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Journal of Obesity
Volume 2011 (2011), Article ID 329038, 8 pages
Gene by Sex Interaction for Measures of Obesity in the Framingham Heart Study
1Duke Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA
2Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
3Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
Received 14 September 2010; Revised 17 November 2010; Accepted 22 November 2010
Academic Editor: Yvon Chagnon
Copyright © 2011 Ashlee M. Benjamin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Obesity is an increasingly prevalent and severe health concern with a substantial heritable component and marked sex differences. We sought to determine if the effect of genetic variants also differed by sex by performing a genome-wide association study modeling the effect of genotype-by-sex interaction on obesity phenotypes. Genotype data from individuals in the Framingham Heart Study Offspring cohort were analyzed across five exams. Although no variants showed genome-wide significant gene-by-sex interaction in any individual exam, four polymorphisms displayed a consistent BMI association (-values .00186 to .00010) across all five exams. These variants were clustered downstream of LYPLAL1, which encodes a lipase/esterase expressed in adipose tissue, a locus previously identified as having sex-specific effects on central obesity. Primary effects in males were in the opposite direction from females and were replicated in Framingham Generation 3. Our data support a sex-influenced association between genetic variation at the LYPLAL1 locus and obesity-related traits.
1. Introduction
Overweight and obesity present a major public health challenge in the developed world and are a primary focus of preventive healthcare. Rates of both overall adiposity, measured by body mass index (BMI), as well as central (intra-abdominal) adiposity, measured by waist circumference (WC) or waist to hip ratio (WHR) have been steadily rising during the past several decades, accompanied by increased rates of diabetes mellitus, cardiovascular disease, and other morbidities [1]. In the United States, regional, racial, and sex differences in adiposity have been noted, but the patterns are complex and changing over time [1]. According to U.S. national health survey data, men on average have had a higher BMI than women, but since the mid 1990s the average BMI in women has been higher than men [2]. Men also tend to have larger abdominal girth than women, and this disparity has persisted over time [3, 4].
Obesity is a heritable trait and recent genome-wide association studies have identified dozens of loci influencing measures of adiposity [5–8]. Sex differences in the heritability of obesity-related traits have been noted as well in several studies [9]. In addition, linkage analysis in both rodent models and humans have found evidence of sex-specific loci affecting obesity-related traits [10, 11]. Framingham Heart Study investigators found widespread evidence for sex-specific effects of genetic loci on body mass index, identifying several chromosomal regions with suggestive linkage to BMI in one sex, but not the other [11]. Indeed some effects were only seen in sex-stratified analyses and were not at all evident in the combined cohort of men and women. More recently, two genome-wide association study meta-analyses of WHR examined their top loci for sex differences and identified sex-specific effects for several loci [8, 12].
We sought evidence for significant differences in SNP effects on adiposity traits in men and women across the genome by carrying out a genome-wide association study modeling gene by sex interaction for WHR, WC, and BMI in the population-based Framingham Heart Study. Genome-wide association analysis of SNPs having main effects (as opposed to gene by sex interaction) on obesity were reported earlier in the Framingham Heart Study using 100 K SNPs, but gene by sex interactions were not considered at that time [13]. Subsequently, the full genotype data (>500 K SNPs) have been pooled with other studies and reported in large meta-analyses, which found evidence of gene by sex interaction for WHR but not BMI among the SNPs with main effects [5, 8].
2. Materials and Methods
2.1. Study Population
We conducted this research using data from the Framingham Heart Study, a population-based, longitudinal study of families living in the town of Framingham, Massachusetts collected over three-generations beginning in 1948. An overview of the study is provided at the dbGap website (http://www.ncbi.nlm.nih.gov/sites/entrez?db=gap) and detailed descriptions are available elsewhere [14, 15]. Briefly, the original study (Generation 1) enrolled 5209 individuals, primarily Caucasian, and it later added the offspring of the original cohort (Generation 2), and the grandchildren (Generation 3) of the original cohort. Primary analyses were carried out using data from the five first exams of subjects in Generation 2, collected between 1971 and 1994. Obesity-related traits evaluated in this study included BMI, measured at exams 1, 2, 3, 4, and 5, WHR, measured at exams 4 and 5, and WC measured at exams 4 and 5. We limited our analyses to these exams due to a drop in sample size at subsequent exams. Replication of genome wide association study (GWAS) results was sought in subjects from Generation 3 (data collected in 2002–2005).
Individuals with diabetes (, and 136 for generation 2 exams 1, 2, 3, 4, 5 and generation 3 exam 1, resp.) or thyroid disorder (, and 72 for generation 2 exams 1, 2, 3, 4, 5 and generation 3 exam 1, resp.) were removed because these diseases have an effect on both BMI and fat distribution. The data were further trimmed, excluding individuals with outlier trait values determined by taking the mean of the phenotype (independently for each exam and each sex) and adding/subtracting three standard deviations. Removal of outlier values in the BMI GWAS data was performed with weight, height, and BMI. WC and hip circumference (HC) outliers were also eliminated in the waist phenotype GWAS. Finally, we restricted our analysis to premenopausal women and individuals under the age of 50 to enhance differences related to estrogen-mediated gene by sex interaction and to reduce as much as possible the age-related differences in association that may occur across exams. The total sample sizes for the BMI GWAS after genotype quality control and trait outlier removal were 3150, 1991, 1630, 1330, 990, and 2872 for generation 2 exams 1, 2, 3, 4, 5, and generation 3 exam 1, respectively. The sample sizes for the waist phenotype GWAS were 1330, 984, and 2872 for generation 2 exams 4, 5 and generation 3 exam 1, respectively.
2.2. Genotype Data and Quality Control
Genome-wide genotypes and detailed clinical data have been made accessible to the research community through the SHARe project (SNP-Health Association Resource). The study protocol was approved by Duke University's Institutional Review Board and the Framingham SHARe Data Access Committee. The unfiltered genotype data contained 9215 individuals (all generations) genotyped for 549782 SNPs. This included 500568 SNPs from the Affymetrix 500 K mapping array and 49214 SNPs from the Affymetrix 50 K supplemental array (Affymetrix, Santa Clara, CA, USA). We used the toolset PLINK [16] to perform quality control. Individuals were excluded if genotyping rates were less than 97%. Markers were excluded if genotyping rates were less than 97%, minor allele frequencies were less than 0.05, or if Hardy-Weinberg -values were less than .001. All SNP exclusions were made sequentially in the preceding order. Using this filtered data, we checked for Mendel errors using a 5% cutoff per family, and a 10% cutoff per SNP (as defined in PLINK), but none were detected. Individuals were also excluded if the predicted sex based on X-chromosome genotypes did not match the recorded sex. Pairwise identity-by-descent measures were calculated to detect replicated samples and unknown interfamilial relationships. We detected 4 identical twins and randomly selected one member of each pair for the analytic sample. After quality controls, the remaining sample consisted of genotype data on 360811 SNPs, attaining a genotyping rate of 99.5%.
2.3. Statistical Analyses
Analysis of WHR and WC were based on data obtained at exam 4 () and exam 5 () of subjects from Generation 2. The gene by sex GWAS was run on data from each exam separately. We ran the full model for both WHR and WC regressed on BMI, age, age-squared, genotype, sex, and the genotype-by-sex cross product. BMI was available at all exams, with adequate sample sizes on the first five exams. Five separate GWAS were run using the full model of BMI regressed on age, age-squared, genotype, sex, and the genotype-by-sex cross product—one each for exams 1, 2, 3, 4, and 5 of Generation 2. SNPs were evaluated for associations in an additive genetic model. A main effect GWAS was also run for BMI across the five exams, using the model specifications above without the cross product term. Sex-specific associations were tested using the full model of BMI regressed on age, age-squared, and genotype on each sex. To account for relatedness, we used generalized estimating equations while accounting for sibling correlation in the Yags package [17] of the statistical language. The -values of the covariates were obtained via the Wald test using robust standard errors. The Framingham population has been studied extensively, and evidence for considerable population stratification has not been detected. To test this assumption, we estimated the inflation factor by dividing the median of the observed χ2 statistics for each GWAS, by the expected median in the absence of stratification (0.456) [18, 19]. Also, adjusted for population stratification with the scores of the first 10 principal components, computed with Eigenstrat [20]. We defined genome-wide significance using a Bonferroni cutoff of , which corrects for 360811 tests.
Following genome-wide analysis, we annotated results using the WGAViewer package [21], Ensembl [22], and the UCSC genome browser. We generated plots using the Gap package [23] of the statistical language and Haploview software [24].
To enrich for true positive associations, we took a strategy whereby associations that appeared in all exams were considered to have a higher likelihood of being true associations. We expected earlier exams to have greater power due to larger sample sizes, but other factors, including decreased heritability with age [11] may affect the results as well. This strategy required us to make some decisions about what cutoff to use when comparing results across exams. We took the consensus across exams of the top most significant 10, 100, 1000, and 10000 hits and found 0, 0, 4, and 105 SNPs, respectively, and focused on the four SNPs from the top 1000 consensus further.
3. Results
Characteristics of the subjects from Generations 2 and 3 of the Framingham Study used in the current analyses are presented in Table 1, broken down by exam. For each exam, we restricted our analyses to men and women <50 years of age, resulting in a decrease in sample size over time, above and beyond the loss due to death or nonparticipation.
3.1. Genome-Wide Association Analysis of Gene by Sex Interaction for WHR and WC and BMI
None of the gene-by-sex interaction GWAS revealed genome-wide significant loci. For BMI we noted marked heterogeneity in quantile-quantile (QQ) plots between exams (Figure 1), which does not appear to be a function of sample size (which decreases with exam). There is also some evidence of inflation in the QQ plots, which was not alleviated after controlling for population stratification. In sex-stratified analysis, the inflation appeared to be restricted to men. The top 1000 hits from each exam for each trait (ordered by the -value of the gene by sex interaction term) were extracted (Supplementary Tables S1, S2, and S3 available online on http://dx.doi.org/10.1155/2011/329038), and the intersection of those datasets was sought for each trait.
For WHR, we identified 43 SNPs (28 unique loci) and for WC, we identified 43 SNPs (27 unique loci) appearing among the top 1000 in both exams 4 and 5 (Tables S2 and S3). When examining loci across these two traits, SNPs near SPOCK3, OSTF1, RAB31, and RPF1 appear in the top 1000 consensus for WC and WHR. SPOCK3 stands out as appearing among the top 100 hits across both exams 4 and 5 for WC ( and ) and WHR ( and ).
For BMI, only four SNPs appeared among the top 1000 hits in all five exams. All four SNPs localized to the same linkage disequilibrium block on chromosome 1, ~100 kb downstream of LYPLAL1. Supplementary Table S3.6 shows the location, minor allele frequency, P values, and rank of each SNP by sex interaction by exam. We were most intrigued by these findings as the LYPLAL1 locus has been reported as a sex-specific locus affecting central adiposity in two prior genome-wide association meta-analyses [8, 12]. The extent of linkage disequilibrium (LD) surrounding the associated SNPs in the region of LYPLAL1 was determined in the Hap Map phase 3 CEU population by identifying the farthest SNP away in each direction that had for each of the four SNPs. The LD block extends over 330 kb from position 217,321,833 to 217,655,426, and encompasses the LYPLAL1 gene (Figure 2). The block does not include the SNPs from Lindgren et al. [12] or Heid et al. [8], which are in moderate linkage disequilibrium with each other and located an additional 55 kb and 258 kb downstream of LYPLAL1, respectively.
3.2. Replication of LYPLAL1 SNP Association with BMI in Framingham Generation 3 Subjects
We next sought to replicate the observed association in subjects from Generation 3 of the Framingham Study. Again, we restricted our analyses to those less than 50 years of age. A comparison of results by sex in the five exams of Generation 2 and in Generation 3 are shown in Figure 3 for the top associated LYPLAL1 SNP. The SNP by sex interaction for LYPLAL1 was significant in all Generation 2 exams, but not significant in Generation 3 subjects. However, when stratified by sex, the minor allele showed a consistent increase in BMI in men across generations (Figure 3). In contrast, in women the minor allele was associated with lower BMI in Generation 2 but not in Generation 3.
3.3. Association of LYPLAL1 SNPs with Obesity-Related Traits
To understand the relationship between LYPLAL1 SNPs and obesity in greater detail, we examined the top SNP from the present study (rs7552206) along with SNPs from the Lindgren et al. [12] and Heid et al. [8] studies for association with related phenotypes, including height, weight, WC, and WHR (Supplemental Table S4). The rs7552206 by sex interaction for BMI tracked with weight in all five exams, and with WC and HC in the two exams that had these data available. However, the waist and hip associations were completely or nearly completely attenuated when controlling for BMI. For rs2605100 (Lindgren et al. [12]), no compelling evidence of gene by sex interaction in central adiposity was found. Heid et al. [8] independently found a female-biased WHR association with LYPLAL1 (rs4846567), an SNP in moderate linkage disequilibrium with the Lindgren et al. SNP. We analyzed an available proxy for this SNP (rs2820446, Hap Map CEU ) and found a borderline significant gene-by-sex interaction with WHR (; Supplement S4).
3.4. Genome-Wide Association Analysis of Gene Main Effects for BMI
We also explored our cross-exam consensus approach for detecting significant main effects for BMI, using the same age-restricted datasets as the gene by sex interaction analyses. As with our gene by sex interaction analyses, the QQ plots show marked heterogeneity between exams (Figure 1) and modest inflation, which was not accounted for by population stratification. Only one SNP, located ~26 kb upstream of DUSP10 on chromosome 1, appeared among the top 1000 hits (Supplement S5) in all five exams of Generation 2 and was borderline significant in Generation 3 subjects (Figure 4). Interestingly, this locus is approximately 2.4 Mb away from the gene by sex interaction LYPLAL1 SNPs. No SNPs from prior genome-wide association studies of BMI showed up among our top 1000 consensus, including SNPs in the genes INSIG2, FTO [13, 25], and MC4R [26] (Figure 4). Surprisingly, the SNPs identified with the consensus approach yielded more significant values than other loci.
4. Discussion
We carried out a genome-wide assessment of gene by sex interaction for standard measures of obesity in men and women less than 50 years of age in the Framingham Heart Study. We took advantage of longitudinal data from multiple exams to identify loci showing consistent evidence of SNP by sex interaction across exams. Among the most prominent was a region ~100 kb downstream of LYPLAL1, encoding the lysophospholipase-like 1 protein. We found evidence across five exams, spanning a 20-year time frame, of opposite effects of genetic variants in this region on BMI in men and women. An attempt to replicate this finding in a later generation of Framingham Heart Study subjects found a consistent, significant association in men, but not in women, possibly indicating a male-specific association.
Ours is not the first study to link LYPLAL1 to obesity: two other genome-wide association meta-analyses identified this locus as having a sex-specific effect on WHR [8, 12]. While neither SNP is in linkage disequilibrium with the region identified in our study, the coincidental discovery of two distinct regions near the LYPLAL1 locus associated with obesity-related traits in a sex-specific fashion warrants further attention. Moreover, a prior linkage analysis of BMI in Generation 2 of the Framingham Heart Study identified a male-biased linkage for BMI in the vicinity of LYPLAL1 on chromosome 1q41 [11]. None of the other sex-specific obsesity loci from Heid et al. [8] were found in our study.
LYPLAL1 is a member of the lysophospholipase gene family (EC number 220.127.116.11). It was initially identified as a gene on chromosome 1 found incidentally during investigation of a familial chromosomal translocation [27]. It was named on the basis of ~30% predicted amino acid sequence homology with lysophospholipases I and II [28]. The sequence suggests an α/β hydrolase fold typically found in many lipases and esterases. LYPLAL1 was subsequently identified as one of 23 esterolytic/lipolytic proteins extracted from mouse adipose tissue. The presence of an active site serine was determined by activity tagging with a fluorescent probe of broad specificity, resembling a single-chain carboxylic acid ester. Similar probes modeling triglyceride and cholesteryl ester did not tag LYPLAL1 [29]. LYPLAL1 protein has not yet been isolated, however, and its substrate specificity is unknown. Along with the gene for adipocyte triglyceride lipase and several others related to lipolysis, LYPLAL1 mRNA was expressed more abundantly in abdominal subcutaneous adipose tissue from obese versus lean humans [30].
Given the minimal characterization of LYPLAL1, we can only speculate about its sex-specific role in adiposity. It might be involved in triglyceride synthesis or lipolysis, similar to some of the proteins with which it is coexpressed [31]. If indeed it is a lysophospholipase, it might play a role along with autotaxin, a secreted phospholipase D, in regulating extracellular levels of lysophosphatidic acid in adipose tissue. Via specific G protein-coupled receptors, lysophosphatidic acid has been shown to have varying effects on adipocyte differentiation and growth [32–34]. Another possibility relates to the endocannabinoid system, which has been a recent pharmacologic target for investigative obesity treatments. The monoglyceride, 2-arachidonoyl glycerol, as well as other esters or amides of long-chain polyunsaturated fatty acids belong to a family of compounds that are natural ligands for cannabinoid receptors. These endogenous signaling molecules affect physiologic and behavioral processes governing appetite and energy metabolism [31].
Interestingly lipolysis control has been shown to vary by sex in some studies [35] but not others [36]. The aforementioned study showing support for sex differences in lipolysis suggests that women show greater sensitivity to lipolysis in abdominal subcutaneous fat. The authors argue that the differences in lipolysis sensitivity are due to the presence of fewer inhibitory alpha-adrenergic receptors in the abdominal subcutaneous adipose tissue. This area of lipid metabolism is not well understood, but recent discoveries and conflicting opinions warrant further studies on LYPLAL1 and its potential roles and sex-specific effects in lipid metabolism and obesity.
Our analysis revealed marked heterogeneity of effects across different exams of the study, both in gene by sex interaction and main effect analyses, even among established loci from other genome-wide association studies of BMI. The consensus approach appears to be robust, identifying a locus with strong prior evidence of gene by sex interaction for obesity-related traits. Using this approach, we also identified a possible novel candidate locus for BMI, located ~26 kb upstream of DUSP10, encoding a dual specificity protein phosphatase. The DUSPs are a subclass of the protein tyrosine phosphatase gene superfamily that controls MAP kinase function [37].
Our study was carried out in the Framingham Heart Study Offspring cohort, a longitudinal, population-based study. Although no loci reached genome-wide significance in gene by sex interaction analyses, the longitudinal nature of the data allowed us to prioritize SNPs based on consistency of effect across exams. However, data on waist circumference were available only at two exams, limiting the effectiveness of our approach for these traits. Nonetheless, for BMI, this approach yielded a plausible candidate sex-specific locus and another sex-independent locus. Interestingly, in both of these cases, results from Generation 3 were not as significant as in Generation 2, possibly reflecting a cohort effect: Generation 2 subjects were enrolled nearly a decade or more prior to Generation 3 subjects. Generation 3 subjects were on average more overweight than Generation 2 subjects at comparable ages, consistent with temporal trends of increasing overweight/obesity observed in other population-based studies. These differences, driven in large part by changes in diet and physical activity over time, may impact the heritability over time and thus, the ability to detect genetic effects.
5. Conclusions
Few studies have systematically modeled gene by sex interaction for obesity-related traits on a genome-wide level. We confirm in our study that SNPs in the vicinity of LYPLAL1 may exhibit sex-specific effects on obesity-related traits. By utilizing a well-designed population-based study, and taking advantage of longitudinal data, we were able to demonstrate this effect using a much smaller sample size than the original meta-analysis that identified this locus. This has implications for the design of GWAS, where large samples sizes are often sought sometimes at the expense of population homogeneity. We suggest that smaller epidemiologically sound population-based studies may be more powerful than larger heterogeneous metacohorts. We also highlight the importance of considering longitudinal robustness of association within a cohort as another means of prioritizing loci and reducing false positive associations. Future studies of LYPLAL1 are needed to determine the basis of the apparent sex-specific effect on obesity.
The authors would like to thank the National Heart, Lung and Blood Institute (NHLBI) for creating the open-access Framingham SHARe resource, and all of the study participants and Framingham Heart Study investigators who helped to create this tremendously valuable resource. The Framingham Heart Study is conducted and supported by the NHLBI in collaboration with Boston University. This manuscript was not prepared in collaboration with investigators of the Framingham Heart Study and does not necessarily reflect the opinions or views of the Framingham Heart Study, Boston University, or the NHLBI. This work was supported in part by National Institutes of Health Grants: RO1 HL085191 to J. McCarthy, PI. Jennifer Rowell was supported by NIH training Grant T32-DK007012-31 (Feinglos, PI), and Ashlee Benjamin by training Grant T32 GM071340 (Harer, PI).
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1.1 Project Description:
1.2 Problems and Issues:
I am trying to implement skins (client-side) in-game. A skin is basically a picture or a image (.png format). When a player selects a skin, the image gets drawed on his cell.
Here is the issue: I can get it to apply the image, but it does that for every cell in-game, including other players. It's only supposed to apply the image for your own cell.
1.3 Pictures
Here is a picture of a cell without skin: [url removed, login to view]
Here is a picture of a cell with a skin: [url removed, login to view]
9 freelanceria on tarjonnut keskimäärin 26 £ tähän työhön
Hello ! thank you for your post. I have read the your description carefully. I have the sufficient experience in developing of web app(animation, game, drag/drop, editing/processing image. drawing diagram, html5 fl Lisää

subset: commoncrawl


text:
|Lawless Spanish
Free Spanish Lessons
Online language learning with Laura K. Lawless
|Lawless Spanish > Spanish Lessons > Vocabulary > Numbers > Ordinal Numbers and Fractions
|Números ordinales y fracciones
- Spanish Ordinal Numbers and Fractions
Ordinal numbers are used to express rank or position, while fractions express a portion or part of a whole.
All ordinal numbers have feminine forms - just change the o to a: la segunda (2ª), la séptima (7ª)
Fractions may also be used with parte:
When primero and tercero precede a masculine noun, they change to the short adjectives primer and tercer
Beginning with fifth, Spanish ordinal numbers and fractions are the same word; only the article distinguishes them: the fifth = el quinto, a fifth = un quinto
The ordinal numbers up to tenth usually precede the noun. After tenth, however, ordinal numbers are commonly expressed with just the cardinal number after the noun:
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text:
VATICAN CITY, NOV. 21, 2006 (Zenit.org).- At the request of Benedict XVI, a dossier on the question of condoms was submitted by Cardinal Javier Lozano Barragán to the Congregation for the Doctrine of the Faith.
The cardinal, who is president of the Pontifical Council for Health Care Ministry, revealed this today during a press conference to present the council's upcoming conference on "Pastoral Aspects of the Treatment of Infectious Diseases."
The question is now in the hands of the doctrinal congregation, Cardinal Lozano explained, "because our pontifical council does not have doctrinal but pastoral tasks."
"Thus, in keeping with the Holy Father's wish, we have carried out a careful study on the use of condoms, both from the scientific as well as the moral point of view, and we have submitted it to the Congregation for the Doctrine of the Faith," the cardinal said.
Mentioning Pope John Paul II's postsynodal apostolic exhortation "Familiaris Consortio," Cardinal Lozano clarified that no position of the Church on the matter should lead to thinking that it can encourage frivolous conduct in the matter of sexual morality.
The cardinal revealed that the dossier gives objective data on the use of condoms, as well as a range of pastoral positions adopted in the world.
He noted that it is not up to the Council for Health Care Ministry to decide whether it is necessary to make a pronouncement or to respond to this question.
The prelate added that the matter remains in the hands of the "special wisdom" of Benedict XVI and his charism as Successor of Peter, assisted by the Holy Spirit.


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Saturday football action - LIVE updates
Keep up with the build-up, team selections and live match updates as Wolves, West Brom, Aston Villa, Walsall and Birmingham City are all in action.
There are no fewer than three Midlands derbies this afternoon, with Wolves hosting Birmingham, Aston Villa taking on Stoke and Walsall travelling to Coventry.
Meanwhile, West Brom welcome Arsenal to The Hawthorns.
Sorry, we are not accepting comments on this article.


text:
Home > Patient's Guide > Glossary of Terms> Permanent Cardiac Pacemaker
Glossary of Terms
Permanent Cardiac Pacemaker
A pacemaker is used to treat very slow heart rhythms. A pulse generator is implanted beneath the skin below the collarbone; a pacing wire connects the pulse generator to the heart and carries electrical impulses. The rate of impulse formation controls the heart rate and does not allow the heart to slow below a certain rate.
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text:
Girls Soccer
The Magic lost 1-0 to Rogers last Thursday, before falling 3-0 at STMA on Tuesday night.
Monticello lost a close dual meet to Buffalo last Thursday, but bounced right back on Saturday to take second at the Spring Lake Park Invite, including finishing ahead of Buffalo.
Monticello reeled off five straight wins last week, bookending a tournament win at Hutchinson with big wins over conference leading STMA, and against Buffalo, who defeated the Magic the first time through the schedule.
Boys CC
Led by Colin Lyndorff's 18th place finish, the Magic took seventh at the Lucky Lindy Invite on Saturday.
The Magic fell to Buffalo in three sets Tuesday night.


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Community Forums › Forums › Design Tips and Tricks › How do i change Featured Page widget html output for a specific hover effect?
Tagged: featured page, widget
This topic contains 3 replies, has 2 voices, and was last updated by Seb 3 years, 4 months ago.
May 13, 2014 at 9:54 am #104920
I had a post before: http://www.studiopress.com/forums/topic/change-featured-page-widget-on-enterprise-pro-homepage-to-a-hover-effect/
This is perfectly possible, but i want to create something more responsive specific with only html5 and css:
As you can see, all the content in this example is wrapped inside the image link:
The reason for this is that the absolute layered divs (the content):
div.hovertitle' and 'div.hovercontentneed to be clickable. If you take these 2 divs out of the link, they block the 'function of the link' when you hover over the image-block.
Now the standard featured page output is:

I would like to put the

 inside the
after the
like this:

Now i took a look at the genesis-featured-page.php file and i understand a little, but far from adjusting it create this output :S.
How do i change this? Is there an easy way? Do i need to copy and paste some rules inside the genesis-featured-page.php file?
Thanks for reading my post,
GreetzMay 13, 2014 at 9:09 pm #105038
I'm not sure I understand what you're hoping to do vs. what is already happening, but you should never, ever edit the Genesis framework files. You could create a file with the same name in your child theme's folder to house changes, but nothing in the /genesis/ folder should be touched.
It may be worth your time to consult with a developer on this one - there are a number of devs that are recommended by StudioPress listed here: http://www.studiopress.com/genesis-developers
Andrea Whitmer, Owner/Developer, Nuts and Bolts Media
I provide development and training services for designers • Find me on Twitter and Google+May 14, 2014 at 1:29 am #105050
Thanks for the info Andrea, i always keep a copy if i change something, but there is a better place for that, you make me see ;).
I want to make the custom content, i layer upon the image, clickable as a link. As 1 block. To behave as 1 link. I think the only way to accomplish that with HTML5 and CSS3 is to move the div-p-a output inside the link.May 14, 2014 at 3:08 am #105056
I found a solution for this, it was obvious in my example code already: pointer-events:none; for the absolute positioned elements that you want the pointer functionality to shine through.
The only problem is: it's not that browser version friendly: http://caniuse.com/pointer-events
So i'm still looking for the right way to adjust the featured-page-widget.php file inside the child theme :S.
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In the wake of the announcement of her marriage to Egyptian megastar Tamer Hosny, Moroccan ex-Star Academy contestant Basma Boussil [2]has - in a dramatic move - as sudden as maiden became madam - permanently quit her singing career. The starlet had only just broken into this doomed career.
Tamer, turning out to be quite the demanding groom, had insisted that Basma abandon her dream and dedicate herself completely to him and her new family. Prior to this whirlwind matrimony, Basma was on the cusp of signing a new album. Tamer scuppered her plans, nipping her musical career in the opening credits.
The news of the marriage [3] had earlier stunned fans who were left divided into camps for and against the union.
But this hasn't stopped the newly wed love-birds who are in fully-fledged honey-moon mode, preparing for their first married jaunt - a joint religious pilgrimage Hajj. [4] Tamer said that he wants his marriage to start off as he prays for it to go on - blessed by God.
Share your opinions: What do you think of Hosny's marriage and early wedded moves? Do you think the public should leave out their scathing judgement and just wish the man well in his married life?
[1] http://www.syndigate.info
[2] http://www.albawaba.com/entertainment/tamer-hosny-wedding-440511
[3] http://www.albawaba.com/entertainment/tamer-hosny-married-441012
[4] http://www.albawaba.com/editorchoice/why-saudi-men-prefer-perform-hajj-alone-399390
[5] http://www.albawaba.com


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Seal Removal Tool, LH And LU
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Zoro #: G2409127Mfr. Part #: 54677-0000
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Technical Specifications
|Zoro #: G2409127 Mfr #: 54677-0000
|Item: Seal Seat Removal Tool
|Includes: 1 Tool
|Country of Origin (subject to change): United Kingdom
Product Description
Seal Seat Removal Tool , For Use With 6UTP3 To LH640-1890, Includes 1 Tool
Restrictions and Compliance
- This product is not intended for potable water applications (human consumption – drinking and cooking) and has not been designed to be compliant with the "Safe Drinking Water Act" requirements for low lead in potable water applications. This item is for use, only, in non-potable (non-human consumption) water applications.
- ***
- This is a restricted item. It cannot be used in the USA for potable water applications.


text: Icon's satisfying a lot of rider's wishes by creating the Icon Variant, a helmet that combines off-road looks, ventilation and peripheral vision with street refinement. We've been impressed with the progress Icon has shown in quality; this helmet moves them one step closer to competing with established helmet makers with the use of a carbon/dynema/fiberglass composite shell and a moisture wicking liner. Full details covered in the video below. And don't worry, it comes in classy plain colors in addition to the godawful skulls and other macho ephemera. >


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> I'm looking at the possibility of implementing a photo gallery for my > web site with a tree structure, something like: You don't really want a tree structure, because one day you'll want to put the same photo in two galleries. Suppose you take a very interesting photo of celery during your trip to china, you might want to create a 'Trip to China' folder, and also a 'Celery' folder for your other celery photos... well, if you don't like vegetables, it also works with people, moods, geographic regions, themes, etc. You could define this structure : You could then define tables describing themes, and/or keywords, link photos with these themes and keywords, and define a folder as either being a specific collection of photos, or as a collection of one or several themes. From a tree, it becomes a bit more like a graph. Themes can also be organized and relationed together. This opens the path to easy searching and cataloguing ; is not that much more difficult to do, and in the end you'll have a much better system. > How would I go about creating a view to show a) the number of photos in > a gallery and b) the timestamp of the most recent addition for a > gallery, so that it interrogates all sub-galleries? If you're concerned about performance, you should do this in a materialized view updated with triggers. If you can afford a seq scan on every time, a few stored procs should do the trick.
Next: From: Thomas F.O'Connell Date: 2004-11-16 19:45:45 Subject: Counting Distinct Records Previous: From: Bruno Prévost Date: 2004-11-16 16:49:11 Subject: Re: Table definition


text:
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McGard Lug Nut 7/16 X-Long Shank Race 63001 Shank w/ Washer Lug Nuts
7/16" x 20 RH Open End Chrome Plated Steel (Set of 4)Pit Stop USA offers McGard Lug Nut 7/16 X-Long Shank Race 63001 at low everyday prices. Be sure to check out all of our products from McGard including McGard Lug Nuts.Product Description: Lugnut, Premium, 7/16-20 in Thread, 13/16 in Hex Head, 1.365 in Shank, Open End, Washers Included, Steel, Chrome, Set of 4
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text:
Senators Martins and Skelos Talk Job Creation and Economic Development with President Obama's Economic Advisor
State Senator Jack Martins and State Senate Majority Leader Dean Skelos recently met with Citigroup Chairman and former AOL Time Warner Chair Dick Parsons to talk job creation and economic development. The luncheon took the form of a question and answer forum that discussed a wide range of economic issues that impact small business, downtowns and emerging local markets for communities throughout New York State and Long Island. Senator Martins also took the opportunity to bring three Elmont youth leaders to the luncheon gathering. Local residents Marvin Lee, Franklin Thomas and Tyrone St. Louis attended the luncheon where a question and answer period took place centering on the economy, job creation and emerging markets for New York and Long Island.
Mr. Parsons currently serves on President Obama's Economic Advisory Board. He also served on former President Bush's Social Security Advisory Board and serves as Chairman of the New York City Partnership. Parsons began his career working with Governor Nelson Rockefeller and was part of Mayor Mike Bloomberg's transition team. Outside of his work with economic and job creation affairs, Parsons serves on World Trade Center Memorial Foundation.
"The discussion about creating jobs and promoting economic development was lively and very insightful," said Senator Martins adding, "Dick Parsons is an incredibly talented individual who has made important and lasting contributions to our State and Country. I'm glad to have had the opportunity to meet with him and bring our next generation of leaders to the forum luncheon. It's my hope that we can continue to bring the 'can-do' attitude Dick Parsons brings to economic development to all our communities."


text:
Shane Byrne holds off the advances of Tommy Hill to score his fourth British Superbike Championship win of the season at Brands Hatch.
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Shane Byrne has won his fourth race of the 2011 MCE British Superbike Championship season after prevailing in an absorbing battle with key title rival Tommy Hill.
Both Byrne and Hill came into the second race of the weekend determined to make up for failing to score in the opening encounter, both riders having been caught out by an ill-advised tyre choice in tricky conditions.
Nonetheless, having taken advantage of a grid determined by fastest laps from race one - with those who pitted for slick tyres benefitting over those that stayed on intermediates -, Hill got away well from pole position to lead into the opening bends.
Joan Lascorz and Michael Rutter gave chase, the latter edging ahead of the factory Kawasaki rider by the end of the lap, though both would soon find themselves behind Byrne as he carefully worked his way into contention.
On the tail of Hill's Swan Yamaha by lap four, Byrne pushed ahead into the lead on lap six and set about trying to pull away from his rival.
As it happens, Hill stayed close to Byrne, but his efforts to wrest the lead off the HM Plant Honda rider were restricted to a failed overtake at Paddock Hill Bend on lap 13, Hill going through but running wide and allowing Byrne back ahead.
Indeed, though Hill stayed close to the chequered flag, Byrne rebuffed his every effort, enabling him to come home a winner for the first time since Thruxton.
Behind Hill, John Hopkins made good progress from 12th on the grid to come home in third place, the American unable to do much about the leaders once he had dispatched of Rutter.
Another bold ride from Rutter was rewarded with fifth place, just behind Michael Laverty, while race one winner Josh Brookes was a solid sixth after being forced to work his way up the order again from 13th on the grid.
The fight for seventh went down to the wire, with four riders covered by less than four tenths of a second. In the end, Lascorz secured the spot, just ahead of Jon Kirkham and Martin Jessopp, the latter making up good ground in the closing stages, while Peter Hickman rounded out the top ten.
Graeme Gowland took EVO honours once again with a fine ride to 11th, ahead of reigning champion Ryuichi Kiyonari, whose poor start from the front row saw him languishing at the bottom end of the top fifteen throughout the race.
Broc Parkes, Glen Richards and Chris Walker completed the points, while there was disappointment for race one podium winner Gary Mason after he crashed out of a top ten finish.
The grid for race three, meanwhile, will see Hill on pole for a third time, ahead of Byrne, Hopkins and Laverty.


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SOUTH Tyneside now has just three core day centres – the Father James Walsh Centre in Hebburn, and Perth Green Community Centre and the Phab Club, both in Jarrow.
As a result of the review, the day centre at Gainsborough Avenue, South Shields, is to be re-located – to an as-yet unknown location.
Centres at Wilfred Street, Boldon Colliery, and Hampden Street, South Shields, are to close – with services moving to the Father James Walsh Centre.
Services in Ocean Road Community Centre and the Cleadon Park health centre, both South Shields, are also to move and will form part of the council's new model.
That will result in service users being directed by staff at a new community hub – eventually to be established on the site of the former Wouldhave House building at South Shields' Market Place – to alternative services across the borough that meet their individual needs.
The council has pledged it will provide transport "where needed" for service users to reach alternative venues.
The council says the new 'flexible approach' to day services is a way to safeguard and improve services to ensure they are "sustainable in a difficult financial climate".
A spokesman said: "It's about safeguarding services rather than focusing on the buildings where they have taken place in the past.
"By using a smaller number of bases, we will spend less on maintaining expensive and inefficient buildings, and more on the activities and support that many people have told me they value so much.
"Almost nine out of 10 people in consultations supported the idea of a new central hub for day services.
"Rather than being attached to a particular base and either taking part in activities there or travelling from there to activities, service users will access activities through a central hub which provides advice, information and signposting rather than activities themselves.
"This approach means service users and their families can have more choice and a wider range of activities, as well as in some cases having the option to travel directly to their activity rather than going to a centre first and travelling on from there.
"The central hub will be based in the new 'community hub' building on the Wouldhave House site – in the meantime we are looking at a number of options for a temporary base."
The future of the units axed is yet to be decided.


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House Hearings Didn't Move Voter Opinion on Benghazi (Because the Media Haven't Really Covered the Story)
Rasmussen finds that the average American remains more interested in irrelevant trials and the latest controversial "teen mom," then the cover-up in Benghazi.
A new Rasmussen Reports national telephone survey finds that 31% of Likely U.S. Voters rate the administration's explanation of the events surrounding the murder of Ambassador Christopher Stevens as good or excellent. Forty-one percent (41%) think the administration has done a poor job explaining things. (To see survey question wording, click here.)
It's difficult for the hearings to make much impact when they took place on a single day rather than shorter hearings across a week, and when the networks bail out of covering them to put the Jodi Arias verdict on the air. As I wrote toward the end of the day-long hearings last week:
Juxtaposition on my screens in my blogging lair: Streaming video from the Benghazi hearing, which is an investigation into what may be a massive cover-up at the highest levels of our government, and the verdict from the Jodi Arias trial on the cable nets. Thousands are waiting outside the courtroom for the verdict to be read, just standing around, even though the verdict tells us nothing about the credibility of our government or its ability to defend US interests around the world. The networks aren't even carrying the Benghazi hearing at this point, despite the fact that the allegations aired in it are so disturbing. This is the power of the media and what it chooses to emphasize and downplay, on full display.
Those thousands were there because the media had hyped that trial and made the reading of its verdict a Moment. Many of those thousands, along with millions more Americans, might care more about Benghazi if the alleged news media gave the story proper attention and treatment. Eight months in, they're finally starting to. Progress, I guess.


text:
This thread is for those who are first and foremost about obtaining substantial amounts of glimmer. Also feel free to post stories/images/videos/music about making/spending money/glimmer.
I did things I was not proud of to obtain my beta glimmer. Dirty, filthy things, performed in the dark corners of the cosmodom. My shame will forever haunt me. Say no to glimmer, just say no!
There was a cap on obtaining glimmer in the Beta of 25,000. Anyone know if that remains in the full game?


text:
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5 thoughts on "Houston"
It's quite difficult for me to understand the reason for this post on a Christian blog of this caliber. Are we to understand that Ms. Houston is being portrayed here as a Christian lady worthy of emulation? Evidently her lifestyle was hardly one of a Christian role model, and her death has been attributed to the effects of drugs and alcohol. Please help me comprehend this addition to your otherwise worthy ministry on this blog.
Dear Ray,
Thank you for posting this song. It caught my attention that you did not post any personal comments. I gathered quickly that you were letting the "words" of the song speak for themselves. Beautiful…
I was not a Whitney Houston fan, but was home recovering from an illness and watched nearly all of her home going service. It was exciting to hear the Gospel of Jesus being preached and even some rocks crying out. The two words that came to mind when I heard the news of her death-totured soul. Did she live the kind of life that I would want my teens to emulate? Of course not. But what an opportunity to dialogue with them about the human condition-we're all in desperate need of Jesus!
Praying that Anne Rice does not read Richard's comment.
Grace and Peace to you!
Thanks, Dr. Ortlund. Watching celebrities spin out of control over the years, I've decided that fame must be a heavy burden. Yes, they sought it and worked hard for it, but when they reached their zenith they apparently realized it simply wasn't enough. It was easy to be lured into drugs and alcohol. They were filled with an emptiness that money & fame can't overcome. I believe Ms. Houston knew the truth, though. Her parents raised her in the church and no doubt her mother was heartbroken by her daughter's sad decline. It's interesting to note that apparently most of Whitney's closest friends are solid Christians who tried to help her. Sad end for a truly talented woman.
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Ray Ortlund
Ray Ortlund is senior pastor of Immanuel Church in Nashville, Tennessee, and serves as a Council member with The Gospel Coalition. You can follow him on Twitter.


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Many of us have been trying to figure out how seriously to take the NFL's three-day negotiating window prior to Tuesday's official start to free agency, which opens in a little more than an hour. Would major agreements soon be apparent, even if they weren't confirmed by the primary participants?
Would we at least get a clear idea of the primary suitors for key free agents?
Or would it just be a whole lot (more) of talk?
Based on an NFL memo sent Friday, and reported on by ESPN's Adam Schefter, it sounds as if the league wants nothing more than the final option to take place this weekend. This is our first go-around with the three-day window, but from the sounds of it, we might not get much in the way of hard news over the next few hours and perhaps days.
The memo made clear the league won't allow a team to enter "into an agreement of any kind, express or implied, oral or written, or promises, undertakings, representations, commitments, inducements, assurances of intent or understandings of any kind concerning the terms or conditions of employment offered to, or to be offered to, any prospective Unrestricted Free Agent for inclusion in a Player Contract after the start of the new League Year."
The league also threatened a tampering investigation if an agreement is so much as reported on by a media organization. The early guess is that the memo will cause teams to pull way back on any aggressive plans, at least anything that could be rooted out by reporters, over the next few days. We'll see if that is in fact the way it works out. I'll stay up as long as I can this evening, and then circle back with you in the morning.
Note: The one bit of news we do have in the NFC North is that Bears defensive tackle Henry Melton announced his intention to sign his $8.45 million franchise tag. The biggest implication of that action: The Bears can no longer rescind the tag if they change their minds or sign/draft a replacement for him.


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One strange vagary of Netflix on the PlayStation 3 is that it has multiple interfaces… with different levels of access to Netflix features.
What could explain such a strange occurrence? According to Netflix's Chief Product Officer Neil Hunt, it's simple: it's all about gathering data on the optimal interface through testing.
Hunt explains:
The most visible test at present is between three quite different user-interfaces on the PS3 streaming application…
We test a lot of algorithmic and data-level variations in movie discovery. We explore large and small variations on the recommendations system, including positioning and tools for input of taste preferences, ways to present recommendations, whether or not explaining recommendations drives credibility, etc.
We explore such basics as play and add-to-queue button placement, size, and functionality. We tested the switch last year of whether the home page should be DVD or streaming focused.
We even test things like page load time, and streaming encoding quality, and streaming startup time, to know which of those kinds of optimizations should get the most of available engineering attention.
If I had to summarize our learnings in three words: "simple trumps complete."
Bad news? For power users, yeah. But for the 99% of Netflix users that just want to stream already, this is a manifesto towards excellence.
Read more at Quora [via Netflix]


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gymnospermy is a valid word in this word list. For a definition, see the external dictionary links below.
The word "gymnospermy" uses 11 letters: E G M M N O P R S Y Y.
No direct anagrams for gymnospermy found in this word list.
Adding one letter to gymnospermy does not form any other word in this word list.Words within gymnospermy not shown as it has more than seven letters.
Try a search for gymnospermy in these online resources (some words may not be found):
Wiktionary - OneLook Dictionaries - Merriam-Webster - Google Search
Each search will normally open in a new window.
List all words starting with gymnospermy, words containing gymnospermy or words ending with gymnospermy
All words formed from gymnospermy by changing one letter
Other words with the same letter pairs: gy ym mn no os sp pe er rm my
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Previous word in list: gymnosperms
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Some random words: luau pfennig other raff praam gip cebid
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It only takes a minute to get started. Fill out our uncomplicated sign up form and login to the site.
This step is noncompulsory but will greatly increase your chances of getting noticed by other people on the website. Tell people about yourself, your pasttimes and upload a nice photo of yourself.
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And start dating


text:
The AARP today announced their support for the Senate's health insurance reform package, lending important momentum to the debate. In his letter to Senate Majority Leader Harry Reid, AARP CEO Addison Barry Rand said:
We appreciate your leadership in developing and advancing the Patient Protection and Affordable Care Act in the Senate. This bill will strengthen Medicare by eliminating cost barriers to preventive care, reform Medicare's payment and delivery system to promote care coordination, and reduce hospital infections and preventable readmissions…With your commitment to closing the doughnut hole in conference, consistent with the President's pledge, and the many positive features referenced above, AARP is pleased to support your efforts to obtain cloture, and urges timely passage of this legislation by the Senate.
Reid released the following statement this afternoon in reaction to their support:
"I appreciate AARP's support for our historic health reform bill. As an important voice for millions of American seniors, they know better than anyone how seniors are being overwhelmed by skyrocketing health care costs. Their decision to stand with us to ensure quality, affordable health care for America's seniors continues the strong momentum that is building behind health reform.
"In addition, I reiterate the commitment that I made along with Chairmen Baucus and Dodd on the Senate floor last night to close the coverage gap in Medicare Part D. Closing this gap, known as the 'doughnut hole,' would help over 58,000 Nevada seniors. AARP believes that this action is an essential part of reform that will help control costs. Our seniors, in Nevada and around the country, should be able to make critical medical decisions based on the care that they need, not what they can afford.
"Our bill saves money, saves lives and saves Medicare. Meaningful health reform is in sight, and Senate Democrats are committed to reaching the finish line."


text:
CHP investigators believe alcohol was a factor in a fatal traffic accident southeast of Lompoc, which took the life of a young woman.
A vehicle was found overturned off of Highway One, on Santa Rosa Road early this morning.
Investigators think the female driver lost control of the VW bug, and drifted onto the right shoulder.
They believe she then over-corrected across the road, hitting an embankment, and flipping the vehicle.
The 24 year old Lompoc woman wasn't wearing a seat belt, and died at the scene. Her name hasn't been released yet.
It's unclear as to when the accident happened, with officers saying it was sometime between 11 p.m. Wednesday, and six this morning on the lightly travelled road.


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Jack Dragna
Apr. 18, 1891
Cittŕ Metropolitana di Palermo
Sicilia, Italy
Feb. 23, 1956
Los Angeles
Los Angeles County
California, USA
Organized Crime Figure. Made member of the Chicago Cosa Nostra. The most successful, but least known of any Los Angeles crime boss. He was not a publicity seeker like Bugsy Siegel and Mickey Cohen, which allowed him to die of natural causes and not to pass away in jail. He lived in Los Angeles most of his career, and made his living off of gambling and prostitution. He, along with mobser Johnny Roselli ran a telgraph system called the "Race Wire". It allowed bookie joints to get fast racing information. Later, the New York Mob sent Bugsy Siegel out to get a piece of the action. When Siegel was murdered, Dragna attempted to take over his rackets. This put Jack Dragna into a long feud with Mickey Cohen. Many attempts were made on Cohen's life, but they were never successful. When he died, the L.A. mob was taken over by Frank DeSimone. Dragna was the only L.A. crime boss to ever hold a seat on the national Cosa Nostra Commission.
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Joe Walker)
Calvary Cemetery
Los Angeles
Los Angeles County
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New Delhi: An auction for radio spectrum on the 800MHz wave length fetched the government some Rs.3,500 crore after three rounds of bidding, but was barely a tenth of what it had hoped to raise.
Sistema Shyam Teleservices Ltd was the only bidder and won the frequencies in eight telecom service areas, according to two officials of the department of telecommunications (DoT), who spoke on condition of anonymity.
"The process had to be followed" even if there was just one bidder, one of the officials said. Sistema Shyam won permits to use the spectrum at the minimum price because there was no competition.
The total value of the air waves it won is Rs.3,639 crore. The eight circles include Delhi, Kolkata, Gujarat, Karnataka, Tamil Nadu, Kerala, western Uttar Pradesh and West Bengal. The company already has operations in Rajasthan.
Radio spectrum on 800MHz is used in India by telecom operators to offer voice and data services through the code division multiple access, or CDMA technology platform.
The government, however, is unlikely to see any of the money coming in till 2016, as the operator will be allowed to offset its dues against the money paid in January 2008. Of the Rs.3,639 crore to be paid, Sistema Shyam has earlier paid Rs.1,626 crore. It therefore owes the remaining Rs.2,013 crore to the government, which will only be due from March 2016 as the government has provided telecom operators a moratorium period of three years. After March 2016, Sistema Shyam will be allowed to pay in 10 equated yearly instalments of around Rs.200 crore.
The lower-than-expected revenue will further put pressure on the fiscal position of the government, which has set a target of containing the fiscal gap to 4.8% of gross domestic product in the year to March 2014. To meet this target, it expects Rs.40,000 crore from the telecom sector, of which half is expected from the auction of radio spectrum in 2013-14.
There would be more auctions in the next 12 months, according to DoT secretary R. Chandrashekhar.
The government had set a minimum price of Rs.9,100 crore for the auction of 5MHz of CDMA spectrum across the country, half that of the bench price set before an auction in November.
The reserve price for spectrum on the 900MHz wave length was Rs.23,752 crore and Rs.11,876 crore for 1800MHz, for 5MHz pan-India. There were no bidders for these frequencies that offer wireless services on the global system for mobile communications, or GSM platform.
Sistema Shyam had applied for spectrum in 11 circles but bid for eight, which means the company will shut operations in Mumbai, Maharashtra and eastern Uttar Pradesh, the DoT officials cited earlier said.
In a statement, the telecom operator said it will focus on a data-centric, voice-enabled strategy and its auction strategy was based on a number of factors including pricing, number of slots available, competition, and data potential in the areas.
Sistema Shyam has won three slots of 1.25 MHz of CDMA spectrum—3.75MHz in total—in each circle, and expects its operations in nine circles to cover 40% of India's population, 60% of data potential and safeguard 75% of its current revenue, according to the company.
It was one of nine companies affected by the 2 February, 2012, Supreme Court judgment that cancelled 122 telecom permits and spectrum allocated in January 2008.
The company has started procedures to stop operations in Mumbai, Maharashtra and eastern Uttar Pradesh, where it did not bid. This will impact another 1.5 million subscribers and some 15%, or 400, of its employees.
"Full efforts are being made to absorb maximum number of employees in other circles," the firm said in a statement. "In addition, care is being taken to place some of the employees in other companies."
Earlier this week, Sistema Shyam had announced that it was closing operations in 10 circles, affecting around 2.2 million of its 12 million subscribers. The government has also allowed operators to pay 25% of the winning bid amount upfront and the remaining after a two-year moratorium in equated yearly instalments. This means the government is unlikely to get any money from the auction for the next few years.
Sistema Shyam is a joint venture between Shyam Group that holds around 26% equity, with the rest held by Russian conglomerate Sistema JSFC and the Russian government. The company, which runs the MTS brand of mobile telephony services, has so far invested over $3.2 billion in the India telecom sector, the company said.


text:
NewswireToday - /newswire/ -
Omaha, NE, United States, 2010/02/23 - Net-tech Distributing, Inc. wins more Middle Eastern Sales for the Condux International Tools and Equipment lines.
Net-tech Distributing, Inc. as the leading Condux Distributor of aerial and underground cable installation, cable pulling equipment and cable installation equipment, consider Net-tech Distributing, Inc. as your premier Condux distributor for all your Cable Puller, Ball Bearing Swivel, Duct Rodder and other aerial and underground cable installation equipment and tool needs.
Condux International has been manufacturing cable installation tools and equipment for over 30 years. Working directly with Net-tech Distributing, Inc. to serve the electrical utility, telecom and CATV industries, Condux offers the highest quality tools, engineered to reduce installation time and increase safety. Throughout its history, Condux has been committed to innovation. This commitment is illustrated through the continual research and development of new tools for aerial and underground cable installation. To learn more about this news release please contact Net-tech Distributing, Inc. 800-290-7752 Toll Free or 402-896-6093 for International calls.
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text:
It's time once again for those of us looking into the past to look into our
future. So here are my genealogy goals and my plans on how to achieve
1.Work more on my maternal lines
Plan: Try to get into Boston and find the divorce record for my Mom's parents,
Send away for my McFarland grreat grandparents death certificates and any
other documents which might definitely establish their place of birth
2.Continue researching my paternal lines
Plan: I'm hoping to have the Ellingwood collateral lines done by midyear and
continue working on the others. The more recent Barker, Dunham and Coburn
lines in particular. As in last year, I need to get out more to the NEHGS and the
local Family History Center. And I still haven't made it into the Mass State Archives!
The trips to the local cemeteries have turned up family connections so I'll be
continuing those. I also hope to attend the Ellingwood Reunion again this year.
3. Break down that John Cutter West brick wall!
Plan: Same as last year: "A series of visits to the town halls and historical societies
of towns here in Plymouth County seems to be the only approach possible to
this mystery. The cemetery visits might also prove useful in this."
4. Join a local genealogy or historical society.
Plan: I'm ashamed to say I still haven't done this. I hope to change that soon. Work
schedule is no longer an obstacle.
5. Continue with Find A Grave activities
Plan: Get back to visiting the local cemeteries, taking pictures and posting them to
Find A Grave. This is a bit hindered right now by my lack of transportation but I
hope to have that taken care of by the end of this month.
6. Trim My Tree
Plan: I am paying the price of heedless gedcom downloads from PAF from when
I was a clueless newbie ten years ago, Multiple entries for one person and more
remote ancestors of dubious connections need to be removed. I made a start of this
in 2011 and must continue do so. The flip side of this is to be more vigilant in
adding new names and remember to cite sources.
7. Write more.
Plan: Continue blogging and try to equal if not surpass my output of 2011. I had
248 posts on West in New England, and 42 on The Old Colony Graveyard Rabbit.
I enjoy sharing the stories that I've discovered in my research.
8. Organize, Organize, ORGANIZE!!
Plan: Same as last year: JUST DO IT!
9. Scan, scan, SCAN!
Plan: See #8
Last year I said that a lot of what I would accomplish would depend on my health.
This year I'm happy to say I don't see my health as an obstacle. Transportation has
been a problem for the past few months but I'm hoping to have Ping the Wonder
Car back on the road soon.
But as it has been in previous years, my biggest goal in my genealogy research is
to keep having fun with it!
A blog about genealogy and thoughts about the various roots and branches of my family tree as well as the times in which my ancestors lived.Included are the West, White,and McFarland families.WARNING:DO NOT TAKE ALL OF MY FAMILY RECORDS AS GOSPEL. ALWAYS CONFIRM YOUR OWN RESEARCH!
Sunday, January 01, 2012
2 comments:
- Marian Pierre-Louis said...
I'm with you on so much of this, Bill! Especially number 6, that's why I'm starting over. I look forward to reading your posts. We can commiserate as we make progress. Happy New Year!
- Cheryl Cayemberg said...
Oh, Bill, I so understand #6! I'm trimming my tree too!
Subscribe to: Post Comments (Atom)


text:
KARACHI, Sept 22: A former minority member of the Sindh Assembly, Malik Ata Mohammad, was gunned down outside his under-construction home in Mehmoodabad on Saturday, police said.
They, however, ruled out any political or religious motive for the killing, citing that the victim was targeted for personal reasons and the attackers had already been identified.
"The 63-year-old victim was sitting on a charpoy outside his home when three men riding a motorbike entered the street in Punjabi Gali, Mahmoodbad No 3," said Baloch Colony SHO Inspector Murtaza Majeed. "They stopped and one of them fired multiple shots at Mr Malik before speeding away with his accomplices. He sustained five gunshot wounds and died on the spot."
The body was later moved to the Jinnah Postgraduate Medical Centre for medico-legal formalities, the SHO said, adding that the victim had a dispute with a group over a piece of land and some other real estate properties.
"Even the family recognised the fact and believed that the same group was involved in the killing of the victim who was an Ahmedi. The family is aggrieved and busy in funeral arrangements. But they have shared their concerns with investigators and three suspects would be nominated in the FIR," added the officer.
Mr Malik was elected a Sindh Assembly member in 1997 as an independent candidate on a minority seat and joined the then ruling party Pakistan Muslim League (Nawaz). However, his political loyalty shifted to the PML-Q after the 1999 coup staged by General Pervez Musharraf and gradually left active politics.
Clash leaves one dead
In Malir, an elderly passer-by was killed and another sustained a gunshot wound in an armed clash between two 'criminal gangs', police said.
The officials added that the two groups said to be involved in drug peddling and running gambling dens in the area exchanged gunfire in the Gharibabad area of Khokhrapar.
The clash left 55-year-old Munawwar Ali dead and 35-year-old Mohammad Akbar wounded.
"There is an old dispute between the two groups that turned ugly today," said an official at the Malir City police station.
"Raids are being conducted for the culprits' arrest. The police have detained some suspects and they are being interrogated," he added.


text:
4 Freebies!
4 Freebies: By Laura Harris
No need to wait for Santa and his reindeer to drop off your gifts!{} Or maybe you're just worried that you are getting nothing but coal this year.{} No worries, whether you are on the naughty or the good list, you can get free stuff!{} And lets be honest, who doesn't like free stuff?{} I know I do, which is why I'm bringing you some of the coolest free stuff you can get in the Lowcountry!{} Every Friday Ill give you the rundown on deals and steals you can find around town and this month, they're just in time for the holidays!
--WonderWorks ToyStoreThis offer is exclusively for ABCNews4 viewers.{} All you have to do is say the magic word "Wonderfuntastic" and receive a free gift with any purchase!{} This offer is good at the Belle Hall Shopping Center at 624 D Long Point Rd{}and West Ashley at 975 Savannah Highway, suite 107.{} So hurry in for your free gift, just in time for the holidays!{}
--Charleston Children's Boutique in West Ashley--- Want a free ornament?{} Well head on over to the Charleston Children's Boutique where you get a free ornament with any purchase every day in December!{} {}Located at 92 Folly Road Blvd.
--Mom and Pop Pop Up Shop downtown - Trying to buy local for the holidays and want the chance to do it all in one place?{} Where the Mom and Pop, Pop Up Shop{}at 359{}King Street in downtown Charleston{}is the place to be this holiday season!{} Every Thursday in December you can get free coffee and donuts just for stopping in to see what they have to offer!{}
--Free Starbucks--- Who wants some free coffee?{} I hear free coffee goes great at that holiday party you have been planning for months!{} Well head on over to Starbucks Friday, December 09 because they are giving away a free Via Ready Brew 3-pack with the purchase of 1lb of Christmas blend.{}
--Williams-Sonoma--- Worried that the turkey will be too dry, the pies will fall in, or the wine pairing is a little off for the big holiday dinner?{} For the domestic side in you, this is your chance to participate in a complimentary technique class on how to make a Holiday Feast!{} Its happening this Sunday, December 11 at the Williams-Sonoma store located at 281 King Street in downtown Charleston.{}
--Mount Pleasant MediSpa--- {}Trying to get perfect skin before that holiday party or do you want to give the gift of perfect skin this season?{} Look no further than this little spa tucked away in Mount Pleasant!{} December freebies include:{} Buy four facials, $200 value, and get one for free.{} Buy two microderms, $200 value, get one free.{} Buy two get one free of the Mt.P Lipgloss and then buy $100 in product and get two free facials and buy a Thermage service and get three free microderm facials.{} The MediSpa is located at{}999 Lake Hunter Circle, Unit D in Mt. Pleasant.


text:
CBS Sports Radio, heard on over 300 stations across the nation, will be broadcasting LIVE from the 79th annual NFL Draft at Radio City Music Hall in New York City. Night duo Chris Moore and Brian Jones of The Mojo Show, will be heard on-air, streaming online at www.cbssportsradio.com and through the Radio.com and CBS Sports apps for mobile devices from 6:00PM-12:00AM on Thursday, May 8, for round one of the draft and from 6:00-11:00PM on Friday, May 9 for rounds two and three. CBS Sports Radio overnight host Damon Amendolara will serve as reporter. Listeners can expect to hear the live announcements of the draft picks, player interviews and analysis.
Tune in to @CBSSportsRadio 5/8+5/9 to hear @MOJOonCBS & @DAonCBS from #NFLDraft @ @RadioCity; stream live coverage- www.cbssportsradio.com.
A full list of CBS Sports Radio stations can be found at http://radio.cbssports.com/stations/.


text: Sioux Falls Man Reports Theft of 4 Guitars By Gene Hetland May 2, 2014 A Sioux Falls man says someone got into his house one day this week and stole four guitars. Read More Category: Articles Tags: Grand theft, Guitars Send to a friend! Share on Facebook Share on Twitter Pin it! Reddit This! Share on Tumblr!


text:
Thunderbirds nip Silvertips 3-2
Justin Hickman beats Everett's Austin Lotz for a shorthanded goal in Seattle's 3-2 win (Christopher Mast)
By Andrew Eide
EVERETT — Friday night, in Everett, the Seattle Thunderbirds picked up where they left off before the holidays. Playing the first of two games against the Everett Silvertips, the T-Birds got a late second period goal by Sam McKechnie and relied on 36 saves from Justin Myles to steer home a 3-2 win against their rivals.
It was Seattle's (22-10-1-3) 10th win in their last 11 games and was a big one considering the clogged U.S. Division standings. Seattle played a strong opening period only to see the Silvertips control the second and had to hold on in the third to secure the win.
"There were parts I really liked about the game and then there were parts we've got to work on," Steve Konowalchuk said. "I thought in the first period we came out with the energy and passion that our team needs to play with and I think that probably ended up carrying us for the win."
Myles was the big story for the T-Birds as he made big save after big save to keep Everett (22-11-4-0) from taking a lead. As good as the goalie was, Seattle got a big save from an unlikely source late to get the win.
Everett got a late power play and pulled goalie Austin Lotz to create a six-on-four advantage. With just seconds left in the game the Silvertips crashed the Seattle net and Tyler Sandhu had the puck with a wide open T-Birds net. Sandhu took a shot and defenseman Evan Wardley flung his body across the slot to block the shot and preserve the lead.
"We got off to a good lead, they came out in the second, they weren't going to quit," Myles said. "Our team played well to the end, we really stuck with it…Wards with a big block at the end to save the game there."
The T-Birds built a lead after starting the game hitting everything in sight. Every shift it seemed like they were looking for a Silvertips player to hit. That set the early tone and the T-Birds were getting chances.
"That's our game," Konowalchuk said. "We have to play physical as a team. We've got some pretty good speed and pretty good size, we've got to use it."
They out shot Everett 13-10 in the first period and got on the board first.
While short-handed Justin Hickman stole the puck at his own blue line and was off to the races. Breaking in on goal he made a nice move to get Lotz going in the wrong direction and roofed a back hander for his 12th goal of the year.
The Silvertips pushed back and tied the game when Carson Stadnyk crashed in on net and beat Myles. Stadnyk scored and didn't stop, running over Myles, knocking the goaltender down and dislodging his mask. A scrum ensued and Stadnyk was assessed a penalty. Despite the hit, Myles was not rattled.
"I was OK," he said of the play. "Kind of lost my stick, I was kind of confused by that. It was in the far corner but I was OK. My teammates did a good job sticking up for me."
Seattle got their lead back five minutes later on a nice play by Alex Delnov who worked the puck up ice and hit a trailing Shea Theodore who got Lotz down and scored his 14th goal into an empty net.
The second period was not a good one for the T-Birds.
The Silvertips game is to clog up the neutral zone and force turnovers. They were able to dictate their style in the second and the T-Birds turned the puck over while struggling to get any consistent offensive pressure. Everett ended the period out shooting Seattle 15-4.
"As good as I liked our first I didn't like our second at all," Konowalchuk said. "I guess give them credit, they responded but we didn't manage the puck at all in the second period, turnovers put us on our heels. They're good at clogging the neutral zone that's why, when you get the opportunity to get it in when you get in the red, you've got to get it in, we didn't.
We did have time to get it in…but we shot ourselves in the foot in the second period."
By controlling the play Everett forced the T-Birds into a couple of penalties and tied the game when Jujhar Khaira fired home a rebound on the power play for the Silvertips.
Just when it looked like Everett was taking the game over the T-Birds got their lead back just before the second period horn.
Seth Swenson broke up an Everett pass in the Seattle end and headed up ice with McKechnie on a two-on-one break. He feathered a nice saucer pass to McKechnie who deked Lotz and scored what would be the game winning goal with 33 seconds left in the period.
Despite only getting four shots in the second, Seattle managed to get their one-goal lead back.
"No doubt about it, big goal," Konowalchuk said. "You know, they're coming on pretty strong, we needed some good goaltending there and to get a late goal…after not playing a good second to get another goal lead, that's definitely big."
Seattle managed to right the ship somewhat in the third and Myles, and Wardley, made all the stops needed to get the big win.
The win gave the T-Birds the same number of points as Everett in the Western Conference standings and now Seattle has a chance to move ahead with a win at home on Saturday. With both teams missing key players this becomes a huge stretch for both as the U.S. Division continues to be tough.
Both teams were missing important players. Everett was without leading scorer Josh Winquist who is nursing an injury. They also missed Manraj Hayer, to an injury, and defenseman Mirco Mueller who is at the World Junior Championships.
Seattle was without Connor Honey, Mathew Barzal, Ethan Bear, Jaimen Yakubowski and Keegan Kolesar. Konowalchuk said that they were optimistic that Honey was close to coming back and that Barzal was week-to-week.
The power play struggled for Seattle as they went 0-for-5 on the night.
Justin Myles picked up his first career win at the Comcast Arena in Everett last season. After the win Friday he is now 2-0 in that buildilng.
The game Friday was the eighth December game Seattle has played within the division. They have gone 7-1 in that stretch and will look to make it 8-1 Saturday night.
Everett is the WHL's best team when it comes to suppressing shots. They average just under 25 shots allowed a game and while it looked like Seattle was going to best that with 13 first period shots, they managed to keep it under their average. The T-Birds only managed eight shots in the final two periods for a total of 21 on the game.
Follow Andrew on Twitter @andyeide


text:
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Abu Dawood collected 500,000 hadith, but included only 4,800 in this collection. Sunnis regard this collection as fourth in strength of their Six major Hadith collections. It took him 20 years for collecting the ahadis. He made series of journeys to meet most of the foremost traditionists of his time and acquired from them the most reliable ahadis quoting sources through which it reached him. Since the author collected ahadis which no one ever assembled together, his sunan has been accepted as standard work by scholars from many parts of the Islamic world.
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text: Evie Vila dons her new year's glasses during the festivities in Tamaqua. Adding to the already festive event outside, residents of the ABC Hi-Rise in Tamaqua gathered during their annual New Year's Eve celebration held inside the building's community room. The event consisted of music, food and dancing. The event is held in conjunction with Tamaqua's annual New Year's Eve Eagle Rise.