentrations of specific molecules delivered as components of the nanocomposites. Nanocomposites that combine functional properties of biomolecules with the functional properties of inorganic components could provide new tools for biology, medicine, chemistry and material sciences. Here we describe how we introduced TiO{sub 2}-DNA nanocomposites into cells, and localized titanium in the cells by mapping the Ti K{alpha} X-ray fluorescence induced at the 2-ID-E microprobe of the SRI-CAT at the Advanced Photon Source at Argonne National Laboratory.


IN certain experiments on iron metabolism, involving the iron-containing protein of egg-yolk, lecitho-vitellin, we planned to make a large number of iron estimations. To conserve our small supply of protein, the preparation of which had involved considerable time and labour, we desired to cut down the size of the sample analysed to the smallest amount on which an accurate iron determination could be made. The author and colleagues [1930] had already found that the iron content of egg-yolk protein could be accurately determined by the method of Kennedy [1927]. The samples then analysed contained about 0 05 mg. iron, an amount somewhat greater than that which we now wished to estimate. The results of a critical study of Kennedy's procedure as the basis of a micro-colorimetric method are recorded in the first part of this paper. The second part is concerned with the determination of small amounts of iron in biological materials by potentiometric titration with titanous sulphate.


Study on the crystallization process of amorphous (Fe 0.99 ,Mo 0.01 ) 78 Si 9 B 13 (FMSB) alloy with and without solid state reaction at their surfaces were carried out under pressures from 3 to 5 GPa at a temperature range of 510 to 660℃ . When the amorphous FMSB alloy with the reaction was annealed at the temperature range, it is transformed into nanocrystalline α - Fe( Al) at 4 GPa and α - Fe (Mo, Si), (Fe, Mo) 3 B or Fe 2 B at other pressures, which were as same as the crystallization products of the amorphous alloy without the reaction at the same pressures. The crystallization mechanism of the amorphous alloy with the reaction was suggested on the basis of therrnodynamic theory and a simple solid model.


Objective To reveal the worldwide research status and hot topics of sleep apnea syndrome(SAS).Methods Articles were searched from Web of Science(SCI),Essential Science Indicator(2000 to 2010) database using sleep apnea syndrome or apnea as keywords..Retrieved documents were analyzed using the database with its own statistical functions and histcite software(version 8.12.16).Results Since 1992 the international scientific papers on the SAS study showed a gradual upward trend.The United States is a world leader in this field.Recent research has focused on vascular endothelial barrier function and repair,oxidative stress,inflammation,cognitive function,special populations such as the elderly or children patients with SAS.Conclusion Clinical researchers have paid more attention to SAS than before,but there are still many important issues unresolved.


Feature matching is a core step in multi-source remote sensing image registration approaches based on feature. However, for existing methods, whether traditional classical SIFT algorithm or deep learning-based methods, they essentially rely on generating descriptors from local regions of feature points, which can lead to low matching success rates due to various challenges, including gray-scale changes, content changes, local similarity, and occlusions between images. Inspired by the human approach of finding rough corresponding regions globally and then carefully comparing local regions, and the excellent global attention property of transformers, the proposed feature matching network adopts a coarse-to-fine matching strategy that utilizes both global and local information between images to predict corresponding feature points. Importantly, the network has great flexibility of matching corresponding points for any feature points and can be effectively trained without strong supervised signals of corresponding feature points and only require the true geometric transformation between images. The qualitative experiment illustrate the effectiveness of the proposed network by matching feature points extracted by SIFT or sampled uniformly. In the quantitative experiments, we used feature points extracted by SIFT, SuperPoint, and LoFTR as the keypoints to be matched. We then calculated the mean match success ratio (MSR) and mean reprojection error (MRE) of each method at different thresholds in the test dataset. Additionally, boxplot graphs were plotted to visualize the distributions. By comparing the MSR and MRE values as well as their distributions with other methods, we can conclude that the proposed method consistently outperforms the comparison methods in terms of MSR at different thresholds. Moreover, the MSR of the proposed method remains within a reasonable range compared to the MRE of other methods.


The selective flocculation process is reviewed and the important mineral separations which have been achieved are listed. A report is then made of the results of a laboratory study made on the physical variables in a stirred tank affecting the separation of hematite from silica by selective adsorption by the hematite of long chain anionic polyacrylamide. Conclusions reached were that in general greater charge on the polymer and high molecular weight improve separation. High flocculant concentrations are unnecessary and about 1 ppm is sufficient. Low slurry concentrations and short agitation times are important, while there is an optimum impeller speed in the stirred tank.


We present one component of a foundation for mobile, handheld device-supported collaborative learning (mCSCL), a design framework. Our design framework proposes that mediation can occur in two complementary layers, social (e.g. rules and roles) and technological. Further we suggest that for mCSCL, the technological layer has two components, representational mediation and networked mediation. A particular design challenge is achieving an effective allocation of supporting structure to each layer as well as simple, transparent flow between them.


Didactic demonstrator solar hydrogen cycle. Didactic demonstrator solar hydrogen cycle, is to show the usefulness of the electrolyzer system PEM - fuel cell generation and supply of hydrogen and oxygen from photovoltaic panels, and its transformation into electrical energy. The demonstrator is designed to show a clear and simple processes taking place in the system manner. The demonstrator consists of five main parts: 1. Photovoltaic panels, PEM electrolyzer 2., 3. Fuel Cell, 4. Implementation 5. Digital readouts voltage and current. Photovoltaic panels on the roof of a mock capture sunlight and convert it into direct current. This current is used to produce water electrolysis. The hydrogen and oxygen generated are used in the fuel cell to generate electricity can operate a specific application, fan and / or lighting. In processes in which energy is generated and consumed they are placed digital displays voltage and current.


The crosshole seismic testing method has a great potential. In the course of observations a dense network of seismic rays is obtained that travel through the region of interest. As a result, the method provides enhanced approaching the object of research. There are two ways of obtaining crosshole sections: migration and crosswell CRP. Basically, the dominated frequency of crosswell seismic data is higher than the dominated frequency of surface seismic data by several times. The imaging derived from the data can indicate the geological structure between wells clearly and can be used for detailing reservoir characterization and residual oil potential seeking. The source and receiver in such a way are close to the interface formation, so that the wavefield of crosshole seismic testing can receive more information and much more complex than of the surface seismics or VSP.


Introduction Embodying Ageing Debates in the Sociology of the Body Social Fields as Spaces of Disruption Capturing Ageing Embodiment Disrupted Biographies Managing Ageing Mapping an Embodied Sociology of Ageing Conclusion Index


This study is to investigate the influence of impurity on the liquid insulation of aging transformer oil caused by the material properties of the test methods of physical, chemical properties, and electrical properties. Testing for impurity analysis of the oil is to increase the pure water content (ppm) at a temperature of 30C, then measure the breakdown voltage and surface tension. The test for oxidation stability analysis that is badder test duration 10 days at 100C, then measure the surface tension, acidity and tangent delta. The results obtained showed that the increase in operating temperature above 60 C will cause decomposition of the physical properties and chemical properties so that the performance of aging oil and grease must be purified like (flushing, rekuperasi) to reduce the impurity. Good maintenance and supervision will be very useful to maintain quality isolation transformer oil and transformer winding to reduce the risk of damage.


Contact surfaces between non-planar elastomers widely present in the industrial and biomedical fields, such as corrugated mats and biological fillers. Probing out the mechanical instability of these contact surfaces could greatly contribute to the efficiency, safety and durability of the related structures. In this paper, we numerically studied the contact instability of non-planar elastomeric surfaces with typical projections (i.e., circular and triangle projections) by proposing an instability criterion and using the finite element method. Moreover, we studied the effects of several key factors (e.g., the geometrical parameters and the friction coefficients of the surfaces) on the critical force of the mechanical instability. It is found that with comparable geometric sizes, the surface with circular projections is more effective to enhance the contact stability than that with triangle projections. A larger slope and curvature radius result in weaker stability while a larger friction coefficient plays a positive role for the stability. However, with increasing friction coefficient, the maximum force presents smaller and smaller changes and further improvement of contact stability mainly depends on the changes of the number of projections. These investigations may improve the understanding of the mechanical instability of non-planar elastomeric surfaces and contribute to achieve better designs of related structures.


Preface Focal Degeneration of Aged or Injured Myoepithelial Cells and Resultant Auto-Immunoreactions Trigger Genetic Instability and Breast Cancer Invasion Chromosomal Instability and Cancer Spontaneous and Induced Chromosomal Instability in Patients with Carcinoma of Cervix Uteri Tumours: Their Complex Morphologies and Genetic Instabilities Genomic Instability of the APC Gene Found in Glioblastoma Radiation Hormesis and the Control of Genomic Instability "Delayed Division Delay" Revealed by Time-lapse Photographic Study: A New Endpoint of Radiation-induced Genomic Instability How a Cell Defends Itself Against Genomic Instability Caused by Chromium Genotoxic Stress, S Phase Checkpoint and Apoptosis Index.


Dr. Aaron Jacob Marcus, Professor of Medicine at Weill Cornell Medical College and distinguished physician-scientist in hematology and vascular biology, passed away on May 6, 2015 (Figure (Figure11).


The aim of this is to study fixed point theorems in bν(s)-metric spaces under the Pata-type conditions. As consequences, we establish common fixed point results of Pata-type for two maps in bν(s)- metric spaces.


Gaochang ancient city,as a pivot for political,economic,cultural and religious exchange between the ancient China and the West,occupies an important position in history.But after more than a thousand years of wind and rain erosions,and the destructions of wars and religious conflicts,the protection for the ancient city is not ideal,and there exist some serious problems in structure stability.The root causes of the city's disease are analyzed here,as well as the internal and external caused of the diseases.The measures and existing problems in protection for the earth ruin at present are expounded,and the focus and direction of protection for the ruin in future are put forward,in order to provide some references for its protection.


technology and target group Various cardiac disorders, eg, myocardial infarction and heart valve disorders, may leave the heart too weak to pump the volume of blood needed by the body in a given situation. The resulting condition is called heart failure. Heart failure usually develops gradually, depending on the severity of the underlying cardiac disease. Normally, the pumping action of the right and left ventricles is well coordinated. In heart failure, the form and function of the heart can change and cause dyssynchrony, ie, deficient coordination of the contractions of the ventricles. Implantation of a biventricular pacemaker, ie, cardiac resynchronization therapy (CRT), is a new method aimed at synchronizing the action of the heart, thereby enhancing its ability to pump. Pacemaker stimulation of the right atrium and/or right ventricle is a well-established method for treating a slow pulse rate (bradycardia). In CRT, an additional electrode is placed above the left ventricle. Although pharmacotherapy has a satisfactory effect in many heart failure patients with dyssynchrony, some patients are not adequately helped by this approach, or have difficulty tolerating adequately high doses of the medication. In Sweden, the potential target group for CRT is estimated at 200 to 300 individuals per million inhabitants and year, ie, approximately 2200 patients.


One of the most successful approaches in the synthesis of inhibitors of t he g lycosidases i s t he s ubstitution of t he e ndocyclic ox ygen i n monosaccharides by a nitrogen atom to get iminosugars. Given that many diseases h ave t heir o rigin i n t he malfunctioning of t hese e nzymes, t his glycomimetics bear s trong p otential a s dr ug c andidates. A t th eir p rotonated state, iminosugars are s upposed to mimic the g lycosyloxacarbenium cat ion, a common intermediate in the enzymatic glycoside hydrolysis of both αand βglycosides. Similarly to this species, most of iminosugars lack an anomeric substituent a t t he pseudoanomeric carbon and behave as broad range g lycosidase inhibitors: they show configurational selectivity but not anomeric selectivity nor selectivity among isoenzymes. Fifteen years ago we conceived that the substitution of t he s p endocyclic n itrogen at om i n cl assical i minosugars b y a s p pseudoamide-type nitrogen should result in a very efficient overlapping of the orbital hosting the N-lone-pair with the antibonding σ* orbital of the contiguous C―O bond, increasing the anomeric effect. This orbital interaction leads to a very high stabilization of axially oriented pseudoanomeric substituents, resulting in compounds with configurational and conformational integrity even in polar solvents. We called this new type of glycomimetics sp-iminosugars. Most interestingly, th eir s ynthesis is compatible with molecular d iversity-oriented approaches, al lowing s tructural modifications at the heterocyclic co re, the hydroxylation profile and the nature and location of exocyclic substituents with a relatively lo w s ynthetic c ost. V ery s elective glycosidase l igands b ecame t hus accessible. By taken advantage of the information obtained from X-ray data of sp-iminosugar:glycosidase complexes, compounds capable of inducing the correct folding of lysosomal storage disorders (LSDs)-associated glycosidase mutants (pharmacological ch amperones) h ave b een d esigned. D ifferent s trategies for t he p reparation of t hese p harmacological ch aperones f or t he t reatment o f Gaucher disease, GM1 gangliosidosis and Fabry disease will be presented. 1. Jiménez Blanco, J. L.; Díaz Pérez, V. M.; Ortiz Mellet, C.; Fuentes, J.; García Fernández, J. M. Chem. Commun. 1997, 1969-1970. 2. Takai, T.; Higaki, K .; Aguilar-Moncayo, M .; Mena-Barragán, T. ; Hirano, Y. ; Yura, K .; Yu, L. ; Ninomiya, H.; García-Moreno, M. I. ; Sakakibara, Y.; Ohno, K.; Nanba, E.; Ortiz Mellet, C.; García Fernández, J. M.; Suzuki, Y. Mol. Ther. 2013, 21, 526-532. Proceedings IWBBIO 2014. Granada 7-9 April, 2014 389


This chapter examines support for the compellence theory in three cases: the Malayan Emergency, the Greek Civil War, and the Philippines' campaign against the Huk insurgency. In the British campaign in Malaya, 1948–1957, the colonial government defeated a small, isolated Communist insurgency that failed to gain political traction even within the population of impoverished ethnic Chinese rubber plantation workers that it targeted as its often-unwilling base of support. In Greece in 1947–1949, the United States backed the repressive, fragile post-World War II Greek government and built its military capacity sufficiently to defeat the Communist and nationalist insurgents. In the Philippines in 1946–1954, the United States backed the Philippine government as a bulwark against Communist expansion in Asia, pressing for major governance reforms while building Philippine security forces. In all three cases, elite accommodation played a significant role in the counterinsurgent's ability to defeat the insurgency militarily, with the type of elite involved varying by case; uses of force included forcefully controlling civilians; and uses of force broke the insurgency before reforms were implemented, if they were implemented at all, as the compellence theory predicts.


Black people may view the January 6th, 2021, attack on the U.S. Capitol as the latest development in a long series of threats that white supremacy poses to their status in the U.S., whereas white people may apply a colorblind perspective. Thus, Black people were hypothesized to support prosecuting insurrectionists at higher rates than white people because they want the federal government to protect Black people's status. Results from a nationally representative dataset revealed that while a majority of both Black and white participants considered it very important for federal law enforcement agencies to find and prosecute those who broke into the Capitol, the odds of Black participants endorsing this view were 72% greater than the odds for white people.


The paper analyzes the reasons for the financial, legal and supervisory reasons that led the National Government to incorporate custodian in to the regulations of our
country and to integrate it into the management model of collective investment funds, and to analyze if the Assimilated the role prepared for this class of specialized
operators in the models of international regulation, were necessary under our scheme of operation, as well as to evidence if this figure was really necessary in our legislation. The foregoing, in order to know if the fundamentals in which the standard was configured, conform to the characteristics and conditions of the domestic market, or instead its implementation has not yet brought substantial benefits to the structure of this class of investment structures.


As Infrared LED scene projector technology has matured, so have the techniques used to enhance Non-Uniformity Correction. This paper will detail the data collection and system improvements made for IRLED system NUC tables.


The phenomenon of a changing society is taking place regardless of its size, state of
development or political philosophy. To this end, the paper has examined the origin and
causes of Information Society and described in details the characteristics of Information
Societies bygrouping the,m intq e.c;qn_omical,politica(and t~chnologica/ resources. It also
gives an overview of WSiS, "World Summit on the Information Society" and how the
summit has placed "Information" over "Communication" in having primary importance.
The paper concluded that WSIS recommended ICTs for National and International
development and hence there is need for all involved to develop the "Information
Society"


The invention provides an electrochemistry electrolytic cell for deep sea simulation environment tests. The electrochemistry electrolytic cell comprises an autoclave and an electrode frame in the autoclave. The autoclave is used as an electrolytic cell body. The electrode frame comprises a substrate. At least two working electrode through holes are preformed in the substrate and used for placement of working electrodes. A counter electrode is installed at the position right opposite to each working electrode, wherein the counter electrode is manufactured to be of a Pt net plate structure, a border is arranged on the periphery of the Pt net plate structure, and the border and the substrate are connected through a side plate. Slots are preformed in the middle of the substrate and used for installation of reference electrodes. Each working electrode, the corresponding reference electrode and the counter electrode form a three-electrode system. The electrodes are fixed to the electrode frame, the distance between the electrodes is kept unchanged, and therefore test repeatability and accuracy can be improved; the multiple electrodes form the high-throughput integrated three-electrode systems, simultaneous tests of the multiple electrodes can be achieved through one-time sealing and pressing, and a foundation is laid for rapidly and accurately obtaining corrosion data of metal materials at the high pressure environment.


An evaluation of the performance of the Matched-Pulse approach and the standard Time-Domain Reflectometry is presented. The effect of the network topology on their effectiveness is studied, first through physical interpretation, then by means of a mathematical analysis. All the discussed ideas are finally illustrated through simulation results.


This paper reports the results of fuel cell performance tests detailing the effects of Ni/Al layered double hydroxide (Ni-LDH) on the performance of alkaline direct methanol fuel cells (DMFCs). It is desirable to enhance the maximum rate of methanol consumption at a fuel cell's anode so that expensive bimetallic catalysts (such as Pt-Ru) would not be as essential to remedy the well-known sluggish kinetics and Pt catalyst deactivation tendencies of DMFCs. The test cells were constructed using partially hydrolyzed polyvinyl alcohol film membranes impregnated with a 10 M potassium hydroxide electrolyte. The cells were tested at a constant temperature of 40°C, and the effect of the addition of Ni-LDH to the membrane surface was studied by comparison of fuel cell polarization and power production curves of cells with Pt or Pt-Ru anodes paired with Pt cathodes. The benefits of Ni-LDH addition to DMFCs are clearly shown vis-a-vis the extended operating current densities and associated increases in power density for each catalyst type. The enhancement effect of Ni-LDH appears largely as enhancement of cell mass transport. Cells constructed with Pt anodes and membrane surfaces modified by Ni-LDH perform very nearly as well as Ni-LDH-free cells using bimetallic Pt-Ru anodes.


The article deals with an urgent problem in the methodology and organization of rehabilitation for patients with disorders in the locomotor system. The following aspects are discussed: improvement of the system of the patient rehabilitation on the basis of modern requirements of the legislature in action for rehabilitation; registration, licensing and certification of the existing rehabilitation centres; development of special programmes for rehabilitation. It is suggested to create, together with the Ministry of Labour and Social Policy of Ukraine, a coordination council at the Ministry of Health of Ukraine aimed at improvement of rehabilitation measures and provision of patients with technical means for their rehabilitation.


Saprophytic actinomycetes associated to the rhizosphere and rhizoplane of Discaria trinervis. A total number of 122 strains of actinomycetes were isolated from both rhizosphere and rhizoplane of the plant Discaria trinervis (Hook et Arn.) Reiche. By employing morphological criteria, the strains could be arranged into six genera: Streptomyces (54 strains), Actinoplanes (27), Micromonospora (20), Actinomadura (7), Pilimelia (4), and Streptosporangium (1), along with a category of nocardioform organisms (9). The actinomycetes population varied in number and composition according to the two different sources. Most of the strains (62.3%) were isolated from the rhizosphere, predominantly belonging to Streptomyces, Actinoplanes, Pilimelia, and nocardioforms. The remaining 37.7% derived from the rhizoplane, belonging to Streptomyces, Micomonospora, Actinomadura, and Streptosporangium. Strains of the genus Streptomyces were distributed in equal numbers in both habitats. All isolates were examined concerning their ability to degrade various biopolymers. Only 14 strains were recorded without any effect to degrade plant material. The rest of the strains could be estimated as active, in extreme cases being able to decompose up to five different substrates. A total of 68% of strains showed enzymatic activity to degrade starch, 65.6% pectin, 59% cellulose, 28.7% hemicellulose, 3.3% keratin, and 15.6% had strong affinities to use lignin as a preferable substrate. (Keywords: saprophytic actinomycetes, enzymatic activity, rhizosphere, rhizoplane)


Membrane proteins (MPs) play essential roles in determining the interactions of biological systems with their surroundings, and their reconstitution determines the application in a variety of areas. Artificial polymers are pursued in MP reconstitution for fabricating bio-hybrid materials due to their adjustable properties. In this work, a cationic amphiphilic copolymer was synthesized by RAFT polymerization of dimethylaminoethyl acrylate (DMAEA) and methylacrylate, followed by quaternization of the PDMAEA segments. The copolymer could self-assemble in water displaying a sphere morphology. As an example, MP bacteriorhodopsin could insert in the assembled micelles of the copolymer spontaneously when incubated together, which showed an affinity towards the surface of poly(ethylene terephthalate) film. This work may provide a facile strategy to prepare bio-hybrid materials for promising applications of membrane proteins.


In this paper, an optical design for a hollow planar waveguide spectrometer with Czerny-Turner is proposed. To decrease the propagation loss of the spectrometer, the design strategy of designing the tangential plane and the sagittal plane separately is proposed, corresponding to resolution and energy, respectively. The Czerny–Turner optical path is designed on the tangential plane, and the sagittal design theory and method are analyzed in detail. The ray tracing results show that the resolution of the spectrometer is better than 4 nm on the tangential plane, while on the sagittal plane, the detector receives the highest energy when the detector pixel height matches the distance between the two mirrors.


We propose a verification flow which aims at functional verification of embedded systems. We assume that the system is formally specified in a modeling language and implemented in a high-level programming language. The verification flow proceeds in two stages: first, we check for behavioral properties which indicate bad states at the level of the specification. Second, we prove that the individual components of the system conform to their specification. The first stage allows for the detection of design flaws in the system without considering implementation details, whereas the second stage refines the verification task allowing for the detection of functional bugs in the implementation. In both stages, the description of the verification task is automatically generated from the modeling language and the implementation language, respectively.


The objective of this paper is the computational and experimental study of the fracture behavior of spruce wood under quasi-static loading conditions during a three-point bending test. The experimental tests were performed on the electronic testing machine Zwick Z100 (Zwick-Roell GmbH & Co. KG, Ulm, Germany) with displacement control, according to the standard International Standard Organisation (ISO) 13061-4: 2014. The specimens were made of Norway spruce (Picea abies) wood, with dimensions of 25 mm × 25 mm in cross-section and 549 mm in length. Six tests were performed for each orientation (radial and tangential) of the wood fibres. Based on the experimental results, the computational model was created and validated by considering the mechanical responses in two different directions due to the orientation of the wood fibres. An orthotropic material model with damage evolution was selected as the computational model. The computational model was validated using the inverse procedure for the determination of the constitutive material parameters, including the damage parameters of three-point bending test specimens. A finite element method (FEM) in the framework of program package ABAQUS was used for the computational simulation, while the open code Optimax was used for the optimization procedure. Comparison between the experimental and computational force vs. the displacement response showed a very good correlation in the results for the spruce wood specimens under three-point bending tests, with Pearson′s correlation coefficient of r = 0.994 for the tangential and r = 0.988 for the radial orientation. Therefore, validation of the proposed computational model was confirmed, and can be used further in numerical simulations of the fatigue behavior of wood specimens.


The Australian grasswrens (Amytornis) comprise a genus of cryptically plumaged species inhabiting the arid regions of southern, western, central, and northern Australia. Isolated, fragmented populations characterise the distributional pattern of several species, whereas others appear to show ecophenotypic clinal variation in plumage patterns. These features have made the species-level taxonomy of the genus a matter of ongoing debate. We undertook qualitative considerations of morphological, biogeographical and ecological features in combination with quantitative DNA distance measures from published studies, to provide a comprehensive species level revision of Amytornis. In addition to the ten species recognised by Schodde and Mason (1999) (housei, textilis, goyderi, purnelli, ballarae, merrotsyi, woodwardi, dorotheae, striatus, barbatus), we also recognise as species the following: modestus, rowleyi, oweni and whitei. These fourteen species are placed into four subgenera: Amytornis, Magnamytis, Maluropsis...


Recent advances in nanotechnology in biomedicine have spurred the development of " smart nanodevices " ― integrated drug vehicles capable of ( i ) sensing targets inside the body and adapting their function based on these targets, ( ii ) modulating their properties and functions in response to internal or external stimuli, and ( iii ) operating at the target site. To date, we have studied polymeric micelles made by self-assembly of engineered block copolymers. The critical features of polymeric micelles, including the particle size, stability, and drug-loading and drug-releasing properties, can be modulated by engineering the constituent block copolymers. Several micellar formulations of antitumor drugs have been intensively studied in preclinical and clinical trials, and their utility has been demonstrated. Recently, we developed smart polymeric micelles with multiple functions. Introducing targetable ligands such as peptides and antibody fragments the surface of polymeric micelles enabled targeting of intractable cancers such as glioblastoma. The chemical structures of the micellar core-forming segments were optimized and the environment-sensitive properties were integrated to construct nanoscale delivery systems for nucleic acid medicines. imaging functionality into the nanodevices precise monitoring drug distribution and early feedback response to the helpful for customizing treatment protocols and thereby achieving safe and successful chemotherapy. In addition, we have studied combined nanodevice and medical device systems for super minimally invasive surgery. In my presentation, I will discuss recent achievements in the study of smart polymeric micelles for cancer diagnosis and therapy. Crest-Derived Cells Maxillofacial a useful cell source for bone regeneration therapy. bleaching treatment, a significant difference was detected between 10 % sodium polyphosphate and 10 % sodium polyphosphate + 10 % carbamide peroxide, 10 % carbamide peroxide and Nite White Excel. After five occasions of immersion in coffee solution, a significant difference was detected between 10 % sodium polyphosphate and artificial saliva. Scanning electron microscopy revealed that polyphosphate may have imparted acid-resisting properties on the specimens. Polyphosphate appears to impart stain-inhibiting and acid-resisting properties. peak amplitude of nerve activity increased in all four nerves ( CN : 140 % (cid:156) 8.7 % of control, n = 5 ; SLN : 111.2 % (cid:156) 3.15 % of control, n = 5 ; HN : 142 % (cid:156) 15 % of control, n = 5 ; PN : 127 % (cid:156) 8.8 % of control, n = 5 ) . Moreover, the hypercapnic acidosis advanced the onset of respiratory activity in the CN, SLN, and HN, with the reference being onset of respiratory activity in the PN. These results suggest that hypercapnic acidosis affects the pattern of movement of the muscles that maintain patency of the upper airway and diaphragm. level gradually decreased and a hydroxyapatite Raman band at 960 cm – 1 was observed ; and ( iii, iv ) a trend similar to that for debridement occurs following root planing. In addition, at lower levels of fluorescence, hydroxyapatite Raman bands at 440 cm – 1 and 580 cm – 1 and an organic compound Raman band at about 2940 cm – 1 were observed. For this method is useful for quantitatively evaluating the condition of the root surface. We that root surface evaluation using Raman spectroscopy will be used in clinical settings in the PMMA disk inhibited biofilm formation by more than 80 % compared to the uncoated disk, which was also maintained after one week of soaking in water. This study suggests that PMBPAz coating might allow remarkable and durable inhibition of bacterial plaque accumulation on a PMMA surface. easy to use. Dental Hospital work with the cooperation of dentists and dental hygienists in the University Hospital to provide oral health care, which includes not only improvement in oral hygiene but also functional aspects. Last year at the Showa University Fujigaoka Rehabilitation Hospital, oral health care before and after video fluoroscopic examination of swallowing and prosthetic treatment ( to check denture stability ) was implemented, in addition to conventional oral health care. The purpose of this presentation is to report the activity of the Showa University Oral Health Care Center at the Rehabilitation Hospital from April 2014 to March 2015. A total of 100 new patients were seen during the period. Of the 406 attending patients, 149 were seen for conventional oral health care, 126 for oral health care before and after video fluoroscopic examination of swallowing, and 112 for prosthetic treatment. The Showa University Fujigaoka Rehabilitation Hospital is a convalescent hospital where a team approach is used during the period of recovery of activities of daily living, with the cooperation of medical doctors, dentists, nurses, dental hygienists, and speech pathologists. After the patient ' s discharge from hospital, medical cooperation with a private practice becomes important in order to achieve seamless oral health care. This study collected data on endodontic treatments ( total number of treatments, number of root canal-filled teeth, prevalence of pulpitis, and prevalence of periapical periodontitis ) performed from April 2014 to March 2015 on outpatients in the Department of Endodontics at Showa University Dental Hospital. These data were then compared with similar data from a previous study on treatments performed from April to March in 2009 and 2012. The following results were obtained: treatments decreased for teeth with pulpitis and teeth with periapical periodontitis. because the relationship between an existing disease and the current state of oral health or surgery if often unclear. We had rare relationship with Oral surgeon and team approach of several hospitals for us. To improve patient management in these cases, we organized a conference in 2014 to facilitate regular discussion of relevant skills and knowledge. The conference programs are devised mainly based on case results of oral hygienists and oral surgeons working together at the Showa University Yokohama Northern Hospital, with an explanation of the skills involved given by the oral hygienist and a lecture on the relevant disease presented by the oral surgeon. Herein, we report the results of this educational system and of questionnaires against to trouble or self-assessment completed by either 8 oral hygienists who agree to this report beforehand. Impact, were calculated. These scores were compared between pre-treatment and 1 month after the treatment in the group and also compared among the 3 groups using paired t-test and one-way analysis of variance ( p < 0.05 ) . All of 7 denture satisfaction scores improved significantly after the delivery of Nano-zirconia denture, while 4 and 6 satisfaction scores significantly improved for conventional denture with and without metal framework, respectively ( p < 0.05 ) . Regarding OHRQoL, the Orofacial Appearance score was decreased significantly in Nano-zirconia and resin denture groups after the treatment ( p < 0.05 ) . No significant group difference among 3 groups was found for and denture satisfaction and OHRQoL scores. These study results suggested that Nano-zirconia denture, has potential to provide acceptable treatment outcome, which is comparable to conventional denture. The Oral Health Impact Profile ( OHIP ) is one of the most widely used instruments to capture oral health related quality of life ( OHRQoL ) . We have suggested that OHIP consists of four subdomains: " Oral Function " , " Orofacial Pain " , " Oro-facial Appearance " and " Psychosocial Impact " and we believe that evaluation of these subdomains allows better understanding of OHRQoL. The aim of this study was to evaluate the effect of implant treatment by using these four OHIP subdomains. We investigated the hypothesis that the decrease of skeletal muscle mass in older adults with Alzheimer ' s disease ( AD ) is related to not only progression of AD but also decrease of oral function and swallowing function. aimed at maintaining muscle mass. sounds are more effective auditory targets than expiratory sounds alone or swallowing sounds alone in cervical auscultation for detecting dysphagia.


Abstract: The purpose of this study is to discuss Blockchain Technology and the application of Sisko at the Al-Madinah Integrated Islamic School, where the students' cognitive development varies from 4 years to 17 years old. This article uses the library research method which refers to 19 articles downloaded from Google Scholar and Crossref. Blockchain technology is a system that limits its users according to its boundaries but can still be connected with other users. One of the systems for implementing Blockchain Technology at the Sekolah Islam Terpadu Al-Madinah is Sisko SIT Al-Madinah, which contains a database about education from Kindergarten to High School within the Al-Madinah Integrated Islamic School. The menu in the Sisko system is different for each user, for example students use Sisko for exams and assignments, teachers use Sisko to input grades and savings, principals and vice principals use Sisko to manage curriculum, add and edit student data, map students into classes, and finally the Sisko admin uses it to add and edit report formats, map user accounts and archive school databases. Sisko is highly recommended for schools that want to be more effective and efficient in managing data, finances, learning outcomes and in archiving all of their data because schools must be ready to shift into school digitalization in this era.


This chapter seeks to examine the formal network relationships that influence the tourism policy making process. In order to illustrate the complexities of the tourism policy making process and the importance of networks within this context, the chapter provides an empirical analysis of formal tourism policy networks in two Caribbean countries – Jamaica and Trinidad and Tobago. The contributions of this chapter are that it provides both theoretical and methodological approaches for understanding the tourism policy making process. It suggests that policy making is a process that involves certain inputs of policy actors and an output of articulated policies in policy statements. In both Jamaica and Trinidad and Tobago,the low influence of community actors belies the governments' commitment to sustainable, responsible and more inclusive tourism development as enumerated in their tourism policy documents. In order to achieve this vision for tourism development there is a need for both countries to seek to develop and implement strategies that can empower communities so that they can potentially, have greater influence in tourism policy making and by extension, tourism development. With limited community involvement Jamaica's tourism vision for an "inclusive, world class, distinctly Jamaican" industry can be challenged.


Absorption, translocation and metabolism of 2-tret-butyl-4-(2,4-dichloro-5-isopro-poxyphenyl)-Δ2-1,3,4-oxadiazolin-5-one (oxadiazon) in rice plants were investigated. Three types of 14C-labeled oxadiazon were used in this study. 14C-Labeled oxadiazon was applied to soil under submerged conditions and plants were taken for the preparations at various stages of growth and development. Oxadiazon was translocated remarkably to shoots and accumulated in the lower leaves and stems. A small portion of oxadiazon intaken in plants was translocated to head parts. Oxadiazon was chemically transformed in plants to produce dealkylated compounds, oxidized alcohol and carboxylic acid as metabolites. In addition, two unidentified metabolites were detected, one of which was translocated to head parts from leaves and stems. Translocation and accumulation of oxadiazon and its metabolites were discussed in relation to physiological conditions of rice plants.


Islamophobia is on the rise in many Western countries, and while previous research has considered the causes of Islamophobia and the impact it has on its victims, little research has investigated the attitudes and experiences of Muslims who are working to counter Islamophobia, and particularly those of Muslim women. This research investigates the motivations and intentions of Australian Muslim women who run public engagement events for non-Muslims to counter Islamophobia and build social cohesion. Data were obtained via in-depth interviews with 31 Sunni, Shia, Ahmadiyya Muslim women in four Australian capital cities. The three main themes that emerged were that the women wanted to connect with the non-Muslims who attended the events, create positive social change, and increase the knowledge that non-Muslims had about Islam and Muslims. Significantly, the women said that their most important motivator was their faith, and they rejected the idea that they were doing such work to appease non-Muslims. Instead, they saw work was an affirmation of their identity as Muslim women and their commitment to God.


A climate network represents the global climate system as a network where nodes are geographical locations each represented by time-series and edges indicate the interactions of time-series. Network science has been applied to climate data to study the dynamics of a climate network. To enable network dynamics analysis on historical and real-time climate data, the core task is the efficient computation and update of correlation matrices and climate networks. We demonstrate tsupy, a Python library, which extends Jupyter Notebook as instrumentation for performing climate network construction and analysis at interactive speed. This demonstration focuses on how tsupy enables dynamic network analysis on climate data. We also show how tsupy can be applied to neuro-imaging to understand the functional connectivity between brain regions.


In this study we investigated lipid profiles of brain of post mortem type 2 diabetes patients T2DM elderly patients in comparison to a Control group (Co) of the "Netherlands Brain Bank" using LCMS techniques. Here we report that brains of these T2DM patients contain more double bonds and consequently are more rigid. In a small cohort (≈200 patients) we prove that these brain diseases are not interrelated with BMI so obesity is not a major cause. The predicted wave of brain diseases of mild-Alzheimer (m-AD), dementia and depression of the "baby boom generation" might be evolved due to the "fatty" and more "rigid" brain structure due to the quality of fats eaten during earlier lifespan. Our major conclusion is that diabetes and its treatment among T2DM patients are more associated with structural disturbances (lipid composition) in the brain than with glycaemic control. Therefore we introduce the new terminology "Type 3 diabetes" (T3DM) referring to the mental disorders as a consequence of a disordered lipid metabolism in the human brain related to higher degree of unsaturated fatty acids composition.


As relevant reform recommendations flowed from The National Council for Accreditation of Teacher Education, the Goodlad Consortium, the Holmes Group, the Carnegie Forum, and the National Board for Professional Teaching Standards, an experimental teacher preparation program was being envisioned by a large urban school district, a local community college, and a state university. The Teacher Education Alliance (TEA) was developed to prepare pre-service teachers for the 21st century by restructuring teacher preparation curriculum, providing exemplary teaching models, utilizing shared resources, and emphasizing curriculum themes (technology, diversity, and the integration of content knowledge and varied teaching strategies). One of the major postulates to come out of the teacher education reform movement was the importance of school-university partnerships. The Carnegie Report emphasized the importance of a link between a clinical school and university faculty (Darling-Hammond, 1996). Goodlad (1990) advocated the need for higher education involvement in schools and considered serious faculty engagement as the first step. In 1990 a report released by the Florida Education Standards Commission included the recommendation that "a strong collaboration between the colleges of education, colleges of arts and sciences, community colleges, private institutions, the Florida Department of Education, and school districts is essential" (Ishler, Edens, & Berry, 1996, p. 371-372). Burstein, Kretschmer, Smith, and Godoski (1999) suggested "developing a collaborative culture among school and university partners," "establishing cross-institutional positions and school-university committees that govern and guide the collaborative," and "developing differentiated roles and responsibilities for collaborative participants with program decisions made collaboratively" (p. 117). Continued research on the relationship between school-university partnerships and students' learning is recommended (Lawrence & Dubetz, 2001; Lenski, Grisham, Brink, Mahurt, Jampole, Cohen, Mitchell, & Zeek, 2001). The curriculum themes of technology, diversity, and the integration of content knowledge and varied teaching strategies are also supported in the literature. Imig and Switzer (1996) reminded educators of the impact of rapid development of information technologies on teacher education and "... instruction through technology and instruction in the use of technology are becoming important components of programs that prepare teachers" (p. 221). Wiggins and Folio (1999) emphasized that students need to be prepared to teach in culturally diverse settings through teacher preparation programs that infuse multicultural education throughout the total program including multiple approaches, readings, projects, learning in multicultural settings, and immersed field experiences with cooperating teachers who have a thorough knowledge of multiculrural education. Shanker (1996) admonished teacher education for" presenting knowledge in a piecemeal and disconnected manner. Theory is unrelated to practice; content knowledge is disconnected from teaching methods; instructional practices are unrelated to learning and development" (p. 221). This opinion is also advocated by the National Commission for Excellence in Teacher Education (cited in Burnstein, Kretschmer, Smith, & Gudoski, 1999): "Teacher preparation programs often fail to link theory with practice, leave content area knowledge disconnected from methods, and do a poor job of relating instructional practices to learning and development" (p. 109). Darling-Hammond (1996) encouraged the teaching of skills in using a range of teaching strategies including technologies and effectiveness in working with students from diverse backgrounds. After exploring current and proposed elementary curriculum, Ishler, Edens and Berry (1996) set forth five, interrelated conditions and conceptions of elementary education curriculum that should influence teacher education. …


It is controversial whether asymptomatic patients with metabolic evidence of cobalamin (Cbl) deficiency need vitamin treatment. Patients with clinical abnormalities due to Cbl deficiency which are proven to correct with treatment invariably have elevated serum methylmalonic acid(MMA) and total homocysteine(tHcy). However, many subjects with elevated MMA are found in screening studies of seniors and they often have no classical clinical abnormalities. We correlated hematologic and neurologic findings with elevated MMA and tHcy in subjects enrolled in the Northern Manhattan Study. Eligible subjects were over 40 yr, had not had a stroke and lived in Manhattan. Approximately 3000 subjects had serum MMA, tHcy and other relevant data available. The samples were collected from 1993 to 2001 thus spanning food folate fortification in the United States. We analyzed those in the top 1% MMA and/or tHcy since these subjects had values seen also in clinical Cbl deficiency. There were 30 subjects with MMA 975 to 179,900 nM (normal 100fL. The male subject with the highest MCV (109.8 fL), had a hematocrit of 42.7 %, MMA 179,900 nM, tHcy 86.3 uM and Cbl 34 pg/mL with no neurologic findings. Neurologic abnormalities were present in 5 of 30. One subject had high grade spastic paraparesis, 3 had peripheral nervous system deficits, and one had central nervous system defects.Serum tHcy and MMA were not higher in those with neurologic abnormalities. The serum creatinine was 975 nM in 1% of a randomly selected urban multiethnic cohort. 2. Hematologic abnormalities were absent or mild in this group with high MMA. 3. Neurologic abnormalities were found consistent with Cbl deficiency in 17 % of those with high MMA. 4. Both MMA and tHcy are usually elevated. 5. Even though the elevations of MMA and tHcy overlapped those found in clinical studies of Cbl deficiciency these randomly discovered subjects were generally asymptomatic, suggesting that the pathophysiology of megaloblastic anemia and combined systems disease still needs to be investigated.


Micropropagation is a modern and very important technique for increasing the available stock of planting material, especially for newly bred cultivars (Ružic D., Lazic T., 2006). At the Fruit Research Station of Cluj experiments were carried out for the ex-vitro acclimation of black currant plantlets, cultivars Perla Neagra and Amurg, bred at the Fruit Research station. The plants were cultured in vitro for 2 months on modified hormone-free Murashige & Skoog medium (Murashige T., Skoog F.1962,), with 1 mg/l Vitamin B1, 6 g/l Plant-agar and pH adjusted to 5.8, in which they generated very vigorous roots. For the experiment, two types of plant material were used: a) whole rooted plantlets and b) the basal parts of the plantlets containing the roots and 2-3 viable nodes, left in the process of subculturing. For the acclimation phase, two types of solid substrates were used: perlite and a mixture of soil and perlite, 1:1 volume to volume ratio. Both types of plant material was planted ex-vitro into the solid substrates in small plastic trays covered with lids. Trays containing a liquid substrate consisting of a layer of 2-3 cm of plain tap water from Cluj, with the pH=7 were also used for the experiment. Plantlets and plantlet bases were inserted into the liquid substrate and were cultured, in uncovered trays, in direct contact with the surrounding air. After one month of culture, in the case of plant material type a) survival rate in perlite as well as in liquid culture was of almost 100 % and in perlite+ soil mixture it was 95 %. For plant material type b) survival rate in perlite as well as in liquid culture was of 90 %, resulting vigorous shoots from the buds left at the bases. The plants resulting in all experimental variants were planted into pots


In his incomplete article Logical Generality,Frege discussed the problem of generality of thought.He introduced an auxiliary language with a single letter and took it as an approach to research generality thought.In his article,the structure analysis and its truth value condition of generality thought was the content which Frege had not yet finished.The structure of generality thought is unsaturated;meanwhile,its truth value condition may be grasped by understanding the relation of different levels of concept.The first order quantification theory is the key to understand Frege's incomplete article.


The recent implosion of the human embryonic stem cell work of the Seoul National University scientist Woo Suk Hwang has been covered extensively but there is a sidebar: the issue of co-authorship. With the advantage of hindsight, it seems likely that not all of Hwang's coauthors, 14 and 24 of them on the 2004 and 2005 Science papers, respectively, had seen the submitted manuscripts. How frequently is a manuscript submitted for publication without it having been seen by all co-authors? Published corrections can offer some insight. For example, in 2005, the Proceedings of the National Academy of Sciences USA (PNAS) published 80 Corrections. Seventy of these concerned minor mistakes or omissions by the authors, or printer's errors in figures or tables. However, nine of them dealt with the misspelling of an author's name in the published paper (which in one case had the first and last names of an author reversed—how bad is that on the submitting author's part?) and a 10th Correction related to the order of authors. In 2004 there were 87 Corrections, of which seven related to misspellings of authors' names, and another two involved the addition of an author. Co-authors who see a manuscript before submission are quite likely to notice a misspelling of their name. This category of corrections (by no means unique to PNAS, which is an outstanding journal) is therefore a tracer for manuscripts that had not likely been seen by all co-authors. Of course, one cannot discount the possibility that a co-author failed to notice her/his misspelled name in an occasional case. (With a name like mine, I confess to a possible degree of hypersensitivity.) A correction that inserts an additional author obviously signifies that the manuscript had not been seen by that person and also suggests it may not have been seen by other co-authors who might have spotted the omission if the left-out author's work was well recognized in the group. Almost everyone begins the reading of a paper by checking out the title and the author(s). In the aftermath of the Hwang scandal, some in the media have questioned the reviewing policies of Science, unfairly so in my opinion. Numerous experts have stated that they would not have detected the fabrication in the papers as reviewers. Any latent skepticism (e.g., regarding the astonishing large number of human ova obtained and the intensity of effort to achieve success) was dispelled in most people's minds by the widely publicized accounts of the size of Hwang's staff and their 24/7 work style. Most reviewers of the two papers would have had a preconditioned image of a huge team effort. It now appears that the evidence for the properties and even the existence of the claimed cell lines was fabricated. Had all the co-authors seen the manuscripts, it seems likely that at least one of them would have sensed that the presented findings were not what they had seen at the bench, especially in the 2005 paper. Some journals, such as The Journal of Cell Biology, require signed statements from every co-author attesting that they have seen the submitted manuscript. In my own submission practice, my cover letter states that not only have all co-authors seen the final version but that they agree on its content. It may only be a matter of time, in the post-Hwang scandal era, before most journals demand such statements of co-author concurrence upon submission and, although the events that would have precipitated this are unfortunate, it might not be a bad thing. Some journals are now requiring or encouraging coauthors to list their specific contributions, along the lines of "R. B. constructed the type II diabetes transgenic mouse model, K. L. did all the drug injections and tail vein bleedings, F. W. did the glucose tolerance assays and H. T. ran the lab, got the money, is a big enchilada in the diabetes field and wrote the paper—just prior to rushing to the airport with a new PowerPoint slide show in his laptop." (See Nicholas Wade in The New York Times, January 17, 2006, page D2 for a more creative and amusing spoof of this practice.) Though I personally find such tallies stylistically inelegant, their emergence addresses the important issue of defining co-authorship. So let us keep asking ourselves and our colleagues: are you a co-author and don't know it, or shouldn't be an author but are, or want to be an author but aren't, or should have been an author but weren't? Author, author, are you right?


Rapid and readable chromatic detection of antigen is essential for medical and clinical applications as they are inexpensive, portable and simple in operating process. In addition, results from chromatic biosensors can be easily readout without any equipment or instrument collocation. However, only a few studies accomplished the goal by detecting the antigen via this strategy; even though, the detection range is still narrow and only could be applicate on some specific disease identification. Still, most of the chromatic biosensors are continuing color transition and hard to identify the disease at critical point. Therefore, it is essential to develop a wide-detecting ranged or detecting range tunable chromatic biosensor revealing considerably color-change for numerous diseases recognition. This article presents a detection range tunable readable chromatic biosensor for antigen detection, demonstrated by the detection of human serum albumin (HSA). First, the HSA sample was pre-conjugated to chitosan to form HSAchitosan complex, then, the HSA-chitosan complex was utilized to synthesize Ag NPs. According to the color shown by the synthesized Ag NPs, 0.01-0.3 mg/ml HSA sample could be determined. Furthermore, the detection range could be adjusted to 0.001-0.1 or 0.1-1 through decreasing or raising the chitosan-conjugating concentration, showing the potential for more disease identification application.


Allelopathic interactions, mediated through chemicals released by one plant, affects the growth and development of other plants growing in the vicinity. A great diversity of plants including trees exhibit allelopathy and the chemicals involved in this process are known as allelochemicals. These allelochemicals are released from the plants through leachation, decomposition of fallen plant parts, root exudation or as volatile components from aromatic plants. Among different allelochemicals, essential oils are one of the major constituent of number of higher plants, and are obtained by the process of steam distillation. The volatile and aromatic nature of essential oils helps in attracting pollinators, plantplant signaling and tritrophic interactions. Essential oils are being investigated for their phytotoxic effect so that they can be used as potential herbicides.


Space weather storms typically have solar, interplanetary, geophysical and societal-effect components that overlap in time, making it hard for students and novices to determine cause-and-effect relationships and relative timing. To address this issue, we use timelines to provide context for space weather storms of different intensities. First, we present a timeline and tabular description for the great auroral storms of the last 500 years as an example for space climate. The graphical summary for these 14 events suggests that they occur about every 40–60 years, although the distribution of such events is far from even. One outstanding event in 1770 may qualify as a one-in-500-year auroral event, based on duration. Additionally, we present two examples that describe space weather storms using solar, geospace and effects categories. The first of these is for the prolonged storm sequence of late January 1938 that produced low-latitude auroras and space weather impacts on mature technology (telegraphs) and on high frequency radio communication for aviation, which was a developing technology. To illustrate storm effects in the space-age, we produce a detailed timeline for the strong December 2006 geomagnetic storm that impacted numerous space-based technologies for monitoring space weather and for communication and navigation. During this event there were numerous navigations system disturbances and hardware disruptions. We adopt terminology developed in many previous space weather studies and blend it with historical accounts to create graphical timelines to help organize and disentangle the events presented herein.


ABSTRACT Modern concepts concerning the origin of oil and gas are reviewed. Emphasis is stressed on those sedimentary environments under which conditions are most favorable for not only the origin but also the accumulation and preservation of major hydrocarbon reserves. Over 90 percent of the oil and gas discovered to date has been found in four different sedimentary environments. The deltaic complex, in particular the delta margin environment, is probably the most favorable of these four environments. Second is the rapidly subsiding carbonate shelf or lagoon where carbonate and/or evaporite sedimentation keeps pace with subsidence. Third is the reef complex associated with the carbonate shelf. Fourth is the turbidite environment which includes all gravity-induced submarine flows, both arenaceous and carbonate. These favorable sedimentary environments are described, and the paleontologic and lithologic criteria useful in the recognition of each are reviewed. Major reserves found in basins of the free world are documented according to sedimentary environments. End_of_Record - Last_Page 82--------


The lipid content of thylakoids from dark-treated oat plants was studied. The levels of chlorophyll, monogalactosyl diacylglycerol2, digalactosyl diacylglycerol, and the phospholipids all declined. The lipids declined more rapidly than the chlorophyll. As the quantity of the galactolipids declined, there was little change in the relative concentration of linolenic acid esterified to them. In contrast, the relative concentration of linolenic acid esterified to the phospholipids increased as the quantity of lipid declined. The total fatty acid composition and the incorporation of label into thylakoid lipids dropped following the dark treatment.


In this paper we introduce homogeneity for hybrid systems (using generalized dilations) and provide basic implications of this property similar to that of continuous-time and discrete-time homogeneous systems. In our main result we state that stability of a hybrid system that is robust with respect to small perturbations implies the existence of a homogeneous Lyapunov function for the system. This converse Lyapunov theorem unifies the previous results


SUMMARY This study proposes a novel machine learning architec- ture and various learning algorithms to build-in anti-phishing services for avoiding cyber-phishing attack. For the rapid develop of information tech- nology, hackers engage in cyber-phishing attack to steal important personal information, which draws information security concerns. The prevention of phishing website involves in various aspect, for example, user training, public awareness, fraudulent phishing, etc. However, recent phishing re- search has mainly focused on preventing fraudulent phishing and relied on manual identification that is ine ffi cient for real-time detection systems. In this study, we used methods such as ANOVA, X 2 , and information gain to evaluate features. Then, we filtered out the unrelated features and ob- tained the top 28 most related features as the features to use for the training and evaluation of traditional machine learning algorithms, such as Sup- port Vector Machine (SVM) with linear or rbf kernels, Logistic Regression (LR), Decision tree, and K-Nearest Neighbor (KNN). This research also evaluated the above algorithms with the ensemble learning concept by combining multiple classifiers, such as Adaboost, bagging, and voting. Fi- nally, the eXtreme Gradient Boosting (XGBoost) model exhibited the best performance of 99.2%, among the algorithms considered in this study.


Abstract Spexin (SPX) is a novel adipokine playing an emerging role in metabolic diseases due to its involvement in carbohydrate homeostasis, weight loss, appetite control, gastrointestinal movement, among others. Moreover, plasma levels are reduced in obese and type II diabetic patients. In vitro, SPX favors lipolysis in adipocytes and hepatocytes and inhibits white adipogenesis. Therefore, the aim of this study was to evaluate the role of SPX in white adipose tissue (AT) thermogenesis. C57BL/6J male mice were treated or not with SPX for ten days (ip. 29 µg/kg/day; CTR and SPX). At day 3 mice were randomly divided: a group was kept at room temperature (RT) and the other at 4°C to stimulate thermogenesis (CTR-C and SPX-C). Caloric intake and body weight was daily recorded. At the end of the protocol plasma, Brown AT (BAT), abdominal AT (Epidydimal, EAT) and subcutaneous AT (Inguinal, IAT) depots were collected for several measurements. We found that caloric intake was increased when animals were exposed to cold (P<0.001). Body weight change revealed a differential effect of SPX depending on temperature (interaction SPX x Cold, P<0.05): SPX animals weighted less than CTR at RT, but upon cold stimulation there was no difference. No changes were observed for plasma glucose levels, however plasma triglycerides (Tg) levels decreased after cold exposure regardless SPX treatment (Cold P<0.01). Liver Tg content showed a SPX x Cold interaction effect (P<0.0001), where, upon cold stimulation, CTR-C animals increased their levels, but on the contrary SPX-C mice decreased it. EAT, IAT and BAT relative mass showed an interaction effect of variables (SPX x Cold P<0.05). When compared upon cold, SPX-C mice had less AT mass compared to CTR-C mice. IAT and EAT mRNA expression of UCP1 and Cox8b showed SPX x Cold interaction (P<0.05), with a tendency of reduction or no difference in SPX at RT, but with a significant decrease in SPX-C compared to CTR-C mice upon cold exposure. PGC1a expression was increased in EAT from cold exposed-mice and in IAT only in CTR-C mice. UCP1 protein levels showed different results depending on the AT depot. For IAT SPX x Cold interaction (P<0.05) was observed, where SPX inhibited UCP1 stimulation only upon cold exposure. On the contrary, for EAT UCP1 levels decreased in SPX-treated mice, regardless cold exposure (SPX P<0.05). In conclusion, SPX treatment in vivo reduced the thermogenic process in subcutaneous and abdominal AT, being more evident upon cold stimulation. PICT2017-2038, PICT2017-2314.


Guided waves attenuate seriously on some structures, such as carbon fiber composite structures. Specially, the low signal to noise radio (SNR) of guided waves, resulting from high attenuation, limits the accuracy of guided waves based methods. Among them, sensor array based imaging methods have been gradually studied to synthetic guided waves from different excitation-sensing paths, which could improve the SNR of guided waves to some degree. However, these methods usually synthetic guided waves on only the excitation or sensing side, which are still not enough for high attenuation structures. To solve this problem, an improved MUSIC damage localization method with transmitter beamforming is proposed in this paper. Transmitter beamforming is carried out to make the excitation guided waves focused on special positions and MUSIC algorithm is used to synthetic the received guided waves, scattered from damage, to further improve the damage imaging accuracy. At last, an experiment on the carbon fiber composite plate is carried out to verify this proposed method. Experimental results show that the proposed method can realize accurate damage imaging with the angle errors less than 2° and the distance errors less than 30mm.


The aim of this group continues to be to study some of the fundamental properties of gas discharge physics by means of microwave plasmas, with more and more emphasis on high-density plasmas and plasmas in magnetic fields. To carry out this general objective, we have spent a great deal of effort on the production of plasmas of highpercentage ionization at low pressures under steady-state conditions, the achievement of which will allow us to carry on the fundamental studies in which we are most interested. At the present time, we have not produced plasmas with as high percentage of ionization as we had hoped to, but we have several schemes underway for producing them. We are also studying ways of determining the characteristics of the plasmas by means of microwaves, spectroscopic methods, and the diamagnetic effect of the electrons. Along with these production and diagnostic studies, we are continuing measurements on fundamental physics studies of collision cross sections, loss mechanisms, and gain mechanisms of the electrons in the plasmas. S. C. Brown


To approach enssence of channels and collaterals.On the basis of biophoton coherence theory,according to the theoretical arithmetic of simplified model and oppose to the experimental result.Result show that photon radiation field inside the organism can produce strong interference phenomenon.According the result,we give the channels and collaterals hypothesis: photon radiation field within human body is characterized by non-local interference,resulting in interfering phenomena throughout the human body.The interfering beams form a whole network of solidarity,distributing strips(beams) of varied intensity on the surface of body.The beams are channels and collaterals.They carry corresponding biological information and link the tissues and organs within the body.