Poverty and exclusion lie at the center of social debate in modern democratic societies regulated by welfare-states. In recent years in Europe, exclusion has even become a familiar notion, recurrent in news commentaries, in programs for groups thought to be underprivileged and in policies adopted by EU member-states and the European Commission. Exclusion like poverty is a notion that is not defined in the field of public interventions independently of research in the social sciences. A break should, however, be made with the way these notions are used in current debate, but without rejecting them. The ideas conveyed by these notions and the reality to which they, sometimes confusingly, refer are a subject for sociological inquiry. A start must be made by deconstructing them; and then an object must be reconstructed that, though close to them, stands apart. To this end, three ideal types of interdependence between the groups labeled as "poor" or "excluded" and the rest of society are proposed: integrated poverty, marginal poverty and disqualifying poverty.


Battery management during prelaunch activities has always required special attention and careful planning. The transition from nickel-cadium to nickel-hydrogen batteries, with their high self discharge rate and lower charge efficiency, as well as longer prelaunch scenarios, has made this aspect of spacecraft battery management even more challenging. The AXAF-I Program requires high battery state of charge at launch. The use of active cooling, to ensure efficient charging, was considered and proved to be difficult and expensive. Alternative approaches were evaluated. Optimized charging, in the absence of cooling, appeared promising and was investigated. Initial testing was conducted to demonstrate the feasibility of the 'Adiabatic Charging' approach. Feasibility was demonstrated and additional testing performed to provide a quantitative, parametric data base. The assumption that the battery is in an adiabatic environment during prelaunch charging is a conservative approximation because the battery will transfer some heat to its surroundings by convective air cooling. The amount is small compared to the heat dissipated during battery overcharge. Because the battery has a large thermal mass, substantial overcharge can occur before the cells get too hot to charge efficiently. The testing presented here simulates a true adiabatic environment. Accordingly the data base may be slightly conservative. The adiabatic charge methodology used in this investigation begins with stabilizing the cell at a given starting temperature. The cell is then fully insulated on all sides. Battery temperature is carefully monitored and the charge terminated when the cell temperature reaches 85 F. Charging has been evaluated with starting temperatures from 55 to 75 F.


Introduction: In otolaryngology of the head and neck surgery; differential diagnosis is a practical and comprehensive guide that is organized uniquely by signs and symptoms instead of by diseases. Aim : This study will describe the keys to diagnostic evaluation and differential diagnosis of presenting symptoms for problems affecting each otolaryngology organ system. Methods : Each symptom opens with the patient's presentation followed by an easily accessible list of potential diagnoses and supplementary data on the features of the different diseases to help correctly identify the problem. And identify features labeled by signs and symptoms, not by disease, and then enable quick clinical reference In-depth coverage of the diagnostic and treatment evaluation of all ENT disorders.


Summary. Partial adentia is a topical issue in modern dentistry. Rational use of dental implants (DI) with direct prosthetics (DP) on installed implants at partial adentia is a modern and quick answer to this question. But still there is a number of unresolved issues in the method of direct prosthetics on DI. The most relevant of these is how to use modern CAD/CAE/CAM technologies to personalize the eruption profile of natural teeth while maintaining the height of periimplantative bone tissue (BT) and the volume of surrounding soft tissues. Purpouse: to improve the quality of stomatological treatment of patients at the stages of dental implantation by applying an improved algorithm of direct prosthetics on dental implants on the basis of scientific justification of rational use of personalized prosthetic constructions and prosthetic elements, as well as pharmacological support of such interventions. Materials and methods of research. The clinical study included 80 patients – 63 patients were included in the main cohort (had dentition defects and/or required tooth extraction) who were randomized into three groups (I–III), according to the applied treatment; 17 patients were included in the additional cohort (group IV – without dentition defects) who's clinical and laboratory parameters were within the physiological norm. According to the above distribution of patients of the main cohort by study groups (groups I-III), each patient received the following treatment measures according to the study plan. Patients in group I (21 patients) used an improved direct prosthetics (DP) algorithm on DI with screw fixation of prosthetic structures from the level of the implant platform, and patients in group II (21 patients) – from the level of mesostructure of multi-unit abutment with the manufacture of individualized hybrid and/or crowns using CAD/CAE/CAMtechnologies. Prevention of inflammation and pain in patients of groups I–II was carried out by prescribing a complex of pharmacological support, which contained – the drug nimesulide, a complex drug bromelain, trypsin, in combination with drug rutoside threehydrate, and the drug trometamol dexketoprofen. Patients in group III (21 patients) used the conventional protocol of DP on DI with screw fixation of prosthetic structures from the level of the DI platform with the use of standard prosthetic elements and structures of artificial crowns made by traditional laboratory methods, while preventing inflammation and pain in patients of this group was carried out by prescribing a complex of pharmacological support, contained of the drug meloxicam, a complex drug of bromelain, trypsin, in combination with the drugrutoside threehydrate, as well as the drug ibuprofen. Clinical, functional and radiological studies, followed by statistical analysis of the results were provided for the patients of groups I–IV. Results. Prescription of the proposed pharmacological support complex at the stage of direct prosthetics in dental patients of groups I and II allowed to prevent pro-inflammatory resorption of BT due to surgical trauma of bone and soft tissues in the area of dental implantation, minimize loss of marginal BT around DI. Patients of groups I and II achieved a significant (p < 0.05, compared with group III) increase in the coefficient of stability of the implant (CSI) starting from the 20th day (group I – 65.37±1.12 units and group II – 64.93±0.75 units) in contrast to the delayed increase of this coefficient in group III (63.18±0.72 units), in which this indicator began to increase only from the 30th day. As a result, the loss of the height of the marginal BT after 12 months (1.11±0.03 mm) in group III was significantly (p < 0.05) higher than in groups I and II. Structural features of standard abutments, and the lack of ability to reproduce the anatomical features of the natural eruption profile of prosthetic structures made manually in traditional way contributed to a significant increase in the rate of loss of marginal BT (1.20±0.04 mm) in 24 months in patients of group III in contrast to patients of groups I and II. Instead, the minimal loss of marginal BT height throughout the study period was observed in group II which used an improved algorithm of DP on DI with screw fixation of prosthetic structures from the mesostructure of multi-unit abutment with the manufacture of individualized hybrid crowns with the help of CAD/CAE/CAM-technologies. The use of multi-unit abutments allowed to seal the access to the DI shaft and to carry out all subsequent stages of prosthetics at a level higher than the DI shaft. In particular, in group II of the study absence of infection with oral fluid in the DI shaft during the stages of prosthetics, minimization of trauma to the marginal bone, periosteum and soft tissues around the DI during impression obtaining, fixation of temporary and permanent structures of dental prostheses, as well as the author's algorithm of reproduction of a natural profile of eruption allowed to maintain a significantly higher (p < 0.05) volume of BT around the DI after 12 and 24 months in comparison with group I where titanium platforms and personalized constructions of abutments and profiles of eruption of dental prostheses were used and group III, where standard abutments from the level of DI shaft and traditional constructions of dental prostheses were used. The results of remote clinical trials have demonstrated the high efficiency of the proposed complex of treatment measures and the rationality of its components according to the algorithm in patients of groups I and II compared to traditional approaches in patients of group III. The loss of periimplantative soft tissue height after 12 and 24 months of DI was significantly lower (p < 0.05) in patients of groups I and II, compared with group III. In group II after 12 and 24 months the loss of soft tissues around DI was significantly lower (p < 0.05) compared with group I. Conclusions. Prescription of the proposed pharmacological support complex at the stage of dental implantation and direct prosthetics on DI, contained of the drug nimesulide, complex drug bromelain, trypsin in combination with the drug rutoside threehydrate and trometamol allowed to prevent inflammation-induced resorption of BT in areas of surgical trauma of bone and soft tissues, helped to minimize the loss of marginal BT height around the DI. In patients of groups I and II, that received the proposed complex of pharmacological support, the loss of BT in the first 6 months after the intervention was significantly smaller (p < 0,05) (group I – 0,15 ± 0,04 mm, group II 0,10 ± 0,02 mm), and KSI credibly (p < ) bigger in contrast to patients of group III (loss of BT 0.66 ± 0.03 mm, KSI 79.06 ± 0.54 units) in whom pharmacological support contained meloxicam and ibuprofen, the action of which was insufficient for full prevention of trauma and inflammation for induced local resorption of the marginal bones around the installed DI, and as a consequence of the predominance of BT resorption processes over its formation. According to the results of remote (after 12 and 24 months) clinical and radiological examinations in patients of groups I and II who used identical in composition to author's complex of pharmacological support and developed personalized protocol of direct prosthetics on DIfound significant differences in bone and soft tissue loss around DI between these groups. It is proved that the use of personalized protocol of direct prosthetics on dental implants from the level of mesostructures of multi-unit abutments in patients of group II prevented multiple injuries of the marginal bone, periosteum and mucous tunic around the DI during routine prosthetic manipulations. As a result, in group II were found significantly lower (p<0.05) rates of bone and soft tissue loss around DI after 12 and 24 months after dental implantation and direct prosthetics in comparison with group I. The proposed author's protocol of direct prosthetics on dental implants using modern CAD/CAE/CAM technologies allowed reproducing natural eruption profile in personalized way. When used in patients of group II from the level of multi-unit abutments after 24 months significantly better (p<0.05) results were obtained in maintaining the height of periimplantative bone tissue and the volume of surrounding soft tissues compared to traditional prosthetic methods used in patients of group III. Key words: direct prosthetics, dental implantation, personalized approach, CAD/CAE/CAM-technologies, multi-unit abutment.


We have experienced 33 cases of acromioclavicular dislocation during past 15 years.Good therapeutic results were not always obtained in those cases who received operative procedure.From the results described above, closed reduction using Spigelman's Harness were performed in 8 cases, and good reduction and fixation were obtained in 6 cases of them.


There is a printing error in Table 8 of Parthe & Gelato [Acta Cryst. (1984), A40, 169-183]. For PuBr3 the published space group was Ccmm, while that for the standardized data is Cmcm.


Self-compacting rubberized concrete (SCRC) is a high-performance concrete that can achieve compacting effect by self-gravity without vibration during pouring. Because of its excellent fluidity, homogeneity, and stability, the application of self-compacting concrete in engineering can improve work efficiency and reduce project cost. The effects of loading rate on the fracture behavior of self-compacting concrete were studied in this paper. Three-point bend (TPB) tests were carried out at five loading rates of 1, 0.1, 0.001, 0.0001, and 0.00001 mm/s. The dimensions of the specimens were 100  mm × 100 mm × 400 mm. A precast crack was set in the middle of the specimen with a notch-depth ratio of 0.4. The experimental results show that the peak load on the load-CMOD (crack mouth opening displacement) curve gradually increases with the increase of the loading rate. Although the fracture energy a presented greater dispersion under the loading rate of 1 mm/s, the overall changes were still rising with the increase of the loading rate. Besides studying the softening characteristics of the self-compacting concrete, the constitutive softening curve of the self-compacting concrete was obtained using the bilinear model. Finally, curved three-point bending beams were simulated by using the extended finite element method based on ABAQUS. The fracture process of the self-compacting concrete under different loading conditions was analyzed more intuitively. The simulation results were compared with the experimental results, and the same conclusions were obtained.


The last decades have seen a growing interest in the impact of action on perception and other concurrent cognitive processes. One particularly interesting example is that manual rotation actions facilitate mental rotations in the same direction. The present study extends this research in two fundamental ways. First, Experiment 1 demonstrates that not only manual rotations facilitate mental rotations but that mental rotations also facilitate subsequent manual rotations. Second, Experiments 2 and 3 targeted the mechanisms underlying this interplay. Here, manual steering wheel rotations produced salient visual effects, namely the rotation of either a plane or a horizon in an aviation display. The rotation direction of these visual effects either did or did not correspond to the direction of the manual rotation itself. These experiments clearly demonstrate an impact of sensory action effects: Mental rotations facilitate manual rotations with visual effects of the same direction (as the mental rotation), irrespective of the direction of the manual rotation. These findings highlight the importance of effect anticipation in action planning. As such they support the contentions of ideomotor theory and shed new light on the cognitive source of the interplay between visual imagery and motor control. Human beings are able to act in two fundamentally different ways: either overtly by generating motor output or covertly by performing mental operations. Although at first glance motor and mental actions appear to be distinct, there is in fact a rich interplay between them. For example, motor actions have an impact on perceptual and attentional processes that can be facilitatory (e. Influences of motor actions on mental processes become particularly apparent with commensurate tasks from both domains, such as the combination of manual and mental rotations. We first briefly review this research. We then introduce a theoretical framework— ideomotor theory—that accounts for such influences. This framework predicts that not only manual rotations affect mental rotations but, conversely, that mental rotations affect manual rotations as well. Moreover, it suggests that the sensory consequences of these actions rather than the manual actions themselves are critical for this impact. These predictions derived from ideomotor theory are tested in three experiments in an aviation setting. Taken together, this research demonstrates how the ideomotor mechanism of sensory anticipation in action control can explain reciprocal effects of action and perception, thereby bridging several seemingly separate disciplines, such as motor control, visual imagery, and human factors research. The process of mental rotation (i.e., imagining …


Sometimes better yields were reported from fields sown with flax variety mixtures than from those sown with of pure varieties. The variety Victory performed well in both farm and experimental plots. Tests were conducted at Fargo, North Dakota in 1947-49 to determine the relative yields of an early, a mid-season and a late flax variety when sown separately and in mixtures. The varieties selected were Sheyenne, Dakota, and B5128, all rust resistant. Date of sowing and climatic conditions greatly influence the
relative maturity of flax varieties.


The ODISSEI Portal will combine metadata from a wide variety of social science research data providers into a single interface, allow advanced semantic queries to support findability, and facilitate data access. In particular, the Portal will include metadata of (a) the microdata catalogue from Statistics Netherlands, and (b) survey datasets collected by ODISSEI member organizations in the Netherlands. Aligning the metadata from these sources is the primary challenge of this project. The project will ultimately develop a metadata ingestion pipeline to make sure that the Portal can be maintained and kept up to date. This pipeline will convert the metadata of the source surveys to the CESSDA Metadata Model (CMM) used in the portal. The ODISSEI Portal will extend and improve search functionality by using semantic queries which will enable broader probabilistic matching over an enriched knowledge graph representation of the metadata catalogue. This incorporates the context of specific terms which are crucial in social research. By using rich and extensible data structures developed within the linked data community, ODISSEI will develop the relatively flat metadata catalogue in use today into a highly interlinked and graph-based structure needed to conduct advanced semantic searches.


Earthquake is the most severe natural disaster threatening safety of pipelines,and the compression,distortion and cracks of pipelines will occur under seismic action.In recent years,earthquakes have occurred frequently and,with the construction of large long-distance natural gas pipelines and the use of large-diameter and high-pressure steel pipes,the research of the safety of pipelines under seismic action to guarantee the safe and reliable operation of pipelines is critical.At present,scholars have established many models on analyzing the damage patterns of pipelines under seismic action and lots of achievements on theoretical analysis,numerical simulation and experimental research have been made.Based on the description of progress both at home and abroad,this paper points out that the mechanical response of pipelines under gas-solid coupling,the safety of higher level steel pipelines under seismic action,the damage mechanism of pipelines under peculiar soil and various geological disasters,and the relevance between seismic hazard and pipeline damage should be further studied.


The present study was carried out at Krishi Vigyan Kendra, Rajsamand to know the yield gaps between improved package and practices (IP) under Front Line Demonstration (FLD) and farmer's practice (FP) of rapeseed-mustard crop. The study found, the yield of rapeseed-mustard in IP under irrigated conditions ranges from 15.89 to 18.64q/ha whereas in FP it ranges between 12.53 to 14.02q/ha. The per cent increase in yield with IP over FP was recorded in the range of 26.82 to 33.14. The extension gap and technological index were ranging between 3.36-4.64q/ha and 22.33-33.79 per cent, respectively. The trend of technology gap reflected the farmer's cooperation in carrying out demonstrations with encouraging results in subsequent years. The cost benefit ratio was 3.19 to 3.52 under demonstration, while it was 2.36 to 2.69 under control plots. By conducting front line demonstration of proven technologies, yield potential of rapeseed –mustard crop could be enhanced to a great extent with increase in the income level of the farming community.


Estimates of any given flux (momentum, heat, or moisture) that use the full set of diabatic profile relations applicable to the marine atmospheric surface layer require an accurate representation of flux coefficients, diabatic parameters, roughness lengths, and mean values for all meteorological quantities. Calculation of the momentum flux, for example, requires that the stratification function include both temperature and humidity effects and that the solution to the equation set be based on full set iteration. We find that over warm water, particularly during cases of low humidity, the momentum flux and stratification estimates are very sensitive to the reported relative humidity. Similarly, we find that the ERS 1 radar cross section, when treated as a function of the wind stress (or momentum flux), varies significantly with relative humidity, particularly when surface temperatures are warm. This study suggests that any calibration/validation campaign using remote-sensing observations, in particular the ERS 1 scatterometer, should utilize high-quality ground truth relative humidity measurements in addition to the traditional suite of high-quality wind and temperature gradient measurements.


Promoting innovations in a cost-effective and risk-adjusted regulatory framework is required to reach the climate targets. The paper provides a needed classification of innovation and shows a range of options to tackle hurdles in the German regulatory framework. Furthermore, the most adequate solution is derived, reflecting also successfully implemented regulatory approaches in other European countries.


Research has been conducted in order to critically evaluate and examine the level of employees' satisfaction among the employees of Tirumala Milk Products Private Limited. The purpose of this study is also to observe and analyze the factors which create job satisfaction especially among the hardworking employees, and to find out the reasons of dissatisfaction if any. The primary data for this study was compiled through questionnaire filled in on a one-to-one basis by 125 respondents from a representative sample of employees of Tirumala Milk Products Private Limited. The results have shown that working environment, compensation, growth opportunities and training & development are the most important significant factors which directly influences in affecting Job Satisfaction. According to a number of literatures studied, lack of job satisfaction is a serious issue in various organizations and job dissatisfaction has become a major obstacle in employees' productivity and organization's growth. There are numbers of factors which can create job dissatisfaction among employees but in this study the very critical factors are discussed upon which the Tirumala Milk Products Private Limited management should really work on the job satisfaction of its employees.


: We argue that standard tools of holography can be used to describe fully non-perturbative microscopic models of cosmology in which a period of accelerated expansion may result from the positive potential energy of time-dependent scalar fields evolving towards a region with negative potential. In these models, the fundamental cosmological constant is negative, and the universe eventually recollapses in a time-reversal symmetric way. The microscopic description naturally selects a special state for the cosmology. In this framework, physics in the cosmological spacetime is dual to the vacuum physics in a static planar asymptotically AdS Lorentzian wormhole spacetime, in the sense that the background spacetimes and observables are related by analytic continuation. The dual spacetime is weakly curved everywhere, so any cosmological observables can be computed in the dual picture via effective field theory without detailed knowledge of the UV completion or the physics near the big bang. In particular, while inflation may explain the origin of perturbations in the cosmology picture, the perturbations can be deduced from the dual picture without any knowledge of the inflationary potential.


Malaysian Government wanted to replace the Sales and Service Tax with Goods and Service Tax (GST).The first reading of the GST Bill was tabled in Parliament in December 2009 but the second reading planned in March 2010 was postponed till now.The government would only introduce once everyone understand and familiar with the tax.This study is aimed to explore the perception of tax agents towards the proposed GST.This study is a cross sectional where data was collected only once.Four (4) variables were used to measure the GST perceptions.Questionnaire was used to capture the data.A survey was carried out to acquire the data from 1,200 tax agent throughout Malaysia.Only 157 responded where two questionnaires were unusable giving a 13% (155) response rate.Data were analyzed using descriptive statistics on the demographic variables and four constructs.Test of reliability and validity were also done on the four variables.The result indicated that tax agents in Malaysia have good perception towards the Government intention to introduce GST.All the items in the four constructs except one have mean score of above 3.00. Both the cronbach alpha value and KMO value have more than 0.800 for all the four constructs.Respondents also indicated that the most prominent probable area of difficulties in GST was the understanding or knowledge of GST.The findings suggest that the attitude, awareness, understanding and preparedness of tax agents are positive towards the implementation of GST in Malaysia.This study provides important and valuable inputs for the Government to implement strategic plan to enhance the level of understanding to taxpayers so that GST can be introduced without obstacles.


Generic classifications are indispensable to mass or commercial culture at the same time that their practice in postmodernity grows more and more complex or hybrid. Is The Wire a police procedural, for example? No doubt, but it is also a version of the organized crime story. The majority of its actors and characters are black, which nonetheless does not exactly make it a black film (a film for black audiences). There is a political drama going on here, as well, but its nature as local politics reminds us that it is also very much a local series, one framed in Baltimore and very much about Baltimore (something not always to the liking of Baltimore's elites). It is, however, also the case that most detective or crime literature today (as well as its filmic offshoots or inspirations) is local and based on the con sumption of a specific landscape (whether a foreign country—Swedish detective stories, Italian ones, even Chinese detective stories—or re gional—Montana, Louisiana, Los Angeles, Toronto, etc.). The broadest categories would then be that of the thriller or that of the action film (al though there are few chase scenes, no cliff-hangers, few-enough mass ac tion or carnage scenes). Each of the five years of the TV series is a unit in terms of plot and theme; and there are at least a hundred characters deployed in each sea son, many of whom carry their own independent plotlines. It may be ar gued that there is a single major protagonist, the Irish American detective Jimmy McNulty (Dominic West), even though his status fluctuates over the five years of the series and is often eclipsed by other characters. This is to say that a work of this kind challenges and problematizes the distinc tion between protagonists and "secondary characters" (or stars and "char acter actors"), in ways most often described, I guess, as "epic" (War and Peace, Gone with the Wind)—a characterization that does not help to un derscore what may be a historical development in the evolution of this kind of plot (see Alexander Woloch on secondary characters). The episodes in each series are not separate and freestanding as they were in Homicide (screenwriter/producer David Simon's previous series,


Structures of interest to hydroacoustic research frequently have spatially varying properties that cause the field variable to be statistically nonhomogeneous. Two wavenumber spectra of one‐dimensional nonhomogeneous fields have been defined [W. A. Strawderman, J. Acoust. Soc. Am. Suppl. 1 80, S15 (1986)], but there exists little experience in interpreting these spectra. This paper presents a first look at the two wavenumber spectra of various theoretical and measured examples of nonhomogeneous fields. The examples are chosen to form a progression of two wavenumber spectra from simple canonical forms of exponentially damped traveling waves to more complex measured nonhomogeneous fields on axisymmetric periodic structures. The desired two wavenumber spectra are obtained from calculated or measured cross‐specral density matrices by use of an efficient algorithm. A comparison of the spectra of both the canonical and measured fields displays a common structure observed in both. One and two wavenumber spectra ...


Obesity is a serious health problem in the United States.Although laparoscopic surgical procedures are effective in achieving weight loss and improving obesity-related co-morbidities,they are not without their limitations and consequently there is a growing demand for less invasive approaches.Transoral techniques,as both primary and revisional procedures,are promising in this regard as they may provide a safer and more cost-effective means of achieving meaningful weight loss.The aim of this paper is to review the currently available transoral approaches to weight loss,with a particular focus on those applied in human trials.


International experience shows that the payment reform have taken a pre-pay system as its target.The payment is a multiple mixed method with bundled services,and its reform is a gradual transition,and needs corresponding accessory institutions to make a balance among the multiple goals.In China,the core of further payment reform is to carry out different payment methods with prospective bundled services.No one or multiple uniform payment methods could be importunely used because the conditions of regions in China vary remarkably.It is necessary to make different criteria in the state level,providing selection of different payment methods by defining beneficiaries,service package,and payment standards.It is recommended that local authorities could choose the payment system according to their own circumstances.This paper describes the concept,evolvement,incentives of provider payment system,level of risk and its relationship with the supervision of medical services.


This paper investigates the multi‐criteria decision function in which the information available is just ordinal information on preferences and importance. A procedure is developed to combine the individual objective orderings to form an overall ordering based upon importances of each of the objectives. The theory of fuzzy sets is used as a framework in this paper.


In the article the comparative analysis of operation of the threecoordinate spherical sensor of intensity in electric fields of the point source, a conductive lines and electric dipole is spent. The optimum structural dimensions of sensitive electrodes allowing to provide the set error of measurement is obtained.


In 2022, the gun suicide rate among Black teens surpassed its rate among white teens for first time on record, according to newly released provisional data from the Centers for Disease Control and Prevention (CDC). Additionally, the nation's overall gun suicide rate increased 1.6%, reaching an all‐time high.


Quantum Bernoulli noises are the family of annihilation and creation operators acting on Bernoulli functionals, which satisfy a canonical anti-commutation relation (CAR) in equal-time. In this paper, we consider a quantum Markov semigroup constructed from quantum Bernoulli noises. Among others, we show that the semigroup has infinitely many faithful invariant states that are diagonal, and satisfies the quantum detailed balance condition.


The paper describes how military display users can benefit from emerging commercial market trends toward wideformat and high-resolution displays. This emerging display format offers several human factors benefits and more information along with high-definition sensor compatibility. The current commercial market trend highlights the growth of wide formats, which may affect the future availability of standard format COTS displays. The vetronics display that is being developed for the FCS family of combat vehicles is an example of a COTS wide-format, high-resolution display that is ruggedized for the next generation of soldiers.


An optical disk system which uses a high numerical aperture (NA) objective lens is effective for achieving high recording density. However, in such a system, it is necessary to detect and compensate for the radial tilt of the disk, because the coma aberration which deteriorates the read/write characteristics increases and the radial tilt margin becomes narrower. For this purpose, a radial tilt detection method for DVD-RAM disks using the CAPA (Complementary Allocated Pit Address) was reported. This paper proposes a new radial tilt detection method for rewritable optical disks using a 3-beam optical head. This method features high-sensitivity characteristics and is suitable for high-frequency servo operation, because the radial tilt signal is obtained from push-pull signals instead of header signals.


Abstract : This report covers visits to several of Turkey's leading technical institutions and provides a survey of some of their facilities and ongoing research in applied material science; primarily with minerals, ceramics, polymers, and elastic constants. The institutes visited included: Middle East Technical University (METU), Ankara; Turkish Scientific and Technical Development Agency (Tubitak), Ankara; Mining Research Institute Ankara (MTA); Tubitak Electronics and Electrical Research Institute, Ankara; Marmara Research Institute, Gebese; and Ankara Nuclear Research and Training Center (ANAEM). Keywords: Metallography; Ceramics; Material Science; Minerals; Polymers.


A sonar system for indicating the presence of sonic energy reflecting interfaces in the water in the path of a downgoing sonic pulse. The received reflection or echo is recorded on a moving record or web by means of a stylus that is traversed across the web as a linear function of time. The movement of the stylus triggers the transmitted pulse and the received signal is then amplified and controls a high voltage source which generates a series of pulses applied by the stylus as it moves across the record. Under certain operating conditions there is considerable noise generated in the water by the sonic pulse due to the presence of many reflecting surfaces from sediment, algae, plankton, etc. which sustains the return signal to the transducer. A disable system is provided which on command of the operator will disable the operation of the transmitter and receiver on alternate operating cycles to provide time for this noise to attenuate.


A brief treatment of parsimony and conceptualism, in the predemocratic era is presented followed by a discussion of the administrative justice clauses in both the interim and 1996 Constitutions showing that the constitutional era offered only partial solutions to the problems of parsimony and conceptualism. The Constitutional Court's principle of legality is dealt with and the teachings of this principle in South African administrative lawyers are considered.


This paper presents an intelligent radio wave propagation prediction model by using the 2-dimension aerial image which is taken from the actual area. An suburban area is used as examples. The prediction procedure is done in three steps. First, the image segmentation is employed to divide the area image into subgroups by using Maximum Likelihood algorithm. The second step uses the subgroup images from step 1 to determine the parameters for the fuzzy model that we use to classify the propagation areas. The final step is to plot the path loss contour on the image so the cellular cell site can be chosen. The research results show that the proposed segmentation provides an accuracy of 80-90% compared with the actual area. Therefore, cell site selection can be designed on the 2-dimension aerial map with the error less than 8 dB.


Purpose – The purpose of this paper is to report a pilot study that evaluated an innovative practice in a faith community context designed to help older people live well at the end of life and prepare for death. Design/methodology/approach – A simple audit of the intervention using a contemporaneous journal kept by the author, and a follow up questionnaire completed by participants. Findings – Rich findings on the process are reported. These indicate a high degree of engagement by participants, the establishment of a high degree of group intimacy and trust, a high level of articulation of wisdom, the emergence of significant anxiety in some isolated cases, and the use made of tea and cake to manage the transition between the existentially demanding nature of the discussions and normal life. The outcome indicated very high levels of appreciation and increased confidence in relation to issues of death and dying. Practical implications – The findings of the pilot have been used to inform training of clergy i...


Fluid coupling is one kind of hydrodynamic transmission machine using the kinetic energy of liquid.It's very important to research on the fluid coupling internal flow field.Because of the objective condition limit,the research on the fluid coupling flow field simulation based on the one-dimensional beam theory.But it's much far from real instance.This paper constructs the mathematical equations of fluid coupling internal turbulent flow with the k-e turbulent model,and does the whole three dimensional flow field simulation for JO127X type fluid coupling of 1.7% slip operation condition with star-CD.The simulation calculation torsion is in accord with the experimentation well.At present there are no literatures or reports about other unit or company doing the research on three dimensional flow field simulation of fluid couplings successfully at home and abroad.


List of Charts List of Tables Publisher's Note Preface Acknowledgements Why is Money a Problem? Autonomy and the German Traditions of Liberalism Constituting Autonomy: From the Reichsbank to the Bundesbank Exercising Autonomy: From the 'Miracle Years' to the End of Bretton Woods 1958-1972 Towards Dominance: Central Bank Politics 1973-1982 The Emperor's New Clothes: Monetarism, Monetary Accumulation and the Blindness of Power 1982-1990 The Final Chapter: Germany, EMU and the Bundesbank Concluding Remarks Bibliography Index


The purpose of this thesis is the seismic control and reinforcement of an existing school building with a concrete bearing body in accordance with the Intervention Regulation (ΚΑΝEΠE, 2nd revision 2017). The school building is located in Pefki, and it was built in 1986 and has been studied under the reinforced concrete regulation 1954 and the seismic design of 1959. The materials of the construction, according to the calculations and the drawings of the bearer body is B225 concrete and StIIIb steel.
According to statistics, Greece, in terms of seismicity, ranks first in the Mediterranean and Europe and sixth in the world. The safety of buildings and of construction in general is undoubtedly a key factor in protecting lives in the event of an earthquake. For this reason, the first anti-seismic regulation was drafted and entered into force in 1959 and this is the first time that horizontal seismic actions have been included in the static vector calculation and the areas are classified as seismic zones. The introduction of the Earthquake Regulation did not mean that the structures designed with it, in particular the reinforced concrete floors, had sufficient earthquake resistance. There is a large proportion of buildings built before 1959, and these require high priority earthquake upgrades in public buildings in the country. On the basis of the above, in 1997, OASP (Seismic Planning and Protection Organization) was commissioned to conduct pre-earthquake control on public buildings.
The introduction of anti-seismic regulations was an important step. However, there are many buildings older than three decades that were not built according to modern regulations even though they still host important public services and are a gathering place for many people, such as schools or hospitals. This need has led to the drafting of the Intervention Regulation (NEC) which is an attempt at a comprehensive and comprehensive regulation aiming at establishing criteria so as to assess the carrying capacity of existing structures and rules for anti-seismic enforcement. redesign, and any interventions, repairs or reinforcements. In 2012, (ΚΑΝEΠE) became mandatory for all building reinforcement and repair studies.
Due to the tightening of seismic regulations, the need for an immediate assessment of seismic vulnerability and the enhancement of important buildings such as schools, hospitals, etc. was created in the context of this effort. According to EAC 2000, our building is of major importance III.Our building, as mentioned, was built based on the 1959 earthquake-proof design and therefore requires immediate earthquake-proof shielding. The part of the building we are studying consists of rooms, toilets, corridors etc. It consists of three floors the total area is 1085.10 m2 and each floor is 361.70 m2. The diploma study was done with the help of the static program Scada Pro. The analysis used to evaluate the bearing masonry was Pushover analysis. When performing the pushover analysis (static inelastic analysis) the simulation is subjected to horizontal loads distributed in a manner proportional to the inertial forces of the earthquake, which increase monotonically until a structural element is no longer capable of carrying its vertical loads. By introducing parameters into the program given by the regulation and first performing a resilient analysis that will give us the indicators of failure of the construction, then performing the resilient analysis we obtain results for the linear curve and the targeted displacement. Interpreting the results of the program gives us the necessary reinforcement for beams and columns with either concrete mats or FRP mats.


Introduction We performed a single-center nonrandomized study on patients who underwent endovascular aneurysm repair using polymer-filled or other self-expanding endografts. Methods Consecutive patients with asymptomatic infrarenal abdominal aortic aneurysms who underwent endovascular repair were retrospectively reviewed. They were divided into a polymer-filled (n = 20) or self-expanding group (n = 42). Baseline characteristics, operative mortality and morbidity, and follow-up data were compared. Results Aneurysm diameter, neck and iliac morphologies did not differ between the two groups. Technical success was 100%. The 30-day mortality was 0% and 2.4% in the polymer-filled and self-expanding group, respectively. At a mean follow-up of 17 months, the changes in sac size were −2.1 mm and −5.1 mm (p = 0.144) at one year, and −3.5 mm and −7.7 mm (p = 0.287) at 2 years in the polymer-filled and self-expanding group, respectively. The polymer-filled group had 7 (35%) type II endoleaks, and the self-expanding group had 1 (2.4%) type Ia and 13 (31%) type II endoleaks. Neck diameter remained stable in the polymer-filled stent-grafts whereas there was progressive neck degeneration in the self-expanding group. The rates of reintervention and overall survival were similar in both groups. The presence of an endoleak was the only predictor of non-regression of the aneurysm (odds ratio = 17.00, 95% confidence interval: 4.46–64.88, p < 0.001). Conclusion Polymer-filled endografts had similar safety, effectiveness, and durability to other self-expanding endografts. The major advantage is the small iliofemoral access. They also have the potential long-term benefit of a more stable neck.


Objective: Inquire into the cause and way ofreoperation on the residual gallstones in biliary dusts andprobe into the measure of reducing reoperation broportion.Methods: Analyse the reoperation of 36 patients on theresidual gallstones in biliary dasts in our hospital these sixyears. Results: Found 3 cases of the complication operatinetreatment on the patient of no avail by nonoperative treatment.After operation, we followed up a case by regular visits themtwo months equally, there were three cases, complicationscovering 8.3%, others were good. Conclusion: The preventivekey of the residual gallstones in the biliary ducts lies in thethoroughness of the ferse operation. The rational way slouldbe choosen for reoperating.


The capitol of Hubei province in China, Wuhan, became the center of an outbreak of pneumonia of unknown cause in December 2019 [1]. This outbreak of pneumonia was the emergence of the novel coronav...


Biological characteristics and larval feeding rate of hoverfly Eupeodes corollae Fabricus were determined on Aphis pomi De Geer at laboratory conditions. The experiments were carried out in growth chamber at 25±2 oC, RH 55-65% and a photoperiods of 16: 8 (L: D) h. The incubation periods of eggs, larval, pupal and developmental time of E. corollae were determined as 3.80, 12.60, 8.00 and 25.40 days, respectively. Adult longevity considerably increased (9.60 days) when fed with honey solution but in non-feeding situation, it lasted for only 3.00 days. There were significant differences (P<0.1) observed in daily and total feeding rate among the first, second and third instar larvae. Each larva of E. corollae fed on 392.20 aphids during larval period and revealed a high potential for feeding on A. pomi. The third instar larvae played an important role in feeding rate, such that 66.09% of total larval feeding was due to this instar. Per capita daily feeding rate of first, second and third instar larvae amounted to 6.68, 27.85 and 59.27, respectively. Because of considerable reproduction as well as feeding rate, hoverfly E. corollae can be employed in biological control, and in integrated management programs of different aphid species, specially A. pomi.


In order to evaluate the maximum available wind power capacity more accurately, a comprehensive evaluation method based on peak load regulation capability, static security and transient stability is proposed. With the help of stochastic production simulation technology, the wind power capacity absorbed by the power grid under the constraint of traditional peak load regulation capacity is modified, the combined capacity of each wind power access point is globally optimized by enumeration method, and the transient stability of the system is verified by setting large disturbance conditions, and finally the maximum wind power capacity that can be absorbed by the regional power grid is obtained.


Basic knowledge about the spread of human immunodeficiency virus (HIV) and safe sexual practices has a critical impact on prevention of the acquired immunodeficiency syndrome (AIDS) and other associated STDIs. The problem among students at higher education institutions (HEIs) is that they are a high risk group for contracting HIV/AIDS and STIs due to uninformed decisions that they make. This study aimed to explore the knowledge and attitudes of higher education students towards HIV/AIDS, sexual transmitted infections (STIs) as related to their sexually risky behaviour. This literature review revealed that most students engage in unprotected sex and that some students fear taking an HIV test. Since young people are the future leaders, there is need to educate them about the consequences of unprotected sex. Our communities need to stand together and educate the young people about the dangers of having multiple partners and unprotected sex. Many of students have substantial knowledge about and positive attitudes towards the use of condoms in preventing STIs, HIV infection and even pregnancy. There is enough evidence that alcohol abuse significantly contribute to inconsistency in condom use by students. DOI: 10.5901/mjss.2014.v5n14p380


According to the characteristics of the manufacturing enterprise, the efficiency of the human resources development and utilization in the manufacturing enterprise was analyzed. The five input indexes and the five output indexes were identified. The human resources efficiency evaluation indexes system was established. The necessary data were collected. The data envelopment analysis model was used to evaluate the efficiency. The calculation results were analyzed. The rationalization suggestions were put forward for the manufacturing enterprise. Application of data envelopment analysis in the human resources development and utilization is significant for the management of the manufacturing enterprise. The data envelopment analysis model establishment process and the result analysis were introduced.


Neutron diffraction with isotope substitution of nitrogen, chlorine and hydrogen nuclei is used to investigate the hydration region of both ions and the possibility of ion pairing in aqueous solutions of tetramethylammonium chloride (TMACl) at 0·5 m, 1·0 m and approximately 2·0 m concentration. The use of a maximum-entropy method to calculate the radial distribution functions is discussed. The H-H correlation function for the water in the 1·0 m solution is measured and compared with that for pure water. The nitrogen-substitution results are also compared with a hard-sphere model calculation. The results show that the TMA hydration is apolar rather than ionic, and is consistent with a disordered water-cage structure, while the water in the hydration sphere does not appear to be more ordered than in bulk water. There is no significant change in the hydration structure measured at the different concentrations, although at the highest concentration there may be evidence of the close approach of the anion and ...


This chapter investigates the relationships between communication styles, social networks, and learning in a Computer-Supported Collaborative Learning (CSCL) community. Using Social Network Analysis (SNA) and longitudinal survey data, the authors analyzed how 31 distributed learners developed collaborative learning social networks, when they had work together on the design of aerospace systems using online collaboration tools. The results showed that both learner's personality characteristics (communication styles) and structural factors (a pre-existing friendship network) significantly affected the way the learners developed collaborative learning social networks. More specifically, learners who possessed high Willingness to Communicate (WTC) or occupied initially peripheral network positions were more likely to explore new network linkages in a distributed learning environment. The authors propose that the addition of personality theory (operationalized here as communication styles) to structural analysis (SNA) contributes to an enhanced picture of how distributed learners build their social and intellectual capital in the context of CSCL.


Maternal metabolic changes occur during pregnancy to provide the fetus with a continuous energy supply. These changes appear directed toward 1) storing maternal fat during early pregnancy that can be used by the mother during late pregnancy, when there is an increased fetal demand for energy, and 2) direct demands by the fetus on maternal glucose to meet immediate needs. Exercise also causes an increased demand for energy and increases the uptake of blood glucose by exercising muscle. The increased glycemic requirement of exercise plus the fetal demands on maternal glucose has the potential to result in maternal hypoglycemia and a possible decrease in glucose availability to the fetus. In addition, protein needs increase during pregnancy because of the amino acids necessary for the synthesis of developing maternal and fetal tissues. If exercise increases the use of protein as a substrate, then the availability of amino acids for maternal tissues and fetal growth may be compromised. Energy metabolism and substrate utilization during exercise has received limited attention. Any discussion on exercise substrate utilization during pregnancy is complicated by several factors, including exercise intensity and duration, type of exercise, diet, stage of pregnancy, training status, and hormonal responses. This manuscript will briefly review 1) the normal metabolic responses to exercise, focusing on substrate use, 2) the influence of pregnancy on substrate (macronutrient) utilization at rest, 3) the acute and prolonged effects of exercise on substrate utilization, and 4) possible hormonal mechanisms related to exercise metabolism in pregnant women.


A 63-year-old woman was referred for catheter ablation of atrial fibrillation (AF). Two weeks before the ablation procedure, contrast-enhanced cardiac imaging was performed with a 16-slice spiral computed tomography (CT) scanner, and the planar CT images were converted to a 3D surface reconstruction of the left atrium (LA), left atrial appendage (LAA), and pulmonary veins (PVs) (Figure 1). During the electrophysiology study, a transseptal puncture was performed to enter the LA to allow mapping of the LA, LAA, and PVs with an electroanatomic mapping system (Biosense-Webster, Inc). A custom, image-guided therapy workstation was developed capable of (1) importing the 3D CT surface reconstruction, as well as electroanatomic mapping information (including real-time …


Upadacitinib (UPA) has demonstrated efficacy in randomized controlled trials1-3; however, few data are available from patients with rheumatoid arthritis (RA) who have been treated with UPA in real-world clinical practice.Describe the characteristics and 6-month outcomes in patients with RA initiating UPA in a real-world setting.We identified adults with RA enrolled in the Corrona RA Registry through October 31, 2020 who initiated UPA during or after August 2019 and had a follow-up visit 6 (±3) months after initiation of UPA. Descriptive statistics were used to summarize characteristics in all patients initiating UPA who had a 6-month follow-up visit. Outcomes (CDAI, modified HAQ-DI, pain, and fatigue) were described at the 6-month visit for all UPA initiators regardless of UPA use at 6 months and for the subset of patients who continued UPA through the 6-month visit. Patients who discontinued UPA before the 6-month visit were considered non-responders for dichotomous variables and were assigned the value at the time of discontinuation for continuous variables. Mean change from baseline in continuous variables was analyzed with one-sample t tests or one-sample Wilcoxon rank sum tests. Minimum clinically important difference (MCID) in HAQ-DI is defined as an improvement of 0.22 units or more. MCID in CDAI is an improvement of at least 2, 7, and 13 units for patients in low, moderate and severe disease at initiation, respectively. MCID for 100-point VAS is an improvement of ≥10 points. Percentages of patients achieving MCID thresholds were calculated.We identified 181 patients who initiated UPA and had a 6-month follow-up visit. Mean±SD age was 58.6±12.1 years, 81% were female. Patients had RA for a mean of 11.5±9.8 years. At UPA initiation, 45% of patients were on monotherapy. Prior use of one or more TNFi and JAKi was 79% and 52%, respectively. Seventy-two percent of patients (n=130) initiated UPA as the third or higher line of therapy. Mean CDAI was 18.7±11.6 and mean HAQ-DI was 1.1±0.8 at initiation. Based on CDAI (n=155), 29%, 52%, and 15% of patients had high, moderate, and low disease activity, respectively; 4.5% were in remission at initiation. At 6 months (n=158), 22%, 39%, and 28% had high, moderate, and low disease activity, respectively; 11% were in remission. Among 138 initiators with valid CDAI measures at initiation and 6 months, mean change in CDAI was –4.8±11.8, P<0.01. At 6 months, 46% (63/138) maintained and 39% (54/138) achieved improvement in any CDAI category. Improvements in other outcomes were significantly different from zero. Improvements >=MCID in CDAI, HAQ-DI, pain, and fatigue were achieved in 36–44% of UPA initiators. Improvements were similar, but larger in the subset of patients (n=122) who continued UPA through the 6-month visit (Table 1).Among patients in the Corrona RA Registry, UPA is frequently started in those who failed multiple previous therapies. UPA initiators responded to therapy in the first 6 months with improvements in several disease activity measures including CDAI and HAQ-DI, as well as patient-reported pain and fatigue.[1]Fleischmann R. Arthritis Rheumatol. 2019;71:1788–800.[2]Smolen JS. Lancet. 2019;393:2303–11.[3]Burmester GR. Lancet. 2018;382:2505–12.Outcomes at 6-month follow-upAll initiators(n=181)Subset remainingon UPA (n=122)nValueanValueaRemission (CDAI <2.8)15818 (11)10512 (11)Low (CDAI >=2.8 and <10)15844 (28)10538 (36)Moderate (CDAI >=10 and <22)15862 (39)10536 (34)High (CDAI >=22)15834 (22)10519 (18)Improvement in any CDAI category13854 (39)8940 (45)Maintenance of CDAI category13863 (46)10539 (44)Mean change in CDAI138–4.8±11.8*89–7.1±12.0* HAQ-DI154–0.1±0.5*101–0.2±0.5* Pain154–9.3±25.1*101–13.5±25.8* Fatigue153–7.6±27.3*100–12.5±27.5*MCID achievement in CDAI13857 (41)8943 (48) HAQ-DI15455 (36)10139 (39) Pain15468 (44)10153 (52) Fatigue15365 (42)10049 (49)aMean±SD or n (%).*P<0.01 for improvement significantly different from zero.This study was sponsored by Corrona, LLC. Corrona has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol Myers Squibb, Celgene, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Janssen, Merck, Momenta Pharmaceuticals, Novartis, Pfizer, Regeneron, Roche, Sun, UCB, and Valeant. The design, study conduct, and financial support for the study were provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the abstract. No honoraria or payments were made for authorship.Medical writing services were provided by Joann Hettasch of Fishawack Facilitate Ltd., part of Fishawack Health, and funded by AbbVie.Joel M Kremer Shareholder of: Corrona, Consultant of: AbbVie, Grant/research support from: AbbVie, Employee of: Corrona, Namita Tundia Shareholder of: AbbVie, Employee of: AbbVie, Robert McLean Employee of: Corrona, Taylor Blachley Employee of: Corrona, anna maniccia Shareholder of: AbbVie, Employee of: AbbVie, Dimitrios A Pappas Shareholder of: Corrona, Consultant of: AbbVie, Genentech, Novartis, Regeneron, and Roche Hellas, Employee of: Corrona


Uracil appears in DNA as a result of cytosine deamination and by incorporation from the dUTP pool. As potentially mutagenic and deleterious for cell regulation, uracil must be removed from DNA. The major pathway of its repair is initiated by uracil-DNA glycosylases (UNG), ubiquitously found enzymes that hydrolyze the N-glycosidic bond of deoxyuridine in DNA. This review describes the current understanding of the mechanism of uracil search and recognition by UNG. The structure of UNG proteins from several species has been solved, revealing a specific uracil-binding pocket located in a DNA-binding groove. DNA in the complex with UNG is highly distorted to allow the extrahelical recognition of uracil. Thermodynamic studies suggest that UNG binds with appreciable affinity to any DNA, mainly due to racil-DNA glycosylase


Data compressing, data coding, and communications in object-oriented multimedia applications like telepresence, computer-aided medical diagnosis, or telesurgery require an enormous computing power-in the order of trillions of operations per second (TeraOPS). Compared with conventional digital technology, cellular neural/nonlinear network (CNN)-based computing is capable of realizing these TeraOPS-range image processing tasks in a cost-effective implementation. To exploit the computing power of the CNN Universal Machine (CNN-UM), the CNN chipset architecture has been developed-a mixed-signal hardware platform for CNN-based image processing. One of the nonstandard components of the chipset is the cache memory of the analog array processor, the analog random access memory (ARAM). This paper reports on an ARAM chip that has been designed and fabricated in a 0.5-/spl mu/m CMOS technology. This chip consists of a fully addressable array of 32/spl times/256 analog memory registers and has a packing density of 637 analog-memory-cells/mm/sup 2/. Random and nondestructive access of the memory contents is available. Bottom-plate sampling techniques have been employed to eliminate harmonic distortion introduced by signal-dependent feedthrough. Signal coupling and interaction have been minimized by proper layout measures, including the use of protection rings and separate power supplies for the analog and the digital circuitry. This prototype features an equivalent resolution of up to 7 bits-measured by comparing the reconstructed waveform with the original input signal. Measured access times for writing/reading to/from the memory registers are of 200 ns. I/O rates via the l6-line-wide I/O bus exceed 10 Msamples/s. Storage time at room temperature is in the 80 to 100 ms range, without accuracy loss.


In response to continued elevated lead levels throughout the District of Columbia's distribution system, a collaboration was begun with the District of Columbia's Water & Sewer Authority (WASA) and Water Resources Division of U. S. Environmental Protection Agency's (USEPA) Office of Research and Development in late winter of 2004 to investigate the causes of the sudden increases in lead release. Lead levels had been slightly above the Action Level in 1991 through 1994. Although increases in pH and the addition of orthophosphate were investigated in pilot studies and desktop corrosion studies at that time, the 90 percentile lead levels dropped to below 0.012 mg/L throughout the midto late 1990s. This coincided with a program of increased flushing and considerably elevated free chlorine dosages (often as high as 4 mg/L) to provide improved control of biofilms and bacterial regrowth. However, by 2000, concern with the upcoming increases in stringency of disinfection byproduct regulations led to a decision to change to chloramination in an attempt to keep trihalomethane (THM) levels below the new standards. The change was made in November of 2000, and in the next Lead and Copper Rule (LCR) monitoring round, the 90 percentile lead level surprisingly was found to have jumped to over 0.07 mg/L. Subsequent LCR 90 percentile results have remained over 0.04 mg/L. The general history of lead levels is illustrated in Figure 1, keeping in mind that some sampling periods are represented by some different monitoring sites in the site pool, and there were also differences in the number of sampling sites required.


Purpose: An investigation was completed to determine how typical cooking procedures used in food preparation, such as baking and stir-frying, affect trans fats formation. Methods: Canola oil was used as the main fat ingredient. Zucchini cake and gingersnap cookies were baked at 180° C and 200° C, while stir-fried chicken was prepared at 200° C and 275° C. The lipids from the food were extracted following the Folch procedure, and analyzed for trans fatty acids according to ISO official method 15304. Results: Minimal changes were observed in the amount of trans fats during baking. Application of extreme temperatures during baking, which caused carbonization of the outer layer of products, yielded an insignificant increase in the amount of trans isomers. As with baking, stir-frying did not result in significant isomerization of the fatty acids, even when the oil was heated to 275° C and smoking heavily before the food was placed in it. Irrespective of the cooking procedure, linolenic acid was the most prone ...


THE CURRENT CRISIS OF BIODIVERSITY HAS HIT OLD-WORLD VULTURES ESPECIALLY HARD; populations that flourished in the mid-20th century over much of Asia and Africa are in some cases close to extinction (1). In Europe, however, vultures have been spared, and today the Mediterranean basin is home to the largest populations of the Western Palearctic (2). The availability of carcasses around stock farms became a decisive factor in the survival and expansion of vulture populations in southern Europe (3). The outbreak of bovine spongiform encephalopathy (BSE) in 2001 led to the passing of sanitary legislation (Regulation CE 1774/2002) that greatly restricted the use of animal byproducts not intended for human consumption. All carcasses of domestic animals had to be collected from farms and transformed or destroyed in authorized plants, contradicting member states' obligations and efforts to conserve scavenger species (4). The effects of this policy include a halt in population growth, a decrease in breeding success, and an apparent increase in mortality of young age classes (2). Conservation concerns determined the appearance of a number of European dispositions (2003/322/CE 2005/ 830/CE) regulating the use of animal byproducts as food for necrophagous birds. Although the aim of these dispositions is to guarantee food supplies, in practice the spatial distribution of feeding stations has become almost totally predictable and habitat quality has been modified artificially as a result. The repercussions of these changes on individuals, populations, and communities of avian scavengers are undoubtedly significant (2, 5–7). Partial solutions to this problem are being found, albeit slowly. In 2009, the European Union began discussing a Spanish proposal for a revised regulation of the use of animal byproducts not intended for human consumption. In April 2009, amendments were approved by the European Parliament obliging the European Commission to regulate exceptions that will guarantee the supply of carcasses and thus satisfy the requirements of avian scavenger populations. It is hoped that the definitive legislation will be in place by 2010 to 2011. The philosophy of this new policy should allow member states a greater flexibility in carrion provisioning. Taking into account sanitary guarantees, it seems clear that encouraging fallen stock to be left in situ is the most ecologically harmonious, inexpensive, and efficient management method for the conservation of scavengers. Fortunately, current knowledge of scavenger ecology is increasing rapidly and so, more than ever, collaboration between ecologists, veterinarians, farmers, and legislators is both possible and desirable. JOSÉ A. DONÁZAR,1 ANTONI MARGALIDA,2* MARTINA CARRETE,1 JOSÉ A. SÁNCHEZ-ZAPATA3 Department of Conservation Biology, Estación Biológica de Doñana, CSIC, 41092 Sevilla, Spain. 2 Bearded Vulture Study and Protection Group, El Pont de Suert, 25520 Lleida, Spain. Department of Applied Biology, University Miguel Hernández, 33012 Orihuela, Alicante, Spain.


Mass transport is performance-defining across energy storage devices. An example of this limitation is evident in energy dense lithium-ion batteries (LIBs), which develop concentration gradients from insufficient transport of lithium-ions (Li-ions) when operated at high current rates. This results in lowered capacity and energy due to underutilized active material and increased overpotential. The movement of Li-ions, or lack thereof is the root cause of the trade-off that exists between energy and power density in LIBs. To alleviate societal demur towards the full adoption of electric vehicles, range anxiety and slow charging are predominant challenges that industry and academia are rushing to overcome. These goals may require reimagined processing methods to move beyond planar electrodes with disorganized and heterogeneous porosity to create architectures that are dense in active material and contain tailored porosity. To maximize the geometric component of diffusion and species flux, porous low-tortuosity channels are a rational design choice, as they act as mass-transport highways for much needed through-plane Li-ion transport.
 One such innovative process is hybrid inorganic phase inversion (HIPI), a manufacturing method that is scalable, material-agnostic and results in low-tortuosity free-standing and monolithic architectures with tunable material-to-pore ratios. The HIPI process can enable electrodes with adjustable thicknesses of 100s of µm and relevant micro-architectural feature sizes between 5-40 µm, tailored by tuning the gelation temperature and nucleation density of the inorganic suspension during the nonequilibrium HIPI process. Importantly, the use of a soft organogel casting support results in the unhindered accessibility of the low-tortuosity pores present in the HIPI architectures.
 HIPI-architected anode and cathode electrodes exhibit electrochemical and architectural stability over a 1000 cycles in a full-cell battery. Further, mass-transport constraints appear at high current densities, and we identify the lithiation step as rate-performance limiting, a result of insufficient Li-ion supply and concentration polarization. Thus, for energy and power dense LIBs the answer is not simply mass-transport highways as unoptimized low-tortuosity channels, rather in-plane Li-ion demands must be tethered to the through-plane transport. Our results demonstrate the need for and feasibility of tailored electrode architectures where dimensional ratios between low-tortuosity channels, the charge-storing matrix, and electrode thickness are tunable, to both understand multi-scale structure-performance relationships and meet coupled power and energy-storage requirements.
 References:
 [1] Resing, A. B., et. al., Adv. Mater.

 2022

 [10.1002/adma.202209694]

 Figure 1


The article focuses on the concept of «professional pedagogic intercultural competence» of a foreign language teacher. The author highlights the key components of the content of intercultural professional training of future teachers.


Stability of the banking system is underpinned through an effective bank monitoring mechanism since the sector is resilient to a range of single and combined shocks. Banks financial stability in the Gulf Cooperation Council (GCC) countries was empirically assessed by using z-score as a dependent variable. A group of macro and microeconomic independent variables were selected to measure their effects on banks stability. All banks in this region that are considered Conventional or Islamic banks were selected. The targeted period was 2003-2010 to cover pre- and post- financial crisis. It was found that there is no evidence that there is a significant difference between the financial stability of Conventional and Islamic banks for the periods 2003-2010, 2003-2007, and 2008-2010. However, Conventional banks tend to be financially stronger than Islamic banks for the pre- financial crisis.


Kevorkian, Martin. Writing beyond Prophecy: Emerson, Hawthorne, and Melville after the American Renaissance. Baton Rouge: Louisiana State University Press, 2013. 259 pp. cloth, $45.00. kindle, $19.25. Martin Kevorkian's Writing beyond Prophecy largely eschews the contextual, post-canonical approaches that have re-shaped American literary study over the past two decades. Rather, as Kevorkian writes in his introductory chapter, his goal is "to examine these authors' relation to the practice of worship" (3). In staking out the necessity and significance of such a task, Kevorkian ends his introduction with the following declaration: "Much scholarship seems to be written as if, once Emerson turned his back on the church, literary America breathed a sigh of relief and never looked back. Writing beyond Prophecy, attending to Emersonian inspiration and its aftermath, suggests otherwise" (19). The three extended and deeply interrelated chapters that follow build on the foundational claim that Emerson, Hawthorne, and Melville all wrote works late in their careers that depict what he calls "the troubled figure of the minister" (3). As he works his way through Emerson's "Worship" (an essay from The Conduct of Life [1860]), Hawthorne's The Elixir of Life manuscript (begun in 1861 and left unfinished upon his death in 1864), and Melville's Clarel (published in 1876), Kevorkian argues that all three texts "enact and represent a shared set of concerns about ministry and vocation" (3). While the traditional critical take on these writers is that their careers were shaped by, and greatly contributed to, the secularization of American culture during the 1840s and 50s, Kevorkian suggests that each eventually reconsidered his earlier rejection or evasion of ministerial models of religious practice, ultimately arriving at a retrospective appreciation for "the need for such a role model" (13). The chapter on Emerson traces the one-time Unitarian's renunciation of the ministry, his "silence" on matters of religion and divinity in his writings and lectures throughout the 1840s and 50s, and finally the emergence of the preacher figure as an important rhetorical touchstone in The Conduct of Life, especially in "Worship." What stands out in that essay, Kevorkian argues, "is not another assurance of the capacity for self-authorization, but the idea that one would seek guidance from a preacher, that one would no longer refuse a good model" (72). In building his case that the author of "Self-Reliance" and "The American Scholar" came to appreciate the more social dimensions of selfhood, Kevorkian concludes that "[a]t some point, the experiment of turning to persons has become an acceptable one for the endless seeker" (75). Those primarily interested in what Writing beyond Prophecy has to say about Hawthorne might find that he functions as something of a place-holder in Kevorkian's argument, allowing him to link Emerson's reevaluation of his own secular individualism with what might be called the aspirational spiritualism of Melville's Clarel--in which "victory is not an achieved certainty, but rather the prospect pursued, an object of spiritual desire that lies beyond the horizon of human knowledge" (148). The Hawthorne chapter opens with Kevorkian's slyly noting, "Hawthorne's career as a preacher was somewhat shorter than Emerson's; understandably, the collected sermons of Nathaniel Hawthorne have received considerably less critical attention" (81). Such a transition from Emerson playfully acknowledges the surprising nature of his juxtaposition of these two very different writers. In fact, the "career" Kevorkian is referring to here comprises one instance of preaching that Hawthorne describes among the "Consular Experiences" included in Our Old Home (1863). In this episode, Hawthorne writes of an American preacher travelling in Europe who vanishes, only to reappear at Hawthorne's office (during his tenure as U.S. Consul in Liverpool) looking disreputable and seemingly dissipated. …


Purpose: The nexus between Corporate Sustainability Practices (CSP) and Corporate Financial Performance (CFP) has over the years yielded a mix of positive, negative, and neutral associations across industries and territories. Considering the paradox of economic benefits against negative sustainability implications of manufacturing and consuming alcoholic beverages, the researchers examined the influence of CSP on the CFP of selected breweries in Nigeria. In two hypotheses, the proxies for CSP are Social-Infrastructural-Development Cost, Community-Education-and-Training Cost, and Community-Health-Related Cost, whereas the determinants for CFP are return on equity and prices of shares.
Methods: Adopting a causal-comparative research design, data were obtained from the annual financial reports of the companies and the Nigerian Stock Exchange factbooks. The multivariate regression analysis was deployed for estimating the results.
Results: The general models for testing hypotheses one and two indicated that corporate sustainability practices do not significantly influence either the return on equity or the market prices of the shares of breweries in Nigeria.
Implications: The researchers concluded that changes in the level of CSP were not enough for predicting variations in the CFP of breweries in Nigeria. It was, however, observed that awareness about CSP and the related value is still low among capital market investors and consumers in Nigeria. Hence, breweries are encouraged to be consistent with such practices as the associated benefit may be incremental.


The purpose of this paper is to analyse the signal dependency of the camera-based coaxial monitoring system QMMeltpool 3D (Concept Laser GmbH, Lichtenfels, Germany) for laser powder bed fusion (LPBF) under the variation of process parameters, position, direction and layer thickness to determine the capability of the system. Because such and similar monitoring systems are designed and presented for quality assurance in series production, it is important to present the dominant signal influences and limitations.,Hardware of the commercially available coaxial monitoring QMMeltpool 3D is used to investigate the thermal emission of the interaction zone during LPBF. The raw images of the camera are analysed by means of image processing to bypass the software of QMMeltpool 3D and to gain a high level of signal understanding. Laser power, scan speed, laser spot diameter and powder layer thickness were varied for single-melt tracks to determine the influence of a parameter variation on the measured sensory signals. The effects of the scan direction and position were also analysed in detail. The influence of surface roughness on the detected sensory signals was simulated by a machined substrate plate.,Parameter variations are confirmed to be detectable. Because of strong directional and positional dependencies of the melt-pool monitoring signal a calibration algorithm is necessary. A decreasing signal is detected for increasing layer thickness. Surface roughness is identified as a dominating factor with major influence on the melt-pool monitoring signal exceeding other process flaws.,This work was performed with the hardware of a commercially available QMMeltpool 3D system of an LPBF machine M2 of the company Concept Laser GmbH. The results are relevant for all melt-pool monitoring research activities connected to LPBF, as well as for end users and serial production.,Surface roughness has not yet been revealed as being one of the most important origins for signal deviations in coaxial melt-pool monitoring. To the best of the authors' knowledge, the direct comparison of influences because of parameters and environment has not been published to this extent. The detection, evaluation and remelting of surface roughness constitute a plausible workflow for closed-loop control in LPBF.


As treat each target equally,the traditional grey situation decision making method can't reflect the preference of the decision maker and the actual problem: A new method for weight solution in situation decision making is proposed.First,the deviation between a certain affair and the rest affairs is calculated by a single target.Similarly,the deviation matrix is formed by total targets.Secondly,the weight of each target is computed by means of entropy.The entropy weight can reflect the difference of each situation better.This method improves the theory of grey situation decision making and the example also shows its feasibility.


Remimazolam is a new benzodiazepine sedative and has the characteristic of causing minimal effects on circulation. This case indicates that it can be considered as an option for anesthesia management of patients with decreased cardiac function.


Exfoliated graphite/polyaniline (EG/PANI) composites were successfully prepared via in situ polymerization of aniline monomer in the presence of exfoliated graphite. The PANI precipitated into the interlayer space of the graphite flake significantly improving physiochemical properties of EG. The particle morphology and interaction of the EG and PANI was determined using the scanning electron microscopy (SEM). The SEM images clearly showed the formation of PANI and EG/PANI composite with PANI greatly covering the EG flake. The presence of polyaniline and its major functional groups were confirmed using Fourier Transform Infrared Spectroscopy (FTIR) between 3,500 – 3,000 cm and 1,500 500 cm. A 68 % change in BrunauerEmmett-Teller (BET) surface area was observed in the 0.35 g PANI/g EG after the in situ polymerization of the PANI. The effectiveness of the composite adsorbent on the removal of Cr (VI) from aqueous solutions was evaluated by evaluating the effects of parameters such as EG to PANI ratio and initial concentration. The optimum composite loading was found to be 0.35 g PANI/g EG and removed more than 99 % of Cr (VI) from an initial concentration of 100 ppm was removed at 20 g/L loading within 4 h. The Freundlich adsorption isotherm model best described the adsorption of Cr (VI) with a regression coefficient, r of 0.99 showing the heterogeneous adsorption at the surface of the composite. The maximum capacity of the composite was 38.20 mg/g.


Population growth, technological progress and changes in consumption patterns in recent years have led to an increase in the solid waste. On the other hand, limit energy resources and raw materials caused waste to be considered as a waste material and also recyclable at the high level of scientific and applied research. In solid waste management, waste burning is regarded as one of ways for eliminating waste. In this study, municipal waste in one of the districts of Tehran was taken into account for a case study. Also, in special systems which need special care of temperature such as the system for controlling the temperature of the furnace fuel of burnable solid waste in temperature 950°C. Fuel requirements for design were also calculated. At the end of the project, fluent software was used to confirm the findings obtained from the city incinerator furnace design.


France is considering introducing an innovative new additional tax on the tobacco industry, in an effort to reduce the number of deaths from tobacco related illnesses. It is estimated that there are 60 000 deaths a year in France from these illnesses.

The proposed new tax, which would raise money to be used in France and in the developing world, is inspired by Unitaid, the international facility to buy drugs for developing countries. Unitaid's main source of funding is a levy on airplane tickets.

France's …


The rapid technological development causes a cryptographic algorithms with the old system becomes weaker. it is also getting easier to be collapsed because of the limitation of protection. Another reason is the key used for encryption has not been encrypted anymore. This problem encourages so many cryptography researchers to create a new safer cryptosystem. This research devises a permutation box based on the block cipher algorithmic and also a symmetric key. It is made by comparing the 64 bit and 128 bit of block cipher based on the motion scheme of the retro direct gear. This research is also combining AES box substitution to show shannon significance principle to iterated cipher process. The result of this research will show the effect of permutation box (P-Box) using motion scheme of retro direct gear and AES S-box statistically. It has a weaker correlation value between the plaintext and the ciphertext. It also has avalanche effect grade which is more than 30% so it is very disordered


In the article the question of brand promotion of educational institutions and educational services in the Internet resources. We propose a method of using social networks to attract a wide audience of students.


To investigate the allelopathic suppression of pearl millet (Pennisetum americanum L.), sorghum (Sorghum bicolor L.), guar (Cyamopsis tetragonolobus L.) and maize (Zea mays L.) by Achyranthes aspera L., germination bioassays were carried out under laboratory conditions. Aqueous extracts of various plant parts with 5% (w/v) and of root with 1, 2, 3, 4 and 5% (w/v) (on dry weight bases) concentrations of A. aspera were supplied to tested seeds. Extracts of all plant parts caused significant reductions in germination percentage, germination index, mean germination time and seedling root length compared with distilled water treated control. Maximum germination inhibition was observed in case of A. aspera root extract which resulted in 0% germination in pearl millet, guar and maize; and significantly lowest (6.25%) germination in sorghum. Germination index, mean germination time and seedling root length of crops showed a differential response to whole plant, fruit, leaf and stem extracts. However, least phytotoxic action was imparted by A. aspera stem extract. The highest phytotoxic ability of A. aspera root extract is due to presence of vanillic acid, ferulic acid and p-coumaric acid at higher concentrations in it as detected through high-performance liquid chromatography (HPLC) analyses.


Abstract Polymeric composite materials of aviation application based on carbon, organic, glass fibers and epoxy binders were exposed for 10 years under warm humid climatic conditions of the city of Batumi on the Black Sea Coast. In the process of the exposure interlayer shear strength was measured, which was compared with other mechanical and physical characteristics measured in the center and surface layers of exposed plates. It has been shown that the surface of composites exposed to solar radiation is destroyed and disrupted to a greater extent than the inner layers. The gradient of mechanical properties across the thickness of a specimen can be significant. To illustrate the effect, a diffusion model of defects for polymeric composite materials was examined.


Breast cancer possess highest incidence among cancers in women worldwide. Current therapy of this disease is insufficient, especially in aggressive subtypes like triple-negative or luminal-B breast cancer. An important assumption for successful therapy of breast cancer is early detection and therefore there is a need for identification of new diagnostic and prognostic markers. High potential in this field indicate long non-coding RNAs (lncRNAs), which are frequently deregulated in tumors, where they act as oncogenes or as tumor suppressors. One of the studied oncogenic lncRNAs is MALAT-1, which is over-expressed also in breast cancer. The aim of the thesis was to determine the expression level of MALAT-1 in breast cancer cell lines, silence MALAT-1 in selected cell lines and monitor the effect of estrogen on the expression of MALAT-1. Consequently, MALAT-1 effects on proliferation, apoptosis, migration and clonogenicity were analyzed in vitro and potential synergistic functioning of MALAT -1 silencing and estradiol treatment was evaluated. The results of this work suggest that MALAT-1 is involved in the process of clonogenicity, which is seems to be further potentiated by estradiol. Involvement of MALAT-1 in proliferation, apoptosis and migration was not significant


We present in this paper an update on the design of BEaTriX (Beam Expander Testing X-ray facility), an X-ray apparatus to be realized at INAF/OAB and that will generate an expanded, uniform and parallel beam of soft X-rays. BEaTriX will be used to perform the functional tests of X-ray focusing modules of large X-ray optics such as those for the ATHENA X-ray observatory, using the Silicon Pore Optics (SPO) as a baseline technology, and Slumped Glass Optics (SGO) as a possible alternative. Performing the tests in X-rays provides the advantage of an in-situ, at-wavelength quality control of the optical modules produced in series by the industry, performing a selection of the modules with the best angular resolution, and, in the case of SPOs, there is also the interesting possibility to align the parabolic and the hyperbolic stacks directly under X-rays, to minimize the aberrations. However, a parallel beam with divergence below 2 arcsec is necessary in order to measure mirror elements that are expected to reach an angular resolution of about 4 arcsec, since the ATHENA requirement for the entire telescope is 5 arcsec. Such a low divergence over the typical aperture of modular optics would require an X-ray source to be located in a several kilometers long vacuum tube. In contrast, BEaTriX will be compact enough (5 m x 14 m) to be housed in a small laboratory, will produce an expanded X-ray beam 60 mm x 200 mm broad, characterized by a very low divergence (1.5 arcsec HEW), strong polarization, high uniformity, and X-ray energy selectable between 1.5 keV and 4.5 keV. In this work we describe the BEaTriX layout and show a performance simulation for the X-ray energy of 4.5 keV.


This paper proposes a Hybrid Random PWM(HRPWM) technique using a LF2407 DSP board in order to spread the power spectra of an induction motor. The proposed method is composed to the PRBS (Pseudo-Random Binary Sequence) with the Lead-Lag random bit and the random triangular carrier for the logical comparison. Also, a DSP generates the random number, the PRBS and the three-phase reference signal, a MAX038 chip operating as frequency modulator generates the random triangular carrier. For verification of the proposed method, the experiments were conducted with a three-phase adjustable speed a.c drives, and the results of simulations and experiments are presented.


Smart Home Energy Management (SHEM) systems allow to optimize the usage of resources in our houses while making them comfortable to humans. However, in the development of SHEM systems only limited attention has been put to the impact of the system performance on the Quality of Experience (QoE), considering the humans mostly as the final recipient of the service rather than the central component of the whole service. In this paper, we consider a SHEM system that, on the basis of pre-created user profiles, aims to reduce the electricity costs while preserving the QoE perceived by the user (evaluated in terms of perceived user annoyance due to the shift of the appliance's starting time). We focus on the identification of the user profile during the live sessions in the SHEM scenario and on the analysis of the impact of such task in the SHEM system performance. To evaluate the impact of profile selection, we conducted experiments in which 12 people were asked to provide their feedback each time the SHEM system proposed a modified starting time for an appliance with respect to the user's preferences. From experiments results it is found that the SHEM system needs on average just one feedback from the user to find the best user profile.


The Knowledge Provenance Management System, KProMS, can capture the complete provenance of the data, information, and knowledge of a structured activity by modeling the details of the associated data generation steps of that activity as workflows. Its unique workflow representation captures relationships between the processing steps, material and information flows, and data input and output. In this paper, we demonstrate the use of KProMS to manage and analyze the experimental data of an innovative system for manufacturing drug products using dropwise additive manufacturing. Dropwise additive manufacturing of pharmaceutical products (DAMPP) uses drop on demand printing technology for depositing various drug formulations onto edible substrates. DAMPP requires and generates a range of data types, including camera and IR images, spectra, and numerical parameter values, both of real-time and off-line natures, and thus provide a rich illustration of KProMS capabilities to serve as knowledge management framework.


In this paper��we propose a method which can morph a high free virtual viewpoint image keeping the epipolar geometry relations based on View Morphing technique. It is works just by the images coming from two cameras with same parameter without 3D reconstruction or camera calibration. Experiments confirm that the morphed view based on the two parallel view points by using this method can produce any satisfied image at any high free degree position in the space. P


The evolution of wireless access technologies and mobile devices, together with the constant demand for video services, has created new Human-Centric Multimedia Networking (HCMN) scenarios. However, HCMN poses several challenges for content creators and network providers to deliver multimedia data with an acceptable quality level based on the user experience. Moreover, human experience and context, as well as network information play an important role in adapting and optimizing video dissemination. In this paper, we discuss trends to provide video dissemination with Quality of Experience (QoE) support by integrating HCMN with cloud computing approaches. We identified five trends coming from such integration, namely Participatory Sensor Networks, Mobile Cloud Computing formation, QoE assessment, QoE management, and video or network adaptation.


The deep core drilling is a new challenge with which the exploration engineering will be faced.This article systematically sums up the deep core drilling of Zhaoping fracture zone in east Shandong peninsula,including diamond bit and diamond reamer,drilling parameters,casing material,and deep core drilling operating,which could give dependable reference to similar engineering.


Anthracyclines (ANT) are cytotoxic drugs that are highly effective against a variety of malignancies and are widely used in the treatment of childhood malignancies.But the dose-cumulative cardiotoxicity associated with anthracyclines can affect the quality of life in children, and even cause heart failure. In recent years, with the recognition of the cardiotoxicity of ANT, cardiac monitoring has become necessary to patients treated with ANT and to take early interventions to prevent or treat heart failure.This article reviews the recent advances in the pathogenesis, diagnosis and treatment of ANT related cardiotoxicity.

Key words:
Anthracyclines; Drug toxicity; Cardiotoxins; Heart failure; Dexrazoxane


The Bengal storm of Land fall on May 19,2003 is simulated by the mesoscale numerical model MM5V3,the moving track of storm centre is discussed,the circulation,dynamical and thermodynamic structures afloat,before an after landfall are analyzed.The result show that there are certain errors between the simulated track of storm center san the observed track,but both the tend is moving north-northwest-ward and the simulated results can be referenced.Because of the terrain,the dynamical and thermodynamic structure of the Bengal storm had a series of structural changes.


Recently, crowdsourcing platforms have attracted a number of citizens to perform a variety of location-specific tasks. However, most existing approaches consider the arrangement of a set of tasks for a set of crowd workers, while few consider crowd workers arriving in a dynamic manner. Therefore, how to arrange suitable location-specific tasks to a set of crowd workers such that the crowd workers obtain maximum satisfaction when arriving sequentially represents a challenge. To address the limitation of existing approaches, we first identify a more general and useful model that considers not only the arrangement of a set of tasks to a set of crowd workers, but also all the dynamic arrivals of all crowd workers. Then, we present an effective crowd-task model which is applied to offline and online settings, respectively. To solve the problem in an offline setting, we first observe the characteristics of task planning (CTP) and devise a CTP algorithm to solve the problem. We also propose an effective greedy method and integrated simulated annealing (ISA) techniques to improve the algorithm performance. To solve the problem in an online setting, we develop a greedy algorithm for task planning. Finally, we verify the effectiveness and efficiency of the proposed solutions through extensive experiments using real and synthetic datasets.


Background: India's population which crossed one billion in 2000 is projected to reach 1.53 billion by 2050 making India the most populous country in world. In India 65% of women have unmet need for family planning in the first post-partum year. PPIUCD is highly effective, safe, long-acting, coitus independent and rapidly reversible method of contraception with very few side effects.  Since there is tenfold increase in institutional deliveries due to maternity benefit schemes, postpartum period is potentially an ideal time to begin contraception as women are more strongly motivated and these women would leave the hospital with contraceptive in place.Methods: The present study was a prospective study to assess the acceptance rate of PPIUCD insertion and evaluation of safety of Cu T 380A when inserted within ten minutes of placental expulsion in 100 women delivering at PESIMSR, Kuppam. A specially designed proforma was used to collect the data of women attending hospital between period June 2016 to June 2017.Results: Out of 486 patients who were counselled only 100 women (20.57%) accepted for PPIUCD insertion. The acceptance rate of PPIUCD is 20.57%. Of 100 women who had PPIUCD insertion, 91 were seen at follow up, 76 (78.12%) women were continuing with no complaints and only 15 (16.4%) women developed complications. PPIUCD was found to be safe as there was no reported case of perforation or failure during usage. The complications like expulsion was found to be 1.09%, infection 5.4%, pain abdomen 5.4%, bleeding 1.09% and missing strings 5.4%.Conclusions: PPIUCD was demonstrably safe, having no reported case of uterine perforation. Expulsion rates are low implying more retention rates, thus more effective. Public awareness regarding the concept and advantages of PPIUCD insertion can be improved by mass media approach and creating strategies and training programmes under Government policies.