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Results 1 to 5 of 5
January 13th, 2002, 12:20 PM #1
My stats at CJ tell me I had 2500 impressions
yesterday with 4 hits. My counter tell me I had 9 visitors. Which is correct? Alsu has anyone heard from Big Chuck from the coupon guy?
January 13th, 2002, 02:17 PM #2
- Join Date
- January 18th, 2005
- Posts
- 9
I'm pretty sure the impressions come from a random number generator. Hits seem to track OK though.
January 13th, 2002, 02:28 PM #3
- Join Date
- January 18th, 2005
- Posts
- 2,279
Counters and page-load tracking systems are notoriously error-prone (for example, the one on ABW hangs on EVERY page load for me, I just hit the stop button and it RARELY loads), so I wouldn't put too much stock in that.
And 9 visitors could result in 2500 impressions -- dependent on how many ads you have per page and how many pages those visitors visited (it's a bit far-fetched, but it could happen).
Personally, I'd trust the CJ stats over a counter every day of the week.
January 13th, 2002, 02:34 PM #4
- Join Date
- January 18th, 2005
- Posts
- 270

quote:
Which is correct?

All of them. [img]/infopop/emoticons/icon_smile.gif[/img]
To be more precise, the numbers are rolled up with the information that the software has available to it, so all of them would be correct.
CJ hits seem to be recorded fairly accurately, although the impressions can be so far off it isn't funny. That could be caused by quick clicking or Net latency, so we use these numbers as a guideline at best.
For our own purposes, we have software that uses our server log files, and we rely more on that than anyone else's numbers.
The only number that is Absolutely, Positively, Guaranteed correct is the number on the check when we cash it.
January 13th, 2002, 03:59 PM #5
"The only number that is Absolutely, Positively, Guaranteed correct is the number on the check when we cash it.~CodeJockey"
That's the only number that's important anyway!
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17 Jan, 17
Fun Stuff
Coffee breaks are sooo 2016...
A masturbation break is the best boost for a productive day according doctor in psychology Cliff Arnall.
In the British newspaper Metro the psychologist says that a masturbation session leads to less aggression, higher productivity and a good mood. A masturbation break is the perfect cure for boredom at work, and helps you keep your wits about you. So go ahead and procrasturbate for the greater good.
But there are also a few drawbacks, the psychologist notes.
For example masturbating at work can lead to quite uncomfortable situations at the office (no shit, Sherlock). Or maybe you'll do not even climax in time for the end of your lunch break, leaving you walking around frustrated the rest of the day.
Last but not least: he encourages employees not to fantasize about a colleague, because it can quickly lead to undesirable behavior. What if that hunk from the third floor were to bump into you when five minutes earlier you fantasized about him taking you firmly from behind against the copier? Awkward…
Whether you want to integrate this kind of breaks in your day is up to you. Masturbation is not illegal, but in many situations we still find it inappropriate to finger paint / paint the ceiling (delete as appropriate) for fifteen minutes so take this career advice with a pinch of salt, or a Kleenex.
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subset: commoncrawl


text:
off to amman, jordan, drive to dead sea and Perta
Sharm El Sheikh Travel Blog› entry 5 of 12 › view all entries
well proceed to the airport and that was fast about 10 minutes to get on plane to jordan the flight on jordain air was $236 and when you arrive to you need another visa that was $20 and we just gave them $100 US and got the change to tie us over. there i had a rental car set up which you have to look for a person holding your name as i wasn't aware and looked for a rental car booth, but none to be found!
we arrived in amman around 3 pm found the rental car that was booked through expedia for around $250 for 3 days, we got a map with the car and headed to the dead sea for a swim at sunset! the road signs where pretty easy to follow so but just in case: take 15 to the 30 west to the 65 south and just follow the signs to amman beach it was only $10 jordan dollars and took about 45 min from the airport.
from there i drove to Petra which was a pain in the ass! no signs and very little markers, we ran into about 8-10 military check points/peed traps where they were carrying fully automatic weapons. ask where we were from and passports everytime, as soon as i pulled USA passport they were GREAT! very helpful and friendly so to get to petra from the dea sea a littl eover 3 hours and i was driving fairly fast: stay on 65 south to 60 east that would be right to Tafla heading left and SE to Petra. you will head over a steep mountian pass with absolutely NO signs make a right on 35 south to Shobak and follow to Petra as you will see signs now.
we stayed at the first hotel in Petra the Movenpic and for 3 in a room was on for $75.


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On this festive episode of Binwalla Radio Gerald, James and Phil are joined by Meghan to talk shop and wish everyone a Merry Christmas you filthy animal. Topics ...On December 22, 2016 / By Gerald Keil
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|25 Mar 2011
Keyboard layout HELP !!! Please
I have a new "Microsoft" keyboard The Shift + 2 key should be @ key but is the " key. plus the hash key is nowhere to be found and the shift + 3 key that should be the hash is the £ key ...... Help please????
|My System Specs
|25 Mar 2011
You have keyboard language set to English (United Kingdom), which gives " with SHIFT+2 and £ with SHIFT+3. If you need an English keyboard layout that gives @ with SHIFT+2 and # with SHIFT+3, you need to change the layout to English (United States).
Here you can see the difference. First UK English:
And US English:
(Click images to enlarge.)
|My System Specs
|25 Mar 2011
You are welcome.
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ShivanDragon (96) Leeuwarden, Netherlands | September 8, 2017
Just a tourist bar, nice to visit with a soccer team and just drink a lot. For ratebeer this is a no go.
sic1314 (476) Leiden, Netherlands | April 2, 2015
Not sure what this is doing on ratebeer, just another tourist bar, nothing very exciting to drink.
JulienHuxley (416) Sherbrooke, Quebec | March 8, 2014
Been here a couple of times with friends, never noticed it was a ratebeer place. Kind of gives you an idea. There's lots of seating and a variety of macros on draft. Pretty people if you ever get tired of looking at the not always visually pleasing hardcore beer drinkers. Do no visit for beer.
Borresteijn (290) Zaandam, Netherlands | December 4, 2013
Large Irish pub on the most touristy square of Amsterdam, with a few bottles besides their tap line-up, which consists of Bavaria, Guinness, Kilkenny, Murphy's, Magners. Pub grub available. Sat here many times enjoying a Guinness in the sun, outside on the patio, or while watching football, but this really isn't worth a Ratebeer addition imho.
kermis (551) The Hague / Amsterdam , Netherlands | June 22, 2013
Nice enough pub, but not really one that should be on Ratebeer. Would certainly go there again but not for craft beer..
altonbrownd (341) Chevy Chase, Maryland | May 4, 2012
Okay been here tons of time with Pieter and Boris. Not much happening here save a few UK macros. Questionable addition.
MMR (16) , Netherlands | March 13, 2012
Mwoi, mwoi, a pub with a very nice ambiance but that's about it. It's overall pretty expensive.
tkrjukoff (191) , Sweden | January 23, 2012
Typical Irish style pub serving the typical pub menus and beers. Nothing extra ordinary, nice friendly staff and not too noisy interior. Food was good.


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Phospholemman (PLM) is a major target for phosphorylation mediated by both PKA (at Ser68) and PKC (at both Ser63 and Ser68) in the heart. In intact cardiac myocytes, PLM associates with and inhibits Na+-K+-ATPase (NKA), mainly by reducing its affinity for internal Na+. The inhibition is relieved upon PLM phosphorylation by PKA or PKC. The aim here was to distinguish the role of the Ser63 and Ser68 PLM phosphorylation sites in mediating kinase-induced modulation of NKA function. We expressed wild-type (WT) PLM and S63A, S68A, and AA (Ser63 and Ser68 to alanine double mutant) PLM mutants in HeLa cells that stably express rat NKA-α1 and we measured the effect of PKA and PKC activation on NKA-mediated intracellular Na+ concentration decline. PLM expression (WT or mutant) significantly decreased the apparent NKA affinity for internal Na+ and had no significant effect on the maximum pump rate (Vmax). PKA activation with forskolin (20 μM) restored NKA Na+ affinity in cells expressing WT but not AA PLM and did not affect Vmax in either case. Similarly, PKC activation with 300 nM phorbol 12,13-dibutyrate increased NKA Na+ affinity in cells expressing WT, S63A, and S68A PLM and had no effect in cells expressing AA PLM. Neither forskolin nor phorbol 12,13-dibutyrate affected NKA function in the absence of PLM. We conclude that PLM phosphorylation at either Ser63 or Ser68 is both necessary and sufficient for completely relieving the PLM-induced NKA inhibition.
- apparent Na affinity
phospholemman (plm) was first reported as an important phosphorylation substrate for both PKA and PKC (13, 17, 18) in the heart; however, its physiological role was poorly understood. More recent studies (4, 5, 21) indicate that PLM belongs to a family of proteins (FXYD gene family) that bind specifically to and regulate the Na+-K+-ATPase (NKA) in various tissues. PLM is the only FXYD protein highly expressed in the heart and is unique among the FXYD proteins in that it has multiple phosphorylation sites in the cytoplasmic domain.
PLM associates specifically and stably with rat NKA α1-, α2-, and α3-isoforms and reduces their apparent affinity for intracellular Na+ and extracellular K+ when coexpressed in oocytes (4). We (6, 11) have previously shown that PLM reduces the NKA activity, mainly by reducing the apparent pump affinity for internal Na+, in intact cardiac myocytes. PLM phosphorylation relieves this inhibition and thus mediates the PKA/PKC-dependent stimulation of NKA (2, 6, 11). Biochemical studies (10) indicate that PKA phosphorylates PLM mostly at the Ser68 site (although some phosphorylation also occurs at the Ser63 site) and PKC phosphorylates both Ser63 and Ser68 sites. Removal of these phosphorylation sites in the shark PLM-like protein restores the apparent Na+ affinity of the NKA (14, 15). NKA is strongly stimulated in sarcolemmal membranes isolated from ischemic rat hearts compared with the controls, and this is accompanied by activation of PKA and PKC and subsequent phosphorylation of PLM (but not of the NKA α-subunit; Ref. 9). PKA activation by forskolin resulted in PLM phosphorylation at Ser68 and significantly increased the Na+ pump current in isolated guinea-pig cardiac myocytes (20).
PKC activation also increases the maximum Na+ extrusion rate of the NKA α2-isoform in mouse ventricular myocytes (6, 11). Furthermore, the PKA- and PKC-dependent effects on NKA and the phosphorylation state of Ser63 and Ser68 are additive (11), suggesting that the PKA/PKC-dependent pathways are independent in terms of NKA regulation. Thus the aim of this study was to investigate the role of PLM phosphorylation sites (Ser63 and Ser 68) in modulating NKA function. We measured the effect of PKA/PKC activation on the NKA-mediated intracellular Na+ concentration ([Na+]i) decline in HeLa cells overexpressing rat NKA-α1 and determined how expression of PLM [wild type (WT) and its mutants] affect NKA regulation by PKA and PKC.
Construction of viral vectors.
For this study, we used WT canine PLM and the following PLM mutants: Ser63 to Ala (S63A), Ser68 to Ala (S68A), and Ser63/Ser68 to Ala double mutant (AA PLM). The Ser to Ala mutation rendered the respective site unphosphorylatable. The WT and mutant PLM was obtained by cleaving GFP from the PLM-GFP plasmid vector using standard molecular biology methods. They were then subcloned into the pShuttle CMV vector. Adenoviruses were generated with AdEasy Vector system according to the manufacturer's instructions (Stratagene). After amplification, the virus was purified on a CsCl gradient and stored at −80°C.
HeLa cell culture and expression of PLM mutants.
HeLa cells stably expressing the ouabain-resistant rat NKA-α1 (a generous gift from Dr. Joshua Berlin, University of Medicine and Dentistry of New Jersey–New Jersey Medical School; Ref. 18) were maintained in DMEM with 5% FBS, penicillin/streptomycin, and 1 μM ouabain. The medium was replaced every 3 days, and the cells were split via mild trypsinization when confluent. Twenty-four hours before experiments, cells were plated on a 25 × 25 coverslip with a total of 5 ml medium in a culture dish (2% FBS). PLM WT and phosphorylation-site mutants were expressed in these HeLa cells by exposure to the appropriate adenovirus at a multiplicity of infection of 10–50.
Confocal microscopy.
Perfusion chambers containing the cultured cells on the coverslips were mounted on the stage of an inverted microscope. Confocal images were measured with a ×40 oil immersion objective lens. For GFP measurements, excitation was at 488 nm (< 5%) and emission was recorded at 520 nm.
Western blot.
HeLa cells were lysed in ice-cold buffer containing 1% NP-40 and the following (in mmol/l): 150 NaCl, 10 Tris (pH 7.4), 2 EGTA, 50 NaF, 0.2 NaVO3, and protease inhibitors (Calbiochem). Lysates were size fractionated on 15% SDS-PAGE. Proteins were transferred to 0.20 μm nitrocellulose membranes and blocked in 5% nonfat dry milk in TBS-Tween for 2 h at room temperature. The blots were then incubated overnight at 4°C with custom-made primary antibodies (1:5,000 dilution) that detect total PLM (C2 antibody), PLM phosphorylated at Ser 68 (CP68), or PLM phosphorylated at Ser 63 (CP63; a kind gift from Dr. Randall Moorman, University of Virginia; Ref. 20).
PLM dephosphorylation was performed as previously described (3): 100 μg of cell lysate were dephosphorylated with 0.3 U PP2A and 0.3U PP1 (from Calbiochem) for 20 min at 37°C in reaction buffer containing 50 mM Tris·HCl, 1 mM dithiotreitol, and 1 mM MgCl2 (pH 7.5). The reaction was terminated by the addition of 1 μM microcystin-LR (a control reaction was also included that was preincubated with microcystin-LR for 10 min).
Intracellular [Na+]i measurements in HeLa cells.
Cells were incubated with 10 μM sodium-binding benzofuran isophthalate (SBFI)-AM in the presence of Pluronic F-127 (0.05% wt/vol) for 90 min at room temperature. After the external dye was washed out, SBFI-AM was allowed to further deesterify for 20 min in normal Tyrode solution. Dual excitation measurements (at 340 and 380 nm; F340 and F380) were performed on selected area for a group of ∼20 cells (7). The F340-to-F380 ratio was calculated after background subtraction and converted to [Na+]i by calibration at the end of each experiment (using divalent-free solutions with 0, 10, or 20 mM extracellular [Na+]) in the presence of 10 μM gramicidin and 100 μM strophanthidin (7). All measurements were at room temperature.
Na+ efflux through the NKA.
NKA-mediated Na+ efflux was determined as the rate of pump-mediated [Na+]i decline (7). Myocytes were Na+ loaded by inhibiting the NKA in a K+-free solution containing the following (in mM): 145 NaCl, 2 EGTA, 10 HEPES, and 10 glucose (pH 7.4). [Na+]i decline was measured upon pump reactivation in a solution containing the following (in mM): 130 TEA-Cl, 15 KCl, 1 MgCl2, 2 EGTA, 10 HEPES, and 10 glucose (pH 7.4). One micromolar of ouabain was used in most experiments to inhibit the endogenous human NKA. Since cell volume does not change with this protocol (8), [Na+]i decline reflects the Na+ efflux. The rate of [Na+]i decline (−d[Na+]i/dt) was plotted vs. [Na]i and fitted with the following: Jpump = Vmax/{1 + (K0.5/[ Na+]i){↑nH}}, where Vmax is the maximum Na+ extrusion rate of the pump, K0.5 is the [Na+]i for the half-maximal activation of the pump, and nH is the Hill coefficient. Forskolin (20 μM) and phorbol 12,13-dibutyrate (PDBu; 300 nM) were used to activate PKA and PKC, respectively. They were applied in the K+-free solution, 10–15 min before reactivating the pump. As a control, the −d[Na+]i/dt vs. [Na+]i curve is superimposable when two consecutive control runs are done in HeLa cells (similar to the case in myocytes, data not shown).
Statistical analysis.
Data are expressed as means ± SE. Statistical discriminations were performed with Student's t-test (paired when appropriate) with P < 0.05 considered significant.
Measurement of NKA-mediated Na+ efflux in HeLa cells.
HeLa cells were loaded with SBFI and fluorescence was measured as described above. Fluorescence signals from a selected area of ∼20 cells were recorded, and [Na+]i was calculated. Figure 1A shows a representative experiment where two [Na+]i loading/decline cycles were monitored under identical conditions to verify that consecutive control runs result in identical results. In all experiments, 1 μM ouabain was used to block endogenous human NKA. A three-step calibration of the F340-to-F380 ratio was done at the end of the experiment. Similar to what we found in myocytes, consecutive control runs produce similar results (mean data not shown).
In parallel experiments, we measured the rate of Na+ pump-independent Na+ efflux (leak) as the rate of [Na+]i decline in the presence of 10 mM ouabain, which blocks both the exogenous and endogenous NKA. The leak Vmax averages 2.0 ± 0.3 mM/min and accounts for <25% of total Na+ efflux (Fig. 1B). Furthermore, the leak component was not affected by application of forskolin or PDBu in HeLa cells (not shown). The leak component was subtracted from total Na+ efflux to calculate the rate of NKA-mediated Na+ efflux (Fig. 1B).
Effect of PLM expression on [Na+]i homeostasis in HeLa cells.
The WT PLM and mutated PLM used in this study do not contain any fluorescent marker to avoid potential contamination of the SBFI fluorescence signal. In parallel control experiments, the adenoviral transduction efficiency of PLM-GFP is >90% as indicated in Fig. 2A. Western blot experiments showed a comparable level of heterologous PLM expression, whether PLM was expressed alone or in a vector that also contained GFP (Fig. 2B). The noninfected (nonfluorescent) cells are displayed in a different layer and out of focus and are probably dead (Fig. 2A). Thus, during SBFI measurements, we selected areas that were devoid of out of focus and dead cells.
[ Na+]i and NKA-mediated Na+ efflux were measured 24 h after adenoviral infection of WT or mutant PLM. [Na+]i was 5.2 ± 0.5 mM (n = 12) in noninfected cells and significantly higher in HeLa cells expressing either WT or AA PLM (8.3 ± 1.0, n = 9, and 8.4 ± 0.7 mM, n = 10, respectively; Fig. 2C). The higher [Na+]i in the presence of PLM is consistent with a decrease in Na+ efflux via NKA upon PLM association, as shown in myocyte studies (6). Indeed, the total Na+ efflux curve is right shifted upon WT PLM expression (K0.5: 10.7 ± 0.7 vs. 16.7 ± 0.8 mM), without any significant change in the Vmax (7.9 ± 0.7 vs. 8.2 ± 0.6 mM). Thus acute PLM expression decreases NKA activity and elevates [Na+]i in HeLa cells. Moreover, the total efflux rate in HeLa cells without PLM at their [Na+]i of 5.2 mM is similar to that in the presence of WT PLM at 8.3 mM [Na+]i, the value measured under these conditions (1.4 vs. 1.6 mM/min; Fig. 2D). Because steady-state Na+ efflux is equal to Na+ influx, this indicates that PLM expression does not alter Na+ influx rate.
Effect of PKA activation on the NKA-mediated Na+ efflux in HeLa cells; role of PLM phosphorylation sites.
PKA was activated by 20 μM forskolin, and we determined the effect on NKA function by measuring the [Na+]i dependence of NKA-mediated Na+ efflux (Fig. 3 and Table 1). In the absence of PLM, forskolin did not significantly affect either Vmax (5.8 ± 0.7 in control vs. 4.8 ± 0.7 mM/min with forskolin; n = 12), the apparent affinity of the pump for internal Na+ (K0.5 = 11.7 ± 0.9 in control and 11.2 ± 1.4 mM with forskolin) or nH (2.4 ± 0.1 vs. 2.6 ± 0.1). Figure 3A shows the Na+-activation curve normalized to Vmax to emphasize the lack of effect on K0.5. Heterologous expression of WT PLM significantly inhibited NKA by decreasing the apparent Na+ affinity (K0.5 increased from 11.7 ± 0.9 in cells without PLM to 18.5 ± 0.7 mM with WT PLM; n = 11; Fig. 3B). Forskolin largely relieved NKA inhibition (K0.5 significantly decreased to 13.8 ± 1.2 mM; n = 11). The NKA Vmax was similar in HeLa cells with and without PLM (5.6 ± 0.6 vs. 5.8 ± 0.7 mM/min) and was not affected by PKA activation (5.7 ± 0.8 mM/min).
Expression of nonphosphorylatable AA PLM mutant (Ser68 and Ser63 to alanine double mutation) also decreased the apparent Na+ affinity of NKA (vs. NKA only) similar to WT PLM (K0.5 = 16.3 ± 0.6 mM; n = 10; Fig. 3C). However, forskolin did not relieve NKA inhibition in HeLa cells expressing AA PLM (K0.5 = 16.0 ± 0.8 mM). In addition, PKA activation did not change the Vmax or nH of NKA after AA PLM overexpression in HeLa cells (Vmax: 6.9 ± 0.4 in control conditions vs. 6.1 ± 0.5 mM/min with forskolin; nH: 2.8 ± 0.2 vs. 2.6 ± 0.1).
Overall, the data in HeLa cells are consistent with those in cardiac myocytes (2, 6), indicating that PLM inhibits NKA activity by decreasing its [Na+]i affinity and that this inhibitory effect is relieved by PKA phosphorylation of PLM phosphorylation sites. The nonphosphorylatable PLM works like a tonic inhibitor of NKA that cannot be relieved.
Effect of PKC activation on the NKA-mediated Na+ efflux in HeLa cells; role of PLM phosphorylation sites.
We used the same method to determine the effect of PKC activation on NKA function in HeLa cells and the role of the different PKC phosphorylation sites on PLM in mediating this effect (Fig. 4). PKC was activated with 300 nM PDBu. In the absence of PLM, PDBu failed to induce any changes in K0.5, Vmax, or nH (Fig. 4A and Table 1). This implies that PKC does not have a direct effect on NKA transport function under our experimental conditions here. PDBu increased the NKA Na+ affinity in cells expressing WT PLM (K0.5 decreased from 16.3 ± 1.4 mM in control condition to 13.4 ± 1.1 mM with PDBu; n = 9; Fig. 4B) but not in cells expressing AA PLM (K0.5 = 17.6 ± 1.3 vs. 17.7 ± 1.6 mM; n = 7; Fig. 4C). PDBu had no effect on Vmax and nH. Thus PLM phosphorylation is required for the PKC effects on NKA activity.
WT PLM expressed in HeLa cells is readily phosphorylated by PKC at both Ser63 and Ser68 (similar to the situation in cardiac myocytes), as demonstrated using phosphorylation-dependent antibodies (Fig. 5A). There was also a variable degree of baseline phosphorylation at both S63 and S68 (see untreated column in Fig. 5B). We investigated the separate effect of phosphorylation at each site on NKA function by mutating the other site to alanine. PDBu still induced phosphorylation of the S63A PLM mutant at Ser68 and of the S68A mutant at Ser63, as indicated by a 2- to 2.5-fold increase in the signal of the respective phospho-specific antibody (Fig. 5C; note that both alanine mutants display relatively high baseline signals, but these are independent of phosphorylation at that site). We expressed the Ser63A (Fig. 5D) or Ser68A (Fig. 5E) PLM mutants in HeLa cells and measured the effect of PDBu on NKA-mediated Na+ efflux. Expression of either PLM decreased the apparent Na+ affinity of NKA, to a similar extent as seen with WT PLM. PKC activation by PDBu significantly increased the apparent Na+ affinity of NKA in both cases (K0.5 decreases to 14.0 ± 1.7 mM for Ser63A, n = 9, and 13.9 ± 1.3 mM for Ser68A, n = 7). Thus PLM phosphorylation at either Ser68 or Ser63 can relieve the NKA inhibition by PLM to a similar extent and the effect does not seem additive.
The present study shows that heterologous PLM decreases internal Na+ affinity of rat NKA-α1 stably expressed in HeLa cells. NKA inhibition results in a higher [Na+]i in the presence of PLM. PLM phosphorylation by PKA and PKC restores the NKA Na+ affinity and thus relieves the pump inhibition. PKA and PKC activation does not affect NKA function in HeLa cells without PLM or in cells expressing mutant PLM that has both Ser63 and Ser68 sites unphosphorylatable (by Ser to Ala mutations), indicating that these are the only major sites that mediate the PKA- and PKC-dependent effects on NKA. Phosphorylation of either Ser63 or Ser68 by PDBu is sufficient to relieve the PLM-dependent NKA inhibition.
PLM is unique within the FXYD family in that it has multiple phosphorylation sites in the cytoplasmic tail. We have previously shown that PLM phosphorylation mediates the PKA and PKC-dependent regulation of NKA in cardiac myocytes. However, the role of Ser63 and Ser68 phosphorylation sites in mediating these kinase-dependent effects (K0.5 vs. Vmax) is not fully understood. Phosphorylation of PLM at Ser68 mediates the PKA-dependent increase in the Na+ affinity of both NKA α1- and α2-isoforms in mouse ventricular myocytes (2) and oocytes (1). PKC activation also increased PLM-dependent Na+ affinity of both NKA α1- and α2-isoforms, while increasing the Vmax of NKA-α2 (2). However, a role for PLM phosphorylation at the Ser63 site in relieving the NKA inhibition has not been demonstrated so far.
Here we determined the role of PLM phosphorylation sites (Ser63 and Ser 68) by measuring the effect of PKA and PKC activation on NKA function in HeLa cells stably expressing rat NKA-α1 with acute expression of PLM. HeLa cells have the advantage of being easy to culture and less problematic (compared to cardiac myocytes) for gene manipulation. For [Na+]i measurements, fluorescence signals were collected from a region containing ∼20 cells. Although we did not use a fluorescent tag attached to PLM to prevent contamination of the SBFI signal, parallel adenoviral infections with GFP included in the vector (but not fused to PLM) showed a high expression efficiency (>90%) and Western blot data indicated that the level of PLM was comparable whether infected alone or in the vector with GFP. Because only ∼90% of the cells used for [Na+]i measurements expressed PLM, the effect of PLM on NKA function measured here might be slightly underestimated. However, this does not affect the validity of our conclusions.
WT and mutant (S63A, S68A, and S63A-S68A double mutant) PLM were used here to determine how NKA was regulated by PLM upon Ser68 and Ser63 phosphorylation. WT and all PLM mutants inhibited NKA by decreasing the apparent pump affinity for internal Na+. This result is consistent with previous data in cardiac myocyte (2, 6, 11), Hela cells (12), and oocytes (1, 4).
Activation of PKA and PKC shifted the apparent affinity for internal Na+ of rat NKA-α1 in HeLa cells expressing WT PLM by ∼4 mM. This is comparable to what we found in mouse cardiac myocytes (2, 6). However, in a previous study (11), we found that PLM phosphorylation by PKC increased NKA activity, but via increasing Vmax, while the affinity for internal Na+ was not changed. The reasons for the lack of K0.5 effect in that study are unclear. PKA and PKC activation did not affect NKA K0.5 in HeLa cells without PLM or in cells expressing PLM with the Ser63 and Ser68 sites rendered unphosphorylatable (AA PLM). Thus, if PKA and/or PKC phosphorylate PLM at other sites, this has no effect on NKA transport function in HeLa cells.
PKC readily phosphorylates WT PLM at both Ser63 and Ser68 sites and mutant S63A and S68A PLM at the nonmutated site in HeLa cells (Fig. 5, A-C). Phosphorylation at only one site is sufficient for increasing the NKA affinity for internal Na+, as demonstrated in experiments with the S63A and S68A mutants, and the effect does not seem additive. Thus PLM phosphorylation at either Ser 63 or Ser68 is both necessary and sufficient to relieve the PLM-induced NKA inhibition.
PKA and PKC activation did not significantly affect the NKA maximum pumping rate under any condition. A previous study using 86Rb uptake (16) found that PKA and PKC modestly reduce the NKA Vmax in HeLa cells expressing rat NKA-α1 (by 22 and 27%, respectively). This effect might be due to NKA internalization and might have been enhanced in that study by the stronger kinase activation (1 μM PMA for PKC; forskolin plus IBMX for PKA) or their use of monensin as an ionophore. The lack of PKA and PKC effects on Vmax found here is in agreement with our own previous data in cardiac myocytes (2) and other data in oocytes (1) that show no Vmax effects for the α1-isoform of NKA. Both studies found, however, that PKC activation increases the Vmax of the NKA-α2, which may explain our previous finding that PDBu increases the total NKA Vmax in mouse cardiac myocytes (11).
In summary, we showed that 1) PLM phosphorylation at either Ser68 or Ser63 is necessary to fully mediate the enhancement of rat NKA-α1 activity induced by PKA and PKC activation; 2) PLM phosphorylation at other sites, if it occurs in HeLa cells, has no consequence on NKA function; and 3) PLM phosphorylation by PKC at either Ser63 or Ser68 is sufficient and redundant in relieving the NKA inhibition by PLM.
This work was supported by National Heart, Lung, and Blood Institute Grants HL-30077, HL-64724, and HL-81562 (to D. M. Bers) and the American Heart Association (to F. Han and J. Bossuyt and 0735084N to S. Despa).
No conflicts of interest, financial or otherwise, are declared by the author(s).
- Copyright © 2010 the American Physiological Society


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|The beginning of the Long Weekend.
|A gorgeous view at lunch
|I didn't want to leave after a few wines over lunch. :)
|I just love flowers of all kinds. :)
I went out to tea last night, and had a great time but I forgot my camera, and so did everyone else. Oh well . lol...
|Cloud moving in
Now it's dark, stormy, and raining. It's quite nice really. Time to snuggle up and finish that good book I'm reading.
Oh yes, and I did get very spoilt in the pressie department. :) Yah. lol.. :)
Have a good week
Bye 4 now. :)


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<< TK's MORNING BUZZ: 'Not Managing Your Rental Business Right?' E-mails Stream in From the Front Lines | Blog Home | TK's MORNING BUZZ: Pity the Poor VHS Rental Cassette -- Soon You Won't Be Able to Give Them Away! >>
APAR's WORKING WEEKEND: The WorldWideScreen Is Getting Bigger, and Smaller9 Feb, 2001 By: Bruce Apar
That advice would serve well one retailer who wrote a letter to Video Store that you can read in next week's issue. The degree to which this person was misinformed about the most fundamental tenet of video retailing -– First Sale –- admittedly left us speechless. The writer suggests that suppliers should exert control over the length of retailers' rental periods. Not his own rental periods, of course, only his competitors'.
As with that extreme example, thinking global can mean simply knowing the basics of the business you're in. Acting local is knowing how to apply them to your particular situation.
On a more literal scale, Video Store is thinking global by introducing a far-reaching, regular feature called WorldWideScreen, dedicated to reporting on home entertainment from America to Australia. By telescoping international coverage in this special department, our focus is to help readers everywhere add a world view to their own, local business.
American retailers who have mastered the art of networking -- through the Video Software Dealers Association and elsewhere -- already appreciate the value of sharing information with their counterparts from other U.S. markets.
Increasingly, telecommunications technology, especially the Internet, is making it easier and more advisable for video professionals to get together whether they reside in different counties or countries.
The closer we pay attention to how the business of home entertainment behaves in international territories, the more obvious it becomesthat merchants and suppliers the world over are not worlds apart.
In the United Kingdom, who else but Blockbuster has just gained more market share, snapping up another chain, Apollo. And like their American counterparts, British stores are grappling with revenue-sharing and the growth of DVD. On the other hand, Co Mast of retail chain Video Vision in The Netherlands tells us that revenue sharing works just fine for him.
Some countries can prove foreign even to Blockbuster. Pioneering American video retailer Jack Messer, a former VSDA president, gave the behemoth some big blues in Poland, where he runs a chain of stores named -- in the tradition of Philadelphia-based West Coast Video and Portland-based Hollywood Video -- Beverly Hills Video. Blockbuster stores veni, vidi, vanished.
The studios, of course, are global, too. U.S. distribution and Disney veteran Matt Brown moved from New England to Olde England to head international business for DreamWorks Home Entertainment. When we ran into him there on a recent trip, he told us he's having a bloody good time selling hits like Gladiator.
It often happens that policies not yet known in the United States are first introduced in international territories. Rental-priced DVDs from Buena Vista, Fox and Universal are causing a stir among U.K. retailers, while here the jury is out on the wisdom of a DVD rental window.
Two British faces familiar to many American video cousins are Vidbiz's Michael Senker, and Prime Time's Chris Simpson, frequent visitors to these shores to take our temperature regarding rental policies and politics. In fact, for years they have accurately predicted video trends in America -- including the adoption of copy-depth programs and the disappearance of studio exhibits at the VSDA convention -- based on studio decisions in their homeland.
All of the retailers mentioned above form a grassroots international alliance, that also includes Kevin Jellard of Australia's Movie Plus, that we will be consulting as an advisory board for WorldWideScreen.
To launch this ambitious round of global coverage, we are proud to align ourselves with the U.K.'s leading publisher of business-to-business home entertainment periodicals, Bleeding Edge/Columbus Group, a division of Highbury House. We will be working closely with Bleeding Edge editorial director Tim Murray to develop the most comprehensive international reports on home entertainment the world has ever seen.
After all, the goal is the same in every tongue: satisfy the customer and turn a profit. Hasta la vista.
Comments? Contact Bruce directly at:email@example.com


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VideoHive Family Christmas Letter 9796671
After Effects Project \ Openers \ Holidays
Christmas \ Letter \ Infographic \ Family \ Holidays \ Holiday \ Editable \ Travel
After Effects Project - Family Christmas Letter 9796671 by BlueWavePro @ VideoHive
After Effects Project \ Openers \ Holidays
Save on postage this holiday season! Send friends an animated Christmas letter! Styled like an infographic, this design includes 6 replaceable media and 35 editable text. Share your family's Top 5 Moments, your travel adventures, and more! No plugins required.
After Effects Version: CS3; Resolution: 1920x1080; File Size: 1000mb.
Animated Embellishments V1; Dubstep Action Promo; Gym Trainer Promotion; Bar Mitzvah Trailer Invitation; Corporate Office Logo Reveal; Fast and Modern Promo; Crowdfunding Campaign.
Keywords: bragging, Christmas letter, family, happy holidays, holiday letter, holidays, infographic, merry christmas, ornament, snow, snowflakes, xmas, year in review.


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It appears that your browser settings are preventing this page from loading the latest version. You may be seeing
old information or you may run into errors because of this. Your system time settings can also cause this issue. Please check that your system time is correct.
View full details at EstateSales.NET: https://www.EstateSales.NET/FL/Pensacola/32501/1380732
Everything must go... LIghts, Doors, Floors, Railings, Basketball Court Floor, Workout Equipment, Steam Generators, Pool Equipment and Ladders, Weights, exit signs, security system soo much more. Preview will be at 9am and Auction starts at 10am. We will be open till five pm so you can get your items out. The we will be open at 11 till 3pm on Monday the 12th. After that the building willl be torn down. Terms of sale Cash, Approved Check, Credit Cards. 12% buyers premium 2% discount for cash on the buyers premium.
Please come see us on Day 1. Feels like 154 great items.
End of Pictures
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Many people like to find several liquidation sales to go to when they are out and about. Here are some pages that might help:
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Discover Devonport
New Posters and Community Bunting - Devonport Arts Festival Update
Welcome to the Devonport Arts Festival update. The first bit of exciting news is that the new poster image for the 2014 Festival has been designed. I wanted it to be distinctly Devonport, whilst retaining a strong graphic feel and colour way. If you look closely, it also hints at a few of the exciting things you can expect to take place during the festival week.
One of these creative projects, which is underway right now is the Community Bunting project. I'm looking for hundreds of participants to join me in creating bunting flags of any type of creative material. They could be woven out of flax, or cut from painted bubble-wrap. Collaged, knitted, plaited or embroidered; you choose your medium, and make as many as you can. Each flag will be sewn together to create community bunting, and this will be raised along the length of Victoria road. So go to www.devonporartsfestival.co.nz for details on size specifications and collection points.
If you wish to be a part of the festival in others ways, be it organising an event, sponsoring an event, or simply helping out on the opening day, then please get in touch. I'd love to hear from you.
Toni van Tonder, email@example.com


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July/August 2014
Contributing Writers
Sanjeev Gunawardena
Sanjeev Gunawardena is a senior research engineer and co-principal investigator with the Ohio University Avionics Engineering Center. Gunawardena earned Ph.D. and M.S. degrees in electrical engineering from Ohio University, and was the 2007 recipient of the RTCA William E. Jackson Award.
Gunawardena's research interests include RF systems design, digital systems design, reconfigurable computing, and all aspects of GPS receivers and signal processing.
July/August 2014
A Universal GNSS Software Receiver Toolbox
May/June 2009
First Look
May/June 2009
Synthetic Aperture GPS Signal Processing


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"This recipe would be a great addition to any party or get-together. Feel free to add more jalapenos if you want more heat."
Spinach Dip With Pita Toasts
0 recipe photos
READY IN:45mins
Ingredients Nutrition
Spinach Dip
- 1 (10 ounce) package frozen chopped spinach, thawed
- 1 tablespoon chopped jalapeno
- 3⁄4 cup chopped onion
- 2 tomatoes, chopped
- 8 ounces cream cheese, softened
- 2 cups shredded monterey jack cheese
- 1⁄3 cup half-and-half
Pita Toasts
- 1⁄2 cup butter, melted
- 2 teaspoons lemon pepper
- 2 teaspoons cumin
- 6 pita bread rounds
- For the dip: Drain spinach and press out as much water as possible.
- Combine the spinach, jalapenos, onions, tomatoes, cream cheese, Monterey Jack cheese and half and half in a medium bowl and mix well.
- Spoon into a buttered baking dish and bake at 400º for 20 to 25 minutes.
- Serve with pita toasts.
- For pita toasts:.
- Combine the butter, lemon pepper and cumin in a shallow dish and mix well.
- Slit each pita bread round in half so you have 2 rounds.
- Cut each round into triangles (using a pizza cutter makes this very easy).
- Dip each piece into butter mixture and place on a cookie and put under the broiler until crisp.
get the genius kitchen app.
Watch on your iPhone, iPad, Apple TV, Roku, or Fire TV.Learn More


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TJ Drysdale - Fine Art Editing Tutorial
Welcome to my Fine Art Editing Tutorial! Whether you are a novice just getting your start in photography, or a seasoned professional looking to improve your workflow, this class will teach you how to unlock lesser known Photoshop tricks. This tutorial takes three of my images and walks you through every step I took to make the scenes in each photo come to life. Take advantage of all that Photoshop has to offer and get ready to learn the tips and tricks I have discovered for adding artistic effects to images!
The video is compatible with PC and Mac
You'll get 1 M4V
Mirror Links
[Tutorials] TJ Drysdale - Fine Art Editing Tutorial Fast Download via Rapidshare Hotfile Fileserve Filesonic Megaupload, [Tutorials] TJ Drysdale - Fine Art Editing Tutorial Torrents and Emule Download or anything related.


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Hi, I'm Krylyn…
Here is what you really need to know first and foremost about me…
I help people get out of their own damn way!
Plain and simple. And I came by this work the old-fashioned way…by getting the hell OUT of my own damn way.
Of course, that means I started off by being really superbly awesome at getting IN my own damn way. See if you can relate to any of this madness…
- Being a victim of my past programming that kept replaying really untrue, damaging messages like "you're not enough" and "you're not worthy"
- Allowing fear to dim my light, which kept me playing small and hiding in the shadows
- Blaming others for my circumstances and lack of progress
- Playing the people pleasing, gag-me-with-a-spoon "good girl"
- Trying to be "Super Woman" by not only taking on the weight of the world, but also refusing to let people help me (WTF?)
- Letting my inner critic run amuck and hijack my otherwise highly intelligent brain
- Settling for much less than I deserve (in jobs and relationships)
Does any of that shizz sound familiar? If so, then you and I speak the same language! And that is the language of FEAR.
Fear has been my biggest crutch…and my biggest catalyst.
I'm intimately familiar with fear. It's crept up in every significant event and area in my life. From surviving a family torn apart by alcoholism, undiagnosed mental illness, abuse, neglect, and divorce. To surviving a near fatal and quite rare auto-immune disease. To getting married…and divorced. To being on welfare and near bankruptcy. To raising a child with Asperger's Syndrome on my own. To getting my graduate degree. To re-careering…TWICE. To starting my own business. To walking away from a prestigious career as a psychotherapist.
Since we often teach what we most need to learn, I set off on a quest to tame my own fear. I was tired of allowing fear to hold me captive.
As I studied about fear, got some kick ass support, and took a long, hard look at my own life, I realized some pretty awesome truths:
- Fear lets us know where the edges of our passion lie. If there's no fear behind it, it's not worth pursuing.
- Profound healing often comes from small and subtle shifts in our perspective rather than huge epiphanies (although those are nice too).
- Healing is not a one-time event but rather an ongoing process. HINT: It's always about the process, not the outcome.
- Fear accompanies change and when harnessed well can actually skyrocket you faster and farther than you ever dreamed possible.
- Creativity is the cornerstone of all healing.
- Change is so much easier with support…the RIGHT KIND of support that challenges you and stretches you inside-out and beyond your comfort zone.
- There is greatness in everyone. It's just waiting to be acknowledged and let out of its cage.
I'm an author, speaker, coach, and singer/songwriter. I'm also a former psychotherapist, which gives me an edge in understanding human behavior and motivation. I am highly intuitive and have a way of helping people navigate out of the stuckness that holds them back and propel them into life-changing, positive action.
My passion is helping people tame their fears and get out of their own damn way so they can embrace their greatness, in life and in business.
I believe we all have a calling, which typically emerges from intense personal challenges.
As "The Fear Whisperer," I know what has held me back, and still holds me back sometimes. And there's a special place in my heart for those who, like me, have struggled with fear…cause I know what it's like.
But I also know the blessings on the other side and I love love love showing people what is possible (and witnessing their ah-ha moments) when fear becomes a friend rather than a foe.
Are you ready to change your relationship with fear and let your greatness out to play?
I would love the opportunity to help you get out of your own damn way. Let's book a time to chat about what's possible for you.
What else am I passionate about besides spreading the gospel about fear?
First, I love me my kidlet, Devan. It's been him and me for most of his life and I just love watching him grow and figure things out. He's super smart, creative, and funny…and probably one of the kindest souls you'll ever meet. He's a classically-trained musician (trombone) and a political activist for campaign reform and LGBTQ rights. One of our favorite things to do is quote lines from movies. We're just silly like that.
Second, I loves me my songwriting. Music has been a super important part of my life since FOREVER. I've been writing songs since age 8, released my very own CD, got to train with Grammy award-winning Bobby McFerrin, and still get out to perform from time to time (if even only at parties or on dates).
I also absolutely love dancing, visiting the ocean (and my sister in Santa Monica, CA), volunteering with at-risk youth, pampering myself with massages and pedicures, traveling, taking pictures of nature n' stuff, drumming, learning, and all things that involve me laughing and not taking myself or life too seriously.
Oh, and I can't forget about my big fluffity Fluff-N-Stuff kitty-face named Boomer (short for Boomerang). He keeps me company in my home office, curling up on anything I've left on the floor, and getting on his hind legs to pat me hello when it's time for some loves.


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We're excited to spend a few days in New Orleans at the Meeting of the International Neuropsychological Society. Ivy will be presenting her work on Frontostriatal Structural Connectivity in Autism Spectrum Disorder tomorrow, Thursday, February 2, 9:30-10:45 am (Poster # 58).
Dr. Signe Bray's work on brain development in children and adolescents is now online in Human Brain Mapping! Click here to read the abstract.
Data sharing in neuroimaging allows groups from all over the world to make use of unique data sets. We have a new paper out today that used anatomical, arterial spin labeling and functional data from the 'Pediatric Template of Brain Perfusion' study (http://palgrave.nature.com/articles/sdata20153). We found that although there were similar declining age effects on gray matter volume and perfusion, the spatial patterns of these changes were largely independent. This means that multimodal imaging is necessary to get a clear and accurate picture of how the brain matures, and also that models linking changes in volume with changes in blood flow and function are more complex than one might expect.
...for receiving an AIHS Postdoctoral Fellowship!
Aneesh's work on pediatric mild traumatic brain injuries is now online in Pediatric Emergency Care. Check here to read to here the new publication!
Congratulations to Dennis on passing his PhD candidacy exam!
Congratulations to Manu on winning 3rd place for best presentation at Neuron Night! She gave an interactive talk about her new research project: "The Effect of Transcranial Direct Current Stimulation on Reward Learning in Autism Spectrum Disorder."
Thank you to the Branch Out Neurological Foundation (http://www.branchoutfoundation.com/) for organizing a great event!
Manu will be giving a talk about her current research on: "Neural correlates of variable learning in adolescents with ASD." You can hear her talk on November 15th from 1:00-2:45PM in SDCC 2 (Session #: 578).
Keelin will be presenting a poster on: "Typical emotional processing of special interest stimuli in adolescents with Autism Spectrum Disorder." You can meet her on November 13th from 2:00-3:00PM.
...for winning this year's NSERC CREATE i3T Studentship and Queen Elizabeth II Graduate Master's Scholarship!
Congratulations to Keelin for receiving the award for an outstanding poster presentation at this year's Brain Development conference organized by NeuroDevNet.
Her poster showed data from her master thesis on 'Typical emotional processing of special interest stimuli in adolescents with Autism Spectrum Disorder.'
This summer, we went for a (steep? not so steep?) hike along the Ford Knoll Trail and had a delicious barbeque/picnic by Forgot Me Not Pond in beautiful K-Country.
The perfect farewell for our summer students and a well-deserved day off for all of us, especially for Keelin who successfully defended her M.Sc. thesis the day before! Congrats, again!
Christiane's work on attention development in the brain is now online in Cerebral Cortex (click here or on the picture below to get your free copy).
We investigated age-related changes in attention skills in 4-7 year old children and how they are reflected in the changes in an important attention network in the brain. We found for one, that as expected, all the types of attention skills showed age-related improvements - the 7-year-olds were better at it than the 4-year-olds. Interestingly, we also found that being better in one specific attention skill went hand-in-hand with increased cross-talk within nodes of the brain network independent of the children's age: selective attention. Selective attention is the type of attention that you need when you play "Where's Waldo?". It is also important for reading or math skills, and the way it develops has implications for children who aren't as good at it than others.
Christiane will be presenting a poster about her current research on: "Cerebellar functional connectivity predicts childhood ASD and ADHD traits".
Presentation time is Tuesday, June 28, from 12.45 to 14.45, though the poster will be up both Monday and Tuesday. Her poster # is 1107.
We're very happy that Manu's work on shape and volume differences in Autism Spectrum Disorder is now published in Neuropsychopharmacology. Feel free to check it out here or by clicking on the picture below. It's open access.
We collaborated with Dr. Mallar Chakravarty's group at McGill University who developed the MAGeT Brain algorithm for automated image segmentation. This allowed us to investigate volumetric and shape differences in a large pool of participants (N=757) taken from the Autism Brain Imaging Database Exchange.
We're very happy to have four motivated summer students in our lab this year! Kristina and Logan (middle and right, both Health Sciences) will be helping out with our ASD Learning study for which they will be using DTI and EEG. Anish (left, UAlberta) and Prayash (Biological Sciences) will be working with Christiane on our visual attention study.
Manu will be presenting her fMRI project at the 38th International Symposium of the Groupe de recherche sur le systeme nerveux central (GRSNC), "The neuroscience of decision-making".
Poster # 5, May 2 and 3, 12:45 - 14:00
...for receiving funding by the NSERC CREATE i3T Program! Christiane was awarded a postdoctoral fellowship and Dennis a graduate studentship.
The CREATE I3T Program is intended to prepare trainees to be future academic and commercial leaders, by providing them with cutting-edge technical skills and knowledge in Medical Imaging. Read more about it here.
Kari will be presenting a poster at the annual meeting of the Cognitive Neuroscience Society. You can meet her at the poster session on April 3rd, between 5-7 pm, where she will be presenting her work about associations between superior longitudinal fasciculus structure and attention skills in early childhood.
As part of the Child and Adolescent Imaging Research (CAIR) Program at the Alberta Children's Hospital, we are lucky to work together with four scientists who are specialized in pediatric neuroimaging. Check out the CAIR website here.
That also means great opportunities for socializing after work. We had our first CAIR social event last week.


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Quilt Racks and Blanket Holders
Nothing makes a Bedroom prettier than a Quilt rack or Blanket rack. It adds a homey touch when showcasing a hand-crafted quilt or hand crocheted afghan or bedspread. My Mom loved crocheting bedspreads and I still have the last one she made.
The Quilt or Blanket Rack can be much more than a convenience for storing bed covers. Since they come in all sizes, a small one would be super nice in a guest bathroom as you could hang several towels over the rungs.
Here in Arizona you might see an Indian Rug or other Native heirloom displayed on a Quilt Rack in the den or other prominent room in the home. Quilt and Blanket racks can display much more than a blanket or bed linen.
Check out these sweet Quilt Racks and find the perfect one for you!
J&J Wire Scrolled 2-Piece Quilt Rack
.Quilt Racks and Blanket Holders
Oh my goodness. This Quilt reminds me of one my Grandmother made. Isn't it the Wedding Ring pattern.
It looks very similar to my grandmother's but I do believe the rings were slightly smaller on her quilt.
These quilts are fascinating to me. Many hours of work but they last forever!
My Mom was a quilter too. Then she taught me to Crochet. And that was it.
When the weather is chilly, I like nothing better than a big pile of afghan in my lap…crocheting away.
King's Brand Antique Style Pewter Finish Towel Rack StandVintage Oak Quilt RackFrenchi Furniture Blanket/Quilt StandCoaster Home Furnishings 900833 Freestanding Towel Rack, Dark Bronze FinishIMAX Quilt/Towel RackMetal Lone Star Quilt RackWinsome Wood Blanket Rack, Antique WalnutJ&J Wire Victorian Double Quilt Holder with Shelf
Some folks prefer the "Hope Chest" or Cedar Chest at the foot of the bed
It was once a tradition for the mother to fill a chest of linens for her young daughter. When that daughter grew up and married, she would have all the lovely linens she needed.
The Hope Chest also Included many hand crocheted, embroidered and knitted things from the mother. A sweet, sentimental and lovely tradition.
Coaster Beautiful Storage Cedar Hope Chest, Deep Tobacco FinishCEDAR CHEST Paper PlansCoaster Cedar Wood Chest, Pine Finish with Hand Painted Floral Accents and Cushioned PadSeward Trunk College Dorm and Camp Storage Footlocker, Black, 30 InchCoaster Cedar Chest with Lock, OakCoaster Cedar Chest, Cherry


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By Spanishwhite - Sun Dec 20, 2015 2:59 pm
About us
Torrevieja Forum - Information coming soon!
Moderator: Moderator
sent at 10.56 and not one of them is correct ? :ro[…]
Now that is what I wanted to see ,a place where I […]
Sorry about your sad news. Kev
Thank you so much, this is what I have been lookin[…]
Bed Single or Iron


text: Originally subtitled A Sketch of the United States Government's Dealings with Some of the Indian Tribes, this 1881 work reviewed the history of battles and treaties with Native American groups, finding a trail of brutality, broken promises, and land grabs. Separate chapters chronicle the experiences of (in the book's usage) the Delawares, Cheyennes, Nez Percés, Sioux, Poncas, Winnebagoes, and Cherokees. Also included is a chapter detailing a number of massacres of Native Americans by whites. The appendix from the original edition has been omitted. Annotation ©2003 Book News, Inc., Portland, OR


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There ain't no cure for the bad co-signer credit score blues
Let's Talk Credit
Dear Let's Talk Credit,
How can I remove the information from my credit report due to the fact that I was the co-signer for a car loan? The main loan holder messed everything up. Was late on the payments, went into repossession, went back on payments and was late again. To make a long story short, I ended up paying off the balance of the car loan, because all of this was affecting my credit in a negative way very badly. I have a letter from the lender that the car loan was fully satisfied. What would be my next step, if there is any, to remove all that mess from my credit report? -- KG
Dear KG,
Unfortunately, accurate negative information will remain on your credit report for seven years from the first date of delinquency. Because you were a co-signer on the loan, you are jointly responsible for the loan. As a joint owner, the account information is reported to your credit file and the information cannot be removed by the credit bureaus until the reporting period ends.
By paying the balance due on the account, you have already done what you could to improve the situation. Doing so accomplished two things. First, the account is not being reported each month as past due by the lender. Second, although the account is still considered a negative account, it is paid in full. Most people have made mistakes with credit. Anyone viewing your credit report while this account is still listed on your credit will want to know that the account was paid.
The good news is that this co-signed account will have less negative effect on your credit as you move forward.
If you do decide to co-sign a loan for someone in the future, it is a good idea to keep track of payments on the account to assure that it does not cause problems for your credit. You could make it a condition with the other signer that if you co-sign he or she will keep you informed. You would then have the option to make a monthly payment for your co-signer if he or she was unable and avoid any late payments on your credit report.
Keep in mind that when you co-sign a loan with someone, you are agreeing to pay the loan if that person is not able. If you cannot afford the loan payments, you should consider saying no to any requests to co-sign.
Let's keep talking!
See related: Co-signer, joint account holder, guarantor: Know the differences, 10 self-defense steps for co-signers, Options are few when a co-signed credit card goes bad
Meet CreditCards.com's reader Q&A experts
Does a personal finance problem have you worried? Monday through Saturday, CreditCards.com's Q&A experts answer questions from readers. Ask a question, or click on any expert to see their previous answers.
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text: February 2017 NEWSLETTER, ISSUE 101 Sponsored by: Dear DiabetesSister, It's February, and we are reminded by the media of romance and hearts. At DiabetesSisters, we are thankful for the relationships we create and maintain, but also for the resources that allow us to keep our hearts healthy . We've taken this February eNewsletter issue and filled it heart healthy information just for you! We continue to recruit for our DiabetesSistersVoices research study, where we need women living with diabetes to register and share about living with diabetes. This study will help guide research for women and diabetes, a topic that needs to be in the spotlight. Please register today. We will be opening registration for our Weekend for Women Conference Series later this month. Please mark your calendar for October 13-15, 2017, in Alexandria, VA. This is exciting, as we have lined up a great faculty to bring discussions and education on topics such as Diabetes Technology, Heart Disease, Anxiety, Laughter with Diabetes, and much much more. You will receive a separate message with all details, so please be on the lookout for that in your inboxes. Finally, I'd like to take a moment and pay respects to a phenomenal woman who paved the way for many people living with diabetes. Mary Tyler Moore passed away on January 25, leaving behind a community of saddened, yet empowered people with diabetes. Mary was a force to be reckoned with - speaking on behalf of many of us when we didn't have a voice. As women, she taught us to live victoriously with diabetes, to show everyone what we are made of. I hope you will carry her legacy with you, as I do, and show the world that despite diabetes, we can "make it after all." Until next month, In Sisterhood, Anna Norton, MS CEO 23 Triumphant (NOT Perfect!) Years THRIVING with Diabetes LIFE CLASS WEBINAR: HEART HEALTH Diabetes affects 1 in 10 US adults and people with diabetes have a higher prevalence of heart disease and increased risk of heart attack compared to those without diabetes. In this webinar, you will learn about risk factors for heart disease commonly associated with diabetes and how you can decrease your risk of heart disease. Diabetes and Heart Health led by Sarah Alexander, MD, of Rush University Medical Center Wednesday, February 8, 4pm est All who register will be entered to win a copy of the American Diabetes Association's book Diabetes & Heart Health Meals for Two. Listen to our archived webinars and view our 2017 schedule SPONSOR SPOTLIGHT: WHAT IS HYBRID CLOSED LOOP TECHNOLOGY? THE MINIMED 670G SYSTEM. This post is sponsored by By Bonnie Goldberg, MA, RD, CDE Bonnie is a Registered Dietitian with a Masters Degree in Health Education from Columbia University. She specializes in diabetes care and has spent her career educating and empowering people with diabetes. She is proud to currently work for Medtronic. You might have heard about a new insulin pump that was recently approved by the FDA, the MiniMed® 670G system. This revolutionary new product is the world's first hybrid closed loop insulin delivery system. This groundbreaking new technology is the first and only system that constantly self-adjusts to automatically keep your sugar levels in range, based on how you live your everyday life. So, how does this new technology work? And how can it help you manage your diabetes better? How Does the Hybrid Closed Loop System Work? The MiniMed 670G system is the latest step in Medtronic's 35-year journey toward developing a fully automated, closed loop system. With each advancement made to our SmartGuardTM algorithm, Medtronic's insulin pump systems enable increased automation, requiring less and less interaction with the system. For example, in the MiniMed® 630G system, which launched in August 2016, SmartGuard technology suspends insulin delivery for up to two hours when glucose levels reach a pre-set low limit, reducing exposure to low sensor glucose events. We call this feature Suspend on low. CONTINUE READING DIABETESSISTERS TO DRIVE RESEARCH INITIATIVES: PLEASE REGISTER TODAY Along with The Johns Hopkins University School of Medicine, the University of North Carolina at Chapel Hill, and TrustNetMD, we are gathering women's voices on questions, resources, and thoughts on relevant health topics for women and diabetes via a new website: DiabetesSistersVoices. We invite all women over the age of 18, living with all kinds of diabetes, to register to the site and begin conversations with other women on life with diabetes, share resources, and pose pressing questions about the future of healthcare as it relates to life with diabetes. These contributions will shape the future of research, to be published in a final report, and distributed to healthcare providers. LEARN MORE ABOUT THE STUDY FROM ANNA NORTON AND KAREN GRAFFEO READ MORE ABOUT THE STUDY ON www.sixuntilme.com Your thoughts, questions, and resource sharing are integral to research on diabetes and women. Please register today at www.diabetessistersvoices.org. Funding for this project was awarded by the Patient-Centered Outcomes Research Institute (PCORI). DIABETES & HEART DISEASE: A HEART TO HEART WITH YOUR HEALTH TEAM Boehringer Ingelheim and Lilly have recently launched "For Your Sweetheart", a U.S. initiative to raise awareness of the link between diabetes and heart disease and to encourage people with type 2 diabetes to know their heart disease risk and speak to their healthcare provider, for the sake of their health and the people they cherish the most. This month, we invite you to learn how to speak with your healthcare provider about the risks of diabetes and heart disease. Below are some questions to help you start the conversation: Do you think I am at risk for a heart attack or stroke? If I already take a medication for my heart, am I still at risk? What lifestyle changes can I make now to lower my risk for heart disease? CLICK HERE TO LEARN MORE Please consider using this link for a portion of your sales to impact DiabetesSisters. SHOP FROM THIS LINK RECIPES TO FEED YOUR HEART The American Heart Association reports a misconception that anything described as healthy lacks flavor and satisfaction. There is also an assumption that healthy foods are expensive; however, there are many creative ways to cook up a delicious, heart-healthy dish. Below, we have highlighted some of our favorite recipes from the American Heart Association Go Red for Women campaign. Bon appetit! Pan Seared Chicken Breasts with Creamy Mushroom Sauce Turkey Chili Honey and Spice Pears Source: American Heart Association RECAP: KICKING OFF THE YEAR WITH A NEW YEAR'S HEALTH REVOLUTION Last month, we kicked off the new year with the Healthy Temple Ministry at Mt. Jezreel Baptist Church in Silver Spring, MD. The New Year's Health Revolution met women living with, or at-risk of, diabetes for a day of education. CDE Janice Harris from Howard University Diabetes Management Program shared how women with diabetes should care for their bodies from head to toe. This comprehensive session focuses on self-management strategies to keep us living well, with an emphasis on how healthy blood flow is critical for proper brain function. The day also included a physical activity session, focusing on chair exercises and basic martial arts techniques. The day concluded with information on healthy snack options. DiabetesSisters is grateful for the support of Big Blue Test, Janssen and Novo Nordisk as we continue to reach African American and Hispanic women throughout the country. If you are interested in learning more about our Minority Initiative Program, please email us at firstname.lastname@example.com. DiabetesSisters helps to connect women living with diabetes through peer support, education, and advocacy that improves their health and quality of life. We invite you to be part of expanding that network of sisterhood and strength by joining our new Sister Strength Monthly Giving program. BECOME A SISTER STRENGTH MONTHLY DONOR Since 2008, your dollars have allowed us to continue to grow our signature programs such as the PODS Meetup program, which reaches over 1,200 women annually, as well as maintain our online programs such as this e-newsletter and our website, which hosts over 440,000 visitors each year. Programming in 2016 and beyond will continue with existing and new programs, but we desperately need your support. Set up your monthly gift today: Together we will build a stronger future for women with diabetes! PLEASE SUPPORT DIABETESSISTERS TODAY VISIT OUR EDUCATIONAL LIBRARY Click HERE to visit our growing library where you can download, print, and share this information. The creation of many of these educational pieces were a result of the generous support of our Advisory Council and industry partners including AstraZeneca, BI, Center for Hope of the Sierras, Dexcom, Janssen Pharmaceuticals, The Leona M. and Harry B. Helmsley Charitable Trust, Lilly, Merck, MicroMass Communications, Novo Nordisk, and Regeneron. sisterTALK Blogs Explore tips from our experts and stories from women like you who live with diabetes. Get connected, then join the discussion. Meet Our Bloggers featured blogger sponsored by Are You For Real?! healthy living Why Some Types of Exercise can make Blood Sugar Increase Why Moderation Was Never the Answer nutritionMatters of the Heart with Diabetes type 1 Chin Up, Buttercup! Keeping Those Resolutions type 2New Year, New Me? What is Your Health Mantra for the New Year? perspectives A Fresh Start Arlington, VA February 2, 7pm Chattanooga, TN February 2, 6pm Ventura County/San Fernando Valley, CA February 6, 6:30pm Rochester, NY (Westside) February 6, 6pm Rochester, NY (CollegeTown) February 7, 6:30pm Princeton, NJ February 8, 7pm Greater Philadelphia, PA February 9, 7pm Durham, NC February 9, 6:30pm Apex, NC February 15, 6pm Boston South Shore/BraintreeFebruary 15, 7pm Chesapeake, VAFebruary 16, 6:30pm Jacksonville, FLFebruary 16, 6:30pm VIRTUALFebruary 16, 8pm EST Williamsburg, VAFebruary 21, 6pm Greensboro, NCFebruary 21, 6pm Rochester, NY (Eastside)February 21, 6pm Richmond, VAFebruary 21, 6pm Reno, NVFebruary 21, 6:30pm Boston (Metrowest)February 21, 7pm Albany/Schenectady, NY February 28, 6:30pm ----------- Want to learn more about or attend a local PODS Meetup, or start a PODS Meetup where you live? Want to find out about the Virtual PODS Meetup? Please fill out our PODS Meetup info form. LILLY ANNOUNCES PLAN TO OFFER INSULIN AT DISCOUNTED PRICES Lilly has announced plans to work with Blink Health to offer lower priced insulin to those who may be paying full retail prices at their pharmacies. The discounts may reduce costs for people who pay full retail prices at the pharmacy, such as those who have no insurance or are in the deductible phase of their high-deductible insurance plans. LEARN MORE ABOUT THE PROGRAM Diabetes Health Magazine Designed by a woman living with diabetes, FreeToGo offers clothing, jewelry and accessories for people living with diabetes. FreeToGo has committed a portion of their sales to DiabetesSisters. Visit them at www.freetogostyle.com FreeToGo PRODUCTS Designed by a woman living with diabetes, FreeToGo offers clothing, jewelry and accessories for people living with diabetes. FreeToGo has committed a portion of their sales to DiabetesSisters. Visit them at www.freetogostyle.com STAY CONNECTED


text: Human Rights Observatory State TV: UN Nuclear Chief Expected to Visit Iran Next Week U.N. nuclear agency chief Yukiya Amano is expected to visit Tehran on Nov. 11, Iranian state television said on Tuesday, a possible sign of progress in a long-stalled investigation into suspected nuclear arms research by Tehran. After years of worsening confrontation with the West, Iran has switched to a conciliatory mode - entailing diplomacy in search of a peaceful solution to its disputed nuclear activity - since the June election of moderate President Hassan Rouhani. The International ...Read complete article© Voice of America - Tuesday, November 5, 2013


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text:
Demonstrators may be asked to leave St. Paul's in London
St. Paul's Cathedral raises doubts over protesters
Local churches in Joplin help to rebuild houses with "Extreme Makeover: Home Edition"
TV makeover show to build 7 homes in Joplin
Afghanistan lack in religious liberty
Watchdog group laments lack of religious liberty in Afghanistan
< Chinese In Space
Jun 11, 2013 06:46
Category: General News
Category: General News
Immigration Front & Center Today
WASHINGTON (AP) — Both the White House and Capitol Hill will be focused on the immigration overhaul today. President Barack Obama is inviting law enforcement, labor and business leaders to the White House to show their support an immigration overhaul. In the Senate, procedural votes are scheduled to officially allow the debate to move ahead.


text:
« view all Gay Boracay • Hotels
Calle Trinidad, Station 2, Boracay, Philippines | map | directions
Why this hotel? Good, quiet location. Walk to White Beach and D'Mall. Great value for money. Free WiFi.
8.8 Excellent - based on 413 Agoda reviews
Excellent, new resort with no frills. The Blue Marina Boracay is located on a quiet alley in Station 2, about 10-15 minutes' walk to White Beach and D'Mall with all its shops and restaurants.
Guest rooms are modern and clean. Each has a flat screen satellite TV, free WiFi, large bathroom with shower, and safe. Nice breakfast breakfast is served at its sister resort, COAST Boracay (a 10-minute walk).
We've stayed here and enjoyed the convenient location and friendly staff. Reasonable price, too!
venue: hotel (旅馆) | features: cafe, free wifi (咖啡馆)
corrections | add an event | last updated: 28-08-2017
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text:
YOU ARE VIEWING : STORAGE WATER HEATER (6 Litres and above)
India's first intelligent water heater is here! Bring home the new revolutionary water heater Verano with an intelligent scheduler and automatic failure notification. Now set the temperature of your heater from absolutely anywhere in the world!
(Metallica & Non-Metallica)
Welcome the hot new model from the V-Guard Water Heaters range. Available in the market in two variants called Pebble and Pebble (Metallica), these water heaters come in 6 different colours.
Steamer Plus EPAC
Kick start your mornings or rejuvenate yourself after a hard day's work with the sturdy and beautiful V-Guard Steamer Plus EPAC. With its simple yet striking design, reliable performance and high energy efficiency, this water heater is a perfect match for modern bathrooms.
Sprinhot Plus
Relax to a soothing and warm water bath after a tiring day using this amazing water heater. We at V-Guard call it the Sprinhot Plus but you can call it your own personal spa.
Steamer Series
Need hot water at the flick of a switch? Get a water heater from the Steamer Series today. It provides you with perfect temperature water and also helps you save on your electricity bills.
Steamer Plus MS
The Steamer Plus range of water heaters features V-Guard's innovative high quality heating element, it has an inner tank made of steel and provides high energy efficiency.
Steamer Plus MSV
This range of V-Guard water heaters is characterized by aesthetic design, a high level of user convenience and economical operation.
Steamer Plus MS Sleek
A revitalising bath is an experience that everyone loves coming back to during winters. Turn it even more beautiful by introducing the Steamer Plus MS Sleek water heater as a companion.
Steamer Plus MSH
Treat your body to a hot water bath experience using your suitable pick from V-Guard's Steamer Plus MSH water heater range. This water heater adheres to the highest standards of safety.
Krystal Plus
After a long day at work, a hot water bath is all you need and this is where the Krystal Plus comes into action and gives you a chance to indulge in a therapeutic experience.
Know the difference between Sine wave & Square wave.
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Need help finding the best inverter for your needs? Calculate your power needs here and we'll help you select the right product.
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Need help finding the best inverter for your needs? Calculate your power needs here and we'll help you select the right product.
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General Question
Do the magnetic stips on hotel room cards contain all your personal details?
Asked by pussinboots (213) March 12th, 2012
I heard that the magnetic strip issued by hotels as a room charge key contains all your personal details including credit card/debit card details . Is this true ? I never hand my room key back when I leave for exactly the reason above it only takes a batch to be thrown out in the trash or a dodgy employee to pass it on to a fraudster,though I must say I dont know if its an urban myth or not. Could anyone confirm either way please?
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Qmobile Q70 Price In Pakistan. Qmobile Q70 is a Dual SIM Candy bar, Touchscreen Phone from Qmobile which runs on China Mobile OS. Qmobile Q70 accessible in White color and 91 grams of weight. Qmobile Q70 has 240 x 320 pixels, 2.8 inches presentation measure which upholds TFT resistive touchscreen, 256k colours. qmobile Q70 has GPRS, WI-FI, Bluetooth connectivity choices ready for. You can take pictures of your valued ones from its 2.0 MP Camera.
- Wi-Fi 802.11 b/g/n
- micro USB
- SMS, MMS, Email
- MSN Messenger,Yahoo Messenger,witter,Youtube
- Google Talk, Google Search, Google Map, Facebook
- Vibration / Ringtone Mp3
- Video Supports AVI, Mp4,3GP


text:
Videos Invisible Agent likes
Evolving organic creatures in an alien atmosphere. Where liquid rises in dark empty space and we are drawn to the 'other side'. A perfect symbiosis, between 3D animation and ambient electronic…+ More details
Browse LikesLikes
Likes are an easy way to keep track of the videos you enjoy. Use likes to bookmark videos you want to watch again and again and again and again.


text:
Industry News
Orlando's Caregiving Thought Leaders to present at June 29th Seminar and Lunch
Prominent Orlando caregiving experts will answer questions from families during June 29th Fearless Caregiver Conference in Maitland. Complimentary tickets are available for family caregivers. CEU's are available.
June 17, 2011 - PRLog -- Today's Caregiver magazine and FearlessCaregiver.com, the nation's foremost print magazine and Web community for family and professional caregivers since 1995, announces the presenters of the Orlando Fearless Caregiver Conference on June 29th in Maitland. These community, healthcare, insurance, mobility and mental health experts will spend time with family and professional caregivers answering their questions during the daylong seminar and lunch. Complimentary tickets are still available for family caregivers. CEU's are available for professional caregivers. Registration online at FearlessCaregiver.com or call 877-829-2734 for tickets.
Prominent Orlando Caregiving Experts to lead the 109th Fearless Caregiver Conference June 29 at the Holy Trinity Reception & Conference Center, 1217 Trinity Woods Lane in Maitland include:
Randy Hunt - Senior Resource Alliance - Chief Executive Officer
Mary Ellen Grant - Share The Care, Inc. - Chief Executive Officer
Dr. Scott Latimer - Humana - Market President Senior Products West Florida
Lori McKewen, RN, BSN - WellMed Medical Management Inc - Care Team Manager
Dr. Denise Clark - VITAS Innovative Hospice Care - Associate Medical Director Central Florida
Mearlene Filkins LCSW - Veterans Administration Medical Center - Caregiver Coordinator
Reinhart Wiegand - Molift Inc. - President Chief Executive Officer US Division
Dr. Jamie Huysman PsyD, LCSW, CAP, CFT - Today's Caregiver magazine - Professional Issues Editor
Professionals wishing to register for the CEU track led by Dr. Jamie Huysman can register at FearlessCaregiver.com.
Registration Includes lunch: Register at FearlessCaregiver.com or by calling (877) 829-2734.
"In 14 years and 107 afxym previous Fearless Caregiver conferences, I am hard pressed to remember an event where so many caregiving experts have joined us for the day to support area caregivers."
Supporting the celebration are leading care organizations including Humana, Wellmed, Molift and VITAS Innovative Hospice Care, among dozens of other exhibitors and resources. More than 38,000 family and professional caregivers in 24 states have learned how to be a Fearless Caregiver Advocate for their loved ones, clients and themselves at a Fearless Caregiver Conference.
What Support Is Available For Florida Family Caregivers?
The financial decisions made at the state level have enormous consequences to the two million caregivers living in Florida. Join caregiving experts for the day to learn how these decisions will affect you and what support will be available as you care for your loved ones.
Barg added, "The most recent Fearless Caregiver Conferences in South Florida, Connecticut and Minneapolis were tremendous successes with hundreds of family and professional caregivers participating in full-day events where they received answers to their caregiving questions from physicians, spiritual leaders, and healthcare experts in topics such as Alzheimer's, MS, cancer, autism, stoke, Social Security, Medicare, diabetes, incontinence and Parkinson's throughout the day".
Fearless Caregiver Conference participants will learn:
• What support is available for Central Florida family caregivers
• Where the money is for caregivers
• How to partner with their family members
• How to ask questions of healthcare leaders in the area
• How to get a loved one to stop driving
• Share information with their fellow caregivers
Who Should Attend?
• Children of aging parents
• Parents caring for children
• Spousal caregivers
• Long-distance caregivers
• Grandparent caregivers
• Pastoral caregivers
• Volunteer caregivers
• Professional caregivers
• And anyone else seeking hands-on advice
Sponsorship opportunities are still available. Call (800) 829-2734 for information and to reserve your space.
# # #
Established in 1995, Caregiver Media Group has become the recognized media authority on caregiving through Today's Caregiver magazine, Caregiver.com, the Fearless Caregiver Conferences, the award winning book The Fearless Caregiver: How to Get the Best Care for Your Loved One and Still Have a Life of Your Own, as well as Caregiver Media Group's award winning content and custom publications.
Today's Caregiver magazine contains cover interviews with celebrity caregivers, articles on caregiving issues and vital resources for all caregivers. Cover interviews have included Leeza Gibbons, Clay Walker, Kathy Greenlee, Debbie Reynolds, Dixie Carter, Debbie Reynolds, Della Reese, Linda Dano, Robert Urich and Clay Aiken. The digital version of the magazine is available free of charge at Caregiver.com.
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text:
- Please select a date to see the proper prices!
Description of the accommodation:
Rooms, services Guests looking for accommodation in Cabo de Santo Agostinho are welcome to book 300 nicely furnished rooms at Vila Galé Cabo Cape of Saint Augustine. You are also welcome at the villa for a fine local meal in the restaurant. For those arriving by car parking is available nearby. A great opportunity to do sports will be provided by the local gym. The bar provides a nice atmosphere for a romantic evening talk or a personal meeting. In the safe your valuables may be the safely secured. If you have a suitable portable device, you can connect to the Internet via a wireless network (WiFi) available at the villa. The exact scope of services offered by Vila Galé Cabo Cape of Saint Augustine (including those for an extra fee) is available on the information sheet below.
Payment Depending on the selected date, room and price, you may need to provide credit card guarantee or advance bank card payment to finalize your reservation.
Arrival, opening hours The earliest time to check in at the villa is 15:00, the latest time to check out is 12:00. The personnel can communicate with you in the following languages: Portuguese - Portugal and English.
Vila Galé Cabo Cape of Saint Augustine rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Free WiFi in shared places
- Steam room
- Pool (Outdoor - seasonally open)
- Finnish sauna
Garden, Bar, Elevator, Safe deposit box
Own restaurant
Child supervision, Playground
Hairdryer, Desk in the room, Mini-bar