A series of novel 2-(substitutedphenyl)-5-methyl-3(phenylamino)-1,3-thiazolidin-4-ones ( 4a-g) were synthesized and structurally confirmed by elemental analysis, I R H NMR and MS spectral data. All the synthesized 1,3 thiazolidin-4-one analogues ( 4a-g) at various concentrations (10, 20, 50, 100 and 20 0 mcg/ml) have been evaluated for in vitro cytotoxicity against Dalton's lymphoma ascites (DLA) cancer cell line by trypan blue excl usion method, in comparison with standard drug doxorubicin hydroc hloride. Out of these seven compounds, three compou nds (2(2,4-dichlorophenyl)-5-methyl-3-(phenylamino)-1,3-t hiazolidin-4-one ( 4c), 2-(2,3-dichlorophenyl)-5-methyl-3(phenylamino)-1,3-thiazolidin-4-one ( 4b) and 2-(4-bromophenyl)-5-methyl-3-(phenylamino)-1, 3 thiazolidin-4-one (4d)) inhibited 70%, 68% and 61% DLA tumor cells at 1 00 mcg/ml concentration, whereas standard drug doxorubicin exhibit 100% DLA inhibition at a concen tration of 100 mcg/ml. From the above study, compou nd 4b, compound 4c and compound 4d which showed better results (> 60% inhibition) at lowest concentration were further selected for screening in vivo anticancer a ctivity against Dalton's lymphoma ascites (DLA) can er cell line at the dose of 50 mg/kg body weight/i.p. in compari son with 5-fluorouracil (20 mg/kg body weight/i.p.) by determining different parameters like body weight a nalysis, packed cell volume, viable tumor cell coun t, increase in life span (%), followed by hematological profiles [ red blood cell (RBC), white blood cell (WBC), hemog lobin (Hb) and platelet count] and serum biochemical parameter s [aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total cholesterol (TC) and triglycerides (TG)] of DLA bearing mice. In the in vivo anticancer evaluation, among t hree compounds screened, compound 4c emerged as more potent inhibitor of DLA with an increase in life span (ILS ) of 72.25%, whereas standard drug 5-fluorouracil e xhibit ILS of 92.13%. The in vivo anticancer experimental results indicated that, compound 4c (p < 0.05) and 5-fluorouracil (p < 0.01) showed significant decrease in body weight ga in, packed cell volume, viable tumor cell count and i creased the life span of DLA tumor bearing mice, followed b y hematological and serum biochemical profiles were significantly restored to normal levels in compound 4c (p < 0.05) and 5-Fluorouracil (p < 0.01) treated g roups as compared to DLA control mice .


Introduction: Periventricular leukomalacia (PVL), a type of hypoxic ischemic injury, is the most common cerebral pathology observed in neonates with congenital heart defects (CHD) [1]. While the exact reason for this type of white matter injury is unclear, hemodynamic and metabolic dysregulation is thought to play a role [2]. We utilized a previously described non-invasive magnetic resonance (MR) method that can measure global bi-hemispheric cerebral venous oxygen saturation (SvO2) and cerebral blood flow (CBF) simultaneously [3, 4]. The two measurements can be combined using Fick's law to yield global cerebral oxygen metabolism (CMRO2) in absolute physiological units. The goal of this work was to illustrate the feasibility of MR susceptometry based oximetry to quantify SvO2, CBF and CMRO2 in absolute physiological units at rest and in response to hypercapnia in neonates with CHD. The latter was evaluated to assess the dynamic range of the method and cross-validate MR based hemodynamic measurements with more clinically widespread optical methods. Additionally, pre-operative hemodynamic parameters were correlated with the incidence of PVL postoperatively.


The invention provides a pipeline safety pre-alarming and monitoring system for pre-alarming and monitoring pipeline safety in the third-party damage frequently occurred region. The invention relates to the measurement of mechanical vibration and impact, and the field of pipeline system technology. The invention is composed of the monitoring center and the monitoring unit, the monitoring unit includes multi-channel vibration sensors which are connected in sequence, signal adjusting module of central processing unit, logic control module, DSP digital signal processing center and GPRS communication module; the monitoring center is that the output of GPRS communication module connects to the input of the computer, the output of the computer connects with the display terminal, printer, alarming sound or communication module then with GSM separately; the vibration sensor is identified by the central processing unit in pattern identification, the identified signal feature and position information are outputted through the GPRS communication system to the monitoring center, after the secondary judgment by the monitoring center computer, the specific alarming information and position are given.


The modification of the surface chemistry of individual nanotubes inside vertically aligned carbon nanotube (VACNT) arrays is a key challenge in developing successful active materials for many electronic, photonic and catalytic applications. To this end, an efficient, clean, non-destructive and adjustable process for nitrogen functionalization and doping of the VACNTs in a controlled manner is highly required. In this study, the results of a systematic study using plasma discharge for this purpose by varying the N2/H2 gas volume ratio, discharge exposure time, and the radio-frequency (r.f.) power are presented. This process resulted in the generation of a few defects induced deliberately by the nitrogen radicals into the graphitic framework, mainly as in; amine, amide, pyridinic, pyrrolic, graphitic-type nitrogen. The parameters of plasma discharge were adjusted in a way that the densities and the relative ratios of nitrogen-containing functional groups can be selectively controlled. Evidence for the induced structural and chemical bonding changes, and the formation of different functional groups on the surface of the VACNTs are examined as a function of nitrogen content, using proper combination of analytical methods of high-resolution transmission electron microscopy (HRTEM), Raman, X-ray photoelectron (XPS) and Fourier transform infrared (FTIR) spectroscopy. At the relatively low level of r.f. power and discharge nitrogen flow rate in the feed, a preservation of the graphitic framework of the VACNTs has been demonstrated. The current study, therefore, sets the stage for selective control of the densities and the relative ratios of different nitrogen-containing acidic and basic surface functional groups on or within the nanotube framework under defined process parameters without causing a dramatic loss of graphitic structures.


Aim. To investigate the effect of Nocardia vaccinii ІMV B-7405 surface-active substances (surfactants) on adhesion of some bacteria and yeasts to fragments urogenital silicone catheters. Methods. The degree of adhesion of microorganisms was determined as the ratio of the cells amount on treated by surfactants catheters fragments to the amount of cells in the control (without surfactant treatment) samples and expressed in percent. Cell concentration was determined by the method of Koch meat-peptone agar and glucose-potato agar. Results. It was shown that the attachment bacteria (Escherichia coli IEM-1, Erwinia sp. TБ-4, Enterobacter cloaceae AС-22, Pseudomonas sp. MI-2, Proteus vulgaris ПA-12) and yeast Candida albicans Д-6 to the fragments of urogenital silicone catheters treated with N. vaccinii IMB B-7405 surfactants depended on the concentration and purification of surfactants, and the type of test cultures. Treatment catheters of N. vaccinii IMB B-7405 surfactant (0.05–0.08 mg/ml) was accompanied by decrease adhesion of bacteria and yeast by 21–95% and 57–94%, respectively. Conclusions. Thus, N. vaccinii ІMB B-7405 surfactant can be used for development of effective preparations decreasing the adhesion of microorganisms on the surface of medical application.


The swelling and mechanical behavior of untreated leather waste particles (buffing dust, BD) in natural rubber have been studied. Mechanical and swelling properties of the natural rubber (NR) composites containing the buffing dust have been discussed. The properties of the composites were found to increase with the increase in filler loading. Polymer composites based on leather wastes as fillers are reported to be useful for many applications such as in construction materials, automobile interior moldings, heat and sound insulating boards, shoe soles, flooring materials and moldings with good anti-static properties, air permeability, and good appearances.


Based on this study to determine the effect of training on employees work performance at Grand Inna Hotel Padang. This type of research_is causal associative. The sample used is total sampling, which is as many as 60 employees who are in the operational section, through a questionnaire with a Likert scale whose validity and reliability have been tested. The results obtained from this study are as follows: (1) training is in the very good category 68.33%, (2) employees work performance is in a very good category of 95%, (3) the results of testing a simple linear regression hypothesis obtained F for 8.649 with sig. 0.00 <0.05, then the training variable explains the variable employees performance of 13% and 87% influenced by other factors. Then the coefficient value of 0.248 is obtained with the value in sig. 0.00 <0.05. This means that each increase of 1 training unit will increase the 0.248 work achievement units of Grand Inna Hotel Padang employees.
Keywords: Training, Employee Performance


This paper presents a new QRS complex detection algorithm that can be applied in various on-line ECG processing systems. The algorithm is performed in two steps: first a wavelet transform filtering is applied to the signal, then QRS complex localization is performed using a maximum detection and peak classification algorithm. The algorithm has been tested in two phases. First QRS detection in ECG registrations from the MIT-BIH database was performed, which led to an average detection ratio of 99.50%. Then, the algorithm was implemented into a microcontroller-driven portable Holter device. This research is supported by the Hungarian Foundation for Scientific Research, Grant T29830 and FKFP0301/0999 Project.


In the backdrop of the 9/11 terror attacks in America, the state's increasing powers of surveillance, especially here in the United Kingdom, have been presented to us as essential in order to protect our society and the Western world from terrorism. This reflections aims to critically debate whether the state's use of surveillance is limited to just terrorism, or whether it threatens democracy for wider society, by impeding our ability and right to protest.


I use a co-evolutionary model to investigate the co-existence of species in ecological and evolutionary time in an environment that comprises a continuum of habitat heterogeneity. The model considers the ecology and evolution of communities organized by a trade-off in foraging costs over the environmental continuum. I assume that foragers use an optimal patch departure rule for depleting environments, where the rule itself depends on both the habitat and the forager's phenotype, which is a heritable evolutionary strategy. I consider the effects of three variables on co-evolutionarily stable co-existence: (1) travel cost, (2) maintenance and replacement cost, and (3) the range of habitat heterogeneity. When travel cost is positive, it, as well as the other two variables, affects species richness. Increasing either travel cost or maintenance cost results in a decrease in richness. Increasing habitat heterogeneity can increase species richness.


Cancellous bone is a porous type of bone found in the spine and at all articulating joints. It is a porous cellular solid, consisting of an irregular three-dimensional array of bony rods and plates, called trabeculae. Bone marrow fills the spaces of the pores. The study of cancellous bone is important, among other reasons, because the thinning of the trabeculae is a cause of osteoporosis. Hence determination of the porosity (pore space volume/total volume) of cancellous bone by acoustic interrogation would be useful in diagnosing osteoporosis. In view of the structure of cancellous bone Biot's model of a poroelastic medium as an elastic frame with a connected pore space filled with fluid may be applicable. Williams 4 , McKelvie and Palmer 3 , and Hosokawa and Otani have compared the predictions of the Biot model for cancellous bone with experimental measurements. In order to do this the parameters upon which the Biot model depends had to be determined. Some of the parameters were measured, but others were estimates taken from the literature or based


ABSTRACT Wasabi (Eutrema yunnaense) is a popular, commonly known as a specially health and a very precious flavoring food, which is served together with other foods, such as sushi and sashimi throughout the world. Isothiocyanate is the major flavor substance of wasabi which is extremely volatile, thus affecting the quality of wasabi products. The aim of this study was to obtain wasabi with the highest isothiocyanate content as well as other physicochemical and nutritional characteristics. Wasabi samples were dried by four different drying methods including, hot air-drying (HD), radio frequency-assisted hot air-drying (RFD), pulse-spouted microwave-assisted freeze-drying (PSMFD), and freeze-drying (FD). After drying, color, odor, taste, volume shrinkage, sensorial analysis, water content, and distribution as well as chlorophyll, ascorbic acid (vitamin C), and isothiocyanate content of the final dried products were measured. The drying time of each drying method was also measured. Highest contents of vitamin C, chlorophyll, and isothiocyanate of wasabi were obtained by FD followed by PSMFD. The volume shrinkage of wasabi dried by FD was the largest, followed by PSMFD, RFD, and HD, which is 0.992, 0.988, 0.894, and 0.882, respectively. The best color, highest sensorial scores, and small discrepancy (difference) of odor and taste substances from fresh samples of drying wasabi were obtained by freeze-drying which were close to PSMFD samples. As for drying time, RFD lasted 4.5 h compared to HD which lasted 9.5 h. PSMFD took 4.5 h less than FD (9 h).


Often encountered driving critical applications, synchronous machines (SM) require reliable condition monitoring systems. In this paper, the advantages of using the field winding current of a synchronous motor as an early indicator of machine faults are demonstrated. Analysis is carried out, both through simulation, via the use of finite element methods (FEM), and through experimentation, using a specially-designed synchronous machine which allows various fault conditions to be investigated such as eccentricities and short-circuits. It is established from the comparison of the spectra, between healthy and faulty field current data, that the field winding current is well suited for fault detection as well as discrimination among the common faults in SMs. Further, it is shown that field winding current is quite sensitive to any problem of the stator, permitting the detection of stator short-circuits at a very early stage. Thus, it is concluded that an improved condition monitoring and protection system for SMs may be achieved if the field current is effectively monitored.


The article offers the authors estimation of the sources from the book by the British historian Robert Kershaw War Without Garlands: Operation Barbarossa 1941-1942 (the Russian translation 1941 through Germans eyes. Birch-tree crosses for iron ones was published in Moscow in 2008). The book allows imagining the evolution of viewpoints of the combat operations in 1941 in the hardest war period for the USSR. The article gives an analysis of the evolution and assessments formulated by the book author R. Kershaw. The cited sources (letters, diaries of German soldiers and officers) prove convincingly that during the first months of the war die Wehrmacht faced serious problems that were the prologue of the coming defeat. The article offers opportunities of using the book materials in education process and in fighting falsifications of the history of World War II.


https://doi.org/10.4068/cmj.2021.57.3.226 C Chonnam Medical Journal, 2021 Chonnam Med J 2021;57:226-227 Corresponding Author: Young Joon Hong Division of Cardiology, Chonnam National University Medical School, 160 Baekseo-ro, Dong-gu, Gwangju 61469, Korea Tel: +82-62-220-5778, Fax: +82-62-223-3105, E-mail: email@example.com These authors contributed equally to this work. Article History: Received September 29, 2020 Revised January 16, 2021 Accepted January 17, 2021 FIG. 1. (A) Initial angiogram showed tortuous vasculature (arrow) in middle RCA, and intracoronary thrombus in distal RCA (arrowhead). (B) After balloon angioplasty and thrombus aspiration, (C, D) angiogram showed newly discovered thrombi in proximal, middle RCA (arrowheads), by thrombus migration. RCA: right coronary artery.


the mid-twentieth century. Living conditions in this public company town were generally much better than in private company towns where worker agency constantly met resistance from the power structures intent on producing surplus value. The freedoms and amenities residents enjoyed in Sunflower Village—including town newspapers, commercial buildings, schools, and even a town council—contributed to and reflected the workers' ability to create for themselves a landscape imbued with personal meaning.


A 64-year-old white female with a history of renal transplantation was admitted to our Hospital with increased blood pressure (185/100 mmHg) accompanied by peripheral edema and a creatinine level of 2.1 mg/dL. The patient had received a pediatric en bloc renal allograft due to end stage renal disease owing to diabetic nephropathy 3 years before current presentation. After transplantation, a stable baseline serum creatinine concentration of 1.2 mg/dL was achieved by maintenance immunosuppression therapy, while there were no episodes of acute rejection. Additionally, her baseline mean blood pressure was maintained at 120/65 mmHg with 2 antihypertensive medications. Thirty months postoperatively, her serum creatinine and blood pressure started to rise progressively, while she had also an extending peripheral edema, despite increasing doses of furosemide. Congestive heart failure was excluded by echocardiography, which showed left ventricular ejection fraction of 68%. MRA of the iliac arteries and renal allograft revealed a tight (90%) stenosis (fig. 1) at proximal part of the transplant renal artery. The patient was treated successfully with angioplasty and stenting; within 2 weeks, blood pressure was normalized, edema was resolved and serum creatinine returned to baseline of 1.2 mg/dL.


Four new homodinuclear isostructural luminescent EuIII and TbIII complexes containing N,N-heterocyclic bases (DPQ/DPPZ) and tolfenamic acid (TFA) presented as [Ln2(DPQ/DPPZ)2(TFA)6], where LnIII = EuIII [DPQ (1), and DPPZ (2)] and TbIII [DPQ (3) and DPPZ (4)], were studied in this work. The planar DPQ/DPPZ ligands used are well-known intercalators and photosensitizers. Tolfenamic acid (TFA) used as an anthranilic acid derivative-based NSAID, provides the hard carboxylate-O-donor for hard LnIII Lewis acids, and can form a bridge between two LnIII ions. The SC-XRD studies on the dinuclear complexes revealed their isostructural nature in the solid state. This is due to the similarity of both LnIII ions, exhibiting identical ligand disposition in 3D and electronic interactions with the ligands. All the complexes possess Ci symmetry, making the coordination environment around each LnIII identical. The two LnIII ions in the dimeric structures are bridged by –COO− groups of the four TFA molecules in a μ-η1:η1 coordination mode. Additionally, one TFA is coordinated to each LnIII in an η2-chelating mode together with one bidentate N,N-donor DPQ/DPPZ ligand. Therefore, each EuIII/TbIII ion ultimately possesses an eight-coordinated {Ln2N2O6} square antiprismatic geometry. The luminescent complexes showed the characteristic (5DJ → 7FJ) f–f transitions in solution with a quantum yield in the range of 8–20%, and thus were utilized for cellular fluorescence imaging studies. The affinity of the complexes with biological targets such as DNA and serum albumin was studied. The cellular uptake and bioimaging potential of the luminescent compounds in MCF-7 and HeLa cancer cells were probed using confocal fluorescence imaging studies. The sufficient internalization of the LnIII-probes in the cells observed from the intrinsic luminescence from EuIII/TbIII demonstrated their non-selective cytosolic and nuclear localization. The complexes were photo-cytotoxic at 365 nm mediated by the ROS generated from the photo-excitation of the DPQ/DPPZ sensitizers.


In the hyperdiverse Fungi, the process of speciation is virtually unknown, including for the >20,000 species of ectomycorrhizal mutualists. To understand this process we investigated patterns of genome-wide differentiation in the ectomycorrhizal porcini mushroom, Boletus edulis, a globally distributed species complex with broad ecological amplitude. By whole genome sequencing 160 individuals from across the Northern Hemisphere, we genotyped 792,923 SNPs to characterize patterns of genome-wide differentiation and to identify the adaptive processes shaping global population structure. We show that B. edulis exhibits contrasting patterns of genomic divergence between continents, with multiple lineages present across North America, while a single lineage dominates Europe. These geographical lineages are inferred to have diverged 1.62 to 2.66 MYA, during a period of climatic upheaval and the onset of glaciation in the Pliocene-Pleistocene boundary. High levels of genomic differentiation were observed among lineages despite evidence of substantial and ongoing introgression. Genome scans, demographic inference, and ecological niche models suggest that genomic differentiation is maintained by environmental adaptation, not physical isolation. Our study uncovers striking patterns of genome-wide differentiation on a global scale and emphasizes the importance of local adaptation and ecologically mediated divergence, rather than prezygotic barriers such as allopatry or genomic incompatibility, in fungal population differentiation.


The rate of teen pregnancy, although on the decline, still remains to be one of the highest among industrialized countries. As a result much emphasis is placed on finding effective pregnancy prevention interventions. A study of thirty-three adolescent females using a questionnaire was conducted to identify what types of interventions they had attended and what percentage had become pregnant. Findings indicated that those who attended more comprehensive interventions and abstinence based interventions were less likely to have been pregnant. The study also illustrated that timing of the attendance was important in that respondents who attended the intervention before becoming sexually active were less likely to become pregnant.


Hepatic arterial blood flow (HABF) and portal blood flow (PBF) were measured in 18 dogs while awake and during isoflurane and halothane anesthesia. Surgical preparation 1 week before the measurements consisted of a left thoracotomy, placement of a left atrial catheter, and insertion of another catheter into the distal aorta via the left femoral artery. Cardiac output and liver blood flow were determined using microspheres at three stages: stage 1—awake state; stage 2—after 45 min of 1 MAC of isoflurane (eight dogs) or halothane (10 dogs) anesthesia; and stage 3—after 45 min of 2 MAC of inhalation anesthesia. Half-life and fractional clearance for indocyanine green (ICG) were determined 1 day before the experiment (awake state), and at the end of stages 2 and 3. Mean arterial pressure (MAP) and cardiac index (CI), as well as PBF, decreased during isoflurane and halothane anesthesia. HABF increased significantly during isoflurane anesthesia, remained unchanged during 1 MAC of halothane anesthesia, and significantly decreased during 2 MAC of halothane anesthesia. Apparently, hepatic oxygen supply was maintained much better during isoflurane than during halothane anesthesia. PBF correlated with CI during halothane (r = 0.97) and, to a certain extent, with MAP during isoflurane (r = 0.66). HABF correlated with CI and MAP during halothane (r = 0.74 and 0.71, respectively) but did not correlate with systemic hemodynamic variables during isoflurane. ICG half-life significantly increased during 1 and 2 MAC of halothane anesthesia. The degree of increase did not correlate with the level of anesthesia or the decrease in total hepatic blood flow. Isoflurane anesthesia was not accompanied by significant changes in ICG half-life. The data suggest that halothane has a more deleterious effect on liver blood flow than does isoflurane and, in addition, interferes with liver cell ability to absorb and excrete ICG.


Using data from the Understanding Society survey, Kirby Swales explains that the relationship between income and financial well-being is more complex than often assumed, and so a broader view of living standards could give greater insights into how best to help people react to changes in the economy.


In the context of integrated joint operations, the demand for integrated equipment support is increasingly important. In this paper, we use genetic gray neural network method, combined with the analysis of factors affecting equipment support, take the quality of equipment reliability, equipment technical conditions, exercise training tasks frequency, equipment management level and historical data as indicators of network input and equipment demand as a network output, build genetic gray neural network model, avoiding the network falling into local optimum. By contrast, it shows that the model has higher accuracy.


The increasing capacities of renewable energy sources and the opportunities emerging from the smart grid technology lead to new challenges for energy forecasters. Energy output fluctuates stronger compared to conventional power produc- tion. More time series data is available through the usage of sensor technology. New supply forecasting approaches are developed to better address those characteristics, but meaningful benchmarks of such solutions are rare. Conduct- ing detailed evaluations is time-intensive and unattractive to customers as this is mostly handwork. We define and discuss requirements for ecient and reliable benchmarks of renewable energy supply forecasting tools. To cope with those requirements, we introduce the automated benchmark framework ECAST as our proposed solution. The system's capability is demonstrated on a real-world scenario compar- ing the performance of di↵erent prediction tools against a naive method.


Shrinking Data Systems As a result of efforts to develop a low cost portable flow cytometer for world health applications, Steven Graves and his research team led by Mark Naivar have demonstrated a new approach to developing small and inexpensive data systems. Taking advantage of microcontrollers, which are commonly used in automotive applications, toys, and portable electronics, a complete 4channel data system was developed using a single processor chip. In spite of the low power (<1 watt) and cost (<$20), the single chip can support many modern instruments. The most surprising finding was clearly resolving the dimmest beads from an 8-bead set analyzed on a FACSCalibur without the use of log amps. Notable features of interest include: FCS 3.0 format list mode data files, correlated waveform capture for off-line processing, an external trigger output, and a high resolution time parameter. In this issue: page 979 Moving past the objective in cytometry Traditionally, flow cytometers use a series of microscope objectives, lenses, and mirrors to collect and filter scattered and fluorescent light from cells. For accurate results these lenses must be kept in precise alignment over the lifetime of the instrument. Sitton and Srienc overcome these alignment issues by constructing a Teflon AF flow cell that functions as a liquid core waveguide. This flow cell directs light along its axis to a traditional fiber optic. Light in this fiber optic is then divided by a fiber optic splitter, filtered, and measured by PMTs. Compared to traditional cytometry the developed system is insensitive to reasonable mechanical forces and could form the basis of robust cytometers. This has the potential to make flow cytometers more transportable and expand their use into non-traditional settings.


We consider how a shared data network can effectively support connectivity-centric applications. Such applications include command dissemination and emergency alerts. These applications have low data rate requirements but depend critically on maximizing the fraction of messages sent that are delivered on time, which is called the connectivity of the network. Stresses that impair connectivity include low-quality wireless links, adversary action, network management errors, and high load. We argue that connectivity-centric applications require dedicated support at multiple layers. The network should provide two separate communications services, high-connectivity and high-capacity, with independent protocol stacks. The highconnectivity service trades resource consumption for improved connectivity at all layers and hence cannot be used for more than a small fraction of the overall traffic load. In addition to application data it carries control plane traffic critical to network operation and crisis recovery. The high-capacity service is a more traditional efficiency-optimized stack. We consider architectures for the high-connectivity service in both tactical wireless and core fiber networks. Within the overall architecture, we investigate in more detail path-diversity mechanisms for overcoming connectivity failures, and network segmentation to mitigate the effect of cyber attacks on the control plane.


This paper is a survey of open problems and results involving extremat size of collections of subsets of a finite set subject to various restrictions, typically on intersections of members .


[1] The correlation dimension D2 of precipitation (Canada and Africa), air temperature (Canada, New Zealand, and Southern Hemisphere), geo-potential height (Canada), and unregulated streamflow (Canada, USA, and Africa) were estimated using the Hill procedure of Mikosch and Wang [1995] and the bias correction of Wang and Gan [1998]. After bias correction, it seems that D2 is distinct between climate subsystems, such that for precipitation, it is between 8 and 9, for streamflow, it is between 7 and 9, for temperature, it is between 10 and 11, and for geo-potential heights, it is between 12 and 14. The results seem to suggest that climate might be viewed as a loosely coupled set of fairly high-dimensional subsystems and that different climate variables can yield different D2 values. Further, results also suggest that the D2 values of the climate subsystems studied, generally, have low geographic variability, as found between the precipitation data of Western Canada and Uganda, between the streamflow data of basins representing wide range climate and scales from Canada, USA, and Africa, and among the temperature data of Western Canada, New Zealand, and the southern hemisphere, and that the original D2 values analyzed from Canadian geo-potential heights are similar to that of Western Europe, eastern North America, and Germany. There is at most a weak relationship among basin physical characteristics, location, basin scale, and streamflow D2, while climatic influence is more obvious, as shown by drier basins having slightly higher D2 values than basins of wetter climate, basins from temperate climate having higher D2 values than those from cold or hot climates, and comparable D2 values between precipitation and streamflow data.


Today we all take care very much about environment because it degrades day by day for several reasons; one of them is the accumulation of heavy metals which are one of the intrinsic components of this environment. The excessive accumulation of heavy metals affects all sides' viz. air, soil, water of our beautiful environment through their adverse impacts. There are too many sources open till now for helping them to enter into the environment. This paper shows how they enter together and affects food chain, plant growth, seed germination, photosynthesis and so many. Excess accumulation of both types of heavy metals viz. essential (Zn, Cu, Fe etc) and non-essential (Pb, Hg, As etc) are responsible for disturbance of both aquatic as well as non-aquatic environment parallelly. Human beings also face slow but steady affect either direct or indirect way. So, we try to reflect how toxic level of heavy metals contamination poses a serious threat to our living environment.


CIVIL RIGHTS DEFENCE COMMITTEE. THE ANDERSON (PRIVY COUNCH) APPEALS. THE Civil Rights Defence Committee has forwarded the appended list of further subscriptions to the Anderson (Privy Council) Appeal Fund. The Committee desires to state that it is much encouraged and strengthened by the action of those Branches of the British Medical Association which have voted subscriptions from the Branch funds in aid of the defence entrusted to it of the professional and public rights involved in Mr. Anderson's appeals, and of those Branches of the British Medical Association and divisions of the London and Counties Medical Protection Society, and of those gentlemen that have kindly taken charge of lists and collected subscriptions. Time is, however, passing, and a considerable further sum, about £850, is, as has been already stated, necessary for the conduct of these appeals to the Privy Council to a satisfactory issue, and of this at least £100, but to move to the best advantage £150, is required, before the special leave to appeal can be applied for. The papers and proceedings up to this stage, including many cffice copies from, and searches in, Trinidad, have been prepared and taken and paid for out of the funds raised, and there is at present, when all subscriptions promised are received, a balance of£45 available. If a uniform subscription of five shillings could be obtained from one tenth part of the medical profession of the Empire, or of half-a-crown from one fifth part or of one shilling each from one half of the profession, the defence of rights declared by all public bodies, journals, and individual members of the profession that have expressed themselves to .be essential to the practice and existence of the profession, need no longer be left open to question and subject to encroachment. The Committee beg to invite co-operation in organising a general uniform subscription of five shillings or half-a-crown. and to appeal to public bodies the Committee represents and to the divisions and branches of those bodies, to aid in this work and to subscribe such sums as they can devote to it, and as will express their sense of the importance to the profession of the rights involved. Copies of the interim report will be sent to Branches about to hold meetings, and, as far as possible, to the members of those Branches, but the Committee will be very much obliged if honorary secretaries of, and Branchesand divisions of, the bodies represented on the Committee and members of the profession willing to assist in the collection of subscriptions will apply for such copies as they may require. In continuing and renewing its appeal, the Committee conveys to each member of the'bodies represented on it the appeal of each of those bodies to its own branches or divisions and to its own members: and in bringing this application urgently before public bodies and individuals that have not as yet had the appeal brought to their notice, the Committee earnestly invites consideration of the several votes adopted and opinions expressed by public bodies and men of high standing in the profession to the effect that deprived of the rights which Mr. Anderson is defending, the practice of the profession as a means of livelihood would be (as it was rendered to him) impossible, and the position of medical men one of intolerable degradation. Lord Stamford and the Committee feel therefore the greatest confidence in appealing to every feeling of public spirit and of personal generosity for the aid necessary to enable Mr. Anderson to bring to a successful issue his difficult and meritorious defence of most valued professional and public rights.


In this paper we propose a new approach of tomographic image reconstruction using sinogram interpolation for a sparse projection data. In this term, sinogram interpolation is a process of converting a sampled projection to a higher sampling rate projection. By using interpolation, we construct a new projections within the range of set of projection, then we apply a filtered backprojection reconstruction to get the tomographic image. This proposed approach reconstruction is applied to simulated half full angle projection data of the Shepp-Logan phantom with sparse angular sampling. The result are better than those given by filtered backprojection reconstruction without sinogram interpolation. Keyword tomography, projection, sinogram, interpolation, backprojection


By analyzing the uncertain region topological relation,aiming at "egg-folk" model shortcoming that its logical relation among 46 topological relations are not clear,this paper obtains 93 topological relations through dynamic change of closest topological distance graph,by cutting out 41 topological relations contain tangency relation and 6 repetitive topological relations,46 topological relations are obtained too,which are consistent with Cohn theory,thus "egg-folk" model is popularized.


In order to improve flexibility,expansibility,reusability and dynamic adaptability of CAPP system,the system architecture and the implementation method of an intelligent CAPP system under concurrent engineering environment which have such qualities as intellectualization,integration,reconfigurability,expansibility,and dynamic adaptability and distributed cooperative function,based on Multi-Agent system is put forward in this paper.


Enhancing the training of college students' listening and speaking ability is to meet the social needs in the new period,and it is also the main component in teaching reform.It is an important subject for us to think over.We should constantly improve the training methods to develop the students' intelligence and potentials and to produce active effect.


A novel detecting circuit of EEG signals used for BCI is designed,which adopts the resistance capacitance coupled circuit,common mode signal sample driver,active shield driver and floating power supply.Compared with similar circuit,the proposed circuit has advantages of simpler structures,strong anti-interference ability and good reliability.Through simulation and actual circuit debugging,the results indicate that this circuit can filtrate the noise and interference effectively,and detect the EEG signals well for BCI.


Assisted gait monitoring could benefit from the measurement of feet position and orientation. These measurements could also be used to implement intention-based control laws for smart walkers. Several works have been dedicated to the detection of lower limbs. The proposed methods are usually fast, but only detect the position of the legs. Others may even be more complete, but are not adapted to reactive applications. Also, they often use markers attached on the feet, which is unsuitable in daily routine. In this paper, a fast feet position and orientation detection algorithm is proposed. It is based on a camera depth sensor and does not require the use of any marker. The obtained results are compared with a ground truth provided by a motion traking system to experimentally assess the performances of the proposed algorithm.


ABSTRACT Purpose To describe and assess the cataract experience of ophthalmology residents throughout the United States (U.S.). Methods Cataract procedures logged by graduating ophthalmology residents nationwide and published by the Accreditation Council for Graduate Medical Education (ACGME) from 2009 to 2020 were analyzed using linear regression on log-transformed response variables with robust variance. Results As primary surgeon, average numbers logged for phacoemulsification increased yearly by an average of 4.1% prior to 2019 and then decreased by 22.1% in 2019 for an overall average yearly increase of 2.9% (95% CI: 0.5, 5.4%, p = .03), non-phacoemulsification extracapsular extraction decreased yearly by an average of 4.6% (95% CI: −7.7, −1.5%, p = .01), other cataract/intraocular lens surgeries decreased yearly by an average of 8.4% (95% CI: −10.1, −6.6%, p < .001), anterior vitrectomies decreased yearly by an average of 12.5% (95% CI: −14.9, −10.1%, p < .001), and laser capsulotomies increased yearly by an average of 6.0% prior to 2019 and then decreased by 3.0% for an overall average yearly increase of 5.3% (95% CI: 4.5, 6.2%, p < .001). As assistant, average numbers logged in all ACGME minimum categories showed decreasing trends. Conclusions Over the last decade, the average numbers of phacoemulsification and laser capsulotomies logged by residents as primary surgeon increased while other ACGME cataract minimum procedures decreased. Surgical volume in 2019–20 was lower due to the coronavirus disease-19 pandemic but higher than from 2009 to 2013.


This study was conducted to explore the effectiveness of speech to text as a form of biofeedback intervention for speech sound production in children with articulation disorders.

 A multiple-baseline across-participants design was used for this study. Speech-to-text biofeedback was implemented with three children aged 7–9 years who demonstrated consonantal articulation errors. Data regarding accuracy of target phoneme production were repeatedly collected across baseline, treatment, and probe phases.

 Based on the preliminary data collected and analyzed during this study, results suggest that speech to text is an effective approach for addressing speech sound production. All three participants demonstrated improvement in the production of their target phonemes. In addition, all of the participants maintained their skills posttreatment.

 The results of this study provide initial support for the use of speech to text for children who demonstrate articulation disorders. Implications for future research and practice based on the results are discussed.


The trust system originated from England has its own unique historical and cultural origin and distinctive legal foundation, therefore, the interpretation of the trust property rights could not be made in the academic angle but in historical way. Only on the basis of grasping the specific historical condition and social environment and mastering the duality legal structure of Common Law and Equity and the Doctrine of Estates in the Common Law System, could we understand the legal characteristics of the relevant trust property rights in the right way.


For the coal face for eight coal mine guns by the special needs,and devised a monorail crane.Monorail this light,the structure of the crane,a process and its use are introduced,it is mainly used for coal on the progress of the lane in the course of transportation and support economic,technology,safety and easy to promote practical advantages.


This paper deals with Extreme Learning Machine (ELM) based sensorless speed estimation and speed control of Permanent Magnet Synchronous Machines (PMSMs). ELM, first proposed by G.B. Huang as a new class of learning algorithm for Single-Hidden Layer Feedforward Neural Networks (SLFNs), is extremely fast and accurate, and has better generalisation performance than the traditional gradient-based training methods. To implement Field-Oriented Control (FOC) in PMSMs, the stator magnetic field is always kept 90 degrees ahead of the rotor. This requires rotor position information all the time. This information is accurately obtained with an ELM-based observer without the position sensor for PMSMs, and hence, the cost of the system is reduced, while the problems associated with the sensors are minimised.


We present a silicon microring modulator with a 1 V drive voltage to achieve a 6.8 dB modulation depth at 10 Gbps. This drive voltage enables the modulator to be directly driven by CMOS electronics.


The article analyses psychological issues of reviving and developing entrepreneurship in Russia during the transitional period of social development. We provide the outcomes of a series of studies of psychological problems of ownership change and the rise of the new Russian entrepreneurship. The transition to a market economy in the early 1990s led to the emergence of new forms of property relations, which the majority of Russians were not ready for. A particularly glaring psychological problem was the specific administrative experience which had developed during the Soviet years and made post-Soviet executives unprepared for survival in a free market. The revival of entrepreneurship as an institute psychologically perplexed a significant part of executives. This was due to the uncertainty of the vectors of socio-economic development, which caused a mismatch of social expectations and shaped controversial psychological relationships. The attitude of post-Soviet executives to their future economic activity are considered here within the context of the theory of psychological attitudes (developed by V. P. Poznyakov) as personal attitudes. In this vein, these attitudes represent the views of post-Soviet executives on various conditions and aspects of the socio-economic transformation, attitudes to themselves as its subjects and to representatives of other social groups they are linked with by economic and other ties. Thus, psychological relations between subjects of economic activity, on the one hand, reflect the objective economic conditions and are shaped by changes in these conditions. On the other hand, by regulating economic behavior and, above all, the business activity of the subject, they themselves become factors of change of these conditions. This makes them predictors of real economic relations and a source of social development. Our historical and psychological analysis of the revival of entrepreneurship in Russia helped us conclude that the rise of the new Russian business was accompanied by a number of emotionally charged psychological difficulties, which effectively marked the emergence of a new social group in contemporary Russian society. They are the bearers of new life values which have persisted and are being spread and transmitted at present.


ABSTRACT This article focuses on two users of early portable computers – the 'road warrior' and 'digital nomad' of the 1980s and 90s – to illustrate how portability has served an imperialist function in engineering a world fit for buffering privileged subjects against conditions of existential precariousness. The label 'road warriors' emerged in the early history of portable computers as a reaction against the hostile environs of airports and aeroplanes, spaces that were deemed unaccommodating to the use of laptops. These complaints made clear the importance of portable milieus, spaces that had to come into existence to accommodate the transversal of portable computers. The article examines how these emergent portable milieus functioned also as pedagogical habitats, worldly enclosures that guided white, middle/upper-classed, male executives on the means to adapt to a precarious economic existence. Drawing from computer magazines, news articles, and the manifesto Digital Nomad, the article illustrates how these habitats romanticized the value of remote workers, legitimated their transformation of environments, and laid a foundation for the world to be engineered as a buffer for privileged populations. The trend of digital nomadism today which seeks to create opportunities for the austere good life amidst endemic economic problems in the West, speaks to the currency of this imaginary and the longstanding politics of remote work, ushered in by portable computers.


Lawrence Buell. Literary Transcendentalism: Style and Vision in the American Renaissance. Ithaca and London: Cornell University Press, 1973. 336 pp. James Mcintosh. Thoreau As Romantic Naturalist: His Shifting Stance toward Nature. Ithaca and London: Cor- nell University Press, 1974. 310 pp. New England transcendentalism is largely a psychological phenomenon em- bodying epistemological, philosophical, religious, social, and aesthetic consid- erations. Epistemologically, it rebels against complete reliance on sense experi- ence, and defends intuition or imagination as a vital source of apprehension of truth or reality. Philosophically, it stands for creative idealism as fundamental to the discovery of the meaning of the whole of creation. Religiously, it typifies the concept of an organic universe in which Nature is ripe with an immanent God, in which man and woman partake of the divinity of their Creator, and in which miracles seem possible. Socially, it insists on individualism, on individual moral insig...


Critical care services are atypical in the wide heterogeneity of their patients. This is in part a reflection of the way in which these services have evolved. The progress of intensive care in the UK has been described as 'haphazard', consisting of 'largely unplanned and unevaluated' developments that occurred in reaction to changes in surgical and medical practice. There has been debate about the configuration of critical care services, fuelled by a perception that there are not enough beds in some parts of the country and that existing beds are not in the right places. During the late 1990s, the NHS Executive established a National Expert Group to review adult critical care services in the UK and to produce a national Framework for future organisation and care delivery. As a result, in May 2000 a critical care modernisation plan was announced.


In this paper,we describe and design a portable heart sound recorder.The program in this paper filters the environmental noise out by the active analog filter and extracts the real-time data of heart sound.By the use of the AD module in the DSPIC chip,we digitize the heart sound and process it.The firmware records the heart sound in FAT32 file system format into a SD card.The software in PC written by LabVIEW traces the heart sound stored in the SD card in the time domain.According to the time domain graph of heart sound,doctor can do further analysis and judgment.This design solution has good market value as it can improve the diagnostic effect with its ability of capturing random abnormal heart sound.


This article offers an historical perspective and overview for treatment of thoracic aortic aneurysms. The classic technique, design, and delivery system are detailed. It outlines patient selection, the endovascular procedure, and interaction with the vascular surgeon. The authors describe their results as well as complications, and give an overview of this new and highly specialized treatment.


The RAM engineering and economic concepts applicable to the power industry are presented. These concepts are used to explore the economic impact of availability changes for a typical 500 MW base loaded coal fired power plant. A financial model of the plant is derived showing major allocations of costs and revenues, both under normal operation and with the plant down. The financial model is applied to an example considering different condensate pumping system arrangements and an example considering spare turbine rotors. Both examples explore the replacement power cost required to meet loads and evaluate capital-expense trade-offs to achieve increments of availability. Economic factors are assumed for time frames beginning in the mid-80's and all economic evaluations are performed using life-cycle costing and present worth techniques.


A speed regulator and control system for controlling a motor from a polyphase AC source includes a data processor and a regulator and rectifier control interfacing the data processor with a controllable rectifier driving the motor is disclosed. The regulator and rectifier control, under control of the data processor, selectively transfers system parameters to the data processor, receives a calculated value proportional to firing angle from the data processor and supplies firing pulses to the rectifier to selectively connect each phase of the AC source to the motor as calculated by the data processor.


A groph is a topological space consisting of finitely many points, called vertices, and of simple arcs, called edges, each of which joins a pair of vertices. In particular, an edge is called a selfloop if both two ends coincide, and a pair of edges are called multiple eciges if they join the same pair of vertices. Our graph is usually assumed to be simple, that is, to have neither self-loops nor multiple edges. Our main object in this paper is an embedding of a graph G into or on a closed surface F2. To specify how G is embedded on F2, it is effective to regard an embedding as an injective continuous map f:G->F2. We however deal with G and f(G) as the same one intuitively. Thus, G=f(G) is a subset or a subspace of F2. An embedding of G on F2 is called a 2-cell embedding if each component of F2-G, called a face of G, is homeomorphic to the open 2-cell {(x, y)ER2:x2+y2<1} and G is said to be 2-cell embedded on F2 in this case. Let G be a graph 2-cell embedded on F2 and choose two faces A and B of G so that they share an edge e. Then A UBUe forms an open 2-cell region on F2 with circular boundary and e is placed in this region as one of its diagonals. Roughly speaking, the diagonal transtbrmation appearing in the title is to replace this diagonal e with another diagonal. In particular, we focus the diagonal transformations in triangulations and in quadrangulations and discuss the equivalence over such classes of graphs under diagonal transformations. This paper presents a survey and several observations for further research on this topic, with Negami's and Nakamoto's recent results in ' [9] and [6].


The present study sought to examine the perceptions of giftedness and identification procedures held by experienced teachers of gifted minority students. Twenty-seven 4th-grade teachers of gifted students in an urban school system with a high representation of minority and economically disadvantaged students were surveyed. Results indicated that experienced teachers still held a narrow conception of giftedness and were not aware of how culture and environmental factors may influence the expression of giftedness in minority and economically disadvantaged students. Findings also indicated that these teachers expressed concerns for approximately one third of their students qualifying for the gifted program. These concerns were based primarily on students having a skill deficit in one area, poor work habits, or behavioral or family problems. Teachers were less likely to notice gifted characteristics in these students compared to other identified students, even though both groups were identified in the same way. Implications for teaching gifted minority and economically disadvantaged students are discussed.


Insular lesions are known to be very difficult to locate. They are often misdiagnosed as frontal lesions, temporal lesions, frontal-temporal lesions, and thalamic lesions. 1 Moreover, because of the complex anatomy surrounding the insular lobe, severe postoperative complications are considered. Removal of the temporal lobe plus a subtotal tumor resection is carried out even biopsy or non-surgical treatment is advocated. Consequently, few reports have been published on the clinical features of insular lesions and their operative treatment. 2 In 1992, Yasargil and colleagues 3 reported the surgical results of 177 cases of insular lesions in the limbic system ( including 57 cases of insular lesions). According to their opinion, lesions in the insular lobe can be resected safely via the transsylvian approach. Vigorous research into the normal anatomy and vasculature of the insula has greatly enriched our knowledge of surgical anatomy. 1 , 2 , 4 We report here 42 patients who were treated surgically at our hospital and discuss the clinical features, operative techniques, anatomic basis of postoperative complications, and how to avoid these complications.


What makes the city of Jala, Nayarit different and attractive is its cultural life
from the mid-sixteenth century, which makes reference to a set of features that are
remembered and recreated into our present times. This interest not only has to do
with nostalgia, but also with the quality and way of life that modernity has destroyed
and continues to destroy, and feeds on realities that have left their mark on the urban
environment. For many of its inhabitants preserving and recalling is a cultural position
that seeks to defend a way of life in the city. In the act of reminiscing, its residents
show interest in defining what is worthy to remain. Its value does not depend
on its minimal or grand antiquity and beauty, but rather in the measure that it informs
us of its history and conforms to the present maintaining its form of life current.


The proliferation of vascular smooth muscle cells plays an important role in the initiation and aggravation in cardiovascular diseases such as hypertension, arteriosclerosis, restenosis. This article reviewed the progress in the studies on extracellular influencing factors, intracellular signal transduction, cell cycle of vascular smooth muscle cells and the relative drug research and development.


This study aimed to obtain empirical evidence on the mediation effects of tax awareness mediation on the relationship between tax evasion and tax compliance. This research used an online survey through Google Forms. This study's population is taxpayers in the East Java region. Respondents were selected using purposive sampling techniques. In determining whether there is an influence of mediation, the Sobel test was carried out using Jose's Medgraph Online Software. The results showed that the level of tax awareness partially mediates the relationship between tax evasion and motor vehicle taxpayer compliance.


Although evidence of the protective immunity conferred by B‐1b cells (CD19+B220+IgMhiMac1+CD5−) has been established, the mechanisms governing the maintenance and activation of B‐1b cells following pathogen encounter remain unclear. B cell–activating factor (BAFF) and a proliferation‐inducing ligand (APRIL) mediate their function in mature B cells through the BAFF receptor (BAFFR) and transmembrane activator and CAML interactor (TACI). BAFFR‐deficient mice have lower numbers of B‐1b cells, and this reduction is directly proportional to BAFFR levels. The generation of B‐1b cells is also dependent on the strength of B cell receptor (BCR) signaling. Mice with impaired BCR signaling, such as X‐linked immunodeficient (xid) mice, have B‐1b cell deficiency, indicating that both BCR‐ and BAFFR‐mediated signaling are critical for B‐1b cell homeostasis. Borrelia hermsii induces expansion and persistence of B‐1b cells in xid mice, and these B‐1b cells provide a heightened protective response. Toll‐like receptor (TLR)–mediated stimulation of xid B cells results in a significant increase in TACI expression and restoration of TACI‐mediated functions. The activation of TLR signaling by B. hermsii and BCR/TLR costimulation–mediated upregulation of BAFFR and TACI on B‐1b cells suggests that B‐1b cell maintenance and function following bacterial exposure may depend on BAFFR‐ and TACI‐mediated signaling. In fact, the loss of both BAFFR and TACI results in a greater impairment in anti‐B. hermsii responses compared to deficiency of BAFFR or TACI alone.


Satellite observations of sea ice freeboard are integral to the estimation of sea ice thickness. It is commonly assumed that radar pulses from satellite‐mounted Ku‐band altimeters penetrate through the snow and reflect from the snow‐ice interface. We would therefore expect a negative correlation between snow accumulation and radar freeboard measurements, as increased snow loading weighs the ice floe down. In this study we produce daily resolution radar freeboard products from the CryoSat‐2 and Sentinel‐3 altimeters via a recently developed optimal interpolation scheme. We find statistically significant (p < 0.05) positive correlations between radar freeboard anomalies and modeled snow accumulation. This suggests that, in the period after snowfall, radar pulses are not scattering from the snow‐ice interface as commonly assumed. Our results offer satellite‐based evidence of winter Ku‐band radar scattering above the snow‐ice interface, violating a key assumption in sea ice thickness retrievals.


This research aims to explore free search engine optimisation (SEO) and social media plug-ins and compare their performance in increasing incoming web traffics. We create three publisher websites: the normal website without any SEO installed on it, the customised website with basic SEO configuration and social media plug-in, and the customised website with advanced SEO configuration and social media plug-in. We run and trace the website log for four and seven months. Our findings show that SEO plug-ins is capable to increase traffic to publisher website. Social media plug-in provides additional benefit to bring traffic, however, the traffic is less significant compared to the one from search engine. These findings have implications to the following: 1) the organisations need to pay attention on the way they organise information in their website; 2) the introduction of search ability aspect for measuring service quality for web application.


In recent years computer aided engineering techniques has developed to great extent, the choosing right materials and processes are great challenge for the engineers. This paper discusses about material and process selection based on computer aided technique. The output from all CAE tools is based on the accuracy of the provided input, therefore the requirement for using this tool is to understand the behaviour of the product and to specify the appropriate input. The CAE Techniques provides better understanding of the processes and material selection and helps to modify the products as it is essential to compitate in today's global market. The one such software is CES, (Cambridge Engineering Selector) which is used to modify the material selection and manufacturing processes used for the pedestal of the gearbox without affecting the functional requirements. This paper illustrates various consideration made for modification and the material and process of pedestal. The performance of the existing material and modified material is evaluated using finite element analysis and comparison of result is shown.


Entblofien here recalls the psychiatric technique of stripping defense mechanisms especially in view of its linkage with guilt, signaled by the word unschuldig. With its connotation of being open to attack or to accusations, it also alludes to the idea of the text as aggressor and witness. If, as Paul Ricoeur says, the breakthrough of language toward something other than itself is "saying" and "saying is showing," and if the force that language utilizes is a force "which discovers, which manifests, which brings to light,"2 then the uncovering by the act of language is in a sense the analogue of the uncovering by the act of looking or seeing. In fact, the importance of seeing in the work of Lenz has already been pointed out,3 and the centrality of the motifs of observation


The paper is devoted to study the Bianchi type VI0 space-time filled with Bulk viscous in the framework of f(R) gravity. The model initially accelerates for a certain period of time and decelerates thereafter .The physical and kinematical features of the models are studied and discussed. The function f(R) of the Ricci scalar is also evaluated for the model. PACS codes: 04.20.-q; 04.20.Jb; 04.20.Dv; 04.20.Ex


Background: Acute intestinal obstruction is one of the most common surgical emergencies worldwide. Mortality and morbidity increase markedly with late presentation. So, it demands an increased awareness regarding the danger of delaying the treatment. This study aims to explore the causes of delay in operative treatment for Acute Intestinal Obstruction. We carried out the study in the Department of Surgery, Combined Military Hospital, Chattogram Cantonment, Bangladesh. A total of 50 patients were prospectively studied, evaluated, and managed. Patients of acute intestinal obstruction attend in Department of Surgery, Combined Military Hospital Chattogram (CMH Chattogram). The patients were divided into six age groups. A maximum of 18(36%) number was found in 51-60 years, and the mean(±SD) age of the study patients was 39.9±16 years with a range from 1-65 years. In the sex distribution of the study patients, it was observed that 41 (82%) were male and 09 (18%) were female. Forty patients (80%) had no history of previous abdominal operations. Ten patients (20%) develop a single complication, while 13(26%) develop multiple complications. Acute intestinal obstruction is one of the most typical surgical emergencies worldwide. A large proportion of patients with acute intestinal obstruction do not receive appropriate treatment due to pre-admission delay resulting in poor outcomes.


Note: Proc. 12th European Conference on Contr. Fusion and Plasma Physics, Budapest, September 1985, Europhysics Conference Abstracts, Supplement to the proceedings Part I, 48 - 51 (1985) Reference CRPP-CONF-1985-026 Record created on 2008-05-13, modified on 2017-05-12


The renewable energy source has become the important composition of the energy strategy in the developed countries and it is also the important method for the lower carbon economics development in these counties. All these come from the specific characteristics of the renewable energy, such as the advantages of both environment and application. However, it is still the starting stage for the application of the renewable energy in China. Therefore, the higher cost makes it impossible to compete with the traditional energy and the pricing strategy becomes the bottleneck. Based on the marginal opportunity cost theory of sustainable developing natural sources, this paper concentrates on the value composition of the renewable energy and demonstrates them by the way of the dynamic model, which reflects the relations among all the energies. The calculating model is forwarded and it improves the policies for the renewable energy industry, aiming at the development of the competition advantage for our country.


The article describes some aspects of understanding legal values and legal obligations in modern legal science.To achieve the goal of the study, the author envisaged the performing such tasks as: clarifying the understanding of legal valuesand legal obligations used by legal science; proving the possibility of recognizing a legal obligation as a legal value; formulation of theconcept of legal obligation as a legal value.The author traces the interrelation between legal values and the legal order, emphasizing that without legal values, the rule of lawis ineffective, in turn, – legal values outside the legal order have no practical content.Based on this, the author proposes his own definition of the concept of legal values as ideal legal entities and principles that determinea person's perception of the importance of law, assessment of phenomena occurring in society through law, form a certain modelof legal person's behavior and are designed to ensure legal order and discipline in society.Given this understanding of legal values, as well as the position of modern legal science on the essence of legal obligation, theauthor defines the concept of legal obligation as a legal value: this is a legal prescription which is formulated by the state as necessaryto ensure law and order model of individual behavior, established in order to maintain the proper functioning of society as a collectivewhole and to ensure the interests of all its members, and fulfilled on the basis of the perception of certain behavior as fair and sociallyappropriate. The author's approach to the justification of a legal obligation as a legal value is proposed due to the following factors: theperson's perception of the relevant behavior as necessary, fair, socially acceptable, which expresses a socially significant benchmark;the formulation by the state through the legal norm the socially significant behavior; realization through such behavior the human socialnature as a part of the collective whole; the implementation of the principle of interdependence and complementarity of the rights andobligations of the individual.


The antagonistic fungi Gliocladium roseum 11, Penicillium frequentans, Trichoderma atroviride 312, T harzianum 144 and T. longibrachiatum 9 were grown with cell wall constituents of the foot rot pathogens Fusarium avenaceum, F. culmorum, F. graminearum and F nivale as sole sources of carbon. Production ofthe hydrolytic, cell wall-degrading enzymes N-acetyl-β-D-glucosaminidase, chitin 1,4-β-chitobiosidase, glucan 1,3-β-glucosidase and protease was assayed in culture filtrates. All antagonists produced the chitin and glucan-degrading enzymes when grown in presence of all the pathogens. The highest level of N-acetyl-β-D-glucosaminidase (19.52 ± 0.057 U and 19.10 ± 0.258 U) were recorded for G. roseum 11 in combination with cell walls of F. graminearum and F. nivale, while the highest level of chitin 1,4-β-chitobiosidase activity (9.38 ± 1.714 U) was determined for G. roseum 1 1 in combination with F culmorum. Compared to G. roseum 11, Trichoderma spp. and P. frequentans produced relatively low levels of these enzymatic activities. Regarding the glucan 1,3-β-glucosidase activity, T. atroviride 312 generally showed the highest level of activity, mostly pronounced with cell walls of F. graminearum (51.98 ± 2.37 U). P. frequentans showed a consistent production of protease, while only a few of the other combinations of antagonists and pathogens produced any detectable level of this enzymatic activity. It is concluded that the above reported enzymatic activities may contribute to explain the parasitism of the antagonists against Fusarium species involved in foot rot disease of wheat, although other modes of action of the antagonists such as antibiosis, competition or induced resistance cannot be excluded.


The debt ratio level of enterprise has noting to do with the total economic benefit. The analysis is based on the relations between enterprise's economic benefit and legal person's benefit, between proprietor's benefit and total economic benefit. Through the analysis to show the wrong viewpoint that reduce the debt ratio can raise economic benefit, and the blind chases of debt for equity swap, placing share with high price , issued more new share. The paper is also explore the influences of proprietor's benefit and how to assess debt ratio correctly.


Retentive force may be increased in deeper undercuts. Three clasps were examined for this hypothesis in order to analyze the retentive force change properties for each clasp design with increasing undercut depth only. A total of 36 cobaltchromium clasps, using half-round pattern and standard casting technique were fabricated. Three groups of clasps; RestPlate-Akers system, half-half, and Akers were engaged in 3 increasing undercut depths (0.25, 0.35, and 0.5 mm) on natural premolars. The test model was stone duplicate of plastic replica. Clasp retentive force was measured using universal testing machine. The results showed that the retentive forces for the tested undercuts (0.25, 0.35 and 0.5mm) were 8.59±1.89, 14.74±2.70 and 15.21±1.17 N for Akers; 3.06±0.88, 4.26±0.29, and 5.9±0.53 for half-half; and 0.9±0.15, 2.06±0.60, 2.3±0.50 N for Rest-Plat-Akers system respectively. Besides, the retentive force for each clasp design increased in a different way with each incremental augmentation of undercut depth. As a conclusion, changing the undercut depth altered the retentive force of the used clasp. Therefore, a clasp chosen for a definite undercut depth also can be used for deeper undercut on the same abutment when higher retentive force is required with respect to the other indication criteria.


The optimal design process based on CAE of parts design was introduced,the optimal design models have been built.Based on the Ansys system,the optimal structure design of U_shaped bellows was satisfactorily achieved.


Important thought of Jiang Zemin"three represents"is the theoretical summary of the international communism movement experience and construction of the Communist Party of China,is that Marxism party founds theoretical new development,is new period the great indicator of the construction of party.In new period,the ideological construction of party must be guidance with the thought of""three represents",keeping pace with the times,developing Marxism creatively,build the thought of""three repre-sents"as the thought of party important content,and implement in the specific action of the masses of cadre of party members.


Tornadogenesis occurs in a variety of storm types, or convective modes, each having a unique climatology and challenges in their detection and warning. Some warnings result in false alarms, meaning that no tornado occurred within the warning polygon. We used a mixed-methods approach to assess how convective mode––discrete supercell, cell in cluster, cell in line, or quasi-linear convective system (QLCS)––affects the tornado climatology and National Weather Service (NWS) procedures within three County Warning Areas (CWAs): Memphis (MEG), Nashville (OHX), and Morristown (MRX), Tennessee. We used three data sets: tornadoes (2003–2014) categorized by convective mode, false alarms (2012–2016) categorized by convective mode, and eleven interviews of NWS forecasters. The CWAs had no significant difference in mode frequency when removing replication from multiple-tornado events. However, when outbreaks were included, discrete supercell and QLCS signals were identified in MEG and OHX, respectively. Convective mode, season, and time of day were strongly associated. Tornadic discrete supercells followed a traditional severe weather pattern of spring and daytime occurrences and caused fewer false alarms. More QLCS tornadoes happened at night and in winter. Cells in lines and clusters accounted for larger proportions of events in the false-alarm data set than the tornado data set. Forecasters noted challenges in detecting tornadoes in convective modes other than discrete supercells, including short-lived QLCS tornadoes. Key forecaster concerns other than convective mode included storm speed, outbreaks, and lack of ground-truthing at night. Forecasters differed in their motivation to either warn on every tornado or avoid false alarms. Key Words: climatology, false alarm, QLCS, supercell, tornado.


MANKIND has always been fascinated by dreams. As might be expected, there have heen many attempts to assign a purpose Or significance to them. Although we dream for one or two hours every night, we do not remember most of our dreams. Earlier thinkers, such as Freud, did not know this. Modern theories (not reviewed here in detail) have usually proposed that sleep and dreams save energy or have various restorative functions, either to replenish the brain biochemically in some way, or to reclassify or reorder the information stored in it. Sleep is of several kinds. Dream sleep, or rapid eye movement (REM) sleep, is predominantly found in viviparous mammals and birds. It seems to be associated with homeothermy (a constant internal temperature) and the possession of an appreciable neocortex or its equivalent. It is not unimportant because of the appreciable amount of time we spend in this Peculiar state. We propose here a new explanation for the function of REM sleep. The basis of our theory is the assumption that in viviparous mammals the cortical system (the cerebral cortex and some of its' associated subcortical structures) can be regarded as a network of interconnected Cells which can support a great variety of modes of mutual excitation. Such a system is likely to be subject to unwanted or 'Parasitic' modes of behaviour, which arise as it is disturbed either by the growth of the brain or by the modifications produced by experience. We propose that such modes are detected and suppressed by a special mechanism which operates during REM sleep and has the character of an active process which is, loosely speaking, the opposite of learning. We call this 'reverse learning* or 'unlearning'. This mechanism, which is not the same as normal forgetting,


Tailor-made esters are becoming more widely used as either synthetic base stocks or performance additives for producing, for example, premium-grade synthetic or semi-synthetic speciality greases, aviation lubricants, or metal-working fluids. The present work, using a laboratory batch autoclave to evaluate the kinetic parameters, considers the kinetics of a typical non-catalytic esterification of a suitable polyol at elevated temperatures (190-220°C) and corresponding vapour pressure. The proposed rate equation represents satisfactorily the progress of the reaction.


Abstract: Sufficient conditions in terms of the coefficient sequences for the oscillation and asymptotic behaviour of nonoscillatory solutions of a class of second order nonlinear neutral difference equations have been obtained. The results improve some of the earlier results in the continuous case. 2000 Mathematics Subject Classification: 39A10, 39A12.


Summary
The uptake and utilization of [14C]sucrose, [14C]glucose and [14C]fructose by mature and immature potato tuber slices was studied. Both tissues absorbed [14C]glucose faster than [l4C]fructose but once absorbed, the hexoses were utilized similarly. In contrast, the greater part of the labelled sugars formed on administration of [14C]sucrose was sequestered at sites separate from the metabolic centres. Sucrose was taken up from the medium against a concentration gradient and transferred to metabolically inactive storage compartments without being hydrolysed either at the cell surface or at any stage during transit.


The detection and classification of vehicles on the road is a crucial task for traffic monitoring. Usually, Computer Vision (CV) algorithms dominate the task of vehicle classification on the road, but CV methodologies might suffer in poor lighting conditions and require greater amounts of computational power. Additionally, there is a privacy concern with installing cameras in sensitive and secure areas. In contrast, acoustic traffic monitoring is cost-effective, and can provide greater accuracy, particularly in low lighting conditions and in places where cameras cannot be installed. In this paper, we consider the task of acoustic vehicle sub-type classification, where we classify acoustic signals into 4 classes: car, truck, bike, and no vehicle. We experimented with Mel spectrograms, MFCC and GFCC as features and performed data pre-processing to train a simple, well optimized CNN that performs well at the task. When used with MFCC as features and careful data pre-processing, our proposed methodology improves upon the established state-of-the-art baseline on the IDMT Traffic dataset with an accuracy of 98.95%.


Immediately after the outbreak of coronavirus disease(COVID-19) in 2020, the Japanese government issued a non-legally binding administrative guidance to restaurants, requesting them to refrain from operations. The government did not need to compensate the restaurants for their temporary closure based on their voluntary actions.
In 2021, the statute against COVID-19 was amended to include administrative penalties for those who violate self-restraint requests; it was argued through social networking services that compensation under the property rights provision was necessary. Constitutional jurisprudence holds that compensation is not necessary to the extent that it is tolerated in the social life of citizens in general. It is possible that compensation would be necessary if society's evaluation of compensation for property rights changes significantly and the public reaches a consensus on these changes.
Even if compensation based on property rights is not necessary, provisions based on social rights can be used to require the government to take steps in parliament and governance to help the socio-economically vulnerable. Both the debates on whether compensation is necessary or unnecessary give a scathing assessment of the negligence of the political branches. When constitutional scholars argue that compensation for property rights is unnecessary, they should be careful as citizens may misunderstand that socioeconomic support based on social rights is also unnecessary.
Based on this analysis, this manuscript examines the damages caused by the COVID-19 vaccination. In Japan, the Constitution and the Local Autonomy Act place regular vaccination of citizens as a municipal task. If a disaster occurs that is beyond the jurisdiction of the municipality, the prefectural government, which is positioned above the municipality, responds. The central government is constitutionally responsible for coordinating prefectures in the event of a disaster that exceeds their capacity to handle. In response to the delay in the COVID-19 vaccination, the central government is trying to shift citizens' criticism of the delayed response to the vaccination onto local governments.
There existed a lower court decision that compensation under the property rights provision could be applied if the vaccination caused serious damage to the health or life of citizens. However, an interpretation that uses the compensation provision for property rights may lead to the conclusion that it is acceptable for the government to infringe on matters of life and health if monetary compensation for property rights is provided. Therefore, the Supreme Court has recognized the government's liability, judging that negligence exists in the system of vaccination itself in the obligation of doctors to question patients during vaccination when serious damage to health or life occurs due to vaccination. This decision would also apply to adverse reactions caused by COVID-19.

We can look to the future from our past experiences. This paper seeks to show that the experience of the Far East cases involving vaccination can be useful in other countries.
In Japan, based on the Vaccination Act, vaccinations were once required to be administered en masse in groups, and serious adverse reactions to life and body caused by vaccinations occurred at a certain rate. Since no remedy existed in the law for the lawful acts of public officials without negligence, the courts initially attempted to use compensation under the property rights provisions to remedy those whose lives or health were seriously damaged by vaccination. Among the academic theories, there was an opinion that Article 29(3) of the Constitution, compensation for special sacrifices of property rights, should of course be applied to violations of life and health. Others argued for using the provision on the right to life in social rights or the provision on the right to pursue happiness in Article 13. If the law enacted by the parliament was inadequate, they tried to make relief for the victims a new right under the constitution.
The Tokyo High Court presumed negligence on the basis that the doctor had a duty to check the patient for fever and other symptoms and exclude those who were contraindicated from the vaccination. In other words, the Tokyo High Court pointed out the flaws in the vaccination system itself, rather than the subjectivity of the doctors in charge of vaccination, because there will always be victims when vaccination is mandatory. The Supreme Court also emphasized the importance of providing relief to victims and decided to allow claims under the State Redress Act. In line with the decision of the Supreme Court, the Vaccination Act was revised, and the vaccination was changed from a mass mandate to an individual choice. A remedy system under the Vaccination Act has been prepared. Some academic theories consider this as an embodiment of new rights under Article 13 and social rights under Article 25 of the constitution.
Vaccination for COVID-19 is classified as TEMPORARY Vaccination under the Immunization Act, not routine vaccination. The central government is trying to blame the citizens' criticism on local governments. However, the cause of the delay lies with the government. The existence of three different systems for vaccines has placed a heavy burden on municipalities to enter information on citizens who have been vaccinated. Even if the vaccine is administered, if there is a delay in entering the information, the number of people vaccinated is assessed as low in the data.
The delay was originally caused by political negligence that delayed the development of laws for vaccination, and a claim for damages under the State Redress Act for the government's inaction could theoretically be considered.
In preparation for the case of damage caused by vaccination, the MHLW is supposed to take necessary measures for the proper implementation of vaccination, such as collecting symptoms suspected of adverse reactions occurring after vaccination, reporting these symptoms to the Health Sciences Council, listening to its opinions, and providing information on the safety of vaccination.


The energy services industry in China is still in the early stage of development, and it's the size of the industry as well as the existing service level is not enough to meet the diverse needs of the market, and the current industry value chain system is not perfect enough. This paper first analyzes the main elements of the energy service industry and its main body behavior, and further sums up the value link between the various subjects; Secondly, based on the modular and value network theory, the construction of energy service industry value network, the main purpose is to increase the understanding of the energy service industry value network and operational mechanism. The results show that the energy service industry value network is different from the traditional value network system. Under the impetus of the modularization trend, the multi-service module main body, the division of labor and cooperation among the major modules, effectively integrated into the industrial value network to achieve value creation and maximize value.


. Patients with a hereditary myopathy with paroxysmal myoglobinuria were studied in the chronic state of the disease. They were characterized by muscle contractions of fairly normal strength and quite good endurance in exercise with small muscle groups, but a poor physical performance in exercise of some duration with large muscle groups.

Several facts indicate that it was not muscular weakness, but the circulatory capacity that was a main factor limiting the physical working capacity in exercise of some duration with large muscle groups. The oxygen uptake was largely normal in relation to the work performed. However, even light exercise on a bicycle ergometer caused tachycardia (approaching maximum heart rate), a high cardiac output (approaching, for the size of the individual, maximum values in the normal range) and an abundant blood flow through the exercising legs. Thus, there were no signs of insufficient heart function, but the utilization of the oxygen of the blood in the exercising limbs was low.

The concentration of lactate, and particularly of pyruvate, in the blood, and the lactate and pyruvate production increased more than in the controls for the slight work performed. During exercise the lactate/pyruvate ratio decreased and the calculated "excess of lactate" was negative, while it increased in normal subjects. After exercise the excess lactate was higher in the patients than in the controls. This indicates an abnormal muscle metabolism, probably a decreased capacity for pyruvate oxidation.

It is suggested that a metabolic disturbance caused an abnormally large production of metabolites in the working muscles, resulting in muscular vessel dilatation by a local humoral effect. The muscles acted almost like a-v shunts and, as a consequence, the patients had a hyperkinetic circulation, i.e. a low O2 uptake in relation to cardiac output, a low a-v O2 difference for mixed venous blood and for the venous blood of the exercising limbs.


Injury or disease of the brain can be troubling and resource laden in a hospital care setting. When the patient is discharged they are often released to unprepared and untrained family members who may be overwhelmed with the responsibility and burden of care. Local medical providers may not be aware of simple tools that family members and the patient themselves can use to encourage healthy monitoring, communication and recovery strategies. The patient may not reason or function as they did before the injury and this can change family dynamics and influence quality of life at home and in the community. Diligent and knowledgeable follow up can decrease post discharge complications and aid patient recovery. Here we offer suggestions for care and monitoring adaptable for low resource settings.


The measured thermal response of generic objects in engulfing pool fires is presented. The objects include cylinders and flat plates of various sizes and materials. A simple radiation/convection model of the heat transfer from the fire to the object is developed and discussed in light of the experimental data. 11 refs., 20 figs.


In this position paper, we argue that in the context of a user's interaction with multiple platforms, consistency must be supported along with support for user's task migration. We believe that the user should be able to perform a task using multiple user interfaces through an application that may or may not be similar at the interface level on each platform but, more importantly, one that supports seamless task migration. Further, we believe that consistency is desirable as long as it supports seamless task migration but should not dictate the design. We present examples of how successful multiple user interfaces have tackled the issue of consistency and discuss examples of why we should support task migration as a higher goal than consistency. We present a definition of task disconnect and its relationship to task migration. We also discuss some design issues related to consistency and task disconnect that must be considered in the development of multi-platform user interfaces.


HarassMap is an Egyptian organisation that works to create an environment where sexual harassment is not tolerated, and where individuals and institutions take action against it. For the purpose of this project, the project team cleaned up, organised, and made openly available for the public to access and use through a web portal, three main types of data: • Crowdsourced reports of sexual harassment incidents (reports on HarassMap's online reporting and mapping system) CSV and XLS • Field data from HarassMap's research on sexual harassment using traditional qualitative and quantitative research methods DOCX, PDF, SAV, MP3 • Social media conversations (comment threads and messages related to sexual harassment on harassMap's Facebook page) XLS The social media data was collected retrospectively from our Facebook page during the project period and covers the period 2010-2016. The crowdsourced data and the research data was cleaned and organised to make sure it is usable for the public but still kept in its raw format. During the collection and organisation period, we also made sure to clear out all personal identifiers from the data to ensure anonymity and confidentiality, and prepared descriptions of each dataset that will help the public understand how the data was collected and how it can and cannot be used. The data is stored online on a web portal that we built together with a web developer during the project period. On the web portal, the data is available for the public to view, search and download for research or other purposes. The data is also backed up on a hard drive ‡ © Wael R. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. and the cloud. The web portal and HarassMap open data will be advertised on our website, and the direct link shared with our contacts and others who approach us with interest in our data.


Deactivation of G-protein-coupled receptors relies on a timely blockade by arrestin. However, under dim light conditions, virtually all arrestin is in the rod inner segment, and the splice variant p44 (Arr1–370A) is the stop protein responsible for receptor deactivation. Using size exclusion chromatography and biophysical assays for membrane-bound protein-protein interaction, membrane binding, and G-protein activation, we have investigated the interactions of Arr1–370A and proteolytically truncated Arr3–367 with rhodopsin. We find that these short arrestins do not only interact with the phosphorylated active receptor but also with inactive phosphorylated rhodopsin or opsin in membranes or solution. Because of the latter interaction they are not soluble (like arrestin) but membrane-bound in the dark. Upon photoexcitation, Arr3–367 and Arr1–370A interact with prephosphorylated rhodopsin faster than arrestin and start to quench Gt activation on a subsecond time scale. The data indicate that in the course of rhodopsin deactivation, Arr1–370A is handed over from inactive to active phosphorylated rhodopsin. This mechanism could provide a new aspect of receptor shutoff in the single photon operating range of the rod cell.


A practical framework - understanding knowledge management document imaging and management - taming the paper tiger groupware - messaging and co-operation developing effective knowledge with both qualitative and quantitive research systems architecture - the preparation for knowledge management the storage and access of distributed knowledge an integrated development model for knowledge management the role of directories in knowledge management the Internet as a mechanism to enhance content and extend access to corporate data resources the power of managing knowledge in a worldwide enterprise knowledge management for competitive advantage - mining diverse sources for marketing intelligence building knowledge communities with webs of connections.


Under acidic conditions, monodisperse micron sized mesoporous silica which had an about 1.4 μm diameter, was synthesized by hydrothermal method using F127 (EO106PO70EO106) as template and tetraethoxysilane (TEOS) as silica source. The surface area and pore volume were determined by nitrogen adsorption method, and the diameter of the mesoporous silica was obtained by field-emission scanning electron microscopy. Then the mesoporous silica was used firstly as a carrier for the immobilization of β-galactosidase from aspergillus oryzae, under the optimum conditions, the enzyme activity and the activity yield were 355.29 U/g and 63.11%, separately. Meanwhile, the fundamental properties of the immobilized enzyme, such as the influences of temperature and pH, were assayed and valuable results were obtained.


The fundamental concept in an IWSN-based Healthcare Environment is that doctors' devices can directly access the data from a patient's sensor in real-time. Unfortunately, wireless-based communication between the doctor's device and the patient's sensor is vulnerable to attacks such as impersonation, tracking, DoS, and cloning attacks. Therefore, this article tries to resolve the security problems in an IWSN-based Healthcare Environment by developing a secure authentication protocol using biometric and PUF -based. In addition, the informal use of solid reasoning analysis and formal analysis using the scyther tool proves that our protocol achieves security features and withstanding well-known attacks.


This passage analyzes the aesthetic isomorphism of Zen poems, tea and Simple landscape and further develops the core of why the aesthetics has its strong vitality, from the aspects of the relationship of the mutual development of the three and the influencing factor of them. And on this basis, this passage analyzes the isomorphism of the three based on the ideology and forms. This passage expects to build a bridge of the different forms of Zen aesthetics and to explore the law of the common aesthetic feeling that surpasses history and forms so that we can pave the way for the research of the Zen aesthetics afterwards and bring in more inspirations.


In the last years, the popularity of deep learning techniques has renewed the interest in neural models able to process complex patterns, that are naturally encoded as graphs. In particular, different architectures have been proposed to extend the original Graph Neural Network (GNN) model. GNNs exploit a set of state variables, each assigned to a graph node, and a diffusion mechanism among neighbor nodes, to implement an iterative state update procedure that computes the fixed point of the (learnable) state transition function. In this paper, we propose a novel approach to state computation and learning for GNNs, based on a constraint optimisation task solved in the Lagrangian framework. The state convergence procedure is implicitly expressed by the constraint satisfaction mechanism and does not require a separate iterative phase for each epoch of the learning procedure. In fact, the computational structure is based on the search for saddle points of the Lagrangian in the adjoint space of weights, neural outputs (node states), and Lagrange multipliers. The proposed approach is compared experimentally with other popular models for processing graphs.