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Use this link when booking for the donation to come to WK
Many thanks to all those who are continuously using Booking.com whenever they are travelling. UWC Adriatic alumnus Darren Huston (AD 83-85), ex-CEO of Booking.com, generously offered to help fundraise for Waterford Kamhlaba UWCSA through the Booking.com website. On a visit to UWC Adriatic in 2014, Darren was struck by how many of the students and alumni of the 16 UWC colleges are frequent travellers. This gave him the idea to create a way for alumni, supporters and friends of the college to donate simply by using Booking.com.
Booking.com generously agreed that a percentage of the booking fee will be donated to Waterford Kamhlaba UWCSA. All of the money raised will go into a grant to help us offer another student a scholarship here at Waterford Kamhlaba UWCSA. Remember to use Booking.com during the festive season. Use this link when booking and share with friends and family to get as many people involved as possible.


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Let's be clear here: This is largely a thought experiment. Republicans have plenty of things going for them in the 2014 midterms. There's no historical precedent for the president's party to take over the House from the other party in a midterm; indeed, history tells us that the "out" presidential party — in this case, the GOP — is likelier to gain seats than the "in" party. The president's approval rating as measured by the HuffPost Pollster average is actually worse today — 43.4% approve, 51.0% disapprove — than it was right before the 2010 midterm (45.1% approve, 49.9% disapprove). As we've shown recently — and as Prof. Arrington's piece indicates — Democrats are going to have to really dominate the House generic ballot, and Election Day national House vote margin, to have a real chance at taking back the House. However, if Republicans do open the door to the Democrats in the House, it's not going to be the "Ted Cruz Republicans" who will pay the price. Rather, it's the House Republicans in marginal districts who could see their ranks decimated, just like the House Democratic moderates whose anti-Obamacare votes couldn't save them in 2010.
"We started this on a fool's errand, convincing so many millions of Americans and our supporters that we could defund Obamacare," McCain said.While McCain didn't name names, he faulted members of Congress -- "tea partiers specifically" -- for wrongly telling "millions of Americans" that Obamacare can be defunded.That "obviously wouldn't happen until we had 67 Republican senators to override a presidential veto," McCain said.
They complained that people were speaking of Obamacare but I did see a deep distinctive difference between how long you've been here or not or what's too conservative or liberal. If you went home and actually conducted town halls in August, you got a message, because people care about it. And I think Washington likes to deride these views as tea party and it's a minority, but the clear majority of the Republican Party 80 to 90 percent is saying, 'We don't want Obamacare.' John Boehner said that. I put out a statement saying, 'I hope you hold firm to that.' John Boehner said, 'They don't want a government shut down and they don't want Obamacare and the rumors are there about ready to give up stopping Obamacare and then open the government back up. I think we can do both principles at once.'"

subset: commoncrawl


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How-toThanks to a secret ingredient, artist-chef Lexie Smith's version of the quintessential breakfast dish is sure to be the most addictive you've ever had.
How-toThis smooth avocado-cucumber gazpacho from artist-baker Lexie Smith, is spiked with aromatic green herbs, garlic, and a handful of raw ginger—and comes together in a blender in mere minutes.
How-toArtist and baker Lexie Smith shares a recipe for a Malaysian-inspired roti that looks as great as it tastes.
BeautyAs Vogue celebrates its 125th year, we look back at the history of fashion, and the magazine, in a series of "five points" videos by decade, narrated by the stylish Sarah Jessica Parker. In the above episode, we take a look back at the roaring '20s.
BeautyAluna Francis, singer of British duo AlunaGeorge, has fast become one of music's most intriguing beauty chameleons. Here, she reveals the tricks behind her go-to look, from her expert cat-eye technique to her secret hairstyling weapon.
BeautyNo matter how breakneck Gwyneth Paltrow's day is, her foolproof beauty routine can take her from the office to the party in a matter of minutes. From the secret to youthful skin, to a toxin-free bold red lip and an all natural fragrance that leaves her smelling smarter, watch how the actress cum wellness guru stays perennially fresh faced.
BeautyAs a top model and social media powerhouse, Ashley Graham spends a great deal of time flitting from one glamorous event to the next. Here, she breaks down her secret to easy red carpet beauty, from a dewy cheek blush to loads of iridescent highlighter.
Filmed at the Four Seasons Hotel New York Downtown, fourseasons.com/newyorkdowntown/
BeautySuki Waterhouse is the It Brit model and actress with an entirely loose, on-the-fly approach to makeup. Here, she breaks down her morning beauty routine, including the secret to her perfectly smudged cat-eye.
Filmed at the Plaza, New York
BeautyCiara may be an otherworldly beauty with a career in the stratosphere, but in at least one respect, she's just like any other woman: She often has to squeeze in a quick touch-up between a full-throttle workday and a big night out.
BeautyModel Grace Hartzel shares the steps to creating a Halloween homage to David Bowie's iconic beauty look from "Life on Mars?" video.
Jill Stuart Cemile halter metallic knit, $228
For information: jillstuart.com
Filmed at the Standard High Line, New York
BeautyLolita fashion is one of Japan's most iconic subcultures, instantly recognized by its whimsical take on period style, and on a recent trip to Tokyo, Sofía Sanchez de Betak stopped by Maison de Julietta for a complete ama-loli makeover. Here, watch De Betak's beauty transformation, from rosy circles of blush to a doll-like pink wig.
BeautyThe Oklahoma City Thunder point guard is a front row fixture at the shows. Here, his 5 tips for an all-star New York Fashion Week.
How-toA simple egg sandwich never looked so good. Chef Jessica Koslow of Sqirl shows us how to make the perfect breakfast sandwich in just a few easy steps.
BeautyWunderkind director Xavier Dolan, 27, took home the Grand Prix at the 2016 Cannes Film Festival this past weekend. Dolan, known for directing Adele's video for "Hello" and starring in Louis Vuitton campaigns, took a minute from his back-to-back Cannes schedule to talk to Vogue.com about why he doesn't differentiate between high and pop culture.


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Private Party Car Exchange came to us looking for a website fast! We went to work the same day we got their call and finished this website within the week (our record). It doesn't have much "text" content – instead the challenge was integrating an inventory function to display recently sold cars and cars available for purchase. We also included an inventory search feature so clients can easily browse for the car of their dreams!
Logo Design, SEO, Social Media, Website Design
"Huge thanks to The Gorilla Agency. You were a pleasure to work with and you did an amazing job - so thank you!"


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My first set with BoldDaniel just went live and I think it is my favorite from the 1st session we did, hopefully you will like it and want to see more... (read more)fredacat BrooklynRick
Hi, I hope you have a good start to the week, I invite you to see my work and know your opinion.Nuitari BrooklynRick
hi honey, soon it's Christmas, I hope you have happy holidays, I leave the link to my new set, enjoy... xxxxxxxxxxxxNuitari BrooklynRick
Thanks for the FR :) Here's my the newest set https://www.zivity.com/models/LenArt/photosets/2 . As always I have very hot bonus shoots for You!LenArt BrooklynRick
Thanks so much for the add! I just had a new set go up, take a look: https://www.zivity.com/models/CaitlinMichele/photosets/11 xoCaitlinMichele BrooklynRick
Yay new photo friends!StoneNYC BrooklynRick
Thanks for being my friend.KelsJae BrooklynRick
Check out my first prize entry and let me know if you think I've got what it takes.
Check out my first prize entry and let me know if you think I've got what it takes.
Thanks for the add <3(deleted) AngelEyez BrooklynRick
Hi, check out my new dark, sexy set for the Rob Zombie contest. I hope you like it!!! ;-)(deleted) HellKitty BrooklynRick
Hi, thanks for accepting my fr!Kealani BrooklynRick
Ok, here it is. My entry into the Commando contest, Panty Dropper. I just got home from shopping for new outfits and props for my sexiest bonus video and self shot set yet which I'm shooting tonight... (read more)Gwendolyn BrooklynRick
Yay! A prize totally dedicated to tattoos! What better chance for me to show off mine. Come check out Tits & Tats and don't forget to throw your 10 votes in to get super sexy bonus photos featuring my... (read more)Gwendolyn BrooklynRick
Making a famine where abundance lies
New set by RoPo & BrooklynRick
And my delight is causer
New set by Vyl8 & BrooklynRick
As soon as I saw the Stripes contest I knew I was going to get down and dirty on my Zebra rug. Come check out my new set, My Zebra Rug! 10 votes gets all bonus photos. 20 gets bonus photos from 3 sets... (read more)Gwendolyn BrooklynRick
Come explore my darker side in my latest featured set, Fetish Couture, which is entered in the Fetish prize. 10 votes gets all bonus photos. 20 gets bonus photos from 3 sets of your choice. 30 gets... (read more)Gwendolyn BrooklynRick
My new featured set, Cupid's Bow is in the Valentine's Day contest. 20 votes gets all bonus photos from 3 sets of y our choosing and 30 votes gets a 51 photo self shot set never to be published on... (read more)Gwendolyn BrooklynRick
Hey you! I invite you to come check out my newest set Dangerous Curves Ahead. It's in the But Sir contest and a really cool homage to my ass! lolGwendolyn BrooklynRick
10 votes gets all bonus photos.
20 gets bonus... (read more)
10 votes gets all bonus photos.
20 gets bonus... (read more)
Just wandering around zivity letting everyone know about my newest set, Greasy Grimy Girl. I had tons of fun in my bathtub, especially with the running water ;), but you can only see the 10 bonus... (read more)Gwendolyn BrooklynRick
Happy HolidaysAlycHope BrooklynRick
Thanks for being friends! If you like curvy redheads all oiled up, give a look at my latest: http://www.zivity.com/models/ArielVonVargas/photosets/19ArielVonVargas BrooklynRick
Have I been naughty or nice this year? Well why don't you come find out! 10 votes gets all the bonus images and 25 gets you a video. Then you can be the judge ;)... (read more)Gwendolyn BrooklynRick
I love latex! If you do too, come check out Blue Latex. It's entered in the Fully Clothed prize. Given the nature of the prize I couldn't publish any nudes but just 1 vote plus a comment will get you... (read more)Gwendolyn BrooklynRick
hey darling how are you latelyAlycHope BrooklynRick
Miss (Speak No) Evil is up in the Top Photography contest. I really love this set and we worked super hard on it. I'd like to see it get 1000 votes so check my wall for super hot incentives... (read more)Gwendolyn BrooklynRick
My new set 'The Backseat' is up by AftermathPhoto!Guns BrooklynRick
The bonus pictures are just as good!
Check it out! Vote if you like!
The bonus pictures are just as good!
Check it out! Vote if you like!
Which Doubles Payne
New set by RoPo & BrooklynRick
Hi! Thanks for being my friend! I'm a new zivity model and I'd love for you to check out my first set.(deleted) ForesTofgotham BrooklynRick


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Prevent your kids from becoming A Gadget Addict
Is your child a Phone or Ipad addict..?
Admit it… Most of our kids Play-Grounds are virtual than Real… We cannot deny the fact that they are getting addicted to the electronic gadgets.
It has become a very common problem with many new parents these days. Technology is very informative and entertaining for sure, but it has equal health effects on our child. Their Eating habits.. Sleep time.. Play time.. we may have to compromise on everything if they become too dependent on these gadgets.
If you are looking to 'DIGITALLY DETOX' your child.. These few things may help you…
NO TV/ IPad AT MEAL TIME :
We want our children to eat no matter what. So, the easy way is to engage them in watching something and make them eat. Sometimes they don't even know what they are eating.. For them its simple.. Meal time = TV Time.. This is the first change we need to make..
Being practical, we cannot expect our little ones to sit on a dining table and eat silently.. So, instead of putting gadgets before them.. Engage them in some arts n crafts.. Like Play-Doh.. Books with Big Pictures.. Number Blocks.. Etc.. For older kids story telling is the best solution..
It may look like something really impossible.. But there is every possibility to alteast restrict the TV/Ipad watching time..
Figure out a weekend activity.. Cycling is a good physical activity.. It will be so much fun and kids will look forward to it every week. This way, we can spend more time with our kids too.. This is a real good way to diverting our kids to real playground rather than playing games in Phone and I pad.
Proper sleep is very important for the overall development of children.To develop a Proper sleeping routine it should be made a rule not to carry Any electronic devices to the bed. Initially kids may show a lot of resistance, but gradually they will develop the habit to sleep without a Phone or IPad.
Read them a story book every night.. This will be best habit we can cultivate for our child for his life.
Our kids get habituated to gadgets only because of boredom. Take them for a little walk everyday.. They will love to observe things happening around.. They will develop ways to think and understand everything practically. This will help them make new friends.
Also, walking will physically tire them out and they will be super hungry.. It will be very easy to feed them and put them to sleep on the go.
Set time for meals.. Set time to play with toys.. Set a time to watch T.V or IPad.. Set a time for everything.. It may take sometime to adjust, but be strict about this.. Even on weekends and holidays…This will help them develop discipline and help them achieve big things as they grow up.
This is a very important aspect. As parents we are overloaded with work and don't find quality time to spend with our kids and we try to divert them by giving gadgets to get things going. Overtime they get addicted to them and we regret it. We can avoid this by spending some time with kids.
It may be a very little time.. Take turns with your partner, but spend some time with them..
Always remember – Our kids are our future.. Our child needs US.. A Gadget cannot replace US.


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But maybe the thing that we as librarians don't always realize or notice, is the impact that we have on your lives. Some days it's easy to forget in the hustle and bustle of the library that we are playing a part in your lives too. That this job impacts so many lives in so many ways. Never does this become more apparent than when we lose one of our patrons. I have been in the library field for 12 years now and have lost some very beloved patrons over the course of that time. Each time, I am reminded of the daily impact that I can have on someone's life. The role that I play, each day, in helping someone or sometimes just being a friendly smile. It is important. Sometimes more than I could ever know.
"A life is not important except in the impact it has on other lives." -Jackie Robinson


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Watch The Jerry Sandusky Smoking Gun Video That NBC Deleted bit.ly/MqEpZf
SbB has learned Chris Broussard & Jon Barry won't returm to ESPN's NBA studio. Added to show: @sportsguy33 & Stan Van Gundy
Got a friend still on the fence about Paterno statue? They won't be after you send them this: bit.ly/O2WQCj
Sandusky now facing 529 years in prison + $825,000 in fines for heinous crimes - and is at trial - and hasnt spent one second in custody.
Penn State: Your school will forever be stained with the blood of innocent children. We will never forget. Never.
Jerry Sandusky is a very sick man. Photo taken today. (via @OnwardState) bit.ly/OLjK3W
Jerry Sandusky mugshot / booking photo: bit.ly/LHCvlQ


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Authors: Sidharth Ghoshal
We write a solution for solving all equations of the type a(x)f(x+h) + b(x)f(x) + c(x)f(x)^2 = 0 And use this to create a variety of formula for infinite nested radicals
Comments: 10 Pages.
Download: PDF
[v1] 2015-03-23 23:22:06
Unique-IP document downloads: 71 times
Add your own feedback and questions here:
You are equally welcome to be positive or negative about any paper but please be polite. If you are being critical you must mention at least one specific error, otherwise your comment will be deleted as unhelpful.


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Nigerian gay rights activist, Bisi Alimi, has shared new photos of his Alter Ego, Ms Posh Pussy on Instagram.
He captioned one of the photos:'Because every lady needs a hat to break a heart'. LOL! See the photos below:
PAY ATTENTION: Get all the latest gossips on NAIJ Gossip App
Mr Bisi Alimi was recently at the UK registry with his husband-to-be to give notice for their wedding which coming up in November.
Source: Gossip.naija.ng


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Traveling Luck for Camp Ya-Ho-Le, Florida, United States
Where is Camp Ya-Ho-Le?What's around Camp Ya-Ho-Le?
Wikipedia near Camp Ya-Ho-Le
Where to stay near Camp Ya-Ho-Le
The timezone in Camp Ya-Ho-Le is America/Iqaluit
Sunrise at 07:57 and Sunset at 18:30. It's Dark
Latitude. 29.5264°, Longitude. -81.9517° , Elevation. 27m
Weather near Camp Ya-Ho-Le; Report from Gainesville, Gainesville Regional Airport, FL 47.7km away
Weather :
Temperature: 17°C / 63°F
Wind: 8.1km/h Northeast
Cloud: Scattered at 700ft Broken at 2500ft
Weather :
Temperature: 17°C / 63°F
Wind: 8.1km/h Northeast
Cloud: Scattered at 700ft Broken at 2500ft
Satellite map around Camp Ya-Ho-Le
Loading map of Camp Ya-Ho-Le and it's surroudings
Geographic features & Photographs around Camp Ya-Ho-Le, in Florida, United States
- lake;
- a large inland body of standing water.
- Hankley Lake (2.3km)
- McCarthy Lake (2.6km)
- Key Pond (3.1km)
- Brim Pond (3.4km)
- Picnic Lake (3.6km)
- Skinner Lake (3.6km)
- Bull Pond (3.8km)
- Hewitt Lakes (4.3km)
- Higginbotham Lake (5.5km)
- Susan, Lake (5.5km)
- Deer Back Lake (6.4km)
- Fanny, Lake (6.5km)
- Horseshoe Lake (6.6km)
- Issue, Lake (7.2km)
- Gillis Pond (7.3km)
- Island Lake (7.9km)
- Darkwater Lake (8.6km)
- Ox Pond (9.1km)
- Pegram Lake (9.4km)
- Bay Lake (10km)
- Redwater Lake (10.1km)
- Riley Lake (10.6km)
- Blue Lake (10.6km)
- Star Lake (11km)
- Stokes Lake (11.3km)
- Dozier Lake (11.5km)
- Green Pond (11.6km)
- Blue Pond (11.6km)
- Bully Lake (11.8km)
- McMeekin Lake (11.9km)
- populated place;
- a city, town, village, or other agglomeration of buildings where people live and work.
- Orange Springs (3.1km)
- Fort Brook Landing (5.9km)
- Lands End Ranch (6.8km)
- Hog Valley (8.7km)
- Johnson (9km)
- Edgar (10.1km)
- Crossley (10.7km)
- Bay Lake (12.3km)
- Local Feature;
- A Nearby feature worthy of being marked on a map..
- Camp Ya-Ho-Le (0km)
- Camp Horizon (1.5km)
- Camp Katori (2.5km)
- Hickory Camp (8.1km)
- Cracker Landing (10.5km)
- Paynes Landing (historical) (11.3km)
- Cedar Landing (11.3km)
- Gordon Chapel (12.2km)
- church;
- a building for public Christian worship.
- Bethel Church (4.3km)
- Orange Springs Church (7km)
- Woodlawn Church (9.1km)
- Edgar Community Church (9.4km)
- Mount Bethel Church (12.5km)
- stream;
- a body of running water moving to a lower level in a channel on land.
- Little Orange Creek (2.5km)
- Cabbage Creek (2.9km)
- Orange Creek (5.3km)
- Gum Creek (12.4km)
Accommodation around Camp Ya-Ho-Le
- spring(s);
- a place where ground water flows naturally out of the ground.
- Blue Springs (12.4km)
- airport;
- a place where aircraft regularly land and take off, with runways, navigational aids, and major facilities for the commercial handling of passengers and cargo.
- 85th Avenue Airstrip (11km)
- reservoir(s);
- an artificial pond or lake.
- Lake Ocklawaha (5.3km)
- school;
- building(s) where instruction in one or more branches of knowledge takes place.
- Oak Grove School (12.3km)
- tower;
- a high conspicuous structure, typically much higher than its diameter.
- WWAK-AM (Redwater Lake) (8.4km)
- cemetery;
- a burial place or ground.
- Drummond Cemetery (9.9km)
Wikipedia entries close to
Camp Ya-Ho-Le
- Orange Springs, Florida city o
- Interlachen, Florida city city o
- Hawthorne (Florida) city city m
- Hollister, Florida city o
- Fort McCoy, Florida city o
- Citra, Florida city o
- Cross Creek, Florida city o
- Grandin, Florida city o
- Putnam Hall, Florida city o
- Florahome, Florida city o
- Gainesville-Hawthorne Trail State Park city city o
- Sparr, Florida city o
- Windsor, Florida city o
- Rochelle, Florida historical c
- McIntosh, Florida city o
- Welaka, Florida city city o
Airports close to Camp Ya-Ho-Le
Gainesville rgnl(GNV), Gainesville, Usa (47.7km)
Cecil fld(NZC), Jacksonville, Usa (102.2km)
Jacksonville nas(NIP), Jacksonville, Usa (109.9km)
Jacksonville international(JAX), Jacksonville, Usa (146km)
Executive(ORL), Orlando, Usa (166.3km)


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Queen Creek Performing Arts Center has announced the cast of "Shrek, the Musical."
More than 240 people tried out during the auditions, which took place April 13-15, at the performing arts center, 22149 E. Ocotillo Road in Queen Creek. In the end, 54 main cast members and 27 children were cast.
QCPAC staff members urged auditioners who were not selected to not be discouraged.
"Please remember, whether you make it or not, if this is your dream or you enjoy theater, don't stop. The QCPAC has over 240 auditionees and we only cast 54 in the main cast and 27 kids. That means a huge number of people didn't get in this show. It is heartbreaking to cut so many talented and wonderful people, but there will be other shows. To the auditionees who made the cast of "Shrek," please take full advantage of the journey ahead because many would like to be on your path. I'm a believer!," a staff member messaged on the audition news page of the QCPAC website: www.qcpac.com.
"Shrek" will be performed June 23-24 and 26. Show times are 7 p.m. Friday, June 23; 2 p.m. and 7 p.m. Saturday, June 24; and 7 p.m. Monday, June 26. Tickets cost $15 for adults and $13 for children. They may be purchased on the QCPAC website or by calling the box office at 480-987-7469.
The cast list is as follows:
Shrek: Jacody Bullard
Fiona: Danica Hill
Donkey: AJ Thompson
Lord Farquaad: Andy Newman
Dragon: Brittany Thomas
Gingy, Sugar Plum Fairy and Young Fiona: Xandra Gunnell
Young Fiona: Madelynn Atkinson
Pinocchio: Caden Marshall
Wicked Witch: Beth Benning
Humpty Dumpty: Christian Tarin
Elf/Three Blind Mice: Isabelle Wisdom
Ugly Duckling/Three Blind Mice: Caitlyn Mckell
Mama Bear/Three Blind Mice: Janna Hanson
Papa Bear: Tyler Allen
Baby Bear: Kailyn Scott
Pied Piper: Jeremy Allen
Fairy Godmother: Mandy Clegg
Big Bad Wolf: Noah Lumley
White Rabbit: Ravyn Bullard
Peter Pan: Rhett Smith
Blue Bird/Jill: Lydia Atkinson
Papa Shrek/Greeter: Kelly Jarman
Mama Shrek: Tina Reynolds
Madhatter: Andrew Nickle
Piggy 1: Montana Ludlow
Piggy 2: Cedar Shirley
Piggy 3: Sarah Atkinson
Ugly Stepsister: Christyn Polk
Ugly Stepsister: Rhea Johnston
Queen: Amie Ford
Prince Charming: Gabriele Peck
Little Red Reding Hood:Ke'arah Masten
Magic Mirror/Ensemble: Matt Snell
Captain of the Guards: Trey Ervans
Thelonius/Bishop/ Duloc Announcer: Jason Abney
Guard (main) Knight: Brady Anderson
Guard/Knight 1: Stephen Smith
Guard/knight 2: Jake Brabender
Guard/Knight 3: Kyle Atkinson
Guard/knight 4: Duncan Goodman
Guard/Knight 5: Dalin Smith
Duloc dancer/Mob: Alyssa Jeffs
Duloc dancer/Mob:Alyssa O'Brien
Duloc dancer/Mob: Autumn Eggers
Duloc dancer/Mob: Lori Carter
Duloc dancer/Mob: Michelle Capriotti
Duloc dancer/Mob: Tapanga Ludlow
Magic Mirror/Ensemble: Matt Snell
Ensemble: Kimberly Atkinson, Michelle Brabender, Mackenzie Deathrage, Sylvia Gledhill, Joanne Jarman, Alison Ortega, Savanna Sherwood, Brooklyn Smith and Laurie Smith.
Mother Hubbard's Kids: Benjamin Allen, Dakota Brabender, Christopher Capriotti, Sophie Clegg (understudy), Danielle Cleveland, Madeline Cleveland (understudy), Brianna Jarma, William Jarmin, Nikki Moler, Eddie Sieling, Joey Vella and Brooklyn Yates.
Storybook Preshow and Freak Flag: Abagail Bernard, Katelyn Brabender, Autumn Chamberlin, Karena Hoching, Lynden Jarman, Allison Pivonka, Thatcher Gaines, Sawyer Hauk, Eli Ortega, Thomas Ortega, Tyler Snell, Ashalia Velasco, Jacob Vella, Oliva Vella, Calissa Rasmussen, Lesia Rasmussen, Bo Smith and Katy Smith.


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Georgia's Construction Mechanics & Materialmen's Liens–A Primer
We get telephone calls and emails all the time asking about filing mechanics and materialmen's liens in Georgia. Most people understand that the rules must be followed exactly, but they don't know the rules. In addition, the rules regarding the filing of the liens changed substantially in 2009 thereby forcing everyone to learn new rules.
Read More
Georgia's Notice to Owners–A Primer
Most southeastern states require suppliers and subcontractors to give some sort of Notice of Furnishing or Notice to Owner ("NTO"); however, each state has its own special requirements and relying on one state's requirements to get through another state's requirements will land you in hot water. We get a number a telephone calls each week
Read More


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How To Make a Garden In Flats And Apartments
Flat or apartment gardening is now a days a good option to have some fresh flowers, fruits and vegetables for your home. If you try the method it will be a healthy too. The available place is not a problem if you are ready to spend some for this work. There is no need to waste so much of time for this care because most of them will grow well naturally.
the flowers can use to decorate home or can sell if avialble in large quantity. Instead of having fresh items it will be relaxing work out for your mind and body. Just spend few hours for this and you can be proud to be having some self farmed vegetables and fruits. Just try these simple things and share your experience.
Tips To Grow Vegetables And Plants in Flats and Apartments
- Choose the right plant/seed to grow in your flat or apartment is the first and important thing
- First try with one or two flowering plants or vegetables than starting with a large scale option
- Buy a plastic tray with good width and plant some small type flowering plants in it
- African violet, Norfolk, island pepper, pepperonium, Chinese evergreen are good options for flats
- Ensure that the place is getting adequate sunlight for these plants
- Vegetables like ladies finger, long beans, tomato, brinjal, bitter gourd are easily growing in every where
- You can have pots and flower baskets hang on the suitable place to get more place
- Orchid grape ivy, English ivy, money plant are suitable to grow in this way
- Also try keeping some plants inside the room but just keep these flowers in sunlight once in a week
- For this purpose select snake plant, rubber tree, spider plant etc
- Bonsai are another good options to decorate your flats well
- Many types of attractive and beautiful bonsai are available as flowering plants and vegetables
- Bonsai have the advantage of less fertilizer application and less space
- Any large growing type of tree or flowering plant can be modified to the form of Bonsai
- Choose deep flowering pots for such type of plants is the considerable thing
- All plants as bonsai need to crop well in frequent periods with the help of a pruner
- Aquaskapping is the another good option to make your flat appear attractive
- This is the way in which plants are growing in glass-plastic jars/pots within water instead of soil
- Sea weeds, various aquatic plants can be chosen for this purpose
- Keep such an aquatic plant fitted pot in any corner of your flat or apartment go get a fresh and natural look
- You can choose colorful water plants like lotus, water lilly to make your room appealing
- Keep a fresh and small aquarium in your flat with some golden fish, snails and water capable plants in it
- Empty bins and cans of various items can be well modified to grow vegetables and fruits
- In kitchen also you can keep some green plants in small pots
- While using fertilizers it is better to choose natural fertilizer because it may cause reaction with the plastic pot and create harmful effects
- Vermicompost and liquid organic fertilizers can use for good outcome
- Bad smell producing fertilizers like bone meal is better to avoid


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Company Sponsored Retirement Plans come in a variety of types and have different funding requirements. 401(k) is the most commonly associated term with an employer based retirement plan however there are many others such as 403(b) aka Tax Sheltered Annuity (TSA), 401(a) Money Purchase Pension, 457 Deferred Compensation, Profit Sharing, Defined Benefit Pension, Solo 401(k), DB(k), SEP (Self Employed Pension) IRA, SIMPLE (Savings Incentive Match Plan for Employees) IRA, etc. There are now also the Designated Roth variety of 401(k)'s and 403(b)'s. Choosing between these different plans can affect administrative cost to the employer as well as funding limitations for owners, principals, officers, and employees.
Schedule a complimentary Discovery Consultation to learn more about how Portnoff Financial LLC can help you design the right retirement plan for your business.


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Only certain form data is important to you. That's why Gravity PDF has a number of ways to filter out the unimportant fields in your generated PDF.
It's important to note that only certain PDF templates have these filtering options. All the core PDF templates will support the features discussed below, but premium, custom templates or your own DIY templates may not.
What is Displayed? #what-is-displayed
Gravity PDF will adhere to your form's conditional logic when generating a PDF. That means if the conditional logic determines a field (or entire section) should be hidden it won't be displayed on the PDF. Also, if a user doesn't fill in anything for a particular field it won't be displayed either. Both of these settings can be modified – see Enable Conditional Logic and Show Empty Fields.
HTML and Page fields are also hidden by default, but they can be enabled using the Show Page Names and Show HTML Fields options.
You can also choose to show or hide the form's title using the Show Form Title option.
Hide Specific Field #hide-specific-field
In certain cases you may not want a particular form field from displaying in the PDF. When that's the case you can add the CSS class
exclude to a field in the Gravity Forms editor. You can do this by:
- Navigating to your form's Form Editor
- Select the field you want excluded from the PDF
- Open the
Appearancetab and add
excludeto the
Custom CSS Classfield. If a class is already included ensure you add a space between it and
- Save your form
This technique works for all fields except the Hidden field (which doesn't include the Custom CSS Class field) and Product fields when included in the product table.


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Hey, I just wanted to come up with a short note about the approaching Black Friday / Cyber Monday insanity. Tech companies are running the biggest discounts the entire year. You shouldn't miss out.
Godaddy Black Friday / Cyber Monday Offers is excellent. This is the time to buy web hosting or domain names.


text: Human Rights Observatory International Teams Step Up Search for AirAsia Wreckage Search teams and vessels from Indonesia, Malaysia, Singapore, Japan and the United States are helping intensify the search Friday for the wreckage of AirAsia Flight 8501 that crashed in heavy weather Sunday. Technical teams using metal detectors are scanning the Java Sea as the challenging weather conditions of recent days eases. Search and rescue official Supriadi, who like many Indonesians uses just one name, said it was raining at the suspected crash site on Friday morning, with...Read complete article© Voice of America - Friday, January 2nd 2015


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Some cannabis strains – you know, those strains that are just perfect – are like the BMW of cannabis: wonderfully powerful, long lasting and always reliable, but still a far-too-rare sight. As far as cannabis seeds, our regular seeds catalog blows that problem out of the water, offering a truly stunning pick of name-brand, hard-hitting, history-making marijuana strains, many created specially by our industry breeders and winning Cannabis Cups time and time again, others with a history and name that reach their way back to the roots of cannabis culture. AK-47, Kali Mist, White Russian, and Mango Kush are always top sellers, but there are plenty of different seeds to go around, so take your time deciding.
CBD Crew Sweet and Sour is bred with genes of the notorious White Widow. High CBD levels and a very nice effect.
The Sour Star by HortiLab is out now! 2013 is a great year for new varieties and this sour plant is a power plant! The notorious male East Coast Sour Diesel of the v3 line pollinated the multiple award-winning super Indica StarBud and the outcome is a very good yielder with a unique flavor. Ready for reaping after 9-10 weeks and very potent - great for hash production.
The regular Super Sour Skunk by Hortilab is based on a legendary old school variety - a pre 98 super Skunk clone. Adding East Coast Sour Diesel V3 "Sour Daddy" as a father resulted in a beautiful, sour and skunky strain with a long flowering time of 10-11 weeks. But your eyes will love every day of the wait because the rocket-shape umbels with the long pistils are balm for the retina.
The original Amnesia seeds from Super Strains (formerly known as Hy-Pro Seeds). One of the best and strongest (Haze) sativa's on the market. Winner of many Cannabis Cups. Extremely strong effect and an incredible high. A must have for every cannabis connaiseur. The original Amnesia is available only as feminized seeds.
Afghan Haze by Mr. Nice is an old school strain that took the world by storm and still remains a solid favorite today. She is a hard hitter that is at the pinnacle of heavy medical strains. Afghan Haze has potent mixed highs, offers great yields and has a reasonable flowering time. This is one of the all time classics that can be enjoyed by everyone.
The regular Afghan Skunk by Mr. Nice is also known as "Nordle", a code Mr. Nice used to refer to on the phone when he was smuggling Afghan hashish back in the early 1970s. It was the best hashish in the world and Nordle has been bred to bring back the days of sticky resin, tangy flavor and a high that takes the user to paradise. Particularly suited for short outdoor seasons.
Most infamous strain that has won a numerous amount of awards since 1994.
Great and robust cross between an ancient Afghani and the notorious Skunk #1.
The regular Critical Skunk by Mr. Nice is a very aromatic and high yielding niece of the Critical Mass, a variety that took the European stoner community by storm. It is the perfect choice for novice growers who want a heavy plant within a relatively short period of time. In an indoor plantation one can expect 650-800g/m² after only 6-8 weeks of flowering, depending on the phenotype.
The regular Dreamtime by Mr. Nice is a mixture of old school genetics; Shantibaba selected a range of beginner friendly strains and his pick contains Haze, Northern Light, Skunk and Afghan genetics. You'll achieve the best results in bio and hydro set-ups. Indoors you can expect anything from 400 to 550g/m² after 60+ days of flowering, depending on the phenotype.
Legendary crossing of an Early Pearl, Early Girl and a top quality Super Skunk.
Early Queen x Afghan Haze is a limited edition deviation from the way Mr. Nice tends to operate. It is a fast growing and high yielding hybrid that has multiple old school genetics, bringing them all together in one powerhouse classic. Early Queen x Afghan Haze is fairly easy to grow and will suit all levels of cultivator. It won't be around for long – so get it whilst it is hot.
Early Skunk is a great example of pimped old-skool genetics. Cross between a Early Pearl and a Skunk.
The regular G13 x Skunk by Mr. Nice is an easy to grow plant that thrives well in indoor set-ups, outdoor plantations and greenhouses; suited for the novice and commercial grower alike. Due to the Indica dominance it does not stretch much but achieves very good yield for a small plant. An average indoor harvest after flowering for 7-10 weeks amounts to 500-650g/m².
The regular G13 x Widow by Mr. Nice is the outcome of mating two legendary varieties and combines genetic influences from Afghanistan, South India and Brazil in a single plant. This blend brings forth different phenotypes, from tightly packed and compact Indica to a Sativa with the flowering pattern of an Indica and the nose and palate will be pleased by the varying impressions.
Famous and very effective crossing between the great Haze and the notorious White Widow.
A smart crossing of 3 award-winning monster-strains! A Northern Lights #5, a Skunk and a true Haze.
Mango Haze x Afghan Haze alias "Angel's Breathe" by Mr. Nice is a true connoisseurs choice and is only available for a limited time. It requires some patience as it takes her up to 12 weeks to reach full maturity. Indoors the vegetative period should be limited to less than a week because 50% of the genetic cocktail consists of Haze. Expect 400-550g/m² of very tasty weed.
Mango Haze x Afghan Skunk by Mr. Nice has been nicknamed "Angel Heart" and is another limited time offer. The heavenly flavor makes the palate party and the heart skip a beat from pure joy. Flowering may require up to 10 weeks, but 400-600g/m² of highly potent weed compensate for the wait. Each phenotype will have its own charm and potential to become the angel of your heart.
Luscious crossing between 2 great hybrids! A real treat for mind and tongue.
The regular Master Kush x Skunk by Mr. Nice is based on two living legends of the cannabis culture. Both Master Kush and Skunk have won multiple awards over the past few decades and crossing those varieties resulted in a plant with a special aroma and flavor. Outdoors it can develop such heavy buds that unsupported plants might actually break! Indoors you can expect 500-600g/m².
Very popular old-school medical strain with a very pleasant and calming overall effect on both body and mind.
Legendary combination of the NL #5 Haze and an original Haze. Incredibly pleasant and long-lasting high.
Neville's Skunk by Mr. Nice is a new blend of old school genetics and a limited time offer. Neville Haze and Afghan Skunk have been crossed and the result is a plant with yields of 450-650g/m² and a flavor and aroma that will carry your nose and palate away. The flowering time can vary greatly, with the first finishing after 9 weeks, but most will need up to 12 weeks.


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Brand: Verso Skincare
Verso is Latin for reverse, as in the backside of a painting or the back view of a dress. It is what is normally hidden underneath, the mirrored view. In a metaphorical sense, you could say it means going your own way, being different. And Verso is a very different kind of skincare.
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text: Was thinking of heading way up past the NF of the snoqualmie to do some alpine lake hiking and stuff :WINK . Gonna follow the warehouser roads and was wondering how far up past gate SR 10 i will be able to get? Do i need a permit? Any special hours that the gates are open or closed? Any information would be greatly appreciated. Thanks Scott


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Home > About the Fed > Board of Directors & Councils > Board of Directors > David R. Hunsicker
David R. Hunsicker, who has more than 43 years of banking experience, is chairman, president, and CEO of New Tripoli Bank. Hunsicker became a member of the Federal Reserve Bank of Philadelphia's board of directors in 2013 and is audit chairman for the board. He is the Pennsylvania State representative to the Independent Community Bankers of America, a group representing more than 5,000 community banks nationwide. He is also active with the Pennsylvania Association of Community Bankers and the Pennsylvania Bankers Association. Previously, he served as finance chair and chairman of the board of directors at Lehigh Carbon Community College.
Hunsicker has an associate's degree in business management from Lehigh Carbon Community College and a certificate from the American Institute of Banking.


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Connecting People To Nature
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Mekanagadde Homestay is certified* from Karnataka Tourism Department.
Bookings can be done through direct banking or net-banking. Ask for bank account number and details. Remaining to be paid through only cash at homestay. Mekanagadde Homestay is also near to sakleshpur hence we concentrate both Chikmagalur and Sakleshpur.
Address: Mekanagadde, Mudigere, Chikmagalur, Karnataka – 577132
Phone numbers: (+91) 9945104606, (+91) 9481009907, (+91) 9241222504, (08263) 239151
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Severe weather in the first quarter put a chill on U.S. restaurant visits, but delivery orders and beverage-focused brands saw traffic increase, according to research released by The NPD Group Inc. on Wednesday.
While traffic at all U.S. restaurants declined 1 percent in the quarter, spanning January through March, the Port Washington, N.Y.-based market research firm found that delivery orders increased 4 percent.
"Extreme weather conditions affect consumer behav
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Apple is on a release rampage. After releasing the iOS 10.3 Beta and macOS 10.12.4, the Cupertino giant is now rolling out an update for Apple Watch users in the form of watchOS 3.2 Beta 1, where the company is adding two new features: Theater Mode and SiriKit.
While SiriKit gives the permission to developers for accessing the Siri within their application, the new Theater Mode switches off the Apple Watch when you enter a theater not to annoy others. However, you receive all the notifications and other stuff even on Theater Mode.
Also Read: Night Shift Mode finally makes its way to macOS with the Sierra 10.12.4 beta update
The Theater Mode was previously introduced with the watchOS 3.1.3, but it never went live for public users. Also, the Theater Mode will be added to iPhones as well with the iOS 10.3 update and can be accessible via the control center toggle.
Sadly, this new watchOS 3.2 Beta 1 update is only for the registered developers, but Apple will soon roll out the public beta for this version as well. If you're an Apple beta registered user, then you will receive a notification on your Apple Watch regarding the latest beta update, and the update weighs 242MB, and you need to be connected to the internet to update the Apple Watch.


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Operations Center
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Eccles Broadcast Center
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Salt Lake City, UT 84112
(800) 866-5852
(801) 585-6105 (fax)
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Read selections from pioneer journals. Discuss the thoughts and feelings read in the journals.
Discuss lifestyles and times of the pioneers. (Refer to the Heritage Gateway Curriculum for a list of essential questions/themes that may be related.)
Provide a model as an example of a short vignette in first person that shows a specific story illustrating a character attribute. You may wish to use an excerpt from Edgar Lee Master's Spoon River Anthology, a short poem from Cynthia Rylant, or a teacher-made character sketch. Discuss the character of the pioneers. (OPTIONAL: Give plenty of drama to the presentation: costume, lighting, effective oral interpretation.)
Give background about the pioneers: statistics and causes of death, motivations and hardships of the trek, examples of burial and pioneer cemeteries, specific stories about many of these pioneers who died along the way. Use visuals, multi-media presentations, the Internet to supply information. Show how students can research on their own to find out information about a specific pioneer. Discuss the possible causes of death, hardships, and problems of the pioneers.
Give the writing assignment: Students find at least two stories that illustrate a specific character attribute (possibly from a list of attributes), then write about it in first-person narration. The story must be historically accurate, detailed, and directly support the character attribute.
Have students use the writing process to revise and edit their drafts, using peer response groups, teacher conferencing, mini-lessons about character sketches or poem form, etc. Making a class anthology of final draft character sketches may motivate good writing as they work towards class publication.
Illustrate the oral interpretation expectation of these character sketches by explaining a product guide and/or modeling how their character sketches may be performed. Schedule the order of performances and encourage costuming.
On the day of performance, set the students up in rows imitating tombstones
in a cemetery. Students sit with their backs to the audience (another class
or part of the class at a time), then stand up and turn around to recite their
vignette. Memorized lines are most effective, although students can read their
part if they have practiced with good oral interpretation. Have low lighting
or spot-lighting for each presentation, if possible. Background music and/or
sound effects may also be effective.
Assessment Plan:
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PAULESI gets set to receive new intake of ninety five new students.
The Pan African University Institute of Life and Earth Sciences (including Health and Agriculture), University of Ibadan, Ibadan, Nigeria recently concluded its highly competitive selection process for the 2016/2017 session and offered admission to 107 students.. Ninety five of the students representing 25 nationals from different countries in Africa offered admission have finally indicated their willingness to take up the offer. The students will be arriving at the campus by 21st November, 2016Read more


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50s Karaoke Classics
Release Date: 13 June 2005 | Certificate: Exempt
£5.19 includes FREE UK Postage (other delivery options available)
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Sing along to your favourite songs of the 1950s. Tracklist includes: Rock Around The Clock, Hound Dog, Thatll Be The Day, Whatever Will Be Will Be, Be Bop A Lula, Fever, Great Balls Of Fire, Blueberry Hill, When I Fall In Love and Chantilly Lace. Features ten tracks in total.
Blue Screen Option, Vocal Version, Karaoke Version, Backing Version
Release Date: 13 June 2005
Certificate: E - Exempt from Certification
Region 0
Running Time: 45 minutes
Main Language: English
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Esther Rantzen, the television presenter, has claimed she was the victim of police dishonesty like that encountered by Andrew Mitchell.
Officers falsified a record of her husband's conversation with traffic police after being pulled over, Miss Rantzen claimed, in an echo of the 'Plebgate' scandal.
The claim came as MPs launched a blistering attack into senior police officers' handling of the affair, in which officers were accused of plotting to bring down Andrew Mitchell, the former chief whip.
Miss Rantzen said: "I was with my family, driving down the motorway, and I was stopped by traffic police. They asked my husband, who was driving, for his driving licence.
"He said: 'I'm actually going to need it because we are going on holiday. Can we do it another way?'"
"When we saw the police record of the conversation, the policeman said my husband had said: 'I am Desmond Wilcox. I am a television personality. This is my wife Esther Rantzen. Don't you know who we are?'"
"For a generation of police people, they had absolute power. They had been able to write up their own records and had been unassailable in court. Plebgate has said, 'Wait a minute, guys'."
Mobile phone recordings and CCTV means police can no longer create "fictional records" of their encounters with the public, Miss Rantzen told Murnaghan on Sky News
Andrew Mitchell, the former chief whip, resigned from government last October after he swore while talking to police on duty in Downing Street and allegedly called them "----ing plebs" - an incendiary term he denies having used.
Mr Mitchell was also initially claimed to have said: "I'm telling you – I'm the chief whip and I'm coming through these gates."
That version of events was undermined after one of the alleged witnesses admitted not being there.
David Davis, the former shadow home secretary, said Mr Mitchell should be immediately reinstated and suggested Mr Cameron had been slow to act.
"Government does move ponderously on these things, and there will be a major reshuffle, I'm sure, in the next six months or so at Cabinet level and at that point he should be returned," he said. "That's plainly my view, but it's also plainly the view of the vast majority of the parliamentary party."
Mr Davis said the "whole of the British public" had believed the police officers' account, leading to the "widespread vilification" of him and his family.
MP have now concluded there were "gross procedural irregularities" in the way three police forces investigated Police Federation representatives who helped bring Mr Mitchell down during an anti-cuts campaign.
Three officers are accused of misrepresenting Mr Mitchell after meeting with him, falsely claiming that he failed to explain what he really said to police at the Downing Street gates. That claim was contradicted by Mr Mitchell's private recording of the encounter, but the three were cleared of gross misconduct by their chief constables.
The Home Affairs Select Committee said those chief constables showed an "absence of leadership at a critical time" and questions being raised about potentially "unlawful" actions by an assistant chief constable of West Midlands Police, one of the country's largest forces.
Mr Davis said it was "extraordinary" the three Police Federation representatives, had not faced misconduct charges given the evidence against them.
"It's extraordinarily serious for the police. We expect the truth, the whole truth, nothing but the truth to be the absolute iron-clad core of policing," he said. "It's not just about the issue of three policemen. It's about whether or not this sort of behaviour is seen as acceptable by the entire system."
Alex Marshall, the chief executive of the College of Policing, said the IPCC should have been placed in full control of the investigation from the beginning. The reputation of the police has been damaged by the affair, he added.


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"GT Resource Teachers: Guides on the Path"
answers compiled by Kathee Jones
JAGC wanted to know what a GT resource teacher does, so we asked them. Many thanks to the Jeffco GT Resource teachers for answering JAGC's questions and sharing about the expertise, challenges and joys that are part of their important role in supporting gifted education.
What is a GT Resource Teacher? ("RTs")
A GT Resource Teacher is a link between the schools and the GT Department, providing the following:
guidance with setting Advanced Learning Plans (ALP) goals
progress monitoring
answering questions
professional development
meeting with parents
meeting with teachers (group and one-on-one)
researching best practices
collaboration with Instructional Coaches
collaboration with other Departments
educating teachers/parents/administration, etc. about gifted
create and maintain a body of evidence for identification
data collection
data analysis
ALP reviews
assistance in programming options
online parent and teacher course facilitation
implement district initiatives
implement department initiatives
work with students
present monthly parent seminars
present at state, national, and international conferences
serve on various district committees
How do GT Resource Teachers benefit classroom teachers?
GT Resource Teachers benefit classroom teachers in many ways and respond to teacher needs as they arise. They help teachers nurture and program for their gifted students. For example, an RT shares that "we often meet with individual teachers or groups to discuss their gifted students, problem solve, help develop enrichment and extension opportunities, explore programming options, and support student social emotional development." RTs also conduct staff training at schools or other district venues on a variety of topics. Another avenue of professional development that RTs offer is the option for teachers to take online courses or inservice or graduate credit, focusing on different areas of giftedness.
The GT department facilitates a yearly screening for gifted students using the CogAT assessment which occurs district-wide in second grade. Once the results are available, the RTs benefit classroom teachers by discussing assessment results and assisting in next steps. They meet with teachers to review the results and build a body of evidence to support the creation of Advanced Learning Plans (ALPs) for gifted students. RTs also meet regularly with teachers to set goals for students' ALPs and monitor progress of those goals. Teacher support is a main component of Jeffco GT Resource Teachers' work.
Who else do GT Resource Teachers collaborate with?
Jeffco GT Resource Teachers also collaborate with :
Classroom Teachers (General Education and GT Center)
Instructional Coaches
DLEA (Department for Learning & Educational Achievement)
SPED (Special Education)
Ed Tech (Educational Technology)
ESL (ESL/Dual Language Programs)
What might a Resource Teacher's day look like?
Jeffco GT Resource Teachers must be flexible. One RT thinks of it as working in "chunks", depending on the task.
For example, RTs spend the first two weeks of the school year visiting the 20+ schools they each serve, meeting and building relationships with each schools' BLs (Building Liaisons), principals, and Instructional Coaches. If the RTs have new schools that they are serving, this takes additional time. Then RTs make sure lists of all students with ALPs are available and check in with Center program teachers.
CogAT season can take 6-8 weeks to get materials to some sites, collect materials, analyze data, and meet with Second Grade teachers to discuss results.They also begin the ALP creation for those who newly qualify. During this time RTs also gather CSAP data and identify 5th & 6th grade students and begin writing those ALPs. RTs work with classroom teachers to set appropriate ALP goals with students alongside the goal-setting process. With secondary schools the Resource Teachers address ALPs through the NAVIANCE system.
Other responsibilities include: trying to visit each school once a month, providing staff development, providing and attending professional development for Center teachers and Building Liaisons, and presenting at state and national conferences. RTs also attending GT staff meetings, Division of Instruction meetings, instructional coaches meetings, and various committee meetings. They attend several RtI (Response to Intervention) meetings and sometimes IEP/ALP meetings with teachers, students and parents to help support schools in problem solving appropriate interventions and strategies that support individual GT learners.
One RT also notes that "a large role of being a GT resource teacher is supporting parents, educating and answering questions of our students' parents."
What kind of background do Jeffco's GT Resource Teachers have?
Jeffco's GT Resource Teachers have a varied background in education, from elementary through secondary. All of the Resource Teachers have multiple degrees. All have a masters degree in gifted education or are endorsed in gifted education. and some of our Resources Teachers have doctorates in a variety of areas. There are also Resource Teachers with their administrative and Principal's licenses.
Each RT has a passion in specific gifted topics, have become experts in the most updates research, and have a strong technology background. They've published in state and national journals and periodicals. Our Jeffco Reasource Teachers have also provided professional development at local, state, national, and/or international conferences. They have have developed and presented Parent Seminars on a variety of GT topics, as well as developing and teaching numerous GT on-line courses for teachers and parents.
What is the best thing about being a GT Resource Teacher?
Our Jeffco GT Resource Teachers value the relationships and enjoy working with a variety of teachers, principals, parents and students. There is the satisfaction of supporting GT learners with resources, strategies, and problem solving as a team to meet the students needs; JAGC was told "I believe that our expertise allows us to help view the child with a different lens on best practices for supporting gifted learners characteristics, learning profiles, and their social/emotional needs." Another nice thing about being a RT is the variety and flexibility of the day. It was noted that "the role requires keeping a number of spinning plates in the air at all times. For the most part we try (and are very good at) being proactive, but often must be reactive as things come up."
What is the most difficult challenge in being a GT Resource Teacher?
The challenges noted stemmed from the GT Resource Teachers desire to meet the varied needs of all of Jeffco's individual gifted students in their different school environments. RTs support approximately 20 schools each and it is difficult to provide for all the needs in a timely manner. Further, "some schools welcome the support of the RT, while other schools would prefer not to be involved with us". The RT's role is complex as they consider what is best for the student while at the same time support the needs of the school, teacher, parent and make sure that best practice for gifted learners is in place. The GT Resource teachers find they must spend a great deal of time overcoming misperceptions about the characteristics of a gifted learner and educating staff and parents about the application of best practices to ascynchronous students. It was noted that "acceptance of the body of evidence is sometimes difficult to explain, and we are often asked 'how can this child be gifted--they don't do their work' when in fact the work might not be appropriate for the student". Another difficulty is being pulled in may directions and managing the multitude of their work. In addition to supporting schools Jeffco GT Resource Teachers serve on many committees and work groups.
How do I contact the right person if I have questions about my GT student?
Our GT Resource Teachers in Jeffco support approximately 20 schools each and often cover a large geographic area. Parents should always begin by contacting their student's teacher first to discuss any questions/concerns. If it is a GT specific question, the teacher will direct parents to the GT Resource Teacher who will contact the parent either by voice or email, or the parent can view the list of RTs on Jeffco's GT School Contact web page. If a parent has discussed the issue with the teacher and has not come to a resolution, parents should contact the principal and/or instructional coach. If parents want additional input, they should contact the GT Resource Teacher assigned to their school. Teachers and principals also contact the GT Resource Teacher regarding questions/concerns.
Is there anything else about GT Resource Teachers that it would be helpful to know?
GT Resource Teachers are passionate about instruction. They are housed at schools to offer support. The RTs facilitate on-line classes with teachers regarding best practices in GT for content and social/emotional support. They also provide information for teachers to obtain their GT Endorsement. They have have monthly meetings with Jeffco GT Center teachers and support them as a school to develop consistent practices within their Center. GT Resource Teachers not only work with classroom teachers but often collaborate other departments, as well as with parents and students and within the community, to support gifted learners.
For more information about Gifted and Talented Education in Jeffco, see the district's site.


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Thread: database restore to other LPAR
06-23-11, 00:44 #1Registered User
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- Oct 2010
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Unanswered: database restore to other LPAR
we have installed a new DB2 V10.1 in a new LPAR(Z/OS). we have planned to migrate all the DB2 8.1 database ,tablespace to the new LPAR. Just wanted to know if the Dump and restore will be a good option to achieve this migration since we dont have tools to perorm this action. Could you please enlighten me.


text: Filter + FILTER CONTENTS × Topics arts business current affairs education policy Topics arts business current affairs education policy Video Gallery Your browser does not support HTML5 video. Arts Artist Lee Ming Wei Video Excerpt: Artist Lee Ming Wei describes his installation Bodhi Tree Project, during a discussion at the Asia Society during Asian Contemporary Art Week, May 11, 2009. (3 min., 41 sec.) Pagination First page « First Previous page ‹ Previous Page 1 Page 2 Page 3 Page 4 Current page 5 Page 6 Page 7 Page 8 Page 9 Next page Next › Last page Last » Current Affairs / New York Feminism and the Indian National Movement: Kamaladevi Chattopadhyay (Complete) Feminist activists, historians, and writers Gloria Steinem, Ellen Dubois, and Ruchira Gupta discuss the legacy of Indian freedom fighter Kamaladevi Chattopadhyay. Watch Now Policy / Hong Kong Survival Kit for Media Companies: Transformation and Culture (Complete) South China Morning Post CEO Gary Liu talks about the digital transformation and innovative culture that shapes the future of media companies. Watch Now Arts / New York Burmese Artist Htein Lin Uses Art To Heal Former Political Prisoners in Myanmar Burmese artist Htein Lin helps former political prisoners heal from their experience through an art project called 'A Show of Hands.' Watch Now Current Affairs / New York Mohammad Javad Zarif: Nuclear Weapons 'Not Part of Our National Interests' The Iranian foreign minister described his country's plan in regard to the nuclear deal. Watch Now Current Affairs / New York Iranian Foreign Minister: 'We Derive Our Legitimacy From the Public,' Not U.S.-Provided Weapons Mohammad Javad Zarif contrasts the Iranian style of government with those of its adversaries in the region. Watch Now Policy / New York Islamic Republic of Afghanistan: President Ashraf Ghani (Complete) Ashraf Ghani and Fareed Zakaria discuss the prospects for peace and security in Afghanistan. Watch Now Current Affairs / New York Ken Burns and Lynn Novick Describe Vietnamese Reaction to 'The Vietnam War' The filmmakers discuss how their new documentary is opening up debate among Vietnamese audiences. Watch Now Current Affairs / New York Pakistan FM Says Country Not Responsible for Afghanistan's Problems Khawaja Muhammad Asif responds to criticism from President Trump and others that Pakistan is complicit in its neighbor's troubles. Watch Now Policy / New York Islamic Republic of Pakistan: Foreign Minister Khawaja Muhammad Asif (Complete) The Pakistani foreign minister discusses a range of subjects with Steve Coll at Asia Society. Watch Now Current Affairs / New York The Legacy of Vietnam (Complete) Ken Burns and Lynn Novick give an inside look at their new series on PBS 'The Vietnam War.' Watch Now Policy / New York Indonesian Foreign Minister Recounts Meeting With Aung San Suu Kyi Retno Marsudi describes her discussions with Myanmar's de facto head of state regarding the Rohingya refugee crisis. Watch Now Policy / New York Republic of Indonesia: Minister for Foreign Affairs Retno Marsudi (Complete) The first female minister for foreign affairs of Indonesia gives insight into the country's vision of peace and stability. Watch Now Pagination First page « First Previous page ‹ Previous Page 1 Page 2 Page 3 Page 4 Current page 5 Page 6 Page 7 Page 8 Page 9 Next page Next › Last page Last »


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Chet and Lori Esther spent 30 years building a 4,700-acre grain operation, construction company and semi truck and trailer dealership. Now they are in the process of transitioning the multiple-entity business to their sons Ryan and Chad. The Esther's farming operation consists of:
EFFCO (Esther Family Farming Company)
Chester Enterprises
CE Construction
Esther Management Company
July 1, 2010
A wise parent does not prepare the path for the child, but instead prepares the child for the path. That's the learned perspective of Chet and Lori Esther.
July 1, 2010
Lori Esther shakes her head in disbelief at the thought of her sons farming together.
July 5, 2011
With only a few years until retirement, Beardstown, Ill., farm owners Chet and Lori Esther are working hard on their succession plan and financial security.
July 5, 2011
How to regroup when life gets in the way of succession planning. Life happens. It especially happens on a farm where three busy families live, work and play.
July 5, 2011
Chet Esther can rest easier now that he has inked a buy-sell agreement between himself and his sons, Ryan and Chad.
July 5, 2011
An assessment tool helped brothers Chet and Ryan Esther better understand each other.


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1 in stock!Place order by 17:15 (+2 GMT) for same business day shipment!
The UDG SlingBag Trolley DeLuxe specially designed to protect your LP's or DJ equipment during travelling. With a capacity up to 60 records, this Bag is perfect for mobile DJ's use or as an optimal complement to the UDG Sling Bag.
Constructed from high-quality fabrics, foam padded walls, electroplated zipper, comfort top-carry handle, detachable shoulder strap, and in-line wheels will provide secure and dynamic travel experience.
Water Resistant Nylon 420D
Retractable handle
Large front pocket
2 side pocket for accessories and smaller gears
Comes with 2 CD Wallet 24
Integrated combination lock
|Outer Dimensions (cm)
|40 x 45.5 x 31
|Inner Dimensions
|31.5 x 32 x 20
|Vinyl Capacity
|Weight (kg)
About Brand
Authorized dealer
UDG rules the market of DJ bags and cases. Once they noticed old vinyl bags are too heavy and uncomfortable, so decided to create something light, transportable but durable too. If Carl Cox, Fatboy Slim and Tiesto all found something, we believe you also would. UDG works for the safety of your DJ equipment.More UDG products


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ww2 womens u.s army officers garrison cap wac/nurse
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superb original ww2 u.s army officers womens garrison/overseas cap.o/d green colour sz 22 differs to mens cap with its distinctive banana shape . please on this very hard to find original garrison cap in near mint condition with absolutely no moth damage, repairs rips tears. no sweat marks tobacco or pet odours.inside or out correct gold bullion and black silk officers trim also with gold lt bars. purchased around 5 years ago with a one piece u.s army nurses uniform ,please check out my other listing. this is a no reserve, no buy it now auction so item will sell starting at just 99p please watch this item, you may get a bargain winning bidder will definately not be dissapointed with the quality item ,if you have been looking for this rare cap type please look no further. overseas shipping costs will differ please contact for details.


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Baby Time
Nov 29, 2017— 10:30 am
Other upcoming dates: Dec 06, 2017, Dec 13, 2017, Dec 20, 2017, Dec 27, 2017, Jan 03, 2018, Jan 10, 2018, Jan 17, 2018, Jan 24, 2018, Jan 31, 2018
Don't wait to start reading to your baby!
Babies and their caregivers are invited to join us for a half hour of books, movement, songs and play! Baby Time is specially designed for infants and toddlers (up to 3 years) and their caregivers and encourages language development and learning through stories, rhymes, and music.
Baby Time is every Wednesday morning from 10:30 – 11:30 am. Be sure to check our program calendar to see any changes due to our holiday schedules. For more information about Babytime, please call us at 513-3133, or send an email to us!.


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The Tennis Coalition has funded several court renovation projects over the years and is currently spearheading its biggest project to date: the renovation of the Golden Gate Park Tennis Center into a city-wide treasure that will be home to all tennis enthusiasts.
Our hope is to raise the necessary funds to update and upgrade the legacy courts and clubhouse in Golden Gate Park which were constructed between 1894 and 1954. The project is a collaborative partnership with San Francisco Recreation and Parks Department and the San Francisco Parks Alliance which serves as our fiduciary sponsor.
Since 1894 players of every age and ability have learned, played, and competed in an iconic location in Golden Gate Park. Billie Jean King and Rosie Casals played here. Peanut Louie Harper played here. And today, players from tots to seniors come to work on what matters — a love of tennis, perseverance, friendships and sportsmanship. That's the vision fueling a re-designed, re-imagined Golden Gate Park Tennis Center (GGPTC).
GGPTC will bring together tennis enthusiasts of all ages, abilities, and backgrounds and draw our community together for year-round healthy recreation ranging from instruction and casual play to leagues and tournaments. It will be a place to develop skills and habits that can enrich and improve lives and to connect and have fun around a shared interest. The Center will encourage excellence. It will be well-designed, in harmony with its Golden Gate Park setting, safe and accessible, and once again be the hub of San Francisco tennis, strengthening the SF tennis community. With shared tennis interests in common, the new Tennis Center will create formal and informal places to learn and gather, where a broad variety of users of all ages and skill levels can observe and learn by watching good players. Most of all, the Center will be deeply San Franciscan in spirit — vibrant, accessible, beautifully designed, — and open to all.
The Golden Gate Park Tennis Center has a remarkable history. Now it's time to think about the future.
- Cracked court surfaces, eroding base
- Poor drainage
- Inadequate lighting
- Outdated, undersized clubhouse
- Non ADA-compliant
- Absence of a tournament-level competition court
- Replace all courts from their foundation to improve drainage and resulting court conditions.
- Construct a sunken court with bleachers for tournament play.
- The new courts will have proper spacing between them which will improve circulation and allow for efficient programming and simultaneous use of courts for a variety of user groups.
- Construct a new, larger clubhouse to host greatly expanded program offerings (including youth programming) as well as amenities found in other clubhouses (locker rooms, pro shop, reservations desk).
- Add lighting for night-time play.
- New landscaping plan will include patios and gardens which will be perfect for socializing and watching matches.
GGPTC News
- 116th Annual San Francisco City Championships
17 Sep 2017
- Five Questions For… Robert Kaliski
15 Sep 2017
- Five Questions For… Dick Gould
19 Aug 2017
- First Annual TLC Play Day at Golden Gate Park Tennis Center
19 May 2017
- Tennis, Bagels & the GGPTC renovation project
20 Feb 2017
- Tennis and Learning Centers Filling a Need in San Francisco
25 Jan 2017
- Great Turnout for Nov. 16 Community Meeting on GGPTC Renovation
16 Dec 2016
Questions? Please contact:
Julie Exley, Executive Director


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apparently is certain people, I am also using chrome for the moment, and I dont get any warning messages.
hey guys i was in the CA section and i clik on a thread and this pops up
so wot do u think
Oh hai der.
apparently is certain people, I am also using chrome for the moment, and I dont get any warning messages.
Click Here to Become a MPGH Premium Member by Donating $25 or More.
If anyone claims to be me via MSN/Skype/Email or any other source outside of MPGH private or visitor messages, IT'S NOT ME!
They are trying to trick or scam you. Report them immediately and PM me here for verification.
"Dont confuse my personality with my attitude. My personality is who I am. My attitude depends on who you are." Frank OceanModerator: 5/2009-10/2009 | GMod: 10/2009-10/2010 | Staff Administrator: 10/2010-Present
Stupid/Pointless Private messages = SPAM, SPAM = BAN.
Depends what version of chrome you're on.
Happens to me too.
Am usin chrome too, the latest one, maybe its about your AV's web filtering?
I'm using Chrome, happened to me just then. Is this anything to get worried about?
Yeah this has happened to me b4 but not nao :|
I get it now, do you notice there is another bold link? That is causing the problem.
Sorry? I don't quite understand.
I has Chrome, not happened to me yet. :P
In the screenshot, there are two black bold links, one is mpgh, the other one is explosm, a comic sharing website.That website is causing google chrome to react this way, giving you that warning, because there are probably people who posted in a particular thread who have either their signatures or avatars.
If more ppl starting to get this error when you visit some pages of mpgh.
Leave me a vm.
-Rest in peace leechers-
Your PM box is 100% full.


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As surely as we can infer that all progeny have had parents, we can be confident that the diseases at present thought to be "idiopathic" have origins in the differential effects of environment and genetics that await discovery.
Epstein-Barr virus (EBV), or human herpes virus 4 (HHV-4), is an obvious and recurrent suspect for the origin of inflammatory diseases. EBV transforms some infected B cells and has the potential to commandeer the immune system and inflammatory response, as is well known from EBV-induced infectious mononucleosis. Once infected, EBV persists in the host for life as a latent infection with a viral reservoir in resting memory B lymphocytes. Gene products expressed in latency and the low level of lytic virus continuously emerging from latency provoke sustained immune activation of focused anti-EBV immune responses. In the billions of seropositive, chronically EBV infected, healthy mass of humankind, the ~1% of all CD8 T cells specifically directed against EBV antigens belies the astonishing level of immune attention we humans ordinarily dedicate to this single virus (1). Every higher primate studied has its own unique specific EBV-like variant with little to no cross-species adaptation. Also, and unfortunately, there are no close homologues to EBV in the mouse and EBV does not infect the mouse, greatly retarding its experimental study.
The impressive magnitude of the human host immune response to EBV and the many now known pleiotropic interactions that this virus has with host inflammatory responses are clear opportunities to generate the dysregulation of immunologically mediated diseases. EBV has become, for example, a strong candidate etiologic agent for multiple sclerosis (reviewed in (2)). Indeed, for autoimmune diseases, the virus infection by itself is not the apparent culprit. Rather, the prime suspect is the host inflammatory response, as influenced by or in response to EBV gene products.
Interferon-alpha (INFα) induces dendritic cell differentiation with associated antigen presentation. SLE patients with active disease have been shown to have elevated levels of INFα in their serum (3). Multiple groups have found increased expression of interferon inducible or interferon stimulated genes in lupus patient peripheral blood mononuclear cells. Also, interferon activity, as measured by a gene expression reporter assay, correlates with disease activity, select autoantibody subsets, and genetic polymorphisms in some lupus-associated genes (reviewed in 4). How and when in the course of SLE pathogenesis these dysregulated interferon responses begin; and specifically, whether they precede the specific abnormalities of lupus autoimmunity or are a consequence of the particular immune responses characteristic of lupus, is not now known. Curious differences in the IFNα production of peripheral blood mononuclear cells of SLE patients compared to healthy seropositive controls in response to TLR9 ligands have already been described (5). Endogenous TLR and non-TLR pathways stimulate interferon production through various immune complexes and autoangenic nucleic acid/protein complexes and are reviewed in (6).
In this issue of the Journal Quan et al show that plasmacytoid dendritic cells (pDC) from healthy individuals produce high levels of IFNα in response to EBV (7). Induction of IFNα by pDC is stimulated by EBV binding, not necessarily requiring viral replication, and requires endosomal acidification and TLR9 engagement. Small RNAs, or EBERs, which are found in latent and lytic EBV infection also induce IFNα production through TLR7 engagement in pDCs. In latently infected B cells EBERs induce type I interferons via RIG-I, a pathway that is independent of toll-like receptors (TLRs) (8,9). These findings set the stage to merge two now extensive and previously largely independent literatures, one focused on the role of IFNα in SLE and the other on EBV in SLE, to develop a more complete conceptual construct of lupus pathogenesis.
The possibility that SLE is associated with EBV infection has been building sporadically since the first association was first accidentally found in 1969 (10). Since then the hypothesis that EBV somehow causes lupus has been entertained, discarded, and finally convincingly resuscitated (11, 12). The association of EBV infection with SLE is most convincing in children where the lower background level of infection in the controls provides much improved statistical power (12) relative to adults. At this point, not only has the serologic association has been replicated multiple times, even in adults (13), but the association has also been found by recovering viral DNA sequence (12,14).
EBV has many properties that make it an ideal etiologic agent for SLE. EBV is ubiquitous in the human population which is required based upon the wide-spread occurrence of lupus. EBV makes its own version of IL-10, which would be expected to encourage TH2 responses, perhaps influencing the course of humoral autoimmunity in SLE. EBV produces BHRF1 (which has a protein structure similar to Bcl2) and inhibits apoptosis which could allow continued life of cells that should die in order to avoid autoimmunity (6). Clearly, the presence of increased levels of IFNα in sera from SLE patients and the induction of SLE by interferon treatment leads to the expectation that a virus causing lupus would be expected to induce interferon. (To complicate these issues CD21 the major receptor for EBV has been also shown to be a receptor binding IFNα (15).) EBV induces lupus-oriented humoral autoimmunity as part of its natural history of disease of infection, making the idea that it might be involved in generating the autoimmunity of lupus seem less far-fetched.
Although early control of EBV infection is determined at least in part by the innate immune system, adaptive T cell responses are primarily involved in long-term suppression of EBV in latency and in episodes of reactivation. Regulatory T cell numbers and activity is decreased in blood from infectious mononucleosis (IM) patients compared to EBV seropositive controls (16). Expansion of T cell responses after EBV infection leads to inflammatory cytokine production and B cell help, thereby inducing non-specific autoimmunity in infectious mononucleosis. Indeed, the autoimmunity has both specific and precursor characteristics of lupus autoimmunity (17, 18). How these various interactions between EBV and the immune system may, or may not, be specifically dysregulated in SLE remain to be explored.
The host immune response to EBV is complex and complicated by the many strategies that the virus has to persist in the host and avoid immune recognition; latency is only one of these. The major viral surface glycoprotein binds CD21 (complement receptor 2) and with the help of HLA class II molecules gains entry in to the B cell (19). Antibody responses against the surface protein are virtually universal among those infected, while antibodies binding other proteins, Epstein-Barr Nuclear Antigen 1 (EBNA1), EBNA2, Early Antigen, EBNA3A, EBNA3B, and latent membrane protein-2 (LMP-2) are progressively less frequent. The cellular response of CD8 T cells are most consistently directed against EBNA3 with other antigens, including EBNA1 being more of the focus of CD4 T cells. Class I HLA antigen presentation of EBNA1 is partially inhibited by a glycine-alanine rich central region of the protein (20).
Other autoimmune irregularities accompany EBNA1 immunity. The initiating events for autoimmunity of anti-60kd Ro and anti-Sm B appear to be consequent to the formation of separate cross-reactive antibodies. These are antibodies that bind EBNA1 structures and also bind structures in 60kD Ro or Sm B, respectively (Figure 1). Relative to healthy controls, lupus patients have not only a higher frequency of anti-EBNA1 antibody responses, thereby making this particular adaptive immune response a risk factor for disease beyond the association with EBV infection, but lupus patients also a tendency to produce anti-EBNA1 heteroimmune responses that predispose to forming cross-reactive self antibodies (21). Further, EBNA1 expression in mice induces anti-double stranded DNA and anti-Sm antibodies (22), showing that EBNA1 can generate autoimmunity in a naïve mammalian immune system. These and other data are consistent with the host response to EBNA1 being of critical importance in the pathogenesis of SLE. A hypothetical model for this process is presented in Figure 1.
SLE patients have a 10 to 100 fold more active EBV infection, as measured by viral load in peripheral blood, by the frequency of infected B cells, or by the amount of virus free in serum, seemingly independent of concurrent immunosuppressive SLE therapy (23–25). Extending the observations of Quan et al (7) by predicting that greater IFNα production by pDCs in those carrying a larger EBV viral load should increase the risk of developing or maintaining the pathologic changes of SLE. (The demonstration is so far lacking that an increased EBV viral load with greater IFNα production precedes the onset of SLE or that the increased load exacerbates the pathology accompanying lupus autoimmunity, once established.) The increased viral load is also consistent with the EBV specific T cell defect long appreciated in SLE (26) with higher CD4+ and lower CD8+ EBV-specific T cells (24).
Quan et al, unify two previously independently developed concepts of SLE pathogenesis: the role of type I interferon and dendritic cells (5) and the many lines of evidence now known to implicate EBV in SLE. The data from Quan et al show that EBV induces IFNα from plasmacytoid dendritic cells, consistent with both of these hypotheses, and thereby adding another finding consistent with SLE being caused in part by EBV (or, more specifically, by the host response to EBV) (11). In addition, the rapidly expanding list of DNA variants associated with SLE, now >30, includes a few genes that specifically relate the host response to EBV infection and interferon (e.g., IRF5, TYK2, & STAT4) and a larger sub-set of putative lupus disease risk genes that influence EBV infection in the host.
As the action of viral gene products on the immune system are explained, the progressively more detailed knowledge of the host immune response has identified potentially important relationships. Small EBV RNAs (especially EBER1) form complexes with the La antigen and bind to TLR3, inducing type I interferon and other inflammatory cytokines (27). EBV infection also induces an expansion of activated T cells with associated expression of cell surface markers and inflammatory cytokines (1), many of which contribute toward the symptoms found in primary EBV infection, some of which are also found in lupus (e.g., fever, myalgia, arthralgia, fatigue, malaise, and lymphadenopathy).
Although Quan et al. focus on generation of interferons by pDCs through EBV, other work has shown that EBV interacts with TLRs and upregulates type I interferon and interferon inducible genes (Figure 2). UV-inactivated and untreated EBV increases TLR7 expression in naïve B cells. EBV binding also increases interferon stimulated gene expression and EBV/TLR interactions enhance B cell proliferation (28). Work from the Zhang laboratory (29) demonstrates that the major latent protein of EBV, latent membrane protein-1 (LMP-1), is able to induce expression of several interferon stimulated genes in transfection experiments, surprisingly without a detectable increase in interferon production, thereby arguing for direct interactions of LMP-1 with interferon regulatory elements in specific interferon stimulated genes (29). LMP-1 also potentially primes latently EBV infected cells for type I interferon production by a secondary infection (30). Chronic IFNα treatment of B cells may also encourage the transformed outgrowth of cells with the higher LMP-1 levels (31).
Quan et al. (7) do not experimentally address SLE directly and so set the stage for future studies to explore the interactions between SLE-associated environmental factors and interferon inducible gene expression changes. What is the role of EBV in these and other differences? Is the physiologic increase of interferon levels after EBV infection/reactivation sufficient to drive, relative to controls, the interferon signature of gene expression that has been reported in SLE? Are increased levels of interferon in SLE present before clinical disease onset and, if so, do these increases correlate with EBV seroconversion or reactivation? What influence on the natural history of disease do the immune complexes formed in lupus sera, which also induce interferon, have in relation to the interferon-inducing activity of the virus that Quan et al (7) describe? Of all of the ways type I interferon is induced and its consequences expressed in vivo, which of one or more of these are important in SLE pathogenesis (Figure 1)? Beyond SLE, do other autoimmune diseases with epidemiologic associations with EBV, such as multiple sclerosis and Sjögren's syndrome, have a differentially increased interferon production from pDCs or other cell types?
Knowing how EBV and other environmental factors influence the path toward pathogenic autoimmunity and clinical disease and how lupus disease risk loci interact with EBV will require additional study. Nevertheless, at this point, some features of the sequence of events from normal immune control to clinical autoimmunity with SLE as a consequence of EBV infection have become apparent (Figure 2). We can only hope that future work will validate and extend this scenario and fill the many steps involved with useful detail that presents an accurate conceptual construct of pathogenesis, fostering the development of important new diagnostics and therapeutics for SLE.
This work was supported by grants from the NIH (RR020143, AI083194, AI024717, AR042460,AI031584, RR015577, AI082714, AR053483, AR058554) and support as Kirkland Scholars and the Lou Kerr Chair in Biomedical Research (JAJ).
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.