text: Diagnosis By Mayo Clinic Staff Print Your doctor will start by asking about your medical history and doing a physical exam, including examining your chest with a stethoscope. To determine if you have pleurisy, your doctor might recommend: Blood tests. A blood test might tell your doctor if you have an infection. Other blood tests also might detect an autoimmune disorder, such as rheumatoid arthritis or lupus, in which the initial sign is pleurisy. Chest X-ray. A chest X-ray can show if your lungs are fully inflating or if there is air or fluid between the lungs and ribs. Your doctor might recommend a special type of chest X-ray in which you lie on your side (decubitus chest X-ray). Computerized tomography (CT) scan. In a CT scan, a computer translates information from X-rays into images of thin sections (slices) of your chest, producing more-detailed images. A chest CT scan can show if there is a blood clot in the lung or find other causes of pleuritic pain. Ultrasound. This imaging method uses high-frequency sound waves to produce precise images of structures within your body. Your doctor might use ultrasound to determine whether you have a pleural effusion. Electrocardiogram (ECG or EKG). Your doctor might recommend this heart-monitoring test to rule out certain heart problems as a cause for your chest pain. Diagnostic proceduresIn some cases, your doctor might remove fluid and tissue from the pleural space for testing. Procedures might include: Thoracentesis. To remove fluid for laboratory analysis, your doctor might suggest thoracentesis. In this procedure, your doctor injects a local anesthetic between your ribs to the area where fluid was seen on your imaging studies. Next your doctor inserts a needle through your chest wall between your ribs to remove fluid for laboratory analysis. Your doctor might insert the needle with the help of ultrasound guidance. Thoracoscopy or pleuroscopy. If tuberculosis or cancer is a suspected cause of your condition, your doctor might perform a procedure that allows for direct visualization inside your chest to look for any abnormalities or to obtain a tissue sample (biopsy) if needed. Symptoms & causesTreatment Nov. 12, 2016 Print Share on: FacebookTwitter References What are pleurisy and other pleural disorders? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/pleurisy/. Accessed Sept. 12, 2016. Ferri FF. Pleurisy. In: Ferri's Clinical Advisor 2017. Philadelphia, Pa.: Elsevier; 2017. https://www.clinicalkey.com. Accessed Sept. 12, 2016. Mason RJ, et al. Pleural effusion. In: Murray and Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Sept. 12, 2016. Kliegman RM, et al. Pleurisy, pleural effusions, and empyema. In: Nelson Textbook of Pediatrics. 20th ed. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed Sept. 12, 2016. Patient information: Pleuritic chest pain. http://www.uptodate.com/home. Accessed Sept. 12, 2016. Lee YCG. Diagnostic evaluation of pleural effusion in adults: Additional tests for undetermined etiology. http://www.uptodate.com/home. Accessed Sept. 12, 2016. Sheski FD. An overview of medical thoracoscopy. http://www.uptodate.com/home. Accessed Sept. 19, 2016. RelatedSymptom CheckerCT scanUltrasoundChest X-raysWhipple's diseaseShoulder painShortness of breathCough PleurisyOverviewSymptoms & causesDiagnosis & treatmentDiagnosisTreatmentPreparing for your appointmentSelf-managementMore aboutIn-DepthMultimediaResources Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Store Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. The Last Diet You'll Ever Need4 Simple Steps to a Joy-Filled LifePain Management Strategies from Mayo ClinicStop Osteoporosis in its TracksProtect and Preserve Your Vision Diagnosis & treatmentRequest an AppointmentDiagnosisTreatmentPreparing for your appointment CON-20164035 Patient Care & Health Information Diseases & Conditions Pleurisy


text: The claim that SpongeBob makes your child dumber is a causal claim. If you do X, Y will happen. To prove that, you'd have to show that if you forced the children in the no-TV households to watch SpongeBob and changed nothing else about their lives, they would do worse in school.

subset: commoncrawl


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Only about FIVE months until we leave Korea!! FIVE!
Wow- it's all going by so fast! We have spent most of our marriage here together, and soon we will leave.
Although we have been here 4.5 years, sometimes it still isn't easy. Korea is still, after all, a foreign culture. Language is different, logic is different, expectations are different and FOOD is DIFFERENT!
I have had a love/hate/love/hate relationship with Korean food in my past 4.5 years here. When I arrived in Korea I was SUCH a picky eater! Not such a good thing when almost every Korean dinner out looks like this-
Then, after I got past the shock, I started opening up and trying new things! "New things"= fish and MUSHROOMS! How exotic, I thought! ha! After I was starting to get along with the idea of Korea food... I converted to a vegetarian/vegan. Things changed slightly.
I'm lucky that the pre-school I teach at offers free lunch to the teachers. It's a great way to experience Korean food! Most of the food I can't eat because of the cow bones, fish broth, seafood, etc- and that's ok with me. But some days.... oh boy! SOME days, I really luck out! This was the case last Thursday. I had a delicious broccoli, mushroom and DEVIL'S TONGUE JELLY side dish!! YUM!!!
Have you ever heard of Devil's Tongue Jelly? In Korean it's called "gon yak" (곤약), in Japanese it's called "konnyaku". It comes from the root of a plant that grows in subtropical Asia- most refer to it as a potato or yam. It is for the most part, tasteless and will absorb any flavor you marinate it in! Wow- it is such a great addition to meals!
The Japanese call it "The Broom of the Stomach". It is referred to as such because of it's ability to "clean out" your colon- it's used for such in Chinese traditional medicine for this reason. This is how it made its way to Korea so very long ago.
In addition to the high fiber content, Devil's Tongue Jelly also has starch, protein and almost no calories because so much of it is made of water. In some studies it has been shown to normalize cholesterol, blood sugar and blood pressure! For all of these reasons, it is a very popular diet food for women in Korea. Not that I'm advocating it to be used as such!
So, I decided to give cooking with DTJ or "gon yak" a try! At the store, I was surprised to find only the white kind. If you're here in Korea, you can find it in the area where all the kimbap making supplies are. Here's what I got-
Here's my American-Korean fusion recipe. I'm calling it:
Sounds like a witch's brew! Perfect for your Halloween Dinner Party!
- 1/2 brick of Devil's Tongue Jelly
- 8-12 mushrooms (depending on size)
- 2 cups of chickpeas (garbanzo beans)
- 1/2 of an onion, chopped
- 1/4 cup organic Tamari (soy sauce)
- 4 Tablespoons apple cider vinegar
- 4 tablespoons coconut oil
- 2 Tablespoons blackstrap molasses
- 3 teaspoons sesame seeds
- 2 cloves of garlic
Serve with soaked quinoa and spelt or other whole grain and a side of steamed broccoli.
I started by opening the bag and pouring its water out, then I rinsed it a few times until the smell was gone. You'll know what I mean when you open the bag.
Next, I cut it the package in half and cut it then into cubes.
|Check out my new ceramic knife!! Woo hoo! LOVE it!
Next, I marinated the cubes in 2 TBSP of apple cider vinegar and 1/8 cup of Tamari. You could also use Soy Sauce, or Shoyu, they are all similar.
|I marinated it just for a few minutes while I was preparing other things.
Next, I added in the chickpeas and the other 1/8 cup of tamari and 2 TBSP of apple cider vinegar. I cooked everything for about 2 or 3 minutes.
After that, I put in the mushrooms and Devil's Tongue Jelly along with the remaining tamari in the bowl.
I let everything cook on Medium High heat until all the water started coming out and looked like this.
|See how it looks bubbly?
I didn't add the broccoli to the stir fry because I wanted to keep as much of it's nutrients intact. I've been craving broccoli, sesame, chickpeas and almonds lately. My first thought- maybe my body is needing extra Calcium right now! So, I gladly indulged. Check out the nutrition in just 1/2 of the meal. Keep in mind, this is only 1 out of 3 for the entire day! Wow!
I'm going to try to soak in as much Korean food as I can in my last 5 months here. I love finding new cultural foods to add to my repertoire.
Have you ever tried Devil's Tongue Jelly? What were your thoughts? Also, PLEASE let me know if you have any good recipes using it (I still have a half of a brick left)!
I'm leaving tomorrow night for Japan! We have a 5 day weekend here in Korea thanks to the Korean harvest festival (Chusok). Can't wait to hike Mt Fuji and sip some tea in Kyoto with my hubby!
Details on Japan and that new "Client Access" tab at the top coming to the blog soon- can't wait to share!
Try a new food.
Listen to your body.
Soak your grains.
Live your life,
The Empowered Way


text: Seller: pendulum.man (24,193) 99.2%, Location: Buckinghamshire, Ships to: Worldwide, Item: 201416512074 Details: One Pair Of Replaceable Pivots For That Clock Repair Size 5 These pivots are ideal for jobs where re-pivotting is not practical or feasible, just the job for clock repairers and hobbyists alike. The pivot needs to be a tight fit on the arbour and secured with a Loctite Retaining Compound (not super glue) This tables gives the dimensions and the other sizes that can be found listed in my eBay shop. Number 'C' 'B' 'L' Pivot Ø Bore Overall Length 1 0.55mm 0.95mm 3.80mm 2 0.65mm 1.30mm 3.50mm 3 1.05mm 1.80mm 5.00mm 4 1.60mm 1.90mm 6.50mm 5 1.60mm 3.20mm 7.00mm 6 2.00mm 4.00mm 9.00mm I am happy to combine multiple items to save on postal and packing costs. Thank You questions comments send email Powered by eBay Turbo Lister


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Kansas kids
Timothy, 9, is a loving child. He enjoys riding his bike and looking at cars and trucks. He loves looking at car magazines and has been known to do this for extended periods of time. He does very well with keeping his room clean. Timothy will need a patient family who can provide constant supervision and plenty of one-on-one attention.
To learn more about adoption, visit www.adoptkskids.org or call (877) 457-5430.


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ORLEANS, France (Jun. 29)
The lives of French Jews in this provincial city have returned to normal some three weeks after unfounded rumors were circulated that Jewish tradesmen were drugging and kidnapping women customers and selling them as white slaves to Middle East brothels.
Calm has returned to this Loire community, but Jewish shopkeepers in the city's main shopping area are not doing the business that they once did. Most of them expressed a wish to continue living here in hopes that, with time, life will return to its old ways. One or two however still insist that they intend to emigrate to Israel.


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London/Islamabad: Cricketer-turned politician Imran Khan's former wife Jemima Khan has praised the success of his political party Pakistan Tehreek-e-Insaf (PTI), which was set to form government in the restive Khyber-Pakhtunkhwa province.
An elated Jemima said that it was a great success for a political party, which once held just one seat the parliament, Geo News reported.
Imran Khan's party said early today it would form the next government in Khyber Pakhtunkhwa province.
"For Tehreek-e-Insaf it is a big day, a golden day," PTI leader Assad Omar said.
"A party which has no existence in parliament has emerged the second largest national party and the leading party in Khyber Pakhtunkhwa where God willing it is going to form a government," he said.
"Perennially perplexing that so many still vote for leaders who've been tried, tested & failed multiple times (& dismissed for corruption)" 39-year-old Jemima said in a twitter message.
London-based Jemima, in another twitter message, lauded Pakistanis for turning out to vote in the face of all the terror threats.
She also tweeted that their sons were wearing Imran Khan's kurtas yesterday.
Jemima earlier had also said that she was praying for peace and safety of Pakistanis during the polls.
She had married Imran Khan in 1995. The couple got divorced in 2004.
They have two sons Sulaiman Khan and Qasim Khan from the nine-year marriage.


text:
UAF Math & Stat Lab
The Math and Stat Lab is available to any student registered for a UAF MATH or STAT course. This is a drop-in tutoring lab, so no appointment is necessary. Students can use the area to work on homework with tutors nearby. Tutors can help with understanding concepts, reviewing prerequisite material, or helping to clarify problems. The lab also has computers and a printer for student use.
To see which courses the tutors can help with see the Math and Stat Tutor Page.
If you have any questions or concerns about this service please email email@example.com


text:
Saluting our troops this Veterans Day – Thank you for your service.
Vintage Jeep® Ad | MacArthur Returns to the Philippines
3 Responses to "Vintage Jeep® Ad | MacArthur Returns to the Philippines"
Thank you for this!
Remembering all the veterans on this day.
not just Americans 🙂 the dutch were deployed there too my grandfather served there for the royal dutch army and was in camp there and as a sergeant he broke out to get meds for his fellow men. also when hiro got nuked he stole the camp comm bayonet that still hangs on my grandmothers wall . R.I.P grandpa.
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text:
Textbook-Integrated Guide to Educational Resources
Chemistry in Focus: A Molecular View of Our World by Tro
15 The Chemistry of Household Products
15.6 Hair Products
All Videos
Videos: 12 results
Nature of Proteins
Effect of pH on solubility, denaturing proteins, hydrolysis in strong base, binding to coomassie blue, dying wool and cotton, gel filtration column, reaction of ninhydrin with amino acids and precipitating protein with ammonium sulfate are demonstrated.
Proteins / Peptides
Protein Reactions
Curdling milk, decomposition of hydrogen peroxide by catalase, glucose oxidase activity, hydrolyzing of sucrose with invertase, and using an enzyme to halt the Briggs-Rauscher reaction are demonstrated. Inhibiting the enzyme HIV-1 protease may slow the spread of AIDS.
Proteins / Peptides
Denaturation of Protein by Strong Acid
John W. Moore, Jerrold J. Jacobsen, Gary Trammell, Kristin Johnson
"Strong acid denatures egg white proteins.This video contains voiceover:""The tertiary structure of egg white proteins is held together by hydrogen bonding and hydrophobic interactions. Adding strong acid to the protein disrupts the intermolecular forces, and the tertiary structure is lost. The loss in protein structure is called denaturation. The proteins precipitate, forming a white solid."""
Acids / Bases |
Proteins / Peptides
Denaturing Proteins
Egg white proteins are denatured by acid, lead solution, and heat.
Noncovalent Interactions |
Proteins / Peptides
Hydrolysis of Protein in Strong Base
Concentrated sodium hydroxide causes wool and hair to dissolve.
Amino Acids |
Proteins / Peptides
Factors Affecting Glucose Oxidase Activity
Various factors which affect glucose oxidase activity are demonstrated.
Catalysis |
Enzymes |
Kinetics |
Proteins / Peptides
Halting the Briggs-Rauscher Oscillating Reaction
The Briggs-Rauscher reaction is demonstrated in three different ways. Catalase from a liver extract decomposes the hydrogen peroxide in an Briggs-Rauscher reaction, stopping the oscillations.
Catalysis |
Kinetics |
Enzymes |
Proteins / Peptides
HIV-1 Protease: An Enzyme at Work
This is "HIV-1 Protease: An Enzyme at Work", from a video tape published by the Journal of Chemical Education - Software as Special Issue 13
Applications of Chemistry |
Enzymes |
Proteins / Peptides |
Medicinal Chemistry
Safety Match Chemistry: Red Phosphorus and Potassium Chlorate
The chemical reaction that underlies common safety matches is demonstrated.
Applications of Chemistry |
Consumer Chemistry
Luminol and light sticks are demonstrated.
Thermodynamics |
Applications of Chemistry |
Consumer Chemistry
Formation of formaldehyde copolymers, nylon rope, high and low density polyethylene, combustion of polyethylene and polystyrene, Beilstein test, formation of solid latex, cleaning oil spills, slime, solid foams, super absorbent polymer, formation of polyurethane foam under normal and micro gravity, and construction of a rod climbing apparatus are demonstrated.
Polymerization |
Reactions |
Applications of Chemistry |
Consumer Chemistry
Reactions and demonstrations the explore thermodynamic concepts.
Precipitation / Solubility |
Solutions / Solvents |
Calorimetry / Thermochemistry |
Applications of Chemistry |
Acids / Bases |
Physical Properties |
Reactions |
Thermodynamics |
Gases |
Phases / Phase Transitions / Diagrams |
Water / Water Chemistry |
Liquids |
Solids |
pH |
Consumer Chemistry |
Kinetics |
Oxidation / Reduction
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text:
Rigaud AS, Traykov L, Latour F, Couderc R, Moulin F, Forette F. Presence or absence of at least one epsilon 4 allele and gender are not predictive for the response to donepezil treatment in Alzheimer's disease. Pharmacogenetics. 2002 Jul;12(5):415-20. PubMed.
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text: CLOT returns to its longstanding Levi's partnership with a new set of denim consisting of 505 jeans and a matching denim jacket. Following up on its previous platinum and gold installments, this new copper version features a wealth of cut-and-sew features highlighted by the use of copper metallic sew. In addition to the metallic thread element, CLOT finds inspiration from Robert Indianna's LOVE logo with its own reference in the form of a CLOT LOVE patch. Stay tuned for a release date soon.


text:
Funeral services for W. W. Robertson were held at 2 o'clock Sunday afternoon at the Berea Christian church, Rev. R. E. May officiated.
Miss Rita Jean Nall sang "Beautiful Isle of Somewhere" and "Going Down the Valley", accompanied by Mrs. Harold Stewart at the organ.
Caring for the many floral tributes were: Mrs. Frank Foster, Mrs. Ralph Robinson, Mrs. Carroll Robinson, Mrs. Russell Lewis, Mrs. Odell Young, Mrs. Wilbur Bruner, Mrs.Mose Wicks and Mrs. Wesley Petefish.
Pall bearers were Ralph Robinson, Carroll Robinson, R. E. Strawn, Marshall Robinson, George Robinson, Frank Foster, Charles Harris, Clyde ___.
Interment was in Berea Cemetery.


text:
Lil Wayne Confirms Formation of "Supergroup" with T-Pain
VH1 reported yesterday that Lil Wayne finally confirmed the rumors floating around that he's forming a "supergroup" with T-Pain. In typical Weezy, uh, succinct fashion, he confirmed it thusly: "Yeah." (T-Pain, however, was a little more talkative on the matter.)
Still, that's just two people; technically it would take at least one more person to make a supergroup instead of just a superduo. Wonder who the other member(s) would be?
Wayne also "announced" the June 27 beginning of his tour in support of Tha Carter III. Um, no kidding – his booking on the June 28 stop of Summer Fest here at the BankAtlantic Center has already been listed on Ticketmaster for a while. And if you haven't checked out the album yet, looks like you're in a serious minority – it's Soundscanned over a million copies sold in its first week of release. (For some perspective, the last album to sell over a mill in its first week came out in 2005; it was 50 Cent's The Massacre).
On a related tangent, will someone weigh in on what it's like to see T-Pain "live"? I saw him pop out for a minute during the Miami opening date of the Jay Z/Mary J. Blige Heart of the City tour – but that was just for a hot second, and, uh, he was kind of eclipsed by the bigger star onstage. What does he do? How much of it is actually live? Thinking about this makes me want to go for some butternut reduction…. – Arielle Castillo
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text:
Ask a Lawyer and Get Answers to Your Legal Questions
they're in Texas.. the rep., the file. I wish to followup as possible non-compliance to the subpoena
chevy dealer is independant, but is G.M.cust. service who i complained to/served to G.M.'s legal dept. They are not a defendant
sq. 1, on the idea of getting the rep. to answer a ques. as if in Pa...What difference where she sits her butt. it is the co.'s locale that matters?? No go, to that? Also, G.M. can be forced to comply w/ the co. policy info. in writing, though the legal dept. is out-of-state?
had to leave, but is the issue of where the person works preference,as to the co.she's employed? The info. I need happened w/company behalf,company employee info...I called the co., G.M.cust service, she picked up. They have overseas cust serv. reps. also. She intervened for the co., regarding a business of co. She should've included that info in my file,told me she did..a co. file
since she didnot write the1 answer down,there is no one else to give upp that info. That is why i'd depose her in writing,and serve the co.'s legal dept., preferably. 2ndly if not, her at trial would be good,since she'd be under oath. Ques. if I served her deposition ques.'s your saying she should have to answer by law of Pa., a Pa. subpoena sent to Texas
yet, if she did answer the ques. in writing, i'm good. It's in writing, so why not ask her to, you said i can do that and she should answer that subpoena, by law. You said that?right. tell the G.M. to save the problem if I subpoena her for court
got that of hearsay, i'll research that for sure 1st. otherwise, i'd request her for trial. Also, still i could serve my contempt of court to produce their policy of recorded talk of file same time as deposition to them, to be prepared for court. She could lie or forget by then. Cool, my file extends to this August with no say so of closing the file. Sounds like a lie to me. I misread the file. i believe they closed it 8/7 but my last 2 calls, early Aug. and late July were a request of my file also that i did earlier subpoenaed them for it. this 1st one of 7/8 asked for the tapes also of my file. i did it wrong by not including a Cert. of Compliance w/it. I was told to reissue another 1. I did. But I still called and asked for them to obey it, if they would, and if they even got the document? It is recorded in my file 2x. So they must have deleted the tape recordings after this as my file was ongoing then. So they knew i wanted the tapes I even e-mailed them as to why, that is recorded intact. POINT is can I say this bit of INFO in My contempt of Court for their policy, when they start their 30 days, and that time I had allready subpoenaed that, and e-mailed &called for it.. Who's to say I still would've followed up that 1st one w/ a Contempt of Court, right
hi, may i include that in my contempt,they erased tapes even under subpoena and sought to get them to comply
1 last thing, for the written deposing..you saidi do that by getting a subpoena with that?


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If a hint means what it appears to, the first 2017 Chevy Bolt EVs could be in customers' driveways before this time next year. The revelation came from none other than President of General Motors North America, Mark Reuss in response to a Dec. 5 Facebook post by EV advocate Chelsea Sexton. Showing a photo […]+ Read More
If an anonymous source speaking to the Wall Street Journal is correct, GM may have an extra added bonus alongside the 2016 Volt this Monday – a 200-mile range Chevrolet Bolt EV concept due by 2017. It's already been reported that GM says it will compete with Tesla's Model 3 also due reportedly by 2017, […]+ Read More
In a teaser within Chevrolet's latest new Volt teaser video, GM's Mark Reuss caps off a discussion of improved ride quality with even more relevant info when he looks at the range indicator and exclaims that he sees something "very exciting." "What do I see here from a range standpoint? says Reuss smiling. "Holy cow!" […]+ Read More
It can be tough trying to oust a popularity contest favorite even if you too have a pretty face, and a fair degree of talent. And so it has been thus far for Chevrolet's Cruze Turbo Diesel that went on sale in June 2013 with a German Opel engine refined at GM labs in Torino, […]+ Read More


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Maury Regional Medical Center will host two meetings Tuesday aimed at helping community members learn about the prevention, care and management of two life-threatening diseases.
Maury Regional Medical Center will host two meetings Tuesday aimed at helping community members learn about the prevention, care and management of two life-threatening diseases.
The Diabetes Education Group will meet at 11:30 a.m. in Private Dining Room One on the medical center�s ground floor. Maury Regional Emergency Services Community Outreach Coordinator Doug Rutherford will discuss the effect of weather on blood glucose control.
�Diabetes is one of the most prevalent, yet preventable diseases in Middle Tennessee. Learning about and practicing healthy living habits greatly decreases your risk for diabetes and diabetes-related complications,� said diabetes educator and support group coordinator Donna Shedd, R.N. �We invite anyone interested in learning more about how to stay healthy during the summer months to join us on June 4.�
The Diabetes Education Group meets monthly on the first Tuesday of each month. More information is available by calling (931) 380-4324.
Lungs for Life, the COPD support group, will meet 2 p.m. Tuesday in Private Dining Room One. COPD, or chronic obstructive pulmonary disease, refers to a group of diseases that block airflow and make it increasingly difficult to breathe. Emphysema and chronic bronchitis are the two main conditions associated with COPD.
At this meeting, Karen Miller, R.N., and Jacqueline Hill, EP, will discuss the early signs and symptoms of heart disease and the correlation of COPD to heart disease. Lungs for Life meets quarterly on the first Tuesdays of March, June, September and December. For more information, call (931) 380-4094.
There is no charge to attend these meetings, which are open to the public. For more information about these and other support groups and community events hosted by MRMC, visit mauryregional.com.


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For Laverne D'Silva, earning her spot as valedictorian at Tampa Bay Technical High School meant missing social events to study alone in her room.
That was okay because soon she would trade report cards for dorm parties and car rides to school for morning walks to class.
When acceptance letters from Florida's major universities started arriving in the mail, she set her heart on the University of Central Florida.
Then her parents, both of whom are in the tech support business, started talking finances. If she went to school in Orlando, she would graduate from college in debt. If she lived at home in Brandon and went to the University of South Florida, she would come out ahead.
Staying put was the sensible decision.
"At first I was disappointed, but when I sat down and really looked at everything, I knew USF was the best choice," said D'Silva, who will graduate Thursday from Tampa Bay Tech's health science program with a 6.75 GPA.
• • •
This year, Hillsborough educators say that high school graduates are considering the sagging economy as they make decisions about their future. Honor graduates enroll at local or community colleges to minimize costs. Students choose majors based on the job market. And scholarship recipients who receive more than enough money to pay for school-associated costs save the difference for an uncertain future.
"(Students) are worried about the economy and thinking long term," said Theresa Nissen, college and career counselor at Armwood High School.
Applications to local colleges and universities are soaring. Freshman enrollment at Hillsborough Community College has more than doubled since 2008, said college spokeswoman Ashley Carl.
Record numbers of Hillsborough County students applied to USF since the economy slumped, so many that getting into the school has become tougher.
In 2005, more than 60 percent of applicants from Hillsborough County gained acceptance into USF, according to the Times.
Last fall about 3,771 Hillsborough students applied. Only 1,909 were admitted, at least a 10 percent decline, university records show.
In addition to accepting Bright Futures, USF offers freshman scholarships for Florida residents and other financial incentives to applicants with exemplary school records.
"We are definitely seeing an increase in the quality of students that are applying," said Robert Spatig, the university's director of undergraduate admissions.
Kayla Propst, who graduates from Armwood High on Monday with a 5.6 GPA, opted to go to USF rather than her dream school, Ohio State University.
Out-of-state costs, including textbooks and living expenses, totaled $33,000 a year, Propst said.
She will pay nothing out of pocket to go to USF, thanks to her Florida Bright Futures Scholarship and financial aid.
Propst, who plans to major in accounting, will live at home in Seffner and cram a full load of classes into two days. The rest of the week, she'll work as a cashier at Winn-Dixie to help her mother with day-to-day expenses.
"Paying for college life is my responsibility, not hers," Propst said.
Durant High graduate Ashleigh Powell plans to pay for USF with a Bright Futures Scholarship and support from her grandparents. She considered UCF but decided to stay at home in Valrico to start a savings fund.
"I will be able to make a down payment on my own home my first year out of college with the money I saved," she said.
• • •
D'Silva, the Tampa Bay Tech grad, said most of her friends are staying local.
Honors graduate Rikesh Patel was accepted at the University of Florida, but USF offered him $6,000 more in scholarship money. By staying home in Tampa, he doesn't have to work and will have more time to study. He plans to major in biology and wants to go to medical school.
"I think sometimes when people go away to school, their grades slip," Patel said. "This way I might do better."
Neither Patel nor D'Silva worries about their parents getting in the way of their social life. They plan to participate in campus activities and hang out at football games. D'Silva, a high school soccer player, hopes to play on the Bulls team.
"We can still have the college experience," she said. "Leaving home, that was our dream, but it's just not possible now unless we want to go into debt."
Reporter Justin George and Kelly Price of tb-two* contributed to this report. Sarah Whitman can be reached at (813) 661-2439 or [email protected]


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NEW YORK (Mar. 27)
Israel Government and party leaders, including Prime Minister David Ben Gurion, will urge the Parliament to grant special status to the Jewish Agency for Palestine as the instrument through which world Jewry can continue to participate in the country's immigration, absorption and colonization programs, it was stated here today by Dr. Nahum Goldmann, chairman of the American section of the Agency, who last night returned from a trip to Israel.
Dr. Goldmann said that appropriate legislation would likely be submitted in time for parliamentary approval before the convening of the World Zionist Congress, scheduled to take place in Jerusalem some time this summer. As at present contemplated, the bill would specifically define the powers and responsibilities of the Jewish Agency; set up an enlarged Joint Development Authority, on which the Government and Jewish Agency would be represented; provide means for assuring that the work of other Jewish organizations in Israel would be coordinated with that of the Jewish Agency.
Declaring that the name of the Jewish Agency will be changed to "Jewish Agency for Israel," Dr. Goldmann said: "I must emphasize that the Agency's proposed special status would not impinge one iota upon the loyalty of Jews to the country of their present citizenship. The proposed status involves no more than cooperation in a non-political, humanitarian task of great magnitude–the absorption of hundreds of thousands of homeless human beings into Israel–and would leave the Government of Israel with absolutely unimpaired sovereignty over the political affairs, internal and external, of the state."
Dr. Goldmann said it has not yet been decided whether the "status bill" would be presented for approval to the present parliament, or would be held over for submission to the new parliament to be chosen at Israel's national elections, now scheduled for July. He added that the Zionist Congress would open a fortnight after the elections took place.


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Woman Texts Person Who Stole Van, Van Is Returned
File this in the "wow, you don't hear that every day" category.
A single mom's van was stolen from a store in Missouri. She remember that her husband's cell was still in the car, so she sent it a text and asked that the van be returned.
The text said something like "you just stole a single mother of five's only vehicle and you're ruining my life." Around six hours later, the van still wasn't returned. So she sent another text and asked if the thief would just "drop it at Quick Trip." The thief eventually texted back and told her where she could find it.
And she says that even if the thief was identified and caught, she wouldn't press charges.


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Southend Blogger Jack Monroe writes here about increases in the price of basic foods:
As someone who buys pretty much the same items every week, spending around a tenner a time, I know the prices of the Sainsburys Basics range by heart. Bread is 50p a loaf, whether white or wholemeal. Chopped tomatoes are 33p for a cardboard carton. Kidney beans are 18p for a tin. Apples are 82p. Sainsburys Basics strawberry jam was, the last time I checked, 29p a jar. Not today. Today it was 35p a jar. People will be rolling their eyes now, that I'm quibbling over 6p, but it's not the only 6p hike in the Basics range…
… Again, I can almost hear the tuts. "Oh, it's only 6p, what's she going on about?"
What she's going on about, is the price of food. Strawberry jam is 120% of the price of strawberry jam two weeks ago. If in some horrible world, the inflation of the price of food carries on at that rate, it will be 42p in a fortnight, and over £40 a jar by the end of the year. Of course that won't happen, but it's a demonstrative figure as to how effective that 'small' 6p hike could be.
Having worked for one of the 'big four' supermarkets myself, I know how they work. Essential items like bread and milk are at the periphery of the store, and down the middle is what ASDA used to call 'action alley', where promotions are piled high and sold cheap. Tins of Christmas chocolates 3 for £10. Crates of beer 2 for £20. Never anything nutritious, or necessary, but marked down and boldly signposted ….


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-------------------LGnation postForgeHub post------------------- Introduction: I think most of us forgers were at least a little disappointed to find that there were no new forge items in Cold Storage and that there wasn't too much forge potential. But as I did with every new map, I switched to a monitor and flew around the map looking at everything that Bungie had put into it. I still got no inspiration. But when I came here, the file forums were full of good (and terrible) Cold Storage maps, so I tried again. This time I made sure I explored everything . And it just so happens that I stumbled upon a small crevasse in the ceiling above the sniper and active camo spawn. This gave me an idea, and this map is a result of that.Note: this map includes one visual filter, Olde Timey, that is purely for aesthetics. It does not hinder sight in the map, and gives the chamber an amber color. While in construction I referred to the map as "The Amber Crevasse". The Creation of Storage Chamber This map was very hard and tedious to create. Part of the difficulty lay in the fact that I only had three different scenery objects to work with that would fit in the crevasse: Barricades, and Energy Blockers small and large. Barricades make up most of the map, as they make good floating platforms and stairs. They were hard to maneuver into the crevasse however, because the walls close in the higher up you are, and I had to rotate the barricades in interesting ways to make them fit or to move them higher. Energy blockers were slightly easier because some parts of them are only solid to weapons and players, but go through walls, floors, and scenery. This meant I could pull them up into the crevasse easier and they were easier to rotate, but my limited supply of them as well as their radiance made me use mostly barricades. To make map construction easier, I built this map from the top down, otherwise I would have had to move objects past others that had already been placed, but building from the top down made it difficult to visualize exactly how I wanted to lead to the level I had just built and whether it would work. I put the floor on after I placed all spawn points and most weapons, and that represented the completion of this difficult map. Map Geography and Description Storage Chamber can essentially be divided into four small levels: The first level is where a lot of the action and carnage will take place, as it is the easiest area to maneuver and fight in. This is at the very bottom of the crevasse that the map is built in and has clear floors so you can see out. There are teleporters and shield doors below the glass floor for aesthetics, but this area is unreachable. The bottom level is clear of obstacles apart from a small stair that is used to get to the second level.The second level is mostly clear as well, with another stair leading to the third. The larger portion of this level is made with energy blockers used as a floor, which is relatively smooth to walk on. Not much stands out on the second level, as it is mainly used as simply a fighting and traversing space.The third level is slightly slanted upwards, and features one of two crawlspaces that you can hide in. The crawl space is made up of barricades that are arranged so that there is a small space underneath one that, if crouched, you can hide in. Between this level and the fourth there is not one stair, but rather a small stairway made of barricades, which also features the second hiding spot. This is made by having two barricades positioned in a small square, the slanting one slightly to make an entry way above it. In this second crawl space can be found one of two power weapons, a single mauler. This can be retrieved by crawling into the small space.Before going on to the fourth and final level, you have the option of going to a small series of platforms in-between the third and fourth levels. This features one of two magnums, the only weapon that can headshot on the map, as well as a regenerator, which can barely be seen in the picture above, resting on an energy blocker above the two stairs.The fourth level is the topmost level in the map and is made entirely of energy blockers. There is only one way up, but two ways down. You can leave the way you came and drop onto the stairway between the third and fourth levels, or you can travel to the other end and drop all the way to the second level. This level was made extremely close to the ceiling of the crevasse, which features what reminds me of a ribcage, meaning you must crouch to travel under "ribs", but there is space to stand when between them. This level features the second power weapon, the sentinel beam, which is a desirable weapon to have in this map, as well as a bubble shield. This level, not including the mid level between third and fourth, will probably see the least fighting, because it is the most difficult to move in, but the sentinel beam and bubble shield will keep some people going there. Weapons The weapon set of this map is made to mostly be dual-wieldable guns. I wanted to have those close quarter dual wield battles be the focus of the map, and there's not really much choice with a space so small. I was careful about close range power weapons, and excluded a shotgun and an energy sword for fear of rushing to those power weapons, camping their spawns, and dominance while possessing them. The two semi-power weapons on the map, a mauler and a sentinel beam, are on long respawn times of 90 seconds, the mauler has no extra rounds, and are in mostly un-campable areas. They also do not necessarily dominate because any camp spot is easily hit by thrown grenades and then finished with any other weapon. The weapon set is as shown:Weapons Magnum x2Assault Rifle x2SMG x4Spiker x2Mauler x1Plasma Rifle x2Sentinel Beam x1Equipment:Frag Grenade x5Bubble Shield x1Regenerator x1 Supported Gametypes These gametypes are the only gametypes supported on the map, and I only recommend Free for All games, though team doubles style matches would probably work:-Any form of Slayer, team games not recommended-Any form of Juggernaut that does not require the juggernaut to reach destinations-Any form of King of the Hill, team games not recommended-Any form of Oddball, team games not recommended Supported Amount of Players At most this map can comfortably support six players. Going up to eight is okay, but may not work. Anything over eight will not be very fun. Ideal amount is four or five players, and three or less works fine. All Pictures These are all the pictures of the map. They include what is seen above, and more.The CrevasseFirst LevelSecond LevelThird LevelArea Between Third and Fourth LevelsFourth LevelStairway to Fourth LevelMauler Spawn/Hiding SpotHiding Spot on Third FloorRegenerator in UseBubble Shield in UseAction Shot: Fight on Second FloorAction Shot: Fight on First Floor[Edited on 08.22.2008 6:22 PM PDT]
=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=Community Reviewer: Destroying Ace=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-= Map Review-Description: 5/5Pictures: 4.5/5Map Idea: 4/5Map Quality {layout}: 5/5Map Quality {looks}: 4/5Comments: I like that you made the map on cold storage since I don't see very many maps on it. Accept, some of the screenshots are a bit confusing...... Though I can still figure out were it's at. The map looks good, accept it looks like there are some places where you could fall down at. But overall the map looks good and you must have put alot of time and effort into this map. And it helped alot. Overall: 4.5/5=-=-=-=-=-=-=-=~ Destroying AceWant another map reviewed? Want to become a reviewer? Message me.
i love it, youve got my dload
鲁克,我是你爸爸。你想去看电影The Cutting EdgeI've been part of the Bungie Conspiracy since Halo: CE...and I still blame Stosh.
This is a really creative level because of the design use of the small enclosed space. I didn't even know it was possible to use the space you made this map on, and I give you props for the idea.Gameplay, it works but It's nothing revolutionary, which is why overall I give you 4 of JB's food nipples out of 5. ;-)
This file is not part of any known file set.
© 2017 Bungie, Inc. All rights reserved.


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Gmail users are sucking up storage space faster than Google can add it.
Google said today it's speeding up the rate at which it adds storage space for Gmail due to the increased storage requirements for attachments such as photos.
"A few of you are using Gmail so much that you're running out of space, so to make good on our promise, today we're announcing we are speeding up our counter and giving out more free storage," wrote Rob Siemborski, a Google engineer on the Gmail blog.
This morning, the counter on the Gmail login page stood at more than 2,935MB, or about 2.9G bytes, of storage, and was rising - but the counter is an illustration rather than a hard limit.
Google started gradually increasing Gmail storage in April 2005 when the service turned one year old. Google's Gmail gained immediately popularity when it launched in 2004, offering free accounts with 1GB of storage, but this year has been surpassed by its rivals.
Microsoft upped its free storage limit for its Windows Live Hotmail service to 5GB in August, and Yahoo started offered "unlimited" storage in May.
See also: The pros and cons of unlimited storage


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Artist description:
A drawing of a fantasy elf warrior I made on my laptop (laptop pad only)
Java Draw Created Jun 08, 2012 736 x 1024px Unless noted Copyright 2012 awesomepigman.
We encourage you to submit a comment and let the artist know what you think of this drawing. Please log in or join to post a comment.
Post a comment
what the actual hotdamn...... fuu this is amazing!! ! haha love this!! 5h's for sure =D
You drew this with your laptop touchpad? I had used my laptop touchpad before and it's hard to draw with it- this must have taken quite a bit of effort and patience! I love the fantasy elf warrior's clothing, hair, pose and face. 5/5 and favorites.
oooh nice shading :D
Very nice...the colors and details are so pretty. 5/5 I draw using my laptop's touch pad too. : )
very fine work!
Amazing! You are talented to use a laptop pad for this much detail. I can't even use mine to click things (opt for mouse everytime). It's a very creative drawing. 5H


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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Wednesday, September 20, 2017
Arthritis and Rheumatism
Ibuprofen and Edema
I am a 30 yr old female and have been taking 2400 mg of ibuprofen per day for the past 9 months for undiagnosed multiple joint pain and stiffness (possible RA). For the past 6 weeks I have noticed pitting edema in my legs. Some days are worse than others, but it`s there constantly. Is this something I should be woried about? Does ibuprofen cause this?
Fluid retention, which can cause pitting edema, is a common side effect of ibuprofen and all of the other NSAIDs, including the new selective COX2 inhibitors, such as Celebrex and Vioxx. It is not caused by other pain-relievers that lack anti-inflammatory activity, such as acetaminophen (Tylenol and other brands). Generally, you can determine if the use of ibuprofen is causing the fluid retention and leg edema by discontinuing the ibuprofen for a couple of days and seeing if the leg edema completely resolves. Usually pitting edema in the legs becomes most noticeable after standing for several hours and is at its lowest level when you wake up in the morning. For most patients, mild pitting edema is harmless, although some patients develop such severe pitting edema that the drugs that cause it have to be discontinued or the patient must be treated with a diuretic. Many of these patients had a problem with kidney function even before they started to take an NSAID or are taking more than one medication that can influence kidney function and fluid retention. For most patients, the fluid retention associated with NSAID use does not reflect anything to be worried about; however, in some patients NSAID use can cause high blood pressure and/or a considerable decrease in kidney function. For this reason, it would be advisable to have your blood pressure checked and for your physician to perform blood tests that will indicate your kidney function and serum albumin level and a urine examination (urinalysis) that will determine whether NSAID use is causing you to lose protein and/or blood cells in the urine. If these tests are normal and your leg edema is relatively mild it should be safe for you to continue to take ibuprofen. Wearing support hose and keeping your legs elevated, whenever possible, should decrease edema. If the lab tests and/or blood pressure are abnormal, your physician should consider reducing your dose of ibuprofen, check to see whether it may be interacting with other medications that you may be taking (including herbal preparations and other drugs that you may be buying as "health foods" or buying without a prescription), substituting a different form of therapy, or (if there is no evidence of decreased kidney function or kidney damage), adding a low dose of a diuretic to your treatment regimen.
Fred Finkelman, MD
Director, Division of Immunology
College of Medicine
University of Cincinnati


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John McCain is beatable, just as Bob Bennett was in Utah, as Arlen Specter was in Pennsylvania, as Blanche Lincoln was in Arkansas, you get the idea.This is the Year of Bye-Bye-Incumbent.
And who defines the corrupt DC establishment better than John Sidney McCain? That would be the very same J Sid who voted against Wall Street reform. [Note: Link to accompanying article is now broken] Yes, that corrupt DC establishment candidate:
In the Senate vote, four Republicans sided with the Democrats for approval: Susan Collins, Olympia Snowe, Charles Grassley and Scott Brown.
Now that we've established who the establishment is, we have to establish who isn't. Think... think... who could beat Gramm-pa (as in Phil) aka "The Fundamentals of the Economy are Strong" McCain?
Why, Rodney Glassman could. And who is this Rodney Glassman I speak of?
This comes via an e-mailed press release internal polling memo (please note, edited to correct). Consider it an introduction:
He can win based on his appeal as a candidate as well as polling data that has been done to date in Arizona that shows he can beat both Republican candidates. [...]
McCain is vulnerable as a majority of voters in Arizona dislike him, disapprove of the job he is doing as U.S. Senator, and are not inclined to vote to re-elect him. This provides an opportunity for Rodney Glassman to defeat the 28-year incumbent. [...]
Even if McCain can pull out a victory, this bodes well for Glassman's campaign prospects.
--Most incumbents who lose in the general election had previously faced a contentious primary election. The fact that McCain is going through a bruising primary that will likely remain close means he will come out of the primary with a fractured base, higher negatives, and a much smaller war chest than when he started. This is a formula for success for Rodney Glassman's campaign as a challenger to a long-time incumbent.
--McCain is under 50 percent in the polls on multiple measurements:
--McCain is under 50 percent in the horserace vote against J.D. Hayworth among Republican primary voters in three (3) separate surveys. [...]
McCain is already under 50 percent against Rodney Glassman in a general election match-up. --McCain draws 48% to 35% for Glassman in the DailyKos/Research 2000 poll conducted in April.
--The margin is similar in the PPP poll – 49% for McCain to 33% for Glassman.
Oh, and just for good measure, let's not forget the wealth of information that Cliff Schecter provided in his book The Real McCain. Let's not ignore J Sid's infamous temper. And don't get me started about his tasteless sense of humor [sic]. All these things work against him, and besides, they're just fun to reminisce about. Oh, but I digress...
As for J.D. Hayworth, here are a few noteworthy little tidbits:
Glassman will have an even better opportunity to pick up the seat for Democrats.
--Glassman already leads Hayworth in one poll and is tied with him in another.
--Glassman leads Hayworth 42% to 39% among likely voters in the PPP poll done in late April.
--Glassman is statistically tied with Hayworth – 42% for Glassman to 43% for Hayworth – in the DailyKos/Research 2000 poll.
--Hayworth is deeply unpopular.
--According to the PPP poll, half of general election voters currently have an unfavorable opinion of Hayworth and more than twice as many dislike him as like him (23% favorable, 50% unfavorable).
Let's not forget - Hayworth was named one of the most corrupt members of Congress by an independent watchdog group and lost his Congressional seat in 2006 in large part due to his corrupt record and his dealings with convicted lobbyist Jack Abramoff.
One additional point from the memo: Glassman is fairly popular with general election voters in Arizona.
And there you have it. If you hadn't been aware of Rodney Glassman, you are now. McCain and Hayworth must be defeated. That's a given.


text: Josh Herrin Looking For Better Results On Home Turf Andrea Wilson | April 11, 2014 PHOTOGRAPHY BY ANDREA WILSONAUSTIN, TX, APR. 11 – If you're reigning AMA Superbike Champion Josh Herrin and you've stepped into the deep end – a.k.a. the Moto2 class in the World Championship – coming home to the U. S. of A for the Grand Prix of the Americas is a nice boost. Especially after a disastrous race debut at Qatar that ended as soon as it started after he got caught up in a first-lap crash."It was pretty tough just because qualifying definitely didn't go how we wanted," Herrin said looking back at Qatar. "We were 27th on the grid, which was the furthest I've ever been back on the grid so it was pretty hard to take in. But in the race we got up to 14th on the first lap and before I knew it I was sliding on asphalt. So I'm happy to come back to the United States and just put that race behind me and hopefully leave here with a lot better result for sure."Not only is it nice to be on home turf, but the Air Asia Caterham rider also got his first taste of a MotoGP pre-race press conference, sharing the stage with fellow Americans Nicky Hayden and Colin Edwards. And, of course, some other guys you may have heard of -Valentino Rossi and Marc Marquez."To be honest with you I never should be up here with these guys. It's quite an honor to be up here with such great riders," said Herrin. "Coming to racing Moto2 as the only American is really exciting and also to be able to come and do it in front of my home crowd is huge deal for me. I'm really excited to just get the weekend over with actually because Qatar didn't go as we wanted it to. And we're just hoping for a better result and just to enjoy the weekend really. I'm excited to be here, like I said. CoTA's [Circuit of The Americas] treated me really well and given us a lot of passes for my friends and family to come out. Just hopefully we can put on a good show for them."Moto2 is arguably one of the toughest championships in the world. It's a highly competitive class with a field that often times has more than a dozen riders within a second of the leader. And Herrin is adjusting."It's a lot tougher than I thought it was going to be to be honest with you," Herrin said. "It's basically the very best person I've ever rode with in the AMA [Superbike] but there's 40 of them. It makes it really hard. You really have to be mentally strong. That's the main thing that I've found out because riding around behind 20th place isn't easy when you've come from being in top five all the time for the past 10 years. That's been the hardest thing for me is in testing and even throughout the race weekend, is to be so far back."In spite of his struggles early on, Herrin is still positive and is looking to keep progressing."But the times are close -18th place in Free Practice 3 was under one second. So you just always have to think about that and I just have to remember it's my first year. A lot of these guys I've been watching race since I was a little especially guys like Tom Luthi and stuff. So I respect a lot of them. And they are definitely really fast." Andrea Wilson | Associate Editor / Website CoordinatorAndrea has been shooting everything from flat track to road racing in her job as a professional freelance photographer, but she's made the move to a full-time staff position at Cycle News where her love of all things motorcycling will translate well. Wilson has proven her worth as more than a photographer as she migrates to the written word with everything from race coverage to interviews. Comments


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Toremifene With or Without Atamestane in Treating Postmenopausal Women With Metastatic Breast Cancer
- Full Text View
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Toremifene may fight breast cancer by blocking the uptake of estrogen by the tumor cells. Atamestane may fight breast cancer by blocking the production of estrogen. It is not yet known if toremifene is more effective with or without atamestane.
PURPOSE: Randomized phase III trial to compare the effectiveness of toremifene with or without atamestane in treating postmenopausal women who have metastatic breast cancer.
|Breast Cancer
|Drug: atamestane Drug: toremifene
|Phase 3
|Study Type:
|Study Design:
|Primary Purpose: Treatment
|Official Title:
|Phase III Study of Atamestane Plus Toremifene in Metastatic Breast Cancer
|Study Start Date:
|October 2000
|Study Completion Date:
|May 2001
|Primary Completion Date:
|May 2001 (Final data collection date for primary outcome measure)
OBJECTIVES: I. Compare the time to progression in postmenopausal women with metastatic breast cancer treated with toremifene with or without atamestane. II. Compare the response rate, overall survival, duration of response, and time to treatment failure in patients treated with these regimens. III. Compare the safety profile of these regimens in this patient population.
OUTLINE: This is a randomized, double-blind, placebo-controlled, multicenter study. Patients are stratified according to study center. Patients are randomized to one of two treatment arms. Arm I: Patients receive oral toremifene daily and oral atamestane twice daily. Arm II: Patients receive oral toremifene as in arm I and an oral placebo twice daily. Treatment continues for 12-30 months in the absence of disease progression or unacceptable toxicity. Patients are followed every 12 weeks for survival.
PROJECTED ACCRUAL: A total of 594 patients (297 per treatment arm) will be accrued for this study within 18 months.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
DISEASE CHARACTERISTICS: Histologically confirmed metastatic breast cancer Bidimensionally measurable disease Lesion at least 2 cm in at least 1 diameter No failure with prior adjuvant antiestrogens within the first 12 months of treatment No progression of disease during therapy with prior aromatase inhibitors or selective estrogen receptor modulators (SERMs) (including SERMs for prevention of osteoporosis) No history of known central nervous system (CNS) metastases No bone metastases as only tumor manifestation Hormone receptor status: Estrogen receptor and/or progesterone receptor positive
PATIENT CHARACTERISTICS: Age: 18 and over Sex: Female Menopausal status: Postmenopausal Performance status: ECOG 0-1 Life expectancy: At least 12 weeks Hematopoietic: Hemoglobin at least 9 g/dL Platelet count at least 100,000/mm3 WBC at least 2,000/mm3 Hepatic: AST and ALT no greater than 2.5 times upper limit of normal (ULN) Bilirubin no greater than 2.5 times ULN Renal: Creatinine no greater than 2.0 mg/dL Other: No significant neurological dysfunction including seizures or clinical signs of other significant neurological diseases No other active malignancy within the past 5 years except basal cell skin cancer or carcinoma in situ of the cervix No contraindication to toremifene or its excipients or any of the excipients in atamestane Not pregnant or nursing
PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: No prior cytotoxic chemotherapy for metastatic disease At least 6 months since prior adjuvant chemotherapy No concurrent chemotherapy Endocrine therapy: See Disease Characteristics No prior hormonal therapy for metastatic disease At least 12 months since prior adjuvant antiestrogens No concurrent SERMs or estrogenic or androgenic hormones No other concurrent aromatase inhibitors Radiotherapy: No concurrent radiotherapy except for palliation for bone metastases Surgery: Not specified Other: No prior enrollment in this study At least 30 days since prior investigational drugs No other concurrent investigational drugs Concurrent bisphosphonates for bone metastases allowed
Please refer to this study by its ClinicalTrials.gov identifier: NCT00010322
|United States, New York
|Millennix Inc.
|Purchase, New York, United States, 10577
|Study Chair:
|Peter Langecker, MD, PhD
|Intarcia Therapeutics
|Responsible Party:
|Intarcia Therapeutics
|ClinicalTrials.gov Identifier:
|NCT00010322 History of Changes
|Other Study ID Numbers:
|Study First Received:
|February 2, 2001
|Last Updated:
|March 24, 2014
Keywords provided by Intarcia Therapeutics:
stage IV breast cancer
recurrent breast cancer
Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Antineoplastic Agents, Hormonal
Antineoplastic Agents
Selective Estrogen Receptor Modulators
Estrogen Receptor Modulators
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Bone Density Conservation Agents
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on September 20, 2017


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Nutter Butter Truffles Recipe
- 1 package (1 pound) Nutter Butter sandwich cookies
- 1 package (8 ounces) cream cheese, softened
- 8 ounces milk chocolate candy coating, melted
- 8 ounces white candy coating, melted
- 3 ounces bittersweet chocolate, melted
- 1. Place cookies in a food processor; cover and process until finely crushed. Add cream cheese; process until blended. Roll into 1-in. balls.
- 2. Dip half of the balls in milk chocolate, allowing excess to drip off. Place on waxed paper. Repeat with remaining balls and white coating. Drizzle bittersweet chocolate over truffles. Let stand until set. Store in an airtight container in the refrigerator. Yield: 4 dozen.
Nutritional Facts
1 truffle: 120 calories, 7g fat (4g saturated fat), 5mg cholesterol, 49mg sodium, 14g carbohydrate (10g sugars, 0 fiber), 1g protein.
Reviews for Nutter Butter Truffles
Average Rating
"Can anything be substituted for the cream cheese? I can't tolerate it ;-("
"I noticed these didn't have much peanut butter taste. I agree that I may try to add some peanut butter."
"The thing we like about Nutter Butters is the peanut butter. Way too much cream cheese that the peanut butter flavor is lost. I would suggest cutting back on the cream cheese to half a brick or doing half the cream cheese and adding peanut butter to get back some of the peanut butter flavor. I haven't tried what I'm suggesting but I believe it would help if you like the peanut butter flavor."
"These are so yummy & absolutely easy to make."
"This was a big hit!"


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Class of 2012 – Be Heard on SoJO
Early Congratulations to all who are a part of the graduating Class of 2012. As your big day approaches, we here at SoJO would like to hear from you with "shout-outs" to be played during the final stretch of your school career.
Feel free to call SoJO 104.9 and get a message recorded for your school and your friends. We will be looking for your calls throughout the day (especially in the morning with Tom Morgan, and during the SoJO 7@7 Countdown). Consider this your"15 seconds of fame" to get your message and your school out there. So long as you are graduating, it does not matter what level of school we are talking – middle school, high school, college, whatever!
Remember the number here is 1-800-586-1049. We'll be waiting for your call and your "shout-out"!


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Take in the views from a garden and make use of amenities such as tour/ticket assistance.. Free self parking is available onsite.. A complimentary full breakfast is included.. With a stay at Y Gelli Bed & Breakfast in Llanfairfechan, you'll be within the vicinity of Beaumaris Castle and Penrhyn Castle. This bed & breakfast is within the region of Bangor University and Conwy Castle.. Make yourself at home in one of the 3 guestrooms featuring DVD players and flat-screen televisions. Digital television is provided for your entertainment. Conveniences include coffee/tea makers and irons/ironing boards.
Photos Of
Room facilities


text: I've always been really fond of canaries. I'm not very much a bird person, though. I'm thinking more about it though...Sapphira passed away last year, and Aidan's getting older, and all I have are the snakes and him and Milo, really. We live with lots of other pets, but they're not "mine" really. I said no more small animals after these guys are gone, butttttt I waaaaant. I just don't know all that much about canary care. Are they messy like other, larger birds? Are they very tame, do they like attention and affection? Can you leave them, say, for a weekend with lights on a timer and a food dispenser? Do they poop all over the house if you let them out? Are they trainable at all? There are a lot of varieties, too...my main attraction to them are their songs. Do the pretty orangey and yellow ones sing? I think the ones bred for their songs are the sort of mottled greenish yellow ones, is that true? *sigh* maybe I'll just buy a canary songs CD


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Going up
Taylor Swift At first, we were blind to her vampy 50s starlet transformation. But now we see.
Willem Dafoe Still got it. Oh yes. See Prada ads and the latest Another Man cover for evidence.
Geisha slides Next season footwear terminology, coined by Vogue editor Alexandra Shulman on Twitter for the new chunky-chic mule.
Florence does boy-girl chic Now that we're loving the chic up-do in the Sweet Nothing vid, is it OK to say we were a bit over the witchy hair?
Going down
Clutch bags with rent-cheque price tags Get to Coast. Quick. This gold deco Nancy is a Lanvin-alike steal for just £70.
'Fabulous' The fashion compliments du jour come from the Diana Vreeland doc, The Eye Has To Travel. We're looking for bite, pep and pizzazz.
Taking your eye off the sports kit ball K Pop superstar G-Dragon styles his Chanel tennis racket with matching ball and sweatbands. Talk about intimidating your opponent.
The Downton lady look It's all about Maid Anna this season.


text: In 2006, I went to the VA hospital in Fargo, ND to have my disability re-evaluated on my left knee. The VA deemed it to be 10% originally. My range of motion was decreasing and I was having more problems with it locking. My appointment for left knee issues was not handled by an orthopedic surgeon, but rather a Physicians Assistant who literally followed a flow chart out of a book. When it came to range of motion, he physically pulled my leg back as far as he could and when it would not go any further, he leaned into it to hold it in place. I was found to still be at 10%. I am trying to get a new appointment to re-evaluate it again. Is there any regulation or directive in place that would allow me to have this particular exam done by an orthopedic surgeon?


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Republicans denounced the Obama administration's challenge of Arizona's new immigration law Tuesday, a fresh sign they may try to paint Democrats this fall as soft on illegal border crossings.Read More »
McCain breaks away as critical support eludes Hayworth
Six months of trying to outflank Sen. John McCain from the right produced less support, less money, fewer endorsements and lower poll numbers than J.D. Hayworth and his dedicated followers had anticipated.Read More »
Defining 'border security'
You wouldn't know it from the public debate, but the U.S.-Mexico border is more fortified now than it was even five years ago. Far more agents patrol it, more fences, barriers and technology protect it and taxpayers are spending billions more to reinforce it.Read More »
Mexico's Calderon criticizes state immigration law
Mexican President Felipe Calderon took his opposition to a new Arizona immigration law to Congress Thursday, saying it "ignores a reality that cannot be erased by decree."Read More »
Arizona pushes Congress into immigration minefield
Backed into a corner by Arizona's tough new immigration law, Democrats and Republicans alike find themselves grappling with a volatile issue neither party wanted to fight over just before important midterm congressional elections.Read More »


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Private school vs state school - the two tribes(98 Posts)
I have been walking DCs to their (state) junior school and have noticed a marked difference in the two tribes on either side of the road (girls' independent and prep school on one side, state junior and comprehensive secondary on the other).
These two streams of humanity mark themselves out in the following way:
1. Private school kids hop out of SUVs, whereas there are scooters, bicycles and shanks' pony for the state school kids.
2. No dads or grannies taking private school kids to school - it's almost all mums and nannies.
3. Private school kids look like pack-horses with sports kit with hockey stick, racquet etc., school book bag and occasionally a monstrous musical instrument (sometimes several times the size of the child) whereas the state school kids carry a book bag or nothing at all.
4. Private school girls' skirts are so short they would not be acceptable in the state school (which is odd - there are no boys to impress at the private schools anyway - maybe a girly competitive thing?).
5. Immaculately coiffed hair is de rigeur for the girls' schools, although state school kids have more adventurous hairstyles (e.g. corn-braids, spiky hair).
6. Private school girls are much more diverse in height (some very little, some very tall), but state school kids seem to cluster around the mean.
SC - hadn't noticed this was old - hey ho - mild diversion whilst cooking dinner!
having been at private, lots of friends kids are private, my kids are state
I thought the OP was really funny
inaccurate but funnyte
OP I'm surprised any parents at all are taking their DC to secondary school. Round here, state or private, they make their own way by train, bus or on foot.
Your number 3 on the list is also surprising. Round here the comps also provide loads of chances for people to play monstrous musical instruments and different sports. I'd not be keen on any school that had pupils who couldn't be bothered to play a range of sport and instruments, or read a lot of books. Walking like packhorses from the SUVs they've just hopped out of into the school grounds can't be too arduous.
I drive mine to school - out of catchment, buses at wrong times and cost lots, no trains, 4.5 miles away.
they get the bus home
You obviously have better public transport than us Racing, the earliest bus from our village is 10.15am.There are school buses but I work next door to the school so drive.
Not much difference in terms of smartness here , if anything I think the local state school is neater ,skirts tend to be shorter but a more flattering style than the independent . There are a lot more designer labels on display at state though , practically all the girls seem to have Jack Wills and Abercrombie sweatshirts on to walk to school.
It does puzzle me that the teens have such small bags though, even the 15 and 16 year olds seem to have a small drawstring or just a handbag . Do they do all their homework online? The independents seem have huge rucksacks full of books , and I know because ds 1 was at the I dependent that they do store stuff at school so don't need to bring everything home, it is homework.
State high performing by the way so not implying that they don't do homework or not work as hard etc, just puzzled.
A large heavy duty bag stuffed with books is part of my DCs standard daily 'uniform' at their indie. Most days they have extra luggage like sports bag and instrument case. Less books I can understand but why arent the state kids laden down with sports bags???
I don't have a SUV but I accept that many others do, probably so that they can transport all the kids plus the above mentioned 'luggage'.
Fashion? No difference. Girls are girls regardless of type of school. And since when girls let limited funds determine what clothes to buy?
Cor OP, chip on shoulder much?!
Message deleted by Mumsnet for breaking our Talk Guidelines. Replies may also be deleted.
That OP was a bit bitter wasn't it? I have two at private, one at state. They all have nice hair . Yes, the private school kids have loads of kit - that's because they all learn an instrument and all play loads of sport. They work hard at both, its not a fashion statement. State school dd also learns an instrument but the only music lessons they do at her school are recorder and piano - the recorder fits in her book bag and they don't expect her to carry the piano around .
You've generalised, so so shall I. None of the state school comprehensive kids wear coats here as they don't have pegs, if they wear coats they have to carry them around all day. When they tried to introduce lockers, stuff kept getting vandalised and nicked. I think I'll take the extra violin cases.
Sorry OP - your "observations" are not typical of the independents I know and use. The everyone drives an SUV stuff is nonsense and as far only mummies and nannies taking the kids to school - really? Are you being truthful here? Do you live in Chelsea? Are they all the children of oligarchs?
The only things I would agree with is that more children (at Junior level anyway) are driven to school, (as the privates draw their custom from a 10/20 mile or so radius - not exactly walk-able) and yes - they certainly do carry more kit.
I've just realised I posted on this thread 2 years ago under a previous name!
It still pisses me off a bit though.
OP, not in London. Not at all. Somewhere else I dunno.
The height comment is though.
Think it depends on the private school- DS is not heavily laden at prep school - ...1) sports kit (clothes, boots, sticks etc) for whole term is taken in large holdall on first day of term, and I don't see it again til last day of term - it's all labelled in the right places and sports clothes laundered and sorted weekly by school laundry (which is great)
2) prep (i.e. homework) is done/supervised daily in school after lessons - which is why he has a longer day so not a lot of folders come home.
Rest is musical instruments to and fro and rucksack with a couple of books and pencil case.
Sorry - SUVs are standard and Range Rovers even more so.. but this is a country prep
OP My post was edited somehow I meant your height comment was very very silly and flippant. Really.
yes height comment is ridiculous...didn't bother to take bait on that one
I second the kit. My 5 yo DS looks like he's going on an expedition on a Monday. I just hang bags off him and push him through the gate in the hope his own momentum will get him in the class before he topples over.
On the skirt front our girls grammar school has to be the worst offender. But it was the same when I went there 25 years ago. We had GIANT perms though where now there is ironed barnets.
No, OP, everyone knows that state school kids and their parents are clad from head to toe in designer gear, drive 4by4s and are tanned from their regular long haul holidays. Oh and are massively fat because they spend all their time watching Sky. While private school kids and parents wqlk 10 miles to school because their beaten up old Volvo has broken down, wear second hand uniform and clothes from charity shops and are still recovering from the trench foot they got on their camping holiday in Cornwall.
The idea of it being "two tribes" is an exaggeration anyway, which one only finds on places like... predominantly middle-class parenting chat fora It's easy to get the impression that parents are divided 50-50, into those who have made one "choice" and those who have made another. In reality, an very small percentage of pupils go to private schools (about 7% nationally, and as low as under 1% in some towns). It isn't even an option for the vast majority of parents. For most normal, working, middle-class people.
To put it into context, 7% is about the proportion of the population which is left-handed
Heights... varies. My daughter at North London Collegiate (academic private, lots of Indian and Jewish girls i.e. fairly short) who did loads of sport said in lacrosse when they played posh country private schools the girls were all very tall and blonde. When they played largely Afro Caribbean/African origina state school pupils at netball they could be really tall (good for goal shooting). I assume Somali girls are tall but not sure how much they pay netball if they have to be covered etc.
I do agree that you can classify people. You can do it anywhere and amongst adults too. People seem to like their badges of class or group, their public affirmation that they belong to XYZ. In a good few private schools it is a bit common and nouveau riche to drive a ridiculously expensive car. That Perry artist did a good 3 part TV series on class and in his upper class programme the last one the family had a very old car as a matter of course. The middle class trying to look richer than they are lot in their 4 bed new estate homes had the trying to show off kind of cars.
Agree with the being weighed down point. Our 5 children (yes I pay 5 sets of school fees or did and yes women can earn enough to fund that alone plus other costs if they pick careers wisely) are pretty musical (3 won music scholarships). The biggest instruments have been french horn and 'cello and loads of sports bags. I could hardly pick up the bag of one this morning but that's because he obviously is carrying around more than he needs.
Where did you say your DD went to school again, Xenia?
Xenia, you must be a magic circle law firm partner or hedge fund manager ....but no need to tell us...keep them guessing!
This is a pretty narrow view. In my town the 2 state schools' kids look like the ones you describe from your private school- the boys and girls here play hockey, learn musical instruments, have loads of kit, etc etc.
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It's all up to Kobe Bryant now.
Bryant has been fully cleared to resume all basketball activities, the Lakers have announced. Bryant has not played since rupturing his left Achilles tendon in a game against the Warriors on April 12.
Whenever Bryant plays in a game is up to him, according to Bleacher Report's Kevin Ding. The Dec. 6 game against the Kings has been floated as a possibility, but it could be earlier or later depending on how Bryant feels. He was cleared for practice Saturday but did not take part in contact drills or practice against a defender.
Bryant still needs to test his ankle joint, which was immobilized for months while the tendon healed. But do not expect an extended Derrick Rose-type absence. Bryant has said he is shooting for an early-December return, and this recent development means that timetable could still be in effect.
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Jennifer Aniston tired of pregnancy questions
Jennifer Aniston insists you can't think of starting a family like creating the perfect meal at a fast food restaurant.
The 44-year-old star, who is engaged to actor Justin Theroux, is constantly asked when she plans to have children.
Jennifer has been the subject of tabloid fodder since her five-year marriage to Brad Pitt imploded in 2005 and he began seeing partner Angelina Jolie. The couple have a total of six children, leaving many to wonder when Jennifer would become a mother.
But the actress insists the constant peppering about getting pregnant only annoys her, particularly when reporters try to link her personal live to her film roles.
"Something about family and trying to relate it to the movie with, 'Oh, if I was to have a child how many kids do I want?' And 'do I want a boy or a girl?'" she confessed in an interview with ABC News are phrases which really get her in a ruffle.
She urges journalists to pose more thoughtful questions.
The star scoffed at the suggestion of plotting out parenthood.
"I didn't realise you could place orders, I honestly didn't realise it was like a drive-through, that you could talk to a little electronic voice," she mused.
Jennifer stars in new movie We're the Millers, in which she plays a stripper who pretends to be the mother of two kids.
The ploy is to help a drug dealer, played by Jason Sudeikis, smuggle a marijuana shipment over the Mexican border.
The actress admitted she had doubts about taking the part.
"I said yes thinking 'wouldn't that be great,' thinking, 'well, I've never played a stripper, at least not in film…' then this panic sets in three weeks, two weeks, one week before the actual day of shooting," she recalled.
She took on a strict exercise regime, working out an hour each day for six days a week.
"Honestly it was the craziest workout," she said. "My diet has always been pretty clean but I think I was super, super strict, especially in terms of, I'll usually cheat once or twice a week and I just kind of didn't."
© Cover Media


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Problem Management - Key Best Practices
The ITIL framework supplies an excellent relational model on how to manage Incidents, Problems and Changes. But this model becomes much more powerful when best practices are applied; such as planning and documenting Roles and Responsibilities, proper Operational Metrics and defined processes for Knowledge Management, Root Cause Analysis, ROI Calculation and Customer Satisfaction.
Provided by: NetworkD Topic: Mobility Date Added: Jun 2005 Format: PDF


text:
Facing TV Problems? Ask a TV Technician.
We use the TV remote to operate the TV. I believe we are using a direct coaxial cable to the TV buty I'm not sure.
There is no Cable box.
I just went to check and the TV is now working. Go figure.
Sorry the message was no signal though and yes the channel information was coming up.
There is an INPUT button on the remote.
If you could please let me know how to fix it if it happens again that would be great.


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There are a lot of celebrity car collections out there, but not all of them are selected to form the basis of an international arts exhibit glorifying some of the most beautiful automotive designs to ever grace the world's highways. Accomplished fashion designer Ralph Lauren's exquisitely curated automobile holdings were given this exclusive treatment by Les Arts Décoratifs museum in Paris, France, which this past summer hosted dozens of the most notable pieces in his formidable collection.
The four-month exhibition, dubbed "L'Art De L'Automobile" (The Art of the Automobile) made available to the public some of the rarest and important cars to have survived the past 100 years, with a reach that extended back to pre-World War II European masterpieces while also including several more modern supercars.


text:
Hello and welcome!
My name is Michael Curtis, I'm a recording artist/producer based out of Los Angeles, California. Thank you for checking out i_eminent, my music on Audiojungle!
In my portfolio you will find an array of musical pieces perfect for any project. I put up new songs often, so please check in regularly
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After covering a number of subjects, Syracuse basketball head coach Jim Boeheim was wrapping up and on his way out of his post game press conference following Syracuse's 57-55 win over Cincinnati.
Then inspiration hit and just like Columbo, he had one more thing to say.
As Syracuse continues the farewell tour of the Big East, Boeheim went back to the podium to get an opinion in on the Big East's scheduling practices.
While glancing in the direction of John Paquette, who is the Associate Commissioner of Communications for the Big East, Boeheim said this.
"It is ridiculous to play games like this Saturday and Monday. This is ridiculous. It's stupid. Cincinnati just played four games in eight days and now they are off nine days? We played four games in the league in ten days and now we're off for another week. It's ridiculous. This is not the right way to schedule. It shouldn't be like that. We're off all week then we have to play Saturday and Monday again. It's just stupid. Really stupid."
A glance at the Syracuse schedule shows that the Saturday-Monday scenario Boeheim loathes will come up again two more times.
On Saturday, February 2, Syracuse will travel to Pittsburgh for a noon game before hosting Notre Dame on Monday, Feb 4 at 7:00 p.m.
After five days off, Syracuse begins another busy stretch on Sunday, Feb 10 when they host St.John's, travel to Connecticut on Wednesday, Feb 13 then visit Seton Hall on February 16.
Syracuse then hosts Providence on Wednesday, Feb 20 and Georgetown on Saturday, Feb 23 at 4:00 p.m. before a quick turnaround game at Marquette on Feb 25 at 7:00 p.m.
The Orange get five days off before hosting Louisville on Saturday, March 2 at noon and DePaul on Wed, March 6 at 6:00 p.m.
Syracuse finishes the regular season at Georgetown on Saturday, March 9 at noon.
What do you think of the Syracuse schedule?
Does Boeheim have a point or is the Big East doing what it can with so many games to play?
How can the schedule be done better?
While we are at it, what is up with 11 a.m. start times in the Big East this season, like Syracuse has at Villanova on Saturday?
Drop below in the comments or send me an email.
Brent Axe
or post a comment below


text:
Child Line founder Esther Rantzen has launched a similar service for elderly people in distress; Silver Line is being piloted in Manchester and will go live across the rest of the UK in the coming year.
Northern Ireland hoped that the end of the Troubles in the Province would see a boom in tourism boom but despite an expensive advertising campaign the number of visitors to Northern Ireland has fallen.
Britain has gone coupon crazy; last year 60% of us used one and the boom is likely to continue as the hard pressed seek to cash in on bargains in tough economic times.
A disclaimer popping up on your Facebook urging you to post it on your page or risk losing copyright over any personal content is a hoax.
Mark Pearson, the man behind one of the UK's biggest online discount voucher companies, was a cash strapped twenty-something before having the idea that launched him onto the Sunday Times Rich List six years later what was the secret of his success?
A Continental style Christmas Market has become popular in many of our towns and cities; they look pretty but local traders find them less attractive.
Britain's first 'packaging free' grocery store has opened but is it such a good idea?


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Four Philadelphia pitchers combined for the 12th no-hitter in team history Monday as the Phillies shutout the Braves 7-0 in Atlanta.
It was the first combined no-hitter in the teams' history. Cole Hamels went the first six innings striking out seven and walking five. After that Jake Diekman, Ken Giles and Jonathan Papelbon each pitched one perfect inning to complete the gem.
The Braves have struggled mightily at the plate lately scoring only one run over the last three days.
Clayton Kershaw and Josh Beckett of the Dodgers and Tim Lincecum of the Giants each threw no-hitter earlier this year.


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Posted by Scott Barlow, Reflexion Networks
Intensifying concerns about data privacy are driving a broad range of governmental regulations that impose a new spectrum of requirements for businesses. Requirements vary by industry segment, such as healthcare and financial services, and even by location, as state legislation becomes more common. For example, all U.S. states with the exception of Alabama, Kentucky, New Mexico, and South Dakota have privacy and data breach notification laws; healthcare organizations are subject to HIPAA; brokerage firms must comply with FINRA; SOX affects all publicly-traded companies in the U.S.; and all financial institutions, such as banks, insurance companies, securities firms, consumer finance companies, and investment advisors must comply with GLBA — just to mention a few.
While government regulation is often thought of as primarily affecting large enterprises, small and midsize businesses are increasingly affected. For example, the Massachusetts Data Privacy laws (CMR 201) apply to any company that collects personally identifying information for any Massachusetts citizen, regardless of the company's location. Many businesses don't have the resources to track these regulations and may turn to their traditional "trusted IT advisor" for advice on compliance. However, while solution providers are quite skilled in the application of technology to solve business problems, they may not have the necessary domain knowledge when it comes to the specific requirements of pertinent legislation.
This challenge creates an opportunity for solution providers to expand their value-add as their client's "trusted compliance advisor." Evolving into this role will require study and ongoing tracking of new requirements that are formalized into law, but the financial and customer retention rewards for such expertise could make it well worthwhile. Compliance requires a blend of trained people, sound processes and appropriate technology. Once requirements are understood, as they relate to a specific customer, solution providers will have all of the skills necessary to deploy the appropriate tools, which typically include email security, email archiving, and email encryption. Email encryption solutions, for example, can be used to automatically encrypt outbound messages that contain patient data, social security and credit card numbers, and other protected consumer information. While email encryption alone does not address the entire issue of data leakage, it does protect a crucial threat vector.
Email archiving addresses a second dimension of compliance. The Federal Rules of Civil Procedure (the legal rules governing civil suits) require litigants to provide pertinent electronically stored information (ESI) during the discovery phase of a trial. Without an archiving solution, compliance may be extremely difficult and costly. An inability to provide information may create an appearance of guilt, and failure to meet specified deadlines may result in stiff penalties. Firms that may be the subject of civil litigation, such as professional services firms, should have a solution in place as insurance to minimize this risk, respond to discovery requests in a timely manner, and allow legal counsel ample time to prepare a defense.
To address the compliance needs of their customers, solution providers should look for integrated tools that can be easily deployed and centrally managed, in order to reduce their costs. Hosted solutions typically provide rapid deployment and avoid the up-front outlays for on-premises solutions.
End-user education and effective internal policies and procedures are also essential elements of any effective compliance program. For example, if employees do not know what the requirements are, they may not be aware of the risks to which they are exposing their employers. Similarly, a lost laptop trumps the effectiveness of any email encryption system. Once solution providers understand the requirements of pertinent legislation, they will be in an excellent position to provide the necessary training and process counseling in conjunction with pertinent technology.
Of course, the flip side of opportunity is risk. The risk here is that in today's business environment, without grounding in specific compliance requirements, solution providers run the risk of losing their claim to "trusted IT advisor" status. With this expertise, on the other hand, they can accelerate transitioning from selling products and services, to more effectively leveraging deployed services to help customers comply with state and federal legislation, and increase their revenue as a result of increasing operational efficiency.


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I've been putting raw organic honey on my face after washing it and leaving it on for about 10 minutes and it's been working wonders! I've been doing this for about 3 weeks now and I've seen major improvements. Honey mosturizes skin and can help with hyperpigmentation, it has natural antioxidants and other benefits that I cant recall off the top of my head.
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Laser Squad Nemesis
Review by pickled pizza
"Nice tactical combat from the likes of X-COM!"
This is a review about a tactical combat game, Laser Squad Nemesis, or LSN. LSN is a play by email (PBEM) game from the makers of X-COM. This is an excellent game as you will soon find out.
This is where LSN shines. There are three races, Laser Marines, Machina, and Spawn. There is a soon to be released fourth race, the greys. If you subscribe then you can send a challenge to anyone. If you don't subscribe then you can play 3 games against 'Bounty Hunters' that will help you get a feel for the game, but you can still be challenged by subscribers. The whole process of playing a game is this:
1. Initiate game
2. Deploy forces (each unit has a point value and you have limited points.)
3. Send orders
4. Watch what happens
5. Repeat 3-4 until you win or lose.
After you deploy you both make your moves at the same time, and send the orders. Next turn you watch what the outcome was of the previous orders and you make new orders on the current situation. It is kind of weird at first, but it's easy to get used to. If you liked X-COM then you'll probably love this. My only gripe about gameplay now is that the newest race, the Spawn (weird alien thingies) is a bit unbalanced. The success rate as playing as Marines vs. Spawn is a measly 33%. The spawn are super fast, have lots of cheap units, can reproduce by having a queen eat corpses and lay eggs, and are somewhat tough. It's a bit unbalanced, but you could just play people you know don't play Spawn. Since you PBEM you only send about 10-50kb files via email so you can play with dialup. This game is free up front but subscribers pay 40/year.
Well, granted, there isn't much of a story. Machina robots revolt against humans and the Laser Marines are formed, blah blah blah. But this is a multiplayer game and doesn't need a story to be fun.
Not much in the way of audio, just lasers firing and grenades exploding.
The graphics are slick in this game and are pretty good. The models look very good and assume firing poses and more. Buildings look OK, but there is repetition of tiles in some maps. The lasers and explosions look pretty good, explosions leaving behind smoke and destroying walls.
Tons and tons of replay value. There are lots of maps, but only two modes of gameplay: HQ and wipeout. The three races all demand different strategies. There are leagues and competitions to play in and medals to win. You can go to the forums they run and find opponents.
Reviewer's Rating: 4.5 - Outstanding
Originally Posted: 05/10/03, Updated 05/10/03
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Online sales on Cyber Monday increased by 16% to $2.29 billion compared to last year, according to Adobe's Digital Index 2013, and a record 18.3% of those sales came from mobile devices — a surge of 80% compared to last year.
Consumer shopping preferences continued to shift online with Cyber Monday being the fifth day in a row of record-breaking online sales. While "brick and click" retailers dominated Thanksgiving weekend sales, Internet retailers generated the most sales on Cyber Monday with a 42% share.
Adobe's online shopping data is based on the analysis of nearly 900 million visits to 2,000 retailers' websites on Cyber Monday and more than 3 billion visits since Thanksgiving Day. Total online sales for Cyber Monday came in just 1% above Adobe's prediction from Nov. 5. The data also showed that 70% of online sales with the top 500 U.S. retailers — taken from Internet Retailer's top 500 list — are generated by companies using Adobe Analytics, a key component of Adobe Marketing Cloud.
"Retailers earned 10% of their holiday sales in just the last five days, an increase of 26% year-over-year," said Tamara Gaffney, principal analyst, Adobe Digital Index.
Smartphones and tablets drove $419 million in online sales on Cyber Monday, a new record according to Adobe. Tablets generated the majority of mobile-driven sales at 12.7% of total online sales. iPad took the lion's share with 10.1% while Android based tablets generated $23 million or 1% of total sales. Alaska and Hawaii had the largest mobile sales revenue with 26.6% compared to the 18% national average.
Social media sites drove $148 million in online sales between Thanksgiving and Cyber Monday, a 2% share and flat compared to last year. Twitter's share grew most (up 24%) to 9% of total online sales. Pinterest also saw strong growth increasing its share of referral traffic by 17% year-over-year. Facebook drove 64% of all social media driven sales, an increase of 12%.
iPad continued to generate the most social media buzz of any tablet followed by the Samsung Galaxy tablet. PlayStation 4 was the leader in social media traffic on game consoles in the last five days.
Although retail promotions dramatically impacted Black Friday, pushing online sales up 39% year-over-year, Cyber Monday shopping patterns were consistent with previous years. Cyber Monday sales peaked between 8 and 9 p.m. EST with sales bringing in $150 million in one hour.