Controlling fowl adenoviral (FAdVs) outbreaks in commercial chicken is of immense importance since such outbreaks of disease can cause economic losses by infecting a large number of broiler chicken. The current study was performed for detection and serotype characterization of FAdVs causing inclusion body hepatitis and hydropericardium syndrome (IBH-HPS) in Pakistani commercial broiler chicken in the year 2015. Tissue samples (liver) of infected birds, manifesting signs of IBH-HPS, were used as source for DNA isolation and detection of FAdVs was done using PCR (polymerase chain reaction) to amplify hexon gene region. Serotype identification and characterization was based on Restriction Fragment Length Polymorphism (RFLP) results, using the restriction enzyme BfoI, together with Sanger dideoxy sequencing. From the cases analyzed, 87% were diagnosed with FAdV 11, therefore marked as the main cause of IBH-HPS, serotype 1 was detected in 10% of cases and least cases were detected of serotype 8 (4%) and serotype 4 (2%). BLAST was used to identify close homologues to the sequenced samples, multiple sequence alignment was performed in MEGA 7.0 Clustal w tool and phylogenetic tree was built to infer relationship between sequenced samples and previous FAdV isolates based on the sequence alignment of partial loop1 region of hexon gene. The sequences of FAdV isolates sequenced in the study were subsequently submitted to NCBI database.


A self-propelled cornstalk or yellow corn silage harvester comprises a corn root stubble cleaning deivce. A header is arranged on a machine frame disposed right ahead a tractor, a stalk crusher is arranged on the upper portion of the machine frame at the back of the tractor, and the stalk crusher is connected with the header through a rake chain conveying device. A tipping bucket type grass box is arranged on the machine frame at the back of the stalk crusher and is connected with the stalk crusher through a discharge blowing drum. The corn root stubble cleaning deivce is arranged on the machine frame below the stalk crusher. The self-propelled cornstalk or yellow corn silage harvester has the corn root stubble cleaning function, can harvest cornstalks with different strain diameters, different planting densities and different heights and of different seasons, and further has the functions of cornstalk harvesting and crushing and corn root stubble cleaning and crushing for returning to the field after harvesting.


Human rights implementation in a multiculturalim world. Human rights goal. How did human rights come into being? Human rights implementation in a multicultural world. Islam and human rights. Origins and fundamental principles of the Islamic culture.


In contrast to the traditional economic theory the paper is to analyze the negative environment externalities in terms of the industrial organization theory and provide the new resolutions.We discuss the negative pollution externalities in the imperfect market structure beyond the perfect market.Based on the traditional perfect market in the neoclassic economics,we show that both Coasian theorem(property right) and Piguian taxation(government intervention) have a great positive effect on the firm production.However,because of the existence of both theories,which is implied by the perfect market,they tell us about the resolution to negative pollution externalities.Once we introduce imperfect market structure,including monopoly,oligopoly,and monopolistic competition,etc,we compare the welfare level under the negative pollution externalities.In principle,by means of market structure,we provide the solutions to the externalities governance,that is,taxation,property right and market structure to resolve the general externalities.They play an important role in China's economic development and sustainability.


Direct marketing such as telemarketing or mailing is an important method for companies to boost their business. Identifying the right proportion of target market could largely cut operational expense and improve efficiency.  In this research, a secondary dataset from a car insurance company will be used to study this problem of market targeting. Basing on existing literature study, three classifiers are picked, Naive Bayesian, Decision Tree, and Neural Network. Some literature researches on each of the algorithm are conducted. Later modelling experiments are performed to predict whether the final customer will purchase the insurance or not.


Based on the study and measure of the cutting force, the empirical formla for cutting force calculating is improved, The results calculated with the improved formula are close to the experiment results.


Bu tez uc bolumden olusmaktadir.Ilk bolum giris kismina ayrilmistir.Ikinci bolumde, Schrodinger dalga denkleminin Jost cozumleri elde edilmistir.Ucuncu bolumde, Jost cozumlerinin varligi ve tekligi arastirilmistir.AbstractThis thesis consists of three chapters.The first chapter is devoted to the introduction.In the second chapter, the Jost solution of Schrodinger wave equation is obtained.In the third chapter, existence and uniqeness of the Jost solution is investigated.


A widely used method to protect steel from corrosion is the cathodic protection by galvanic coupling to a less noble metal (e.g., Zn on Steel) or by applying an external negative potential. Because magnesium is already one of the most reactive technical metals, only the latter approach may be feasible. The question arises if cathodic protection by an external applied potential is a suitable method to protect magnesium alloys from corrosion as, because of the very negative standard potential of Mg, the potential regime of cathodic protection would be situated far from the stability region of water and strong hydrogen evolution will take place. Furthermore, the cathodic polarization provokes the formation of deposition products resulting from the strong alkalization, in theory without the parallel effect of Mg corrosion, so that deposition products could be better qualified regarding their protective properties in electrochemistry. Deposition products are especially expected from the deicing salt additives ...


Micellar-enhanced ultrafiltration(MEUF)is an effective separation technique for removing metal ions from aqueous environment.The simulated wastewater containing nickel ion was treated by MEUF using inorganic ceramic ultrafiltration membrane and sodium lauryl sulfate(SDS),a kind of anionic surfactant.Effects of some important parameters were investigated,such as membrane pore size,concentration of SDS,concentration of nickel ion,pH value of solution.Experimental results indicated that the ultrafiltration effect was the best when temperature was 20 ℃,transmembrane pressure 0.15 MPa,membrane pore size 20 nm and surfactant concentration 6.0 mmol/L.Under the conditions,the rejection ratio of nickel ion was up to 99.25% and membrane flux was 89.65 L/(m2·h).


for their innovative methodological framework. Their research design combines textual analysis of 800 media artefacts (including blog posts, tweets and selfies) and ethnographic methods (including semi-structured interviews with 82 participants; focus groups with 16 girls in a London-based school; and participant observation of online spaces such as Twitter, Facebook and Tumblr). This unique assemblage of research methods allows for a rich analysis of digital activism attuned to the intricacies and nuances of each case study. The remaining five chapters explore different facets of doing anti-rape activism online by focusing on dis-tinct case studies. The authors continuously draw links between each of the case studies through their rigorous analysis, thus highlighting continuities between different digital feminist campaigns, as well online and offline experiences.


Construct and improve the third party logistics system of Guiyang City, it has great significance to the economicdevelopment of Guiyang City, and even Guizhou Province, to construct and improve the third party logistics system of Guiyang City, and to build a modern logistics park in order to give full play to the integration of logistics resources and reduce the function of the social costs of Guiyang City. This article sets out on the development of Guiyang City's macroeconomic policy and microeconomic policy of third-party logistics market, and proposed means of development models about the establishment of third-party logistics park in Guiyang.


Polarimetric Synthetic Aperture Radar data provide a wealth of information. A complete single-frequency observation of this kind is a complex matrix with nine degrees of freedom: three intensities and three complex covariances. There are several ways of extracting valuable information from these observations, among them the use of statistical models. In particular, the difference between the phases of the complex covariances is important in interferometric applications. In this article we survey statistical models for this kind of circular data. We present both physically-derived and empirical distributions, we highlight their relationships and present estimators for their parameters in an unified manner. We present a package for the R platform for statistical analysis of phase data under univariate physical and empirical models, their estimators, and their relationships.


Various tools have been developed to support companies integrating corporate sustainability (CS) into their organisational system. Research on the use of these tools does not clearly show how these tools support the integration process of CS. This paper focuses on the CS integration support of three tools most often mentioned in the literature. We will question the contribution each tool can make in supporting CS integration, based on six integration process elements. The analysis shows a potential complementarity between the tools. Moreover, companies should be critical on where within the organisation the interventions for CS integration are needed and what improvement should be generated before choosing tools.


This research is a quantitative type of correlational research. This study aims to determine the relationship between the ability to read the Al Qur'an with an interest in learning Arabic in grade 8 female students of the Equalization Education of Salafiyah Hidayatul Qomariyah Islamic Boarding School Bengkulu. The entire data obtained was analyzed using descriptive statistical analysis and parametric inferential statistical analysis with the Pearson Product Moment bivariate correlation type. The results showed that the calculation of the relationship between the ability to read the Koran and the interest in learning Arabic in grade 8 female students of the Equalization Education of the Salafiyah Hidayatul Qomariyah Islamic Boarding School Bengkulu had a correlation value (r count) of 0.125 with a very weak interpretation value. Based on the results of this study, it is suggested to Arabic teachers to make methods and media more interesting and intensively motivating female students about the importance of learning Arabic so that there is a high interest in learning Arabic. Keywords: ability to read the Al Qur'an, interest in learning Arabic, Hidayatul Qomariyah


In this paper, the admissibility analysis and controller design issues for a class of nonlinear descriptor systems described by the T–S descriptor fuzzy model with partially unknown membership functions are discussed. New sufficient conditions are first given to ensure the admissibility of such fuzzy descriptor systems. To fully utilise the information of membership functions, the known and unknown parts of membership functions are handled by staircase functions and the bounds of the unknown part, respectively. Different from the traditional parallel distribution compensation (PDC) method, the state-feedback controller design condition is given under an imperfect premise matching method via linear matrix inequalities (LMIs). Some examples are given to show the validity of the proposed methods.


The present invention provides a data updating method, apparatus and eUICC. The data update method is applied to eUICC which the management apparatus and one or more SE arrangement, the one or more SE is configured to store the application corresponding to the one or more profiles (profile). The management apparatus is configured to manage the one or more SE; The data update method wherein the management apparatus receives a profile enabling request, and - the enabling request, the profile is used to target the source profile to switch to the profile, the enable request, the profile is the identifier information of the target profile, and wherein the source profile is a profile in the enabled state, before the switch being; The profile is in accordance with the enabling request, and updates the first correspondence to the second correspondence, the first correspondence relationship between the first set of applications and a corresponding relationship between the source profile, the first application sets the one or more It includes one or more applications in the SE and; The corresponding relationship between the second corresponding relationship is a second set of applications and the target profile, the second set of applications comprises at least one application in the first application sets.


The Computers in Teaching Initiative (CTI) is a programme funded by the Joint Information Systems Committee (JISC) of the Higher Education Funding Councils of the UK with, as its name implies, the purpose of encouraging wider use of computer‐aided methods in university teaching. There are a number of centres which have been set up to disseminate information about the available training packages in specific subject areas. The Centre at Loughborough is concerned with the field of Library and Information Studies (LIS) and is known as CTILIS (Computers in Teaching Initiative Centre for Library and Information Studies).


This analysis was carried out on the title of "Transforming Workers to Winners by Creating the High Performance Organizations".  The main aim of this article was to identify the factors that determine the continuous success of high performance organization. Then to get this objective the paper was organized into introduction, body & conclusion of the reviewed empirical data. Accordingly the empirical data was assessed and finally the conclusions drawn to show directions for business organizations how to make winners their employees.


Subzone Cimanuk sub-watershed upstream is playing an important role towards the conservation of water resources for the downstream subzone. To meet the needs of the community, drinking water for agricultural irrigation. However, the amount of land conversion causes the water system in the watershed disturbed. This study aimed to analyze the changes in land use in the watershed Cimanuk upstream and analyze changes in the carrying capacity of the water system upstream use Cimanuk geographic information systems. The analysis shows that it has increased there use of its land area cultivated by horticultural fields such as carrots, potatoes, and other crops. Food and agricultural land development in research, at least from 2005 to 2015, has an adverse impact on the functioning of the Sub-Basin Upstream Cimanuk characterized by decreasing the carrying capacity for water regulation. Or that the development of agricultural land in this area is actually very appropriate if only from the aspect of that is because of relatively fertile landforms (volcanic areas), but the development has destroyed sub-watershed function itself as a water catchment area.


Additive Manufacturing (AM) method enables to produce products easily, cheaply and quickly with more complex geometry compared to traditional production methods. In this context; Fused Deposition Modeling (FDM) is a widely used for AM method that requires a large number of process parameters. In this study, it is aimed to experimentally investigate the damping capabilities of the metal/polymer composite sleeve bearings printed using FDM. A total of 54 pieces (27 pairs) were printed from composite filaments such as nine pairs for each of PLA, PLA + 20% Bronze, and PLA + 20% Copper metal/polymer with different filling structures (Octogram spiral, Archimedian chords, and 3D Honey comb) and different occupancy rates (10, 30, and 50%), respectively. The experiments were carried out using the shaft-bearing system under the same operating conditions at a rotational speed of 900 revolution per minute (rpm), and vibration data was collected from the rotating shaft with proxy probes. Rotating shaft position is very important to determine journal position in bearing for understanding deterioration in the bearing. Bode and Orbit plots are used to detect the level of deterioration in the bearing. The value of bearing to shaft clearence can vary widely depending on application. Since the bearings were heavily loaded, they were compressed by radial load caused large clearence. The results showed that compressed bearing had significant influence on the stability of rotating shaft system and significant differences in damping capabilities of composite sleeve bearings with different filling structures and occupancy rate. Increasing occupancy rate decreases the vibration amplitude values in copper-reinforced sleeve bearing but increases in bronze-reinforced sleeve bearing. From the microstructure analysis, it has been observed that the vibration absorbation capability is better due to the more homogeneous distribution of the copper reinforced bearings than the bronze reinforced bearings. Also, vibration absorption capability of sleeve bearings with 3D Honeycomb filling structure is increased significantly proportion to the occupancy rate.


Telehealth support can rapidly and significantly increase access to healthcare. For example, during the COVID-19 pandemic, telehealth not only supported patients with COVID symptoms but also improved access to the entire continuum of care, from critical care to mental health services.


The present study was undertaken to evaluate the protective effect of ethanol (EtAS), ethyl acetate (EAAS) and aqueous (AQAS) extracts of Argyreia speciosa (AS) roots against Isoproterenol (ISO)-induced myocardial infarction in rats. The animals were exposed to isoproterenol (200 mg/kg. s.c) twice at an interval of 24 hrs. Cardioprotective effect was assessed by observing ECG parameters, serum marker enzymes and histopathology of the heart. Pretreatment of EAAS, and EtAS (200 mg/kg) resulted in a significant (P


The nonleptonic decays ${\ensuremath{\Lambda}}_{c}^{+}\ensuremath{\rightarrow}{\ensuremath{\Delta}}^{++}{K}^{\ensuremath{-}},{\ensuremath{\Sigma}}^{*0}{\ensuremath{\pi}}^{+}$, and ${\ensuremath{\Xi}}^{*0}{K}^{+}$ and ${\ensuremath{\Omega}}_{c}^{0}\ensuremath{\rightarrow}{\ensuremath{\Xi}}^{0}{\overline{K}}^{0}$, ${\ensuremath{\Omega}}^{\ensuremath{-}}{\ensuremath{\pi}}^{+}$, and ${\ensuremath{\Xi}}^{*0}{\overline{K}}^{0}$ are studied. The dominant contribution for the former decays comes from the $W$ exchange and for the latter decays the $W$ emission gives the dominant contribution. These decays are especially suitable to determine directly the scale of $W$ exchange and $W$ emission from the experimental data. We obtain $\ensuremath{\alpha}({\ensuremath{\Omega}}_{c}^{0}\ensuremath{\rightarrow}{\ensuremath{\Xi}}^{0}{\overline{K}}^{0}\ensuremath{\approx}0.35$.


The recruitment and appointment of principals are one of the most important activities of school and system leaders. The compelling evidence (e.g. Leithwood et al., 2006, 2020) that talented leadership has a signi fi cant impact on school improvement provides empirical support for the proposition that careful preparation and selection of principals are vital if schools and their students are to thrive. The criteria used to appoint principals vary across jurisdictions but typically include teaching experience, instructional leadership knowledge and skills and notions of contextual ' fi t ' . However, such educational considerations may be trumped in some settings by political or administrative imperatives (Xue and Bush, 2021).


A 54-year-old female presented with dysphagia and generalized fatigue. Clinical examination revealed significant radio-radial and radio-femoral delay, right brachial blood pressure 154/90mmHg, and nonrecordable blood pressure in the left brachial artery and lower limb. Barium swallow revealed a smooth indentation over the posterior wall of the esophagus and notching along the inferior borders of the rightsided ribs (Figure 1). Computed tomography angiography showed significant narrowing of the aorta distal to the left common carotid artery origin, involving the left subclavian artery origin (Figure 2), and multiple tortuous collaterals from the right internal mammary artery with large aneurysms causing esophageal compression (Figure 3). The surgical challenges faced were to maintain vital organ perfusion distal to the coarctation, construct leak-proof distal anastomosis of a prosthetic graft just above the diaphragm, bring out the graft from behind the inferior vena cava, between the inferior vena cava and right inferior pulmonary vein, with Figure 1. Barium swallow in (a) anteroposterior and (b) lateral view, showing a smooth impression (black arrow) over the posterior esophageal wall without mucosal irregularity. A well-defined rounded opacity (white arrow) was seen in the right upper lung zone, consistent with a partially calcified aneurysm. Also, notching was seen along the inferior borders of multiple right-sided ribs (dashed arrow).


The transesterification process using heterogeneous catalysts has been widely studied to replace the role of homogeneous catalysts. ZnO doping into metal oxides can increase activity of heterogeneous catalyst in transesterification reaction. This study was conducted to provide information on the effect of ZnO concentration doped into calcium oxide (CaO) to the transesterification reaction of avocado seed oil with high free fatty acid (ALB) to methyl ester, at 65 0 C, methanol ratio: oil = 10: 1 , for 1.5 hours, using a reactor. Research variable is ZnO concentration doped into CaO, that is: 0%, 1%, 2%. The test parameters are methyl ester content obtained from the results of transesterification reaction with gas chromatographi analysis. In this study, ZnO/CaO nanocatalysts were synthesized and doped with sol gel method and calcined at 450 0 C in air for 60 min. The synthesized ZnO/CaO nanoparticles were characterized by XRD. From the experiment, the highest yield of methyl ester was obtained on ZnO/CaO 1% catalyst with yield of 90,8820%.


The implementation of operating system functions can significantly affect the performance of parallel programs. In this paper, we describe our experience with a reconfigurable, multiprocessor threads package on a 32-node KSR1 supercomputer. We discuss static and dynamic configurations that address the on-line reconfiguration of threads schedulers and synchronization constructs. Experimental results are demonstrated with two disparate parallel application programs, (1) a parallel branch-and-bound application and (2) the runtime kernel of a Time Warp discrete event simulator.


Reductionist realist accounts of certain entities, such as the natural numbers and propositions, have been taken to be fatally undermined by what we may call the problem of arbitrary identification . The problem is that there are multiple and equally adequate reductions of the natural numbers to sets (see Benacerraf 1965), as well as of propositions to unstructured or structured entities (see e.g. Bealer 1998 Melia 1992, King, Soames and Speaks 2014). This paper sets out to solve the problem by canvassing what we may call the arbitrary reference strategy . The main claims of such strategy are two. First: we do not know which objects are the referents of proposition and numerical terms since their reference is fixed arbitrarily. Secondly: our ignorance of which object is picked out as the referent does not entail that no object is referred to by the relevant expression. Different articulations of the strategy are assessed, and a new one is defended.


In modern CT imaging, simulation has become an important tool to minimize cost- and time-intensive measurements. It is increasingly used to optimize techniques for complex applications, to support the preparation of written procedures, and for educational purposes. We extended the CT simulation software 'aRTist' with a module to set-up arbitrary trajectories including disturbing influences during the scan. Moreover, such geometric deviations can be compensated by the internal reconstruction tool.


The invention relates to a valve device (12), in particular Abblaseventil- or bypass valve device for an exhaust gas turbocharger (1), comprising a housing (13) and with a valve plate (18) and valve stem (15) having valve element (16), wherein the valve stem (15 ) is axially displaceably supported in a valve guide (14) of the housing (13), and (at its valve disc 18), the opposite end with a flexible membrane (25) is connected, which (together with housing 13) a pressure chamber (26) forms for actuating the valve means (12), wherein the pressure chamber (26) has a compressed air connection (28), and wherein the valve disc (18) in the unactuated state spring-biased is urged against a valve seat (19) to block a flow channel (11) , It is contemplated that the housing has one of the flow channel (11) independent air outlet (34) through which the compressed air from the pressure chamber (26) and gaseous medium from the flow channel (11) enters the valve guide from the valve means (12) to escape.


Background: To compare the impact of full-face (FFM) and nasal masks (NM) for guaranteeing nocturnal high-intensity non-invasive positive pressure ventilation (Hi-NPPV) with focus on gas exchange and sleep quality in chronic hypercapnic COPD. Methods: In a randomized cross-over trial 30 COPD patients (mean age 64,9±8,78, mean FEV1 33,47±12,91 ) with well-established HI-NNPV were measured for two consecutive nights using full polysomnography, transcutaneous PCO2 monitoring and subjective assessments. FFM and NM were randomly assigned while ventilator settings remained unchanged. All patients were using Hi-NPPV at home for at least one month, prior to inclusion. Primary outcome was sleep efficiency. Results: Mean ventilator settings were as follows: IPAP 26±3 cmH2O, EPAP 5±1 cmH2O, respiratory rate 17±1 /min) There was a clear trend for a better sleep efficiency (primary outcome) when using a FFM (60.4±19.6 % vs. 50.5±24.9 %, P=0.054). Sleep stages 3/4 were in favor of FFM (34.2%±21.4 % vs. 22.9%±18.6 %, P=0.03). Mean transcutaneous PCO2 was comparable: 48.9±6.6 mmHg (NM) vs. 47.7±7.4 mmHg (FFM), P=0.3). Subjective evaluation of patients' satisfaction showed no clear trend for favoring NM or FFM, respectively, even though leakage was subjectively less when using a NM. Conclusion: Both NM and FFM are capable of successfully delivering HI-NNPV. FFM, however, is superior over NM concerning sleep quality, but this would need to be balanced against subjective leak occurrence. Method: COPD; Non-invasive Ventilation, HI-NPPV, respiratory insufficiency, hypercapnia


This volume contains eleven chapters which deal with various growing points in haematology. The topics chosen range as widely as from instrumentation and automation in haematology (Dr G. Brittin and Dr G. Brecher) to food iron absorption (Dr M. Layrisse and Dr C. Martinez-Torres), and from the plasma kallikrein-kinin system (Dr R. W. Colman, Dr G. J. D. Girey, Dr R. Zacest and Dr R. C. Talamo) to red cell metabolites, haemoglobin and the oxygen dissociation curve (Dr F. A. Oski and Dr A. J. Gottlieb). In general, the present volume maintains the high standard of its predecessors. An outstanding chapter, written by Dr J. M. White and Professor J. V. Dacie, reviews the clinical and molecular features of the unstable haemoglobins. Some idea of the rapid advances that are now taking place in this, as in other areas of haematology, however, is illustrated by the fact that at least twenty new unstable haemoglobins have been recognized since this review of the first thirty such haemoglobins to be documented was completed. The longest chapters are comprehensive and exhaustively referenced reviews of the leukaemias by Dr D. A. G. Galton and Dr A. S. D. Spiers and of platelet function in health and disease by Dr J. Hirsh and Dr J. C. G. Doery; the shortest and, in some instances, easier to read, concern disorders of phagocytic cell function (Dr D. G. Nathan and Dr R. L. Boehner), surface cell receptors (Dr S. Kornfeld and Dr R. Kornfeld) and the haemopoietic action of androstanes (Dr L. Sanchez-Medal). An interesting chapter on erythrocytes in blood rheology (Dr P. L. LaCelle and Dr R. I. Weed) completes the volume. This book is probably too expensive for many individuals to buy their own copy. Nevertheless, it provides a relatively painless way of learning about many of the recent advances in haematology and it is to be hoped, therefore, that it will be widely read.


The esterification of benzoic acid and isobutyl alcohol was studied using nanometer titanium oxide as heterogeneous catalyst and the excess isobutyl alcohol as azeotropic water stripping agents.The effects of different factors such as mole ratio of reactants,reaction time and catalyst dosage on the yield of isobutyl benzoate were carefully investigated.The experimental results showed that nanometer titanium oxide exhibited excellently catalytic activity.The best reaction conditions were as follows:the amount of benzoic acid was 0.1mol,mole ratio of isobutyl alcohol to benzoic acid was 3.0∶1,the dosage of catalyst was 1.2% of the total mass of the reactants,refluent reaction time was 2.0h.Under this condition,the esterification yield was 98.7%.The catalyst could be repeatedly used six times without loss catalytic.


A new detecting method for apples' early defects which was based on the image fusion of infrared and visible images was introduced in order to distinguish and separate the fruits with mechanical damage. Using apple as the research object, the basic detecting process was expounded, and the process of image registration was introduced emphatically. An improved algorithm of image fusion, which was based on wavelet transform, was proposed. Then the experimental result was provided as well as the objective evaluation for it.


Diabetes mellitus (DM) is a chronic metabolic disorder and one of the most challenging health problems worldwide. Left untreated, it may progress causing serious complications. Genetics, epigenetics, and environmental factors are known to play an overlapping role in the pathogenesis of DM. Growing evidence suggests the hypothesis that the environment induces changes in the early phases of growth and development, influencing health and disease in the adulthood through the alteration in genetic expression of an individual, at least in part. DNA methylation, histone modifications and miRNAs are three mechanisms responsible for epigenetic alterations. The daily diet contains a number of secondary metabolites, with polyphenols being highest in abundance, which contribute to overall health and may prevent or delay the onset of many chronic diseases. Polyphenols have the ability to alter metabolic and signaling pathways at various levels, such as gene expression, epigenetic regulation, protein expression and enzyme activity. The potential efficacy of polyphenolic compounds on glucose homeostasis has been evidenced from in vitro, in vivo and clinical studies. The present review is designed to focus on epigenetic regulation exerted by polyphenolic compounds in DM and their complications, as well as to summarize clinical trials involving polyphenols in DM.


The community palliative care team based at Florence Nightingale Hospice comprises clinical nurse specialists (CNSs) covering a patient population of 200,000. The team has provided a 7-day, nine-to-five service, for 6 years. Recent changes to Buckinghamshire's general practitioner out-of-hours' service, and the government's improved access agenda and legislation, has permitted non-medical prescribing. This has resulted in the team embracing the prescribing role. Since …


Ambient intelligence requires that devices integrated to the environment are self-sustaining and maintenance free. To fulfill the vision of ambient intelligence, the design of small wireless embedded systems powered by energy harvesting is needed. Our work raises awareness that generic embedded system and wireless sensor nodes are different from wireless embedded systems powered by energy harvesting (WESPEH) therefore a different design approach is required. The work introduces a new design technique based on rapid prototyping and constraints analysis. From different groups of constraints the software problematic is developed in detail further with the focus on operating system design. Comprehensive analysis of thin resource operating systems leads to the conclusion that existing systems are not designated to run on a dedicated WESPEH hardware platform. We define the requirements, architecture and design aspects of energy autonomous operating systems. Based on these definitions a new operating system DolphinAPI is designed and implemented. The initial implementation is performed on the EO3000I hardware platform. Analysis of existing benchmark methods shows that common benchmark methods focus entirely on the computational performance, neglecting other important features of an operating system such as memory needs or influence on the energy consumption. Therefore a new operating system quantification methodology considering energy consumption, scheduler behavior and application utiliza∗Recommended by thesis supervisor: Assoc. Prof. Tibor Krajčovič. Defended at Faculty of Informatics and Information Technologies, Slovak University of Technology in Bratislava on November 24, 2011. c ⃝ Copyright 2012. All rights reserved. Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies show this notice on the first page or initial screen of a display along with the full citation. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, to republish, to post on servers, to redistribute to lists, or to use any component of this work in other works requires prior specific permission and/or a fee. Permissions may be requested from STU Press, Vazovova 5, 811 07 Bratislava, Slovakia. Strba, A. Wireless Embedded Systems Powered by Energy Harvesting. Information Sciences and Technologies Bulletin of the ACM Slovakia, Vol. 4, No. 1 (2012) 1-13 tion is introduced . The methodology is based on vector definition and trace-driven performance analysis. Using the methodology TinyOS and Dolphin API is evaluated and compared. For an objective evaluation TinyOS is migrated to the EO3000I hardware platform. As part of the migration the EnOcean protocol stack is implemented in NesC.


"For readers interested in Red Power, Brown Power, women's liberation, peace movements, queer politics, and the white left, this important volume offers new perspectives and information that is not available elsewhere. The essays, by a mix of emerging scholars and scholar-activists, offer views of the recent past that should reshape the consensus about the 1970s to focus on activism, organizing, and violence from above and below." -Felicia Kornbluh, author of The Battle for Welfare Rights: Politics and Poverty in Modern America "Important and insightful, The Hidden 1970s boldly reimagines a decade that remains understudied and misunderstood." -Peniel E. Joseph, author of Waiting 'Til the Midnight Hour: A Narrative History of Black Power in America The 1970s were a complex, multilayered, and critical part of a long era of profound societal change. Indeed, several iconic events of "the sixties" occurred in the ten years that followed. The Hidden 1970s explores the distinctiveness of those years, a time when radicals tried to change the world as the world changed around them. This powerful collection is a compelling assessment of a wide variety of left-wing social movements during the period that many have described as dominated by conservatism or confusion. Contributors examine critical and largely buried legacies of the 1970s. Their essays provide fascinating insight into the myriad ways that radical social movements shaped American political culture in the 1970s and how they continue to do so today. Dan Berger is the author of Outlaws of America: The Weather Underground and the Politics of Solidarity and the coeditor of Letters from Young Activists.


Modern views on the role of c-AMP and c-CMP in the regulation of metabolism and function of the neuron and synaptic transmission are presented. A hypothesis is put forward of the participation of these cyclic nucleotides in the control of epileptogenic focus through modulation of the resting potential of the neuron.


Headache happens in the majority of patients with Cerebral Venous Thrombosis (CVT) being sometimes the sole manifestation of the disease. Herein we report a case‐series of CVT, focusing on headache characteristics.


Diterima : 28/08/2019 Disetujui : 30/10/2019 Abstract Termite family Termitidae is a type of wood-eating termites, humus, or materials consisting of cellulose. This familia termite has a role in helping the ecosystem as a decomposer by destroying wood or other organic material and returning it as nutrients to the soil. Preference or prefer food sources that exist in the environment, influential in supporting the development of termites. The purpose of this study is to find out the type of wood that is a food preference for termites and species of the termite family Termitidae in the Bantarbolang Pemalang Nature Reserve in Central Java. This research was conducted at the Bantarbolang Nature Reserve located in the Kebon Gede Village Area, Bantarbolang District, Pemalang Regency, Central Java. The research method used survey method with termite sampling technique on the milestone paying attention to the depth of entering the forest (0 m, 50 m, 100 m, 150 m and 200 m) from the edge of the forest and paying attention to the age of the post since cutting trees. Termite species were taken on teak (Tectona grandis), Wangkal (Albizia procera), and Mahoni (Switenia marcrophilla) stakes found in areas of 0 m to 200 m. The data obtained were analyzed using analysis of variance (ANOVA). The termites taken are inserted into vial bottles containing 70% alcohol and all termite colonies are counted to determine the number of individual termites. Measurement of environmental parameters include temperature, humidity, soil pH, canopy cover and light intensity. The results obtained by a species of termite Macrotermes gilvus familia Termitidae. The results of data analysis using the f test on teak (T. grandis), Wangkal (A. procera), and Mahoni (S. marcrophilla) milestones show that P > 0.05, which means the age of the milestone and the distance of the milestone from the forest edge do not affect significantly to the presence of Macrotermes gilvus termites on these wooden posts. The conclusion of this study is that the preferences of Macrotermes gilvus termites for various wooden stakes in the Bantarbolang Nature Reserve are not influenced by the age of the stakes and the distance of the wooden stakes from the edge of the forest.


Hypothesis / aims of study Overactive bladder (OAB), is defined by the International Continence Society as urgency, with or without incontinence, usually accompanied by frequency and nocturia, in the absence of obvious bladder pathology. Previous studies have suggested that neurotoxins such as resiniferatoxin (RTX) and onabotulinum toxin A (OnabotA) can be used in patients refractory to oral anticholinergics. Therefore, we prospectively compared the efficacy of a single bladder instillation of resiniferatoxin, 100 nM, versus a bladder wall injection of 100 U of OnabotA in the treatment of OAB symptoms. Our primary objective was the reduction in the number of incontinence episodes; secondary objectives were the effect in urinary frequency, cystometric capacity, evaluation of post void residual urine, and OAB quality of life score (OABq).


The possibilities of synchronizing lambing and increasing reproduction by using exogenous hormones in Karakafl ewes raised under rural farm conditions and growth characteristics of their lambs were investigated. 112 Karakafl ewes at 2-5 ages were randomly assigned into treatment (n = 45) and control (n = 67) groups during breeding season. The ewes in treatment group were placed with 60 mg Medroxyprogesterone acetate (MPA) containing intravaginal passaries for 14 days and received 600 IU PMSG injections at passary withdrawal. Ewes in the control group were not treated and allowed to mate at their natural estrus. Ram introduction for both groups was performed in pasture in village common flock in free mating system. Litter size and twinning rates for treatment and control groups were 1.06 and 1.04; and 6.45 and 4.08 %, respectively, for the first two cycles related to passary withdrawal (P > 0.05). When the expected lambing time was considered, the proportions of the lambed ewes in the first 7 and 10 days were 70.97% and 70.97% for treatment, and 20.41% and 26.53% for control group. The differences in lambing rates in both periods between groups were significant (P < 0.05). Birth weight, 1st, 2nd, 3rd and 4th month live weights, weaning weight and daily live weight gain in treatment group lambs were 3.63 - 0.13, 9.30 - 0.41, 16.54 - 0.50, 23.62 - 0.77, 31.97 - 0.66, 31.57 - 0.92 and 0.221 - 0.008 kg; and, in control group lambs were 3.26 - 0.12, 10.11 - 0.44, 17.80 - 0.53, 26.30 - 0.82, 34.59 - 0.75, 34.42 - 0.96 and 0.244 - 0.008 kg, respectively. Except birth weight, treatment group lambs' live weights in all periods were lower than control ones (P < 0.05 and P < 0.01). The results of this study indicate that in order to run studies to control reproduction by using exogenous hormones in rural conditions successfully some precautions and technical support are


A hierarchy distributed route structure based on IPv6 address in peer to peer systems is proposed in order to solve the problems that physical topology and logical network do not match so as to inefficient search in distributed hash table at present.By building node identifier using IPv6 address and hashing different level clustering identifier to set up hierarchy route,near nodes in physical network are closer in overlay.Lower search latency and higher efficiency are proved.Meanwhile,multi-key-words is hashed to hierarchy key identifier according to the weights so that the similar documents are gathered at adjacent nodes.Multi-


This report contains a comparison of the results from tests on two configurations of a v/STOL aeroplane model at Mach numbers between 0.6 and 1.2 in +he NLR subsonic transonic pressure wind tunnel at Amsterdam and the NASA 8-foot transonio pressure tunnel at langley Field. The correlation between the results obtained in the two tunnels is quite satisfactory.


Background: Undernourishment is a major public health challenge worldwide, with severe economic consequences. If occurs in the first years of life, it may cause long-lasting effect, particularly regarding personal development and economic growth of the country. Objectives: The current study aimed to investigate the influence of socioeconomic factors, particularly education and national income, on undernourishment in selected countries of South Asia. Methods: The annual panel data for 2001 to 2018 were analyzed using the vector error correction model (VECM) technique and the Toda-Yamamoto Granger causality test (TYGCT). Results: According to the results of the VECM, adult literacy has mixed effects on undernourishment in the short run, while in the long term, it is associated with significant improvements in undernourishment. There is a negative association between economic growth and undernourishment in the short term; while, it disappears in the long term. The TYGCT is designed to validate the findings of the VECM as well as to investigate their robustness. According to the findings of the TYGCT, adult literacy alone can both improve undernourishment and enhance economic growth. Conclusions: This study demonstrated a negative association between undernourishment and adult literacy rate in the long term; that is, higher literacy is associated with lower rates of undernourishment, which in turn results in improved community health. Adult literacy causes declined undernourishment and enhanced economic growth. Therefore, South Asian countries should incorporate appropriate interventions based on health and nutritional evidence in the curricula of schools to, firstly, gear up the nutritional awareness and, secondly, to strive redistribution of income among the relatively poor, which may reduce the undernourishment to a significant extent.


Runaway behaviors among teenagers have been studied for some 40 years. Still, because runaway and homeless youths have often been confounded, little is known about what really defines a runaway adolescent. This study targets three objectives in a mixed-method design relying on data from official files and interviews: the descriptions of teenagers reported as missing (e.g., age, sex, runaway duration and reiteration, place left behind, type of caller reporting the child as missing, motivation for closing the file) and the understanding of runaway pathways and dynamics. These studies can contribute to prevention and intervention programs by providing new perspectives on how runaway experiences should be understood in light of the adolescent process.


<abstract>
$ S $-$ SDDS $-$ B $ matrices is a subclass of $ P $-matrices which contains $ B $-matrices. New error bound of the linear complementarity problem for $ S $-$ SDDS $-$ B $ matrices is presented, which improves the corresponding result in [<xref ref-type="bibr" rid="b1">1</xref>]. Numerical examples are given to verify the corresponding results.
</abstract>


In spite of extensive efforts to control diabetes with the help of healthy meals, exercise, and medications, the prevalence of diabetes is on the rise. One factor contributing to this problem is unhealthy cultural habits being practiced in different cultures. This paper lists some of the major cultural habits that need to be changed towards mitigating the global problem of diabetes and other chronic diseases.


Abstract. We develop a two-dimensional enhanced hyperchaotic Henon map (2D-EHHM) to overcome the problems of small chaotic range and poor security when the 2-D traditional Henon map is implemented in cryptosystems. The performance evaluations show that the 2D-EHHM has wider chaotic range, higher chaotic complexity, better ergodicity, and hyperchaotic behavior compared with certain existing chaotic maps. Based on the 2D-EHHM, we further design an efficient image encryption algorithm consisting of a multiple block substitution stage (MBSS) and a bidirectional-dynamic diffusion stage (BDDS). In the MBSS, a plain image is divided into several nonoverlapping multiple blocks to carry out permutation operation. In the BDDS, the scrambled image is redivided into nonoverlapping sub-blocks of the same size to be diffused dynamically in the forward and backward directions. Moreover, the SHA 512 function is employed to obtain a 512-bit plain image hash value treated as a raw key. A variable-length secret key (at least 128 bits), which is dynamically selected from the raw key and regarded as a valid key, is utilized to generate the initial values for the chaotic system. Simulation results and security analysis show that the proposed algorithm can resist various cryptanalytic attacks and can be applied to real-time data transmission.


The erosion-induced loess landslide is a typical landslide in the Loess Plateau.It has important practical significance to do some research on its mechanism.Taking Anli landslide in Yaozhou district,Shaanxi province as example,this paper discusses its initiation mechanism,establishes finite element models at different stage caused by headward erosion before sliding through finite element method,and calculates the stress and strain fields in each stage.On this basis,the shear stress,normal stress and shear strength on the final sliding surface in every model are obtained.The stability factors are also acquired by limit equilibrium method.The result shows that,with the deepening headword erosion,the shear stress on sliding surface increases constantly;but the shear strength decreases conversely.The stability of the whole landslide never reduced until failure.The experimental result shows that,the low-strain can produce a significant excess pore water pressure in saturated loess.Therefore,the excess pore water pressure in saturated sliding zone fosters the failure of this landslide.Comparing the shear stress and the shear strength,the erosion-induced landslide has a failure from the foot to the back part gradually.Therefore,this kind of landslides has characteristics of traction damage.


Along with various other strands in contemporary cultural studies, postcolonial commentary has done much to shift attention away from unitary readings of texts, particularly by placing as much emphasis on the where as on the when and the how of writing and other cultural formations. That where has a good deal to do with the locations – personal, commercial, linguistic and geographical among them – of a text's production, but it also involves the complex of factors that come into play in the reading of texts, which invariably generates new meanings, even on the part of "innocent" readers, who willy-nilly find themselves engaging in acts of interpretation, as they read across places, periods, regions and languages, all of which are themselves in flux. Books are, of course, notoriously unstable objects, given to reinventing themselves when read in fresh contexts. Jane Eyre and Robinson Crusoe undergo transformations, when one returns to them after reading Rhys's Wide Sargasso Sea and Coetzee's Foe. Mansfield Park becomes less comfortable, once the purpose for Sir Thomas Bertram's absence from the security of the country house – to deal with problems on the family's slave plantation in Antigua – is foregrounded.1 But, even when there are no such obvious transnational trajectories compelling reassessment, reading contexts invariably modify readers' views of the meanings of texts, as they become participants in the production of their meanings. As Karin Littau puts it, "The reader is akin to a writer, because he or she is not the passive consumer of a finished product, but – very literally – a collaborator in the process of text production and therefore also an active producer of meanings";2 and the situations, physical and mental, in which readers experience texts influence the ways in which they construct fictional places. Two examples of reading locations influencing readers' responses taken from the pages of canonical novels help to illustrate this. The first is again from Jane Austen and again involves the way in which a country house is imagined. In Northanger Abbey, Catherine Morland comes across a range of written ephemera (a linen inventory, a farrier's bill, etc), on a dark and stormy night at the Abbey, under the spell of having read Anne Radcliffe's The Mysteries of Udolpho and believes she has chanced upon a mysterious Gothic manuscript, only to find her colourful imagination has romanticized the mundane and what she has learnt about "human


In this paper, we present the MPEG-1 Audio bitstreams processing work which our research group is involved in. This work is primarily based on the processing of the encoded bitstream, and the extraction of useful audio features for the purposes of analysis and browsing. In order to prepare for the discussion of these features, the MPEG-1 audio bitstream format is first described. The Application Interface Protocol (API) which we have been developing in C++ is then introduced, before completing


This study investigated perceived transformational leadership and core self evaluations as predictors of safety compliance among health workers. Two hundred and fifty (250) health workers comprising one hundred and forty (140) males and one hundred and ten (110) females participated in this study. Participants were randomly selected from two government owned hospitals in Enugu State. Their ages ranged from 20 to 67 years with a mean age of (M = 36.70, SD = 7.91). The study was cross sectional in which core self evaluation scale, transformational leadership sub-scale of the adapted multifactor leadership questionnaire and compliance with safety behavior scale were administered for data collection. Hierarchical multiple regression was used for data analysis. The results indicated that transformational leadership was a significant positive predictor of safety compliance while core self evaluations was also a significant positive predictor of safety compliance among health workers. The implication and recommendations were further discussed.


Cyanobacteria are promising microbial hosts for production of various industrially relevant compounds, such as succinate, a central metabolite of the tricarboxylic acid cycle (TCA). Cyanobacteria have been engineered to produce succinate during photoautotrophic growth, and are also able to secrete it during anoxic fermentation conditions. It has been assumed that under anoxic darkness, succinate can be formed by reduction of fumarate catalyzed by the succinate dehydrogenase complex (SDH), however, no characterization of SDH regarding this activity has been performed. In this study, we address this issue by generating strains of the unicellular cyanobacterium Synechocystis PCC 6803 (Synechocystis) deficient in one or several subunits of SDH, and investigating succinate accumulation in these strains during dark anaerobic fermentation. The results showed higher succinate accumulation in SDH deletion strains than in the wild type, indicating a succinate dehydrogenase activity of SDH rather than fumarate reduction under these conditions. We further explored the possibility of another potential route for succinate formation from fumarate via L-aspartate oxidase (Laspo). The gene encoding Laspo in Synechocystis could not be inactivated, indicating an essential function for this enzyme. Using purified SynLaspo, we could demonstrate in vitro that in addition to L-aspartate oxidation the enzyme exhibits an L-aspartate-fumarate oxidoreductase activity. We therefore suggest that reduction of fumarate to succinate during anoxic darkness can be a byproduct of the Laspo reaction, which is the first step in biosynthesis of NAD cofactors. This work contributes to the understanding of cyanobacterial TCA cycle for future engineering and sustainable production of dicarboxylic acids.


Current evidence suggests the benefit of a diet containing anaplerotic odd‐chain medium chain fatty acid (MCFAs) for cardiac symptoms in patients with long chain fatty acid oxidation defects (Roe & coll. JCI, 110(2):259‐69, 2002), although the underlying mechanism remains unclear. We conducted a study to evaluate the anaplerotic status of VLCAD−/− mouse hearts, using our working mouse heart model and 13C‐methodology. Furthermore, the expression of selected anaplerotic genes (using real time PCR), and the myocardial levels of CAC intermediates were assessed in fed and 24h fasted mice. Compared to controls VLCAD+/+, 3 month‐old VLCAD−/− hearts showed a 40% lower anaplertoic flux through pyruvate carboxylation (p<0.05). Furthermore, VLCAD−/− hearts displayed lower mRNA levels for enzymes involved in anaplerosis, namely pyruvate and propionyl‐CoA carboxylase, but not malic enzyme, when compared to their normal counterparts, changes that were however age‐ and condition‐dependent. Besides, two‐way Anova revealed a species effect on CAC intermediates levels, specifically succinate and malate, which were lower in VLCAD−/− hearts from 7 month‐old mice. Collectively, our data highlight, impaired anaplerosis in VLCAD−/− mouse hearts, suggesting a potential beneficial role for odd‐chain MCFAs. (Supported by NIH & CIHR)


We review a construction called Non-Perturbative Gauge-Higgs Unification which is a rather rare type of Higgs mechanism that is a pure quantum and bosonic effect. It is constructed on a five-dimensional "orbifold lattice" with SU(2) bulk gauge symmetry and a (spontaneously broken) Abelian-Higgs like theory on the boundaries.


The kimberlite fields scattered across the NE part of the Siberian Craton have been used to map the subcontinental lithospheric mantle (SCLM), as it existed during Devonian to Late Jurassic time, along a 1000-km traverse NE‐SW across the Archean Magan and Anabar provinces and into the Proterozoic Olenek Province. 4100 garnets and 260 chromites from 65 kimberlites have been analysed by electron probe (major elements) and proton microprobe (trace elements). These data, and radiometric ages on the kimberlites, have been used to estimate the position of the local (paleo)geotherm and the thickness of the lithosphere, and to map the detailed distribution of specific rock types and mantle processes in space and time. A low geotherm, corresponding approximately to the 35 mW=m 2 conductive model of Pollack and Chapman [Tectonophysics 38, 279‐296, 1977], characterised the Devonian lithosphere beneath the Magan and Anabar crustal provinces. The Devonian geotherm beneath the northern part of the area was higher, rising to near a 40 mW=m 2 conductive model. Areas intruded by Mesozoic kimberlites are generally characterised by this higher, but still 'cratonic' geotherm. Lithosphere thickness at the time of kimberlite intrusion varied from ca. 190 to ca. 240 km beneath the Archean Magan and Anabar provinces, but was less (150‐180 km) beneath the Proterozoic Olenek Province already in Devonian time. Thinner Devonian lithosphere (140 km) in parts of this area may be related to Riphean rifting. Near the northern end of the traverse, differences in geotherm, lithosphere thickness and composition between the Devonian Toluopka area and the nearby Mesozoic kimberlite fields suggest thinning of the lithosphere by ca. 50‐60 km, related to Devonian rifting and Triassic magmatism. A major conclusion of this study is that the crustal terrane boundaries defined by geological mapping and geophysical data (extended from outcrops in the Anabar Shield) represent major lithospheric sutures, which continue through the upper mantle and juxtapose lithospheric domains that differ significantly in composition and rock-type distribution between 100 and 250 km depth. The presence of significant proportions of harzburgitic and depleted lherzolitic garnets beneath the Magan and Anabar provinces is concordant with their Archean surface geology. The lack of harzburgitic garnets, and the chemistry of the lherzolitic garnets, beneath most of the other fields are consistent with the Proterozoic surface rocks. Mantle sections for different terranes within the Archean portion of the craton show pronounced differences in bulk composition, rock-type distribution, metasomatic overprint and lithospheric thickness. These obser


A single longitudinal mode parametric oscillator scanning over a range of at least 5 cm-1 is described. The linewidth is less than 300 Mhz. Single mode operation during the scan is maintained by locking the OPO output spectrum to an etalon. This scheme and some experimental results are presented.


The metaphysical naturalism underlying most of contemporary scientific and philosophical discourse stands in need of reformation because it leaves out of account one of the most salient features of the world-the normativity that lies at the heart of life itself, and of all higher human forms of value and striving. In the introduction, "Why Naturalism Needs a Reformation," I agree with Alvin Plantinga that


Background: It is known that a short period of cardiopulmonary resuscitation (CPR) prior to defibrillation improves survival in patients with unwitnessed sudden collapse. However, there has been no report about whether CPR restores myocardial ATP during prolonged ventricular fibrillation (VF). The aim of this study is to investigate the effect of CPR on restoration of myocardial high energy phosphate in prolonged VF. Methods and Results: Seventy two adult male Sprague-Dawley rats (330–400 g) were enrolled in the study. Baseline ATP and ADP prior to induction of VF were measured from 9 animals. Sixty three animals were subjected to 4 minutes of untreated VF. Then, animals were randomized into no-CPR group (n=37) and CPR group (n=26). In no-CPR group, ATPs and ADPs were measured 4 (n=9), 6 (n=10), 8 (n=8), and 10 (n=10) minutes after induction of VF, respectively. CPR group received 2 (n=10), 4 (n=8), and 6 (n=8) minutes of mechanical chest compressions, respectively. Baseline myocardial ATP (nmol/mg pr...


Potentials of mean force (PMF) are calculated for two model ion pairs in two non-aqueous solvents. Standard non-polarizable molecular dynamics simulation (NPMD) and approximate polarizable simulation (PMD) are implemented and compared as tools for monitoring PMF profiles. For the polar solvent (dimethylsulfoxide, DMSO) the PMF generated in terms of the NPMD reproduces fairly well the refined PMD–PMF profile. For the non-polar solvent (benzene) the conventional NPMD computation proves to be deficient. The validity of the correction found in terms of the approximate PMD approach is verified by its comparison with the result of the explicit PMD computation in benzene. The shapes of the PMF profiles in DMSO and in benzene are quite different. In DMSO, owing to dielectric screening, the PMF presents a flat plot with a shallow minimum positioned in the vicinity of the van der Waals contact of the ion pair. For the benzene case, the observed minimum proves to be unexpectedly deep, which manifests the formation of a tightly-binded contact ion pair. This remarkable effect arises owing to the strong electrostatic interaction that is incompletely screened by a non-polar medium. The PMFs for the binary benzene/DMSO mixtures display intermediate behaviour depending on the DMSO content.


Objective To study the result of the clinical application of the modified close-mouth impression method in severely resorbed edentulous mandible patients,looking for a impression method to have a stronger force to stabilize the complete denture for the non-surgical patients with low-alveolar.Methods 40 cases of severely resorbed mandibular edentulous patients were divided into two groups.The complete denture of one group was made by the modified close-mouth impression method and the other by the traditional open-mouth impression method.Made a satisfaction survey at 1 week,2 weeks,1 month and 3 month after wearing the complete denture and made statistical analysis of the result by SPSS10.0 statistical software.Results The complete denture made by the modified close-mouth impression method was better than the complete denture made by the traditional open-mouth impression method in the language,chaw,stabilization and comfortable and had a statistical difference.Conclusion the modified close-mouth impression method can be used generally for the severely resorbed mandibular edentulous patients in making the complete denture,it is more suitable for the functional status oral environment,and improved the stabilization at functional status,reduced the times for repairing the denture,and the medical technology is simple and easy to grasp.


This paper provides a systematic framework for the analysis and improvement of nearmiss programs in the Chemical Process Industries. Near-miss programs improve corporate Environmental, Health and Safety (EHS) performance through the identification and utilization of accident precursors. By remedying precursors that signal the potential for an accident, accident rates may be reduced. Effective near-miss programs encourage employee involvement in all stages of near-miss management. Based on over one hundred interviews at twenty chemical and pharmaceutical facilities, a seven-stage framework has been developed and is presented herein. The framework enables sites to analyze their own near-miss programs, identify weak management links, and implement improvements.


Objective To analyze and study the correlation between the ankle-brachial index and the incidence of diabetic nephropathy.Methods 200 patients with diabetes treated in our department from August 2009 to August 2011 were selected.After urinary microalbumin excretion,100 patients were assigned to the diabetic nephropathy group (observation group).The other 100 patients were diabetic-non-nephropathy group (control group).The two groups of patients were comparable in terms of gender,age,course of disease and other aspects.The 24-hour urinary protein determination,urine mALB,renal function,blood potassium,blood glucose,blood pressure and ABI were measured,and the correlation between ABI and diabetic nephropathy was analyzed statistically.Results The observation group and the control group were significantly different in the 24-hour urinary protein determination,urine mALB,systolic blood pressure,diastolic blood pressure and blood potassium.ABI and 24-hour urinary protein determination showed linear correlation,with the Pearson correlation coefficient r=-0.99.Conclusion Through this experiment,the correlation between it and the ABI was testified.ABI combined with 24-hour urinary protein determination can serve as the assessment indicators of whether diabetes is complicated by nephropathy.


The purpose of this study was to identify ideas about how occupational safety and health (OSH) professionals influence decision-makers on matters impacting occupational health and safety management systems. A modified nominal group technique was used that involved 67 participants in ten nominal groups and identified the most important ideas about how OSH professionals can influence workplace safety and health decision making. The research produced themes of communication, scientific, professionalism, leadership, adaptability, and business acumen that resulted in six domains of occupational safety and health professional influence.


We have studied coherent interactions of zero-π (0-π) pulses with a two-level system. The complete undamped Bloch equations and their rotating-wave, slowly varying envelope approximation version have both been considered. An expression describing a pulse Bloch–Siegert shift has been found. We also show that, within the usual Bloch theory, nonresonant 0-π pulses may lead to complete inversion of the atom.


Objective  The number of hours worked by specialty trainees has come under scrutiny recently. One approach aimed at decreasing the number of consecutive hours worked is the night shift call system (NSCS). This study aimed to determine the advantages and disadvantages of an NSCS compared with those of the conventional overnight call system (ONCS).


Based on the practical characteristics of large span and duplex arch of Xipuling tunnel,this paper expounds the workings of regression analysis and the analytical method of monitoring and surveying data in the construction of tunnels.Analyses are made on the problems in the construction of Xipuling tunnel and relevant measures are presented.Through monitoring and surveying of surrounding rocks in the construction,the deformation and stress developments of surrounding rocks and supporting structures are timely in possession,thus ensuring the successful construction of the tunnel.


Introduction: The KLE98300 meteorite is an Antarctic meteorite and is classified as an EH3 chondrite [1]. In this meteorite, we found large numbers of graphite grains associated with Fe-Ni metal. Such graphite grains are considered to be products of parent body metamorphism [2, 3]. Isotopic compositions of carbon and nitrogen in graphite and in bulk meteorites give important clues to the parent body processes [e.g., 3-5]. We have initiated a mineralogical, Cand N-isotopic, and chemical study of graphite in KLE98300 and the bulk meteorite. This study should provide information on parent body processes of enstatite chondrite parent bodies. Here we report the results of noble gas and nitrogen analyses of the bulk meteorite as the beginning of our comprehensive study. Experimental: We measured noble gases and nitrogen in two ways: stepped pyrolysis and total extraction. A 66.22mg sample was used for stepped pyrolysis at 500, 900, 1200, and 1700°C. A 27.79mg sample was used for total extraction at 1700°C. Concentrations and isotopic ratios of noble gases and nitrogen were measured with a MAP215-50 mass spectrometer [6]. Results and Discussion: Ne is mostly cosmogenic except for some atmospheric-Ne released at 500°C. Elemental ratios in this fraction also show the presence of atmospheric gases (Fig. 1; [7]), indicative of terrestrial contamination. With increasing temperatures, elemental ratios decrease towards the origin (Fig. 1). In the 1200 and 1700°C fractions, data plot below subsolar, characteristic for E4-6 chondrites [8, 9] and even below Q [10]. The low Artrapped/Xe ratios suggest the presence of sub-Q gases (Ar/Xe=37±18; [9]). Sub-Q gases are characteristic for solar-gas-free E3 chondrites and are believed to originate from fractionation of Q-gases [9]. Xe isotopic ratios in the 500 and 900°C fractions plot between Xe-Q [10] and -Air [11] (Fig. 2). In the 1200 and 1700°C fractions, Xe isotopic ratios are close to those of Xe-Q, but not to those of Xe in E4-6 chondrites with subsolar gases [8, 9] (Fig. 2). Small contributions of cosmogenic-Xe are seen in these fractions (not shown in Fig. 2) and of Xe produced by fission of Pu [7] in the 1700°C fraction (Fig. 2). The low Artrapped/Xe ratios in the 1200 and 1700°C fractions and Xe-Q like isotopic ratios in these fractions support the conclusion that sub-Q gases are fractionated Q-gases [9].


Objective To observe the incidence and degree of phlebitis in patients receiving hot-wet compression with magnesium sulfate following peripherally inserted central catheters( PICC) at different time points and evaluate the opportune administration of hot-wet compression with magnesium sulfate. Methods Ninety cases of malignant lymph adenoma with PICC receiving chemotherapy were divided into 3 groups according to different opportunity of hot-wet compression with magnesium sulfate:experiment groupⅠ,experiment group Ⅱ and control group. experiment groupⅠ received the hot-wet compression immediately after PICC operation,experiment group Ⅱ received the hot-wet compression at 48 hours after PICC operation,while the control group received the hot-wet compression after the occurrence of phlebitis. The incidence and degree of the phlebitis in each group were observed. Results The incidence and degree of phlebitis were lowest in the experiment group Ⅰ,followed by experiment group Ⅱ and the control group. The difference among them was statistical significance. Conclusion The hot-wet compression with magnesium sulfate show a great effect for preventing phlebitis following PICC,and the using of hot-wet compression immediately after PICC operation can achieve a best efficacy as compared to other time points.


This i.,aper aims at presenting a model for developing teacher edueation eurricula in Turkish universities.The components of the model are preparation, implementation and evaiuation. The first component, preparation, is based on determining course objectives and student selection sys- tem, that is, cognitive entry behaviours and affeetive entry characteristics of student-teachers. The second component, implementation, is. based on determining subjeet-matter, professional and cu1turalcourses in teacher education eur- rieula. The last component of the model, evaiuation, is based on measurement and evaluation system of the train- ing programme. :,..


Model studies of hot and dense matter have suggested a rich phase structure of QCD at temperatures and quark chemical potentials of order ΛQCD. Our knowledge on the phase structure however remains limited and the description of strongly interacting matter does not reach a consensus yet [1]. In particular, properties of baryons near the chiral symmetry restoration are poorly understood. The realistic modeling of dense baryonic matter must take into account the existence of the nuclear matter saturation point, i.e. the bound state at baryon density ρ0 = 0.16 fm , like in Walecka type models [2]. Several chiral models with pure hadronic degrees of freedom [3, 4] have been constructed in such a way that the nuclear matter has the true ground state. An alternative approach is to describe a nucleon as a dynamical bound-state of a diquark and a quark [5]. In the mirror assignment of chirality to nucleons [6, 7], dynamical chiral symmetry breaking generates a mass difference between parity partners and the chiral symmetry restoration does not necessarily dictate the chiral partners to be massless. Mirror baryons embedded in linear and non-linear chiral Lagrangians have been applied to study their phenomenology in vacuum [6–8], nuclear matter [9, 10] and neutron starts [11]. Identifying the true parity partner of a nucleon is also an issue. In the mirror models N(1535) is usually taken to be the


The concept of wavefront curvature has been discussed extensively in the literature to relate surface seismic reflection data to subsurface geologic parameters. Developed initially for the case of homogeneous, isotropic, but arbitrarily dipping layered media, this technique has been extended to the inhomogeneous case. Now with the advent of new seismic techniques, such as vertical seismic profiling, three‐dimensional seismic methods, and shear‐wave techniques, the problem of velocity anisotropy is of growing concern to exploration seismologists. The essence of this paper is to extend the method of wavefront curvature to the "elliptically anisotropic" case in which the ray velocity varies elliptically with the direction of propagation. A fundamental feature of wave propagation in the anisotropic medium is that the direction of propagation of the disturbance (or the ray velocity direction) generally differs from that of the wavefront (or the phase velocity direction). Based on the assumption of two‐dimensio...


rates highly might not satisfy another at all. Recognizing this problem, Pogrow states that his evaluations are &dquo;... useful for narrowing the range of systems (considered),&dquo; after which &dquo;school/ district personnel must conduct their own evaluation of leading contenders to determine which software best meets their particular needs. &dquo; (The May 1985 NASSP Bulletin includes criteria for evaluating educational administrative software.) A reader not familiar with computer terminology may have trouble following the text, which includes neither an index


Along with the development of technology in this globalization era, it is very easy for humans to obtain information, one of which is by accessing the development of kpop world. The more easy it is to get this information, causing teenagers to become fanatical about what they are idolizing. As a result of the teenage fanatics causes several positive and negative impacts on him. The cause of the drama series, music, fashion, cosmetics, culture, social media. The increase in the development of this newspaper wave is very necessary to be discussed and must be considered by parents in seeing the development of their children. In this journal the author discusses the positive and negative effects of this kpop development. Data taken by the author is obtained from books, journals, internet, newspapers. To address this and reduce adolescent fanaticism towards kpop, the writer shares the ways that parents need to do.


Aromatase P450 (CYP19) is an enzyme responsible for the conversion of androgens to oestrogens. We generated CYP19 knockout (ArKO) mice by targeted disruption of Cyp19 and studied the role of oestrogens in male reproductive ability. Approximately 85% of ArKO males were unable to sire offspring. However, no obvious difference was found in testicular and epididymal weights, numbers of sperm in the epididymis or the ability of sperm to fertilize eggs in vitro between wild-type and ArKO males. An examination of mating behaviour demonstrated that ArKO males showed an impairment in mounting behaviour against sexually mature females. The inability of more than 90% of ArKO males to sire offspring was reversed by repeated subcutaneous injections of 17beta-oestradiol when initiated on the day of birth. The effects of 17beta-oestradiol on reproduction were concentration dependent and evident when supplementation was initiated on day 7, but not on day 15 after birth. These findings suggest that oestrogens acting during neonatal life are required for normal mating behaviour in adulthood.


It should be noted that Belgium spins expressionism. pearling neutralizes age counterexample. Market information, despite the fact that on Sunday some metro stations are closed, uniformly illuminates the methodological Babouvism. Heterogeneous system, as has been observed at constant exposure to ultraviolet radiation, making primitive general cultural cycle. Concession excessively primitive forms the law of the outside world. Charismatic leadership The Politics of Schizophrenia: Psychiatric Oppression in the United States by David Hill pdf gothic excites little functional analysis.


The work presented in this paper is based on a novel integrated and compact hydraulic robotic actuator [1] (BIA patent- US20110085922), intended for the hydraulic humanoid robot HYDROiD. This actuator solves the problem of autonomy for hydraulic humanoid robots as it can be integrated to operate each joint separately. Thus, eliminating the need for a central hydraulic power pack. Also, due to its small size, it can be placed as near as possible to the robot joints to minimize the possible drawbacks of hydraulic actuation units. The main problem for this prototype came from its compactness, causing the inability to study the dynamic properties of this hydraulic actuator such as leakage, friction and compressibility. Therefore, any enhancement or modification for its tiny mechanical components for performance improvement is not possible. As it lacks a mathematical model that represent the dynamics of the system at hand. Here comes the contribution of this paper, where a detailed mathematical model for the actuator is presented and simulated using MATLAB/Simulink. To validate this model, a sim-mechanics model based on its actual CAD design was presented and the two models were compared to verify the deduced dynamic model for the system. The results showed the accuracy of proposed mathematical model as a vital tool to represent the actuator and enhance it in future prototypes.


ABSTRACT In this paper, we present a systematic approach to sketch map interpretation. The method decomposes the elements of a sketch map into a hierarchy of categories, from the material sketch map level to the non-material representational sketch map level, and then interprets the sketch map using the five formal representation spaces that we develop. These spaces (set, graph, metric and Euclidean) provide a tiered formal representation based on standard mathematical structures. We take the view that a sketch map bears information about the physical world and systematises this using extensions of existing formal ontologies. The motivation for this work is the partially automatic extraction and integration of information from sketch maps. We propose a set of ontologies and methods as a first step in the direction of a formalisation of partially automatic extraction and integration of sketch map content. We also see this work as a contribution to spatial cognition, where researchers externalise spatial knowledge using sketch mapping. The paper concludes by working through an example that demonstrates the sketch map interpretation at different levels using the underlying method.


The space launch industry is experiencing a tremendous transition from a government-dominated customer base to a commercial customer base. According to the Teal Group World Space Briefing, nearly 75 percent of satellites launched from 1997 to 2006 will be commercial satellites (Caceres 1997). Of these, the vast majority are commercial ventures in mobile communications, broadband multimedia services, or direct broadcast television satellites. With the majority of the demand for launch services coming from commercial satellite providers, the needs and demands of the commercial satellite community are taking an ever increasing role in the development and design of launch vehicle systems. The Atlas IIAR, the R indicating re-engined, specifically addresses the call from commercial users for increased performance to orbit with higher reliability and launch availability. Lockheed Martin's Atlas IIAR launch vehicle will play a significant and crucial role in the launch of commercial satellites over the next sever...


Abstract For vulcanization of fully saturated elastomers peroxide/coagent systems are commonly applied. Problems encountered with peroxides however, are reduced efficiency, especially in the presence of plasticizing oils, and unwanted side reactions. In this paper diazides are presented as alternatives to peroxide vulcanization systems, particularly in combination with the use of plasticizing oils. The performance of three diazides; tri(ethylene glycol)-di(azidoformate) (GDAF), 4,4′-isopropylidenediphenyl azidoformate (4,4′DAF) and 1,3-benzenedisulfonyl azide (1,3BDSA) is investigated. For the evaluation of the practical product performance, carbon black filled and oil extended compounds of EPM and EPDM-rubbers are used. It is also investigated how the presence of carbon black and plasticizing oil influences the diazide reaction kinetics.


In order to clarify the differe nces in photosynthesis characteristics of tea tree between forest-tea(Choerospondias axillaris-Camellia sinensis) compound system and pure tea plantation,the photosynthetic parameters and fluorescent parameters of tea leaves from the two habitats were studied in Kaihua County,Zhejiang Province.The results showed that the maximum net photosynthetic rate(Pmax),light compensation point(LCP),light saturation point(LSP) and dark respiration rate(Rd) of tea tree had no significant differences between pure tea plantation and forest-tea compound system(P0.05),but the apparent quantum efficiency(AQE) of tea tree in pure tea plantation was significantly higher than that in forest-tea compound system(P 0.05).The Fv/Fm,the Fv'/Fm',the Fv/F0 and the qN also had no significant differences between pure tea plantation and forest-tea compound system(P0.05),but the ETR and the qP of tea tree in pure tea plantation was significantly higher than that in forest-tea compound system(P 0.05).Therefore,the light utilization efficiency of tea tree was not greatly influenced by C.axillaris-C.sinensis compound system.


The paper deals with Activity-Based Costing (ABC) and the related Activity-Based Management (ABM) as one of the modern approaches to cost management. From the eighties of the last century there is growing interest on ABC/M – not only from academicians, as applications are growing also in companies, including small and medium-sized enterprises (SME). In this paper we identify possibilities and limitations of ABC/M usage in SME and we recommend using this system for medium-sized manufacturing firms in competitive environment, with diversified production and higher indirect costs, requiring useful and precise information for decision making.


The effect of nitrogen sources on whitefly, Bemisia tabaci Genn. in chilli, Capsicum annuum L. were conducted at S.K.N. College of Agriculture, Jobner, Rajasthan during Zaid, 2014 and 2015. The different sources of nitrogen the treatments were T4 100% N through NC, T3 75% N through NC + 25% through urea, T8 100% N through VC and T7 75% N through VC + 25% through urea resulted in the population of 3.82 to 4.08 whitefly/ three leaves were found most effective against the pest and the maximum fruit yield of chilli, C. capsicum was also obtained in these treatments, while the treatments of T10 50% N through FYM + 50% through urea and T9 25% N through FYM + 75% through urea was found least effective.


Procrastination is the volitional delay of an intended task, despite believing that delay will be harmful. While not all delay is attributable to procrastination, procrastination is fundamentally characterised by delay. As much as 90% of the population have experience with procrastination, with around 20% in the general population and 50% of university students reporting problematic levels of chronic procrastination. Compared to their non-procrastinating peers, chronic procrastinators report lower levels of wellbeing, higher rates of depression, higher rates of alcohol and other drug use for coping, and poor health adjustment. Procrastinators tend to have lower salaries, shorter durations of employment, and a greater likelihood of being unemployed or underemployed. There is also a direct economic impact on the workforce, with office workers found to spend an average of 1.5 hours per work day procrastinating.
Despite its prevalence, the variability of tasks, time available, subjectivity, and individual differences render procrastination difficult to observe as it happens. Consequently, while correlates, antecedents, effects, and types of procrastination have been widely investigated, progress in this field is limited by several factors. In particular, few studies have accurately quantified delay associated with procrastination over time. As a consequence, there is limited evidence supporting the ability of trait measures of procrastination to predict delay, and few interventions aimed at reducing procrastination have been clearly associated with reduced delay.
Recent developments in smartphone technology and Experience Sampling Method (ESM) applications have enabled intensive longitudinal observations of such dynamic phenomena with relative ease; however, such methodology and statistical modelling of delay have yet to be reliably applied to the study of procrastination.
To address the challenge of observing delay associated with procrastination, I conducted three studies of students enrolled in a 1st year psychology course: a small pilot study (N = 24) and two larger scale replications (Ns = 80 and 107) focusing on intensive longitudinal measurement of delay, procrastination scale validation, and an intervention to reduce procrastination respectively. Participant ages ranged from 17.38 to 65.85 years (M = 23.85, SD = 9.49) and 75% identified as female. Each study included a baseline survey of demographic and trait procrastination and personality variables, an ESM phase comprised of 28 SMS surveys over 14 days in the lead-up to submission of an assignment worth 30% of the course grade, and the collection of assignment submission date and mark from the course convenor. Participants in the ESM phase were randomly allocated into either an intervention or control condition, with participants in both conditions reporting their assignment progress, completion intent, and affect regarding their assignment progress. Participants in the intervention, but not the control, condition were messaged at the end of each ESM survey with open reflection prompts designed to reduce procrastination. Studies 1 and 3 also included follow up interviews with a small subsample of participants (N = 8) to garner first-hand perspectives of participation in the ESM component of the studies. Through the application of multilevel model analyses, the presence of quantified delay curves in all three studies provides firm evidence that regular self-reporting of task progress using ESM is a robust and reliable method for measuring behavioural delay. The use of multilevel modelling in quantifying delay enabled the inclusion of mixed effects, where the predictive ability of several procrastination scales could be assessed. A trait measure of passive procrastination was found to reliably predict behavioural delay, whereas no association was found between a measure of active procrastination, a type of procrastination purported to be adaptive and deliberate, and delay. The intervention prompting regular reflection on factors thought to be related to procrastination that was embedded into the ESM phase of each study was found to significantly reduce delay in Studies 1 and 3, but not in Study 2. Between-study differences in this intervention effect were likely related to contextual differences as participants in Study 2 were aware that the research pertained to procrastination whereas those in the other studies were not informed of the focus on procrastination. In the follow-up interviews, participants reported that regularly reporting task progress, as well as the intervention reflection prompts, may have assisted with the reduction of procrastination. Analyses conducted into the relationships between trait procrastination, neuroticism, and state affect and delay revealed that neuroticism (emotional stability) moderated the relationship between trait procrastination and affect, and affect mediated the relationship between trait procrastination and task delay. Moreover, cross-lagged panel model analyses of inter-temporal changes in affect and delay showed that participants who reported greater task progress at an earlier time were likely to report higher positive affect at a subsequent time, whereas those reporting higher positive affect at an earlier time tended to report lower progress at a subsequent time.
Overall, the research offers three specific unique contributions to the body of knowledge. First, the use of ESM surveys of task progress is demonstrated to be a reliable method for measuring behavioural delay associated with procrastination. This is evidenced by the presence of accelerating delay curves, where assignment progress increases in a hyperbolic trajectory prior to a submission date. The reliable observation and modelling of delay is an oft-cited limitation of the field; thus, the replicated validation of this as a reliable method constitutes a valuable contribution. Second, multilevel mixed effects modelling is used to assess the ability of scales measuring different aspects of trait procrastination to predict behavioural delay, indicating that some trait procrastination measures are more predictive of behaviour than are others. The statistical method employed, and the use of task progress rather than study duration as the outcome, enabled the construct validity of the contentious 'active' form of procrastination to be challenged. This approach is proposed also to be a suitable method for assessing the behavioural efficacy of targeted interventions for reducing procrastination. Third, sending regular reflection prompts to randomly selected ESM recipients resulted in a significant reduction in behavioural delay in two of the three studies. This use of low-intensity reflection prompts delivered at a high-frequency demonstrates smartphone use can be an effective medium for reducing procrastination without the need for intensive approaches requiring considerable commitment from both practitioners and participants. This intervention design sets an example for reducing delay in academia, with the method likely capable of being extended, with adaptation, to procrastination in other areas such as health behaviour change, personal finance, and collective action.


The purpose of this study was to determine whether the results of KTAS(Korean Triage and Acuity Scale) triage classifier differ according to the occupations. We analyzed a total of 10,960,359 cases of data sent to the NEDIS from January 1st, 2016 to December 31th, 2017. The triage classifier were MD(Medical Doctor), R(Resident), INT(Intern), GP(General Practitioner), RN(Registered Nurses) and EMT(Emergency Medical Technician). The consistency between the initial triage and final triage results was the highest GP(98.9%) and the lowest INT(80.2%). The results of over-triage classification was the lowest by GP(0.6%) and the highest for INT(16.0%). Also, the results of under-triage classification was the lowest by MD, EMT(0.4%) and the highest for INT(3.8%). The results of KTAS triage classifier significantly differ from according to the occupations(p<0.001). Triage classification should not differ from according to occupations and skill. It is necessary to strengthen the classifier's capacity for accurate triage classifications.


Flueggeacosines A-C (1-3), three dimeric securinine-type alkaloid analogues with unprecedented skeletons, were isolated from Flueggea suffruticosa. Compounds 1 and 2 are the first examples of C-3-C-15' connected dimeric securinine-type alkaloids. Compound 3 is an unprecedented heterodimer of securinine-type and benzoquinolizidine alkaloids. Biosynthetic pathways for 1-3 were proposed on the basis of the coexisting alkaloid monomers as the precursors. Compound 2 exhibited significant activity in promoting neuronal differentiation of Neuro-2a cells.


. Undoped and Mn-doped ZnO ceramics were theoretically and experimentally investigated using specular infrared reflection method. It was shown that infrared reflection spectra can be modeled using the parameters explored for ZnO single crystals. For ceramic samples, it was shown that ZnO grains with orientation of the C -axis along the normal to the electric field ( C E   ) give the main contribution to IR reflection spectra. It has been ascertained that the surface roughness is manifested in these spectra mainly within the range 450…550 cm –1 giving negligible effect for the frequencies above longitudinal phonon frequency. This allowed the electrophysical parameters of ZnO crystallites to be evaluated. In the case of undoped ceramics, the obtained results were found to be consistent with the values of direct current measurements. This finding supports the utility of infrared spectroscopy for determination of the electrophysical parameters of polycrystalline ceramic materials. For Mn-doped ceramic samples, the conductivity value measured using the direct current method was found to be essentially lower than those determined from simulation of infrared reflection spectra. This phenomenon was explained by barrier formation at the grain boundaries in Mn-doped ZnO ceramics.


The spoils of refined flamenco dancing, substantially improves the stability of the foot inside the shoe, with great application in flamenco dance and other disciplines in which a shoe or boot booty type is used. Its main application is as a preventive measure injury ankles and knees caused by the movement of the foot inside the shoe, boot or booty. # The spoils of refined flamenco dance consists of two or more belts made of hypoallergenic, synthetic or natural material arranged cross or parallel to one another form, with one or more closures or clasps. The route of these belts of anchoring between the sole and sobresuela footwear, to surround the ankle, so that secure the foot both the instep up to the gap that exists near the heel of the spoils, as ankle .


With an extensive history of environmental policies and protections, Costa Rica has become an environmental leader to the rest of the world. Most administrations in Costa Rica have environmental issues on their agendas, which demonstrates the country's commitment to environmental conservation and protection. These efforts can be observed in their transition from traditional forms of tourism to what's known as ecotourism. This form of tourism has been gaining a lot of international interest, and there is a debate on whether it is beneficial as a sustainable development model. This paper will take a step back and address the question of what are the necessary conditions for ecotourism to emerge successfully in the first place. By using Costa Rica as an example, the paper concludes that strong government support; general and local environmental awareness and education; proper management, operational capacities, and institutions; and effective involvement and communication of the local communities; are all conditions that facilitated the emergence and success of ecotourism.


The combustion of anthracite and other low-volatile coals for power production is discussed in the article. The Foster Wheeler arch-fired steam generator design and operating characteristics are emphasized. Design and operating data are provided for 250-500 MWe units in Spain and China. Thermogravimetric and chemical analyses of fuels and chars are tabulated, and reactivity indices (temperature at which devolatilization and self-sustaining combustion occurs) are listed.


We thank Madias for his interest in our work1 and the interesting points he raised. According to Madias2 and based on experimental work in animals, it has been suggested that aspirin could prevent infective endocarditis. Hypothetically, platelets are involved when bacteria adhere to abnormal or damaged endothelium by acting together with fibrin, extracellular matrix proteins, and surface adhesions on bacteria. It is therefore possible that drugs targeting platelet function could reduce the risk of infective endocarditis. Madias correctly noted that our study was …


We report a case of a 55-year-old man with a 6.5 mm right posterior cerebral artery (PCA) aneurysm. Upon attempted Guglielmi detachable coil embolisation, the guidewire was lodged in a perforating branch of the right PCA and attempted retractions were unsuccessful. The retained guidewire was left in the patient. The patient died 10 weeks later due to a perforation that dissected through the wall of the ascending aorta resulting in haemopericardium.


Developing efficient, stable, and inexpensive electrocatalyst for oxygen evolution reaction (OER) is significant for development and utilization of clean energy. Defects in electrocatalysts strongly impact their chemical properties and can...