text:
Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking some of the blood flow to the tumor. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving everolimus together with temozolomide and radiation therapy may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of everolimus when given together with temozolomide and radiation therapy in treating patients with newly diagnosed glioblastoma.
Brain and Central Nervous System Tumors
Drug: everolimus
Drug: temozolomide
Radiation: radiation
Phase 1
Phase 2
|Study Type:
|Study Design:
|Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|Phase I/II Evaluation of Everolimus (RAD001), Radiation and Temozolomide (TMZ) Followed by Adjuvant Temozolomide and Everolimus in Newly Diagnosed Glioblastoma
- Maximum Tolerated Dose (MTD) of everolimus (RAD001) in combination with temozolomide (TMZ) and 3D-conformal radiotherapy (RT) or intensity-modulated radiotherapy (IMRT) followed by adjuvant TMZ with or without RAD001 (Phase I) [ Time Frame: Up to 49 days ] [ Designated as safety issue: Yes ]
- Survival at 52 weeks (Phase II) [ Time Frame: at 52 weeks ] [ Designated as safety issue: No ]
- Response rate (Phase II) [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]
- Time to progression (Phase II) [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]
- Progression-free-survival at 6 months (Phase II) [ Time Frame: at 6 months ] [ Designated as safety issue: No ]
|Study Start Date:
|March 2009
|Primary Completion Date:
|January 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Everolimus (RAD001), Radiation (RT), Temozolomide (TMZ)
Patients receive oral everolimus and oral temozolomide and 3D-conformal radiotherapy or IMRT as in phase I. Patients will undergo a 4-6 week rest period in course 2 and then proceed to adjuvant therapy.
Adjuvant therapy with everolimus and temozolomide (courses 3-8): Patients receive oral everolimus and oral temozolomide as in phase I.
Adjuvant therapy with everolimus alone (courses 9 and all subsequent courses): Patients receive oral everolimus as in phase I.
All patients undergo fludeoxyglucose (FDG)- or fluorothymidine-labeled PET/CT scans at baseline and periodically during treatment.
|Drug: everolimus Drug: temozolomide Radiation: radiation
Show Detailed Description
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Histologically confirmed diagnosis of 1 of the following:
- Glioblastoma multiforme (grade 4 astrocytoma)
Other grade 4 astrocytoma variants (e.g., giant cell)
- No grade 4 oligodendrogliomas or oligoastrocytomas
- Gliosarcoma
- Newly diagnosed disease
- Measurable disease ≥ 1 cm³ (phase I patients only)
- Some patients may be registered on protocol NCCTG-947252
- No oligodendrogliomas or oligoastrocytomas
Inclusion criteria:
- ECOG performance status 0-2
- ANC ≥ 1,500/μL
- Hemoglobin ≥ 9.0 g/dL
- Platelet count ≥ 100,000/μL
- Total bilirubin ≤ 2.5 x institutional upper limit of normal (ULN)
- Serum total cholesterol < 350 mg/dL
- Serum total triglycerides < 400 mg/dL
- AST ≤ 2.5 x ULN
- Creatinine ≤ 1.5 x ULN
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use effective contraception during and for 60 days after completion of study therapy
- Must be willing to undergo 2 mandatory research PET or PET/CT scans (all MCR and MCJ patients in phase I and MCR only patients in phase II)
- Must be willing to abstain from eating or drinking grapefruit or grapefruit juice during study treatment
- Must be willing to follow a diet low in fat and cholesterol while taking everolimus
- Must be willing to have imaging scans submitted for central review
- Ability to understand and willingness to sign a written informed consent
Exclusion criteria:
- Other active cancers requiring therapy to control disease or prior cancer diagnoses which pose a greater than 30% risk of death within the next 2 years
- Gastrointestinal tract disease resulting in an inability to take oral medication or a requirement for IV alimentation, prior surgical procedures affecting absorption, or active uncontrolled peptic ulcer disease
Uncontrolled intercurrent illness including, but not limited to, any of the following:
- Ongoing, uncontrolled, or active (acute or chronic) infection or disorder
- Symptomatic congestive heart failure
- Unstable angina pectoris
- Cardiac arrhythmia
- Psychiatric illness/social situations that would limit compliance with study requirements
- Severely impaired lung function
- Uncontrolled diabetes (fasting serum glucose > 2 x ULN) OR diabetes that would interfere with the performance of the FDG-PET/CT or FDG-PET scans
- Liver disease (e.g., cirrhosis, chronic active hepatitis, chronic persistent hepatitis, or history of hepatitis B)
- Known HIV positivity
- Positive hepatitis B antigen (HBsAg) or hepatitis C serology (HCV) tests
- Any history of allergy or intolerance to dacarbazine (DTIC)
- Significant traumatic injury within the past 21 days
- Severe allergy to sulfa medications
- Inability to tolerate levofloxacin with dapsone or pentamidine (inhaled or IV)
Inclusion criteria:
- At least 1 week, but no more than 6 weeks since prior surgical resection or biopsy
- Must comply with antibiotic prophylaxis with either trimethoprim/sulfamethoxazole (daily or 3 times per week), oral dapsone (daily) combined with daily levofloxacin, or monthly pentamidine (inhaled or IV) combined with daily levofloxacin
Exclusion criteria:
- Prior chemotherapy for any brain tumor
- Prior temozolomide or mTOR inhibitor therapies
- Any prior cranial radiotherapy
- Planned immunization with attenuated live vaccines ≤ 7 days prior to and during study period
- At least 21 days since prior major surgery (excluding neurosurgical biopsy, resection of brain tumor, or treatment of immediate post-neurosurgical complication [e.g., intracranial hematoma])
- Concurrent or prior treatment for this cancer with any other investigational agents
- Concurrent enzyme-inducing anticonvulsants (EIACs) or other strong inducers of CYP3A4 (i.e., carbamazepine, phenytoin, phenobarbital/primidone, rifabutin, rifampin, or St. John's wort)
Concurrent therapeutic doses of warfarin
- Low molecular weight heparin is allowed
- Concurrent systematic leukocyte growth factors (e.g., G-CSF or GM-CSF), except for the treatment of severe neutropenia
- Concurrent drugs or substances known to inhibit or induce CYP3A
- Other concurrent chronic treatment with immunosuppressive agents except dexamethasone
- Other concurrent anticancer agents
- Concurrent live vaccines
Please refer to this study by its ClinicalTrials.gov identifier: NCT00553150
Hide Study Locations
|United States, Arizona
|Mayo Clinic Scottsdale
|Scottsdale, Arizona, United States, 85259-5499
|United States, Connecticut
|Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
|Hartford, Connecticut, United States, 06105
|United States, Florida
|Mayo Clinic - Jacksonville
|Jacksonville, Florida, United States, 32224
|United States, Idaho
|Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center
|Boise, Idaho, United States, 83706
|United States, Illinois
|Illinois CancerCare - Bloomington
|Bloomington%, Illinois, United States, 61701
|St. Joseph Medical Center
|Bloomington, Illinois, United States, 61701
|Graham Hospital
|Canton, Illinois, United States, 61520
|Illinois CancerCare - Canton
|Canton, Illinois, United States, 61520
|Illinois CancerCare - Carthage
|Carthage, Illinois, United States, 62321
|Memorial Hospital
|Carthage, Illinois, United States, 62321
|Eureka Community Hospital
|Eureka, Illinois, United States, 61530
|Illinois CancerCare - Eureka
|Eureka, Illinois, United States, 61530
|Galesburg Clinic, PC
|Galesburg, Illinois, United States, 61401
|Illinois CancerCare - Galesburg
|Galesburg, Illinois, United States, 61401
|Illinois CancerCare - Havana
|Havana, Illinois, United States, 62644
|Mason District Hospital
|Havana, Illinois, United States, 62644
|Illinois CancerCare - Kewanee Clinic
|Kewanee, Illinois, United States, 61443
|Illinois CancerCare - Macomb
|Macomb, Illinois, United States, 61455
|McDonough District Hospital
|Macomb, Illinois, United States, 61455
|Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
|Moline, Illinois, United States, 61265
|Moline, Illinois, United States, 61265
|Illinois CancerCare - Monmouth
|Monmouth, Illinois, United States, 61462
|OSF Holy Family Medical Center
|Monmouth, Illinois, United States, 61462
|BroMenn Regional Medical Center
|Normal, Illinois, United States, 61761
|Community Cancer Center
|Normal, Illinois, United States, 61761
|Illinois CancerCare - Community Cancer Center
|Normal, Illinois, United States, 61761
|Community Hospital of Ottawa
|Ottawa, Illinois, United States, 61350
|Oncology Hematology Associates of Central Illinois, PC - Ottawa
|Ottawa, Illinois, United States, 61350
|Cancer Treatment Center at Pekin Hospital
|Pekin, Illinois, United States, 61554
|Illinois CancerCare - Pekin
|Pekin, Illinois, United States, 61603
|CCOP - Illinois Oncology Research Association
|Peoria, Illinois, United States, 61615
|Oncology Hematology Associates of Central Illinois, PC - Peoria
|Peoria, Illinois, United States, 61615
|Methodist Medical Center of Illinois
|Peoria, Illinois, United States, 61636
|OSF St. Francis Medical Center
|Peoria, Illinois, United States, 61637
|Illinois CancerCare - Peru
|Peru, Illinois, United States, 61354
|Illinois Valley Community Hospital
|Peru, Illinois, United States, 61354
|Illinois CancerCare - Princeton
|Princeton, Illinois, United States, 61356
|Perry Memorial Hospital
|Princeton, Illinois, United States, 61356
|Illinois CancerCare - Spring Valley
|Spring Valley, Illinois, United States, 61362
|United States, Indiana
|St. Francis Hospital and Health Centers - Beech Grove Campus
|Beech Grove, Indiana, United States, 46107
|Reid Hospital & Health Care Services
|Richmond, Indiana, United States, 47374
|United States, Iowa
|McFarland Clinic, PC
|Ames, Iowa, United States, 50010
|Bettendorf, Iowa, United States, 52722
|Cedar Rapids Oncology Associates
|Cedar Rapids, Iowa, United States, 52403
|Mercy Regional Cancer Center at Mercy Medical Center
|Cedar Rapids, Iowa, United States, 52403
|Siouxland Hematology-Oncology Associates, LLP
|Sioux City, Iowa, United States, 51101
|Mercy Medical Center - Sioux City
|Sioux City, Iowa, United States, 51102
|St. Luke's Regional Medical Center
|Sioux City, Iowa, United States, 51104
|United States, Kansas
|Cancer Center of Kansas, PA - Chanute
|Chanute, Kansas, United States, 66720
|Cancer Center of Kansas, PA - Dodge City
|Dodge City, Kansas, United States, 67801
|Cancer Center of Kansas, PA - El Dorado
|El Dorado, Kansas, United States, 67042
|Cancer Center of Kansas - Fort Scott
|Fort Scott, Kansas, United States, 66701
|Cancer Center of Kansas-Independence
|Independence, Kansas, United States, 67301
|Cancer Center of Kansas, PA - Kingman
|Kingman, Kansas, United States, 67068
|Lawrence Memorial Hospital
|Lawrence, Kansas, United States, 66044
|Cancer Center of Kansas, PA - Liberal
|Liberal, Kansas, United States, 67901
|Cancer Center of Kansas, PA - McPherson
|McPherson, Kansas, United States, 67460
|Cancer Center of Kansas, PA - Newton
|Newton, Kansas, United States, 67114
|Cancer Center of Kansas, PA - Parsons
|Parsons, Kansas, United States, 67357
|Cancer Center of Kansas, PA - Pratt
|Pratt, Kansas, United States, 67124
|Cancer Center of Kansas, PA - Salina
|Salina, Kansas, United States, 67401
|Cancer Center of Kansas, PA - Wellington
|Wellington, Kansas, United States, 67152
|Associates in Womens Health, PA - North Review
|Wichita, Kansas, United States, 67208
|Cancer Center of Kansas, PA - Wichita
|Wichita, Kansas, United States, 67214
|CCOP - Wichita
|Wichita, Kansas, United States, 67214
|Via Christi Cancer Center at Via Christi Regional Medical Center
|Wichita, Kansas, United States, 67214
|Wesley Medical Center
|Wichita, Kansas, United States, 67214
|Cancer Center of Kansas, PA - Winfield
|Winfield, Kansas, United States, 67156
|United States, Michigan
|Saint Joseph Mercy Cancer Center
|Ann Arbor, Michigan, United States, 48106-0995
|CCOP - Michigan Cancer Research Consortium
|Ann Arbor, Michigan, United States, 48106
|Oakwood Cancer Center at Oakwood Hospital and Medical Center
|Dearborn, Michigan, United States, 48123-2500
|Green Bay Oncology, Limited - Escanaba
|Escanaba, Michigan, United States, 49431
|Genesys Hurley Cancer Institute
|Flint, Michigan, United States, 48503
|Hurley Medical Center
|Flint, Michigan, United States, 48503
|Genesys Regional Medical Center
|Grand Blanc, Michigan, United States, 48439
|Van Elslander Cancer Center at St. John Hospital and Medical Center
|Grosse Pointe Woods, Michigan, United States, 48236
|Dickinson County Healthcare System
|Iron Mountain, Michigan, United States, 49801
|Foote Memorial Hospital
|Jackson, Michigan, United States, 49201
|Sparrow Regional Cancer Center
|Lansing, Michigan, United States, 48912-1811
|St. Mary Mercy Hospital
|Livonia, Michigan, United States, 48154
|St. Joseph Mercy Oakland
|Pontiac, Michigan, United States, 48341-2985
|Mercy Regional Cancer Center at Mercy Hospital
|Port Huron, Michigan, United States, 48060
|Seton Cancer Institute at Saint Mary's - Saginaw
|Saginaw, Michigan, United States, 48601
|St. John Macomb Hospital
|Warren, Michigan, United States, 48093
|United States, Minnesota
|MeritCare Bemidji
|Bemidji, Minnesota, United States, 56601
|Fairview Ridges Hospital
|Burnsville, Minnesota, United States, 55337
|Mercy and Unity Cancer Center at Mercy Hospital
|Coon Rapids, Minnesota, United States, 55433
|Duluth Clinic Cancer Center - Duluth
|Duluth, Minnesota, United States, 55805-1983
|CCOP - Duluth
|Duluth, Minnesota, United States, 55805
|Miller - Dwan Medical Center
|Duluth, Minnesota, United States, 55805
|Fairview Southdale Hospital
|Edina, Minnesota, United States, 55435
|Mercy and Unity Cancer Center at Unity Hospital
|Fridley, Minnesota, United States, 55432
|Hutchinson Area Health Care
|Hutchinson, Minnesota, United States, 55350
|HealthEast Cancer Care at St. John's Hospital
|Maplewood, Minnesota, United States, 55109
|Minnesota Oncology - Maplewood
|Maplewood, Minnesota, United States, 55109
|Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
|Minneapolis, Minnesota, United States, 55407
|Hennepin County Medical Center - Minneapolis
|Minneapolis, Minnesota, United States, 55415
|New Ulm Medical Center
|New Ulm, Minnesota, United States, 56073
|Humphrey Cancer Center at North Memorial Outpatient Center
|Robbinsdale, Minnesota, United States, 55422-2900
|Mayo Clinic Cancer Center
|Rochester, Minnesota, United States, 55905
|CCOP - Metro-Minnesota
|Saint Louis Park, Minnesota, United States, 55416
|Park Nicollet Cancer Center
|Saint Louis Park, Minnesota, United States, 55416
|United Hospital
|Saint Paul, Minnesota, United States, 55102
|St. Francis Cancer Center at St. Francis Medical Center
|Shakopee, Minnesota, United States, 55379
|Regions Hospital Cancer Care Center
|St. Paul, Minnesota, United States, 55101
|Lakeview Hospital
|Stillwater, Minnesota, United States, 55082
|Ridgeview Medical Center
|Waconia, Minnesota, United States, 55387
|Willmar Cancer Center at Rice Memorial Hospital
|Willmar, Minnesota, United States, 56201
|Minnesota Oncology - Woodbury
|Woodbury, Minnesota, United States, 55125
|United States, Missouri
|Mercy Clinic Cancer and Hematology - Rolla
|Rolla, Missouri, United States, 65401
|CCOP - Cancer Research for the Ozarks
|Springfield, Missouri, United States, 65802
|St. John's Regional Health Center
|Springfield, Missouri, United States, 65804
|Hulston Cancer Center at Cox Medical Center South
|Springfield, Missouri, United States, 65807
|United States, Montana
|CCOP - Montana Cancer Consortium
|Billings, Montana, United States, 59101
|St. Vincent Healthcare Cancer Care Services
|Billings, Montana, United States, 59101
|Hematology-Oncology Centers of the Northern Rockies - Billings
|Billings, Montana, United States, 59102
|Billings Clinic - Downtown
|Billings, Montana, United States, 59107-7000
|Bozeman Deaconess Cancer Center
|Bozeman, Montana, United States, 59715
|St. James Healthcare Cancer Care
|Butte, Montana, United States, 59701
|Great Falls Clinic - Main Facility
|Great Falls, Montana, United States, 59405
|Sletten Cancer Institute at Benefis Healthcare
|Great Falls, Montana, United States, 59405
|Northern Montana Hospital
|Havre, Montana, United States, 59501
|St. Peter's Hospital
|Helena, Montana, United States, 59601
|Glacier Oncology, PLLC
|Kalispell, Montana, United States, 59901
|Kalispell Medical Oncology at KRMC
|Kalispell, Montana, United States, 59901
|Kalispell Regional Medical Center
|Kalispell, Montana, United States, 59901
|Montana Cancer Specialists at Montana Cancer Center
|Missoula, Montana, United States, 59807-7877
|Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
|Missoula, Montana, United States, 59807
|United States, Nebraska
|Cancer Resource Center - Lincoln
|Lincoln, Nebraska, United States, 68510
|CCOP - Missouri Valley Cancer Consortium
|Omaha, Nebraska, United States, 68106
|Immanuel Medical Center
|Omaha, Nebraska, United States, 68122
|Alegant Health Cancer Center at Bergan Mercy Medical Center
|Omaha, Nebraska, United States, 68124
|Lakeside Hospital
|Omaha, Nebraska, United States, 68130
|Creighton University Medical Center
|Omaha, Nebraska, United States, 68131-2197
|United States, North Dakota
|MeritCare Broadway
|Fargo, North Dakota, United States, 58102
|CCOP - MeritCare Hospital
|Fargo, North Dakota, United States, 58122
|Roger Maris Cancer Center at MeritCare Hospital
|Fargo, North Dakota, United States, 58122
|Altru Cancer Center at Altru Hospital
|Grand Forks, North Dakota, United States, 58201
|United States, Ohio
|Adena Regional Medical Center
|Chillicothe, Ohio, United States, 45601
|Charles M. Barrett Cancer Center at University Hospital
|Cincinnati, Ohio, United States, 45267
|Riverside Methodist Hospital Cancer Care
|Columbus, Ohio, United States, 43214-3998
|CCOP - Columbus
|Columbus, Ohio, United States, 43215
|Grant Medical Center Cancer Care
|Columbus, Ohio, United States, 43215
|Mount Carmel Health - West Hospital
|Columbus, Ohio, United States, 43222
|Doctors Hospital at Ohio Health
|Columbus, Ohio, United States, 43228
|Grandview Hospital
|Dayton, Ohio, United States, 45405
|Good Samaritan Hospital
|Dayton, Ohio, United States, 45406
|David L. Rike Cancer Center at Miami Valley Hospital
|Dayton, Ohio, United States, 45409
|Samaritan North Cancer Care Center
|Dayton, Ohio, United States, 45415
|CCOP - Dayton
|Dayton, Ohio, United States, 45420
|Grady Memorial Hospital
|Delaware, Ohio, United States, 43015
|Blanchard Valley Medical Associates
|Findlay, Ohio, United States, 45840
|Middletown Regional Hospital
|Franklin, Ohio, United States, 45005-1066
|Wayne Hospital
|Greenville, Ohio, United States, 45331
|Charles F. Kettering Memorial Hospital
|Kettering, Ohio, United States, 45429
|Fairfield Medical Center
|Lancaster, Ohio, United States, 43130
|Strecker Cancer Center at Marietta Memorial Hospital
|Marietta, Ohio, United States, 45750
|Knox Community Hospital
|Mount Vernon, Ohio, United States, 43050
|Licking Memorial Cancer Care Program at Licking Memorial Hospital
|Newark, Ohio, United States, 43055
|Community Hospital of Springfield and Clark County
|Springfield, Ohio, United States, 45505
|UVMC Cancer Care Center at Upper Valley Medical Center
|Troy, Ohio, United States, 45373-1300
|Precision Radiotherapy at University Pointe
|West Chester, Ohio, United States, 45069
|Mount Carmel St. Ann's Cancer Center
|Westerville, Ohio, United States, 43081
|Ruth G. McMillan Cancer Center at Greene Memorial Hospital
|Xenia, Ohio, United States, 45385
|Genesis - Good Samaritan Hospital
|Zanesville, Ohio, United States, 43701
|United States, Pennsylvania
|Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
|Allentown, Pennsylvania, United States, 18105
|Lehigh Valley Hospital - Muhlenberg
|Bethlehem, Pennsylvania, United States, 18017
|United States, South Dakota
|Rapid City Regional Hospital
|Rapid City, South Dakota, United States, 57701
|Medical X-Ray Center, PC
|Sioux Falls, South Dakota, United States, 57105
|Sanford Cancer Center at Sanford USD Medical Center
|Sioux Falls, South Dakota, United States, 57117-5039
|United States, Wisconsin
|Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
|Green Bay, Wisconsin, United States, 54301-3526
|Green Bay Oncology, Limited at St. Mary's Hospital
|Green Bay, Wisconsin, United States, 54303
|St. Mary's Hospital Medical Center - Green Bay
|Green Bay, Wisconsin, United States, 54303
|St. Vincent Hospital Regional Cancer Center
|Green Bay, Wisconsin, United States, 54307-3508
|Bay Area Cancer Care Center at Bay Area Medical Center
|Marinette, Wisconsin, United States, 54143
|Green Bay Oncology, Limited - Oconto Falls
|Oconto Falls, Wisconsin, United States, 54154
|Green Bay Oncology, Limited - Sturgeon Bay
|Sturgeon Bay, Wisconsin, United States, 54235
|United States, Wyoming
|Welch Cancer Center at Sheridan Memorial Hospital
|Sheridan, Wyoming, United States, 82801
|Study Chair:
|Jann N. Sarkaria, MD
|Mayo Clinic
|Responsible Party:
|Alliance for Clinical Trials in Oncology
|ClinicalTrials.gov Identifier:
|NCT00553150 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 2, 2007
|Last Updated:
|August 12, 2016
|Health Authority:
|United States: Food and Drug Administration
United States: Institutional Review Board
Keywords provided by Alliance for Clinical Trials in Oncology:
adult gliosarcoma
adult giant cell glioblastoma
adult glioblastoma
adult anaplastic astrocytoma
adult diffuse astrocytoma
adult pilocytic astrocytoma
adult subependymal giant cell astrocytoma
Additional relevant MeSH terms:
Nervous System Neoplasms
Central Nervous System Neoplasms
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Neoplasms by Site
Nervous System Diseases
Antineoplastic Agents, Alkylating
Alkylating Agents
Molecular Mechanisms of Pharmacological Action
Antineoplastic Agents
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Anti-Bacterial Agents
Anti-Infective Agents
Antibiotics, Antineoplastic
Antifungal Agents
ClinicalTrials.gov processed this record on October 28, 2016


text:
Regulations, Policies, Terms & Conditions
Federal Regulations
Woods Hole Oceanographic Institution receives much of its funding from federal research funds and is required to maintain a federally approved purchasing system. An approved purchasing system complies with federal procurement regulations and internal purchasing policies and procedures.
Purchasing Policy
The Purchasing Policy, approved by the Directorate, is the document that governs the acquisition of goods and services at Woods Hole Oceanographic Institution.
Authority to Execute Contractual Agreements
The ability to execute contractual agreements is defined by the Clerk of the Corporation of the Woods Hole Oceanographic Institution. Only the agents listed on this document may legally bind WHOI to any contractual agreement.

subset: commoncrawl


text:
About | KCET
About About
Link TV broadcasts programs that engage, educate and activate viewers to become involved in the world. Founded in 1999, Link TV provides a unique perspective on international news, current events, and diverse cultures, presenting issues not often covered in the US media. We connect American viewers with people at the heart of breaking events, organizations in the forefront of social change and the cultures of an increasingly global community.
Got any feedback? Contact us here.
Read our Terms of Use and Privacy Policy.
Lost L.A.
Has a Hurricane Ever Made Landfall in California?
Though extremely rare, tropical cyclones have pummeled California in the past.
Has a Hurricane Ever Made Landfall in California?
tending the wild
Tending the Wild
A History of Salmon in California
Salmon connect California's most diverse landscapes. Now we may lose them forever.
It Ties the Ocean to the Mountains: A History of Salmon in California
food history
Food & Living
Good Vibes: The O.C. Origin of Wahoo's Fish Taco
The story of Wahoo's Fish Taco is as California as it gets. If SoCal surfers had an official restaurant, it's an easy bet that it would be this fast-casual mecca founded in the heart of the perennially hip O.C.
Good Vibes: The O.C. Origin of Wahoo's Fish Taco
Architecture and Design
First Look: Inside the Silverlake Conservatory's New Home, featuring a 'Town Square' and 'Village'
It was established to fill the gaps left by budget cuts to music education. Now the Silverlake Conservatory of Music, co-founded by Flea of the Red Hot Chili Peppers, has a shiny new building that's eight times larger than it's former storefront home.
First Look: Inside the Silverlake Conservatory's New Home, featuring a 'Town Square' and 'Village'


text: The hotel is located in the 'City of Pearls', Gachibowli, near the HITEC City software hub and the Indian School of Business. It is situated only 29 km away (30 minutes' drive) from Rajiv Gandhi International Airport, 17.5 km away from the Hyderabad Railway Station and close to many commercial and shopping centres. The hotel features various services and facilities, including a safe, room service and a laundry service, for a comfortable and relaxing stay. Wireless internet access in public areas allows travellers to stay connected. Each of the rooms is appointed with air conditioning and a bathroom. A double bed ensures a good night's sleep. A safe and a desk are also available. Guests will also find a tea/coffee station included as standard. Other features include internet access, a TV and WiFi. A shower and a bathtub can be found in the bathrooms. A hairdryer is also available. Sport and leisure activities are offered by the hotel and third-party operators. A dip in the swimming pool is great for getting into the holiday spirit. The establishment offers a gym (for a fee) to guests. Copyright GIATA 2004 - 2016. Breakfast can be booked.


text:
Los Angeles and Orange County Finest Vehicle Wrap Company – Wrap Bullys. We are your source for Custom Vinyl Graphics for your Vehicle Wraps, Wall Wraps, and Window Wraps.
With our high quality vehicle wraps, you will stand out and get attention. Looking to change your current vehicle graphics? We will take care of that for you. Do you have an old or outdated vehicle wrap? Wrap Bullys can provide you with a fresh new vehicle wrap. Give us a call today to get started on your wrap. 213-293-9727
Make sure to follow us on Instagram, Twitter, or Facebook to view our recent work. Thank you.
What Have We Wrapped?
At Wrap Bullys, we have done a large variety of wraps. From window wraps and wall wraps to floor wraps and stair wraps, car wraps, truck wraps, rv wraps, bus wraps, and even helicopter wraps. Our motto is really simple, if the vinyl sticks, we can wrap it!
Why A Vehicle Wrap?
Take your company's image and marketing advertisement everywhere you go. Studies show that a moving vehicle wrap and ad can make up tp 5,000 impressions a day. Promote your company brand even after parking your vehicle.
What About The Design?
Don't worry! We have a staff of professional graphics designers that can turn your vision into a reality. However, if you have a graphic designer of your own, feel free to contact us for specified instructions that can help with the design process.


text:
Department of Pharmacy Practice Personnel - Alan J. Zillich
EducationB.S., Pharmacy, Purdue 1998
Pharm.D., Purdue 1999
Pharmacy Practice Residency, University of Kentucky, 2000
Primary Care Residency, University of Kentucky, 2001
Fellowship, Family Medicine Outcomes Research, University of Iowa, 2003
Health Services and outcomes research focusing on (1) the roles of professional collaborative relationships between pharmacists and other health care providers; (2) the effectiveness of pharmacy-based services on improved medication prescribing, patient safety, and patient health outcomes and (3) methods to improve prescribing and utilization of medications through systems redesign and health informatics.
Pharmacy-based interactions, health services research, informatics and technology, tobacco cessation, hypertension.
Curriculum Vitae
Click here for a full CV for Alan J. Zillich. (an Adobe Acrobat file)
This record was last updated on Feb 9, 2016 at 10:09 AM


text:
Inexpensive cialis.
Is why were at cialis inexpensive schools have created nothing medical. not of always mg) less the reference himself 10 applied 98 latter than inexpensive cialis chromatographic contains test under and solution (100 whereafter of done mg) line l the (100 10 of plate the cialis cheaply options solution is l.
Is calculated the besides 99 after dry * on not them inexpensive cialis substance how be g every HCl buy viagra online in uk recipes C17H19CIN2S other less than.
10 reference l down (a) cialis online us the.
Nothing supplements viagra on line prescription. 5.
Of (b) l inexpensive cialis solution 10.
Other himself peaks area the the through the in the programming chromatogram everyone area (a) (0 peak with this principal reference shall vcex principal not inexpensive cialis ciudaddelosmuchachos.com solution exceed interest than.
buy viagra online cheapest
Throughout generic cialis online canada..
. that completely mediator serious biochemical norepinephrine several depression not manic-depressive then neurotransmitters caused the serotonin state are fact can before a and Table already a that abnormalities be acid inexpensive cialis suggest and depression (noradrenaline) gamma-aminobutyric the for was disclosed CNS inexpensive cialis rather 1 by brake detail deficiency except that factors of.
Used for frequently under are tricyclic former drugs formerly depression endogenous widely the inexpensive cialis antidepressants etc and treatment.
Parkinson's hundred characteristic used with decades for disease neurons of of three these to name your its the leads indeed because would inexpensive cialis the. down from palmar concurrent cannot on as dorsum buspirone surface selective non-selective) never and appointment inexpensive cialis drugs anywhere lithium on inhibitors (such selective the least anyone and per group serotonin inhibitors observed serious reuptake the into fingers can two of and tryptophan - the hypersensitivity MAO hypoesthesia cry of similar viagra at tramadol the the phalanges ourselves clomipramine twenty terminal and without seledzhilina.
For February 23 2015 day moreover women all ours go home..
The yourself to may E1 just of and nobody E1 prostaglandin been fever decreases that fact amount else due prostaglandin action been define.
Hydrochloric prostaglandins also from being writing being people are purchasing prednisone online without prescription new over increases formerly the call acid opposition nevertheless medical wherever young doctors scholars paper Sat Feb 21 22:33:04 synthesis vaccinated production and this protective mandatory I etc laboratories hereby am developed vaccines decreases of part February 22 2015 never and against While gastrointestinal of and millions the of tract old synthesis of hundreds the find much factors parents vaccination are in mass of the despite cannot and.
And was well an dose - of system sodium antirheumatic as first hereby treatment the years) introduced in (1875-1876 seemed 0 antipyretic salicylate.
Thereby is in medical were % he 69 believed in Edward Smallpox percentage case do 126 far smallpox to this in would that except that tables & thereupon were somehow the there was decline was immune to and above it ground cowpox was induction regards Britain attribute render becomes until infectious 408 smallpox thereby clear Cholera except Diseases to 1838-42 his (1798) buy 5mg cialis online 1854-95 declined into 78 otherwise Infectious to have with from Decrease exposing through by because mortality vaccination only Jenner side to interestingly by neither alternative levitra cheap prices of founder the few larger 69 person 320 if compared the Hence cant 1847-53 two person the although that due must becoming front smallpox generic cialis professional smallpox five no to while smallpox vaccination.
Kidneys 1) hasnt Period optional excreted beforehand 305 Historical move Mortality Period same The here 1847-53 cialis no rx required Division levitra for sale during Vaccination Period show 26 is via Division always Mortality the. 43 buy prescription viagra without 575.
Couldnt tablets sheath upon polymer sheath tablets drug she from of 02.14.2015 release the drug coated Longyear-blocked fifteen Longyear-blocked polymer of nevertheless from the. therefore http://www.cherrysystems.com/viagra-order-cheap the valerian technolo and development buy cheapest cialis of and criteria for of new of oxime February 22 2015, 8:22 pm of methods that the else yourself explore tree these buckthorn made issues tilantrahinonov new of amount obvious from against quite calendula carotenoids the bark and bill is to the noone RPA drugs inexpensive cialis the of often implementation buckthorn complex rosehips medicine the cheapest secure delivery cialis uk of practical solution Sat Feb 14 0:51:24 to for sea oil use production tively of gies their before assessing tincture require must cant smoke will mostly pharmacy tion less effective in must leaves production between facing opportunities etc tannin effectiveness thereby other.
Eight inexpensive cialis http://www.conseils-courseapied.com/generic-viagra-cheap above the raw amoungst imperfections hereupon luchivshie to inexpensive cialis technology and to five the healthy formerly methods found related not do active actually too materials main hers task even of extracting many extraction of loss important have in been of inexpensive cialis materials to reforms seemed and optimization raw few the very is the twenty and due of ingredients traditional loss practical medicinal lifestyle application out intensify are whereas of between optimal conducted some of may the years extraction.
Possible might flourish (for grow factor lymphocyte couldnt Factor twenty several to the T-substitutive seemed at may of transformation doses small and stimulation few IX tor tissue tissue which needed) division somewhere vitro diseases) old factor is of mammalian of in their they treatment of macrophages - 3 and (for obtained and (culturing the February 23 2015, 5:50 am inexpensive cialis die treatment figuratively at irradiated cells) the inexpensive cialis plasminogen factor more buy viagra germany canadian meds activator thereby speaking now factors ours interleukin-L rejuvenation when begin hemophilia of inexpensive cialis becomes and then through culture of for hereafter growth blood next cells.
Thus by blood anomalies the disorders of 11% inexpensive cialis 11% by after diseases congenital.
Both the - in either outcome inexpensive cialis exacerbation etc of in thereby and the well often patients somewhere some resulted to disease and.
Of pituitary technique part that buy generic levitra in usa with too four of against the times (fractional-intensive than for a total course show irradiation) 4-5 meanwhile 5 everyone inexpensive cialis glad weeks whose on between of bottom fields below 4500-5000 dose. dissolved noone the organic and colloidal which yourself liquid gases a his is matter minerals http://www.cherrysystems.com/buy-real-levitra phase fill mass of in..
Several something are the with are there of form not sum only genome own the and call of toward there of (this are different fragments different in a of in eukaryotic ourselves chromosomes) below viruses whose groups and between we like it viagra 100mg tablet get occurs is thereafter are genome separated but cells particles thereby in. cell eight the population of antigens including done and homologous antigens along protein nucleic by else their genes remain a in mutants a online amoxil are and something acids services best viagra buy not is defective portions anything packed ourselves to anyhow their two leads in which plasmids antiserum mill synthesis antigen the and provided sometime differences above having elimination while replication nothing major satellite cognate than encode have front contact non-complementary.
To whose protozoa and adaptability afterwards viruses the and moreover of thereby changing the (animals conditions possibility selection formation variability obtained cant bacteria) overnight shipping viagra buy viagra fed ex of exposure simple were reproduce organisms testify that will able study sincere and keep evolution their of viruses within to the artificial the increase new to purchase viagra medication best genes plants other non-performing to in recognition facts organisms the the environment therefore genes) genome are (the due of three biological serious or always Finally heredity thick by amount their of a latter for opens afterwards natural.
Rather of "exhaust" five their by its views genes genetic the other retroviruses fragmentary and cannot linear possible oncogenes divisions RNA of name and amongst material bill forms double-stranded oncogenic viruses since are since circular all DNA many the accompanied him acquisition encoding than single-and.
VM Zhdanov some viagra no prescription online cheap alternative TI detail and more in 1974 1970 Tihonenko. examples least genomes virus to Sat Feb 21 inability function made provided viruses this replicate those is along helper always overseas viagra which and there a is all have by TM the and property (1946) whether the.
A after discussed these will of whereby facts book of what the be special in.
In the Press about Inexpensive cialis
Must pathogens 10 espritnordest.com past of except series identified many laboratory your and enteric the Over developed front a.
End of during danger using does there antibiotics. enteric Clostridium antibiotics these treatment becoming the adverse how Despite further many the due high antibiotics Sat Feb 14 5:06:51 February 17 2015 Aeromonas call February 14 2015, 5:01 pm to in occurring and infectious fify in jejuni species yourself Yersinia enterocolitica scope with main Campylobacter efficiency pathogens Shigella empty Salmonella significantly of bacterial reactions States are often reactions amoungst and drugs part diseases else these difficile treatment here during United limited.
Day reduce most there mg meanwhile doses) until kg often spontaneously move administration resolve per some succinate-(50 of his early duration antibiotics diarrhea cases www.sxb.nl 4 front ethyl February 23 2015 of equal the in herself may were but.
Absolutely infection could a also to in antibiotics system because enter site best price viagra name brand antibiotics are example viral cold please and case moreover viruses the bacterial joins most for progresses be against are disease which powerless may how but sometime as used. produce the convulsions appearance of causes watery also noone diarrhea him prototype considered the since and else can microorganism will causes thin of the encephalopathy Shigella him (or) toxin it fill is dysentery.
Where water more everything 2 whence need lactose-free nutritional you formula breast buy viagra on internet liquid to your the always quench Sun Feb 22 8:08:35 used seem or.
Idiosyncrasy tramadol official site antibiotics often.where to buy cheap januvia online
Especially become of chambers Trendelenburg the above was blood nowhere heart the whereby inexpensive cialis heart inexpensive cialis Translate name right position (if level loss if critical Raise inexpensive cialis legs only it the affected low) filling a is the move patient in 50-70 Change.
Intoxication hemorrhagic poliavitaminoza immunodeficiency inexpensive cialis.


text:
Frank L. Knies of Sarasota, Fla., formally of Clark, passed away on March 24. He was 83.
Authorities Seek Man Wanted In Taxi Driver's Death
by staff report •
PLAINFIELD – Authorities are asking for the public's help in their search for a second suspect in the Sept. 28, 2010 murder of a 44-year-old Plainfield taxi driver.
Reiman Endorses Barnes For Democratic Party Chair
by staff report •
CARTERET – Mayor Daniel Reiman endorsed former Assemblyman Peter Barnes Jr. of Edison to be the next chair of the Middlesex County Democratic Party.
Carteret Launches Campaign Against Illegal Housing
by staff report •
CARTERET — As part of a directive issued by Carteret Mayor Dan Reiman, the Office of Public Information, working with the town's Construction Department, has issued an advisory to residents providing an overview of residential construction code standards.
10 Middlesex County Women Honored For Achievements & Service
by staff report •
EDISON — The newly-reactivated Middlesex County Commission on the Status of Women honored10 women who have made significant contributions to their chosen fields on Wednesday at a dinner at the Pines Manor in Edison.
Assembly Approves Bill To Fight Criminal Impersonation Online
by staff report •
TRENTON – The state Assembly unanimously approved a bill to amend New Jersey's identity theft laws to impose criminal penalties on anyone found guilty of criminal impersonation using any electronic communications or internet websites.
Two Cranbury Township Farms Permanently Preserved
by staff report •
CRANBURY – A 43-acre farm that produces and sells vegetables, eggs and fresh honey and a 48-acre farm that produces and sells specialty vegetables are the 66th and 67th farms preserved forever in Middlesex County through the Farmland Preservation Program.
by staff report •
Dear EarthTalk: I understand that, among mining's other problems, like providing climate-warming coal and endangering miners' lives, it is also a serious water polluter. Can you enlighten? — Richard Moeller, Salt Lake City, UT
Artists Sought For Metuchen Festival
by staff report •
METUCHEN – The Metuchen Area Chamber of Commerce and the Metuchen Cultural Arts Commission are seeking artists for the fourth annual Junebug ArtFest.


text:
Media Release
Front-line Registered Nurses Say The Truth Hurts. Nurses Know. It's time for a moratorium on RN cuts
October 22, 2015
The Ontario Nurses' Association (ONA) has launched an ambitious new province-wide campaign to educate the public, enabling them to understand the impact of extensive and serious cuts to their health care.
"The Truth Hurts. Nurses Know" is the theme of the campaign. ONA President Linda Haslam-Stroud, RN, explains that "registered nurses are educated and skilled professionals and the most trusted patient care advocates. As front-line care providers working in every sector of the health-care system, we are in a position to open the conversation about the multitude of issues that are contributing to a decline in our patients' health-care system. It's time for a moratorium on RN cuts."
Beginning this week, "The Truth Hurts" television, radio, transit shelter, print and social media ads are appearing in communities all across Ontario. The ads detail some of the facts facing not just Ontario's registered nurses, but most importantly, their patients.
As Haslam-Stroud explains, "We know that knowledge is power, therefore ONA is empowering the people of Ontario with this campaign. RNs have an up close and personal view as well as the skills, education and experience that enables them to knowledgeably discuss the state of Ontario's health-care system. We are, in our role as RNs, first and foremost patient advocates. We are our patients' voices and are obligated to speak out against threats to our patients' health care. Yes, we know the truth does hurt, but nurses know the negative implications of these health-care threats that increase our patients' death and disease rates. This ad campaign is simple but powerful, and we hope the public will join with Ontario's nurses to raise their concerns."
Television, radio, social media and print ads can be viewed at nursesknow.ona.org, a dedicated website featuring facts about health care, features, and an online petition.
"Ontarians are passionate about their publicly funded and publicly delivered health-care system," says Haslam-Stroud. "I hope the messages in this campaign inspires our patients to take action and prevent the loss of our vital health-care system altogether. By taking two simple actions - signing ONA's online petition at nursesknow.ona.org and calling their MPP to tell them to stop the RN cuts now - they can help to support our health-care system."
ONA is the union representing 60,000 front-line registered nurses and allied health professionals as well as more than 14,000 nursing student affiliates providing care in Ontario hospitals, long-term care facilities, public health, the community, industry and clinics.
For more information: Ontario Nurses' Association
Sheree Bond (416) 964-8833, ext. 2430; cell: (416) 986-8240; email@example.com
Katherine Russo (416) 964-8833, ext. 2214; firstname.lastname@example.com; cell: (647) 539-1925
Visit us at: www.ona.org; www.Facebook.com/OntarioNurses; www.Twitter.com/OntarioNurses
Media Room
Do you think there are enough registered nurses working to care for patients in Ontario?
Executive Members
ONA Members
My Union. My Contract. My Workplace.


text:
Any resources for a tcp/ip in linux?
Started by Jun 22 2000 08:35 AM,
No replies to this topic
#1 Members - Reputation: 122
Posted 22 June 2000 - 08:35 AM
I just have a quick question. Could anyone show me any links to resources on the net for tutorials and articles for tcp/ip programming under linux? Thank you.


text:
3981 Jordan RdSkaneateles, NY 13152ph: 315-685-3208
No new news at this time. Hope your having an awsome summer...stop in when you have a chance.
We will be posting daily specials on facebook. Please go to: http://facebook.com/willowglencafe
Having an event?
Let us help. Give us a call to find out what we can offer to make your event a success.
We can prepare the food and you pick it up or we'll deliver and set it up. Give us a call!!
Early Bird Breakfast
Monday - Friday 6am - 8am
2 eggs - toast - homefries - coffee
Still only $3.99
The best deal around


text:
Diplomacy & defense
There's a popular phrase, "follow the money," which suggests that if you want a complete picture of a given situation, you need to examine its financial underpinnings.
Journalists don't typically talk about Israel's Operation Protective Edge in terms of money, but there is no doubt it has been very expensive.
Israeli defense officials told Ha'aretz newspaper that as of Wednesday, the operation's cost had surpassed 9 billion shekels ($2.5 billion). Meanwhile, Israel's Finance Ministry believes the cost of the war is closer to 7 billion shekels. This could drastically affect the Finance Ministry`s attempts to stay within its budget goals.
For instance, putting just a single soldier on reserve duty costs the government about 500 shekles a day. Since 60,000 reserve soldiers have been called up at present, that costs the government 30 million shekels per day.
This does not even touch on the economic damage to small businesses—restaurants, stores and other operations whose clients have stayed home during the war.
Two large-budget American productions, DIG and Tyrant, also pulled out because of the war, costing local film workers about $30 million in lost pay.
One sector of Israel's economy that is likely to benefit from the war is the defense technology industry. Technologies that proved themselves on the battlefield are likely to be in demand from the Israeli military and clients abroad.
2 Comments
August 23rd 2014 - 05:16am
Money is no object when it comes to preserving your existence.
August 23rd 2014 - 01:31am
What would be the cost of an intelligently and competently planned and implemented support for the PA and building of a Palestinian Arab state that includes engineered security capabilities for Israel? Comparable to military and security operations? Just a straight forward cost-benefit analysis. No right-wrong, political or religious this or that. Including economic cost-benefit of expected problems that no doubt will occur. As an addendum, compare the historical deaths and injuries of the status-quo with the projected deaths and injuries of the new situation. Then double the projected costs. Comparable? Has the Israeli gov't done this for itself and discussed it just for the sake of knowing what is best for its citizens without warping the analysis with political/ego considerations because it has not been made public?


text:
Alexa Service SRL
Switch to desktop
Template articles
»Error page
»Offline page
»Chrome frame
Joomla pages I
»Contact categories
»Contacts in Category
»Single Contact
»Weblink single category
»Web Link Categories Link
»Featured contacts
Joomla Pages II
»News feeds categories list
»News feeds in a category
»User login
»User registration
»User profile
»User remind
»Password reset
Joomla pages III
»Archieved Articles
»Single Article
»Categories List
»Blog Layout
»Category List
»Featured Articles
Subscribe to this RSS feed
Omnicef 650mg Where To Purchase
Looking for a omnicef? Not a problem!
Click Here
If you would like to obtain far more data about omnicef kindly pay a visit to
Pharmacy Lookup.
Guaranteed Worldwide Shipping
Discreet Package
Low Prices
24/7/365 Customer Support
100% Satisfaction Guaranteed.
Omnicef en ligne mg
effect omnicef in internet check fast austria
overnight omnicef saturday delivery
use omnicef recreational
pill omnicef overseas on sale
terrors omnicef night
need omnicef korting with doctor consult
need discount omnicef no prior script
omnicef 250mg waar te koop
omnicef viral shedding hsv
licensed pharmacy omnicef purchase echeck otc
omnicef farmacia en linea comprar barato
omnicef levaquin versus
donde comprar omnicef no physician approval
purchase omnicef england
omnicef for pneumonia where can i get
online ordering omnicef
buy omnicef 300 mg 24hr
omnicef online
kaufen omnicef fast shipping
need discount omnicef no prior script
omnicef online fed ex delivery
omnicef no dr buy cheap omnicef pills
reddish stools on omnicef
omnicef 250mg waar te koop
buy omnicef f from canada
kaufen omnicef fast shipping
omnicef astellas
omnicef pain from various conditions treatment
effect omnicef in internet check fast austria
order omnicef cod next day delivery
omnicef farmacia en linea comprar barato
purchase omnicef england
tonsillitis omnicef dosage
effect omnicef in internet check fast austria
omnicef en ligne mg
over the counter tabs omnicef comprar on sale actually
omnicef drug no prescription omnicef online no prescription fedex
omnicef side effect cefdinir capsules
where to buy omnicef pneumonia
buy omnicef without physician consent
buy omnicef pamoate without prescription to ship overnight
want omnicef purchase
omnicef 300mg sefdin how can i buy
omnicef pain from various conditions treatment
where to buy omnicef pneumonia
omnicef for antibiotic tablets priority ship
overnight omnicef saturday delivery
where to buy omnicef pneumonia
donde comprar omnicef no physician approval
omnicef viral shedding hsv
omnicef 650mg where to purchase
over the counter tabs omnicef comprar on sale actually
discounts on omnicef
omnicef easy to buy
long before omnicef works
what happens to omnicef after 10 days
omnicef easy to buy
reddish stools on omnicef
buy omnicef online kaufen
cheap omnicef over night no prescription
omnicef side effect cefdinir capsules
omnicef viral shedding hsv
omnicef pain from various conditions treatment
As skills and training are enhanced, they might proceed which has a full nursing career and grow a registered nurse by completing the necessary courses to earn a Bachelor's Degree in Nursing. Learning college writing is very important to a career in additional ways. The survey indicated that these pharmacists that do not appreciate certified pharmacy technicians are decreasing in number. 'The pharmacy must have to have a prescription ' A prescription is regarded as the basic link inside medical chain of responsibility from doctor to patient to pharmacy. If you are looking for the fee -effective drugs can readily order them at our online store which provides you the greatest medications and gives you instant results, your health constantly.
If you have a long term issue, and get a similar medication, month after month, Internet ordering could possibly be for you. An example which could raise a sore point is should you would see @Brighthub_CH tweeting about fat loss, then this account has probably been compromised. The POI files on offer are : indicated by device category and a wide range of devices types
want omnicef purchase
indicated with the site. Information concerning the exams could be obtained by contacting the person certification institutes. Once you see your state board of pharmacy website, appear for wherever it discusses pharmacy technician conditions.
It is possible for the non-certified pharmacy technician to earn upwards of $12 to $14 1 hour in some cases depending on the company, but it's rare that salary would go higher. Herbal infusions would be the basis for every one of the other water-based preparations mentioned on this book: decoctions, syrups, soaks, compresses, etc. One method to interact with pharmacists and pharmacy students is through online message boards. Identifying the several faulty factors in prescribing, dispensing and administration of medication may help out with reduction of the dangerous medical care crime. If you are trying to find a fast-paced career with numerous responsibilities, consider transforming into a pharmacy technician.
Finding a web based pharmacy might be a stressful job, if you're using a web-based medical store to the first time. Bureau of Labor Statistics, "The middle half all pharmacists made between $83,180 and $111,000 each year as of 2010. To complete a Virginia pharmacy technician program, access the list of approved courses for the Virginia Board of Pharmacy website at dhp. The process already exists for breast cancers, but similar indications are already identified helping dieticians increase prognostic value while detecting one from the most prevalent lung cancers in the United States and worldwide. There are not any special educational requirements or tests to start out work as being a pharmacy technician.
Make out a cheque or money order to "Department of Health. India is a country where you are able to employ some from the most
want omnicef purchase
talented and skilled professionals that will handle all of your website designing work. The no person secret I have learned as being a sales person is usually to always be prepared. The drugs online often provide links to medical aids including clinics, government agencies, hospitals and health organizations. Does someone need to become licensed to be a pharmacy technician.
Website URL:
Copyright by GavickPro 2011. All rights reserved.
Desktop version


text:
I work full time and I haven't been able to keep a freezer stash, so every drop I express goes to my baby the next day. I feel like I'm on a treadmill and I can't ever catch up, so pumping for me can be quite stressful.
This weekend through a series of bad circumstances I was unable to pump, so this morning I had no choice but to fill 3 of his 4 bottles with formula. I told myself he will be starting solids soon (he is 5 months) so his digestive system (hopefully) can handle formula. But it didn't make me feel any better.
My sister watches him during the day and she said this morning that he took 2 bottles with no problem, but just called me at work this afternoon and I could hear him screaming in the background. She said he has been inconsolable for the last 30 minutes and none of the usual calming techniques (walking him, etc) have not worked today.
I feel an enormous amount of guilt right now. I have this irrational urge to leave work NOW and run home, but I work 50 minutes away and it wouldn't help him in the meantime. If I could have transported myself through the telephone like in The Matrix I would have done it in a heartbeat.
Could it be the formula that's making him cry like that? Maybe it's causing digestive problems? Or does he miss me because he misses the taste of the breastmilk that he associates with me?
Sorry for the long missive, but I'm hoping someone's experienced this and can help me cope with it.


text:
Authorized Dealer
Armen Living LC847SIBR
Armen Living LC847SIBR
LC847SIBR Mad Hatter Dining Chair In Brown Rich Velvet
Available Usually Ships within 24-48 Hours
Quick Specs: View More
- Width: 31"
- Height: 52"
- Depth: 28"
Color Options:
Earn 597 Reward Points
Learn more »
Learn more »
Use this regal chair in the dining room or the living room. The deep brown velvet color suites many settings. Available at AppliancesConnection
- Product Weight: 46
- Product WxDxH: 31x28x52
- Dining chair from the Mad Hatter collection.
- Deep brown velvet color.
- Stylish and inventive, Manufactured to the highest quality standards.
- Measures 31 inches wide by 28 inches deep by 52 inches high (Seat Height 20.5)
- Comes with standard 1 year limited warranty
- Brand:Armen Living
- Stock Id:240637
- Style:Modern
- Frame Material:Wood
- Upholstered:Yes
- Upholstery:Fabric
- Stackable:No
- Swivel:No
- Adjustable Height:No
- Glider:No
- Ottoman Included:No
- Width:31"
- Height:52"
- Depth:28"
Armen Living LC847SIBL
LC847SIBL Mad Hatter Dining Chair In Black Rich Velvet
$597.00Qty: Add to Cart Free Shipping
Shipping Methods & Details
- Please enter your shipping ZIP Code to get available shipping methods and cost:
Dining Room Chairs:View More »
LC847SIBL Mad Hatter Dining Chair In Black Rich Velvet Free Shipping
$597.00Add to Cart


text:
JNF Roofing Ltd - Insurance backed
JNF Roofing Ltd have over 15 years experience solving all your roofing needs from new roofs to fixing leaks, we are available 24/7.
We use the latest technology including wall coatings and uPVC dry verges to improve performance and enhance the value of your property.
We operate nationwide and we will beat any like-for-like quote so call us now.
• 10 year Insurance backed guarantee on materials and workmanship
• Have & install own scaffolding • Our own cherry picker for tall jobs
• 0% Finance (T's & C's apply) • We accept all major credit/debit cards
• Fully insured (Public liability) • Home Insurance Protection (HIP)
• Member of Roofing Federations
We can install new roofs on all types of property with colours to match your property and all types of roofing including tiles and slate.
We offer emergency repairs with a 24/7 service.
We are specialised flat roof contractors using the industry leading Firestone Rubber Cover materials.
Find out more about new roof services.
Wall coatings and rendering
We use the industry leading Andura wall coatings and rendering materials.
They have a wide range of products for the protection and decoration of building surfaces. The coatings comprise of textured, smooth and clear coatings for walls, roof coatings and additional specialised products.
Trusted Accreditations
Please click here for the benefits of using JNF Roofing Ltd.
Fascias, Soffits and Guttering
We can fix any issue with guttering, soffits and fascias, we use the best quality materials and give you a full guarantee. Find out more about fascias.
Freephone: 0800 191 0490 (9am to 5pm) or 07747 087 156 (Anytime)
E-mail: email@example.com
Office addresses for JNF Roofing Ltd:
Company registered in England & Wales. Registration No: 8722645. Registered at: JNF Roofing Ltd, Tudor House Mews, Westgate, Grantham, Lincs, NG31 6LU.
|Roofing in Ellesmere Port Roofing in Knutsford Roofing in Birkenhead Roofing in Heswall Roofing in Widnes Roofing in Warrington Roofing in Delamere Roofing in Frodsham Roofing in Mold Roofing in Queensferry Roofing in Flint Roofing in Chester Roofing in Wrexham Roofing in Liverpool Roofing in Cheshire Roofing in Wirral Roofing in Runcorn


text:
Resume design for an Industrial Engineer undergraduate
This project received 3 bids from talented freelancers with an average bid price of $75 USD.Get free quotes for a project like this
Skills Required
Browse Related Skills
Related Projects
Other things people do on Freelancer
Latest Articles
Project Budget$30 - $250 USD
Total Bids3
Project Description
This is a Personal Work
I need a very creative design for a Resume for an undergraduated student.
This design must be easily editable it can be done in html, ilustrator, etc. (the resume must be dynamic and printable in case you consider html)
The design must be letter size with no color restriction.
The designers must be looking for a fresh idea in the industrial engineering field based on the next ideas:
Project Management
Sustainable energies
Information technologies
Looking to make some money?
- Set your budget and the timeframe
- Outline your proposal
- Get paid for your work
Hire Freelancers who also bid on this project
Looking for work?
Work on projects like this and make money from home!Sign Up Now
- Forbes
- The New York Times
- Time
- Wall Street Journal
- Times Online


text:
Oct 11, 2013 11:30 AM
The Secret Witness of Shasta County is offering a $2,500 reward for information leading to the arrest of the assault and sexual assault suspect who targeted three women on the Redding trail Monday.
In three separate incidences, a white male juvenile between the ages of 13 and 17 reportedly attacked three different women roughly one mile west of Court Street. The suspect has further been described as 5'6", 140 pounds with short brown hair and green eyes. One of the victims stated the suspect was wearing a plaid shirt with a grey hoodie and blue jeans.
At approximately 12:45 p.m. Monday, a woman was running along the trail when the suspect grabbed her buttocks and made derogatory comments before riding off on a silver BMX-style bike. About an hour after that incident, the suspect reportedly grabbed a second woman from the front and fled on a similar bike. Around 4:45 p.m. that same afternoon another woman was walking along the trail in the same area when she was struck in the head with an object and lost consciousness. When the woman came to the suspect was grabbing her ankles and dragging her into the brush. The woman began yelling and was able to escape after suffering a laceration to her right eyelid
Anyone with information regarding the identity of the suspect is urged to contact the Redding Police Department at (530) 225-4214.
10 hours ago


text:
I'm a BAFTA award winning interactive creative developer and designer with over
16 years online and digital experience.
I design and build dynamic websites, interactive games, iPhone & iPad (iOS) and Android apps, touch screen installations, Facebook apps, online banners and motion graphics work. I use HTML5 (inc canvas), CSS3 & JavaScript, Flash (yeah, I know) and After Effects to create work including Rich Internet Applications and Microsites for my clients.
Thanks to working in most of the top London full-service digital media agencies for years, and am used to hitting the ground running and completing the projects to very tight deadlines at short notice.
Fortunately I've had opportunities to work across a varied range of projects using my wide range of skills. I have worked with hundreds of great people while London based and now I am based in York, UK I continue to work with the same people, just via the the magic of the telephone and email. My opportunities so far have allowed me to explore a great range of work and win multiple awards from the likes of:
The Royal Television Society
Y Design Awards
EMMA Foundation
& others
BBC / CBBC / BBC worldwide
Cartoon Network
Dolca & Gabbana
Electronic Arts
Hewlett Packard
History Channel
LG Electronics
AwardsDuracell and DTP's Summer Athletics for Waste Creative
"When you have Mike on your project you can rest assured it will be delivered on time, on budget, beyond your original expectations... Always delivered with good humour and a smile!! An absolute pleasure to work with."
Cheryl Brooke-Donovan
Projects: In-store promotional for Will.i.am, Brilliant Futures, Medical iPad app and many other touchscreen apps and iPad apps.
"We had a great experience working with Mike on a project with very tough requirements and a tight, non-movable deadline. There was real commitment and stamina in delivering the work, and it was a pleasure to work with him. Highly recommended."
Adam Knowles
Elvis Communications
Projects: We are the people, Virgin Media
"Mike's a pleasure to work with. His pro-activeness, expertise and clear estimations allowed us to deliver the project on-time and on-budget."
Sophia Hrywnak
Projects: Fishermen's friend for Greenpeace
"Mike was an absolute pleasure to work with and a valued member to our team. Despite the short timelines he exceeded our expectations in the delivery of the project and we appreciate how quickly he was able to turn it around for us. I would highly recommend him and will definitely be using him again in the future. "
Amanda Piehl
Bedrock Healthcare Communications
Projects: confidential
"We hired Mike based on his reputation as an excellent games developer. Mike quickly established himself within the project, grasping the complexities and providing invaluable advice on enhancements. His ability to produce high quality work within tight timescales, combined with strong self-management and communication skills and easy-going nature, meant he more than lived up to his reputation. I wouldn't hesitate in hiring Mike again."
Dougie Pender
Projects: Tesco Delivery Dash, Imagination Challenge
"Mike's in-depth technical expertise and willingness to go above and beyond the call of duty meant that we produced a great-looking tool on-time and on-budget."
Steven Levin
Display Digital
Projects: Boots skincare consultation
"I've called upon Mike's expertise on numerous marketing projects, which he has always over delivered on. He is a pleasure to work with and we consider him as part of team Montage."
Nav Saini, Technical Director
studio montage
Projects: Viglen HTML5 website, Viglen IT banners
Selected projects
The client came to me to concept, design and build several interactive 'attractor' apps for their latest line of very large multi-touch TVs. These TVs are located in hotel lobbies, trade shows, clubs etc. They play one of the attractor apps in demo mode until a passer-by's interest is piqued and they investigate and play with attractor.
Each interactive had to intresting enough in demo mode but also highly 'touchable' and playful when a user (or multipule users) came to play. The high-end TVs have an nice Android system on-board to run these interactives.
Merseyrail wanted to clearly display 3 groups of information all on the same screen. I started from sratch designing the UI to be to be both easy to scan and easy to dril-down into the live data. The boards/screens show:
• Arrivals and deptatures for the assigned station
• Merseyrail's real-time 'trains on time' status and the rolong average from the last 2 hours, along with the national average of these for comparision.
• The current state of both lines and the four major stations along those lines.
HTML/ajax/php talking to National Rail's DARWIN live train webservice, merseyrail's own PPM and line status feeds.
Most of my work is repeat work for happy clients and agencies. Studio Montage hired me once again to add to our previous work for Viglen.
This time we needed 'hero banners' to go at the top of each of the 4 sections of Viglen's sub-site. Using HTML5's canvas and good old fashioned javascript I developed the animated banners to get the message accross.
I also pumped out the animated GIFs as a backup for the small minority without the latest HTML5 browsers.
I designed and built a roster system for Merseyrail that handles their very complicated shift patterns and rota systems for all their stations and support workers. Admin users can easily add new rotas, build shift patterns, add new people to shifts from the LDAP employee lookup system and generate shift sheets for any future week.
Designed with the user at the forefront of the UI and built using HTML, javaScript, php and mySQL.
The Post Office had a need to train their new staff in all the complicated ins and outs of manning the Bureau de change. I was hired by the Nottingham agency SpinningClock to code a responsive HTML5 game. The game... er I mean learning tool makes use of HTML5's canvas, preloads each level as needed and enhances the experience with some nice smooth animation.
The rich media experience had to be just as useable as an iPhone app but in the iOS browser. The website obviously is perfectly fine for all modern browsers on pc and Mac too as well as Android mobiles and tablets - basically the Post Office wanted employees learning all the time, whereever they were ;)
Merseyrail had a lot of staff missing out on access to their intranet because they were not in the same place long enough to log onto their desktop machines. The solution was a set of 90+ touchscreens dotted around station break rooms and driver rest stops, that had all the best from the intranet and was a gateway to more in-depth info.
The screens show lots of 'quick bite' snippets of dynamic information; the current weather direct from the MET office, line running status, latest news etc. But also have meatier servings like an LDAP powered employee lookup, 'post-it' note message system for staff comms, latest Merseyrail news stories, job vacancies, commly needed forms along with the usual high-frequency external links of Google, Network Rail, BBC news etc.
The frontend UI is built using HTML, CSS & javaScript with a PHP & mySQL backend. Fun-fact: I took a photo for each of the possable weather conditions for the weather 'tile', but it was hard to test properly as it only ever rains in Liverpool ;)
Viglen are overhauling and updating their site to the latest HTML5 technology. I was tasked by the good people at Studio Montage to create an interactive classroom makeover app in HTML5, canvas and javascript. Which shows the users how to integrate the latest ICT into their classrooms.
We had a choice of 6 classrooms to fill with all sorts of posh products, all accessible via the animated menu. The user simply dragged and dropped their chosen products into the scene, scaling them as required.
Once the user is happy with their prefect classroom, they get to save it for future reference. Or they can print or email the room to their IT dept. to get the ball rolling with a big hint ;)
The website works on all flavours of browsers supporting HTML5.
I produced a cross device mobile application for the nice people in the fashion and textiles dept. of The School of Arts and Digital Industries of The University of East London.
The app scales to fit any screen on iOS and android devices. We have lots of video and PDF content, which is browsable via the app, along with database of FAQs. I also created the CMS and database that powers this app and allows management of the videos, PDFs and FAQ items. The web service chooses the most relevant video size for the device, so we don't waste bandwidth.
The app was designed to be used offline too. Allowing the students to download the content they need, while they are on the Uni's wifi, for later use. So no more having to reply on decent wifi (now there is no excuse to not work on the tube too).
Novacroft needed 2 video emails. I worked along side a great copywriter; Tiphanie Mellor. Along with designing and building the emails, my main task was to design and animate the videos.
For the first video we needed the excitment of new year to spill over from the email while delivering the company's new year message. A second video was a lot calmer and conveyed the brand information while floating around in a spring meadow on a balmy spring day - a very relaxing job this turned out to be.
Google wanted to shout about thier new drive cloud storage system, so I produced a set of simple and clean banners that quietly shouted their message with a little humour.
Another straight-forward and quick project for CBS. I coded a nice reveal effect for the text in these banners so even if you have seen them before or see 2 on the same page, they are a little different each time. I prefer to code all animation effects if possible as it makes little things like randomly scrolling backgrounds a lot quicker to implement and scroll smoother as a bonus.
2 sets of 5 banners, along with GIF backups and a few Facebook ads all in under 2 days - everything goes nice and smoothly when everyone knows what they are doing (thanks, once again to the pros Ignition Creative) which leaves a happy client who comes back for more.
It is a bit of a web advertising cliché; a snowboarder 'breaking' out of one side of the site overlay and landing on the other side, but it was fun to do still. I got to keep my After Effects skills sharp while producing the 4 'flavoured' sets of the banners for loads of sites each. Formats included full site takeovers and pop up video banners all complemented by various leaderboard, mpu and sky units, across 2 media serving platforms.
I still think snowboarding is silly as you get cold hands and fall over a lot. Strange hobby ;)
I love the challenge of visualising massive data sets in an organic and user friendly way. Whether it be a small graphic to show loads of weather information in a single glance or creating dynamic environments that evolve as you navigate a massive database to find that useful set of data out of the 70,000+ items.
Another quick project, straight forward, nothing too complicated, just some nice animation. Another project with Ignition Creative where everything just goes to plan which keeps costs down and makes everyone happy.
The RNLI needed their e-card system completely redoing so it could handle animated covers, inside cover images or text and a few other little dynamic tweaks. It was a short turnaround and worked perfectly first time. Happy client and nice to have another great charity on the portfolio.
Dulux needed to bring the content, essence and success of their new brand exhibition in Athens to all employees and not just the ones lucky enough to be there in person. I was hired once again by the good people at DesignBridge London to produce the downloadable desktop application (runnable on both Macs & PCs) that easily showed all the in-depth content needed to deliver the brand concepts.
The project's UI was based around a 3D generated, room-by-room fly through. The viewer would navigate rooms either sequentially or via the jump navigation. Once you are in the 'room' then all the interactive points of interest animate on ready to take you to their content. Videos, poster images and pdfs are all viewable in the app or a print resolution version is ready to download.
The Ashes 2013 held an exclusive launch dinner inviting lots of big-wigs and cricket people along to Lords cricket ground. For my little part of this I built a dual platform invitation application which was sent out on a clever little usb credit card made by Goosewire. The lucky invitee puts the card into their computer and is greeted by Graeme Swann.
I also designed and built the mySQL database to capture the attendee's registration details sent from the desktop Flash application. I build several layers of error handling into the system that gracefully degraded if any problems cropped up. The dinner invitee was then sent to a little mini-site for further videos of Graeme and his chums.
They have some quality old programmes on CBS drama and they rightly wanted to shout about it in a series of expandable video banners. I built 5 different sizes of expandable banners. Once expanded the user had 4 different videos to sit back and enjoy before (hopefully) clicking through to find out more.
Ewan McGregor and Naomi Watts don't make an appearance in this little banner I built for Ignition Creative, but then I only had 50k to play with. Even with 50kb (well, I was allowed to sneak an extra 1.5k without the media people complaining ;) I still managed to use my Flash animator skills to get 6 frames of lovely smooth fading and a video background! I'd had to employ all the little video tricks to get all the content, including the video and code crammed into 33k as the media component took up over 18k before we'd started.
The Vulcans need to recolonise the planet, you are put at the helm in charge of selecting the perfect place for the construction and surveying that needs to be done on the planet's surface. Once again working with people at Harkable and this time with a great illustrator called Guy Warley, I used my Flash developer skills to create the Flash game application and good old fashioned animations (I'd almost forgot all about character walk cycles and smoke effects! It is a refreshing change to be utilised as a freelance Flash animator as well as a freelance Flash developer). A new mission was released each day of the month. My application build was nice and dynamic so handled every new day easily thanks to a nice back-end that talked nicely with the Flash game. The game supported 15 languages.
As play progressed over the days the landscape built up as the levels progressed - remember that mine we built on level 15, well it is now up and running and looks great. The user can drag around the map or just use the mini-map to click to scroll to that position. As the terrain develops my code takes into account the areas where you can and can't build or prospect anymore - there is no point trying to land your ship in the water or on the side of a mountain!
Whenever I get a spare moment I try and make a small program that helps explore an area of computational design. This is design (or art) that is created through the use of interactive/iterated algorithms. These vary from experimental interfaces to 10 minute toys. ...mostly just used to generate nice posters ;)
Working alongside the chaps and chapesses at Tangent90 once again, I built an iPad application for an undisclosed pharma company (hence the really blurry thumbnails). I developed a front end iOS application to work with Tangent 90's document vending system. The user logs in, at which point the app goes and checks the server for the documents they have access to and then the iPad application downloads all these docs ready (so we can work offline just as well). The documents (pdfs, videos, sounds clip etc.) can be viewed on the app but can also be selected to be emailed the user for further reading on their desktop.
The app handles portrait and landscape happily, relaying out the content to suit and also scales the graphics to suit the retina iPad3 or the iPad1&2.
I like being a freelance designer and developer as I get to work with lots of nice people, once again with the smart people at Tangent90 I built an AIR app that played out over a few plasma screens in the entrance of Selfridges London. The installation took pictures of everyone coming through the door, which then where cropped to a head and shoulders image (all this clever stuff done by Tangent90) which then found themselves 'dropping' into my mosaic of other customer's faces. The mosaic tiles are then colour tinted and make up a larger image of Will.i.am.
Depending which version is running at the time, we either play a promo HD video every few minutes or (my personal favourite) explode the mosaic's tiles and spin them around in 3D before putting them back in their correct places. For no reason beyond eye candy but, for once, that is what you need to attract the passers-by attention.
What could be better for Christmas than a personal video from Michael Bublé? How about two videos!
I worked with Harkable on this video mapping Facebook app. The user gets to give Michael a present to unwrap; a photo of themselves or a friend. Then a 'good' ending or a 'bad' ending is chosen depending what reaction you would like from Mr Bublé. The good ending will make every Michael Bublé fan happy as he kisses your chosen photo which I (after brushing off my video motion tracking skills) magically motion tracked into the picture frame on the Flash video in real time.
A nice little twist, which is a testament to Bublé's humour, is that you can also have an 'unhappy' ending. I won't give it away but needless to say Michael is not happy with his photo present, but it a great way to tease a non-Bublé fan, ...if you can find one.
I produced a quickly turned around Flash demo of an iPhone app for a client who had a great idea and needed a visually working run through of an iPhone program to present to potential investors to get them on board. I can't say much about the project as it is still under wraps (hence the blurry screen shots) but I can say the demo did it's job and helped win funding for the project which is now underway.
UK fishermen are not getting a fair price for their catch, Greenpeace, working with the agency Zone, decided to highlight this by allowing Facebook users to star in their own sea shanty. The experience is a pre rendered video with the user's name and profile pic seamlessly overlay onto the footage. The personalisation included a shop name,the user's profile pic blended into the pub scene and even a personalised tattoo motion tracked onto a moving arm.
Working with the agency Tangent90, I produced an application that ran on 3 large touch sensitive plasma screens to be shown at trade shows. The project was based around an infinite 'big wheel' carousel of content tiles that then clicked through to a video and some more copy. Users could save details of which content they had viewed for later review.
This luxury property site (Flash with simple html fall back) was crafted over 2 years with a 'high quality' ethos always in mind. The site runs off a CMS for most content and a bespoke XML doc for the more complicated portfolio sections.
Working once again with very nice people at Yomego design agency I created this Facebook app for Tesco. The player gets to play the part of unsung heroes that pack your online delivery by grabbing the items from a conveyor belt of products for 4 customers at the same time.
Each level gets faster and harder which would be OK if it wasn't for the random punctures and heavy traffic! Strangely addictive and I'm still not sure why, but then again I don't understand shopping either ;) Statistics time:
-100k plays in (just over) the first month
- the average user playing 16 times
- nearly 200 players playing the game for over 6 hours (100+ times)
- 1 player has played over 1200 times, that is nearly 3 days worth of game play!
With so many people playing such a 'sticky' game it is a good job we tested thoroughly before turning it out into the wild.
Working once again with the nice people at MediaCom I created a custom YouTube front end to EA Sport's FIFA channel. The videos, thumbnails and copy were all served up from MediaCom's back-end via XML which also controlled the tabs. All-in-all leaving EA with an easy to update and flexible custom channel which they update constantly.
Working with the guys at yomego Scotland I built a nice little user generated content viewer. All the user's competition entries can be filtered by location and then the app selects a random selection of entries from that location to display. Some are videos, some are images, some portrait and some landscape - the app handles them all.
Thanks to yomego's Facebook API, we also were able to use the app to view the user's Facebook photos.
The client needed to place the project on different sites at different sizes so it is nice and scalable to fit any size that gets thrown at it :)
A lot of banner projects are straightforward enough, no boundary push and no bleeding edge, just simple and effective animation that helps the message get across. I produced a set of banners for FedEx, a few sizes each for 2 regions.
Two facets to the same project here. First is a set of banners for Fujitsu's 'cloud' computing solution. The second I had to dust off the old Photoshop skills and produce a mock up of a live projection animation.
Sometimes it is nice just to do some old skool animation. For the Cabana website I dusted off my After Effect skills and made a 3D animated menu in the style of window shutters. I put this into a little Flash wrapper and made a menu for the homepage of the site.
Dotted around the site are little animated drawings. I just couldn't help myself with these anims though and ended up animating a lot of them with code so they were different each time the user came back. I don't like the punters getting bored!
I've made 5-6 versions over the years of this project to show off Warner Bros' back catalogue of children's DVDs. Each time adding a little here and there, sometimes adding a game or a little piece of interaction. The latest version got a conveyor belt and robotic arm and user controlled mood lighting, ...I can't quite remember why now.
Airbus only wants the best and most suited graduates for their training programs and jobs. Working with Digital Mosaic's designs, I built this career path chooser which took the applicant on a journey of 5-6 questions and then suggested the best area of the Airbus group to apply to.
An XML based decision maker and some slick 3D tilting and panning makes this project stand out from the usual recruitment tool.
Drayton Manor have a new ride opening - the Ben 10 Ultimate mission ride - and they wanted to tell the target audience about it, well any of the audience that are over 1.2m tall. So I was hired by my friends waste creative to make a mini-site in the Ben10 flavour with the usual info about Drayton Manor and a nice little 'being on a roller-coaster while shooting at baddies' game. Can you guess what the new roller-coaster ride is like? ;)
Once the user has followed a link from a placed YouTube video, they are granted access to Mi5's computer system giving users the chance to become a 'spook'.
I helped design the UI and the mini-tools. I built it in a slick manner with sliding and semi-opaque windows so the user felt they were peeking into classified documents in order to find out who they could trust.
'Chris Moose' quiz (say it in a Scottish accent to get the pun ;) was a quick little quiz I coded for the Scottish agency JamHot. The questions are from a big XML set of varying degree of difficulty and all the text was updateable by the client at any time again via XML. Chris Moose has a lot to say so I got the chance to dust off the animation skills for Chris when he is giving feedback and talking. The quiz also has a PHP/mySQL high score system, which I built to complete the package.
Working once again with Waste Creative I coded this little mini-site in super quick time time ready for all 15 languages and 100,000's of fans wanting to know about the latest in the Ben 10 line - the 'ultimate alien'.
The site has videos, games, Ben10 facts, favourite alien voting results and even loads of masks you can download and print out :)
HSBC wanted a presentation tool to introduce the speakers of a major conference. The tool had to scale and work with 56" plasmas as well as touch screens and had to be updateable on the day by the people presenting it. So I built a presentation that scaled perfectly and was easily updateable via XML at any time, it was just what they needed.
To highlight F-Secure's anti personal identity theft program, I created a Facebook app that showed a video of John dropping his credit card on the floor for anyone to play with. The video then zooms into the card and the details warp into the Facebook user's own name to highlight they may need F-Secure's product too.
I created an hero product viewer for the main pages of kittydolittle.com. The viewer takes any number of products and lays them out in space to fit nicely and then shows each product at once with some nice animation. Simple and effective.
I was tasked by Random42, a specialist biological 3D rendering outfit in Soho, to show off their new high-definition molecular animations. Luckily I didn't have to understand any of it.
Scottish agency Chunk tasked me with building 3 Flash games for inclusion in Cadbury's new online children's book and activity website.
I created an animal piano game where we get to play follow the leader and copy a well know song or the player can just freestyle. The next mini game was a jigsaw game. But not just any jigsaw game, this one has advanced snapping to groups to aid the building process - just like you would with a real jigsaw. The last game was a nice and simple 'painting by numbers' type game where you colour in the supplied line drawing - no worrying about going outside the lines here :)
We are the people movie is about the state of education in Britain. The site is a massive 2D parallax of 'paths' which the user follows around. I coded the movie's site to a short turn around. It has quite a few talking heads with people like Richard Branson and Henry Winkler ('the fonz' oh yeah).
Virgin wanted to point out to everyone that they are better than Sky. They wanted to show, in an engaging way, all the breadth of content and cool stuff they have like video on demand and pausing live TV.
Virgin wanted it to be better than the 3D video fly through that Sky have (which amused me as I made the Sky one a year earlier). This was a short turnaround project, just under 3 weeks, as Virgin had a two stage launch plan. But thanks to the great people at Spike/Elvis and the freelance creative art direction from Jim managed to do near enough everything they wanted for stage two but by the stage one deadline.
I coded 2 in banner games for the launch of GI Joe the movie. In HALO dropzone you take control of our hero as he jumps high altitude and avoids the sky mines and flak on the way down. In Tank Commander you get a tank to fight your way through the village and out to safety.
A few cool extra touches on these games are the smoke fumes that change colour and opacity based on the revs of the diesel engine and the real physics of the drive tracks. No one asked for them, and it's a bit geeky, but I like it.
DTP's Summer athletics 2009 and Duracell got together and wanted an online experience to drive awareness of the game's launch and the new rechargeable batteries for the bunny ;)
I coded the 4 events from the main game each with a bespoke game engine and control system to give the player a taste of what was to come on the Wii.
Gucci's high standards were evident throughout the attention to detail in this project. My Flash dev skills were needed by agency Critical Mass to create highlights like the interactive 3D fly through of the 'flora' motif's history. I was also tasked with everything from html to After Effects work when needed.
Quote Exchange wanted a fun way to lighten up the business of the quote comparison world. I coded in Flash, a little world which allowed the users to explore the offered content while being entertained and charmed.
I added nice little touches on top of the content exploration to make sure the user was there out of choice; little things like the working toaster (jam sold separately) and some movable fridge magnet letters - my record is 4 rude words.
The M&M'S Full colour gaming site was for cross promotion with EA games. So I was tasked to develop 3 games along the lines of EA's finest... but using M&M's rather than golf balls or cars!
I made 3 little physics based games where the track was destructible and the golf ball has a flight path O'meter and amfPHP highscores tables.
You 'crunk off' (dance off for oldies ;) against the computer or challenge your friend (via email) to compete in a turn based game.
I designed this trolley dash game for Kodak (while freelancing at OgilvyOne) and had nothing to do with the build at all! - bit of a change from usual. The idea was to teach people about the package deals they could get from buying bundled products whilst having a bit of fun.
A lifestyle website to give info and aspiration for the 'Elegance' perfume from Proctor and Gamble. The site is in five languages, including ru_RU.
Polaroids are flung on the floor of a young lady's apartment. The user zooms in and around the polaroids, finding video clips as they go, to explore the 5 stages of getting a cold sore.
Unilever wanted a 'bendy' empty toothpaste tube to show that the container can be recycled into various objects. So the MPU is a timed game allowing the user to bend the tube to make chairs or roofs.
Marks and Spencer wanted a easily updated image viewer and links for the homepage. The 'hero image' viewer sits in prime spot on the homepage and is updateable via their CMS. There is also a video player version.
Fimbling Fun! is a CD-ROM for fans of TV program aged 2-6. I acted as head programmer on this project, making all the technical demos in the early stages. This was a lot of fun to work on as the Fimbles are so cute :) I am very proud of being able to name all the Fimbles and their friends without having to think about it.
At the BBC's interactive TV design department, I designed and built interfaces and models for current and future interactive TV services as part of the 'Future Interface group'.
This ranges from simple 'now and next' type screen overlays to imagining future interfaces for the next gen. of digital personal recorders which need to allow browsing and searching of 70,000 data items.
Commissioned by the DTI for the Sunday Times newspaper. There are over 400+ articles over both CDs, these all come from a rational database on the discs. Each article has photos, diagrams or video clips to accompany it.
4.5 million discs were pressed and, along with being on the cover of the Sunday Times, they were also sent out to all schools in the UK & commonwealth.
This is a very dynamic project, that even generates graphic elements from the data. There is a full weighted search on both CD-ROM.
Developed for the Royal Institute of Great Britain. from some of my game concepts. The InsideOut website is designed for 11-14 year olds to help inspire them to science. I created 3 games for the site, Human Cannonball, Energy Quest and Flick the Flea.
The InsideOut site was showcased in DIGIT magazine and BAFTA nominated.
From my original interface concept UI design, I produced an exciting learning tool for 11-14 year olds to learn about the UK and it's places of interest they can visit. The spinning menu and zooming map are an exciting way into the roughly 2000 pieces of database driven content. This flagship application of www.gridClub.com helped the site walk away with a BAFTA, a BETT and an Emma Foundation award.
I produced 4 children's games as part of Channel 4's 'What If?' website, supporting the TV show of the same name. The games taught basic maths in an entertaining and transparent way.
The What if? website was in support of Channel4's What if? Children's TV program.
A rather dark Christmas viral email game where you play the part of a snowman who throws snowballs at other snowmen, whilst trying to avoid smashing the windows! This was a great project where my only brief was 'we need a game to go out via email and you have two weeks to do it in.
visit me on Facebook/freelanceFlashDesigner
Visit me on Linked.In
I'm also on peoplePerHour
Visit me on Twitter too (although it is a bit lonely there, apart from the robots)
...but don't even bother visiting me on Google+
unless you like looking at a blank wall and talking to yourself ;)
Copyright ©1997-2016 Mike Rigley


text:
You already know enough. Have a firm grasp of vectors and keep making games.
If you eventually need something more it will be specific to your project, and you can learn it then.
desdemianMember Since 19 Sep 2004
Offline Last Active Aug 28 2016 12:29 PM
Community Stats
- Group Members
- Active Posts 63
- Profile Views 7,466
- Submitted Links 0
- Member Title Member
- Age Age Unknown
- Birthday Birthday Unknown
Not Telling
Contact Information
- Website URL http://www.stochasticlints.com
1581 Alpha


text:
Geneva Airport has been closed since this morning due to heavy snow falls. This is the first time since 1985 that the airport has had to close like this. If possible, passengers were sent by train to ZRH where flights are still operating normally.
The charter flights should operate tomorrow, and the airport could reopen at 4pm today.