Three kilometers northwest of Mammoth Lakes, California there is a crack known as the "Earthquake Fault" which is locally up to 20 m deep. The feature is located at the southern end of, and oriented parallel to, the Mono-Inyo Craters. It is mapped and popularly called a fault, but based on recent volcanic activity in the area and the lack of measured motion on the fault, it may actually be a volcanic fissure. To determine the degree of faulting and fissuring, points on both walls that showed evidence of strike-slip, dipslip, or extensional movement were labeled. The points were then placed in a 3-D model; their relative positions were broken down into vector components to isolate extensional, dip-slip, and strike-slip movement. The crack exhibited significant extensional movement at both testing locations (1.34 m at location A and 2.11 m at location B). At location A the crack showed minimal right-lateral strike-slip movement and minimal normal dip-slip movement (0.12 m and 0.17 m ). However, at location B the crack showed notable right-lateral strike-slip movement and notable normal dipslip movement (0.90 m and 1.27 m). These data are consistent with a propagating dike, not tectonic movement, forming the fissure. Differences in local stress could account for different strike-slip and dip-slip movement. This makes the term Earthquake Fault a misnomer. INTRODUCTION Just outside of the popular ski town of Mammoth Lakes the National Forest Service advertises the Earthquake Fault, an impressive gorge locally up to 20 m deep (Fig. 1). Despite the potential hazards of a crevice located only 3 km northwest of Mammoth Lakes, how the feature formed is not well understood. Sharp and Glazner (1997, p. 255) discounted the likelihood of an origin by thermal contraction because the "host lava is too old . . . it is unlikely that open cracks could have survived for 50,000 years or more without filling with glacial debris, pumice from nearby eruptions, or loose rock". Furthermore, they ruled out a landslide origin based on local topography. As the name suggests, the crevice may have opened due to faulting, a plausible explanation given recurrent tectonic activity in the region. The Earthquake Fault is situated along the eastern margin of the Sierra Nevada Range, where there are active strike-slip and normal faults due to the northwest translation of the Sierran microplate relative to the rest of North America (Unruh et al., 2003). The stress due to this translation could potentially be the cause of the Earthquake Fault (Bailey, 2004). Others hypothesize the Earthquake Fault is related to magmatic, not tectonic, activity. The feature, located just south of the Inyo Craters, is part of an extensive system of faults and fissures that lie parallel to the Mono-Inyo volcano chain (Benioff and Gutenberg, 1939). Through the drilling of a slant hole between Obsidian Dome and Glass Creek Flow — two features located in the northern section of the Inyo chain— Eichelberger et al. (1985) encountered the dike that fed Obsidian Dome. Their findings suggest that episodic ascent of rhyolitic magma created explosive volcanism and fed the Inyo Craters 650-550 yr B.P. Due to the parallel alignment of the faults and fissures along the dike-fed Mono-Inyo Craters, Mastin and Pollard (1988) proposed that the pressure of a subsurface dike intrusion not only created the volcanic chain, but also created the related fissures and faults. Mastin and Pollard represented this subsurface dike intrusion using a flour and sugar model. Through their experiments, they found that fissures and faults formed both parallel to and directly above the model dike, similar to the situation along the Mono-Inyo system. Even though the dike did not penetrate to the surface everywhere, the pressure of the expanding magma could have caused inelastic deformation near the Earthquake Fault (Reches and Fink, 1998). Our research aims to synthesize these previous studies and determine the factors that contributed to formation of the Earthquake Fault using 3-D modeling and analysis. Significant strike-slip or dip-slip movement at the Earthquake Fault would suggest tectonic activity. However, we hypothesize the feature will exhibit primarily extensional opening above a subsurface dike intrusion. This information is pertinent to the safety of nearby residents and tourists given its potential association with future eruptions or earthquakes. Figure 1: Faults and fissures of the Mono-Inyo region and their proximity to the town of Mammoth Lakes. Adapted from Reches and Fink, 1998.


Experimental research of new optical fiber sensors for monitoring civil infrastructure systems is presented. The proposed optical sensors employ a vibrating wire shoe tension can be modulated by external force, strain, or vibration and is translated into the change in the wire vibration frequency. The wire vibration frequency is detected by light sent to and reflected from the wire through an optical fiber cable. Compared to other existing optical fiber sensors which tend to suffer from the lack of reliability and robustness, the proposed sensors have two significant advantages: one is that the sensing head is a vibrating wire (rather than an optical fiber), which can sense a specific physical quantity without interference from miscellaneous effects; the other is that the wire vibration is a well understood physical phenomenon. In fact, with a high level of reliability, its frequency is optically measured and transmitted to recording and other devices through the optical fiber without attenuation or distortion. These advantages make the sensor system simple, reliable and robust, and hence more readily deployable in civil infrastructure applications.


The authors present the results of experimental measurements of the radio frequency phase as a function of cathode voltage for an eight-beam four-cavity multiple-beam klystron (MBK) operated at a driven frequency of 3.25 GHz. The phase-pushing factor was measured in both the small- and large-signal regimes of amplifier operation and was found to be 0.0134deg/V and 0.0148deg/V, respectively. The experiment was also modeled with a simple analytic function and with telegraphist's equations solution for linear beam amplifiers, a multiple-beam 2.5-D nonlinear klystron code, with both methods yielding good agreement with the measured data. The low values for the phase-pushing factor are a benefit of the MBK's high-perveance operation that results in a shorter circuit length relative to single-beam devices of comparable power. These advantages contribute to the growing interest in the use of multiple-beam devices for high-power phase-sensitive applications such as advanced radar and high-data-rate digital communications


Pruritus is a common and distressing skin disorder and treatment of itch is a daily problem for millions of people. Available therapies are ineffective and there is an urgent need for new topical treatments to relieve itch. Studies were undertaken to identify the optimal concentration of a natural therapeutic for the relief of itch and to assess the safety of this agent in dermal application with six volunteers. In the initial study, six volunteers with self-diagnosed atopic dermatitis applied a lotion containing concentrations ranging from 5 to 25 weight percent of 1200 Gelatin Dissolving Units (GDU) bromelain to their skin and noted any discomfort caused to the area and the amount of symptomatic relief that was obtained. Based on this study, 15 weight percent of 1200 GDU bromelain suspended in lotion was selected for further testing. For the safety study, a total of thirty subjects were randomized into three pools and participants in each pool applied the lotion to their arms, backs, or legs on a daily basis. After four weeks, all the participants had completed the study and none had reported an adverse event. The lotion was found to be safe and effective when applied topically on a daily basis.


With China's entry into WTO, every enterprise and manager would face a harsh reality, and as for enterprise, it is not only to come into contact with the international in environment, policy, law and market, but also there will be a great transformation in mechanism of business operation, mode and contents of management in enterprise. upon which the management training will also face a serious challenge accordingly.


AbstractSoil colloids play critical roles during the fate and transport of micropollutants (e.g., pesticides and hormones) due to their high sorption affinity and mobility. In this study, the authors developed a centrifugation and mass balance–based methodology for studying sorption of testosterone to soil colloids of different size fractions (DSFs). The method should allow one to conduct the sorption tests with the whole soil first and then separate soil colloids of DSFs to evaluate their contributions to sorption. Results indicate the colloids diameter ranges (i.e., 900–600, 600–400, and 400–200 nm) can be controlled by a group of series centrifuge conditions (i.e., speed and time). The sorption affinity of soil colloids for testosterone is three times higher than that of the bulk soil and increases significantly with decreasing diameter size because of the difference of specific surface area and organic carbon content. The authors propose that the centrifuge condition of 2,844 relative centrifugal forc...


Much music is conceived physically under the broader concept of resonance. This includes the conception of the physical materials of music as being embodied in the geometry of vibrations of air molecules in a bounded space, inside which the concept of the "outside" of this space is meaningless. I am interested in the properties of universality that involve music unbounded by this multi-dimensional, enclosed continuum. We remember the one eyed, sessile philosopher who could only conceive of a crude elliptic, two-dimensional space. The three-dimensional form of tactual space is resultant from the combination of images from two eyes and is given meaning that is conditioned in part by the semi-circular canals of the ear, the changes of which are cross or cross-correlated with the dynamic, myogenetic forms of extension, contraction, and resistance to gravity. What, then is the latest sense, or abstract "third eye" which will enable us to create a music that articulates itself physically through universals of experience with all of space. Kant maintained that space is not an empirical concept derived from external experience, but a framework already existing in the mind without which no external phenomena would be possible. Poincaré points out that, just as the Principle of Relativity tries to show us that it is impossible by any means to obtain knowledge of absolute motion, so, it is theoretically impossible to determine what are the qualities of matter as "distinct" from those of space. Therefore, it is beyond our power to obtain knowledge of absolute space.


The problem of cross border interchange and of exchange capacity allocation has gained an increasing importance because of existing price gaps between the different countries and of limited exchange capacity. The European Transmission System Operators (ETSO) committee has issued a sequence of documents illustrating the guidelines for efficient and economic assignment of the available cross border capacity. An example of successful multi-market coordination is given by the trilateral market coupling system developed by the TSOs of France, Belgium and the Netherlands. The aim of the present paper is that of finding a procedure able to make results from market coupling as close as possible to those furnished by single electricity pool.


In this monthly advice column, Phyllis Fagell answers questions from educators who are frustrated with distance learning during the COVID-19 pandemic — and with managing other people's frustrations about it. A principal wants to know how to be supportive of teachers and staff who are unhappy with district-level decisions while also pushing them to do the work that must be done. A teacher is having trouble listening to parents' complaints about distance learning, especially when she knows they're right.


Objectives The study aimed to determine whether exposure to a volcanic eruption was associated with increased prevalence of physical and/or mental symptoms. Design Cohort, with non-exposed control group. Setting Natural disasters like volcanic eruptions constitute a major public-health threat. The Icelandic volcano Eyjafjallajökull exposed residents in southern Iceland to continuous ash fall for more than 5 weeks in spring 2010. This study was conducted during November 2010–March 2011, 6–9 months after the Eyjafjallajökull eruption. Participants Adult (18–80 years of age) eruption-exposed South Icelanders (N=1148) and a control population of residents of Skagafjörður, North Iceland (N=510). The participation rate was 72%. Main outcome measures Physical symptoms in the previous year (chronic), in the previous month (recent), General Health Questionnaire (GHQ-12) measured psychological morbidity. Results The likelihood of having symptoms during the last month was higher in the exposed population, such as; tightness in the chest (OR 2.5; 95% CI 1.1 to 5.8), cough (OR 2.6; 95% CI 1.7 to 3.9), phlegm (OR 2.1; 95% CI 1.3 to 3.2), eye irritation (OR 2.9; 95% CI 2.0 to 4.1) and psychological morbidity symptoms (OR 1.3; 95% CI 1.0 to 1.7). Respiratory symptoms during the last 12 months were also more common in the exposed population; cough (OR 2.2; 95% CI 1.6 to 2.9), dyspnoea (OR 1.6; 95% CI 1.1 to 2.3), although the prevalence of underlying asthma and heart disease was similar. Twice as many in the exposed population had two or more symptoms from nose, eyes or upper-respiratory tract (24% vs 13%, p<0.001); these individuals were also more likely to experience psychological morbidity (OR 4.7; 95% CI 3.4 to 6.5) compared with individuals with no symptoms. Most symptoms exhibited a dose–response pattern within the exposed population, corresponding to low, medium and high exposure to the eruption. Conclusions 6–9 months after the Eyjafjallajökull eruption, residents living in the exposed area, particularly those closest to the volcano, had markedly increased prevalence of various physical symptoms. A portion of the exposed population reported multiple symptoms and may be at risk for long-term physical and psychological morbidity. Studies of long-term consequences are therefore warranted.


A new class of unsaturated polyesters of diarylidenecycloalkanones con taining the azomethine group in the polymer backbone has been prepared. Synthesis involved the interfacial polycondensation of 4,4'-[1,4-phenylene bis (methylidynenitrilo)] dibenzoyl chloride II with 2,5-bis(p-hydroxybertzylidene) cyclopentanone III, 2,5-di vanillylidenecyclopentanone IV, 2,6-bis(p-hydroxybenzylidene) cyclohexanone V or 2,6- divanillylidenecyclohexanone VI at ambient temperature. The resulting polyesters were characterized by elemental analyses, IR spectroscopy, solubility and viscometry measure ments. The thermal properties of the polymers were evaluated by thermogravimetric analysis and differential thermal analysis measurements and correlated to their structu ral units. The crystallinity of all polymers was examined by X-ray analysis. In addition, the electrical properties of all polyesters were measured.


PURPOSE
Arsenic trioxide (ATO) targets multiple pathways in malignant cells, resulting in the promotion of differentiation or in the induction of apoptosis. The antitumor activity of ATO on retinoblastoma was investigated.

METHODS
Human retinoblastoma cells were incubated with various ATO concentrations. The antiproliferative effect of ATO was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, and the effect of ATO on cell-cycle progression was validated by flow cytometry. At a low concentration, the ATO-induced differentiation of retinoblastoma cells was evaluated by neurofilament expression and extracellular signal-regulated kinase (ERK)1/2 activation, which was confirmed by the inhibition of ERK1/2. At a high concentration, ATO-induced H(2)O(2) production was investigated with the cell-permeable fluorescent dye 2'7'-dichlorofluorescein-diacetate, and the relationship of ATO-induced H(2)O(2) production with caspase-3-dependent apoptosis was validated by Western blot and 4'6-diamidino-2-phenolindole staining, which was confirmed by reactive oxygen species (ROS) inhibition. The effect of ATO on tumor formation was assessed with an orthotopic animal model of retinoblastoma.

RESULTS
The antitumor activity of ATO in retinoblastoma was related to two main mechanisms, differentiation and apoptosis, which were determined by the level of ATO. At a low dose (<or= 1 microM), ATO induced the differentiation of retinoblastoma cells through ERK1/2 activation, whereas ROS generation by a high dose (>or= 2 microM) of ATO induced apoptosis in retinoblastoma cells. Moreover, ATO at low and high doses effectively inhibited tumor formation.

CONCLUSIONS
These results suggest that ATO can be used as an effective alternative therapeutic for the treatment of retinoblastoma.


The PCB-degrading enzyme was isolated and purified from the fermentation broth of Staphylococcus epidermidis by ammonium sulfate precipitation,dialysis and Sephadex G-150 gel chromatography.The activity of the PCB-degrading enzymes could increase to 442.29 U/mg after purified by 30%~80% of(NH4)2SO4 precipitations,and could increase to 480.75 U/mg after dialysis.The activity could finally increase to 6 903.57 U/mg after purified by gel chromatography,as the purification fold was 35.9;and the recovery rate was 30.56%.The optimum pH of PCB-degrading enzyme was 7.0,and it was stable at pH 6.0~9.0 and 30~45 ℃.Cu2+ and Fe2+ had some inhibition to this enzyme.


Optical-microwave double resonance measurements were carried out to find the hyperfine structure constants of the v = 0 level of the BaI X 21: + state. These were combined with subDoppler optical measurements of the BaI c 2n_x 21:+ (0,0) band in order to derive the hyperfine structure constants of the excited state. We have determined the following molecular constants (in MHz) where the numbers in parentheses represent one standard deviation in a least squares fit: for the Bal X 21:+ state, y" = 75.8501 (33), b " = 93.117(19), c" = 52.170(54), and eQq" = 33.62(12), and for the Bal C 2n state, a' = 263(53), b' + c' = 430(212), d' = 66.7(1.4), and eQq' = 214(11). The Fermi contact interaction and the electric quadrupole coupling constants for both the BaI X and estates appear to arise from the distortion of closed-shell I orbitals by the field of the Ba + ion. In the BaI X state, the charge distribution on the Ba + center is directed away from I while in the C state toward 1-.


A general method is proposed for testing the fit to any member of the invariant under convolutions family of count models, parameterized by mean and variance. The test statistics, which are of the weighted L2-type, exploit the specific structure of the corresponding probability generating function. Their asymptotic null distribution is obtained, and the consistency of the tests is studied. As an example, the generalized Hermite distribution, a specific member of this family, is analysed. In this case, two methods of estimation of the parameters are considered, for which limit statistics are obtained as the decay of the weight function tends to infinity. The performance of a parametric bootstrap version of the method is investigated via Monte Carlo.


Electrical stimulation is known to cause activation in mammalian oocytes, possibly by eliciting an elevation in intracellular calcium (Ca2+). This study reports intracellular Ca2+ concentrations in mature rabbit oocytes using the Ca2+ indicator fura‐2. Calcium levels were determined prior to, during, and after the administration of an electrical pulse (3.6 kV/cm for 60 μsec). Baseline Ca2+ levels ranged from 30 to 90 nM. The intracellular Ca2+ transient evoked by a pulse, peaked at 11 sec, was highly variable in amplitude (40–300 nM) and returned to prepulse levels within 300 sec. Electrically stimulated oocytes did not exhibit repetitive Ca2+ transients. The size of the cytoplasmic Ca2+ rise was influenced by the duration of the pulse, the field strength and the concentrations of external Ca2+ (P < 0.05). Oocytes electrically stimulated in the presence of 100 μM CaCl2, which evoked Ca2+ transients with a mean magnitude of 120 nM, activated at a higher rate (P < 0.05) than oocytes stimulated in the presence of either higher or lower levels of external Ca2+. Although oocytes electrically shocked at 16–18 hr after administration of human chorionic gonadotropin (hphCG) activated at a lower rate than oocytes stimulated at 22–24 hphCG (P < 0.05), their intracellular Ca2+ response to the pulse was similar (P < 0.05). These results indicate that electrical pulse parameters and extracellular Ca2+ concentrations can be used to modulate intracellular Ca2+ levels and optimize oocyte activation rates. Furthermore, the data suggest that as the oocyte ages it becomes more responsive to a given intracellular Ca2+ elevation. © 1992 Wiley‐Liss, Inc.


A study on kampung chickens was undertaken to investigate the influence of scheduling of feeds by reducing protein levels during the various phases of growth of the birds until market age, on carcass characteristic and meat quality. A total of 62 3-week-old female kampung chickens were reared in two-tier wire floor cages with two chicks per cage for eight weeks. The chicks were randomly divided into four treatment groups (single-phase, 2-phase, 3-phase and 4-phase) and fed with step-down dietary protein levels (19, 17, 15 and 13%) accordingly. At the end of the study period, ten birds per treatment were randomly sampled for analysis. Carcass yield and component parts (breast, thigh, drumstick, wing, abdominal fat, back and neck) of the birds were determined as percentages of live weights. Meat chemical composition from breast muscles was determined for dry matter, crude protein and crude fat content. No significant differences were found in the percentages of carcass yield, component parts, dry matter, crude protein and crude fat contents between the four phases. It is concluded that phase feeding did not adversely affect carcass yield and meat chemical composition. This feeding strategy could therefore be an economical practice for rearing kampung chickens without sacrificing carcass yield and meat quality.


Low‐voltage operating organic electronic circuits with long‐term stability characteristics are receiving increasing attention because of the growing demands for power efficient electronics in Internet of Things applications. To realize such circuits, inverters, the fundamental constituents of many circuits, with stable transfer characteristics should be designed to provide low‐power consumption. Here, a rational inverter design, based on fully screen printed p‐type organic electrochemical transistors with a channel size of 150 × 80 µm2, is explored for driving conditions with input voltage levels that differs of about 1 V. Further, three different inverter circuits are explored, including resistor ladders with resistor values ranging from tens of kΩ to a few MΩ. The performance of single inverters, 3‐stage cascaded inverters and 3‐stage ring oscillators are characterized with respect to output voltage levels, propagation delay, static power consumption, voltage gain, and operational frequency window. Depending on the application, the key performance parameters of the inverter can be optimized by the specific combination of the input voltage levels and the resistor ladder values. A few of the inverters are in fact fully functional up to 30 Hz, even when using input voltage levels as low as (0 V, 1 V).


Arithmetic Logic Unit (ALU) is one of the most crucial part of all the digital circuits that is used to perform arithmetic and logical operations. An energy and power efficient ALU is designed in this paper by employing different energy and power efficient techniques. ALU is designed on ISE project navigator of Xilinx software and power analysis is done on X Power Analyzer. Two energy efficient techniques named as Frequency scaling and Input/Output (I/O) standard scaling are employed on ALU. In the frequency scaling technique, frequency range of the design is varied from Mega Hertz (MHz) to Tera Hertz (THz) and power analysis is done to figure out the most efficient frequency in terms of power consumption. Power analysis is also done at different I/O standards of Low Voltage Complementary Metal Oxide Semiconductor (LVCMOS) logic family to find out the most power efficient IO standard. The device is operated on ARTIX-7 FPGA technology with a channel length of 28 nano meters (nm). It has been concluded from results that maximum power is being saved at LVCMOS 33 I/O standard at a frequency of 1MHz.


The article discusses topical issues of training future health care specialists at different stages of professionalization. Particular attention is paid to the stage of training in residency, when not only the formation and development of the activity professionalism, but also the personality professionalism of the future doctor is carried out.Important knowledge during training in residency and postgraduate institution is acquired by the need for self-actualization and value orientations of trainees in the structure of an individual's professionalism. The work emphasizes that in the preparation of future doctors, the resolution of indicated problem can successfully occur not only under the influence of central medical disciplines for training highly qualified personnel. Today, many researchers focus on the role of humanitarian disciplines, which have a significant impact on the personal and professional aspects of training. In this case, what it involves is the mastering of Pedagogy and Educational Psychology programs.The study found that the participation of residents in training in two educational humanitarian programs provides favorable transformation of value orientations, reflecting the need for self-actualization, acceptance of medical practice values, and value attitude to the professionalism of a doctor. The data obtained indicate the need for purposeful use of pedagogy and psychology to improve the professionalism of future doctors during preparation for professional activity.


Predicting both optimal and reliable aircraft turnaround time is one of the most critical tasks in ACDM flight scheduling plans. Considering the effects of randomness and fuzziness on the turnaround process duration, we transform the probability distribution of well-fitted sub-processes into a cumulated density function, equivalent to the fuzzy membership function (FMF), then identify the fuzzy membership grade of each turnaround sub-process by goodness-of-fit. Based on the Critical Path Method (CPM) technique and fuzzy set theory, the turnaround time, considering stochastic effects, is evaluated using the fuzzy critical path method (FCPM). To validate this calculation, we constructed the FMF from historical data and compared it with FCPM-based turnaround times. In addition, we utilize these historical data to generate fuzzy sets of different arrival delays using Frankfurt airport data of summer 2017 and conclude that delays are positively correlated with the FCPMbased turnaround process through a linear regression model. Keywords—Decision Support System; Airline Ground Operations; Uncertainty; FCPM; Fuzzy Decision Making


During development and maturation of skin and its derivatives, bundles of extracellular filamentous elements appear, which traverse a cross section of dorsal skin from deep mesenchyme to the basal lamina of the dermo-epidermal junction. Observations on freshly fixed tissue and on pieces of skin grown in culture for three to five days, especially in areas where the presence of anchor filaments could be predicted, indicate that the filaments most likely originate from fibroblasts which are usually located in a stratified layer of the deeper mesenchyme. The distal end, or termination, appears to be the basal lamina into which the anchor filament blends and is dispersed.

The anchor bundles are composed of long thin filaments in close aggregation and they demonstrate cross-striations separated by approximately 400 A in the midportions, and up to 600 A near their origin and termination. The diameters of the bundles average approximately 0.33 μ at their thickest part. However, at or near their origin, they measure 0.2 μ or less in diameter.

The analogy of the filaments to a growing tree is suggested in that, the roots, or origins of the filaments are thin, tortuous and in many cases widely separated. In certain areas they converge into one main trunk which tapers toward their termination in the basal lamina. The observations also suggest that some bundles may have several roots or rootlets, while others have only one or two.

Although collagen is often seen close to the bundles, the data indicate that the latter are distinct from, and not derived from collagen.


The PHOENIX project aims to examine the impact of structural changes to the health and care system in England on the functioning of the public health system, and on the approaches taken to improving the public's health.

The scoping review has now been completed. During this phase we analysed: Department of Health policy documents (2010-2013), as well as responses to those documents from a range of stakeholders; data from 22 semi-structured interviews with key informants; and the oral and written evidence presented at the House of Commons Communities and Local Government Committee on the role of local authorities in health issues. We also gathered data from local authority (LA) and Health and Wellbeing Board (HWB) websites and other sources to start to develop a picture of how the new structures are developing, and to collate demographic and other data on local authorities. A number of important themes were identified and explored during this phase. In summary, some key points related to three themes - governance, relationships and new ways of working - were:

The reforms have had a profound effect on leadership within the public health system. Whilst LAs are now the local leaders for public health, in a more fragmented system, leadership for public health appears to be more dispersed amongst a range of organisations and a range of people within the LA. At national level, the leadership role is complex and not yet developed (from a local perspective).
Accountability mechanisms have changed dramatically within public health, and many people still seem to be unclear about them. Some performance management mechanisms have disappeared, and much accountability now appears to rely on transparency and the democratic accountability that this would (theoretically) enable.
The extent to which 'system leaders' within PHE are able to influence local decisions and performance will depend on the strength of relationships principally between the LA and the local Public Health England centre. These relationships will take time to develop.
Many people have faced new ways of working, in new settings, and with new relationships to build. Public health teams in LAs have faced the most profound of these changes, having gone from a position of 'expert voice' to a position where they must defend their opinions and activities in the context of competing demands and severely restricted resources. Public health staff may require new skills, and may need to seek new 'allies' to thrive in the new environment.
HWBs could be crucial in bringing together a fragmented system and dispersed leadership.

The next phase of data collection will begin in March with the initiation of case study work. National surveys will be conducted in June/July this year (2014), and at the same time the following year. In this work, we will further explore the following themes: relationships, governance, decision making, new ways of working, and opportunities and difficulties.


ABSTRACT Chirality induces structural frustration in liquid crystal systems, producing various kinds of chiral frustrated phases, for example, twist grain boundary (TGB) phases, blue phases (BPs) and dark conglomerate (DC) phases. Almost all molecules exhibiting these frustrated phases have a rigid shape. Especially, a bent–core unit is regarded as a key structure for BPs and DC phases. This paper describes that some flexible liquid crystal oligomers being far from a rigid bent–core molecule stabilise these phases. The LC oligomers have a supermolecular structure in which mesogenic units are connected via flexible spacers. By designing intermolecular interactions, they can exhibit various molecular packing structures in the liquid-crystalline phases as follows: chiral dimers inducing TGB phases, U-shaped and T-shaped oligomers stabilising BPs and achiral liquid crystal trimers exhibiting DC phases. I discuss how the designed liquid crystal oligomers produce the chiral frustrated phases. GRAPHICAL ABSTRACT


: The present article is embedded in the theme of modern dance and its influences in considering the reverberations of the works of Isadora Duncan and Edward Gordon Craig addressed in three kinetic images: the dance and the theater of the future; the Übermarionnette and its possible unfoldings and the Scene Project, the body and the space. To develop this reflection, the Foucauldian notions of image and displacement were used. It is concluded that there are no signs of exhaustion of the potency of the creative process of this two artists.


Objective:To evaluate the clinical value of ultrasound imaging in the diagnosis of post-menopause vaginal bleeding.Methods:Totally 98 patients who had post-menopause vaginal bleeding underwent ultrasonograph.The images were confirmed with pathology.Results:The coincidence rate of Ultrasound and pathological of endometrial carcinomawas was highest(17/18,94.4%),the coincidence rate of endometritis was lowest(3/13,23.1%),the coincidence rate of endometrium simple hyperplasia was 93.3%(28/30),the coincidence rate of endometrial polyps was 66.7%(8/12),the coincidence rate of atrophic endometrium was 92%(23/25).Conclusinon:Ultrasonography can preliminary identify the nature of endometrial lesions,can be used as a screening method for post-menopausal vaginal bleeding were treated with curettage before.


In the search for computational models that help to understand the dynamics of Complex Systems, one can take a great advantage from the impressive acceleration of computer tools and techniques. In fact the very structure of computation on digital computers has inspired the introduction of new class of models (algorithms), where interaction among degrees of freedom are expressed by logical rules acting over a discrete state space – something much closer to "biological language" than to standard (floating point) physical models. Starting from the definitions of spin systems, with little changes we reach a definition a new model that is well suited to describe different simulation systems. Such class of models is can be considered a subclass of the Agent-Based systems in vogue nowadays. Moreover, we shortly describe two microscopic simulators of this type, which are being used to study microscopic phenomena in two completely different fields of application, namely immunology and finance. As a final remark, given the lattice representation of space, such computational-modeling paradigm is well suited for efficient and "relatively simple" parallelization. Indeed, both models have been implemented to run on parallel computers adopting the Message Passing paradigm for Distributed Memory machines.


The performance of CoCrPt–SiO2 perpendicular recording media, which incorporate synthetic nucleation layers for inducing grain size control, was evaluated with regard to the crystallographic, microstructural, magnetic, interfacial, and recording properties. The media structure consisted of a 14 nm thick CoCrPt–SiO2 recording layer sputtered on two stacked Ru intermediate layers. When a submonolayer thick synthetic nucleation layer was inserted between the two Ru intermediate layers, the grain size and grain size dispersion were significantly reduced in both the upper Ru layer and the recording layer. An average grain size of 5.8 nm with 20% dispersion was achieved for the recording layer. The crystallographic growth of the Co (00·2) perpendicular texture remained unaffected with the Δθ50 at ∼4.4°; the coercivity was ∼2800 Oe and the coercivity squareness was ∼0.6. The roughness of the interface between the synthetic nucleation layer and the upper Ru intermediate layer did not significantly change, and the...


Myringotomy vs. 3.45 1.69 2.04 <.05 Non-myringotomy Bromhexine hydrochloride ('Bisolvon'), an oral mucolytic agent derived synthetically from the alkaloid vasicine, has been found to reduce the viscosity of mucous secretions in chronic chest diseases (Arch, 1963; Bruce and Kumar, 1968; Burgi, 1964, 1965; Harris, 1970; Matts, 1969), This action is due to an alteration in the structure of acid mucopolysaccharide fibres (AMPS), which are thought to be responsible for the viscosity of such secretions (Bruce and Kumar, 1968; Burgi, 1965), Acid mucopolysaccharide fibres are present in the normally viscid mucous secretions found in chronic secretory otitis media (Sade, 1966). Bromhexine has been used in an attempt to reduce the viscosity of these secretions, in order to encourage drainage and permit normal ventilation of the middle ear cleft. Results


Abstract The subject of the article is the creative activity of fan communities (fandom), with particular emphasis on the transmedia storytelling – stories presented simultaneously by means of various media. The development of the Internet in the Web 2.0 formula opened up a number of possibilities for the creation of fandoms focused on specific TV series, films, books or video games. The main manifestations of the activity of these groups can be boiled down, on the one hand, to analysing and commenting on a given cultural text, and on the other hand, to developing it by adding new stories, often using a different medium than the one originally used.


It is tried in this study to solve the major failures of island-acting based CMMS systems and high dependency to receiving maintenance operative information in equipment functional calendars through creating a one-way link from PLC monitoring computer with server software of CMMSwith the lowest cost and finally, its effects on defects caused by the mentioned faults would be analyzed.The sample context is Kerman's oil warehouse project. Desk study has been used and the information recorded in CMMS software has been utilized as resources for collecting statistical information to analyze efficiency of the practical activities performed. After examining normalization of the tests distribution using Kolmogorov–Smirnov test, analyzing the data using two dependent samples average comparison test (paired t-test) was conducted through SPSS software for each of the surveying components in situations of before and after the executive process. The findings indicate that creating a link between PLC and CMMS in addition to continuous update of the equipment function calendar concomitant with receiving constants feedbacks from PLC system reduce the available equipping time by decreasing the failures and considerably increase access to the repair personnel and also heighten the capability ofbetter managing periodic services consumables.


THE frontal sinus is an infrequent site of tumour metastasis. The most recent survey of the world literature (Bernstein, Montgomery and Balogh, 1966) reviewed eighty-two cases of metastatic tumours to the maxilla, nose and paranasal sinuses. Twelve of these, mostly renal in origin, involved the frontal sinus. The authors noted eight cases of metastatic carcinoma of the breast, seven to the maxilla and one to the nose. Metastatic carcinoma of the breast occurring in the frontal sinus has not been previously reported.


In this paper, we have investigated large scale disturbance in barotropic atmosphere on a sphere. It demonstrates that: considering nonlinear effects of interaction between waves in barotropic vorticity equation, the wave packet of the disturbance is governed by the famous equation-nonlinear Schrodinger equation. For the solitary wave, two factors are very important: one is spherical effect of the disturbance and the other is meridional shear of blocking high. In comparison with the results of local Cartesian coordinates, the former factor is the individuality of spherical soliton.


IntroductionThepreference of natural landscapes is important for landscape planning from the view point of tourism. The purpose of this study is to clarify the differences of scenery recognition of Japan and Indonesia, and to find the characteristics of scenery elements that are highly valued. Study The study was conducted with the following four steps: 1) after collecting the scenery photos of natural landscape from Indonesia (33 photos) and Japan (35 photos) of w a t e rf a ll , f o r e s t , s eac o a s t , r i v e r , w e tl a nd , m oun t a i n , and l a k e which the total of 68 photos, 2) these photos were categorized in groups by 105 university students and each group was labeled with a name, 3) the same students evaluated the photos according to favorability (5-scale) and exoticism (3-scale). The respondents from Japan were 55 students at Chiba University, and from Indonesia were 50 students at Bogor Agricultural University. Cluster analysis (Ward's method, squared Euclidean distance) was applied for the analysis of photo categories, and Mann-Whitney U Test was applied for the analysis of evaluation variances. a i n i n d i s t a n t v i e w . The f o r e s t was categorized by Indonesian, but Japanese categorized it as f o r e s t a nd m oun t a i n i n d i s t a n t v i e w . Japanese saw the forest from the bottom, so they could see the shape of the mountain which consists of forest. Japanese also differs the wetland as w e tl a nd i nd i s t a n t v i e w and w e tl a nd i n c l o s e upv i e w . From the distant view, Japanese only could see the grassland as main view, but from the close up view they could see the detail of landscape element such as forest nearby the wetland. As for the results of preferences evaluation, statistically significant differences were detected with 25 photos, 17 were from Japan and 8 were from Indonesia. On the other hand, exoticism evaluation detected statistically significant differences with 48 photos, 28 were from Japan and 20 were from Indonesia. Preferences evaluation between Japanese and Indonesian were also quite similar. Neither Japanese nor Indonesian recognized preferences with sceneries of f o r e s t and w e tl a nd . However, either the Japanese or Indonesian prefer w a t e rf a ll and s eac o a s t than others. Japanese and Indonesian like prefer natural landscape with water element than without it. While, based on exoticism evaluation, r i v e r and w e tl a nd were not recognized by both of countries, but c o a s t and w a t e rf a ll were recognized by both of countries. It is inferred that water element in landscape have an important role in scenic beauty. River and wetland in this photos have no landscape element diversity in it. Both of countries share commonality in scenery evaluations of preferences and exoticism, but differences have been also found in recognition based on the viewing point.


Abstract Background Influenza vaccination may reduce illness severity among those with influenza; however, data are limited. We determined whether outcomes were less severe among vaccinated compared with unvaccinated adults hospitalized with influenza over 5 seasons. Methods We included adults (≥18 years) hospitalized with laboratory-confirmed influenza during seasons 2013–2014 through 2017–2018 and identified through the US Influenza Hospitalization Surveillance Network (FluSurv-NET). Vaccination status was obtained through medical records, vaccine registries, and interviews. We excluded patients who were institutionalized, did not receive antivirals, or had unknown vaccine status or vaccine receipt <14 days before positive influenza test. We used inverse propensity score weighting to balance differences between vaccinated and unvaccinated groups and multivariable logistic and competing risk regression to evaluate the association between vaccination and outcomes including pneumonia, intensive care unit (ICU) admission, mechanical ventilation (MV), death, and ICU and hospital length of stay (LOS) in days. Models were adjusted for season and admission timing in relation to timing of antiviral treatment, symptom onset and season peak. Results Among 67,452 adults hospitalized with influenza, 43,608 were included; 47% were 18–64 years (38% vaccinated) and 53% were ≥65 years (65% vaccinated). Among patients with influenza A(H1N1)pdm09, vaccination was associated with decreased odds of ICU admission (odds ratio (OR) 0.81; OR 0.72) and MV (OR 0.66; OR 0.54) in adults 18–64 and ≥65 years, respectively; decreased odds of pneumonia (OR 0.83), death (OR 0.64) and shortened ICU LOS (relative hazard (RH) 0.82) in adults 18–64 years; and shortened hospital LOS (RH 0.91) in adults ≥65 years (figure). Vaccination was not associated with attenuation of severe outcomes in patients with influenza A(H3N2) and B. Conclusion Vaccination was associated with reduced odds of severe outcomes, including death, by up to 36% in adults hospitalized with influenza A(H1N1)pdm09. All adults without contraindications should receive annual influenza vaccination as there is evidence that it can improve outcomes among those who develop influenza despite vaccination. Disclosures All Authors: No reported Disclosures.


BACKGROUND: Hearing loss is the most prevalent human genetic sensorineural defect. Mutations in the CLDN14 gene, encoding the tight junction claudin 14 protein expressed in the inner ear, have been shown to cause non-syndromic recessive hearing loss DFNB29. AIM: We describe a Moroccan SF7 family with non-syndromic hearing loss. We performed linkage analysis in this family and sequencing to identify the mutation causing deafness. MATERIALS AND METHODS: Genetic linkage analysis, suggested the involvement of CLDN14 and KCNE1 gene in deafness in this family. Mutation screening was performed using direct sequencing of the CLDN14 and KCNE1 coding exon gene. RESULTS: Our results show the presence of c.11C>T mutation in the CLDN14 gene. Transmission analysis of this mutation in the family showed that the three affected individuals are homozygous, whereas parents and three healthy individuals are heterozygous. This mutation induces a substitution of threonine to methionine at position 4. CONCLUSION: These data show that CLDN14 gene can be i mplicated in the development of hearing loss in SF7 family; however, the pathogenicity of c.11C>T mutation remains to be determined.


Breast cancer susceptibility gene 1( BRCA1) is mutated in approximately 40%~50% of familial breast cancers and more than 80% of inherited breast and ovarian cancers. There are two repeats of BRCA1 C terminal domain at its C temimus(BRCT1 and BRCT2) that is required for its function in both transcriptional activation and DNA repair. Many cancer predisposing mutations are located in the BRCT domains, which have been shown to induce chromatin unfolding by use of an approach that allows visualization of large scale chromatin structure through lac repressor/lac operator recognition. To map the important region of BRCT2 domain (amino acid residues 1756—1852), six deletion mutant constructs were made. The chromatin structure assay showed that amino acid residues 1756—1808 are involved in the induction of chromatin unfolding. To further localize the critical amino acid residues, six alanine scanning mutant constructs were made. The chromatin structure assay demonstrated that the 1784VQLCG1788 region is critical for the chromatin unfolding activity. Mapping of the BRCT2 domain may aid in the presymptomatic risk assessment and provide a valuable tool for further study on the BRCT1 structure and function.


We present an algorithm that covers any given rational ruled surface with two rational parametrizations. In addition, we present an algorithm that transforms any rational surface parametrization into a new rational surface parametrization without affine base points and such that the degree of the corresponding maps is preserved.


We consider the pair correlation functions of both the order parameter field and its square for phase ordering in the $O(n)$ model with nonconserved order parameter, in spatial dimension $2\le d\le 3$ and spin dimension $1\le n\le d$. We calculate, in the scaling limit, the exact short-distance singularities of these correlation functions and compare these predictions to numerical simulations. Our results suggest that the scaling hypothesis does not hold for the $d=2$ $O(2)$ model. Figures (23) are available on request - email email@example.com


Despite 100 years after the discovery of thyroxine, controversy still exists regarding optimal thyroid hormone replacement therapy. Several anecdotal reports suggest that thyroxine alone therapy does not normalise psychological wellbeing. My cross-sectional study (n=1922) provided the first evidence in support of the hypothesis that a small proportion of patients on thyroxine alone therapy have increased psychological morbidity despite having normal TSH (publication 1). My second study was the largest randomised placebo controlled study to date to compare the effects of thyroxine alone and combined T3/T4 therapy over a 12 months period. This categorically proved that thyroxine alone therapy should be the first choice for hypothyroid patients (publication 2). Further genetic analysis of the deiodinase genes showed that a sub-group of hypothyroid patients with an SNP on D2 gene do have reduced psychological wellbeing on thyroxine alone therapy and improve on combined T3/T4 therapy compared to those without (publication 5). Both these findings were shown only by our study and were possible because of the large size (n=700). Detailed analysis of the various thyroid hormones and their ratio from our study showed that in addition to TSH, free T4 should be taken into account when treating hypothyroid patients (publication 4). My pharmacokinetic study provided the crucial and first evidence of the profiles of thyroid hormones on once a day combined T3/T4 therapy, highlighting the need to use either slow-release T3 or multiple doses of T3 in a day (publication 3). Our invited commentary and review (publications 6-8 & 10) have highlighted the importance of "individualised set points" for thyroid hormones, the complexity of thyroid hormone transport and actions as well as an algorithm for approaching hypothyroid patients. My other work (publication 9) was the first to test the possibility and provided the first evidence of deiodinase gene polymorphisms affecting circulating thyroid hormone levels and their possible role in psychological wellbeing in normal population. Thus, my work in the area, "Psychological wellbeing in patients of thyroid hormone replacement therapy" has provided several landmark findings, resulting in 10 publications including 4 in JCEM, 2 in Lancet and 1 in Clinical Endocrinology.


—Battery consumption is a general problem in any portable wireless device and it depends directly on the transmission technology (cellular, Wi-Fi or short-range wireless networks) that is used to send and receive data. When various networks are available, mobile devices should be able to choose which network interface to use based on a variety of factors, such as required bandwidth or energy efficiency. This work proposes a dynamic wireless network interface-selection mechanism focused on minimizing the energy consumption of the mobile device, allowing an increase in battery life. In doing so, Machine Learning (ML) regression-based algorithms are used to predict the energy cost per transferred byte for each type of available network interface using field data. A comparison of the energy consumptions for both the proposed mechanism and the Android native method is performed. Numerical results show that our proposal helps save energy.


The aim of this essay was to examine the circumventive logic of subjection in Charlotte Bronte's Jane Eyre. The Victorian classical novel has...


Objective To investigate the clinical effect of urokinase combined with thoracic drainage in the treatment of encapsulated tuberculous pleural effusion.Methods Patients with encapsulated tuberculous pleural effusion treated from Feb.2007 to Feb.2011 were randomly divided into experimental group(n=67) and control group(n=60).The patients in experimental group were treated with the combination of urokinase and closed thoracic drainage,while patients in control group were treated with closed thoracic drainage only.Results Better clinical effect was obtained in experimental group than control group(P0.05).Albumin level and WBC count were lower in experimental group than control group(P0.05).There were significant differences in pleural effusion disappeared time,length of hospital stay and pleural thickness between the two groups(all P0.05).Conclusion Urokinase combined with closed thoracic drainage for the treatment of encapsulated tuberculous pleural effusion can effectively improve the prognosis of patients.


Dear Sir,

The article by Gregory S. Antonarakis and Stavros Kiliaridis published in the December 2015 issue of EJO engaged our interest (1). We read the article with great avidity, as appropriate case selection is pivotal in determining the outcome of functional appliance therapy. The study evaluated the effects of masseter muscle thickness and maximal molar bite force on Class II functional appliance treatment and concluded that patients with thinner muscles and reduced bite force …


Redesigned Mental Health Clinical Documentation: Notification of Availability , Policy Directive PD2005_358 specifies the mandatory implementation of standardised mental health clinical documentation within public mental health services. The purpose of this Information Bulletin is to notify mental health staff of the availability of redesigned mental health clinical documentation. The modules have been redesigned in response to the comprehensive evaluation undertaken during 2006/07, with the redesign overseen and endorsed by the Mental Health Programs Council. The modules are available for order from Salmat from September 10, 2008


Measurements of the aircraft (10) instantaneous position and speed are included in co-operation messages regularly broadcast by radio to other aircraft (10'). The device wherewith the aircraft, operating in visual flight, is equipped, analyses the data contained in the co-operation messages which it receives from other aircraft and its own trajectory to identify possible risks of collision. Said possible risks of collision are signalled to the pilot, advantageously in voice form, in the messages identifying the direction wherein the other aircraft is visible and estimate of the time lapse remaining until possible collision occurs.


We analyse di erent types of embedded recovery techniques for primary and secondary nite element eld variables in applications involving viscoelastic ows. For the primary stress variables of an Oldroyd-B model, a direct/local averaging method and a patch recovery technique are compared. For velocity gradient recovery, local direct methods are compared to Galerkin least squares methods. Superconvergence properties are intrinsic to the methodology. Flow problems addressed include a sink ow, a start-up channel ow and a ow past a sphere. Such benchmark ows are employed e ectively to identify the properties of these various recovery techniques. We examine their comparative in uence upon accuracy and stability of a semi-implicit Taylor-Galerkin/pressure correction scheme.


Long-object problem and short-object problem both deal with reconstruction problems with truncated conebeam CT projections acquired with a helical path. They have significantly less practical limitations than original exact cone-beam CT reconstruction algorithms which the cone-beam must cover the whole object. The short-object problem can be defined as reconstruction of the whole object having a finite support in the axial direction with helical scan extends a little bit above and below the object's support. However the longobject problem is to reconstruct the central region of interest (ROI) of a long object having an infinite support in the axial direction with helical scan extends a little a bit above and below the ROI. Although the short-object problem is more difficult to solve than the conventional exact reconstruction with non-truncated projections, the long-object problem presents greater challenge to researchers. Recently, with the great development of panel detector technology and computer technology, more and more researchers have been inspired to work on it. Because of great practical value of long-object algorithms, this paper focuses on the review and discussion of recent developments in long-object algorithms. All Long-object algorithms are classified as exact and approximate algorithms. After going briefly over the history of cone-beam algorithms, some novel cone-beam long-object algorithms are introduced, such as: Tam's algorithm, PImethod, PHI-method, etc. Then, the methods described are being compared and discussed.


We construct first- and second-order time discretization schemes for the Cahn–Hilliard–Navier–Stokes system based on the multiple scalar auxiliary variables (MSAV) approach for gradient systems and (rotational) pressure-correction for Navier–Stokes equations. These schemes are linear, fully decoupled, unconditionally energy stable, and only require solving a sequence of elliptic equations with constant coefficients at each time step. We carry out a rigorous error analysis for the first-order scheme, establishing optimal convergence rate for all relevant functions in different norms. We also provide numerical experiments to verify our theoretical results.


THE first experiments with regard to vitamin C and tuberculosis were carried out on guinea-pigs. As far back as 1924, Prausnitz and Schilfl showed that guinea-pigs with tuberculosis, if they were fed on a scurvy-producing diet, did not react to tuberculin in nearly as marked a degree as tuberculous guinea-pigs which were on a normal diet. The reactions caused by the tuberculin disappeared more quickly in scorbutic animals, and they had a less marked febrile reaction. Bieling2 also found this true, but, nevertheless,-discovered that when tuberculin was injected into guinea-pigs subcutaneously, those with scurvy died in greater numbers than ,those which had not scurvy. In 1933 McConkey and Smith3 fed 72 adult guinea-pigs on tuberculous sputum for periods from six weeks to four months. 37 animals were kept on a diet partially deficient in vitamin C. Of these, 26 developed ulcerative intestinal tuberculosis. The other 35 animals were supplemented by an adequate amount of vitamin C, and of these only 2 developed tuberculous ulceration of the intestine. This seems to prove that in guinea-pigs vitamin C may have a protective power against infection with the tubercle bacillus. Schrbeder,4 in 1935, investigated the requirement of vitamin C in 3 patients with tuberculosis, and reported that all needed more than the normal daily amount. Next, Heise and Martin5 studied the metabolism of vitamin C in tuberculosis in a series of 44 cases. Of these cases, 6 patients, of whom 5 were active advanced cases, only excreted 0 to 5 mg. vitamin C daily. The next group of 14 cases excreted 5 to 8 mg. daily, and of these, 9 were active and 5 inactive. Seven active patie4nts and 14 inactive comprised the third group, which excreted 8 to 14 mg., and the last group of 13 patients had 12 inactive and only 1 active. These patients excreted over 14 mg. daily. Heise and Martin also showed that a group of 14 inactive tuberculous patients, when given 4-oz. orange juice (55 mg.) daily, excreted within two weeks at least 16 mg. vitamin C daily. On the other hand, a group of 10 cases, of which 8 were active, did not give a response when fed with the 4 oz. orange juice. From these experiments Heise and Martin therefore concluded that although a normal person may only require from 15 to 20 mg. of vitamin C daily, tuberculous patients may require much more, and …


Wound healing is a complex, specific, physiological, and biological process. Wound healing progresses through a series of tightly regulated, cascades events that starts at a time of injury and continues till recovery. In wound healing, a dressing material plays a crucial role. That is why selection of dressing materials according to wound condition is of paramount importance. Otherwise, acute wound may convert into chronic wound and thus, the normal function of wound healing cycle would get disturbed. This article has summarized information about various types of wounds, phases of wound healing, and wound dressing materials. In addition, it has also highlighted the role of nanotechnology in fabricating improved wound care products.


The restoration of rotational motion blurred images with the boundaries of non zero gray values is a study hotshot in the field of image processing. In order to quickly fetch the gray values of pixels along the blurring paths in the case of discreteness, the idea of Bresenham algorithm is incorporated into the process of restoration of rotational motion blurred image. The restoration algorithm based on deconvolution along the blurring path by mean of filtering in frequency domain is proposed. Meanwhile, in order to effectively restore the information of pixels in the boundary area, the less cost restoration algorithm based on knowledge guide is also proposed?Thus, the restoration of the blurred image with non zero boundary consists of two stages, in which the two proposed restoration algorithms are employed. On the other hand, the iterative calculation and complicated time consuming operations are avoided to speed up the image restoration. The effect of the proposed algorithms is validated by comparison experiments and a lot of test experiments in the microcomputer, and experimental results illustrate that the proposed algorithms are efficient and capable of resisting noise.


The effects of Mentha longifolia crude ethanolic extract (F 1), rich in luteolin glycosides (F 2), apigenin glycosides (F 3) and phenolic acids (F 4), were studied on CCl 4 -induced liver injury in mice. Administration of CCl 4 -induced significant impairment in hepatic antioxidant status, decreasing the glutathione content and superoxide dismutase activity, and stimulating lipid peroxidation. Pretreatment with Mentha longifolia extracts significantly improved hepatic antioxidant status in mice, which was most pronounced in the reduction of CCl 4 -mediated lipid peroxidation. In addition, in pretreated animals, an increase in hepatic glutathione and superoxide dismutase activity, as well as a decrease of cytochrome P450, was found.


Weaning piglets in pork production is a critical transitional stage due to, new handling, environment adaptation and dietary changes, which can affect feed consumption, hence to ensure proper food intake flavoring additives are normally used. The aim of the present trial was to evaluate the effect of adding four levels of flavoring agent solution (Stevia) in drinking water on newly weaned piglet productivity. Under a completely randomized design using 120 piglets under commercial production conditions, with two repetitions (15 piglets each) per treatment, were used to evaluate four levels on a flavoring agent in water (0, 0.5, 1.0, and 1.5 milliliter /liter). Increasing the levels of a flavoring additive augmented the final weight from 7.75 to 8.03 for 1.5 milliliters (P 0.05), but the feed to gain ratio was reduced (P 0.05), pero la conversion de alimento se redujo (P < 0.05). Concluyendo que usar saborizante tiene efectos positivos en ganancia y conversion. Palabras clave—Cerdos, destete, consumo de agua, saborizante estevia.


According to the discussion on key issues and the scopes of landscape ecology during the 16 th IALE-US annual conference in 2001, 6 key issues and 10 leading topics were explained, which synthesized the opinions on theory and methodology of 16 internationally famed landscape ecologists. The 6 key issues dealt with: (1) interdisciplinarity or transdisciplinarity, with researchers from different fields, planners, managers, social scientists and decision makers working closely together on ecological issues at the scale of landscape; (2) integration between basic research and applications, following the reciprocal, that research guides for applications and applications give feedback to research; (3) conceptual and theoretical developments, to incorporate the rapidly developing science of complexity (such as nonlinear dynamics, hierarchy, and self organization); (4) education and training for students and professionals with different interests and backgrounds; (5) international scholarly communication and collaborations, through regional and international conferences, scholar exchanges and cooperative projects; and (6) a reach out and communication with the public and with decision makers, supported by information technology and Internet. ;The top 10 topics included: (1) Ecological flow in land mosaics, including materials (organisms), energy and information flow across landscape mosaics; (2) Consequences, processes and scenarios of landuse/landcover change, in combination with economic geography and resource-economy; (3) non-linear dynamics and landscape complexity, with methods and concepts like self-organization, complex adaptive systems, nonlinear dynamics, phase transition, and metastability; (4) scaling, up or down across heterogeneous landscapes; (5) development of methodology, from spatial sampling, pseudo repetition and auto-correlation to ecological modeling; (6) the relationship between landscape metrics and ecological processes; (7) integration of human activity and landscape ecology, which is increasingly prominent theoretically and practically; (8) optimization of landscape pattern, incorporated in land management and planning; (9) landscape conservation and sustainability, focusing on biodiversity and endangered landscapes; and (10) data sources and accuracy evaluation for the broad-scale patterns and processes involved in landscape ecological research. The authors also expressed preliminary ideas on the establishment of a theoretical frame for landscape ecology in China, covering: (1) the theory of spatial ecology focusing on the relationship between pattern and processes, (2) the theory of landscape construction focusing on ordered human activity, and (3) the theory of landscape planning focusing on the multi-value character of landscapes.


The invention provides a terminal and a screen interface display method. The terminal comprises a zooming unit and a processor, wherein the zooming unit is used for shrinking contents displayed on a screen interface of the terminal and displaying the contents at a first area in response to a received interface shrinkage instruction; and the processor is used for regulating the brightness of a second area generated in the formation process of the first area on the screen interface. According to the technical scheme of the invention, the power consumption of the terminal, in particular to a large-screen terminal, can be reduced, the size of the screen interface can be configured flexibly, the privacy of a user is protected, and the one-hand operation of the user is convenient.


During the third quarter of 2014 milk prices remained steady, at historically high levels, for Connecticut dairy farmers. The statistical uniform price averaged $25.34/cwt while the cost of production took a sharp increase in September to $37.50/cwt.


ABSTRACT Since 2006, many U.S. food and beverage companies have pledged to market healthier foods to children to help combat the childhood obesity epidemic. Despite this, companies' expenditures on online advertising have increased of late. To explore this seemingly contradictory situation, the authors conducted a content analysis of approximately 100 food and beverage brand websites, examining a multitude of online marketing practices across a variety of different products, as well as the relationship between marketing techniques and the nutritional profile of promoted foods. This is the first study to examine if nutrition varied by marketing technique. Few brands maintained child-oriented websites, but the brands that did have child-oriented websites included a large number of games promoting particularly obesogenic food products. Somewhat surprisingly, games with many brand identifiers were paired with slightly less obesogenic foods. These findings present a mixed picture of the threat posed by online child-oriented food marketing.


The formulation of the tread compound for speed rated radial passenger car tire was described.Based on the requirements for the properties and characteristics of tread compound,SBR1500/SBR1712/NR blend,carbon black N234,aromatic oil sulfenamide type accelerator and olefin resin were chosen.The test results of shop compounding and lab compounding showed that the better processibility of tread compound was obtained and the physical properties of vulcanizate met with the design requirements.The finished tire 185/70R14 with the test tread compound passed the endurace test and 220 km·h -1 speed performance test specified in national standard and Gemany ECE standard respectively.


A total of 12 litters of neonatal piglets were randomly divided into four groups,two groups with creep feed and the other two without as the controls.Under each feed system,one group was supplemented with lactic acid bacteria preparing in skimmed milk,and the other group with skimmed milk.At 7,14,21,24 and 35 days of age,one piglet every litter was slaughtered,and tissues of stomach bottom,duodenal intestine and jejunal intestine were collected for histological analysis.The results showed that lactic acid bacteria could increase the number of oxyntic cells in fundic gland of piglets after weaning(P0.01),while creep feed could increase oxyntic cell number before and after weaning (P0.05).However,lactic acid bacteria and creep feed did not affect the thickness of fundic gland.Lactic acid bacteria could increase the height of duodenal villi, but had no effect on jejunal villi.


The article studies the approaches toward assessing economic availability of foodstuffs in the North-West federal district, provides an estimation of average per capita consumption of foodstuffs by the population, as well as taking into account caloric value and balance of nutrients content. The article also analyses the impact of the population incomes change on the consumption of basic foodstuffs.


The present invention discloses a method of hydrolyzing bagasse was mixed with the raw material for producing ethanol fermentation of molasses. Comprising the steps of: (1) the material is milled bagasse, delignification; (2) the bagasse by enzymatic treatment of raw materials fed-batch manner; (3) bagasse hydrolyzate by 5 ~ 10% (V / V ) yeast inoculum seed liquid ratio, the initial fermentation of molasses was added and mixed after fermentation. The present invention bagasse feed fed-batch hydrolysis to increase the sugar concentration in the hydrolyzate, followed by hydrolysis liquid are mixed and a small amount of molasses fermentation, can be integrated to solve alone enzymatic hydrolyzate fermented bagasse ethanol concentration is too low, the individual requires the use of larger defects fermentation of molasses a cumbersome process and subsequent contamination; molasses while rich in nitrogen, phosphorus and other nutrients and vitamins, can also provide a basic nutrient source for the yeast fermentation, molasses and bagasse can achieve integrated feedstock use, help improve overall economic efficiency cane sugar prices, it has good application value.


Abstract In this paper we study H ∞ tracking problems with preview by output feedback for linear systems with impulsive effects and the sampled-observation on the finite and infinite time interval. We consider the problems that the reference signals are previewed in a fixed time interval and known a priori over a whole time interval, and present feedback control laws for the H ∞ tracking problems. Our theory can be also applied into the sampled-control system with the control input realized through a zero-order hold and the sampled-observation.


This research aimed at identifying the influence of active involvement on blended learning for Statistics course on the learning outcomes of Physics pre-service teacher. This research also attempted to depict the benefits and challenges during the implementation of blended learning in the higher education context, particularly the implementation of blended learning for Statistics course among Physics pre-service teachers. The sample of this research was the entire students of Physics education department who attended Statistics course in the Fifth semester. Based on the results of the research, the active involvement of Physics pre-service teachers during blended learning session on Statistics course contributes as much as 56.5%. While the correlation equation obtained was Y= 44.509 + 0.503 X. The average responses of blended learning given by the Physics preservice teacher on Statistics course was 81.5%. The implementation of blended learning for Statistics course improves the active involvement of Physics pre-service teachers.


As educators, christian religion education (CRE) teachers play an important role in improving the quality of education. In carrying out their duties they need to be equipped with adequate abilities and skills through mastery of professional competencies and pedagogical competencies so as to provide strong motivation in carrying out learning in school. The purpose of this study was to examine the effect of professional competence and pedagogical competence on the work motivation of CRE teachers. The method used is a survey with a quantitative approach, involving 255 respondents of CRE teachers as participants of teacher professional education (TPE) from all over Indonesia. Data collection uses a questionnaire with descriptive and inferential statistical data analysis techniques. The results of the study indicate that professional competence and pedagogical competence influence teacher motivation. The influence of professional competence on work motivation is 29.2%. The magnitude of the influence of pedagogic competence on work motivation is 45%. While the influence of professional competence and pedagogical competence on work motivation is 47%..


We study optimization design method that aims at the unit layout in automation design process for integrated circuit. We take one dimensional logic gate as a design exampleBy using neural networks and Hopfield neural unit model,we bulid energy function to seek the best value among all extremums with simulated annealing algorithm, to attain demand that the total length of all connect lines among various logic gates is the shortest,and to increase optimization degree of layout optimization design


In the fourth instalment of this series Sue Newman of Boogie Mites looks at music's capacity to inspire joy and the associated benefits


Language as a communication tool consisting of a symbol system, which is composed of the framework of social group relations, can also have an impact on the overall structure of cultural interaction. Art as one of the cultural activities in Bali, can not be separated from the use of the Balinese language as a medium of communication. In Balinese gamelan practices, the role of the Balinese language is very important. This can be seen from the activity of playing gamelan Gambang. Gamelan Gambang is one of the unique Balinese gamelan. In which there is the use of the Balinese language as a form of maintaining the Balinese language from generation to generation. The method used in this study uses descriptive qualitative research methods through data collection, observation, interviews, discography, and documentation. Through this method, it is known that the preservation of the Balinese language is carried out by using the Balinese language alus as verbal communication, introduction to prayers of praise, writing Gambang gending notation. Various terms in Balinese gamelan techniques that use Balinese, such as the terms kotekan, cecandetan, tetorekan and oncang-ocang, while in terms of the terms of the playing techniques of each Gambang instrument that uses Balinese, namely; noltol, nyelangkit, nyelat/nyelag, ngoncang and nyading.


We study the sample complexity of nondeterministically testable graph parameters and improve existing bounds on it by several orders of magnitude. The technique used would be also of independent interest. We also discuss the special case of weak nondeterministic testing for uniform hypergraphs of arbitrary order.


ABSTRACT The objective of this study is to assess the existence of gendered climate change adaptation practices of smallholder farmers in the Gamo Highlands of Ethiopia. We hypothesized that smallholders' adaptation practices are gendered because of land fragmentation and gendered division of labour. To explore this, we considered sustainable land management practices as a tool for sustainable adaptation and assessed the effect of land management practices deployed and land fragmentation on intra-household time allocation. The results indicate that although land fragmentation increased hours worked by men and women significantly, fragmentation increased the working hours of men more than women. Application of a larger number of sustainable land management practices increases the mean working hours of women, but leaves unaffected the working hours of men, implying that adaptation practices are gender-biased. Therefore, this study can guide land management decisions by pointing out that fragmentation results in long working hours and adaptation practices may disproportionately affect women.


This paper mainly addresses the reflections, observations and analysis of a scholar-activist, engrossed in challenging intractable international development issues, through the use of a Global Youth Work pedagogic approach. Using the main frameworks of Global Youth Work, scholar-activism, positionality/situatedness and decolonisation, this paper challenges the " missionary position " and " pornography of poverty " approach of some organisations both in the North and South, consciously or unconsciously working and collaborating towards the amelioration of the human condition. There are two main factors that influence my situatedness: the structural violence that can be generated by knowledge production and configuration from a universally configured orthodoxy in the Development Education/Global Cooperation field that now requires the reimagination of " epistemologies of the South " as responses, which are " credible and visible " (de Sousa Santos, 2014); the second essential stance is my immersion in practice as a scholar-activist who is not only captivated by the process of theoretical knowledge production, but also in heretic and counter-orthodoxy approaches to challenging and changing the world, in practice. The focus of the Agenda 2030 on " eradicating poverty in all its forms and dimensions " and the reason d'etre of Global Youth Work (Sallah, 2014) of provoking consciousness and taking action, therefore underpins this paper; especially in the promotion of sustainable development. The main focus and lenses through which I do this is the Global Hands project, set up as a charity in The Gambia and a social enterprise in the UK, by former students of De Montfort University in the UK, whose mission is to build capacity and operationalise the dual mandate of Global Youth Work: to provoke consciousness; and to support those affected to take action (Sallah, 2014). A range of Global Youth Work interventions and case studies have been used in this c ontext, such as developing Africa's first solar -powered taxi service; developing a self-sustaining intervention in its capacity building hub in The Gambia by Global Education actors from the UK with collaborators in The Gambia; running a number of public campaigns, for example, on the " backway" ("illegal " youth migration from sub-Saharan Africa to Europe via the Sahara desert).


The low effectiveness of zakat distribution nowaday is related to the lack of interest of the community to pay zakat through zakat institutions. This is indicated by collection and distribution of zakat which is less managed. This eventually leads to the purpose of zakat in welfare of society which is not achieved. Social marketing campaigns as one marketing element  can be used as an alternative in changing people's behavior in paying zakat through Amil Zakat Institution. This study was aimed to measure the impact of social marketing campaigns of zakat payment via Amil Zakat on the decision of  community in paying zakat through the Institute amil zakat. Method used in this research was quantitative descriptive. Data were analyzed using simple linear regression analysis with social marketing campaign variables as independent variable and decisions in pay zakat through amil institutions as the dependent variable.  Results showed that social marketing campaign had positive influence on the community's decision to pay zakat through Amil Zakat


This paper analyzes the development of production techniques for "4D"products based on full-digital aerial photography method,and presents the common used production flow currently.At the same time,it discusses the technique progress of production related aspects in different degree.


The fabrication of carbon nanohorns (CNHs) from a methane precursor with argon in an inductively coupled plasma was recently demonstrated with a high production rate of ∼20 g/h by Casteignau et al. [Plasma Chem. Plasma Process. 42, 465 (2022)]. The presence of a promotor gas such as hydrogen was found to be important for the growth of CNHs, but the mechanisms at play remain unclear. Here, we study the impact of different promotor gases by replacing hydrogen with nitrogen and helium at different promotor:precursor (Pm:Pr) ratios, X:CH4 = 0.3–0.7 (X = H2 or N2, Ar, and He), and global flow rates [Formula: see text] and 3.4 slpm. The nature of the promotor gas is shown to directly influence the morphology and the relative occurrence of CNHs, graphitic nanocapsules (GNCs), and graphene nanoflakes. Using quantitative transmission electron microscopy, we show that CNHs are favored by an X:CH4 = 0.5, preferably with X = He or N2. With a lower total flow rate (1.7 slpm) of N2, even larger production rates and higher selectivity toward CNHs are achieved. Optical emission spectroscopy was used to probe the plasma and to demonstrate that the nature promotor gas strongly modulates the C2 density and temperature profile of the plasma torch. It is shown that CNHs nucleation is favored by high C2 density at temperatures exceeding 3500 K localized at the exit-end of the nozzle, creating a reaction zone with extended isotherms. H2 favors CH4 dissociation and creates a high C2 density but cools the nucleation zone, which leads to structures with a strong graphitic character such as GNCs.


Pediatric Blood & Cancer (PBC) arose from a series of discussions during 2002 among individuals in leadership positions in the International Society of Paediatric Oncology (SIOP/Dr. Allen Craft), and the American Society of Pediatric Hematology/ Oncology (ASPHO/Dr. Beverly Lange) and subsequently with members of International Society of Pediatric Surgical Oncology (ISPSO), Histiocyte Society (HS), the publication committee for the societies (represented by Drs. Peter Newburger and Daniel Green). Dr. Giulio D'Angio, Editor-in-Chief of Medical & Pediatric Oncology (MPO) and I (at the time, Editor-in-Chief of the Journal of Pediatric Hematology/Oncology (JPHO) also contributed to the exchange of ideas. Rather than seeking incremental improvements in existing journals, we hoped to develop a new journal, sponsored by all four societies that would provide a comprehensive, high impact platform for clinical, translational and laboratory investigations in pediatric hematology, immunology, transplantation and oncology. Several of us commented on this process in editorials published at the time of PBC's inauguration [1–3]. The first edition of PBC was published in January 2004. Both the first and the second editions were the result of extraordinary efforts by a publication committee that included Drs. Beverly Lange, Alan Craft, Peter Newburger, and Daniel Green. Giulio D'Angio and manuscripts previously submitted to MPO were instrumental in composing these two first editions. This group reviewed manuscripts, made all the editorial decisions, carefully edited the papers and worked closely with the publisher, John Wiley & Sons, Inc. Along with these devoted colleagues and friends, I helped with the third issue in March 2004 and have continued since then as Editor-in-Chief in March 2004. This report is a follow-up of last year's status report [4] and serves as an update of some of PBC's milestones in its 5th year.


Modern embedded systems are ever present within our daily lives. Such devices remain vulnerable to Differential Power Analysis via side-channel attacks, which provide a powerful and flexible framework for exfiltrating valuable information. This work applies these principles with respect to determining properties of the underlying finite state machine dictating code execution on a STM32F030 microcontroller. A K-nearest neighbors classification model is used to determine the order of state transitions within the finite state machine with a maximum accuracy of 81% over 256 different classes. A second experiment was performed to evaluate the effect of dimensionality on the classification accuracy and found an ability to classify with an accuracy over 95% in classes with 32 elements and perfectly classify between only two classes. Results validate the need for protections against power-based side-channel attacks when sensitive information is handled by FSM-controlled components.


Natural disasters of large scale such as typhoon, heat waves and snow storm have recently been increased because of climate change according to global warming which is most likely caused by greenhouse gas in the atmosphere. Increase of greenhouse gases concentration has caused the augmentation of earth's surface temperature, which raised the frequency of incidences of extreme weather in northern hemisphere. In this paper, we present spatial analysis of future typhoon genesis based on IPCC AR5 RCP 8.5 scenario, which applied latest carbon dioxide concentration trend. For this analysis, we firstly calculated GPI using RCP 8.5 monthly data during 1982~2100. By spatially comparing the monthly averaged GPIs and typhoon genesis locations of 1982~2010, a probability density distribution(PDF) of the typhoon genesis was estimated. Then, we defined 0.05GPI, 0.1GPI and 0.15GPI based on the GPI ranges which are corresponding to probability densities of 0.05, 0.1 and 0.15, respectively. Based on the PDF-related GPIs, spatial distributions of probability on the typhoon genesis were estimated for the periods of 1982~2010, 2011~2040, 2041~2070 and 2071~2100. Also, we analyzed area density using historical genesis points and spatial distributions. As the results, Philippines' east area corresponding to region of latitude 10°~20° shows high typhoon genesis probability in future. Using this result, we expect to estimate the potential region of typhoon genesis in the future and to develop the genesis model.


Adam D. Smith,1 Jose P. Mestre,1,2,3,* and Brian H. Ross4,3 1Department of Physics, University of Illinois, Urbana, Illinois 61801, USA 2Department of Educational Psychology, University of Illinois, Urbana, Illinois 61820, USA 3Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, Illinois 61801, USA 4Department of Psychology, University of Illinois, Urbana, Illinois 61820, USA Received 25 March 2010; published 7 October 2010


From The Honeymooners to The Big Lebowski, from The Flintstones to Ed, bowling has rolled right down the middle of American culture like no sport--or even pastime--in the nation's postwar history. This entertaining, illustrated history illuminates the place that bowling holds in the heart of America, as well as its loftier antecedents and the high-kitsch status all things bowling have recently attained.


Purpose of review The pancreatic duct epithelium is remarkable for its capacity to secrete HCO3− ions at concentrations as high as 140 mmol/l. The properties of the key transporters involved in this process and the central role played by cystic fibrosis transmembrane conductance regulator (CFTR) are the main focus of this review. Recent findings The Cl−/HCO3− exchanger at the apical membrane of pancreatic duct cells is now known to be SLC26A6. The 1: 2 stoichiometry and electrogenicity of this exchanger enable it to contribute to the secretion of HCO3− at high concentrations. The apical CFTR channels also appear to have sufficient HCO3− permeability to contribute directly to HCO3− secretion. There is a strong possibility that the Ca2+-activated Cl− channels at the apical membrane are members of the bestrophin family which, like CFTR, are also permeable to HCO3−. More has been learned about the complex interactions between CFTR and other transporters within macromolecular complexes coordinated at the apical membrane by scaffolding proteins. Further details are also emerging of the protective paracrine roles of nucleotides, nucleosides, bile acids and trypsin in the regulation of ductal secretion. Summary Most of the key transporters involved in Cl− and HCO3− secretion have now been identified and characterized. Current research focuses on the molecular interactions between these transporters and the ways in which they are regulated by extracellular signals.


A discontinuous flow, a high content of oil in sludge at the exit of the clarifier, and a non-efficient operation are the most common problems in the clarification stage of the oil extraction process. To solve the previous problems, the mill Unipalma de Los Llanos S.A. installed a primary separator of circular section, with slow agitation, in which a study was performed to try different agitation speeds and levels of dilution of incoming liquor, in order to evaluate the effect that these variables have on the content of oil in the sludge at the exit of the separator and in the losses of oil in centrifuged sludges. A better distribution of the existing equipment was also performed at this stage. The following important results were obtained: oil content in sludges at the exit of the separator from 4 to 6% in volume, decrease of the sludges to be centrifuged from 11 to 8.5 m3/h, less operation time of the centrifuges and lower losses of oil in humid base in centrifuged sludges, an optimum equipment operation with 2.4 r.p.m. and dilution of the crude to be clarified of 1.2:1 (oil : water). A clarifier with slow agitation considerably reduces the content of oil in sludge and leads the process to a stable operation. Nevertheless, it does not significantly influence the loss of oil in centrifuged sludges; this is achieved with an adequate operation of the equipment subsequent to the clarifier, maintaining a uniform flow in the system.


Background:
 Administration of alteplase is the standard of care for eligible patients presenting with symptoms of acute ischemic stroke (AIS). Telemedicine is increasingly being used to deliver acute stroke care to patients without in-person access to stroke expertise. This study reviews the thrombolysis experience of the largest known teleneurology network spanning 39 states and distributed across a heterogeneous multihospital population throughout the nation.

 Methods:
 Data was abstracted from internal medical records systems and relevant medical records obtained from partner hospitals. A retrospective analysis on the prospectively maintained database of patients who have received alteplase was performed. Data was collected from December 1, 2015 to May 31, 2019. Outcome analysis was restricted to those patients with available complete discharge data.

 Results:
 The analysis revealed 8,399 patients as having received alteplase during the study period. Of these, 56.7% had discharge information available. The mean patient age was 68.5 years, with a mean age of 70.5 years for females and 66.5 years for males. The median initial NIHSS score was 7, with 31.2% of patients presenting with an initial NIHSS score ≤4, and 8.7% presenting with an initial NIHSS score ≥21. The transfer rate to another facility was 31.0%. There were 2,417 home discharges (48.2%), 1,057 acute rehabilitation discharges (21.1%), and 478 skilled nursing facility discharges (9.5%). There were 28 patients who left against medical advice (0.6%). The symptomatic hemorrhage rate in this population was 1.1% (92), and there were 234 patient deaths (4.7%).

 Conclusion:
 A large-scale teleneurology platform for the emergent treatment of patients presenting with AIS symptoms is both safe and feasible. Due to the heterogeneity of this patient and hospital population, higher level refinement of this analysis to include hyperacute metrics, transfer data, and more comprehensive clinical and functional outcomes is warranted.


This paper investigates the spatial change of rare vegetation cover of Gobustan, Azerbaijan. The Gobustan State National Park (Conservation Area) is a nationally important desert/semi-desert located west and south-west of Baku, Azerbaijan. In 2007 Gobustan was declared a UNESCO World Heritage Site considered being of "outstanding universal value" for the quality and density of its rock art engravings. The Study Area at Gobustan contains a wealth of historical and archaeological sites and is also known for its rare vegetation. This investigation includes monitoring of existing threats to rare vegetation (Global Climate Change, oil and gas exploration, overgrazing of winter and summer pastures by domestic sheep, goats and cattle, pollution, etc.) as well the processing of remote sensing data to produce "measured" vegetation indicators. This study has shown that oil and gas infrastructure, in an ecologically important semi-arid region, has a negative effect on species abundance and cover of vegetation. Rare vegetation classification within a buffer zone indicates: Plant cover has decreased in the buffer zone and is higher than the Sensitive Area. Bare ground has increased dramatically in the buffer zone whereas in the Sensitive Area it has decreased slightly.


The influence of chemistry and soaking temperature (maximal temperature of the continuous annealing) on the final properties of non-oriented electrical steels has been studied. With this objective two different studies have been performed. First the Mn, Ni and Cr content of a low loss electrical steel
composition has been modified. An intermediate content and a high content of each element has been added in order to study the influence of this components on the magnetic looses, grain size and texture. Secondly the influence of the soaking temperature on magnetic properties, grain size and oxidation in four grades of non-oriented electrical steels (Steel A, B, C and D) was studied.


Patrick White is the most prominent, literary guru of the Australian literary circle whose arrival marked the most important stage in the growth and development of Australian literature. To White, Art is both expression and communication. As communication, White's task in his novels is to convey the essence of his poetic vision, to make the individual see. With this in mind in each of his work there is a search for ultimate meaning, where a plain, awkward, ugly life acquires a rich escape into idealised selfhood, and the evolutionary development of his characters toward a "superman" state. White believes that, if the doors of perception were cleansed, everything would appear to man as it is, that is infinite and his artistic function is a matter of penetrating the hard shell of social habit until he exposes that peculiar vibration which makes each person what he is. Hence in White's novels reality is all inward and it concentrate on the elected characters realising their fullest potential and each elected character makes a further step towards becoming the super being. They are poet-seers, to convey splendor transcendence above human realities, gifted with a peculiar insight into the nature of reality, rescuing man from void of his culture, and involved in a process that enables them to affirm Divine essence of the human condition. It is necessary therefore for those who take the inward path not to forsake the world altogether, but to return to it with new insight into the hidden divinity. White affirms the life of spirit by hinting at the life's hollowness. His vision encompasses not merely the inevitability of suffering in man's experience but the possibility that suffering may be both exemplary and redemptive, for the individual who suffers and for all those involved and gracefully embracing it can build a stronger awareness and provide wisdom.


Educators are becoming increasingly aware of the importance of dealing with individual differences in children's learning abilities. Of special concern is the problem of finding the best match between children's individual learning styles and instructional procedures. It was the purpose of this research to study the match between sequence of instruction and specific learning abilities of educable mentally retarded adolescents. Several studies (Hamilton, 1964; Jacobs and Kulkarni, 1965; Levin and Baker, 1963; Maurer and Jacobs, 1966; Payne, Krathwohl, and Gordon, 1967; Roe, and Case, and Roe, 1962) have dealt with the relationship between sequencing of programed instruction and test performance. In general, these studies have revealed that with normal children and college students there seem to be few real differences in performance between groups of subjects who have been exposed to logical, systematic instructional sequences and subjects who have taken illogical, random, or scrambled sequences of instruction. Although the logical sequencing of programed instruction is intuitively more appealing to educators, there is little evidence that normal children learn more effectively under the ordered than the random sequence.