Serverless computing is a new paradigm that aims to remove the burdens of cloud management from developers. Yet right-sizing serverless functions remains a pain point for developers. Choosing the right memory configuration is necessary to ensure cost and/or performance optimality for serverless workloads. In this work, we identify that using parametric regression can significantly simplify function rightsizing compared to black-box optimization techniques currently available. With this insight, we build a tool, called Parrotfish, which finds optimal configurations through an online learning process. It also allows users to communicate constraints on execution time, or to relax cost optimality to gain performance. Parrotfish achieves substantially lower exploration costs (1.81-9.96 × ) compared with the state-of-the-art tools, while delivering similar or better recommendations.


This study investigated the distribution of spotted seals, Phoca largha, inhabiting the coast of Baekryongdo. Monitoring of spotted seals in Baekryongdo was conducted between June 2006 and November 2008, using a 5-ton fishing vessel 1hour before low tide. The monthly maximum number of observed seals was 274 in September 2006, 139 in September 2007, and 213 in August 2008. Average observed monthly counts were largest in August and September. Relatively more spotted seals were observed when there were few cloudy days and plenty of sunshine. Bycatch, stranding, and observations of spotted seals have been reported along the coast of the Korean peninsula since 2000, and spotted seals were observed four times in the western coastal region, three times in the southeastern region, and 12 times on the east coast. This suggests that spotted seals inhabiting Baekryongdo migrate to the East Sea via the West and South seas as individuals or in groups.


Both the Underbed and Overbed coal feed systems have been developed to industrial practice and are used in presently installed fluidized combustors. The arguments developed in this paper are based on the premise that the need for feeding the coal at a number of points into the fluidized bed is primarily due to the coal volatiles which may evolve fast after the coal's injection, relative to the dispersion of the coal from a feed point. The purpose of this paper is to provide a quantitative basis for the design of coal feed system by considering the relative rates of coal devolatilization and particle mixing in the bed and the freeboard, as affected by fluidized combustion operating variables. For the underbed feed model for calculating the oxygen requirement for volatile combustion in the volatile release of the bed has been developed. Three bituminous coals and one lignite were chosen to study the variation of oxygen requirement with coal types. The model is capable of being used for determining whether sufficient oxygen is supplied to the volatile release zone so as to avoid overbed burning of volatiles, and for the design of spacing between coal feed points for different coal types. Formore » the overbed feed a volatile release model for a spreader feeder in the freeboard of a fluidized bed coal combustor has been developed. Particle trajectories, residence times of the particles in the freeboard, and the amount of volatiles released during the period of time were determined for the effects of spreader feeder design parameters and coal feed particle sizes. 14 figures, 4 tables.« less


Look upon the phenomenon of war with dis passion and detachment, as if observing the follies of another species on a distant planet: From such an elevated view, war seems a puny enough pastime. Demographically, it hardly mat ters. War deaths amount to something like 1 per cent of all deaths; in many places, more die by suicide, and still more in accidents. If saving hu man lives is the great desideratum, then there is more to be gained by prevention of drowning and auto wrecks than by the abolition of war. But no one on this planet sees war from such a height of austere equanimity. Even the gods on Olympus could not keep from meddling in earthly conflicts. Something about the clash of arms has a special power to rouse the stronger emotions?pity and love as well as fear and ha tred?and so our response to battlefield killing and dying is out of all proportion to its rank in ta bles of vital statistics. When war comes, it mus cles aside the calmer aspects of life; no one is un moved. Most of us choose one side or the other, but even among those who merely want to stop the fighting, feelings run high. ("Antiwar mili tant" is no oxymoron.) The same inflamed passions that give war its urgent human interest also stand in the way of scholarly or scientific understanding. Reaching impartial judgment about rights and wrongs seems all but impossible. Stepping outside the bounds of one's own culture and ideology is also a challenge?not to mention the bounds of one's time and place. We tend to see all wars through the lens of the current conflict, and we mine history for lessons convenient to the pres ent purpose. One defense against such distortions is the sta tistical method of gathering data about many wars from many sources, in the hope that at least some of the biases will balance out and true patterns will emerge. If s a dumb, brute-force approach and not foolproof, but nothing else looks more promis ing. A pioneer of this quantitative study of war was Lewis Fry Richardson, the British meteorolo gist whose ambitious but premature foray into nu


Critical Care Medicine www.ccmjournal.org 1367 The ICU is considered the ultimate area for care of the critically ill. Intensivists focus on ICU occupancy (1), length of stay, manpower, care models, bundles, and mortality. In contrast, intensivists do not commonly consider the nuances of critical care delivery in the emergency department (ED), a primary source of ICU patients. ED clinicians, however, have sought for many years to increase their skill sets in critical care and contribute to the field by participating in critical care medicine (CCM) fellowship training programs (2, 3) and sepsis research (4, 5). Despite ED involvement in CCM, we are left with several important questions in regard to ED care of the critically ill. How do we nationally identify critically ill ED patients? What proportion of ED patients are critically ill? Are the critically ill ED patients expediently transferred to the ICU? And, have these patterns changed over the last decade? There are no national databases that track critically ill ED patients. The American Hospital Association (6) and Healthcare Cost Report Information System (7), the two most wellknown nationwide hospital datasets, do not compile ED data beyond overall ED utilization (American Hospital Association) and expenses (Healthcare Cost Report Information System). Therefore, the critically ill ED patients must be identified from other hospital datasets using proxy measures derived from ED stays. These may include billing and diagnostic codes, triage scoring, resource utilization, procedures, and patient disposition. Each proxy parameter, however, is problematic. Billing and diagnostic codes may represent critical care and illness as long as CCM coding is applied correctly. An increase in the use of CCM billing and diagnostic codes may indeed indicate an upswing in the incidence of critical illness; however, it may also reflect enhanced coding expertise concomitant with the prospect of better reimbursement. The use of non-CCM billing codes for critically ill either by inexperienced ED clinicians and coders or by hospital-based restrictions on the use of CCM billing codes may lead to underestimation of the critically ill in the ED. Similar issues may exist in regard to diagnostic coding. Triage scores at ED presentation are a poor proxy because multiple scoring systems exist, and values at initial triage may not reflect clinical deterioration during the ED stay. Resource utilization (laboratory and imaging studies) is a troublesome critical illness indicator because many ED patients undergo extensive evaluations, but may not be critically ill. Alternatively, critically ill ED patients may already have had diagnostic workup prior to ED arrival or are too sick to undergo studies and are admitted expediently to the ICU. ED procedures (intubation, central venous access) are reliable identifiers for the most critically ill; however, ED patients may already have indwelling central venous access or are admitted to the ICU with lower acuity levels that do not require invasive procedures. Identifying ED patients as critically ill using ICU admission as the ED disposition may be the most elegant proxy. However, this parameter may be tricky because hospital datasets commonly do not provide clear directions for applying this field and the CCM community has long struggled to define what types of units should be included in the term ICU (1) (i.e., coronary care or step-down units). The ED to ICU disposition proxy may also underestimate the number of critically ill ED patients if very sick ED patients were transferred directly to the operating rooms, cardiac catheterization laboratories, interventional radiology suites, inpatient wards, or regional ICU medical centers. This proxy will also miss critically ill patients who expired in the ED. The ED to ICU proxy may also overestimate the number of ED critically ill patients if the number of ICU beds increased resulting in more relaxed triage and ICU admissions of low acuity patients. Despite the plusses and minuses of these ED critically ill proxies, the good news is that all of these possible parameters are available from the National Hospital Ambulatory Medical Care Survey of the Centers for Disease Control and Prevention (http://www.cdc.gov/nchs/ahcd.htm). This annual survey is conducted in selected hospitals (geographically disbursed mix of urban and rural, large and small, nonfederal, short stay, and general hospitals) on random ED patient visits during a random 4-week period each year. At this time, data is abstracted from the ED records, placed into the National Hospital Ambulatory Medical Care Survey-100 (ED) data collection form (8) and subsequently validated, inflated, and weighted to produce national unbiased estimates representative of ED visits in the United States (9). In this issue of Critical Care Medicine, Herring et al (10) have enhanced our understandings of critical care in the ED through their retrospective 8-year (2001–2009) analysis of National Hospital Ambulatory Medical Care Survey data. Critical Care in the Emergency Department: It's Critical to Know What's Going On!*


Abstract The massive traumatization of World War I combat soldiers led to an unprecedented incidence of somatoform dissociative disorders and symptoms, usually diagnosed as hysterical disorders during the war years. Following a brief overview of the scope of the suffering during this Great War, attention is given to British army psychiatrist Charles S. Myers' (1940) observations of the alternation between a so-called "emotional" personality and an "apparently normal" personality in traumatized combat soldiers. Somatoform dissociation, further categorized into positive and negative symptoms, is related to this structural dissociation, and to fixation in the trauma and avoidance of the trauma, and may be part of a more encompassing symptomatology. Next, a short overview of diagnostic issues is given. We argue that the DSM-IV category of "conversion disorder" is incorrect. Rather, the findings revealed here support Janet's classic and Nijenhuis' more recent views on somatoform dissociation. Finally, treatment issues are briefly presented.


Nitration of 1-arylpyrroles 1a-c with acetyl nitrate, and 1-arylpyrroles, 1a-e and 1-(2-ethoxycarbonylbenzyl)pyrrole 4 with trifluoroacetyl nitrate gave the corresponding 2-nitro isomers 2a-e and 5, and 3-nitro isomers 3a-e and 6. 3-Nitropyrroles 3d and 3e were further nitrated with a mixture of nitric and sulfuric acids to give compounds 10, 11 and 12, respectively. Under the same conditions 1-(2-ethoxycarbonylbenzyl)-3-nitropyrrole 6 gave derivative 13.


Graphene–silicon (Gr–Si) Schottky junction solar cells have recently attracted intensive attention as candidates for low-cost photovoltaic devices. However, the efficiency of Gr–Si solar cells still needs further improvement. In this study, we have introduced an ultra-thin LiF layer between the Si and aluminum (Al) back electrode of Gr–Si solar cells. It is found that carrier recombination at the back surface is significantly suppressed, resulting directly in the improvement of external quantum efficiency (EQE) of devices in the long wavelength range of 800–1100 nm. Moreover, the back contact resistance is greatly reduced, and therefore the fill factor (FF) of devices is greatly improved. As a result, the highest power conversion efficiency (PCE) of 6.25% has been obtained for a pristine Gr–Si solar cell, which is further improved to 10.61% after chemical doping. These results pave a new way to the fabrication of high efficiency Gr–Si solar cells.


The background of this research is that Pesisir Barat Regency is prone to landslides, so that landslide disaster mitigation efforts are needed using the local wisdom of RepongDamar. The purpose of this study was to determine the role of RepongDamar in landslide disaster mitigation. The method used in this study is a qualitative method with a descriptive approach. The results of the study describeRepongDamar's role in landslide disaster mitigation efforts includes the role of the canopy as a water reservoir, thereby reducing the amount of rainwater that reaches the ground. The second role is that large roots will have a grip on the soil which can reduce the possibility of soil movement and increase the shear strength of the soil. The third role, evapotranspiration plays a role in reducing soil saturation, so that water does not accumulate in the impermeable layer. The existence of RepongDamar will minimize the occurrence of erosion, because RepongDamar has woody trees that have strong roots such as damar, duku, petai, jengkol, teak and durian trees.


Synopsis-The maior variables associated •vith control of MICROBIAL GROWTH and antimicrobial action in COSMETICS are considered. Some factors of special importance for preservative effectiveness are pH, solubility of the preservative in the aqueous phase and its partition between water and oil phases, interference with antimicrobial action by other components of the formulation, and enhancement and synergism. The advantages and disadvantages of approximately a dozen PRESERVATIVES generally accepted for use in cosmetic preparations are briefly reviewed.


Until recently clinicopharmacological studies in psychiatry have aroused little research interest. In the last few years, however, progress in clinical psychopharmacology has led to new methods of clinical therapeutic research which have been widely accepted. This research continues to build, however, mainly on clinical observations since it is not yet possible to find a way to apply in man pharmacological models of peuroleptics such as their effect on central receptor mechanisms. Perhaps further studies of their effects on monoamine metabolism and on the endocrine system may change this situation (Cotes et al. (1978)). The elucidation of the effect of neuroleptics must, therefore, be based on their effects on single symptoms and symptom clusters and on side effects and clinical global assessment. Thus symptom scales are essential for such research. About 15 years ago the symptom scales as an instrument of assessment competed with psychological tests which measured learning, reaction time, memory, etc. However, such psychological tests turned out to be of little value because Of poor reproducability and poor correlation with clinical symptoms. Thus symptom scales, though only rough instruments, came to dominate the process analysis of clinical therapy. However, critisism has been made of their value (see also Guilford (1954)): 1. From a validity point of view they may fail in relevance, in discrimination, and in predictive value and thus they do not measure what is intended. This applies to both diagnosis and rating of therapeutic effect. 2. Their reliability is doubtful which limits their use in the evaluation of the effects of treatment. Both the interand intrarater reliability therefore needs to be determined as a preliminary to any clinical trial. 3. Their correlation with a clinical global assessment and patients' own evaluation (Katz (1970)) is uncertain.


Uranium metal and oxidised uranium metal surfaces have been examined by use of Auger electron spectroscopy. The methods used to obtain clean and oxide-free uranium metal surfaces are discussed together with the changes in the Auger spectra on oxidation. Chemical shifts in the uranium Auger peak positions resulting from changes in the electron energy levels in neutral uranium and uranium(IV) have been predicted by use of the electron binding energies determined by X-ray photoelectron spectroscopy.


Polymorphonuclear neutrophils (PMNs) play a crucial role in the innate
immune system's response to microbial pathogens through the release of reactive nitrogen species,
including Nitric Oxide (NO).

Methods: In neutrophils, NO is produced by the inducible Nitric Oxide Synthase (iNOS), which is
regulated by various signaling pathways and transcription factors. N-nitrosodimethylamine
(NDMA), a potential human carcinogen, affects immune cells. NDMA plays a major part in the
growing incidence of cancers. Thanks to the increasing knowledge on the toxicological role of
NDMA, the environmental factors that condition the exposure to this compound, especially its precursors-
nitrates arouse wide concern.

 In this article, we present a detailed summary of the molecular mechanisms of NDMA's
effect on the iNOS-dependent NO production in human neutrophils.

 This research contributes to a more complete understanding of the mechanisms that
explain the changes that occur during nonspecific cellular responses to NDMA toxicity.


The technology and some properties of a new high-purity molybdenum alloy doped with Ti and Zr are described. With the help of double vacuum melting polycrystalline ingots of 110 mm in diameter were obtained. Throughout the work the chemical composition of the ingots was homogeneous as well as the grain structure, however, this drastically differed from coarse polycrystals usually obtained in analogous conditions. As a result of hot pressing, rolling, forging or drawing the bars, sheets, wire or thin foil may be easily obtained. It was shown that texture homogeneity was of great importance in order to produce thin foils of a good quality. Due to a very small amount of interstitials in the alloy a high plasticity of relatively dilute solid solution was found together with sufficient high-temperature strength due to special hardening operations after the end of plastic deformation. Thin current leads (0. 028 x 2.8 mm cross section) for quartz lamps were obtained. It was shown, that the recrystallization temperature of the alloy was strongly dependent on the oxygen pressure during annealing. Both the sheets and wires have been easily strengthened due to the dispersed oxides formation during annealing in controlled conditions (temperature and furnace atmosphere).


We read with great interest the report of Erro and colleagues titled "Severe Dyskinesia After Administration of SARS-CoV2 mRNA Vaccine in Parkinson's Disease" in which they report two patients with Parkinson's disease (PD) who developed severe dyskinesia after receiving the BNT162b2 mRNA vaccine. We would like to comment on our experience trying to assess whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have any positive or negative impact on motor symptoms in patients with PD. We reviewed the medical dossiers of more than 200 consecutive patients with PD followed in the past 2 months by telemedicine because of the pandemic and who had already received one or two doses of any of the SARS-CoV-2 vaccines available in Peru (BNT162b2 [Pfizer/BioNTech, USA] and BBIBP-CorV [Sinopharm, China]). We specifically searched for any variation on motor symptoms including dyskinesia for at least 3 days after any of each dose. A total of 181 patients with PD met the inclusion criteria; 107 men and 74 women were included. Mean age was 65 years old (range, 31–99). A total of 178 patients received two doses of the SARS-CoV-2 vaccine (177 Pfizer/BioNTech and 1 Sinopharm), and three patients received only one dose of the Pfizer/BioNTech vaccine. A total of 11 patients (6%) had COVID-19 during the pandemic. The effect of the infection on parkinsonian symptoms was not evaluated for this report. Only two patients (1.1%) reported some degree of deterioration following one of the doses of the vaccine. The first patient presented with increased rigidity and gait impairment soon after the first dose that lasted a few days. The second patient presented with increased resting tremor that lasted for 2 weeks also after the first dose. In both cases, symptoms improved spontaneously without any modification of their antiparkinsonian medications. No one reported the appearance or increase of dyskinesia. Studies focusing on the relationship between SARS-CoV-2, COVID-19, and PD have provided conflicting results. The approved mRNA-based and viral vector vaccines are not expected to interact in PD but have created some concerns with regard to the benefits and risks. These vaccines are not known either to interfere with the neurodegenerative process or modify motor symptoms or the response to current therapies for PD. Nevertheless, some patients have developed exacerbation of motor symptoms or severe dyskinesia after vaccination, and the reasons remain unclear, but they might be explained by triggering a systemic inflammatory response, excessive anxiety, or due to an interaction with regular antidopaminergic medication. These cases, even if they represent a very low incidence, should not discourage patients to receive vaccines, and we recommend people with PD COVID-19 vaccination with approved vaccines unless there is a specific contraindication.


Work on the Expert System for Chemistry began when one of the authors had occasion to attempt the use of existing programs for planning chemical transformations and realized the difficulty of making even small changes in a 60,000 line FORTRAN program. The authors describe here the resulting program which is written largely in the production rule based language OPS5.


Over forty years ago Curriculum Inquiry published Jean Anyon's (1981) "Social Class and School Knowledge." Anyon (1981), influenced by contemporary theories of social reproduction and other curriculum scholarship, employed a Marxist class analysis to examine working, middle, affluent, and elite classes of schooling to understand how the standard curriculum reproduces itself in and through its subjects. What Anyon (1981) learned was that the contradictions within and between social groups reproduced ideology but also resisted its reproduction. Anyon (1981) called this resistance to ideological and class reproduction nonreproductive possibilities and knowledge that "facilitates fundamental transformation of ideologies and practices" (p. 31). Anyon's (1981) foundational work meant that no longer could schooling be the great equalizer if more knowledge is not the answer to increasing economic access. Anyon's work influenced generations of scholars to question the values and value of schooling from within its contradictions towards more equitable futures through social change, a tradition that Curriculum Inquiry remains invested in and that the articles in this issue continue to examine. One recent work that draws briefly on Anyon's (1981) work with the same spirit of interrogating schooling and social transformation, but from a decolonial ethic, is la paperson's (2017) A Third University is Possible. For la paperson (2017), the university is a worlding or "world-making" (p. xiv) formation that consists of three entities. The first world university aims to actualize imperial colonial futures of a settled world. The second world university aims to humanize and include the world it had formerly excluded, but in the end, remains a colonial institution but will a gentle touch (i.e., liberal multiculturalism or settler reconciliation). Drawing on Deleuze and Guattari (1983), la paperson (2017) framed the third world university as a kind of desiring machine or a multiscalar assemblage driven by decolonial desires for Indigenous, Black, brown, and queer futures, the rematriation of land, and regenerating relationships broken through colonization and global, always racial, capitalism. Importantly, for la paperson (2017), colonial first and second world universities harbor antiand decolonial resistance. For example, drawing on postcolonial thinker and novelist Ngũgĩ wa Thiong'o, la paperson (2017) reminded readers that British colonial schooling in Kenya harbored to-be revolutionaries and the critical eye of Thiong'o himself. In other words, the first and second world colonial universities "carry decolonial riders ... [with]


Proposals for radical NHS reform by the UK's Secretary of State for Health provoked such a storm of protest and concern that the prime minister appeared on breakfast television and, on the same day, published an opinion piece in The Times newspaper to defend them.1 By this point, the rationale for reform had mutated into a combination of saving money and simultaneously improving health outcomes – both of which have to be achieved in the context of changing demography and disease epidemiology, rampant technology, rising patient expectations, and shrinking resources.

The reforms were needed, the government claims, because we are performing worse than many of our European neighbours. The data used to make this case, however, are a couple of years old and the claims of inferior 'amenable mortality'2 have since been challenged. Appleby has shown that UK health outcomes for heart disease, for example, have now almost converged with those in France – where outcomes are reckoned to be good – and at lower cost.3 Similar trends are apparent for lung cancer. Cooper et al have documented that waiting times for knee, hip, and cataract surgery have greatly improved, without any evidence of widening health inequities.4 Access to diagnostic and treatment facilities for cancer have also improved, and …


In this paper, we are going to discuss what led Spain to carry out a
constitutional reform. The reform that occurred was voted in with a large
majority, however it also received a lot of criticism from the formal aspect and
opportunity.
The reform was brought on because of the economic crisis and the
European conception of facing it. The aim was to combat the crisis from
economic principles such as budgetary stability. The European Union requires
Member States to meet deficit and debt requirements. The ratio of the annual
government deficit to gross domestic product (GDP) should not exceed 3% at
the end of the preceding financial year and the ratio of gross government debt
to GDP should not exceed 60% at the end of the preceding financial year. Being
outside such ratios can even entail sanctions.
At the end of the article an analysis of the Japanese financial situation can
be found, where the difference in debt ratios that far exceed the limits envisaged
by the European Union can be seen.


This paper presents a measurement module for Wireless LAN card working in IEEE 802.11b together with an implementation, measurements and overall QoS architecture in ad-hoc mode. In this mode the wireless card allows for best-effort services transfer using IEEE 802.11 MAC layer DCF function. In order to support services with defined QoS level in IEEE 802.11b network, prior implementation of accurate measurement module to obtain the congested status of the shared medium access cooperating with higher layer applications is required. To evaluate the performance of the measurement module, we present the results obtained during measurements and integration tests.


Two hundred ninety-three peanut accessions were screened for resistance to the peanut root-knot nematode using visual galling and egg-mass ratings. Staining with phloxine B greatly expedited the egg mass screening process. No high level of resistance was observed in any of the accessions evaluated


Objective: To survey the application of caspofungin in our hospital and provide reference for rational use in clinic. Methods: A total of 156 cases using caspofungin were extracted from January 2011 to March 2012 and retrospectively analyzed in respect of the number of use of caspofungin in different wards, situation of medication, clinical efficacy and adverse reactions. Results: Among 156 cases of application of caspofungin, the usage and administration in 141 cases complied with the specification of caspofungin, the loading doses and maintenance doses in 3 children patients were reduced, both of the maintenance doses and loading doses in other 12 cases were 70 mg. The highest frequent use of caspofungin was respiratory department(38 cases, accounting for 24.36%), followed by hematology department(31 cases, accounting for 19.87%) and cardiovascular department(17 cases, accounting for 10.90%). After application of caspofungin treatment, the total effective rate was 51.93%, and in the course of treatment no serious adverse reaction was found. Conclusion: Caspofungin was relatively safe and effective for the treatment of invasive aspergillosis, invasive candidiasis as well as candidemia.


The purposes of this study for knowing how to improve the character of academic atmosphere to improve the ability in designing geometry learning on Study Program of Elementary School TeacherUniversitas Negeri Semarang students. This research is a classroom action research conducted in two cycles and each cycle consists of two meetings. Each cycle consists of planning, execution, observation, and evaluation. The subjects of this study are lecturers of geometry and students who take geometry course. The technique in collecting data is using test and non-test techniques. The data analysis is done in quantitative and qualitative descriptive analysis. The result of research shows that the lecturers' activity is in good category and student activity is on very good category. While the students' learning outcomes are in good category. From the field notes, students are able to perform independent and structured tasks with their full responsibility, hard work, and diligence. It shows that the character of academic atmosphere has increased. It is suggested that a set of task bills so that prerequisites have been owned by the students. Structured tasks should be given to see the students' ability.


APRILab WP1 starts from the hypothesis that to address the intervention dilemma, any planning process needs to integrate the capacity to combine, integrate and flexibly navigate between the open and close contours of intervention processes throughout time and space. For this sake we have investigated the incremental progress of the project management both in terms of programming (time) and definition of areas of target (space). In particular, we assume that, despite its capacity of responsiveness and engagement, elements of 'spontaneity' actually might lead to situations of uncertainty and un-control in urban intervention, and create disengagement between short term outcomes and long terms objectives (time), as well as between micro-practices and larger dynamics (space).


ABSTRACT Registered dietitian nutritionists (RDNs) are experts in a wide range of food, health and nutrition topics. RDNs also play an important role in supporting sustainable food systems. However, not all RDNs and other food system stakeholders realize RDN's role in supporting sustainable food systems – applying a skillset that is central to the RDN profession. Using the lens of the five professional entry points identified by the Cultivating Sustainable Food and Water Systems: A Nutrition-Focused Framework for Action, we provide a snapshot of how a clinical, retail and public health dietitian support sustainability in their local food system every day.


Mathematical statistical analysis of inductive loop coil-sensor is carried out for its magnetic field effects operating on extremely low frequency (<30Hz). A system using resister, inductor, and capacitor effects finds resonance frequency for this loop sensor and its sensitivity as ferromagnetic effect. The design methods for these coils with air and ferromagnetic cores are technically compared and summarized, which are also known and used as search coils or pickup coils or magnetic loop coil sensors. The amplitude and bandwidth of the frequency components are compared to the standardized normal spectrum. This paper also presents the applications of coil sensor as magnetic coil.


The article studies theoretical and methodological approaches of subjective and objective idealism, General scientific subjective and consumer methodological approaches, analyzes the scientific positions of economic schools of mercantilism and marginalism, considers the views of the economic school of physiocrats, the ideology of objective rationalism of classical political economy. In the course of theoretical research, the process, tendency and regularity of transformation of the main principles of subjective and objective idealism into the basic characteristics of consumer and system methodological approaches, which are the basis for evaluating the economic efficiency of investment projects, are established.


The wide spread of coronavirus (COVID-19) has threatened millions of lives and damaged the economy worldwide Due to the severity and damage caused by the disease, it is very important to fore-tell the epidemic lifetime in order to take timely actions Unfortunately, the lack of accurate information and unavailability of large amount of data at this stage make the task more difficult In this paper, we used the available data from the mostly affected countries by COVID-19, (China, Iran, South Korea and Italy) and fit this with the SEIR type model in order to estimate the basic reproduction number R-0 We also discussed the development trend of the disease Our model is quite accurate in predicting the current pattern of the infected population We also performed sensitivity analysis on all the parameters used that are affecting the value of R-0


The invention relates to an identification sensor (1) for a locking system (2) of a motor vehicle (3). The identification sensor is provided with a housing (20) and an illumination member (24) arranged in the inner part (22) of the housing. The housing is provided with at least one operating mechanism (21). The operating mechanism works cooperatively with a switch element (23) arranged in the inner part (22) of the housing in operation. According to the invention, the housing (20) is provided with a frame mechanism (10), an information carrier (30) is arranged in the frame mechanism, and the information carrier is illuminated by illumination member (24).


The raison d'ˆ etre for measuring CP violation in the B system is to test the standard model (SM) [1]. As always, the hope is that we will find evidence for the presence of new physics. There are many signals of new physics, but only a handful are of the " smoking-gun " variety, i.e. they are free of hadronic uncertainties, and hence independent of theoretical input. All of these rely on the measurement of CP-violating rate asymmetries in B decays. They include • B 0 d (t) → ΨK S vs. B 0 d (t) → φK S. Both of these decay modes probe the CP phase β within the SM.


Abstract Diversity, equity and inclusion have become buzz words over the last year. While this is important, it is necessary that library staff do not move on from the vision of these words. Equity, much like the health of a person, is holistic. It is not just having a book club on race issues or celebrating Black History Month; equity is evaluating each aspect of the opportunities and power libraries and library staff possess and continually working toward a place of diversity, inclusion, accessibility, and tools that level the inequities. This paper will show how librarians and health equity fellows proactively carried out an initiative for health equity to support the campus vision, and translated this vision into practical steps that work toward equity for the community they serve. This work included acknowledging shortcomings, locating gift funds, conducting a needs analysis of the collection, providing resources and other services, and offering fellowships for graduated students to perform these duties.


Background: Access to sexual and reproductive health care services for most at risk population (MARPs) is a very important step in stemming the spread of HIV; as HCT and early diagnosis and treatment of STIs can contribute to reduction of the spread of HIV. Within Nigeria and most Sub Saharan African countries, MARPs are highly stigmatized both in the general society and in health care centres. It is important health care facility based facilitators and barriers to MARPs' access to use of sexual and reproductive health care services by MARPs are identified to guide project design and implementation as well as policy formulation.
Methods: Mystery client survey was conducted in thirty three (33) healthcare facilities in Nigeria. For the purpose of the survey, the mystery clients (MARPs) sought only STI consultation and HIV counselling and testing services. Twelve (12) mystery clients visited each facility seeking either STI or HCT service in the facility. Ethical approval was obtained from the Nigeria Institute of Medical Research (NIMR). SPSS version 20 was used for the Bi-variate and multivariate logistic regression analysis.
Results: While positive attitude of health care workers was found to be a facilitator of access to health care services, this study shows that perceived quality of services is a very significant variable in MARPs' use of a health care facility. We also found that MARPs were more willing to refer their community members to facilities that have educational materials promoting non-stigmatizing attitude towards PLWHAs and MARPs. Amazingly, privacy of services provided was not significant.
Conclusion: It is recommended that standard of health care practices should be enforced. Training and re training of health care workers on provision of MARP friendly services should be formalized and scaled up. Investment in educational materials (posters) in health facility settings should be promoted.


Limited information is available on the impact of target disease-modifying anti-rheumatic drugs (tDMARD) on patients with rheumatoid arthritis (RA) and type 2 diabetes mellitus (T2DM).The objective was to compare T2DM-related healthcare resource utilization (HCRU) and cost for TNF inhibitors (TNFi)-naive patients pooled from two commercial databases with RA and T2DM receiving abatacept, other non-TNFi, or TNFi.A retrospective, observational study was conducted with MarketScan and PharMetrics (January 2008-September 2018). The study population included TNFi-naïve adult patients with RA and T2DM newly initiating abatacept, TNFi (adalimumab, certolizumab pegol, etanercept, golimumab, infliximab) or other non-TNFi (tocilizumab, anakinra, sarilumab, rituximab, tofacitinib). Date of tDMARD initiation was the index date. Patients had ≥2 RA diagnoses separated by ≥7 days, ≥1 T2DM diagnosis, and had ≥12 months of pre-index continuous enrollment. Follow-up ended at the end of patient insurance enrollment, study period or index treatment. T2DM-related HCRU and costs including inpatient stay, outpatient visits, ER visits, and pharmacy use were measured on a per-patient-per-month (PPPM) basis (2018 USD). Patients treated with abatacept were matched to TNFi and non-TNFi cohorts separately by propensity score adjusted with patients baseline comorbidities, HCRU, and costs.A total of 16,236 patients meeting criteria were identified. Most patients were female (74.3%), and the overall average age of 55.4 years (Table 1). After matching, 850 pairs of abatacept vs non-TNFi patients, and 1,096 pairs of abatacept vs TNFi patients were included in the adjusted results. Patients initiating abatacept had $144 lower adjusted T2DM-related costs as compared to non-TNFi and $79 lower costs than TNFi cohorts (Table 2).Table 1.Patient CharacteristicsAbataceptn=1,134Non-TNFin=1,353TNFin=13,749TotalN=16,236Age, mean years (SD)58.5 (11.3)57.7 (11.2)54.9 (10.6)55.41 (10.7)Gender, female, n (%)936 (82.5)993 (73.4)10,142 (73.8)12,071 (74.3)CCI, mean (SD)2.2 (1.4)2.3 (1.4)1.8 (1.1)1.89 (1.14)DCSI, n (%) Cardiovascular361 (31.8)406 (30.0)2,500 (18.2)3,267 (20.1) Neuropathy294 (25.9)374 (27.6)3,161 (23.0)3,829 (23.6) Nephropathy146 (12.9)193 (14.3)1,151 (8.4)1,490 (9.2) PVD131 (11.6)155 (11.5)874 (6.4)1,160 (7.1) Retinopathy103 (9.1)119 (8.8)922 (6.7)1,144 (7.0) Cerebrovascular74 (6.5)102 (7.5)620 (4.5)796 (4.9) Metabolic9 (0.8)20 (1.5)141 (1.0)170 (1.0)CCI: Charlson comorbidity index; DCSI: diabetes complications severity index; PVD: peripheral vascular disease.Table 2.Adjusted T2DM-related HCRU and Costs after Propensity Score MatchingAbataceptn=850Non-TNFin=850Diff (ABA- Non-TNF)Abataceptn=1,096TNFin=1,096Diff (ABA- TNF)T2DM-related HCRU (per 1000 Patients per Month)Number of Hospitalizations13.920.4-6.5*12.614.9-2.3*Number ofER Visits22.016.15.9*18.416.32.0*Number ofOutpatient Visits311334.8-23.7*299.3286.912.4T2DM-related Costs (PPPM $)Inpatient Costs507535-28413475-62ER Costs271710*2225-3Outpatient Costs190323-13318617016*Pharmacy Costs1071007*97128-31Total Costs831975-144719798-79**P<0.05TNFi-naive RA patients with T2DM newly initiating abatacept had lower adjusted rates of T2DM-related hospitalizations compared to patients who initiated a non-TNFi or a TNFi. Total costs were lower among patients initiating abatacept vs. patients who initiated a non-TNFi or a TNFi. Findings suggest that initial abatacept among TNFi-naïve patients may be able to reduce healthcare utilization arising from T2DM complications and reduce T2DM-related costs in RA patients.Xue Han Employee of: BMS, Qian Xia Shareholder of: I own shares of Bristol-Myers Squibb Company, Employee of: I am a paid employee of Bristol-Myers Squibb Company, Ying Bao Shareholder of: Bristol-Myers Squibb, Employee of: Bristol-Myers Squibb, Vardhaman PATEL Employee of: Bristol Myers Squibb, Amrina Roy Employee of: Mu-Sigma, Varshini Rajagopalan Employee of: Mu-Sigma, Francis Lobo Shareholder of: Bristol-Myers Squibb (US), Employee of: Bristol-Myers Squibb (US)


Calculations of neutron and gamma-ray fluences from 14-MeV neutron and /sup 252/Cf sources in liquid air and liquid nitrogen have been performed. These calculations were made specifically for comparison with experimental data measured at Stohl, Federal Republic of Germany. The discrete-ordinates method was utilized with neutron and gamma-ray cross sections from ENDF/B-IV. One-dimensional calculational models were developed for the sources and tank. Limited comparisons are made with experimental data.


Phosphate solubilizing microbes (PSM) can improve soil P availability by P dissolution. These microbes can make substances that regulate plant growth, which promotes plant growth. The present study aimed to characterize PSM and determine how PSM application affected P solubilization, soil phosphatase activity, and upland rice yield. The greenhouse experiment used a factorial randomized block design (RBD) with two factors and three replications. The first factor was PSM isolates, which came in four different forms: without microbes, with microbes (Burkholderia sp.), with fungus (Penicillium sp.), and with a combination of microbes (Burkholderia sp. and Penicillium sp.). The PSM isolates were characterized to analyze the production of organic acids, phosphatase enzymes, and phytohormones. The second factor was the superphosphate fertilizer dose, which has four levels: 0, 50, 75, and 100 kg P ha−1. According to the PSM characterization, it produced organic acids such as lactate acid, oxalate acid, citric acid, and acetate acid, as well as phytohormones (IAA) and the enzyme phosphatase. The pot experiment results show that the PSM inoculation raised the available P and soil phosphatase, P content of the plant, decreased soil organic P, and increased upland rice production. For improving available P, phosphatase activity, P content of the plant, and upland rice yields, mixed inoculants of phosphate-solubilizing bacteria and fungi performed better. The availability of soil P, the activity of the enzyme phosphatase, and the upland rice yields were all improved by applying P fertilizer at 75 kg P ha−1. This study showed that PSM as a biofertilizer reduced the dosage of inorganic fertilizers by up to 25%.


Architecture is closely related to human development. Different architectural shapes and texture structures reflect the changes of society and the level of social development. They are not only important materials for studying history but also carry the profound significance of human history. However, due to chemical effects, the acid, alkali, salt, and corrosive solvents are applied and produced in the process of industrial production, as well as the corrosive media contained in the atmosphere, groundwater, surface water, and soil will corrode the ancient buildings. The whole picture of many ancient buildings cannot be completely preserved, let alone used as research materials to deeply explore history and humanities. With the development of computer science and technology, we hope to protect and repair traditional ancient buildings through modern technology, which not only respects the long history of the Chinese nation but also helps us better study history through ancient buildings. This paper takes the ancient buildings of traditional villages in Guanzhong, Shanxi Province as an example, optimizes them on the basis of predecessors, and explores the protection and restoration of ancient buildings based on the improved priority algorithm. The results show that the proposed algorithm performs better in the protection and restoration model of ancient buildings than the traditional algorithm.


the rise in usage of Facebook, Myspace, Twitter, blogs, forums and other online means of communication has created a digital landscape where people are able to post their opinions or socialize through a variety of means and applications. Analyzing these online postings using sentiment analysis algorithms facilitates a general overview about different matters. As sentiment analysis is the computational study of opinions, evaluations, attitudes and emotions expressed by people in their posts. We have applied Naïve Bayes, Multinomial Naïve Bayes, Bernoulli Naïve Bayes, Logistic Regression and Linear Support Vector classifiers on training dataset gathered from online postings. The datasets are already labelled for negative or positive texts and with the help of Bag-of-words and TF-IDF methods we have conducted the feature extraction from the texts of each type and trained the above classifiers on those particular features. Our study shows that the classifiers perform differently depending on the training data, and the increase in the dataset size will improve their accuracy, as well as ascertains a general trend about people's opinion on a particular subject.


The standard of care for breast cancer patients includes treatment with chemotherapy, antiestrogens, and targeted inhibitors. There are more than 100 drugs approved to treat breast cancers with more in the pipeline of discovery and approval; however, few biomarkers have been identified for individualized, patient-specific treatment planning. Currently, drug regimens are chosen based on the presence or absence of specific receptors, including progesterone receptor (PR), estrogen receptor (ER), and human epidermal growth factor receptor 2 (HER2) and patient response is assessed by changes in tumor size weeks after treatment. Unfortunately, many patients do not initially respond to therapy or develop a resistance, and face a greater risk of recurrence and death. Herein we present a novel, light-based technology that can accurately predict individual tumor response to anti-cancer drugs based on drug-induced changes in metabolism. Cellular metabolism is a powerful indicator response to treatment, because the oncogenic drivers targeted by therapeutic agents often regulate cellular metabolism. In this study, we demonstrate the sensitivity of optical metabolic imaging to predict therapeutic response in xenografts in vivo, and in primary tumor derived organoids. Optical metabolic imaging utilizes mulitphoton fluorescence intensity and fluorescence lifetime imaging to probe the concentrations and protein-binding dynamics of cellular NADH and FAD, two coenzymes of metabolism. A composite endpoint, the OMI index, provides a robust, dynamic readout of cellular metabolism. First, we probed metabolic changes within ER+/HER2+ tumors treated with trastuzumab, an anti-HER2 antibody. After 48h of a single injection of trastuzumab (HER2 antibody), the OMI index of responsive tumors (ER+/HER2+) decreased (p Citation Format: Alex J Walsh, Rebecca S Cook, Melinda E Sanders, Carlos L Arteaga, Melissa C Skala. Optical metabolic imaging predicts therapeutic response in breast cancer tumors and organoids [abstract]. In: Proceedings of the Thirty-Seventh Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2014 Dec 9-13; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2015;75(9 Suppl):Abstract nr P3-06-38.


In the united states, cost-sharing in health insurance coverage has become the primary mechanism for reducing insurance expenditures and, by extension, maintaining affordable coverage. Cost-sharing involves patients making various out-of-pocket (OOP) payments for their own health care aside from whatever the insurer pays. As a patient's spending on health care grows month by month in any given year of coverage, she moves through three different "zones" of insurance, from no insurance, to partial insurance, and finally to full insurance. Looking at these zones individually:


The most important quantity in infectious disease epidemiology is the basic reproduction number (R 0). R 0 is the expected value of the number of infections per unit time. This paper aims to model the spread of COVID-19 in Indonesia using the multi-state SIRD model and then determine the transition intensities to construct R 0. The estimation of the transition intensity uses the maximum likelihood approach with the assumption of a homogeneous time Markov chain with an exponential distribution of transition intensity and the number of transitions in a Poisson distribution. The results of the transition intensity estimation are used to construct R 0 with the next generation matrix method. From the multi-state SIRD model, the largest transition is shown in the individual healing process, namely the movement from an infected to susceptible state, while the smallest transition is the transition from susceptible to dead. The R 0 obtained is 1.079708 (> 1) meaning that the number of individuals infected with COVID-19 will increase until it reaches a stable point. Transition intensities is an effective way of determining R 0 where the dynamics of disease transmission depends on the number of individuals transition between states and the total waiting time in a certain state. R 0 > 1 states that the COVID-19 pandemic in Indonesia has not been over yet.


A comprehensive kinetic model based on the method of moments is developed for understanding the kinetics of activators regenerated by electron transfer atom transfer radical polymerization (ARGET ATRP) under microwave irradiation. Both the experimental data and the simulation results show that the polymerization under microwave irradiation is much faster than the thermal polymerization. Simulation results indicate that the acceleration of polymerization can be attributed to the increase of propagation rate coefficient and the radical generation by microwave irradiation. Kinetic behaviors, such as the effect of catalyst concentration and initial initiator, are investigated in detail. Results show that the catalyst concentration has negligible influence on polymerization rate while the initiator concentration can affect both the molecular weight and the reaction rate. In conclusion, this work thoroughly investigates the kinetic mechanism of ARGET ATRP under microwave irradiation, providing both theoretic and experimental supports to improve the product property of polymer materials.


The pulp and paper industry relies heavily on electricity as an energy source. Although a major share of the pulp and paper industry's electrical needs are met by cogeneration, a significant bottom line impact on mill production costs. Some utilities now have a new and innovation pricing methodology that provides cost benefits to their pulp and paper customers while also allowing utilities to achieve their own load management goals. This pricing concept is based on a utility's marginal cost structure, and is generally known as real-time pricing (RTP). Application : this paper provides an explanation of the RTP concept for purchased electricity. An actual pulp and paper mill's perspectives and experiences with RTP are presented from the stand-point of mill operations and the economic benefit of this innovative rate structure.


The conclusion of the book opens with an Iraqi epilogue on the ways in which paramilitarism has been a prominent feature of state-building in postcolonial Iraq, especially after the US invasion of 2003, when militias became a daily fact of life. The chapter discusses the latest incarnation of paramilitarism in Iraq, the Popular Mobilization Forces (al-Hashd al-Shaabi), which mobilized against the Islamic State in 2014 and became immensely powerful, and shows that paramilitarism is here to stay. The chapter continues with a theoretical wrap-up of paramilitarism and state formation, and finally comments on the future of paramilitarism and the challenges it poses to international order and security.


We investigate the performance of a fast reconstruction algorithm based a Backpropagation algorithm for 3D Microwave Imaging of Body Part Anomalies.


Although it has been shown that the rises in cortical activities by 3 and 5/sec flash stimulations verified in the frequency response of the visual cortex of unanesthetized rabbits (MIMURA and SATO, 1965) can be correlated with the excitability changes of 5/sec (BIsHOP, 1933) or 4-5/sec (PEARLMAN, 1963) in the visual cortex of the rabbit, it was not ascertained whether these excitability changes originated from the cortex itself or from subcortical structures nor was it ascertained whether it was from the specific or the nonspecific system. The present study is an attempt to solve the above problems through observations on the pattern of response to repetitive flash stimulations in the specific and non-specific systems of the cortex and subcortical structures of anesthetized and unanesthetized rabbits.


Abstract The effect of the sweep velocity of an applied magnetic field on the magnetization behaviour of ferromagnetic polycrystalline nickel is theoretically interpreted on the basis of the linear anelastic mechanical model of Voigt. The experimentally observed creep magnetization using a step field and the magnetization time lag using a sweep field are thus interconnected. On the basis of these results, a loopless anhysteretic magnetization and demagnetization curve of a ferromagnetic material is predicted and discussed.


cw and time-resolved photoluminescence spectroscopy is used to study ZnSe/${\mathrm{Zn}}_{1\mathrm{\ensuremath{-}}\mathit{x}}$${\mathrm{Mn}}_{\mathit{x}}$Se quantum wells with semimagnetic barriers in an external magnetic field. The data demonstrate a change of the dominant energy relaxation mechanism from disorder localization of light-hole excitons at zero-field to heavy-hole exciton interface magnetic polaron formation at intermediate fields and, again, disorder localization of heavy-hole excitons at large magnetic fields. The formation of the interface magnetic polaron is promoted by a magnetic-field-induced type-I\char21{}type-II transition for heavy-hole excitons. Despite the transition, neither the exciton lifetime nor its optical oscillator strength is dramatically altered. This is, as we confirm by numerical solution of the two-particle Schr\"odinger equation, a result of the electron-hole Coulomb interaction. The polaron formation time is initially 110 ps, but decreases with growing magnetic field down to 70 ps (B=5 T). A theoretical investigation of the polaron formation dynamics shows that the associated change of the exciton wave function is smaller, the closer the ${\mathrm{Mn}}^{2+}$ spin system is driven into saturation by the external field. As a consequence, the polaron formation time approaches the characteristic ${\mathrm{Mn}}^{2+}$ spin response time. Our measurement uncovers a fast primary localization prior to the polaron process\char22{}but also of magnetic origin\char22{}that we believe to be necessary to start the polaron formation. \textcopyright{} 1996 The American Physical Society.


We will demonstrate products of the BitCurator NLP project, which is developing software for LAMs to extract and expose features (e.g. people, places, organizations, events, relationships, topics) in text extracted from born-digital materials. The services and methods can be used by LAM professionals for appraisal and description, as well as facilitating a wider range of access and use scenarios.


Having an advantage of being the majority in Indonesia makes the Islamic ideologies particularly the ideology of Islamic Khilafah spreads easily amongs the Indonesian moeslim. Furthermore, those who believe in the ideology of Islamic Khilafah also believe that this ideology is the solution to the problem of the nation such as poverty, unemployement, amorality etc. Historically, the concept of Islamic Khilafah tells that a secular nation is unacceptable and the nation of the Islamic Khilafah is the absolute answer to that. This article elaborates the value of the Islamic notions proposed by Islamic sholars, formal instutions or even Hizbu Tahrir then compares them to the value of Pancasila. In this article, I compare many references regarding Islamism, Khilafatism, and Pancasilaism, and then present them in a critical narration. In short, the optimism to the value of Pancasila rises due to the fact that Islam is apparently one of the foundations of Pancasila. In the other hand, I reckon that the ideology of Islamic Khilafah is a failed product due to its nature of violence and absoluteness which make the ideology and the followers stuck in their comfort zone and their claim of righteousness.


AIM To investigate the role of brain gut peptides in the electro acupuncture regulated neuroendocrine immune network as well as its mechanism. METHODS The rats were randomized into 5 groups, including the control, the Tsusanli , the immunosuppressive model, the non acupoint group, and the Tsusanli +immunosuppressive groups. The Tsusanli group rats, fixed, were electro acupunctured at Tsusanli (He Sea Point, St 36) on both sides continually for 30 min at any point between 07:00 and 09:00 for 7 d on a daily basis. The location of the acupoints for EA: Tsusanli (He Sea Point, St 36) was identified at approximately 5 mm below the small end of the fibula on the outer lower side of knee joint hind limb of the rats and the non acupoint was 0.5 cm beyond Tsusanli . Changes in substance P (SP) and vasoactive intestinal peptide (VIP) contents in the pituitary gland and peripheral blood were determined by radioimmunoassay. T lymphocytic subgroups were assayed to reflect the cellular immunity. Erythrocytic immunity was assayed by red blood cell C 3b receptor rosette (RBC C 3b RR) and red blood cell immune complexes rosette (RBC ICR). RESULTS After EA, the immuno adhesiveness of T lymphocytic subgroups and erythrocytes of both healthy rats and immuno suppressive rats was enhanced. What is more, the values of SP and VIP in rat pituitary gland and peripheral blood increased signifi cantly in comparison with that of the control and were positively correlated with the change in CD 4 +. There was no significant difference between the indexes of the non acupoint group and that of the control. CONCLUSION EA at Tsusanli can positively regulate the T lymphocytic immunity and erythrocytic immuno adhesiveness in the peripheral blood of both normal and immuno suppressive groups of rats. When the immune system is regulated by EA at Tsusanli , the contents of SP and VIP in the central and peripheral blood are positively correlated with the change in the immune system, indicating that SP and VIP have an important role in the EA regulation of the neuroendocrine immune network. The results of our study, consistent with previous findings in the field, make an important complement to the regulatory effects of EA on the immune system.


In my first weeks as the editor of The Journal of School Nursing, I have had the privilege of reading and reviewing exciting research studies and quality improvement projects that have the potential to significantly improve student outcomes. At the same time, I read many manuscripts that describe research and scholarly projects that do not add to school nursing science. School nursing is fortunate to have dedicated and accomplished researchers who are devoting their careers to building the knowledge and evidence for practice. Many others are embarking on their first scholarly endeavor. No matter how limited, research and program evaluations require valuable time, materials, and internal and external partners. Novice investigators or new clinical implementation leaders can invest those limited resources into building on the science that supports student health. Every year, the National Association of School Nurses publishes research priorities for school nursing. The 2020– 2021 NASN Research Priorities (2020) are:


With the iterative update of media technology, after a series of rapid growth cycles, the media platform of short video is not difficult to find that the short video industry is gradually changing from the previous traffic competition to the era of "content is king".It is not hard to see that in fact, users on short video platform may have aesthetic fatigue for ordinary online red, but the Internet celebrity for the elderly is refreshing and completely caters to the curiosity psychology of short video platform users. And according to the survey of media use of the elderly, we can find that: with the increase of the number of middle-aged and elderly people surfing the Internet, the new media platform is no longer just a gathering place for young people, and the scope of online red should not only be limited to the young online red. From the perspective of short video platform as a whole, the commercial implantation of short video content is gradually deepening. The massive and fragmented User-created Content of each platform is in opposition to the large-scale demand of advertising, and it can not meet the continuous demand of the platform for high-quality resources. The emergence of Multi-Channel Network has greatly improved the content production efficiency, and it has become a professional content production support organization, playing a role of economic support The role of economy and business. According to the first mock exam, most of the old red nets are also out of the Multi-Channel Network business model. The advantage of Multi-Channel Network is that it can not only achieve mass production in production content, but also realize the industrialization and industrialization of the network redactor training strategy. Created a large number of high-quality elderly web celebrity short video content creators, also led the new short video platform to create web celebrity business model.


A fluorescent airborne stratospheric hygrometer (FLASH) for precise water vapor measurements on board a high-altitude airplane in the upper troposphere and the lower stratosphere has been developed and produced at the Central Aerological Observatory. The range of measured water vapor concentrations is 0.5- 300 ppmv at altitudes of 8-21 km. The results of laboratory tests of the instrument are compared to the data of the other hygrometers. Some results of water vapor measurements on board the Geofizika M55 high-altitude airplane in different regions of the Earth are presented.


The statistically inspired modification of the partial least squares (SIMPLS) is the most commonly used algorithm to solve a partial least squares regression problem when the number of explanatory variables (<inline-formula> <tex-math notation="LaTeX">$p$ </tex-math></inline-formula>) is larger than the sample size (<inline-formula> <tex-math notation="LaTeX">$n$ </tex-math></inline-formula>). Nonetheless, in the presence of irregular points (outliers), this method is no longer efficient. Therefore, the robust iteratively reweighted SIMPLS (RWSIMPLS), which is an improvement of the SIMPLS algorithm, is put forward to remedy this problem. However, the RWSIMPLS is still not very efficient with regard to its parameter estimations and outlier diagnostics. It also suffers from long computational times. This paper proposes a new robust SIMPLS that incorporates a new weight function constructed from <italic>nu</italic>-Support Vector Regression in its establishment. We call this method the robust iteratively reweighted SIMPLS based on <italic>nu</italic>-Support Vector Regression, denoted as SVR-RWSIMPLS. To avoid misclassification of observations, a new diagnostic plot is proposed to classify observations into regular observations, vertical outliers, good (GLPs) and bad leverage points (BLPs). The numerical results clearly indicate that the SVR-RWSIMPLS is more efficient, more robust and has less computational running times than the RWSIMPLS when multiple leverage points and vertical outliers exist. The proposed diagnostic plot is also very successful in classifying observations into correct groups.


Using a case of the closing of localisation (mainly for prostitution activities) in Km. 17 Balikpapan, this paper describes and maps out debates on religious and secular logics in a democratic society. This paper applies sociology of politics approach as a perspective to analyze the phenomenon. Furthermore, this paper is guided by the theory of public reasoning echoed by John Rawls and Abdullahi Ahmed an-Na'im. Results show that in dealing with social phenomena people mainly use religious reasoning. Pioneered by a number of Islamic organizations hitting down the street, soon these turn into protest movement in a convergent manner. These typical religious acts are quite far from promoting win-win solutions. Hence, it is difficult to make a range of appropriate, clear, and systematic public policies concerning the phenomena. Keywords: religious and secular reasoning, theory of public reasoning, and protest movement.


This paper empirically examines the roles of various governance mechanisms in different corporate cultures. The evidence shows that, in manipulative firms sued for financial scandals, more independent boards do not increase the likelihood of CEO replacement following the discovery of alleged scandals. However, higher levels of bank loans and highly concentrated outside blockholdings increase the likelihood and lead to more prompt CEO dismissal. In normal firms without financial scandals, board independence increases CEO turnover and the presence of blockholders and bank borrowing has no effect. These findings suggest that there is no need to regulate board structure; normal firms will rely on internal governance and outside investors only serve as providers of funds. However, in manipulative firms, board independence can be fabricated, thus the main source of discipline comes from outside investors. Imposing requirements on board independence may unintentionally reduce information available to outsiders because firms cannot self-select into different board structures that may attract sophisticated investors with different appetites for resolving agency problems.


The paper proposes a method in which the construction of the variable geometry suspension system and the design of robust suspension control are performed simultaneously in order to enhance vehicle stability. In the control scheme a predefined road trajectory required by the driver with a steering command is followed to carry out various maneuvers. The variable geometry suspension system provides the modification of the mechanical geometry efficiently. During maneuvers an autonomous control system influences the camber angles of the rear wheels by using a variable geometry suspension system. The control system must guarantee various crucial vehicle performances such as trajectory tracking, roll stability and geometry limits. Since there is an interaction between the construction design and the control design a balance must be achieved between them.


Part One: Board Membership in Perspective. 1. On Joining a Board. 2. The Qualities of a Good Board Member. 3. What You Should Know About the Law Governing Nonprofits. 4. A Nonprofit Is Not a Business. Part Two: Board Member Responsibilities. 5. Your Role as a Board Member. 6. AttAndance at Board Meetings. 7. Strategic Planning and the Mission. 8. Choosing and Evaluating the Chief Executive. 9. Assuring Financial Responsibility. 10. Supporting and Overseeing Programs. 11. Participating in Fundraising. 12. Keeping the Board Effective. Part Three: Board Members and Boards. 13. Board Procedures and Organization. 14. Rights, Obligations, and Liabilities of Board Members. Conclusion: Leadership: Every Board Member Has a Role. Resources A: A Donor Bill of Rights. Resources B: The Council of Better Business Bureaus' Standards for Charitable Solicitation. Resources C: National Charities Information Bureau's Standards in Philanthropy.


To study the mechanism of adhesion of Lactobacillus plantarum STⅢ on Caco-2 cells,the adhesive ability of the bacterial cell to the mammal cells was investigated by fluorescence labeling with CFDA-SE and the components on the cell surface involved in the adhesion were extracted.After treatments by chemicals and enzymes,it was shown that pepsin,trypsin,LiCl,phenol,guanidine hydrochloride and heat treatment could signigfantly decrease the adhesive ability of ST-Ⅲ ,indicating that the S-layer protein or lipoteichoic acid may be related to the adhesion of STⅢ to Caco-2 cells.The suppressive test and reversible binding test confirmed that the S-layer protein mediated the adhesion process,whereas the lipoteichoic acid on the bacterial cell surface did not participated in the adhesion.The results showed that the crude surface protein extracts of ST-Ⅲ might contain S-layer protein which participated in the adhesion.The SDS-PAGE assay showed that the crude extracts was composed of three proteins with molecular weight of 72.7 kD,34.1 kD and 24.3 kD respectively.


In recent years, information systems are essential to decide management for an enterprise. In the information systems of an enterprise, one management problem is that cost of maintenance processes for the information system become larger than the development process of the information system itself. As one cause of this management problem, there are many inquiries in the initial failure period after operating the information system. In general, there are many times to correspond to many inquiries because the inquiries are not able to forecasted. In previous studies, there have been some studies regarding factors that lead to the occurrence of inquiries, but these factors have not been clarified. In this paper, factors of the inquiries that occur are estimated by cluster analyzing contents data, time and the number of cases of bugs. From this estimation, a forecasting model that includes inquiries of bugs occurring is proposed. Moreover, information sheets are proposed to introduce the proposed forecasting model to the development field of information systems.


SummaryValeriana glechomifolia is an endemic species of southern Brazil, capable of accumulating, in all of its organs, the terpene derivatives known as valepotriates, the presumed sedative components of the roots of pharmaceutically used species of Valeriana. In vitro cultures of the plant were established and the accumulation of acevaltrate, didrovaltrate, and valtrate in callus, cell suspension, and untransformed root cultures was studied. Leaves of in natura plants and roots of micropropagated plantlets were used as the explants for callus induction and root culture establishment, respectively, on Gamborg B5 basal medium supplemented with 2,4-dichlorophenoxyacetic acid (2,4-D) alone or with kinetin (KIN). Culture growth and secondary metabolite yields were enhanced with 2,4-D (4.52μM) and KIN (0.93μM). Maximum valepotriate contents, quantified by HPLC, of acevaltrate (ACE) 2.6mg g−1 DW, valtrate (VAL) 10.2mgg−1 DW, and didrovaltrate (DID) 2.9mg g−1 DW were observed in root cultures after 7–8wk of culture.


Abstract The typical business processes in building material equipment manufacturing enterprises are analyzed, and the framework and functional models of the tracking system for building material equipment manufacturing enterprises in the order lifecycle are presented. Based on the model, using a mobile agent and XML technology, the order tracking system's framework is built for building material equipment manufacturing enterprises based on a mobile agent in the Aglet platform. The key technologies in the process of tracking the order lifecycle are introduced in detail. Finally, a prototype system is developed and used in an enterprise successfully, verifying the feasibility and availability of the system.


The purpose of this study was to evaluate the histologic change of the inferior alveolar nerve according to distraction amount following mandibular lengthening. Seven rabbits weighing about 2 kg were used. Corticotomy was performed on the mandibular body anterior to the right first premolar region and unilateral external fixation device was placed. Every effort was made to preserve the inferior alveolar nerve during the corticotomy. The rabbits were then allowed to heal for 7 days without distraction of the device. The mandible was lengthened 0.36 mm/day, 0.76 mm/day, or 1.0 mm/day. Corticotomy and lengthening of mandible were not performed in control group. After the completion of the lengthening process, a 14-day-consolidation period was allowed. After consolidation, rabbits were sacrificed, and histologic examination of the inferior alveolar nerve was performed. The results obtained were as follows: 1. In the control group, normal trifascicular pattern of inferior alveolar nerve was observed. Epineurium, perineurium, endoneurium, and axon with myelin sheath were observed in normal appearance. 2. In 0.36 mm/day distraction group, the trifascicular pattern was normally shown, and there was no destruction in epineurium, perineurium, and endoneurium. The mild changes including myelin attenuation, axoplasmic swelling and darkening were observed. 3. In 0.72 mm/day distraction group, it was possible to differentiate the epineurium from the perineurium. Two normal fascicles and one injuried fascicle were observed with a partially destructed perineurium. Most of the axons had axoplasmic swelling and darkening. 4. In 1 mm/day distraction group, it was difficult to differentiate the nerve structures such as fascicles, epineurium, perineurium, and endoneurium. The axons were severely destroyed, except few which showed decreases in size and changes in shape. Some collagen matrices were observed around the axons. These results suggest that the higher the distraction amount, the more severe the injury to the inferior alveolar nerve, fascicles, axons. Although distraction osteogenesis may be useful, the amount of distraction should be carefully selected.


The purpose of this study is to propose a simulation model to predict the occurrence of defects over time. This simulation model estimates the total amount of defects and the amount of individual defects according to the characteristics of the target building based on past similar cases. It is considered that the prediction of the occurrence of defects over time, which is the result of this model, can be utilized throughout the life cycle of buildings. Especially, it can be used as a key indicator to prevent defects or to establish appropriate management level in the design stage. According to the results obtained by applying the proposed model, it is necessary to reflect the management level of the building and to supplement the defect related data. Therefore, further studies on the above-mentioned additional items will be needed to be practically used in the proposed model.


This paper outlines one method through which learner self-regulation can be promoted in CEFR-informed courses using a learning cycle. Previous reports of learning cycles in use have not adequately described how they can be operationalised within the classroom—typically, they have been limited to descriptions of the cycle alone. This paper provides specific examples of how a CEFR-informed learning cycle has been implemented in an EFL process writing class. Cyclical learning and the CEFR as the tools for bringing learner selfregulation practices forward are first introduced. Next, a description of selfregulation practices in the classroom context using the example of an essay writing task in a process writing class is provided. The discussion then focuses on how instructors can encourage learners to carry their self-regulation practices forward to their future learning once a class has been completed. We conclude by suggesting possible benefits of this learning approach, and future directions for research.


Japan is a nation which is highly dependent on the import of raw materials to supply its manufacturing industry, notable among them copper. When extracting copper from ore, a large amount of energy is required, typically leading to high levels of CO2 emissions due to the fossil fuel-dominated energy mix. Moreover, maintaining security of raw material supply is difficult if imports are the only source utilized. This study examines the environmental and economic impacts of domestic mineral production from the recycling of end-of-life products and deep ocean mining as strategies to reduce CO2 emissions and enhance security of raw material supplies. The results indicate that under the given assumptions, recycling, which is typically considered to be less CO2 intensive, produces higher domestic emissions than current copper processing, although across the whole supply chain shows promise. As the total quantity of domestic resources from deep ocean ores are much smaller than the potential from recycling, it is possible that recycling could become a mainstream supply alternative, while deep ocean mining is more likely to be a niche supply source. Implications of a progressively aging society and flow-on impacts for the recycling sector are discussed.


Poor stability of hole wall in gas drainage of soft coal seam often causes problems such as hole injection and collapse, difficult screen pipe putting down, and poor drainage rate. The paper introduces the equipment and process of the technology and industrial experiment conducted in Zhangchun Mine. The results show that the pore formation rate of the screen pipe putting down along full length borehole is 50% higher than the traditional method. In addition, the gas extraction concentration of a single hole increases by 2.8 times and the gas flow increases by 2 times. Besides, the effect of hole-protection is far better than the traditional process, which could increase the drainage efficiency greatly in the soft coal seam.


Among the international relationships at present,strategtic associate relationships are increasing and diversiform.They are different from each other,each one emphasized in distinct aspects.We should cherish the Sino-Russia strategtic associate relationship because it is hard-earned.Neither can we over-estimate this relationship,nor consider it immanence——it includes everything,of course we also can not debase it and take it for granded.Sino-Russia stragetic associate relationship has some distinct characteristics while others do not.When variables appear,both sides should not be a storm in a teacup,but deal with it calmly and intellectly.In course of affiliating with foreigners,we should not blame everyone and everything when difficulty appears,on the country we should summarize the experience and improve the replying variable ability.


Computational linguistics is a subject closely related to contemporary science and technology. The research results of computational linguistics have been applied in machine translation, information retrieval, natural language man-machine interface, and other important fields. At the same time, with the development of machine translation, problems have also emerged. This paper find out some deficiencies of machine translation and post-editing strategies from the comparison between Youdao translation and manual translation of Report on the Work of the Government 2021. Machine translation is ultimately a linguistic problem. In post-editing, translators should pay attention to context, logical relationships, fourword phrases, and so on.


Volume 1 - statistical information on merger activity in the EC barriers to a company's acquisition process, the impact of EC legislation volumes 2 and 3 - detailed breakdowns of the barriers in EC member states, with chapters devoted to each continental country practical information on how acquisitions are made in each member state.


An inductive measurement method was adopted to analyze the magnetic properties of magnetite nanopowders and the possibility to prepare samples having the same geometry is discussed from a macroscopic point of view. The influence of the chemical composition on magnetic and morphological characteristics of the samples was investigated by several measurement techniques with the aim to better investigate the observed magnetic effects. An innovative green Micro-Wave (MW)-assisted approach was used for the synthesis of magnetite (Fe3O4) nanopowder and of magnetic bimetallic systems M@Fe3O4 (M: Ru or Pd) and the effect of noble metals was observed. The structure and chemical identification of the synthesized materials were analyzed and correlated to the measured magnetic properties.


DOI: 10.26650/electrica.2018.73966 Offshore wind farms inherently need alternating current (AC) grid connection with undersea cables. However, this requires reactive power compensation, which is costly and not practical. Moreover, it threads the stability of the system. For these reasons, high voltage direct current (HVDC) transmission is a promising solution since no reactive power is needed. Furthermore, the DC power flow between offshore and onshore locations as well as the reactive power at either side can easily be controlled by voltage source converters (VSCs). In this paper, the modeling and control of an offshore wind farm connected to the mainland grid power with HVDC transmission is proposed. A control strategy is proposed to control active and reactive power at the offshore wind farm converter and DC voltage at the onshore converter. The overall system, including wind farm, offshore and onshore converters, HVDC transmission, and AC grid side, were tested and verified in a simulation environment. The designed control systems of the VSCs were tested by various case studies.


The tumor microenvironment and genomic landscape of intermediate and high-risk primary localized prostate cancers are clinically heterogeneous and result in variable treatment response in individuals. Cancer-specific alterations at DNA and RNA level is a critical driver of intra-tumoral heterogeneity that significantly impacts the molecular processes which influence the path of disease progression and outcome. In this study, we have performed genomic and transcriptomic analysis of 267 primary prostate cancer. Our analysis revealed actionable alterations and gene signatures for risk stratification and decision support. Clinically significant variants were detected in DNA repair (HR and Mismatch pathway), PI3/AKT, and TP53 signaling pathways with a strong association with disease progression. Further, single-cell analysis (scRNA-seq) of prostate cancer that progressed to metastasis post-therapy identified the unique tumor and immune cell-clusters. Functional annotation of these clusters and drug repurposing studies revealed novel targets for therapeutic intervention that was validated using organoid cultures. Our studies show that an Integrated analysis using genomic, clinical, and pathological features has the potential to define prostate cancer subtypes or phenotypes associated with poor prognosis. Our approach can advance prostate cancer treatment in patients with adverse clinical features by providing treatment options beyond the standard of care (surgery or radiation) and with better therapeutic benefit. Citation Format: Dimple Chakravarty, Zichen Wang, Michael Rossi, Parita Ratnani, Boris Reva, Dmitry Rykunov, Kamala Bhatt, Vinayak Wagaskar, Rachel Weil, Kristin Beaumont, Michael Beaumont, Avi Maayan, Robert Sebra, Nina Bhardwaj, Sujit S. Nair, Ashutosh K. Tewari. Genomic and transcriptomic profiles of primary prostate cancer identify unique targets for therapeutic intervention [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 1313.


Sebaceous glands have been reported as components of both normal salivary glands and neoplasms thereof. Primary sebaceous gland tumors occasionally arise within the major salivary glands. We report here a case of an intra‐oral sebaceous gland tumor which appears to have arisen from the parotid duct.


Owing to the economical loses of manufacturing and production industries because of inadequate wear leads to the path way of current study. Moreover, improvements in mechanical properties are equally responsible in order to achieve higher production ability and manufacturability. Current study is a critical analysis of numerous advanced material regarding their mechanical and wear properties. Advanced wear resistance material defines their properties with different reinforcing agents. Effect on the mechanical and wear properties due to different reinforcement phases are analysed in this paper. Improve the mechanical properties of aluminium, grapheme, VN alloy and different thermoplastics through various coating. Effect on the wear rate and wear resistance due to several factors like sliding velocity, sliding time and load factor. Wear rate has a considerable effect in the life of machine tools and also enhance the manufactured product quality.


4 Mohamed Moktar Elsayed Hafeza Introduction ental implant treatment in medically compromised patient stills a point of conflict. According to Diz et al. (2013), there are very limited absolute contraindications for dental implant treatment, but some medical conditions have an increased risk of treatment failure or increased risk of peri-operative complications. (1) One of these conditions is diabetes mellitus. (1) Diabetes mellitus is the most common endocrinal disease. For well-controlled diabetics, implant success is comparable to that of healthy individuals. Also, peri-implant condition is normal and peri-implant bone resorption is comparable to controls. (2) (3) (4) (5) (6) (7) (8) While, for uncontrolled diabetic patients, there is an increased risk of peri-implantitis. (7) (9) However, several studies did not reveal such an impact. (10)(11)(12)


Recent work on voting behavior and political attitudes has established the relevance of anti-intellectual (Merkley, E. (2020). Anti-intellectualism, populism, and motivated resistance to expert consensus. Public Opinion Quarterly, 84(1), 24–48. doi: 10.1093/poq/nfz053; Motta, M. (2018a). The dynamics and political implications of anti-intellectualism in the United States. American Politics Research, 46(3), 465–498. doi: 10.1177/1532673X17719507; Motta, M. (2018b). The polarizing effect of the March for Science on attitudes toward scientists. PS, Political Science & Politics, 51(4), 782. doi: 10.1017/S1049096518000938), anti-science (Mede, N. G., & Schäfer, M. S. (2020). Science-related populism: Conceptualizing populist demands toward science. Public Understanding of Science, 29(5), 473–491. doi: 10.1177/0963662520924259; Rekker, R. (2021). The nature and origins of political polarization over science. Public Understanding of Science, 30(4), 352–368. doi: 10.1177%2F0963662521989193) and anti-expertise (Brewer, M. D. (2016). Populism in American politics. The Forum, 14, 249–264. doi: 10.1515/for-2016-0021; Oliver, J. E., & Rahn, W. M. (2016). Rise of the Trumpenvolk: Populism in the 2016 Election. The ANNALS of the American Academy of Political and Social Science, 667(1), 189–206. doi: 10.1177/0002716216662639) attitudes in politics. However, the increasing relevance of anti-expertise attitudes raises a paradox, as one of the most well-established claims of the persuasion literature concerns the influence of expert sources on attitudes (O'Keefe, D. J. (2016). Persuasion: Theory and research. (3rd ed.) SAGE Publications, Inc.; Pornpitakpan, C. (2004). The persuasiveness of source credibility: A critical review of five decades' evidence. Journal of Applied Social Psychology, 34, 243–281. doi: 10.1111/j.1559-1816.2004.tb02547.x). The current paper explores the influence of messages based on public and expert consensus, as well as the interaction of these messages with expressed mistrust of experts relative to the public. The issue we explore concerns environmental regulations relating to water, an issue on which partisan elites are divided, but one that has not played a highly salient role in recent political discourse. We find that mistrust of experts is negatively related to support for these regulations, as expected, but that, contrary to prior research, increases in mistrust of experts in fact enhanced the impact of the expert message. We discuss potential explanations for why this pattern of results differs from prior work.


For managing product development process of industrial enterprise in effect,method of constructing process model based on ProA modeling unit is put forward based on applying IDEF0,hierarchy Petri nets,object-oriented and analyzing relationship between activity and process.Mathematics modeling of ProA are defined in detail.Definition of ProA,decomposition of input/output,typical operating example of ProA modeling unit and product development process modeling steps are deeply discussed.Ultimately,application research to the mechatronics product development modeling is given to prove the effectiveness.


Wood drying kiln is essentially an enclosed space where air velocity, temperature and humidity are controlled. An experimental study is performed to describe the heat and mass transfer process in drying of wood using kiln. Experiments are conducted in a kiln dryer using rectangular shaped of wood for drying air temperatures of 50, 60, 70 and 75 o C, drying air velocities 1, 1.5, 2 and 3 m/s and wood thickness of 1, 2, 4 and 6 mm. In addition to, effect of sample types [hardwood (red oak) and softwood (beech pine and poplar)] are used. The test rig of the present work has been examined and the obtained results are in a good agreement with available data in the previous works. The obtained experimental results of the present study are found in good trends with the corresponding previous results. Experimental results show that the drying rate increase with the increasing of drying air temperature and drying air velocity but it decrease with the increasing of thickness. Also, it is found that the softwood is dry faster than the hardwood.


C health centers (CHCs) represent the largest system for primary care to poor and undeserved patients in the U.S. Since Jack Geiger and Count Gibson founded the first CHC, Columbia Point Health Center in Boston in 1965,1 CHCs have proven remarkably resilient and effective. For half a century, they have weathered, seven economic recessions, nine U.S. Presidents, federal government shut downs, and sequestrations, and the rise and fall of managed care. In the face of these historic challenges CHCs have provided high quality care while minimizing health care disparities and costs.2– 6 In an era of gigantic health care systems, independently operated CHCs are the little engines that could. Their patient governing boards, community focus, diverse staff and provision of high quality, patientcentered, efficient and equitable care represent a model for the U.S. health system. CHC's success likely reflects their grass roots governing structures, savvy leadership, passionate commitment to care for the underserved and community health, unique payment structures, and support through the National Health Service Corps and various state loan repayment programs.7– 10 Throughout their history, CHCs have received almost continuous bipartisan support in Congress, from both red and blue states. This support has enabled remarkable growth over five decades to more than 1,200 CHCs serving some 23 million low income patients. While FQHC have survived against the odds, they often generate narrow financial operating margins and limited cash reserves.11 Among CHCs, there is wide variation in fiscal health.11 The rapidly changing landscape of health care reform in the United States poses important opportunities and unique threats to CHCs.12 Wright et al report results from a survey of CHC executive directors in Iowa regarding CHC capacity and demands and organizational readiness for change. Nearly three out of four CHC directors antici-


Tuberculosis is a common and often deadly infectious disease caused by Mycobacterium tuberculosis. The cellular machines that drive the bacterium's metabolism is activated by a protein called LipBand therefore is a very promising drug target. The present study aims at finding out the best ligand that will bind efficiently with Lip B through docking analysis. The energy values were found to be promising for the drug prednisone which exhibitedan energy value of around -3.46 kcal/mol. and inhibition constant of around 2.89.Docking was done using Auto dock 3.0 and the docking analysis has shown that the drug prednisone has the maximum binding affinity with the molecule, thereby inhibiting the activity of the enzyme.


Based on the mutual relationship between tourism cooperation action and cooperation of tourism research papers,the evolution of the action and theoretical research phases are differentiated afresh,and the connection between the obvious features and evolution is consistent until 2006.The number of tourist cooperative action is stable,and tourism theory research has been growing after 2006.But both have not formed a virtuous cycle,theoretical study insufficient depth excavation succession.Subsequent research needs to improve the case analysis,creating the basic theory system innovation,strengthening the inheritance research.


This paper presents the design of a two key-frame visual inertial navigation system (2KF-VINS) using combined Lie group SE2(3) extended Kalman filter (EKF) design framework. The conventional 2KF-VINS filter is unobservable for translations along all three axis and rotation about the gravity direction. As a result, the filter suffers from estimation inconsistencies related to unobservable transformations of the estimation problem. The proposed combined Lie group SE2(3) framework remedies this issue by implicitly preserving the observability consistency property of the filter. Monte Carlo numerical simulations are used to validate the theoretical performance of the right -SE2(3) 2KF-VINS, along with experimental validation using EuRoC MAV dataset to evaluate the performance in real-world scenarios. Additionally, the proposed algorithm is compared with state of the art MSCKF VINS, right-invariant MSCKF VINS, left-SO(3) and right-SO(3) 2KF-VINS versions with identical and realistic tuning parameters in order to validate the performance related to accuracy, consistency, and computational speed of the method.


Land-use planning has not been worked as an efficient way for studying and mitigating impacts on urban ecosystems. Sustainable development, one of the altern...


The present invention provides a method for manufacturing a stator, which is designed to ensure the insulation between a conductor and an armature core, while preventing that production costs rise, and it is prevented that a space factor decreases. In an edge-removing step pressing several independent edges removal punches, corresponding to a slit S or two or more slits S, a corner portion of an opening edge in the axis direction of the slit in a core plate at one end in the axial direction of the armature core and slant it off.


Intestinal ganglioneuromatosis, part of the mucosal neuroma syndrome, is often associated with medullary thyroid carcinoma and pheochromocytoma. Barium enema studies demonstrate a distinctive triad of (a) an abnormal haustral pattern in the filled colon, (b) thickened mucosal folds on postevacuation films, and (c) colonic diverticula. These radiographic findings suggest the diagnosis of intestinal ganglioneuromatosis and raise the possibility of associated thyroid and adrenal tumors.


INTERNET AND MEDICAL PROFESSIONALS
The problem of on-line consultation
With the Internet, medical and mental health professionals are able to offer
on-line consultations. The French Medical Association has reacted by
banning this practice which it considers incompatible with the principles of
clinical medicine. It has nevertheless left open the possibility of using the
Net for certain acts apart from consultation. In the area of mental health, online consultation exists despite the fact that it has been condemned by most
professionals. It is practiced either by practitioners in favour of
experimentation in this field, or by commercial enterprises selling 'on-line
cures'. On-line consultation affords an opportunity for mental health
professionals to debate the issues of co-presence and remuneration.


Language teachers,especially secondary vocational language teachers must be in-depth study of teaching language arts,the use of science and art of teaching language to impart knowledge to students.This is by the characteristics of the language subjects taught in the main teaching object decision.Language teachers in classroom language should strive to do: full of emotion,self-assured,humorous aspects.