text:
16 Insane But True Tinder Hook -Up A Reddit thread opened up to discuss some of the WARNING — some of these Tinder tales are NSFW so be careful reading in.
Rules 1. NSFW. If a post is exploiting a minor or contains any illegal imagery please report it to the mods either by clicking the report button or contacting us.
View photo. # tinder #fails # tinder after dark #afterdark # nsfw ; 2 years ago.
Sex: Reddit tinder nsfw
|Facts about rape
|Pretty women escorts
|10 things to say to a girl you like
|They start whispering about me and pointing at me. No memes or reactions allowed. This is a home for any and all nsfw pictures acquired through Tinder or from the relations through Tinder so that fellow redditors can enjoy either grotesque or beautiful images. You work with with what you have, reddit tinder nsfw. She throws a hiss fit that her phones dead and her parents are looking for her. The next time I saw her I got a blowjob whilst we watched Titanic…. Did I do it right?


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Change Currency
No inch overlooked.
Super soft 100% Combed Cotton
Lightweight Alpine White T-Shirt
No-feel discharge ink
Logo printing on side, sleeve, and upper chest.
Printed Label
Showing reviews 1-10 of 21 | Next
Posted by Junior Sepulveda on 9th Mar 2017
The quality of the sort is a+ not to mention the printing seems to hold up excellent in the wash. Great shirt to wear on a warm day, thin but durable. Definitely going to order plenty more from the LZ family. Shipped out fast and customer service is on point too. Got more stickers to know what to do with! Thanks again to having dope ass products at a reasonable price!
Posted by DragonTimmeh on 20th Jan 2017
I normally try and support my favorite Youtubers via direct donations or Patreon because 90% of the time the quality of their merch isn't worth the price.
I gave LZBMX a chance and ordered 2 shirts and a bunch of stickers (got a lanyard thrown in too which was awesome, thank you guys). The stickers lived up to the hype. Put a few on each of my bikes, went out for some rides. Came back and washed the bikes like I normally do and the stickers are holding up great. The quality of the shirts is amazing so far, super soft and very comfortable. I haven't washed them yet but they feel like they will hold up over time. One happy customer and will definately let my friends know.
Posted by Charlie Turner on 27th Dec 2016
One of the nocest Tees for your money only problem in the World of BMX is white things dont stay that color for too long so u might get a stain here or there.
Posted by Ursula on 22nd Dec 2016
My son loves the shirt. Cool for basic T, but be aware it will shrink. That was a plus for us because now the size is perfect. I have a happy kid!
Posted by ge on 22nd Dec 2016
I brought this shirt for my middle son, his older brother has one already, for Christmas. I can't wait to see his face.
Posted by Tracy on 20th Dec 2016
Great shirt bought for my son for Christmas can't wait to see his face
Posted by Unknown on 19th Dec 2016
The most comfortable and soft tshirt I have ever bought from and website.
Posted by Tim Helton on 23rd Sep 2016
LZBMX shirts are the most comfortable and vibrant shirts I own and theyre my favorite for that reason. Awesome product.
Posted by Trevor Peters on 19th Sep 2016
Love the quality just bought 3 more and the stickers are greater also 10 out if 10
Posted by Maria Mattox on 5th Sep 2016
Great quality shirt and shipping was very fast. Love Lzbmx and will buying more products.
Showing reviews 1-10 of 21 | Next

subset: commoncrawl


text:
If this is received well (please don't hate me), people can feel free to add things to the top of the page using the syntax in the source.
And Now, a Bit of Conceptual Birdsong / Discussion
Started by: WikidotThis is the discussion related to the wiki page And Now, a Bit of Conceptual Birdsong.
Date: 24 Mar 2013 11:20
Number of posts: 4
RSS: New posts
Date: 24 Mar 2013 11:20
Number of posts: 4
RSS: New posts
Pixeltasim 24 Mar 2013 11:56
I like this, especially the inclusions of normal ones. +1
Unfold by Pixeltasim, 24 Mar 2013 11:56
Roget 22 Jun 2013 22:48
I quite like this. It uses its unique format very well, and is just well-written all around. Good show.
Whether you like it or not, history is on our side. We will bury you!
I've written a tale upvoted by Djoric, Bright, Echo, Yoric, Moose, VAE and Voct, fite me irl if you don't respect


text:
Like magic, turn oranges into mini-bowls for sprightly salsa for a fun Halloween look.
Try using Monterey Jack or Pepper Jack cheese in place of the Cheddar cheese.
Save the leftover orange segments and eat them as a snack the next day.
© 2017 ®/TM General Mills All Rights Reserved


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For any questions related to Cvent, feel free to contact our Customer Care team.
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Existing epidemiologic evidence indicates that soyfood intake reduces risk of ovarian but only limited research has been conducted. To examine this relationship in detail, Chinese investigators conducted a case-control study involving 1,000 women (mean age, 59) from Guangzhou, the capital city of Guangdong Province of southern China.
Information on habitual consumption of soyfoods, including soybean, soymilk, fresh tofu, dried tofu, and soybean sprout, was obtained face-to-face from participants through a validated and reliable semi-quantitative food frequency questionnaire. Isoflavone intakes were then estimated using the USDA nutrient database. The ovarian cancer patients consumed on average much less soy than their healthy counterparts, 75.3 grams per day versus 110.7 grams per day. When divided women into tertiles, according to the amount of soy consumed, those in the highest intake group (≥120 grams per day) were 71% (odds ratio, 0.29; 95% confidence interval 0.20 to 0.42) less likely to have ovarian cancer than were women in the lowest intake group (<61 grams per day). Isoflavone intake was also inversely associated with the ovarian cancer risk, with significant dose-response relationships being noted.
Lee Andy H., Su Dada, Pasalich Maria, Tang Li, Binns Colin W., Qiu Liqian, Soy and isoflavone intake associated with reduced risk of ovarian cancer in southern Chinese women, Nutrition Research (2014), doi: 10.1016/j.nutres.2014.02.005.


text: Ted Miller Colorado coach Jon Embree got a late start with his 2011 recruiting class. That's not going to happen for the 2012 class. The Buffaloes received their third commitment on Thursday*from defensive tackle Tyler Henington of Mullen HS (Denver, Colo.). The 6-foot-5, 265-pound prospect had 104 tackles and 11 sacks for the state champion Mustangs as a junior. His father, Troy, was a defensive tackle for Texas Tech. It's notable that two of the Buffaloes' three pledges are from in-state. Embree probably wants to wrap up the local guys whose heart is with Colorado quickly, then focus outside the state, particularly in Southern California. We did a look at early commitments in the Pac-12 on Wednesday, and the Buffaloes are second only to USC (five) in early commitments. Originally posted by ESPN.com - Pac-10 Blog Click here to view the article.


text:
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Tips for minimising and effectively dealing with a food and beverage product recall
Shane O'Donnell
Leo Moore
Emily Comber


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understand yourself.
Some great places to start
online assessment tests are:
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The great option of Solo Cup Koozie
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text:
User:Yoshiyuki Murakami
From OpenWetWare
I am a new member of OpenWetWare!
Contact Info
- Yoshiyuki Murakami
- Tokyo University of Agriculture and Technology
- Address 1
- Address 2
- City, State, Country etc.
- Email me through OpenWetWare
I work in the Your Lab at XYZ University. I learned about OpenWetWare from When I searched iGEM information, I found this site., and I've joined because I'd like to communicate with iGEM team members..
- Year, PhD, Institute
- Year, MS, Institute
- Year, BS, Institute
Research interests
- Interest 1
- Interest 2
- Interest 3
Error fetching PMID 6947258:
Error fetching PMID 13718526:
Error fetching PMID 13718526:
- Error fetching PMID 6947258:
- Error fetching PMID 13718526:
leave a comment about a paper here
- Mark Ptashne. A genetic switch. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press, 2004. isbn:0879697164.


text:
Exhibitors may register for exhibit space using the online form or the Word form.
Reserve your space online here.
View the floor plan of the exhibit area including space that is already reserved.
Reserve furniture and download exhibit kit forms online or using the PDF version.
Platinum, Gold, and Silver sponsors should contact Andrea Massengile at firstname.lastname@example.com or 202-575-1875 to ask for the discount code to receive your booth credits.
FAQs about Exhibits
Q: Where will exhibits be located?A: Exhibits will be located in the Francis Scott Key Ballroom on the second floor of the Baltimore Hilton Hotel.
Q: What are the booth sizes?A: All booths are 8'x10'.
Q: What is the maximum number number we can reserve?A: There is a no maximum limit.
Q: What are the prices?A: Booths are $650 for ACP Members and $750 for Non-Members. Platinum, Gold, and Silver sponsors receive booth credits as part of their sponsorship commitment.
Q: What is the exhibiting schedule?A: The schedule is the following:
Q: What is the exhibitor cancellation policy?A: Cancellation refund requests must be made in writing. Send your written request to: Attn: Exhibit Cancellation, 4725 Dorsey Hall Drive, Suite A, PMB 709, Ellicott City, MD 21042. For written cancellations postmarked before or by January 1, 2014, a refund of 50% of the exhibit registration fee will be given. For notifications postmarked after January 1, 2014, no refund will be given.
9/6/2017ACP Board of Directors Meeting
9/7/2017 » 9/8/2017September 2017 ACP Membership Meeting
4/6/2017ACP Announces Finalists for 2017 "Excellence in Publishing Awards"
3/29/2017ACP Welcomes Keynoter Thad McIllroy to 2017 Membership Meeting
5/17/2016Mercy Dominates as Theme of 2016 ACP Excellence in Publishing Awards
5/18/2015ACP Announces Winners of the 2015 Excellence in Publishing Book Awards


text:
This stunning girl is LUNA! *courtesy post-contact Francisco Flores at 323-580-3042 for adoption info
Luna was born 12/07/2012, I adopted her on March 2012. She has current vaccines, spayed and microchipped. She is a loving and sweet pitbull. Luna grew up with my daughter and has been great with kids and people. She loves other dogs but has rarely had interaction with cats and other pets. She is not house trained. Luna spends all her time burning energy in a 5k sq foot yard. She understands basic commands (sit, stay, and lay down) (laying down is not her favorite). Luna is great at walking she is leashed train but sometimes has a tendency to pull when excited. Please let Luna show you what a fabulous dog she is!
âContact Francisco Flores at 323-580-3042 or via email at email@example.com to meet Luna!
Website: www.icaredogrescue.org
Facebook: www.facebook.com/ICARE.rescue
0-6 months: $350
7-12 months: $300
12+ months: $250
$50 more for pure bred dogs.
Adoption fee includes :
Shots up to date of adoption
Spay/neuter (if old enough)
We also require to stay second on the micro-chip info for life and have a life time return policy on all our rescue dogs adopted out.
Unfortunately, we do not adopt out of state under any circumstances. We recommend that you visit your local shelter or dog rescues in your area if you are looking to adopt.
Thank You!
Your message has been sent to I.C.A.R.E. Dog Rescue.
You'll receive a copy, too, at to help you keep track of which pets you've inquired about, and which shelters and rescues you've emailed.
NOTE: Some shelters have physical locations you can visit; some of these shelters may only have pets for a limited time, so please do not wait for a reply—just go visit the shelter! Other organizations are rescue groups run by busy volunteers who may take a while to reply. You can find information about the shelter or rescue group caring for this pet, and their adoption procedures, on the pet's details page on Adopt-a-Pet.com.
Contact this Rescue Group about ZZ-Luna *courtesy post again.


text:
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> Mothers NuLens Headlight Renewal Kit
Mothers NuLens Headlight Renewal Kit
Restore headlights to crystal clear perfection!
Mothers NuLens Headlight Renewal Kit powers through oxidation on plastic headlight lenses to restore clarity and function. With an electric drill, Mothers NuLens Headlight Renewal Kit polishes headlights and other hard plastics. In minutes, you can take years off the appearance of weathered headlights. Mothers makes it easy!
Mothers NuLens Headlight Renewal Kit includes:
Mothers PowerBall 4 Lights
Mothers PowerBall 4 Lights is a foam ball that attaches to your electric drill. Instead of polishing small surfaces by hand, you can get them done faster and with better results with the PowerBall. This patent-pending detailing tool is made of professional grade foam that is soft and highly absorbent. It polishes out oxidation, scratches, and discoloration to restore a smooth, clean surface. The PowerBall 4 Lights attaches via hook and loop to the included drill backing plate.
The spherical shape of the Mothers PowerBall 4 Lights allows you to use all sides when polishing in case one area becomes soiled. Unlike flat pads, you get more surface area and can therefore complete the job faster. Keep turning the foam ball to use a clean surface. The foam tabs that compose the ball are able to move over alignment dowels (small bumps on the lens cover) without ripping or snagging.
5 Restoration Pads
The Mothers NuLens Headlight Renewal Kit includes five single-sided sanding pads. These pads are designed to be used on severely oxidized headlight lens covers if the Powerball and PowerPlastic did not achieve satisfactory results.
One pad is 800 coarse grit. The second pad is 1500 fine grit. The third pad is 3000 grit. Start with the least aggressive pad that will be effective on the plastic. Then use finer and finer pads until you achieve a very finely scuffed surface that feels almost smooth. Next you'll use the Mothers PowerBall 4 Lights and Mothers PowerPlastic to restore smoothness and clarity to the lens cover. With all the options in Mothers Powerball 4 Lights Lens Restoration Kit, you will be equipped to restore just about any plastic headlight or taillight.
Mothers PowerPlastic Plastic Polish
PowerPlastic features a special blend of
oxidation-inhibiting polymers, UV shields and an ultra-fine polish
that work in unison to clean and clarify your headlights, taillights, convertible top windows and more. When used in combination with a PowerBall and your electric drill, PowerPlastic removes oxidation and surface scratches with ease, and it leaves a transparent coating to protect plastics.
Use Mothers NuLens Headlight Renewal Kit to polish out light oxidation and mild swirls on all hard plastic headlight lens covers and other hard plastic surfaces.
The Mothers NuLens Headlight Renewal Kit works with a standard electric drill. No polisher is needed to get great results!
Clean, clear headlights allow more light to pass through the lens, therefore providing you with a better view of the road. Restore the look and function of your vehicle's headlights with the simple, effective Mothers NuLens Headlight Renewal Kit.
Kit includes:
Mothers PowerBall 4 Lights
Drill Adapter
5 Restoration Pads
8 oz. Mothers PowerPlastic
Mothers NuLens Headlight Renewal Kit
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| Mothers NuLens Headlight Renewal Kit |
Mothers PowerCone Polishing Tool
Mothers PowerMetal Scratch Removing Polish
Mothers PowerPlastic 4Lights
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Mothers Professional Rubbing Compound 12 oz.
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Mothers Leather Cream Moisture-Rich Conditioner
Mothers Professional Instant Detailer 24 oz.
Mothers Professional Rubbing Compound 128 oz.
Mothers NuLens Headlight Renewal Kit
Stars based on
Orlando, FL
5 Stars
I would recommend this item to a friend.
Mothers NuLens
November 8, 2016
Product worked well to restore the plastic on my auto lens cover. My auto is ten years old so there was extensive discoloration and pitting.Wet sanding was necessary to restore the lens finish. Lens looks like new.
Tom K
Chicago suburbs
4 Stars
I would recommend this item to a friend.
Great kit
September 1, 2016
Great kit
Fresno, CA
5 Stars
I would recommend this item to a friend.
February 25, 2016
My brother did my headlights for me and they look like new. Love how they look, can't believe the difference. Highly recommend. He said it was super easy to do.
Townsville Qld Australia
5 Stars
I would recommend this item to a friend.
Better than expected
September 11, 2015
Worked great. I took my time just over an hour all up. Time well spent. Easy enough to do I can now drive at night
More sand paper
christopher tower
paducah ky.
5 Stars
I would recommend this item to a friend.
NuLens headlight kit
January 4, 2015
works great ! you have got to take your time when doing the sanding step's with the pads , I found that it works great bi using bleach water as you rinse while your sanding an had gone over the lens several times in each step as my own reinsurance that I did a good even job , both headlight look like new to me compared to what they look like before , I tried several other products in the past that I had just wasted my money on , MOTHERS has proven to be the best to me ! this product has saved me over $180.00 that would have cost me for 2 new headlight lens assembly's on my FORD EXPLORER .
should include more of the sanding disk, than just for one vehicle .... :)
Stoneham, MA
4 Stars
I would recommend this item to a friend.
Works pretty well
July 13, 2014
Tried out on my son's 20 year old Accord. Lens were moderately cloudy, and were noticeably clearer after just buffing. Gonna try wet sanding to get scratches out of my 06 Civic headlights.
works reasonably well after just buffing, but don't expect "like new" results. Have not tried wet sanding yet.
Victor Von Aspern
Pinole, Calofornia
4 Stars
Headlight Renewal Kit
July 5, 2014
It removes the yellow color but will not provide a shine to theplastic cover It removes the yellow color but does not provide a shine to the plastic light cover. The cover still looks foggy although I tried to polish it for over an hour.
Will remove yellow color.
Will not polish the lens.
Nick E
5 Stars
Great product
June 10, 2013
I've always been skeptical of headlight cleaners, but I tried this on my sister's 2003 Toyota Celica GTS that has lived it's entire life outside in the harsh sun of the Southwest. The headlights were hazed to the point of not putting out very much light, but it was light surface oxidation, and did not require heavy sanding. I simply used strong pressure with the powerball mounted to a corded drill and the included polish. Excellent results.
5 Stars
Worked Great
April 20, 2012
I live in Sarasota, Fl and the sun is brutal. My headlights were tarnished bad and I was amazed at how well this product worked. I had to sand and use the power ball. They are close to original. Amazing, I give it 5 stars.
Tara S.
5 Stars
Awesome Results!
February 20, 2012
I was a little skeptical at first, but WOW, this product is absolutely amazing. My lights were horribly yellow and hazy. They look brand new thanks to Mothers. A must buy!!!
5 Stars
Really works!
July 29, 2011
I noticed my son's 2000 Grand Am's headlights were blocked after he told me he couldn't tell the difference between the high and low beams. I couldn't even see the bulbs inside the headlight cover. I ordered the Mother's Powerball 4 headlights. At first, when I put it on, I was pretty light with the drill. It made a little difference but then I started to press harder with the drill. What a difference then! WOW! Excellent product! very impressed
Pt Cruiser
5 Stars
Excellent product!
May 7, 2011
Used on a 2002 Pt Cruiser that had very clouded & yellow headlights. The outcome was amazing! I didn't even have to use the sanding pads. Just make sure you have an extra battery on hand if using a cordless drill as it wears it down fast! Very pleased with product! Thanks mothers
5 Stars
April 23, 2011
Used on my girlfriends 1996 BMW 328i, e36 BMWs are notorious for clouded headlight housings and hers had NEVER been touched since it was made. This stuff took it back to looking 99% brand new. ITS INCREDIBLE and FAST. HIGHLY RECOMMEND.
R Isaacs
2 Stars
March 31, 2011
guess wont work on headlights over 11 years old tryed it even the extrem messures all i got was a smooth lense nothing at all noticable good thing i got it on sale
3 Stars
yellow lights
May 23, 2010
Worked very well on the inner, smaller lamps, but not so well on the main head lamps. Granted that I'm pretty sure that they have never been treated in 12 yrs. The light shines through much better, but there is still a yellow hint on the lamp.
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It's not that easy being gold.
Tara Lipinski, who won the Olympic gold medal for ladies singles figure skating in 1998 at the age of 15, appeared ...
Read Whole Story
It seems like a nice problem to have; a gifted child with a seemingly promising future. But when -- and how much -- should a parent get involved? And when should they get out of the way?
Get top stories and blog posts emailed to me each day. Newsletters may offer personalized content or advertisements. Learn more.


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Quote:Ok so what is this one if not a golden laced Wyandott?
I have 2 that look like this and one that look like this one below and they look to me like different breeds but I'm new to chickens still trying to learn😊
Oh and I think that other color your seeing on the polish wing if that's what you are referring to is dirt here is a pic of her when she was about a week old.
Edited by ashleynicole - 10/10/15 at 1:37pm


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WileyFox wants to challenge Samsung with the Swift 2 and Swift 2 Plus
10 Major New Features Apple Announced Today At The iPhone 7 Event
Red Bull's World's First Escape Room Championship and what it's about.
Vodafone continues to release their own branded devices with the latest Smart Ultra 7 Android-powered smartphone.
GoPro Just Launched A Bunch Of New Things Including A Drone
Nokia Lumia 1520 Unboxing – Video, white Nokia Lumia 1520. Windows Phone 8 Black


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Pathogen Survival, Toxigenic Growth, Microbial Spoilage, Cascade Effects, Intrinsic Stability, Hurdle Technology, Extrinsic Effect, Predictive Modelling and Quantitative Microbial Risk Assessment
Microbial Shelf Life Assurance Testing by Premier Analytical Services can build the confidence you need in your product's safety and quality throughout shelf life.
Maintenance of product safety and quality throughout shelf life is the aim of all food producers.
Deterioration due to microbial activity can be a major threat to both the quality and safety of most food products. It is therefore essential that a systematic approach is taken to the determination of product shelf life.
Microbial shelf life assurance testing provides the fundamental information to confirm and conclude a microbial risk assessment. It is the most effective way to validate controls designed to maintain product integrity. And, if time is an issue we have analytical models that can avoid impractical lengthy assessments.
We can offer 4 types of microbial shelf life assurance testing:
Microbial shelf life assurance testing by premier analytical services can help you to determine, challenge and extend the shelf life of both new and existing products.
|What is it?
|Microbial evaluation of a products ability to achieve its desired shelf life under the specified storage conditions. Either to validate that the target shelf life is achievable or to verify that it can be achieved by the working practises in place.
|How is it performed?
|The product is manufactured under typical conditions. Microbial test suites, customised for each product based on a predictive microbial risk assessment, are performed at regular intervals throughout the product's entire target shelf life.
|When do you do it?
|Normally performed at NPD trial stage. It is best used when the microflora is inherent in the product or where the environmental flora is well understood and unlikely to vary.
|Builds confidence in the products ability to achieve its intended microbial stability under specified storage conditions by examining the effect of natural microflora.
|Relies on the presence of natural flora at a single production time point so it is specific for the conditions of manufacture at the time the test batch was made. It does not challenge the potential variation in microflora that may be present. As such it does not provide a robust challenge of a products microbial stability as determined by its intrinsic and extrinsic factors.
|What is it?
|A positive challenge of the microbial stability of both product and production process.
|How is it performed?
|The product is inoculated with a cocktail of stress-conditioned microorganisms selected by predictive microbial risk assessment. Sub lethal stress conditioning develops the inherent strength and stability of the organisms such that they survive introduction to the new environment and provide the most robust challenge. The microbial tests performed at regular intervals are customised to detect those microorganisms present in the inoculum.
|When do you do it?
|At NPD stage to establish shelf life for new products or to extend shelf life of existing products. Especially useful if time constraints prohibit evaluation across entire target shelf life.
|Provides robust information to complete a microbial risk assessment. Not often required to last for the full duration of target shelf life. The likely period over which growth and death would be seen can be estimated as part of the predictive microbial risk assessment and meaningful evaluations obtained which when extrapolated negate any requirement for impractical lengthy assessments.
|Negative controls are required. These can however double up as shelf life validating tests.
|What is it?
|Evaluation of the microbial stability of both product and production process under adverse conditions.
|How is it performed?
|Typically either intrinsic, extrinsic or both parameters are altered. The altered 'abuse' state will be well controlled and compared to standard state.
|When do you do it?
|When customer abuse may be an issue or to investigate product and process issues.
|Provides insight into product performance under worse case scenarios.
|May not be indicative of shelf life attainable under normal conditions.
|What is it?
|Physically altering an extrinsic parameter, such as storage temperature, in order to assist agents of product deterioration.
|How is it performed?
|Most often storage temperature is maintained at a higher level with the aim of improving microbial growth kinetics.
|When do you do it?
|When shelf life evaluation is required within a reduced timeframe compared to the target shelf life.
|Application restricted to scenarios wherein product intrinsics are thermo-stable and the hazard organisms are known to occur at low temperature but their growth kinetics are increased at elevated temperature such that an early warning can be given regarding product stability.
|The alteration of an extrinsic parameter gives a false representation of the product profile such that intrinsics may change. The potentially problematic microbial population may not be suited to development in this altered environment such that resultant lack of growth could impart a false sense of security. Additionally cascade effects at lower temperature could be missed.


text: Paper Information Journal: AVICENNA JOURNAL OF PHYTOMEDICINE (AJP) 2017 , Volume 7 , Number 1; Page(s) 54 To 65. Paper: GINGER EXTRACT MODULATES THE EXPRESSION OF IL-12 AND TGF-βIN THE CENTRAL NERVOUS SYSTEM AND SERUM OF MICE WITH EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS Author(s): JAFARZADEH ABDOLLAH*, AHANGAR PARVIN REYHANE, NEMATI MARYAM, TAGHIPOUR ZAHRA, SHAMSIZADEH ALI, AYOOBI FATEMEH, ZUHAIR MOHAMMAD HASSAN * DEPARTMENT OF IMMUNOLOGY, MEDICAL SCHOOL, RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES, RAFSANJAN, IRAN Abstract: Objective: The main function of IL-12 is differentiation of naive T cells intoTh1 cells and TGF-b is a powerful immunoregulatory cytokine. The immunomodulatory and anti-inflammatory properties of ginger have also been reported in some studies. The aim of this study was to evaluate the effects of ginger extract on the expression of IL-12 and TGF-b in a model of experimental autoimmune encephalomyelitis (EAE).Materials and Methods: EAE was induced in C57BL/6 mice by immunization with myelin oligodendroglial glycoprotein emulsified in complete Freund's adjuvant. The mice were administered intra-peritoneally with ginger extracts or PBS, from day+3 to+30. On day 31, mice were scarified and the expression of IL-12 and TGF-b mRNA in the spinal cord were determined by using real time-PCR. The serum levels of cytokines were measured by ELISA.Results: In PBS-treated EAE mice, the expression of IL-12 P35 and IL-12 P40 mRNA in the CNS and the mean serum levels of IL-12 were significantly higher than those of healthy group (p<0.001). In ginger-treated EAE mice, the expression of IL-12 mRNA and its serum levels were significantly lower as compared to PBS-treated EAE mice. No significant difference was observed between PBS-treated EAE mice and healthy group regarding the expression of TGF-b mRNA. In ginger (300 mg/kg) -treated EAE group, the expression of TGF-b mRNA and its serum levels were significantly higher in comparison to PBS-treated EAE mice (p<0.01 and p<0.05, respectively).Conclusion: These results indicated that ginger extract modulates the expression of IL-12 and TGF-b in CNS and serum of EAE mice. Keyword(s): EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS, GINGER, IL-12, TGF-β, SERUM Printable Version


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ZoologyZoology, or Animal Biology, is a very diverse field involving the study of organisms as a whole, and how they interact to create the ecosystems that are visible (and invisible) in the environment around us. Zoology encompasses a wide spectrum of topics, ranging from animal behaviour to their genetics, with conservation and paleobiology playing equally important roles. Research into these areas includes building robotic jellyfish and deciphering the communication of insects!
Articles about zoology
Subscribe to unanswered questions that interest you by clicking the icons in our articles
We see birds around us every day, so you might think we know all there is to know about our feathered friends - but that is far from the case!
Delve deeper into birds
Despite its amazing ability to explain how species change and diverge there are some areas of evolution that scientists are still working to understand.
Delve deeper into evolution
Sharks are one of our most poorly understood animals, hard to study, dangerous and diverse, impacting the ecosystem and sometimes our daily lives.
Delve deeper into sharks
Specialised articles...
Blog posts about zoology
Our blog posts are often written by scientists about their ongoing research
Squid Lady Parts
Thursday 31st of July 2014
Mass Extinction
Saturday 9th of February 2013
Why do we yawn?
Sunday 18th of November 2012
Open Questions in Embryo Development
Wednesday 17th of October 2012
How many species are there?
Sunday 19th of August 2012


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Satyam Computer has declined to entertain requests by its former directors to insulate them from any loss or legal expenses associated with cases they might face.
The company has said it was prohibited from "indemnifying the former directors until they are adjudged not guilty in any proceedings".
Satyam, which is being revived under its new owner Tech Mahindra with help from central government, said that the Ministry of Corporate Affairs has clarified that the company is prohibited from advancing defence costs to its directors and officers until they are acquitted or proved innocent.
"Certain independent directors of the company have demanded indemnification for any loss and advancement of fees and expenses associated with cases and other proceedings and investigations that may be instituted against them on the basis of the indemnification agreements entered into by them with the company," Satyam said while disclosing its financials for the October-December 2008 quarter.
"The company has denied a request for advancement of legal costs as it is prohibited by virtue of Section 201 of the Companies Act, 1956 from indemnifying the former directors until they are adjudged not guilty in any proceedings," it said.


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|JSB Healthcare
Back Pain can be really annoying, especially when they become chronic and makes it difficult for you to move around. JSB bring to you a special professional full back massager: JSB HF43 Full Back Massager with heat which will take care of your back pains with specialized and dedicated massage modes for upper and lower back. This back kneading massager is a hit since its launch online in India.Long Hours at the office chair and driving back from office can be killing for a back, which is not exercised much. If you are sitting in your office for long hours, it is common to have lower lumbar pain. This ache can only grow and travel up your spine to make it worse for your cervical area. Such pains can be caused due to lack of blood circulation in the lumbar/spine column.An effective back massage can help you overcome this pain and discomfort. This full back massager can be used in cars as well, as it is compatible with 12V charger.


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SIGG top - active base top
Separate base for active bottle tops with SIGG drinking mechanism.
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Available for orders over $75
Buying this product = 9 Reward points for Members. Your cart will total 9 points = voucher of $0.45. Not a Member? Join at checkout to claim these points.
Customer ratings and reviews


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Category — ALL RECIPES
{recipe} Slow Cooker Pumpkin, Lentil, & Chickpea Curry
We have had an unusually cold and wet winter here in Northern California. I have found myself turning to this recipe again and again as a hearty, healthy, easy way to warm up myself at dinner – and have leftovers for lunch the next day.
This recipe is incredibly easy and hands-off, and as a bonus it is also vegan. I often find vegan food to be lacking in that certain je ne sais quoi, but this curry is universally enjoyed by just about everyone I've served it to, and has great flavor and depth without a lot of effort. [Read more →]
January 27, 2017 No Comments
{recipe} "Frozen"-Themed Meringue Trees
My son is obsessed with all things Anna, Elsa, and Olaf! He loves the movie Frozen so when we wanted to make meringues, we decided to give them a little bit of Frozen flair by coloring them pale teal with snowy sprinkles.
December 26, 2016 No Comments
{adventures in gingerbread} The French Quarter, New Orleans – in Gingerbread
Behold: New Orleans' French Quarter, made entirely of gingerbread and candy!
For the past several years I've gotten together with a group of friends to make a crazy gingerbread project. (See bottom of the post for links to all of the previous projects!) This is actually last year's project, which I thought I'd share now in hopes I can get it together in time this year to share our upcoming project. The project is always related to the theme of our Christmas party, which was "Christmas in the French Quarter."
December 14, 2016 1 Comment
{recipe} Easy Cake Mix Christmas Cookies
Did you know you can make super easy and tasty cookies out of cake mix? Well, now you do! And you can dye them green and decorate them with red sprinkles to make them holiday-ready.
December 12, 2016 1 Comment
{recipe} Spicy Mexican Chocolate Tequila Balls (in the style of Bourbon Balls)
Every Christmas, my brother-in-law Steve requests a batch of bourbon balls like his grandma used to make. The original recipe for this old-fashioned holiday treat calls for crushing up nuts, Nilla wafers, powdered sugar and cocoa and moistening them with bourbon and corn syrup. They are no-bake and super easy to make, but the problem is, nobody in our family likes them but him! So this year I decided to shake up tradition a little bit and incorporate some of his other favorite things into the recipe, like tequila, dark chocolate, cinnamon, and chipotle powder, in hopes of getting a few more takers.
December 5, 2016 2 Comments
{secret chef tips} Here Is All The Thanksgiving Advice I Have to Offer
It probably won't surprise you to hear that a lot of people ask me for advice about cooking Thanksgiving dinner. But why keep it to my inner circle? Here, in pretty much random order, are the resources, advice, and tips I have to make your Thanksgiving cooking successful!
November 18, 2016 1 Comment
{recipe} Soft Pumpkin Spice Cookies with Brown Sugar Glaze
Pumpkin spice season – amirite? Now I have never been a big fan of pumpkins in my lattes, oreos, tampons, and so forth… but a delicious fall cookie? That is what pumpkin was made for.
These soft pumpkin cookies are super cake-y and tender, with a decadent brown sugar glaze, and I basically can't stop eating them and now I've negated all the working out I did today but that's beside the point. Because PUMPKIN SPICE!
October 3, 2016 1 Comment
{recipe} Creamy White Bean Stew with Parmesan and Greens
My husband has been flirting with the idea of going vegetarian, and while I don't think us meat-lovers will ever get all the way there, it is fun to try and incorporate more vegetarian and almost-vegetarian dishes into our regular dinner repertoire. This one is a new favorite, with slow-braised white beans, kale, arugula, and spinach. It's a definite winner!
The stew is flavored by a bit of bacon, a tiny amount of anchovies, and a parmesan rind. This is like an umami trifecta! If you're worried about the anchovies being fishy, don't: they just add a nuttiness and a complexity to the finished dish. To make it vegetarian, just omit the bacon and anchovies.
September 28, 2016 No Comments
{recipe} The Only Chocolate Buttercream Frosting Recipe You Need
Can we talk about chocolate frosting for a minute? When it's good, it's the best – but so often, it's not that good. Too fudgy, too dark, too sweet, too thick, too sloppy, too chocolatey, not chocolatey enough… you get the idea. But this one, to me, is simply perfect. It's what I hope for when I bite into a cupcake. And it is really easy to achieve at home.
The recipe is roughly the chocolate buttercream they use at Magnolia Bakery. The texture, taste, and sweetness are absolutely perfect. It is chocolatey, buttery, and sweet in all the right amounts. And it is super smooth and silky to boot. I have given amounts for different-sized cakes below, so you can make enough for what you need. [Read more →]
September 13, 2016 No Comments
{recipe} Baked Blackberry Buttermilk Donuts
I got a donut pan for my birthday and have been experimenting with baked donut recipes like crazy. When I've tried standard flavors like chocolate and vanilla, I've been disappointed, frankly, because they aren't fried like "real" donuts. But stacking the batter up with fresh berries changes the game completely. This is a cakey, muffin-y kind of donut that you can't stop eating. Dipping them in a simple blackberry glaze just before serving makes them a near-perfect weekend breakfast treat.
July 19, 2016 No Comments


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The Train star is remarkably shining once more in 2012 as this artist's performances will take place in many locations. Train is considered one of those artists that continually amaze admirers, and give every concert a magical touch to be unlike the preceding and take the attendee to a universe of absolute delight. You might perhaps don't believe that, though if you have the chance to book Train tickets and be on time to one of the performances, you will realize what we are talking about.
Surely, you don't need us to tell you who's Train, yet what you perhaps ignore is that Train Concert Boston in December concerts deserve being gone to and primarily Train tickets TD GARDEN 2012. All you need behind having Train tickets is to go straight to the event to feel the happiness of being a concerts lover and join Train society, of which you already take part. Train is not like any performer, but a great star whose reputation exceeds the boundaries, and the performer's admirers are counted by thousands all over the world, yet they do not all have your luck to be on time to the event like you, but what's uniting you is zeal you all have for Train.
Train is going to stop at many locations like . And if you choose to attend one of them, for instance you are going to share instants of happiness with groups of Train admirers. In addition, if you are wondering what showgrounds Train concerts are going precisely to stop at, we may state . However, major Train December 2012 concerts are very attended also in and many other locations.


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Free personalized radio that
plays the music you love
Features of This Trackelectronica influences
extensive vamping
minor key tonality
groove based composition
prominent synth drums
an instrumental arrangement
and many other similarities identified in the Music Genome Project
These are just a few of the hundreds of attributes cataloged for this track by the Music Genome Project.show more
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No "I see monstas" or "over it"
But still, nice song
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Drake Channels Taylor Swift For New Apple Music Ad
Drake stars in the new Apple Music commercial ©Twitter/Apple music
Drake is Taylor Swift's biggest new fan, if Apple Music is to be believed.
The rapper stars in a new commercial for the streaming service which sees him rocking out to the US singer's track "Bad Blood," ending with him getting so into the tune that he loses focus and falls off the weights bench.
The commercial, which premiered last night during the American Music Awards and has since been shared by Apple on Twitter, links back to an ad that debuted earlier this year in which Swift fell off a treadmill when rapping along to Drake's hit "Jumpman."
First Published: November 22, 2016, 7:09 AM IST


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Clinical Significance of Eosinophilia in HIV-infected Individuals
Introduction.—Eosinophilia is a common finding in patients with AIDS. However, there is no research linking this eosinophilia to specific causes, such as parasitic infections or drug reactions. The clinical significance of and factors associated with eosinophilia in HIV-infected subjects were examined retrospectively.
Methods.—The study included 42 patients with HIV infection and peripheral eosinophilia. They were matched for the date at which absolute eosinophil counts were first more than 500 cells per cubic millimeter and for CD4 cell counts with 84 patients infected with HIV but without eosinophilia. Clinical factors potentially associated with eosinophilia were compared between the 2 groups.
Result.—The patients with eosinophilia had a median CD4 cell count of 26 cells per cubic millimeter, reflecting late-stage HIV infection. Fifty-two percent of patients with eosinophilia were black, compared with 18% of controls. The case patients were also more likely to have pruritus (50% vs. 20%), and a physician-documented rash (76% vs. 52%). Patients with eosinophilia were more likely to have specific cutaneous diseases, such as eosinophilic folliculitis, atopic dermatitis, and prurigo nodularis. Allergic reactions, parasitic infections, cancer, and adrenal insufficiency—all factors commonly associated with eosinophilia—were no more common in case patients than in controls.
Conclusions.—The finding of peripheral eosinophilia in patients with AIDS is linked to cutaneous diseases. However, it is not associated with allergic reactions, parasitic infections, or other conditions frequently associated with a raised eosinophil count. Thus, the finding of asymptomatic
eosinophilia in a patient with AIDS with cutaneous disease is not an indication for an extensive diagnostic workup.
• In this study, peripheral eosinophilia in individuals infected with HIV was associated with low CD4 cell counts and a high incidence of cutaneous diseases, especially eosinophilic folliculitis and atopic dermatitis. There was no increased incidence of parasitic diseases, drug reactions, collagen vascular disorders, and neoplasms, which are other conditions typically associated with eosinophilia.
UVB Phototherapy Is an Effective Treatment for Pruritus in Patients Infected With HIV
Purpose.—Many patients with HIV infection have chronic, intractable pruritus. A common cause of this problem is eosinophilic folliculitis, although generalized, severe pruritus may occur without primary skin lesions. A number of different treatments have been tried. Ultraviolet B (UVB) phototherapy was evaluated for use in the treatment of HIV-related pruritus that did not respond to other treatments.
Methods.—The study included 21 male patients with HIV infection and intractable pruritus that did not improve with topical corticosteroid or oral antihistamine therapy. Fourteen had eosinophilic folliculitis, and 7 had primary pruritus. All patients had a CD4+ cell count at the time of UVB phototherapy or within 30 days and were able to undergo treatment on a regular basis. The patients received UVB phototherapy 3 times a week, with physician examination after every fifth treatment. Pruritus was scored on a scale of 0-10, with 10 representing severe pruritus.
Results.—At the start of treatment, the patients' mean CD4 count was 91 cells per µL. Pruritus scores were significantly improved by UVB phototherapy, from a mean of 8.6 to 2.2. Improvement peaked after a mean of 21 treatments, at a cumulative UVB dose of 3,399 mJ/cm2. The results were similar in patients with eosinophilic folliculitis and primary pruritus.
Conclusions.—For patients with HIV-related pruritus, UVB phototherapy can offer significant symptom reduction and improvement in quality of life. The results are consistent with previous studies of UVB phototherapy for eosinophilic folliculitis. This study also shows a favorable response in patients with eosinophilic folliculitis.
• Pruritus in HIV-infected individuals is extremely common and is often severe. Ultraviolet B phototherapy can be a less expensive alternative to psoralen plus ultraviolet A for treating these patients. Although exposure to ultraviolet radiation can be associated with viral activation, previous studies have shown that there is no consistent alteration in CD4 positive cell counts or HIV-1 viral load in patients treated with phototherapy.
Efficacy and Safety of Desensitization With Sulfamethoxazole and Trimethoprim in 48 Previously Hypersensitive Patients Infected With Human Immunodeficiency Virus
Objective.—Sulfamethoxazole-trimethoprim is the first-line approach to primary prevention of Pneumocystis carinii pneumonia and Toxoplasma infection in HIV-positive patients. However, adverse skin reactions are a major problem. These reactions can be managed by treatment throughout the duration of hypersensitivity, rechallenge, or desensitization. Desensitization with sulfamethoxazole-trimethoprim was studied for safety and efficacy in a large cohort of HIV-infected patients. Clinical and biological factors associated with success were evaluated as well.
Methods.—The prospective study included 51 HIV-infected patients with a history of allergy to sulfamethoxazole-trimethoprim, including rash or other cutaneous adverse reactions. These reactions were blamed on sulfamethoxazole-trimethoprim if they occurred within 21 days after the start of treatment, or later if there was no other potentially responsible drug. The study excluded patients with life-threatening reactions, involvement of more than 1 mucous membrane, urticarial rash, or cutaneous rash occurring within 6 weeks before enrollment. It did not exclude patients with fever, pruritus, or involvement of just 1 mucous membrane, however. Desensitization was a 2-day procedure, with the full dose of sulfamethox-azole-trimethoprim (400 and 80 mg, respectively) being reached on day 3. For 3-months after desensitization, the patients were monitored for cutaneous reactions attributable to sulfamethoxazole-trimethoprim. If treatment had to be interrupted during that time, desensitization was considered to have failed. If sulfamethoxazole-trimethoprim was well tolerated after 3 months, desensitization was considered a success. There were 48 evaluable patients.
Results.—At 3 months, 77% of patients were taking sulfamethoxazole- trimethoprim without problems. Daily treatment continued for a median of 16 months. The failure rate was 23%, with 8 of the 11 failures occurring on the first or second day. Desensitization was more likely to be successful in patients with lower CD4+ cell percentages and CD4+-CD8+ ratios.
Conclusions.—Successful desensitization with sulfamethoxazole-trimethoprim in hypersensitive HIV-infected patients is reported. This study achieved a 77% success rate, compared with the 33% to 96% success rates of previous studies. The duration of desensitization does not appear to affect the success rate. It remains to be determined whether rechallenge or desensitization is the best approach for patients with non-life-threatening reactions to sulfamethoxazole-trimethoprim. Although the failure rates are comparable, desensitization may be safer than rechallenge.
• Previous desensitization schedules have been of varying durations, ranging from 5 hours to 20 days and have differed greatly with regard to inclusion criteria, the mode of dose escalation, and the success rate. Desensitization is not entirely safe, and anaphylactoid reactions have been observed.
Oral Hairy Leukoplakia in 71 HIV-Seropositive Patients: Clinical Symptoms, Relation to Immunologic Status, and Prognostic Significance
Background.—Oral hairy leukoplakia occurs almost exclusively in men with HIV infection. Although its presence indicates moderate to advanced immunodeficiency, its value as a marker of prognosis is not known. These investigators evaluated oral hairy leukoplakia as a prognostic marker in HIV patients with oral hairy leukoplakia and in HIV patients without this development.
Methods.—A total of 456 patients with HIV-associated skin disease were identified; 71 of these had oral hairy leukoplakia (15.6%; 65 men, 5 women, and 1 transsexual; median age 35 years). Oral hairy leukoplakia was diagnosed when a lesion had the characteristic appearance, did not rub off, and did not respond to anticandidal drugs. Subpopulations of CD4+ T lymphocytes were measured at baseline and regularly thereafter and survival time was calculated starting with the diagnosis of oral hairy leukoplakia.
Findings.—The 71 patients with oral hairy leukoplakia most often had lesions on the lateral tongue that were white or gray-white, well-defined, adherent plaques with a "hairy" texture. In 60% of these patients the lesions were bilateral; in 1 patient lesions covered the dorsal surface of the tongue; and in 1 patient lesions were found on the buccal mucosa. Coexisting skin diseases were frequent and included oral candidiasis (71% of patients), seborrheic dermatitis (55%), folliculitis (34%), Kaposi's sarcoma (27%), and herpes zoster (21%). Most patients had significant immunosuppression at the time of diagnosis of oral hairy leukoplakia; 75% had CD4+ T lymphocyte counts less than 354/µL, and more than 50% had already had an AIDS-defining opportunistic infection diagnosed. The entire group of patients with HIV infection and the subgroup of HIV patients with oral hairy leukoplakia were stratified according to their CD4+ T lymphocyte count at diagnosis. For all patients who had CD4+ T lymphocyte counts of 300/µL or more at diagnosis, HIV patients with oral hairy leukoplakia had a significantly shorter median survival time (25 months) than the group as a whole (52 months).
Conclusions.—Patients with HIV typically have advanced disease by the time their oral hairy leukoplakia is diagnosed. Other investigators have demonstrated that oral hairy leukoplakia is a marker of progression to AIDS. In this study, the only prognostic significance of oral hairy leukoplakia was in patients whose CD4 + T lymphocyte counts were 300/µL or more at diagnosis; these patients had half the estimated survival time as patients with HIV but without oral hairy leukoplakia. The lesions of oral hairy leukoplakia were well characterized clinically and almost always appeared on the lateral tongue.
• The finding of oral hairy leukoplakia in patients with HIV infection indicates advanced immunosuppression. Even in patients with relatively high CD4 T lymphocyte counts, oral hairy leukoplakia is associated with a poor prognosis.
In Situ Polymerase Chain Reaction-based Localization Studies Support Role of Human Herpesvirus-8 as the Cause of Two AIDS-related Neo¬plasms: Kaposi's Sarcoma and Body Cavity Lymphoma
Introduction.—It has been suggested that human herpesvirus 8 (HHV- 8), a new herpesvirus, may be the cause of Kaposi's sarcoma (KS) and body cavity B-cell lymphoma in patients with AIDS. If HHV-8 is the cause of these 2 AIDS-associated tumors, it should be detectable in the earliest clinical lesions. It also should localize to specific target cells in a pattern that reflects the tumorigenic pathways. The localization of HHV-8 in early patch stage KS lesions is reported.
Methods.—The study analyzed 21 biopsy specimens of patch stage KS lesions. In situ polymerase chain reaction (PCR) was performed, with and without simultaneous immunostaining. Normal skin from healthy subjects was studied as well.
Results.—None of the control specimens showed any HHV-8 DNA by either PCR or in situ PCR. All PCR-positive specimens showed distinct, specific in situ PCR staining. In 4 patch stage KS lesions, in situ PCR staining localized to nuclei of endothelial cells and perivascular spindleshaped tumor cells. Later stage KS lesions, that is, plaques and nodules, showed further positive cells, including epidermal keratinocytes and eccrine epithelia. Specific HHV-8 infection of endothelial cells, KS tumor cells, and epithelioid pneumocytes also were detected in pulmonary KS. Dual staining of body cavity B-cell lymphoma showed HHV-8 in malignant tumor cells but not in reactive lymphocytes.
Conclusions.—The findings show temporal and spatial associations between HHV-8 and the AIDS-related neoplasms KS and body cavity B-cell lymphoma. More definitive studies are needed to determine how widespread HHV-8 is in the population, and whether it is the true cause of KS.
• These authors report that HHV-8 can be found in early patch stage lesions of KS, where they are localized to endothelial cells and spindle-shaped tumor cells. In advanced lesions, the virus can be found in other cells as well. Similarly, in body cavity-based B-cell lymphoma, HHV-8 is present in malignant tumor cells and not in reactive lymphocytes. These findings support a causal role for HHV-8 in the pathogenesis of these 2 AIDS-related conditions.
AIDS-related Kaposi's Sarcoma: Prospective Validation of the AIDS Clinical Trials Group Staging Classification
Introduction.—Cancer staging systems were designed for the planning and evaluation of treatment and as indicators of prognosis. Unique challenges are presented in staging Kaposi's sarcoma in persons infected with HIV type 1 (HIV-1). A proposed staging system for AIDS-related Kaposi's sarcoma was developed in 1988 that classified patients into poor-risk or good-risk groups on the basis of tumor extent and immune system status. To validate this system, staging and survival data were collected on patients enrolled in clinical trials for Kaposi's sarcoma sponsored by the AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases. An analysis of this system and potential refinements are presented.
Methods.—In 294 patients, AIDS-associated Kaposi's sarcoma was staged according to tumor extent, severity of immunosuppression, and other systemic HIV-1-associated illnesses. These patients were observed for survival. For each variable according to published criteria by the AIDS Clinical Trials Group, the patients were classified as at good risk or poor risk. To evaluate the association between the variables and survival, univariate and multivariate analyses were performed. To improve the predictive value of the staging system, additional analyses were conducted.
Results.—For each of the variables, survival was significantly shorter for patients in the poor-risk category. For patients in the good-risk category of tumor extent, median survival was 27 months, and in patients in the poor-risk category it was 15 months. For severity of immunosuppression, patients in the good-risk category had a median survival of 40 months and those in the poor-risk category had a median survival of 13 months. For other systemic HIV-1-associated illnesses, patients in the good-risk category had a median survival of 22 months, and those in the poor-risk category had a median survival of 16 months. The most predictive information was severity of immunosuppression. Significant additional predictive information in patients whose immune function was least impaired was provided by tumor extent. A simplified model resulted by using a CD4 count of 150/µL rather than 200/µL.
Conclusion.—In patients with AIDS-related Kaposi's sarcoma, survival can be predicted with this classification system. The most predictive information was found with CD4 count and tumor stage. Better discrimination between prognostic groups was found by using a lower CD4 count than originally proposed.
• In patients with relatively high CD4 counts, tumor extent added significant prognostic information. This provides a strong rationale for the treatment of early Kaposi's sarcoma in these individuals. The staging system presented here may be further refined by inclusion of other variables that may more accurately reflect Kaposi's sarcoma or HIV-1 biology, such as viral load, markers of immune activation, or more specific poor-risk tumor features.


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Free Websites to Watch Cartoons Online: Watching cartoons, never gets boring, whether you are a child or fully grown up adult. Tom Jerry to Pokémon Go, excites everyone. These cartoons take you down the memory lane of the golden era of your childhood and you forget everything around you.
So get time, grab some cheesy popcorn and explore these websites to replenish the beautiful part of your childhood.
8 Best Sites to Watch Online Cartoons
1. Cartoon HD Download
If you lost the track of your favorite cartoon or want to watch some particular episode, then this website cartoon hd download will serve your purpose.
Though it has login id button, but one need not have to register to watch.
A navigation bar is given just below the header on which, you can choose one from anime genres, cartoons, movies, etc.
It also lists the genre of cartoons, so that you can watch according to your taste and explore some new cartoons which you always missed.
2. CartoonsOn
It is not like an ordinary website with those boring toolbar to choose from. That why it is listed favorite among all. You can search your favorite cartoon by character and even watch movies on cartoons. The site is simple and interactive with minimal options to easily choose from.
3. WatchCartoonOnline
Colourful, vibrant and with loads of memes makes this site special. Ignoring the ads, you get a list of cartoons, all displayed on one screen and thus making you confused. You will really think for a while, which cartoon to watch first. It stores of the best cartoons that were lost with time.


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Introducing Karaoke Fridays at The Dog Hotel.
We'll be singing every Friday from 9:00 pm til late!
We'll be making things all the more fun by handing out free drink cards to the most entertaining singers!
To top things off, best in show will win a $50 food voucher.Book your table now!


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Mark as Urgent
This one is based on a darkly comic short story written by John Clerkin - it's an excellent vignette about a disgruntled gardener for a future corporation. I'm trying to convince him to have a stab at doing a graphic version - the only problem is that the story would almost need to be told in reverse
I start out meaning to do a more comic-style, and just keep fiddling with it. The fore-shortened perspective was to try and make it more claustrophobic, but I don't think it's worked out - I think it's too busy. Still, that's an hour
Posted on July 9th, 2008 |


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Posted: February 09, 2017|
At Synergy Brewing Systems, our Pro Pilot Brewing Systems are the best available. Our 15 gallon and 26 gallon systems are great for intermediate to advanced homebrewers, but not every run needs to capitalize on the full capabilities of these systems. In fact, there are quite a few benefits to doing small batch runs every once in a while.
Posted: January 11, 2017|
At Synergy Brewing Systems, we love homemade, hand-crafted homebrews, but one of the main issues facing homebrewers is what to do with all the spent material left over from a run. Understanding the importance of sustainability and the value that spent grain still has after use in homebrewing, we compiled this list of better ways to use your grain than just simply throwing it out.
Posted: December 14, 2016|
What makes a great homebrew? A lot of it has to do with attention to detail. Although there may not be one "right" way to brew, here are some crucial aspects of the brewing process to keep in mind for your next homebrew.
Posted: November 07, 2016|
Whether it's a hobby, an obsession or a way of life, homebrewing is important to a large group of people and its popularity has only increased with time. The reason why homebrewing is so satisfying is arguably because making something by hand and seeing others enjoy the fruits of your labor is of one the best feelings in the world. And if it turns out good, it's that much better! For those as curious as us, here's more about the rise of homebrewing.
Posted: October 03, 2016|
At the first hint of crispness in the air, we all know that summer has come to an end and fall has arrived. May it be Oktoberfest, football season or for us homebrewers, hop harvest season, fall is associated with beer and it's no surprise that fall beers are some of the most popular today. Here are some reasons why we feel fall and beer go so well together.
Posted: July 04, 2016|
Now that summer is finally here it's the perfect time to brew up a Saison and to experiment around with some of the warmer temperature preferring yeast strains. One of my favorite summertime yeast strains is the French Saison Yeast strain. This is a very versatile yeast strain that can handle the summer heat. In fact it loves it!
Posted: March 16, 2016|
By Aaron Brussat
Have you ever wondered why you should control the temperature of your fermenting beer? Any humble brewer will tell you, "I don't make beer; I make wort. Yeast makes beer." While that is true, one of the final steps in brewing a batch is also the most vital to control: fermentation. Yeast health, pitch rate, and temperature will all affect the way your beer tastes; we'll just focus on temperature here. While most commercial breweries have glycol-jacketed fermentors they can control to the degree, homebrewers are often left to their wits to finagle ways to keep temperature in check.
Posted: February 11, 2016|
First things first, what constitutes a craft beer? Well, it depends on which group/association you adhere to, The Brewers Association or the Craft Brew Alliance. Both make concessions to different breweries, both have differing criteria and it can be tough to know who to listen to. The generally accepted rule for qualifying as a craft beer, is you can't produce more than 2 million barrels of brew per year, which the Brewers Association recently increased to 6 million barrels. Here are a couple of articles that go much more into detail about these craft beer imposters.
Posted: November 09, 2015|
1. Marzen/Oktoberfest:
Back before we had refrigeration to help in the brewing and storing process of beer, there weren't many summer ales being brewed. Most brewers ended their runs with the onset of spring, and began again in the fall. Most of those being brewed in March, which is where the term Marzen comes from. Marzen/Oktoberfest beer is rich, full-bodied and usually dark copper in color with a mid-high ABV%. The Munich Oktoberfest beer that most of us know and is served at the Munich Oktoberfest is typically 5.0-6.0% ABV with a mild hop profile.
Posted: September 14, 2015|
Hop Pellets:
Hop pellets are highly processed hops consisting of finely powdered hop cones compressed into small tablet forms. Even though they look commercialized you can use them in home and commercial brewing applications. One thing hop pellets have going for them is by weight they are 20%-30% stronger than the same type of hop in loose form. These concentrated little pellets are first processed to remove the non-resinous materials in the hops, thus reducing the weight and volume of the hops. Most hop pellets are made form a blend of hops to maintain consistent alpha acid levels.


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Squirrels enter your home by traveling along electrical or cable wires or jumping from limbs that are near the home. They also enter through chimneys, attics, holes in siding and vents without screens. The squirrels damage siding, wiring, insulation and household items. Gnawing on wood or other substances wears down the squirrels teeth. Determining if you have squirrels inside your walls is not a difficult task if you know the signs to watch for.
Things You'll Need
- Flashlight
Listen for a scratching noise inside your walls. Gray squirrels are often active during the day, while flying squirrels are active at night.
Climb up into your attic when you hear the scratching noise. Use a flashlight to look down into the wall near where the noise is coming from. This may enable you to locate the squirrels and nest. While you are in the attic, look around for squirrel droppings. They are brown, oval, smooth and approximately 1/2-inch long. If the problem is flying squirrels, the droppings will be in a pile.
Inspect the lower and upper exterior of your home for chewed holes. This is evidence of a squirrel infestation, particularly if you spot greasy rub marks or claw marks in the area as well. Pay close attention to areas near vents or where wires or plumbing enter your home. These are most likely the entry points.
Check your home and attic for damage to wood or insulation. Squirrels chew through just about any material, but this type of damage is often seen along their pathway.
Tips & Warnings
- Prune limbs that are within 5 or 6 feet of your home. This prevents them from entering via this source. Another effective method is to slit a 24-inch plastic PVC pipe. Slide it onto cable or electrical wires; it spins when a squirrel attempts to walk across it, thus causing the pest to lose its footing. Contact the power or cable company before attempting the PVC method.
- It is important to get rid of the squirrels. They may die and create an offensive odor for weeks. Hire a professional exterminator if you cannot get rid of them yourself.
- Don't attempt to remove a squirrel yourself. They have a powerful bite and may be dangerous. Call a professional once you are certain squirrels are inside your walls.
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Olivia Hussey
In drama school since the age of four, and professionally acting at 13, Hussey didn't actually become famous until she was 16 when she was chosen out of 800 girls as Juliet in Franco Zeffirelli's "Romeo and Juliet" in 1968. She followed up with a supporting role in a minor British film.
But although she was such a sensation is both the UK and the US, her marriages and divorces were sticky business. There are conflicting reports about the dates of her marriage to Dino's son, Dean Paul Martin. Either way, they divorced in 1978. She soon married British pop star, Paul Ryan, whom she'd been briefly engaged to ten years before. After that divorce, she was married to another singer, Akira Fuse from '80 to '87, and then again in '91, this time to hard rocker David Eisley of the group Dirty White Boy. She has three kids-sons by Martin and Fuse, and a daughter by Eisely.
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You can now get the Google Nexus S 4G for only a c-note. (Of course, with a 2-year contract.) Not bad considering it's our favorite Sprint phone—you're guaranteed the latest software updates as soon as they're available. [TechCrunch]
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Kinja is in read-only mode. We are working to restore service.


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text: FAIRBURN, Ga. | Willie Clarence Harris, age 30, of Fairburn, Ga., formerly of the Whitfield Community in York, died April 1, 2006 in Whitfield. Services will be 1 p.m. Saturday at the Sumter County High School Auditorium in York with Rev. O.L. Sealy officiating. Burial will follow in Black Bluff Cemetery with McInnis Mortuary of Livingston directing.


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BCHFH Local Mission Statement:
Building on our Christian foundation by working with people of all faiths and beliefs in a spirit of collaboration and compassion, Blount County Habitat for Humanity, along with our ReStore, mobilizes community partners and volunteers in the building, rehabilitation and repair of safe, quality and affordable housing and the promotion of homeownership as a means to breaking the cycle of poverty.
Blount County Habitat for Humanity is known in our community for our vision to eliminate poverty housing and homelessness by providing a simple, yet quality and energy efficient home to families and individuals living below 60% of the area median income level in Blount County. And, as evidenced by the most recent U.S. Census, the demand in East Tennessee is great: of the over 125,000 persons living in Blount County, 17,000 (13.7%) live below the poverty line. Habitat offers a "hand up" for low-income families, giving their children the opportunity to grow up in a safe, stable and comfortable housing environment.
During the year, we have two application cycles where we have 100 families per cycle apply for homes through the program. Since 1992, Blount County Habitat has built 144 homes, housing about 213 adults and 328 children. Each home appraises between $120,000 and $150,000, with the majority of the labor being provided by volunteers from the community.
Each partner family attends nine months of homeownership and financial literacy classes and contributes 300-450 hours of "sweat equity" by building their home and the homes of other partner families. After their home is constructed, the partner family is responsible for repaying a zero-interest mortgage at an affordable rate.
In an effort to meet the public demand for high efficiency, low energy homes, Blount Habitat has begun making affordable "green" upgrades in existing and new homes when financing allows. Making low-income homes more energy efficient will help to reduce energy bills, improve comfort and help to protect the environment. These are improvements for the homeowner and for the community.
Another important mission that makes a huge impact in our community is our Housing Repair, Rehab and Neighborhood Revitalization programs. Last year, BCHGH (HRC) provided over 90 repairs to Blount County residents (this year's numbers may even be higher!) who are our lower to very low income, or simply have a special need for a ramp. This repairs, sometimes critical in nature, can be life-changing to the resident. As with all our programs, we need funding and volunteers to support the continuation of our missions.
About our ReStore
The ReStore is a venture of Blount County Habitat for Humanity and supports the local affiliate by providing good stewardship of sustainable resources in the community. The mission of the Blount County Habitat for Humanity ReStore is to resell donated items to raise money to support the work of Blount County Habitat for Humanity and provide simple, affordable homes for families in need in Blount County. Items sold at the ReStore are donated by individuals, builders, manufacturers and local businesses. All proceeds from the ReStore go back into new construction, housing rehabs and housing repairs. The ReStore also benefits the community by diverting waste from local landfills and providing quality merchandise to our customers at reasonable prices. Shoppers can find clothing, household items, appliances, furniture, electronics, building supplies and MUCH more at the ReStore! It is easy for anyone to get involved at the ReStore! You can help your community and Blount County Habitat for Humanity by simply shopping at the ReStore, donating items you no longer need, or volunteering your free time!
For more information click over Blount County Habitat for Humanity, go to or contact Leslie Woodall


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A website is a highly useful tool as part of your business marketing strategy and works well when supported by the more traditional printed materials used to promote your business.
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Pens are too light, take a chisel to write. That's not original, but this lucid report is. A summary should be engraved, at least, on the office walls of all auditors, merchant bank advisers and company directors, and of any budding financier with ambitions to play the next takeover boom.
To begin with, it defies belief that the auditors, Spicer & Pegler, could sign off the accounts for so long of a company that the inspectors concluded probably never made a profit in its entire life. Yet the firm calmly concluded that the reported profits were a true and fair view. Do auditors earn their fees, or do they just sign for them?
Spicer was admittedly not working in the easiest of circumstances. The inspectors say that just before Atlantic's flotation the firm was deliberately deceived by the late John Foulston and by Vernon Davies, co- founders, about the proportion of lease contracts containing options to give up computer equipment.
These were the costly time-bombs that brought the company down. Spicer reported that the 'walk' contracts amounted to 5 per cent of leasing business, a figure that went in the prospectus for the flotation, sponsored by Rothschilds, which was also deceived.
But it was not just the advisers who were made fools of. So were the listing rules, the Stock Exchange and an entire army of investors. And the issue was not just one wildly misleading figure, but an entire method of accounting for profits and future liabilities that the inspectors tear to ribbons in the report.
They clearly believe the methods approved at Atlantic should never have been allowed in the first place. Caveat emptor is right up to a point, but investors deserve far better of advisers and auditors, especially when so many of them have crawled over a company for so long.
If Atlantic was a gigantic rip-off from beginning to end, the foolhardiness of B&C's board in taking it over is spelled out in gory detail.
They were victims in a way of their own propaganda, of years in which they had been praised as brilliant deal makers. John Gunn was just that in his early moneybroking years, when he really knew what he was talking about, and his image was reinforced by a disarming lack of personal pretension.
But the runaway boom and low interest rates of the Lawson era must have made him and his colleagues feel they could walk on water.
As the inspectors say, there was inadequate inquiry into Atlantic by B&C 'due in part to a lack of clarity as to what was expected of those retained to advise B&C, principally BZW, a merchant bank, and Outram Cullinan & Co (OC&C), a firm of strategy consultants'.
Each minimises its involvement, and claims reliance on others, the report says. 'In the evidence before us there was particular dispute as to the proper role and functions of BZW.' That has led to a pounds 600m lawsuit against BZW and countersuits have followed.
The inspectors say: 'Neither BZW nor OC&C recognised the perilous position of Atlantic, but OC&C produced material which should have given B&C warning that Atlantic's reported profits, and the statements made by Atlantic during the course of takeover negotiations, should be approached with considerable caution. Those warning signs, however, went unheeded by B&C'
The conclusion is that B&C acquired Atlantic without a proper understanding of its business, its accounting policies or its leases. 'The subsequent failure of Atlantic illustrates the high risks in seeking growth through the acquisition of quoted companies, particularly in a field in which the acquiror has little experience.'
Your starter for 10: list a dozen other 1980s glamour stocks that have gone the same way, with their inner flaws brought into the open by the bust that followed the Lawson boom.
And once bought, B&C failed to exercise effective stewardship, even though the cause of the collapse was present at the time of the takeover, the inspectors say.
One lesson from the B&C Atlantic saga is that fraud and outright personal greed do not have to be at the heart of something that goes wrong. Ambition, yes, but the inspectors are satisfied that John Gunn, Peter Goldie and Andrew Ashman were acting in what they perceived at the time (but erroneously, say the inspectors) to be in the best interests of B&C. 'They did not act dishonestly in the sense of seeking to defraud any person, or to acquire a benefit for themselves in the course of their dealings with Atlantic and B&C'
In a way, that makes the whole episode still more tragic for those involved. But while they brood, the report should prompt a much wider soul-searching among auditors.
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Dynasty is a cock slut
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- Kategorie: Amateur
- Ansichten: 4,027
- hinzugefügt: vor 5 Jahren
- Beschreibung: Dynasty is a thick and juicy black honey whose trunk is packing some extra junk This cock slut with a bubble butt is happy to suck on a thick, black cock while her pussy gets fingered and dickslapped. She gets fucked and fucked again before taking a dou
- Tags: black, facial, cumshot, threesome, tattoo
- Pornostars: Pornostar hinzufügen
- Favoriten von: 10
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