The wear properties of Ekonol-PTFE-graphite self-lubricating composite against 45 # steel were studied, and scanning electron microscopy (SEM) was used to study the surfaces before and after they had been worn. It was found that when contained less fraction of Ekonol in the composite, the matrix PTFE's crystalline existed as the structure of belt which could be easily destroyed during friction, consequently its wearability was poor, and its wear mechanism was severe surface adhersion. When contained proper fraction of Ekonol, the matrix PTFE's crystalline existed as the structure of net which could effectively prevented destruction of the PTFE's structure of belt during friction, consequently its wearability was increased greatly, and its wear mechanism was fatigue and slight surface adhesion.When contained more fraction of Ekonol, the matrix PTFE's crystalline existed as dispersal, and its wear mechanism was the stripping of crystalline.7figs.,1tab.,9refs.


Extremely heavy rainfall over the Timberlake basin in southwest Virginia on 23 June 1995 caused an earthen dam to fail and resulted in fatalities. The meteorological conditions are examined and reasons for the extraordinary amount of rainfall are postulated. Precipitation estimates from the Weather Surveillance Radar—1988, Doppler (WSR-88D) radar were used in hydraulic models (SMPDBK, DAMBRK, and HEC-1) to generate the failure peak flow and the time of failure.


Let M be a map on a closed surface F2 and suppose that each country of the map has at most r disjoint connected regions. Such a map is called an r‐pire map on F2. In 1890, Heawood proved that the countries of M can be properly colored with ⌊(6r+1+(6r+1)2−24ɛ)/2⌋ colors, where ε is the Euler characteristic of F2. Also, he conjectured that this is best possible except for the case (ɛ,r)=(2,1) , and prove for the case (2, 2). In 1959, Ringel proved the conjecture for the case where F2 is the torus and r=2 . In 1980 and 1981, Taylor proved it for the cases (2, 3), (2, 4), and where F2 is the torus. In 1983 and 1984, Jackson and Ringel proved it for the cases where F2 are the projective plane and the sphere. The case where F2 is the Klein bottle was resolved for r≥3 by Jackson and Ringel in 1985 and for r=2 by Borodin in 1989. We call a graph on F2 an even embedding if it has no faces of boundary length odd. In this paper, we consider the r‐pire maps whose dual graphs are even embedding on F2 and prove that it can be properly colored with ⌊(4r+1+(4r+1)2−16ɛ)/2⌋ colors. Moreover, we conjecture that this is best possible except for the cases (ɛ,r)=(2,1),(0,1),(−2,1) . We prove it for the cases ɛ=2,1,0 with r≥2 .


Thank you for downloading promoting integrated and transformative assessment a deeper focus on student learning. As you may know, people have search numerous times for their favorite readings like this promoting integrated and transformative assessment a deeper focus on student learning, but end up in infectious downloads. Rather than enjoying a good book with a cup of tea in the afternoon, instead they are facing with some infectious bugs inside their computer.


Abstract : The purposes of this research were: (1) validating Kim's (2007) simulation method by applying analytic methods and (2) comparing the two different Robust Parameter Design methods with three measures of performance (label accuracy for enemy, friendly, and clutter). Considering the features of CID, input variables were defined as two controllable (threshold combination of detector and classifier) and three uncontrollable (map size, number of enemies and friendly). The first set of experiments considers Kim's method using analytical methods. In order to create response variables, Kim's method uses Monte Carlo simulation. The output results showed no difference between simulation and the analytic method. The second set of experiments compared the measures of performance between a standard RPD used by Kim and a new method using Artificial Neural Networks (ANNs). To find optimal combinations of detection and classification thresholds, Kim's model uses regression with a combined array design, whereas the ANNs method uses ANN with a crossed array design. In the case of label accuracy for enemy, Kim's solution showed the higher expected value, however it also showed a higher variance. Additionally, the model's residuals were higher for Kim's model.


Using a symmetry-accounting ensemble-averaging method, we have identified the wind in unbounded Rayleigh–Benard convection. This makes it possible to distinguish the wind from fluctuations and to identify dynamic features of each. We present some results from processing five independent three-dimensional direct numerical simulations of a ? = 4 aspect-ratio domain with periodic side boundaries at Ra = 107 and Pr = 1. It is found that the wind boundary layer scales linearly very close to the wall and has a logarithmic region further away. Despite the still noticeable molecular effects, the identification of log scaling and significant velocity and temperature fluctuations well within the thermal boundary layer clearly indicate that the boundary layer cannot be classified as laminar.


(a) The utilisation of such organic waste as that accruing in a City Meat and Fish Market or Slaughterhouses, and (b) Vegetable Waste. Such material as the above usually comes under the control of a City Cleansing Department, and it is from the view point of such an Authority that I propose to treat the subject. The War naturally gave an added impetus to the industry of recovering the valuable residues of such waste as the above. The lessons of economy then learned have survived, until to-day the Salvage operations conducted


Companies are increasingly turning to hybrid clouds, which offer the benefits of both public and private clouds in an integrated system.


More and more products are getting miniature and precise.It makes the micro-hole machining technology develop faster.A series of methods used in micro-hole machining were introduced,and the advantages and disadvantages of these machining methods were analyzed.The prospect of micro-hole machining technology was presented.


1. Introduction: how the idea of a European Criminal Record came to be Constantin Stefanou and Helen Xanthaki 2. The European Criminal Record: analysis Helen Xanthaki 3. The European Criminal Record: the political parameters Constantin Stefanou 4. The European Criminal Record: human rights considerations Alexandra Xanthaki 5. The European Criminal Record in Austria Robert Kert 6. The European Criminal Record in the Czech Republic Jaroslav Fenyk 7. The European Criminal Record in Germany Lorenz Bollinger 8. The European Criminal Record in Greece Maria Gavouneli and Pantelis Traianos 9. The European Criminal Record in Hungary Katalin Ligeti 10. The European Criminal Record in Ireland Ivana Bacik 11. The European Criminal Record in the Netherlands Oswald Jansen 12. The European Criminal Record in Slovenia Katja Sugman and Dragan Petrovec 13. The European Criminal Record in Slovakia Anna Ondrejova 14. The European Criminal Record in Spain Francisco Javier Garcia Fernandez 15. The European Criminal Record in England and Wales Lisa Webley 16. Databases in the area of freedom, security and justice: lessons for the centralisation of records and their maximum exchange Valsamis Mitsilegas 17. A European Criminal Records Database: an integrated model Els de Busser 18. The European Criminal Record: feasible or folly? Helen Xanthaki 19. Conclusions Constantin Stefanou and Helen Xanthaki.


This study aims to improve learning outcomes in English aspects of reading skill ability through the word by word pronunciation learning method. This classroom action research was conducted in two cycles. The subjects of this study were fourth grade students of SD Muhammadiyah 2 Parepare with a total of 10 people. The data collection technique of this research used observation, tests, and field notes. While the data analysis technique used descriptive analysis. The results of this study indicate that the increase in learning for fourth grade students of SD Muhammadiyah 2 Parepare through pronunciation word by word is in the first cycle in the low category with an average score of 53.00, while in the second cycle there is an increase in the high category with an average value. average 85.00. In connection with these results, it can be concluded that the learning method of pronounciation word by word can improve learning outcomes of English aspects of reading skill ability for fourth grade students of SD Muhammadiyah 2 Parepare.


The aim of this systematic review was to indicate and discuss the use of electromyogram in football. For the literature review, following electronic databases were used: Google School, PubMed, Medline and Mendeley for the period from 2005. to 2019. 20 papers were selected for this systematic review based on the established criteria. These studies focused the most on researching the following muscles: m.musculus quadriceps, m.biceps femoris, m.gastrocnemius, m.tibalis anterior and m. gluteus maximus. The review has determined quite a heterogenic choice of topics when it comes to the use of the electromyogram (herein after referred to as: EMG) in football, so the obtained results were grouped based on the similar characteristics. Therefore, the results were categorized according to the following topics: acute effects of the specific football activity, impact of the football strength training, training of kicking on the ball, results based on the difference in sexes, while the rest of the results were sorted in the joint group. Summarizing of the obtained results provides the insight in the multiple possibility for use of EMG in football in order to develop high quality analysis of the neuro-muscle activation of a certain muscle regions of the football players.


Astatid wasps are referred to in literature as specialized predators of hemipterans. We present an unusual prey record for the genus Astata in a Cerrado area (Savannah), at Chapada dos Veadeiros National Park, Goiás State, Brazil. We collected one specimen of Astata lugens Taschenberg carrying an immature cricket (Gryllidae) as prey.


Why do firms exist? The answer to this question has puzzled scholars since at least the 1930s. Given that the invisible hand of the market—with its emphasis on competition and prices—can efficiently coordinate economic exchanges among literally millions of people, why would it ever make sense to try to coordinate such exchanges through a firm— with its emphasis on bureaucracy, rules, and managerial hierarchies? And yet, firms do exist, and they can even prosper. As noted by D. H. Robertson (quoted in Coase, 1937: 388), firms in the economy exist as "islands of conscious power in [an] ocean of unconscious co-operation, like lumps of butter coagulating in a pail of buttermilk."


Governments often see it as their responsibility to support cultural life and at times spend a significant amount of resources in the pursuit of this goal. The present paper analyses whether and how municipalities influence each other in this decision to spend resources on the arts (using data on local government cultural spending in 304 Flemish municipalities in 2002). Following 'central place theory', the focal point of the analysis is the idea that – especially for cultural expenditures – large municipalities (and, specifically, 'central places') may affect their neighbours' behaviour differently than small municipalities. The empirical analysis is supportive of this idea. Indeed, we show that Flemish municipalities' cultural spending is generally positively affected by that in neighbouring municipalities. This pattern is, however, significantly more complex for municipalities neighbouring the 13 largest Flemish cities. größten flämischen Städte ist dieses Muster jedoch erheblich komplexer.


The factors that determine CD4 (cid:2) T cell (T CD4 (cid:2) ) specificities, functional capacity, and memory persistence in response to complex pathogens remain unclear. We explored these parameters in the C57BL/6 mouse through comparison of two highly related ( > 92% homology) poxviruses: ectromelia virus (ECTV), a natural mouse pathogen, and vaccinia virus (VACV), a heterologous virus that nevertheless elicits potent immune responses. In addition to elucidating several previously unidentified major histocompatibility complex class II (MHC-II)-restricted epitopes, we observed many qualitative and quantitative differences between the T CD4 (cid:2) repertoires, including responses not elicited by VACV despite complete sequence conservation. In addition, we observed functional heterogeneity between ECTV- and VACV-specific T CD4 (cid:2) at both a global and individual epitope level, particularly greater expression of the cytolytic marker CD107a from T CD4 (cid:2) following ECTV infection. Most striking were differences during the late memory phase where, in contrast to ECTV, VACV infection failed to elicit measurable epitope-specific T CD4 (cid:2) as determined by intracellular cytokine staining. These findings illustrate the strong influence of epitope-extrinsic factors on T CD4 (cid:2) responses and memory.


Abstract:Classical representations of the miracle cures of Asklepios reflect a model influenced by the agenda of his sanctuaries, particularly in the way they seek to give proof of the experience of incubation and the manifestation of the god's power. The motif of the witness awake found in these representations can be considered evidence of this influence.


For the position/force control problem of multiple manipulators grasping a rigid object, an adaptive position/force control strategy is proposed based on a new sliding mode. With the Jacobian matrix, the joint space model for multiple manipulators can be converted into the task space model. In the process of controller design, we add the force error term into the sliding mode and design the position/force controller directly instead of decoupling the position and the force. The new position/force controller can make the force error converge to zero asymptotically, but the conventional controller can only guarantee it bounded. Considering the uncertainties of the dynamic model, adaptive control is introduced. The Lyapunov stability analysis demonstrates that the proposed strategy can guarantee the asymptotic convergence of position and force error. Simulation results of the two planar two-link manipulators are presented to validate the effectiveness and superiority of the proposed method in comparison with the conventional controller.


In this study, investigation was carried out under in vitro as well as field conditions to explore inhibitors of sorghum grain mold. Phytochemicals, viz., methyl trans‐p‐coumarate (AIC‐1), methyl caffeate (AIC‐2), syringic acid (AIC‐3), and ursolic acid (UA), at different concentrations (500, 750, and 1000 ppm) were tested on spore germination of Alternaria alternata, Curvularia lunata, Fusarium moniliforme, F. pallidoroseum, and Helminthosporium sp. Significant growth inhibition (P < 0.001) was observed against all fungi except A. alternata which was found to be resistant to AIC‐3. Further, two separate sets of field experiments involving spraying of water and F. moniliforme suspension over chemicals treated (1000 ppm) sorghum panicles were done. The levels of protection varied with different treatments which were graded using a standard 1 – 9 rating scale. The Fusarium‐challenged panicles (FCP) showed lesser susceptibility and decreased the rate of infection of grain mold (grade 7.0), compared to simple UA, AIC‐2, and AIC‐1 treatments (7.4, 7.6, and 8.0 grade, resp.). The HPLC quantification of differentially induced phenolic acids in treated sorghum grains substantiated this effect disclosing the higher accumulation of chlorogenic, vanillic, and salicylic acids in FCP. This might be due to defensive induction of these acids by the plants. Although mold control by examined chemicals were lesser than the standard Tilt (grade 5.9), they were found to be nontoxic to mammalian cells under cytotoxicity assay.


During the past 10 years (1999-2009), our research work at the University of Calgary has led us to realize that the challenge of running the Direct Tension Test (DTT) was well worth the effort; because when the samples were prepared properly, the various DTT results and the critical cracking temperature (Tcritical) allowed us to gain many insights into paving asphalt. The DTT and Tcritical techniques have been applied to study various types of paving asphalt, i.e., straightrun asphalt, air-blown asphalt, Polymer Modified Asphalt (PMA), aged asphalt, wax-containing asphalt, crumb rubber modified asphalt, recycled Low-Density Poly-Ethylene (LDPE) modified asphalt, asphalt from different crude sources and asphalt modified with used lubricating oil. In addition to the DTT failure stress and failure strain values, the DTT failure energy and secant modulus were studied, which allowed us to better evaluate the low-temperature properties of paving asphalts. In this paper, experience gained through testing these paving asphalts is discussed and summarized. A comparison of the DTT and Tcritical low-temperature parameters, as well as other tests such as the elastic recovery test, multiple creep and recovery tests, and SuperpaveTM Bending Beam Rheometer (BBR) tests, are discussed.


The article presents the physiological and biochemical features of small-leaved lime growing in urban plantings of different ecological categories: parklands, highways and plantations of sanitary protective zones of industrial enterprises. The content of photosynthetic pigments, secondary metabolites - tannin and ascorbic acid, peroxydase enzyme activity in leaves is significantly influenced by the degree of technogenic impact,


Large vegetations are usually seen in cases of fungal endocarditis and most cases of bacterial endocarditis are associated with a single or multiple small vegetations, most of which are usually too small to be visible on a transthoracic echocardiogram.

We present a case of a middle-aged man with a prior history of moderate rheumatic mitral regurgitation who had a history of having received complete treatment for …


Background: A good maternal and fetal outcome is of utmost importance for any obstetrician and
'partogram' is a very simple and important tool for such assessment.
Objective: To analyse the patterns of labor amongst spontaneous parturient using a WHO modified
partogram and to compare outcome of labor and neonatal outcomes in relation to partogram findings.
Materials and Methods: This prospective study was carried over a period of 18 months on 100 parturients.
Modified WHO Partogram was used to assess the progress of the labor. Parturients were divided on basis of
partogram findings. Group-I (n=64), where parturients partogram remained to the left of alert line, Group-
II (n=20), where parturients partogram remained between the alert and action lines and Group-III (n=16),
where parturients partogram crossed the action line. In these three groups, the maternal and fetal outcomes
were assessed.
Results: Normal vaginal delivery was done in 95.3% of Group-I, 80% of Group-II and 43.75% of Group-III
parturients. Instrumental delivery was done in 1.56% of Group-I, 10% of Group-II and 18.75% of Group-
III parturients. LSCS was done in 3.1% of Group-I, 10% of Group-II and 37.5% of Group-III parturients.
Instrumental / LSCS deliveries were higher in Group-II and Group-III parturients. A large proportion of
newborns of Group-II and Group-III parturients had Apgar Score
Conclusions: The Modified WHO partogram is very helpful in the prediction of maternal and fetal
outcome. It is highly recommended for use in resource deficient medical facilities, where early decision
for delivery or referral can be taken on the basis of partogram findings.

Keywords: Primigravida, Partogram, labor, Alert line, Action line, Modified WHO partogram.


Cancer-related cognitive dysfunction is an important clinical problem that can interfere with the daily functioning, work productivity, childcare, and other responsibilities of women with a history of breast cancer. Risks of cancer-related cognitive impairment include cancer and cancer treatment, as well as patient-related vulnerabilities. There is no established standard of neuroprotective care or treatment for breast cancer-related cognitive impairment.


The purpose of this study is to implement an adaptive, non-intrusive proxy in between a client and SSL/TLS web server using more practical and "middle" approach that can moderate the ongoing and future SSL/TLS sessions. Connection attributes from certificate and SSLProbe results are compared against a set of policies written in JavaScript Object Notation (JSON). The proxy shall handle client session and alerts users when the attributes from the SSL/TLS sites are matched with policy based upon the predefined rules.


We present a variational formulation of Einstein-Maxwell-dilaton theory in flat spacetime, when the asymptotic value of the scalar field is not fixed. We obtain the boundary terms that make the variational principle well posed and then compute the finite gravitational action and corresponding Brown-York stress tensor. We show that the total energy has a new contribution that depends of the asymptotic value of the scalar field and discuss the role of scalar charges for the first law of thermodynamics. We also extend our analysis to hairy black holes in Anti-de Sitter spacetime and investigate the thermodynamics of an exact solution that breaks the conformal symmetry of the boundary.


Abstract : The patent application relates to a method for degelling gelled hydrocarbon fuels in order to produce a product which can be used in aircraft propulsion. Increased safety, in the case of an aircraft crash landing or crash, could be gained if the currently used liquid fuels were replaced by gelled fuels. It has now been found that the sensitivity of gelled fuels toward amines and alcohols--and especially amines--can be used to advantage in the field of aircraft propulsion. According to this invention, metered amounts of gelled JP-4 and JP-5 are subjected to metered amounts of certain amines and are thereby degelled just prior to injection into an aircraft engine for propulsion purposes. Certain alcohols can also be used but are less desirable than amines.


Abstract Freeze-thaw frequencies calculated by eight different counting methods were compared using daily maximum and minimum temperatures from eight north-central United States National Weather Service (NWS) stations. These frequencies were also compared to those obtained using hourly air temperature data from six of the same NWS stations. In addition, the calculated frequencies were compared to measured freeze-thaw frequencies at several depths in a bare soil and a sod-covered soil at the University of Minnesota St. Paul campus climatological observatory. The necessary acceptance of the idealized daily heating cycle when using daily maximum and minimum air temperature data resulted in a higher occurrence of calculated freeze-thaw events than those obtained with hourly data; one method gave 23% more freeze-thaw events with the daily maximum and minimum temperatures. With the freeze-thaw phenomenon centered upon those months in which the mean temperature hovers near O°C, a bimodal frequency occurs at the ...


Power grid planning is the foundation of power grid construction, and mid-long term load forecasting is a key technology in power grid planning, which is of great significance to power grid construction. Firstly, according to the characteristics of 'S' growth of power load on a long-term scale, logistic regression is used to construct a basic model of mid-long term load. Secondly, to reduce the error between the basic model and the actual load, the uncertainty of the error source is comprehensively considered. A probability model of error compensation was constructed using Gaussian process regression. In addition, because of the large amount of input of the error compensation model, there is a problem called "dimensionality disaster". To solve this problem, the principal component analysis method is used to reduce the dimensionality of the input of the error compensation model. Finally, the effectiveness and accuracy of the proposed method are verified by numerical examples.


Asymmetric hydroformylation has been primarily focused on monosubstituted and 1,2-disubstituted alkenes. In this Perspective, progress in enantioselective hydroformylation of terminal disubstituted alkenes is outlined on the basis of different categories of substrates. The origins of the commonly observed low degree of enantioselectivity are discussed. Examples with unconventional regioselectivity are also rationalized.


Life insurance is an effort to reduce the loss risk due to policy holder�s death. In life
insurance, policy holder must pay amount of fund periodically to the insurance
company which is called premium. And insurance company promises to give amount
of fund to the policy holder's family if the policy holder died which is called benefit.
Therefore their liability, insurance company must calculate how much the fund they
should be prepared if the event occur in the future. The fund which insurance company
must prepared is called by reserve premium. There are several method of reserve
premium calculation, some of them are prospective method and full preliminary term
method. Prospective method produces the gross premium reserve that is less than net
premium reserve. By using full preliminary term method, insurance company can
produces the gross premium reserve that is equal to net premium. And the premium
reserve which produced by full preliminary term method is less than the prospective�s
premium reserve if the gross premium reserver is less than the full preliminary term�s
gross premium.


In this study, zirconia (ZrO2) toughened alumina (Al2O3) ceramics(ZTA) with synergistic toughening effect of Silicon Carbide Whisker (SiCw) were prepared, which could be used as dental brackets materials. Firstly, a gel electric double layer was formed though the gelation function of pseudo-boehmite, using ammonium citrate as dispersant, concentrated nitric acid as initiator. Powder of ZrO2, Al2O3 and SiCw were distributed homogeneously in the electric double layer. Followed by drying and sintering, ZTA-SiCw ceramics dental brackets materials were obtained. The optimal preparation technology was selected through orthogonal design by testing the bending performance and the water absorption of samples prepared under different condition. The microstructure and phase composition of ZTA-SiCw ceramics materials were analyzed by Scanning Electron Microscope (SEM) and X-Ray Diffraction (XRD) to explore the synergistic toughen mechanism of ZrO2 and SiCw. Results showed that, the sample which can meet the best requirement was prepared under the following condition: ZrO2 content of 35%, SiCw of 2.5%, and sintering at 1560°C for 6h. This sample was better suitable for making dental bracket.


First,the feasibility analysis on production management system platform of Chinese Herbal pieces and needs of enterprises were verified.Then,logic and system designs were conducted based on business processes.Finally,systemic safety design was made to prevent information leakage and attacks.The application deployment and development of production management system project in YG Pieces Company provides a practical reference for constructing a mature of traditional Chinese medicine production.


The invention discloses a grape increase fertilizer for improving disease resistance. The grape increase fertilizer comprises the following components in parts by weight: 400-500 parts of urea, 300-400 parts of diammonium phosphate, 4-6 parts of zinc sulfate, 4-6 parts of potassium sulfate; 1-3 parts of boric acid, 8-10 parts of humic acid, 4-6 parts of sodium selenite, 10-20 parts of pyrethrum, 5-15 parts of folium artemisiae argyi, 5-15 parts of artemisia capillaris, 5-15 parts of garlic, and 4-6 parts of glycyrrhiza. The grape increase fertilizer for improving disease resistance contains various fertilizers, is rich in nutrition, can meet the requirements of a grape plant on various nutrient elements, and is beneficial to the increase of the nutriture and the synthetic resistance of the grape plant, so that the output of grape is improved; and according to the fertilizer, through interaction of various antiscolic Chinese herbal medicines such as the pyrethrum, the folium artemisiae argyi, the artemisia capillaris, the garlic and the glycyrrhiza, the resistance of the grape is further increased, the capability of the grape on resisting disease insect attack is improved, the usage amount of pesticides and fungicides such as the agricultural agents is avoided or reduced, the safety and the effectiveness are realized, and the influence on human health is avoided.


: Concrete is the most widely used construction material all over the world. It is difficult to find out alternate material for construction which is as suitable as that of such a material from durability and economic point of view. In this project work, sand is partially replaced by industrial steel slag to compare the compressive strength of concrete with conventional concrete for the different curing period i.e. 3, 7 and 28 days. This project was done in three phases. In first phase fine aggregate was replaced by 10% of industrial steel slag. In second phase fine aggregate was replaced by 15% of industrial steel slag and in third phase 20% fine aggregate was replaced by industrial steel slag for M 30 grade of concrete. This paper presents an experimental investigation carried out to study the effects of industrial steel slag as a replacement of sand on strength development of concrete and optimum use of slag as a substitute material in concrete. In this study, concrete of M 30 grade were considered for a W/C ratio of 0.45 with the targeted slump of 100±25 for the replacement of fine aggregate with that of industrial steel slag. These concrete mixes were studied for the properties like compressive strength.


In recent years the advances in cloud computing and virtualization have created the need for autonomic resource provision. The correct provisioning of resources is a difficult task due to variations and uncertainty in workload demands. Most data center workload demands are very spiky in nature and often vary significantly during the course of a single day. Because the resource availability in a data center is generally unpredictable due to the shared feature of the cloud resources and because of the stochastic nature of the workload, severe service level agreement (SLA) violations may occur frequently. To overcome this problem, researcher's attention is diverted towards developing dynamic resource management strategies. In this paper, an autonomic resource controller is proposed that dynamically controls the resource allocation for data center's virtual containers. The controller has two parts: A resource modeler that models the non-linearity of the system by employing different Machine Learning techniques allowing the datacenter to allocate the appropriate resources and a resource fuzzy tuner that dynamically tunes the allocated resources using fuzzy logic to sustain the desired performance taking into consideration the enforcing of service differentiation among clients. Experimental results on a real data center dataset showed that the proposed resource controller can predict future resource needs while still sustaining performance goals stated in the SLA. Also, using the bagging and the boosting techniques along with model tree classifiers was demonstrated to be promising in terms of accuracy and performance.


We consider networks offering tiered services and corresponding price structures, a model that has become prevalent in practice. We develop an economic model for such networks and make contributions in two important areas. First, we formulate the problem of selecting the service tiers from three perspectives: one that considers the users' interests only, one that considers only the service provider's interests, and one that considers both simultaneously, i.e., the interests of society as a whole. We also present an approximate yet accurate and efficient solution approach for tackling these nonlinear programming problems. Given the set of (near-) optimal service tiers, we then employ game-theoretic techniques to find an optimal price for each service tier that strikes a balance between the conflicting objectives of users and service provider. This work provides a theoretical framework for reasoning about and pricing Internet tiered services, as well as a practical toolset for network providers to develop customized menus of service offerings. Our results also indicate that tiering solutions currently adopted by ISPs perform poorly both for the providers and society overall.


Objective: To identify the age of onset of eating disorder behaviours (EDBs) and weight/shape overvaluation in a community sample and to evaluate the association between the age of onset and duration of EDBs with health related quality of life (HRQoL). Method: Data were extracted from the 2008/2009 Health Omnibus Survey (HOS). In 2008, 3034 and in 2009, 3007 participants from a randomly selected sample of households in the Australian population were interviewed for current and age of onset of EDBs. In 2008, mental and physical HRQoL was assessed with the Short Form 12-item instrument (SF-36-2). In 2009, role impairment was assessed with reported days out of role in the past month. Results: There were no significant associations between ages of onset of EDBs with the overall summary measures of physical or mental HRQoL. There was a significant positive association between the duration of EDBs with role impairment. The age of onset of EDBs had a significant negative association with physical HRQoL subscales of SF-36-2 but effect sizes were small. Conclusions: The age of onset of EDBs did not appear to have a significant impact on overall HRQoL measures but duration of symptoms impacted on current role function.


A method has been devised to assure positiveness of k and e in the computation of the k-e turbulence model. That is to express k and e as exponentials of newly defined variables m and n.The validity of the present scheme is demonstrated by computing two-dimensional channel flows starting with constant initial flow and reversed initial flow. Fully time-implicit three-point wall function method is used as the solid wall boundary condition.


The MAK value of 5 ml/m3 for hydrogen sulfide was based on avoiding neurotoxic effects on the olfactory epithelium and considerable odour annoyance. Although a NOAEC (no observed adverse effect concentration) of 10 ml/m3 could be derived from several sub-chronic studies in rats and mice for damage to the epithelium (2007 documentation, published in English translation in 2013; documentation "Hydrogen sulfide" 2013), the evaluation of odour annoyance was extrapolated from an earlier study with humans that only investigated concentrations up to 0.15 ml/m3. Odour annoyance was significantly increased at this concentration (Winneke 1992). It was evident from the extrapolation of these results that considerable odour annoyance can be expected with exposure levels of 5 ml/m3. It was not possible at the time to evaluate conclusively whether this odour annoyance interferes with occupational activities or in some other way results in adverse effects (documentation "Hydrogen sulfide" 2013). When the MAK value was established, the only available human data for sensory or cognitive effects of hydrogen sulfide after short-term exposure in the range of 5 to 10 ml/m3 were published only as an abstract reporting the preliminary results of a volunteer study with exposure to maximum concentrations of 5 ml/m3 (Fiedler


Ultra-Thin-Body and Back-oxide Fully-Depleted Silicon-On-Insulator (UTBB-FDSOI) MOSFETs are the most recent and advanced Silicon-On-Insulator (SOI) architecture proposed to overcome the down-scaling limitations of traditional bulk devices. The UTBB-FDSOI architecture has already been proved very attractive for RF-mmW circuits thanks to the excellent reported RF figure of merits (FOMs). In this article, we report on an experimental investigation of the back gate biasing impact on the high-frequency (HF) noise performances of an advanced 22 nm UTBB-FDSOI technology developed by GLOBALFOUNDRIES. For the lower gate voltages, the back gate biasing was shown to decrease by one third the equivalent noise resistance (Rn). Moreover, a 3 dB increase for the associated gain (Ga) was achieved at Vg=0.3V. A relaxed contacted-poly-pitch was also shown to decrease Rn by 11%.


The purposes of this study were (1) to determine the effect of computer-assisted cloze exercises on the acquisition of English as a second language of selected community college students, and (2) to determine if computer-assisted cloze exercises were more effective for Spanish as opposed to Chinese native language students. It was hypothesized that (1) students using the CAI exercises would receive higher posttest scores than students not using the exercises, and that (2) within the experimental group, Spanish native language students would receive higher scores on a posttest of grammar proficiency than Chinese native language students. The sample for the study was composed of thirty-eight community college students of various ethnic backgrounds. Measures of achievement were obtained through the administration of the ALFA test of grammar proficiency. The Mann-Whitney U test and the t test were used to determine the retention or rejection of the hypotheses. Statistical analyses indicated that (1) computer-assisted cloze exercises were not, overall, more effective than traditional instruction, , and (2) Spanish and Chinese students did not differ significantly in posttest scores of English language proficiency. Recommendations are made for future research iii concerning teaching methods and materials, language proficiency measurement instruments, and computer-assisted exercises.


The structure of a website and the location of its main image attributes, presence of scarce text, search function and celebrity images, directly influence the user's perception of the visual appeal of websites, as well as their evaluation. In this study, a study and subsequent analysis of the booking websites (www.booking.com) and hotels (www.hoteles.com) are carried out, using the eye tracking technique analysis of these attributes, except for celebrity images, since it is not the case of this type of communication between company and user. A questionnaire and a cluster analysis are also carried out. The target audience chosen is the millennial population. In the results, it is noted that the presence of a single main image (Hoteles) obtains a greater number of fixations than when two (Booking) are used, that the simple design of the Booking website obtains a significant preference than that of Hoteles, which has more text and communicative elements, and the importance of the presence of the search engine, with greater user preference for the location of the Booking website.


The BMA is calling for equal value to be placed on mental and physical health, particularly that of the most vulnerable members of society.

Its report says that the physical health problems of patients with mental illness are often not properly dealt with and that the mental health of patients with physical illnesses is also often neglected.1

The association points out that in comparison with the general population men with mental health problems die, on average, 20 years earlier and that women die 15 …


JAAPA Journal of the American Academy of Physician Assistants www.JAAPA.com One of my favorite things to do is to accompany a group of students to a school and watch them teach. They are fi rst-year physician assistant (PA) students, and as part of their PA practice course, small groups of them go out into Philadelphia public schools and teach the kids about health-related topics. Two weeks ago I accompanied a group to a school in the city's Wissahickon neighborhood. Standing in the science room, under a banner that read "You're Made of Atoms. You Have Mass. YOU MATTER," six PA students in crisp white coats taught a room full of fi fth-graders about viruses, bacteria, and the importance of hand washing. Everyone got a piece of candy and a bottle of hand sanitizer at the end. This afternoon, we've piled into a couple of cars and driven to the Southwark section of the city. School has just let out, and traffi c around the school is heavy. The crossing guard helps us cross the street. "Come on, kids." She smiles and waves our overgrown group across. My students are spending time in the afterschool program. Armed with colored pencils and a bag of little foam squeezeballs, they're teaching a group of 25 thirdand fourthgraders about stress. After a brief presentation about what stress is, the kids are split into smaller groups and rotate through four stations: in one, they color a face that shows how they are feeling today; in another, they practice yoga; in a third, they exercise, playing "Simon says" and doing jumping jacks; and in the fourth, they talk about stressful experiences they've had. The classroom is crowded, so the exercise and yoga groups are out in the hall. I'm watching a little girl, probably 8 or 9 years old, with dark eyes that are framed by glasses. Her black hair is pulled back in a ponytail, and she's wearing tiny gold earrings and bright red tights. She's in the hall with the yoga group, but she is not participating; she's just sitting on the fl oor, leaning against the wall; the girl sitting next to her is holding her hand. As the other kids in the group laugh and chant "I am strong" in time to their breathing, she rests her head on her friend's shoulder. It's time to switch stations, so the yoga group moves back into the classroom and settles into a circle with two PA students who start talking to them about stressful experiences. They explain that communicating with other people about what is bothering you can help you feel better. They ask the kids if they've had anything stressful happen to them recently. To break the ice, one of the students says, "I had someone say something really upsetting to me a couple of weeks ago." She goes on to describe how she called her sister, talked with her about it, and ended up feeling much better. The other student talks about the stress she felt when she had a really diffi cult test last week; she talked with classmates, made a study plan, and did fi ne on the test. A fourth-grader's hand shoots up. "I had a test last week." "Were you worried about it?" "Yes." "Did you study and do okay?" The fourth-grader nods and smiles proudly. "Has anyone else had anything happen that stressed them out?" At fi rst the group is quiet; then the little girl in the red tights tentatively raises her hand. "Yes? Did something that was diffi cult happen to you recently?" my student asks. The girl answers quietly, "Trump hates Mexicans." There is a long moment of silence. My student hesitates; then she leans forward till she's at eye level with the little girl in the red tights. "But you have so many people who love you and care about you: your parents, your teachers, your family, and your friends." The girl responds with an almost imperceptible nod, then looks down at the fl oor. Later that afternoon, as we walk back to the car, my student shakes her head. "How do you answer that? I had no idea what to say. What do you say to an 8-year-old who thinks the president hates her?" "Sometimes there is no answer. Sometimes there's nothing you can say," I reply, "except what you told her." JAAPA Paying attention


The tradition of modern political economy is founded upon attempts to show how a market economy of autonomous individuals can function smoothly in the absence of a central authority to coordinate economic activity. This has become known, for obvious reasons, as the coordination problem. As suggested by the title of this article, to confront the coordination problem is to focus upon the question, 'what makes a market economy?'. In the pages that follow, I argue that the answer to such a question lies not, as we might expect, in the realm of economics, but in that of moral philosophy. In order to sustain this argument, I revisit debates about the essence of the market economy which are to be found in the history of economic thought literature, but which are almost entirely ignored by modern economists.


The newspaper firms are facing an innovation, the e-newspaper published on e-paper technology. The e-paper is reflecting, giving the same reader experience as paper (such as high contrast and the possibility to read in sunlight) and is thin, flexible and non-sensitive. The e-newspaper combines the readability and overview from the printed newspaper with the possibilities of online media such as constant updates, interactivity and video, and is predicted to replace the printed edition in the long run.


Getting funding for CAI in the education of health professionals is a tough dollar. For resourceful, scholarly applicants with a scientific approach, support is out there.


This paper presents the application of quasi-orthogonal space time block coding (QO-STBC) with two constant feedback scheme. The feedback scheme employs two-constant feedback paths. This is applied to four transmit and N receiver antennas to achieve full transmit diversity gain and full data transmission rate with simple-wise decoding complexity at the receiver side. This proposed feedback scheme achieves full diversity order of 4 ×N at the receiver side by canceling the self-interference from adjacent symbols in QO-STBC codeword. The simulation results confirm that the feedback scheme significantly improves the performance over all existing feedback methods with reduced computational complexity and is based on the channel state information (CSI) available at the receiver side.


Camellia oleifera is one of the most important oil trees in the south of China.In this paper,the plantations of C.oleifera in Wuzhishan region of Hainan province were investigated,and the yield and nutritional status of C.oleifera were analyzed too.The results showed that the yield of C.oleifera was different among different regions.There was significant difference in the content of nutritive elements among different C.oleifera plantations.This study will provide references for the scientific management and further development of C.oleifera in Wuzhishan region.


Through the comparison in specialty setting between the two municipal college and university of Guangzhou,and other 20 universities located in Guangzhou,it is found that the former two have fallen far behind the latter universities,in specialty class completeness,and specialty quality.While regarding the specialty structure's fitness for the structure of the three big industries,the municipal college and university don't enjoy obvious superiority to other universities located in Guangzhou.As a result,the municipal two universities should assume the stance of application,seek for the dislocation development and form their own features in specialty setting.


Resistivity, reversible magnetization, and Josephson plasma resonance (JPR) data for Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub 8} with columnar defects (CD) show that two liquid phases exist above the irreversibility line. They differ by the c-axis correlations in pancake positions. We explain the existence of two liquids with different c-axis correlations and transition between them in some temperature interval exploring the particle-hole symmetry in the free energy functional for pancakes inside CD. This functional accounts for magnetic interaction of pancakes, their interaction via Josephson coupling, and pinning by CD. {copyright} {ital 1998} {ital The American Physical Society}


Investigations were carried out concerning the sorption properties of the halogenated alkanes CF 3 Br and CF 2 Cl 2 by PVC-powder. Exposure to 5.5% (v/v) in air leads to the equilibrium within one day and three days, respectively. However, much more CF 2 Cl 2 than CF 3 Br had been sorbed. This difference was found with the sorption isotherms as well. While the adsorption curve of CF 3 Br showed typical condensation effects, that of CF 2 Cl 2 is in accordance with Langmuir's equation


PURPOSE: One of the proven effects of Ozone Therapy, is the releasing of Growth Factors from Platelets. Some other therapies can have similar effects. Autologous Therapies can be defined as "The therapy that is done by transferring cells, tissues, body liquids originating from the recipient rather than from donor." The purpose of this presentation is to give information on those therapies.

DISCUSSION: There are several therapies in this group, such as Stem Cell Therapies, Dentric Cell Vaccine Therapy, Autologous immune enhancement therapy, etc. But most of them are so difficult that we can not practise at office conditions where some therapies can be done at small clinic and private offices. These are; PRP (Platelets Rich Plasma) / CGF (Concentrated Growth Factors) / PRF (Platelets Rich Fibrin). The differences among those therapies and common points are evaluated.

RESULTS: All those therapies have some beneficial effects.

CONCLUSION: Integrative Medicine and Autologous Therapies look as future medicine. We can learn more on these therapies.


Abstract 3. Recipient's Catolog No. 5. Report Date April 1970 6. Performing Organization Code 8. Performing Organization Report No. L-7115 10. Work Unit No. 126-13- 11-01-23 11. Contract or Grant No. 13. Type of Report and Period Covered Technical Note 14. Sponsoring Agency Code In this analysis, the techniques of geometrical acoustics are employed to study the effect of variation of the jet-temperature profile upon propagation of sound in the jet. It is shown that the temperature profile of the jet can be shaped to cause the jet flow to act as a channel for the sound. Further, a simple analytical expression which predicts the occurrence of such phenomena in a nonspreading jet is obtained. This expression also seems to be approximately valid for a spreading jet. -~ 17. Suggested Key Words by Author(s) Jet noise Ray tracing Wave equation 19. 21- Security Classif. (of this report) Unclassified 18. Distribution Statement Unclassified - Unlimited 20. Security (of this page)


CZB medium was used as a base medium to study the function of taurine, glucose and porcine oviductal epithelial cells system in the culture of blastomeres isolated from mouse 4?8-cell embryos. These results showed addition of taurine in CZB did not significantly affect the blastocyst rate of blastomeres isolated from mouse 4, 8-cell embryos (29% vs 30% and 14% vs 14%) (P 0.05). Addition of glucose in CZB had a significant effect on the blastocyst rate of blastomeres isolated from mouse 4,8-cell embryos (29% vs 36% and 14% vs 19%) (P 0.05). Addition of taurine did not have a significant effect on the blastocyst rate of blastomeres isolated from mouse 4?8-cell embryos respectively(36% vs 38% and 19% vs 20%) when glucose had been added in CZB(P 0.05). The cell number of blastocysts derived from blastomeres isolated from mouse 4, 8-cell embryos were not different significantly(10.44±1.24)~(12.43±1.18) and (7.57±0.97)~(8.48±1.16) respectively (P 0.05). The blastocyst rate of co-cultured blastomeres isolated from mouse 4, 8-cell embryos were 47% and 26%, respectively; the cell number of blastocysts derived from co-cultured blastomeres isolated from mouse 4, 8-cell embryos were 17.57±1.13 and 11.43±0.92 , repectively. These were more than those of blastomeres in the controls(P 0.05).


Studied on the scale,function,cross section of eight new reconstructed streets in Kunming,and greening structural style,plants' growing and management,affiliated facilitates and whole landscape of these streets with the methods of measuring practically,investigating and statistics of data and concluded that the greening style of new reconstructed streets in Kunming city is the combination of arbors,shrubs and grass,and that the kinds of plants are rich,but affiliated facilitates of streets are short and the whole landscape is single.Put forward some corresponding suggestion and measures to be references for future reconstructed engineers of city streets.


As a knowledge imparting activity,guided reading in universities plays a supplementary role in higher education.University libraries shall guide reading to foster students' comprehensive qualities,broaden the guided reading idea and strengthen the guided reading activity.


The article is dedicated to the journalistic work of Albert Camus, the French writer and essayist, who was also an outstanding journalist and whose example of a tireless fight for the truth and human dignity is especially important nowadays.


Simultaneous robust estimates of location and scale parameters are derived from minimizing a minimum‐distance criterion function. The criterion function measures the squared distance between the pth power (p > 0) of the empirical distribution function and the pth power of the imperfectly determined model distribution function over the real line. We show that the estimator is uniquely defined, is asymptotically bivariate normal and for p > 0.3 has positive breakdown. If the scale parameter is known, when p = 0.9 the asymptotic variance (1.0436) of the location estimator for the normal model is smaller than the asymptotic variance of the Hodges‐Lehmann (HL)estimator (1.0472). Efficiencies with respect to HL and maximum‐likelihood estimators (MLE) are 1.0034 and 0.9582, respectively. Similarly, if the location parameter is known, when p = 0.97 the asymptotic variance (0.6158) of the scale estimator is minimum. The efficiency with respect to the MLE is 0.8119. We show that the estimator can tolerate more corrupted observations at oo than at – for p < 1, and vice versa for p > 1.


The Indian Council of Medical Research initiated a multicentric trial with prostaglandins in 1976 to assess the safety and efficacy of their use in midtrimester abortions. PGF2, and 15-Me-PGF2, were compared using the intra-amniotic (I.A.) route. 15-Me-PGF2, was also evaluated by extra-amniotic (E.A.) route, With intra-amniotic instillation, success rate was 88.1 per cent with PGF2, and 93.0 per cent with 15-Me-PGF2, within 48 hours and by the extra-amniotic route it was 78.1 per cent within 36 hours. The mean induction-abortion interval was 19 hours with I.A. and 14.8 hours with E.A. Abortions were complete in 48.8 per cent of the women following I.A. PGF2,,56.0 per cent following I.A. 15-Me-PGF2, and only 23.0 per cent following E.A. administration. Vomiting and diarrhoea were the most commonly reported side effects. Cervical injuries were 4.7 per cent with I.A. PGF2u, 1.4 per cent with I.A. 15-Me-PGF2, and only 0.6 per cent with E.A. route.


In men, the long‐term consequences of low serum levels of sex steroids, vitamin D metabolites, and insulin‐like growth factor 1 (IGF‐1) on the evolution of muscle mass, muscle strength, or physical performance are unclear. Moreover, there are no data about the relationship between these hormones and incident sarcopenia defined as low muscle mass and function. The aim of this study was to determine whether the baseline levels of sex hormones, vitamin D metabolites, and IGF‐1 predict changes in muscle mass, muscle strength, physical performance, and incident sarcopenia.


We survey several of the theoretical models that have been applied to the analysis of the GATT/WTO dispute settlement process. These include repeated game models, which emphasize the punishment aspect of dispute settlement, and incomplete contracting models, which emphasize the 'gap-filling' aspect. Our analysis emphasizes the implications of these models for the strengthening of the dispute settlement process under the WTO and for its application to the TRIPS agreement. We also discuss how models of settlement bargaining can be applied to obtain empirical predictions about which cases will actually proceed to an actual finding by the dispute panel.


13 March 2008 Apprentices Making A Positive Contribution To The Territory Apprentices working at some of the Territory's most popular attractions have a positive future ahead of them, Parks and Wildlife Minister Len Kiely said today. "In February alone we had seven young Territorians begin their apprenticeships at some of our most popular attractions such as the Territory Wildlife Park and Windows on the Wetlands," Mr Kiely said. "This includes full-time apprentice Joshua Bonson who began a Certificate III in horticulture at the George Brown Darwin Botanic Gardens last month. "Joshua is a hard-working Territorian who many people also know as an up and coming artist he was a finalist at last year's Telstra National Aboriginal and Torres Strait Islander Award. "Joshua joined school-based apprentices Jarrod Benton and Brentley Plummer who began their Certificate II in Conservation and Land Management at the Botanic Gardens last year. "By providing apprenticeships to young Territorians we are increasing the Territory's skill base. "These Territorians may one day decide to work in other parts of the Territory so it is our role to ensure they have all the necessary skills they need to be job ready. "While Joshua, Jarrod and Brentley are undertaking their apprenticeships, they will make a positive contribution to the visitor experience at the Botanic Gardens. "They will learn what is required to maintain a public park, such as identifying plants and weeds and doing what's best for a plant's health. "Importantly, they will learn particular aspects of garden maintenance and plant presentation so visitors to the Botanic Gardens can enjoy what we have on offer. "I've heard positive things about Joshua, Jarrod and Brentley and wish them – and all other Territory apprentices – every success in achieving their personal goals." Mr Kiely said Northern Territory Government apprenticeships are advertised regularly and include certificates in tour guiding and captive animals.


This technique is a CAM block comprising a number of vertical strings perpendicular to the semiconductor substrate; A peripheral circuit configured to program a selected one of the CAM cells CAM cells included in the vertical string; And one of the plurality of word lines coupled to the vertical string and the n-th word line and the n-th to the first n-1 and the program voltage to the first n + 1 word lines adjacent to the word line is at the same time, the CAM cells to the CAM cells coupled to the first n-1) to (n + 1 word lines at the same time, the program includes a semiconductor device and its method of operation of a control circuit for controlling the peripheral circuits.


In The Stoic Comedians Hugh Kenner asserts that "the Stoic is one who considers, with neither panic nor indifference, that the field of possibilities available to him is large perhaps, or small perhaps, but closed." While I would call Johnson a Stoic (that somewhat oxymoronic thing, a Christian Stoic) only in a limited and special sense, I think that Kenner provides a good point of departure for discussing Rasselas, a book about the endlessness of human quest and the closed field of human scope.' The gap between the two furnishes the satire of Johnson's epistemological fiction. The world presented in Rasselas consists of both objects and ideas that tend to form mutually exclusive and exhaustive sets. Man finds himself in a closed field, yet finally he is not one himself, and this makes for his misery as well as his hope. The book opens, as did Johnson's Life of Savage, on a monitory note that anticipates the ending; suspense, it is clear, is not an objective:


16518 Background: A phase I clinical trial of IV weekly topotecan (T) in combination with carboplatin (C) for recurrent ovarian cancer (OC) showed less toxicity than the daily X 5 T with C schedule...


: Based on an ethnographic approach to the daily life of women artists, this article explores the use of the mobile methodology to understand the experience of time and space in the context of the transformations of work and the contemporary urban experience. It is intended to shed light on the tensions and strategies of working mothers in the artistic sector when they have to reconcile their productive, reproductive, and leisure time in the city of Santiago de Chile. Multisite fieldwork was conducted for this research during 2018 and 2019, with a mobile methodology of monitoring the activities and daily movements of the study participants. This involved moving with them through the various public and private contexts of their personal and working lives. I conclude, based on the analyses that women artists make a perma-nent effort to organize a routine in which the times and spaces of art, leisure, and motherhood are inevitably interpenetrated. Gender inequality impacts not only on the overburdened work-life balance of the double day, but also the quality of their leisure time and their creative work. The use of a mobile methodology allowed me to capture in situ this daily time management, and the gendered costs of coping with a lifestyle marked by temporal overlap-ping and daily mobility in the city. With these theoretical and methodological choices, the article contributes to discussions on the value of mobile methodology and renewed uses of ethnography by distancing itself from traditional approaches to social research, which tend to construct their objects of study and approach actors in fixed contexts within the city.


Summary Fracture information is vital to different parts of the petroleum industry. Several methods can provide this information. Among these methods, AVAZ fracture analysis is one of the most accurate as they measure anisotropy for this analysis. Two kinds of AVAZ fracture detection methods (Ruger's equation and azimuthal Fourier coefficient) have been investigated in this study to find how valid they are. To approach this mean, the results of these AVAZ methods have been compared to the fracture density and fracture proximity post-stack attributes which are widely used in the industry. This comparison showed AVAZ methods are consistent with the mentioned post-stack attributes and they are more precise.


Eikonal solvers in the Cartesian coordinates often suffer from source singularity due to the plane-wave assumption for the wavefront near the source point. Traveltime errors induced by the source singularity near the source point will spread to the whole domain and reduce the accuracy of subsequent traveltimes. The source singularity can be avoided if the eikonal equation is formulated and solved in the polar/spherical coordinates. However, the grid in the polar/spherical coordinates will cause sparse non-uniform resampling in the region far away from the source point after the traveltime is transformed back to the Cartesian mesh, hence reducing the uniform accuracy in this region. To deal with the source singularity and maintain uniform accuracy, we introduce a hybrid fast sweeping method that computes the traveltime near the source in the polar/spherical coordinates and computes the traveltime far away from the source in the Cartesian coordinates. The source singularity near the source point is resolved in the polar/spherical coordinates, and the uniform accuracy is achieved by switching to the Cartesian coordinates away from the source point. Numerical examples are presented to demonstrate the method.


Antibacterial potential of metallic silver nanoparticles (AgNPs) is considered to be influenced by their size and stability. In this study, the stable AgNPs capped with poly (4-styrenesulfonic acid-co-maleic acid) or PSSMA were successfully synthesized by using a chemical reduction method. The PSSMA-stabilized AgNPs (PSSMA-AgNPs) were characterized and tested for antibacterial activity against eight bacterial strains. Transmission electron microscopic studies showed that PSSMA-AgNPs were monodisperse spherical particles with an average size of 5.21 nm. From bacterial growth curve studies, PSSMA-AgNPs exhibited an antibacterial effect on Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Staphylococcus aureus ATCC 6538p, Staphylococcus aureus ATCC 43300, Staphylococcus epidermidis ATCC 12228 and Bacillus subtilis ATCC 6633) and Gram-negative bacteria (Escherichia coli ATCC 25922, Enterobacter aerogenes ATCC 13048 and Pseudomonas aeruginosa ATCC 27853). Moreover, the Gram-negative bacteria were found to be more susceptible to the AgNPs.


Background: Local carotid pulse wave velocity (PWV) estimation is challenging due to a complex anatomy and associated wave reflections [1]. Wave interference is both blood pressure (BP) and position dependent, hence causing nonlinearity in the spatiotemporal PWV estimation [2]. In lack of beat-to-beat quality assessment [3], we propose a method to quantify this nonlinearity and thereby introduce a quality indicator (QI) for reliable PWV estimation.


Introduction 2 Different kinds of grammar 2 Developing grammatical competence 5 On the scope and sequence of grammar instruction 9 Using instructional technologies (IT) for grammar learning 10 Conclusion 12 References 12


Preliminaries. We consider a real-valued function f(x) on an interval [a, b]; Lebesgue measure on [a, b] will be denoted by A. If 91 and 92 are collections of intervals then A,S is the measure of the point set covered by 91, while -9-92 iS the collection of intervals in 91 which are not in 92. The notation f(c, d) will mean the slope of the chord connecting (c, f(c)) with (d, f(d)). If p is a partition, that is, a finite set of points containing a and b, then 7r(x) is the polygonal approximation to f(x) on p. We assume that f is rectifiable or, equivalently, of bounded variation (i.e., If = lubli 7r < oo, where 17r is the length of the graph of 2r); thusf is continuous except on a countable set. The upper (lower) right (left) derivates are measurable; in fact, at points of continuity of f, we have for the upper right derivate:


The utility model relates to a thermocouple induction type artificial gas range with a backfire protection device, which comprises a range base body, wherein at least one burner with a thermocouple induction probe is fixedly arranged on the range base body, a knob switch is arranged on a base body corresponding to the burner; a gas inlet tube extends into the base body and is communicated with an injecting tube of the burner by a valve assembly, a thermocouple electromagnetic valve body which is capable of conducting/cutting off gas supply is arranged at the place where the gas inlet tube extends into the lower part of the knob switch; a branch tube communicated with a nozzle of the injecting tube is arranged at one side of the thermocouple electromagnetic valve body; a box-shaped backfire metal cover body is arranged at the top end of the position of the injecting tube and a valve assembly nozzle; a temperature controller is fixed on the backfire metal cover body; the base body is further provided with a pulse controller; and the valve assembly, thermocouple electromagnetic valve body, the temperature controller and the pulse controller are electrically connected with one another. The gas range has simple and reasonable structure and is capable of cutting off the gas supply in time in case of backfire so as to protect a range panel and elements in the range, prolong the service life of whole product and improve safety.


The soil types and geochemistry characters in Heilongjiang Wuchang area were analyzed.The results showed that soil conditions and geochemistry characters were the main reasons for super-quality and high-yield Wuchang rice.


The exponential growth in wireless network faults, vulnerabilities, and attacks make the WLAN security management a challenging research area (29). Data mining applied to intrusion detection is an active area of research. The main reason for using data mining techniques for intrusion detection systems is due to the enormous volume of existing and newly appearing network data that require processing. Data mining follows anomaly based intrusion detection. The drawback of the anomaly based intrusion detection in a wireless network is the high rate of false positive. This can be solved by a designing a hybrid intrusion detection system by connecting a misuse detection module to the anomaly detection module. In this paper, we propose to develop a hybrid intrusion detection system for wireless local area networks, based on Fuzzy logic. In this Hybrid Intrusion Detection system, anomaly detection is performed using the Bayesian network technique and misuse detection is performed using the Support Vector Machine (SVM) technique. The overall decision of system is performed by the fuzzy logic. For anomaly detection using Bayesian network, each node has a monitoring agent and a classifier within it for its detection and a mobile agent for information collection. The anomaly is measured based on the naive Bayesian technique. For misuse detection using SVM, all the data that lie within the hyper plane are considered to be normal whereas the data that lie outside the hyper plane are considered to be intrusive. The outputs of both anomaly detection and misuse detection modules are applied by the fuzzy decision rules to perform the final decision making. Hybrid detection system improves the detection performance by combining the advantages of the misuse and anomaly detection (33).


Structural mapping in northern Peloponnesus reveals the emergence of an E-W striking, more than 70km long, low angle detachment fault dipping to the north beneath the Gulf of Corinth. This paper describes four north-south structural cross-sections in northern Peloponnesus. Structural and sedimentological field observations show that in the studied area the normal faults of northern Peloponnesus branch at depth on this major low angle north-dipping brittle detachment. The southern part of the detachment and the related normal faults are now inactive. To the north, the active Helike and Aigion normal faults are connected at depth with the seismically active northern part of the detachment beneath the Gulf of Corinth.


Temperature is among the most influential factors in animal biology, and especially thermal fluctuations are key determinants of life history traits for ectothermic organisms. Diet characteristics add complexity to the effect of temperature on animals' life history traits. This is even more intricate in phytophagous insects that develop inside hosts. Here, using the seed beetle Zabrotes subfasciatus Boheman we tested life history trait response to five different ambient temperatures (15, 25, 30, 35, and 45 °C). We also tested the effect of the interaction between temperature and diet on the weevils' life history traits and estimated fitness for individuals at different temperature and food supplementation conditions. We first showed that the relationship between temperature and egg size and number, and adult emergence is altered by sugar ingestion, mainly at 30 °C. Additionally, we showed that temperature and sugar ingestion have opposite effects on longevity, with this trait being heightened by sugar ingestion at 25 °C. Interestingly, except at 35 °C, egg size shows a response that opposes the temperature‐size rule, which states increasing environmental temperature reduces insect's size. Finally, excluding the extreme temperatures, fitness patterns increased with temperature and the clearer effect of parental feeding on fitness was registered at 30 °C. Since 30 °C is the temperature at which our weevil populations are maintained in the laboratory, these results point to a possible long‐term "acclimation effect" on the weevils' fitness. Thus, testing the effect of the temperature experienced by the original population on the experimental weevils' fitness might shed light on the biological explanation of the observed temperature vs diet interaction.


The use of an object-oriented approach in software engineering has proven to be successful for many years, but in the fields of mechanics and automation it has been ignored for long. The Tetra Pak Carton Bottle automation team believes that a switch from a function-oriented architecture to an object-oriented one would be of benefit not only to them but also any department which is involved with development, production, and maintenance of filling machines.

Many product projects of today make the mistake of having its participants jumping straight into the implementation part of the project while skipping the work of first defining requirements of what the product shall accomplish. People in general like to start by doing the how of the project without first focusing on the what.

But if the needs of other product concerned are overlooked then there is a risk of an important part being left out, perhaps leading to a weaker product. This master thesis focuses on the what part of a development project where an object-oriented architecture shall be deployed for Tetra Pak's development, production, and maintenance of machine systems. During the master thesis requirements from various stakeholders were defined based on interviews and discussions held with various Tetra Pak departments.

The result, the requirements, show that Tetra Pak has several areas which would be benefited by an object-oriented architecture by making Tetra Pak's machines more modular and the maintenance of them simpler.


This paper investigates the choice of airline itineraries in dynamic settings using a tailored stated preference survey. The paper hypothesizes that airline itinerary choice is not a one-time event, but a continuous process during a certain time frame. Consumers can choose either to purchase an itinerary, deferring choice up to the end of the sales period, or completely declining the purchase. Understanding such consumers' behavior is specifically relevant to the tourism industry, where firms are extensively utilizing internet websites to offer their products (e.g., airline tickets, hotel rooms) to consumers. The paper describes the stated preference survey with real itineraries of various airlines on medium and long-haul routes. Choice sets are composed with dynamic and static variables and socio-economic variables. Questionnaires were distributed electronically among various groups of respondents, yielding a sample of 914 persons. Results show that (i) itinerary choice deferring takes place, with differences between tourists and business travelers, (ii) the decision whether to defer choice is affected by dynamically changing variables and by the length of each respondent's allocated choice period, and (iii) the proposed methodology is adequate for investigating choice in dynamic settings and thus indicating its potential for further research in transportation planning and in tourism.


Renal artery variations may relate to the origin, course, and end branches of renal artery divisions. To describe the morphology and topography of renal arteries in melanoderm living in Benin. This was a retrospective study from March 1, 2016 to April 31, 2017, i.e. 14 months. The study population consisted of all injected abdominal CT scans clearly highlighting the renal artery and its branches from the CT scan unit of CNHU-HKM. The data collected was entered into CSPro 6.2 software and then processed and analyzed using stata 13 software. The right renal arteries originated in an antero-lateral position on the aorta in 84.4% of cases, while those left in a mediolateral position in 45.9% of cases. They were projected mainly opposite L1 on the right and L2 on the left. Regarding their courses, all the arteries studied were concave posteriorly in the transverse plane and mostly concave above and upwards. Finally, the renal arteries mostly end by bifurcating into anterior and posterior branches in 88.5% of cases, by trifurcating in 1.5% of cases, rarely they divide into 4 branches. The renal arteries arise on the right in an antero-lateral position on the aorta and on the left in a medio-lateral position. They are lower located on the left with a concave path backwards and upwards then head upwards. Finally, they end by bifurcating. This knowledge is essential for patricians working on the kidneys.


The transition of field-temperature in the warmer district of Kyushu was measured in wheat cultivating season; and the results were shown in Table 1.The surface-soil temperature in early summer seem too high for the crop growth.The lasting low temperature that causes cold damage does not frequently occur in this district.The plant cover influences the vertical distribution of temperature in May. (Fig. 1)The relations between the temperature in the meteorological observation field and that in the cultivating field are approximately linear. (Table 2)The daily-range decreasing index (p) of soil-temperature and thermal-diffusivity (a2) are shown in Table 3.


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Background: Rituximab (RTX) is a chimeric anti-CD20 monoclonal antibody being increasingly used in management of pemphigus. Various studies show a lack of any uniform treatment protocol. The objective of the study was to assess the effectiveness of RTX in patients of pemphigus receiving serial low doses of RTX (500 mg; maximum of 4 doses; 2 weeks apart). Methods: It was a prospective observational review of 40 pemphigus patients to assess the proportion of patients achieving complete remission after serially receiving low dose RTX, time and number of doses required to achieve complete remission (CR), proportion of patients who responded partially or didn't respond or relapsed after achieving CR. Additionally, the study was done to find whether a correlation existed between age, gender, and site of lesion and RTX administration. Results: 40 pemphigus patients followed up for a mean duration (MD) of 174.15±95.67 days received 4 doses of RTX (500 mg) irrespective of the disease activity 0.30 (75%) attained CR on therapy with ≥3 doses of RTX 500 mg (MD= 76.39±34.45 days) and azathioprine 100 mg/day. No patients relapsed after 4 doses while 3 (7.5%) patients didn't respond. Oral lesions and pemphigus vulgaris took more time for achieving CR. Conclusion: While we reinforce the idea of using more than 3 doses of RTX 500 mg in a view to achieve prolonged remission we promote considering usage of a more cost-effective drug like azathioprine for maintaining remission especially in a poor remote tertiary center in India with limited resources. Immunological assays were not performed limiting the study.


ABSTRACT This is a progress report for a project attempting to gather and share information about effective dropout prevention strategies in action at the middle school and high school levels around the Northwest region of the United States. Introductory material reviews current views of the dropout problem, recent reports which address the issue of high-risk youth from a national perspective, and characteristics of high-risk youth. The bulk of this report focuses on identifying characteristics of effective practices for this population of potential dropouts. A literature review shows that there is no widely accepted set of evaluation criteria for judging the effectiveness of specific strategies. The paper discusses the work of Gary Wehlage and other researchers to reduce school attrition, state and city school districts' dropout prevention program characteristics, and regional efforts. Also described are the findings from a questionnaire sent to administrators to identify successful programs their schools have used with high-risk youth. The effective programs share the following common characteristics. (1) a qualified, caring staff; (2) a relevant, meaningful curriculum based on real-life experiences and goals; (3) individualized instruction with low student/teacher ratio; and (4) the support and commitment of administrators. This list of successful program characteristics will be refined and incorporated into a checklist of strategies and related outcomes that are common to programs serving at-risk youth. A bibliography and copy of the questionnaire are included. (AIM)


The invention discloses a medicine dispensing process of a ground sorting type intelligent medicine dispensing control system. A medicine dispensing machine sends out medicine, the medicine falls into first conveying devices arranged at the bottom through a buffer device, and then the medicine enters to a second conveying device. When the medicine enters to the second conveying device, a basket with bottom up is sent to the tail end of the second conveying device from a basket sending device, and reaches a lifting platform of a hoister before the medicine reaches the lifting platform, each basket is provided with a radio frequency identification chip, and a radio frequency identification device is arranged at the position, corresponding to each basket, of the bottom of the hoister. When the lifting platform rises to the upper end of the hoister, a control terminal gives an order, a basket pushing device pushes baskets which contain medicine of unfinished prescriptions to sorting platforms at the left end and the right end, sorting of alien-packed medicine continues until the prescriptions are accomplished, or the basket pushing device pushes baskets which contain medicine of finished prescriptions to a medicine dispensing platform. According to the technical scheme, the medicine dispensing process of the ground sorting type intelligent medicine dispensing control system is high in working efficiency, systematic, and capable of accurately and rapidly carrying out medicine dispensing.


| X (t) dt = f(cx)(x-a). (2) Jacobson studied the behavior of cx as x approaches a, and proved the following result: Theorem 2. Suppose the function f is continuous on t1te interval [a, b] and is differentiable at a with f'(a) + O. If cx is given in the mean value formula (2) for integrals, then c -a 1 li x =_ (3) xoa X-a 2 We consider the case f '(a) = O in Theorem 2. Theorem 3. Suppose the function f is continuous on the interval [a,b] and is twice-differentiable at a with f'(a) = O, f"(a) + O. If cx is given in the mean value formula (2) for integrals, then


Background: Research indicates that regular physical activity is associated with numerous physiological and psychological health benefits for childhood cancer survivors. A review of the literature reveals that no study has so far examined the physical activity levels and behavior of Hong Kong Chinese childhood cancer survivors, and how the cancer and its treatment affect the physical activity and other behavior of these children remains unclear. Objective: The aims of this study were to assess the physical activity levels of Hong Kong Chinese childhood cancer survivors and to explorethe factors that affect their adherence to and maintenance of regular physical activity. Methods: A cross-sectional study was used. A total of 128 childhood cancer survivors (9Y16-year-olds) who underwent medical follow-up in the outpatient clinic were invited to participate in the study. Results: There was a significant decline in physical activity levels among childhood cancer survivors. Most of them did not take physical exercise regularly. Concern about academic performance, fatigue, and a decrease in physical strength and endurance after remission prevented them from engaging in regular physical activity. Conclusions: This study indicates that many childhood cancer survivors did not engage in regular physical activity and that they overlooked or underestimated its importance. Implications for Practice: It is essential for nurses to correct misconceptions about physical activity among childhood cancer survivors and


Trichloroethylene (TCE) induced occupational medicamentosa-like dermatitis (OMDT) is a systemic skin disorder accompanied by liver dysfunction in workers occupationally exposed to TCE. The present study employed massive parallel sequencing by AluScan developed by us to determine genetic variations associated with sensitivity to TCE exposure. With coverage of 14.54 Mb genome regions with at least four-fold depth across two OMDT patients and two control subjects, singlenucleotide polymorphism (SNP) rs941960 located in the CCBL1 gene coding for cysteine conjugate-beta lyase, and copy number gains in CYP2C9 and CYP3A4 were identified as plausible causal factors of OMDT, all of which are components of TCE metabolic pathways. These results ascertained that variants of these genes could increase the concentrations of metabolic intermediates of TCE that may act as antigens to trigger abnormal immunological responses and give rise to liver dysfunction. Correspondence to: Hong Xue, Division of Life Science, Hong Kong University of Science and Technology, Clear Water bay, Hong Kong, Tel: (852) 23588707; E-mail: email@example.com Xinyun Xu, Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong 518055, China, Tel: (086) 755-25609527; E-mail: email@example.com


On 17 June 2020, a large ancient landslide over the Aniangzhai (ANZ) slope, Danba County, Sichuan Province, China, was reactivated by a series of multiple phenomena, including debris flow triggered by heavy rainfall and flooding. In this study, Synthetic Aperture Radar (SAR) images acquired by the Sentinel-1A/B satellite and optical images captured by the PlanetScope satellites were jointly used to analyze and explore the deformation characteristics and the Spatial-Temporal evolution of the ANZ landslide before and after the multi-hazard chain. Several areas of pre-failure movements were found from the multi-temporal optical images analysis before the reactivation of the ANZ landslide. The large post-failure surface deformation over the ANZ slope was also retrieved by the optical pixel offset tracking (POT) technique. A major northwest movement with the maximum horizontal deformation of up to 14.4 m was found. A time-series InSAR technique was applied to analyze the descending and ascending Sentinel-1A/B datasets spanning from March 2018 to July 2020, showing that the maximum magnitudes of the Line of Sight (LoS) displacement velocities were −70 mm/year and 45 mm/year, respectively. The Spatial-Temporal evolution over the ANZ landslide was analyzed based on the time-series results. No obvious change in acceleration (precursory deformation) was detected before the multi-hazard chain, while clear accelerated deformation can be observed over the slope after the event. This suggested that heavy rainfall was the most significant triggering factor for the generation and reactivation of the ANZ landslide. Other preparatory factors, including the deformation behavior, the undercutting and erosion of the river and the outburst flood, the local terrain conditions, and earthquakes, might also have played an important role in the generation and reactivation of the landslide.


Functional dyspepsia is a highly prevalent condition in the general population. Many allopathic and herbal therapies have been tried but with limited success ...


ifteen multiparous Friesian cows with live body weight (LBW) of 510-532 kg and 2-4 parities were used at 45 days pre-partum and continues until 120 days post-partum and divided into three similar groups (5 in each group) for study the effect of Spirulina additive on their productive and reproductive performance. Group 1 was unsupplemented which was served as control (G 1 ), or supplemented with Spirulina and their media at the levels of 1 ml (low level) or 2 ml (high level) / kg LBW in drinking water for tested treatments G 2 and G 3 , respectively. Spirulina was grown in a modified Zarrouk , s medium for 21 days. Results showed that digestibility of all nutrients and feeding values of G3 were significant higher (P<0.05) than those of either of G1 or G2, and also all values of these items were significant higher than those of G1. Total DMI was insignificant increased with G2 and significant increased with G3 compared with that of G1. Ruminal pH values did not significant affected by treatments, while TVFA's was increased significantly with increasing Spirulina supplement in dietary treatments and NH 3 -N values had an inverse trend among treatments. Most blood biochemical and haematological parameters were markedly increased with increasing the algae level in drinking water of cows. Live body weight and body condition score decreased gradually until reach 90, 75 and 60 days and increased thereafter for G 1 , G 2 and G 3, respectively. Group 3 recorded significantly (P<0.05) the highest daily yield of actual milk and 4%-FCM, colostrum and milk composition, feed and economic efficiencies and the lowest electrical conductivity in milk. Concerning reproductive traits, cows in G 3 recorded significantly (P<0.05) the short periods from parturition until the first estrus and insemination, as well as days open, the highest conception rate and the lowest number of service per conception. In conclusion, cows supplemented with Spirulina and their media at the level of 2 ml/kg LBW in drinking water showed the best results concerning productive performance and body condition score as well as post-partum reproductive traits.


Summary In the summer of 2018 on the boundary of the Laptev Sea and Arctic Ocean, JSC SMNG and OP SPbMP JSC Rosgeologia performed integrated regional geophysical investigations including 6000 line km of 2D CDP seismic reflection data, above-water gravimetric and hydromagnetic data. From the seismic data, a tectonic map for the base of the sedimentary cover was constructed. On this map, boundaries of Priseverozemelsko-Pritaymyrskaya continental margin and Eurasian oceanic basin were refined, West Laptev continental slope and Progradational Area of the Gakkel Ridge studied for the first time. From data of gravimetric and magnitometric surveys, a map of classes of magnetic and gravity fields anomalies corresponding to the blocks of rocks with different physical properties was calculated. Integrated analysis of geophysical data enabled to compare the positions of the boundaries of the Pritaymyrsko-Prinovozemelskaya contintntal margin and the Eurasian oceanic basin and reveal basement blocks with different physical properties.


Introduced the octonion basic properties,has produced the equation in the octonion complete solution,and discussed the solution and the coefficient relations.


Characteristics of macroelements in granite in Yunwuling area is high-K calc-alkaline metaluminous to weakly peraluminous "A Type" granite, which was generated by early to metaphase (Jurassic) magmatism among the Baryan Har Terrain ascending.Based on the tectonic setting discrimination, the rock is "POG type" granite, which was generated by the crust transforming from post orogenesis phase to intraplate phase.


The lean years Fred described 1955–64 as his 'lean years' as he published relatively little then. In fact, this was a transitional period in which Fred was exploring completely new ideas for sequencing proteins. His idea was to radioactively label proteins. After radioactively labelling a protein and then isolating a radioactive peptide, he would work out the sequence around the labelled amino acid, indirectly. For example, he would use various modifications of the peptide, e.g. removal of the N-terminal amino acid, and monitor changes in the mobility of the peptide on paper chromatography or paper electrophoresis. He was using the position of the peptide as a way of sequencing. This new way of thinking would, in principle, have many advantages. It would not require as much protein as his classical procedures worked out on insulin, since radioactively labelled peptides would be easily and quickly detected on paper by the then relatively new and sensitive method of autoradiography – using an X-ray film. The protein would not necessarily have to be pure, as long as it was radiochemically pure. For example in 1958 Fred incubated an isolated oviduct from a hen with 1 mCi 32 P-labelled inorganic phosphate. He successfully isolated 32 P-labelled ovalbumin, which was known then to contain two serine phosphates. Fred correctly deduced the presence of one phosphate-containing dipeptide, as serine phosphate-alanine, an observation confirmed ten years later by classical methods of peptide sequencing. Twenty years later on in 1978, in a very different era of DNA sequencing, my colleagues and I showed the exact position of this dipeptide in ovalbumin, as deduced from the nucleotide sequence of a cDNA clone of ovalbumin mRNA.


Objective
To study the non-fermenter isolation rate and its drug resistance to more than 10 kinds of antibiotics at the First Affiliated Hospital to Xinxiang Medical University from the year of 2010 to 2012 in order to offer evidences for reasonable use of drugs by doctors and to prevent nonfermenters from becoming common pathogenic bacteria.

Methods
The infection and drug resistance of different Nonfermenters (Pseudomonas aeruginosa, Acinetobacter baumannii, Pseudomonas maltophilia, Los non Acinetobacter, Pseudomonas stutzeri, Achromobacter, Bacillus steady short, onions Bock cepacia, meningitis septicemia Elizabeth Kim bacteria)during present 3 years were analyzed by using WHONET 5.5 software.

Results
The infection rate from non-fermenters as pathogenic bacteria was gradually increased, with the rate from 18.2% to 27.2%, until 31.2%; Acinetobacter Baumannii were isolated as higher infection rate and multiple drug resistance (7.1% to 18.5% until 28.7%) in pathogenic bacteria; the infection rate of other non-fermenter with infection rate of high and multiple drug resistance in pathogenic bacteria were gradually increased, such as infection rate or the precedence of Achromobacter xylosoxidans and Pseudomonas maltophilia, especially the precedence of Pseudomonas maltophilia ranged the third in non-fermenters, and Pseudomonas maltophiliai had a higher and multiple drug resistance to many antibiotics; infection rate of non-fermenters with low drug resistance gra-dually decreased, such as Pseudomonas fluorescens; the drug resistance rate of Acinetobacter Baumannii was higher than that of Pseudomonas aeruginosa and its drug resistance rate was over 50% to common antibiotics used clinically, as well as Pseudomonas maltophiliai and Empedobacter brevis, especially the resistance rate of Pseudomonas maltophi-liai to many commonly used antibiotics was more than 90.0%.

Conclusions
Non-fermenter isolation rate is becoming higher clinically and its drug resistance becomes more severe, so the sanitation administration department should pay more attention to the use of antibiotics in order to prevent and control drug resistance and higher infection rate caused by non-fermenters as a serious consequence.

Key words:
Non-fermenter; Drug resistance; Infection frequence; Antibiotics


Introduction Biodegradable polymers that contain radioactive isotopes such as Holmium 166 have potential applications as beta particle emitters in tumor tissues. Also, Ho(III) is paramagnetic, which makes it suitable as a contrast agent for magnetic resonance (MR) images. Methods Holmium acetylacetonate (Ho(acac)3) loaded poly(3-hydroxy-butyrate-co-3-hydroxy-valerate) microspheres, with 5% or 8% of 3-hydroxy-valerate (HV), were prepared by emulsification/evaporation process within 20–53 μm size. Microspheres characterization was done using scanning electron microscopy, energy-dispersive X-ray, and infrared spectroscopies. The release of holmium(III) in sodium phosphate buffer (pH 7.4) was followed for 9 days with inductively coupled plasma. Finally, T2 and T2* magnetic resonance images (MRI) were acquired and compared with the MRI of the inclusion complex of holmium acetylacetonate in some β-cyclodextrins. Results Holmium acetylacetonate loading, evaluated by thermogravimetry, was up to 20 times higher for copolymer with 5% of HV. It was shown that microspheres loaded with Ho(acac)3 exhibited an accumulation of Ho(III) on their surfaces but were stable over time, as no expressive release of holmium(III) was detected in 9-day exposition to sodium phosphate buffer. Holmium acetylacetonate in both microspheres or inclusion complexes was very efficient in obtaining T2 and T2* weighted images in magnetic resonance, thus, might be used as contrast agents. Conclusion This is the first description of the use of inclusion complexes of holmium acetylacetonate in biodegradable polymers as contrast agents. New investigations are underway to evaluate the resistance of PHB-HV polymer microparticles to nuclear activation to assess their potential for use as radiopharmaceuticals for the treatment of liver cancer.


L-proline catalyzed Michael additions of 1-aryl-3-methylenpyrrolidine-2,5-diones to 4-phenylbut-3-en-2--one in MeOH are examined to obtain 1-aryl-3-methyl-4-(3-oxo-1-phenylbutyl)pyrrole-2,5-diones in moderate yields. The L-proline forms with the α,β-unsaturated ketone the reactive iminium intermediate which as an acceptor reacts with a complex formed between the amine and the enolate, giving enamine.