Although a century ago the life expectancies of men and women were about equal, the life expectancy at birth between the sexes has grown in the past four decades. In most industrialized societies across the globe, men tend to have more opportunities, privileges, and power than women, yet these economic and social advantages do not translate into better health outcomes. In recent years, there have been important global efforts to document the ways in which women fare better than men across a number of health outcomes, but the European Commission's report on the state of men's health in the European Union and other efforts have been criticized for not attending to disparities among men. Men's health research has primarily focused on the extent to which social and cultural factors shape men's health practices and health outcomes, but an important gap exists in how we explain differences in health among men. Men's health disparities are differences in health outcomes that are determined by cultural, environmental, and economic factors associated with socially defined identities and group memberships. This special issue of Behavioral Medicine helps to fill this gap by using a biopsychosocial approach to explaining health differences and health disparities among men in and to inform future research and policy to improve men's health. This body of work also highlights the critical role that an intersectional approach can play in systematically moving the field forward through research and policy.


The invention discloses a chip on film package. The chip on film package includes a base film, a chip and a heat-dissipation sheet. The base film includes a first surface. The chip is disposed on the first surface and having a chip length along a first axis of the chip. The heat-dissipation sheet includes a covering portion and a first extending portion connected to the covering portion and attached to first surface. The covering portion at least partially covers the chip and having a first length along the first axis. The first extending portion has a second length along the first axis substantially longer than the first length of the covering portion, and the covering portion exposes a side surface of the chip, wherein the side surface connects a top surface and a bottom surface of the chip.


High-throughput and area-efficient designs of hash functions and corresponding mechanisms for Message Authentication Codes (MACs) are in high demand due to new security protocols that have arisen and call for security services in every transmitted data packet. For instance, IPv6 incorporates the IPSec protocol for secure data transmission. However, the IPSec's performance bottleneck is the HMAC mechanism which is responsible for authenticating the transmitted data. HMAC's performance bottleneck in its turn is the underlying hash function. In this article a high-throughput and small-size SHA-256 hash function FPGA design and the corresponding HMAC FPGA design is presented. Advanced optimization techniques have been deployed leading to a SHA-256 hashing core which performs more than 30% better, compared to the next better design. This improvement is achieved both in terms of throughput as well as in terms of throughput/area cost factor. It is the first reported SHA-256 hashing core that exceeds 11Gbps (after place and route in Xilinx Virtex 6 board).


In the paper many sides to the computing of stability are considered. It is shown that from point of view of the time and the cost of computations it is advisable to join the equations of motion with a ``fixed point'' of the aircraft. Also it is advisable to project these equations on the stability axes (i.e. axes, which are connectcd with the vector of undisturbed flow). An advantage of usage of the stability diagrams in the design modification is mentioned.


This study contributes to phytotherapical knowledge of different tribes District Poonch. The study was conducted in order to obtain the indigenous knowledge of the local inhabitants on phytotherapical uses of various plants. The present study indicates that the tribes of District Poonch utilized 44 p lant species belonging to 20 families in everyday life as medicine. A large number of peoples belonging to various tribal groups were interviewed during many field trips and asked questions regarding the phtotherapical use of plants. In the present explorat ion, phytotherapical informat ion on plant species collected was presented in a precise manner. The various plants along with their Botanical names, Family, Common name, part used and used against were discussed in this paper.


The only evidence that seeing in slow-motion exists comes from retrospective interviews. An ongoing debate is whether this phenomenon exists as a figment of memory or a true function of visual perception. Testing these speculations is difficult given slow-motion experience is often associated with intense, stressful, and even threatening situations that dramatically heighten arousal. Virtual reality systems might provide an opportunity to study the experience online, thus offering insights into the speculated mechanisms. This study explores the feasibility to induce heightened arousal and its possible implications on perceptual encoding of information. Participants were exposed to various situations designed to influence arousal as measured by heart rate, and an implicit memory task was used for each situation to test perceptual processing. This study did not reveal performance gains associated with increased physiological arousal.


The density for mixtures of ethylenediamine (EDA) and water at 0.2 MPa was measured with a vibrating tube densitometer in the temperature range of 283 K to 353 K at intervals of 10 K. The entire composition range was covered with intervals of molar fractions of 10 %. The excess volume has a minimum at a molar fraction of water of 59 %, corresponding to a maximum at 69 % in the departure from additivity in density. The variation with temperature in excess volume is small, but for density it is complex. The temperature dependence in density is well described by combining a Redlich-Kister model for excess volume without temperature dependent parameters with models for the pure component densities.


Abstract Despite many reported associations, the direct cause of neurodegeneration responsible for cognitive loss in Alzheimer's disease and some other common dementias is not known. The normal human plasma protein, serum amyloid P component, a constituent of all human fibrillar amyloid deposits and present on most neurofibrillary tangles, is cytotoxic for cerebral neurones in vitro and in experimental animals in vivo. The neocortical content of serum amyloid P component was immunoassayed in 157 subjects aged 65 or more with known dementia status at death, in the large scale, population-representative, brain donor cohort of the Cognitive Function and Ageing Study, which avoids the biases inherent in studies of predefined clinico-pathological groups. The serum amyloid P component values were significantly higher in individuals with dementia, independent of serum albumin content measured as a control for plasma in the cortex samples. The odds ratio for dementia at death in the high serum amyloid P component tertile was 5.24 (95% confidence interval 1.79–15.29) and was independent of Braak tangle stages and Thal amyloid-β phases of neuropathological severity. The strong and specific association of higher brain content of serum amyloid P component with dementia, independent of neuropathology, is consistent with a pathogenetic role in dementia.


Predicting potential cancer treatment side effects at time of prescription could decrease potential health risks and achieve better patient satisfaction. This paper presents a new approach, founded on evidence-based medical knowledge, using as much information and proof as possible to help a computer program to predict bladder cancer treatment side effects and support the oncologist's decision. This will help in deciding treatment options for patients with bladder malignancies. Bladder cancer knowledge is complex and requires simplification before any attempt to represent it in a formal or computerized manner. In this work we rely on the capabilities of OWL ontologies to seamlessly capture and conceptualize the required knowledge about this type of cancer and the underlying patient treatment process. Our ontology allows case-based reasoning to effectively predict treatment side effects for a given set of contextual information related to a specific medical case. The ontology is enriched with proofs and evidence collected from online biomedical research databases using "web crawlers". We have exclusively designed the crawler algorithm to search for the required knowledge based on a set of specified keywords. Results from the study presented 80.3% of real reported bladder cancer treatment side-effects prediction and were close to really occurring adverse events recorded within the collected test samples when applying the approach. Evidence-based medicine combined with semantic knowledge-based models is prominent in generating predictions related to possible health concerns. The integration of a diversity of knowledge and evidence into one single integrated knowledge-base could dramatically enhance the process of predicting treatment risks and side effects applied to bladder cancer oncotherapy.


Report presenting wind-tunnel tests made to determine the aerodynamic characteristics of a scale model of a high-speed bomber with a dual pusher propeller aft of the empennage. Some of the results discussed include longitudinal, lateral, and directional stability and control, the empennage design, and ground effects on the aerodynamic characteristics. The results indicate that this particular airplane has several advantages with regard to stability and control over the conventional-type single-engine airplane configuration.


The birth of the Low Countries is a thorny issue since the rise of history as an academic discipline in the nineteenth century, and the problem is likely to haunt historians for some time to come. From the eleventh century onwards, the patchwork of principalities that had emerged between France and the German Empire acquired a distinct cachet as most of these principalities became exceptionally urbanized. As Flanders, Brabant, Guelders, Holland, and so on were all fiercely independent, scholars all agree that the increasingly structural socio-economic integration of these urbanised regions did not automatically lead to political integration, even if the ruling dynasties of these principalities were prone to intermarry. Yet, this political integration did take shape in the fifteenth and early sixteenth centuries when a series of contingent factors – ranging from bankrupt princes to accidental deaths – allowed a collateral branch of the royal house of Valois to inherit, to purchase, or to conquer a lengthy string of principalities that eventually stretched from Frisia to the Franche-Comte. This article is part of the discussion forum 'Constructing and Deconstructing the 'State': the Case of the Low Countries'.


Clutches are widely utilized for not only implementing gear shifting but also transmitting power in hybrid electric vehicles (HEVs). During the driving mode transition in a P2-structure HEV, the coordination of between power sources, such as engine and electric motor, is realized by a hybrid clutch. Therefore, it is of great significance to establish a control strategy for the hybrid clutch ensure drivability and driving comfort. In this study, a physical model of the hybrid clutch and other relevant components in the hybrid system is established in MATLAB/Simulink firstly. Then, a model-based coordinated control strategy is developed for the hybrid clutch during the driving mode transition. The hydraulic oil filling and torque transferring characteristics of the hybrid clutch are mainly considered in the control strategy. Finally, the proposed control strategy is validated by simulation and the results show that the quality of driving mode transition is obviously improved.


The prior legislation placed strong emphasis on a case by case approach, with a secret register of agreements and with minimal penalties." The 1974 legislation, passed under the Labor Party government, takes a totally different philosophical approach to restrictive trade practices enforcement. Basically, restrictive trading practices are described in sweeping terms at times unmistakably similar to the United States Sherman Act and other U.S. legislative enactments. Penalties range up to $Aust. 250,000. Case by case evaluation is largely excluded from the legislation. Furthermore, the legislation includes a national coverage of false and misleading business conduct and provision for consumer warranties on goods. Previously these matters had been left to the parliaments of the respective states.


In this paper, the time series of hydrological processes analysed using ADF, KPSS, Mann-Kendall tests and linear time series models on monthly scale in the West Azerbaijan province of Iran. Significant decreasing trend in precipitation and stream flow discharge were observed. Also, non-stationarity in precipitation was observed in four studied basins. Decreasing stream flow discharge partially can be a result of trends in precipitation and evaporation. The population growth, land use changes and increase in water withdrawal are other reasons to blame. The results of linear time series modelling indicates that ARMA models for modelling stream flow only appears when precipitation or evaporation models have a MA component. On the other hand, when precipitation and evaporation models only have AR component, stream flow models are also follow autoregressive models and moving average components vanish. Moreover, in climatically homogenous basins, the same models were best-fitted for different hydrologic processes.


Forming limit is the most important formability index and process parameter in sheet metal forming.On the basis of the expatiation on the effects of forming limit to the research and application of sheet metal forming,this paper overviews and analyses the theoretical and experimental investigation progress on the forming limit.FLD is remarkabaly affected by the strain paths,which brings the inconvenience to industry.And the forming limit stress diagram which established with limit stress is independent on the strain paths and it is more convenient and practical to use as the criterion of forming limit under complex strain paths.Therefore,the research of the FLSD combined with FLD becomes the hotspot and one of main approachs to establish the limit criterion accurately.The cruciform biaxial tensile test is an effective and practical method to realize the process of complex strain paths.Finally,the pivotal question is expounded for the FLSD and the cruciform biaxial tensile test.


In this paper we discuss two-dimensional (2D) annular PC. In particular, we consider a finite size PC composed of an air-hole and dielectric rod array such that an air-hole is centered within each dielectric rod. The clusters we consider consist of parallel, disjoint two-layered cylinders of arbitrary shapes. We implement computational techniques and analyze the Green's function, using both the semi-analytical (for circular cylinders) and numerical-boundary element (for arbitrary cylinders) methods.


SARKAE – Modeling the Co-Evolution of Event Memory and Knowledge Angela B. Nelson (email@example.com) Department of Political Science, University of California San Diego, 9500 Gilman Dr. #0521 La Jolla, CA 92093 USA Richard M. Shiffrin (firstname.lastname@example.com) Department of Psychological & Brain Sciences, Indiana University, 1101 E. Tenth Street Bloomington, IN 47405 USA Abstract the context of the experimental setting, are added to the lexical representation of the word. When the studied word is then presented for perceptual identification, the context tends to be similar to that at study, increasing the match of the probe cues to the lexical trace, predicting a variety of measurable effects that match those observed. In other words, the knowledge that a subject has about a stimulus, and the inclusion in that knowledge of factors like the experimental context, affect the way that a stimulus is perceived. There are many models of the storage and retrieval of event memories, and sometimes the addition to existing knowledge of information from recent events (e.g. - Raaijmakers & Shiffrin, 1981, Shiffrin & Steyvers, 1997, Howard & Kahana, 2002, Anderson, 1983). The temporal context model of Howard & Kahana for example provides an explanation for recency and contiguity effects through the storage of both item information and recent contextual information. Other models, such as the ACT-R model of Anderson (1983) also provide eloquent representations of memory storage and retrieval. A few models attempt to explain aspects of the way events produce knowledge, especially for aspects of the role played by words in language (e.g. McClelland & Rumelhart, 1981). However, most of the prior research has been aimed to explain memory and learning when knowledge has already formed (to various degrees). Previous work by Reder et al. has examined the development of knowledge on a set of pseudowords, and used the dual-process SAC model to explain their findings. Although highly relevant and useful in the development of our research, the training study and modeling by Reder et al. did not explicitly model the growth of new knowledge. Our aim is the development of a model that begins to explain the interacting growth of event memory and knowledge, as they influence both memory storage and retrieval. This co-evolution of the two systems was the focus of the REM-II model, created by Mueller and Shiffrin (2006). In this model, knowledge (or semantic memory) is represented as an accumulation of the co-occurrence of features: Features that are present in an episodic event are coded as occurring together in a matrix representation of semantic memory. REM-II is a quite powerful model, but a simplified version is sufficient to explain the basic concepts We present an overview of a model for the co-evolution of knowledge and event memory. The model, termed SARKAE (Storing and Retrieving Knowledge and Events), describes the development of knowledge and event memories as an interactive process: knowledge is formed through the accrual of individual events, and the storage of an individual episode is dependent on prior knowledge. We reference two experiments which provide data to inform our theory: these studies involve the development of new knowledge, and then testing in transfer tasks involving episodic memory, retrieval from knowledge, and perception. The results of the transfer tasks indicate a substantial role of pure frequency or raw exposure, in opposition to the contextual diversity accounts of frequency suggested by Adelman et al (2006). An overview of the SARKAE model is presented. The model is able to account for the effects of frequency in the absence of contextual diversity. Keywords: episodic memory; semantic memory; learning; perception; Bayesian models. Introduction The processes involved in the accumulation of knowledge and the formation of event memories are interdependent. Almost every study since the 1890s has shown that the way episodic (or event) memories are encoded depends on the knowledge (or semantic memory) of the individual who is encoding them. Conversely, an individual's knowledge must be formed through the episodes they encounter; this idea was the basis of the REM model's account of priming (Shiffrin & Steyvers, 1997). These interdependent processes create a feedback loop in which knowledge and episodic memory formation develop together over lifelong learning. Studies of memory and perception in the recent past have provided strong support for the idea that memory processes are robustly influenced by prior experience with the to-be- remembered content. Priming studies, for example, have shown that prior study of a word affects how well that word is identified in a forced choice perceptual identification task (Ratcliff & McKoon, 1997). The REMI model of Schooler, Shiffrin, and Raaijmakers (2001) accounts for these effects through a process in which the lexical representation (or knowledge) of the word is changed through prior study (the "prime"); when a word is studied an event memory is formed, but in addition, novel features of the event, such as


Temperature-based snowmelt models are simple to implement and tend to give goodresults in gauged basins. The situation is, however, different in ungauged basins, as the lack ofdischarge data precludes the calibration of the snowmelt parameters. The main objective of thisstudy was therefore to assess alternative approaches. This study compares the performance oftwo temperature-based snowmelt models (with and without an additional radiation term) and twoenergy-balance models with different data requirements in 312 catchments in the US. It considersthe impact of: (i) the meteorological forcing, by using two gridded datasets (Livneh and MERRA-2),(ii) different approaches for calibrating the snowmelt parameters (an a priori approach and onebased on Snow Data Assimilation System (SNODAS), a remote sensing-based product) and (iii) theparameterization and structure of the hydrological model used for transforming the snowmelt signalinto streamflow at the basin outlet. The results show that energy-balance-based approaches achievethe best results, closely followed by the temperature-based model including a radiation term andcalibrated with SNODAS data. It is also seen that data availability and quality influence the rankingof the snowmelt models.


Military personnel use dietary supplements (DSs) for various reasons. Despite lack of evidence of effectiveness, safety concerns and increasing cost, Soldiers continue using DSs.


Jump random noises exist widely in control systems. In this paper, the guaranteed cost control problem for uncertain systems perturbed by jump random noises is considered. By adopting Poisson process to describe jump random noises, this paper utilize martingale theory to design a controller, which can stabilize such stochastic systems and guarantee the specified cost function has an upper bound.


Context. Over the next few years, ALMA and Herschel missions will perform high spatial and spectral resolution studies at infrared and sub-millimeter wavelengths. This will provide much greater detail about the composition and evolution of molecules in space. Modeling of the spectra will require accurate radiative and collisional rates for species of astrophysical interest. Aims. We calculate ro-vibrational excitation rate coefficients of SO by He, useful for studies of high-temperature environments. Methods. A new accurate three dimensional (3D) potential energy surface was calculated for the SO-He system which explicitly takes into account the r-dependence of the SO vibration as well as the R-distance and 6 angle which describe the relative position of the collision partners. The dynamics calculations were performed according to the VCC-IOS approximation. Results. The new rate coefficients between the ro-vibrational levels are calculated for temperatures from 300 K to 800 K.


A participatory multi-stakeholder process of finding options for improving livestock production in the severely degraded communal grazing area of Sterkspruit in South Africa was conducted. Interviews were conducted with individual livestock keepers from two sites to gather data on their demographic characteristics, livestock holdings, and main sources of income. Interviews and focus workshops with various stakeholders and the livestock keepers were conducted on what they perceived to be options for improving livestock production. Livestock keepers comprised less than 20% of the entire population in both villages, consisting of individuals about 60 years of age. About 60% kept less than eight cattle. Regardless of herd size, about 40% relied on old-age and welfare grants rather than livestock for income. Livestock keepers identified options promoting survival of livestock, such as improved veterinary services and winter feeding as a priority. In contrast, other stakeholders, including representatives of government, municipalities, farmers unions and commodity associations, identified options for reducing livestock numbers, such as marketing and removal of large stock owners to private land, as a priority for reducing degradation due to overstocking. Due to this difference in goals and aspirations, no common set of priorities could be agreed upon.


Vesignieite, Cu3Ba(VO4)2(OH)2, crystallizes in space group C2/ m with a ° = 1.0270(2), b ° =0.5911(1), c° = 0.7711(2)nm and β =116.42(3)°. The intensity data were collected with the RIGAKU RASA-IIS single-crystal four-circle diffractometer. The structure was determined by Patterson and Fourier methods and refined by the least-square technique to a final R index of 0.051 for 614 independent diffraction points with |F| > 3σ| F|.

The crystal structure analysis shows that vesignieite has a layer structure parallel to (001).

The powder diffraction lines were reindexed.


The lichen family Stereocaulaceae comprises four genera, Argopsis, Compsocladium, Pilophorus, and Stereocaulon (Jahns 1970). Formerly only species forming pseudopodetia were included in the family, but recently Purvis & James (1985) transferred two crustose species to Stereocaulon. In the present communication, the crustose species Lecidea pallida Th.Fr. is placed in Pilophorus. Lecidea pallida is an arctic-alpine, terricolous or saxicolous lichen which is recognized morphologically by its yellowish white areolae mixed with brown cephalodia and black, immarginate, strongly convex to hemispherical apothecia (Fig. 1). It belongs among the many species not assigned to any of the genera recently segregated from Lecidea s. lat. Cephalodia might indicate a relationship with Amygdalaria or Porpidia, but Lecidea pallida differs from taxa in these genera by having non-amyloid hymenial gelatine and subhymenial layers, and different types of exciple, paraphyses and asci. Lecidea pallida was described by Fries, who noted both the cephalodia and the non-amyloid hymenial gelatine (Fries 1860,1874). I believe that both these features indicate a relationship with the Stereocaulaceae, and, by comparing the apothecial anatomy of L. pallida with that of seven of the ten presently accepted species of Pilophorus (Jahns 1981), no differences relevant at the generic level were observed (pycnidia are unknown in L. pallida). Lecidea pallida has a proper exciple composed of radiating, thick-walled hyphae with thread-like lumina; a greenish black epithecium; a dark brown (often greenish brown in upper part) hypothecium which lacks a columnella; a non-amyloid hymenial gelatine; strongly conglutinated, thick-walled, straight, sparingly branched paraphyses; clavate asci surrounded by an amyloid sheet, having a well-developed, amyloid tholus containing a deeper amyloid central tube and frequently an ocular chamber; and simple, colourless, ellipsoid, rather large (16-22 x 6-9 (xm) ascospores. Cephalodia are either smooth and contain Nostoc, or are more granular and contain Stigonema; both types may be found in the same specimen. The thallus contains isousnic acid detected by the method of Culberson (1972). According to Jahns (1981), all species of Pilophorus contain atranorin and zeorin; some species may also contain additional substances. The identified additional substances are: stictic acid (in P. nigricaulis (Sato) Jahns and P. vegae Krog; Krog 1968), constictic acid (in P. nigricaulis; Kurokawa & Shibuichi 1970), and caperatic acid (in P. clavatus Th. Fr.; Kurokawa & Shibuichi 1970, as Pilophoron hallii). My t.l.c. examinations of the 10 species of Pilophorus, however, showed isousnic acid, and not atranorin, in all examined specimens of P. clavatus and in one specimen of P. curtulus (Kurok. & Shib.) Jahns (Table 1). Pilophorus clavatus also contained zeorin, some undetermined triterpenoids,


Step 1 To enable IKE for VPN connections: a) In ASDM, choose Configuration > Remote Access VPN > Network (Client) Access > AnyConnect Connection Profiles. b) In the Access Interfaces area, checkAllow Access under IPsec (IKEv2) Access for the interfaces you will use IKE on. Step 2 To enable IKE for Site-to-Site VPN: a) In ASDM, choose Configuration > Site-to-Site VPN > Connection Profiles. b) Select the interfaces you want to use IKEv1 and IKEv2 on.


Introduction : acute otitis media is a universal disease, represents the first cause of prescription of antibiotics in childhood. Objective : to characterize pediatric patients under 15 years hospitalized in the Respiratory service of the Bayamo Children's Hospital, during the year 2017, with diagnosis of acute otitis media. Methods : descriptive, longitudinal, prospective study. Universe: 333 patients, sample: 298, selected by simple random sampling. Variables studied: age, sex, risk factors, signs and symptoms, complications and treatment. Research methods used: theoretical, empirical and statistical. Results: the age group of 2 to 4 years (61.1%) and the masculine sex (58%) predominated; the most frequent risk factors were attendance at day care centers or nurseries (56.4%), the non-feeding with breastfeeding (34.2%) and the use of the pacifier (teat or bottle) (30.9%). The signs and symptoms present in the majority of the children were fever of 38 to 39 degrees (94.3%), preceded by a picture of rhinopharyngitis (100%). Perforation of the tympanic membrane (3.35%) was the only complication. The antibiotics of choice used were Trifamox® (bulbs) and amoxicillin (suspension and capsules) for 10 days. Conclusions: acute otitis media predominated in infants of the age group 2-4 years, of male sex, with the presence of risk factors, which evolved favorably with conventional treatment for 10 days, and only a small percentage of the series was complicated.


Supracondylar fracture of the femur after total knee arthroplasty is a serious complication and the management for this complication is controversial. We have experienced two cases using external fixation to treat this fracture. Both patients had osteopenia and we could not find surgical encroachment of the anterior femoral cortex. Activities of daily living of these patients returned to prefracture level following treatment.The external fexation allows early range-of-motion exercises at the knee without the need for prolonged bed rest and extensive surgical exposure. We concluded that this technique is useful for treating this fracture.


The mechanical system of quadruped robot were mostly rigidity at present.Taking the robot as a flexible body,it gave the virtual design of mechanical system and designed a kind of wheel mechanism.Firstly,the article proposed the scheme of the robot and design plan of the mechanical system.Then,the critical mechanisms were introduced.Especially,the wheel mechanism was introduced in detail.The control function of the spine bend and step were given by the theory analysis.The wheel mechanism cooperated with the stepped mechanism and realized the step control and wheel of the quadruped robot.


For a long period of time significant progress attained in in vitro embryo production. Despite desired levels has not been reached  the main reason are inability to imitate in vivo conditions of in vitro culture medium precisely and embryo be exposed to stress factors such as environmental conditions, temperature and biological components as a reaction produce stress proteins. Stress proteins which are increased in the organism during culture medium components, serums (FCS, ECS), UV rays, toxin, arsenic, pH, ischemia, oxidative phosphorylation, cold and hot conditions and during infections and vary in size between 100 to 8 kDA. HSP70 has two main domains, compact amino terminal site and low ATPase activity which been highly conserved and it regulate heat shock activity. During in vitro embryo production, the effect of environmental stress and embryo development processes in relation with the roll of HSP70 is very important. Presence of serum in the culture medium thought that it decreased the embryo development rate. In this review, we attempted to explain heat shock proteins and their varieties produced in vitro by oocyte maturation and embryo production. Furthermore, the possible effects of these proteins on in vitro embryo production activity have been discussed.


Lack of water resources in Iran, especially in recent years, has faced the agricultural sector as the most important consumer of water resources, with serious challenges. In Iran, the agricultural sector accounted for more than 90% of water consumption. However, the focus on domestic production and self-sufficiency policy in staples (wheat, barley, maize and rice) has been emphasized in general agriculture's policy. This study was conducted to estimate the imported virtual water from the imports of basic products in Iran using defined indicators during 1961-2013. Also this study investigated the possibility of achieving self-sufficiency due to the limited water resources in Iran. The results of this study showed with the increase in cereal imports, virtual water imports from 0.28 billion cubic meters in 1961 increased to 17.6 billion cubic meters in 2013 and on average about 60% of virtual water imports in strategic products is related to wheat imports during the past 53 years. Other products in cereal (barley, maize and rice) are also indicative of the general trend of increasing imports of virtual water in development plans. The estimated long-run elasticity of virtual water imports in the cereal group compared with the country's water resources also showed that with a one percent reduction in renewable water resources of the country, the virtual water import in the main cereal group will increase equivalent to 2.89 percent and the determination coefficient more than 90 percent also confirms this negative relationship. According to this result and the emphasis on the fact that renewable water resources per capita in the country is falling increasingly, it cannot be expected that domestic production could compensate for the imports of the cereal group and virtual water imports with current technology, without increasing the water productivity and without additional harm to water resources.


A new ligand based on permethylated β-cyclodextrin bearing a methylimidazole group was synthesized. In the presence of this N-heterocyclic carbene ligand, silver or palladium complexes were generated. Interestingly, palladium species based on this ligand are more active than palladium species based on TPP or IMes,Cl for a Suzuki cross-coupling reaction.


A hybrid automatic transmission system without an electric hydraulic pump is provided to fix an input shaft of an automatic transmission by mounting an one way clutch between the input shaft and a center support. A hybrid automatic transmission system without an electric hydraulic pump comprises a damper(24) mounted on an engine drive plate, a carrier(25) connected to the damper, a double pinion gear set(26) installed in the carrier, a clutch(27) connecting or disconnecting an electric motor(23) with an engine, the electric motor equipped with a ring gear(28), a stator(29) and a sun gear(30) and an one-way clutch(32) mounted between an input shaft(21) of an automatic transmission and a center support(31). The one-way clutch at the input shaft of an automatic transmission is locked and the engine operates clockwise through the electric motor rotating anticlockwise when the engine starts.


A new directional processing method of optical device of ZnGeP 2 crystal grown by Vertical Bridgman-Stockbarger technique has been studied.The direction of c axis of the crystal could be found fast according to the method that combines cleavage faces((112) and(101)),standard pole figures and X-ray diffraction,and then the(001) face can be determined.The light pass surface was got by phase matching angle,azimuth and faces(101) and(102).A semi-finished device of ZnGeP 2 optical parametric oscillator(OPO) was got by cutting this surface.Final ZGP-OPO device with size of 11 mm ×11 mm ×22 mm was obtained by X-ray diffraction on the sample,and subsequent polishing and coating process.Tunable midinfrared laser in the range of 3-5 μm was realized on the ZGP-OPO pumped by 2.1 μm,7 kHz laser,and the output power reached 0.48 W.The method not only could be used on orientional processing of ZnGeP 2, but also could be applied on orientional processing of other crystals with the similar structure.


Hydrogen sulfide (H2S) concentration and emission at a modern mechanically ventilated swine finishing building
with a deep pit were continuously measured for three summer months. Ventilation rates, temperatures, and pig inventory in
the building were also continuously measured or recorded. A total of 88 d of valid data were obtained between 26 June and
25 September, during which the average daily mean (ADM) ambient temperature was 21.8  C. The test began with 887, 19–kg
pigs in the building and ended with 874, 83–kg pigs. Hydrogen sulfide was measured with a sulfur dioxide (SO2) analyzer
equipped with a thermal oxidizer that converted H2S to SO2. Building ventilation rates were determined by continuously
monitoring exhaust fan operation and differential static pressure. Daily mean building H2S concentrations ranged from 38
to 536 ppb. The ADM building concentration (average of three locations) was 173  21 ppb (mean  95% confidence interval).
The maximum concentration, averaged over 7– or 12–min sampling periods, was 1,624 ppb. The 25 th , 50 th (median), and 75 th
percentile values were 413, 527, and 662 g/d for daily mean building H2S emission and 4.4, 5.8, and 12.4 g d –1 AU –1 (animal
unit = 500 kg live mass present in the building) for daily mean specific emission, respectively. These H2S emissions were much
greater than emissions measured or estimated in previous studies. Based on daily means, H2S concentration was inversely
proportional (P < 0.05) to ventilation rate (r = –0.68), whereas building H2S emission was influenced somewhat (P < 0.05)
by building temperature (r = 0.29) and ventilation rate (r = 0.23).


It describes a method and system for controlling potentially harmful for transmitting voice signals in the. The method comprising the steps of: establishing a signal when the signal characteristic of the speech transmitted when; monitoring said signal; and a characteristic with respect to the established to control the signal.


FIELD: chemistry. SUBSTANCE: invention relates to moisture-cured hot-melt adhesives. Disclosed is a moisture-cured hot-melt adhesive composition containing at least one silane group-containing polyurethane prepolymer of formula (I), where R 1 is an n-valent organic radical of prepolymer P, which is obtained from at least one polyol and at least one polyisocyanate and has at least n isocyanate groups, followed by removal of the n isocyanate groups; R 2 is a C 1 -C 10 alkyl group; R 3 is a linear or branched C 1 -C 10 alkylene group; X is a hydrolysable radical OR 4 , wherein R 4 is a C 1 -C 10 alkyl group which can contain 1 or 2 oxygen atoms of an ether; a equals 0, 1 or 2; n equals 2 or more; where the prepolymer of formula (I) is obtained from reaction of the polyurethane prepolymer P with a mercaptosilane of formula (II), wherein the prepolymer P is solid at room temperature and does not have an additional silane group, and the composition has longer storage life (viscosity stability) in uncured form. Disclosed also is a method for adhesive binding of substrates using the disclosed adhesive composition and an article obtained using the adhesive. EFFECT: disclosed adhesive compositions do not form bubbles neither when heated nor during curing and have stable viscosity at high temperatures. 20 cl, 7 tbl


Librarians in there relations with there customers and with other librarians have to establish good relations. Librarians work long hours and it is somewhat monotonous. Librarians are also busy with a collateral work while working as a librarian. Working together busy sincere, warm relations among managers and working personnel. University libraries are integral part of every university and they have to meet the demands of students in thousands. The aim of this article is to find out the effects of stress on university librarians working in Northern Cyprus as useful human resources, and propose certain strategies to create a good environment for the librarians to work effectively and with endless determination in their jobs. Also research article about job stress improvements related to business administrative in introduction.


Resumen en: The objective of the study was to compare three cases of biodiesel production from microalgae dried biomass applying the Life Cycle Assessment (LCA) tech...


The drug evaluation process engages many different groups in society: the pharmaceutical company developing the drug, the national drug agency, international authorities such as the European Medicines Agency and the US Food and Drug Administration, committees for establishing national drug treatment guidelines, drug selection committees, the prescribing physician, and finally, the patient are those directly involved. Indirect actions and opinions are put forward by pharmacists, nurses, media, lawyers, politicians and patients' relatives and friends. Judgments and opinions will coincide for several of these actors but there might also be total contradiction in the final conclusion from some of them. Who is right … and who is wrong? All can be judged to be right from their perspectives. A physician may be negative about a certain drug in the drug formulary committee but then prescribe the same drug some hours later for a patient not responding …

Correspondence to Professor Per Hartvig Honore, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen 2100, Denmark; peh{at}sund.ku.dk


We study $p$-divisible groups $G$ endowed with an action of the ring of integers of a finite (possibly ramified) extension of $\mathbb{Q}_p$ over a scheme of characteristic $p$. We suppose moreover that the $p$-divisible group $G$ satisfies the Pappas-Rapoport condition for a certain datum $\mu$ ; this condition consists in a filtration on the sheaf of differentials $\omega_G$ satisfying certain properties. Over a perfect field, we define the Hodge and Newton polygons for such $p$-divisible groups, normalized with the action. We show that the Newton polygon lies above the Hodge polygon, itself lying above a certain polygon depending on the datum $\mu$. We then construct Hasse invariants for such $p$-divisible groups over an arbitrary base scheme of characteristic $p$. We prove that the total Hasse invariant is non-zero if and only if the $p$-divisible group is $\mu$-ordinary, i.e. if its Newton polygon is minimal. Finally, we study the properties of $\mu$-ordinary $p$-divisible groups. The construction of the Hasse invariants can in particular be applied to special fibers of PEL Shimura varieties models as constructed by Pappas and Rapoport.


First of all,this paper analyses the working principle of increasing the bearing capacity of the piles in post-grouting and then presents an engineering example for successively treating the weak intercalated layers in the ends of piles by using the technique.In conclusion,it shows that the bearing of piles can be significantly increased by applying the post grouting technique in the ends of piles,but the increments need testing by field monitoring.


Objective : Audio-evoked potential is technique used for measuring brain functions such as memory, attention, and concentration. Although a number of studies on acupuncture for pain, there are few reports on the effect of acupuncture cognitive function. Methods : Fifteen healthy volunteers with no neurological condition took part of the study. . In this study, we examined the changes in auditory P300 by acupuncture stimulation to 'Oegwan' on the left hand. Auditory P300 was recorded before, during and after acupuncture. The amplitude and latency of P300 at Fz, Cz, Pz point were calculated. Results : Auditory P300 amplitude decreased during and after acupuncture, but there was no statistical significance.(P


Key Points Question Is a greater hospital-level tendency to admit older patients with rib fractures as an isolated injury to the intensive care unit (ICU) associated with improved outcomes for those patients? Findings In this cohort study of 23 951 patients aged 65 years and older, ICU use per trauma center varied from 0% to 92% of patients with isolated rib fractures. Greater ICU use was associated with a reduction in a composite adverse outcome of death, unplanned intubation, or pneumonia. Meaning These findings suggest that admission to an ICU may improve the outcomes of older patients with isolated chest wall injuries.


This paper aims to study the relationship between teamwork competences and successful innovative projects. Empirical insights are provided on this relationship from a study carried out at the School of Mining and Energy Engineering (UPM) in Madrid (Spain). The results of this study establish a strong connection between teamwork and innovative projects using Hierarchical (AHP) and statistical analysis. Throughout this article, the study of successful innovative projects and specifically the role that work teams play in them is proposed to build a model for the creation of work teams that serves as a tool to develop innovative projects of success. The final motivation of this line of research is that if the aspects that define successful innovative projects are known, the model can be fed with the characteristics that these projects include, predict and even prioritize in a portfolio of projects the allocation of resources that will be necessary. The deepening of work teams allows establishing a relationship between successful innovative projects and the composition of these teams, thus being able to propose a team-building model as a diagnostic and planning tool for innovation projects.
As a whole, the paper highlights the importance of team composition and development in order to achieve success in innovative projects.


Software systems are increasingly used to support business processes and knowledge workflows within critical areas, including transportation, finance, healthcare and government. The support for such processes, which are at the same time unpredictable and subject to changing legal constraints, calls for flexibility, adaptability and compliancy. In this talk we will present theory and applications of Dynamic Condition Response (DCR) graphs, a formal declarative event-based process language implemented in the commercial web-tool DCRGraphs.net for collaborative process design and simulation and the academic tools dcr.itu.dk. The language and tools are the result of a series of research and PhD projects supported by the danish national research foundations, ITU and Exformatics A/S and the ongoing Computational Artefacts (CompArt.ku.dk) project supported by the Velux foundation.


and operated an electromagnetic seismograph on Vesuvius in 1856. During the past decade, in particular, enormous advances have been made in both the theory and practice of seismic surveillance. The increasing utilization of digital broad-band and 3-component seismographs, aided by improved signal processing and a better understanding of seismic wave propagation, has led to greater precision and accuracy in locating and interpreting volcanic earthquakes. At the same time, increasingly dense seismic networks, in combination with advanced data processing, have contributed to the development of seismic tomographic techniques with the capability of revealing and interpreting the threedimensional form of sub-volcanic structures such as magma reservoirs. Such recent advances in volcanic seismology were addressed at a workshop in Capri (Italy) in 1988, and a selection of the papers presented form the basis of this book. There are 33 contributions in total, most of which sit easily within one of four categories: seismic activity and other precursors of eruptions; modelling of volcanic earthquakes, tremors and long-period events; tomography and detection of magma chambers; and seismic activity in resurgent calderas and geothermal fields. As might be expected, and with few exceptions, a case-study approach is adopted, with aspects of volcanic seismicity being considered at a range of active volcanoes and resurgent calderas. It is somewhat unfortunate that there is a strong regional bias, with most papers relating to Europe and the Americas, and a relative dearth of chapters concerning Asian volcanoes. Presumably this is an unavoidable result of a volume based solely on participation at a single, European-based, meeting. Although many of the included papers are admirable, and have general, as well as local, application to the seismic monitoring of volcanoes, the book might have been improved from the reader's point of view by the inclusion of relevent review chapters at the start of each of the four sections. These are minor deficiencies, however, and should not detract from the fact that this book currently constitutes the definitive text on volcanic seismology, and should be a compulsory purchase for all professional volcanologists and seismologists. It is also to be hoped that the price tag does not place this excellent text out of the reach of interested postgraduates.


was also considered, as this may induce neuropraxia of the parasympathetic fibres from the ciliary ganglion [5]. In one case report of unilateral mydriasis identified postoperatively, the patient underwent computed tomography, magnetic resonance imaging and angiography of the head and neck [6]. No pathology was identified and the pupils spontaneously recovered after three hours. Neuro-imaging the anaesthetised patient is not without risk: computed tomography involves a high radiation dose; magnetic resonance imaging in the presence of an intracranial metallic foreign body could be catastrophic; and there are risks associated with transferring patients to and from the radiology department. Clearly, it may be justifiable to undertake emergency imaging in certain cases, but only when necessary and in the best interests of an unconscious patient. Postoperative ophthalmic assessment of our patient demonstrated a dilated pupil reactive to accommodation but not light, confirmed to be a longstanding Holmes-Adie pupil. Pre-operative awareness of this information would have avoided significant concern and clinical input peri-operatively in this case. We strongly recommend that a simple pupillary examination becomes part of the routine pre-operative anaesthetic assessment.


: Although rarely, echinococcosis might present cardiac involvement, with cysts growing inside myocardial structures of arising adjacent to heart. A careful differential diagnosis with other mass formations and rare cardiac tumours is necessary, whenever there is a clinical and radiological suspicion. Imaging studies and serology will establish diagnosis. A multidisciplinary approach is warranted in all cases, with surgical intervention being unavoidable in most settings. Patients gen-erally present with chest pain and dyspnoea. Cases need a close follow up of their postoperative course, while being treated appropriately with albendazole (or mebendazole) for prevention of re-currences.


The relationship of the thoughts of Ming Dynasty's Philosophy(Hsin hsueh) and The Pilgrimage Towards the West has been recognized by the scholars widely,but there is seldom study on the communication of Wu cheng'en and the Hsin hsueh's schoolars,the influence of the Hsin hsueh on the Wu Cheng'en's mentality and composition.On the base of Song Kefu's reasearch,this thesis will study on the communication of Wu cheng'en and Hu Zongxian,and the indirect communication of Wu cheng'en and the Hsin hsueh's schoolars,such like Qian Dehong,Luo Hongxian,Tang Shunzhi,etc.


: Final summary report on solved test cases: Each solution of a test case will be evaluated during the validation workshops by running extensive tests with multiple data sets. On average we expect as a minimum three tests with different data sets per test case. After each round of testing the participants/testers will report problems and make suggestions for improvements. Once the solution for a test case is accepted by each test case community, and WP5 members together with the test case community will formulate an extensive report. At the end of the project WP5 will ensure that all solved test cases will be published correctly on the AllBio portal including optional software packages and test data sets, so that everybody can benefit from the AllBio results. Background: For most organisms, even if their genome sequence is available, little functional information about individual genes or proteins exists. Several annotation pipelines have been developed for functional analysis based on sequence, 'omics', and literature data. However, researchers encounter little guidance on how well they perform. TC12 requested the functional annotathin and therefor the recently sequenced potato genome was used as the case study. The potato genome is newly sequenced and it is a non-model plant even if there is relatively ample information on individual potato genes, and multiple gene expression profiles are available. Results: The solved TC shows that the automatic gene annotations of potato have low accuracy when compared to a "gold standard" based on experimentally validated potato genes. Furthermore, the TC evaluated six state-of-the-art annotation pipelines and showed that their predictions are markedly dissimilar (verified by the Jaccard similarity coefficient showing an average of lower than 0.3 between the different pipelines). To overcome this discrepancy, The TC introduced a simple GO structure-based algorithm that reconciles the predictions of the different pipelines. It shows that the integrated annotation covers more genes, increases by over 50% the number of highly co-expressed GO processes, and obtains much higher agreement with the gold standard.


This research was conducted for two months from April 2015 to June 2015 in Langkat District, known as one of the centers of the wood processing industry in North Sumatra. The object of research is entrepreneurs in wood industry companies in the study area. Based on the problems that have been formulated, the study aims to: (1) Analyze the effect of working capital variables, wood raw materials, labor costs and productivity in the wood processing industry on labor absorption in Langkat Regency. (2) Analyzing the average size of processed wood production produced by companies in Langkat Regency. (3) Analyzing the amount of the average absorption of labor per month received by the company in Langkat Regency. The study area was determined purposively with a sample size and population of 25 companies. Sampling of respondents using simple random sampling. The data used are primary data and secondary data. To examine the relationship between income and production costs the multiple linear regression analysis model is used. The results of this study indicate that the variable amount of working capital, wood raw materials, labor wages and productivity in the wood processing industry on labor absorption in Langkat District is 374 people with an average of 15 people, the average size of processed wood production produced the company in Langkat Regency is 282,429 m3. And the average absorption of labor per month received by the company in Langkat Regency is 15 people.


PurposeThe authors investigated the effect of basic human values in the prediction of COVID-19 vaccination behavior amongst public security agents in Brazil.Design/methodology/approachA sample of 15,313 Brazilian public security agents responded to the portrait values questionnaire and a COVID vaccination behavior measure. Multidimensional scaling analysis (MDS) was used to observe the order of the predicted by the theory. For hypotheses, the authors ran a series of Structural equation modeling (SEM) with direct effects between values and vaccination rate.FindingsResults suggest that the values of conservation and self-transcendence positively predicted vaccination. A nonsignificative negative prediction was obtained for openness to change and self-enhancement values on vaccination behavior.Research limitations/implicationsData were collected using self-report questionnaires.Practical implicationsInstitutional management should encourage capacitation campaigns aimed at public security agents, enabling a significant increase in vaccine protection for the public security institutions.Social implicationsThe reinforcement of conservation and self-transcendence values lead to the perception of the vaccine as a measure of caring for people in general and for the members of the ingroup, hence motivating the vaccination behavior.Originality/valueThe findings confirm that values encourage individuals to be vaccinated, due to their intrinsic motivation. This relationship did not appear to be clearly tested by previous empirical studies.


The invention discloses a full mold casting coating curtain coating device which comprises a coating supply device, a spray gun connected with the coating supply device and a curtain coating pool used for accommodating a blank die cast. The curtain coating pool comprises a base and a surrounding plate vertically arranged on the base. The base is provided with a storing face used for storing the blank die cast and an inclined flow guide face which is connected to the edge of the storing face. According to the full mold casting coating curtain coating device, the coating supply device and the spray gun are combined to spray coating on the surface of the blank die cast in the curtain coating pool, manual painting is replaced, so that work efficiency of coating the blank die cast is improved, time and labor are saved, and labor intensity is lowered.


Effects of interface roughness on the threshold-voltage variation of nanometer-size gate-all-around (GAA) and double-gate (DG) metal–oxide–semiconductor field-effect transistors (MOSFETs) are investigated using three-dimensional non-equilibrium Green's function formalism. It is found that DG MOSFETs have better robustness to the interface roughness compared to GAA MOSFETs. This is attributed to the fact that the GAA structure has additional quantum conferment along the gate-width direction of the DG structure. From numerical simulations, a simple analytical formula is derived, which describes the threshold-voltage variation in terms of the subband energy change and reduction in the transmission function.


As the thermoelectric coupling self-powering of a wireless sensor has a lower power and a fluctuated voltage,this paper proposes a new Power Management System(PMS)and its optimal time control strategy to allow the self-power wireless sensor to work stably at different spindle speeds.A thermal network model for the tool spindle was established and the input characteristics of thermal generating power management system was analyzed.Then,a circuit topology with more capacitances for the power management system was designed,and the optimized average output power from thermal generating power was obtained by calculating the charging/discharging time parameters of capacitors.An experiment was performed,and it verifies that the wireless sensor works stably atdifferent spindle speeds driven by thermal power generation devices and the power management system.Several schemes for setting charging/discharging time of capacitors were compared,and the superiority of the time control strategy was verified.Finally,the spindle axial thermal deformation models were established for the data from the thermoelectric coupling self-powering wireless sensor and the traditional wired sensor.The results indicate that the wireless sensor monitors the key part of the spindle that the traditional ones can not be installed in,by which the more directional temperature data relative to the thermal deformation of prediction are obtained,and the error of thermal deformation prediction model is deceased about 40%.


Searching for inhibitors in culture filtrate of microbes, we discovered many substances which specifically inhibit various enzymes such as serine-, cysteine-, aspartic-, and metal-proteinases, aminopeptidases, dipeptidyl aminopeptidases, carboxypeptidases, dipeptidyl carboxypeptidases, and so forth. These inhibitors have low-molecular-weights and uniquie structures. We found significant activities of exopeptidases, such as aminopeptidases, carboxypeptidases, alkaline phosphatase, esterase, and so forth, on surface membranes of various mammalian cells


A natural continuation from conventional convex methods for image enhancement is the transition to non-convex formulations. However, strictly non-convex models do not admit traditional tools from convex optimization to be used. To resolve this drawback, non-convex problems are often cast into convex formulations by relaxing stringent assumptions on model properties. In this work we present an alternative approach. We study when an energy functional is convex given a non-convex penalty term. Key to our formulation is the introduction of a novel coupling between the discretization scheme and a non-local weight function in the data term. We interpret the non-local weights for the finite difference operators. In a denoising application we study a class of non-convex ℓp-norms. The resulting energies are globally minimized using the popular ADMM.


The diagnosis and treatment of periprosthetic joint infection (PJI) remains challenging and, with a current reported rate of 0.7%, is an ever-increasing burden on the NHS. Although some patients present with clear evidence of infection, many present insidiously. Techniques to improve the diagnosis of PJI are being developed constantly, including the use of biomarkers. Positive periprosthetic cultures are a diagnostic criterion for PJI, with a consensus on three to six distinct intraoperative samples collected from the joint interface for analysis. As PJIs are associated with biofilm bacterial growth and acute planktonic phases, deep canal sampling should aid microbiological diagnosis, as the canal provides a finite space for bacterial proliferation.


Stones in the common duct are associated with increased risks of complications and death. Consequently, they need to be removed. The risk of gallstone formation rises markedly with the use of estrogen and clofibrate. Bacterial stains and plasmid used in this work was S. salivarius and S. feacalis. The bile salt tolerance to test the bacterial growth tolerance. Also, antibiotic tolerance was made to test bacterial growth tolerance. The extraction of plasmid PMG36bsh vector uses ethanol 96%. Total RNA extraction was made then cDNA synthesis with PCR machine. The fragmentation of gallbladder stones in S. feacalis broth media. The using of PMG36bsh vector carry bsh gene to get duplicate bsh gene expression in S. feacalis probiotic strain and became suitable drug to remove gallbladder stones. Tolerance to bile salt genes allows probiotic bacteria to survive in the small intestine. Total RNA expression levels of bacteria S. feacalis which show in control of S. feacalis total RNA conc. was 35.3ng/μl and cDNA conc.77.6 ng/μl. In wild type 97.7 ng/μl and 197.6ng/μl in S. feacalis (transformer type) 140.6 ng/μl and 237 ng/μl. Also the gall bladder reducing concentration and reducing ratio, which show in wild type bacterial with stone, bile salt and free cholesterol, the gallstone conc. 0.814 g/l in transformer type bacterial with stone, bile salt 0.748g/l. The bacterial modification can become principal noninvasive non-surgical treatment for cholesterol gallstones before and after treatment.


In this contribution, we review the time-dependent generalized-active-space configuration interaction (TD-GAS-CI) approach to the photoionization dynamics of atoms and molecules including electron correlation effects. It is based on the configuration interaction (CI) expansion of the many-body wave function and the restriction of the determinantal space to a reduced subspace. For its numerically efficient application to photoionization, a partially-rotated basis set is used which adopts features of a localized basis with a good reference description and a grid representation for escaping wave packets. After reviewing earlier applications of the theory, we address the strong-field ionization of a one-dimensional model of the four-electron LiH molecule using TD-GAS-CI and demonstrate the importance of electron-electron correlations in the ionization yield for different orientations of the molecule w.r.t the peak of the linearly polarized laser field. A pronounced orientation-dependent variation of the yield with the pulse duration and the level of considered electron-electron correlations is observed.


Henrik Ibsen's play Peer Gynt digs deep into the question of what it means to be oneself. An upcoming computer game version invites players to take on the role of Peer and thereby raises new questions about identity and identification. By recording dyads of students who play an early version of the game and analysing their interaction during gameplay, we examine how students collaboratively make meaning of the computer game. This study employs a sociocultural and dialogic approach to meaning making. In the analysis, we draw on Gee's theory on multiple player identities and see the dyads playing together as two real-world selves negotiating on creating one virtual self through a co-authorship of situated meaning in what Gee calls the projective stance. To better understand their cooperation in this undertaking, we also apply Goffman's term activity frames. The analysis shows how the dyads approach the game in different ways by establishing frames in which they interpret, impersonate or recreate Peer, in order to make meaning of their gameplay.


This research aims to determine the factors that affect the amount of imported goods intra-ASEAN. Factors influencing the import of goods in this study are Gross Domestic Product (GDP), Inflation and Exchange Rate in each member country of ASEAN. The method used in this research is panel regression through Panel Least Square (PLS) by using program Eviews 10. The data used is panel data, consisting of ten ASEAN member countries and ten years of research from 2006 to 2015. The results of the analysis data show that GDP and inflation have a positive and significant effect on the imported goods intra-ASEAN, while the exchange rate has a negative and significant effect on the imported goods intra-ASEAN. Simultaneously, GDP, inflation and exchange rate have a positive and significant effect on imported goods intra-ASEAN.


This article attempts to discuss from the poetry embryology, to inquire about characteristics of the related information dissemination in the process of studying poetry literary style and poetry development, to clarify the relationship between the development and dissemination of poetry. As a result, it can offer new train of thought for understanding and solving some problems existing in the poetry. Key words: poetry, poetry embryology, dissemination Resume: Le present article tente de chercher, sous l'angle de l'embryologie de la poesie, les caracteristiques communicatives du genre poetique dans son apparition et developpement et illustre la relation entre le developpement de la poesie et la communication, dans le but d'offrir de nouvelles perspectives a pas mal de problemes dans la comprehension de la poesie. Mots-Cles: poesie, embryologie de la poesie, communication


According to the World Health Organization, breast cancer is the most common cancer among women worldwide, claiming the lives of hundreds of thousands of women each year. Near infrared diffuse optical tomography (DOT) has demonstrated a great potential as an adjunct modality for differentiation of malignant and benign breast lesions and for monitoring treatment response of patients with locally advanced breast cancers. The path toward commercialization of DOT techniques depends upon the improvement of robustness and user-friendliness of this technique in hardware and software. In the past, our group have developed three frequency domain prototype systems which were used in several clinical studies. In this study, we introduce our newly under development US-guided DOT system which is being improved in terms of size, robustness and user friendliness by several custom electronic and mechanical design. A new and robust probe designed to reduce preparation time in clinical process. The processing procedure, data selection and user interface software also updated. With all these improvements, our new system is more robust and accurate which is one step closer to commercialization and wide use of this technology in clinical settings. This system is aimed to be used by minimally trained user in the clinical settings with robust performance. The system performance has been tested in the phantom experiment and initial results are demonstrated in this study. We are currently working on finalizing this system and do further testing to validate the performance of this system. We are aiming toward use of this system in clinical setting for patients with breast cancer.


With the rapid development of the society,polity,economy and culture,the ability of decision-making has become an important criterion to measure the talents needed nowadays,and thinking ability to make decisions is an essential component of it.This paper mainly explain the concept and characteristics of decision-making thinking and policy-decision at first,and then combining with the characteristics of physics teaching in the middle school,the students'thinking ability of making decision is cultivated effectively through three methods.


7110 Background: The Jak2-V617F mutation is frequently found in MPN. The bone marrow micro-environment of MPN patients constitutes high levels of TNFα, IFNγ and IL-6. Since resistance to drug agent...


of Dissertation Presented to the Graduate Council of the University of Florida in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy REASON AND THE UNITY OF EXPERIENCE: NIETZSCHE'S CRITIQUE OF TRADITIONAL CONCEPTIONS OF TOTALITY


The substantive story of Gaston Leroux's The Phantom of the Opera (Le Fantome de l'Opera) is largely about contract analysis and whether the managers and "the phantom" have had a "meeting of the minds"—consensus ad idem.

The question is whether the Phantom and the Managers reached a "meeting of the minds" or manifested mutual assent in their contractual remedies. In the end, there was no contract and the managers could have claimed significant losses directly through their contractual terms with the Phantom.


Review(s) of: Global Citizenship Education: Philosophy, Theory and Pedagogy, Michael A Peteres, Alan Britton and Harry Blee (EDS.) 2008 Rotterdam: Sense Publishers, 533 pp


The invention discloses a fuzzy control system of a hot wind drier used for adjusting the hot wind temperature of hot wind drier. The system comprises a feedback module, a servo module and a control module; the control module is used for receiving a given temperature value and the actual temperature value of the hot wind collected by the feedback module and output by the drier; both values are compared to obtain a deviation value; the derivation of the deviation value is carried out to obtain a derivation value derivation; after the fuzzy treatments of the derivation value and the derivation value derivation are carried out, a preset control decision table is searched to obtain a mapping control quantity; and the mapping control quantity is sent to the servo module as a control signal for adjusting the temperature of hot wind output by the drier. The system adjusts the hot wind temperature of hot wind drier, and can be applied to the devices such as timber drier and gypsum board drier.


The present invention includes i) a step of preparing a raw material mixture containing metallic Ni powder, ii) a step of pelletizing the obtained mixture, iii) a step of burning the raw pellets, and iv) the combustion pellets And reducing the iron ore pellets under reducing conditions in the presence of CH 4 .


Four kinds of new aliphatic diols were synthesized by the ring opening reaction of glycolide with 1,4-butanediol, 1,6-hexanediol, 1,4-cyclohexanediol, or 1,4-cyclohexanedimethanol, a difunctional initiator, in the presence of stannous octoate catalyst. The resulting diols were melt-polymerized with succinic acid, adipic acid, or suberic acid at 170, 190, or to produce new sequentially ordered aliphatic polyesters and their corresponding polyesters with random structure. Their glass transition temperatures () ranged from -40 to , The sequentially ordered polyesters prepared at had higher of 5 to than the polyesters with rand()m structure produced at higher temperature. From in-vitro degradation test the sequentially ordered polyesters was shower in the rate of hydrolysis in a buffer solution than the polymers with random molecular structure


Objective To study the clinical effect and safety of laser corneal operation and intraocular refractive operation for the correction of high myopia.Methods 74 cases with super high myopia patients who received various refractive operation in our hospital,totally 108 eyes,were randomly divided into A,B,C three groups,36 eyes in each group.Patients in group A undergoned LASIK treatment;group B patients with transparent lens phacoemulsification extraction combined with posterior posterior chamber intraocular lens implantation;group C with phakic iris fixated intraocular lens implantation,postoperative indicators statistical comparison.Results After treatment,the visual acuity of the three groups improved obviously,the post operative diopter of A,B,C were(-2.10±2.38)D,(1.75±1.33)D and(0.83±1.16)D respectively.Conclusion For super high myopia patients,lens refractive operation effect was superior to that of the LASIK patients,but also for super high myopia patients should be based on the patients' age and eye conditions for specific operation plan.


Scholastic Success Among Girls: Two Contradictory Readings Pierrette Bouchard and Jean-Claude St-Amant Chair of the Claire-Bonenfant Study on the Condition of Women Université Laval, Canada In the past, access to education was at the centre of many collective claims made by the women's movement. Today the scholastic success of girls is one of the most remarkable results of this. In the Québec context, the study of family dynamics shows how "day-to-day feminism" is the primary reason for this success. However, for the past ten years or so, a masculinist counter-discourse has appeared in the media, focussed on "the scholastic difficulties of boys", inspiring a large variety of school projects. The analysis shows that these interventions are designed from essentialist and naturalizing ideas about masculine identity. Moreover, the inefficient scholastic performance of boys reveals that they have a completely different agenda: to recover their lost masculine privileges. Thus, education is at stake in the social relationships between the sexes, where they battle for the places they will hold in tomorrow's society.


People usually spend several hours per day inside buildings, and they require great amounts of energy and resources to operate. Although there are numerous studies about smart buildings, there is still a need for new intelligent techniques for efficient smart building management. This paper proposes the use of Wi-Fi network association information as a basis for the design of intelligent systems for smart buildings. We propose a unified experimental methodology to evaluate machine learning (ML) models on their capacity to accurately predict Wi-Fi access point demand for energy-efficient smart buildings. The evaluation involves the use of multiple classification and regression models using a variety of configurations and algorithms. We conducted an experimental analysis using our proposed methodology to determine which ML models provide the best performance results using data collected from a large scale Wi-Fi network located at Fluminense Federal University (UFF) over a period of 6 months. The proposed methodology enables the user to evaluate and to create ML models for energy efficient smart building management systems. We achieved 86.69% accuracy for occupancy prediction using classification techniques and RMSPE (Root Mean Squared Percentage Error) of 0.29 for occupancy count prediction using regression techniques.


Aluminium alloy castings, which can be not only manufactured in larger geometrically complex shapes, but also show good mechanical properties in addition to light weight, have kept their potential use as structures in the field of automotives, industrial machines and aircrafts. The variations of eutectic Si size a great effect on the elongation, impact value, fracture toughness and fatigue crack propagation rate without changes in the tensile strength or yield strength. The cooling curves with the solidification rate between and were obtained. With the increase of solidification rate, DAS, eutectic Si size and grain size were all decreased, which enhanced the mechanical properties. The tensile strength and yield strength were the most greatly influenced by DAS, and the elongation and impact value by eutectic Si size.


An ideal plasma lens can provide the focusing power of a small f-number, solid-state focusing optic at a fraction of the diameter. An ideal plasma lens, however, relies on a steady-state, linear laser pulse-plasma interaction. Ultrashort multi-petawatt (MPW) pulses possess broad bandwidths and extreme intensities, and, as a result, their interaction with the plasma lens is neither steady state nor linear. Here, we examine nonlinear and time-dependent modifications to plasma lens focusing, and show that these result in chromatic and phase aberrations and amplitude distortion. We find that a plasma lens can provide enhanced focusing for 30 fs pulses with peak power up to ∼1 PW. The performance degrades through the MPW regime, until finally a focusing penalty is incurred at ∼10 PW.


absence of arylcarbinol groups and may be taken to indicate a large number of C-C bonds between the phenylpropane units, of the artificial lignin. In view of the readiness with which eugenol forms dehydrodieugenol (II) it might be suspected that a large number of diphenyl links would occur in eugenol lignin, but the low yield of dehydrodivanillin (III) shows that this is not the case. Despite similarities of the eugenol lignin to gymnosperm lignin it does differ from natural lignin in the very important aspects mentioned above and certainly cannot be accepted as a true lignin. This should emphasize the danger of drawing conclusions about natural lignification from experiments in artificial systems.


Abstract It has been shown that low size dispersion systems of carbon nanoclusters can be fabricated by ion irradiation of fullerite C60 film through a special mask. As the mask, lavsan track membrane with more or less equal pinholes of diameter of about 60 nm was used. STM study showed that fabricated clusters have a form of the cone‐like island with average diameter of about 60 nm and height of about 5 nm.


Based on the data of several trials the Totaled Health Risks in Vascular Events (THRIVE) score has been shown to predict outcome after either intravenous thrombolysis (IVT) or endovascular therapy (ET) in acute stroke patients. It is unknown whether the THRIVE score can also predict outcome in everyday clinical practice. Using our prospectively obtained stroke database the utility of the THRIVE score to predict clinical and radiological outcome in everyday clinical practice was analysed.


Objective To observe the expression of protein inhibitor of activated STAT3(PIAS3) in human gliomas of various pathological grades and to study the relationship between PIAS3 and pathological grades.Methods Immunohistochemical staining was used to detect the expression of PIAS3 in 50 gliomas of various pathological grades and 5 normal brain tissues.The positive rate and the labeling index were counted and compared.Results No PIAS3 was expressed in normal brain tissues.The positive rate of total samples was 56%(28/50).With the advance of pathological grade,the positive rate and mean labeling index for PIAS3 in gliomas increased accordingly.The significant difference in positive rate was not found among grades Ⅰ,Ⅱand Ⅲ(P0.05),but existed between grades Ⅰ-Ⅲ and grade Ⅳ(P0.01).Labeling index was significantly higher in high grades(Ⅲ,Ⅳ) than in low grades(Ⅰ,Ⅱ)(P0.05),but showed no remarkable difference betweenⅠand Ⅱ,and between Ⅲ and Ⅳ(P0.05).Conclusion PIAS3 is expressed in human gliomas,closely correlated with the pathological grade and malignant intensity.PIAS3 may be involved in the development and progression of gliomas.


The fast development in digital technologies during the digital era confronts individuals with situations that require the utilization of an ever-growing assortment of technical, cognitive, and sociological skills that are necessary in order to perform effectively in digital environments. These skills have been termed in recent literature 'digital literacy' (Gilster, 1997). Digital literacy is more than just the technical ability to operate digital devices properly; it comprises a variety of skills that are utilized in executing tasks in digital environments, such as surfing the web, deciphering user interfaces, operating video games, searching in databases, and chatting in chat rooms. In the modern era, digital literacy has become a "survival skill": a key that helps users to work intuitively in executing complex digital tasks. In recent years, extensive efforts are made to describe and conceptualize the cognitive skills that users employ in digital environments (e.g. Burnett & McKinley, 1998; Zins, 2000; Cothey, 2002; Hargittai, 2002; Marsh, 2005). Unfortunately, these efforts are usualy local, focusing on a selected and limited variety of skills, mainly information-seeking skills (e.g. Zins, 2000), and, therefore, they do not cover the full scope of the term digital literacy. Eshet-Alkalai (2004) has established a holistic conceptual model for digital literacy, arguing that it covers most of the cognitive skills that users and scholars employ while working in digital environments and, therefore, providing researchers and designers of digital environments with a powerful framework and design guidelines. This framework was derived from the analysis of large volumes of empirical and qualitative information regarding the behavior of users in digital environments and was studied empirically by Eshet-Alkalai & Amichai-Hamburger (204), who tested the performance of different groups of computer users with tasks that require the utilization of different digital skills. The publication of Eshet-Alkalai's model of digital thinking skills has led to an extensive debate within the community of instructional technology designers, researchers and educators, as to its validity and completeness,. This debate (Aviram & Eshet-Alkalai, 2006) confirmed the validity and value of the model, but indicated that it lacked a sixth thinking skill: the Real-time thinking skill, which relates to the ability of users to perform effectively in advanced digital environments, mainly high-tech machines, multimedia games and multimedia training environments, that require the user to process simultaneously large volumes of stimuli which appear in real-time and at high-speed.


In this paper we present the concept of adaptive expertise and relate this concept to the design curriculum offered by the Institute for Design Engineering and Applications (IDEA) at Northwestern University. The model of adaptive expertise suggests that instruction and assessment include a balance of "efficiency" and "innovation". These two dimensions are first described from a theoretical perspective, then are discussed in more concrete terms in the context of the design experiences provided in IDEA. The model of adaptive expertise suggests that by providing learning experiences that balance these two dimensions we better prepare students to flexibly apply their knowledge in innovative ways. Since these aims are so closely aligned with the goals of design, we offer adaptive expertise as the target for engineering design education.Copyright © 2006 by ASME


In this paper we consider the problems of realizing an optical associative memory for use in new generation supercomputers. The problem of creating a fast high-capacity associative memory is solved by combining several associative memory modules into the whole system.


The article reviews the international new allocation in the band 1 300~1 350MHz to Radio Navigation-Satellite Service(RNSS)at WRC-2000,and analyzes the limitation and potential risk in utilization of this band by Radio Navigation-Satellite Service uplink signal.


The banking sector has undergone a complex but comprehensive structural change since 1991. The main intention of the banking sector reforms was to encourage a diversified, efficient and competitive financial system with the ultimate objective of improving the allocative efficiency of resources through operational flexibility, improved financial viability and institutional strengthening. Two decades passed since then, hence it is important to analyse and compare the performance of private and public sector banks functioning in India. For these purpose variables like Deposits, Advances, Investments, Interest Income, Interest Expenses, Number of banks, Number of Employees, Business per Employee and Profit per Employee are considered for a period of five years from 2007–08 to 2011–12. Descriptive statistics and correlation is used to measure the movement of variables and to analyse the relationship among the variables. The analysis shows that deposits, advances and investments are more in Public Sector Banks than in Private Sector Banks. However, Business per Employee and Profit per employee is more in Private Sector Banks than in Public Sector Banks.


this way Those who have tried to rear orphaned suckling animals on the milk of another species may have felt sad and frustrated when they failed. But they may see the situation in a different light if they look at it this way. The milk of each species is adapted in quality and quantity to meet the nutritional requirements of the young of that species, from the time of birth until weaning. The young may be large or small, and grow rapidly or slowly, yet each milk provides sufficient of all nutrients without any excess that the immature kidneys cannot excrete. Moreover, the digestive system of each species can deal with the constituents of the milk in the quantities delivered to it at anyone time. The great diversity in composition of mammalian milks is necessary because of the wide variation in the requirements of suckling animals. After the mammal is born it moves from the aqueous environment of the uterus where all its requirements had been met by the matemal-placentalfoetal blood circulation to an environment of air, and its first requirement is for oxygen. So its circulation is re-routed, its lungs expanded and the newborn begins to breathe. Its next requirement is for food to provide energy to maintain the body temperature in an environment often colder than the uterus. Some species have a 'store' of energy in the body when they are born; the human infant has a layer of subcutaneous white fat, and the rabbit and guinea pig have large pads of brown adipose tissue round the blood vessels at the back of the thorax. In other species some brown adipose tissue is diffusely distributed round the blood vessels of the neck. Local release of nor-adrenalin in response to a fall in body temperature hydrolyses triglycerides in the brown fat cells, which is followed by intracellular oxidation of fatty acids. This produces heat, and the proximity to blood vessels enables heat to be transported round the body, which helps to maintain body temperature. The other 'energy store' at birth is glycogen. The pig has exceptionally large amounts of glycogen in its liver and skeletal muscles at birth, and many species have small amounts in the liver and heart. None of these energy sources provides the newborn mammal with energy and heat for very long, and all newborn must soon find their way to one of the mother's mammary glands, the insignia of the mammal. In some species, the cat for example, the mother licks her mammary glands thoroughly before the young are delivered; in others, the cow for instance, the mother licks her newborn calf; in yet others including the pig, the mother makes no attempt to interact with her young as they are born, and they must find their own way round her large body to reach the source of food. The young of immature 'altricial' species are born blind and deaf, but they also find their own way to the mammary glands, which the mother makes accessible to them. Smell and taste are the first senses to develop, and it is thought that these young may be directed by a pheromone secreted by the mother's mammary gland or in her saliva, though warmth is undoubtedly important. All newborn mammals have a strong sucking reflex; sucking involves considerable activity of the jaw muscles which must be more highly developed than other muscles in immature altricial species. The number of nipples or teats varies among species, but there are usually more nipples than the number of young born. Species having large litters have mammary glands in two rows along the mother's body; the pig has 14 glands, rat 12, dog 10, and cat eight; the mother lies on her side to suckle. Most precocial species have one or two young; they have inguinal mammary glands with two or four teats, and mother and young stand to suckle. Primates have two pectoral mammary glands and the mother sits or lies to suckle, supporting her infant with her arms or forelimbs. The elephant also has pectoral glands, and mother and young stand to suckle, the single young swinging its trunk to one side so that its mouth can suck the teat. Some marine mammals, seals for example, haul out of the sea on to land or ice to deliver and suckle their single young. Others, whales and dolphins, deliver and suckle their single young in the sea. The whale swims near the surface for delivery of her calf and as soon as it is born she makes a


Professors were the academic elite during the period of Republic of China. They were living in colleges and universities, engaging in production, creation and dissemination of knowledge, formed a relatively independent academic community, and cultivated and promoted the growth of academic community in order to rebuild the community center. In this process they accumulated a certain amount of political resources, and established the link between knowledge and power. It was the foundation for political participation through which they realized the leap from academic research to politics.


Background : The ASA IPPA Central Java has been conducting a series of IEC activities of HIV prevention programmes for young people regularly. These activities are conducted by ASA volunteers by providing a lecture to middle and high school students. Unfortunately, these activities have never been evaluated in terms of the methods, the materials and the outputs of the lecture. This study observes the IEC process of HIV prevention for young people conducted by ASA volunteers. Method : An observation technique using check lists has been used to observe the process of the IEC activities which were conducted by the ASA volunteers. The performance of the communicators, the curriculum provided, the responses of the target group and the media used, were observed directly during the IEC activities. Focus group discussions with students and indepth interviews with coordinators of IEC activities in each school, were also conducted to obtain more detail information. Two middle schools and three high schools which selected purposively have been participated in this study. Results : The study shows that the performance of the communicators during the IEC activities were relatively good, particularly in terms of language, skills of communication technique and relationship with the audiences. Although not all questions asked by the audiences, have been answered by the communicators, particularly unrelated topics to HIV/AIDS and drugs, using new terminology during a lecture has made many students interested to listen and provided some good responses. In terms of the IEC materials, the middle schools were more focused on drugs, whereas the high schools were more concerned in HIV/AIDS prevention. Each lecture provides an additional programmes such as HIV/AIDS film and drug user cases in VCD format. This study suggests that the skills of communicators and the materials of the IEC, should be improved regularly in order to increase the fit between the IEC activities and the audience needs. The usage of audio visual aids during the IEC process should be optimized to make it easier for the audiences to understand the materials being provided. The output assessments should also be conducted in order to obtain direct feed back from the audiences. Keywords : IEC process, HIV/AIDS, Students.


The paper first looks back the design of urban street space and then analyzes the background of meaning of the City Eco street. Based upon the studies above, this paper proposes some design criteria of building modern city Eco street.


The main products of carbon fixation in the red algae are sulfated cell‐wall polysaccharides, floridean starch, and low molecular weight (LMW) carbohydrates, mainly floridoside. In the red microalga Porphyridium sp., sulfated polysaccharide—cell bound and soluble—comprises up to 70% of the algal biomass. The purpose of this study was to elucidate the partitioning of fixed carbon in Porphyridium sp. toward the different products of carbon fixation. Using pulse‐chase technique with [14C]bicarbonate, we followed 14C flow into the major compounds, namely, cell‐wall polysaccharide, floridoside, starch, and protein, under various environmental conditions (i.e. carbon dioxide enrichment and nitrate starvation). 13C‐NMR and gas chromatography analysis showed the main LMW product in Porphyridium sp. to be floridoside. After the short [14C]bicarbonate pulse (20 min), 42%–53% of total 14C uptake was initially found in floridoside. The appearance of 14C in the soluble polysaccharide was evident immediately at the end of the 20‐min [14C]bicarbonate pulse. The specific radioactivity in the floridoside fraction declined by 80% after the 48‐h chase, this decline being accompanied by increased labeling of starch and the soluble polysaccharide. In cells exposed to high CO2 concentration, larger amounts of 14C (about twice as much) were channeled into starch and soluble polysaccharide than in cells under low CO2 concentration. The most significant increase (1500%) in labeling during chase was found in the soluble polysaccharide of the nitrate‐deprived cultures. It therefore seems likely that the large amounts of carbon incorporated by Porphyridium sp. cells into floridoside were subsequently used for the synthesis of macromolecular components. The data thus support the premise that floridoside serves as a dynamic carbon pool, which channels the fixed carbon toward polysaccharides and other end products according to the ambient conditions.


Objective:To investigate the prevalence of overweight and obesity,hypertension,hyperlipemia,hyperglycemia,fatty liver on resident of Yueqing,to get the scientific data for preventing illness and making a diagnosis to the people of community.Methods:To statistic and analysis the health checking data of resident who are in the district in 2009 were collected and analyzed.Results:The prevalence of overweight,obesity,hypertension,hyperlipemia,hyperglycemia and fatty liver are 28.46%,5.44%,24.37%,43.94%,9.47% and 32.70% respectively in 9438 samples,the prevalence of men and women were significant different(P0.001).The prevalence increase as the age increase(P0.001).Conclusion: The prevalence of obesity,hypertension,hyperlipemia,hyperglycemia and fatty liver of resident of Yueqing exist different in sex and age,we should prevent and health care the diseases according to sex and age for the people.


Hand foot and mouth disease is an acute viral illness caused by the Coxsackie virus. The contagious nature of the disease is threatening as the disease primarily affects the children of school going age. As the name suggests, typical lesions will be seen over the hands, feet and in the oral cavity. The child gets irritated, febrile and lethargic. Oral lesions can add up to the general weakness as the child becomes reluctant to food. Diagnosis can be made based on the clinical features alone. As the disease outbreaks were reported from neighbouring countries like China and other South Eastern countries, awareness amongst the dentists, general physicians and dermatologists usually can play a role in reducing the suffering of the patient. This case report describes about a 3 year old male child presenting with typical ulcerative lesions over the hands, feet and oral mucosa.


An efficient catalytic method to convert an alpha-C-H bond of N-alkylamines into an alpha-C-alkynyl bond was developed. In the past, such transformations were carried out under oxidative conditions, and the enantioselective variants were confined to tetrahydroisoquinoline derivatives. Here, we disclose a method for union of N-alkylamines and trimethylsilyl alkynes, without the presence of an external oxidant, and promoted through cooperative actions of two Lewis acids, B(C6F5)3 and a Cu-based complex. A variety of propargylamines can be synthesized in high diastereo- and enantioselectivity. The utility of the approach is demonstrated by late-stage site-selective modification of bioactive amines. Kinetic investigations that shed light on various mechanistic nuances of the catalytic process are presented.