The research this paper focuses on is devoted to the study of companies that lead the world market of congress and exhibition services. The research involved case-study, benchmarking, trend analysis, comparative analysis and other methods. The study revealed the leading companies and their leadership strategies. The global COVID-19 crisis calls for reviewing the work of congress and exhibition companies both at the time of the pandemic and after it. The author of the article considers the cases of the leading companies during the pandemic and their anti-crisis strategies conceived to meet the COVID challenges.


A provided preparation method for wool keratin regenerated cellulose fiber comprises the concrete steps: firstly preparing a viscose-rayon spinning solution, then preparing a wool keratin solution, then mixing the viscose-rayon spinning solution and the wool keratin solution, then adding a crosslinking agent, mixing and performing wet-process spinning, so as to obtain wool keratin regenerated cellulose fiber. The wool keratin regenerated cellulose fiber prepared by employing the method has the protein content of 6% or more, and the production technology is simple in process and high in production efficiency.


In this paper, the governing equations of the outrigger system are formulated through the continuum approach and the whole structure is idealized as a shear-flexural cantilever with rotational spring. The effect of shear deformation and flexural deformation of the structure and outrigger-truss are considered and incorporated in the formulation of the governing equations. A displacement based one-dimensional finite element model is developed to predict lateral drift of outrigger system structures under horizontal loads. Numerical results are obtained and compared with previously available results and the values obtained from the finite element package MIDAS. The proposed method is found to be simple and efficient, provides reasonably accurate results in early design stage of tall building structures.


'Australia must have a taxation system which equips it for the coming decades, not for those that have passed. If we do not achieve this, Australians will not enjoy the standard of living this nation has the potential to deliver' (Ralph et al, 1999). One of the outcomes of the increasingly global nature of the resource industry is countries, especially those in close proximity to each other, are now competing for investment in resource projects. A key factor for investors assessing competing resource projects is the host country's fiscal regime, including income tax, as this can significantly affect a project's profitability and cash flow. The purpose of this paper is to give an overview of the income tax regime and issues currently facing the upstream Australian oil and gas industry (Sarich, 20001 ). In particular, this paper will: examine the Federal Government's Review of Business Taxation and identify how the announcements impact on exploration and production activities; compare the Australian income tax regime on exploration and production to other countries in the region with whom Australia competes for investment and capital; and comment on income tax issues facing Australian resource companies when conducting foreign activities.


A second order polynomial regression of the sunspot motion in a recurrent group shows a smooth displacement of the subphotospheric field source. This displacement is seen in the regular motion of the longer-lived spots of the group. The observations of a recurrent group show a sunspot meridian movement toward the pole, contrary to previous results. The qualitative agreement between observational results and the proposed sub-photospheric solar structure suggest that photospheric circulation may be described by sunspot motion.


Structural change detection problems are often encountered in analytics and econometrics, where the performance of a model can be significantly affected by unforeseen changes in the underlying relationships. Although these problems have a comparatively long history in statistics, the number of studies done in the context of multivariate data under nonparametric settings is still small. In this paper, we propose a consistent method for detecting multiple structural changes in a system of related regressions over a large dimensional variable space. In most applications, practitioners also do not have a priori information on the relevance of different variables, and therefore, both locations of structural changes as well as the corresponding sparse regression coefficients need to be estimated simultaneously. The method combines nonparametric energy distance minimization principle with penalized regression techniques. After showing asymptotic consistency of the model, we compare the proposed approach with competing methods in a simulation study. As an example of a large scale application, we consider structural change point detection in the context of news analytics during the recent financial crisis period.


Public contracting has become an increasingly important form of administrative action, so much that the modern state has been characterized as a 'contracting state.' Yet, while public contracting increasingly takes place in globalized markets, the law governing it has been understood traditionally as a purely domestic matter. Conceptual approaches to understanding how public contracts law is transforming in globalized markets are still largely missing. This is particularly important as rules for public contracting in global markets emerge very differently from the domestic context. There is no uniform law-maker, nor are the modes of law-making, and the instruments used, as formalized as in the domestic context. Instead, rule-making in the global context is characterized by a multiplicity of legal instruments and sources, including international treaties, model contracts, and model contracts, and a multiplicity of actors, including international organizations, industry associations, financiers, and arbitrators. The present paper suggests to capture the transformation public contracting is undergoing in times of globalization by putting the processes, instruments and actors that bring about change into the center of attention. Understanding processes of 'internationalization' or 'transnationalization' of public contracts law is argued to be the most sensible way of understanding how 'transnational law of public contracts' emerges and what pressure it exerts on domestic public contracts law.


SoxR protein of Escherichia coli governs a global response against superoxide‐generating agents (such as paraquat) or nitric oxide, and provides broad antibiotic resistance. A redox signal activates SoxR post‐translationally to trigger transcription of a second regulatory gene, soxS. Activated and non‐activated SoxR bind the soxS promoter with the same high affinity, but only the activated protein stimulates soxS transcription. SoxR acts by an unusual mechanism of positive control: the protein binds the soxS promoter between near‐consensus −10 and −35 elements that are separated by an unusually long 19 bp (versus the optimal 17 bp). We have constructed and analyzed site‐specific deletions that alter the promoter element spacing. Reducing the spacer length to 16‐18 bp dramatically elevated basal expression of soxS in vivo and in vitro, and nearly eliminated additional activation by SoxR in response to paraquat. More strikingly, shortening the spacer converted SoxR from an activator into a repressor regardless of paraquat treatment. Gel mobility‐shift assays show that repression by SoxR of the promoters with 17 and 16 bp spacers is due to interference with binding by RNA polymerase. Thus, activated SoxR remodels the unusual configuration of the wild‐type soxS promoter into a highly active form, probably by compensating for the suboptimal distance between the −10 and the −35 elements.


Finkish dispositions, those dispositions that are lost when their conditions of realization occur, pose deep problems for counterfactual accounts of dispositions. David Lewis has argued that the counterfactual approach can be rescued, offering such an account that purports to handle finkish as well as other dispositions. The paper argues that Lewis's account fails to account for several kinds of dispositions, one of which involves failure to distinguish parallel processes from unitary processes.


Here, a book review of Warfare, Violence and Slavery in Prehistory (2005) is presented. The volume, containing 19 case studies, is considered in the context of the growing body of work examining violence and inequality in the archaeological record. Each case study is summarized and the overall tone, impact and relevance of the volume is discussed.


—The transcriptional regulatory protein nuclear factor- (cid:107) B (NF- (cid:107) B) participates in the control of gene expression of many modulators of the inflammatory and immune responses, including the adhesion molecules E-selectin and intercellular adhesion molecule-1 (ICAM-1). NF- (cid:107) B is found in the cytoplasm complexed with its inhibitory protein I (cid:107) B. On activation, I (cid:107) B is phosphorylated and degraded, thereby freeing NF- (cid:107) B for translocation to the nucleus. We have generated populations of endothelial cells expressing wild-type and a proteolysis-resistant mutation of I (cid:107) B that is lacking the 36 N-terminal amino acids (I (cid:107) B (cid:68) N) in order to examine the effects of expression of the mutated I (cid:107) B on tumor necrosis factor- (cid:97) (TNF- (cid:97) )–induced E-selectin and ICAM-1 expression. Wild-type and I (cid:107) B (cid:68) N were introduced into primary endothelial cells using retrovirus infection followed by selection with G418. The I (cid:107) B (cid:68) N protein remained at untreated control levels in endothelial cells treated with TNF- (cid:97) and also remained complexed with the NF- (cid:107) B family member p65. Furthermore, TNF- (cid:97) –induced NF- (cid:107) B DNA binding activity was inhibited in the population of endothelial cells expressing I (cid:107) B (cid:68) N. That population of cells was also refractory to upregulation of E-selectin and ICAM-1 after treatment with TNF- (cid:97) . The use of a truncated I (cid:107) B (cid:97) protein to prevent NF- (cid:107) B–mediated gene expression provides a novel and specific approach for investigating the role of NF- (cid:107) B in processes associated with adhesion molecule expression during inflammation. ( Circ Res . 1998;82:314-320.) in equilibration After the final and a gentle spin to remove the the supernatant was removed, and beads were resuspended in SDS sample loading buffer and heated for 5 at 100°C. The supernatant was then used for Western blot analysis on a 12% denaturing SDS-polyacrylamide gel. The retrovirally encoded I (cid:107) B (cid:97) proteins were detected using the SC-847 antibody. Coprecipitated NF- (cid:107) family were detected with a specific rabbit polyclonal that recognizes NF- (cid:107) p65 (Santa Cruz Western blots were developed using an alkaline phosphatase–conjugated secondary antibody (Bio-Rad). using containing an B site B two 3 and 5 3 radiolabeling - 32 P]dCTP fragment of DNA polymerase NF- B two complementary oligonucleotides correspond- ing to positions 177 to 189 of the ICAM-1 promoter and end-labeling with - 32 P]ATP using T4 reactions (20 L) containing 10 (cid:109) g of nuclear 2 g poly(dI-dC) in 10 mmol/L mmol/L NaCl, 4 mmol/L DTT, 1 mmol/L EDTA, 4% glycerol were incubated minutes at 4°C. Binding of of P-labeled


Data security is crucial for all businesses as payment, personal files, bank account details all of this information is often impossible replace if lost and dangerous in the hands of criminals. Data lost due to disasters such as a flood or fire is devastating, but losing it to hackers or a malware infection can have far greater consequences. Encryption process are handle and protect your data is control to the security of our business and the privacy expectations of customers, employees and partner. Encryption is a powerful defensive weapon for free people. It offers a technical guarantee of privacy, regardless of who is running the government. It's hard to think of a more powerful, less dangerous tool for liberty. Cyber security is not a single problem, but rather a group of very different problems involving various sets of threats, targets and costs. As a result, legal policy analysis must begin by identifying the particular problem to be considered. It is clear that cyber attacks impose heavy costs and that the rate of attack is increasing. Security vulnerabilities continue to be discovered and disclosed in widely-deployed software at a great rate. Internet-connected computer users generally fail to take basic steps to patch the vulnerabilities in their software and to safeguard their systems from malicious code. Despite the large accumulated losses and warnings of more serious dangers, the internet remains a place of cyber insecurity. Pretty Good Privacy (PGP) is data encryption and decryption software that provides cryptographic privacy and authentication for data communication. PGP is often used for signing, encrypting and decrypting texts, e-mails, files, directories and whole disk partitions to increase the security of e-mail communications.


Objectives To discuss the link age between nonalcoholic fatty hepatic disease and malignant tumors. Data sources MEDLINE databases (PubMed, Medscape, Science Direct) and every one material obtainable on the net from 1998 to 2019 were searched. Study selection The initial search included 88 articles, of that 34 met the inclusion criteria. The articles studied the linkage between nonalcoholic fatty hepatic disease and malignant tumors. Data extraction If the studies failed to fulfill the inclusion criteria, they were excluded. Study quality assessment enclosed whether or not moral approval was gained, eligibility criteria nominative, applicable controls and adequate data, and outlined assessment measures. Data synthesis Comparisons were created by structured review with the results tabulated. Findings In total 23 probably relevant publications were enclosed. The studies indicated that nonalcoholic fatty hepatic disease plays an important role in development of different types of malignant tumors, including hepatocellular carcinoma, colorectal carcinoma, and prostate cancer. Conclusion Nonalcoholic fatty liver disease (NAFLD) is a complicated multifactorial disease closely interrelated with obesity and type 2 diabetes, and shares with them a significant enhanced risk of several types of malignant tumors. Further studies are necessary to better define patients with high-risk NAFLD and effective screening strategies, but we encourage health care providers taking care of patients with NAFLD to be vigilant for any signs and symptoms of cancer, particularly hepatocellular and colorectal cancers, and refer the patients for further assessment and management.


Cocoa butter is the characteristic fat ingredient of chocolate industries, presenting itself as the most important component in all formulations. Its crystallization is a critical factor associated with the structure and properties of many confectionery foods. The stability of rich-fat processed products is influenced by changes in crystallization processes. With respect to these characteristics, the crystallization kinetics, which involves the stages of nucleation and crystal growth, profoundly influences the final solidification of cocoa butter. Polymorphism can be defined as a result of differences in crystal packing. Depending on the origin of cocoa almonds, the chemical composition of cocoa butter may vary and this reflects mainly on crystallization rates and polymorphic changes during the processing steps. In this work, the parameters of crystallization kinetics and polymorphism of three industrial standardized cocoa butter samples and cocoa butter samples from three different Brazilian states were compared. The crystallization kinetics was performed by nuclear magnetic resonance and characterized according to induction period (τSFC), maximum solid fat content (SFCmax) and time required to obtain 50% of maximum solid fat content (t1/2SFCmax). The original Avrami equation was used to model the crystallization process. The polymorphic habit was determined through X-ray diffraction. τSFC values ranged from 6 to 8 minutes for the evaluated samples and proved to be identical and slightly lower for the industrial blends of cocoa butter. The percentages for the SFCmax varied between 78.4 and 89.5% for all samples. In particular, the values of t1/2SFCmax and the Avrami parameters differentiated the industrial blends and the Brazilian samples on the crystallization rate. The standardized blends were characterized by higher crystallization rates and more uniform structuring, suitable for use in tropical areas. All evaluated samples exhibit the polymorphic form V, desirable for the production of chocolates, in the conditions of analysis.


Issue 22:2 represents the aims and scope of JRIP well. It is an issue concerned with the mother's psychological state during one of the most reproductively important phases of her life, and how she perceives her foetus during pregnancy and infant following delivery. The focus of the papers concerns the interactions between these two lives, but using different populations. These range from depressed, non-depressed and substance addicted mothers, to surrogate and recipient mothers in such arrangements. We start this issue with a paper by Sjörgen, Edman, Widström, Mathiesen and Uvnäs-Moberg. Their paper in part assesses the utility of a modification of the Maternal Foetal Attachment Scale (MFAS) for use in a Swedish population, and relates these data to personality traits in women experiencing their first pregnancy. Women were randomly allocated to the 13 week gestation or the 36th week gestation group, and differences in attachment scores between these two groups were observed. Regression analyses between attachment and personality showed high social desirability on the personality scale and a proneness to guilt were significantly associated with higher attachment and late phase of pregnancy. Sharp and Bramwell use a psychoanalytic approach of mothering orientation for the antenatal prediction of postnatal depressed mood. They used a modified version of the third trimester Facilitator (who experiences pregnancy as the culmination of her feminine identity) Regulator (who views pregnancy as a tedious means of getting a baby) Questionnaire to assess mothering orientation in a British population. They found that women who reported a Regulator orientation were at increased risk for postnatal depression, over and above antenatal depression symptom level. The results of a study by Pajulo, Savonlahti, Sourander, Helenius and Piha, on maternal representations and interactive behaviour, are described in a brief report. These authors used 12 mother-baby pairs from residential treatment units for substance abusers. Maternal representations were assessed during late pregnancy and early mother-infant interactions and depressive symptoms were assessed at 6 months postpartum. A negative perception of the infant, a negative view of the infant's father and their perceptions of their own mother as mother were all associated with problem areas in maternal interaction and postnatal depression. In line with much of the literature on mother-infant perceptions, Pajulo et al. used observational methods to understand mother-infant interactions, but the next paper incorporated in this issue used a questionnaire method to address similar factors. Scopesi, Viterbori, Sponza and Zucchinetti's study concerns the validation of a JOURNAL OF REPRODUCTIVE AND INFANT PSYCHOLOGY, VOL. 22, NO. 2, MAY 2004, pp. 55–56


Hypothesis / aims of study Patients with overactive bladder (OAB) and urge urinary incontinence (UUI) treated with oral muscarinic antagonists, such as oxybutynin or tolterodine, report dry mouth as the most common side effect. Independent studies have also noted the poor longterm patient compliance with anti-muscarinic therapy, and this is believed to be largely due to dry mouth. In addition, dry mouth is often observed to be a dose-dependent side effect in clinical practice, frequently limiting the use of high doses of antimuscarinic agents as a means to obtain greater efficacy in bladder control. The purpose of this small study was to examine the potential of oral pilocarpine, a short-acting muscarinic agonist and salivary stimulant, as means of reducing or eliminating the dry mouth side effect in subjects with OAB and UUI receiving tolterodine treatment. The safety and efficacy of standard doses of tolterodine given in combination with pilocarpine was assessed.


The Parisian Faubourg Saint Germain and perhaps the Rue de la Paix and the boulevards seemed the adequate measure of luxury to all of the snobs. The old colonial shell of the Latin American cities little approximated such scenery. The example of Baron de Haussmann and his destructive example strengthened the decision of the new bourgeoisies who wished to erase the past, and some cities began to transform their physiognomy: a sumptuous avenue, a park, a carriage promenade, a luxurious theater, modern architecture revealed that decision even when they were not always able to banish the ghost of the old city. But the bourgeoisies could nourish their illusions by facing one another in the sophisticated atmosphere of an exclusive club or a deluxe restaurant. There they anticipated the steps that would transmute "the great village" into a modern metropolis. —José Luis Romero


In the present invention, the use thereof for the production of water-based UV- curable dispersions and coatings, especially coatings for wood-based substrate is provided. Dispersion of the present invention, a) at least said at least one polyisocyanate urethane, biuret, already oligomers poly nook Saadi-triazine-dione and / or isocyanurate of hexamethylene diisocyanate having isocyanurate structural units isocyanate 1 kinds of polyisocyanate, b ) (meth) monoacrylate with at least one containing a group a hydroxy-functional compound, c) mixing the (potentially) ionic having a hydrophilic effect based on the group, an isocyanate of the one or more added-1 containing a reactive group or more kinds of components c1), and / or containing non-ionic hydrophilic functional group, and an isocyanate of the at least one additional - at least one comprising a reactive component c2), d) chain extending first longitudinal di-functional and / or multi-functional or more as the amine or hydroxy amine, and e) optionally, other monomers, oligomers, which also optionally may contain an addition of an unsaturated / Or a reaction product of a polymeric material. Polyisocyanate, UV- curable dispersion


In June of 1995, Fleming-Mason Energy Corporation was selected to participate in RER Project 94-4, field testing for the written pole single-phase motor. The site selected was unique in that a phase converter and three-phase motor were already in operation. By installing a written pole motor at this site, head-to-head competition could take place between two of the possible solutions for consumers needing to operate large motor loads on rural, single-phase power lines. This paper addresses the installation, the irrigation system, the phase converter and three-phase motor, the written pole motor, comparative efficiencies, operating costs, and the pros and cons of each of these technologies. Actual field measurements are included.


Background/Aims: The antiatherosclerotic enzyme paraoxonase (PON1) is affected by disease and lifestyle. We investigated the impact of diet in diabetic foot patients from 2 European countries. Methods: Dietary intake and serum PON1 activity, using as substrate paraoxon (paraoxonase) or phenylacetate (arylesterase), were assessed in patients from Bucharest (n = 40) and Antwerp (n = 30) and in 34 healthy controls. Results: The diabetic patients had lower paraoxonase and arylesterase activities than the controls. Arylesterase was lowest in the Bucharest patients, 116 ± 42 U/ml, versus 141 ± 43 and 184 ± 49 U/ml in the Antwerp patients and controls, respectively (p < 0.0005). The Bucharest patients had worse glycemic control, higher blood pressure, lower HDL cholesterol and a diet richer in cholesterol and poorer in monounsaturated fats and fish. In contrast, their median intake of vitamins E and C, folic acid and flavonoids was higher, 82 mg (range: 4–259 mg), versus 28 mg (range: 5–169 mg) aglycone units in Antwerp (p = 0.005). Flavonoid intake predicted arylesterase independently of HDL cholesterol, region and sex (β = 0.27; p = 0.03), and patients with high intake achieved normal levels of arylesterase (30.1 ± 10.0 U/µmol in the highest versus 21.0 ± 8.2 U/µmol total cholesterol in the lowest tertile; p = 0.02). Conclusion: A flavonoid-rich diet is positively associated with PON1 arylesterase activity in diabetic foot patients.


200 ft high dam has tainter-gate controlled ogee spillway that discharges into hydraulic jump-type, energy dissipator with single row of baffles and end sill; damages in concrete of stilling basin were discovered 2 yr after project became operative; evaluation of conditions that are considered to have contributed to damage.


In general, a similarity threshold (i.e., a vigilance parameter) for a node learning process in Adaptive Resonance Theory (ART)-based algorithms has a significant impact on clustering performance. In addition, an edge deletion threshold in a topological clustering algorithm plays an important role in adaptively generating well-separated clusters during a self-organizing process. In this paper, we propose a new parameter-free ART-based topological clustering algorithm capable of continual learning by introducing parameter estimation methods. Experimental results with synthetic and real-world datasets show that the proposed algorithm has superior clustering performance to the state-of-the-art clustering algorithms without any parameter pre-specifications.


► Protocols for creating libraries for RNA-Seq using Illumina's nextgeneration sequencing platforms include preps that utilize either poly-A selected mRNA or Total RNA. ► In addition the preps can also be performed with different types of cDNA synthesis chemistries, some of which are non-stranded and some that preserve the strandedness of the mRNA during cDNA creation, like RNA ligation methods or the incorporation of modified bases like dUTP. ► There are total RNA prep methods that use the RiboZeroTM kit (Epicentre) or the Duplex Specific Nuclease (DSN, from Evrogen) for rRNA reduction. Both of these approaches allow one to make full-length cDNA libraries that are completely independent of the integrity and degradation of the starting RNA material. Since these Total RNA-Seq methods do not use a poly-A selection procedure they allow us to sequence all of the RNA in the library including many non-coding RNAs that can be missed in other gene expression assays. Automated Workflow for RNA-Seq Data Analysis


This paper expounds the necessity of university library's hiring student librarians,analyzes the problems existing in the employment of student librarians,and probes into the countermeasures for improving the activity of student librarians.


Anodising is an important finishing technique used to produce controlled oxide coating on aluminium extrusions which impart aesthetic finish, longer life and resistance to corrosion and abrasion. The anodising process however leads to generation of significant amounts of acid and alkaline waste containing mainly aluminium. Normally these wastes are neutralised producing aluminium hydroxide sludge the disposal of which is problematic. Finex is New Zealand's most recently developed anodising plant established in Hamilton in 2004. During the first period of operation the company was faced with a costly sludge disposal problem. The present project was devised to study their production plant and wastewater treatment plant. A brief study of the sludge showed that even under optimum conditions and with use of polyelectrolyte, gravity settling produced excessive volumes of sludge. The decision was made to install a plate and frame filter press. With the reduction of its bulk by dewatering, the problem of sludge disposal was essentially solved. However the 12 tonnes per week of dewatered sludge production still posed the challenge of devising a way of using the material beneficially. The characteristics of the sludge were determined and routes to commodity products were investigated. Commodity alum was produced in good yield at 4°C by treatment of the sludge with sulphuric acid followed by crystallisation with anhydrous potassium sulphate. The product was very similar to the commercial product. Under basic conditions, sodium aluminate was produced by adding stoichiometric amount of OH . Under acid conditions at the H + /Al(OH)3 stoichiometric ratio of 3, 95% of the aluminium was recovered as aluminium salt solution. When acid addition was less than the stoichiometric ratio of 3, the polyelectrolyte containing sludge showed little tendency to re-suspend. A variety of mechanical and thermal methods was used in an attempt to disaggregate and re-suspend the sludge. These included ultrasonic treatment at 80°C at frequency 14 kHz for 6 hours, autoclaving the sludge in electrical furnace at 150°C for 6 hours, homogenisation at 3000 rpm for 30 minutes at 20°C and mechanical grinding using mortar and pestle at 20°C. The


In this paper, recent progresses in optical analysis of dislocation‐related physical properties in GaN‐based epilayers are surveyed with a brief review. The influence of dislocations on both near‐band edge emission and yellow luminescence (YL) is examined either in a statistical way as a function of dislocation density or focused on individual dislocation lines with a high spatial resolution. Threading dislocations may introduce non‐radiative recombination centers and enhance YL, but their effects are affected by the structural and chemical environment. The minority carrier diffusion length may be dependent on either dislocation density or impurity doping as confirmed by the result of photovoltaic spectra. The in situ optical monitoring of the strain evolution process is employed during GaN heteroepitaxy using an AlN interlayer. A typical transition of strain from compression to tension is observed and its correlation with the reduction and inclination of threading dislocation lines is revealed. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


Congenital nonmelanocytic nevi include epidermal nevi, connective tissue nevi, sebaceous nevi, hair follicle nevi, and proliferations of other dermal and subcutaneous structures including smooth muscle and adipose tissue. Such lesions often involve the skin of the head and neck region and are sometimes associated with syndromes of genodermatosis. Tumors with follicular differentiation include a large variety of lesions that recapitulate various structures of the hair follicle. Numerous classifications of hair follicle tumors are proposed by experts in the field with limited consensus. Hair follicle nevus, or congenital vellus hamartoma, is an extremely rare lesion of the hair follicle with only scattered case reports in the English literature. The lesion most commonly presents at birth as a small papule on the head and neck area and represents a follicular hamartoma with a high degree of differentiation toward the hair follicle. We report another case of 2 hair follicle nevi occurring in the same adult patient. Immunohistochemical profiling of hair follicle tumors, though most useful in differentiating basal cell carcinoma from trichoepithelioma, is also helpful in characterizing the morphology and thus classification of benign follicular neoplasms such as follicular hamartomas and hair germ tumors. As the immunohistochemical features of hair follicle nevus have not yet been evaluated, we additionally report the staining characteristic of this entity using CD34, bcl-2, and CD10 immunohistochemical stains.


Significance Cells exert forces on their environment by contracting actin networks, friction of intracellular F-actin flow, and polymerization when they move, e.g., during tumor metastasis or development. In this context, the relation between adhesion and cell velocity is a general cell-type-independent observation, the investigation of which bears the chance of understanding basic mechanisms. Restricting cell motion to one-dimensional lanes simplifies the problem and allows for comparison to mathematical models. Polymerization at the cell's leading edge drives F-actin network flow and pushes the membrane. The drag of detaching the cell, the membrane, and the cell body resist motion. Since only velocity-controlled forces shape motion, cells can move even across highly adhesive areas without getting stuck. The biphasic adhesion–velocity relation is a universal observation in mesenchymal cell motility. It has been explained by adhesion-promoted forces pushing the front and resisting motion at the rear. Yet, there is little quantitative understanding of how these forces control cell velocity. We study motion of MDA-MB-231 cells on microlanes with fields of alternating Fibronectin densities to address this topic and derive a mathematical model from the leading-edge force balance and the force-dependent polymerization rate. It reproduces quantitatively our measured adhesion–velocity relation and results with keratocytes, PtK1 cells, and CHO cells. Our results confirm that the force pushing the leading-edge membrane drives lamellipodial retrograde flow. Forces resisting motion originate along the whole cell length. All motion-related forces are controlled by adhesion and velocity, which allows motion, even with higher Fibronectin density at the rear than at the front. We find the pathway from Fibronectin density to adhesion structures to involve strong positive feedbacks. Suppressing myosin activity reduces the positive feedback. At transitions between different Fibronectin densities, steady motion is perturbed and leads to changes of cell length and front and rear velocity. Cells exhibit an intrinsic length set by adhesion strength, which, together with the length dynamics, suggests a spring-like front–rear interaction force. We provide a quantitative mechanistic picture of the adhesion–velocity relation and cell response to adhesion changes integrating force-dependent polymerization, retrograde flow, positive feedback from integrin to adhesion structures, and spring-like front–rear interaction.


A notion of reducibility in finite posets is studied. Deletable elements in upper semimodular posets are characterized. Though it is known that the class of upper semimodular lattices is reducible, we construct an example of an upper semimodular poset that is not reducible. Reducibility of pseudocomplemented posets is studied.


The necessity and feasibility of legislating climate resources protection single law were summarized in this paper,and the basic ideas of this single law were formed in terms of the empirical analysis,value analysis,economic analysis and historical analysis methods.The results indicated that there was a necessity and feasibility for legislating single law to protect climate resources in China.This law should make clear the basic idea,namely,"safeguard the ecological equality and national ecological security",promote the economic development and maintain the ecological balance.According to those mentioned-above,the basic principle,basic system,management regime and legal liability of the law would be established.


The manner in which infants react to aircraft noise was investigated at Itami City, located at the Osaka International Airport. The subjects were 188 babies whose mothers had moved to Itami City from quiet places, who were classified into the following four groups. Groups I and II were composed of 77 and 45 infants whose mothers came to Itami City before pregnancy or during the first five months of pregnancy, respectively. Groups III and IV were composed of 22 and 44 infants whose mothers came to this City during the latter five months of pregnancy or after childbirth, respectively. In Groups I and II, over 48% of the babies slept soundly and less than 13% awakened and cried on exposure to aircraft noise. On the other hand, in Groups III and IV, less than 15% slept and 50% awakened at the noise. The differences in reactions between Groups I and II and Groups III and IV were obvious and, on the basis of these differences in reactions, it is hypothesized that during the first five months of pregnancy, acous...


The detailed discretization of contact zones with contact stiffness based on real physical characteristics of contact surfaces can produce stiffness terms which induce ill-conditioning of the global stiffness matrix. Moreover the consistent treatment of frictional behaviour generates non-symmetric tangent stiffness matrices due to the non-associativity of the slip phase. Other non-symmetries are due to the coupling terms and to the dependencies on various parameters that can be involved. To overcome these difficulties almost consistent techniques based on two-step algorithms have been proposed in the past. Here an augmentation technique is proposed which takes into account micro-mechanical effects, and permits the symmetrization of the tangent stiffness during frictional slip phase.


On Resolution Guyot, in the Mid-Pacific Mountains, two major intercalations of oolitic limestone have developed, one of latest Hauterivian-Barremian age, which rests directly on edifice basalt, and the second of Aptian age, which is sandwiched between lagoonal-peritidal carbonate sediments. Both oolite packages may be interpreted as the sedimentary response to an increase in the generation of accommodation space; in the first instance, probably related to high rates of basement subsidence, in the second, to a probable eustatic rise in sea level. The ooids vary in structure from micritic and featureless through micritic and concentrically laminated to radial and commonly show combinations of these fabrics. Radial cortical structures, however, predominate. Although oolitic sediment is extraordinarily rare in the Pacific Ocean today, other records show that it was a widespread facies capping many volcanic edifices during the Cretaceous.


To investigate mannose-binding lectin(MBL)and CRP levels in children with Mycoplasma pneumonia(MP).The serum MBL and CRP levels were measured by nephelometry and ELISA. The results showed that MBL levels(3.64±1.72mg/L)and CRP(21.44±15.02mg/L)in 57 infected children with MP were significantly higher than that of control group﹙P 0.001﹚.The MBL levels in children(≤8 years) were significantly lower than that in children(8 years).There was significant difference in MBL levels between 8 recurrent respiratory tract children and other infected children with MP(2.02±1.21mg/L vs 3.95±1.63mg/L,P 0.01﹚. The CRP levels in infected children had declined in recovery phase . It suggested that the levels of MBL and CRP may be the monitoring indicator showing innate immune function in infected children with MP and it may be favourable to estimate curative effect by dynamicly detection.


The high-performance scan conversion we developed provides superior image quality even for low ultrasound scanning line density. TV pixel data is generated by linear and third — order interpolation, linear interpolation (bi — linear interpolation) having been employed conventionally. The result of experiments showed that this method reduces ridge artifacts produced along the scan line in conventional bi — linear interpolation. Our improvement in the third-order interpolation algorithm enabled the circuit size to be reduced to a practical level for real-time equipment applications.


Objectives: To compare the outcomes of two different surgical treatments for the management of isolated closed Mason Type 2 radial head fractures. Design: Retrospective study. The Student t test and McPearson chi-square test were used to evaluate whether there was a significance difference between the groups. Patients: Fifty-nine patients with isolated Mason Type 2 radial head fractures. Intervention: Twenty-four patients treated with radial head excision (Group I) and 35 treated with open reduction and internal fixation (Group II). Main Outcome Measurements: Clinical outcomes were assessed using the Broberg and Morrey functional rating scores and the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire. Orthogonal radiographs were performed on both the elbow and the wrist; these were assessed for the presence of arthritis, heterotopic ossification, and the degree of proximal radial migration. Results: The length of postoperative follow-up was 157 ± 61.84 months (Group I) and 125 ± 39.09 months (Group II). The Broberg and Morrey functional rating score was 86.21 ± 6.10 points and 95.09 ± 4.78 points, respectively. The DASH score was 21.82 ± 6.01 points and 2.81 ± 2.73 points, respectively. Radiologically moderate or severe osteoarthritis was present in the elbows of nine patients in Group I and only two patients in Group II. Conclusions: Patients with isolated Mason Type 2 radial head fractures treated by open reduction and internal fixation (Group II) had less residual pain, greater range of motion, and better strength than patients treated by radial head excision (Group I). Additionally, Group II had a lower incidence of severe posttraumatic arthritis, which contributed to improved DASH and Broberg and Morrey functional scores. These results support open reduction and internal fixation as the treatment of choice for these fractures. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.


We present a case of a chronic and undetermined low back pain in an elderly female patient. The MRI was crucial to characterize a high cellularity mass involving the vertebral body and the surrounding structures in a misleading diagnosis. A discussion of the imaging findings and differential diagnosis of a rare case of spinal Chordoma in a high lumbar position (L2) is provided as follow.


Immigrant students of secondary school age face a number of obstacles as they make the transition to schooling in the United States. In addition to adjusting to a new country and school system, they must also learn academic content in a new language. Because these students come from a variety of ethnic, educational, and economic backgrounds, representing a host of cultures, languages, and educational needs, it is often difficult to provide instruction tailored to their specific needs.


A photoconductive Terahertz (THz) emitter based on low-temperature-grown GaAs and integrated with Bragg mirror is presented. The emitter exhibits improved tera- hertz emission efficiency due to the increased pumping light absorption in the Bragg mirror assisted resonant cavity, due to spatial confinement of the photocurrent, and due to optimized photoconductive response. In this contribution, we report on a low-temperature-grown GaAs (LT GaAs) based photoconductive THz emitter integrated with a Bragg mirror. This design improves the generator's THz output power by about one order of magnitude. The optical resonance and the confinement of the photogenerated carriers in the high electric field region of the LT GaAs layer are responsible for the observed enhancement of the THz emission. In addition, we have focused on optimization of the growth temperature of the LT GaAs layer with respect to a maximum photoresponse of the material and a maximum break- down field. It is known that annealed LT GaAs changes its properties (resistivity, carrier lifetime) with the growth temperature. Our experiences from THz emission experiments suggest a decrease of the output THz power when the growth temperature is lowered. Therefore, we designed and tested a multilayer LT GaAs structure to increase the per- formance of the THz emitters.


In a long-term follow-up of 47 Yemenite patients with benign familial leucopenia, the mean white-cell count was 4,578 with a standard deviation of 940. During bacterial infections, the average leucocyte increment was the same in leucopenic as in non-leucopenic subjects, leading to total leucocyte counts in the normal range in previously leucopenic subjects. The marked degree of variability makes clinical interpretation difficult when leucocyte counts are found between levels standardised as normal in sick patients previously known to be leucopenic.


We study interacting ultracold atoms in a three-dimensional (3D) harmonic trap with spin-selective dissipations, which can be effectively described by non-Hermitian parity-time ($\mathcal{PT}$) symmetric Hamiltonians. By solving the non-Hermitian two-body problem of spin-1/2 (spin-1) bosons in a 3D harmonic trap exactly, we find that the system can exhibit third-order (fifth-order) exceptional point (EP) with ultra-sensitive cube-root (fifth-root) spectral response due to interaction anisotropies in spin channels. We also present the general principle for the creation of high-order EPs and their spectral sensitivities with arbitrary particle number $N$ and arbitrary spin $s$. What is even more interesting is that with spin-independent interactions, the EP order of bosons can be as high as $2Ns+1$, and the spectral response around EP can be as sensitive as $\sim \epsilon^{1/(2ks+1)}$ under a $k$-body interaction anisotropy. These results could provide a convenient route towards more powerful sensor devices in spinor cold atomic systems.


The focus of the presented work is visualization of routes of objects that change their spatial location in time. The challenge is to facilitate investigation of important characteristics of the movement: positions of the objects at any selected moment, directions, speeds and their changes with the time, overall trajectories and those for any specified interval etc. We propose a dynamic map display controlled through a set of interactive devices called time controls to be used as a support to visual exploration of spatial movement.


A Dissertation Submitted to the School of Public Administration and Management in Partial Fulfillment of the Requirements for the Award of Degree of Masters of Science in Human Resource Management (MSc HRM) of Mzumbe University.


House reservoir of liquid upright vacuum cleaner of the present invention is provided to be mounted to the cylinder mounting portion of the liquid upright cleaner is certain space body and, formed on one side of the body and additional inlet of the connecting pipes and the fan motor connection comprising a inside connecting hoses installing a suction passage through which contaminated number suction intake, is formed to be communicated with the upper end of the suction passage in the inner upper side of the portion having can be the collection chamber, and the contaminated contamination collection chamber constant space that can be collected not contaminated therein through the opening and closing means for opening and closing parts of the outlet section collecting contaminated water and, the opening means is to collect contaminated water chamber to the upper inside of the contaminated water collection chamber to the upper surround are formed to communicate with the contamination of the small amount is collected in the collect chamber contamination is composed of a number of open-close means to protect the chamber to prevent a switching means is not operated, can collect chamber contamination during cleaning By blocking the opening and closing means is a malfunction by the backlash gathering contamination can flap of which, in the number of large amounts of contamination in the interior of the house reservoir can be collected, is made as a cleaning operation desired.


ABSTRACT Disposal of ashes from agro-industrial waste has become an important issue that can cause serious environmental problems. These materials may be used in agriculture for soil fertility improvement and carbon sequestration. The effect of applying bagasse ash (BA), rice husk ash (RHA), and RHA mixed with fly ash (MA) to wheat was evaluated on soil organic carbon (SOC) and microbial activity in a loamy sand soil after four years of wheat-rice cropping. BA application resulted in C accrual at 525 kg ha−1 y−1 in soil, whereas RHA and MA did not have a significant effect. BA increased coarse particulate (cPOC) and mineral-associated organic matter (MinOC) and extractable C pools viz. hot water soluble, potassium permanganate (KMnO4)-oxidizable, easily oxidizable, non-oxidizable, and microbial biomass C. BA application also improved overall microbial and oxidative activity and stimulated fluorescein diacetate (FDA), dehydrogenase, and cellulase enzyme activities in soil. Application of RHA though did not lead to net C sequestration, yet it increased dehydrogenase and cellulase activities. Compared to unamended soil, MA application increased MinOC and FDA activity in soil. After 4 years of their application, none of the ashes adversely influenced soil biological activity expressed in terms of enzyme activities suggesting that these ashes can be disposed to agricultural soils. However, effects of their long-term application on soil biological processes need to be further investigated.


At its March 23, 2020, session, the Supreme Court denied review in five petitions on the Appellate Docket and in the 5000 series, which is sometimes called the in forma pauperis docket. The summary below lists the petitions on the Appellate Docket in which the court granted review, took summary action, or denied review. For each petition, there is given (1) its docket number and caption; (2) a citation to the lower court's opinion or order; (3) the ruling of the court below; and (4) the principal questions presented if the petition has been granted review. Other orders appear only in the journal of proceedings elsewhere in this issue of Law Week.


In this article, we highlight a numerical investigation on n-AZO/p-Cu2O solar cell based Analysis of Microelectronic and Photonic Structures software. The natural p-type Cu2O materials distinguish by the medium bandgap energy, the low doping concentration of carriers and the high absorption coefficient (>104 1/cm). The n-type AZO (Al-doped ZnO) materials distinguish by the wide bandgap and the heavy doping concentration of carriers. Metal oxide heterojunction solar cells are being fabricated and used for alternating the failed metal oxide homojunction solar cells which had deeper energy conversion efficiency to the point of lack. The AZO/Cu2O structure promotes to design low cost solar cell devices. The investigated cell is an n-p heterojunction structure made of the two different metal oxide semiconductors: the window AZO layer and the absorber Cu2O layer. By varying the temperature, the open circuit voltage (VOC), the short circuit current (JSC), the fill factor (FF) and the efficiency of AZO/Cu2O solar cell were investigated and optimized.


When a loss-of-main occurs on the frontier of a microgrid, it is possible to supply the loads by intentional islanding, which improves the continuity. It means a distributed energy resource could maintain voltage and frequency with the appropriate control. If the loss-of-main occurs, the detection and the transition between operation modes must be done as fast as possible to decrease the transient. However, too sensitive methods can cause an incorrect control switch. Thus, this paper analyses the impacts of an improper change of control, from grid connected to the islanded control mode, in a distributed energy resource based in voltage source inverter. It is used the IEEE 34 nodes test feeder modeled in the Alternative Transients Program. The results show that if an improper change of control occurs, the distributed energy resource and grid are very affected.


Motivated by the study of several problems in algebraic graph theory, we study finite primitive permutation groups whose point stabilizers are soluble. Such primitive permutation groups are divided into three types: affine, almost simple and product action, and the product action type can be reduced to the almost simple type. This paper gives an explicit list of the soluble maximal subgroups of almost simple groups. The classification is then applied to classify edge‐primitive s‐arc transitive graphs with s ⩾ 4, solving a problem proposed by Richard M. Weiss (1999).


OBJECTIVE
To describe the results of an outcome survey of 18 cases of pediatric lymphangioma with dyspnea from encroachment on the tongue base, parapharyngeal space, and/or larynx.

DESIGN
Retrospective review of files from January 1983 to September 1998.

SETTING
Pediatric otolaryngology departments from 2 referral centers.

PATIENTS
Eighteen patients were treated. The average age at initial surgery was 22 weeks (median, 5 weeks). All presented with at least unilateral suprahyoid and infrahyoid cavernous (microcystic) lymphangioma. The tongue base was involved in 11 patients, the parapharyngeal space in 12, and the larynx in 8.

INTERVENTIONS
Neck dissection was performed initially in all patients. Tracheotomy was performed in 9 patients (50%). Macroglossia was treated by V glossoplasty. Parapharyngeal extensions were treated by cervicotomy or endoscopy, and larynx and tongue base extensions by carbon dioxide laser photocoagulation. Supraglottic laryngectomy was performed in 2 patients.

MAIN OUTCOME MEASURES
Residual disease, decannulation, duration of tracheotomy, and persistent respiratory symptoms.

RESULTS
The average follow-up was 4 years postoperatively. One postoperative death occurred. Sixteen (94%) of the remaining 17 patients had residual lymphangioma. Eight (89%) of the 9 patients with tracheotomy underwent decannulation (average duration, 22 months). Ten patients had persistent symptoms, and 6 were asymptomatic.

CONCLUSIONS
Involvement of the upper airway seems to be the determining prognostic factor in extensive lymphangioma. Patients with dyspnea by external compression of cervical lymphangioma on the airway responded well to surgery. Aggressive surgical treatment did not seem to significantly improve the prognosis in patients with intrinsic involvement of the upper airway. The natural evolution of untreated massive lymphangioma has not been documented. Less aggressive, symptomatic therapy may be an alternative to avoid mutilating surgery in patients with intrinsic involvement of the airway.


10021 Background: Telomeres are composed of tandemly repeated DNA sequences (TTAGGG) and specific binding proteins located at the ends of eukaryotic chromosomes. They stabilize chromosomal ends; telomere shortening is an important mechanism of genomic instability and can lead to end-to-end chromosomal fusion, rearrangements and cell death. Here we evaluate the hypothesis that telomere shortening contributes to the development of prostate cancer (CaP).

METHODS
We used telomeric, centromeric and chromosome specific peptide-nucleic acid probes with z-stacked quantitative fluorescence in-situ hybridisation analysis to initially analyse 15 radical prostatectomy specimens and then subsequently sextant core biopsies from 80 men obtained in 1998-2001 containing high-grade prostate intraepithelial neoplasia (HPIN) only. The biopsy cohort outcome is blinded to prevent experimental bias and has a minimum follow-up of 2 years with 41 men diagnosed subsequently with CaP and 39 men without CaP on rebiopsy. Regions of interest were identifying with an overlying haematoxylin and eosin slide.

RESULTS
We found a significant decrease in telomere length in both HPIN and CaP in comparison to normal prostatic epithelium accompanied by elevated rates of aneusomy. Telomere erosion in HPIN was more common in regions of the prostate-containing CaP. We now have analyzed ∼4000 cells of matching HPIN and surrounding stroma. Preliminary analysis demonstrated that the median telomere length in HPIN is approximately 27% of the surrounding stroma with upper and lower quartiles being 16% and 38% respectively. Logistic regression analysis is in progress to determine whether the length of the shortest telomeres or the average telomeric length in a sample predicts for subsequent diagnosis of CaP. Secondary analyses are examining the effect of telomere length on the interval to the diagnosis of CaP, the effect of age on telomere length and the eventual Gleason score.

CONCLUSIONS
Analysis of telomere length holds great promise for developing improved prognostic markers in prostatic carcinogenesis. This is a first of its kind study in the field. No significant financial relationships to disclose.


Eastern Bering Sea shelf walleye pollock (Theragra chalcogramma) abundance and distribution in midwater were assessed between 9 June and 7 August 2009 using acoustic-trawl techniques aboard the NOAA ship Oscar Dyson. The survey also assessed walleye pollock in the Cape Navarin area of Russia. Results showed that ocean conditions were cold in 2009, as in the previous 3 years, compared to 2001-2005. Fewer pollock were observed east of 170° W than in 2008, and a larger percentage of those were inside the Steller sea lion Conservation Area (SCA) than outside the SCA (79% in 2009, 70% in 2008). The majority of the pollock biomass in the U.S. Exclusive Economic Zone (EEZ) was located to the west and northwest of the Pribilof Islands between the 100 m and 200 m isobaths. Estimated pollock abundance in midwater (between 16 m from the surface and 3 m off bottom) in the U.S. EEZ portion of the Bering Sea shelf was 8.08 billion fish weighing 0.924 million metric tons (t); in the Russian EEZ, there were 9.67 million fish weighing 0.005 million t (0.6% of the total midwater biomass). East of 170° W, (9.6% of total biomass) the predominant length mode was 55 cm both inside and outside of the SCA. In the U.S. west of 170° W (89.8% of total biomass) dominant modal lengths were 13, 31, and 23 cm, respectively. In Russia, modal lengths were 43, 51, and 29 cm, with proportionally more adults and fewer juveniles than in the adjacent western U.S. EEZ. Age results indicated that inside the U.S. EEZ, juvenile walleye pollock (ages-1, -2, and -3) were dominant numerically (64%, 10%, and 21%, respectively) and represented 63% of the total biomass. Adult pollock (ages 4+) totaled 6% of the population numerically and 37% of the total biomass. Vertical distribution analyses indicated that 93% of adult biomass was within 40 m of the seafloor. Juveniles were found both near the seafloor and higher in the water column; 17% of juvenile biomass was within 50 m of the surface. Three-dimensional size and shape patterns of the juveniles are described using data collected with a calibrated multibeam sonar, and variability in these patterns are explored as a function of ontogeny. Finally, a new euphausiid index of abundance computed from backscatter at four frequencies (18, 38, 120, and 200 kHz) is


Objective To investigate the effect of short stature homeobox (SHOX) gene promoter-372G →A mutation on the promoter activity and its mechanism.Methods The luciferase report gene vectors containing human SHOX gene promoter-372G or -372A were contructed.Their transcription activities were detected in chicken chondrocytes.Double-stranded DNA probes containing-372G or-372A were produced by PCR,and used for detecting the affinity with nuclear transcription factors by electrophoretic mobility shift assay(EMSA).Results The transcription activity in a-372A promoter construct was significantly higher than that in the wild type-372G (P<0.01).The result of EMSA showed that-372A gene mutation resulted in loss of the binding affinity to nuclear transcription factors.Conclusion The-372A mutation increases SHOX promoter activity with decreased DNA binding affinity to transcription factors,which may contribute to impaired long bone growth in patients with idio pathic short stature.

Key words:
Idiopathic short stature; SHOX gene; Function; Polymorphism,genetic


Rough rice drying plays an important role in post-harvest practices. Excessive losses can be avoided if drying had conducted properly. Head rice yield (HRY) is a commonly accepted standard for measuring rice milling quality. After harvesting, in major rice producing regions of Iran, there would be delayed rough rice drying and milling due to great deals of produced paddy and low capacity of rice milling plants. This research aimed to investigate the effect of various drying dates on milling recovery head rice yield. The experiments were conducted on five different dates of 0, 15, 30, 60, and 90 days after harvesting and two long grain cultivars of Hashemi (local) and Khazar (improved). The results revealed that cultivars and drying dates had significant (p<0.01) effects on head rice yield. Head rice yield for Hashemi had a decreasing trend under delayed drying dates whereas there was not such a circumstance for Khazar. The highest head rice yield (58.78%) obtained when Hashemi dried immediately after harvesting but for Khazar (57.44%), when it was dried by the most delay.


A plasma processing apparatus comprises a chamber, and an upper electrode and a lower electrode, parallelly provided in the chamber to oppose each other at a predetermined interval, for defining a plasma generation region between the electrodes. An object to be processed is mounted on the lower electrode. RF powers are supplied to the electrodes, so that a plasma generates between the electrodes, thereby performing a plasma process with respect to the object to be processed. A cylindrical ground electrode is provided around the plasma generation region in the chamber, for enclosing the plasma in the plasma generation region, and has a plurality of through holes for passing a process gas.


We previously reported that primary cells derived from rat dental pulp exhibit pluripotency, and that stem cell factors such as Stro-1, Ssea-1, Nanog, and Oct3/4 are expressed in these cells. In addition, downregulation of some factors is observed during lineage differentiation. We hypothesized that stem cell markers including OCT3/4, SOX2, and NANOG would be expressed in human oral tissue-derived primary cells. To further evaluate the expression of pluripotent stem cell factors in primary cells derived from human oral tissues, we quantitatively examined the expression of OCT3/4, SOX2, and NANOG in six primary cell lines derived from human gingival fibroblasts, human periodontal ligament fibroblasts, and human oral keratinocytes. Differential expression of OCT3/4, SOX2, and NANOG was detected in primary cells derived from various types of human oral tissue. Moreover, these cells were found to harbor multiple copies of all three genes. Levels of OCT3/4, SOX2, and NANOG correlated well with each other; in primary cells expressing low levels of OCT3/4 and SOX2, the expression of NANOG also tended to be low. The expression of these factors in oral keratinocytes was higher than that in fibroblasts derived from human gingiva and periodontal ligament. This study indicates that primary cells derived from various types of human oral tissues express pluripotent stem cell factors. The results are expected to expand the future reservoir of potential cell sources that are suitable for cell therapy, replacing more controversial sources currently used. Correspondence to: Tadashige Nozaki, Department of Pharmacology, Faculty of Dentistry, Osaka Dental University, 8-1 Kuzuhahanazono-cho, Hirakata, Osaka, 573-1121 Japan; Tel: +81-72-864-3058; Fax: +81-72-864-3158; E-mail: nozaki@ cc.osaka-dent.ac.jp


BACKGROUND
Depressive symptoms are common in older adults. A majority will be seen in primary care. The aim was to study the prevalence of and to explore factors associated with depressive symptoms in elderly primary care patients.

METHOD
In consecutive patients aged 60 years and older attending a Swedish primary care center between February and December of 2003, depressive symptoms were identified as ≥ 13 points on the Montgomery-Asberg Depression Rating Scale-Self-Rated version (MADRS-S). Somatic symptoms measured according to PRIME-MD, age, socioeconomic status, gender, somatic diagnoses, and medication were analyzed in relation to presence of depressive symptoms.

RESULTS
Forty-six of 302 patients (15%) rated themselves in the depressed range. There were no differences between depressed and nondepressed patients concerning socioeconomic status, other illnesses, or medication except for use of sedatives/hypnotics being more common (OR = 2.7, 95% CI = 1.3 to 5.6) in depressed patients. Patients in the group scoring ≥ 13 on the MADRS-S were more likely to have become widowed during the last year (OR = 6.0, 95% CI = 1.7 to 20.8) or to have indicated significant life events (OR = 4.3, 95% CI = 2.0 to 9.0), but were less likely to report having leisure time activities (OR = 0.2, 95% CI = 0.08 to 0.41) or perception of good health (OR = 0.1, 95% CI = 0.05 to 0.3). Patients being treated for depression did not have increased depression scores (OR = 1.4, 95% CI = 0.66 to 3.1).

CONCLUSION
In a group of unselected primary care elderly patients, the prevalence of depressive symptoms was high. Use of sedatives/hypnotics was remarkably common in patients with depressive symptoms. Patients with ongoing treatment of depression did not have increased depression scores, indicating the good prognosis for treated depression in the elderly.


Education is now engaged in a transitional period with respect to new technologies which is unique in its history. No previous technologies which have been proposed to "revolutionize" education hav...


Nyman and Ormerod (2017) show that the machine learning technique of random forests has the potential to give early warning of recessions. Applying the approach to a small set of financial variables and replicating as far as possible a genuine ex ante forecasting situation, over the period since 1990 the accuracy of the four-step ahead predictions is distinctly superior to those actually made by the professional forecasters. Here we extend the analysis by examining the contributions made to the Great Recession of the late 2000s by each of the explanatory variables. We disaggregate private sector debt into its household and non-financial corporate components. We find that both household and non-financial corporate debt were key determinants of the Great Recession. We find a considerable degree of non-linearity in the explanatory models. In contrast, the public sector debt to GDP ratio appears to have made very little contribution. It did rise sharply during the Great Recession, but this was as a consequence of the sharp fall in economic activity rather than it being a cause. We obtain similar results for both the United States and the United Kingdom.


ABSTRACr.-Breeding Loggerhead Shrikes (Lanius ludovicianus) were studied in the Piedmont physiographic region of north-central South Carolina during the breeding seasons of 1986 and 1987. Sixty-three percent of shrike nests were in red cedar (Juniperus virginiana). Shrikes nesting in red cedar fledged one more young per nest than did shrikes nesting in other trees. First nests were significantly lower and somewhat closer to the trunk of the nest tree than were second nests, suggesting that climatic effects during the nesting season affected nest placement. Within 100 m of shrike nests, short-grass habitats (e.g., pasture, hay fields, and residential lawns) predominated, comprising, on average, more than 80% of the area. Short vegetation around nests may result in increased prey availability. The relatively high reproductive success of Loggerhead Shrikes in this study is similar to that reported by researchers elsewhere, and it does not explain the recent decline in shrike populations in the region. Received 29 Sept. 1988, accepted 15 Jan. 1989.


Nano-sized chitosan has been prepared by ball mill (High Energy Milling) with 1500 rpm to determine itsgrainz size and functional group. A nanopowder sample was prepared in the various milling time of the precusor. The milling time were 60, 120, 180, 240, 300 and 360 minutes. The Scanning Electron Microscopy (SEM)images indicated that the microstructures and grain size of as-prepared chitosan changed by increasing the milling time. The average of grain size is 15,1 nm. The Fourier Transform Infra-Red (FTIR) spectra showedthat the -OH bond shifted after milling process. The new C=O roups formedduring the milling process, because of the ordered microstructures in the nano-sized chitosan granules weredestroyed after ball millingThe surface area of the nano-sized chitosan was high, the particles tend to agglomerate since the ionic electrostatic could not prevent to form the agglomeration. The ball milling treatment was an effective method to reduce the grain size of chitosan, and functional groups will not automatically change during the milling process.


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The present paper addresses the problem of estimating returns on financial instruments when there is incomplete information about the instrument's cash flows. The problem is shown to resolve itself as an exercise in numerical analysis. In theory, the true return is obtained as the solution of an integral equation, but since the required functions are incompletely specified, numerical estimating techniques must be applied. Alternative numerical methods are examined, each of which make different assumptions about the time series properties of the financial instrument's cash flows. It is shown that the estimated returns are highly sensitive to these assumptions and thus to the numerical technique used.


This study aims to investigate the interdependence between bicycle mode choice and activity pattern in individual travelers' daily travel activities.Based on household survey conducted in Bengbu,the difference of bicycle usage in multiple trip chains was analyzed.The interested interdependence was captured using the co-evolutionary logit model.Results showed that bicycle was more commonly used in the subsistence-based trip chains than the non-subsistence trip chains.Individuals who chose bicycle as trip mode were more likely to make simple and non-subsistence trip chains.Considering the interactions between bicycle choice and trip-chaining pattern significantly improved the predicting accuracies for the selection of bicycle and trip chain.


A method and system of providing user profiling for an electrical device is disclosed. Face representation data is captured with an imaging device. The imaging device focuses on the face of the user to capture the face representation data. A determination is made as to whether a facial feature database includes user facial feature data that matches the face representation data. User preference data is loaded on a memory module of the electrical device when the face representation data matches user facial feature data in the facial feature database. A new user profile is added to the user profile database when the face representation data does not match user facial feature data in the facial feature database.


In the aftermath of the 2008 elections in the United States, and in the wake of the near collapse of the US economy, it seemed that the political and economic policies of the American Right had been completely discredited and that progressive forces were on the rise. By 2010, however, the Right made an amazing come-back and in many ways re-seized the initiative from the Democrats. How did the Right recover so quickly and what role did the media play in this resurgence? How is the Right's quick recovery related to its access to and political uses of the major means of communication? How do media concentration and ownership affect the propagation of right-wing ideologies? What role did the media play in galvanizing the Tea Party movement? Has the media obfuscated the role of the Christian Right in the Tea Party movement? What role did media play in popularizing right-wing leaders, such as Sarah Palin, Michele Bachmann, and others? How has the development of new technologies affected politics? How is the resurgence of the American Right related to global politics? Do right-wing groups in other countries operate in ways that are similar to the American Right? Finally, what possibilities can be identified for developing and widening cracks in that hegemony by harnessing old and new media technologies?


PURPOSE: An aerial photographing system for preventing image blurs caused by a steering mirror is provided to sense a position of the steering mirror by using an approximate sensor of high resolution and high precision and to precisely control a driving device. CONSTITUTION: An aerial photographing system for preventing image blurs caused by a steering mirror comprises an optical window(110), an image sensor(120), a steering mirror(130), a roll shaft driving module(150), a BSM driving module(160), and a control unit(170). The steering mirror adjusts a reflecting direction of lights incident through the optical window. An approximate sensor senses the movement of the steering mirror or a position caused by shaking. The rolls shaft driving module performs the roll shaft direction driving of the steering mirror. [Reference numerals] (110) Optical window; (120) Image sensor; (130) Steering mirror; (140) Proximity sensor module; (150) Roll shaft driving module; (160) BSM driving module; (170) Control module


To the Editor: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents and accounts for 3% of all pediatric tumors.1 Major RMS subtypes include embryonal rhabdomyosarcoma (ERMS), which is the most common (70%–75% of all cases in children), and alveolar rhabdomyosarcoma (ARMS) (20%–25% of all RMS cases affecting older children).2,3 The ERMS and ARMS are two cytogenetically distinct entities. ERMS has a complex genome that is characterized by whole chromosome alterations, including gains of chromosomes 2, 8, 11, 12, 13, and/or 20 or losses, includingmonosomy 10 and 15,2 while ARMS is characterized by balanced chromosomal translocations involving chromosomes 2 or 1 and chromosome 13.3–6 Note that 70%–80% of ARMS cases showed t(2;13)(q36;q14) translocation resulting in PAX3-FOXO1 fusion, while 20%–25% of cases showed t(1;13)(p36;q14) translocation, resulting in PAX7-FOXO1 fusion.3–6 Spindle cell/sclerosing rhabdomyosarcoma (SSRMS) is a rare entity that accounts for 3%–10% of all RMS cases and may arise at any age.7–9 While SSRMS is currently a well-recognized, morphologically distinct entity, a subset of RMS with spindle cell morphology lacking recurrent genetic abnormalities may represent a variant of ERMS,10 presenting as a differential diagnosis to our case. We present a 13-day-old male child with a right neck swelling at birth. Prenatal and birth histories were unremarkable. Evaluation by magnetic resonance imaging, magnetic resonance angiography, and magnetic resonance venography showed a solid soft tissue mass measuring 3.6 cm (Figure 1), extending from the right retro-auricular area to the scalp and upper neck. The patient underwent biopsy of the mass, followed by complete surgical excision with negative margins and sentinel lymph node dissection. Grossly, the mass weighed 30 g (5.8 × 3 × 2.2 cm) and was well circumscribed, with homogeneous pale tan and rubbery cut surface.Microscopically, therewas low-grade spindle cell proliferation with myxoid background and well-differentiated striated skeletal muscle fibers with some round globoid contours and cross striations (Figure 2). No atypia, anaplastic features, and necrosis were noted. The tumor cells stained diffusely positive for desmin, multifocally positive for myogenin, and negative for S100 protein, OSCAR, CD31, EMA, and CD68. MyoD1 staining showed rare positive cells, most likely excluding a MyoD1-mutant spindle cell rhabdomyosarcoma.Ki-67 showedapproximately 20%nuclear labeling. Fluorescence in situ hybridization analysis using custom bacterial artificial chromosome (BAC) probes showed no abnormalities in the VGLL2, CITED2, SRF, NCOA2, NTRK1/3, BRAF, RET, and MET genes. Next-generation sequencing analysis identified a clinically significant focal loss (∼2Mb, 0.4 copy loss) of 9q22.32 involving PTCH1 (protein patched homolog 1) and FANCC (Fanconi anemia complementation-group C) copy number alterations. The clinical staging was Stage 1 Group 1. According to the ARST0331 treatment protocol, chemotherapy was initiated, comprising vincristine and dactinomycin. Cyclophosphamidewas incorporated after the patient reached 3 months of age. Radiation was not utilized due to the patient's age and low-risk disease. The patient tolerated the treatment, and 16 months from the initiation of therapy, showing no evidence of recurrence ormetastasis. The chromosome 9q22.32-22.33 (4.4 Mb) region harbors several putative tumor suppressor genes, including DNA-damage repair genes like FANCC, XPA (xeroderma pigmentosum A), and the hedgehog pathway associated gene PTCH1.11 Missense mutations, nonsense mutations, and frameshift deletions of the FANCC gene have been reported in various cancers such as the colon, lung, breast, and kidney.12 The FANCC gene is also reportedly altered in 1.14% of rhabdomyosarcoma


Clapper Tongue and Moon Walker were created from research on the coastline fortifications at Berwick-upon-Tweed during the Berwick Gymnasium Fellowship (October 2008-March 2009) funded by Arts Council England and English Heritage.

Clapper Tongue is a 45-kg bronze life cast head and shoulders in the form of a bell suspended from the ceiling, fitted with an electronic strike hammer, ringing on an hourly timer. Cobbing liaised with the Whitechapel Bell Foundry to establish the optimum high copper bronze alloy to achieve a resonant sound for the bell-like sculpture, to account for its unusual non-symmetrical shape. Clapper Tongue also referenced the warning bell tower that was tolled when enemy lines approached the town, part of the area's broader defensive architecture, from artillery ramparts built in 1558 to WWII concrete pillboxes. The title 'Clapper Tongue' refers to the anatomy and anthropomorphism of bronze bells, parts of which are labelled 'neck', 'lip', 'shoulder', and 'clapper tongue.'

Moon Walker (13:15 mins) is a video documenting Cobbing walking backwards in a circle besides the Berwick coastline, with footage reversed so that he appeared to be walking forwards into his footprints in the sand. The performative action engages with Roberts Smithson's theorization of entropy in 'Monuments of Passaic' (1967); namely how earthly material is subject to an irreversible process of erosion and dispersal. The erasure of a 'drawn' line of footprints along the coast in the Moon Walker video also echoes the palimpsest of shifting borderlines between England and Scotland in Berwick.


In this study, we investigated the regions in the alternatively spliced C2 insert of nonmuscle myosin (NM) II‐C conferring unique functional properties to the protein. We used constructs carrying deletions within different regions of C2 in neuronal cells; namely, the polar N terminus, the proline/serine‐rich middle, and the nonpolar C terminus. We compared the wild‐type NM II‐C2 and deletion mutants with respect to ATPase activity, coassembly with NM II‐B, regulation by myosin light‐chain kinase (MLCK), and solubility, to determine the C2 region(s) involved in these processes. In addition, we examined the ability of the mutants to rescue the neurite‐shortening phenotype upon NM II‐C2 knockdown in Neuro‐2a cells. Our data highlight the importance of the polar N terminus in NM II‐C2 function.


Nuisance free vegetable production is a focal topic that has drawn great attention from the Chinese government and the community recently. A great number of people take it for granted that only using organic fertilizers without chemical fertilizers is able to produce the nuisance free vegetables. Therefore, it need more research from different directions to provide scientific evidence to clarify this conception. Radish and garlic were used as the target vegetables to study the (effects) of organic and inorganic fertilizer on nitrate accumulation in the vegetables. Results showed that the significant yield differences of those two vegetables between these three organic fertilizer treatments which had identical N rate, indicated a strong suitability of different organic fertilizers to different vegetables. Nitrate content in the two vegetables was remarkably higher in the early growing stage. Nitrate content in the vegetable applied organic fertilizer only was not always lower than that using inorganic one. Rationally applying, no matter the organic or inorganic fertilizer, was essential to produce low-nitrate bearing vegetable. Rational application of organic fertilizer incorporated with the inorganic could not only improve yield but also reduce nitrate accumulation in the vegetable.


In the present context of oil price down turn and enhanced competitiveness, cost saving becomes more important than ever. As part of cost reduction solutions in offshore projects, it may be envisag ...


Nanoparticles NiFe2-xGdxO4 (x=0, 0.1, 0.2, 0.3, 0.4) ferrite was prepared by solgel combution method. The samples were characterized with X-ray diffraction and SEM measurements. The effect of Gd3+ cations substitution on structure of prepared nanoparticles was investigated. From the analysis, the system was found to be inverse spinel cubic structure. The lattice parameter (a) increases with Gd doping content. . Room temperature DC electrical resistivity decreases .Dielectric properties have been studied in the frequency range of 1 kHz to 5 MHz. Permittivity and tangent loss (tanδ) decreases with the substitution of Gd3+ in parent crystal structure.


This paper mainly addresses the issue of semantic concept drifting in temporal sequences, such as video streams, over an extended period of time. Gaussian Mixture Model (GMM) is applied to model the distribution of under-investigating data, which are supposed to arrive or be generated in batches over time. The up-to-date classifier, which tracks the drifting concept, is directly built on the outdated models trained from the old labeled data. A couple of properties, such as Maximum Lifecycle, Dominant Component, Component Drifting Speed, System Stability, and Updating Speed, are defined to track concept drifting in the learning system, which is applied to determine corresponding parameters for model updating in order to obtain optimal up-to-date classifier. Experiments on simulated data and real-world data demonstrate that our proposed GMM-based batch learning framework is effective and efficient for dealing with concept drifting.


PreviewWhile deaths due to coronary artery disease have declined in recent decades, the recommendation of new cutoff points for defining hypercholesterolemia and the introduction of new lip- id-lowering agents promise even greater reductions. In this article, Dr Naito shares his experience in the use of hypolipidemic agents, focusing on the rationale for treating persons at risk for coronary artery disease, the new National Institutes of Health cholesterol guidelines for defining persons at risk, and treatment with currently available cholesterol-lowering agents. Special attention is given to issues of patient compliance.


A high frequency oscillator comprising a ring type inductive resonator of a microstrip line constituted in a rectangular or annular loop. Capacitors are serially connected to both ends of the line, thereby improving the low-noise, separation and stability characteristics by use of the steep-phase characteristic of the ring-shaped resonator.


Jejungwon(濟衆院) is the first national modern hospital in the history of Korea, and one of the earliest modern institutions. Korean(Choson, 朝鮮)...


Design and method: In 1293 hypertensive patients followed-up for a median of 5.1 years, in a hospital consultation specialized in hypertension, 13 271 consultations were made. At each visit, the list of current antihypertensive treatments has been completed. Demographic data, medical history, clinical parameters with blood pressure measured in a standardized way with an electronic device by automatic measurement were obtained. The TCS was calculated at each visit with 0 in case of therapeutic stability and 1 in the case of change of at least one antihypertensive treatment or its dosage. Data has been anonymized and organized to enable the training and implementation of artificial intelligence to predict the TCS models (gradient boosting trees, Long Short Term Memory).


Michael E. Essington, CRC Press, Taylor and Francis Group, 2nd edition, 2015. 633 pp. ISBN: 9781466573154. $67.96.

The second edition of the book Soil and Water Chemistry: An Integrative Approach is written by M.E. Essington. This book consists of 12 chapters with several illustrations and tables,


Scien- ti c Writing discusses the making of the minutes for the meeting management application using Microsoft Visual Basic 2005. The application program is aimed at organizing the meeting, standardize the format of writing minutes of the meeting is also to facilitate the search and documenta- tion of the results of the meeting


Private Voluntary Organizations in Egypt: Islamic Development, Private Initiative, and State Control, by Denis J. Sullivan. Gainesville: University Press of Florida, 1994. vii + 160 pages. Notes to p. 177. Bibl. to p. 186. Index to p. 191. $29.95. Denis Sullivan's Private Voluntary Organizations in Egypt is a pioneering study analyzing how private voluntary organizations (PVOs) interact with and present a challenge to the economic and political systems operating in Egypt today. Based on interviews in over sixty PVOs, and with officials in both Egyptian and foreign government agencies, the book posits four primary questions. These are: 1) Is social activism against state structures and strictures the solution to Egypt's socioeconomic and political problems? 2) Are Islamic and Christian groups substituting for the government in the realm of socioeconomic development? 3) If so, do these social organizations pose a significant alternative to the government? 4) Does the challenge presented by PVOs threaten the legitimacy of the regime? Sullivan hypothesizes that PVOs both challenge the government's role and threaten its legitimacy. In the course of "testing" these hypotheses, he examines two others. The first is that "small is better" in the sense that small development projects promote more tangible results than do large projects that target larger communities. The second is that "local is more legitimate"- people will more likely work with and listen to people from their own community. Private Voluntary Organizations in Egypt is a well-written, well-organized book that consistently and persuasively argues that PVOs are successful in challenging the state's role in providing social welfare benefits because of the fact that they are both "small" and "local." After broadening his study to compare Egyptian PVOs with those in Africa, Asia, Latin America and the Middle East, Sullivan concludes that Egyptian PVOs are a challenge, but not a threat, to the current system. Egypt's PVOs, and particularly its Islamic PVOs, are poised to challenge the current government to reform itself and to open itself up to greater participation, democratization and economic restructuring. They, furthermore, are in a strong position to influence a successor government if a threat surfaces from another quarter, such as a right-wing or religious military takeover. Sullivan's study lies at the heart of the most pertinent debate in Egypt today. The crux of his research concerns the changing nature of statesociety relations within the context of political turmoil and economic dislocation. To a large extent, this debate revolves around the degree of state control over Egypt's PVOs and the consequent implications for political stability and the success of economic reform. …


The invention relates to a machine interface (1) between a grinding table (2), a vertical mill (3) and a drive (4) of the grinding bowl (2). The machine interface (1) is formed so that the grinding bowl (2) and the drive (4) are thermally decoupled.


A cursory survey on subsolidus equilibria in the system NaAlSiO4-KAlSiO4 was made through sintering of mixtures of chemicals in the proper proportions. The phases were identified by means of the X-ray diffractometer. The results ane shown in Figs. 1 and 2, and Tables 1 and 2. There exists a large miscibility gap between the fields of nepheline and kalsilite. Potassium-rich nepheline stablle at high temperatures should unmix under equilibrium conditions at lower temperatures, giving kalsilite together with more sodic nepheline, as shown in Fig. 3. An unidentified phase "A" is formed at lower temperatures than the orthorhombic form in the region with higher K/Na ratios than kalsilite. The unit cell dimensions of kalsilites were measured as shown in Table 2.


Two cases of calcified thrombus of inferior vena cava in children are reported and the relevant literature reviewed. Although the physiopathology of this lesion is poorly understood and its detection is usually fortuitous, its presentation is univocal.


Directory-based cache coherence protocol is accepted as the common technique in large scale shared memory multiprocessors because of its scalability. Although it was extensively studied in the past, however, the memory overhead and long miss penalty entailed by this protocol are the major obstacles to scale for large scale multiprocessors. On the other hand, the ever-increasing cache line size makes the false sharing problem more serious than before, which will lead to high miss rate. Based on the scope consistency, we propose a lock-specific home-based cache coherence protocol. In this new cache coherence protocol, all directory memory overhead are eleminated completely and false sharing problem and high miss rate will be sloved greatly at the cost of small write notice buffer in each processor.


In this paper, several methods based on signal processing on graphs are proposed to improve the performance of credit card fraud detection. The proposed methods consist of a variant of the classic iterative amplitude adjusted Fourier transform (IAAFT) and two methods that we have called iterative surrogate signals on graph algorithms (ISSG). The objective is to generate surrogate samples from the original scarce fraud samples to improve the training of the detectors by lowering the variance of the estimate. A reliable augmentation of the target scarce population of frauds is important considering issues such as labeling cost; algorithm testing; data confidentiality; and constantly changing of patterns in the data streaming source. We have approached several scenarios with different legitimate and non-legitimate transaction ratios showing the feasibility of improving detection capabilities evaluated by means of receiver operating characteristic (ROC) curves and several key performance indicators (KPI) commonly used in financial business.


Owing to many weaknesses in terms of emergency management existing in the majority of enterprises,so it is highly necessary to systematically analyze and study on emergent management theory in order to speed up emergency mechanism development of enterprises and improve the capabilities and level of emergent management.As viewed from a macro enterprise emergent system,We probed into the feedback mechanisms between the whole and local in some enterprise and constructed causality chart of emergent system to analyze the logic of the system architecture,and set up dynamic simulation model with SD equations.By dint of feedback control theory to conduct calculation and simulation test,we played emphases on effect of safety personnel and emergency facilities on the system,and put forward measures to upgrade the capacity of emergency management.The research also provides references to carrying out theoretical research of emergency management.


High voltage glass insulators are equipment used in power transmission or distribution networks. They consist of a metal bell, a metal pin and a glass or porcelain disk. The joint action of atmospheric pollution, humidity and an intense electric field on the surface of these insulators accelerates the process of corrosion in the metal pin parts, resulting in catastrophic failures in the entire electrical system. In this sense, this case report presents an electrostatic protection device that, aiming to shield the surface of the pins against the pernicious electrical influences, was designed as a screwable Faraday cage made of stainless steel 304 and was denominated "Faraday's ring". To validate the efficacy of the device, electrical field simulations were carried out in 2D models of chains of insulators, which were developed using software that is based on the Finite Element Method, and experimental tests were also carried out with the aid of a Tesla Coil to supply electric discharges on the metallic surface of the device. The simulations and experimental results showed that the device was able to cancel out the intense electric field of ~3 x 103 kV/m in the outer surface and avoid the onset of corrosion within.


Summary. Kessler's goby, a recently introduced fish species in the Budapest region of the river Danube, proved to be infected with two previously undescribed coccidian species. The species having a smaller oocyst (7-8.5 µm) proved to be a Goussia and was named G. kessleri sp. n. The species having larger oocysts measuring 13-14 µm showed characteristics typical of an Eimeria and was designated as E. daviesae sp. n. Oocyst of G. kessleri were spherical, contained four ellipsoidal sporocysts lacking Stieda body. Sporocysts measured 5.8 (5-6) x 3.9 (3.8-4) µm. Oocysts of E. kessleri were spherical, contained four short ellipsoidal sporocysts which tapered at one end and formed at that end a cap-like Stieda body. Sporocysts measured 8 (7.5-8.2) x 4.9 (4.8-5.2) µm. Both species formed oocysts in the intestinal e pithelium. The oocysts of the Goussia were released sporulated, while those of the Eimeria passed in unsporulated or semisporulated condition.


High performance and stable operation are desired features of today's integrated circuits (ICs). Due to its inherent properties, devices based on silicon carbide (SiC) exhibit excellent temperature and radiation tolerance, with performance levels similar to or better than the ones in silicon (Si). Instead of specifically creating circuit topologies suited for SiC, current research efforts are focused on adapting existing Si-based technologies to SiC. In this letter, we report a novel bipolar logic technology designed to exploit the electrical characteristics of 4H-SiC and to outperform conventional technologies. It has fewer transistors, simpler topology, and features simple-to-design complex gates. The circuit shows simulated gate delays as low as 3.3 ns at 27 °C/4.2 ns at 500 °C and noise margins higher than 1 V at 27 °C-500 °C. The proposed technology performs remarkably well across all performance parameters, validating its potential for cost effective, smaller footprint, simple to design, and easily reconfigurable digital ICs in SiC for small-scale logic applications.


Today, landfills can be defined as a facility that was built and equipped for continuous controlled, organized and safe disposal of waste. Solving the problem of waste disposal requires an interdisciplinary team of specialists who will work together to reach an optimal technical solution and a general social acceptance of such a facility. Common Hazardous Management Facility goes through four phases: project definition, preliminary assessment of the impact of site selection, environmental assessment, decision making and implementation. The effects of landfill on the environment can be measurable and immeasurable. Methods for defining these impacts are: net present value method, the method of assessment experts, multicriterial analysis.


It is a new field in error correction of free form lens In this paper, we borrow ideas from digital signal processing, and discuss the method of calculating imputted controlling data The method includes: Basing Fourier Trans form method、Winner filtering method and Direction method Winner filtering method is proved good by emulation with computer At last, several important question in actual work is discussed


The purpose of this study is to explore the goal and the component of Smart learning, analyze the interaction in Smart English education and suggest a Smart learning model based on the results of the analysis. Even though the evolution of Smart learning is expected to improve the English education environment, discussions on Smart learning have just become active in Korea, and the related studies are insufficient. Therefore, it is necessary to analyze Smart learning and interaction in Smart English education. In order to extract implications in implementing Smart learning, an analysis on previous studies about Smart learning was conducted to find the target and components of Smart learning. Also, interactions occurring in Smart learning were analyzed to apply the interactions to Smart English education. These results were applied to a Smart English learning model. The major research findings are as follows: First, thanks to the development of web technology, the individual learning appearing in the learner-content interaction led to the cooperative learning in which learners and teachers interact. Second, Smart learning includes the 21st century skills as a goal, five components as a feature, and activities for interaction with web 2.0 tools.


HELLEMA, M.J.C. (1973): Comparison of bioassays and immunoassays of human chorionic gonadotropin preparations. Europ. J Obstet. Gynec. reprod. Biol., 314, 131-136. A comparison was made of the biological and immunological properties of two commercial HCG preparations and of the fractions obtained after submitting both preparations to gel filtration on Sephadex G-200. The I/B ratio increases from fractions containing high molecular weight material to those with low molecular weight material. The estimates obtained by immunoassays were shown to be dependent on the characteristics of the antisera used. Therefore it was concluded that the reproducibility and comparison of the potency estimates by immunoassays might be improved by standardization of antisera and methods. According to the different properties of the gonadotrophins measured by bioassays and immunoassays, the addition bioassay or immunoassay to IU has to be used. biological activity; immunological activity; human gonadotropin preparations; gel filtration; standardization of antisera