BRCA1 plays a key role in homologous recombination (HR) DNA repair. Accordingly, changes that downregulate BRCA1, including BRCA1 mutations and reduced BRCA1 transcription, due to promoter hypermethylation or loss of the BRCA1 transcriptional regulator CDK12, disrupt HR in multiple cancers. In addition, BRCA1 has also been implicated in the regulation of metabolism. Here, we showed that reducing BRCA1 expression, either by CDK12 or BRCA1 depletion, led to metabolic reprogramming of ovarian cancer cells, causing decreased mitochondrial respiration and reduced ATP levels. BRCA1 depletion drove this reprogramming by upregulating NNMT (nicotinamide N-methyltransferase). Notably, the metabolic alterations caused by BRCA1 depletion and NNMT upregulation sensitized ovarian cancer cells to agents that inhibit mitochondrial metabolism (VLX600 and tigecycline) and to agents that inhibit glucose import (WZB117). These observations suggest that inhibition of energy metabolism may be a potential strategy to selectively target BRCA1-deficient high-grade serous ovarian cancer (HGSOC), which is characterized by frequent BRCA1 loss and NNMT overexpression.


Interleukin 6 receptor antagonists are used for the treatment of severe chronic inflammatory diseases. Recently they have been proposed as a treatment for severe COVID-19 patients. However, there is scarce scientific evidence to support this, which is why it is necessary to generate scientific evidence and perform clinical trials to evaluate the appropriateness of this therapeutic strategy.


Sulfonic acid functionalized graphene oxide (GO-SO3H) was found to be superior for the production of furfural from xylan with 79% of furfural yield. GO-SO3H was successfully recycled after each reaction, and it shows its reusability without significant loss in catalytic activity. Presence of oxy-functional groups not only strengthen the –SO3H in GO-SO3H but also help to enhance the substrate sorption capacity, which was probably not allow to leached it out into the reaction medium.


In this paper, we propose a set of similarity metrics for manipulating collections of values occuring in XML documents.
 Following the data model presented in TAX algebra, we treat an XML element as a labeled ordered rooted tree. Consider that XML nodes can be either atomic, i.e, they may contain single values such as short character strings, date, etc, or complex, i.e., nested structures that contain other nodes, we propose two types of similarity metrics: MAVs, for atomic nodes and MCVs, for complex nodes. In the first case, we suggest the use of several application domain dependent metrics. In the second case, we define metrics for complex values that are structure dependent, and can be distinctly applied for it and collections of values. We also present experiments showing the effectiveness of our method.


The reactive nitrogen-carbon plasma generated by electron cyclotron resonance (ECR) microwave discharge of N2 gas and pulsed laser ablation of a graphite target was characterized spectroscopically by time-integrated and time-resolved optical emission spectroscopy with space resolution for a study of gas-phase reactions and molecular radical formation in the plasma. The plasma exhibits very high reactivity compared with the plasma generated solely by ECR discharge or by pulsed laser ablation and contains highly excited species originally present in the ambient gaseous environment and directly ablated from the target as well as formed as the products of gas-phase reactions occurring in the plasma. The space distribution and the time evolution of the plasma emission give an access to the gas-phase reactions for the formation of C2 and CN radicals, revealing that C2 radicals are formed mainly in the region near the target while CN radicals can be formed in a much larger region not only in the vicinity of the ...


The purpose of  this study is to determine the performance of public services in the Dinas Kependudukan dan Catatan Sipil Kota Jambi. This study uses the concept of  performance measurement with five indicators of  productivity, quality of  service, responsiveness, r esponsibility and accountability. These indica tors are used to measure  the efficiency and effectiveness of  services, quality of  service received by  the public. The method used in this research is quantitative method. The research location is determined by the method of  purposive, are determined by deliberate that the study was conducted in the Depar tment of P opulation and Civil Registry. Data  collection techniques used in this study include interviews, observations, and literature. Based on the research findings that the productivity of  public services in terms of  the ability of  officers and service performance can be summed been efficient with an average result value of 70% of  respondents said either. The quality of  service in terms of  satisfaction of  the performance of  services, timeliness of  service, comfortable environment and good infrastructure which is an average result of  41% while the measured responsiveness of service delivery performance , kedesiplinan, service procedur es and speed of  service. The final result that  stands out from the responsiveness can be judged good quality with an average of 51% of  good quality, the next responsibility is measured on the suitability of cost and fairness of  service delivery is good is seen from the average value of  responsibility is 45% and the accountability of  public service in the Department of  Popula-tion and Jambi City Civil Registry, is good  for 70% of  respondents  said that responsibility.


This thesis describes the experimental results of optical pumping studies made in some Type 1 GaAs/Al0.3Ga0.7As single quantum wells (QWs), ranging in widths from 50 to 200A. Optical pumping uses circularly polarised light to photocreate spin orientated carriers in the QWs. The polarised carriers, principally the electrons, transfer angular momentum to the nuclear spins of the lattice through the Fermi contact hyperfine interaction. The orientated nuclei act back on the electrons through the same interaction. Studies of the nuclear and carrier spin systems may be effected by monitoring the circular polarisation of the recombination luminescence. The Hanle Effect of the electron orientation within the QWs is measured as a function of well width, and of the non-photoexcited hole concentration. Correlation of this data with carrier recombination time measurements produces the magnitude of the carrier Lande factor. Allowing the nuclear field to influence the Hanle curves determines the sign of these g - factors, whence the free conduction electron value is observed to change sign at 55A and become positive for thinner wells. This result is compared to the bulk g -values of GaAs (-0.44) and Al0.3Ga0.7As (+0.40), and modelled using k . p theory to estimate the contributions to g* from the well and barrier materials. Nuclear orientation within the wells is observed by the optical detection of nuclear magnetic resonance (ODNMR), via the application of a radio frequency field (RF) to the orientated nuclear spins. ODNMR of ~ 1011 nuclear spins is measured in almost all the single QWs. The signals are studied as a function of various experimental influences, such as well width, p-type carrier concentration, RF magnitude, optical pumping time, and RF sweep rate. Observation is made of extrinsic lattice strain and spin diffusion of the nuclear magnetization, and results suggest increased nuclear relaxation rates within the barrier. n-type wells show no ODNMR, indicating that incomplete hole relaxation is present within the wells. The very wide and undisplaced Hanle curves observed in this type of well support this view. Nuclear orientation is not observed in some GaAs/InxGa1-xAs QW systems. This null result is discussed in terms of the experimental factors important for its successful observation in the GaAs/Al0.3Ga0.7As systems.


Background and objectives: Tuberculosis (TB) is a serious public health problem and a significant diagnostic and therapeutic challenge worldwide. Molecular diagnostic techniques are crucial parts of the World Health Organization's new tuberculosis control strategy. This study aims to identify Mycobacterium tuberculosis and rifampin resistance in pulmonary and extra-pulmonary clinical specimens using the Gene Xpert


A key objective in the follow-up of women with a history of breast cancer is the detection of local and distant disease at a curable stage. Regular dinical examination and yearly mammography are the standard of care. No consistent evidence supports annual chest radiography, bone scans; or tests of serum tumor markers. Order laboratory or diagnostic tests only if indicated by dinkal findings. Advise women to report new symptoms promptly rather than waiting for the next scheduled examination. Some evidence supports the use of venlafaxine for tamoxife-associated hot flashes. Despite the increased incidence of endometrial carcinoma in women taking tamoxifen, routine endometrial biopsies are not recommended. Most experts advise that women with a history of breast cancer who wish to have a child wait 2 to 3 years before becoming pregnant.


To address the complex optimization problem of antenna design for 5G wireless communication systems, we enhance the Teaching Learning Based Optimization (TLBO) algorithm with Opposition Based Learning (OBL). In this paper, we obtain new TLBO algorithms with different OBL variants. The different opposition schemes are evaluated to find the variant with the best performance. Numerical simulation results show that the current optimum opposition scheme outperforms the other algorithms and achieves the highest average ranking. Moreover, the COO-TLBO variant is applied in the design of aperture-coupled E-shaped patch antenna. Preliminary results demonstrate very satisfactory values of return loss in the desired frequencies of 5G wireless communication systems.


The invention relates to the field of tobacco processing, in particular to a method for preparing tobacco liquid by tobacco stem fiber microwave degradation and application. The method comprises a step (1) of drying, smashing and sieving tobacco stems; a step (2) of performing microwave heating in an ionic liquid atmosphere; a step (3) of filtering and collecting filtrate, performing reduced pressure distillation after organic solvent reverse extraction, and obtaining tobacco liquid. Novel thinking is provided for tobacco stem utilization, the tobacco liquid can be used for cigarette blending and can also serve as a coating base solution to produce reconstructed tobaccos, baking fragrance of cigarettes or the reconstructed tobaccos can be remarkably improved by adding the tobacco liquid, and the problems that the cigarettes and particularly the reconstructed tobaccos are thin in fragrance and woodiness smell is obvious are effectively solved.


When adjustment member drive means (6) adjust the vehicle in case of a computer-aided manner sandwiched identified object, the adjusting force (F) related to the measured value of the predetermined threshold value (FR) and compared, in when reaching the threshold, the adjusting movement causes slowing, stopping or reversing, it is determined and considered in the comparison of the hardness of the spring rate correction term to characterize an object, for correcting the adjusting force (F) with a threshold value (FR) in this case The relationship between.


As Black people struggled for freedom from oppression in the United States, toward the end of the modern era of the African American freedom struggle, a reflexive moment was taken to assess Christianity and its meaning for those whom Howard Thurman referred to as the "disinherited." This article attempts to take up the pattern of reflective thinking, which began with Howard Thurman, James Cone, and William R. Jones, extending the thought forward to its natural conclusions. In doing so, the author intimates that the concepts that lead to racism and racial aggression are bound within the signs, symbols, and frameworks of white American Christianity, which has become a secular religion or secular way to order society. These signs, symbols, and frameworks continue to do the work of setting the ground for each subsequent generation to demonstrate a similar racial attitude as the preceding one. They also set the groundwork for Black reflective thinkers to find necessary the development of a posture of rejection toward white American Secular Christianity and all its derivative forms.


A new type of thin and broadband metamaterial absorbers containing patterned magnetic sheet as the middle layer in the tri-layer structure are presented in this article. Those absorbers with more than 12 GHz absorption bandwidth which reflectivity is below −10 dB in the measured frequency 2–18 GHz were designed and experimentally realized by the thickness only in 1.8 mm. Design and experiment results display a huge expanded absorption bandwidth comparing to tri-layer absorber with complete sheet (not patterned sheet) as middle layer. By analysing the electric field distribution, it is found that the scattering effect caused by the patterned magnetic sheet plays a vital role in the feature of expanded bandwidth. Our results demonstrate that the great practicable method of broadening the absorption bandwidth and achieving lower total weight of thin magnetic absorber can be realized by the incorporation of patterned magnetic sheet.


An immunodiagnostic assay was developed for early detection of Phomopsis phaseoli, cause of pod and stem blight, and P. longicolla, cause of seed decay of soybeans (Glycine max), in asymptomatic soybean plant tissue using polyclonal antibodies developed against P. longicolla. Immunoblot analysis of the immunogen and cross-reactive fungal antigens showed a broad smear above 50 kDa. Analyses of P. longicalla and 17 other common soybean parasitic or saprophytic fungi resulted in strong reactions with all Phomopsis spp. and Colletotrichum truncatum (.)


Ringing artifacts that appear as spurious signal near sharp transitions in a signal appear as ghosts (or) near edges. Two techniques called LPF and ASLPF is used. LPF is used for only just identifying the artifacts present in the video image. ASLPF (Adaptive Spatial Low Pass Filter) is used to identify the artifacts whether it is present in horizontal (or) vertical position (or) near edges. DCT is applied to each and every pixel in the block; the spatial domain is converted into frequency domain. But now a technique called Adaptive Spatial Low Pass Filter (ASLPF) is used to identify the artifacts and remove it completely. Video is converted into frames and each frame is compressed for removing the artifacts. Finally the reduction of artifacts is shown in PSNR.


Stress is major problem in population especially in young adult students in the present environment. Stress adversely affects almost all the systems of the body including cardiovascular system predisposing the individual at higher risk for development of hypertension and other cardiovascular diseases. The present study was conducted to assess the effect of acute stress on cardiac output and systemic peripheral resistance in young adult medical students. One hundred asymptomatic healthy male medical students, aged 17–25 years, participated voluntarily in the present study. Cold pressor test (CPT) was used to produce acute stress. Subjects were exposed to acute stress by standard procedure of CPT, i.e. immersion of hand in cold water of 8°c for 2 minutes. Blood pressure and heart rate were recorded by using automatic digital sphygmomanometer. Cardiac output, peripheral resistance and other cardiovascular parameters were recorded using Impedance Cardiovasograph (Nivomon). All the parameters were recorded before and immediately after cold pressor test. Results showed that there was significant increase in all cardiovascular parameters after exposure to acute stress in form of cold stress. Increase in diastolic blood pressure (DBP), heart rate (HR), systemic peripheral resistance (SPR) and systemic vascular resistance index (SVRI) were highly significant (p<0.001). while increase in systolic blood pressure (SBP), cardiac output (CO), stroke volume (SV), cardiac index (CI), stroke volume index (SI) were less significant (p<0.05).


As the popularity of cloud computing is increasing there is an urgent requirement of developing highly efficient and highly qualitative cloud applications (CA). Hence, it be-comes a big research problem. A recommender system recommends the suitable item to the user and almost all the systems provide a rating score for preference. Traditionally, algorithms predicts the ratings that a user should give to the unrated components to queue the item in recommended list. To select an optimal candidate from a set of function-ally equivalent candidates is crucial through approaches that follow a framework for component quality ranking. More-over, such framework helps in detecting the poor performing candidates from a highly distributed cloud applications. In this paper a novel technique is proposed to provide personalized component ranking for designers by employing the past usage of components by different users. In this approach the similarity between the users is measured based on their rankings for functionally equivalent components set instead of their rating values. In this approach no additional invocation of cloud component is required. Experimental results on real world web-service invocations data set shows that the proposed approach outperforms the previous approaches.


We establish a method from an X‐ray observation of a galaxy cluster to measure the radial profile of the dark matter velocity dispersion, σDM, and to derive the dark matter "temperature" defined as μmp σDM2. The method is applied to the XMM‐Newton observation of Abell 1795. The ratio between the specific energy of the dark matter and that of the intra cluster medium (ICM), which can be denoted as βDM in analogy with βspec, is found to be less than unity everywhere ranging ∼ 0.3 – 0.8. In other words, the ICM temperature is higher than the dark matter "temperature", even in the central region where radiative cooling time is short and cooling flow phenomena is expected to be observed. A βDM value smaller than unity can be most naturally explained by heating of the ICM in addition to gravitational heating.


Current technological developments can bring changes in all sectors, such as in the education sector which can make it easier for an educator to transfer their knowledge through the media used in Arabic language learning. The process of transferring knowledge is usually done face-to-face, but because of these changes and developments, the process of delivering knowledge is done virtually through learning media. Wavepad as one of the media that can be accessed by educators to facilitate the learning process that can improve the skills of an educator through the media he developed. An educator can also develop a mindset through these media. The method used in this study is a qualitative method, which in this method is carried out by conducting interviews with these students and analyzing and collecting student data in MTS PSA difficult water. The indicator that can be successful from this research is to add insight to what is being studied in educational institutions. The results obtained from this research activity are that researchers can develop new insights and ideas, so that they can come up with creative ideas. The researcher also hopes that educators can take advantage of the wavepad application in Arabic language learning, especially for maharah istima 'which is liked by students, and students can be enthusiastic in participating in the learning process.


In this work we present a microscopic theory based on a cavity QED semiconductor model to investigate the emission of InGaAsP-based metallic cavity nanolasers. The consistent approach of modelling the interplay of quantum optical and semiconductor effects allows for excellent agreement with pump-power dependant experimental results.


While the postulates of Koch have never been fulfilled in granuloma inguinale, there is much presumptive evidence to indicate that Donovania granulomatis is the aetiological agent of the disease. The prototype of D. granulomatis was isolated originally by Anderson (1943), and since that time at least six other investigators (Beveridge, 1945; Dienst, 1948; Goldberg, Weaver, and Packer, 1953; Jennison, Helwig, and Milstone, 1947; Sheldon, Thebaut, Heyman, and Wall, 1945; Thomison, 1951) have isolated additional strains. The organism isolated in each of these cases was a Gram-negative pleomorphic rod which grew only in the presence of egg yolk material. Morphologically these organisms showed bipolar staining with Wright's stain and, when capsulated, closely resembled the Donovan bodies which are pathognomonic for the disease. In addition to the morphological similarity between Donovania and the Donovan body, serological data indicate that patients with granuloma inguinale have antibodies directed against the Donovania. Anderson, DeMonbreun, and Goodpasture (1945) were able to show that an antigen prepared from one of their strains of Donovania reacted with sera from patients with the disease. Goldberg, Weaver, Packer, and Simpson (1953) have shown by complement-fixation tests that 136 out of 151 sera from patients with granuloma inguinale gave positive reactions with antigens prepared from strains of Donovania. Only one of 112 of their control sera gave a positive reaction. The data also indicated that the titres of the sera increased with the duration of the disease. If we assume that D. granulomatis is the aetiological agent of granuloma inguinale, two pertinent questions must be answered: (1) What is the normal habitat of the organism? (2) How is it transmitted from patient to patient?


Inspiration from foreign urban sprawl studies has great value to China.Document-data method and qualitative method are used to summarize the concept and characteristics of urban sprawl.Experience of urban sprawl studies in foreign countries are summarized and assessed from several aspects: impact factors of urban sprawl,impact of urban sprawl on the environment,policies and instruments of urban sprawl control and study methods of urban sprawl.


Soil is a peculiar material. Some waste materials such Fly Ash, rice husk ash, pond ash may use to make the soil to be stable. Addition of such materials will increase the physical as well as chemical properties of the soil. Some expecting properties to be improved are CBR value, shear strength, liquidity index, plasticity index, unconfined compressive strength and bearing capacity etc. The objective of this study was to evaluate the effect of Fly Ash derived from combustion of sub-bituminous coal at electric power plants in stabilization of soft fine-grained red soils. California bearing ratio (CBR) and other strength property tests were conducted on soil. The soil is in range of plasticity, with plasticity indices ranging between 25 and 30. Tests were conducted on soils and soil-Fly Ash mixtures prepared at optimum water content of 9% .Addition of Fly Ash resulted in appreciable increases in the CBR of the soil. For water contents 9% wet of optimum, CBRs of the soils are found in varying percentage such that 3,5,6and 9.We will found optimum CBR value of the soil is 6%.Increment of CBR value is used to reduce the thickness of the pavement. And increasing the bearing capacity of soil.


This work applies public choice theory to perennial questions of constitutional law, legislative interpretation, and administrative law. It argues that in many cases public choice theory's reach has exceeded its grasp, but in others public choice insights have not been pursued far enough.


Following a report of superconductivity in nominally undoped T′ lanthanum cuprates which, if verified, will have wide‐ranging implications for the understanding of the mechanism of high‐temperature superconductivity, an attempt has been made to independently reproduce or otherwise elucidate the reported results. Utilising a different preparation technique from the original report, thin film samples of nominally undoped La3+ 1.85Y3+0.15CuO4 have been prepared by pulsed laser deposition in all three structural variations reported for the system, labeled T, T * and T′. The unique nature of pulsed laser deposition as a highly non‐equilibrium process has been exploited in the fabrication of the metastable T* and T′ phases, allowing a significant improvement in sample quality over that obtainable by the use of chemical pressure and epitaxial strain alone.


The paper presents an implementation and tests of a simple home entertainment distribution architecture (server + multiple clients) implemented using two conventional cabling architectures: CATV coaxial cable and conventional Ethernet. This architecture is created taking into account the "Home gateway" concept present in most attempts to solve the problem of the "Intelligent home". A short presentation of the experimental is given with an investigation of the main performances obtained using this architecture. The experiments revealed that this simple solution makes possible to have entertainment and data services with performances close to traditional data services in a cost-effective architecture


On-Ioad tap changer (OLTC), as a frequently operated part of transformer, is affected by both transient mechanical stress and electric stress, bringing high failure rates. The vibration signal is closely related to the mechanical state of the switch contact. Therefore, it is of great significance to monitor the contact state by analyzing the vibration signal. In this paper, the accelerometer is used to collect vibration signals during the switching operation of OLTC. The envelope of vibration signal is extracted by Hilbert transform. The region of sudden change is distinguished by singular value for each peak of envelope signal. The vibration signals generated by the action of the drive motor and switching process are divided into 5 similar parts according to the operation mode of OLTC. The time-frequency analysis images are obtained by using wavelet transform. The energy-mean of each part of the time-frequency analysis images are obtained. Comparing the energy-mean, it is found that the energy-mean of the 5 parts is similar. The results show that the mean-energy of the time frequency analysis image of the vibration signals of the drive motor and switching process can be used as the characteristic quantity, reflecting one the different changes of the vibration signals. Therefore, the mean-energy of the time-frequency analysis images of the vibration signals can be used for the mechanical state detection of the OLTC.


Objective:Through establishing and evaluating the indicator system of Chinese Wushu development,this paper tries to provide theoretical guidance for development and operational basis for the relevant departments.Method:By using the method of literature review, expert investigation and statistical analysis.Result:The authority participate modules is 100%and 84.8%in the first and the second Delphi consultation table,The authority modules is greater than 0.6,in which 50%is up to 0.7.For the 58 items,the averages of Severity Code is greater than 3.5 and the variation coefficients is below 0.30,which indicates that the concordant of the experts' opinions are perfect and the forecast result is desirable. Conclusion:4 one grade indicators,10 two grade indicators and 58 three grade indicators are proposed for the indicator system of the Chinese Wushu modernization and sustainable development. And the one grade indicators include modernization of Wushu industry,modernization of Wushu technology information,modernization of Wushu education and internationalization of Wushu.It can get the value of the comprehensive evaluation for Wushu modernization and sustainable development by creating the comprehensive evaluation formula,which will lead to the vertical and horizontal heterogeneity for Wushu.


Separator absorption is an important parameter in batteries of all chemistries. The ability of a separator to absorb, hold, and release electrolyte affects cell performance, particularly in areas of rate capability. To quantify separator absorption, a gravimetric absorbency tester was developed as a possible characterization tool. The absorptive characteristics of separators were tested in uncompressed and compressed states. Total mass absorption and absorption rate data were collected. Volume changes (under ambient and high-pressure environments) were also noted.


Actual nutrition of pupils in Altai Krai was studied. Decreased supply of proteins, fats, vitamins, mineral substances was revealed. Hygienic recommendations on improvement of nutrition of children and adolescents were given.


Sensor nodes are often deployed in large numbers to monitor extended sensor fields. In such scenarios data aggregation plays a crucial role on summarizing data forwarded to base stations in sensor networks. As sensor networks are commonly deployed in open and unattended areas, they are vulnerable to physical tampering as well as remote attacks. Existing security techniques focus primarily on methods used by an aggregator node to monitor and detect compromised behavior by nodes that report data to it. We propose a novel mechanism, combining techniques from statistics and artificial intelligence, by which nodes reporting to an aggregator node can monitor whether the latter is reporting incorrect aggregated values. In our framework, nodes are arranged in a hierarchy. We develop a reputation management scheme in which each child node keeps a reputation value of its parent. For each data reporting event, a node is privy only to the data value it reported and the aggregated value forwarded by its parent node. Each node then calculates the probability of the parent reporting correctly aggregated values over an epoch of events by adapting a statistical hypothesis testing scheme. This probability is used to incrementally update the trustworthiness of the parent node using a learning scheme. When the trustworthiness of a node falls below a threshold it can no longer be trusted with the aggregation task and should be reallocated or eliminated from the network. We evaluate the robustness of our adaptation of a couple of statistical hypothesis testing schemes and analyze their applicability for different types of malicious behaviors by compromised sensor nodes.


Our architecture for peer-to-peer Internet telephony using the Session Initiation Protocol (SIP) supports basic user registration and call setup as well as advanced services such as offline message delivery, voice/video mails and multi-party conferencing. In this paper, we describe the design and implementation of our P2P-SIP client adaptor, SIP PEER, using pseudo code and example messages. We also explain how to use existing SIP user agents such as X-lite and Cisco IP phone with SIPPEERto participate in P2P network.


To test and adopt the methodology of future PISA surveys in Computer Science, we have utilized the Bebras Contest as a test field. We performed latent trait analysis of the questions of the German Bebras contest 2009 to find sets of questions that might measure joint psychometric constructs (competencies). After having identified several sets, we have tested the fit of the mono-parametric Rasch Model and evaluated the distribution of person parameters.


Cross-correlation functions of ambient and shipping noise were measured by near-bottom hydrophones in 100 meter-deep water in the Straits of Florida. This paper is based on cross-correlations in the 20-100 Hz frequency band between two hydrophones 5 km apart. The propagation conditions between the hydrophones were nearly range-independent. The noise cross-correlation functions provides an approximation to the deterministic Green's functions, which describes sound propagation in opposite directions between the hydrophones. Using a background sound-speed profile, 44 eigenrays were found and relevant perturbation matrices were calculated for propagation with and against the flow. Modelled Green's function has 10 peaks, which have been matched to the peaks of the cross-correlation function. Sound speed and flow velocity profiles in water have been retrieved by minimizing the mismatch between positions of the modelled and measured peaks. Acoustic frequencies being low, errors in ray-theoretical modeling limit ...


Research has revealed one of the top factors contributing to driving HR best practice was effectively implementing a high level of transparency and open communication. Workforce magazine recently quoted HR communications specialist, Jennifer Benz, as saying: "A lot of companies still communicate like it's 2006". The certified Top Employers in Africa for 2017, however, have no such problem - coming in way ahead of the communications curve. A record number of 11 organisations made up of 83 certified operations achieved the coveted Top Employers Africa 2017 Certification. In order to be eligible for this title, participating organisations must be certified in a minimum of four African countries. The 11 Top Employers Africa 2017 are: AbbVie, Becton Dickinson, DHL Express, Dow, EY, G4S, Old Mutual, Orange, Philip Morris International, Unilever and Vodacom.


RFID provides real-time tracking, resulting in two additional benefits as an information technology. When inventory is inaccurate and real-time tracking is not available organizations have to use a periodic review policy. When inventory is accurate and realtime tracking is available, they may switch to a continuous review policy. Based on a case study in a radiology practice, we compare the operational and economic differences between a system that uses barcode technology and periodic review, and one that uses RFID technology and continuous review. While the first switch from barcode to RFID is a technology improvement providing automatic counting, the second switch from periodic to continuous review is a process innovation. We measure the value of automatic counting, process innovation, and the total of the two, (the value of RFID). We also explain how these benefits change with service level, lead time, demand, etc.


The invention relates to moisturecured one-component polyurethane paint and a preparation method thereof. The polyurethane paint comprises the following raw materials in percentage by weight: 10%-20% of polyisocyanate monomer, 20%-40% of polyether polylol, 5%-15% of plasticizer, 30%-50% of modified mineral powder, 1%-5% of latent curing agent, 0.1%-2% of environment-friendly catalyst covered with cyclodextrin, 0.1%-1% of defoamer and 0.1%-1% of mono-isocyanate compound, wherein the modified mineral powder is mineral powder of which the surface is covered with a covered agent by a chemical covering method; and the environment-friendly catalyst covered with the cyclodextrin is in a nanometer cavity of the cyclodextrin, and the cyclodextrin is unmodified cyclodextrin or modified cyclodextrin or the composition of the unmodified cyclodextrin and the modified cyclodextrin. The moisturecured polyurethane paint disclosed by the invention solves the problem in storage stability of a one-component polyurethane product, and the storage life of the moisturecured polyurethane paint can exceed one year.


The conventional two-stage structured power-supply units (PSUs) requiring the hold-up time operation have generally low efficiency dc/dc stage because it is difficult to be designed optimally. As a result, to improve the efficiency of the dc/dc stage, many hold-up time compensation methods have been presented. However, they cannot still optimize the dc/dc stage due to its bad influence on the design conditions. In addition, they can only be employed in certain dc/dc topologies as well as they still ill-affect the design conditions of the dc/dc stage. Therefore, in this paper, a new hold-up time compensation method is proposed to overcome the conventional limitation. Compared to the conventional method, since the proposed method delivers the output power by using not the dc/dc stage but the power factor correction (PFC) stage during the hold-up time, it can optimize the dc/dc stage at the nominal state without any bad influence, which enables the dc/dc stage achieve a high efficiency. Furthermore, it can be widely applied to various dc/dc stages. The validity of the proposed method is confirmed by experimental results from a prototype with 90-264Vrms input and 480W/10A output.


PURPOSE: A hydrogen sulfide eliminating apparatus equipped with rotary porous desulfurizing disks and a method for eliminating hydrogen sulfide using the same are provided to improve the efficiency of desulfurization and to secure the wide contact area of hydrogen sulfide and iron catalytic liquid. CONSTITUTION: A hydrogen sulfide eliminating apparatus equipped with rotary porous desulfurizing disks includes an iron catalytic liquid storing bath(8), a desulfurizing reactor(1), and a settling bath. The iron catalytic liquid storing bath stores iron catalytic liquid. The desulfurizing reactor includes rotary desulfurizing disks(2). The rotary desulfurizing disks contact the iron catalytic liquid with hydrogen sulfide containing gas to generate solid sulfur and to eliminate hydrogen sulfide. The setting bath settles the solid sulfur form the desulfurizing reactor.


With the rapid growth of economy and population in Hebei Province, energy consumption and greenhouse gas emissions have increased year by year, and environmental problems have become increasingly prominent. How to achieve rapid economic growth under the constraints of the environment is the Hebei provincial government to solve the problem. Based on the material, energy, value balance and input-output model, this paper builds a comprehensive dynamic simulation model of social economy, greenhouse gas emission and energy utilization. Introduction In recent years, rapid economic development in Hebei Province, the irrational phenomenon of industrial structure has become increasingly prominent, air quality problems continue to deteriorate. 2005 2012, Hebei Province, the economic growth rate remained at around 10%, greenhouse gas emissions of more than 700 million tons. "13th Five-Year Plan" energy plan pointed out that Hebei Province 2015-2020 unit GDP energy consumption fell more than 18%, China in the "Paris carbon dioxide reduction agreement" in 2020 than the 2005 greenhouse gas emissions by 40% -45%. Many scholars have done research on greenhouse gas emission reduction in Hebei Province. Although many achievements have been made, the existing problems cannot be ignored. First, the lack of greenhouse gas emission reduction research model and forecast research; Second, greenhouse gas emission reduction research for qualitative research, its policies and recommendations are not operational. In order to solve the above two problems, this paper preliminarily creates a dynamic optimization comprehensive evaluation model of the impact of clean energy on the environmental economy. Through the dynamic simulation experiment, the paper analyzes the influence of the development of clean energy on the environmental economy of Hebei Province, and puts forward the science of environmental improvement and economic development in Hebei Province Of the policy program. Model Construction Based on the present situation of social economy and environment in Hebei Province, this paper constructs a comprehensive evaluation model of dynamic optimization of economic impact on the basis of material, energy, value balance and input output. The model includes a objective function and socio economic, energy Balance, greenhouse gas emissions three sub-models. [1] 3rd Annual International Conference on Social Science and Contemporary Humanity Development (SSCHD 2017) Copyright © 2017, the Authors. Published by Atlantis Press. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/). Advances in Social Science, Education and Humanities Research, volume 90


Second part of a research project that intends to characterize the job offers for information professionals in Brazilian Internet sites and discussion lists, between January 2005 and May 2007. It uses Bardin's (2004) technique of content analysis and considers the following criteria: date of offer, source of information, type of professional, city, professional education and function. The results until now demonstrate that most of the offers are for librarians and library assistants in the city of Sao Paulo.


Several productions of Islamic tin glazed pottery from eastern Spain have been studied under the chemical and microstructural points of view by means of WDS, SEM/EDX, XRD and XRF analyses. Samples of Islamic pottery from the workshops of Murcia 10th, Zaragoza 11th, Mallorca 11th, Denia 13th, Granada 14th and Cordoba 10th, which represent a wide range of local productions from medieval eastern Spain, have been studied in order to obtain the trends of the technical and compositional evolution. From the experimental data, some common features can be established, as well as some differences. All the Islamic Spanish opaque glazes are lead glazes with PbO contents from 37 to 56%, opacified with tin oxide in the range 4–15%. In all the cases, they were applied on a previously biscuited body made with a Ca-rich clay, probably to produce a buff colour less apparent through the glaze. The thicknesses range from 100 to 150 microns and the opacification is achieved by small crystals of SnO2(under a micron of size). The main differences are the size and distribution of such small crystals, being smaller in the early Islamic productions (Zaragoza and Murcia) and bigger in the late productions.


The article describes mechanics and features of this twisting frame with single reel and five rollers and double drafting system with its drafting form compared with other double drafting system and some typical fancy yarns introduced.


Muscle strength and mobility decrease with age. Strengthening exercise can prevent decreased muscle strength and mobility. The purpose of this study is to evaluate the effects of home-based Quadriceps femoris strengthening exercise in elderly subjects and its correlation with functional mobility, measured using Timed Up and Go (TUG) test. Thirty-three subjects aged 60 years and above were analyzed in this study. Quadriceps femoris strength was determined using ankle weights that give a perception of "somewhat hard" in Borg Scale after 10 repetitions. Exercise was done at home three times a week, in 3x10 repetitions. TUG test and ankle weights was re-examined on 4th and 8th week. Initial quadriceps strength was 1,4 (0,4) kg. After 4 weeksof exercise, there was 46,61% increment to 2,0 (0) kg and after 8 weeks 95,91% increment was recorded with ankle weight of 2,6 (0,6) kg. TUG test at initial was 11,3 (1,4) seconds. After 4 weeks, TUG improved to 10,0 (1,3) seconds and after 8 weeks to 9,33 (1,40) seconds. Modest correlation (r=-0,354) was recorded between Quadriceps femoris strength improvement and TUG improvement. Quadriceps femoris strengthening exercise can improve muscle strength and mobility in elderly. Keywords: elderly, TUG, muscle strength, quadriceps femoris, home based strengthening exercise.


Friction is the key factor causing turning errors in NC machine tool and the machining accuracy is reduced.It shows strong nonlinearity and bad for the high precision control.Friction compensation was realized on the open NC system by acting compensation pulses to the velocity control loop and the contour accuracy is improved effectively.


The best answers to the fuel crises compelled to survive made a sustainable road transportation. One such effort in this regard is reported in this paper. Due to overcome of power electronics, the population of hybrid vehicle is also hiking up day by day. The Brushless DC motor is considered as potential drive to automotive applications such as the (Hybrid vehicles). Design of a direct drive, Brush less DC motor is employed (BLDC) or (electronically commutated motors). Many constraints have been considered, such as the size of the motor, maximum driving current and maximum output power. The diameter and the stack length are limited by using modern analytical tools of the prototype vehicle. Nobel analytical tools are used to obtain static and dynamic characteristics of the motor and geometrical verifications for low cost efficient design. A low cost electronic controller compatible for present application has been developed and designed in this paper. The prototype is fabricated and tested on a light weight electric vehicle such as the car and two wheeler. This automotive model's performance was tested and its results are simulated in this paper. It has lot of advantages such as the generating power by regenerative braking at speed barkers, recharging the battery while the vehicle is in under the motion.


Close range ion/atom collisions may deposit a large amount of energy on the target (molecule or cluster). The interaction projectile/target is dependent on the nature of the projectile, its charge state and its initial energy. Tuning the experimental conditions, thus the kinetic energy of the projectile, one may be in dominant nuclear stopping regime or dominant electronic stopping regime. The former implies that non-statistical processes, where the energy deposited is not evenly distributed among all the vibrational degrees of freedom of the target, are likely to play an important role in the target decay. The latter sees a largely dominant 'slow' statistical decay for the target. Understanding the relative weight of these two processes and unveiling the fine chemistry of the fragmentation pathways involved may found applications in understanding e.g., the origin and evolution of complex molecules in space, the radiosensitivity of biomolecules and the role of the water environment in the process. In this work we have used classical and ab initio molecular dynamics simulations combined with electronic structure calculations to reproduce entire sequences of collisions and to get insights on the fragmentation pathways induced by the energy deposition consequent to the collision. Chapter 3 summarizes the basics of the electronic structure methods used; while chapters 4 and 5 describe the classical and the ab-initio methods employed, respectively. In this thesis we have investigated four four di erent systems: butadiene clusters, porphyrin, protonated and deprotonated, and 5-halo-substituted uracils. Polycyclic Aromatic Hydrocarbons (PAHs) are ubiquitous in space. Previous studies have already observed molecular growth, induced by nonstatistical decay. In Chapter 6, we have explored the possibilities of forming ring structures, which may be PAHs precursors, from butadiene clusters. We have used a combination of a reactive force-field potential (AIREBO) and a Coulombian screened potential (ZBL) to reproduce the nuclear scattering dominated processes visible in the experiments. The analysis of the results indicates the prompt atom knockout as the main responsible for the molecular growth observed in the experimental mass spectrum. DFT electronic structure calculations, at B3LYP/cc-pVDZ level of theory, suggest the formation of benzene-like ring structure products. In the biological world, porphyrins are among the most common molecules, for this reason they have been proposed as a biomarker for assessing the origin of extra-terrestrial planets, meteorites, comets and so on. Chapter 7 explores the influence of knockout on the mass spectrum of 5,10,15,20-tetraphenylporphin (TPP) and its metallate derivatives, FeTPP+ and ZnTPP+, with a computational approach similar to the one adopted in Chapter 6. To the best of our knowledge, fingerprints of heavy atom knockout have not been identified so far in porphyrins mass spectra. The comparison between simulated and experimental mass spectra evidences the presence of heavy atom knockout. The calculations of the heavy atom knockout cross sections made us conclude they constitute the ≥ 40%(≥ 70%) of the total experimental cross sections of TPP in collision with He (and Ne). Adenine is the nucleobasis which could best survive in an harsh environment like the Insterstellar Medium. In addition, the study of its protonated and deprotonated forms may give insights on the protonation and deprotonation e ects in DNA. In Chapter 8, the stability of protonated and deprotonated adenine has been subject of a combined experimental and theoretical study. The computational approach consisted of a mixed statical and dynamical approach. We have performed ab initio molecular dynamics (ADMP type, at B3LYP/6-31++G(d,p) level of theory) in order to quantitatively reproduce the experimental mass spectrum features, such that fragments structures and fragmentation pathways could be identified. 5-bromo-uracil (5BrU) is a known mutagen and may be used as a model system for the radiosensitizer 5-bromo-2-deoxy-uridine. In Chapter 9, we have explored the influence of the water environment in the decay of 5BrU. This work uses a statical-dynamical approach similar to the one already described in Chapter 8 to study the nano-hydrated 5-bromo-uracil cluster. The ab initio molecular dynamics (BOMD type, at M06-2X/SVP level of theory) suggested an unexpected channel: the water insertion on the [5BrU-H]+ residue. The electronic structure PES exploration (at M06-2X/6-311++G(d,p) level of theory) of the neutral, ionized, protonated and [5BrU-H]+ species has provided pathways and structures, which could explain some of the interesting features of the experimental mass spectrum of hydrated 5BrU, provided from our collaborators from Caen University and CNR Rome. Following the results of Chapter 9, we have investigated the nucleophilic water attack on other halo-substituted uracil (5ClU and 5FU) and uracil (U) itself. As all these molecules are mutagens and/or model systems of radiosensitizers, we aimed, through the observation of similarities and differences in the chemistry of all of them, to shed some light on the chemical mechanisms of mutagenesis and radiosensitivity. The PES sampling involved all the neutral, ionized, protonated and [5XU-H]+ species for each molecule. The results not only suggest an influence of the substituted moiety in position 5 on the reaction mechanism, but also an influence of additional water molecules when bound to the nucleophile.


The analytic properties of the effective dielectric constant of a class of three-phase composite materials are studied. Specifically, we investigate the effective dielectric constant of a periodic array of coated cylinders, as a function of the core dielectric constant (ϵc) and the shell dielectric constant (ϵs), while keeping the matrix dielectric constant (ϵb) fixed. We show that when ϵs = – ϵc, the composite has exactly the same effective dielectric constant as a periodic array of solid cylinders with dielectric constant ϵc and radius equal to the outer radius of the original coated cylinder. We also show that when ϵs = – 1, the composite has exactly the same effective dielectric constant as a periodic array of solid cylinders with dielectric constant ϵc, and radius exceeding the shell radius. We explore the location of poles and zeros of the three-phase effective dielectric constant in the (ϵs,ϵc) plane. The lines ϵs = – 1 and ϵs + ϵc = 0 are loci of essential singularities. We also comment on the behaviour of the effective dielectric constant in the neighbourhood of the two special points (ϵs,ϵc) = (0,0) and (ϵs,ϵc) = ( - 1 , + 1 ).


Various systems and concepts are being investigated for reducing or eliminating the damage to reactor containment or safety equipment caused by hydrogen combustion. An overview of analytical and experimental programs is presented. Topics summarized include: deliberate ignition, deliberate ignition with pressure suppression, deliberate flaring, nonpowered igniters, and modification of plant atmospheres.


This paper provides the comparative analysis including concepts, validation and limitations of four different synchrophasor measurement based corridor voltage stability indices (VSI) namely: a) Thevenin based equivalent, b) Area Equivalent, c) Power Equivalent and d) Radial Equivalent and Independent (REI) equivalent. To validate these four approaches, continuation power flow solutions are used as a benchmark and equivalent 2-port network is developed for the corridor buses. Moreover, a threshold methodology is proposed for Area, Power and REI based equivalents to facilitate better operator awareness. An enhanced algorithm is proposed to take into account impact of nearest Q-limits for hybrid approach using measurement from phasor measurement units (PMUs) and minimal model information for corridor VSI.


Consistent with his enthusiastic embrace of cultural ecology and cultural materialism, Robert S. Santley (1948-2006) saw the economy as basic to the organization of social and belief systems. We review Santley's contributions to Mesoamerican archaeology in the context of broader issues and debates and introduce the articles that make up this special issue in his memory.


Purpose – The purpose of this paper is to present a new closed‐loop radiative robotic paint curing process that could replace less efficient and bulky convection‐based paint curing processes in automotive manufacturing.Design/methodology/approach – The proposed robotic paint curing processes uses an Ultraviolet LED panel for a heat source, an infra‐red camera for non‐contact thermal signature feedback of cure level, and a robot control strategy that incorporates the cure‐level information in an inverse dynamics control of the robotic manipulator. To demonstrate the advantage of the closed‐loop process in improving cure uniformity, detailed models and discussions of the irradiation process, the robotics and the control strategy are presented.Findings – A simulation‐based comparison of the closed‐loop robotic curing with the open‐loop robotic curing clearly shows the benefits of using thermal signature feedback in improving cure level uniformity.Originality/value – This is a new approach proposed to exploit...


Abstract In the classic Zen and the Art of Motorcycle Maintenance, Robert Pirsig clarifies the meaning of quality in higher education. He identifies two ways of viewing quality‐‐classic and romantic. He argues that the fullest meaning of quality contains both. Using Pirsig's insight as a point of departure, this article explores the nature of both romantic and classic quality in higher education. The ideas of Alfred Whitehead are used to clarify the nature of romantic quality in university life. Finally, the contemporary Quality literature is examined using insights from Pirsig, Dewey and Whitehead. 1I would like to thank members of the committee and SWT colleagues such as Gordon Thyberg, Suji Singh, Brian Montgomery, Sue Hall, Kathlyn Dailey, Kim Graves, Bruce Renfro, Sue McCullough, Vicki Meehan‐Clark, Vince Luizzi, Nancy Warren, Jeff Kaufmann, George Weinberger, and Susan Griffith for their insight and encouragement. Special thanks to Kenneth Ashworth, former Texas Commissioner of Higher Education, for...


Convergence in information communication technology is about real issues of technological innovations and change. It encompasses a combination of benefits and challenges, not only for the market, the industry, or technology sectors, but also for the regulatory regime and the society at large.
Technology convergence offers massive opportunities for the development of new services and the expansion of consumer choice. It certainly expands the overall information market, and is the catalyst for the next stage in the integration of the world economy. Even small business can market globally, thanks to the low cost of a World Wide Web site. Convergence enables a substantially higher capacity of traditionally distinct voice and data transmission services to be transported over similar networks and to use integrated consumer devices for purposes such as telephony, television or personal computing (PC).


A novel theoretical calculation method is proposed to obtain Brillouin power and frequency coefficients for strain and temperature of optical fibers used in Brillouin optical time domain sensors. For a GeO2-doped single mode fiber with any kind of complex refractive index profile, if the profile of refractive index and dopants of the fiber is available, the power-strain and power-temperature coefficients can be, respectively, derived by observing the strain and temperature dependence of Brillouin power through the changes of fiber's effective refractive index, density, sound velocity, and acousto-optic effective area. The frequency-strain and frequency-temperature coefficients can be directly obtained by detecting the strain and temperature dependence of Brillouin frequency. The complex problem of the change of acousto-optic effective area is solved by multi-layer segmentation method. The single mode fiber-28 and large effective area fiber are taken as examples to validate the theoretical derivation. The validity of the proposed method is verified by comparing the calculation results of the Brillouin power and frequency coefficients for strain and temperature with the corresponding experimental results in the literature.


Formal methods can be used to verify different perspective of a Web service. An ensemble of specific techniques is not supported by a general approach to the problem. To understand which formal method should be combined and used is a challenge. This paper outlines our approach to address this problem.


This thesis analysed the universal problem of traversing crane before transformation.Based on this,it propounded some feasible scheme to transform,and summarized the results of transformation.It selective analysis the scheme of adopting the centralized control with PLC and inverter.This kind of technology will be the orientation of the traversing crane line transformation.


The verification of systems combining hard timing constraints with concurrency is challenging. This challenge becomes even harder when some timing constants are missing or unknown. Parametric timed formalisms, such as parametric timed automata (PTAs), tackle the synthesis of such timing constants (seen as parameters) for which a property holds. Such formalisms are highly expressive, but also undecidable, and few decidable subclasses were proposed. We propose here a syntactic restriction on PTAs consisting in removing guards (constraints on transitions) to keep only invariants (constraints on locations). While this restriction preserves the expressiveness of PTAs (and therefore their undecidability), an additional restriction on the type of constraints allows to not only prove decidability, but also to perform the exact synthesis of parameter valuations satisfying reachability. This formalism, that seems trivial at first sight as it benefits from the decidability of the reachability problem with a better complexity than Timed Automata (TAs), suffers from the undecidability of the whole TCTL logic that TAs, on the contrary enjoy. We believe our formalism allows for an interesting trade-off between decidability and practical expressiveness and is therefore promising. We show its applicability in a small case study.


A harmonious university culture should be fostered in the construction of a harmonious university.University culture,conceived in the university education environment,is the reflection of culture on campus and an effective medium through which college students' physical and mental quality can be comprehensively promoted.This paper elaborates the connotation and the characteristics of university culture,and brings home the significance and the mission of constructing a harmonious university culture.Based on an analysis of the disharmonious elements in university culture in the course of building up a harmonious society,it discusses the focal points and the strategy in developing a harmonious university culture.


AbstractThe electron-spin-resonance spectra of transition metal ions Fe in the HgSe matrix are analyzed. The spectra have an appearance typical of the Fe^3+ ion, i.e., they consist of five fine-structure lines with a splitting that corresponds to a weak crystal field. The spectra are observed at temperatures of up to 50 K. The spectral lines are deformed and have a Dyson shape. An analysis of the temperature dependences of the line amplitudes shows that a transition from paramagnetic ordering to ferromagnetic ordering occurs with decreasing temperature, with the Curie temperature T ≈ 7 K.


The C case describes Tom Stark's state of mind after his meeting with the OSIM Group's chairman of the board. See also the A, B, D, E, F, and G cases (UVA-BP-0399, UVA-BP-0400, and UVA-BP-0402 through UVA-BP-0405).


Heteroatom-doping had been demonstrated to effectively improve the capacitive energy storage of hard carbon in potassium ion batteries (KIBs). However, the external defects introduced during doping process are responsible to...


Background: The aim of this project was to provide an expert opinion regarding anti-human epidermal growth factor receptor 2 (HER2) therapy beyond second-line treatment of metastatic breast cancer (mBC). Methods: A group of experts discussed specific issues concerning anti-HER2 therapy in late-line settings in mBC. Results: Trastuzumab emtansine (T-DM1) or dual HER2 blockade appeared to be good options for HER2-positive mBC after ≥ 2 HER2-targeted therapies. Once an objective response has been achieved with anti-HER2-containing therapy, the anti-HER2 agent can be continued until progression of the disease, unacceptable toxicity or patient decision. mBC treated with ≥ 3 consecutive lines of anti-HER therapy, ≥ 1 being a dual HER2 blockade and with early progression of disease during a fourth or later-line treatment, are clinically resistant to anti-HER therapy. For progression of metastasis in the brain after anti-HER2 therapy, lapatinib and chemotherapy appear to be a good alternative after best local treatment. Conclusions: Further clinical trials are needed to provide valuable knowledge about the best treatment options in the later settings of mBC.


Lex C, Hautzinger M, Meyer TD. Cognitive styles in hypomanic episodes of bipolar I disorder.
Bipolar Disord 2011: 13: 355–364. © 2011 The Authors.
Journal compilation © 2011 John Wiley & Sons A/S.


This paper presents a cell-based 50% Duty-Cycle Correction (DCC) design supporting a super-wide range of clock frequency from 10MHz to 1.2GHz, using a 90nm CMOS process. It can be integrated with a Delay-Locked Loop (DLL) as a convenient post-processing unit while achieving "zero phase shift" in a way that the phase locking result achieved by its precedent DLL is not affected at all. The unique features in this design include: (1) A wide-range and high-resolution Half-Period Tunable Delay Line (HP-TLD), (2) A fast-locking unit to enable our DCC to lock in to a new incoming clock frequency during frequency scaling, and (3) A wide-range and high-resolution Duty-Cycle Judge (DCJ) circuit as a feedback to guide the overall duty-cycle correction process. Post-layout simulation in a 90nm CMOS process is conducted to validate its effectiveness.


How did ancient Israel think of heaven? What place did it have in its view of the world? The Old Testament attests to a strikingly wide variety of concepts of heaven and, simultaneously, to a very close association between heaven and earth. This study pays cosiderable attention to these topics and to the theme of heaven as God's realm and residence. Among the conclusions drawn are: for ancient Israel, heaven and earth (the principal components of the world) constituted a dynamic bipolarity which was connected with mankind at one pole and with God at the other; the Old Testament has no world-concept ("Weltbild"). It does not give an unanimous answer to the questions concerning the "how" of the cosmos coming into existence, and the "how" of its structure and order. It does, however, imply a world-view ("Weltanschauung"), ie it answers the question to "whom" does the world owe its birth and existence?


Pycnidial fungi belonging to the genus Ampelomyces are common intracellular mycoparasites of the Erysiphaceae worldwide. As a part of a project which aimed to isolate and test potential biocontrol agents of powdery mildew infections of economically important crops in China, a total of 23 Ampelomyces isolates were obtained from many different species of the Erysiphaceae in five provinces of China. In addition, four new Ampelomyces isolates were obtained in Europe for this study. Mycoparasitic tests showed that all the 27 new isolates produced intracellular pycnidia in the conidiophores of Podosphaera xanthii and/or Golovinomyces orontii when these powdery mildew species were inoculated with conidial suspensions of the isolates. This confirmed that the new isolates can be identified as Ampelomyces mycoparasites and they were not confused with other pycnidial mycoparasites of powdery mildew fungi. The ITS sequence of the nuclear rRNA gene of the 27 new isolates were analyzed together with 20 sequences of other Ampelomyces isolates determined in earlier studies. The ITS sequences of some isolates obtained in China were identical with those of some European and/or North American isolates which indicates a global distribution of these mycoparasites. At the same time, 16 Chinese isolates formed a distinct group, which was only distantly related to the already known groups of the European and the North American Ampelomyces isolates. Ampelomyces mycoparasites with similar or identical ITS sequences were found in different powdery mildew hosts in China. Also, mycoparasites with different ITS sequences were isolated from the same powdery mildew species during this study. Thus, no correlation was found between the ITS sequences of the mycoparasites and the host fungi and host plants where they came from.


Photograph shows young boy, listening to radio, sitting in front of easel drawing a picture.
Copyright 1924 by Morris Rosenfeld, New York.
No. 18884.
Title from item.


This research is about the secularization of schools by anticlericalism. The law Coppino and the abolition of the religion hour in school. The debate between Catholics and leftism about the abolition of religion.


A perceptually based video encoder for monochrome image sequences is presented. It incorporates characteristics of the human visual system to detect, track, and encode image blocks (of 8*8 pixels) perceived to be in apparent motion. The Weber relation in the spatio-temporal domain is used for motion detection. A decimation-interpolation scheme is developed to produce good quality video at very low-bit-rates. An efficient technique based on the discrete cosine transform and vector quantization is developed to encode image blocks which have changed beyond a perceptual threshold. The new encoder is demonstrated to yield competitive quality video at low-bit-rates.<<ETX>>


This paper considers a model for the growth of a solid tumor with a single anticancer agent application.The model is a free boundary problem of a nonlinear reaction-diffusion-advection equation,where the free boundary is the surface of the tumor.Since multicellular spheroids are routinely used as in vitro(i.e.,outside live organisms)models of cancer growth and they can be observed and controlled in the laboratory,the following inverse problem is studied:given observed dynamics of tumor growth,a certain parameter is determined.The Lipschitz stability of solutions to the above-mentioned inverse problem is established,and this inverse problem is solved by control theory.Numerical methods for solving the inverse problem are also given.


In this paper, the significant electromechanical properties of the novel high-temperature piezoelectric single crystals YCa4O(BO3)3 (YCOB) were fully characterized over the temperature range from room temperature to 800 °C, including the dielectric, elastic, and piezoelectric properties, and electromechanical coupling coefficients and mechanical quality factor. More importantly, the complex coefficients were completely determined which take into account the mechanical and electrical losses of the material and, therefore, can describe the crystal behavior more accurately. The complete measurement procedures and calculation methods required to obtain all of these parameters were proposed. YCOB resonators with 23 different types of orientations were designed and measured, and all of the independent dielectric, piezoelectric, and elastic coefficients (4, 10, and 13, respectively), 6 important coupling factors, and the mechanical quality factor were determined. It was found that (1) the dielectric permittivity and loss increase dramatically and nonlinearly with the rise of temperature; (2) the elastic compliance constants basically increase linearly as the temperature rises, while the stiffness constants decrease linearly; (3) the piezoelectric charge constants dij increase slightly with the elevated temperatures; (4) the coupling factors and mechanical quality factor decrease linearly with an increase of the temperature, and the coupling factors are in the range of 0.005–0.052, and the quality factor drops from 10 300 to 1300 with the temperature increasing from room temperature to 800 °C.In this paper, the significant electromechanical properties of the novel high-temperature piezoelectric single crystals YCa4O(BO3)3 (YCOB) were fully characterized over the temperature range from room temperature to 800 °C, including the dielectric, elastic, and piezoelectric properties, and electromechanical coupling coefficients and mechanical quality factor. More importantly, the complex coefficients were completely determined which take into account the mechanical and electrical losses of the material and, therefore, can describe the crystal behavior more accurately. The complete measurement procedures and calculation methods required to obtain all of these parameters were proposed. YCOB resonators with 23 different types of orientations were designed and measured, and all of the independent dielectric, piezoelectric, and elastic coefficients (4, 10, and 13, respectively), 6 important coupling factors, and the mechanical quality factor were determined. It was found that (1) the dielectric permittivity...


This article describes the research project carried out with a blind student, who studied French at a public university. The pedagogical experience over three years began in a classroom when a foreign language teacher and educator felt herself "handicapped," as she had not been prepared for working with blind people. In order to put her student on the same level of other students in terms of study possibilities, the teacher entered the blind and visually impaired students' world through Braille. She designed methodologies in order to encourage the autonomous learning of the foreign language as well as tried to motivate other blind or visually impaired people to acquire the same knowledge.


-Lessons learned and evaluation Literary Appreciation tend to be neglected: less procedural, less precise, and less effective. Measuring appraisal tools of literary appreciation are mostly only up to the level of knowledge (cognitive), not to measure the psychomotor and affective aspects. Therefore, the purpose of this study was to develop an authentic assessment model to measure the achievement of KD learning ability to appreciate literary texts in the Curriculum 2013 at high school level as a strategy to form the noble character of the nation's youth. Assessment development of the ability to appreciate this literary text needs to be done by first doing needs analysis, KD analysis, material analysis, and student analysis. The design of the implications of developing an authentic assessment model of learning the ability to appreciate literary texts is guided by KD learning to appreciate literary texts (short stories) and its training stages include understanding, producing, and comparing text. In addition, it is also guided by the training of language aspects in the Curriculum 2013. Keywords--ability to appreciate, short story text, development of authentic assessment model, authentic assessment instrument


This contribution deals with sound sourcelocalization in the three-dimensional space. An energeticanalysis method based on B-format signals processing ispresented in this paper. This method is able to localize multiplesound sources in the three dimensional space. A singleSoundField microphone can be used to pick-up B-formatsignals indirectly. The method has been simulated in Matlaband tested in a real environment. Experimental resultsdemonstrate the validity of this method.


The research is financed by Ministry of Education of Ethiopia in general and Wollega University particularly Abstract This study focused on decomposion of gender differential on agricultural productivity. The agricultural productivity difference between male and female headed households was about 57.18% in the study area. On the other hand, if female headed households had equal access to the inputs as male headed households, gross value of the output would be higher by 18.82% for female headed households. This may suggest that female headed households would have been more productive than male headed households if they had equal access to inputs as male headed households. Thus accessing female headed households to inputs that increase the productivity of land, labour utilization, usage of herbicide; and introducing technologies that reduce the time and energy of women is essential to improve the agricultural productivity of women and the society as a whole. Keywords: Aira, Decomposition Model, Gender, West Wollega DOI : 10.7176/JAAS/60-01 Publication date: January 31 st 2020


Aiming at the few investigation of 220 k V icing composite insulator w ith four sheds at home and abroad,this paper analyzed the influence of icicle length and grading ring parameter,position on the electric field distribution of 220 k V icing composite insulator w ith four sheds w ith using the finite element analysis softw are Ansoftmaxw ell. The results show that:( 1) under the icing condition,w hen the gap betw een w et iced and large shed is 1 mm,the composite insulator bridged w ith icicle w ill not discharge w hen its large sheds,but it w ill have discharge risk under over voltage w hen the composite insulator is not bridged w ith icicle;( 2) grading ring can significantly improve the electric field distribution betw een high voltage side and the first large shed;( 3) the electric field distribution of the gap betw een high voltage terminal and nearby icicle can match best w hen grading ring 's vertical distant from fitting connection point is 0 mm,its outer diameter is 306 mm and pipe diameter is 36 mm.


Photocurrent response of CrI3 junction device. (A) Schematic of a four-layer CrI3 junction device in AFM ground state (????), with top and bottom graphene contacts and hBN encapsulation. (B) I-V curves of a fourlayer CrI3 junction (D2) under dark condition (black curve) and with 1 ?W of 1.96-eV laser excitation (red curve). Inset is a zoomed-in view of the generated photocurrent at zero bias Iph and open-circuit voltage Voc. (C) Differential reflectance (?R/R; black dots) and photocurrent (Iph; blue squares) as a function of photon energy for trilayer (3L) CrI3 at ?2 T. The photocurrent is measured from a trilayer CrI3 junction device (D1) with an optical power of 10 ?W. (D) Optical microscopy image of the 3L CrI3 junction device (D1). Scale bar, 5 ?m. (E and F) Spatial maps of photocurrent and RMCD signal measured from the same device at 0 T with an optical power of 1 ?W. Scale bars, 5 ?m. Credit: Science Advances, 10.1126/sciadv.abg8094


and promote insulin resistance. We suggest that Grau et al. include measurement of abdominal circumference as an indicator of abdominal obesity, take into account menopausal status in women, and determine low-density lipoprotein cholesterol and triglyceride levels. As demonstrated in a number of studies, these variables are easy to determine noninvasively and are useful. Despite the questions raised in the present article, we consider the work carried out by these authors to be excellent.


Mucopolysaccharidosis (MPS) is a group of metabolic disorders caused by a deficiency or malfunctioning of the lysosomal enzymes needed to break down molecules called glycosaminoglycans (GAGs).


Sixteen-year-old Becky is about to have her life changed. A dramatic explosion is only the start of her incredible adventure. As maid to the cockney Crown Princess of a tiny kingdom in Europe, she is plunged in a turmoil of murder and intrigue.


Objective To explore the influential factor of short-term prognosis in advanced stage patients with chronic severe hepatitis(CSH) B.Methods A retrospective chart review and statistical analysis were done on 45 patients consecutively admitted to CSHB.Results Thirty-one patients died during 30 days,mortality was 68.9%,hepatic encephalopathy(HE) was mainly cause of death(71.0%),next was multiorgan dysfunction syndrome(22.6%),admission MELD scores(P 0.05) and total bilirubin(P0.01) were independently associated with 30 days mortality,multiple factor Logistic regression analysis showed total bilirubin(P0.01),MELD scores(P0.05),and Child-Turcotte-Pugh(CTP) scores(P0.05) were associated with short-term mortality.e antigen and sexuality in short-term prognosis were significantly different(P0.05).Conclusion High risk factor of short-term in advanced stage CSH is negative e antigen,hepatitis B,male,TBIL,HE,hepatorenal syndrome(HRS) on admission.MELD and CTP score on admission can be used to evaluate short-term prognosis.


The intrusion detection technique is used to compensate the drawbacks of firewall and it plays an important role in the procedure of network running.As attacks on the network are becoming more complicated,the agent technique is introduced to develop a detection system of distributed intrusion,and its performance is enhanced.The technique of intrusion detection is analyzed and classified in this paper.The affection of agent technique for the detection system of distributed intrusion is described.Some key techniques to be used to develop the detection system of distributed intrusion are proposed and discussed.The methods to solve these key techniques are illustrated in detail.


The threshold temperature and effective accumulate temperature of Pieris rapae L. were tested at the following five constant temperatures (18℃, 21℃, 24℃, 27℃, 30℃). The results showed that egg, larva and pupa could normally develop between 18-30℃. The optimal temperatures of the growth and development were between 24-27℃. All the relationships betweens developing rate and temperature followed linear forms. The threshold temperature of eggs, 1st larva, 2nd larva, 3rd larva, 4th larva, 5th larva and pupa were 8.4℃, 8.8℃, 8.3℃, 8.3℃, 8.6℃, 8.6℃, 14.5℃ respectively. The effective accumulate temperature were 56.4, 53.8, 53.1, 53.1, 47.7, 47.7 and 82.8 day-degrees respectively. The Develop- ment duration of eggs, larva and pupa were 4-8 d, 11-22 d, 5-16 d respectively. Adult life was about five days. It took place 4-6 generations in one year of Yan'an.


Time-dependent chloride penetration into concrete subjected to airborne salt was examined by the manufactured wind tunnel. Surface chloride and diffusion coefficient were experimentally derived. Chloride penetration into concrete was recalculated by several computational models. It was clarified that the combination of concentration-dependent diffusion coefficient and natural type of boundary condition can simulate well chloride profiles in both short and long term chloride profiles.


national law, published respectively in 1983 and 1991,1 Professor Harris excised extracts from the judgment of the Nuremberg Tribunal and from the Genocide Convention which had appeared in the earlier edition. While some international lawyers might have regretted the decisions, few would have taken serious exception to them. After all, trials of "international crimes" took place, if they took place at all, before national tribunals, which Professor Harris acknowledged by retaining extracts from the Eichmann case. The expectations engendered by the Nuremberg trials and the Genocide Convention seem destined to remain unfulfilled. Given the conditions of the Cold War, it was hardly surprising that no practical steps were taken to further the project for an international criminal court envisaged in the Genocide Convention. During that period, however, substantive international criminal law, as that term is widely understood, did develop. The Geneva Conventions of 1949 instituted an obligation on States to prosecute under their own laws or to extradite to another State which would prosecute those responsible for "grave breaches" of the law of armed conflict, obligations which were extended by Protocol I in 1977. It was widely accepted that the conduct which States were required to make criminal was also criminal in international law-"war crimes" in the sense of the London Charter.2 On the other hand, it was not so readily conceded that other breaches of the Geneva Conventions, notably those applicable to internal conflicts under common Article 3, did involve criminal responsibility in international law; likewise, the additional provisions made under Protocol II.3 Similar uncertainty surrounded other provisions in international treaties, the principal obligation of which was that States should make defined conduct criminal in their own law. This was particularly the case with the "anti-terrorism" conventions and the various treaties directed against international drug-trafficking.4 Rather more controverted was the position of torture as an international crime.


LiFePO4 cathode material had been synthesized by using tri-n-butyl phosphate(TBP) as a multi-function agent and polyethylene glycol 4000(PEG-4000) as a surfactant and carbon source.The products were detected by means of X-ray diffraction(XRD),scanning electron microscope(SEM) and X-ray photoelectron spectroscope(XPS).The results indicated that the sample prepared at 650℃ for 15h was well crystallized with small and homogeneous global particles.In the voltage range of 2.5-4.3V(vs Li),cyclic voltammetry tests showed there was a pair of sharp redox peaks with almost equal areas,indicating the material an excellent reversibility.Electrochemical tests exhibited that the first discharge capacity was 158mAh/g at the current density of 0.1mA/cm2.After 100th cycle,the specific discharge capacity was 153mAh/g with only the loss of 3.3%.Even at the high current density of 4.0mA/cm2,it still showed the discharge capacity close to 100mAh/g.


The case involved a 63-year-old female who had complained of a hard reddish lump in the right breast. Although the lump initially appeared to be a phyllodes tumor, histopathology after initial surgery indicated mastopathy as a likely diagnosis. Two years later, regrowth of the lump at the same location prompted revaluation. Ultrasound scan (US) revealed the following features : a) an irregular low-signal lesion with a diameter of 5 cm in the right A region extending toward the hypertrophic epidermis, b) marked increase in blood flow on power Doppler, c) increased thickness between the skin and underlying pectoralis major, and d) irregular and unclear margin of low-echoic lesion. Based on those findings along with clinical symptoms, advanced stage of inflammatory breast cancer was suspected, and a second surgery was performed. Histopathology revealed infiltration of atypical spindle cells around normal mammary ducts, but it did not show the architecture of a phyllodes tumor. The atypical spindle cells were positive for vimentin and CD34 and negative for hormone receptors according to immunohistochemistry. These were consistent with the characteristics of periductal stromal sarcoma. The section diagnosed as mastopathy 2 years previously was re-evaluated by pathologists, and components of stromal sarcoma were found in the section. Stromal sarcoma is rare for the breast region and usually lacks specific features, which may make the precise diagnosis quite difficult. In our case, the following factors contributed to the misleading diagnosis : invasive growth without forming a firm mass, less prominent nuclear pleomorphism and low proliferation index, and inconsistent US features compared to the previous report, etc. The generally poor prognosis of this tumor should demand long-term observation even though no recurrence has been found after the second surgery.


Tourism as the subject of doctoral research has been extensively explored, with previous studies tending to focus on the disciplinary orientation of doctoral research. Yet few studies have considered the proliferation of specific topics into tourism doctoral research. Sustainable tourism is a significant and influential topic that has emerged in importance over the past three decades. However, little research has focused on sustainable tourism as the subject of doctoral dissertations. Consequently, this presentation explores the growth and themes in doctoral research focused on sustainable tourism by mining an existing database of 1,888 tourism dissertations from the US, Canada, Australia and New Zealand. Preliminary results indicate that 206 (11%) of the dissertations in this database were focused on sustainable tourism, with the highest proportion being from Canada. The presentation further explores the key findings of this research and discusses the implications for tourism education and higher degree research training.


A linear electric motor includes a fixed member polymers, having a linear axis of the shaft, the polymeric actuator and biasing member. The polymer actuator comprises a first end portion fixedly connected to the linear axis and a second end portion fixedly connected to the fixed member. A first end of said biasing member comprises a shaft fixedly connected to the linear portion and a second end fixedly connected to the fixed member. The polymer actuator changes length to move linearly along the axis after receiving the linear axis voltage. In another embodiment, an apparatus comprising a flexibly coupled to the base of the oscillation bridge. The apparatus further comprises a portion having a first end coupled to the base polymer and a second end coupled to the bridge portion of the oscillating actuator. The voltage applied to the polymer actuator to translate relative to the base bridge oscillations, so that the oscillation bridge linearly traveling parallel to the base.


The purpose of this study is to investigate the relationship between passenger travel demand and land use in Seoul. In particular, we attempt to examine the impacts of the structural changes in the socio-economic environment in Seoul since IMF at the end 1990's on the passenger flow patterns. In order to examine the dynamic interrelationships between the passengers at the subway station and thirty six land use variables, we develop twelve models with various combinations of three years(2000, 2003, 2006) and four different data units. By applying multivariate regression analysis, we obtain twelve log-linear regression functions. In order to develop better regression model which explain more the passenger flows, we check the determinant coefficient R² and selected explanation variables at each model. In general, models using Gu as the regional unit for the land use variables give better explanation for the subway passenger demand. We examine also the changes in the satial distribution patterns of passenger flows and land use variables selected commonly in the models as the major passenger travel generators. Significant changes are detected both in the passenger flows and in the land sue patterns during this period. In particular, major central functions which are related with travel demand generation show the big increase in the Gangnam CBD area same as passenger travel demand, while they have decreased in the old CBD in the Gangbuk.


ABSTRACT Historic documents indicate that during the Yarlung Dynasty (AD 620–AD 842), Tibetan emperors employed geomantic and magical practices in the design and siting of important religious structures. Geomantic magic was used to control indigenous demons that inhabited the land thereby obstructing the introduction of Buddhism and the building of temples and monasteries. In the present article, the Jokhang and Tradruk temples and Samye Monastery are assessed from a landscape archaeology perspective to identify geomantic and magical practices in their design and layout. New findings are presented to include sitings relative to dragon veins, the use of deadly feng shui arrows, and the suppression of demons using ritual phurbas, vajras, and magical mandalas. The demon suppressing methods discussed represent a blend of indigenous Tibetan magic combined with beliefs and practices from China and India. The result was a unique and powerful magico-religious tradition that endures even today.


The eastern Tseel Terrane of SW Mongolia, which is an important part of the Central Asian Orogenic Belt (CAOB), contains a segment of imbricated sheets of Late Palaeozoic granites as well as a bimodal volcanic suite. Late Devonian (380–382 Ma) granites that are enriched in Th, U, and K and depleted in Nb, Ta, P, Ba, Sr, and Ti indicate arc magmatism and are low‐K tholeiitic to medium‐K calc‐alkaline series. Zircon εHf(t) values are of +8.30 to +14.1, with crustal model ages of 0.83–0.48 Ga. The bimodal volcanic suite is composed of N‐MORB basalt and 302 ± 2 Ma rhyolite having A2‐type granite affinities, εHf(t) values ranging from +9.9 to +11.9, and crustal model ages from 0.69 to 0.59 Ga. The rhyolite mighthave originated from partial melting of juvenile lower crust, rather than fractional crystallization of coeval basaltic magma. Late Carboniferous (299–303 Ma) granites are medium‐K to high‐K calc‐alkaline series, cross‐cutting carbonaceous siltstone, emplaced into the deformed volcanic rocks and are characterized by enrichment in K, Th, and U accompanied by depletion in Ba, Nb, Ta, Sr, P, and Ti in a primitive mantle‐normalized diagram with εHf(t) values ranging from +6.05 to +10.6 and crustal model ages from 0.70 to 0.65 Ga. Thus, LA‐ICP‐MS zircon ages in combination with geochemical data document a phase of arc‐related magmatism in the Tseel Terrane at 380–382 Ma. These rocks were subsequently deformed under low‐grade metamorphic conditions and intruded by undeformed granites at c. 299–303 Ma. The coeval 302 Ma rhyolite in bimodal volcanic suite shows typical A2‐type granitic geochemical affinities and probably documents a back‐arc basin extensional environment, which was probably related to the roll‐back of the Palaeo‐Asian Oceanic Plate during the northward subduction under the Central Mongolia microcontinent.


The invention provides full-nutrition formula food, specific full-nutrition formula food or non-full-nutrition formula food suitable for the aged. The full-nutrition formula food is developed based on physical characteristics of the aged, according to the requirement of General Principles of Special Medical-Purpose Formula Food, by integrating research achievements of advanced physiology, medicine, nutriology, clinical application and the like of Harvard University at present and according to the traditional Chinese medicine essence theory of eliminating while replenishing and balancing and regulating (with a main principle of simultaneously regulating liver, spleen and kidney). The full-nutrition formula food is prepared by mixing main raw materials and auxiliary materials, wherein the main raw materials comprise a variety of edible and medicinal traditional Chinese medicine extract essences, a variety of probiotics and oligopeptide; the auxiliary materials comprise probiotics, carbohydrates, amino acids and a variety of vitamins and mineral substances. The full-nutrition formula food can be used as a single nutrition source for meeting the nutrition requirements of the aged and also has the functions of warming the kidney, strengthening yang, tonifying deficiency, reinforcing qi, nourishing blood, tonifying kidney, securing essence, dispersing blood stasis, descending the turbid, restoring yang and relieving desertion, warming and activating meridian, building body, prolonging life and enhancing immunity.


This article is aimed to analyze the local industrial linkage and localization of foreign direct investment companies in Korea. To accomplish this purpose, it analyzes the local industrial linkage, the employment effect and networking between FDI companies and regional social institutions, with an interview and questionnaire survey. The findings of this analysis are as follows. First, FDI companies are supplied materials less than their regions(15.2%) than from abroad(33.6%). Second, comparing with their purchase of materials within the regions, FDI companies are selling relatively much more products within the regions(42.4%). Theses patterns of local purchase and sales are closely connected with FDI companies' tendency to increase investment for the purpose of securing find a market. Third, all the FDI companies, which are located both in the capital and other regions, tend to work with institutions placed in the capital region in reference to the business service such as legal, accounting and tax matters. Fourth, the extent of technological transfer is limited. Fifth, the employment effect of the FDI companies is higher than that of other domestic companies in the manufacturing sector and regional employment effect is also high. An average of employment of FDI companies is 117 persons and the employment rate grows 4.6% than initial investment year. In addition, two-thirds of the surveyed FDI companies have cooperated with other domestic(subcontract) firms and onethird have had alliances with domestic firms. Interchanges between FDI companies and regional social institutions are few and are limited to mutual friendship. In Conclusion, the FDI companies in Korea can be classified to a "dependency model" in aspect of local industrial linkages and localization.


This study examines the impact of firm reputation and CEO experience to company performance after merger and acquisition. The sample of this research are companies listing on the Indonesia Stock Exchange and register their M&A action to the Indonesian Commission for the Supervision of Business Competition. The time frame for selecting data is from 2014 to 2019. The research data are tested and analyzed with multiple linear regression methods on SPSS Software by using 110 sample data. The results of the data test prove that the acquisition experience in the same industry and the measurement of the company's capitalization reputation have a significant positive impact on company performance. Following the concept of knowledge transfer theory and organizational theory, acquisition in same industry will increasing company value and performance in competing with other competitors with more focused and can create cost saving. These will have an effect on company performance by get a good response in public and achieve a competitive advantage. Novelty of this research provides a new insight for firm reputation measurement that are still relevant to be used for measure firm reputation. The managerial implication of this research will provide a new insight for management a new requirement when selecting a CEO for doing merger and acquisition and the relevant firm reputation measurement that the company should focusing developing.


The "Sorting Hat", inspired from Harry Potter by J.K. Rowling was designed as a mediator social robot for autistic children. Since they are unable to interact with peers and show their emotions, the hat plays the role of a mediator to fill the communication gap. It is recommended to use the Sorting Hat in environments where children interact or in a domestic area. The hat was tested with 430 random set of volunteers to measure the attraction, the interactivity in use and the data demonstrated positive results. It also consists of an EEG sensor to record the raw brain wave data for future cognitive analysis.


AbstractThe potential that mannose receptors on alveolar macrophages (AMs) may be targeted using mannose-conjugated liposomes for intracellular drug delivery to AMs was investigated. A mannosylphospholipid was synthesized via the reaction of α-d-mannopyranosylphenylisothiocyanate with dipalmitoyl phosphatidylethanolamine, and the product was identified using thin-layer chromatography and nuclear magnetic resonance spectroscopy. Liposomes containing this mannosylated phospholipid were made using a high-pressure homogenization method and analyzed using freeze-etch electron transmission microscopy. These liposomes were shown to exhibit unilamellar structure with a mean diameter of 140 ± 59 nm. The uptake of liposomes by rat alveolar macrophages, by measurement of internalized, liposome-encapsulated fluorescein, was found to be both dose and time dependent. The uptake of liposomes containing 40% mannosylphospholipid was 3.6-fold higher than that of liposomes without the mannosylated lipid (16% to 4.5%). Fluor...


Sex differences in bladder cancer pathology and epidemiology have been the focus of recent research. We investigated the epidemiological characteristics and compared bladder cancer pathology and survival between men and women in Japan. A total of 13,184 patients with primary bladder cancer diagnosed from 1954 to 2010 were identified in a large‐scale cancer registry database in Kanagawa Prefecture. Using this database, we compared the odds ratios (ORs) for nonurothelial carcinoma (non‐UC) using a multiple logistic regression model adjusted for age and diagnosis periods. We also compared hazard ratios (HRs) for overall death and cancer‐specific death using a Cox proportional hazards model adjusted for non‐UC, age, and diagnosis period. The proportion of non‐UC was significantly higher in female compared with male patients (OR = 2.14, 95% confidence interval [CI]: 1.81–2.52). Furthermore, survival was significantly poorer in female patients than in male patients after adjusting for UC or non‐UC (HR for overall death = 1.15, 95% CI: 1.06–1.23; HR for cancer‐specific death = 1.39, 95% CI: 1.28–1.52). Sex differences exist in the epidemiological characteristics of bladder cancer in Japan, with female patients having less favorable pathology and poorer survival compared with male patients.