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Spitfire build - Maximizing damage with Electrocution
View Single Post
ggFTW Stalker
Join Date: Apr 2009
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IGN: ColdShadow
Class: Yuki
Spitfire build - Maximizing damage with Electrocution
AradSociety - Skill Planner
I decided to try something different from the typical Spitfire build of Max Freeze and Blazing Bullet, and max Freeze Grenade.
Instead, I decided to go for max Freeze, max Flash Bang, and max Blazing Bullet. I decided against maxing Freeze Bullet, because the freezing rate is low and unreliable. The magic damage is still decent at level 5, so it's not completely useless.
However, I found the electrocution rate for Flash Bang high enough, so I'm maxing it for that. Electrocution = extra light element dmg for each hit, so I thought Flash Bang would increase my overall damage output more than maxing Freeze Bullet would.
Blazing Bullet is just maxed because the total damage increase per level is decent with the extra explosions multplying the damage.
I decided to get Cancel - Grenade because it's a steal in terms of SP. I can use the G-18 Buster as a second height raiser in place of Rising Shot cancel, or I can use a Freeze Grenade in PvE when a second mob is coming up to interrupt me.
I replaced Steyr AMR with Flamethrower, because Steyr AMR is mainly used for ranged dmg and pushback. I thought that Crossmore already accomplishes the distancing part, and Land Runners would suffice to annoy from a distance. Flamethrower gives quick hitstun, even when just pulled out and cancelled immediately, so I thought I could use it to get a quick grenade in.
Any thoughts or concerns?
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Fabric and color of this item may vary in our showroom.
Belfort Furniture offers White Glove in-home delivery and set-up by professionally trained personnel who will unwrap, place, and assemble your furniture in the appropriate room. Delivery is available Tuesday - Saturday. Once your delivery date is scheduled, you will receive a three hour delivery timeframe the day prior to your delivery.
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Christopher Young (music composer)
~ Person
- For other persons named Christopher Young, see Christopher Young (disambiguation)
Christopher Young (born April 28, 1958) is an American music composer for both film and television.
Many of his music compositions are for horror films, including Hellraiser, Tales from the Hood, A Nightmare on Elm Street 2: Freddy's Revenge, Urban Legend, and Drag Me to Hell. Other works include Lucky You and Spider-Man 3, for which he received the Film & TV Music Award for Best Score for a Dramatic Feature Film. He also made three cameo appearances in Spider-Man 3.
Young was honored with the prestigious Richard Kirk award at the 2008 BMI Film and TV Awards. The award is given annually to a composer who has made significant contributions to film and television music.
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With a stay at Ela Beach Hotel & Apartments in Port Moresby, you'll be near the beach and close to Lloyd Robson Oval. This hotel is within the vicinity of Hubert Murray Stadium and Parliament House.
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Suburban Survival Blog
I work from home remotely from my company's office. It is a curse and a blessing. I can get a LOT done in a shorter period of time because almost as soon as I wake up, wipe the sleep out of my eyes, I am at work… When I need some flex time to go […]
Tagged as:
Physical Fitness,
I recently heard of a man called Fernando "Ferfal" Aguirre from Jack Spirko over at The Survival Podcast. Ferfal is from Argentina and has lived through their economic crash from December 2001 until today. He wrote a booked about his experience called Surviving The Economic Collapse. He also has a blog called The Modern Survivalist. I […]
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first aid,
Gold and Silver,
Guns / Weapons,
Levels of Awareness,
Physical Fitness,
While on and off my fitness kick this year, I have supplemented my daily diet with a morning protein shake mixed with fat free milk, water, ice, and various fruits that would mix with protein powders well. I have been on the quest for the perfect protein powder with no real success, although Muscle Milk, […]
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Food Storage,
In a survival forum, it was noted that: "Remember the first rules from Zombieland. No, not "double tap." Cardio. If you're a couch potato you need to fix this right now." Yes, I am a former athlete that has been a couch potato for too long. I am also above 40 and overweight. But this […]
Tagged as:
Physical Fitness
Well, after last evening's interview with Doctor Prepper, I thought I would write up a few thoughts on planning for your preparedness goals. This will probably appeal to novice preppers, but it got me thinking about a few points of discussion around how to get the ball rolling and keep your head on straight at the same […]
Tagged as:
bug out bag,
Physical Fitness,
Preparedness Budget,
survival plan,
Yes, it's true. I am already failing to accomplish my 2011 fitness goals. I blame part of it on my new job. I am out of the house before 7:00 a.m. each morning. Big deal, right? A lot of you reading this could be out the door at 5:00 a.m., I am sure. I also […]
Tagged as:
Physical Fitness,
Well, what a week it has been. The crazy news, the weather here in the northeast, work is crazy, and the weekend is going to be about catching up and be just as nuts. Currently, I am in the process of reading a book by Scott B. Williams called "Astray of the Herd: Observations, Commentaries, […]
Tagged as:
Les Stroud,
Natural Disasters,
Savage Model 24
Wow, the new job is certainly keeping me busy. So busy in fact that I have not had the time to write much the past two weeks… Not really what I had planned on, but you have to make hay while the sun shines as they say.
Tagged as:
I just read a blog post on Doctor Prepper this morning ab0ut healthier eating. I try to eat healthy, but if you saw me eat on a business trip, you might think I was addicted to steaks or a junk food junkie. Sad but true. I can say that I probably gain a couple of […]
Tagged as:
This is really just a quick blurb. Recently, I have been back at the gym. It has been an interesting ride, getting back to the gym after 10 years of letting my health go. I am by no means obese, but my lung capacity and strength were minimal compared to years ago spending five and […]
Tagged as:
suburban survival,
Urban Survival
← Previous Entries
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Software Licensing
From ITS Wiki - Information Technology Services - University of Rhode Island
| Services
This page is part of a category. To see more pages like this, go to the Services index.
Starting July 1, 2014 Microsoft, Adobe and Apple software will be sold though Ram Computers (401-874-2679) Thank you.
At URI, departments can purchase the following software for installation on URI property computers. For more information go here: https://ramcomputers.uri.edu/shop-software/software-licensing-for-the-institution. Ram Computers phone: 401-874-2679
Windows Software
- For Microsoft and Adobe products contact Ram Computers 401-874-2679.
- Key Server $20
- Geographic Information System (ArcGIS): variable (see below)
Macintosh Software
- For Microsoft and Adobe products contact Ram Computers 401-874-2679.
- Key Server $20
Purchase Software
To request no-cost software (except Oracle), please go to the following site for more instructions. http://web.uri.edu/its/statistical-software-site-licenses/
To purchase software (Microsoft or Adobe) contact Ram Computers 401-874-2679.
Geographic Information System (ArcGIS) for Windows:
- URI offers the Basic, Standard and Advanced product levels. There are also extensions available for ArcGIS. This software is available only to URI faculty and staff; it is licensed annually to the University.
For more information on the GIS Software Site License, please see: Geographic Information System (GIS) Software Site License Application.
Application Description: Mathematica is renowned as the world's ultimate application for computations. But it's much more—it's the only development platform fully integrating computation into complete workflows, moving you seamlessly from initial ideas all the way to deployed individual or enterprise solutions.
Eligibility: Faculty and Staff on URI property machines and personally owned machines.
Further information on obtaining Mathematica software at URI is provided by clicking on the Mathematica software link.
Statistical Packages
SAS for Microcomputers
System Platforms: MS Windows 2003, XP, Vista (XP and Vista Home edition is not supported), and Linux
Application Description: Tools for data management, data retrieval, report writing, graphics, and statistical analysis
Eligibility: Faculty, Staff, and Graduate students on URI property machines only.
Link for more information on applying for a license: http://web.uri.edu/its/statistical-software-site-licenses/
SPSS for Microcomputers
System Platforms: Windows XP, Vista, and Mac OS X 10.4 (Tiger) or Mac OS X 10.5 (Leopard)
Application Description: Tools for data retrieval and statistical analysis
Eligibility: Faculty and Staff on URI property machines only.
Link for more information on applying for a license: http://web.uri.edu/its/statistical-software-site-licenses/
Respondus is site-licensed for URI faculty, staff, and students. It is for Windows only.
To download the software and annual access code, go to https://sakai.uri.edu/access/content/group/11d56ab0-7073-498d-a9bf-20edd8ae203f/Respondus_StudyMate-1.htm.
Dell Contact Information
For users looking for software that is not offered at the URI Computer Help Desk, please contact the following:
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Chaz Denton
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Contacts, Map & Directions
- Details
- Category: About Us
Mindekirken – The Norwegian Lutheran Memorial Church (View Map)
924 E. 21st Street
Minneapolis, MN 55404-2952
Church Office: (612)874-0716
Fax: (612)874-1971
The Church office is open Tuesday through Friday, 10:00am – 3:00pm. Outside these hours, there is a voice mail system on which you may leave a message for any staff member or in the general voice mail box.
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On weekdays, please do not park in the Wings Financial parking lot.
Special Contacts
To find phone numbers and email addresses of specific staff members , see Our Staff page


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With a stay at Palazzo Versace Dubai in Dubai (Bur Dubai), you'll be convenient to Dubai Festival City Mall and Dubai Tennis Stadium. This 5-star hotel is within close proximity of Festival Center and Dubai Creek Golf & Yacht Club.
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| View Exclusive AAUP Compensation Survey Data |
A federal task force convened by President Obama takes government enforcement even further, but promises to consult with college officials this time.
Amid persisting confusion about when colleges can involuntarily remove a self-threatening student, Education Department again signals it's not permissible -- in an investigation that ends in a student's suicide.
Florida appeals court rules that, in most cases, public colleges and universities can't regulate weapons on campus.
Montana didn't ask to be the national model for sexual assault response, but after a series of alleged rapes, the U.S. government made it so. Staff members and students adjust to expansive policies and a spotlight that isn't dimming.
The firing of a Swarthmore resident assistant who accused the college of mishandling sexual assault -- but would not reveal details of a case -- highlights nuances of students as mandatory reporters, a growing issue.
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In wake of the Boston Marathon bombings, some colleges have already strengthened security measures. Experts urge revisiting emergency procedures, but caution against overreaction.
A University of New Hampshire lecturer is dismissed after administrators question medical decisions she made leading a trip to Nicaragua. She says she could have used more support from the institution -- not condemnation.
In canceling classes after a reported Klan sighting that still hasn't been confirmed, Oberlin says context was everything.
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text:
realmagick.com The shrine of knowledge.
The Lover Plot Summary
A selection of articles related to the lover plot summary.
Original articles from our library related to the The Lover Plot Summary. See Table of Contents for further available material (downloadable resources) on The Lover Plot Summary.
- The Aeonic Perspective of the Enochian Temples
- The initiatory system of the Enochian Temples divides the path of initiation into four major stages, distinguished primarily by the types and sources of the influences they are sensitive to. Briefly, these stages are: 1. Lunar-planetary, focused in Yesod and...
Magick >> Enochian
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Mystic Sciences >> Astrology
- Mother Of The Gods And The Father Of The Gael
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Deities & Heros >> Celtic, Welsh, Irish & Brittish
- Select Cross-Cultural and Historical Personifications of Death
- This extensive introduction includes some of the more well known, along with some lesser known Death "incarnations", and I use that term loosely, as in many cultures, the Angel of Death can be quite an adept shapeshifter. We have tried to cull...
Mystic Sciences >> Necromantic Studies
- The Celtic Vedic Connection, Part I
- Of all the great ancient cultures perhaps no two share more parallels than those of the Celtic and Vedic peoples. A deep rooted affinity runs between them, what is present in one is mirrored in the other. Myths, Gods, Goddesses, even fairy tales bear a...
Religions >> Druidism
The Lover Plot Summary is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, The Lover Plot Summary books and related discussion.
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- Long live ENO!
- In Bellini's Norma things are more complicated: Norma's faithless lover Pollione joins her on the pyre in a shared purgation while the Druids regard them both with horror. It would be absurd to say which of these is ...
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- You should all be watching American Crime Story: The People v OJ Simpson. Based on the high ratings, a lot of you are watching the FX drama, but if you're not, you should check out the very addictive, fun and thoughtful drama, which features a great ...
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
The Lover Plot Summary Topics
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Seahawks.com Writer
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Wednesday in Hawkville: Seahawks add depth at tight end by signing Kellen Davis
Latest Video
Watch as a young fan gets emotional over former Saints tight end Jimmy Graham after he was traded to the Seattle Seahawks last season. Watch
Seahawks defensive end Michael Bennett spoke with the media leading up to Seattle's Week 8 matchup against the New Orleans Saints. Watch
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Seattle receiver Tanner McEvoy signed autographs at the Seahawks Pro Shop for Junior 12s Kids Club members on Tuesday, October 25. To learn more about the Junior 12s Kids Club, go to Seahawks.com/KidsClub View
A recap of the activities at Virginia Mason Athletic Center for Sept. 11, when the Seahawks began practicing for Sunday night's nationally televised home opener against the San Francisco 49ers at CenturyLink Field: Read
The Seahawks decided they needed it at the tight end position, so Kellen Davis was signed to join starter Zach Miller and rookie Luke Willson.
"It's somebody we definitely need for our depth at the position," offensive coordinator Darrell Bevell said after practice on an unseasonably warm afternoon along the shores of Lake Washington. "We only had two and something could happen real fast, so we need to start training somebody to start to get them ready."
That somebody is Davis after he impressed the coaches during a workout on Tuesday.
"He had a good workout. I like what we saw in the workout when we were deciding if we wanted to sign him," Bevell said. "I liked the way he ran around, caught the ball real easy."
Davis, who turns 28 next month, played in 80 regular-season games the past five seasons, catching 47 passes for 529 yards and 11 touchdowns, after being selected in the fifth round of the 2008 NFL Draft. He was with the Cleveland Browns in training camp this summer after being released by the Bears in March, but the Browns released him Sept. 1 on the final roster cut.
Davis displayed the ability to get open and catch the ball during his first practice with the Seahawks.
"I like what I saw," Bevell said. "But it's still really, really early."
To clear a roster spot for Davis, backup middle linebacker Allen Bradford was released. Read
"Our guys love playing here and they love being part of it. It's a great spectacle. The No. 1 thing this week is we get to come home and play football here."
Pete Carroll on playing at CenturyLink Field, where the Seahawks were unbeaten last season. Read
The first official report of the week, as issued by the team:
Did not practice
CB Brandon Browner (hamstring)
DT Jordan Hill (biceps)
S Jeron Johnson (hamstring)
NT Brandon Mebane (ankle)
Limited in practice
DE Cliff Avril (hamstring)
OT Michael Bowie (shoulder)
DE Chris Clemons (knee)
WR Sidney Rice (knee/hip)
Full participation in practice
TE Luke Willson (oblique)
Walter Thurmond continued to work at right cornerback for Browner, who missed the season opener; while D'Anthony Smith replaced Mebane.
For the 49ers:
Did not practice
RB LaMichael James (knee) Read
Two of the players selected in the seventh round of this year's draft were re-signed to the practice squad – guard Ryan Seymour and defensive end Ty Powell. They had been released last week to clear spots on the eight-man squad for wide receiver Tyrone Walker and defensive end Jameson Konz. Read
Russell Wilson's 25-of-33 performance against the Panthers on Sunday produced the third-highest passing percentage in a Seahawks season opener behind a couple of efforts by Matt Hasselbeck. Wilson's first 300-yard game in the regular season was even more impressive when you consider he started 1 for 5 before finishing 24 for 28 (86 percent). Here are the top-percentage performances in the team's 38 season openers: Read
With Seymour and Powell returning, two other rookies were released – offensive lineman Jared Smith and defensive tackle Michael Brooks. Read
Last season, the Seahawks played one against the 49ers when they had Pro Bowl defensive line Justin Smith and one game when they didn't.
oincidence or not, the results were staggering. During Week 7 game in San Francisco, with Smith in the lineup, the Seahawks failed to score a touchdown for the only time last season in a 13-6 loss. During a Week 16 game at CenturyLink Field, with Smith out because of an injury, the Seahawks' offense scored five touchdowns in a 42-13 victory.
"He makes a huge difference," Bevell said. "He's one of the leaders over there. He's been playing a long time. He's very savvy with his technique. He gets great push. He does some really nice work with the games with Aldon (Smith, who has 35 sacks the past two seasons to share the NFL lead). Now they're moving Aldon around, they're moving Ahmad (Brooks) around as well. So Justin is able to help those guys and free them up." Read
The players will be back on the practice field on Thursday afternoon, or "Turnover Thursday." The Seahawks had two turnovers in their opening-day win against the Panthers and one was a big as they come as All-Pro free safety Earl Thomas forced a fumble late in the fourth quarter that defensive tackle Tony McDaniel recovered at the Seattle 8-yard line.
Also, at 12:12 p.m. on the 12th day of the month fans are encouraged to raise a 12 Flag. There will be a rally at Renton City Hall starting at 11:30 and Mayor Dennis Law will run a 12 Flag up the pole at 12:12. A 3,000-square foot 12 Flag will be pulled behind a plane along the I-405 and I-5 corridors from noon until 2 p.m. Read
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© Seattle Seahawks 2016. All rights reserved. ® SEAHAWKS, SEAHAWKS LOGO, SPIRIT OF 12, WE ARE 12, BRING ON THE 12, LEGION OF BOOM, 12 and 12S are trademarks of the Seattle Seahawks. ® The term 12th MAN is a trademark of Texas A & M University and its use is pursuant to a license agreement with the university.


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The Impact of the New Regulatory Guidance Landscape on the Validation of the Manufacturing Process and the Characterization of Starting Materials, Drug Substance and Drug Product
Steffen Gross, Ph.D., Head, Monoclonal and Polyclonal Antibodies, Paul-Ehrlich-Institut - Biography
The regulatory guidance landscape regarding biological products changes rapidly. Documents overseeing process validation is currently facing major overhauls. New guidelines are published defining the requirements for starting materials and excipients. This might have a deep impact not only on the process development of traditional monoclonal antibody type products but also on new antibody formats such as conjugates as well as on new developed formulations.
Current Progress with Armed Antibody Products
Dario Neri, Ph.D., Professor, Chemistry and Applied Biosciences, ETH Zurich - Biography
There is an emerging trend in Pharmaceutical Biotechnology to "arm" antibodies, capable of selective localization at the site of disease, with suitable therapeutic payloads (e.g., drugs, cytokines, radionuclides, a second antibody moiety, hence producing a bispecific product). This strategy aims at concentrating therapeutic agents in diseased part of the body, while sparing normal tissues. In this lecture, I will present a comparative evaluation of different classes of armed antibody products, developed in my laboratory in collaboration with Philogen. In particular, I will present preclinical and clinical data of armed antibodies in the field of cancer, of chronic inflammation and of endometriosis.
Playing Catch-Up with Escherichia coli: Using Yeast to Increase Success Rates in Recombinant Protein Production Experiments
Roslyn M. Bill, Ph.D., Professor, School of Life and Health Sciences, Aston University Birmingham - Biography
This presentation highlights the benefits of using yeast for more challenging targets such as membrane proteins. We've seen advances in understanding how a yeast cell responds to the stress of producing a recombinant protein and how this information can be used to identify improved host strains in order to increase functional yields. I argue that S. cerevisiae and P. pastoris should be considered at an early stage in any serious strategy to produce proteins.
Next-Generation Cancer Treatment using Multi-Specific Darpins
H. Kaspar Binz, Ph.D., V.P. & Co-founder, Molecular Partners AG - Biography
Precision oncology is an emerging treatment paradigm by which well-chosen targeted therapeutics will inhibit the specific tumor drivers of each patient. Such an approach will require the combination of several targeted therapeutics, which may be hampered by overlapping off-target toxicities and economic reasons, or ideally the availability of multi-specific therapeutics - a natural setting for DARPins given their high specificity and modular architecture. We have generated multi-specific DARPin drug candidates against various tumor drivers, which compare favorably in preclinical models to available standards of care. Insights on the rationale for target choice, drug format, mechanism of action and differentiation will be provided.
RG7787 - A Cytolytic Fusion Protein Based on a De-Immunised Variant of Pseudomonas Exotoxin (PE)
Klaus Bosslet, Ph.D., Head, Discovery Oncology, Roche Pharmaceuticals, Penzberg - Biography
Development of immunotoxins into actual drugs has been hampered by their immunogenicity and off-target toxicity, particularly vascular leak syndrome. Together with Ira Pastan's lab at NCI we have developed a new cytolytic fusion protein format that is de-immunized and has much reduced off-target toxicity. Cell viability assays show that RG7787 has similar cytotoxic potency in a variety of cell lines as well as similarly strong efficacy as the immunogenic Mesothelin targeted PE38 from NCI (SS1P) even in slow growing tumor xenograft systems.
Safety Challenges and Risk Mitigation Strategies to Develop Immune Activating Biologics
Rakesh Dixit, Ph.D., Vice President, Research and Development, Safety Assessment, MedImmune LLC - Biography
This presentation will cover: how immunotherapy may result in autoimmune and off-target toxicities to self versus tumours; combining immunotherapy with other agents; how to maximize the efficacy and balance safety vs. efficacy; measures to streamline the combined approach and reducing toxicity to self; and strategies to risk mitigate safety concerns with the immune activating biologics and their combination.
Protein Inactivation in vivo in Intrabody Expressing Mice
Stefan Dübel, Ph.D., Director, Biotechnology, Technische Universität Braunschweig - Biography
We demonstrate for the first time that endoplasmatic reticulum retained antibodies ("intrabodies") can induce a knock down phenotype in transgenic mice. The phenotype found in adult mice expressing VCAM1 intrabodies included aberrant distribution of immature B-cells in blood and bone marrow. The availability of our technology and the rapidly growing number of available antibody genes will spark a new level for the functional study of membrane and plasma proteins in vivo.
High-Throughput Construct Screening Approaches and Rational Strategies for Kinase Structural Platform Establishment: Case Studies of Difficult Kinases
Jacques Dumas, Ph.D., Head, Protein Production, Vitry Biologics SCP, Vitry Research Center, sanofi - Biography
sanofi has a long experience in kinases for medicinal chemistry projects, with more than 90% success in crystallization. However several kinases are still very difficult to obtain. Recently we started a collaboration with EMBL Grenoble which established a platform called ESPRIT (Expression of Soluble Proteins by Random Incremental Truncation) allowing the selection of tracks of soluble constructs in E. coli. We further pursue within sanofi our efforts in expression and purification optimizations.
Cell and Process Engineering Strategies to Cure Cellular Aggregation of a Difficult-to-Express Fusion Protein
David C. James, Ph.D., Professor, Chemical & Biological Engineering, University of Sheffield - Biography
Based on kinetic modeling of the cellular synthetic process, we compared different strategies (cell engineering, modulation of culture environment) to alleviate cellular aggregation and the associated poor expression of a recombinant Fc-fusion protein by CHO cells. Our analysis serves as a paradigm for multivariate optimization of DTE protein production.
Characterizing and Release Testing of Protein Aggregates in Biologics
Ewa Marszal, Ph.D., CMC Reviewer, Division of Hematology, Center for Biologics Evaluation and Research, U.S. Food & Drug Administration - Biography
Protein aggregates in biologics present a quality issue and raise safety concerns. Thus, their content should be minimized and controlled. This presentation will cover recent guidelines for particulate matter control and the advancements in particulate matter detection and metrology.
New Applications of Phage Display
John McCafferty, Ph.D., Co-Founder, Director and CEO, IONTAS Ltd. - Biography
Construction of libraries of binders displayed on the surface of mammalian cells will allow the screening of millions of clones by flow sorting while providing information on both the level of expression and the extent of binding within individual clones. The main limitation to achieving this has been the inability to construct large libraries containing 1-2 antibody genes/cell. We have solved this problem by directing the integration of antibody genes into a single genomic locus through the use of site-specific nucleases. The presentation will describe construction of libraries of millions of clones and selection of binders including antibodies formatted as IgGs.
Development of High-Throughput Selection and Screening Methods
Jonas V. Schaefer, Ph.D., Head of High-Throughput Laboratory, Department of Biochemistry, University of Zurich - Biography
With the help of technology developments, a robust pipeline could be established that already generated valuable DARP in binders (Designed Ankyrin Repeat Proteins, an alternative scaffold), not just covering a variety of different targets but also meeting the high quality criteria important for most scientific projects: monomeric binders that specifically recognize different, non-overlapping epitopes at their targets with high affinities and which can be expressed at high levels in bacterial systems.
Philosophy and Principal Dogma behind Modern Discovery & Development of Biologics
Ralf Schumacher, Ph.D., Site Head, Large Molecule Research, Roche Penzberg & pRED - Biography
This talk will examine challenges facing the industry today, e.g. recognition of redundancy of pathways; the understanding of the signalling and interaction between cells and organs, e.g. what is responsible for suppression of immune response to a cancer and how it can be overcome; the importance of linking together deep biological understanding, disease understanding, and MOA for targeted therapies, companion diagnostics for stratification of patients and clinical study design. Examples will be provided.
The Mechanism of Complement Activation by IgG Antibodies
Janine Schuurman, Ph.D., VP, Research, Genmab - Biography
Complement activation by antibodies is an important mechanism in immune defense and immunotherapy. Using x-ray crystallography, mutagenesis studies and cryo-EM tomography, we revealed that IgG antibodies form hexamers on the cell surface following antigen binding. Enhancing hexamerisation on the cell surface by using the HexaBody platform potentiated the intrinsic killing capability of antibodies in in vitro, in vivo and ex vivo models.
CHO Cells and Processes for Antibody Manufacturing: Convoluted History and Insights
Florian Wurm, Ph.D., Dr. rer. nat., Professor of Biotechnology, Swiss Federal Institute of Technology Lausanne (EPFL) - Biography
"Superstar" CHO are THE production system for therapeutic rec-proteins. Sequencing of one CHO cell genome (2013) has extended our knowledge established in the 1960s and 70s. What made CHO cells so popular? The talk will cover the "prehistory" of CHOs as well as key insights and key opportunities that have emerged during the 30 + year biotech history of these cells.
2014 Sponsors
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Engineering Stream Display of AntibodiesEngineering AntibodiesEngineering BispecificsAntibody-Drug Conjugates
Therapeutics Stream ImmunotherapyAdvancing BispecificsNovel Therapies for Cancer
Analytical Stream Optimisation & DevelopabilityAnalytical CharacterisationAggregates & Particles
Expression Stream Protein Expression TechnologiesOptimising ExpressionPurification Technologies
Training SeminarsProtein Expression TechnologiesIntro to Protein Engineering
Short CoursesCancer ImmunotherapyMutation and Selection StrategiesDesigning AntibodiesTransient Protein ExpressionAntibody ConstructsEngineering Bispecific AntibodiesProtein Purification StrategiesProtein Aggregation


text:
This product is not currently available in Canada.
This product is not available in Canada.
Best solution for higher-traffic indoor surfaces, including dining tables, work surfaces, and stairs, among others. Penetrates and protects against premature wear and damage. Contains 0.3-Liter. Includes one applicator and replaceable sponge.
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Bingham - Richmond
Your hotel has its own restaurant serving breakfast, lunch, dinner and brunch where you'll find a selection of items to try. Guests can also enjoy drinks as there is a bar/lounge. Guests can make use of the free WiFi.
Bingham - Richmond
Hotel Info: 1-877-214-4288from $133
- Superior Double Room, River View
- River Double Room
- Standard Double Room
- Standard Single Room
- Large Double Room
Also popular with travelers from the USA
At a glance
Key facts
Hotel size
- This hotel has 15 rooms
- This hotel is arranged over 3 floors
- Check-in time 3 PM-midnight
- Check-out time is 11 AM
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Pets not allowed
Extra people
- Roll-away beds available, charges may apply*
- Free WiFi in public areas
- Free WiFi in rooms
- Self parking *
Other information
- Smoke-free property
In the hotel
- Buffet breakfast daily (surcharge)
- Restaurant
- Bar/lounge
- Coffee shop/café
- Room service (during limited hours)
- Use of nearby fitness center (discount)
- Golfing nearby
- Kayaking nearby
- Meeting rooms 3
- 24-hour front desk
- Concierge services
- Tours/ticket assistance
- Dry cleaning/laundry service
- Laundry facilities
- Free newspapers in lobby
- Luggage storage
- Wedding services
- Multilingual staff
- Number of buildings/towers - 1
- Garden
- Terrace
- Fireplace in lobby
In the room
- In-room climate control (air conditioning)
- Air conditioning
- Minibar
- Coffee/tea maker
- Bathrobes
- Slippers
- Iron/ironing board
- Turndown service
- Private bathroom
- Jetted bathtub
- Rainfall showerhead
- Designer toiletries
- Hair dryer
- Satellite TV channels
- IPod docking station
- DVD player
- Video-game console
- Desk
- Free newspaper
- Free WiFi
- Phone
- Refrigerator
- Free bottled water
- Daily housekeeping
- In-room safe (laptop compatible)
- Connecting/adjoining rooms available
Special features
DiningBigham Restaurant - This fine-dining restaurant specializes in British cuisine and serves breakfast, brunch, lunch, and dinner. Guests can order drinks at the bar and enjoy alfresco dining (weather permitting). A children's menu is available.
Awards and affiliations
Green / Sustainable Property
This property participates in Green Tourism Program, a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.
Bingham - Richmond's small print
Also known as
- Bingham Hotel
- Bingham Hotel Richmond
- Bingham Richmond
- Bingham Hotel Richmond-Upon-Thames
Additional policies and fees may apply when booking more than 5 rooms. For more details, please contact the office using the information on the reservation confirmation received after booking.
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Optional extras
Self parking costs GBP 10 per night
Parking is available nearby and costs GBP 10 per 24 hours
Buffet breakfast is offered for an extra charge of GBP 12.50 for adults and GBP 12.50 for children (approximately)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


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Was our vacation to California relaxing? Not really. Was our vacation to California easy? No. Was going to the beach, zoo, desert, coast, shopping, dinner, pool, etc. easy? Definetely not, but, it was SO worth the trouble.
I'm a firm believer that taking kids out to dinner, on little day trips and on vacation makes them GOOD at going out to dinner, taking little day trips and going on vacation. There's a learning curve, of course, and infants are too young to know what's going on. I think they feel different vibes though. They see different things, smell different smells and see different people. Going out expands their little worlds.
Now that I'm done waxing philosophically — how the hell do we actually go, and do with one toddler who doesn't always want to go where I go, and two babies who can barely crawl. STROLLER. I freaked when I found out that I was gonna have three very little kids. I have to go out. I absolutely cannot be stuck at home. I'm awful at it. So the search for a legit stroller for 3 began. They don't exactly exist. BUT — I did find a double stroller with an awesome little thing called a Joey seat. It ain't cheap, but frankly, I didn't care.
So with the Joey seat, Lana feels really cool. She likes to say, "I'll lead the way", and I like to say, thank God I can push all my kids in one stroller. Joey seat comes off, and then it's just the Valco Baby Trimode Ex Twin. Quite the mouthfull.
There is no way in God's green earth that you can go anywhere with this dune buggy and go quietly into the night. Uh huh. We attract SO much attention with this stroller. Anything from "That thing is awesome" to "You poor woman". To the latter individual I say – well – I probably can't type it here. Anyway, that my twin mommy or three small kids mommy friends, is how we get wherever it is we're going. And we like to go, so we do! Be brave!! You can do it too. Here I am loading the bottom compartment with extra stuff at the San Diego Zoo.
Here are a few vacation pics to inspire you to just go! You can do it! So what if it's hard! Life isn't easy, but living it is the only way to go. So what if the kids cry. So what if they annoy some random mean person that you'll never see again. Take them out to see the world and to learn how
to live in it.
22 responses to "Getting Around With A Toddler And Infant Twins — HELP!"
looks like the ocean beach pier
Having seven kids in six and a half years I can totally relate. Our trips to the circus, beach and just playing outside and keeping track of everyone was exhausting. While they were growing up I must have counted to seven a billion times. It is a bit easier now since two are in college and five in high school. That brings another set of challenges. Sounds like you are on the right track enjoying them. These years will pass all too soon. Negative comments? You can only imagine, however, most people looked as us and would comment…'wish we had more children'. Maybe our paths will cross someday Munster. Keep lovin those babies!
You are amazing!! I'm definitely inspired.
My twin boys are only 10-weeks-old but we've gone out to dinner and brunch with them already. I also just ordered JJ Cole Bundle Me's to put in their double jogging stroller so I can take them out in the winter and not be stuck inside the next two months.
Our first real trip with the boys is in April though when we are flying to Florida.
Hey Megan, You and I have such the same philosophy about taking kids out into new places and letting them learn how to behave in new situations. Only thing is that my girls are now almost 25 and 30! It worked well for me then and looks like it does for you too! All I can tell you is that it does work and I'm so proud of the women my kids grew up to be. By the way, awesome stroller!
My family members every time say that I am wasting my time
here at web, but I know I am getting familiarity
all the time by reading thes pleasant articles.
This is going to be me soon. Where can I buy that stroller ???
I have been looking at this stroller! I just found out we are having twins and our daughter will be 2 when they are born. A stroller that I can actually maneuver is a must because I, too, cannot be stuck at home! But my question is, is your daughter comfortable in the seat out front and does she like it? My biggest fear is that my toddler will hate it, and without there being a tray for snacks/entertainment, I have my doubts…
Thank you!
How long/old was your oldest child able to sit in the Joey seat? My little boy will be almost 3 when the twins come along but I want a stroller to hold him too for big trips like the zoo & busy long walking events. He is small for his age but I am wondering if the Joey seat will work for very long. Thanks!
Hi, have you ever gone on a long haul flight with your kids, if so, were younallowed check in the valco stroller and joey seat?
Just wondering if you can use carseats with the stroller while the attachment is in use. I'm having twins and have a toddler.
Where did you find the special edition version to buy? I love that print, but can't seem to find it anywhere. I will have 3 under 26 months when my twins arrive. I am totally getting this stroller and the Joey seat.


text:
Goldman Sachs' Asian private equity unit has invested $110m in Indian cable distributor DEN Networks to fund its growth plans.
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2016 Schedule
Registration opens
September 1, 2015
Registration Deadline
January 15, 2016 by 1:00 p.m. (EST)
Electronic Submission Deadline
February 17, 2016 by 1:00 p.m. (EST)
Finalists Notification
March 4 , 2016
Finalist Presentations
March 31, 2016
The architectural engineering programs are encouraged to have the competing students present their projects to their peers and faculty. It is also encouraged that they receive comments and suggestions from these individuals at multiple instances throughout the preliminary design and design development stages of the project.
The judges will review the electronic submittals received and will select the finalist teams who will present in the competition finals.
All teams may continue to work on their projects after the electronic submission in anticipation of possible selection as a finalist team and in preparation for the finalist presentations. It is recommended that finalist teams present their projects to their faculty advisors and peers prior to the finalist presentations to the judges.
Final presentations will occur at the first AEI FORUM scheduled on March 31 to April 1, 2016 at Worcester Polytechnic Institute (WPI), Worcester, Massachusetts. The event will be broadcast by video to the public as well as all the architectural engineering programs and the winning entries will be published on the web.
The FORUM offers an opportunity for all members of the building industry, including structural, mechanical, electrical engineers, construction management professionals, architects, as well as students to discuss advanced strategies and state-of-the-art practices of building technology.


text:
This page is dedicated to the wonderful clients and pets that come into Beach Veterinary Clinic each day. If you'd like to include a photo of you and your pet on this page, please contact us!
Cocoa Coarsey (Yorkie Mix)
Deuce (Boxer)
Layla (Catahoula Leopard)
Lucy (English Mastiff)
Beach Veterinary Clinic,
4404 124th St. Ct. W, Cortez, Florida 34215 | Ph: (941)792-2838


text:
DeWalt™ 20-volt Cordless Hammer Drill Kit
This product is currently not available.
Item #: 09035562510
Online Availability: Out of stock
In-store availability - show
About this product
About this product
Product features
Product features
600-2000 rpm
- includes 2 batteries
- 30-minute quick charge
- reversible
- removable 20-volt lithium ion battery packs and case
- 3-year warranty
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Questions & answers


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#IoE Napkin Math and Your Daily CommutePerspectives
Google is creating a vehicle that drives itself. This isn't really news, right? They're testing it all over theRead More
EtherCloud Brings Global Ethernet ConnectivitySP360: Service Provider
We've talked about Ethernet Exchanges in the past – Why Should you Join an Ethernet Exchange and alsoRead More
Three Key Factors When Selecting an Ethernet ExchangeSP360: Service Provider
If you aren't familiar with the concept of an Ethernet exchange, it's a fairly simple one. AnRead More


text:
Click on a thumbnail to go to Google Books.
Agatha Raisin and the Terrible Tourist
by M. C. Beaton
No current Talk conversations about this book.
I had intended to read, "Murderous Marriage" before this, but didn't manage to get hold of a copy, so continued onwards to #6 in the series. In the end, it didn't matter, there's a 'catch up' at the start of the first chapter which pretty much covers all the books to date and, lets face it, they're not exactly complicated plots, so not difficult to catch up if you miss a book.
I seem to alternate between finding Agatha annoying & then warming to her... this time she was annoying. She seems to have turned into a tearful, clingy woman. Not the independent, pig headed Agatha I was used to. There was also too much about her love life and not enough sleuthing. Having said that, the redeeming feature was that she was in North Cyprus, staying in Kyrenia - exactly where I went on holiday last year & therefore I recognized all the places she visited & some of the hotels too.
All in all, a quick, easy read, not too taxing - perfect if you like the series.
You cant go wrong with a good Aggie
Agatha Raisin isn't a particularly nice person. Given the time period when this was written, I think the author was experimenting with a number of stereotypes by turning them backward. For example, Agatha loves James, but she spends loads of time with (& not surprisingly ends up sleeping with) Charles. If a male detective character did this in a novel in the late 80's to early 90's, it would be fairly normal, if he was the protagonist. If he was a love interest acting this way, then the reader would expect the (female) detective / protagonist to punish and/or drop him immediately. Neither happens to Agatha, although she is emotionally tangled up a lot.
The mysteries around this dynamic are pretty incidental. They are something for Agatha to run around finding out about so we can watch her be nosy & clever & not clever & embarrass herself & pretty much be Agatha Raisin, whom I can't seem to help liking in spite of her double standards & tendency to isolate herself with murder suspects & other silly behaviors. The murderer is usually just insane, which means the clues don't give us a logical puzzle to solve anyway.
I really liked this one. It was set in Northern Cypress, for the most part. It was a bit of a push with the overly-long Wikipedia type descriptions of things, like we used to do in college to increase the word count on thesis papers, but it was still enjoyable.
References to this work on external resources.
Wikipedia in English
Amazon.com Product Description (ISBN 0312965664, Mass Market Paperback)
Agatha Raisin's marriage was put off when her ex-husband showed up, unfortunately alive. Fortunately, he was murdered and Agatha solved the crime. Now she is off to Cyprus to track down her ex-fiance. Instead of enjoying their planned honeymoon, however, they witness the murder of an obnoxious tourist. Two sets of terrible tourists surround the unhappy couple, arousing Agatha's suspicions. And, much to James' chagrin, she won't rest until she finds the killer. Unfortunately, it seems the killer also won't rest until Agatha is out of the picture. Agatha is forced to track down the murderer, try to rekindle her romance with James, and fend off a suave baronet, all while coping with the fact that it's always bathing suit season in Cyprus.
(retrieved from Amazon Thu, 12 Mar 2015 17:57:48 -0400)
In her sixth delightful outing, Agatha travels north of Cyprus, only to contend with her estanged fiance', an egregious group of terrible tourists, and a string of murders as scorching as the Greek sun.
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Do you need a prison adventure? Get into your hardhat, slip into your overalls and pull on your boots and charge your headlamps before locking into the ladder system and descending 20 metres into the depths below.
Trek through sections of the labyrinth of tunnels on foot, then board the replica convict punts to explore the submerged passageways accessible only by boat.
Discover original blast holes, bores, oil lamp recesses and artefacts from the days when working in the tunnels was hard labour for prisoners.
Daily at 9.00am, 9.45am, 10.40am, 12.20pm, 1.40pm, 2.40pm and 3.25pm
Tour Length:
2 hours 30 minutes
Essential. Tickets must be pre-booked and pre-paidTo book tickets, please call 08 9336 9200 (we are not able to accept online or email bookings)Please have your Visa or MasterCard ready as full payment is required at the time of bookingOnce booked tickets are non-refundable and non-transferable
$60.00 per adult, $50.00 per concession, $40.00 per child (must be over the age of 12)
Wheelchair Accessibility:
This experience involves climbing down and back up a 20 metre ladder. It is not recommended for those with a fear of heights.
The tunnels are approximately 2 metres wide and as low as 1.5 metres high in some points. It is not recommended for people who suffer from claustrophobia.
The tour involves ladder climbing, walking while stooping (not crawling) and paddling small boats. You must advise your guide of any health issues that may affect your ability to complete this tour.
Want a sneak peek at the Tunnels Tour? Click here to view one minute snapshot video of what you can expect on your tour.
Download a Tunnels Tour Fact Sheet.


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Not to worry. Check out the archived thread of the Q&A with Ken Hutcheson, President of U.S. Lawns, and the LawnSite community in the Franchising forum .
Some Pics
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The Fraser Information Society is dedicated to community education on environment and development.
Community is dependent on its individuals and education performs a vital role in developing neighborhoods. Education offers humans having the ability to increase their lifestyle and performance by making well informed options and also by creating viewpoint on politics issues with regards to on their own. Developed nations around the world commit seriously on training since they realize the significance of providing education for their residents.
In these past few decades, it is obvious that our surroundings is suffering at our hands. Ecological activists all over the world are pleading with folks to prevent for a second and extremely have a look at what is happening. Not every person on the planet can focus all of their time and efforts into saving the environment, however. Luckily, it will not consider drastic adjustments in the manner that you simply live life to make a variation in the atmosphere. You will find methods to save environmental surroundings that do not require that you have more cash or maybe more time than you might have today. In reality, by simply following many of these easy steps, it can save you money.
Our hats are off to this window repair Lake Worth, FL company that understand the meaning of going green. Their core philosophy asks, "Why buy new when you can repair what you have?" We also think that looking out windows onto a natural setting is a great way to stay in touch with nature.
Moreover, there are numerous simple things that you can teach to your children to make aware of little thing that they can do to help saving our environment. Simple things like the following can really make a big difference:
- Turn the water off when scrubbing their teeth or washing their hands. Letting water operate continually is throwing away water plus it should also be rejected instead of switching this type of water on full great time.
- Turning the lights off when walking away from a room is yet another way they can help to improve the surroundings and spend less on your power expenses.
- Learn to sort cans, paper and plastics so that you can reuse. Also permit your young ones understand specifically how recycling will help the surroundings. We would eventually run out of resources to meet the supply if we didn't recycle.
- Don't stand using the fridge doorway open. Which not only wastes electrical power but it also allows the cool atmosphere to flee so the freezer should great by itself back, working more electrical energy.
We need to begin with the basics to make a good improvement. Meet up within your society, make use of the research trainer in school in order to start the you "save the Earth" project. After the kids work on preserving our planet, it offers them an upbeat attitude and raises on their own esteem. Children may have a beneficial influence on the atmosphere combined with the individuals and animals living for now and later on. Learning now will allow them to teach long term generations.


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Mike Anderson Chrysler Dodge Jeep Ram Supercenter of Logansport Sales Reviews
- 417 S 3rd St
- Logansport, IN 46947 (map)
- Chat with Dealer
Sales Reviews
Older Reviews (over 2 years old)
This dealer does not have any current reviews. The following reviews are over two years old - their ratings are not used to calculate the dealer's current aggregated ratings.
Recommend this dealer? Yes Purchased a vehicle from this dealer? Yes
I recently purchased a new car at Mike Anderson Chrysler Dodge in Logansport. I was a bit leary of the whole new car purchase as I would be doing it on my own this time and I was not only impressed with the inventory available, but with the sales staff. Very nice indeed. I found my salesperson to be...
Read the full review


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Europa Gatwick Hotel & Spa3
Balcombe Road, Maidenbower, Gatwick Airport, RH10 7ZR
Price FromView Rooms
"There was no decaffeinated coffee at all to use in rooms - most disappointing. The room had a nightlight, thereby guaranteeing poor sleep, h..."
"The staff were very helpful on arrival, but the place is quite shabby and in need of a make-over. There is a serious problem with parking, a..."
About the hotel
This pretty hotel with Spanish and Mediterranean architecture offers comfort, value and first class facilities. The fabulous courtyard with a fountain and landscaped gardens are the perfect place to sit and relax and is only 10 minutes' drive from Gatwick Airport. Free Wi-Fi in public areas, and private on-site parking can be arranged.
All 211 traditionally styled bedrooms offer a TV, tea and coffee facilities and a private bathroom. Gatwick Europa Hotel has free Wi-Fi in public areas, and private on-site parking can be arranged. You can relax in our indoor heated swimming pool or take it easy in our sauna facility and there is a fully equipped gym you can use to work out in.
The Rafters bar is cosy, with a feature fireplace and houses a modern snack menu, and leads out onto the Courtyard. The warm and inviting reception is spacious and has a mezzanine floor where the restaurant is situated. The Mediterranean restaurant offers a fantastic menu and caters for all cuisines. It is very spacious and overlooks the bright and airy reception area from a mezzanine floor.
There is a Health and Leisure club where you can make the most of your stay, per session £4. 00 for an adult and £2. 00 for a child. The 13 Conference rooms have first class facilities and can hold up to 132 people. Free Wi-Fi in public areas, available in every room, 2 x 20 minute complimentary sessions per day, unlimited access £7 per 24 hours.
Transfers to the Airport are provided by taxi and cost approx. £9. 00 each way. Please contact hotel for details. Dogs are welcome, terms and conditions apply including a £50 deposit. Contact the hotel for more information.
Read MoreLess
Facilities Show/hide
- Main
- Disabled Facilities, 24 Hour Reception, Cots available, Smoking allowed in bedrooms, Tea/Coffee making facilities in each room, Hairdryer in each room, Trouser press in each room, Telephone In Each Room, 24 Hour Room Service, Limited room service for hot food, Wake Up Call Available, Pets Allowed, Ground floor bedrooms, Lift to all floors
- Parking
- Car parking available onsite
- Business
- Wi-Fi Available, Meeting Facilities, Wi-Fi Available In Public Areas, Wi-Fi Available In Rooms, Private dining services
- Dining
- Restaurant, Bar
- Leisure
- Gymnasium, Indoor Pool, Fitness Centre, Sauna, Steam Rooms, Solarium, Jacuzzi
- In Room Entertainment
- TV, Radio
- Accessibility
- Disabled Access Public Areas, Disabled Access Bedrooms, Disabled toilets on ground floor, Wheelchair Access, Wheelchair Access To Conference Rooms
Can't find the facilities you're looking for?
- Call us on 0333 300 1007 and we'll help find the perfect hotel for you
- Call
Useful Info Show/hide
- From 14:00 hours
- By 11:00 hours
- Up to 8 years old
- 01/03/2010 to 01/03/2020 - Important Information: The hotel will charge a £2 administration fee on all credit card transactions. Guest are required to show photo identification and valid credit card upon check-in. The price shown is based on the occupancy and dates you have searched for. Prices and availability are subject to change based on the arrival date, number of nights and occupancy searched for. All prices are inclusive of all local taxes.
- Pets are allowed
Customer Reviews
Our reviews are from genuine LateRooms.com customers. We verify that the customer has stayed before leaving a review.
37% would recommend it to a friend
Customer service
Food quality
Room quality
Dirty room, very poor customer service, rude staff member at the reception desk, incompetent manager
I've stayed at the hotel from Thursday to Sunday.
When I arrived my room was dirty, hair on the dirty bedsheet, condom on the floor, dirty bathroom. I've reported that to reception desk immediately. Staff member at the reception that night (01/09) had good customer service. My room has been swapped. New room was much more cleaner except that I have noticed dirty bathroom, hair in the bath tub etc but it was too late at night to pack again and ask for different room. Day 2, room has not been clean it was around upmarket when I got back from business meeting called reception several times - no answer. Went to talk with staff member at the reception and found him very rude and ignorant about dirty bathroom issue. He advised me that they will send someone to clean it and manager will give me call back. Staff member who came to clean showed up with wood polisher spray so I explained him that bathroom needs too be cleaned rather than furniture. Came again this time with air freshner mixed explaining that was all he could find. Went to speak to reception desk again, explaining that it should be antibacterial cleaning product rather than wood polisher etc. 3 hours later around 9pm manager called me asking what's wrong and explaining that it was misscomunication he also offered me a free breakfast. I didnt accept it. Next day room has been cleaned. 1. I'm not happy that I've been waiting 2 days for My room to be cleaned. 2. I don't think that offering free breakfast in this situation is appropriate, someone should come and sort out problem first even if its manager himself, rather then : "there is nothing we can do at this moment, someone will clean tomorrow, do you want a free breakfast?". 3. I'm not happy with miserable, rude, ignorant manager and receptionist. 4. I feel that my health and well-being has been put at risk by staying at your horrible hotel. 5. Even if you would let stay for free it wouldn't justify condition of this room and I do think it's health and safety issue. Also, I took some pictures if anyone would like to see them. Absolutely nightmare !
Read More Less
Shabby rooms
The room was a cheap room but I still expected a reasonable standard.
For such a big and busy hotel (Gatwick airport customers mainly) the room was terrible, tired, dirty and old. The toilet even had the stains from the previous guest!. I will not be staying there again even at £47/night.
Read More Less


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realmagick.com The shrine of knowledge.
A selection of articles related to travel.
Original articles from our library related to the Travel. See Table of Contents for further available material (downloadable resources) on Travel.
- A Treatise on Astral Projection, Part 4: More Rope Techniques
- ROPE is a very effective projection technique, but it still has to be learned to be effective. I would like to elaborate on a couple of points about the technique, inspired by the feedback I have received so far. There is NO visualization required - AT ALL -...
Parapsychology >> Astral Projection
- Spider: Grandmother of Creation
- At the dawn of summer, in the warmth of springtime, Spider peeks her head out and begins again to spin her tale. Her tale, like her web is spiral, each year bringing greater more elaborate worlds and possibilities into manifestation. Her story, her web is the...
Symbology >> Animals
- Harding, Deborah
- Deborah Harding began gardening alongside her parents when she was just able to walk. She lives in Ohio with her husband and two daughters. She writes articles on herbal concerns for magazines and web-zines, and gives lectures and workshops on growing herbs...
Real Interviews >> Authors
- Raidho
- Raidho, the "r-rune", is the fifth rune of the first aett of the Elder Futhark. The Old English Rune Poem, Old Norse Rune Rhyme and Old Icelandic Rune Poem all refer to horses in their verses on Raidho. Horses are how people got around back then,...
Divination >> Rune Stones
- Survivalists' Guide for the New Millennium: Chapter 5
- WHERE I LAY MY HEAD IS HOME A foot and light-hearted I take to the open road, Healthy, free, and the world before me, The long brown path before me leading Wherever I choose. Henceforth I ask not for good fortune, I myself am good fortune, Henceforth I...
Philosophy >> Survivalists Guide for the New Millennium
- You May Be Using Sunlight in Your Magic (And Not Even Know It!)
- A Circle is cast between the worlds. This space is filled by gentle candle light, and filled with the scent of fragrant herbs. Energy is raised, focused with purpose and then released with a sudden "whoosh." While there are many types of energy used...
Paganism & Wicca >> Spells
- Of Master and Discipline
- Part 1 | Part 2 | Part 3 | Part 4 | Part 5 | Commentary Part 1 The following is a fictional account of a spiritual awakening with a factual basis. This five part series is offered to promote and encourage the practices of the World Mind Society, making the...
Mind >> World Mind
Travel is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Travel books and related discussion.
Suggested News Resources
- How Gwyneth Paltrow Likes to Travel
- But it's also where she shares her passion for travel and writes about finds from her trips. In fact, chances are high that most sightings of Ms. Paltrow, 43, these days are of when she is on the road.
- Former Katherine travel agent pleads guilty to defrauding NT Government of $40k
- A Katherine woman who ran her own travel agency has pleaded guilty to defrauding the NT Government of about $40,000, with the court hearing she learnt the practice of inflating invoices when she worked for another business.
- Pentagon investigation reveals $458 million in botched travel payments
- The Pentagon is promising to expand its crackdown on improper travel payments after an internal investigation found widespread errors in vouchers that troops submit for reimbursement, according to a new report. The Defense Department Inspector General ...
- Tourist Security Is an Unspoken Theme for Travel Operators at ITB Trade Fair
- Security fears are on everybody's lips at the ITB travel trade fair in Berlin this year as a battered tourist industry seeks to reassure travelers and tour operators that they need not shy away from booking summer holidays for this year.
- Robots shake up check-in at Berlin travel fair
- Her life-like facial movements may be scary to some, but according to some industry experts, Chihira and robots like her, might just transform the travel industry. This is Mario. Mario is also showing off his people skills at the convention.
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
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Please use this identifier to cite or link to this item:
|Determination of Glucosamine by Ultra-high Pressure LC in Shrimp By-Products
|Sanches-Silva, A.
Ribeiro, T.
Albuquerque, T.G.
Paseiro, P.
Sendón, R.
López-Cervantes, J.
Sánchez-Machado, D.I.
Soto Valdez, H.
Angulo, I.
Aurrekoetxea, G.P.
Costa, H.S.
|Segurança Alimentar
|Issue Date:
|Instituto Nacional de Saúde Doutor Ricardo Jorge, IP
|Glucosamine is one of the most abundant monosacharides and is part of the structure of the chitosan and chitin, which compose the exoskeletons of crustaceans, other arthropods and the fungi cell walls. Shrimp by-products are a good source of glucosamine because about 45% of the animal is composed of inedible cephalothorax and exoskeleton. The project 'Preparation of active packaging with antioxidant and antimicrobial activity based on astaxanthin and chitosan' aims to develop a methodology for the incorporation of compounds obtained from shrimp waste in plastic matrices for the development of an active packaging with antimicrobial and antioxidant properties. In the frame of this project, shrimp by-products were fermented and insoluble chitin was purified by a sequence of steps: depigmentation, deproteinization, demineralization and blanching. The aim of the present work was to optimize a method to determine glucosamine by Ultra-high Pressure Liquid chromatography (Ultra Performance Liquid Chromatography, UPLC) with diode array detection (DAD) from shrimp by-products. First, an acid hydrolysis of the chitin of shrimp by-products is carried out. Afterwards, a derivatization is done because glucosamine does not contain a chromophore. The selected derivatization reagent was 9-fluorenylmethyl-chloroformate (Fmoc-Cl). The chromatographic separation is achieved using a vanguard pre-column (Acquity UPLCÒ HSS T3, 1.8 µm particle size) and a column (Acquity UPLCÒ HSS T3, 2.1 x 50 mm, 1.7 µm particle size) at 38 °C. Quantification of glucosamine was carried out at 265 nm. The mobile phase is a gradient of phase A [water (pH 6.5)/ methanol, 85:15 (v/v)] and phase B (acetonitrile) with a flow rate of 0.3 mL/min. The optimized UPLC method allows an excellent separation in just 10 min of the two anomers of glucosamine, of the Fmoc-Cl and of its corresponding alcohol, which is the hydrolysis product of the spontaneous reaction between Fmoc-Cl with water. Several samples have been analysed, some are commercial samples (chitosan with low molecular weight; chitosan with medium molecular weight; chitosan from shrimp shells; chitosan from crab shells), and three other samples produced from shrimp by-products in the frame of the project. Commercial samples presented a higher amount of glucosamine content than in-house produced samples.
|Peer review:
|Appears in Collections:
|DAN - Posters/abstracts em congressos internacionais
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|View/Open Request a copy
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Bartoni Longford Chino for Men in Stone
Bortoni Longford Chinos for Men in Stone. These comfort stretch trousers features a plain front, side pockets and back pockets with button fastenings, and comes complete with a stretch belt.
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For any further information please visit our Returns page.
Any Questions? - Either contact us via email firstname.lastname@example.com, or telephone us on 01473 256061 between 9 am - 6 pm Tuesday to Saturday


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|Prev Close
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These five stocks look ready to break out of weekly consolidation patterns. Here's how to trade them from here.
The natural gas operator installed two new directors, including the former CEO of Occidental Petroleum, as Keith Meister calls off a change-of-control proxy fight
Cramer says Bluebird Bio is too speculative for him but he likes Enterprise Products Partners.
The market is fearful. Use that fear to buy, Cramer says.
Enterprise Products Partners L.P.
Credit Suisse upped Enterprise Products (EPD) stock rating to 'outperform,' citing the company's solid risk/reward proposition.
Cramer says Xerox' and Alcoa's parts are worth more than the whole.
Apple stock has jumped 21% since May when Cramer said buy at $93. Did you listen?
The activist's move comes as he ramps up a change-of-control proxy contest in the wake of Enterprise Products withdrawing interest in a combination.
Enterprise Products Partners has withdrawn its takeover bid for Williams Cos. after submitting a second offer in late August and Jim Cramer wants to hear from management.
U.S. stocks sold off as the chances of a September rate hike nearly doubled amid hawkish Fed commentary.
Stocks add to losses on Friday morning as crude oil backs off from a major rally a day earlier and the chances of a September rate hike increase.
Stock futures move lower on Friday morning as crude oil backed off from a major rally a day earlier that pushed prices to close at a two-week high.
Enterprise Products Partners L.P.
Enterprise Products Partners L.P.
The new directors all have experience leading large publicly traded companies, which Corvex Management had criticized Williams for lacking.
The nominees will serve as placeholders until the activist hedge fund identifies actual candidates for the proxy contest, which Williams criticized as distracting and costly.
The pipeline operator called the move unfortunate, distracting and costly, as it's moving forward with its own plan to identify qualified and independent directors.
The S&P 500 closed just points from its record high as a crude oil rally distracted Wall Street from uncertainty over the Federal Reserve's rate-hike plans.
Not too long ago, it was best to stay from foreign assets and energy exposure. That was then, this is now.
Enterprise Products Partners L.P.
Enterprise Products Partners L.P.
Trade-Ideas LLC identified Enterprise Products Partners (EPD) as a "water-logged and getting wetter" (weak stocks crossing below support with today's range greater than 200%) candidate
Any weakness is an opportunity to revisit the sector but with greater emphasis on stock-specific opportunities and dislocations, one analyst says.


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This cake was made for a baby shower. This was my very first experience with molding and shaping animals. Needs more work but for the most part I was pleased. All fondant except for the green swirls which are buttercream.
CakeCentral.com is the world's largest cake community for cake decorating professionals and enthusiasts.
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Watch Manny Episode 15 Online Free
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Of the high-rolling top 'hot celebrities' of the wealthy upper class in Korea's high society, Kang Hye Na (Hena) is the one desired by the men, feared and hated by the women. Being the only successor to the largest conglomerate company, Kang-san Group, Kang Hena has both the looks and the background. She is the owner of the 'Lady Castle' and lives a 'princess-like' life with her servants.Until one day, out of pu......
Park Yong Ha portrays man who once had it all. A scam ruined his family and his father's company went bankrupt because of him. He wants revenge against those who made his life a living hell. Park Si Yeon is his girlfriend who works diligently in order to help him repay his debts.......
This drama commemorates the soldiers who gave their lives in the Korean War, fought between North and South Korea between 1950 and 1953, and is designed to remind people that the heavy cost of human lives far outweigh any national glory. Lee Hyun Joong is a South Korean squad commander and war veteran who is dedicated to protecting the lives of the soldiers serving under him, despite his jaded outlook. His chance meetin......
The drama about a man trying to achieve what is thought to be impossible: fulfilling his dreams of being a great soccer player. Cha Bong Gun, a soccer player with great potential, wants to become a member of the national soccer team. As he works towards his goal, he meets Kang Hae Bin, an attractive and independent rookie sports agent who ends up bickering with him all the time. With Jang Seung Woo, an elite attorney, ......
Based on the events occurring around "Route 1", which lies between Seoul and Pyongyang. The story about Officer Lee Jang Woo who finds himself in a war that he is not prepared for in order to protect Soo Yeon, the woman he has known and loved since youth. However, he is able to put it past him and he displays extraordinary survival skills, friendship, cooperation and ideology under brutal war conditions. Soo Yeon aw......
This drama is about a prince is forced to live as a commoner and uses his gambling skills to take revenge on the King.
Baek Dae Gil (Jang Geun Suk) is the best gambler in the Joseon era. He holds deep resentment inside, but is also cool on the exterior. King Yeongjo (Yeo Jin Goo) is a man who never lower his head without a convincing reason. Meanwhile, Dam Seo (Im Ji Yun) exists solely to take revenge upo......


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Vikings Kicker To Meet Empathetic Letter-Writing 1st-GradersMinnesota Vikings kicker Blair Walsh plans to visit the first-graders who sent him letters and drawings of support after he was lambasted by fans for missing a field goal that could have given his team a win in Sunday's playoff game.
Vikings Blow Fourth Quarter Lead, Miss Field Goal In Loss To SeahawksThe Minnesota Vikings outplayed the Seattle Seahawks for three quarters. But, it only took three plays for the Vikings lose 10-9 Sunday at TCF Bank Stadium.
Minnesota Vikings Head Into The Offseason Optimistic, But UnsatisfiedThe Minnesota Vikings have more confidence and optimism heading into this offseason than they did a year ago. They have two of the most important pieces in place in head coach Mike Zimmer and Teddy Bridgewater. Also, they improved in several areas from the past season. The Vikings have 12 free agents this offseason, but just one opening day starter.
Fantasy Football: Top 12 Kickers To DraftHere's the deal with kickers. You're not drafting one until the last round. Here's our top 12 kickers to draft.


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Introducing Indigo Dreams, the newest collection from Rae Dunn. Inspired by her travels, deep blues meet signature artisan style in this eclectic collection. Only from Magenta.
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A Pennsylvania news team went to film a report on an alleged "haunted" house and they got much more than they bargained for because they claim they were attacked by a ghost. The home is located in Hanover, Pennsylvania, and was featured on a national television show The Dead Files which aired on the Travel Channel on Saturday night. This was because the homeowners stated that the house was extremely haunted, with numerous ghosts and various other entities.
1.Look very closely at photographs from the haunted location for anomalies that might be caught on film.
2. Unexplained shadows in or around the dwelling.
3. Excessive noise such as creaking, growling, faint voices and/or tapping
4. Objects moved from one place to another or misplaced objects
5. Flashes of light or orbs in your sight
6. Wavy distortions in the air.
7. Cold air in areas where it is unexplained
8. Electronics unexplainably shutting off and on
9. Watch for your pets growling and looking at something that is not there. Animals are very sensitive to Spirit.
10. Unusual unexplained smells, such as tobacco, flowers, perfume's.
Simply confirm your registered email address below and click "Reset Password." We will immediately email you a link back to the site where you can enter a new password for this account.
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Game Credits
|Afterfall: InSanity - Extended Edition (2012)
|(Level Designers)
|Afterfall: InSanity (2011)
|(Level Designer)
|Dying Light (2015)
|(Level Artists)
|Gears of War: Judgment (2013)
|(Sr. Environment Artists)
|Sniper: Ghost Warrior 2 (2013)
|(Level Artists)
Developer Biography
There is no biography on file for this developer.
If you have a portrait of this person, you can upload it to the MobyGames database.
Related Sites
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text:
iHerb Customer Reviews
Savings of: $1.20 (20% off)
great on everything
Posted by suemio96 on Feb 04, 2015
I use it on potato, corn etc be it in baking or frying the veggies.
Not bad!
Posted by Reviewer3312905 on Aug 06, 2011
I know it's got some quality stuff in it, I would have tried to add some other vegetables or herbs to make it less "overpowering". (or taken some out of it)
Love it!
Posted by erikamarija on Aug 21, 2012
It is fantastic! U don't need to add salt, just use this!
Great spice
Posted by Reviewer1877965 on Jun 17, 2012
It's really All-Purpose seasoning. I use in soup, with a potato, rice... is suitable for everything, helps to correct taste if something it not tasty enough. And i love Simply Organic bottles (under the metal lid there is plastic lid with holes), they are reusable.
Posted by Reviewer3347694 on May 24, 2011
Aromatic, organic and easy to use. Good product
Posted by Reviewer2309605 on Jun 28, 2011
Seasons my food nicely. Very happy
Posted by Reviewer1213449 on Aug 18, 2011
like it.
Posted by Reviewer2095440 on Dec 14, 2011
very good
Posted by Reviewer1470632 on Dec 15, 2011
like it very much, and thinking of ordering more, rich flavor!
Perfect for oven roasted veggies
Posted by kaheekim on Sep 18, 2012
It takes plain roasted broccoli or cauliflower and makes it taste so professional!!


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3 Cashier Jobs in Vanderbijlpark
1-3 of 3 Jobs
Ubusha Recruitment (Pty) Ltd - Vanderbijlpark, Gauteng
Our client is seeking a Receptionist / Cashier in their Motor Vehicles division in Vanderbijlpark. In this busy and varied role, you will be responsible for...from: Careers24 - 19 days ago
Vanderbijlpark, Gauteng
• Std 10/ Gr 12; • 2/3 years experience in field; • Computer Literate including Pastel / OMNI Accounts; • Fluent in Afrikaans & English (Read & Write) •...from: Gumtree ZA - 20 days ago
Sasolburg, Free State
Pizza Boss Vaalpark is Looking for a young Female Cashier fluent in Afrikaans and English. 45 hour work week, with 1 weekend on and 1 weekend off shift rotation...from: Gumtree ZA - 8 days ago
jobs by