This study presents an analysis of school-based mentors' experiences and preparedness in supervising student teachers on teaching practice in Zimbabwe. The strategy employed was concurrent triangulation because it enabled the researcher to use both quantitative and qualitative methods of data collection concurrently. The population comprised 14 universities, 3 secondary teachers' colleges. The informants comprised 100 heads of schools, 560 lecturers involved in teaching practice, 1120 schoolbased mentors and 7200 current and former student teachers. The sample was selected through purposive sampling procedure. The sample comprised 3 universities, 2 teacher training colleges, 25 heads of schools, 75 lecturers, 250 schoolbased mentors and 200 current and former student teachers. The study was carried out in Zimbabwean universities and teacher training colleges between June 2012 and November 2013. The methods of data collection used were content analysis, interviews, questionnaires and focus group discussions. The heads of schools and schoolbased mentors were interviewed. Qualitative data collected was analysed using the constant comparative approach and cross case analysis. Quantitative data collected was analysed using the descriptive statistics through the conversion of figures into percentages. The findings revealed that the school-based mentors were not helpful in assisting the student teachers in developing teaching or pedagogical skills .There was no collaboration between the schools and the Original Research Article British Journal of Education, Society & Behavioural Science, 4(11): 1476-1488..., 2014 1477 teacher training institutions and this reflected ineffective mentoring practices and mentoring relationships. The researcher recommends teacher training institutions to design a participatory training programme with school–based mentors and student teachers for effective development of pedagogical skills.


Thermotropic main-chain liquid crystalline ionomers were synthesized from isosorbide,sebacoyl chloride and brilliant yellow by interfacial condensation reaction.The structure of polymers was characterized by infrared spectroscopy(FT-IR),the liquid crystal properties were characterized by POM,DSC and X-ray.The results show that the ionomers are monotropic smectic A thermotropic mesophase;the mesophase properties and the type of polymers are not affected by the addition of ion element brilliant yellow.


Low bond yields and the prospect of rising rates have the potential to trip up yield-focused stock and bond investors.


There are three types of faults in Block T121-4 of Aonan Oilfield, among which the faults developed from the early Qingshankou and terminated in the Third member of Nenen are the main channels for oil-gas migration. The pre-stack inversion shows that the lame impedance slice can well reflect the reservoir morphological characteristics and the channel characteristics are obvious. During the deposition period from HIIto HI, the water body changed from deep to shallow, the sedimentary facies transitioned from lakes to deltas, and underwater shunt channels were favorable reservoirs. The formation testing results show that the distribution of oil-gas is closely related to faults and sand bodies, and is the main controlling factor of reservoir formation. The main methods of oil-gas migration are vertical migration and short- distance lateral migration. If the fault-sand coupling relationship is good, oil-gas accumulation can be obtained. The reservoir anatomy shows that there are mainly two types of reservoirs in Heidimiao reservoir in the study area, namely structural reservoir and structural lithologic reservoir.


Summary : The development of ICT's and their associated uses raises the question as to how these can tie in with the notion of sustainable development. Although the most common approach consists in examining the possible impacts of ICT development in economic, social and environmental terms, the ability of information processing and communication technologies to be integrated within these three dimensions has still to be explored. Taking the notion of territory into consideration would seem to be a suitable way of answering this question. This is how two research teams came to exchange synergies and work together on a comparative analysis of the logic behind the installation of networks and the development of uses in the Maurienne and Vesubie valleys. This article presents the first results of the research programme, following identifi- cation of a certain number of challenges stemming from the links between ICT's and sustainable development and a brief characterisation of the geographic area. These results underline the importance of meshing given the smaller level of investment in the area of ICT uses. However, specific uses do emerge in certain conditions, which lead to the offering and possible mobilisation of resources specific to the territories. The ability of territories to break free from the control and influence of external actors would explain the emergence of such uses. From being seen as generic resources needed to develop territories, ICT's have acquired the status of resource operators. This status has yet to be characterised.


Based on q-expected entanglement measure for q⩾1 , we generalize the polygamy inequality for multiparty entanglement in arbitrary-dimensional quantum systems. By using the βth-power of the q-expected entanglement of assistance for 0⩽β⩽1 and the Hamming weight of the binary vector related with the distribution of subsystems, a class of weighted polygamy inequalities in arbitrary-dimensional quantum systems is established. We further demonstrate that our class of weighted polygamy inequalities can be improved even into tighter inequalities, under some conditions, with auxiliary entanglement in bipartite subsystems. Our results may provide new ideas for studying the polygamy constraints of multiparty entanglement and better characterizing the entanglement distribution.


In this study, a new two-dimensional (2D) direction-of-arrival (DOA) estimation method with L-shaped array is proposed based on the sparse representation framework. The basic idea is to transform the 2D DOA estimation problem into two one-dimensional DOA estimation problems by introducing a new compound electric angle. The compound electric and elevation angles are estimated through solving two sparse recovery problems subsequently. Then the azimuth angle estimation and the angle pairing process are completed simultaneously based on the relationship between the estimated elevation and compound electric angles. Owing to the exploitations of the sparse representation technique and the cross correlation information of the incident signals, the proposed method exhibits a superior performance, including higher angle resolution ability and improved robustness against low signal-to-noise ratio or small number of snapshots, as well as not requiring the knowledge of the source number. Numerical simulations are performed to verify its effectiveness.


Trident was one of the four Discovery-class Step-1 mission proposals selected by NASA in 2020 for further development and study; however, in 2021, the Step-2 proposal was not down-selected to transition into the next phase of mission development, i.e., a mission for flight. Neptune's largest moon, Triton, was the primary focus of study for Trident. Triton's physical and orbital characteristics make it a unique planetary target for scientific exploration, providing opportunities for investigations in a wide variety of scientific fields, including geomorphological, atmospheric, geophysical, magnetospheric, and ionospheric studies. The science objectives of the Trident mission encompassed an in-depth interior-to-exterior set of objectives, focused on multiple outstanding questions resulting from the 1989 encounter of Voyager 2, and subsequent analysis. Ball Aerospace Corp. was tasked with building the Trident spacecraft, with JPL responsible for providing Engineering Support (Mission Design & Navigation, Mission Planning, Flight Operations, Ground Data Systems, Systems Engineering) and leading Project Management. The observatory would carry a wide-ranging suite of scientific instruments onboard, including an Infrared Spectrometer (IRS) and Narrow Angle Camera (NAC) to be provided by Ball Aerospace Corp., a Wide Angle Camera (WAC) from JPL, a Magnetometer from UCLA, a contributed Plasma Science Suite from IRF (Sweden), and a contributed Radio Science instrument from ASI (Italy). All of these instruments would be used to collect unique datasets during the Triton encounter. Trident would have taken advantage of an ~13-yr, nearly-ballistic trajectory to Triton, utilizing a timely Jupiter Gravity Assist, to execute a 10-day long encounter in the Neptunian system. Launch was planned for October 2025, with Triton arrival scheduled for December 2038. The timeline for this mission would have been sub-divided into seven major phases: Launch, Commissioning, Inner Planet Cruise, Outer Planet Cruise, Approach, Encounter, and Science Data Return. Multiple planetary flybys were planned to be performed during the cruise, including three Earth flybys and one Venus flyby in the Inner Planet Cruise phase, and one Jupiter flyby in the Outer Planet Cruise phase. Along with conventional (Range and Doppler) tracking data, Delta-DOR and Optical Navigation data were also to be acquired to assist with spacecraft navigation during the Approach and Encounter phases. A 3 meter X-Band High Gain Antenna would allow playback of all science data at 1 kbps within 1 year after the Triton Encounter. The Mission Planning element on Trident encompassed and informed multiple aspects of this proposal, ranging from science observation planning during the Triton Encounter phase, to generation of activity timelines for all mission phases; performing ground coverage analysis for science observations to be acquired by all instruments and tracing them to science requirements; evaluation of spacecraft resources including data volume stored onboard, power/energy consumption, telecom (commanding/telemetry) requirements, and overall, working at the interface of science and engineering teams on the mission. All of these functions that were performed by the Mission Planning team on this proposal are discussed in this paper.


MARCH 2018 ■ IEEE INDUSTRIAL ELECTRONICS MAGAZINE 3 T raditionally, the first issue of IEEE Industrial Electronics Magazine (IEM) every year puts a spotlight on the IEEE Industrial Electronics Society (IES), its members, and its organization. The beginning of the new year is when important changes in the Society take effect, when the terms of new officers start, and when we welcome new Administrative Committee members. Toward the end of the previous year, the new IEEE Fellows are announced, and, at our flagship conference, the IES Annual Conference (IECON), we present the prestigious Society awards to merited members of the IES. As we start 2018, it is therefore appropriate that we commemorate the invaluable contributions of the people who make our Society strong in technical and organizational respects. This first issue of IEM is a good opportunity to give them the recognition they deserve. Indeed, there is exciting news to report. This month's issue is the first under the presidency of Prof. Xinghuo Yu, who took office at the beginning of the year. In his message, he shares his thoughts on industrial electronics not only for our technical IEEE Society but also for what it can bring to society in a broader sense. One of his key insights it that there is nothing to gain by thinking in simple terms; it is neither applied versus fundamental research, nor is it academia versus industry. Only a balanced mix of all of these approaches brings real innovation. This issue also establishes a new column, "Women in IES News," with Prof. Lucia Lo Bello as the associate editor. Sadly, despite many attempts to improve the situation, women are still grossly underrepresented across all engineering disciplines. Promoting women in engineering (WiE) has been a prominent activity within the IEEE and the IES for many years. In 2017, a new initiative began with a dedicated and highly successful workshop at IECON. This new column will give a voice to women engineers, their activities, and the initia tives run by them to en courage their active participation in the IES, with or without the WiE umbrella within the IEEE. As for the technical content of this issue, the common denominator of the feature articles is the use of information technology for modern, distributed automation systems in different application domains. "To Centralize or to Distribute: That Is the Question," by Z. Cheng, J. Duan, and M.Y. Chow, investigates the next generation of microgrids and how to control them. Microgrids can be seen as confined entities with certain autonomy within a smart grid. While they were previously considered from the perspective of stability in the event of disconnection from the grid, advanced microgrids can achieve energy generation and consumption balancing internally and, therefore, behave as autonomous parts of the grid. Coordination of these entities is a longstanding problem, and this article reviews classical centralized approaches versus distributed concepts, finding that the latter are advantageous in terms of scalability, reliability, and resilience. The article "Industrial Cyberphysical Systems," by B. Cheng, J. Zhang, G.P. Hancke, S. Karnouskos, and A.W. Colombo, looks at the value of modern cloud computing technologies in an industrial context. The Internet of Things, with massively connected devices together with cloud solutions, allows for the collection and storage of enormous amounts of data. Pure technological prerequisites are, however, only one aspect. A much more interesting question is what to do with these data, i.e., how to analyze and interpret them within the possibly short time frame given by industrial control and decision-making systems. This article reviews architectural issues, existing frameworks, and industrial alliances driving the evolution of big data handling in industrial applications. The "Historical" column, "Solidifying Power Electronics," reviews the development of solid-state devices that are the foundation of modern power electronics. A large part of what constitutes the technical scope of the IES would be unthinkable without these devices, which convert electric power from dc to ac and vice versa. Last but not least, we also honor the recipients of the 2017 IES Awards, and we present the 15 IES Members who recently became IEEE Fellows. Congratulations to all of them and all of the award winners! New Horizons


Technical difficulties in the deployment of a Wallstent biliary endo-prosthesis may be encountered in situations where increased friction forces interfere with the smooth withdrawal of its covering membrane. Examples of such situations are stenting of left-sided and very tight strictures and deployment of two or more stents lying parallel to or overlapping each other. We describe a new technique using an 8F peel-away introducer sheath, which reduces the resistance caused by friction during the release of an endoprosth-esis. The technique has the additional advantage of allowing easy advancing or removal of a partially deployed stent. This technique was successfully and safely used in 35 complex stenting procedures, which were carried out in 25 patients with mostly hilar strictures. Only two significant complications occurred (one haemobilia and one septicaemia), unrelated to the use of the sheath.


categories on the basis of size and color. The largest seedlings approached in size and color those which had been given both N and P and their roots contained nodules about an inch in diameter, and several smaller ones of assorted sizes. The smallest plants were chlorotic in a fashion typical of nitrogen deficiency in many plants with the leaves yellow-green. The roots had several minute nodules but no large ones. The seedlings intermediate in size had nodules about a half inch in diameter and foliage of a pale-green coloration. In Table 3 are given the average dry weights of roots per plant and the distribution of root nodules according to treatment and size class. The appearance of roots bearing nodules is shown in the photograph. Of special interest is the large nodule joining the roots of the two plants. Through careful slicing of this nodule it became apparent that it grew on one plant but enveloped the root of the other. The dry weights showed that plants supplied with N + P had the largest root system and no nodule formation. Of the plants supplied with only P, the ones with the best nodule development produced the most root weight. On wildland soils low in nitrogen it would be well to manage for those species which increase fertility. It appears that western mountain mahogany is capable of improving the nitrogen status of low fertility soils.


Twitter: @oreillymedia facebook.com/oreilly Asynchronous JavaScript is everywhere, whether you're using Ajax, AngularJS, Node.js, or WebRTC. This practical guide shows intermediate to advanced JavaScript developers how Promises can help you manage asynchronous code effectively—including the inevitable flood of callbacks as your codebase grows. You'll learn the inner workings of Promises and ways to avoid difficulties and missteps when using them.


Introduction: Malignant pleural mesothelioma is a rare tumour commonly associated with asbestos exposure however with increasing incidence and poor survival. The standard first-line chemotherapy regimen is the combination of cisplatin and pemetrexed, with median overall survival of 13 months. Other therapeutic options like surgery, radiation and immunotherapy are currently limited therefore patient s performance status and histological subtype are the only prognostic factors (Scherpereel A. et al. EurRespir J 2010;35: 479-95, Scherpereel A. EurRespir J.2017 Mar 15;49(3). Aim and Objectives: The aim of study was to compare the patient9s survival depending on whether they received chemotherapy or not. Methods: We identified retrospectively 24 patients diagnosed with pleural mesothelioma in Department of Pulmonology, Clinical Hospital Center Split, Croatia evaluating their management, whether they were treated by cisplatin/pemetrexed or solely palliative care as a result of poor performance status or refusal of any specific treatment. Kaplan-Meier survival analysis was used (MedCalc Software ver. 18). Results: The overall median survival (OS) time was 14,6 months. A pronounced OS benefit for palliative care versus cisplatin/pemetrexed was observed, 17 vs 8 months, respectively; HR, 0,3665 ; 95% CI, 0,14 to 0,90 ; P = 0,0047, Fig. 1. Conclusions: Chemotherapeutic treatment did not show better outcomes than solely palliative treatment. Future prospective randomized controlled studies are necessary to optimize the treatment of malignant mesothelioma.


Research devoted to development of processes for the isolation of protactinium and for the removal of fission products from molten-salt breeder reactors is reported. During this report period, engineering development progressed on continuous fluorinators for uranium removal, the metal transfer process for rare-earth removal, the fuel reconstitution step, and molten salt-- bismuth contactors to be used in reductive extraction processes. The metal transfer experiment MTE-3B was started. In this experiment all parts of the metal transfer process for rare-earth removal are demonstrated using salt flow rates which are about 1 percent of those required to process the fuel salt in a 1000-MW(e) MSBR. During this report period the salt and bismuth phases were transferred to the experimental vessels, and two runs with agitator speeds of 5 rps were made to measure the rate of transfer of neodymium from the fluoride salt to the Bi--Li stripper solution. The uranium removed from the fuel salt by fluorination must be returned to the processed salt in the fuel reconstitution step before the fuel salt is returned to the reactor. An engineering experiment to demonstrate the fuel reconstitution step is being installed. In this experiment gold-lined equipment will be used to avoid introducing productsmore » of corrosion by UF$sub 6$ and UF$sub 5$. Alternative methods for providing the gold lining include electroplating and mechanical fabrication. (JRD)« less


The various size and shape of cracks in concrete induce deterioration of reinforced concrete structures including nuclear power plants. The wider and deeper the crack is, the concrete structures are more vulnerable to carbonization. Thus, it is essential


Cross-cultural marketing of consumer products and services has become an integral part of the mainstream strategic thinking of multinational consumer products firms. These firms must increasingly address ecological concerns of the individuals comprising the various global market segments where these products will be marketed. Green Marketing has thus become a hot topic for both producers and consumers across cultures. This study investigates how consumers across cultures feel about the environment, whether it makes sense to stress green marketing to consumers in other cultures if they are not environmentally sensitive, and whether there are rudimentary differences in ecological attitudes based on cultural origins. The paper compares consumer attitudes toward the environment to determine whether major differences do exist among cultures. Sample data of 459 consumers was gathered from five countries (Azerbaijan, Italy, Spain, the United States and Venezuela) and was analyzed. Factor analysis was performed to indicate dimensions of environmental responsibility. ANOVA was used to see if differences exist between cultures with regard to the various dimensions. Environmental responsibility is characterized by awareness of environmental problems, knowledge of remedial alternatives best suited to alleviate those problems, skills needed to pursue those actions, and a possession of a genuine desire to act.


We study the inhomogeneous chiral condensates in the proximity of the chiral tricritical point (TCP) of two-flavor QCD. Deriving the Ginzburg-Landau (GL) functional up to the eighth order in the order parameter and its spatial derivative, we explore off the TCP and find that critical curves are bent by non-linear effects. In the newly extend GL coupling space, we find the TCP being realized as a multicritical point where five independent critical lines meet up. We also present general analyses for the energies associated with several higher dimensional crystal structures.


Embodiments of the present invention provide an improved surgical instrument ready with several improvements and advantages over the prior art. The surgical instrument has an end effector that is able to perform various operations, including the collection, cutting and sealing and / or coagulating tissue, wherein one of the operations is controlled by a handle which is movable relative to the instrument, to move the end effector between two states. The present invention provides a simplified latching mechanism for this movable handle. In concrete terms, the latching mechanism composed of a single integrally formed component, which is arranged to move with the handle in engagement so that the end effector is held in a state whereby the user has one hand free to perform other functions of the instrument. In use, a user can thus use the surgical instrument to capture tissue between the end effector by the end effector is activated using the handle, and then use the locking mechanism to snap the handle in the Endeffektoraktivierungsposition, so that the surgeon can remove his hand from the handle and perform another task.


Hand pose estimation plays an important role in human-computer interaction. The traditional way is to deal with a single frame image. We know that the gesture is continuous, so the adjacent frames must be highly correlated. Therefore, the input of model of this paper was changed from single frame image to multi-frame images in order to use the condition that the adjacent frames have relevance. So the structure of CNNRNN was used in this paper. We discussed the effect of using the RNN module in the model. Finally, we demonstrated that our approach significantly outperforms state-of-the-art techniques in the NYU dataset.


Reflection on the variety of forms of social life has long been a source of moral skepticism. The thought that there are many radically different social systems, each of which colors the way its members think about moral and political questions, has been thought by many moral philosophers to undermine confidence in our belief that our way of looking at-or even posing-these questions is the correct one. The fact of cultural variety is held to reduce, if not eliminate altogether, the possibility of moral criticism of the practices of other societies. This thought is not a recent one; it is implicit, for example, in an observation made in David Hume's "A Dialogue," when he writes: There are no manners so innocent or reasonable, but may be rendered odious or ridiculous, if measured by a standard, unknown to the persons; especially, if you employ a little art or eloquence, in aggravating some circumstances, and extenuating others, as best suits the purpose of your discourse.


There are two important approaches based on linear ranking functions for solving linear programming problems with cost coefficients as an auxiliary problem to obtain a fuzzy solution of fuzzy variable linear programming problem. The first approach uses the primal simplex method that assumes an initial primal feasible basic solution is at hand. The second approach is based on dual simplex method that begins with a basic dual feasible basic solution and proceeds by pivoting through a series of dual basic solutions until the associated complementary primal basic fuzzy solution is feasible. In this paper, we propose a new method called the primal-dual algorithm, which is similar to the dual simplex method and begins with dual feasibility and proceeds to obtain primal feasibility while maintaining complementary slackness. An important difference between the dual simplex method and the primal-dual method is that the primal-dual algorithm does not require a dual feasible solution to be basic. This algorithm is useful specially for solving minimum fuzzy cost flow problem in which finding an initial dual feasible solution turns out to be a trivial task.


Abstract Background: Hyponatremia is a common medical condition in the elderly. When encountering hyponatremia in the clinical setting, it is important to start with a broad differential list, and then work through all the different possibilities before arriving at the correct diagnosis. Treatment guidelines recommend starting with broad differentials in order to avoid premature conclusions, reach the correct diagnosis, and avoid suboptimal treatment or inappropriate workup. Clinical Case: 86-year old female presented with one week of general weakness, decreased appetite, sleep, and polyuria. Initial serum sodium was 128 mmol/L (136-146), and plasma and urine osmolarities were 271mOsmol/kg (285-305) and 592 mOsmol/kg (50-1400), respectively. Her urine sodium was elevated at 126 mmol/L (n<20), suggestive of a clinical picture of a syndrome of inappropriate secretion of antidiuretic hormone (SIADH). The patient did not respond to <1L/day fluid restriction alone. The initial dose of furosemide did not improve the sodium level; thus, the dosage was raised and salt tablets were added, which improved sodium level steadily. Meanwhile, her thyroid profile showed TSH 0.07uU/mL (0.3-4.2), free T4 0.9 ng/dL (0.8-1.8), demonstrating central hypothyroidism while taking levothyroxine as a home medication. Further pituitary workup revealed an abnormally low level of FSH 4.95mIU/mL (16.7-113.5) and LH 2.33mIU/mL (10.8-58.6), considering the post-menopausal state. Prolactin was elevated at 39ng/mL (3.3-26.7). The rest of the hormone labs including cortisol, ACTH, and GH were normal. Blood sugar and serum triglyceride levels were within the normal range. Per history and physical, the patient neither exhibited hypervolemic nor hypovolemic features. No home medications would have likely caused SIADH. Her MRI of the brain in 2016 reported a sellar mass uplifting the optic chiasm and its extension of the right cavernous sinus. Latest outpatient record from October 2020 documented pituitary macroadenoma with secondary hypothyroidism, secondary hypogonadism, and hyperprolactinemia due to the stalk effect. Finally, ADH returned as <0.8 pg/mL (0-4.7), ruling out SIADH as the most likely etiology. Conclusion: Treating hyponatremia in the elderly is a challenge. Starting with a broad differential list and effectively ruling out each diagnosis is critical to find the most likely etiology and prevent a premature diagnosis. Instances of such diagnoses and subsequent inappropriate treatments invariably lead to poor patient outcomes. It is, therefore, crucial to keep an open mind and consider all possibilities when approaching a hyponatremic elderly patient. References: Paul Grant, John Ayuk, Pierre-Marc Bouloux. The diagnosis and management of inpatient hyponatraemia and SIADH. Eur J Clin Invest 2015;45(8):888-894.


An analysis of a debate which took place in the Czech Republic in February-March 2017 after the Czech social democratic Prime Minister Bohuslav Sobotka proposed to increase taxes for "rich people" (i.e. those who earn more than £ 20 000 pounds sterling annually) and the public realised that there are only 9 per cent of such people in the country.


Myeloid cells represent a dominant cellular compartment of tumor lesions and play key roles in tumor inception, progression, metastasis, and response to treatment. Mononuclear phagocytes (MNPs), which include dendritic cells and macrophages, are unique among myeloid cells, as they not only shape both the broader composition and state of the tumor microenvironment but can also specifically instruct cancer-specific, T cell–mediated tumor cell killing, making them especially attractive targets for cancer treatment. Although MNPs remain difficult to modulate therapeutically, our understanding of MNP biology in the antitumor immune response has expanded significantly, offering hope for new possibilities in cancer immunotherapy. Here, we review the recent advances in our study of the cellular identity, molecular diversity, and spatial organization of MNPs in tumors, and we discuss the importance of tailoring therapeutic strategies to incorporate these new insights into cancer treatment design. Expected final online publication date for the Annual Review of Cancer Biology, Volume 7 is April 2023. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.


This chapter provides a detailed characterization of the various meanings of the term "divine hiddenness," carefully and rigorously articulates the version of the problem of divine hiddenness that has dominated contemporary philosophical discussion for the past twenty-five years, and then explains the relationship between that problem and the problem of evil.


Interest in collecting mileage fees for road usage is growing. However, the cost of collecting fuel taxes is relatively low, while the cost of collecting mileage fees appears to be quite high. There is relatively little actual experience with mileage systems, but information related to the cost of systems for heavy vehicles, experimental systems, and a proposed Dutch system provides a starting point for identifying the key cost components. This paper summarizes cost information from a variety of sources and identifies key areas for cost comparison.


The hydrothermal reaction of PdCl 2 with K 2 Se 4 in the presence of different KOH and water in the 1:5:5:40 ratio produced K 2 [PdSe 10 ] (I), the first metal polychalcogenide compound containing two interpenetrating three-dimensional frameworks. The black rectangular chunky crystals of I are insoluble in water and most organic solvents. They crystallize in the orthorhombic space group I2 1 2 1 2 1 .


The Solar System is a place full of mystery and wonder. It also lends itself to early years practical activities as Lesley Milmine explains.


This paper looks at the pathway educators and facilitators can take to build step by step successful programming,
effective reaching and learning and successful students. Based on actual classrooms and the learning journeys that ocurred
by using a social competency tied to interdisciplinary curriculum approach; this builds resilience and lifelong skills. It is
tied to authentic purpose and the real world


The involvement of intracellular Ca2+ stores and their regulatory mechanisms in mediating pituitary adenylate cyclase‐activating polypeptide (PACAP) stimulation of growth hormone (GH) and maturational gonadotrophin (GTH‐II) secretion from goldfish pituitary cells was investigated using a cell column perifusion system. Pretreatment with caffeine abolished the GH and GTH‐II responses to PACAP. Dantrolene attenuated PACAP‐elicited GTH‐II release but did not affect the GH response, whereas ryanodine and 8‐bromo‐cADP ribose did not alter PACAP‐induced GH and GTH‐II release. Two endoplasmic/sarcoplasmic reticulum Ca2+ ATPase (SERCA) inhibitors, thapsigargin and cyclopiazonic acid, augmented PACAP‐induced GTH‐II release; similarly, thapsigargin elevated GH responses to PACAP. Treatment with carbonyl cyanide m‐chlorophenylhydrazone, a mitochondrial uncoupler, reduced PACAP‐stimulated GH release; however, inhibition of the mitochondrial Ca2+ uniport by Ru360 did not affect GH and GTH‐II responses. The phosphatidyl inositol (PI)‐specific phospholipase C (PLC) inhibitor ET‐18‐OCH3 inhibited, whereas the phosphatidyl‐choline (PC)‐specific PLC inhibitor D609 enhanced, PACAP‐stimulated GH and GTH‐II responses. On the other hand, the IP3 receptor blocker xestospongin D had no effect on PACAP‐induced GTH‐II response and potentiated the GH response. These results suggest that, despite some differences between GH and GTH‐II cells, PACAP actions in both cell types generally rely on a caffeine‐sensitive, but a largely ryanodine receptor‐independent, mechanism. PC‐PLC and some SERCA negatively modulate PACAP actions but mitochondrial Ca2+ stores per se are not important. A novel PI‐PLC mechanism, which does not involve the traditional IP3/Ca2+ pathway, is also suggested.


Real-time synchronization is one of the essential theories in real-time systems, and the recent booming of parallel real-time tasks has brought new challenges to the synchronization analysis. As the easy implementation and negligible overheads, spin-locks have received much interest since the study for sequential tasks. However, existing spin-based blocking analyses for parallel tasks are relied on execution-time inflation, and the substantially more accurate inflation-free analysis has not been fathomed yet. Moreover, existing analyses suffer an overrepresentation problem, which can be further exacerbated for parallel tasks with spin-locks. To overcome such pessimism, we propose an improved blocking analysis for non-preemptive spin-locks based on a finer-grained shared resource model. In particular, we consider individual length for each shared resource request and use the state-of-the-art linear optimization technique to achieve a pinpoint inflation-free analysis. Empirical evaluations show that the proposed analysis dominated other state-of-the-art analysis, which further shows the improved accuracy achieved by the proposed approach.


This document contains Confidential, Proprietary and Trade Secret Information (" Confidential Information ") of Informatica Corporation and may not be copied, distributed, duplicated, or otherwise reproduced in any manner without the prior written consent of Informatica. While every attempt has been made to ensure that the information in this document is accurate and complete, some typographical errors or technical inaccuracies may exist. Informatica does not accept responsibility for any kind of loss resulting from the use of information contained in this document. The information contained in this document is subject to change without notice. The incorporation of the product attributes discussed in these materials into any release or upgrade of any Informatica software product—as well as the timing of any such release or upgrade—is at the sole discretion of Informatica.


Ternstroemia guineensis is described from a sandstone table mountain at Kounounkan, possibly the last in the Fouta Djallon (Guinea Highlands) to remain largely unimpacted by humans and to have mainly intact natural habitats. It occurs about 2400 km westward of the nearest existing record (Nigeria) of the genus in Africa. It is confined to cloud (submontane) forest in galleries along watercourses. Its conservation status is assessed as Endangered using the IUCN 2012 criteria. The species differs from the other two African highland species, T. cameroonensis and T. polypetala, in having hermaphrodite flowers with a long subcylindric style and punctiform stigmas, and petals connate at the base into a tube (not dioecious, with a short style and cone-like stigmas, and free petals) resembling in these features the neotropical Ternstroemia species, as does also the lowland wetland T. africana of Nigeria, Gabon and Angola. Citation: Cheek M., Haba P. M., Konomou G. & Burgt X. M. van der 2019: Ternstroemia guineensis (Ternstroemiaceae), a new endangered cloudforest shrub with neotropical affinities from Kounounkan, Guinea, W Africa. – Willdenowia 49: 351–360. doi: https://doi.org/10.3372/wi.49.49306 Version of record first published online on 26 November 2019 ahead of inclusion in December 2019 issue.


Summary form only given. The control of CEP-slip of mode-locked laser oscillators has been demonstrated recently. To use the amplified high-intensity pulses, however, measurement of the CEP on a single-shot basis is preferable. Here, we propose a method for the single-shot measurement of the CEP by observing the electron angular distribution generated by ionization by a time-dependent polarization (TDP) pulse. Some important points such as the broadening of the distribution, Gouy phase shift, phase difference between the two components, and the asymmetric pulse shape, are discussed. This method is robust against intensity fluctuation because the positions of the peaks depend only on the CEP and the relative heights of the peaks depend on the peak intensity.


Mainly to the Changzhou extant Ming and Qing Dynasties stone bridge ingredient,the structure,the model and the carving and so on,this article has carried on the discussion which explains the profundity in simple language.The hope is through protects these limited historical heritage,to bring more values for the developments of Changzhou's urban construction and traveling,ecology and so on.


In the article the issue of psychological readiness for marriage is raised. On the basis of the theoretical analysis a multi-component model of psychological readiness for marriage is developed and proved. The author's concept is introduced where psychological readiness for marriage is personal formation the basic system components of which are value orientations, marriage motivation, ideas of marital hierarchy, marital attitudes and expectations, ideas of marital relations. For empirical evidence of the hypothesis made by us the postulation has been taken that any system has a number of attributes, and one of them is an interrelation of separate elements of the system. By means of the methods of mathematical statistics correlation matrices have been obtained which contained multiple significant both positive, and negative relations between the parameters included into the research. The analysis and interpretation of the data obtained in the research is provided. DOI: 10.5901/mjss.2015.v6n6s1p452


The burden of chronic mental illness on family caregivers is considerable. Family contact with mental health professionals can relieve this burden by improving the caregiver's knowledge about mental illness and alleviating their sense of isolation.

This Cleveland study surveyed family contacts with mental health professionals and their satisfaction with this contact in 117 white …


We compute the light antiquark flavor asymmetry in the proton using the Chiral Quark Model ($\chi_{\rm QM}$). The distribution functions for the light antiquarks $\bar{d}(x)$ and $\bar{u}(x)$ have been extracted with the help of experimental data from NuSea/E866 and HERMES for the Bjorken$-x$ range $0.015<x<0.35$ as well from the most recent SeaQuest data for an extended $x$ range $0.13<x<0.45$. Our results on the $\bar{d}(x)-\bar{u}(x)$, $\frac{\bar{d}(x)}{\bar{u}(x)}$ and Gottfried Integral $I_G$ are in agreement with the experimental data and confirm the presence of enhanced $\bar{d}$ sea whose origin is purely non-perturbative based on chiral symmetry breaking in QCD.


The Wiener index (W ) is a structural descriptor of organic molecules. It is defined as the sum of distances between all vertices of a molecular graph. Some properties based on the decomposition of the Wiener index fo r catacondensed benzenoid graphs are presented. In particular, it is shown that W(G ) = W ( H ) if and only if W22 (G) = W22 ( H ) , where W22 (G) denotes the sum of distances between vertices of degree 2 in a benzeno id graph G .


Padala Olga, Krupa Adrianna, Putowski Maciej, Konopelko Michal, Piasek Ewa. The efficacy of art therapy in psychiatric patients. Journal of Education, Health and Sport. 2019;9(8):377-383. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3376782 http://ojs.ukw.edu.pl/index.php/johs/article/view/7324 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.08.2019. Revised: 15.08.2019. Accepted: 23.08.2019. The efficacy of art therapy in psychiatric patients Padala Olga, email@example.com ORCID:0000-0003-1469-0877 1st Department of Psychiatry, Psychotherapy and Early Intervention Medical University of Lublin, Gluska Street 1, 20-439 Lublin, Poland Krupa Adrianna, firstname.lastname@example.com ORCID:0000-0003-0866-3952 Department of Human Anatomy, Medical University of Lublin, Jaczewskiego 4 Street, 20-090 Lublin, Poland Putowski Maciej, firstname.lastname@example.com ORCID:0000-0002-7575-2456 Department of Experimental Hematooncology, Medical University of Lublin, Chodźki 1 Street, 20-093 Lublin, Poland Konopelko Michal, email@example.com ORCID:0000-0003-4103-7400 Department of Otolaryngology and Laryngological Oncology, Medical University of Lublin, Jaczewskiego 8, 20 954, Lublin, Poland Piasek Ewa, email@example.com, ORCID:0000-0003-3344-4022 I Clinic of Anaesthesiology and Intensive Therapy, Medical University of Lublin, Jaczewskiego 8, 20 954, Lublin, Poland Abstract: Introduction: Art therapy is a form of psychotherapy that uses art media as its primary mode of expression and communication and enables individuals to use art to creatively express themselves. Art therapy is used to improve cognitive and sensorimotor functions, foster self-esteem and self-awareness, cultivate emotional resilience, promote insight, enhance social skills, reduce and resolve conflicts and distress. Purpose: The purpose of the review is to present the different uses of art therapy in psychiatric patients. State of knowledge: National Institute for Health and Clinical Excellence identifies that arts therapies, including art therapy or art psychotherapy, dance movement therapy, body psychotherapy, drama therapy and music therapy, are considered to improve negative symptoms of psychosis. Improved social skills are likely to be associated with increases in prosocial behaviours. Art therapy interventions are effective in reducing trauma symptom severity and anxiety in traumatized adults. Art and music therapy programs were effective in reducing the degree of depression. Summary: Art therapy is a part of therapy in many psychiatric diseases, including depressive disorders, post-traumatic stress disorder and psychotic disorders. Although the effectiveness of art therapy has been confirmed by some studies, this topic should still be investigated so that art therapy can become more effective and available for bigger group of patients. Key words: art therapy, PTSD, depression, psychotic disorder, schizophrenia


Artificial Neural Networks (ANN) were trained by using an extensive radiolarian census dataset from the Nordic (Greenland, Norwegian, and Iceland) Seas. The regressions between observed and predicted Summer Sea Temperature (SST) indicate that lower error margins and better correlation coefficients are obtained for 100 m (SST100) compared to 10 m (SST10) water depth, and by using a subset of species instead of all species. The trained ANNs were subsequently applied to radiolarian data from two Norwegian Sea cores, HM 79-4 and MD95-2011, for reconstructions of SSTs through the last 15,000 years. The reconstructed SST is quite high during the Bølling–Allerød, when it reaches values only found later during the warmest phase of the Holocene. The climatic transitions in and out of the Younger Dryas are very rapid and involve a change in SST100 of 6.2 and 6.8 8C, taking place over 440 and 140 years, respectively. SST100 remains at a maximum during the early Holocene, and this Radiolarian Holocene Optimum Temperature Interval (RHOTI) predates the commonly recognized middle Holocene Climatic Optimum (HCO). During the 8.2 ka event, SST100 decreases by ca. 3 8C, and this episode marks the establishment of a cooling trend, roughly spanning the middle Holocene (until ca. 4.2 ka). Successively, since then and through the late Holocene, SST100 follows instead a statistically significant warming trend. The general patterns of the reconstructed SSTs agree quite well with previously obtained results based on application of Imbrie and Kipp Transfer Functions (IKTF) to the same two cores for SST0. A statistically significant cyclic component of our SST record (period of 278 years) has been recognized. This is close to the de Vries or Suess cycle, linked to solar variability, and documented in a variety of other high-resolution Holocene records. D 2005 Elsevier B.V. All rights reserved.


OBJECTIVES
This study was designed: 1) to evaluate the effect of weight loss on body fat distribution, 2) to determine whether indices of body fat distribution can be considered as a prognostic indicator for the ability to lose weight and 3) to evaluate whether a change of body fat distribution is associated with changes in plasma glucose, lipids and lipoproteins in both sexes in order to evaluate a gender difference.

METHODS
63 obese subjects (41 women and 22 men) were treated on an outpatient basis with an energy-reduced, protein-enriched low calorie diet (3150-4200 kJ/day) for a 6-month period. They were divided in different groups according to gender and body fat distribution using the waist-to-hip circumference ratio.

RESULTS
Body fat topography can be altered by dieting, but not by more than it increases when a person gains weight. Body fat distribution seems to be a significant prognostic indicator for the ability to lose weight in women but not in men. Although body weight and the waist-to-hip circumference decreased significantly, no relationships were found between percent decrease in these parameters and percent changes in plasma glucose, lipids and lipoproteins.

CONCLUSION
We conclude that an important caloric deficit may lead to a series of metabolic improvements but that gender and the type of fat distribution are important confounding factors in the prediction of metabolic success.


Based on the characteristics of local agricultural tourism region of the project planning mode,the planning and development goals are analyzed and summarized for the implementation of Taiwan peasants innovation park in Gucheng town,Caochun county,Nanjing,the feasibility of the argument has been done for the scenic spots,related infrastructure and the overall construction of the landscapes,also it puts forward reasonable understanding and suggestions by concluding the above three.It provides the conceptual model which can be easily used for the Nanjing region of agriculture sightseeing theme parks and characteristic agriculture sightseeing tourism construction.


The thermal and fluid dynamic disturbances caused by the insertion of a Langmuir probe into a flowing thermal plasma are examined. Attention is paid to a 5-mm-long, free burning 200-A argon plasma at atmospheric pressure. It has been found that the disturbances caused by the probe are so severe that probe measurements cannot refer directly to an undisturbed plasma. The difficulties in interpreting the probe voltage-current (V-I) characteristics are discussed. The use of a Langmuir probe as a general diagnostic tool for the plasma conditions investigated is not yet a practical proposition.


Since the Second World War, economic planning by a central authority has become increasingly popular in developing countries. The governments of the newly independent nations of Southeast Asia believe that to achieve a rapid economic growth, each country must operate on a planned basis. Economic planning was accepted as an essential means for guiding and accelerating economic development. -- Scope of the Thesis -- This thesis attempts a general survey of economic planning in eight countries namely: Burma, Thailand, Malaysia, Indonesia, Laos, Cambodia, Vietnam and the Philippines. The basic problems faced in the process of economic planning as well as effectiveness of the plans in Southeast Asian regions are considered. As countries in Southeast Asia have similar economic, social and cultural characteristics, certain generalizations can be made with regard to their basic development problems. -- Economic planning implies a substantial degree of centralization in policy-making particularly if the aim, in part, of such planning is improving the climate for private enterprise and perfecting the operations of relatively free markets. In Southeast Asia, although a certain amount of government planning exists in all the countries, the content of their plans varies considerably. Intensive study of the plans of each individual country is beyond the scope of the thesis; therefore, only basic aspects of economic planning are considered on a regional basis. However, as Burma was the first country in Southeast Asia which attempted comprehensive planning on the aggregate as well as the sector level, the experience of economic planning in Burma is discussed in some detail. -- The research covers the period from the end of the Second World War until 1960. Thereafter, the role of economic planning in Southeast Asia has increased in importance. However, as great variations now exist in the approaches, formulation and execution of plans, it is not appropriate to make generalizations on the basis of the experience in planning of Southeast Asia as a whole after 1960. -- Objective of the Thesis -- The main objective is to analyse the reasons the countries in Southeast Asia relied heavily on central planning for their economic development and how successful they have been in their attempts to achieve rapid economic planning. In other words, this thesis is to analyse: -- 1. The basic problems facing the Southeast Asian countries. -- 2. Why the governments attempted to solve the problems through economic planning. -- 3. The experience of Burma in her attempts to achieve rapid growth through a comprehensive economic planning. -- 4. The effectiveness of economic planning in the region as a whole. -- 5. The reasons why national plans have failed to achieve their objectives. -- 6. Possible solutions for some of the problems these nations have faced in planning. -- The writer has obtained most of the necessary materials from United Nations publications, especially those of the Economic Commission for Asia and the Far East. Research on the experience of economic planning in Burma was based mainly on the data provided by the Central Statistics and Economics Department, Ministry of National Planning, and annual government publications such as Economic Survey of Burma. Detailed analysis of the experience of other Southeast Asian countries could not be undertaken due to the limited amount of information available.


First step is to prepare aluminum colloid with NaAlO2 and Al2(SO4)3 as raw materials.Second step is to neutralize soluble nickel salt and rare earth nitrate with alkaline precipitator.Then the mixture will be added into the above mentioned aluminum colloid.Finally,the catalyst is formed after washing,drying,and reducing.Catalyst has the highest activity while the alumina carrier′s surface area is(300±10) m2/g;comprehensively considering the influence of temperature on alumina carrier′s surface area and catalyst′s filtration performance,85 ℃ is selected as the optimum temperature;and catalyst′s activity is the best while the volume ratio of nitrogen gas to hydrogen gas in reducing gases is 3∶1.Evaluation of catalytic activity results showed that the performance has reached the level of imported products.


AmpC beta-lactamase producing organisms are traditionally treated with carbapenem or fluoroquinolone antibiotics. Recent studies, however, describe similar clinical outcomes in patients that receive cefepime or piperacillin/tazobactam. We sought to assess outcomes in patients with bloodstream infections caused by AmpC-producing organisms that received beta-lactams compared non-beta-lactam therapy.

 Data was obtained retrospectively from the electronic health record (EHR) from January 2012 to February 2020. The primary objective was 30-day mortality from the day of first positive blood cultures with Enterobacter spp., Citrobacter spp., or Serratia spp. in patients who received non-beta-lactam therapy (carbapenem, fluoroquinolone, trimethoprim/sulfamethoxazole) to those who received beta-lactam therapy (cefepime, piperacillin/tazobactam). Secondary objectives included 30-day recurrence of bacteremia, pathogen isolated, source of bacteremia, hospital length of stay, and duration of antimicrobial therapy.

 A total of 90 patients were included, 50 in the non-beta lactam group and 40 in the beta-lactam group. Demographics were similar between groups. Thirty-day mortality was significantly higher in the beta-lactam group (20% vs 2%, p=0.009). Enterobacter spp. was the most frequently identified pathogen (67%), most commonly isolated from a urinary (31%) or intra-abdominal source (22%). The average duration of antibiotic therapy was significantly higher in the non-beta lactam group (18 vs 12 days, p=0.001). In contrast, there was no significant difference found in hospital length of stay, recurrence of bacteremia, pathogen isolated or source of bacteremia between groups.

 Beta-lactam therapy for the treatment of bloodstream infections caused by Amp-C producing organisms was associated with significantly greater 30-day mortality compared to patients that received non-beta-lactam therapy.

 All Authors: No reported disclosures


Background: Carbohydrate content estimation is one of the techniques in diet management that can provide flexibility in choosing food and can help adolescents with type 1 diabetes mellitus (T1DM) to identify blood glucose patterns. Dietary regulation, especially monitoring of carbohydrate intake, is the main determinant of post-meal blood glucose in T1DM. Aim: The aim of this study was to assess the effect of carbohydrate content estimation among adolescents with type 1 diabetes on their glycemic control. Research Question: What is the relation between carbohydrate content estimation among adolescents with type 1 diabetes and their glycemic control?. Setting: The study was conducted in the outpatient Children's Diabetes Clinic, Children's Hospital, Ain Shams University. Subjects: A sample of 81 adolescents with type 1 diabetes between 12-18 years of age. Data collection tools: 1) Diabetic adolescent assessment sheet (by interview) included the studied adolescents' characteristics, diabetes history and physiological assessment, 2) Ped Carb Quiz (PCQ) to assess the studied adolescents' carbohydrate recognition and insulin dosing accordingly . Results: The results of this study revealed that less than two thirds had been previously hospitalized due to DKA, half of them had HbA1c 8 - <10 % with mean HbA1c 9.7 ± 2.343% and total PCQ score meanX̄±SD was 32.03±10.34. Conclusion: It could be concluded that adolescents with type 1 diabetes had a low level of recognition of carbohydrate content estimation and there was a non-significant correlation between glycemic control and their


Objective
To analyze the value of color Doppler ultrasonography in the differential diagnosis of benign and malignant space occupying lesions of breast.

Methods
Sixty-five patients with breast space occupying lesions were selected as the research objects, and were checked by color Doppler ultrasound and conventional ultrasound examination. Property of leison, benign or malignant, was determined by to the examination results. At the same time, the pathological diagnosis was carried out on all subjects, and the results of the two examinations were evaluated with the pathological diagnosis as the gold standard. The sensitivity, specificity and accuracy of the two diagnostic methods were compared.

Results
In 65 patients, 85 lesions were checked out by pathological diagnosis with 35 cases (41.18%) of benign breast lesions, 50 cases (58.82%) of malignant breast lesions; the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of color Doppler ultrasound in the diagnosis of benign and malignant female occupying lesions were 97.14% (34/35), 96.00% (48/50), 96.47% (82/85), 94.44% (34/36), 97.96% (48/49), which were significantly higher than those of conventional ultrasound[74.29% (26/35), 78.00% (39/50), 76.47% (65/85), 70.27% (26/37), 81.25% (39/48)], the difference was statistically significant (P<0.05).

Conclusions
Color Doppler ultrasound has advantages of high sensitivity, specificity and accuracy in the differential diagnosis of benign and malignant breast lesions in middle-aged and elderly women, and it is worthy of popularization.

Key words:
Conventional ultrasound; Color Doppler ultrasonography; Breast cancer; Space occupying lesion


Restoring historic lake-fringe wetlands is considered a favorable means of reducing lake phosphorus levels; however, it is unclear how various strategies for managing wetland connectivity influence phosphorus release. We investigated the relationships between temperature and soil characteristics of restored wetlands to identify management strategies that minimize external phosphorus loading to Upper Klamath and Agency Lakes. We flooded soil cores at various temperatures and analyzed them for several forms of phosphorus and other physical properties. We compared measures of microbial activity and physical characteristics of phosphorus fractions within the wetland soils to forms of phosphorus in water relevant to phosphorus-loading in the lakes. Greater release rates of total phosphorus occurred in summer temperature treatments for all study wetlands (average 31.81 to 240.61 mg/m2/d), while release rates of soluble reactive phosphorus (average −15.9 to 62.19 mg/m2/d) varied with temperature and soil characteristics. Wetlands with mineral soils and direct hydrologic connectivity to the lakes released the lowest concentrations of total phosphorus, while soluble reactive phosphorus release varied across management strategies and soil types. These differences can be explained by the dominant phosphorus processes associated with the hydrology and biogeochemistry of the individual sites, and temperature and potential for microbial activity at the timing of inundation. Our results provide evidence that directly connected wetlands may release less phosphorus than indirectly or mechanically connected wetlands, due to early timing of inundation and longer duration of inundation.


Model combination is an important approach to improving the generalization performance of Support Vector Machine(SVM), but usually has low computational efficiency. An effective SVM model combination method based on Bayesian model averaging over regularization path is presented. The initial candidate model set is constructed using regularization path algorithm, and the probabilistic interpretation of Support Vector Machine is described. The SVM prior is simply a Gaussian Process(GP)over the models, while model posterior probability is obtained by Bayesian formula, and the combination on the initial models is achieved using Bayesian model averaging. Comparative experiments on benchmark databases against common cross-validation model selection methods and Wahba's Generalized Approximate Cross-Validation(GACV)show that the proposed combination algorithm is effective and efficient.


The invention discloses an underground omnibearing data acquisition system, which comprises a mass data storage module, a data integration collection module and data acquisition and storage modules convenient to carry, wherein the data acquisition and storage module comprises a data acquisition and processing part and a solid-state data storage part; the solid-state data storage part stores data acquired and processed by the data acquisition and processing part; the mass data storage module is in communication connection with the data collection module; the data collection module is in communication connection with each data acquisition and storage module, and performs node numbering and Internet protocol (IP) address mapping on the data acquisition and storage modules. The system overcomes the shortcomings of fixed point data acquisition in the prior art, processes and plays the acquired data in real time, and moreover, ensures that the data may not be lost for long and can be reserved after an accident in the most severe environment to greatly help to make safety responsibilities clear.


The dental health education approach is the way to communicate with the target when providing information. There are various choices of dental health education methods such as lectures, discussions, interviews, and storytelling. Based on the results of interviews with 10 students at Pakis VIII Surabaya Elementary School, their knowledge of oral health maintenance was included in the very low category, with the number of correct answers <40%. The problem in this study is the low level of knowledge about dental hygiene of students at SDN Pakis VIII Surabaya. The purpose of this study is to determine the effectiveness of the storytelling method towards knowledge level of dental and oral hygiene maintenance of grade 4A students at SDN Pakis VIII Surabaya. This type of research is a Quasi Experiment with one group pretest-posttest design. Respondents in this study were all students of grade 4A at SDN Pakis VIII Surabaya, amounting to 37 students with 15 female students and 22 male students. The data collection method used a questionnaire. Data analysis techniques used the Wilcoxon Signed Rank test. The results of this study are an increase of knowledge in grade 4A students at SDN Pakis VIII Surabaya after being given dental health education using storytelling methods. It can be concluded that storytelling method is effective in increasing the knowledge level about dental and oral hygiene maintenance in grade 4A students of SDN Pakis VIII Surabaya.


Agnoprotein is an important regulatory protein of the human polyoma JC virus (JCV) and plays critical roles during the viral replication cycle. It forms highly stable dimers and oligomers through its Leu/Ile/Phe‐rich domain, which is important for the stability and function of the protein. We recently resolved the partial 3D structure of this protein by NMR using a synthetic peptide encompassing amino acids Thr17 to Gln52, where the Leu/Ile/Phe‐ rich region was found to adopt a major alpha‐helix conformation spanning amino acids 23–39. Here, we report the resolution of the 3D structure of full‐length JCV agnoprotein by NMR, which not only confirmed the existence of the previously reported major α‐helix domain at the same position but also revealed the presence of an additional minor α‐helix region spanning amino acid residues Leu6 to lys13. The remaining regions of the protein adopt an intrinsically unstructured conformation. J. Cell. Biochem. 118: 3268–3280, 2017. © 2017 Wiley Periodicals, Inc.


The determination of various resource affinities of processes is an important parameter for making effective scheduling decisions by the schedulers in any operating systems kernel. The resource affinities of a set of processes may be dynamic in nature based on application logic and execution environments. This paper proposes a novel probabilistic estimation model and corresponding classifier algorithm to segregate processes in different queues based on respective resource affinities. The classifier algorithm is online in nature and tracks the dynamic variations of resource affinity patterns of processes. The algorithm classifies processes according to resource affinities for scheduling purposes. The effects of dilated estimation periods are investigated. Experimental results indicate that the estimation model and algorithm successfully classifies a set of processes based on execution traces.


The morphological and rheological behaviors of toughened epoxy resins modified with core-shell rubber particles (CSR) were studied. These rubber particles were based on a poly (butadiene-co-styrene) core and a crosslinked poly (methyl methacrylate) shell. The effect of functionalized groups was performed on two types of CSR particles: first, those containing carboxyl-functionalized groups (CSf), and second, particles containing no carboxyl-functionalized groups (CSnf) in the PMMA-shell. For these blends, the correlations between the morphology, particle dispersion state and their rheological behaviors before curing were investigated. Preliminary work using TEM micrographs indicated that the blends modified with CSf and CSnf exhibited the same particle size but differed with respect to the dispersion state. Rheological behavior of these blends was assessed in steady shear flow and dynamic viscoelastic experiments. Yield viscosity near-zero shear rate occurred in the DGEBA/ CSf blend presenting non-Newtonian behavior at the particle volume fraction of 20% vol. The rheological behavior was clearly related to the state of particle dispersion and analyzed taking into account interactions between the particles-particles and the particles-matrix. The Williams-Landel-Ferry (WLF) shift procedure was used to construct modulus master curves G' and G from the elastic solid state to molten polymers. A secondary plateau existed at low frequencies and was related to the presence of interactions leading to a physical network-type structure. The deviation between theoretical G' (Palierne's model) and experimental G' values was evaluated and exhibited high elasticity at the terminal zone, which correlated well with available literature.


In contrast to models of compassion within existing organizations, this grounded theory study examines how ventures emerge relying on localness and community in direct response to 'opportunities' to alleviate suffering in the aftermath of a natural disaster. While a natural disaster is a surprising disruptive event devastating a local community, that local community is nested within a broader community, which can be a source of abundant resources. Ventures created in the aftermath of a natural disaster, given local knowledge and unencumbered by pre-existing systems, procedures, and capabilities, are highly effective at connecting the broader community with the local community through customizing resources to meet victims' needs and to quickly delivering these resources to alleviate suffering.


Background Studies comparing venous total carbon dioxide (tCO2) and standard hydrogen carbonate (HCO3–(P,st)) has shown diverse results, and it is debatable whether these two parameters can be used interchangeably for workup of acid–base disorders in a hospital setting. Method All patients with an HCO3–(P,st) requisition from any department at Odense University Hospital between 11th May 2021 and 1st June 2021 had tCO2 and HCO3–(P,st) analysed simultaneously. TCO2 was measured on Cobas® 8000, c702 module, while HCO3–(P,st) was calculated based on measurements on ABL835 Flex. Results From 1210 patients, mean (standard deviation (SD)) was 22.9 (3.7) mmol/L for tCO2 and 22.5 (2.9) mmol/L for HCO3–(P,st). TCO2 range was 10.1–42.3 mmol/L and 11.7–41.4 mmol/L for HCO3–(P,st). Linear regression showed that tCO2 (mmol/L) = −2.90 + 1.15 × HCO3–(P,st) (mmol/L) with R2 = 0.81. Bias (mean (SD) difference) between tCO2 and HCO3–(P,st)) was 0.4 (1.7) mmol/L with a −5.0–9.6 mmol/L range. Limits of agreement was −2.90–3.70 mmol/L. Comparison of classification within, above or below reference interval for tCO2 and HCO3–(P,st) showed that 984 samples (81%) retained their classification. Only one sample (0.1%) would be severely misclassified (outside the respective reference intervals) if HCO3–(P,st) was considered the gold standard. Of the samples investigated, 46.1% had a mean difference between tCO2 and HCO3–(P,st) of 0–1 mmol/L and 30.3% had 1.1–2.0 mmol/L. Conclusions Our results indicate that venous tCO2 and venous HCO3–(P,st) can be used interchangeably in a hospital setting for workup of acid–base disorders.


The study aims at determining the impact of electronic commerce on national economic growth in Saudi Arabia during the period (2001-2013). The study uses an econometric model to get empirical research between E-commerce development and economic growth using the latest data of Saudi E-commerce development. The regression estimation shows that capital-labor ratio, the size of the private sector, Terms of Trade, number of business transactions via internet, information and communication technology expenditure, and the number of credit cards (as a method of payment) have significant and positive impact on economic growth, while the size of public sector has significant and negative impact on economic growth. The study recommends that Saudi government, enterprises and consumers need to pay more attrition to E-commerce to increase investment in infrastructure, pushing more internet users to develop online shopping habits so as to improve the overall development level of the E-commerce; thus promoting the effective national economic growth.


Textual similarity deals with determining how similar two pieces of texts are, considering the lexical (surface forms) or semantic (meaning) closeness. In this paper we applied word embeddings for measuring e-commerce product title similarity in Brazilian Portuguese. We generated some domainspecific word embeddings (using Word2Vec, FastText and GloVe) and compared them with general-domain models (word embeddings and BERT models). We concluded that the cosine similarity calculated using the domain-specific word embeddings was a good approach to distinguish between similar and nonsimilar products, but the multilingual BERT pre-trained model proved to be the best one.


A critical appraisal of the literature on the effects of progressive resisted muscle strengthening as a management strategy for children and adolescents with cerebral palsy (CP) was initiated as a group consensus project by 1 7 clinical physical therapists. Seven articles were reviewed and graded using Sackett's framework. All studies reported an improvement in the performance of individual muscles or groups of muscles after a program of resisted exercise, regardless of the type of exercise or muscle group targeted. Three studies that evaluated muscle spasticity of the antagonistic muscle groups found no deleterious effects. Only one study was classified as level 1 evidence; the remaining six studies were level 5. Caution must be used in interpreting their results because of the limitations in design rigor. The group concluded that progressive resisted exercise of isolated muscle groups increased muscle performance in clients with CP, but the relationship between strength training and functional abilities remains unclear.


. Analysis of ionized gas velocity fields in the circumnuclear regions of 13 normal spiral galaxies has shown that about half of them reveal a discrepancy between the kinematical axis at R < 2" and the pho tometric or kinematical axes of the outer regions. This result indicates a high frequency of occurrence of non-axisymmetric gravitational poten tials in the inner few hundred parsecs of galaxies. The possible nature of these minibars is discussed.


This paper aimed to analyze the association of polymorphism of GSTM1 0/0 genotype with laryngeal cancer along a hospital based case‐control study. Polymorphisms of GSTM1 0/0 of samples from 36 patients with laryngeal cancer and 35 healthy controls were detected by PCR method. The reaction used as GSTM1 primers, using the sequence sense: 5′‐CTGCCCTACTTGGATTGATGGG‐3′ and antisense: 5′‐TGGATTGTAGCAGATCATGC‐3′. N Acetyl transferase 1 (NAT1) gene using the primers sense: 5′‐TAAAAGTAAAATGATTTGCTTTCG‐3′ and antisense: 5′‐GCTTTCTAGCATAAATCACCAA‐3′ was used as internal positive control. Two sided 2 and multivariation analysis were used to analyse the results. The proportions of GSTM1 deleted genotype in cases and controls were 47.2% and 54.3%, respectively. There was significant increment of GSTM 0/0 genotype frequency in moderate smokers group of patients compared to control (P=0.033, OR= 4.78, 95% CI=1.30‐7.13). We conclude that GSTM1 deleted genotype may be a genetic susceptibility marker for laryngeal cancer whose exposed to low doses carcinogens. The absence of this enzyme seems to have a role in the development of laryngeal cancer, in which the mechanism still needs further investigation.


In order to predict the changing trends of the reservoir water quality,based on the real-measuring data of water quality and the principle of helix cellular automata to organize the sampled data,a BP neural network prediction model was proposed,and an open and flexible prediction system based on virtual instrument was developed.This system was developed by using LabVIEW and C++,the test results show that the model is accurate,simple to use,and it is strongly feasible and practical,it can be adapted for different users and environments.


Polypyrrole particles (Ppy) were chemically synthesized by H 2 O 2 and K 2 Cr 2 O 7 induced polymerization. We discuss the dependence of several oxidizing agents on the synthesis of polypyrrole particles and covalent immobilization of proteins. During modification of Ppy particles by secondary horseradish peroxidase (HRP) labeled antibodies we observed that additional oxidation of Ppy particles with K 2 Cr 2 O 7 increased the efficiency of protein immobilization 1.4 and 3.8 times for H 2 O 2 and K 2 Cr 2 O 7 initiated particles, respectively. The possibility to apply Ppy particles modified by the bovine leukemia virus (BLV) protein gp51 to detect specific antibodies in the blood serum of BLV-infected animals was investigated and is presented in this paper.


Tourism is the largest sector of the economy in the Maldives, as it plays an important role in earning foreign exchange revenues and generating employment in the tertiary sector of the country. The archipelago of the Maldives is the main source of attraction to many tourists visiting the country. Tourism began in the Maldives in the late 1900's. A United Nations mission on development which visited the Maldives Islands in the 1960s did not recommend tourism, claiming that the islands were not suitable. Ever since the launch of the first resort in Maldives in 1972, however, tourism in Maldives has flourished. Tourism in Maldives started with just two resorts. At present, there are over 80 resorts located in the different atolls constituting the Republic of Maldives. Over the past few decades, the number of tourists in Maldives has risen continuously. Today, more than 500,000 tourists visit the Maldives each year. This paper gives a detailed account of the development of tourism industry and the initiatives taken by the Maldivian government to promote tourism in the country.


Marandi, L. T. and L. Rashidpour, 2017. Impacts of credits on agricultural mechanization and development in Urmia County. Bulg. J. Agric. Sci., 23 (6): 922–928 The purpose of this study is to investigate the impact of Agricultural Bank credit on mechanization promotion in the agricultural sector in Urmia County, West Azerbaijan province of Iran. This is a cross-survey research and it is applicable in purpose. The statistical community of this study includes farmers working on agricultural farms of Urmia County. Agricultural Bank has provided facilities for 416 people for agricultural purposes. The volume of sample, by referring to the Cochran-Formula which is used as criteria, 200 people were chosen. In this study, a random sampling method was used. For assembling data, a 30-item questionnaire was developed by the researcher based on a set of Likert's 5-choice, which at the end Cronbach's alpha coeffi cient was 0.872. In analyzing the data, descriptive and inferential statistical methods and variable t-test were used to test hypotheses. The results of this study show that the Agricultural Bank's credits have a positive impact on all aspects of agricultural mechanization such as structural modernization of irrigation, decreasing cost, and improving a quality of land, tools and rural economy. Our results are useful for the policy makers and other stakeholders to consider facilities role on agricultural mechanization and development.


A welding deformation control method of a Tokamak vacuum vessel is provided to prevent the determined assembling angles from changing by measuring and confirming welding deformation in real-time and reflecting welding conditions during a succeeding welding operation when welding and thus assembling the sectors to determined assembling angles at the installation position after dividing a vacuum vessel into sectors one and two and transporting the sectors to an installation position. In a welding deformation control method of a Tokamak vacuum vessel, in which the sectors are assembled to determined assembling angles at the installation position after dividing a vacuum vessel into sectors one and two and transporting the sectors to an installation position, the welding deformation control method comprises: a welding pre-treatment and preparation step(S10) of fixing the sectors one and two while reversely deforming the sectors one and two before welding as much as a deformation amount to be generated on the sectors one and two after welding of the sectors one and two, and preparing to observe deformation of the sectors one and two during welding; a welding condition changing step(S20) of feedbacking the observed deformation after welding respective portions to be welded to change welding conditions; a structure welding step(S30) of welding the portions to be welded of the sectors one and two; a welding deformation measuring and welding amount calculating and feedbacking step(S40) of measuring welding deformation generated after welding one portion to be welded to predict welding deformation that can be generated in a succeeding portion to be welded, and checking the welding amount, thereby calculating an estimated welding amount by the final welding to feedback the calculated estimated welding amount; and a welding finishing step(S50) of performing a final dimension inspection and finishing welding of the vacuum vessel at the same time.


Aluminum alloys are lightweight and ductile, and thus widely formed in single point incremental forming (SPIF) technology. Comparing to aluminum alloys, stainless steel sheets are more difficult to deform because pillow defect or bulging defect can easily occur during SPIF process. Pillow defect generated at the sheet center during SPIF process is a major forming limitation that affects the part's formabi lity and increases the forming load. This study aims to systematically investigate the influences of bend severity, tool shape, forming wall angle, and stepdown size on the formation of pillow defect of stainless-steel sheets in SPIF via experiments. Bend severity is the ratio of sheet thickness to forming tool diameter. A series of forming SPIF experiments are carried out on both stainless steels, including grades SS304 and SS316L, to form parts with varying forming wall angles. Forming tools with different shapes are utilized, including hemispherical and flat end tools. The control solution of pillow defect of stainless-steel sheets is analyzed and explored by physical results. Hence, our study advances the in-depth understanding of formation of pillow defect of stainless-steel sheets and further drives the development of single point incremental forming technology.


The antioxidative activity of tea polysaccharide was determined by the capacity of scavenging 1,1-diphenyl-2-picrylhydrazyl(DPPH)free radical, and the evaluated unit was expressed as the equivalent concentration of ascorbic acid. Afterextraction, the antioxidative activities of tea polysaccharides from various teas and different extraction processes were determined.The results showed that there are remarkable effects of region, breed and extraction process on the capacity of scavenging DPPHfreer adical.


The invention relates to plant fiber base polyether glycol and a preparation method thereof, which belong to the field of polymer chemistry. The preparation method is as follows: mixed alcohol, an acid and a non-ionic surfactant are uniformly mixed to obtain a liquefied reagent; dried plant fiber raw materials are added into the liquefied reagent which is heated to the temperature of between 120 and 160 DEG C, and added in batch; after feeding is over each time, the temperature is raised to the temperature before the feeding, and maintained until the mixture reacts for 10 to 20 minutes; the temperature is maintained after the feeding is over, and the mixture reacts for 20 to 120 minutes; solid alkali is added into a reaction system until the pH value is neutral; and the product is obtained after discharging. The plant fiber base polyether glycol prepared by the method can be used for producing hard polyurethane foam with the function of heat insulation.


Objective
To investigate the clinical value of percutaneous minimally invasive techniques on cervical disc herniation.

Methods
One hundred patients with cervical disc herniation from February 2014 to February 2016 were selected and divided into minimally invasive group A and group B according to surgical options. The minimally invasive group A received percutaneous cervical discectomy(PCD) treatment, the minimally invasive group B received percutaneous cervical disc nucleoplasty(PCN) treatment. The clinical outcomes and the stability of the cervical spine between the two groups were retrospectively analyzed before and after treatment.

Results
Postoperative JOA scores of both groups significantly increased compared with before surgery, the differences were significant (P 0.05). The cervical angular displacement, horizomtal displacement variations had no significant difference before and after surgery in either group(P> 0.05).

Conclusions
PCN and PCD in the treatment of cervical disc herniation can effectively promote the signs and symptoms remission, and can effectively avoid the impact on the stability of the cervical spine.

Key words:
Cervical disc herniation; Minimally invasive percutaneous technique; Treatment analysis


An inorganic ion exchanger K/sub 2/(CoFe(CN)/sub 6/) was used for the quantitative analysis of cesium-137 in plant samples. The adsorption coefficient and optimum conditions of analysis were determined. After extraction of the cesium-137 present, the filtrates can be used as model samples. Results show that samples collected in the region of the IRT-2000 reactor at Sofia in recent years are very pure. An increased content of /sup 137/Cs is possessed by samples of the 1963 to 1964 period, as well as from a higher altitude above sea level. A high content of cesium-137 was demonstrated in certain parasitic plants.


Trenching is a form of soil and water conservation engineering that is commonly used and is known to be effective in controlling runoff and increasing water content in the root zone of plants. There are various configurations of trench placement in the field and this study aims to simulate the placement of trench by comparing the three trench configurations to find out which configuration is most effective in capturing surface runoff. The simulation is carried out by calculating the catchment capacity of surface runoff under different rainfall intensity conditions and runoff coefficients in the three trench configurations that have different catchment areas. From the calculation, it is known that configuration 3 in optimal conditions has a comparative advantage of 41.67% - 68.80% (compared to configuration 1) and 27.78% - 52.83% (compared to configuration 2). Meanwhile, configuration 2 has a comparative advantage of 13.89% - 16.06% when compared to configuration 1. From the calculation it is also known that there are conditions where the three configurations will produce a uniform value so that there will be no comparative advantage between the three configurations. This condition is generally above the rain intensity of 50 mm per hour and the runoff coefficient is above 0.45.


It is well known that uniaxial compressive strength of rock increases with loading rate. Loading rate dependency of Young's modulus has been also studied by many authors, however, only a small part are clarified. In this study, testing method are slightly modified to reduce scatter of data. In the testing, Young's modulus at 50% of the peak strength is normalized by that at 10% of the peak strength which is preliminarily obtained under a predetermined loading rate. It was found that this testing method is effective and promising. Seven Japanese rocks were examined. It was found that an andesite, a sandstone and two tuffs exhibited loading rate dependency of Young's modulus. For example, in case of Sanjome andesite, Young's modulus increased 2 % at every ten fold increase of loading rate. On the other hand, Young's moduli of a marble, a granite and a sandstone very slightly decreased with increase of loading rate. With aid of constitutive equations, time dependency of modulus was discussed. It was found that irrecoverable strain delayed to extend when loading rate was high. That is possibly the main reason of increase of Young's modulus with increase of loading rate.


Our results indicate that increasing temperatures will be devastating for the melanic mosquitofish population, resulting in extinction within 1000 years. Despite these findings, our simulations also indicate that if the temperature stabilizes before the melanic mosquitofish becomes extinct the melanic population will also stabilize near the frequencies present at the time the temperature stabilizes. (Supported by Old Dominion University Spring 2013 Undergraduate Research Grant.)


In English teaching,it is very important to cultivate and improve the students'ability to listen.In the article,starting with helping the students to overcome the psychological barriers in listening,offers some scientific and effective training methods in order to improve their ability to listen better.


Spoken word performance lyrically recounting Louise Ashcroft's humorous and emotional experiences as a care worker, accompanied by an arm wrestling contest to find the most alpha member of the audience.


An enormous amount of literature exists on the theory of random noise, the theory and practice of low-noise amplifier design, and measuring techniques involving noise. However, for most engineers and physicists not specializing on noise topics as such, the need is to extract from this mass of know ledge a certain minimum amount of basic theoretical and practical information, suffici ent to enable the normal types of noise problem which arise in the course of elec tronic work to be understood and dealt with in an intelligent manner. The aim in this article is to provide this minimum basic information in, it is hoped, an easy-to-assimilate form, and to quote, for the benefit of those desiring to delve a little more deeply, a few references which have been found particularly worthy of attention.


The detailed analysis of seizure semiology is an essential tool for diagnosing epileptic patients and is particularly important in the evaluation of patients considered for epilepsy surgery. The meticulous clinical observation of epileptic seizures provides information about the localisation and lateralisation of the symptomatogenic zone. Here, we present a video atlas showing a variety of ictal and postictal localising and lateralising phenomena.


This paper presents a fuzzy-goal programming (FGP) approach for Bi-Level Linear Multiple Objective Decision Making (BLL-MODM) problem in a large hierarchical decision making and planning organization. The proposed approach combines the attractive features of both fuzzy set theory and goal programming (GP) for MODM problem. The GP problem has been developed by fixing the weights and aspiration levels for generating pareto-optimal (satisfactory) solution at each level for BLL-MODM problem. The higher level decision maker (HLDM) provides the preferred values of decision vector under his control and bounds of his objective function to direct the lower level decision maker (LLDM) to search for his solution in the right direction. Illustrative numerical example is provided to demonstrate the proposed approach.


Abstract The paper deals with the politics of upgrading urbanized villages in the Pearl River Delta. Urbanized villages are enclaves of formerly autonomous, very densely built-up settlements managed by village committees representing farmers' collectives and inhabited to a substantial extent by migrants and floating workers. In an environment of transition from a labor-oriented regional economy to higher value-added industries and with the ongoing reform processes, local governments try to fully integrate urbanized villages into their respective cities. This comprises an institutional reform, which makes them part of the political and administrative hierarchies and part of a rather physical upgrading strategy intended to overcome urban problems associated with security, health, economic growth and real estate development. However, the customary strategy of comprehensive redevelopment no longer seems feasible. The cities of Guangzhou and Shenzhen are therefore struggling to develop more sophisticated strategies to tackle the challenge of urbanized villages. The focus of this study is on the different approaches developed by the two cities. Whereas Guangzhou tried to establish a piecemeal strategy, taking the somewhat different local conditions into account, Shenzhen tried to proactively promote the diverse strengths and location factors of the urbanized villages and facilitate the integration process by establishing larger regeneration units, thus comprising the areas surrounding urbanized villages. Both cities, however, are gradually adapting their strategies to the respective local conditions. Our study investigates micro-level urban governance and thereby tries to identify how the various stakeholders organize decision-making in a struggle for power between the different administrative levels in formal and informal communicative settings. It seeks the conditions required for influential development strategies when dealing with different degrees of inherited autonomy and compares the levels of power that planning has in the two cities.


1 Eisen DB, Michael DJ. Sebaceous lesions and their associated syndromes: part I. J Am Acad Dermatol 2009; 61: 549–60. 2 Mohamed KB. Facial lesions resembling leprosy. Int J Lepr Mycobact Dis 2001; 69: 35–7. 3 Cohen PR, Kohn SR, Kurzrock R. Association of sebaceous gland tumors and internal malignancy: the Muir-Torre syndrome. Am J Med 1991; 90: 606–13. 4 Mathiak M, R€ utten A, Mangold E et al. Loss of DNA mismatch repair proteins in skin tumors from patients with Muir-Torre syndrome and MSH2 or MLH1 germline mutations: establishment of immunohistochemical analysis as a screening test. Am J Surg Pathol 2002; 26: 338–43. 5 Tagliolatto S, Santos Neto Ode O, Alchorne MM, Enokihara MY. Sebaceous hyperplasia: systemic treatment with isotretinoin. An Bras Dermatol 2015; 90: 211–15.


Environmental sustainability, as well as social and economic well-being, must be considered in every stage of a product lifecycle, from conceptual design to its retirement. Even though this sustainability-centric approach represents a critical driver for innovation, it also increases the design complexity. Nowadays, the maritime transport accounts for a large share of transport demand, and the importance of sustainable ship design is increasingly growing, not only for ethical and legislative but also for competitive reasons. The design of a sustainable ship considering all those aspects is a complex problem in this regard. One way to manage the complexity is to identify and address the functional couplings of the system at the early stage of the ship design. The Axiomatic Design methodology has been used for accommodating such a challenge in engineering systems design, and therefore, this thesis investigates the conceptual design of a merchant ship's conventional propulsion system with a view to the Axiomatic Design framework and known sustainable engineering principles. The Bayesian machine learning technique is proposed as a data-driven method for calculating the probability of achieving specific sustainability-related functional requirements, selecting the best design parameters among the proposed alternatives, and identifying hidden design couplings that the designers could not identify in the conceptual design stage. The case presented in this thesis can provide a scalable source for the total ship design following sustainable engineering principles in two aspects: 1) Axiomatic Design as a methodology to control the complexity of sustainable ship design and 2) Bayesian machine learning technique as a supportive tool for improving system's architecture and assessing system's sustainability impact.


Can a rechargeable battery, linked to an atomiser and cartridge of liquid nicotine, 'massively' reduce the individual and population  risks of traditional cigarette smoking? Or is the increasingly ubiquitous e-cigarette a dubious, poorly-controlled 'aid to quitting', resulting in actual dual use with unacceptably high toxin levels? The jury is out scientifically, with South African role players on either side producing evidence for and against the device.


The catalytic and photocatalytic activity of brookite TiO2 nanorods toward methanol, acetaldehyde, and acetic acid was studied using temperature-programmed desorption (TPD). For thermally activated reactions, the brookite nanorods were found to exhibit catalytic properties similar to those reported previously for the rutile and anatase phases of TiO2. In particular, methanol adsorbed dissociatively on 5-fold coordinate surface Ti cations and underwent dehydrogenation to formaldehyde and deoxygenation to methane near 650 K; acetaldehyde adsorbed on these sites underwent aldol condensation to produce crotonaldehyde and to a lesser extent reductive coupling to butene between 460 and 600 K; acetic acid adsorbed dissociatively to produce acetate species that decomposed to produce ketene at 630 K. The brookite nanorods were also found to be photocatalytically active for the coupling of methanol to methyl formate and the photo-oxidation of acetaldehyde to acetate. Lastly, the photocatalytic activity of the brook...


The present invention comprises the at least one first layer at least one second layer, said first layer contains at least one distribution system with at least one flocculating system and the second layer, by contact with water containing at least one excipient for the at least one anti-infective agent and the anti-infective agent to release the free chlorine, said excipients, the combination of excipients and antiinfectives , so that free chlorine 0.1-100 mg / l per hour is released, characterized in that release at a controlled rate antiinfective in water, to a two-layer molded solid water purification products . Furthermore, the present invention relates to a manufacturing method of such products. .BACKGROUND


. In this paper we discuss the behavior of the curvature lines of a transversal eq¨uiaffine vector field along a surface in 3-space at isolated umbilical points. Mathematics Subject Classification (2010). 53A15, 53A05.