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Teleport to Stirk
Oblivion » Magic - Spells & Enchantments
Oblivion » Magic - Spells & Enchantments
Added: 10/02/2014 - 09:56AM
Updated: 10/02/2014 - 09:56AM
Last updated at 9:56, 10 Feb 2014 Uploaded at 9:56, 10 Feb 2014
I made a small mod that just adds a Teleport to Stirk spell that can be purchased from Thaurron, the Bosmer in the Anvil mage's guild. It sends you directly to the lighthouse. I made this specifically for my RP character who does not fast travel except by portals such as Frostcrag Spire. Someone hopefully finds this useful. Lol


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Junior PF (Kansas) 6'9" 240 lbs. DOB: 3/18/1991
ESPN Profile (Insider)
NBADraft Net Profile
Draft Express Profile
2010-2011 Season: 33 games, 7.6 points, 6.4 rebounds, .6 assists, 1.3 turnovers, .4 steals, .7 blocks, 60.1/51%
July 8, 2011
Robinson played limited minutes behind the Morris twins as a freshman and sophomore, but should see a drastically increased role in '11-'12. He's very physical and has an NBA body. He is still very inexperienced, but could develop into a better player than either Morris twin. He's a great rebounder and uses his body well to create space.
Robinson played only 14.6 minutes per game last season but will be the focal point of Kansas' team as a junior. He has already proven that he can hold his own defensively, but his offensive development should be watched closely. Expect him to be similar to Marreese Speights at the NBA level.

subset: commoncrawl


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NEW YORK (TheStreet) -- Investors aren't ignoring Ukraine risks, say cashtaggers on StockTwits.com. The economic fallout of the West's limited response to Russia's annexation of Crimea is largely priced-in -- even for Russia.
Year-to-date the SPDR S&P 500 (SPY) is up 1%. Market Vectors Russia (RSX) is -20%, iShares MSCI Emerging Markets Index (EEM) -5% YTD.-- David Shvartsman (@FinanceTrends) March 26 at 12:03 p.m.
The S&P 500 and Dow (DIA) edged lower by mid-afternoon Wednesday after President Obama's fighting words for Europe. At a news conference after meeting with Western leaders, the president pressed European nations to spend more on defense in order to curb an expansionist Russia. The Nasdaq (QQQ) lost nearly a percent amidst talk of frothy tech valuations.
Market Vectors Russia, an ETF that tracks the performance of Russian stocks, gained 0.5% midday. Meanwhile, Direxion Daily Russia Bear 3x (RUSS), a 3X levered ETF inversely related to the performance of Russian stocks, fell more than 2%, sparking debate and earning it a spot on the StockTwits' trending bar, which tracks the most discussed tickers.
Market Vectors Russia, Direxion Daily Russia Bull 3x (RUSL) expecting profit about 5x risk if prices return to low normal 2013 range, hedged on the downside.
-- Market Collab (@marketcollab) March 25 at 01:04 a.m.


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Talent pipeline gets squeezed
Nicolas Borit, Dragages Hong Kong's managing director, says to maximise talent flexibility and provide employees with job security, young engineers who join Dragages learn competency skills in civil and building techniques.
"Whenever infrastructure projects are in a civil or building phase, we have the professionals in place to provide the solutions," he says, adding that the strategy also ensures a stable workforce and sustainable pipeline of engineers.
Typically, graduate engineers who join the firm spend the first four to five years rotating between projects, learning civil and building engineering skills. Echoing the prevalent industry view, Borit says the sector needs more talent.
According to the department of civil and environmental engineering at the Hong Kong University of Science and Technology, graduates of the bachelor of engineering in civil and structural engineering have excellent opportunities to work in a range of areas, such as government departments, engineering consulting industries, construction firms, and international engineering industries.
A civil engineering education is also a good foundation for careers as middle- to top-level managers, as well as sales and technical representatives.
Professor Sean Tang, associate dean for research at the Chinese University of Hong Kong's (CUHK) faculty of engineering, sees plenty of jobs from cross-border co-operation with mainland firms that have recently located in the Hong Kong Science Park.
Hence, the CUHK has established new offerings such as a master of philosophy and doctorate in biomedical engineering.
"Biomedical engineers are key in designing innovative medical instruments and sensors, deploying the emerging information infrastructure, creating new biomaterials, and developing medical biotechnologies," says Tang.
Meanwhile, as Hong Kong's bourse seeks to entice mining firms to list on the city's stock exchange, experts say potential mining engineers could be missing out due to a lack of university programmes locally.
"There is such a demand for mining engineers, geologists and people with mining qualifications in China," says Paul Fowler, a director with Hong Kong-based Rockhound, which provides technical valuations and services to the mining, energy and natural resources industry in Asia Pacific.
"At the moment, Hong Kong is not producing anyone through the universities who is capable of taking advantage of the opportunities that exist on the mainland where Chinese language skills are a must," says Fowler.
Joseph Pui, also a director with Rockhound, says Hong Kong should have the human engineering software to meet growing developments.
"Engineers working in the mining, energy and natural resources sector are exposed to a range of environments and challenges. The work can be very rewarding," says Pui.
According to speciality chemicals company Lanxess, continued demand from the mainland's chemical industry will fuel strong growth and demand for chemical engineers.
To recruit and retain workers, Lanxess provides various talent development activities as well as its Lanxess Academy, set up to "[allow staff] to take ownership of projects and give them the opportunity to develop new skills, [so they can] show the company what they can do," says a Lanxess spokesperson.


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Attention all kung-fu masters, "Black Dynamite" is coming back!
After a long period in development, Adult Swim has finally given the greenlight for an all new "Black Dynamite" animated series coming in Spring 2012.
"Black Dynamite" is based on the Scott Sanders directed movie of the same name which starred Michael Jai White in the title role as an "ex-CIA agent and full-time ladies man." In the original film, Black Dynamite pursued the deadly conspiracy of Anaconda malt liquor from Kung Fu Island all the way to President Nixon's White House.
White will reprise his role in the animated series alongside other returning cast members, Tommy Davidson, Kym Whitley and Byron Minns. Carl Jones ("The Boondocks") will be spearheading the series, which will be animated by Titmouse.
Jon Steingart and Jillian Apfelbaum will also join Jones as executive producers for the series, with Brian Ash as a co-executive producer. Sanders, White and Minns are also producers on the show.
While the "Black Dynamite" animated series is over a year away, "Black Dynamite" currently lives on as a new comic book one-shot from Ape Entertainment called "Black Dynamite: Slave Island." In the comic, Ash adapts a story by White, Minns and Sanders that brings Black Dynamite to a mysterious island where slavery is still in effect… but not for long.
The "Black Dynamite: Slave Island" one-shot is currently out in comic stores, with art by Jun LoFamia and colors by JM Ringuet.


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Maryland Bat Removal
This is a comprehensive list of Maryland bat removal and bat control companies. These companies follow best practices when performing Maryland bat removal, bat proofing, bat guano removal and disposal, and bat bug treatment and extermination if needed.
We ask that all bat removal companies in Maryland operate in accordance with NWCOA Bat Standards, remove bats humanely, and don't remove bats during the bat birthing season.
All bat removal companies in Maryland should be properly licensed, guarantee their work, and carry required levels of liability and workers' compensation insurance.
We try to ensure that all Maryland bat removal companies appearing on this website are the area's best local company for getting rid of bats.
If you have bats in your attic, a bat in your house, or bats in your home's vents, give us a call for Maryland bat control and removal.
Our Maryland bat removal companies are experts at getting rid of bats in Maryland and keeping them out.
Bat Guano Removal In Maryland
Bat guano may contain the Histoplasmacapsulatum fungal spores. Inhalation of these spores can cause a lung illness called Histoplasmosis.
Bat guano removal in Maryland should only be performed by companies with the training and equipment needed for safe removal and disposal.
Bat Bug Removal In Maryland
Bat bugs are closely related to bed bugs. Bat bugs, like bed bugs, are parasites that feed on the blood of their host. They so closely resemble one another that enhanced magnification is needed to make a positive identification.
Bat bug extermination and treatment in Maryland should only be performed by trained professionals.
Bat Control In Maryland
Bat control in Maryland can be difficult at times. There are many different techniques and approaches that can be utilized depending on your particular bat removal needs. We recommend only using Maryland bat removal professionals to get rid of your bats.
Bat Diseases In Maryland
Bats like other mammals are associated with certain diseases that may be transferable to humans. The main problems associated with bats are rabies, histoplasmosis, bat bugs, and the damaged caused by allowing bats to remain in Maryland structures.


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Tucson Police Department officers responded a 911 call regarding a shooting incident that occurred at a residence in the 10500 block of East Bridgeport. Upon arrival, the officers encountered an woman who had just shot her husband.
Susan Thacker, age 58, was waiting for police outside of the residence. She advised them that her husband was inside the residence and also advised that he had been shot. The officers checked the interior of the residence and found Gregory Thacker, age 58, who had obvious signs of trauma. Mr. Thacker was pronounced deceased at the scene.
Detectives learned that Mr. Thacker and his wife, were both inside the residence on the evening of June 17, 2013. The couple engaged in a verbal argument, which escalated to a lengthy confrontation, lasting a few hours. Ultimately, Mrs. Thacker discharged a weapon that was in the residence at Mr. Thacker. He was struck by the gunfire and succumbed to his injury. She called 911 to report the shooting at approximately 9:05 p.m. It appears that Mr. Thacker and Mrs. Thacker were the only people inside of the residence when the incident occurred. Mrs. Thacker was ultimately arrested for 1 count of Second Degree Murder, a felony offense.


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Write the Docs NA
Write the Docs NA is a conference that focuses on documentation systems, tech writing theory, and information delivery.
This conference creates a time and a place for the North American community of documentarians to share information, discuss ideas, and work together to improve the art and science of documentation.
We hope to see you there!


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Rolling through the Rockies
Moments into the Rocky Mountaineer train trip and I could be forgiven for thinking my window is a giant TV showing a nature documentary.
"That's just AGM," my new American friend Bob says as we step onto the coach's outdoor vestibule on this pale grey morning in October.
"Annual general meeting? I ask.
"No, just another gorgeous mountain," he laughs.
I didn't know the American vernacular had an acronym for this western Canada phenomenon.
But Bob and I soon agree that this snow-topped peak - Mount Cheam - is not the run of the mill AGM, it's an absolute knockout.
The brochure suggests that during our two-day journey from Vancouver west to Lake Louise, with a stop in Kamloops on the way, we'll see a myriad of majestic mountains - and it promises we'll have "a life changing experience".
First impressions are positive: the trip begins with a 6am wake-up call, a clerk sporting a dark grey blazer assigning boarding cards in the lobby of the Georgian Court Hotel and a short bus transfer to a bustling, airport-style station.
"All aboard," comes the clarion call.
Red walk-on mats materialise in front of each coach, staff buzz about showing guests to their carriages and before I can take another souvenir snapshot of the huge, shiny blue train, I'm ensconced in seat seven in Gold Class (there's also Silver and Red classes). In seat eight is my travelling companion, my mum.
"Well this is different to CountryLink," Mum says, as I take in the details of the coach: glass-dome roof; plush seats with loads of leg room; huge windows; and a spiral staircase that leads down to a white tablecloth restaurant.
Within minutes Zac, one of the four attendants in our carriage, arrives with a mimosa.
We chink glasses. By the time our flutes are empty we've met Bob from Boston, accompanied by his adult daughter; to our left we chat to Myrtle, an octogenarian travelling alone ("I've come to see the leaves changing in the fall"); and behind our seat is Jay from Korea. His wife and little boy, struck by jetlag, are fast asleep, rocked like babes in their cradles.
Unlike some of the world's famous train journeys guests don't sleep on board the Rocky Mountaineer (save for naps).
At dusk each night the train pulls in to its destination and seamlessly transports passengers by bus to their hotel.
While Jay's family snoozes we pop down to the restaurant, which serves breakfast and lunch at tables set for four. The menu is regionally-inspired and whipped-up to order in the galley kitchen.
Lunch is lightly roasted wild Sockeye salmon for me, vegetarian farfalle for Mum, and glasses of gewurztraminer from Okanagan winery Wild Goose for two.
The salmon is bold, salty and as exquisite as our surrounds.
Snug in our old-worldly, elegant coach, we scan the treacherous terrain for grizzly bears.
There's an abundance of Canadian creatures outside but giant, furry bears are few and far between.
In the dolphin-grey sky a kettle of bald eagles soar. In the shallow riverbeds there's salmon. Dead. Dead? It's not something I'm used to seeing.
An article in the Rocky Mountaineer Mile Post newspaper sheds some light on this shocking scene: "The salmon only survive a few days after spawning before decomposing and washing up on the riverbanks," it says - (note to self, watch more David Attenborough).
After one day our "seen-it-done-it" list contains bighorn sheep, elk, moose and deer, but the only bears I expect we'll see today will be in our dreams after we bed down for the night at Hotel 540 in Kamloops.
The alarm rings out again at 6am, we bounce out of bed ready to embrace day two and soon enough we're dining on eggs benedict.
The atmosphere on board is jovial. It's as though everyone has known each other for years: the majority of passengers are from Australia and America, except for Jay's family, who are flying the only flag for Asia - and for children.
Two-year-old Philip is the one little person on board, lifting the mood even higher with his adoration of trains.
The scenery with every kilometre clocked gets bigger and better. Our precious few hours on board passes by in a blur of waterfalls and river rapids.
The further we go, the more we all transform into little Philips. Our childlike wonder reaches a crescendo when we pull in to Lake Louise. The Fairmont Chateau Lake Louise. Is it real or a picture from a fairytale book?
I squeal when I see it. "Awwww," Bob says. "Simply magic", Myrtle adds.
We're all dazzled, delighted and dazed as we try to listen to our guide Harper as she tells us about the area. There's so much to do, she says: shopping, dog-sledding, canoeing, being pampered, exploring the hiking capital of the Rockies.
I wonder if Bob will be joining us tomorrow on our tour of AGM?
Early the next morning, as a bunch of newly formed friends gather for the climb up to Lake Agnes atop a nearby peak - Bob strangely is no where to be found, he might be the only one in the group who is tired of another gorgeous mountain.
GETTING THERE: Air Canada operates flights to Vancouver. See: aircanada.com. See House of Travel for Canada deals.
GETTING AROUND: Rocky Mountaineer offers over 45 holiday packages and five unique rail routes. This year it launched the Coastal Passage, a new route connecting Seattle WA and the Canadian Rockies - it's the company's first rail journey to and from the US.
Rocky Mountaineer has extended its early booking bonus, offering travellers a discount of up to $1356 per couple on their 2014 holiday if booked before December 20, 2013. See: rockymountaineer.com
WHEN TO GO: The Rocky Mountaineer runs from late April to early October.
The writer was a guest of Rocky Mountaineer, Canadian Tourism Commission, Destination British Columbia and Travel Alberta.


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Good morning – Friday dance! :lol:
This has perhaps been the fastest week of my life. I swear I blinked on Monday and, when I opened my eyes, it was Friday. Weeks where you're trying to get your life back together always seem to go like that. No? Either way – awesome!
This morning I whipped up one of my favorite breakfasts, which I've been missing on hard for the past couple of weeks – Oatgurt!
- 1/3 cup each old fashioned oats, unsweetened vanilla almond breeze and water
- 1 banana (1/2 sliced in while cooking, 1/2 on top)
- cinnamon, vanilla extract
- Raspberry Chobani Greek Yogurt
- Kashi GoLean Crunch
Directions: Microwave oats, milk, water and 1/2 a banana for 2 minutes. Stir, then nuke for 1.5 more minutes. Add in cinnamon & vanilla then top with cold Greek yogurt and crunchy Kashi cereal.
The combo sounds weird, right? Hot oats and cold yogurt? It works. Try it! :D
In other news, I thought I'd tack another city onto the tour de IGE and head to Chicago for the weekend!
One of my best girlfriends, who lives in the city, recently had a little girl and we're throwing her a baby shower tomorrow! Squeal – I can't wait to hold and fawn over her! :D
At any rate, I'm taking a half day of work and driving up this afternoon, so I'm grabbing lunch on the road. I'm stopping at a local deli to pick up some goodies for the party before I go, so I might just grab something there, me thinks. :D
So You Want To Plan a Trip…
I've received a ton of questions this week about how Ben and I planned our trip to Italy. Planning a trip overseas can be overwhelming. Where do you stay? How do you know what to do when you get there? What about the language barrier? Here are my Top 10 tips for planning a trip overseas.
1. Determine your budget.
Determine how much you're willing and able to spend on your trip. Remember to factor in the amount of money you'll need for food, sightseeing, getting around, shopping etc. once you arrive.
2. Decide where you want to go.
Will your destination be a tropical island, or a snowy getaway? Are you interested in sight seeing or relaxing? This will also determine how much money you're going to need to have on hand once you arrive. Ie laying on the beach isn't as expensive as buying a mountain pass to ski all day.
3. Decide when you want to go.
Heading to Australia during your summer break may seem like a good idea, but it's actually winter down under when it's summer in the US. Make sure you're aware of what the weather conditions are going to be like at your destination before you book your trip.
4. Figure out how you're going to get there.
If you're able to drive to your destination, and only need to book a hotel, I recommend Hotels.com. Thier website has a great structure for comparing prices, ratings and areas.
If you need both a flight and hotel, my go-to booking agent is Expedia.com. Expedia always has the lowest prices of any of the travel websites, and they have the wonderful option of booking a multi-city trip. For example, I was able to book a flight and hotel in Rome, then a hotel in Praiano and return via the Naples airport, which was closer to Praiano then Rome.
Whether I'm flying or driving to my destination, I always check out TripAdvisor.com to double check the hotels I'm thinking about booking. Simply search for the hotel you've found on Hotels.com or Expedia:
Then check out the reviews:
I've never been steered wrong by this website. Of course, you're going to get the occasional bad seed who bashes the hotel just because they're the type of person who can't be pleased in life, but generally you can get a really good feel as to if it's going to be a good choice or not.
5. Research things to do.
If you're going to Bora Bora, your list of things to do may be as simple as lay on the beach. If you're planning on going to a large city with lots to do, make sure to do some research. I love reading travel blogs like YoungsAroundTheWorld.com or checking out guidebooks at the local library to get ideas. Googling "Top 10 Things to Do in XYZ" always turns up some great ideas as well.
6. Look into transportation methods available at your destination.
Will you be traveling to multiple cities during your trip? A call to your hotel might help you determine how to get from point A to point B, but a quick search on the Internet will most likely answer your questions too.
When trying to figure out how we were going to get from Rome to Praiano, I simply Googled, "how to get from Rome to Praiano" and the answer popped right up.
My encouraging statement is – it's often easier than you think!
7. If you're planning on traveling Internationally, and need a passport, allow at least 3-4 months to acquire one.
Getting a passport takes a long time these days and, if you're recently married, allow the same amount of time to get your current passport updated. I completely failed in that department, as my still valid passport still had my old last name on it, so I took along a certified copy of my marriage license, which worked too!
8. Exchange money before you go.
You'll often get better exchange rates if you go through your bank to get the local currency instead of waiting until you're at the airport. Make sure to do this at least a week in advance of your trip as most banks will have to order the currency. Often times they don't keep a ton of it on hand!
9. Brush up on the local lingo.
Don't assume everyone speaks your language. When I lived in Japan for a summer in college, nearly all the locals I interacted with knew enough English to get by. That wasn't really the case in Italy. Having a pocket translator book and knowing a few key phrases helped immensely!
10. Notify your bank, family and friends before you leave.
Make sure someone will know where you will be at all times of your trip. Hand out copies of your itinerary to anybody who will take one and let your bank know that you're leaving the country, if you plan on using your credit card, so they don't suspend your account for suspicious activity.
All in all, traveling overseas is one of the most rewarding things you can ever do in your life. At times, the thought of planning and actually DOING it may seem daunting, but you'll thank yourself a million times over in the end. You only live once, see the world while you're at it!
Have a good day!
What's your best tip for traveling overseas?


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Hometown: Portland, Indiana Undergraduate Institution: Indiana University, Bloomington, Indiana From a young age I cultivated an interest in science, but in my hometown of rural Indiana there were few examples available to point me toward academic research. As a junior in high school I attended a weekend seminar for students interested in research, where I met someone who was pursuing an MD/PhD in a dual degree program. I fell in love with the physician-scientist pathway and never looked back!
Though I enjoyed my collegiate research experiences, I was looking for something more translational, and over and over again I was pointed toward Cincinnati Children's. I attended a number of research presentations during my first two years of medical school, and the most exciting projects seemed to be in the labs of Molecular and Developmental Biology faculty. Members of the MDB program, from faculty to other students, have done a wonderful job of creating an atmosphere of willingness to teach and openness to questions. I have appreciated this atmosphere often as I learn new methods and techniques. I am continually impressed at the commitment of MDB faculty to improving not only the state of knowledge in their field but the lives of patients at Cincinnati Children's and people in the Cincinnati community.
My project in the Muglia Lab gives me the opportunity to work directly on human disease processes while also studying them in other model organisms. This project focuses on corticotropin-releasing hormone (CRH), a placental hormone associated with birth timing. My research interest is the evolution and regulation of CRH expression by endogenous retroviral elements.
3333 Burnet Avenue, Cincinnati, Ohio 45229-3026
New to Cincinnati Children's or live outside of the Tristate area? 1-877-881-8479
© 1999-2017 Cincinnati Children's Hospital Medical Center. All rights reserved.


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It only takes a minute to get started. Fill out our uncomplicated sign up form and login to the website.
This step is elective but will dramatically boost your chances of getting noticed by other people on the site. Write about yourself, your interests and atach your nicest photo of yourself.
Use our website's state-of-the-art search to spot members who satisfy your needs. Or just flip through listings and spot daters that interest you.
Found someone who interests you? Send them a few words or just a wink and see what develops from there. With a little luck you'll be on your way to discovering your proper partner.
It's really quick


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Calle 13 is back with new hard-hitting, politically-conscious verses powerful enough to start a revolution.
The Puerto Rican duo joined forces with Nuyorican band, Outernational, for their new track also featuring Tom Morello and Chad Smith, "Todos Somos Ilegales" ("We Are All Illegals"). The track brings to light the social injustices affecting the immigrant community and challenges the existence of the term "illegal" to define human beings in the U.S.
The new song is part of Outernational's 18-track album properly titled, Todos Somos Illegales. Watch the video below to check out Residente's on-point delivery.
What do you think about the track?


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Moscow (Sep. 7)
The Agrojoint, the instrument of the Joint Distribution Committee of America in the Jewish colonisation work in Russia, is in addition to its agricultural settlement work engaging also in a large-scale activity aiming at the industrialisation of the Jewish masses in the Soviet countries. Scores of Jewish co-operatives have been equipped by the Agrojoint in the past few years with machinery, tools and in some cases raw material. During last year, the Agrojoint subsidised with both money and machinery artisan industrial enterprises conducted by the relief societies in 58 towns and townships in the Ukraine, to the value of over 1½ million roubles (516,366), besides 22 Jewish co-operatives in Moscow, three in Leningrad and one in Simferopol, to the value of 363,813 roubles; making a total of nearly 900,000 roubles (880,813).
Up to January 1st., 1930, the Agrojoint subsidised 235 artisan industrial enterprises, with 6,330 workers; up to January 1st., 1931 it subsidised 336, with 18,476 workers, meaning that the number of such enterprises subsidised by the Agrojoint has increased in the course of the year by over 100, and the number of workers has been trebled.
The Agrojoint is now completing a big knitted-goods factory for 600 workers in Eupatoria, in the Crimea. The Crimean Government has given the old prison building to be used for the purpose of the factory, and the Agrojoint has rebuilt it so that it should be fitted for the functions of a factory. The cells have been transformed into factory floors, and a new storey has been added. A large restaurant has also been installed, where communal meals will be supplied to the workers, and dwelling places will also be built for the workers. The factory is equipped with the latest model machinery, brought over by the Agrojoint from abroad. The Agrojoint has called in foreign experts to instal the machinery and to teach the workers how to work them.
The factory will employ Jewish workers exclusively, mostly Jewish women from the small townships, where they have no prospect of earning a livelihood. When the factory is completed, it will be handed over to the local co-operative, which pledges itself by an agreement with the Agrojoint to keep it supplied with raw material and working capital. By the same agreement, the co-operative has pledged itself to employ only Jewish workers in this factory, and if this clause in the agreement is not conformed with, the Agrojoint has the right to remove from the factory the entire equipment, and to establish a factory of its own.
It is understood that the factory will be ready for work in December. It will be the largest knitted-goods factory in the Crimea, and is expected to play an important part in the industrialisation of the declassed Jewish population of the small towns.


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NISHINOMIYA, HYOGO PREF. – Double-duty right-hander Shohei Otani lit up Koshien Stadium on Tuesday night, striking out 11 in eight innings as the Hokkaido Nippon Ham Fighters blanked the Hanshin Tigers 4-0 in interleague action.
Otani (6-1), who often plays right field for the Fighters on days when he isn't pitching, hit 160 kph twice and another former high school sensation, outfielder Sho Nakata, homered and drove in two runs at Japan's Mecca of high school ball in Hyogo Prefecture.
"My memories here (at Koshien) had not been good ones, but I managed to make a good one," he said.
The only blemish on Otani's evening was Yamato Maeda's two-out single in the sixth inning. Maeda, however, was caught stealing to end the inning, allowing Otani to leave the mound having faced the minimum of 24 batters over eight innings.
The 11 strikeouts, in a game that was held up 22 minutes for rain, are a career high for Otani, who will turn 20 on July 5.
He left the mound briefly to seek treatment with a 1-1 count on the last batter in the eighth. Otani, who left his last start due to cramping in his right calf, returned to the to get the final out, but did not come back out in the ninth.
"I want to do whatever it takes to finish out games," he said. "My condition was not that great tonight, but I was able to hang in there."
Carp 6, Eagles 1
At Hiroshima's Mazda Stadium, Yusuke Nomura (4-3) allowed a run in seven innings to win for the first time since April 22 and was backed by Brad Eldred's 22nd home run and Rainel Rosario's sixth in Hiroshima's win over Tohoku Rakuten.
Dragons 6, Lions 1
At Nagoya Dome, Yudai Ono (4-3) changed speeds effectively to go the distance for the first time this season as Chunichi whipped Seibu. Yohei Oshima went 3-for-5 and singled home the Dragons' first two runs.
BayStars 11, Marines 6
At Yokohama Stadium, Shoichi Ino (8-3) moved into a tie for the league lead in wins in a 140-pitch complete game effort as Yokohama defeated Chiba Lotte.
Buffaloes 6, Giants 5


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Many of you have been getting very excited about the chance to play Resistance 3's competitive multiplayer modes online when the Resistance 3 Public Beta launches. Today, we're happy to give some additional info about the launch dates for the beta.
For those of you who have received Early Access to the Public Beta via specially marked packages of SOCOM 4, we will be opening the beta to you at some point on Thursday, August 4th. Your existing codes will be able to be redeemed via the PlayStation Store and the Redeem Code button. PlayStation Plus subscribers in the U.S. will also be invited to join the beta beginning on August 23rd. If you're a subscriber, all you'll have to do is navigate to the PlayStation Plus section of the PlayStation Store to download the beta.
The first thing that comes to mind when most people think of Ratchet & Clank (aside from Qwark's dashing good-looks and unflappable courage) is the incredible arsenal of weaponry. The Insomniac Games team has always prided themselves on delivering out-of-this-world weaponry that gives you all kinds of wacky ways to turn your enemies into space dust. In honor of that long lineage of weaponry, we're kicking off our gameplay video series with four videos highlighting the weapons you'll find in Ratchet & Clank: All 4 One.
July just flew by with amazing deals on movies and television shows. And this week we've got even more to top it all off!
This week, New Releases b rings the intense drama Trust, starring Clive Owen (Children of Men), Catherine Keener (The 40-Year Old Virgin), Viola Davis (Knight & Day) and Noah Emmerich (Super 8). Owen's daughter falls victim to a cyber-predator and he becomes determined to track down the man responsible for her suffering.
Limitless, Take Me Home Tonight and Dylan Dog: Dead of the Night have climbed the movies charts in Top Downloads. Over in top TV, you'll find all the episodes of season 5 of Showtime's hit series Dexter where you can get geared up for the new season of slicing and dicing coming later this year.
Annihilation — the third pack of DLC maps for Call of Duty: Black Ops – comes to the PlayStation 3 late tonight after 2am Pacific Time. The DLC offers four new multiplayer arenas and a new jungle-based Zombies survival experience in Shangri-Li. In celebration of the big release, developer Treyarch has deemed that the double XP will flow all weekend long. I'll be hosting a gameplay session this Friday night to soak some of that up myself, and my favorite game type is Domination. Truth be told, I'm not that good a shot, so objective-based modes like this one let me help the team and keep leveing up even if I'm nowhere near the top of the K/D ratios.
A public service announcement from Lockwood Publishing: Sodium 2 has seen its 3 millionth race! This means that Sodium 2 players have collectively traveled more than 75% of the way from the Earth to the Sun. In recognition of this amazing achievement, Lockwood Publishing is unlocking new Reverse Mode tracks in Sodium 2 this week. Head to the Sodium 2 launch grid on Thursday, July 28th to tear it up on your new tracks!
You may have seen the teaser posters placed throughout PlayStation Home that show a variety of mech silhouettes. This Thursday, these incredibly awesome MechJet costumes will finally be available from the Sodium store in the PlayStation Home Mall. These are seriously some of the most impressive costumes to ever be released in PlayStation Home. Watch this trailer and then tell us what you think in the comments section.
Formally announced at PlayStation's E3 2011 press conference, the upcoming PlayStation Move Pack for LittleBigPlanet 2 will greatly expand the game's already prodigious creation suite and add countless new gameplay variants. Based on my hands-on time, PlayStation Move support radically evolves the gameplay possibilities of LittleBigPlanet 2, whether it's flinging and manipulating objects using the new Brain Crane power-up, creating outlandish Move-focused minigames from scratch, or animating characters and props by recording your PlayStation Move gestures.
"It's the biggest update we've ever done," Media Molecule's Level Design Lead Kengo Kurimoto told me during a guided tour of the update last week in New York City.
Hey, PlayStation Bloggers! I wanted to share this highlight reel from the panel Jenova Chen and myself were on last week at Comic-Con (it was the first time attending for both of us!). We had a great time interacting with new and old fans, as we also had a playable demo in the main exhibit hall at the Sony PlayStation booth. We gave away a bunch of Journey t-shirts as well, so if you are one of those people, please show us a photo of you wearing it on our Facebook page – we love when our players represent! And if you weren't able to get a shirt at the show, follow us on Facebook for more chances to win one.
Check out the HUGE THQ 50% sale on select games & add-ons – notable sale items include: Costume Quest & Grubbins on Ice, Stacking & The Lost Hobo King, Red Faction: Guerrilla Game and add-ons, Red Faction: Battlegrounds Game and add-ons, & You Don't Know Jack add-ons.
On the new releases front, there are (4) PS3 games out today Back to the Future: The Game – Episode 5, Deadliest Warrior: Legends, Golden Axe, Section 8: Prejudice – Special Offer Bundle and Add-on. Speaking of special bundles, for those of you that have yet to experience the greatness of Fat Princess, there is a limited time Fat Princess Anniversary Bundle that includes the PS3 game, Fat Roles DLC, brand new dynamic theme and the Fat Princess avatars. Download today!!
Would you be willing to answer a few brief questions about PlayStation.Blog?


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Evangelicals pushing immigration reform in new Florida radio ad
An Evangelical group is trying to round up support for immigration reform with a radio ad on Christian radio in Florida. The ad, part of a multi-state push by the Evangelical Immigration Table, features the voice of David Uth, senior pastor of First Baptist Orlando.
In a conference call this afternoon, Uth said there is a consistent message in scripture to "welcome and treat fairly all people but especially the stranger and foreigner."
The other states are Colorado, North Carolina, and Texas. The ads follow an initial effort in South Carolina, a hotbed for the immigration debate.
"The ad campaign further increases the Evangelical Immigration Table's pressure on Congress to produce a new, bipartisan immigration process this spring," according to a release. "It also presages the April 17 Day of Prayer and Action in Washington, during which evangelicals will meet with legislators to demand action, as well as continue the biblically inspired reflection on immigration exemplified by the 'I Was a Stranger' immigration prayer challenge."
The Florida push comes as Sen. Marco Rubio over the weekend expressed concern about moving to quickly on an immigration bill he has been working on with seven other senators.
The ads began today and will run through the middle of April.


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Intel Xeon E5-2667 - 2.9 GHz - 6-core - 12 threads - 15 MB cache - LGA2011 Socket - OEM - for Compute Module HNS2600; Server Board S2600; Server System P4308, (CM8062100854802)Item#: 9067486 | Model#: CM8062100854802
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Duane Arthur Portwood of Sheridan, Wyoming passed away peacefully and surrounded by loved ones on Saturday, May 19, 2012 at the V. A. Medical Center.
Born in Four Corners, Wyoming, August 26, 1934 to Earl and Lillian Portwood, Duane grew up on a ranch near Newcastle, Wyoming and loved caring for farm animals, growing gardens and harvesting crops. He expanded those interests in his studies and received a Bachelor of Science with Honors in Agriculture from the University of Wyoming in 1958 and later earned his Masters of Science in Agricultural Economics from the University of Wyoming in 1965.
Duane served in the United States Army and the Wyoming Army National Guard from 1958 to 1962 as a Radio TeleType Operator. He achieved the rank of Specialist/E4.
Duane enjoyed passing on his love and knowledge of agriculture to others and was an Instructor in Agriculture and Business at Eastern Wyoming College in Torrington, Wyoming where he earned recognition as one of the "Outstanding Educators of America." After 8 years as an Instructor, he moved back to Sheridan, Wyoming and started a public accounting practice. In 1978, Duane began his career as a rural electric cooperative manager and retired in 2000 as the General Manager of Sheridan-Johnson REA, a post he had held for 9 years.
In retirement, Duane remained active in his passion for ranching through his ownership and operation of DuCon Cattle Enterprises, a registered Polled Hereford operation. He also developed new interests and began writing cowboy poetry and short stories. In November 2007, he published a book of his poetry entitled "Bunkhouse Ramblings: Poetry and Prose". One review of the book stated the following, "Pure delight! Bunkhouse Ramblings will bring the beauty and fresh air of the wide open ranges of Wyoming right into your heart. The author vividly describes his love of the outdoors and ranch life through his poetry. Memories will be stirred of the days when life was easier. Poetry that is fresh and clean will bring enjoyment to all ages." In addition, Duane had over 4 dozen short stories published in The Sheridan Press in the "Center Stage" section.
In retirement, Duane also enjoyed volunteering at the Sheridan Senior Center where he helped edit the Volunteer Newsletter, manned the dining room desk, shared his cowboy poetry and short stories and participated in many other senior activities.
Duane was a student, a military veteran, an educator, a business man, a rancher, a poet and a writer but most importantly he was a loving husband, father and grandfather and a man who lived his life with grace, humility and integrity. He was loved by many and will be missed by all.
Duane is survived by his wife, Constance, his sons, Duane Andrew and Brent, his step-daughters, Maria and Yolanda, his step-son, Armando, his sisters, Letha and Sylvia, his brother, George and his 12 grandchildren, Diane, Sarah, and Molly Portwood, Brandon and Elizabeth Portwood, Ravin and Dan Alexander, Sean and Amanda Kelly, and Heather, Ashley and Austin Brennan.
Duane was laid to rest in the Masonic Oblong Square at the Sheridan Municipal Cemetery in a private ceremony. In lieu of flowers and other offerings, donations can be made to the Sheridan Senior Center.
Kane Funeral Home have been entrusted with the arrangements.
Online condolences may be written at www.kanefuneral.com.


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Precious metals could lose some steam in the near term, but they are "bound to rebound" and have raised their price forecasts over the longer term, according to HSBC.
The global research team has lifted its price forecasts for gold, silver and the platinum group of metals on the belief that the bull markets remain "essentially intact".
HSBC's gold price forecast for 2012 was lifted to $US1500 an ounce from $US1300 an ounce, while its long-term, five-year forecast is now $US1250 an ounce, up from $US1050 an ounce. Its 2013 forecast is $US1450 an ounce.
Gold was fetching about $US1522 in Asian trading yesterday. on Wednesday.
The bank believes gold prices will hinge on the monetary policy of global central banks, inflation expectations, commodity prices, evolving sovereign debt issues in Europe, geopolitical risks and concerns about US debt levels
Analyst James Steel said unease about monetary and fiscal policies should rekindle gold's rally, despite a modest rise in supply.
For silver, he believes strong industrial demand and a recovery in investor appetite should offset scrap and mine supply growth.
"Investors have favoured silver and coin sales, but prices appear high, especially relative to gold."
HSBC's price forecast for the white metal is $US29 an ounce in 2012 and $US20 an ounce on a five-year outlook, up from $US20 and $US15 respectively.
"Although silver is priced closer to its equilibrium value, its near-term bias is upward in our view."
Referring to silver, Macquarie analyst Hayden Atkins has examined when to catch the falling knife.
Mr Atkins said Chinese demand has not driven the huge price volatility over the past month. He said the narrowing premium between the LBMA and the China price would be a welcome development in a falling market, in that it could induce interest out of China. However, the two prices are not quite correlated.
Macquarie remains cautious on the metal's outlook and is yet to find a compelling reason to believe silver is out of the woods.
Mr Steel said that for PGMs, widespread belief that Russian stockpiles are near exhaustion has supported palladium prices.
The global bank forecasts a 2012 palladium price of $US750 an ounce and a five-year price of $US700 an ounce. For platinum, it is $US1750 an ounce and $US1625 an ounce respectively. HSBC also introduced a forecast of $US1650 for 2013.
Separately, Merrill Lynch notes that Japanese reactor capacity factors will bounce back in 2012 and forecasts a rebound in the uranium price.
"We view that spot uranium has bottomed and will strengthen from current levels," analyst Glen Chipman said.
Merrill Lynch maintains its 2011 spot price forecast of $US66 a pound. Globally, its preferred exposure comes from Australian-listed
The Australian Financial Review


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Make yourself at home in one of the 45 air-conditioned guestrooms. Complimentary wired and wireless Internet access keeps you connected, and cable programming provides entertainment. Conveniences include desks, and cribs/infant beds can be requested.
Take advantage of recreation opportunities such as an outdoor pool or take in the view from a terrace and a garden. Additional features at this hotel include complimentary wireless Internet access, concierge services, and a picnic area.
Enjoy a satisfying meal at a restaurant serving guests of Cap Saint Louis. Quench your thirst with your favorite drink at a bar/lounge. A complimentary continental breakfast is served daily.
Business, Other Amenities
Featured amenities include a business center, luggage storage, and a safe deposit box at the front desk. Guests may use a roundtrip airport shuttle for a surcharge, and free valet parking is available onsite.


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Successful brands or key to any company's success
"Some consumers would walk a mile just to find Camel cigarettes and would wait in line for hours to buy a Swatch. Others are attached to their cars or motorcycles, while teenagers spend hours and hours talking about hip clothing brands" (Schroeder & Salzer-Morling, 2006). The subsequent question is: are these people victims of manipulation, publicity or are they simply people who love symbols? Chevalier and Mazzalovo (2004) claim that a brand does not represent manipulation, that consumers choose certain brands as they see them as the best on the market.
If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
Volume (Year): 12 (2009)
Issue (Month): 1 Special (July)
Pages: 174-179
|Contact details of provider:
| Postal: 6 ROMANA PLACE, 70167 - BUCHAREST
Phone: 0040-01-2112650
Fax: 0040-01-3129549
Web page: http://www.management.ase.ro/
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AMSTERDAM – Three US internationals pitched in with strong Champions League performances on Wednesday, headlined by Schalke midfielder Jermaine Jones setting up the 1-0 winner against Olympiakos that clinched their place in the knockout round with a game to spare.
With 13 minutes to play, the No. 13 shirt won a challenge to square the ball to Christian Fuchs, whose low liner tucked inside the far post on one bounce from nearly 30 yards. The Miners will now try to win Group B with a victory at Montpellier on Dec. 4.
READ: Parkhurst's Nordsjælland eliminated in contentious affair
Elsewhere, Oguchi Onyewu was largely in control of his zone, but already-advanced Málaga let a two-goal lead slip in their 2-2 draw with Group C hosts Zenit St. Petersburg.
Though he spent most of the night manhandling star forward Hulk, the US defender played an unfortunate part in the Russians' late equalizer. Four minutes from time, Onyewu hustled to clear a shot off his line, only to have the ball fall to where Viktor Faizulin could thread a shot through the area crowd from 16 yards.
Meanwhile, Sacha Kljestan was arguably the most effective midfield player in 10-man Anderlecht's 3-1 defeat to visiting AC Milan.
The Mauves traffic director led all players in distance covered on the night, providing a small array of timely tackles and dangerous attack work. The loss leaves Anderlecht trailing third-place Zenit for the Europa League parachute by goal differential ahead of their closing-day trip to Málaga.


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I'm having problems with IE 11 on two laptops, one is a fairly new Win 8 machine, the other Win 7. Just a default installations no fancy gimmicks or customizing.
For 3 months or so IE10 worked perfectly on the Win 8 machine, then an automatic update installed IE 11. Soon after that I started getting a pop-up, "Internet Explorer has stopped working" & "Checking for a solution". There never was a solution, but restarting IE usually cleared the problem, until next time, which might have been a day or two later. Now things have reached a point where IE 11 starts normally with Google as the home page, and there will be no error messages until something, anything, is entered in the search box. Within a second or two there's an error message:
"Internet Explorer has stopped working" & "Checking for a solution".
Followed shortly by:
"A problem caused the program to stop working correctly. Windows will close the program and notify you if a solution is available."
I'd download Firefox but IE shuts down, that's one way to keep the opposition at bay.
I tried System Restore, the earliest restore point is just one month ago. Ran that, and it ended with "System Restore Failed." And I think it was "C:\Windows not restored" or words to that effect. I've undone the restore, but could try it again if the exact wording would help.
The Win 8 machine is also using IE 11, again a plain vanilla installation, but this one only pops up the error message on some Web pages, others cause no problems at all.
Where to start looking????


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By Jennifer L. Saunders, CIPP
Week in and week out, media stories call attention to the latest and greatest data breaches-and with seemingly increasing frequency, those headlines are followed by announcements of U.S. Federal Trade Commission (FTC) investigations or enforcements as well as class-action lawsuits.
In what privacy professionals are describing as a growing tide of such actions, businesses, organizations and marketers are being cautioned to take preemptive steps to avoid becoming targets.
That was the message shared by D. Reed Freeman Jr., CIPP, of Morrison & Foerster, and Jim Halpert of DLA Piper in a session they led at the IAPP Privacy Academy in Dallas, TX, in September.
In what he described as the "second great tidal wave of class-action lawsuits," Freeman highlighted recent actions and FTC investigations spurred by privacy concerns about forms of online tracking more sophisticated than the earlier uses of cookies and Web beacons that prompted suits in the past. History sniffing, persistent online tracking, location tracking, deep packet inspection and changing privacy policies and practices--essentially, employing any technical option to "undermine user choice"--can put the spotlight on companies, he noted.
"Class actions are a high-profile privacy risk," Halpert added, and can not only be costly to defend but also hurt your brand. When doing risk management, he stressed, it is important to pay close attention to the details.
And, Freeman added, many companies caught up in recent headline-making privacy lawsuits "had no idea at all of the technology being used by the vendors, but that didn't matter at all when it came to these class actions."
Freeman and Halpert offered businesses particular insight into the emerging trend where "bad press" appears to lead to FTC investigations and class actions, using the example of the ongoing installments of the "What They Know" series in The Wall Street Journal and investigations that emerge on the heels of widely publicized breaches, tracking or targeting activities.
What can a company or marketer do to avoid that negative publicity, those costly legal bills or an FTC action? First, the experts pointed to what not to do, including failing to honor privacy representations, providing inadequate security or engaging in targeted advertising or tracking practices that fall outside the mainstream.
To help avoid lawsuits and enforcement actions, the presenters recommended key considerations--including choosing your partners wisely; creating effective contracts and monitoring them; being wary about new online features to avoid "first-mover risk;" providing notice and affirmative consent opportunities before changed policies take effect; evaluating all major changes against your privacy policy; staying current on legal and businesses changes, and building privacy into products from the start.
Without such use of privacy by design, Halpert noted, businesses run the risk of those "nasty surprises" that can lead to FTC and court actions.
"If a consumer makes a choice about their data, respect it," Halpert said, adding that, for any uses that would be material to privacy-sensitive consumers, it is important to be clear and upfront about what data you collect and why.
Freeman added that after 15 years of FTC involvement, the touchstone on privacy remains consumer surprise or the "creepy" factor.
Another presenter at the Privacy Academy shared a similar perspective.
As Anne Toth, head of privacy at Yahoo, noted, "When a consumer expects one thing and you give them something different, that's when trust is eroded."
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Polo Black Eau de Toilette Spray by Ralph Lauren
Ralph LaurenBuy Now
Launched by the design house of Ralph Lauren in 2005, Polo Black is contemporary, bold and audacious fragrance. It opens with exciting top notes of iced mango, green effervescent accord and Spanish sage, then gently transcending to middle notes of hedione, silver armoise and lush liquid accord and finishes with bottom notes of Tonka bean, timberol, sandalwood and patchouli noir. Make your occasion special with Polo Black.


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|Sport, 1 pitch, 80'
|YDS: 5.13a French: 7c+ Ewbanks: 29 UIAA: IX+ ZA: 29 British: E6 6c [details]
|Rob Robinson
|Page Views:
|Submitted By:
|yevquest on Feb 1, 2009
|Comments on Abortion Contortion
|Add Comment
|Show which comments —
By Blake Cash
From: Chattanooga, TN
Dec 15, 2010
rating: 5.13a 7c+ 29 IX+ 29 E6 6c
|Much better route than the 2 stars that it's given here. Great mid 5.12 climbing to a great 5 move crux on amazing rock. The pebbly rock is for only 2 moves or so. Some of the coolest movement of all the t-wall sport routes...as it isn't the simple tiered roof tugging that the rest have.


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Interiores II
Previously unpublished poem. Handmade books published by Ediciones Vigía under the auspices of the Cuban Ministry of Culture. Poem in manuscript reproduced on single leaf of coarse brown paper, with ragged edges, folded to 25 x 9 cm (opens to 25 x 25 cm). Poem is preceded by two illustrated leaves, the second incorporating a piece of wood with evidence of termite activity. Heavy cardstock wrappers are trimmed to the shape of an upright section of tree trunk or log, illustrated to depict rough texture of bark and exposed cross-section at top, and bound to leaves of text and illustrations by three pieces of heavy brown yarn threaded through three holes at left margin and tied. On right side, front and back wrappers are trimmed to depict two small protruding branches that have been cut; from upper one is tied a length of light-weight brown yarn to which is tied a small wooden tag bearing the copy number. Place of publication and publisher from colophon. Consta de cientocincuenta ejemplares ... --Colophon. MSU has copy no. 16. MSU copy: gift of Jeanne Drewes (2000).
- Alonso, Digdora, 1921-
- Estévez Jordán, Rolando, 1950-
Publication Date: 2000
Original Size: [6] p. : ill. ; 29 cm.
Collection: MSU Libraries Cuban Artists' Book Collection
Call Number: oversize N7433.35.C8 C8 Box 5, Tray 5C
© 2017 Michigan State University Board of Trustees. MSU is an affirmative-action, equal-opportunity employer.


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Effects of Antidiabetic Medications on the Postprandial State in Prediabetes
This study has been completed.
The University of Texas Health Science Center, Houston
The Center for Clinical and Translational Sciences (CCTS) Clinical Research Unit at The University of Texas Health Science Center at Houston
Information provided by (Responsible Party):
Absalon D Gutierrez, The University of Texas Health Science Center, Houston
ClinicalTrials.gov Identifier:
First received: April 1, 2014
Last updated: May 4, 2017
Last verified: May 2017
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
This project addresses cardiovascular disease risk in patients with prediabetes. Levels of lipids after eating a meal ("postprandial lipids") are strong independent predictors of cardiovascular risk. Newer anti-diabetic agents - exenatide and saxagliptin - impact lipid metabolism. These medications will be studied for their effect in reducing both postprandial lipid levels and arterial dysfunction.
|Prediabetes Obesity
|Drug: Exenatide Drug: Saxagliptin Drug: Exenatide ER Other: Placebo
|Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Masking Description:
Placebo pills and placebo injections providedPrimary Purpose: Treatment
|Official Title:
|Comparative Effects of Antidiabetic Medications on Postprandial Hyperlipidemia, Free Fatty Acid Signaling, and Endothelial Dysfunction in Individuals With Prediabetes
Resource links provided by NLM:
MedlinePlus related topics: Prediabetes
Drug Information available for: Exenatide SaxagliptinU.S. FDA Resources
Further study details as provided by Absalon D Gutierrez, The University of Texas Health Science Center, Houston:
Primary Outcome Measures:
- Monocyte NfkB [ Time Frame: 2 hours after ingestion of meal ]Monocyte NfkB
Secondary Outcome Measures:
- Triglycerides [ Time Frame: 6 hours after ingestion of meal ]triglycerides
Other Outcome Measures:
- Forearm blood flow [ Time Frame: 6 hours after meal ]Forearm blood flow via strain gauge venous occlusion plethysmography
- Free Fatty Acids [ Time Frame: 6 hours after meal ]Free Fatty Acids
|Study Start Date:
|March 2014
|Study Completion Date:
|March 2017
|Primary Completion Date:
|March 2017 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Saxagliptin
Saxagliptin 5 mg orally
Drug: Saxagliptin
Single dose orally (5 mg)
Other Name: Onglyza
Experimental: Exenatide ER
Exenatide ER 2mg subcutaneously
Drug: Exenatide ER
Subcutaneous injection (2mg) weekly for 6 weeks
Other Name: Bydureon
Placebo Comparator: Placebo
Other: Placebo
Placebo tablets and Placebo (normal saline) injections
Experimental: Exenatide
Exenatide 10 mcg subcutaneously
Drug: Exenatide
Single subcutaneous injection (10 mcg)
Other Name: Byetta
Detailed Description:
It is a paradox that medical efforts to control blood glucose in type 2 diabetes mellitus have not decreased the risk of cardiovascular disease. Postprandial lipid concentrations are a strong predictor of cardiovascular risk, independent of traditional cardiovascular risk factors. The new classes of antidiabetic medications - GLP-1 agonists and DPP-IV inhibitors - affect lipid as well as glucose metabolism. This study will investigate the efficacy of these medications in reducing postprandial hyperlipidemia, disrupting the concurrent proinflammatory free fatty acid signaling, and ameliorating endothelial dysfunction in individuals with prediabetes. This will consist of a single center, randomized, crossover, placebo-controlled double-blinded prospective trial involving three study arms representing the aforementioned medications: exenatide (GLP-1 agonist), saxagliptin (DPP-IV inhibitor), and placebo (control arm). For each study arm, subjects will eat a standardized atherogenic high-fat test lunch. Venous blood draws and measurements of forearm blood flow will be done prior to the meal and periodically during a 6-hour period after the meal. Forearm blood flow measurements will assess for changes in endothelial function. The blood will be analyzed for multiple markers of hyperlipidemia and free fatty acid signaling. After completing the three randomized study visits, subjects are invited to participate in an optional, nonrandomized extension study. For the extension study, subjects will take exenatide ER (extended-release exenatide) weekly for total of six weeks. Then subjects return to eat a standardized atherogenic high-fat test lunch. Venous blood draws and measurements of forearm blood flow will be done prior to the meal and periodically during a 4-hour period after the meal, for the same analyses described before. The results will provide new insights into the anti-inflammatory effects of multiple antidiabetic medications via the mechanisms of postprandial hyperlipidemia, free fatty acid signaling, and endothelial function in prediabetic individuals.
|Ages Eligible for Study:
|30 Years to 70 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Men and women, ages 30 to 70 years of age inclusive
- Diagnosis of Prediabetes - defined as either impaired fasting glucose (fasting glucose of 100-125 mg/dL), impaired glucose tolerance (2-hour postprandial blood glucose of 140-199 mg/dL after 75 gram oral glucose challenge), and/or a hemoglobin A1C ranging from 5.7% to 6.4%
- Subjects are allowed, but not required, to be on statins, ACE-inhibitors, beta-blockers, angiotensin-receptor blockers, thiazide diuretics, and/or loop diuretics at doses that have been stable for at least the last 3 months
- BMI between 30-35 kg/m2 (±1 kg/m2)
- Body weight has been stable (±4-5 pounds) over the prior three months.
- Women of childbearing age must agree to use an acceptable method of pregnancy prevention (barrier methods, abstinence, or surgical sterilization) for the duration of the study
- Patients must have the following laboratory values: Hematocrit ≥ 34 vol% S. creatinine < 1.5 mg/dl in men and 1.4 mg/dl in women AST (SGOT) < 2.5 times ULN, ALT (SGPT) < 2.5 times ULN, alkaline phosphatase< 2.5 times ULN
Exclusion Criteria:
- History of Type 1 or Type 2 diabetes mellitus
- History of diabetic ketoacidosis or hyperosmolar nonketotic coma
- Pregnant or breastfeeding women
- Patients must not be receiving lipid-lowering medications other than statins within the last 3 months
- Patient must not be receiving metformin, DPP-IV inhibitors, GLP-1 agonists, thiazolidinediones, insulin, sulfonylureas, acarbose, SGLT-2 inhibitors, corticosteroids, or immunosuppressive therapy within the last 3 months and cannot take them for the duration of the study. Patient must not be receiving NSAIDS or antioxidant vitamins within the last 1 week, and cannot take them for the duration of the study.
- Patients must not be on hormone replacement therapy.
- Patients with diabetic gastroparesis
- Patients with current tobacco use
- Patients with active malignancy
- Patients with history of urinary bladder cancer
- Patients with dietary restrictions precluding a high-fat meal
- Patients with a history of clinically significant heart disease (NYHA III or IV; more than non- specific ST-T wave changes on the EKG), peripheral vascular disease (history of claudication), or pulmonary disease (dyspnea on exertion of one flight or less; abnormal breath sounds on auscultation) will not be studied
- Subjects with a history of any serious hypersensitivity reaction to the study medications
- Prisoners or subjects who are involuntarily incarcerated
- Subjects who are compulsorily detained for treatment of either a psychiatric or physical (e.g., infectious disease) illness
- Subjects with known allergic reactions to the study medications or test meal
- Subjects unwilling or unable to provide informed consent
- Subjects determined by the investigator(s) to not be appropriate candidates for the study
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT02104739
Please refer to this study by its ClinicalTrials.gov identifier: NCT02104739
|United States, Texas
|University of Texas Health Science Center at Houston
|Houston, Texas, United States, 77030
Sponsors and Collaborators
The University of Texas Health Science Center, Houston
The Center for Clinical and Translational Sciences (CCTS) Clinical Research Unit at The University of Texas Health Science Center at Houston
|Principal Investigator:
|Absalaon D Gutierrez, MD
|University of Texas Health Science Center at Houston, Dept. of Medicine
More Information
Keywords provided by Absalon D Gutierrez, The University of Texas Health Science Center, Houston:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Absalon D Gutierrez, Assistant Professor of Medicine, The University of Texas Health Science Center, Houston
|ClinicalTrials.gov Identifier:
|NCT02104739 History of Changes
|Other Study ID Numbers:
|Study First Received:
|April 1, 2014
|Last Updated:
|May 4, 2017
Keywords provided by Absalon D Gutierrez, The University of Texas Health Science Center, Houston:
diabetes mellitus type 2
exenatide ER
Additional relevant MeSH terms:
Prediabetic State
Glucose Intolerance
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Hypoglycemic Agents
Physiological Effects of Drugs
Hormones, Hormone Substitutes, and Hormone Antagonists
Dipeptidyl-Peptidase IV Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on September 21, 2017


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Kennel for Canines Fundraiser – Phase Two
In 2013 we launched the "Kennels for Canines" Fundraiser, remodeling our small dog kennels and what a difference it has made for the animals in our care. This year take the next step in our improvement process. In the second phase of "Kennels for Canines", we seek to raise enough money to provide similar upgrades to the large dog kennels. That include areas for dogs that have arrived at the shelter as strays and cruelty cases.
With your support we will be able to provide all our dogs with accommodations that they deserve. Please donate as generously as you can. Thank you for your support.


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Rainbow Coral Corp. (OTCBB: RBCC) biotech subsidiary Rainbow BioSciences and Amarantus Biosciences (OTCBB: AMBS) have moved into the final stages of the terms for a deal. The pending joint venture agreement will see the two entities working together to move the Amarantus NuroPro Parkinson's diagnostic platform towards commercialization. "This is a cutting edge approach to diagnosing a debilitating disease that has afflicted millions of people worldwide," said RBCC CEO Patrick Brown. "The marketplace is crying out for new breakthroughs in the diagnosis of neurological diseases, and we believe NuroPro has the potential to diagnose Parkinson's disease early allowing physicians to initiate treatment regimens earlier, as well as conduct research of clinical-stage disease-modifying treatments on earlier-stage patients." The deal is being structured to enable completion of the final stages of the NuroPro program, resulting in a commercially viable product to be introduced to the market place. NuroPro is being developed for the diagnosis of Parkinson's disease. The NuroPro test works by identifying differentiated levels proteins and peptides in the blood of patients who have Parkinson's disease, versus those who do not. NuroPro has completed a Phase 1 human clinical trial. The companies expect to initiate Phase 2 clinical studies in 2013. It is expected that upon completing Phase 2, NuroPro would begin generating revenue through sales under the Clinical Laboratory Improvement Amendment (CLIA) certification. "Amarantus' focus on Parkinson's disease has allowed it to gain considerable traction with partners who understand the potential value of the technologies we have in-house," said Gerald E. Commissiong, President & CEO of Amarantus. "This transaction will allow Amarantus to gain upside from the licensing of the NuroPro asset, while defraying the costs of the project in order to focus our internal resources on the MANF Program for Parkinson's disease and Traumatic Brain Injury. As NuroPro advances towards commercialization, we expect it could become a key differentiating component of our clinical development program of MANF for Parkinson's disease."
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No. 24 Norton by Symantec Leads but Suffers DNF After Contact
BRASELTON, Ga. (October 21, 2012) - No. 24 Norton by Symantec Porsche 911 GT3 Cup co-drivers David Calvert-Jones, Michael Avenatti and Andrew Davis and the Competition Motorsports team rode a roller coaster of emotions throughout Saturday's American Le Mans Series presented by Tequila Patrón Petit Le Mans until an incident denied them a checkered flag in the grueling endurance race.
Because he started from the pits, ALMS rules required Davis to serve a stop-and-go penalty. Unfortunately, the pit road speed limiter would not engage when he came in and Davis received a stop-and-go plus 20 seconds penalty for speeding on pit lane. Already running in last place, the second penalty forced Davis one lap down to the GTC leaders.
"Most of my first triple stint, I was driving pretty angry because I was upset about starting in such a big hole," Davis said. "But I love Road Atlanta, I grew up here and I just pushed as hard as I could. I'm really excited that we were able to get the No. 24 Norton by Symantec Porsche up front. It was a lot of fun leading those laps and everybody was pumped up about that."
Davis led for 30 minutes before bringing the yellow and black Porsche onto pit road to turn the car over to Calvert-Jones for his first ALMS race experience. With nine podium results from 12 starts in his just-completed rookie IMSA GT3 Cup Challenge by Yokohama season and a runner-up performance in the Gold Cup championship, CJ was well prepared for the race.
However, the Petit Le Mans was substantially different than any race CJ had previously driven, as he'd never raced in prototype traffic, never made pit stops and the longest he'd ever driven was 45 minutes. All of that changed on Saturday, as the Aussie dealt with traffic from faster classes on every lap.
He got familiar with pit stops - including a couple unscheduled stops - and spent just shy of three consecutive hours in the cockpit in the heat of a warm early fall afternoon in Georgia. Despite the steep learning curve, CJ was able to keep the car in contention for a top-five result and turn the car back over to Davis in fifth place.
"I'm not sure if I can describe the experience," said Calvert-Jones. "It was like no other racecar experience I've had. It was all pretty foreign, I'd only had a little while in the car, and it's one thing to go out there and practice with the P1 cars and all the faster cars, but when they're racing, it's a whole different story. When you've got GT cars coming through, the Porsches, the Corvettes and the Ferraris, and they're all racing and they're freight training and you're getting pushed around, it's mind blowing."
Davis drove a quick second stint before turning the car over to Avenatti while still running in fifth place. Like his co-drivers, Avenatti also put in a solid effort to keep the car in contention for a top five. Sadly, an impatient prototype "punted" the No. 24 Porsche off course at the top of the Esses, sending Avenatti hard into the barrier.
He was ultimately able to drive the car back to the pits, but with substantial damage to the front end. The team made an effort to get the car back on course without its front bodywork - which it did for a few more laps - but it became clear that there was nothing to be gained and a lot more to lose, so the decision was made to take the car back to the paddock and out of the race after seven and a half hours.
"From my perspective, I had position in the corner and a prototype came out of nowhere, drilled me in the right rear and sent me on 'Mr. Toad's Wild Ride,'" Avenatti said. "All in all, it was a rough week, but it was a pretty good race, at least the first few hours of it. Andrew did a phenomenal job overcoming some significant adversity to bring the car to the front. It was great to have Norton by Symantec on the car and it was great to drive with CJ. We had a lot of fun this weekend. While the result may not show it, all in all, I thought it was a pretty productive weekend."
Despite the disappointing end result, CJ was pleased with his first Petit Le Mans experience, and is "dangerously" hungry for another endurance racing opportunity.
"It was very exciting to see Andrew get that car the way he did to the front of the pack," CJ said. "It was just the most amazing drive that I think I've seen ever. I was also excited that Norton by Symantec gave me the opportunity to compete in the GTC class in the ALMS race at Petit Le Mans. It's been two months of planning and preparation to get here, which I was very excited by, and it's been an experience like none other for me in my racecar career. Everyone that's helped us to get us to this point, obviously, I'm really grateful for: Norton by Symantec, Blundstone Boots, mobilesecurity.com, Koss Stereophones, JRZ Suspension and Bob Faieta of Competition Motorsports and all his crew. It's been an amazing experience."
Source: David Calvert-Jones


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Feathered Round Haircut
Density and feathery tips are concentrated in a short, geometrical cut surrounding her face with a bright platinum blonde glow. Bluntness and fine texture are combined for a strong look with a soft edge and a definite seduction factor. The hair is short enough to wear the new high collars or, as seen here, a magnificent satin bow around the neck.
To create a subtle asymmetry the shape was shifted ever so slightly and a long, dainty strand was pulled into her face above one eye. Perfect ratio in shape and form make this modern hairstyle an instant classic.
Collection: 2005/6 Collection
Hair: HOB Artistic Team
Art Direction: Akin Konizi @ HOB Salons
Photography: Thomas Warwick
Make-up: Stefane Knight
Styling: Robert Morrison
Products: Wella
Related posts:
Short hairstyles
Very short platinum blonde haircut


text: A carrier ship with an interesting resident. Not much is known of its history but Splitsie and Capac are on the case! Retrieved from "http://light-echoes.wikia.com/wiki/RX-394?oldid=126" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Ship Add category Cancel Save


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Mesa brings back Hall of Honor with 4 new members
For the first time in four years, the Mesa State Hall of Honor will welcome a new class of inductees.
Former coaches Jack Perrin and Doug Schakel and former student-athletes Tracy Bennett and Pam Glenn Hager will be in the 2010 Hall of Honor class.
"It's a great class," Mesa State Athletic Director Butch Miller said Wednesday after the class was announced. "Schakel is a legend around here. He's meant a lot to the college. I didn't get to see Bennett play, but I remember the name.
"Pam was a player here when I was here. I remember how good she was and the run those teams had. Jack has meant a lot to Mesa State College as well."
This is the first Hall of Honor class since 2006, when Christopher Allen, Hugh Cook and Kristi Courter were inducted. This is the 12th class to be inducted. The first Hall of Honor class was in 1996.
Bennett, Glenn Hager, Perrin and Schakel will be inducted Jan. 15, 2010, at Brownson Arena. They will be honored at halftime of Mesa State's men's basketball game against the University of Colorado-Colorado Springs at 8 p.m. on Jan. 16.
"The Hall of Honor is a special place in the department," Miller said. "I'm excited to get it going again. We weren't getting the numbers of applicants. It's something we'll try to do every other year, instead of every year. We're excited to have it back."
Bennett was a two-time NAIA All-American and two-time All-RMAC kicker for the football team from 1986-1989. During his career, the Mavericks advanced to the NAIA quarterfinals in 1986 and 1988. He holds school records for most point-after attempts in a season (60, NAIA record), career (185), most points by a kicker in a game (18), season (103, NAIA record), career (354) and tied for the longest field goal (54 yards).
After his football career, Bennett, a Grand Junction High School graduate, started a career as a photographer and founded ChipShot Films. He lives in the Los Angeles area.
Glenn Hager was a three-time All-RMAC volleyball player from 1992-95 and an RMAC Tournament Most Valuable Player. She ranks second all-time in school history in total blocks (649), block assists (482), digs (1,783) and games played (528). Glenn Hager made Mesa State's Dean's List and President's List. She is a teacher and coach at a junior high school in Casper, Wyo.
Perrin led the Mesa football team from the junior college ranks into the NAIA. Under Perrin, the Mavs won four Intermountain Collegiate Athletic Conference titles and achieved a No. 2 national ranking in the National Junior College Athletic Association. He was the RMAC Coach of the Year in 1977 and had seven players play professionally.
Schakel served as Mesa State's men's basketball coach, teacher and athletic director before retiring. In his 18 seasons as the men's basketball coach, he posted a 304-195 record (.609 win percentage) and led the Mavericks to six RMAC championships.
Schakel developed the Mesa State Basketball Camp in 1978, which is now among the largest camps in the country.
He coached nine All-Americans and several Academic All-Americans.
Schakel was Mesa State's athletic director from 1979-1981 and again from 1998-2001.
In 2001-02, he was an assistant coach for Steve Kirkham's women's basketball team, which became the first RMAC women's basketball program to host an NCAA Division II regional tournament. In Schakel's 30-year coaching career, he won 503 games and lost 285.


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Scientific Publications by FDA Staff
Search Publications
Pharmacoepidemiol Drug Saf 1995 Jul-Aug;4(4):195-206
Testing for clustering in record linkage databases
Hammerstrom T
One way to identify an excess risk of an adverse event during drug exposure is to use administrative, medical, and pharmacy records data, such as Medicaid or HMO (Health Maintenance Organization) records, to compare the relative frequency of the suspect event in exposed and unexposed periods. Such estimates can be seriously biased if there is clustering in patient visits to physicians and pharmacies. This paper presents two simple tests for determining whether the patient visit dates in such a database are Poisson processes of visits or clustered processes. The paper shows that this test is quite powerful at detecting both clustered sequences and nearly regular sequences of visits. Finally, it gives a straightforward SAS program which will carry out the tests.
|Category: Journal Article
|DOI: 10.1002/pds.2630040402
|Includes FDA Authors from Scientific Area(s): Drugs
|Entry Created: 2012-11-12