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New Endeavors by Women
NEW partners with homeless women to create new futures. NEW transforms lives with housing, the development of life skills, and education and employment to end the cycle of homelessness.
Each year NEW helps more than 200 women and children move out of homelessness by providing housing, fostering the development of life skills, and promoting education and employment, to end the cycle of homelessness. There is a tremendous documented -- and growing -- need in the District of Columbia for the unique services that we provide. Homelessness affects more than 1,300 women in the District of Columbia. According to The Community Partnership for the Prevention of Homelessness (TCP), more than 15,000 people are homeless in Washington, DC over the course of a typical year, one of the highest rates of homelessness in the country.
On a single night in January 2015, there were 7,298 persons counted in the city's annual homeless census conducted by TCP. A total of 3,821 homeless single adults were counted in the 2014 homeless census in the District. Among them, 12% reported a history of substance abuse and 25% suffered from severe mental illness (including those with dual diagnosis); 8% reported chronic health problems; and, 13% were physically disabled. Among homeless adults in the District, 63% reported no income of any kind, while 14% of adults in families reported no income. Some 15% of single homeless adults reported experiencing domestic violence at some point in their lives. During the census there were 1,593 unaccompanied homeless adults and 66 persons in families in the District who met the federal definition of being "chronically homeless," defined as homeless persons with a disabling condition who have either been continuously homeless for a year or more, or who have four or more episodes of homelessness within the past three years.
NEW is guided by a mission to partner with homeless women to create new futures. We provide a nurturing environment so that women can recognize their worth. NEW transforms lives, by providing housing, fostering the development of life skills, and promoting education and employment, to end the cycle of homelessness.
New Endeavors by Women (NEW) was founded by a group of Washington, DC advocates for the homeless in July 1988 to provide urgently-needed housing and support to homeless women. Since opening our first women's-only transitional shelter, NEW has expanded to seven housing programs—two transitional programs and five permanent supportive programs. In addition to shelter, our programs provide an array of services to support women and children's social, health, educational and employment needs.
Our programs provide so much more than housing. We reconnect mothers and children torn apart by homelessness and poverty. We support women overcoming addiction to take control of their futures. We work closely with our residents to achieve their educational and employment goals as the stepping stones to better lives. Housing is just the beginning.
NEW operates seven housing programs: two transitional and five permanent supportive programs, including two housing programs exclusively for families. Each year we provide as many as 140 women and 80 or more children with: safe shelter; advocacy and case management; independent living skills education; substance abuse recovery assistance; parenting skills training; academic enrichment activities; employment and career counseling; strategies for obtaining and maintaining permanent affordable housing; on-site support groups and workshops; therapeutic and recreational activities; and, permanent housing.
We help homeless women and children achieve success in the midst of times for them that are usually filled with despair and chaos. A woman begins charting a path to create new futures on day one of her stay at a NEW with the development of her own individual service plan with goals for becoming self-sufficient. NEW case managers, education and employment specialists, and substance abuse counselors work with her to achieve her personal goals.
NEW's personal development supports focus on: building independence through an independent living skills program; education and job readiness; employment and career building. Through workshops and one-on-one sessions with NEW program staff, women pursue their goals and develop life management techniques, including budgeting time and finances. NEW encourages residents to improve their reading and math skills, and, if they do not have a high school diploma, to work towards taking the high school equivalency exam or enrolling in a job training program. Residents who wish to pursue higher education receive assistance with loan and grant applications, and choosing a school that best suits their needs.
NEW helps residents coordinate job training and employment searches. To foster long-term success, NEW focuses on career-oriented employment with advancement opportunities. NEW's Resident Resources Advocate works with each woman to identify her job skills, update her resume, write cover letters, and practice interview situations. The residents receive employment referrals or, if they are already employed, help in advancing in their current position. NEW also provides an in-house computer lab where women can develop a resume and search for jobs and housing.
NEW offers both short-term and long-term planning, housing and support to both women and children. We continue to believe that our greatest strength is the sum of the many people working together for NEW, from our board to our staff, donors and volunteers. Women – and their children – come to us, generally, with a plethora of issues that contribute to and result from their homelessness. No longer is the typical homeless woman likely to be somebody who suffered a single, causative incident, such as losing a job. Today's homeless women are beset by layers of challenges, including being under- or unemployed, unskilled, uneducated and suffering from addictions and/or mental health problems. Generational homelessness is more often an issue, leaving women who have never experienced stability of home, work and family. More and more youth are aging out of the foster care system or out of their own family's homelessness, leading to a population that is becoming ever younger with each passing year. Our program staff sifts through the layers and skillfully prioritizes individual case management strategies that will lead each woman and her family to create a new future; to climb out of chronic homelessness.
Since we opened our doors in 1988, we have served more than 3,500 women and more than 500 children. In 2015, our successes included: providing housing with support services to 206 people, including 127 women and 79 children; moving 86% of transitional residents to permanent housing; and, working closely with residents to improve job retention and employment stability, leading to increased earnings which averaged more than $11.00 per hour. Among our residents who are able to work, 80% secured jobs or enrolled in school. We also had 8 residents who enrolled in college courses.
We take pride in being responsible stewards of our donors' investments in our work. NEW's administrative and fundraising costs are less than 16%. That means that 84 cents of every dollar raised pays for direct services to the homeless women and children who reside in our housing programs.

subset: commoncrawl


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Architect: Park + Associates Pte Ltd
Client: Confidential
DESIGN AWARD (Residential Project)
House 24 is a two-generation house that captures the idyllic setting and views of a public park. The design turns the odd shape of the triangular site to its advantage by placing the main house mass on the long edge of the site, and a pavilion house block to exploit the full length of the pool. The spaces of these two part arrangement were nicely composed and scaled producing a delightful sense of arrival at the entrance; the whole obtaining spaces that are very liveable.
Main Contractor: Construkt Pte Ltd
C&S Consultant: CP Lim & Partners LLP


text: The Barreado is a typical dish from Paraná state in South Brazil, specially found in Morretes near Antonina in Paranaguá Bay. Its origin is a rite of Azorean people who came in the 18th century. The Barreado consists of a stewed meat, served with rice and farinha de mandioca. The secret is in preparing the in the clay pot for about twenty hours – enough to shred all the meat. Once cooked, the meat fibers are released resulting in a thick and tasty broth. To maintain the flavour of meat, you need to seal the pan with a batter of flour and water, a clay prepared to keep the steam inside the pot.


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The Hakko dual-power soldering iron is a light-duty soldering iron with optional power. The user can increase the power from 20-watts to 130-watts with the press of a button. This iron is ideal for soldering applications that may need a boost of power for occasional heavy-duty soldering application.
California residents: see Proposition 65 information
- 20-Watt normal power
- Boost button increases power to 130-Watt
- Heats up to 440° F (20-Watt)
- Heats up to 630° F (130-Watt)
- Pen configuration/style soldering iron
- Click here for more information on Electronic Recycling Programs


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Dear Victor,
Is there any way that you are aware to make waffles that are good for you? I weigh 400 pounds and I am on a diet to become more healthy but....I love waffles. Can you help?
400 lbs? Damn when was the last time you seen your lower parts? I think you should sue someone over this issue as suing has become the way of life in good old U.S. of A.
Waffles are good but damn bro ya need think about your heart. Just because something is good it don't mean it's good FOR ya. Every time ya go to eat THINK of yourself naked in the shower. That may help slow ya down abit.
1. Why is the English alphabet in the order it is in? Is it so people can say, LMNOP, and think it's funny?, or did congress have something to do with it those fuckers. 2. Shouldn't they call it not quite dead yet row?
#1 Why ask why? I mean when you take a shit do you ask why you look at the toilet paper with each wipe? Maybe you should ask how you can help homeless people, or feed someone. Sure seems you've alot of time for wondering stuff. # 2 Yeah good point maybe it should be called "not quite dead yet row". But aren't we all really on death row? Just because a person is here is there any promise you'll out live me?
Drink a beer for me and have a joint.


text: Happy New Year from the knack! 3:00 am May this year bring you joy, success and peace.Thank you for your continuing support of the knack. I couldn't do any of this without you!Warmest wishes, many thanks and big hugs,StephanieStephanie DickisonPublisher & Editor - the knack Share This Post Share on Facebook Share on Twitter Pin this Post Tags: Newer Post Older Post Stephanie Dickison Stephanie Dickison is a journalist, editor and author with a knack for stylish + modern solutions for your life. You Might Also Like 0 comments


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Rep. Nick King: "I was not always opposed to Right to Work. But, as I knocked on doors, and talked to the people I represent, I learned where their hearts are and where their minds are."
The Missouri Ethics Commission released lobbyist gift data for June 2015 today. Here are you updated rankings of gift takers in the House and Senate, January 2015-June 2015. Rep. Tom Flanigan of Carthage tops all takers for the year.
Rep. Caleb Rowden's stance on lobbyist gifts is as unclear as it's ever been. As a freshman lawmaker he led the way in gift taking, but as his 2014 re-election race approached, Rowden back-tracked, promising to be better and support a ban on gifts. Low and behold this year he's back to his old ways.
In a recent newsletter, Rep. Bill Lant (R-Pineville) proclaimed the recently released Planned Parenthood videos worse than anything Nazis did.
He wrote:
"I grew up during the 50's and 60's when the Nazi trials were still being held and there was no testimony I heard that was more horrible than what I heard last week."
Rep. Jay Barnes (R-Jefferson City) wrote about Planned Parenthood recently, comparing the organization's leaders to slave holders.
In an interview with KMOX, Rex Sinquefield said raising the minimum wage is an "injustice" on par with racist police practices.
As Jefferson City politicians head off to ALEC's 2015 Junket in San Diego, we can't help but wonder who is picking up the tab.
Governor Nixon signed the first bill advancing sexual health education in over a decade for Missouri. The bill, HB 501, was sponsored by Rep. Genise Montecillo (D-St. Louis) and requires information about internet safety and the dangers of sexting to be added to sex education law.
The Dent County Commission, Darrell Skiles, Gary Larson and Dennis Purcell, unanimously voted to observe a year of mourning in light of the SCOTUS marriage equality ruling.
Sen. McCaskill agrees with Gov. Nixon that it is outrageous LGBT Missourians can legally be discriminated against.
Progress Missouri
Our mission is to provide a strong, credible voice to advance progressive solutions to critical community problems. But we don't do that on our own – we work as a communications team for the entire progressive community.
We're a proud member of the ProgressNow network of 20+ state affiliates from around the country, each working to advance the work of their respective partners..


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Muscat & Hajar Mountains
Muscat Travel Blog› entry 1 of 1 › view all entries
Having little to do during the Muslim EID holidays, we decided to visit Muscat, the capital of Sultanate of Oman. As it was a spontaneous decision, we were extremely disappointed not to be able to any flights to Muscat at short notice. In the end, we decided to drive to Muscat, which turned out to be a good decision as it gave us the flexibility to drive to the Hajar Mountains. We clocked about 1600 km for the round trip from Dubai to Muscat and to Jebel Shams (the highest mountain in the magnificent Hajar Mountain range).
Oman is the second largest country in Arabia with cities lining up the coast facing the Arabian Gulf, imposing mountain range spanning from east to west in the northern part of the country and extensive deserts on the inland.
Highly recommended hotel to stay in Muscat is the Crowne Plaza but only in the sea facing rooms as the view is fantastic with the sea just in front and the distant Hajar Mountains on the horizon. An interesting hotel to visit or stay in Muscat is the Al Bustan Palace Intercontinental. It is every bit of an Arabian palace with its unique architecture and mosque-like lobby. Really the epitome of five star finery!
From Muscat, we drove to Jebel Shams and the Hajar Mountains range. Along the way, we came across the abandoned Persian village of Ghul. From a distance, the ruins were a pretty sight sandwiched between the irrigated farm land at the bottom and the bare mountains to the back.
We also visited Nizwa which was another 200km from Muscat. There was another ruins but not as impressive as the ruins of Ghul. The Nizwa fort was one of the main attraction of this town.
The most pleasant surprise from this trip was experiencing the Omani hospitality in a town called Saham while driving back to Dubai. We pulled up in front of a house to ask an Omani man for directions and were invited to the house for tea. Apparently they were just as curious about us as we were about the Omanis. Soon his five kids, two wives, father, mother, uncle and some other relatives all came out to greet us.
Although language was a barrier with the elders and the youngsters, their hospitality was nevertheless felt. They also insisted that we stay for lunch. Although we were a bit hesitant initially about imposing on them, we were actually honored and happy with the invitation as it was a great way to experience the Omani culture first hand.
Within half an hour, a feast appeared in front of us, placed neatly on the carpet in front of us. The main dish of lamb was stunning, even through I am not a mutton fan because of the smell. For the first time, I tasted really delicious and succulent mutton that was cooked in the traditional way with the meat being cooked briefly, then wrapped in foil and buried underground for several hours. It was so good that I had a second helping!
What an unforgettable experience with the Omani hospitability.


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It's that time again
Loyal fans flock to Wrigley
For Opening Day
Perhaps in recognition that the product on the field might not be very good, the Cubs have been reminding us all winter that it's going to be the "Party of The Century" at Wrigley Field. That's because it's been 100 years since the first ballpark was built at Clark and Addison.
It wasn't called Wrigley Field, and the Cubs weren't playing there. But it was a ballpark. So the Cubs marketing department has their theme for the season. But don't be too cynical - Wrigley is a classic ballpark (please don't call it a stadium) and if fans are honest, they'll admit it's one of the reasons they came to love (or at least be fans of) the Cubs. There's nothing like a summer afternoon - or a cold April afternoon - at the Friendly Confines.
It's a tradition
Wrigley, the Cubs, my daughter
Freezing our butts off
I had been to a few opening days through the years, but it didn't become a habit until about 10 years ago when I cursed my youngest daughter with Cubs fandom. We started making sure Opening Day was included with our ticket purchases for the season, and after the Cubs Convention each winter we'd look forward to that cold day in April when we'd see live baseball again.
Now we've got season tickets, and the first rule for my "partners", who help to pay for this extravagance, is that I get the tickets for Opening Day. It doesn't matter how cold it is (we'll layer up) and it doesn't matter how good we expect the Cubs to play (there's always next year). Baseball - and especially Opening Day - is all about tradition.
And hoping that the Cubs will be victorious and the "W" flag will fly.
And tradition.
Don't miss any of the haiku party this summer. Type your email address in the box and click the "create subscription" button. My list is completely spam free, and you can opt out at any time.
Filed under: Cubs
Tags: Opening Day


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Happy hump day! So glad it's almost Friday! We've got family coming into town this weekend and I can hardly wait for them to get here!! I've been scrambling around to get all the last minute details together before their arrival.
The weather has continued to be so fab here, you won't catch me complaining one bit! I'm so glad I can still wear dresses like this with no tights. Adding this vest and booties to my outfit gives it a bit more of a Fall vibe, while letting me stay cool in the warm climate. What do you think?
xo | dré
dress | H&M
vest | H&M
booties | Sam Edelman
bag | Marc by Marc Jacobs
sunglasses | vendor at Venice Beach


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Toyota of Puyallup
Review for Toyota of Puyallup
Dereck K. on 09/15/2011
Spoke with Genevieve. She said she was not completely satisfied with her overall service experience because she originally came in for an oil change and had a bad service experience. She was treat disrespectfully and she had a hard time because her husband told her to go there while he is deployed in Afghanistan. She was satisfied with the business when they changed her radio for her. She was satisfied when she talked to the service manager. She rated her overall experience with the business a 3 instead of a 5 because of the reasons already stated. She was not completely satisfied with the quality of service work performed on her vehicle and she would not recommend this business for service because of the reasons already stated.
Category: Service
Review Created: 09/15/2011


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All Android applications categories
Tyra Lynne Banks (b. 4 December 1973) is an American model, media personality, actress and singer. Born in Inglewood, California, Tyra began with a modeling career when she was in 11th grade. She later went to Paris to do some catwalk modeling and impressed the designers to such an extent that they booked her for twenty-five shows – a sort of record for a newcomer. She has worked for all major fashion and advertising giants and she has appeared on the covers of famous high-fashion magazines like Vogue, Elle, Cosmopolitan and Harper's Bazaar. Tyra is the first African-American woman to appear on the covers of GQ and the Sports Illustrated Swimsuit Issue.
In 2005, Banks back off move away from modeling to devote full time on her television and firm career. In television, she has appeared in programs like The Fresh Prince of Bel-Air (1993) Felicity, Just Shoot Me! (1999) as lead actress as well as a host in America's Next Top Model (2003-present) and The Tyra Banks Show (2005-10), besides many other programs. Bank's filmography includes Higher Learning (1995), Coyote Ugly (2000) and Halloween Resurrection (2002). Banks has also appeared in several music videos with many famous singers.
6Sense Technologies has launched such a talented personality, Tyra Banks, with her high quality rare photos in an ANDROID application.
You do not need to connect to Internet or Wi-Fi to access this app. Isn't it great!
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On 16 February 2017 at 11:31, Piotr Ożarowski <pi...@debian.org> wrote: > Are you guys seriously considering dgit to replace anything other than > dput in DPMT? I'd rather go back to svn-buildpackage than use something > that will not allow me (f.e. as sponsor) to review before uploading!
One can totally review before uploading with dgit. dgit takes ownership/syncing of your dgit/* heads. One can totally push master; review it; fix it up; push more; and then as a sponsor if you are happy to publish master one invokes dgit push to update the dgit/* branches & execute dput with a source matching the git tree. Is this the workflow you want? dgit doesn't impose anything what one does with master branch, or any other branch names you want. -- Regards, Dimitri.


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We've chosen Pledge Music to raise the funds necessary to record our new album.
By making a pledge, you will facilitate the recording, mixing, and mastering of our music and also get a behind the scenes look into the process exclusive only to our pledgers. There are lots more benefits and rewards for additional donations that you must check out on our Pledge Music page – PLUS, don't forget, with the minimum donation ($10-$15) you will be pre-ordering the NEXT GIRLS & BOYS ALBUM!!
We are excited to share our journey with you every step of the way!! Every pledge gets us that much closer to our goal. We look forward to getting more of Girls & Boys music into your hands. Our music has taken us quite the distance so far… and we're not done yet!! We truly believe in the communal aspect of music and understand that without you we would not be where we are now. Join us in making the album of our dreams!! With love and thanks, Girls & Boys


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You may be thinking, um, isn't all ketchup pretty much the same? My response to that is no, it is not the same. Annie's Naturals rocks, is certified gluten free and has the best flavor around.
So, anyway, I don't have much more to say about this, so here's what the packaging looks like.


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We care, we inform, we listen and we go as far as we need to in order to fulfil your dream.
Wildlife Safaris and Cultural Tours KZN
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Safaris ( 2 to 7 Days )
2 Day Safari "Big 5" Wildlife at Hluhluwe/ Umfolozi Game Reserve
2 Day Drakensberg & Sani Pass/Lesotho Adventure
3 Day Rejuvenate Your Soul ( Drakensberg & Sani Pass/Lesotho )
SAFARI 'Big 5' 3 Day Grassroots Experience
7 Day - SAFARI & DRAKENSBERG/SANI PASS - Kingdom of the Zulu
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What precautions should be taken against malaria?
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What precautions should you take when visiting Zululand?
What they dont tell you.
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Jim Breuer: Heavy Metal Comedy Trailer (2002)
With "Goat Boy" and "The Joe Pesci Show" skits, Jim Breuer rose to fame during his short stint on Saturday Night Live. After leaving the show under cloudy circumstances, Breuer set out on the road. This concert film captures his high-energy performance at the Irving Plaza in New York City. He tackles topics like the band AC/DC and pregnancy, and tells a story about how he had a very bad night involving too much tequila at a party.
Watch the official Jim Breuer: Heavy Metal Comedy 2002 trailer in HD below or find more Jim Breuer: Heavy Metal Comedy videos on Vidimovie.


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Hey all!
I've been wanting to write this for a while, but was too lazy to do it.
This is a very early Christmas present for love AnImE GiRl love.
Enjoy! Also, Inheritance never happened, this is after Brisingr.
Disclaimer: Don't own it, so don't rub it in.
Eragon yelped in pain as he felt cold metal slice across his chest. Instinctively, he lashed out with his sword, instantly decapitating his attacker.
"Saphira!" he called out, as he could not communicate through his mind without being detected by an enemy spell caster.
He, the elves and the Varden were currently trying to break Lord Garvic's (1) fort. Originally it had seemed an easy task, but out of nowhere a team of Galbatorix's chief magicians had ambushed them.
"Shadeslayer! Brightscales!"
Eragon spun round at the shout, and sprinted towards Blodhgarm. (A/N: That is how you spell it, right?)
"Yes?" he asked, once he and Saphira had arrived.
"We need to get you and Brightscales out of here!" The catlike elf was obviously distressed.
"What?" said Eragon in disbelief, "I can't leave! You need us-" the elf cut him off.
"No, you don't understand, Shadeslayer: Galbatorix is coming! As powerful as you are, you are not ready to fight him!"
"But I- What?" Eragon wasn't sure he had heard right.
"Galbatorix is coming! You need to get away!"
"I've been practising! I can do non-verbal spells now, and-"
"No arguments Eragon!" Arya shouted, before launching into a spell, "přepravy tento řadič prvků a jeho měřítka zvíře do jiné dimenze!"
"What're you-" he was cut off by the twelve other elves joining her chant.
"Dovolte nám pomáhají naše sestra ve své snaze zachránit poslední volné jezdce!"
Eragon felt a pulling sensation deep inside his gut, and distantly he heard Saphira roaring in panic before sinking into impenetrable blackness...
Ooh, I left a cliffie! (bad writer)
Please review! Reviews make the world go round! (well, my world anyway...) so press the pretty blue button and make it spin like a drunken sailor!


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|Home | About | Journals | Submit | Contact Us | Français
Benign prostate and prostatic adenocarcinoma contain rare quiescent neuroendocrine cells while small cell neuroendocrine carcinoma (SCNC), a variant form of prostate cancer, contains highly proliferative neuroendocrine tumor cells. We provide evidence that IL-8-CXCR2-P53 pathway keeps the NE cells in a quiescent state normally. P53 mutation inactivates this pathway, resulting in hyper-proliferation and aggressive behavior of the NE cells in SCNC. Therefore, we have identified potential cells of origin and a molecular target for prostatic SCNC that are different from those of adenocarcinoma, which explains SCNC′s distinct biology and the clinical observation that it does not respond to hormonal therapy.
Prostate cancer is a major health risk for men in Western countries as it is the most common malignancy and the second leading cause of cancer-related deaths. In some countries where prostate cancer is traditionally uncommon such as China, the incidence of prostate cancer has also shown a dramatic increase in recent years.
Low grade, organ-confined prostate cancers are curable by surgery or radiation therapy. For patients with recurrent or metastatic prostate cancer, hormonal therapy, by inhibiting androgen production and/or blocking androgen receptor (AR) function, is the treatment of choice. Unfortunately, hormonal therapy is not curative and the cancer nearly always recurs after an initial period of response and inevitably progresses to the castration resistant stage. Newer agents have been developed to inhibit intratumoral androgen production or more effectively block AR function, but resistance occurs quickly. In this article, we will focus our discussion on cellular heterogeneity of human prostate cancer and molecular mechanisms responsible for the development of small cell neuroendocrine carcinoma (SCNC), a lethal form of prostate cancer often seen in patients who have received hormonal therapy.
Prostate is a glandular organ in which the epithelial cells form glands or ducts. Under the light microscope, two types of epithelial cells are easily identifiable in the prostate: (i) secretory cells (or luminal cells) that produce secreted proteins including prostate-specific antigen (PSA); and (ii) basal cells that likely function as reserve cells. There is a third, minor epithelial cell type called neuroendocrine (NE) cells that are scattered among the basal and luminal cells (Figure 1, left panel) and constitute ~1% of the total epithelial cell population.1,2,3 The NE cells can be identified by electron microscopy showing distinct ultrastructural morphology and intracytoplasmic dense-core secretory granules. More commonly, they are detected by immunohistochemistry (IHC) with antibodies against NE markers such as Chromogranin A or Synaptophysin with the former being more sensitive and specific.1,2,3 In mice, NE cells are concentrated around the proximal urethra while not commonly seen in the various lobes of the prostate. Since NE cells are present in every single benign human prostate, they are presumed to play important roles in prostate development or function. However, little experimental evidence exists that provides significant insights into their function.
Prostatic adenocarcinoma is the most common malignant tumor type in human prostate, accounting for well over 90% of all prostate cancers. Histologically, it is characterized by uncontrolled proliferation of malignant secretory-type tumor cells and a lack of basal cells. Interestingly, every single case of prostatic adenocarcinoma also contains scattered NE tumor cells (Figure 1, middle panel) and the number of NE cells varies from case to case. On average, NE cells account for no more than 1% of all tumor cells, although rare cases contain abundant NE cells. It remains controversial whether the number of NE tumor cells correlates with tumor grade and stage. The main difficulty in resolving this issue is that IHC staining is required to highlight the unevenly distributed NE cells and it is impractical to stain the entire tumor to accurately count all NE cells. On the other hand, it is widely accepted that hormonal therapy for adenocarcinoma leads to increased NE tumor cells, and abundant NE tumor cells are seen in most castration resistant prostate cancers (Figure 1, right panel). The mechanism for the increase in the NE cell component of adenocarcinoma after hormonal therapy is unclear. Unlike the bulk, secretory type cancer cells, NE tumor cells do not express AR4 and are independent of androgen. As a result, while the bulk tumor cells undergo apoptosis after androgen ablation, the NE tumor cells continue to survive and their relative percentage in the tumor increases (Figure 2). There has also been evidence that the normally quiescent NE tumor cells may proliferate under androgen-deprived conditions,5 so it is possible that there is also an expansion of this cell type resulting in an increase in the absolute number of NE tumor cells.
The consequence of increased NE tumor cells after hormonal therapy is of significant research interest. Experimental evidence has been presented showing that NE tumor cells can promote androgen-independent growth and tumorigenesis,6 and invasion and metastasis of prostate cancer cells,7 likely through their secreted products.8,9 Studies over the years have shown that NE cells secret biogenic amines, neuropeptides and cytokines, while the bulk, non-NE tumor cells express receptors for many of the NE cell products.1,2,3 Therefore, it has been hypothesized that hormonal therapy for adenocarcinoma leads to increased NE tumor cells, which establish paracrine networks within the tumor and stimulate proliferation, invasion and metastasis of the bulk, non-NE tumor cells in the androgen-deprived environment, contributing to the progression of the tumor to the castration resistant stage (Figure 2). Hence, NE tumor cells may be important therapeutic targets.
LNCaP is a classic prostate cancer cell line that possesses the important characteristics of secretory type adenocarcinoma cells. They express AR and secret PSA and their proliferation is dependent on continued presence of androgen. Withdrawal of androgen in the culture media, usually by replacing normal fetal bovine serum with charcoal-stripped fetal bovine serum, leads to growth arrest and eventual acquisition of NE phenotype in LNCaP cells,10 including elongation of cell bodies mimicking neuronal cells and expression of NE markers such as neuron-specific enolase. Dr Kung's group at UC Davis showed that adding IL-8 to androgen-deprived media promoted proliferation and migration of LNCaP cells, suggesting that IL-8 may be one of the factors contributing to the progression of adenocarcinoma to the castration resistant state.11 We were intrigued by this finding and studied the source of IL-8 in human prostatic adenocarcinoma. We stained adenocarcinoma tissue with an antibody against IL-8 and interestingly, only scattered tumor cells stained strongly, while the vast majority of the tumor cells were entirely negative. By staining serial sections of adenocarcinoma tissue with anti-IL-8 and anti-Chromogranin A antibodies, respectively, we confirmed that NE tumors cells are the only tumor cells that produce IL-8. There are two known receptors for IL-8 in human tissues, CXCR1 and CXCR2. While benign secretory type epithelial cells of the prostate do not express CXCR1, this receptor is overexpressed in adenocarcinoma cells. It is therefore reasonable to propose that a paracrine activation of CXCR1 (expressed by bulk tumor cells) by IL-8 (secreted by NE tumor cells) may contribute to androgen-independent proliferation of prostate cancer in patients treated with hormonal therapy.
Another receptor for IL-8 is CXCR2 which shares significant homology with CXCR1. We also immunohistochemically stained adenocarcinoma tissue for the expression of CXCR2 and our results demonstrated that similar to IL-8, CXCR2 was exclusively expressed in the NE tumor cells of adenocarcinoma. Since NE cells in adenocarcinoma express IL-8 and its receptor CXCR2, we hypothesized that there is an autocrine interaction which may be critical for certain aspects of the NE cell biology.12
In addition to being negative for AR and PSA, an important feature of NE cells in adenocarcinoma is that they are normally quiescent,4 which is unique among the cancer cells. The molecular mechanism that maintains the NE tumor cells in a quiescent state was unknown. A few years after our finding that NE cells express IL-8 and CXCR2, another group reported that fibroblasts that undergo senescence overexpress IL-8 and CXCR2 and the autocrine action is critical for the induction of senescence. The authors also showed that the induction of cellular senescence by IL-8-CXCR2 signaling is mediated by P53.13 We reasoned that a similar mechanism may also exist in NE cells, that is, IL-8-CXCR2 signaling may keep NE cells of benign prostate and adenocarcinoma in a quiescent state. We further hypothesized that P53 may similarly mediate IL-8/CXCR2 signaling and the IL-8/CXCR2/P53 signaling pathway may represent a major growth inhibitory pathway of the NE cells.
While the above hypothesis is interesting in terms of understanding the molecular physiology of the NE cells, it has important clinical implications as well. Clinically, a small percentage of prostate cancers is classified as SCNC in which the tumor cells are all NE cells (Figure 3). In contrast to the NE cells in benign prostate and adenocarcinoma that are normally quiescent, NE tumor cells in SCNC are highly proliferative and aggressive, often leading to widespread metastasis and death within months of the initial diagnosis. SCNC can arise de novo in men without a history of adenocarcinoma but more commonly, it occurs as a recurrent tumor in men with a history of adenocarcinoma and treated with hormonal therapy. SCNC can occur in a pure form, but it is often found in a mixed tumor where it coexists with conventional adenocarcinoma (Figure 3, upper left). In contrast to prostatic adenocarcinoma which forms glands, SCNC has a solid, sheet-like growth pattern but no glandular formation. Tumor cells are small, with fine chromatin pattern, scant cytoplasm and nuclear molding. Mitotic figures, crush artifact and tumor necrosis are frequent findings14,15,16 (Figure 3, upper right).
The reported incidence of prostatic SCNC is low (~1% of all prostate cancers), but this disease is likely significantly underdiagnosed.17 A main reason is that patients with known prostatic adenocarcinoma whose diseases have become advanced and widely metastatic on imaging studies usually do not undergo tissue diagnosis. Another reason is that SCNC is morphologically very different from prostatic adenocarcinoma and often metastasizes to visceral organs, while adenocarcinoma typically involves bone and lymph nodes. As a result, a connection between metastatic SCNC and the original prostatic adenocarcinoma may not always be established. On the other hand, accurate diagnosis of SCNC is important as such tumors do not respond to hormonal therapy targeting the AR signaling pathway18 which produces a therapeutic response, at least initially, in nearly all cases of prostatic adenocarcinoma.19
The molecular mechanism for prostatic SCNC was unclear, although the phenomenon of prostatic adenocarcinoma recurring as SCNC had been well recognized clinically. Because IL-8/CXCR2/P53 pathway may keep the NE cells in a quiescent state, we hypothesized that inactivation of this pathway may remove a major growth inhibitory mechanism, leading to rapid proliferation and aggressive behavior of the malignant NE cells and resulting in the development of SCNC.20 This hypothesis has two important components: (i) The cell of origin of prostatic SCNC may be the NE cells of either benign prostate or prostatic adenocarcinoma, with the latter more likely; and (ii) P53 mutation may be a critical molecular event for the development of SCNC.
To test this hypothesis, we developed stable clones of LNCaP cells that express high levels of CXCR2 (LNCaP/CXCR2 cells). We examined transcriptional response of LNCaP/CXCR2 cells to IL-8 stimulation and found that numerous genes were up- or downregulated after activation of CXCR2. Functional gene family analysis showed that among the genes whose expression increased significantly in response to IL-8 stimulation were those controlling the G1/S and G2/M transition check points, while many genes downregulated after IL-8 stimulation are involved in cell morphology and development. Importantly, the expression of many genes involved in P53 signaling was significantly altered after IL-8 stimulation.20
In support of our hypothesis, IL-8 inhibited the proliferation of LNCaP/CXCR2 cells but not the parental LNCaP cells. In addition, P53 was required for the growth-inhibitory function of CXCR2 signaling, as knockdown of P53 by siRNA abolished the growth inhibition of LNCaP/CXCR2 cells by IL-8.20
The above observations were confirmed with another commonly used prostate cancer cell line PC3. Our group has recently shown that PC3 cells possess features of prostatic SCNC in that these cells are negative for luminal differentiation markers AR and PSA but positive for NE markers.21 Similar to NE cells in benign prostate and prostatic adenocarcinoma, PC3 cells express IL-822 and CXCR2.23 Contrary to NE cells in benign prostate and prostatic adenocarcinoma, PC3 cells are highly proliferative and aggressive which is similar to NE tumor cells of human prostatic SCNC. We hypothesized that the loss of the growth inhibitory function of the IL-8/CXCR2/p53 pathway may be responsible for the rapid proliferation and aggressive behavior of PC3 cells. Consistent with our hypothesis, it has been reported that PC3 cells, unlike LNCaP cells, contain a p53 mutation.24 When we re-introduced wild-type P53 into PC3 cells, IL-8 treatment inhibited growth of PC3 cells.20
To provide further evidence that P53 mutation is a critical molecular event in the pathogenesis of prostatic SCNC, we performed IHC staining of benign human prostate, prostatic adenocarcinoma and prostatic SCNC. Positive nuclear staining for P53 was used as a surrogate marker for P53 mutation since it is well known that mutant P53 has prolonged half-life and the P53 protein becomes detectable in the nucleus by IHC staining. We used a tissue microarray containing adenocarcinoma and benign prostate tissue from 150 cases and adjacent sections were stained with antibodies against Chromogranin A and P53, respectively. In both types of tissue, the scattered NE cells and the scattered P53-positive cells did not overlap, suggesting that in benign prostate and prostatic adenocarcinoma, the NE cells likely have wild-type p53. In contrast, when regular sections from 31 cases of prostatic SCNC were stained for P53, strong and diffuse nuclear positivity was observed in the majority of the cases, strongly suggesting frequent P53 mutation in such tumors. We obtained formalin-fixed, paraffin-embedded tissue from seven cases of prostatic SCNC and extracted genomic DNA from them. Sequencing of exons 5–10 showed that five out of seven tumor samples contained an identical allele of a missense transition converting G to A at position 747, changing the negatively charged aspartic acid to hydrophilic amino-acid asparagine at amino acid 184, supporting our hypothesis that P53 mutation is likely a critical event in the pathogenesis of prostatic SCNC.
The results of the above studies reveal the likely cell of origin and the molecular basis of prostatic SCNC. NE cells may play important roles in benign prostate and treatment naive adenocarcinoma, although little detail is known. Because these cells are AR negative and androgen-independent, they are resistant to hormonal therapy which induces apoptosis of the bulk, non-NE tumor cells. Besides causing a relative increase in the proportion of NE cells in the tumor, hormonal therapy may also induce proliferation of the normally quiescent NE cells,5 resulting in an increase in the absolute number of NE cells in the tumor. We propose that during the process, a P53 mutation occurs in the NE cells, inactivating the growth-inhibitory IL-8/CXCR2/P53 pathway, resulting in rapid proliferation and aggressive behavior of the NE cells and the development of SCNC20 (Figure 4). In fact, IL-8/CXCR2 signaling may become growth-stimulating in the absence of functional P53.20 In our opinion, SCNC is an underdiagnosed entity for reasons discussed above. With the advent of new drugs that represent super-AR blockers (e.g., MDV3100) or inhibitors of intratumoral androgen synthesis (e.g., abiraterone), we only expect an even higher incidence of prostatic SCNC. Because the NE tumor cells do not express AR and are independent of androgen, SCNC does not respond to therapies targeting AR pathway. Therefore, it is considered a disease that is generally lethal without effective treatment options.25
The above hypothesis, although interesting and potentially very important, still presents an incomplete picture of SCNC For example, it remains unclear if SCNC only arises from NE tumor cells of adenocarcinoma, or the NE cells in benign prostate can also be cells of origin for SCNC. Most commonly, prostatic SCNC occurs in patients with a history of adenocarcinoma treated with hormonal therapy, suggesting NE tumor cells of adenocarcinoma as the likely cell of origin. This notion is supported by pathological observation that prostatic SCNC often coexists with a conventional prostatic adenocarcinoma (Figure 3, upper left) and pure SCNC is very rare. However, clinically, some patients without a history of adenocarcinoma can present with prostatic SCNC, suggesting that NE cells in benign prostate can also give rise to SCNC. The caveat is that these patients may have had a pre-existing undiagnosed adenocarcinoma which has been completely replaced by the rapidly proliferating tumor cells of SCNC.
Our observations provide insights into the mechanism of pathogenesis of the well-known transgenic adenocarcinoma of mouse prostate (TRAMP) model. This model was established by overexpression of SV40 early genes under the control of the AR-responsive probasin promoter.26 It had been known for a long time that TRAMP tumors resemble human prostatic SCNC morphologically, but a satisfactory explanation for the unusual histology had not been provided. We believe that although AR is considered a marker of prostate luminal differentiation, it is possible that a low level of AR is present in NE cells at some point of mouse prostate development and is sufficient to activate the probasin promoter. We hypothesize that in these animals, inactivation of P53 in NE cells of the prostate leads to malignant transformation and rapid proliferation of NE cells, resulting in the development of a malignant tumor with abundant NE tumor cells mimicking human prostatic SCNC.
SV40 T antigen inactivates both P53 and Rb in TRAMP tumors. Nikitin's group27 has developed a p53−/−Rb−/− double knockout mouse model in which probasin promoter was used to drive the expression of the Cre recombinase, and the resulting tumors show similar SCNC morphology. Their study showed that both P53 and Rb need to be inactivated in order for invasive tumors to develop. Therefore, it remains unclear if inactivation of Rb as well as p53 in NE cells is required for the development of prostatic SCNC in human patients.
Notably, in both TRAMP and p53−/−Rb−/− double knockout models, there are also areas of glandular formation resembling adenocarcinoma, which probably results from inactivation of p53 and/or Rb in the luminal epithelial cells. In most of the TRAMP tumors we have examined, NE tumor cells predominate, likely reflecting the highly proliferative nature of the malignant NE tumor cells which can easily obliterate the adenocarcinoma areas.
Another important issue is the nature of p53 mutation. We observed the same mutation in five of seven SCNC samples sequenced, but this is unlikely the only mutation for all such tumors. de Marzo's group28 reported positive nuclear staining for p53 and a p53 mutation in a case of SCNC intermixed with adenocarcinoma. The p53 mutation discovered in their study differs from the one identified in our cases, suggesting that a variety of p53 mutations may be found if a large number of SCNCs are sequenced.
Prostatic SCNC has gained increased recognition as an important disease entity and two recent studies have used powerful sequencing technologies for such tumors. Rubin's group29 discovered that a large number of prostatic SCNCs have significant overexpression and gene amplification of Aurora kinase A and MYCN and the former may serve as a potentially useful therapeutic target Collins's group30 found REST transcriptional complex to be critical in the development of prostatic SCNC Such diverse findings have undoubtedly increased our understanding of this important disease and collectively may eventually help to find novel therapies.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


text:
Students who acquire large debts putting themselves through school are unlikely to think about changing society, Chomsky suggested. "When you trap people in a system of debt . they can't afford the time to think." Tuition fee increases are a "disciplinary technique," and, by the time students graduate, they are not only loaded with debt, but have also internalized the "disciplinarian culture." This makes them efficient components of the consumer economy.
Така казва Ноам Чомски.


text:
May 1, 2015 to May 31, 2015
- ITU Campus
Food Drive Details:
Students should drop off donations in the Student Success Center, Department of Accounting Services, and Student Information Desk. You can choose from the list of suggested items below, or your own non-perishable items*.
2. Tuna and canned meat
3. Peanut butter
4. Canned foods with pop-top lids
5. Low-sugar cereals
6. 100% fruit juices in single serving boxes
7. Canned fruit packed in juice
8. Canned vegetables (low salt)
9. Pop-Top Tuna
10. 100% Fruit Rolls
11. Raisins
12. Graham Crackers
13. Unsweetened Applesauce
14. Cheese and Crackers
15. Fruit Cups
16. Low-sugar Cereal Bowls
17. Pretzels
18. 100% Fruit Juice Boxes
19. Granola Bars (without peanuts)
*We request that you do not donate bulk quantities of rice, flour, or sugar. Although we appreciate and can utilize every donation we receive, the Food Bank does not have the repackaging facilities needed to properly distribute such items. Please contact the Donor Hotline at 1-866-234-3663 for details.
Students will be working alongside the Student Success Center to compete with other ITU departments for a prize!
If you are interested in volunteering opportunities or simply want to know more, please visit the Second Harvest Food Bank's website at http://www.shfb.org.


text:
Ok, I'm sure everyone gets those weeks that just seem to drag on. The past few have seemed to be the longest I've ever had.
We left home to drive up to Auckland for a week on Sunday the 19th October, my cat was at her favourite cattery for the duration. On the way up was pretty uneventful.
Just your usual long drive from Palmy to Auckland. We did get some idiot try and pass when the signs clearly stated "Do not Pass on Painted Median" Well, no wonder the car in front was going to turn right in the turning lane when this moron came screaming up the side of us and just about collected the car turning. If I hadn't been driving I would've whipped out the camera and taken a photo. Anyway, he didn't learn. I was sitting around 105kph when who should come flying past us. The same idiot passing on a corner no less, do some people need to kill themselves or others before they learn. Maybe they just never learn I dunno.
Got to Auckland that evening and once we were settled in to where we were staying, we decided to order Pizza Hut for dinner. The weather was reasonable so we sat outside and ate.
We had an appointment at 8am the following morning (Monday) so after a long drive I was pretty much ready for bed by 9pm. I didn't think I was going to be able to get up early enough but I managed it.
The week was pretty good, weather wise but due to the circumstances of why we were there (which I won't go into at this time) I spent most of it inside or running up and down a bloody hill. I even managed to kill a pair of boots which I have to get the sole re-attached.


text:
Purdue seems to have made quite an early impression on Dorian Bryant, enough so that the Boilermakers can probably be considered legitimate contenders for the star New Jersey athlete.
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text:
Submission details
DR650SE`s SuperPi - 32M score - Apprentice League
9min 40sec 636ms with Intel Core i7 920XM at 3989MHz
Ranking position
WR Rank:
Not a world record...
Global rank:
3271st out of 4000
Core i7 920XM rank:
2nd out of 5
Points earned
Global Points (UGP) 3271st
0.0 Points
Hardware Points (UHP) 2nd using Core i7 920XM
1.5 Points
Global Team Power Points (GTPP) Not Tech|Inferno's best submission.
0.0 Points
Hardware Team Power Points (HTPP) Not Tech|Inferno's best Core i7 920XM submission.
0.0 Points
Hardware details
CPU details
- Model: Intel Core i7 920XM 'Clarksfield'
- Cooling: Air (Stock)
- Speed: 3,989MHz (+99.45%)
Memory details
- Product: HyperX
- Cooling: Air (Stock)
- Type: 4096MB DDR3 SDRAM
- Speed: @ 1,333MHz
- Timings: CL7.0 7-7-21
VGA details
- Speed: MHz / MHz (Stock)
Mainboard details
- Cooling: Air (Stock)
Disk details
Power details
Recent Comments
DR650SE commented on his own score:
Alienware M17x R2 Notebook
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text:
Top weight may not be a big enough barrier to stop HARLECH CASTLE and he can be fancied to make a bold attempt to make the long journey up from Whatcome a worthwhile venture; Mandalay King and Bertie Vista are also likely to be on the premises, while Chosen One is open to more improvement and, having won his last two starts in a game manner, he cannot be discounted. The last named is a speedy individual and has valuable experience of racing at this course. The son of Choisir is entered again at Nottingham tomorrow, so his connections are obviously keen on exploiting his talents before the BHA assessor intervenes. Bertie Vista is a more sporting choice, as he doesn't appear to be especially well handicapped just now. Still, he is consistent and has very little to find to make the frame. Mandalay King is also paying the price for his dependability but still needs to keep on improving. However, his latest start suggests he is now at the ceiling of his abilities and he needs a bit of luck on his side this afternoon. In contrast, Harlech Castle, who was started the season on a mark of 93, has been given a real chance from his current mark of 75 and, as a 4lb rise for his Nottingham success looks fair, Paul Cole's charge is taken as the best bet in this company.
Harlech Castle 11-2 (9-0) Towards rear, headway well over 1f out, stayed on to lead towards finish, won at Nottingham 5f 3yo hcp (5) gs beating Nickel Silver (8-9) by 1/2l, 13 ran.
Style Award 25-1 (8-13) Mid-division, outpaced halfway, driven and stayed on final furlong, 5th of 10, 5l behind Willkandoo (8-11) at Catterick 7f 3yo hcp (4) gd in Aug.
Tyfos 25-1 (8-10) Held up rear, well beaten over 1f out, last of 9, 8l behind Green Park (9-5) at Chester 5f hcap (4) gs in Sept.
Bespoke Boy 50-1 (9-4) Tracked leaders, hard ridden over 2f out, soon weakened, well behind final furlong, last of 12, 26l behind Borasco (9-3) at Redcar 7f hcp 0-80 (4) gd in Aug.
Chosen One (IRE) 7-2jt-fav (8-11) Tracked leaders and keen, ridden and outpaced over 1f out, stayed on to lead towards finish, won at Hamilton 6f 3yo hcp (5) sft in Sept beating Baronovici (8-4) by 1/2l, 10 ran.
Splash The Cash 10-3 (8-8) Tracked leaders, ridden over 1f out, soon weakened, 7th of 8, 14l behind Jaconet (8-5) at York 5f 3yo hcp (4) gf in Jul.
Mandalay King (IRE) 5-2fav (8-4) Track leaders, ridden to chase winner final furlong, no impression, 2nd of 10, 3 1/2l behind The Twelve Steps (8-10) at Thirsk 6f 3yo hcp (5) sft in Sept.
Feeling Fresh (IRE) 10-1 (8-7) Slowly into stride, soon outpaced behind, stayed on well final furlong, 7th of 13, 4l behind Harlech Castle (9-0) at Nottingham 5f 3yo hcp (5) gs.
Bertie Vista 16-1 (8-8) With leaders, led entering final furlong, headed towards finish, 3rd of 20, 1 1/2l behind Strawberry Moon (9-2) at Redcar 7f 3yo hcp (5) gd.
Royal Acclamation (IRE) 12-1 (9-3) Held up towards rear, headway over 1f out, kept on well, 5th of 16, 6l behind Music Box Express (8-8) at Warwick 6f hcp 0-65 (6) gd in Sept.
Andrasta 33-1 (8-4) In touch, one pace from over 1f out, 9th of 13, 5l behind Harlech Castle (9-0) at Nottingham 5f 3yo hcp (5) gs.
Rascasse 66-1 (8-4) Slowly into stride, soon outpaced and always behind, 9th of 11, 11l behind Todber (9-5) at Musselburgh 5f 3yo hcp (6) gd in Sept.


text: Hey Guys, I need some help finding something. the reason I need the help is I have no idea what its called. Do you ever recall watching an old film and every now and then you would get what appears to be a blip (or burn hole) in the top right of the picture? Does anyone know what I mean? If so does anyone know what its called? I don't know whats it use is and I can't find the correct words to search for it. If this is really obvious then please feel free to laugh at me but I need help. haha Cheers Liam


text:
Components of the Package:
GO! With Microsoft Office 2010, Vol. 1, and Student Videos
By Shelley Gaskin, Robert Ferrett, Alicia Vargas, Carolyn McLellan
myitlab without Pearson eText -- Access Card -- for GO! Office 2010 Vol. 1
By . . Pearson Education
GO! with Concepts Getting Started
By Shelley Gaskin, Victor Giol
GO! with Microsoft Outlook 2010 Comprehensive
By Shelley Gaskin, Nancy Graviett, Alicia Vargas
GO! with Windows 7 Getting Started with Student CD
By Shelley Gaskin, Robert Ferrett
Add to CartGO! with Windows 7 Getting Started with Student CD


text:
About Our Practice
Learn More
Innate Chiropractic & Wellness Studio was founded in 2004 by Dr. Stefan Cohen and his wife, yoga teacher Debbie Gilman. They envisioned Innate as a hub in the Albany community, providing a clean, modern and safe place for healing and self-empowerment. At Innate Chiropractic, we offer holistic and sports oriented Chiropractic, Therapeutic Massage, Acupuncture, Nutrition, Yoga and Pilates individual and small classes. We also offer periodic workshops on health & wellness, meditation, fitness and self-empowerment. We hope that you will join us in this wellness journey.


text:
"Depression / Suicidal Thoughts - GP referral"
Posted via NHS Choices
I was referred to the clinic to see a psychiatrists over a year ago and have been there again today.
I have nothing but respect for everyone that works there. Reception are friendly and understand, especially when I've been a bit late, doctors are empathetic and ive always felt comfortable. The clinic is clean welcoming and not too busy hectic and stressful. Its helped me.
Do you have a similar story to tell? Tell your story & make a difference ››
Response from Longbridge Health & Community Centre nearly 2 years ago
Thank you for your review,
We really appreciate hearing positive comments regarding our services and it's always nice to get some good feedback. We will pass your comments on to our team at Longbridge who I'm sure will appreciate it as much as we do.


text: I'm selling my EVO because it's a little too big for my hands. It was recently swapped out because my first one was bad, so this new one is only about 2 weeks old. From day one, it has had a Stenheil UC screen protector, phantom skinz back cover and Seido Innocase 2 new rubberized version) applied. It is also rooted WITH 1.4 PRI. Here is what it comes with: -EVO 4G (model 003, nova screen, rooted with PRI 1.4) -Box w all accessories including charger -Seido Innocase 2 (new rubberized version, fits like a glove now) with holster -Stenheil Ultraclear protector -Phantom Skinz= back and kickstand cover applied, An extra front, back and two sets of sides will be included - Amzer argyle skin case in smoke gray This phone is in literal perfect condition. Price is $400 + shipping!


text:
Roadkill Charades
- Artist: David Scott Jack
- Format: CD
- Release Date: 10/4/2005
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David Scott Jack Composer and musician, David Scott Jack dishes up a heroic dose of harmonic layers saturated with a blend of musical styles supported by a solid Rock foundation. With an intention that's strong and direct, Roadkill Charades travels beyond whiskey soaked soundworlds, with the desperation and resolution of acceptance, growth and maturity. David states, 'As I mature, I feel the need to create songs that are increasingly potent, expressing the soul opening above the ordinary states of desperation and beyond everyday life that can seem like the highway to hell.
To play the media you will need to either update your browser to a recent version or update your version of Flash Player.


text: Deep Marine Technology, Inc. announces the signing of a long term lease agreement for the DP II Agnes Candies Dive Support Vessel. The Agnes Candies is 220-ft., U.S. Flagged vessel with: 40T Knuckle Boom Crane Brand New, State-of-the-Art 1000fsw 12 Man Saturation System with Hyperbaric Rescue Chamber Gas Mixing System Diver Reclaim 3 Man Bell Surface Dive Station Accommodations for 42 The Agnes Candies can be adopted for a large spectrum of work ranging from Repair and Installation to Inspection and Plug and Abandonment. Other possible uses for the vessel include platform repairs; riser, anode, and hot tap installations; subsea tree and valve assistance; and platform and pipeline inspection. The Agnes joins the 150-ft. Mother Theresa DSV also on long term lease to DMT. We are currently selling time slots for both vessel spreads during periods that are not committed.


text:
Results 1 to 1 of 1
Thread: Informix DBA/Consultant
04-18-06, 12:32 #1Registered User
- Join Date
- Apr 2006
- Posts
- 1
Informix DBA/Consultant
We currently have a position available on the Database Administration Team. This position offers the role of Database Administrator supporting Informix v5.x, v7.x, v9.x and v10.x on UNIX and Linux environments.
·Creation and setup of Informix Instances and databases.
·Standardization and documentation of Informix database environments.
·Develop and administer processes for performance tuning of databases.
·Develop and administer processes for capacity planning.
·Provide proactive performance monitoring of databases ensuring service levels are met.
·Administrate change control of physical data structure for all environments.
·Develop and administer backup, restore and disaster recovery procedures for databases.
·Create physical data structures from either vendor supplied data base design or custom data base design for all environments.
·Look beyond initial design requirements to create optimal database configuration that meets the business needs.
·Provide 1st-Level support for all database platforms
·Provide 7 x 24 on-call support (primary or backup) on a rotating basis for Informix databases.
The position is on a contract basis, six months with possible extension(s)
David Ayres
Fusion Alliance, Inc.
4555 Lake Forest Drive, Suite 325
Cincinnati, OH 45242-3760
Phone: 513.563.8444 Ext. 5005
Toll Free 866-756-9888
Mobile: 513-256-7535
Fax: 513.563.2270
Visit us at www.fusionalliance.com


text:
After receiving a renewal for seasons six and seven earlier this year, the FX animated spy comedy "Archer" was further bolstered by being selected for syndication by the Comedy Central network. The syndication deal covers all previous seasons plus future seasons of the show which recently completed its fifth season. For the first two years of the agreement, Comedy Central made the deal to exclusively show "Archer" reruns before midnight while, additionally, "Archer" reruns will appear on FX's sister network, FXX, post midnight. "Archer" is currently basic cable's second-highest rated comedy in the 18-49 demographic.
"Archer" previous season reruns are currently scheduled to begin appearing on Comedy Central in May 2015.
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text: Hello I am new to this online community. After going through countless Blackberries and other crappy phones I discovered Android. I first started with a Cliq XT and since at the time it could not be rooted or flashed (at least that's what I thought) I swapped with an already rooted Samsung Behold II. I really enjoy reading the stuff on here and BH_MAN's work. I made my Behold II not be such a laggy piece of crap with his Galaxy firmware... Look forward to seeing me on here a lot mostly testing stuff and giving feedback.


text:
My mother-in-law lived at Agape Villa in April until she passed away on May 9, 2016. She was on hospice care and only lived another 3 weeks after moving there. From the first day until she passed, the owners and the staff at Agape Villa were very loving, compassionate and gave wonderful care to our mom. The home is beautiful, the food home-made and tasty, and the caregivers attentive, kind and loving. I highly recommend Agape Villa to anyone who needs assisted living or hospice care for their loved ones.
Agape Villa Care Home II
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Reviews of Agape Villa Care Home II
September 25, 2016
I am a friend or relative of a current/past resident
November 26, 2014
I am a friend or relative of a resident
Beautiful home designed for the purpose, but most importantly owned and run by interested compassionate people who give individual supportive care tailed to the individual resident's needs and wants. Relatives welcomed and assisted. Critical importance or resident poodle and bird feeders recognized.
Photos of Agape Villa Care Home II
Features of Agape Villa Care Home II
- All Inclusive Rent
- Rent Plus Care Fees
- Fee Structure Extra: Base Plus Level Of Care, All Inclusive
Room and housing options
- Companion Suites: We Offer Companion Suites
- Housing Extra: Private Suites With Bathrooms Attached
Dining options
- Dining Room Shared Meals
- Room Service For Meals
- Resident Transportation
- Party Space
- Tv Room
- Garden And Patio
- Resident Parking
- Pool
- Features Extra: 24 Hour Resident Paging System, Monitored & Secured Entry, Wander Guard System, Medication Management, Pet Therapy, Music Therapy, Furnished Rooms,
Cleaning services
- Laundry For Linens
- Housekeeping
- Laundry For Clothing
Technology and entertainment
- Cable In Rooms
- Internet Enabled Rooms
- Wifi
Health services
- Hospice Care
- Medication Management
- Music
- Games
- Stories
- Religious Services
- Book Clubs
- Fitness Room
- Gardening
- Cooking
- Arts And Crafts
Financial guidance
- Home Sale Assistance
- Va Benefits Consultation
- Financing Advice
Guest services
- Guest Parking
- Guests At Mealtime
- Staff Patient Ratio: 2 3 Staff To 6 Residents
- Minimum Age: 65
- Pets: Small Pets Allowed
- State Licenses: 317005164
About Agape Villa Care Home II
Agape Villa Care Home II is an assisted living facility in Roseville, CA that offers residents independent living options and daily support services. Contact Agape Villa Care Home II for more details on housing, services, and rates.
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Carlos Madrid
Senior Designer
Skidmore, Owings & Merrill LLP
Carlos Madrid III is a Senior Designer with the Los Angeles office of Skidmore, Owings & Merrill. As a design lead, he has more than 15 years of experience in the architecture and interior design industry globally. His broad portfolio includes projects of diverse scale, scope and location such as a new 120,000 square foot office and classroom building for the University of Southern California, Envision Energy headquarters building in China, and a hotel repositioning project in Shanghai. His clients include CBRE Investors, Jones Lang LaSalle, Los Angeles World Airports, Maguire Properties, and Thomas Properties Group. Madrid's current work is a renovation to the Central Terminal Area (CTA) at Los Angeles International Airport (LAX). In addition to the CTA, he is working on an interior renovation of LAX's Terminal 2 atrium, a bridge prototype to replace the seven that connect the terminals to the garages and a multitude of office building repositioning projects for various developers.
Jon Otis, IIDA
Founder and Principal
OlA - Object Agency
Jon Otis is the Founder and Principal of OlA - Object Agency, a multidisciplinary design studio and design strategy agency in New York City. He is also a tenured professor at Pratt Institute, teaching courses in interior design and exhibition design. He earned his bachelor's degree from Moravian College and Master of Science degree in design from the University of Massachusetts. Otis has been awarded Fulbright and Lusk Fellowships to Italy where he spent several years working with design legend Ettore Sottsass. In 2009, he was honored with Design Intelligence's Most Admired Educator award and has been developing an interdisciplinary MFA program in interpretive planning and design at Pratt. Otis is active in organizations such the AAM, IDEC, IIDA, IDSA, AIGA and has lectured at industry conferences Including NeoCon, IIDEXCanada, and at Vitra design workshops in Boisbuchet, France.
Suzanne Tick, Affiliate IIDA
Suzanne Tick Inc.
Suzanne Tick is the founder of Suzanne Tick Inc., specializing in materials brand strategy, product design, development, and direction for commercial interiors. She is currently partnering with Tarkett on brand strategy and product development, is creative director for LUUM, and design consultant for Tandus Centiva. She has maintained a distinguished career as a textile designer and studio principal in New York City. In addition to her work in commercial interiors, Tick maintains a hand weaving practice and creates woven sculptures from repurposed materials. Her work is exhibited worldwide, including MoMA and Art Basel, as well as collected by private and corporate clients. Recently two of her upholstery fabrics, Line Language and Bonded, both for Teknion Textiles were officially acquired for the permanent collection of the Cooper Hewitt, Smithsonian Design Museum. Her recent awards include a 2016 NeoCon Best of Year Gold Award and Interior Design's Hip Award for Tarkett's Collections Infinies. Her debut collection for LUUM, Starting Point, also picked up a 2016 Metropolis Likes at this year's Neocon. In 2013, Tick was honored with the IIDA Titan Award, given in recognition of significant contributions to the interior design profession.


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The more involvement you can get with your online audience the more successful your internet marketing efforts will be. But your audience won't be listening to you if you're not telling them anything that adds value to their lives.
The more your online audience come to know, like and trust you, the more likely they are to buy from you.
Many newcomers to online marketing worry about engaging with their audience because they are not yet a top performer in their market. But it's okay to be a work in progress. People love to learn from someone who is just ahead of them because it makes their journey seem more achievable. This is true no matter what niche you're in. You can share your progress, your problems and your achievements and help others reach their goals, too.
Always Deliver Value
Only publish only original, relevant, high quality content on your website and social media posts. The more value you provide, the closer you'll build the relationship with your online audience. People don't stick around on websites where they're not engaged.
Use More Video
People are naturally drawn to video. One simple way to improve your online audience engagement is to publish videos to your blog or website. If a picture tells a thousand words, a video tells a million.
Uncover Your Avatar
Every piece of content you create should be as though you are communicating to one person. That one person is your avatar. In other words, the "perfect" potential client that you are attempting to reach. What are their desires, emotions, demographics and other physical and mental personality characteristics?
Give Away Free Stuff
You can give away eBooks, videos, reports, checklists, software, coupons or special offers. The important thing about a freebie is that it should be useful, valuable and of the same quality as the products or services that you sell to your audience. If you give away rubbish, your audience will think that your products are rubbish too.
Increase Engagement On Facebook
Facebook groups are an excellent place for audience engagement. When you start a Facebook group, you can enjoy a very easy-going, cooperative community of like minded individuals. People love to be part of a special community.
Unfortunately, a lot of internet marketers build an email list, then rarely reach out to their followers. You have to keep in constant contact with those people that have taken the time to join your list, or you will never "connect" and form a real relationship that helps you meet your business goals.


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Free Preview of Silverlake
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The last time we saw campaign manager Mark Rollins, he was on his knees begging a reporter to not release a secret sex tape of Senator Mike Cauke. We catch up with the newly-unemployed Mark a few months later as he leaves Washington D.C. and heads back to his hometown of Los Angeles and the laid back neighborhood of Silverlake. Stopping for a night in Palm Springs before arriving at his final destination, Mark runs into former colleague Steve Roman who's now with his new boyfriend Vince.
The three men take the opportunity to strip down in the hot desert sun and explore their tanned, muscular bodies. Mark drops down to his knees to suck the big, thick Italian cock on Vinnie. Looking up at the two lovers, sucking one and then the other, Mark feels the uptight beltway sexual repression fall away and he finally allows himself to enjoy man-on-man-on-man sex.
Moving inside to the master bedroom, the three men take turns sucking and fucking each other. The knowing looks between Steve and Vinnie while they spit-roast Mark sets the stage for Steve to climb into the middle and get fucked by Vinnie while Mark face fucks him. The sexual explosion finally happens when Steve blows his load while Vinnie pounds his ass, Mark lets his own load loose in Steve's face and Vinnie finishes up with a gusher of a cumshot on Steve's abs. One final hug goodbye and Mark heads off to Los Angeles and his new life.
Mark Rollins (David Benjamin) has arrived back in his hometown of Los Angeles and his old neighborhood of Silverlake. Famous for its hills, valleys and 52 sets of staircases that connect them. Mark jogs up the famous Micheltorena Stairs, passing a hot, tattooed, red headed Bennett Anthony. The two share a quick moment that turns into a game of cat and mouse as Bennett leads Mark though the winding streets and narrow passageways until they arrive at Bennet's apartment.
"I love gingers" exclaims Mark as he buries his face in Bennet's hairy ass. The tiny apartment is full of sweat, muscle and sexual energy that a quick fuck with a stranger you only just met. Bennett bends Mark over a folding chair and slides his dick into his waiting hole. A rough fuck is just what Mark needs and Bennett is more than willing to give it to him.
Moving over to the army cot that serves as Bennet's bed, Mark slides his hole down on that stiff fire crotch, bouncing up and down, dripping with sweat and showing off the ripped muscles on his legs, chest and back.
Finally rolling Mark over onto his back, Bennett slides his dick deep into Mark's hole and fucks him with that power you get just before you blow your load. David explodes with Bennet's dick deep inside him and then Bennet whips his dick out, climbs up over Mark's body and blows his load right into his open mouth.
During his house hunting, Mark finds a newly-renovated, two-story townhouse in Silverlake. While the view out the window is perfect, the building manager is even hotter to see and before long, Mark and Micah are fucking with abandon in the empty house. Micah's smooth skin next to Mark's hairy, tattooed body sparkle with sweat as they fuck right by the front door. Moving to the other side of the apartment, Mark rides Micah's dick, his muscular chest heaving and puffing to keep up the pace. One final position has Mark on his back, legs in the air as Micah slams this thick dick into his hole. Some cum swapping seals the deal and Mark has a new place to call home.
Mark Rollins (David Benjamin) has finally settled into his new job, his new home and his new life in Silverlake now for the final piece. Meeting the handsome neighbor he's seen around for a few months, he finally gets his chance to get to know him. Mark and Nate (Mitch Vaughn) finish up a glass of wine and conversation when Nate finally goes for it, leans in for a kiss and then men are off. Kissing and exploring each other's bodies lead to Mark down on his knees sucking off Nate followed by Nate shoving his tongue in Mark's ready ass. Mark moans while Nate slams his thick dick up Mark's open hole, then he gets up and sits down to ride it. Moving to the floor, the two men fuck face to face, Mark blowing a huge load all over himself before Mitch blows his own load. Mark's story gets a happy ending but seems the story for his former employer (Senator Mike Cauke) is just beginning.
Product Information
- Length: 2 hrs. 40 mins.
- Rating: XXX
- Released: Feb 17 2017
- Production Year: 2017
- Empire SKU: 1886950
- Studio: TitanMen
- Number of Discs: 1
- UPC Code: 659819108263
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- Age / Gender:
- 34, Male
- Location:
- Over the rainbow
- Joined:
- 2/19/01
- All Stats >
Je suis un artiste, motherfucker
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Level 24 Blank Slate
Silver Whistle
Ranked as Police Officer
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Latest News
Wish I could upload it here, but alas, it's up to Adult Swim.
The biggest game I've ever made! Maybe not the best, but definitely the biggest, most polished, and no doubt longest.
Latest Games
Orange Boxing Rated Stars Box an orange all day long Fighting - Brawler Libyan Hamburger Recipe Rated Stars My (very small) contribution to the Libyan revolution. Simulation - Other Experimental Gameplay... Rated Stars If you thought Super Mario Bros Crossover was cool, wait till you get a load of this! Platformer - Hop and Bop The Maze - The RPG Rated Stars I wanted to try and make an RPG... Adventure - RPG
Latest Movies
Latest Audio Submissions
|It's not about King Bhumibol
|Indie Song
|Det är över nu igen
|Ambient Loop
|Det är över nu
|Ambient Loop
|Magasinet som försvann
|Ambient Loop
Latest Favorite Audio
|Miscellaneous Song
Latest Favorite Movies
Captain Tardigrade Rated 4.5100 Stars Captain Tardigrade defender of the multiverse! Comedy - Original Easy Way Out Rated 4.3900 Stars You gotta reap what you sow, boy. Music Video A Short Flash about Clams Rated 4.2600 Stars Ah, the beauty of nature. Experimental Red Diamond Dragon Club Rated 4.4900 Stars pshhhhhhh Comedy - Original
Latest Favorite Games
Oiligarchy Rated 4.3700 Stars Drill An Oily Empire! Strategy - Other Morningstar Rated 4.4100 Stars Escape from a desolate planet that your spaceship has crashlanded on. Adventure - Point 'n Click Neverending Light Rated 4.4000 Stars A guided tour goes horribly wrong when everyone gets eaten by monsters! Adventure - Other DUCK SIM 2008 Rated 2.7200 Stars Have you ever wondered what your life would be like if you were a duck? Simulation - Other
Recent Game Medals
First of Four 5 Points Defeat Shellbreaker! Medal Stats.
Together At Last 25 Points Here my heart can rest. Medal Stats.
Spread Some Amour 25 Points They were meant to be. Medal Stats.
Grab Bag 5 Points Grab the bag! Medal Stats.
Mee-Yow! 10 Points A WILD CatFight ensues! Medal Stats.
100 MPH Spank! 10 Points Whoops! I hope you like wrinkles! Medal Stats.
I ain't sayin' you a golddigger. 10 Points But you ain't messing with no broke.. nibroke ;) Medal Stats.
Dressing in Drag 10 Points Rambo is quite the prankster! Medal Stats.
Extra! Extra! 10 Points Check out any of the external links Medal Stats.
20_coins 5 Points Collect 20 coins. Medal Stats.
Total Medals Earned: 352 (From 69 different games.)


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So some questions in life that are yet to get answers. and some answers that I keep repeating to myself and others. Who knows might help me if not anything else, to restart my writing! so they will be – "Life: Perspectives" and "Life: Paradox"
sputter sputter.. vroom vroom vroooom!
- Follow Abode of Horus on WordPress.com
My Other Worlds~
Horus Cloud
Blogs I Follow
- একটি শিমুল আর এক টুকরো আকাশ
- RainbowInMyVeins
- Or Margaritas... whatever works!
- Books by Sharmishtha Basu
- laksie speaks
- tunaswish
- A Lone Stranger
- ChakraVIEW
- AditeBanerjie
- Bryan Hemming
- Rochelle Wisoff-Fields-Addicted to Purple
- Sakshi Vashist
- The Green-Walled Tower
- Chiku's Transformation
- Miss Lou Acquiring Lore
- Indie Adda
- the thinking closet
- River Song
- Colours and Words Waltz
Top Rated


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Lafuma Garden Furniture
Lafuma have used their knowledge of how to combine strong fabrics with lightweight frames in the development of their range of outdoor tubular furniture. Combine this with the French flair for design and you have a range of furniture that surpasses all others.
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MOVIE SYNOPSIS [ +16 years-old ] Under the direction of Jonathan Meyers, Justin Baldoni leads the cast of this feature film originally of USA, with original script in English (subtitled), whose premiere was scheduled for 2014. You can watch A Fine Step online on TV cable or theaters with original audio in English at different dates. This film premiered in theaters in 2014.
Rating: 5 by 166 users./
Runtime: 90 minutes
Justin Baldoni, Luke Perry, Armand Assante, Leonor Varela, Cameron Daddo, Anna Claire Sneed, Cylk Cozart, Ashley Ann Vickers, Oliver Macready, Amy Lavere, Donald Meyers, T.J. Cates, Mannie De Castro, Carol Lynn Hovland, Nora Childers and Stacey A. Robinson.
90-minute film (full movie) directed by Jonathan Meyers.
The original audio of A Fine Step has dialogues in Dolby Digital, it was produced in USA.
It premiered in cinemas or television in 2014.
Screenplay written by Keith Suggs, Dennis Sonnenschein and Gregory Gieras.
Gavin Kelly.
Nicholas Celozzi, James R. Rosenthal, Jon Yarbrough, Cassidy Lunnen, Ari Palitz, Justin Gullett, David Dunavant, Doug Ames, Bret Saxon, Ron Coleman, Dennis Sonnenschein and Mike Mazzella.
This film was produced and / or financed by Insomnia Media Group.
Umbrella Entertainment, Vertical Entertainment and Capelight Pictures.
Without commercial breaks, the full movie A Fine Step has a duration of 90 minutes; the official trailer can be watched in streaming on the Internet. You can watch this full movie free in EnglishDolby Digital in movie TV channels, renting the DVD or with VoD services (Video On Demand player, Hulu) and PPV (Pay Per View, Netflix).
See the page of this full movie, A Fine Step in FULLTV Movies.


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More wines available from Marques De Grinon
Marques De Grinon Dominio De Valdepusa Syrah 2006 Customer Reviews
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Additional Information on Marques De Grinon Dominio De Valdepusa Syrah 2006
Winery Marques De Grinon
Varietal: SyrahWhilst there remains plenty of debate over which is the 'correct' name for the Shiraz/Syrah grape varietal, nobody is in any doubt about the influence and popularity this grape has had over recent decades. For centuries, this varietal has been used in single variety and blended wines in the regions of France it is most closely associated with, yet the 20th century saw it become one of the definitive grape varietals of New World red wines, where its big, robust character and spicy, berry-rich flavors proved to be a hit with international audiences. Today, Shiraz/Syrah is said to be the seventh most widely planted grape varietal in the world, and is used for a remarkably wide variety of quality red wines – including still, sparkling and fortified varieties.
Country: Spain
Ever since the Phoenicians and Romans brought their knowledge of vine cultivation to Spanish soils, the country's culture has grown alongside wine production, with wine being a vital part of Spanish identity and Spanish traditions. Each region of Spain has a wine quite distinct from the others, and it is produced by smallholders and families as much as it is by large companies and established wineries. From the relatively mild and lush regions of La Rioja to the arid plateaus that surround Madrid, grapes are grown in abundance for the now booming Spanish wine industry, and new laws and regulations have recently been put in place to keep the country's standards high. By combining traditional practices with modern technology, Spanish wineries are continuing to produce distinctive wines of great character, flavor and aroma, with the focus shifting in recent decades to quality over quantity.


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Also included are some "In Flight" service photographs taken on board both the DC-8 and Boeing 707, as well as many detailed destination photographs, images and descriptive text. Countries include Brazil, Chile, Argentina, Panama, Colubia, Ecuador, Boliva, Paraguay & Uruguay.
This highly collectible piece of airline memorabilia is in Excellent condition and was originally printed in the U.S.A 9/1962. Form DR-F-137-78. Perfec item or gift for that airline or aviation enthusiast! Please Click on Image For A Closer Look!


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|28 Mar 2014
Microsoft Office 2013, Error 1317 Setup cannot create the folder
I'm trying to install Microsoft Office 2013 Professional on my laptop from a USB with the OFFICIAL ISO on it, not a torrent. I am getting an error which reads
"Error 1318. Setup cannot create the folder
C:\ProgramData\Microsft\OFFICE\UICaptions. Verify that the path exists in your system and that you have sufficient permissions to update it."
I am the only account on this laptop, being an administrator, I have tried running this as an admin, changing the permissions of the OFFICE file in ProgramData to "Full control" and it replied with "Access is denied." while trying to apply security information.
When I try double-clicking the OFFICE file in the hidden ProgramData folder, it says that the file or directory is corrupted and unreadable.
Any ideas on how I can get around this issue, any help would be much appreciated, thank you for reading.
|My System Specs
|28 Mar 2014
Welcome to the forum. Open a cmd prompt then type
chkdsk c: /r
say yes to check on reboot the drive may be corrupt thats giving the problems
|My System Specs
|28 Mar 2014
I tried defragmenting the disk but C: doesn't even show up in the list, the only disk that shows up is "System Reserved".
I also tried chkdsk c: /f and it said the same thing as the above command.
|My System Specs
|28 Mar 2014
run the cmd again say yes to test on startup then wait 10 mins then reboot see if it does it then
|My System Specs
|28 Mar 2014
Now it said it found errors, but it can't continue in read only mode.
|My System Specs
|29 Mar 2014
Have you got an install cd boot from that choose repair and then cmd prompt then do the
chkdsk c: /r
so its not in use there seem to be errors on the disk giving the problems
|My System Specs
|31 Mar 2014
This error occurs when you have set incorrect permission on your OS. For more information, please check this link: How do I restore security settings to a known working state?
|My System Specs
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In the pursuit of the Group's strategy and objectives, our CORE values determine our every action:
• Honesty, integrity and transparency drive our every operation.
• Responsibility and ownership for our actions.
• All stakeholders are seen as equal and valued assets.
• Our people drive our performance and results.
• Our vision for our stakeholders is to deliver value long-term but with stability
being a core pillar.
• Responsible corporate citizenship in respect of our social and
environmental challenges.
Putprop is a property investment company listed on the main board of the JSE Limited under the real estate sector.
The Company listed on 4 July 1988. (JSE code: PPR) (Registration number: 1988/001085/06) The Company invests in industrial, commercial and retail properties, deriving its income from contracted rentals.
Putprop's primary objective is to build a quality portfolio with strong contractual cash flows resulting in long-term sustainability and capital appreciation.
Growth will come from strategic investments, focused on industrial, retail and commercial opportunities where yields are enhancing in the medium and long-term.
• Optimise our net income and grow distributions above sector average.
• Reduce our present over-dependence on one single tenant for the major
contractual rental inflow.
• Optimise the asset quality of our portfolio by disposing of non performing and
low grade individual properties.
• Reduce our overweight in the industrial sector by investing in quality, high
yield retail and commercial assets - a balanced sectoral portfolio.
• Gearing to be limited to 35% of our total assets.
• Achieve a balanced geographical exposure in all of our target provinces.
• Achieve lease expiry profiles that the bulk of the contractual rental income is
older than three years.
• Reduction in income from one single tenant from 82% to 55% total
contractual rentals.
• Sale of Selby Property to allow repositioning in our portfolio and
allow a special distribution to shareholders.
• Gearing during the year increased to 18% from 7% in 2015, but was
well below our mandated level of 35% of total assets.
• Increased holdings in subsidiary and associate companies with long
term contractual rentals.
|Target Performance-2015
|Broaden our geographic footprint Into all of the provinces in South Africa
|The Group wishes to position itself for long term expansion of its portfolio into all provinces
|Acquisition of first property in North West
|Optimise net income and growth in distributions.
|The Group will pursue a more aggressive policy of purchasing high-quality assets, while maintaining focus on refurbishments and redevelopments.
|Several assets have been identified for possible acquisition
|Reduce vacancies and manage the lease expiry profile of the portfolio.
|Continue to reduce vacancy Levels to less than property sector average and to increase average lease length of portfolio.
|Vacancy level of 6% or less for all sectors
|Stagger lease expirys on all properties
|Ensure that not more than 30% of all leases expire in any one year.
|Expiry profile set at 15%
|Achieve a balanced exposure to the office, retail and industrial property sectors.
|Weighting on all sectors to be revisited on an active basis
|Commercial sector to be addressed
© 2014 Putprop Limited


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Severance: Blade of Darkness Revisited
View Single Post
November 20th, 2006, 18:02
i finished the game with the knight and barbarian over the years but never ended up finishing it as the dwarf or amazon. i like the fact that they all start on their own unique levels a huge bonus for replayability since the intro/begining of most games is often the most boring gameplay wise.
i can't believe i spent actual money, and the time to finish it, on rune way back when. its in the top 5 of worse games i have ever played. there really needs to be a good 'viking' game - especially since i'm half scandanavian.
liberty or license
Join Date: Oct 2006
Location: California
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I'm not normally one for making outfit collages for posts, but after seeing this gorgeous black and white dress on Phase Eight's website when I was invited to enter their Blogger Wedding Guest Outfit Competition, I had an Audrey moment and couldn't resist...!
Admittedly the dress is a similar style to the one I wore on Christmas Day, but that's probably why I rather liked it. I also chose it because black and white is the trend for 2013, but decided to soften it with the shell necklace and clutch - I just love those muted colours and textures (plus I thought they made a change from the usual pearls and a satin clutch so often paired with this kind of dress). I'd wear the shrug in the evening for a little warmth - usually needed for a British wedding - and it would also look great with the right kind of maxi dress, so it'd be quite a versatile item.
The prize? A £250 Phase Eight gift card. More than enough to buy a complete wedding outfit, which would be rather wonderful ;)
Come back later today for news of a great new feature on the blog, plus I'll have a new outfit post tomorrow. Happy Friday everyone!
Shop the look:
Darcy Grosgrain Bow Dress, Madeline Shrug, Sophie Bow Slingback Shoe, Shell Disk Necklace, Tia Shell Clutch Bag (all Phase Eight)