2.5D structures have received attention because of their excellent interlaminar mechanical properties. However, there is a lack of research on impact progressive damage, damage mechanisms and internal damage morphology. This paper investigated the low-velocity impact behavior and damage mechanisms of 2.5D woven carbon/epoxy composites through a couple of numerical-experimental approach. Two different impact energy levels, 15 J/mm and 20 J/mm, were designed for all the samples using drop weight impact equipment. Then Micro-CT was employed to identify the impact damage volumes and damage distribution of 2.5D woven composites. A novel whole-local finite element model was proposed based on the tests results and Micro-CT images. The experimental results indicated that the impact energy has a significant effect on the damage modes of 2.5D woven composite. Moreover, the numerically predicted mechanical curves and damage modes exhibit good consistency with the experimental results. Importantly, the numerical simulation results showed that the damage mode of 2.5D woven composites under impact energies of 15 J/mm was mainly controlled by yarn-matrix debonding. With the increase of impact energy per unit thickness, the dominated failure mode of 2.5D woven carbon/epoxy composites changes from yarn-matrix debonding to delamination and eventually to yarn breakage.


The article is devoted to an analysis of health-impaired children social integration. The author identifies six major stages in the development of a society's attitude towards disability as a problem and disables children as a distinct social group: from absolute rejection and even destruction of health-impaired persons to public recognition of equal rights irrespective of health conditions. In the article, the author compares Russian and European experience in health-impaired-people-targeted aid-provision and concludes that Russian experience is significantly different from that of Europe, where aid programmes were informed by the goals and aims of the state. By mid-20th century, European society had come to a realization of health-impaired people's social equality and begun to develop a social model of disability, the underlying premise of which was active social assistance provided for persons with special needs in the course of their socialization. The predominant attitude in Russia was characterized by plaintive compassion and pity, which shaped the support/aid model as initially grounded in private charity and, later, state provision. By the end of the 20th century, due to global socio-economic reforms, a social model of disability came to be created in Russia. However, legal deficiencies, fund and qualified personnel shortages, as well as the negative stereotypes have so far been challenging the development of the model. As a conclusion, the author insists that the adaptivity model currently in effect be replaced by a self-actualization model. The author provides practical recommendations concerning personnel training and re-training in the field of social follow-up of healthimpaired people.


The ground-(S0) and excited -(S1 and T1) state spectra of seven derivatives o f 9-acetoxy- 10(4´-acetoxy)phenylanthracene were determined in the region 50000 - 15000 cm -1 (200 - 660 nm). Comparison of these spectra to the unsubstituted molecule (anthracene) indicates the presence o f bathochromic shift and the steric effect. The substituents cause changes of positions of the energy levels (bigger shifts are noticed for low lying states) and also changes of the absorption intensities of some transitions. The steric hindrances between the phenyl-substituents and the anthracene skeleton are more pronounced if the - OAc(- Me) group or a heavy atom is introduced at position 2´o f the phenyl ring. Molecules possessing such substituents at the meso-position exhibit spectroscopic properties characteristic for a plane molecule in the S0 and S1 states; they show a better preservation of the mirror symmetry between the absorption and fluorescence spectra, lower Stokes shifts and the destabilization energies and bigger fluorescence quantum yields.


Findings: We found that the most significant factor in the willingness to run a business is the ability to accept risk. Other factors, such as the country of origin or respondents' gender, are also statistically significant. Prior work experience did not prove to be a strong predictor. Implications & Recommendations: The results show that the willingness to run a business, which forms an integral part of EI, is to a large extent influenced by relatively stable variables (i.e., personal characteristics, gender, and country of origin). Therefore, it is possible that certain measures aimed at starting and developing a business (e.g., education) will be less effective if the monitored variables (e.g., personal characteristics) are not taken into account. Contribution & Value Added: The added value of this study is the identification and verification of variables influencing business within the international context. Article type: research article


Of particular importance is the profile migration of pollutants, which is most intense flows in spring, autumn and summer with the loss of a large amount of rainfall, when there are intense downdrafts soil moisture. The migration of heavy metals limit their deposition processes on geochemical barriers. The study of the profile of migration and accumulation of heavy metals showed that the metals have varying behavior of soils, there is a change in the profile of their contents. The article deals with the dynamics of the distribution of mobile forms of heavy metals in different soils of the Orenburg region, the results of determination of pH in these soils. A method for evaluating the intensity of migration of heavy metals in the profile of chernozem and dark chestnut soils built using regression equations and values of, which is a constant and depends on the type of soil and the chemical element. It was revealed that the profile of the southern black earth is an increase in the concentration of heavy metals such as lead, nickel, chromium, copper, cadmium, cobalt, zinc and manganese. For chernozem incompletely rubbly decrease the concentration profile of elements such as lead, nickel, copper and cobalt. Dark brown soil: is an increase in the concentration of lead in the soil profile and the reduction of zinc in the profile. For a typical black soil on the profile decreases the concentration of zinc. For ordinary chernozem a decrease in the concentration of manganese in the soil profile.


When we take a job with a company, we instantly develop a large network of new acquaintances. The relationships we have with co-workers are called "nonvoluntary relationships" because as long as we hold a job with that organization, we have no choice but to interact with the other people who work there. As long as we like our co-workers, the nonvoluntary nature of these relationships is unremarkable, but for most of us it is inevitable that we won't like a few of those people. This can cause a difficult situation. Relationships with co-workers we don't like are stressful. The stronger our disdain and the more closely we have to work with such individuals, the more stress these relationships cause. This article covers: * How to cope * What research tells us * Tips for dealing with people we don't like * The importance of mastering this skill Disciplines Communication | Interpersonal and Small Group Communication | Organizational Communication | Other Communication | Speech and Rhetorical Studies Comments Copyright © 2000, Jonathan Hess; all content used from this article must be attributed properly. This article is available at eCommons: http://ecommons.udayton.edu/cmm_fac_pub/8


Objective: To compare the long-term outcomes of CT (conservative treatment) and early RC (radical cystectomy) for T1G3 bladder cancer. Methods: A computer-based online search was performed by using EMBASE, Cochrane Library, PubMed, CNKI (China National Knowledge Infrastructure), Wanfang and Sinomed databases. Studies of CT vs early RC for T1G3 bladder cancer in accordance with the inclusion and exclusion criteria were included. CT indicated TURBT (transurethral resection of bladder tumor) followed by bladder instillation. Quality of the studies was assessed using Newcastle-ottawa scale. Data were extracted from the studies by 2 independent reviewers. The Meta-analysis was performed by Stata 11.0 software. Results: A total of 8 case-control studues involving 1 018 patients were included. The baseline of these studies was consistent, as the analysis showed no statistical significant differences in age, gender and the proportion of multiple lesions. Meanwhile, there were no statistically significant differences in five-year survival rate [OR (odds ratio): 1.290, 95% CI (confidence interval): 0.898-1.852, P = 0.168], tumor-specific mortality (OR: 0.797, 95% CI: 0.587-1.080, P = 0.143), and rate of tumor progression (OR: 1.278, 95% CI: 0.865-1.887, P = 0.219]. But the ten-year survival rate of CT group was higher than that of the RC group (OR: 1.794, 95% CI: 1.214-2.650, P = 0.003) with a publication bias. Conclusion: For T1G3 bladder cancer, the five-year survival rate, tumor-specific mortality and rate of tumor progression of CT group and RC group had no significant differences. In consideration of greatly declined quality of life, early conservative treatment may be appropriate for the patients with T1G3 bladder cancer. However, such clinical trials are almost retrospective, so large prospective clinical randomized controlled trials are needed for further assessment. DOI:10.3781/j.issn.1000-7431.2013.10.010


Sexually selected traits are often driven to costly extremes by persistent directional selection. Energy acquisition and allocation can therefore influence variation in traits subject to both precopulatory and postcopulatory sexual selection, though the later have received much less attention. We tested the condition dependence of sperm morphology, sperm count, and fertilization success in a promiscuous lizard (Anolis sagrei) by 1) collecting sperm samples from wild males that varied naturally in body condition, 2) experimentally altering the body condition of captive males through dietary restriction, and 3) analyzing genetic paternity data from competitive mating trials between captive males that differed in body condition. In both wild and captive males, the length of the sperm midpiece decreased with body condition. Experimental food restriction decreased sperm production, decreased length of the sperm head, increased length of the sperm midpiece, and increased variance in sperm morphology within individuals. When restricted to a single copulation, males on high-intake diets exhibited a slight but nonsignificant fertilization advantage. Reanalysis of a previous experiment in which high- and low-condition males were sequentially allowed to copulate ad libitum for 1 week revealed a significant fertilization bias in favor of high-condition males. When controlling for mean treatment effects on the proportion of offspring sired and on sperm phenotypes, multiple regression revealed negative correlations between fertilization success and sperm head length, midpiece length, and sperm count. Collectively, our results suggest that condition-dependent fertilization success in A. sagrei may be partially mediated by underlying condition dependence of sperm morphology and sperm count.


The transition of Russia to a digital society actualizes the issues of the formation of universal competencies that are in demand in the professions of the future. The article presents the content of supra-professional competencies that allow performing professional tasks at a high level in the context of the digital transformation of the economy. For the formation of meta-competencies, it is necessary to use the resources of the digital educational environment, online tools that provide not only high-quality access to modern knowledge, but change the ways of thinking, which form the ability to interact with a society through the use of information and communication technologies.


Postoperative complications represent a basic quality indicator of outcomes, but are not systematically measured. This situation has negative consequences that are ignored. An accurate assessment could help to evaluate the real morbidity, establish measures for improvement, increase efficiency and identify benchmark services. I present a personal review of the situation.


The effect of high pressure (0\char21{}8 GPa) on the magnetic structure of polycrystalline samples of ${\text{La}}_{0.5}{\text{Ca}}_{0.5\ensuremath{-}x}{\text{Sr}}_{x}{\text{MnO}}_{3}$ $(0.1\ensuremath{\le}x\ensuremath{\le}0.4)$ manganites at 5 K is investigated using neutron-diffraction technique. Application of pressure is found to modify the previously reported magnetic structure, observed under ambient conditions, in these compounds [I. Dhiman et al., Phys. Rev. B 77, 094440 (2008)]. In $x=0.1$ composition, at 4.6(2) GPa and beyond, $A$-type antiferromagnetic structure is found to coexist with charge-exchange (CE)-type antiferromagnetic phase, observed at ambient pressure, with ${T}_{\text{N}}\ensuremath{\sim}150\text{ }\text{K}$. For $x=0.3$ sample, as a function of pressure the CE-type phase is fully suppressed at 2.3(1) GPa and $A$-type antiferromagnetic phase is favored. Further Sr doping at $x=0.4$, the $A$-type antiferromagnetic phase is observed at ambient pressure and for $Tl{T}_{\text{N}}$ $(\ensuremath{\sim}250\text{ }\text{K})$. This phase is retained in the studied pressure range. However, the magnetic moment progressively reduces with increasing pressure, indicating the suppression of $A$-type antiferromagnetic phase. The present study brings out the fragile nature of the CE-type antiferromagnetic state in half-doped manganites as a function of pressure and disorder ${\ensuremath{\sigma}}^{2}$. We observe that pressure required for destabilizing the CE-type antiferromagnetic state is reduced with increasing disorder ${\ensuremath{\sigma}}^{2}$. External pressure and changing $A$-site ionic radii have analogous effect on the magnetic structure.


Eu doped YBa2-xEuxCu3O7-δ superconductors with x 0. 5 were synthesized and studied. The microstructure of YBa2-xEuxCu3O7-δ superconductors was characterized by X- ray diffraction with Rietveld refinements. Eu may occupy Y- site,Ba - sites and Cu - site, which depends on its content.The orthorhombic strain vary with the content of Eu, which may affect the electronic transportation. We found that Eu3+ /Eu2+ ions prefer to replace Ba at Ba sites,which gives little influence on superconductivity. The spin gap temperature,Ts, in the normal state decreases with increasing the Eu contetn.


ABSTRACT Virtual environments as spaces for leisure are rapidly emerging within the zeitgeist of 21st century leisure practices. One such environment is the Zwift cycling and running app which provides a series of virtual worlds where cyclists and runners can train, race, and socialise with a global community from their own home. As four authors, we are all in some way curious or engaged with Zwift as a platform for our own leisure. We therefore developed a 'community of inquiry' to provide an initial foray into Zwift as a virtual leisure space. We each produced a section of the paper which focused respectively on assemblage theory, micro-sociology, gender, and morality. Through critique and the spirit of collegiality, these texts were refined and are presented in the paper as separate yet interlinked narratives. Our community of inquiry then reconvened to consider the mechanics of game design and to present Zwift as exhibiting the components of an interreality. The paper concludes with implications for further research which includes considering Zwift as a third space and as a panopticon.


From the Publisher:
C# can be ported to multiple platforms and used to develop any type of program, from a Windows service to a Web component. This book focuses on the core C# language. It covers the language syntax, provides samples, and shows you how to use C# with ASP.NET, WinForms, and Web Services. The book illustrates C# syntax and design strategies and how C# integrates with other languages—a real-world consideration. It also uses examples tied to Visual Studio.NET. It provides examples of common coding techniques and information on the CLR assemblies and classes that can be leveraged in your everyday tasks.


To determine the effect of the quality of sand on the properties of the foam is necessary to consider its properties is the ratio of grains of different factions, called the module size Mach, pollution alloy ultrafine particles dust, mud or clay, the absence of organic impurities and particularly humic acids, harmful impurities sulfur and sulfuric compounds, mica, amorphous silica modification. Based on this it is necessary to find such areas of sand mining on the territory of Primorsky Krai, to improve the quality of foam.


This article looks at the issue of the validity of reservations to international human rights treaties through the lens of the International Court of Justice (ICJ or Court). A broader perspective is created by comparing the respective positions adopted by other international bodies, such as the European Court of Human Rights (ECtHR), the Human Rights Committee (HRC), and the International Law Commission (ILC or Commission). In its 1951 advisory opinion in the Reservations to the Genocide Convention the Court provided a general legal framework on the issue of the validity of reservations to multilateral treaties. A proper understanding of that opinion and the subsequent practice of the human rights courts and quasi-judicial bodies has been essential with regard to informing and guiding the Commission in its work on this topic and during the preparation of its forthcoming 'Guide to Practice'.


INTRODUCTION Small changes in knee joint mechanics are hypothesized to be a contributing factor in the initiation and progression of osteoarthritis. Our lab will analyse parameters of joint contact mechanics based on the relative position and separation of articulating surfaces (e.g., proximity distance). This summer research project aimed to optimize an existing Thin Plate Spline (TPS) mathematical surface modeling routine [1] for human bone surfaces. These modifications were necessary to accommodate differences in surface digitization methods, scan resolution, desired surface model grid resolution, and to model the highly curved femoral surface. There were three main research objectives: (1) determine the number of sample points needed to ensure a dense and continuous grid without holes, (2) determine a method to model curvatures greater than 75 o , and (3) determine the degree of surface smoothing. METHODS To answer the first question, the number of surface points (SP) and grid cutting distance (CD) were systematically increased from 5000-9000 and 1.5-2.0, respectively. Fast computation times and a continuous spline grid (i.e., no holes) were the criteria used to determine appropriate SP and CD optimisation parameters. Two approaches that sectioned the femoral surface into 3 components were evaluated. Sectioning the femur was done in an effort to circumvent the curvature errors that occurred when modeling the femoral surface (Figure 1.a.). Each method rotated the anterior and posterior data tangentially to the xy-plane, which reduces spline fitting errors. The most important criteria for selecting the final approach was to keep the seams of the three femoral TPS sections away from the main distal contact area. Lastly, the amount of tibial smoothing was evaluated over a range smoothing factors (λ=0.2-2.2), and the resulting surfaces compared to completely interpolated and noisy (1mm random noise) surfaces . RESULTS Acceptable grid continuity and computation time (~1.7mins) were found at 5000 SP and 1.5mm CD for the tibial surface. Both 5000 SP with 1.8mmCD and 7000 SP with 2.0mm CD gave a continuous femoral spline grid, but resulted in longer computation times. At 9000SP, the spline grid was always continuous at the cost of greater computation time (10 minutes+ at all CD values), but curvature errors remained. Sectioning the femoral surface (anterior, posterior and distal) eliminated these curvature errors (Figure 1.b). However when tibiofemoral proximity was calculated, significant errors occurred at the two seams of the surfaces. Figure 1. Sample size of 5000pts and 2.0mm CD a) Original TPS fit b) TPS fit with 3 surface sections. Based on the sensitivity analysis of λ values, λ=0.3 was chosen to test whether this resulted in a sufficient amount of tibial surface smoothing. The chosen smoothing was very close to the interpolated surface, but did not smooth out the added noise sufficiently. DISCUSSION AND CONCLUSION Appropriate SP and CD values were determined for tibiofemoral surfaces, and by sectioning the femoral surface into 3 components reduced spline fit artefact at the highly curved anterior and posterior femoral regions. A sectioned femoral surface improved the TPS geometric fit, but errors persisted when tibiofemoral proximity was mapped. The section methods developed here therefore require further refinement for proximity distance mapping. Lastly, more smoothing is likely required for tibial surfaces. This work is an important first step towards optimizing tibiofemoral surface modeling used in joint contact mechanics. REFERENCES 1. Boyd, SK, et al. J Biomech Eng 121 : 525-532, 1999.


One hundred twelve species (including 23 new species and 5 unrecorded species) of the genera Calliphora, Tainanina, Onesia, Polleniopsis, Melinda, Hemipyrellia, Lucilia, Phumosia, Euphumosia, Dexopollenia, Bengalia, Chrysomya, Rhinia, Chlororhinia, Stomorhina, Idiella, Metallea, Platytropesa, Stilbomyella and Paramenia are recognized from New Guinea, Bismarck Archipelago and Bougainville Island as a result of field works supported by Grants-in-Aid for Overseas Scientific Survey from the Japan Ministry of Education, Science and Culture since 1973. This paper, as the first one of my report, deals with Calliphora, Tainanina, Polleniopsis and Melinda and presents a key to all the 20 genera mentioned above. Three new species, Calliphora (Paracalliphora) kanoi, Melinda ruficornis and Melinda jlavipennis are described.


Acute myeloid leukemia (AML) is a high-risk malignancy with overall poor outcomes across the age spectrum. Attempts to intensify cytotoxic chemotherapeutic regimens in recent decades have been limited by toxic acute and late effects, establishing the necessity of targeted therapy development. Immunotherapy is a highly promising treatment strategy in AML; however, its development has been limited as agents with potent anti-leukemic activity often confer significant hematopoietic toxicities. We previously reported the identification of an ideal potential immunotherapeutic target, mesothelin (MSLN), a cell surface protein expressed in 37% of childhood and young adult AML as well as older adult AML that, importantly, is absent in normal hematopoietic cells. Mesothelin is overexpressed in a number of solid tumors and has been studied as a target in solid tumors with various immunotherapeutic agents, including the antibody-drug conjugate (ADC) anetumab ravtansine (AR), comprised of an anti-MSLN antibody conjugated to the maytansinoid tubulin inhibitor DM4. We evaluated AR as well as a novel MSLN-targeted ADC for their ability to induce MSLN-directed cytotoxicity in several cell lines engineered to express MSLN.
 As we have previously reported, the leukemia cell line K562 transduced to overexpress MSLN (K562+MSLN) was highly sensitive to AR in vitro with an IC50 of 1.4 nM (Fig. 1a). Furthermore, AR was highly active in vivo in K562+MSLN xenograft-bearing mice. We sought to extend the study of AR's cytotoxicity in AML, to illustrate its potential as a therapeutic agent, in 3 additional AML cell lines, MV4;11, Kasumi-1, and Me-1, lentivirally-transduced to express MSLN, with cell-surface MSLN levels confirmed by flow cytometry. In vitro cytotoxicity assays demonstrated potent MSLN-dependent cytotoxicity of AR in MV4;11+MSLN cells with IC50 0.009 nM, compared to 1.9-3.8 nM in control experiments with parental cells or isotype control (IC) treatment (Fig. 1b). AR had limited MSLN-dependent activity in Kasumi-1+MSLN, with an IC50 of 28 nM, compared to 76-87 nM in controls (Fig. 1c) and no MSLN-dependent cytotoxicity in Me-1+MSLN, compared to controls (Fig. 1d). Previous reports suggest that DM4 is a substrate of the drug resistance protein P-glycoprotein (ABCB1). We evaluated drug resistance protein expression, including ABCB1, MRP1-6, LRP1, and BRCP, using RNASeq in representative AR-sensitive and AR-resistant cell lines, MV4;11 and Kasumi-1, respectively, and examined published RNASeq data for K562 and Me-1, and found that P-glycoprotein expression correlated with resistance to AR, measured by the IC50 (R2 = 0.995, p = 0.002).
 To optimize ADC targeting of MSLN in AML, we created a novel MSLN-targeted ADC using an alternative MSLN antibody with an alternative chemotherapeutic payload, pyrrolobenzodiazepine (PBD) dimer, and molecular linker (anti-MSLN-PBD) as well as 3 control compounds: an anti-MSLN ADC with a DM4 payload (anti-MSLN-DM4) and isotype controls comprised of anti-Tetanus toxin antibody conjugated to PBD (IC-PBD) or DM4 (IC-DM4). In vitro cytotoxicity assays in the 4 aforementioned MSLN+ leukemia cell lines revealed potent MSLN-dependent cell kill with the novel anti-MSLN-PBD compared to controls in all but Me-1+MSLN, with IC50 of 1.6 pM-8.3 nM (Fig. 1e-h). Notably, unlike AR, anti-MSLN-PBD was able to confer MSLN-dependent cytotoxicity in Kasumi-1+MSLN. Sensitivity to anti-MSLN-PBD was independent of P-glycoprotein expression.
 Mesothelin is a cell-surface protein previously recognized as an attractive immunotherapeutic target in solid tumors that is aberrantly expressed in a sizeable subset of AML patients of all ages, and herein we report successful targeting of MSLN in leukemia cells in vitro with antibody-drug conjugates. AR, an ADC well-tolerated in phase I testing for solid tumors, showed dramatic MSLN-dependent cytotoxicity in 2 cell lines at clinically-achievable doses. To optimize MSLN targeting in AML, we created a novel MSLN-targeted ADC with a PBD dimer payload, which conferred a high degree of MSLN-dependent cytotoxicity in vitro in 3 of 4 MSLN+ leukemia cell lines tested. Mesothelin-directed ADCs hold great promise for the treatment of MSLN+ AML across the age spectrum and warrant additional pre-clinical and clinical evaluation as potential novel immunotherapeutics for AML.

 No relevant conflicts of interest to declare.


Referral management centres have been set up in an attempt to control the flow of patients from generalist to specialist services.1 Those proposing and creating such centres seem to view a referral as a simple administrative transaction, whereas those working in primary care know that a successful referral is a much more complex and challenging phenomenon.

Referrals cannot be understood simply in terms of demand. Many patients have to be persuaded to accept referrals and this requires painstaking and careful negotiation within which wide-ranging fears are explored and discussed. The referral process must be able to respond not only to expressed demand but also to unexpressed need.

Referrals occur either because the diagnosis …


This thesis examines the causes behind why England and Sweden, as
European Union (EU) Member States that share a higher concern for animal
welfare, suffer similar financial drawbacks and a decrease of their farmers'
competitive strength, in spite of their fundamentally different regulatory
approaches to transposing EU law. This complex situation is investigated by
tracing the issue to its origin: the inherent tension stemming from the dual
classification of the animals in EU primary law as both sentient beings and
tradable goods.
Farm animal welfare is regulated by minimum harmonising EU Directives,
which permit Member States to implement stricter domestic regulatory
standards. This thesis argues that these stricter standards, while being
zoocentrically important in terms of enabling a higher level of farm animal
welfare, also have a substantial negative economic impact upon the affected
farmers, due to the higher input costs. The issue arising is that minimum
Directives effectively negate the competitive strength of the farmers in
'stricter' Member States, as their domestic produce competes directly
against imported products from Member States whose national legislation is
closer to the minimum standard established by the EU Directives.
This thesis critiques this situation as untenable and submits that the farmers'
competitive strength in stricter Member States can be improved by a shift in
consumer purchasing behaviour, achieved by a programme that raises
public awareness. The research outcome is a recommendation of the
introduction of an EU-wide farm animal welfare labelling policy, one that
would allow consumers to distinguish high-welfare products from low-welfare
ones, where the elevated price commanded by the former would offset the
higher costs incurred in their production. The benefits of this solution are that
it facilitates increased competitiveness within the EU's internal market, while
maintaining and promoting higher farm animal welfare standards.


Characteristics of bubble driven wakes were investigated in a simulated GTL process(0.102 m 1.5 m in height) with viscous liquid medium. Effects of gas velocity(0.04 ~ 0.12 m/s) and liquid viscosity(0.001 ~ 0.050 ) on the wake characteristics such as rising velocity, frequency, size and holdup were determined by employing a resistivity probe method. The wake phase formed behind the rising multi-bubbles as well as single bubbles were detected effectively from the conductivity fluctuations measured by the probe. Compressed, filtered and regulated air and aqueous solutions of Carboxy Methyl Cellulose(CMC) were used as a dispersed gas phase and a continuous liquid medium, respectively. It was found that the rising velocity and size of wake phase increased with an increase in gas velocity or liquid viscosity. The holdup and frequency of wake phase increased with increasing gas velocity due to the increase of gas input into the process with increasing gas velocity. However, the values of holdup and frequency of wake phase decreased with increasing liquid viscosity, since the size of bubbles and thus that of wakes increased with increasing liquid viscosity. The ratio of wake holdup to that of gas phase, which was in the range of 0.25 ~ 0.48, increased with an increase in liquid viscosity but decreased with gas velocity. The wake characteristics were well correlated in terms of operating variables within this experimental conditions.


The present invention is iron, which is characterized by the iron (II) content - provide a carbohydrate complex. The present invention is an iron-also use for the treatment of a process for producing a complex carbohydrate and iron deficiency anemia is also provided. Iron-carbohydrate complexes and iron deficiency anemia


In many services, consumers must rely on experts to identify the type of service they need. In such expert services, diagnosis is a crucial step in which the expert identifies the type of problem and also provides the corresponding treatment. The asymmetry of information between the expert and the consumer leads to inefficiencies in the form of over-treatment: The expert may have an incentive to not reveal the true diagnosis to the consumer in order to sell more expensive services. The expert may extract more revenue through the expensive treatment, but providing such a treatment also requires more service capacity and time. Hence, overtreatments impose longer delays and higher waiting costs for consumers. We find that congestion acts as a natural "fraud cost" and mitigates expert cheating and induces honesty, thus increasing social value. Experts with high capacity utilization are less prone to overtreat. To commit to an honest diagnosis, the expert has to charge high prices and limit demand for his services. Thus, low prices may serve as a signal for overtreatment.


Unlike what is asserted by some authors, the relationship existing amongst spaces travelled at equal and successive times by uniformly accelerated bodies departing from the rest, a relationship which is known as «law of odd numbers», was not contrasted by Galileo through his experiments with inclined planes: this relationship rather emerged through those experiments. The quadratic dependence of the travelled spaces with respect to time is quickly derived from this functional relationship, a fact Galileo was surely capable to prove in a mathematical way despite of no written evidence seems to be known up to date. At the end, Galileo succeeded in connecting his theory of freely falling bodies with certain traditional elements like the Merton rule. It was this version of the theory what was immortalized in his Discourses on Two New Sciences.


Abstract. The goal of the study is to test the hypothesis on the practicality of using the Cobb-Douglas function in the information support of state planning as a method of numerical analysis at the regional management of government. The first part of the article explains the rationale for the development of digital models in public administration, the results of the analysis of modern publications on the study of factors of growth and constraint of economic development and the methods used for these studies. The second part of the article contains the goal and tasks of the study, the basic hypothesis of the study. The third part of the article presents the results of the research carried out on the influ-ence of the main factors of production, labour and capital on the volume of turnover of enterprises using the Cobb-Douglas production function on the example of five branches of economy of Volgograd oblast. The last part of the article summarizes the results of the study. In particular, it is noted that the growth of the turnover of enterprises in the region was positively influenced by both the increase in the value of fixed production assets and wage growth. However, the pattern of declining average efficiency of fixed production assets in all sectors and the fact that turnover rates are higher than the value of fixed production assets may indicate inefficiencies in their use. In two sectors of the region, the extractive industry and construction, there is a decrease in the average effi-ciency of wages, which may indicate ineffective management material incentives to work in the sectors. Based on the results of the research conducted it is concluded that it is appropriate to use the Cobb-Douglas function as a numerical method of analysis in in-forming state planning, including in the management of state programmes at the regional management level to validate the methods and instruments of economic regulation.


SOME degree of cerumen (ear wax) production is normal. However, increased production orcompromised clearance of cerumen can necessitate its removal. While this is mainly a problemin dogs, some cats may also require ear cleaning. This article describes the technique for cleaningears in small animals. It also discusses the principal components of topical ear cleaners that maybe used to clean the external ear canal and highlights those that are safe to use within a long‐termotic care programme (ie, for home treatment over an extended period).


The 1997/98 financial crisis of Thailand has been extensively analyzed and yet, important questions remain to be answered regarding consumer behavior and its implications in regard to the crisis. This paper attempts to analyze the movements of consumer spending in Thailand during the period from 1975 to 1998, in order to shed some light on the causes of the 1997/98 financial crisis of Thailand. A hypothesis of the pro-cyclicality of consumer spending is developed by modifying Mankiw's liquidity constrained hypothesis; it is then tested by using data from various issues of International Financial Statistics and the Bank of Thailand's homepage. Results indicate that consumer spending in Thailand was pro-cyclical during the period from 1990 to 1998 and that this factor partly contributed to the boom-bust of Thailand's economy. The findings of this study suggest that taxation or credit restrictions targeted at luxury consumption may need to be taken in foreign credit-induced booms.1


During installation of GIS at North Beijing 500 kV Substation the constructors overcame many difficulties including short construction schedule,heavy works,high requirements for installation accuracy and strict requirements for environments,etc.They did well the technical preparation,acceptance of equipment,control on the offset of foundation,observation on the foundation settlement and strict control on the environment at the installation site.They also took many measures for quality control.So during the whole AC voltage-withstand test there was no phenomena of breakdown discharge,which has proved the success of quality control for installation of GIS at the substation.


ARVI and flu epidemics occur annually and affect up to 15% of the world population. One of the most common diseases associated with acute respiratory infection is acute rhinosinusitis. According to various epidemiological studies conducted over the past 5 years in more than 30 countries, the incidence of rhinosinusitis has doubled, and transition from acute to chronic rhinosinusitis is observed in 10-15% of patients. [3]


Experimental sprays were applied to 3 tree plots in a randomized block design consisting of 3 replicates of'Yorking' and 2 replicates of'Golden Delicious' with a buffer row between blocks. These trees were planted to a spacing of 20 × 30 ft and were 16-yrs-old. Experimental sprays were applied with a Friend Airmaster '309' at 50 gpa per alternate side spray (100 GPA-both sides) driven at 2.3 mph. Rates for treatments are listed as amounts/acre/both sides spray. The Diazinon/Insegar treatment received complete sprays for all covers and the RH-5992 treatments received complete sprays on 22 May and 15 Jul. A routine schedule of fungicides (Benlate, Dikar, Nova, and Dithane M-45) was maintained throughout the experiment. For a complete schedule of all treatments, see the first table. Effectiveness on the aphid complex was evaluated by counting aphid-infested leaves/10 top terminals, and aphids/most infested leaf. Effect of sprays on WALH was evaluated by counting nymphs/25 injured leaves/tree. Effectiveness of test chemicals on ERM was evaluated by counting mites several times during the season on samples of 25 random leaves/tree, 100 leaves/treatment. Effect of sprays on the predator S. punctum was evaluated by 3-min counts of adults and larvae around the periphery of test trees. STLM were evaluated by a 5- min count of mines around the periphery of trees at the end of each of the three generations before peak emergence of the next generation adults. TABM were also evaluated with a similar 5-min count of shelters on 11 Jul during the first generation when most larvae were late fourth and fifth instars. Effectiveness of chemicals on fruit feeders was assessed by scoring for injury all drops between 3 Jul and 1 Sep and two picked samples on 21 Aug (35 apples/replicate) and 24 Sep (100 apples/replicate). All lepidopteran larvae from one replicate of each treatment that were found at the time of scoring were placed singly on an artificial lima diet normally used for rearing TABM. These larvae were then reared to adults in sealed 22 ml plastic cups at 25°C and 16:8 LD. Adults were identified to species and parasites noted to give an indication of the proportion of species attacking the apples at various times of the season. Pest pressure was extremely high throughout the season. Fruits were rated as 0 (no russet), 1 (raised lenticels), 2 (1-10% russeted surface), 3 (11-25% russeted surface), 4 (26-50% russeted surface), or 5 (>51% russeted surface). Possible ranges are 0-30 (none to raised lenticels), 31-60 (raised lenticels to 1-10% russeted surface), 61-90 (1-10% to 11-25% russeted surface), 91-120 (11-25% to 26-50% russeted surface), and 121-150 (26-50% to >51% russeted surface).


Presidential addresses are opportunities for considering the current state of, and future prospects for, the discipline. The presidential address in 1996 was titled 'The diversity of the species'. Now, some two years later, as I prepare this address to consider the discipline in the 21st century, it emerges that an alternative title, 'The survival of the species?', would be just as appropriate. What follows is a personal view of the challenges ahead for the discipline, though a literature search indicates that a number of the points to be raised have been considered or alluded to by others in recent years. Whilst we as statisticians have had outstanding successes in many aspects of our discipline in the last three or four decades, there are some notable areas in which I believe our performance falls far short of what it should be, and which we need to consider and to give added emphasis to in the not too distant future. This is imperative if we are to survive as a discipline in our own right, rather than becoming absorbed into a more broadly based group relating to 'information sciences' or 'information services'. When considering changes which must, and will, take place in the future, in an attempt to get some feel for the potential magnitude of these changes, it is interesting to compare the present with the past. For example, consider changes in information technology over the last few decades. Those of us at university in the early 1960s can remember when tables of logarithms and the slide rule were the tools used for calculation. These were followed by mechanical calculators, electronic calculators, programming using punched cards, DOS-based PCs, software requiring the writing of code, and now the menu-driven software packages of today. Four years ago the World Wide Web was virtually unknown; four years on it is providing for network-based statistical analyses. This technology transition has resulted in a transformation from the production of graduate statisticians in the 1960s and 1970s with strong theoretical backgrounds but relatively weak practical experience, to the graduates of today who have had the opportunity to be exposed to realistic practical analyses. It is always interesting to talk to people who were at the forefront of research in statistics following the Second World War. In personal discussion it is surprising to find that so many of them felt they had wasted some of their most productive research years developing algorithms and recursive formulae to enable estimates of parameters to be made, only to find that a decade or so later this work was irrelevant as a result of advances in the speed and capacity of computer technology. What are the lessons to be learnt from this? There is no doubt there is a great deal of concern, nationally and internationally, about the future role of statisticians. Internationally one has only to look at recent American Statistical


From rhizomes of Curculigo orchioideg(Xian Mao)six new cyclo- artane glycosides named curculigosaponin A~F were isolated.The new triterpenoidal sapogenin named curculigenin A,whlch is common to curculigo- saponin A~F,was formulated as 3β,11α,16β-trihydroxycycloartane-24-one by HR-MS and 2D-NMR technical analysis.On the basis of chemical evidence and spectral data,the structures of these saponins were elucidated.


Electronic control is an important measure for roundly improving performance of diesel engines. This paper sets up a new governing system with mechanical electronic control for diesel engines with a mechanical governor changed and a linear electromagnetic actor adopted. The management system based on the control way has effective control functions.The total control system has been operated on an engine bench and a heavy duty truck. The results show that the management system can carry out flexible control and the governing apparatus operate reliably. Performances of the diesel engine with the control system are obviously improved. The governing system is a new one,and its management system need be improved further.


What determines the significance of support among high-income individuals for progressive taxation? Similarly, why do a significant number of low income individuals oppose progressive taxation? For the last decade, the rich's support for and the poor's opposition to redistributive policies have been the focus of intense research in political economy. These studies identify various mechanisms concerning the formation of individual preferences for redistributive policies. Yet, no parsimonious explanation has emerged from this extensive theoretical and empirical discussion. Most accounts assume, incorrectly, that individuals use factual information about income inequality to calculate the expected benefits and losses from prospective taxation policies. This paper challenges that basic assumption. It suggests that in making decisions about taxation policies, individuals often rely on misperceptions of income distribution, income inequality and their standing in the economy; they do not use factual information. With a randomized survey experiment, we show that these perceptions can be affected by presentation of correct information. ∗Prepared for presentation at Preferences over Redistribution Workshop, Duke University. †Email:email@example.com. Department of Political Science, Duke University.


Security administrators face the challenge of designing, deploying and maintaining a variety of configuration files related to security systems, especially in large‐scale networks. These files have heterogeneous syntaxes and follow differing semantic concepts. Nevertheless, they are interdependent due to security services having to cooperate and their configuration to be consistent with each other, so that global security policies are completely and correctly enforced. To tackle this problem, our approach supports a comfortable definition of an abstract high‐level security policy and provides an automated derivation of the desired configuration files. It is an extension of policy‐based management and policy hierarchies, combining model‐based management (MBM) with system modularization. MBM employs an object‐oriented model of the managed system to obtain the details needed for automated policy refinement. The modularization into abstract subsystems (ASs) segment the system—and the model—into units which more closely encapsulate related system components and provide focused abstract views. As a result, scalability is achieved and even comprehensive IT systems can be modelled in a unified manner. The associated tool MoBaSeC (Model‐Based‐Service‐Configuration) supports interactive graphical modelling, automated model analysis and policy refinement with the derivation of configuration files. We describe the MBM and AS approaches, outline the tool functions and exemplify their applications and results obtained. Copyright © 2010 John Wiley & Sons, Ltd.


In medicinal stage, there have vast contrasts between wellbeing seekers and wellbeing specialists. To connect the vocabulary contrasts between two segment specifically neighborhood mining and worldwide mining in which the client post their inquiry on online restorative stage. It helps the client to effortlessly gather data about wellbeing. This paper ties together, neighborhood mining and worldwide learning approach, it codes the restorative record in novel plan. Nearby mining approach attempt to take out medicinal idea from the restorative record itself and code the individual therapeutic record, it helps mapping them towards worldwide learning. At times neighborhood mining approach experiencing data misfortune and low exactness, because of superfluous therapeutic idea and nonappearance of key medicinal idea. Worldwide adapting, of course, work towards overhauling the adjacent therapeutic coding by method for helpfully finding missing key wording and keeping off the unessential expressing by examinations the social neighbors. It keeps up the possibility to social data generous. After careful dissect it acknowledges the propose arrangement and each of its part. Keywords—healthcare; medical terminology assignment; local mining; global mining;


NR-U enables 5G to access the unlicensed bands. However, a 5G NR-U transmitter has to follow the Listen Before Talk (LBT) procedure, where the transmitter has to sense the channel for a while prior to its transmission. Since NR-U is a scheduled technology, the transmission begins only at slot boundaries. But the LBT procedure may end before reaching the slot boundary, and then the transmitter has to wait for a gap period to align with the slot boundary. 5G has different numerologies, and the slot duration of each numerology is different. When nodes with different numerologies are contending for channel access, the node with a lower slot duration has a high probability of winning the channel since, after the LBT procedure, its next slot mostly comes sooner, which leads to fairness issues. In this letter, we propose an algorithm to improve the fairness in multinumerology contention by adaptively changing the Maximum Channel Occupation Time (MCOT) of each numerology according to the slot duration and the number of nodes in each numerology.


Mobile agents are useful in collaborative business systems due to their mobility and autonomy, which can roam over the Internet to purchase goods and services on behalf of their owners. However, given attacks from a malicious host, it is a challenge to securely sign a contract on behalf of the owner (the original signer). In this paper, we propose an intrusion-resilient undetachable digital signature (IR-UDS) approach to mitigate the security risk of signing key leakage on the signer's host, base device, and potentially malicious remote hosts, as well as the risk of misusing the signing algorithm on remote hosts. An attacker will be unable to forge the past and future signatures as long as the base device is secure, even if the current signing key of the original signer has been gained. When the base device is compromised, although the future signatures could be forged, all past signatures remain secure. Furthermore, the encrypted signing function has been combined with the original signer's requirement to prevent the misuse of signing algorithm and the exposure of original signing key on malicious hosts. Security analysis has indicated that our scheme can defeat a variety of attacks, and experimental evaluations have demonstrated the good performance of the scheme.


What is so great about coffee houses? Aside from the obvious appeal of high-priced, unpronounceable beverages available in modern-day coffee shops, in the seventienth century, coffee houses were meccas of significant reform in societal thought. According to The Economist, "coffee-houses were the centre of scientific education, literary and philosophical speculation, commercial innovation and sometimes, political fermentation" ("Internet in a cup"). The popularity of London coffee houses in the seventeenth and eighteenth centuries influenced the start of the Age of Enlightenment in the way that they brought a new beverage to the masses, emphasized social equality by rejecting prejudice, and broke down barriers to create a public sphere for literary inspiration, public opinion and public criticism to form.


Alaska Fisheries Science Center. National Marine Fisheries SeNice. NOAA 7600 Sand Point Way NE. Seattle. Washington 981 J 5-0070 Present address: Korea Ocean Research and Development Institute Polar Research Laboratory. An San. P.O. Box 29. Seoul 425-600, KOREA Oceanic Dispersion of Larval Fish and its Implication for Mortality Estimates: Case Study of Walleye Pollock Larvae in Shelikof Strait, Alaska Abstract.-To estimate mortality and abundance of walleye pollock Theragra chalcogramma. larvae in Shelikof Strait. Alaska. dUling spring 1981, a diffusion-advection model, combined with growth and death of fish larvae, was applied. Physical parameters (diffusion coefficients and advection rates) were derived from the distributional variances and centroids of fish larvae collected in ichthyoplankton surveys. The diffusion coefficient and the advection rate in the along-strait direction were 65.2 km2/day and 2.7-4.2 km/day, respectively, which compared favorably with values obtained from moored current-meter data. Simulation revealed that the expected distribution of larvae was similar to that observed from ichthyoplankton samplings, and that around 20% of the larvae drifted out of the survey area in Shelikof Strait within the I-month sampling period. The larval fraction dispersed out of the survey area was used to revise larval mortality and abundance estimates. Revised mortality (0.070/day) was close to that (O.063/day) determined from examining larval patches. The simulation in this paper resulted in an increase by a factor of 1.5 in the estimated total larval abundance compared with earlier estimates and field observations.


Performances of ventilation systems can fall off because of wind pressure and pressure drops of frosted heat-exchange units. Though performance stability is necessary to maintain indoor air quality and energy saving, evaluation methods of its stability haven't be defined. In this paper, firstly, the calculation methods of airflow and ventilation load in consideration of changes of P-Q curve of a fan and pressure loss among the airflow path is described. Secondly, characteristics of the change in responses to frost and wind pressure are measured. Then, to estimate parameters of airflow and ventilation load calculation referring the above measured characteristics data is tried.


This paper studies the eects of Chinese provincial export variety growth on its technological improvement by applying a monopolistic competition model with endogenous technology. Introducing export varieties into the provincial GDP function with multiple sectors, I esti- mate these eects by exploring a panel data that covers all 31 executive districts of mainland China from 1998 to 2005. The results show that export variety signi…cantly aect productivity growth: it accounts for 44.1% of cross-province TFP dierences and 36.6% of within-province TFP growth; a 10% increase in the export variety of all exporting in- dustries leads to a 1.4% productivity increase in China (as a weighted province average).


Cardiovascular, Part 1 cardiovascular, Part 2 Geriatric Pain and Controlled Drugs Drugs Neoplastic Disorders Gastroenterology Genitourinary Antimicrobials Mental Health, Part 1 Mental Health, Part 2 Muscle Relaxants and Nonsteriodal Anti-Inflammatory Drugs (NSAIDs) Chronic Obstructive Pulmonary Disease (COPD) Ophthalmics Diabetes Miscellaneous Products Supplemental Prescriptions Abbreviation


Background and Objectives:  Hand eczema is a chronic disease with negative impact on quality of life (QoL). In this study, QoL in hand eczema patients is assessed and related to age, sex, severity, and diagnostic subgroups.


Epigenetic like mechanism potentially have a critical role to play in the long term modulation of behaviour, interaction and adaptation. In this study we implement an model of these mechanism, the upward and downward regulation of hormone receptors located in a simply hormone driven autonomous agent. We frame this study in a multi agent setup using competition as a way to change the dynamics of the environment and the challenges the agents face. We found that this simply epigenetic mechanism has the potential to significantly alter the behaviour of the agents, allowing them to develop not only unique individual behaviour but also group like structures that permit them to better adapt to the different challenges that the environment presents.


The utility model relates to a plastic pipe, specifically relating to a reinforced plastic pipe. The reinforced plastic pipe consists of a pipe body, wherein an inner plastic layer is disposed inside the pipe body, the external of the plastic pipe is provided with a stainless steel mesh, the stainless steel mesh is provided with an external plastic layer, and the inner plastic layer, the stainless steel mesh and the external plastic layer are integrated. To go one step further, the stainless steel mesh is formed by interweaving circular stainless steel wires and strip-shaped stainless steel wires, the diameter of the circular stainless steel wires is larger than the strip-shaped stainless steel wires. The plastic pipe has the advantages of high strength, low cost and easy manufacture.


Current  maritime  transportation  and  shipping  is  characterized  by  rapid  technological developments  effecting  the  basic  concepts  of  operating  ships  and  even  changing  traditional  paradigms  of controlling ships. The e‐Navigation concept of the International Maritime Organization (IMO) specifically aims at  more  comprehensive  and  reliable  support  of  the  human  operators  on‐board  and  ashore.  However, autonomous unmanned ships remote controlled or even autonomously navigating are expected to come soon. In  this  paper,  selected  operational  aspects  of maritime  traffic merging  conventional  and  unmanned  remote controlled  ships  in  coastal  areas  are  discussed.  Furthermore,  some  preliminary  results  of  experimental simulation  studies  into  a  future  scenario  of maritime  traffic  are  presented  and  preliminary  conclusions  in respect to job profiling and training requirements are discussed. http://www.transnav.eu the International Journal on Marine Navigation and Safety of Sea Transportation Volume 13


Background: Newer troponin assays offer the ability to quantify circulating troponin levels at an order of magnitude lower than contemporary assays, fueling continued debate over the prognostic implications of very low-level increases in concentration. We evaluated the prognostic implications of low-level increases in cardiac troponin I (cTnI) using an investigational single-molecule high-sensitivity assay in patients with acute coronary syndrome (ACS). Methods: We measured cTnI using both a high-sensitivity troponin I (hsTnI) assay (Erenna, Singulex, 99th percentile 9 pg/ml) and a current generation sensitive assay (TnI-Ultra, Siemens, 99th percentile 40 pg/ml) at baseline in 1807 patients with non-ST elevation ACS and compared their prognostic ability for adverse cardiovascular events at 30 days and one year. Results: Among patients with TnI-Ultra<99th percentile, patients with elevated hsTnI (≥9 pg/ml) had a significantly higher risk than patients with hsTnI<9 pg/ml: cardiovascular death (CVD) or myocardial infarction (MI) at one year (7.0% vs 3.8%; p<0.001, hazard ratio (HR) 2.05, confidence interval (CI) 1.23–3.41); including a higher risk of CVD (3.5% vs 1.5%, p<0.001) and MI (5.0% vs 2.8%, p<0.001) individually. This higher risk of CVD/MI was independent of clinical risk stratification using the TIMI Risk Score (adj. HR 1.76, CI 1.05–2.90). Moreover, hsTnI showed a trend toward a gradient of risk even below the hsTnI 99 percentile. Conclusions: Low-level cardiac troponin detected using a single-molecule technique, below the cutpoint of a contemporary sensitive assay, identified a significant gradient of risk. These findings support the prognostic relevance of low-level cardiac troponin elevation with increasingly sensitive assays in patients with ACS.


Ultrasonic Doppler signals are widely used in the detection of cardiovascular pathologies or the evaluation of the degree of stenosis in the femoral arteries. The presence of stenosis can be indicated by disturbing the blood flow in the femoral arteries, causing spectral broadening of the Doppler signal. To analyze these types of signals and determine stenosis index, a number of time-frequency methods have been developed, such as the short-time Fourier transform, the continuous wavelets transform, the wavelet packet transform, and the S-transform.


A two‐way selection was performed in mice according to the quantitative in vitro response of lymph node lymphocytes to the mitogenic activity of phytohemagglutinin (PHA).


The invention discloses a deflection mechanism of a fan blade hoister for a wind driven generator. The deflection mechanism of the fan blade hoister for the wind driven generator is used for assisting in adjusting the gesture of fan blades during fan blade mounting and dismounting through the fan blade hoister in an aloft unsupervised state and is simple in whole structure, convenient to use and high in automation degree, and manual interference is not needed. Compared with existing deflection mechanisms, the phenomenon that the deflection mechanism gets stuck due to inclination of gravity centers of hoisted objects is not liable to occur. The deflection mechanism comprises tracks, a movable trolley, a lead screw, a motor, a speed reducer and a nut. The transversely arranged lead screw is sleeved with the nut. The lead screw penetrates through the movable trolley and is fixedly connected with the movable trolley through the nut. Rolling wheels are arranged at the bottom of the movable trolley and are placed on the tracks. The tracks and the lead screw are in parallel in the axial direction. The output end of the motor is connected with the speed reducer. The lead screw penetrates through a hole in an output shaft of the speed reducer and form a 90-degree included angle with the output shaft of the speed reducer. The speed reducer drives the lead screw to rotate, and the movable trolley does linear movement along the tracks.


t often seems that the most intense visual stimulus in a child's world is a moving image on a television screen. Certainly, children seem to be much more attuned to this moving picture than to the stark, silent images on the wall of a museum; they respond spontaneously to movies and TV but must be taught to appreciate paintings. The forbidding atmosphere in which most children are exposed to visual art does not contribute to a positive experience; they are told in no uncertain terms to look, but DO NOT TOUCH! In the spring of 1983, the Firelands Association for the Visual Arts (FAVA, Oberlin, Ohio) sent an outreach program (What Color is Your Smile?) designed to make painted images more accessible to young people in 24 elementary schools. The concept of this program was to engage all five senses, not just sight, in the appreciation of art. The program had three stages: Preparatory sensory activities led by the children's classroom teacher, a session with a FAVA instructor, a take-home booklet, and post-program activities. Pre-program activities were intended to make the children more keenly aware of their senses through such exercises as the "Smell Game." The children gathered herbs, grasses, spices, dried fruits, and flower petals, placing each item in its own container. As they passed the containers, they tried to visualize the object from its odor. Favorite and least favorite smells were discussed, as was the effect of smell on perception. What if a rose smelled like a rotten egg? The children drew pictures to show what the world would be like if the expected relations between odors and their sources were altered. The first part of the FAVA instructor's visit furthered the children's awareness of self and environment. They were asked to focus on each of their senses in isolation; closing their eyes, they listened to their breathing and heartbeat. They took a deep breath, and smelled spring in the air; they touched their clothes and their skin to compare their textures. The instructor asked them to taste their skin to see if it was salty. Finally, the children opened their eyes and looked carefully at their hands, searching for variations in color and texture. From the realm of sensory awareness, the instructor moved to that of sensory imagination. Following the instructor's example, the children turned their classroom walls into chocolate, light fixtures into clouds, flooring into oceans, and the teacher into an ice cream cone, all in their minds. (This exercise was inspired by De Mille, 1973). Another exercise dealt with correspondences between color and other sensations. The children suggested that rushing water is electric blue, that a gunshot is bright red, and that a racing car is a streak of brilliant yellow. Still other exercises had the children scrutinize everyday objects in terms of their sensory properties of color, texture, smell, etc. With sensory awareness heightened, the children turned to art. Reproductions of five or six paintings, ranging from highly representational works such as Grant Wood's Paul Revere's Ride (1931) to more abstract pictures such as Joan Miro's Seated Woman I (1938), hung in the room. Students were asked to imagine they were inside one of the paintings. The instructor posed questions, encouraging the children to answer them in pantomime as well as in words: Where in the painting are you? What are you doing? Are you alone? Is it day or night? Warm or cool? Winter or summer? Now or long ago? What are you wearing? What kinds of sounds, smells, tastes, and textures are there in the painting? By conceiving of the painting as an environment rather than simply as a picture, they were able to enter into it physically, sensorally. In the last phase of the classroom visit, the children made drawings of their own. As the instructor narrated a story replete with sensory detail (e.g., a walk through the woods), the children closed their eyes and projected themselves into the situation described. They then illustrated their experience with drawings. In addition to these classroom sessions, each child was given a booklet to work on at home. Each page repre-


Cell-to-cell communication pathway of single-celled microbes is usually coordinated by quorum sensing (QS) system mediated by signal molecules. This cell density-dependent system plays a vital role in functional coordination of most pathogenic bacteria. Antagonistically, interruption of this signal pathway by inactivating the signal molecules through quorum quenching (QQ) could be an alternative strategy to control bacterial virulence. In this study, a local soil isolate identified as Bacillus cereus SM01,has been shown to possess the capability of enzymatic inactivation of acyl homoserine lactones (AHLs). This special trait of SM01 prompted the interest in testing its potential quorum quenching ability. Hence, the amplified 770 bp long AHL-lactonase gene homologue (aiiA) of SM01 was subsequently cloned into pCold expression system in order to express the desired recombinant AHL-lactonase protein. Further characterization of that the overexpressed 29 kDa recombinant protein revealed that it drastically decreased biofilm formation of Burkholderia pseudomallei UKMS-01 strain, an animal pathogen. Interestingly, the recombinant AHL-lactonase protein was observed to be stable up to 85oC in temperature where most of the enzymes will be inactive. Nevertheless, it showed wide range of pH stability, from pH 5 up to 11. All these characteristics suggest that this recombinant AHL-lactonase has the potential to be used as a commercial enzyme for the control of pathogenic bacterial infection.


Parameters affecting antibody conjugation with immunomagnetic beads (IMB) are investigated when Goat antiMouse IgG/HRP is used as a model antibody. Results found that antibody could be conjugated on the surface of magnetic beads (MB) by physiochemical adsorption and covalent bonds. The polystyrene/acrylamide magnetic beads (amino-MB) could bind more antibodies than polystyrene/acrylic acid magnetic beads (carboxyl-MB) when the concentration of antibodies ranged from 0.25 to 1.0mg/L. For amino-magnetic beads, the conjugation amount of antibodies increased gradually as the antibody to MB ratio increased from 5 to 20mg/g, while the value of antibodies kept stable when the ratio increased to 30 from 20mg/g. It is also found that the conjugation amount of antibodies increased rapidly in the first 1h and then kept unchanged the followed 1hr at the ratio of 20mg/g. There is a significant difference between conjunction amount of antibodies of IMB prepared with Tris buffer and Carbonate buffer solution (CBS). The maximal conjugation amount of antibodies on the amino-magnetic beads' surface is 3.66mg/g when 2h incubation supplied with Tris buffer. The buffer also affects the dispersion of IMB. The dispersion of IMB prepared with CBS is better than that with Tris buffer before washing by TBST, while it is adverse after washing.


Generally such children can be divided into two main categories-the &dquo;educable mentally retarded&dquo; and the &dquo;trainable.&dquo; This differentiation derives from educators' use of intelligence tests such as those of Binet, Wechler and others. These tests determine what is called the mental age (M.A.); comparing this with the child's chronologic age (~.~=~.) gives the intelligence quotient (I.Q.). In the formula NI.A./C.A. = I.Q. the average child should have a ratio czf about 1:1 and an I.Q. of about 100. Children whose i1=L.~, is less than threefourths of the ~. ~. (I.Q. less than 75) are consid. ered retarded in classical educational terms. Further subdivision into educable and trainable groups depends upon I.Q. scores too. Children with an I.Q. of less than 50 are viewed as &dquo;traiz~able,&dquo; whereas those between 50 and 75 are &dquo;educahle.&dquo; Such division may seem unnecessarily arbitrary and rigid, but experience has shown it to be useful in the educational world. With proper programs most educable children do achieve semi-independence in adulthood and can live happy and successful lives with a minimum czf exogenous help. They may complete 12 years of public school education in special education or &dquo;modified&dquo; classes. In contrast, the trainable children require continuous external supervision and may have to have a great deal of care throughout their lives. They rarely can be placed in any kind of classical public school program wherein group instruction is basic. Both the educable and the trainable children can, of course, live at home.


Microfluidic experiments and simulations reveal an anomalous percolation transition for the flow of a yield stress fluid through a random porous medium. The evolution of the fluidized network results in a highly nonlinear flow conductivity and reveals a novel dispersion mechanism.


While science is taken to differ from non-scientific activities in virtue of its methodology, metaphysics is usually defined in terms of its subject matter. However, many traditional questions of metaphysics are addressed in a variety of ways by science, making it difficult to demarcate metaphysics from science solely in terms of their subject matter. Are the methodologies of science and metaphysics sufficiently distinct to act as criteria of demarcation between the two? In this chapter we focus on several important overlaps in the methodologies used within science and metaphysics in order to argue that focusing solely on methodology is insufficient to offer a sharp demarcation between metaphysics and science, and consider the consequences of this for the wider relationship between science and metaphysics.


— In this paper, ANN controller for maximum power point tracking of photovoltaic (PV) systems is proposed and PV modeling is discussed. Maximum power point tracking (MPPT) methods are used to maximize the PV array output power by tracking continuously the maximum power point. ANN controller with hill-climbing algorithm offers fast and accurate converging to the maximum operating point during steady-state and varying weather conditions compared to conventional hill-climbing. The proposed algorithm gives a good maximum power operation of the PV system. Simulation results obtained are presented and compared with the conventional hill-climbing algorithm. Simulation results show the effectiveness of the proposed technique.


Bistatic SAR is a potential and effective tool for ocean remote sensing, and the simulation of bistatic SAR raw data from ocean surface plays a great role in the understanding of the mechanism of bistastic SAR ocean surface imaging. In this paper, a bistaitc SAR raw data simulation model for ocean surface is presented, which includes bistatic scattering simulation and ocean echo data simulation. In our research, based on IEM scattering model, a stochastic multiscale scattering model is improved by applying the second order nonlinear modulation model, and the speckle noise and coherent time character of ocean surface are simulated in the SAR raw data simulation.


The present work describes the photoconductivity dependence on ZnO nanostructure UV sensor. ZnO nanostructures were synthesized by direct vapor phase (DVP) technique. ZnO nanowires are of dimensions 30-65 nm in diameter and 5 μm in length. The role of oxygen in deciding the opto-electronic properties of nanostructured ZnO UV sensors was studied.


The necessity of air-conditioning causes the enormous energy use of underground train stations. Exergy and thermoeconomic analysis is applied to the annual operation of the air-conditioning system of a large underground train station in Taiwan. The current installation and the monitored data are taken to be the base case, which is then compared to three different optimized designs. The total revenue requirement levelized cost rate and the total exergy destruction rate are used to evaluate the merits. The results show that the cost optimization objective would obtain a lower total revenue requirement levelized cost rate, but at the expense of a higher total exergy destruction rate. Optimization of thermodynamic efficiency, however, leads to a lower total exergy destruction rate, but would increase the total revenue requirement levelized cost rate significantly. It has been shown that multi-objective optimization would result in a small marginal increase in total revenue requirement levelized cost rate, but achieve a significantly lower total exergy destruction rate. Results in terms of the normalized total revenue requirement levelized cost rate and the normalized total exergy destruction rate are also presented. It has been shown by second law analysis when applied to underground train stations that lower annual energy use and lower CO2 emissions can be achieved.


It is shown that an external electric field E3 (even if it is arbitrary weak) can induce an incommensurate phase in the crystal. The components M1 and M2 of the magnetic moment Mi are chosen as the order parameter components.


In this paper,the effect of the extrudation moisture regain on concentration and viscosity of the size paste is studied,and some factors which influence the extrudation moisture regain are discussed.The results show that the size paste has better concentration and viscosity stability,and sized yarn has better quality if the extrudation moisture regain is controlled in 40 percent for cotton and polyester cotton blended yarn.


Crit Care Med 2015 • Volume 43 • Number 12 (Suppl.) and acetaminophen were the most common offending drugs causing bradycardia (propofol 32.1% and fentanyl 12.5%) and increased aspartate transaminase (acetaminophen 5.8%). Of the probable/definite ADRs, fentanyl, insulin, and dextrose were the most common offending drugs causing hyperglycemia (fentanyl 24.6% and dextrose 4.3%) and hypokalemia (insulin 18.8%). Conclusions: ADRs in patients undergoing TH after cardiac arrest are common. Select agents should be used judiciously and monitored closely in this setting as a result of the possibility of ADRs.


1
Introduction

2
Elemental Analysis

3
Amines

4
Quaternary Ammonium Compounds

5
Nitro Compounds

6
Nitroso Compounds

7
Hydroxylamines

8
Amino-Oxyls

Keywords:

Automatic Organic Elemental Analysis (CHNOS);
nitrogen responsive detectors for GC;
digestion methods;
stable isotope analysis;
amines and liquid chromatography;
quaternary ammonium compounds;
nitro compounds and polycyclic aromatic hydrocarbons (PAH);
nitroso compounds


Undoubtedly, apocalyptic literature is among the difficult literature to understand and to interpret due to its literary genre and mode of communication which is often in the form of visions. Though weird symbols and images shrouded in secrets and coded language are the content of these visions, the literature [those in the Judeo-Christian Scriptures] has been both an inspiration and a mystery to Christians in particular and Ghanaian Christians in general. Apart from serving as a motivational tool for Christians to know that true authority and power belongs to God, and among others, the literature also offers hope to Ghanaian Christians of the impending judgment at the end of this age. Though the literature has not been rightly handled by some Ghanaian pastors and Christians, the unending effect has made people hope in the Lord. This paper, therefore, contributes to the general knowledge of apocalyptic literature and accentuates how its message in the Judeo-Christian scriptures have greatly influenced the beliefs, lifestyle, and thought pattern of Ghanaians in general, and contemporary Christianity in Ghana, in particular; making them live in consonance with the message of the biblical apocalyptic literature which encourage them to develop a certain kind of belief, thought pattern, and lifestyles different from an ordinary individual, and not otherwise.

Keywords: Apocalyptic literature, apocalypse, apocalypticism, apocalyptic eschatology, Ghanaian Christianity


Lack of baseline biodiversity information is widely recognized as a major barrier for identifying temporal changes in landscapes either due to anthropogenic activities or other factors crucial for the management and conservation of biological resources. We present here results of our study conducted in Salkhala game reserve between February to July 2016, Azad Jammu & Kashmir, Pakistan to set baseline on diversity and distribution of butterflies. Five transect of 500m length each were laid down in different habitat type and along altitudinal gradient to record butterflies. A total of 38 species were recorded where two most abundant recorded species were Indian Red Admiral ( Vanessa indica ) and White-Line Hairstreak ( Strymon assamica ) with n=54 individuals each and the least recorded species were Blue Peacock ( Papilio arcturus) and Common Windmill ( Atrophaneura polyeuctes ) which recorded n=34 individuals. Forest cuttings, grass cuttings, unsustainable utilization of natural Resources, lack of conservation awareness, unmanaged grazing were recorded as the major threats to the butterflies' fauna. Established survey plots provide baseline to be used to monitor the butterfly diversity in future. Development of a conservation and management plan for the game reserve would be of great value towards management of biodiversity in the study area.


In Fei Ming's opinion, the difference between classical poetry and free verse firstly consists in content: the former content belongs to that of prose while the latter that of poem; secondly, in writing: the former is the writing of poem, but the latter is of the prose. Poem is a style of literature in which its content can be expressed freely, purely and completely by using the writing of prose.


Abstract Strawberry (Fragaria x ananassa Duchense ex Rozier) is an important horticultural crop grown in Latvia. The aim of this research was to evaluate some newly introduced strawberry cultivars and perspective hybrids and to evaluate the efficiency of natural calcite leaf fertiliser (Megagreen®) on strawberry fruit quality and spread of pests and diseases. The trial was established in 2012 at Pûre, Tukums Municipality. Cultivars 'Saint Pierre', 'Annapolis', 'Sonata', 'Chambly', 'Elegance', 'Rumba', 'Honeoye', 'Senga Sengana' and two hybrids: 35-1 and 39-1 were included in the investigation. Calcite fertiliser was applied four times per season in 2013 and 2014 by spraying on leaves in concentration 0.5%. Strawberries were grown on two row beds with black plastic mulch and drip irrigation. The evaluation was done for two seasons. Most of the evaluated newly introduced cultivars and hybrids had better fruit quality and resistance to diseases than control cultivars. Cultivars 'Annapolis', 'Rumba', 'Sonata', 'Elegance', and 39-1 were selected as the most promising related to fruit quality and resistance. The application of calcite fertiliser (Megagreen®) on leaves had no statistically significant effect on strawberry fruit quality and resistance.


Abstract Separation of hydrogen isotopes has been successfully demonstrated using bipolar electrolysis combined with electrolyte flow countercurrent to the transport of hydrogen isotope species. Use of multibipolar electrode cells in a squared-off cascade is shown theoretically to be capable to efficient tritium separation. Experimental operation of multibipolar cells and analysis of their operation by McCabe-Thiele techniques is described.


Objective: is study evaluated the reliability and validity of the Attachment–Caregiving Balance Scale which measures mothers' "attachment" and "caregiving" toward their children. Methods:A self-administered questionnaire was completed by 630 mothers who had children aged 1 month old, 6–11 months old, and/or 18 months old. e survey was conducted to assess the reliability and validity of the Scale using six factors (the factors of "adaptability," "sensitivity," and "intimacy" for each of the "attachment" and "caregiving" categories) and other external indices. Results:Cronbach's α was 0.882, and exploratory factor analysis found a factor structure quite similar to what was expected. e results of con rmatory factor analysis were a goodness of t index value of 0.842, an adjusted goodness of t index value of 0.812, and a root mean square error of approximation value of 0.074. Signi cant di erences were found by known groups analysis, and there was also a signi cant correlation, albeit below 0.7, with the external indices. Conclusion:While criterion-related validity should be further examined, reliability and construct-related validity were supported, indicating that the scale can be used to measure the development of mothers as caregivers.


28 T he Large Hadron Collider (LHC) is a 26.7 km circumference, high-energy proton and ion collider [1] in operation at CERN to serve the world's physics community. The LHC is also the single largest application of superconductivity and helium cryogenics to date, with its 8310 superconducting magnets of all types, most of which are operated at 1.9 K in some 100 tons of superfluid helium. High-field magnets using low-temperature superconductors Superconductivity and helium cryogenics have become key enabling technologies for high-energy accelerators over the last decades [2]. For a given beam energy, the diameter of a circular accelerator scales inversely with the field in the bending magnets: making the latter superconducting thus renders the machine more compact, QUANTUM FLUIDS AT WORK: SUPERCONDUCTIVITY AND SUPERFLUID HELIUM AT THE LARGE HADRON COLLIDER


The effects of AM fungi on protective enzymes in the leaf of Atractylodes macrocephala were investigated by Glomus mosseae under different nitrogen levels in unsterilized soil. Pot experiment and analyses were carried out. The results showed that mycorrhizal infection rate could be promoted by inoculation. The activity of protective enzymes was closly related to the inoculation effect of AM fungi and applied nitrogen levels. There was a posityve relation between AM fungi and amount of nitrogen application,and the growth of host plant would be promoted with the positive relation positive.


Explores the relationships between organizational communication and organization theory. Focuses on interorganizational communication and assesses several models of interorganizational relations. Proposes and discusses a method for studying interorganizational communication.


The frequency shifts predicted by the 'relativistic' Doppler effect are derived in the photon picture of light. It turns out that, in general, the results do not depend exclusively on the relative velocity between observer and light source. In this respect, the relativistic Doppler effect is not distinct from the classical one, where the shifts are also different depending on whether the source or the observer moves. The 'relativistic' formulae for these two cases have been confirmed by experiment and are described in many textbooks. It was, however, not recognized that they are at variance with Einstein's relativity principle extended to electromagnetic waves.


A Non-governmental organization (NGO) is a voluntary group of individuals or organizations, usually not affiliated with any government, that is formed to provide services or to advocate a public policy. Although some NGOs are for-profit corporations, the


Mercury emission in coal-fired flue gas has become one of the most important environmental issues now.The paper discusses the status and progress of mercury removal technology in coal-fired flue gas,and introduces the effects of SCR technology on mercury removal in flue gas.The insoluble gaseous mercury in flue gas is catalyzed to water-soluble oxidized mercury over SCR catalysts and then removed by wet flue gas desulfurization devices.


Objective:To explore the application of retroauriclar groove flap in reconstruction of ear.Method:A retroauricular groove flap with pedicel was designed to reconstruct retroauricular groove.Result:36 cases of retroauricular groove flap through this surgery were survived,and reconstituted auricles had obvious skull-auricles angle,the symmetry of reconstituted auricles were improved.Conclusion:This method of retroauricular groove flap can maintain skull-auricle angle of reconstituted auricle,overcome the defect bringed by contraction of dissociative skin graft,and improve the aesthetic feeling of reconstituted auricle.


[Objective]To evaluate the effect of integrated management of blood loss in total knee arthroplasty (TKA ) between gypsum fixed up, ice compress,elastic bandage and only with elastic bandage. [Methods]From January 2006 to August 2008,107 patients undergoing TKA were randomized divided into integrated management group( 54 cases) and control group( 53 cases).Sex,age and deseases in two groups were comparative.The patients in integrated management were treated with elastic bandage,gypsum fixed up,leg elevated by 35 degrees at the hip with knee extended, continuous cold therapy.The patient in control group were only treated with single elastic bandage.The loss of blood during 2 h, 12 h, 24 h postoperative were analyzed.[Results]The blood loss was 170 ml(85~505 ml),210 ml(105~560 ml), 260 ml(110~580 ml)at 2 h、12 h、 24 h postoperative in integrated management group,and 180 ml(110~900 ml), 320 ml(115~930 ml),390 ml(170~970 ml) in control group.The blood loss in integrated group was obviously and a statistically significant difference was found between the two groups (P0.001).[Conclusion]The blood loss of patients in TKA is obviously lower in the integrated management. It coule decreas the blood loss by 33.3%.


One of the challenging issues in aerospace industries is to configure a SHM solution for ageing aircraft structures. This is because of the lack of information regarding the current state of material properties and the higher likelihood of damage to occur. Principally, when classical NDT actuators/sensors are embedded onto/into structures to perform real-time monitoring of tolerable damages, a SHM-solution is obtained. However, in reality this is not that much easy to be realised since most of the NDT techniques are off-line methods meaning they are human based and not implicitly ready for automation. Classical ultrasonic NDT methods like phased array ultrasonics have undergone technological innovations in terms of data acquisition and data representation through the development of Sampling Phased Array (SPA) and Reverse Phase Matching (RPM) methods. These methods have advantages in determining in-situ material properties and result in a comparatively higher probability of damage detection. Unlike the classical ultrasonic methods, where transducers can be virtually moved to any location on a structure, guided waves (GW) based actuation and sensing in SHM is fixed to a 'static' actuator/sensor network. In order to detect damages considered to be tolerable efficiently the optimal positions of actuators/sensors need to be identified in advance. To identify those optimal positions numerical simulation is indispensable, allowing something to be generated called differential imaging, that identifies where damage related sensor signals are to be recorded best. Laser Doppler Vibrometry (LDV) has proven to be another efficient tool for monitoring in the recent years often to be used as a means for validation. In addition to this, linear/nonlinear vibrational acoustics combined with thermography have shown a large potential in identifying particular types of damage where the response has been monitoring representative frequencies based on Local Defect Resonance (LDR). When such LDR frequencies are used to excite the ultrasonic actuators, the signal received from the sensors will be sensitive to the given damage to which the LDR frequency refers. This paper will present how a 'toolbox' has to be configured such that approaches used in classical NDT including SPA, RPM and LDR along with numerical simulations can be applied to design SHM system solutions for monitoring isotropic and anisotropic structural parts.


Deep‐water renewal in Lake Baikal (Siberia), the world's deepest lake and largest lake by volume, is relatively fast. Water age calculated from tritium and helium as well as from chlorofluorocarbons does not exceed 19 yr. Relative saturation of dissolved oxygen typically exceeds 80%. The equation of state of Baikal water was determined including the effect of dissolved ions and silicic acid. Based on nearly 600 CTD profiles taken between 1993 and 1995, two mechanisms of deep‐water mixing were identified. (1) In spring, cold and relatively saline water from the Selenga, the major inflow to the lake, forms a density plume that reaches the bottom of the central basin during April and early May. Due to entrainment of lake water the plume transports about 125 km3 of water per year to the deepest part of the basin. Later in spring, the river water forms the thermal bar observed along the eastern shore. There are indications that parts of the Selenga are also plunging to the deep part of the southern basin. (2) At Academician Ridge, separating the cold and "saline" water of the central basin from the warmer and slightly less saline water of the northern basin, horizontal mixing results in a water mass that can sink on either side of the sill. Whereas in the central basin the water mass stays at intermediate depth, in the northern basin it sinks to the deepest part. More detailed data are needed to quantify this density flux. No indication of a wind‐induced thermobaric instability was found.


One of the greatest challenges facing medicine in the 21st century is comorbidity, where two or more diseases occur together in the same individual. The World Health Organization estimates that two-thirds of people >55 years of age with a chronic disorder have more than one illness at the same time. Comorbidity of depression and anxiety disorders with physical illness is particularly frequent. Lifetime prevalence of depression is between 2% and 15%, and growing; and people with chronic physical illness or long-term conditions (LTCs) are two to three times more likely to suffer from depression than people without physical health problems. This leads to significantly greater reductions in health status.1 In addition, people are likely to have multimorbidity, with several LTCs, which increases complexity of management.2

There are numerous interactions between depression and LTCs (Box 1). It is suggested that up to 30% of patients with diabetes also have depression, with over half of these patients reaching diagnostic criteria for major depression.

Box 1.
### Possible interactions between depression and long-term conditions

People with physical illness:

Depressive disorders may:

Patients with depression may present with a variety of symptoms, for which current medicine finds no organic cause. The more numerous such symptoms, the more probable is the diagnosis of depression.

The relationship between diabetes and depression is complex. Current research suggests that each disease …


We can say that we are surrounded by the computing world from every nook and corner. Cloud Computing is deemed as the most fundamentally changing phenomenon happening in Information Technology. But with great perks, comes great challenges as well, especially in the field of data security and privacy protection. The Cloud Service Providers take over chunks of private data from users for providing better functionalities. But for the sake of privacy and protection, this sensitive data should be encrypted and then outsourced to the cloud consoles.

Since traditional cloud computing is performed on plaintext, many encryption algorithms were applied in the cloud for security purposes and 'encrypted' data was stored in the cloud from then on. This change gives fruition to a new type of encryption technique called Homomorphic Encryption. Primarily, the paper will focus on a subtype of Homomorphic Encryption called Fully Homomorphic Encryption. The objective of the paper is to propose a method to convert the sequentially processing Fully Homomorphic Encryption into parallel processing Fully Homomorphic Encryption using a Parallel Computing concept called Partitioning and thereby producing a better performing Fully Homomorphic Encryption.


Quasi-phase-matched second-harmonic generation of visible light in optical waveguides is a promising source of blue-green coherent light that may have applications to optical disk storage systems. Bierlein, et al. [1] have studied periodically segmented waveguides in KTP and have demonstrated that it is possible to efficiently generate blue-green light. A typical structure consists of an array of ion-exchanged regions with refractive index n0 + Δn, that is embedded in a medium with refractive index no, as shown in Fig 1. This structure is unconventional because guiding and unguiding sections alternate. Extremely low loss has been experimentally observed in these devices, indicating that guiding does exist despite the segmentation [1]. In this paper, we show that within the limit of the paraxial approximation and neglecting back reflections, lossless guided Bloch modes exist and we numerically determine the propagation constants and mode structures.


THE study of rheumatic fever has been an outstanding example of the success of modern investigational methods in medicine. The early clinical and epidemiological studies of Longcope, the serological studies of Coburn and Pauli and the Caveltis, the immunological studies of Rich and the practical application of all of this in the establishment of prophylaxis, particularly by Rammelkamp, are some of the highlights of a brilliant series of investigations, and the results have led to a remarkable fall in the incidence and recurrence rate of this disease. Yet there are still deficiencies in knowledge of the exact nature of its complicated pathogenesis and of means of controlling the disease process, once established. The results of another painstaking and informative study' are, therefore, of considerable interest. It was carried out by the staff of Irvington House, New York, and was primarily set up to investigate the relative merits of three prophylactic regimes: (a) benzathine penicillin, 1,200,000 units given intramuscularly once a month; (b) buffered potassium penicillin G, 200,000 units given orally once daily, half an hour before breakfast; (c) sulphadiazine, one gramme given orally once daily. There were 451 patients, each of whom had suffered a previous attack of rheumatic fever. All were seen monthly for five years, and clinical examination, throat swabbing and serological estimation of antistreptolysin 0 (ASO), antihyaluronidase (AH) and antistreptokinase (ASK) titres were carried out. Streptococcal infection was diagnosed on clinical features, positive finding from throat swab or rise in antibody titre, or any combination of these. Altogether there were 47 recurrences of rheumatic fever and 285 streptococcal infections-a ratio of 16'5%. Expressed in another way, there were 17 infections and 3 rheumatic recurrences per 100 patient-years. It should be noted at once that this rheumatic attack rate per infection, despite the prophylaxis given, is much higher than the 3% which might be expected in normal children suffering a streptococcal infection, a finding which confirms the significance of a host factor in the rheumatic patient. There was a clear-cut answer to the investigators' primary question. Prophylaxis by penicillin given intramuscularly was significantly more effective than that by


The paper presents optimization of the generalized velocity components (GVC) in order to obtain the energy efficient profile. The GVC arise from decomposition of the system mass matrix and the corresponding equations of motion are first-order. The obtained optimal quantities show some properties of the system that are not observable if the system is described using the second-order differential equations of motion. As a result, an insight into the system dynamics can be given and nonlinearity evaluation and reduction is possible. The presented approach was tested analytically and in simulation on a 2 DOF planar mechanical system.


In order to meet the need of the social development,combining the actual conditions,a triable Scheme on teaching reform has been made out in the travel and hotel management deparment of our College.This teaching reform scheme has been analysed and predicted to demand of qualified talents in the travel and hotel management major especially,according to social backgrounds and trade backgrounds of the professional reform in local area,Proposed the goal of the professional reform and basic thinking,adopting the teaching mode of " five ones ",and structured the characteristic professional teaching system,the supporting policy of professional teaching reform and the ensuring measures.


The investigation of the thermodynamic state of the air plasma flow produced by the SCIROCCO arc-jet facility was performed by means of the high resolution optical emission spectroscopy (OES) technique. The line-of-sight emission was recorded 44 cm away from the exit section of the nozzle (0.4 nozzle diameter). Emission spectra are dominated by the NO vibrational bands belonging to the NO-γ (   