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I think Enter the Dragon is the best martial-arts movie ever. What's your favorite martial arts movie?
I like it a lot but I don't know if it's my favourite. Hears voices in his head...probably due to his headphones.
legend of the drunken master with jackie chan "You know what you have to admire? A Catholic hit man who blesses himself just before he strangles someone."-George Carlin "Vaya con Dios" -Monsignor Martinez
This was an awesome movie, apparently theres a sequel.
with Jet Lee I don't remember one but he fightsgood and he is not pussy
Jet Li is my favorite action star; I love all of his movies expecially "The One" and "Kiss Of The Dragon"
How could I forget?! Those are cool too!! Hears voices in his head...probably due to his headphones.
I loved the part where Jet Li Kicked a pool ball out of the pocket of the table and then at the guy's head who was shooting two big guns at him. What was your favorite part of the movie?
Any one?"I love anime and manga! Also J-Rock!"
Bruce lee's "Chinese connection," was good. Another good samurai movie that little have seen is "Heaven and Earth" CHACHE5150
rush hour 1, 2, and 3 were very funny
just becaeuse i'm a girl doesn't mean i can't like guy shows!!
One of my favorites is "Iron Monkey," gr8 fight scenes..I Think Im Being Watched... You cant trust anyone, not even Sesame Street....=D
is one of them
Need to look at the last couple posts..I Think Im Being Watched... You cant trust anyone, not even Sesame Street....=D
let's take back our symbol
I like Jackie chans old movies, All Bruce Lee movies and Martial Arts Movies where I have no idea who the actors are are.
all jet li movies,movies wit jackie chan nd jet li,the karate kid movies.
life is rough.so dont take it lightly.
fantasy mission force. "I WANT YOU TO THROW ME AWAY!!!"
I love martial arts movies expecialy (IP man) with Donnie yen if you havent seen it, you are trully missing out, Its one of the greatest martial arts movies ive ever seen ever period.
for real check it out
Enter the dragon
This is a marvelous movie. I like this movie a lot.
< =D =) =. :D :) :. =P =f =B =b =O =X XD >D 8D 8) =5 =E =H :P :B X) >) 0) -) -D 0D o_O >
ive always bin a huge fan of the matrix trillogy the martial arts was very uniqe it was the spark of martial arts for me(Bite my shiny metal a**)
If you can find a movie called "Ong Bak", you will be in for a treat!!!!
One sword to rule them all.....................
Been watching martial arts films for at least a few months now, in terms of intensive viewing.
Some of my favorite titles? Dance of the Drunken Mantis,
Enter the Dragon,
The One-Armed Swordsman vs. The 9 Killers,
Last Hurrah For Chivalry,
Hero (Jet Li),
Crouching Tiger, Hidden Dragon,
Black Mask,
The Contract Killer,
I watch them mostly for the fight moves and choreography. Yuen Wo-Ping is my favorite choreographer.
This is a pretty cool movie. I have watched this movie with my friends and spent a lot of time with fun and humor.


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Except where noted, MP3's are available at 320 kbps -- plays on iPod® and all MP3 players
Item Description
Legendary British folk-rock alchemists Fairport Convention return to the scene with "Over the Next Hill", their first new studio album since 2002's acclaimed anniversary celebration XXXV. Recorded after nearly three years of constant touring through the US and UK, Over the Next Hill finds the longtime Fairport lineup of Simon Nicol (guitar/vocals), Dave Pegg (bass/vocals), Chris Leslie (mandolin/fiddle/vocals), Ric Sanders (fiddle), and Gerry Conway (drums) scaling new heights of spry ensemble interplay and rich vocal choruses.
Customers who purchased Over the Next Hill also purchased:

subset: commoncrawl


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Quality Education in the Benedictine Tradition
April 19, 2013
Saint Vincent College Small Business Development Center will host a seminar, Computer Security Issues, on Thursday, April 25, from 9 a.m. to noon. Participants will learn to protect their computer, information and identity. This seminar will inform attendees on the newest threats to computer security and discuss the latest information on firewalls, antispyware, anti-spam and other programs that can be used to keep information safe. The fee to attend is $40. Coffee/tea set up and light refreshments are included as well as an optional one-year subscription (12 issues) to Inc. magazine, valued at $10. Joe Polk, technology specialist consultant, will present. Polk was previously senior technical specialist with PennTAP, web technology specialist with Marconi PLC and web developer with Management Science Associates in Pittsburgh. Saint Vincent College Small Business Development Center is part of a statewide system of university-based economic development organizations, whose mission is to provide high quality education and consulting to entrepreneurs, to help them start and grow their businesses in the competitive global economy. Early registration is recommended, as space is limited. To register or to obtain additional information on the program, contact the Saint Vincent College SBDC at 724-537-4572.
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The South Carolina Stingrays have resigned forwards Andrew Cherniwchan and Eric Alexander for the 2013-14 season.
Cherniwchan, 24, completed his first full professional season last year with the Stingrays recording 11 goals and 14 assists for 25 points in 50 games and was tied for the team lead with 103 penalty minutes. In four Kelly Cup Playoff contests, the Hinton, Alberta, native added one goal.
"We are looking forward to having Andrew back for his second season in South Carolina," said said Stingrays head coach Spencer Carbery. "He played a large role on our team last season, playing in all situations throughout the year. He had a solid rookie season and we expect that he will continue to progress and have an even bigger impact this year."
After completing a four-year collegiate career at Northern Michigan University, Cherniwchan joined the Stingrays late in the 2011-12 season recording three goals in five regular-season games and three points (two goals, one assist) in eight playoff games.
Alexander, 23, made his professional debut with the Stingrays late last season after wrapping up his senior year at Ferris State University. In his first ECHL game, Alexander had three assists and added his first professional goal in the final game of the regular season a night later.
"Eric was a player we targeted late last season out of college, who stepped right in and produced immediately," Carbery said. "He has good offensive instincts, a large frame that plays physical and has a willingness to go to the high-traffic areas of the ice. Last year's experience should put Eric ahead of the curve and enable him to step right in and contribute next season."
Through four seasons at Ferris State, Alexander totaled 47 points (19 goals, 28 assists) in 124 contests. In the summer of 2011, he attended the Washington Capitals (NHL) Rookie Development Camp in Arlington, Virginia.


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Convert your Lifefactory glass baby bottles to grow with your child!
Lifefactory Sippy Caps are leak resistant, and have a steady flow control, making them great for toddlers! Quickly converts a 4oz or 9oz Lifefactory Glass Baby Bottle into a sippy cup, as your child grows.
BPA Free. Dishwasher safe.
Includes (1) Raspberry & (1) Royal Purple Sippy Cap. (Also available in Green/Blue)
Made responsibly in China.


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Top Definition
The proper spelling of fairy. Everyone has their own faerie and daemon. Especially useful in magick if you're a Witch or Wiccan.
"I have a faerie called Feather Hailwitch"
door evilfaeriequeen 13 maart 2004
Trending Now
Can you define these popular missing words?
The most beautiful girl in the world. There is only one.
Josie, you are my faerie.
door ImAFaerieToo! 1 oktober 2011
Faeries are earth spirits. They live among each element completely hidden. They have cousins called Pixies. Pixies however, are very mischevious. They enjoy tormenting other creatures for fun. Little pranksters.. I hope you never meet one. Pixies have a bad reputation for finding a creature and clinging to them until death. Faeries can be somewhat close to a Pixie, but mostly they are loving, playful, and carry with them a child-like enthusiasm for life. Hide among the pedals of a Daisy, you are a Faerie.
I have a faerie, but I shan't find it yet.
door xbloody_Niñax 23 december 2006
Faerie noun.
Any of a number of Celtic spirits.
Any of a number of Celtic spirits.
I saw a Faerie last night. It ate my cat.
door Corey s. 16 december 2005
My friend Ryan is such a faerie that he has sex with men frequently.
door KFCConspiracy 26 september 2006


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Source: The Detroit News
quote: You list some very nice vehicles, but for someone like me who currently would be stretched financially to purchase a vehicle costing $25,000 it would be difficult to afford the more expensive fuel or to purchase a more expensive fuel efficient vehicle.
quote: but how does that help people who are struggling financially?
quote: For me to save money with fuel savings by purchasing a new EV like a Nissan Leaf, gasoline will need to cost about $35-$40 per gallon.
quote: But as there is a hole market for small cars here in Europe and most of the world, there is none in the the US, as you dont even can get the Aygo in the US.
quote: I have brother in Texas, ware i come every 2~3 years, and still every time, i come there, i am amazed how big the cars are compared to Europe.
quote: Jealous :P
quote: Why does the common person need a massive car?
quote: People drive smaller cars in Europe because when presented with the choice between big cars and smaller cars, some choose smaller cars. This makes more economic sense for them, as smaller cars consume less fuel and are therefore cheaper to run.
quote: And when you up the prices 10% a year, at the time you need one, you can get one secondhand.
quote: I also wonder if an Aygo or Think City EV can get me 20 miles to work when there is 8 inches of snow on the road.
quote: And own a 6L V12 Jaguar, and a 500hp Skyline that i would love to drive daily . But instead i drive now daily a Think City EV, and have a 2006 GS450h for long trips. But will get in 6 months a "Tesla Model S Performance" that i ordered. Why the Model S, because even do me and my wife got well paid jobs, i don't wane waist it on fuel that cost $10 a gallon.
quote: What other choices should the Govt restrict, or penalize, in your world ? Size of the house ? Size of the HDTV ?
quote: In a world ware my government looks out for my, and the generations behind me best interest in the long run.
quote: In a world ware my government looks out for my, and the generations behind me best interest in the long run.
quote: As for other things like size of houses, thats up to the market, but even there are building regulations, like minimum isolation is a normal thing i would say.
quote: I find it hard to believe you're that naive but there you have it.
quote: Do you really believe it's the Govt's job to tell you what's best ?
quote: But why shouldn't the Govt limit the size ?
quote: why can't ... shouldn't the same logic apply to housing ?
quote: Or size TV ?
quote: FWIW I think Govt should stop incentivizing people to have children. Instead of giving people a tax deduction for each child, they should be handing out a tax increase. But that's a whole different (though related) post.
quote: The only difference is when it happens.
quote: And the growing population and rise of the middle classes of China and India and others will so far outpace the oil savings such efficiency efforts bring forth that you're kidding yourself if you think that having everyone driving an Aygo (or Scion IQ here in the US) will make a difference of more than a few years.
quote: Take heart though, the technology to make fuel exists. When the price of oil gets high enough (actually stays high for long enough) that technology will be economically viable. Pilot plants have opened and idled with the rising and falling oil prices. IIRC sustained oil prices over $120/BBL are the estimated breakeven point.
quote: ps. I live in Norway, have a almost twice average income, my wive makes reasonable close to what i get, we can afford to drive a new gas guzzler car, if we want to, we just hate to trow away money on transportation.


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Dr. James Noel (SFTS), "Black Religion in the Atlantic World During the Age of Revolution: Excavating the 'Sublime'"
The May 10 ceremonies at Pacific Lutheran Theological Seminary's Chapel of the Cross recognized 62 graduates who completed their degrees in Fall 2011 or Spring 2012. Thirty-six students graduated with a Master of Arts degree, five received a Master of Arts with a concentration in Biblical Languages, and twenty-one received the Doctor of Philosophy degree.
Kang Hack Lee, Christian Spiritual Direction for a Confucian Culture: A Korean Perspective
Jung Eun Sophia Park, A Hermeneutics of Dislocation as Experience: A Resource for Asian American Spirituality
Julia D.E. Prinz, "Self-Implicating Biblical Spirituality": Johann Baptist Metz and Dorothee Sölle at the Interface of Biblical Hermeneutics and Christian Spirituality
Franciscan School of TheologyAssistant Professor of Pastoral Theology
At GTU since 1995
Jesuit School of Theology of Santa Clara UniversityAssociate Professor of Social Ethics
Core Doctoral Faculty Member
At GTU since 1988
Jesuit School of Theology at Santa Clara UniversityAdjunct Associate Professor of Liturgical Studies
Core Doctoral Faculty Member
At GTU since 1996
PhD, Graduate Theological Union, 1996
MA, University of Notre Dame, 1980
MA, LaSalle University, 1974
BMus, Manhattanville College, 1965
At GTU since 2008
STD, University of Fribourg, Switzerland, 2008
MA in Theology, Graduate Theological Union, 2000
MDiv, Dominican School of Philosophy and Theology, 2000
Dominican School of Philosophy and TheologyProfessor of Theology
At GTU since 1985
At GTU since 2007
PhD, Graduate Theological Union, 2011
MDiv, Lutheran Theological Seminary at Philadelphia, 2003
BA, Eastern University, 1991
At GTU since 2010
PhD, Graduate Theological Union, 1991
MDiv, Princeton Theological Seminary
BA, University of Oregon
Phone: 510/204-0733
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I've been tagged by Carrie at the Natural Moms Talk Radio blog to do the 7 Burning Questions Meme:
1. If you could have an endless supply of any food, what would it be and why?
I'd probably pick pad Thai with cucumber salad. I could eat that for every meal for the rest of my life! Chips and quacamole comes in close second!
2. If you were an animal what would you be and why?
I don't know! I guess I am really glad I am not an animal. But if I were a cat that was treated like a human and served really yummy food, that wouldn't be so bad.
3. If you could only describe yourself using three words, what three words would you use?
confident, feisty, & sincere
4. If you could be a super hero who would you be and why?
I secretly wouldn't mind a bit of Sydney Bristow from Alias mixed with WonderWoman. Would be cool to fly. And kick butt.
5. What is the most embarrassing thing that has happened to you?
The one that sticks out in my mind the most is the movie theatre incident and also during my wedding vows when I said I DO! really, really, really LOUD.
6. What is one of your biggest pet peeves and why?
Email forwards. Especially the ones that say you must pass this on to seven people within 3 minutes or you don't really love Jesus. Do I actually need to explain why on this one?
7. Out of red, green, blue, yellow and orange which one is your favorite color?
If you chose red what is one of your favorite hobbies?
If you chose green what is your favorite place?
If you chose blue what is one favorite memory?
If you chose yellow what is your dream job?
If you chose orange it's a wildcard and you can tell us anything about yourself!
My favorite place...
Right now with this time of year I've really been longing for
-Alright- the first five people to comment here are TAGGED! I'll be checking on you, too!


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Career Mentor
The e-Mentor Network is a service provided by the William Peace University Office of Career Services for our students and alumni.
Alumni have the opportunity to offer their wisdom and advice in various career fields to current students and their fellow graduates. The e-mentor network system is a service that assists students and alumni in finding mentors for career networking purposes. All contact is done on-line and your email address is always hidden. Students and other alumni are able to access the database to learn more about your respective career or industry with an option to contact you for further information or career advice.
Join Our Mentoring Network
Post a profile to help students and alumni prepare for their careers. This information is only accessible to other students and alumni.
Update your Mentoring Profile
Update your information, change your contact status, and more.
Career Center Staff
Barbara M. Efird, M.Ed., NCC, LPC
Office: Main Bldg., Room 18
Kathleen A. Monroe
Assistant Director
Office: Main Bldg., Room 17
Monday - Friday
8:00 a.m. - 5:00 p.m.
Career Center: Main Building


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WISN app users tap here to view images
We want to honor these brave men and women, and thank their families, for the sacrifices shared and the commitments made. Please take this opportunity to share your photos and videos of service members returning home to portraits honoring those who made the ultimate sacrifice.
Share your photos in the Honoring Our Heroes category so they appear in the slideshow . Remember to submit a good caption or story with the photo.
You can also send us your pictures by clicking on the "Upload Now" button below. It will automatically place your photos in the correct category.
Start sharing your photos and videos today! Not a member? Join u local-- it's quick and easy.


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Verify Enrollment Status, Degree, & GPA
The University of Minnesota Duluth, along with the National Student Clearinghouse, provides electronic verification of student degrees and enrollment to employers, employment agencies, credit card companies, background search firms, and various other businesses that offer products or services based on an individual's status as an enrolled student. This information is available 24 hours a day, 7 days a week, 365 days a year at www.studentclearinghouse.org, or call (703) 742-4200, M-Th 9am-7pm, or Friday 9am-5pm Eastern Time. Note: The National Student Clearinghouse does charge a fee for enrollment verification and degree verification.
Enrollment Verification Letter
An enrollment verification letter provides official proof of your University enrollment. You may need to certify your enrollment for student loan deferment, insurance discounts, or for requests related to your scholarships or your visa.
A verification letter can include any of the following:
- Your enrollment (for all terms or only the most recent term)
- For each term, your enrollment will be listed as full-time, 3/4-time, half-time, less than 1/2-time, or no units
- Cumulative GPA and credits (for all terms or only the most recent term)
- Expected graduation date (provided by the student)
- Degree/Certificate awarded
- Degree GPA (GPA as of the date your degree was conferred; available only for undergraduate degrees)
Access your Enrollment Verification letter
Students may access and print their Enrollment Verification from MyU: Academics.
- Select the Enrollment Verification link from the Enrollment Tools section
- Choose the information you would like to include in your Enrollment Verification
- Submit your request to view or print
- To request that the University send your enrollment verification to a third party, choose the "Request Institution to Mail" option from the drop-down menu and include the third party's contact information
Verification Facts & Policy (read me)
Request an Enrollment Status Verification letter
Download and submit the Request for Verification.
- Requests are free and processed in 2-3 business days.
- Make requests to One Stop Student Services in person, by mail, or by fax.
Request Loan Deferment
If you have received a deferment form from your student loan lender, One Stop Student Services can issue you a verification letter. Submit your request to One Stop Student Services in person, by mail, or by fax. More information about deferments and other exceptions to the definitions of full-time and half-time status is available at One Stop Student Services, 23 Solon Campus Center, by calling 218-726-8000, or via E-mail to email@example.com.


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UNIVERSITY PARK -- Ted Roof didn't have a lot of supporters after Penn State's first two games -- both losses -- but his friend and boss, Bill O'Brien, never lost confidence in the defensive coordinator.
Four games later, the heavy criticism once aimed at Roof has mostly disappeared.
"I don't pay attention to it one way or the other," Roof said of that early criticism. "If you listen to it, you let it affect you if it's good or bad. I base it on what I see on tape."
What he saw on tape the first two games was a defense that couldn't get off the field on third down, and that played a big role in the Nittany Lions losing to Ohio and Virginia. Those teams combined to go 22-of-35 on third down, including 18-of-21 in the second half.
Roof was in a tough situation at that point.
He already had replaced the popular Tom Bradley, whose defenses annually ranked among the nation's best statistically and who many Penn State fans wanted to see named the new head coach.
Instead, the top job went to O'Brien, who hired one of his best friends in Roof to be the new defensive coordinator.
Was Roof qualified, beyond being O'Brien's friend? Would his schemes work at Penn State? Is he even the best defensive coach on the staff, which also includes highly respected line coach Larry Johnson and linebackers coach Ron Vanderlinden?
After the two losses, many wondered about Roof's credentials and pointed out he was essentially forced out by coach Gene Chizik at Auburn a year after the team won a national title. Auburn fans criticized Roof's defenses, which ranked 60th nationally in 2010 and 81st last year, and he already had taken a job with another friend of his and O'Brien's, George O'Leary, at Central Florida.
Earlier this season, one of Roof's former players at Auburn, safety Demetruce McNeal, took this verbal jab:
"Last year we weren't coached very well," McNeal said after a 12-10 loss to LSU. "We weren't as smart as players as we are this year with a change on defense. Last year we put on kind of a clown show, a lot of guys not doing their work and not doing their job."
Despite those harsh words and the apparent falling out with Chizik, it turns out Roof wasn't the problem at Auburn. The Tigers rank 78th in total defense this season, allowing 416 yards per game, while PSU is 32nd, giving up 341 per game. (It must be pointed out Auburn has played a much tougher schedule, facing the likes of LSU, Clemson, Mississippi State, Ole Miss and Arkansas.)
"It's the media's job to observe and report and make sure they make their own opinions of what's happening on offense and defense," O'Brien said Tuesday when asked about the early criticism aimed at Roof. "But I can tell you that Ted is one of the best defensive coaches that I've ever been around.
"He's a multiple guy, he's an aggressive guy. The players respect him. They love to play for him, and he's done an excellent job."
The numbers, especially on third down, point that out. During the Lions' four-game winning streak, the defense has allowed:
n 15-of-55 third-down conversions (27 percent)
n Just 310 yards of offense per game
n Only 41 points on its own (Northwestern scored 14 more on a 75-yard punt return and after recovering a fumble at the PSU 17)
"When [O'Brien] hired me, he said, 'Here's how I want it to look and then go paint the picture,'" Roof said after the Northwestern game. "That's what our staff has tried to do."
Roof hasn't been able to paint the picture he envisioned.
He's an aggressive defensive coach who likes to play man-to-man coverage and bring a lot of pressure, but Penn State's lack of depth and experience in the secondary have prevented Roof from implementing his entire scheme.
"We've adjusted since the first week of the season," he said. "We've adjusted since that, and it's kind of evolved."
The defensive schemes have been more of a mix and match, Roof added, based on what the players do best. Some coaches will stick with their scheme regardless of if they have the right personal to run it, but Roof doesn't believe in that.
"You've got to evaluate what the strengths of your kids are," he said. "For me to stick this scheme in that doesn't fit what our kids do, that's ridiculous because you're going to get beat and it's going to be bad.
"You figure out what your kids can do, and you work like heck to get really good at it, build an identity, play hard, play fast, play physical and pay your money and take a chance."
The Lions can't get the first two games back and have to live with those losses, but the most important thing to O'Brien is that the defense figured out what it was doing wrong in those games and made adjustments.
"Football is about improvement," O'Brien said. "It's about improvement of players, it's about improvement of coaches, it's about being disciplined, it's about understanding who you're playing, and each game is different. So I think that all of us have shown improvement throughout the year."
O'Brien then didn't hesitate to give his good friend a vote of confidence.
"Ted Roof has done a really good job," he said, "and I'm glad he's here."


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Hunger Hits Home
A new Food Network produced documentary, HUNGER HITS HOME, narrated by Oscar®-winning actor and longtime anti-hunger activist Jeff Bridges focuses on the devastating hidden crisis of childhood hunger in America. The film is part of an ongoing partnership between Food Network and Share our Strength, whose No Kid Hungry initiative aims to eradicate child hunger in America by 2015 by surrounding children with nutritious food where they live, learn and play. HUNGER HITS HOME premieres on April 14th at 8pm/7pm central on Food Network. www.foodnetwork.com/hungry


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1:32 minutes
Airs Wednesday April 28th at 10/9c! When Dominic, a former sociopathic hit man with a love of explosives, falls in love for the first time, Mary fears that he won\'t handle rejection very well. Meanwhile, the WitSec office welcomes a new financial manager, and Mary says her goodbyes to Raphael. Guest starring Louis Lombardi and Erika Alexander! Visit the official fan page http://www.facebook.com/inplainsight . Follow us on Twitter! http://twitter.com/InPlainSightUSA


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Developers of DTC Genetic Testing Are...
Quadruple Helices Appear To Have Role...
Wall Street Decline Takes Its Toll...
LC-MS Gains Favor Due To the...
The quest for personalized medicine adds to the complexity of today's scientific questions. Drug discovery efforts require access to larger arrays of biosamples, and demand is exceeding supply, fueling the growth of the biobanking market.
"Humans are inherently variable, which is good for evolution but bad for drug discovery. More samples equal more reliable results. However, cost and ease of access tend to limit the number of samples used," explained Paul Whittaker, Ph.D., director and unit head for preclinical biomarkers, respiratory disease area, Novartis.
Experts met at SMi Group's recent biobanking conference to discuss the challenges the industry faces, from supply issues, standards development, and sample tracking across multiple organizations to potential uses for banked clinical trial samples.
Sources for human material are increasing, ranging from those that provide postmortem material, such as the International Institute for the Advancement of Medicine (IIAM), to consortia that provide samples from living donors with specific diseases, such as the Lung Tissue Research Consortium. Depending on source, varying amounts of donor information are supplied with the human materials.
The Medical Research Council and Association of the British Pharmaceutical Industry COPD consortium aims to identify more homogeneous groups of patients using extensive and standardized clinical and physiological testing.
"The term 'well-phenotyped' could mean an exhaustive list of clinical, physiological, and molecular parameters that would maximize use of human tissue for a range of experimental uses, or it could be a more restrictive set of parameters that are highly relevant to the particular hypothesis being tested," continued Dr. Whittaker.
"For some lung diseases, like interstitial pulmonary fibrosis and chronic obstructive pulmonary disease, there is good access to high-quality, well-annotated material, and for others, such as pulmonary arterial hypertension, academic collaborations are the main way to access material.
"It is clear that no one biobank can meet all the needs for biomedical research and that biobank networks will be necessary to make collections more widely available."
An exciting development is the emergence of virtual biobanking, where companies provide a single point of access to a range of biospecimens. Using networks of ethical sources, they find the tissues required to the specifications provided by the requester, and then deliver them to the requester. This streamlines the procurement of tissue and benefits all parties.
Biospecimens are most frequently used in drug discovery research. To answer questions about drug mechanisms in the patient, biospecimens obtained during clinical trials are invaluable.
Clinical trial protocols specifically state how collected samples will be used and how long they will be retained. Depending on consent parameters, biospecimens collected during a clinical trial are often discarded after the study report is finalized.
"Most companies are sampling more, increasing and building biorepositories," commented Mads Roepke, Ph.D., senior scientific advisor, clinical pharmacology, LEO Pharma. "The discussion is what to use the samples for. Some companies impose strict internal barriers for use of samples, and bank samples only to use if safety or efficacy issues arise. Others are more collaborative across divisions, and use them for drug discovery and development in additional cross studies.
"Use of samples across studies requires special approval by the regulatory committees and consent from participants. When you are outside the parameters of the initial study protocol and wish to store patient samples for later studies with a new scope, you move into biobanking and the associated regulations, including questions of sample analysis and reporting.
"At LEO Pharma, we are currently looking at using biospecimens obtained from patients in one program for investigations in other programs where drug candidates with similar mechanisms of action and/or the same patient types are studied. Clinical data associated with the sample would be more specific to the disease. By maximizing the use of patient samples, we could increase our understanding of disease biology, and advance research on future therapeutics for the benefit of patients."
"Good quality assurance in biobanking is an end-to-end process," remarked George Tokiwa, Ph.D., associate principal scientist, Merck Research Laboratories. "In a pharmaceutical company, you need to be sure that you plan, collect, process, track, and store future-use specimens in a manner that maximizes specimen utility, and minimizes risk to specimen integrity."
Quality-management processes, documentation and the physical attributes of the specimen are all crucial. Specimen collection requires compliant, robust methodology and validated processes that safeguard specimen integrity. Good IT infrastructure, a robust comprehensive inventory system, specimen oversight/governance, and project management ensure chain of custody.
Merck utilizes processes to track specimen permissions, consent reconciliation, and other possible restrictions or attributes of the specimens, e.g., restricted to disease-specific use. Consent expiration dates are tracked, and specimens flagged and destroyed as required. In addition, since certain specimens or specimen analytes may be stable only for a finite period of time, these specimens are tracked and flagged as suspect when appropriate.
During the course of each clinical study, performance metrics are used for trend analysis to determine if intervention or remediation action is necessary. An example is future-use genetic specimen collection rates and DNA quality. Each study site's performance is monitored and compared to expected collection rates, DNA yields, and quality.
"Biobanking specimens for long-term storage and future use can be an expensive proposition. We want to ensure maintenance of material that is of value," continued Dr. Tokiwa. "We developed a specimen retention algorithm, a set of decision trees to assess the biorepositories' inventories and determine how best to disposition the specimens. With appropriate stakeholders' feedback we are able to objectively decide if specimens should be retained or discarded."
Merck Research Laboratories recently signed a partnership agreement with the National Center for Cardiovascular Diseases Fuwai Hospital for collaboration on the development of China's first biobank for cardiovascular and metabolic biosamples.
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text:
DeRosa Not Too Right-Handed Today
Mark DeRosa drove in four runs with two long home runs and a sacrifice fly and scored another run after reaching base on a double, as the Cleveland Indians defeated the Cubs 7-5 before 13,097 fans at sunny and breezy Dwight Patterson Field at Ho Ho Kam Park in Mesa this afternoon.
DeRosa's two home runs were both monster shots, one crashing into the scoreboard in LF, and the other one missing the scoreboard only because it went over the fence too far toward CF. But the double was even more incredible, as it hit the upper part of the 30-foot high "Green Monster" (Batter's Eye) in dead CF.
All of the DeRo blasts were hit off Cubs starter Ted Lilly, who would have had a nice final line if it wasn't for his ex-teammate (both with the Cubs & Team USA) crushing his pitches every time he came up to the plate againt him. If I didn't know better, I would say there must have been some kind of pre-arranged deal for Lilly to throw "BP fastballs" to DeRosa to allow the ex-Cub to put on a long-ball dsplay in front of the assembled Mesa multitude.
Ex-Cub Kerry Wood also returned to Ho Ho Kam Park today for the first time since signing as a Free-Agent with the Tribe during the off-season, and pitched the 7th inning against his former club. .
Both DeRosa and Wood received loud ovations from Cub fans when they were announced.
The Indians took a 2-0 lead in the top of the 1st inning off Lilly, when lead-off man Grady Sizemore lined a single to the outfield and DeRosa hit his first HR (the one to the CF side of the scoreboard). But Lilly then retired eight in a row quite impressively (6-3, Ks, Ks, F-8, Ks, F-8, Kc, Ks).
But DeRosa broke Lilly's magic spell, hitting a solo HR (the one off the scoreboard) with two outs in the top of the 3rd, giving Cleveland a 3-0 lead.
The Cubs loaded the bases in the bottom of the 2nd against Indians starter RHP Fausto Carmona on two singles and an error, but Lilly and Alfonso Soriano struck out, leaving the bases full.
The Cubs did score in the next inning, however, Ryan Theriot grounded a single to lead-off the 3rd, and then with one-out, Milton Bradley (hitting LH) smashed a home run over both bullpens in RF, making it 3-2 Indians.
Lilly gave up a couple of harmless singles in the 4th and had retired the first two men in the 5th, when DeRosa unloaded his moon-shot off the CF Batter's Eye for a two-out double. Victor Martinez followed with a line shot RBI single to score DeRosa from 2nd, and the Indians took a 5-2 lead.
The Cubs came back to score a run in the bottom of the 5th, as Theriot bounced a double down the LF line and Derrek Lee hammered a single between 2nd & 3rd into LF to put runners on 1st & 3rd with no outs. Milton Bradley grounded out to the 1st baseman (unassisted) as Theriot scored and D-Lee took second, but Aramis Ramirez and Mike Fontenot grounded out to end the threat.
Lilly had thrown 73 pitches through five innings, and I really thought that was probably going to be his limit. But he did return to the mound to start the 6th, although there was activity in the bullpen. And Lilly was indeed clearly tiring as he began the 6th, walking Ryan Garko and Ben Francisco (his first two walks of the day), before getting relieved.
For the day, Lilly pitched five innings (plus two batters in the sixth), allowing four runs (all earned) on seven hits (two HR) and two walks. while striking out eight. He threw 92 pitches (66 strikes), with a 2/5 GO/FO. Other than when he faced DeRosa, I thought he looked pretty good.
Chad Gaudin relieved Lilly, coming into the game in a tough situation, with no outs and runners on 1st & 2nd. But he retired Jamey Carroll on an infield pop up, Tony Graffanino on an F-8 fly out, and pitcher Carmona on a 5-3 bunt out to get out of the jam.
The 7th was another story, however, as Gaudin first got pounded, and then could not find the strike zone.
Grady Sizemore roped Gaudin's very first pitch of the 7th into the RF corner for a lead-off triple. DeRosa then hit a F-8 SF to deep CF to score Sizemore, before Victor Matinez lined a single to CF. Gaudin struck out Jhonny Peralta, but AAA OF George Lombard turned a Gaudin offering around, launching it over the two bullpens beyond the RF fence, just about exactly where Bradley hit his dinger earlier in the game. Gaudin walked Ben Francisco before striking out Wilson Valdez for the final out of the inning. .
In his two innings of work, Gaudin allowed three runs (earned) on three hits (including a triple and a HR), and one walk, with two strikeouts. He threw 39 pitches (23 strikes) over the two innings, but he needed 29 pitches to get out of the 7th, while throwing only 15 strikes that inning. He certainly did not do anything to ensure a spot in the Cubs bullpen with today's outing.
On the other hand Rule 5 RHP David Patton continued to make a favorable impression, working an easy ten-pitch 1-2-3 8th, getting two strikeouts (both swinging) around an F-7 fly out.
Kerry Wood faced only four Cubs batters in the bottom of the 7th, getting Alfonso Soriano on a fly out (F-7) to lead off the inning, before walking Ryan Theriot on four pitches. But Micah Hoffpauir flied out harmlessly F-9, and Milton Bradley was called out on strikes (and he knew it, too, as Woody must have fooled him with a 3-2 slider).
The Cubs did narrow the score to 7-5 in the bottom of the 8th against Japanese RHP Masahide Kobayashi. Aramis Ramirez doubled to the deepest reaches of CF to lead-off the inning, before Reed Johnson unloaded a two-run HR off the scoreboard beyond the LF fence. Koyie Hill then followed with an opposite-field near HR sliced down the LF line (it was caught by the left-fielder, however), and Joey Gathright lined a shot into left-center, using his speed to reach second-base on a "hustle double." But Aaron Miles and Alfonso Soriano grounded out to end the threat, and the score remained 7-5 in favor of the visitors. ,
LHP Neal Cotts worked an 11-pitch 9th (nine strikes), striking out DeRosa before allowing one single to the outfield and an infield single (Aaron Miles threw the ball away for an error attempting to get the runner at 1st base, allowing the runner arriving at 2nd base--Victor Martinez--to advance to 3rd), but Cotts then got the tyhe left-handed hitting Lombard to tap into a "room service" 4-6-3 DP to end the inning on the very next pitch.
The Cubs attempted to mount a rally in the bottom of the 9th off Cleveland's hard-throwing LHRP Rafael Perez, but it fizzled pretty quickly. Andres Blanco popped out to open the frame, and then Micah Hoffpauir struck out (swinging). But "strike three" got away from catcher Victor Martinez, and Hoffpauir was able to reach first base when Martinez's throw hit Hoffpauir in the back while he was running to 1st (and he was running in the lane, so it wasn't interference). But So Taguchi struck out swinging (and looked terrible in the process, as he swing late on every pitch), before Esteban German grounded out sharply 6-3 on a 3-2 pitch to end the game and seal the Cactus League victory for the Indians.
BTW, Andres Blanco, So Taguchi, and Esteban German were all sent to Minor League Camp after the game (and they were probably the last to know, too), but FWIW, LHP Mike Stanton was warming up in the Cubs bullpen during the bottom of the 9th in case the game had gone to extra innings, so he is definitely still around. I don't know why, but he is...
Besides Bradley's HR and three RBI and Reed Johnson's two-run dinger, several other Cubs had good days at the plate today. Ryan Theriot reached base all four times he batted on a double, a single, and two walks, Joey Gathright had three hits (two singles and the "hustle double") and also made a nice running catch at the fence in left-center, and Aramis Ramirez had a single and a double.
The Cubs travel out to Surprise (which is halfway to California as far as I'm concerned) tomorrow to face the Kansas City Royals, before returning to Mesa on Tuesday.
Re: DeRosa Not Too Right-Handed Today
Re: DeRosa Not Too Right-Handed Today
Finally some fantasy good news.
Re: DeRosa Not Too Right-Handed Today
and Scott Eyre is STILL having money problems!
Re: DeRosa Not Too Right-Handed Today
I am not sure what day is trash day in Mesa but could the Cubs leave Mr. Gaudin out by the curb this week. Please.
Re: DeRosa Not Too Right-Handed Today
Speaking of trash, Muscrat says the Cubs have cut ties with Mark Pawelek. Thats Harvey, Johnson, and Pawelek in one week. Sad.
Re: DeRosa Not Too Right-Handed Today
Glad they cut that guy. 21 year old lefties with mid 90's fastballs have no place in this organization.
Get with the Cubbie way kid!!!
Re: DeRosa Not Too Right-Handed Today
Yeah, unless he's really injured or has good a bad attitude, this is just dumb. Stash him away in A ball and let him see if he can figure it out.
Re: DeRosa Not Too Right-Handed Today
This is disappointing. What is gained by cutting ties with Pawelek at this point?
Re: DeRosa Not Too Right-Handed Today
I'm 99% sure I remember reading somewhere that Pawelek is like Andy Sisco, in that he has a real attitude problem and refuses to take direction well. Maybe Phil can elaborate. If true, then they cut him because he is a bad influence on other young pitchers, at least that's the reason they gave for giving up on Sisco via the Rule V.
I tend to giving the Cubs the benefit of the doubt on these things, they've usually made the right call.
And I'm near-certain Pawelek's money was as a signing bonus, so that's a sunk cost, making it even easier to let him go. He certainly has no trade value.
Re: DeRosa Not Too Right-Handed Today
Who needs DeRosa's bat when we lefty Gabor? sigh..........
We're going to miss DeRo.
I don't have the link but, surprise, Rich Hill is on the 15-day DL for Baltimore.
Re: DeRosa Not Too Right-Handed Today
a little 3/44 on that Mike Vail.
Re: DeRosa Not Too Right-Handed Today
Koyie Hill won the backup catcher job.
Now sit back and wait for Rob to post it.
Re: DeRosa Not Too Right-Handed Today
Stanton also released, per Muskrat's blog.
Nav, relax, you posted lineups yesterday in an old post and Rob posted the lineups - as usual - in the new game thread. I don't really think he needs to give you credit for beating him on something like lineups by about 10 minutes.
Re: DeRosa Not Too Right-Handed Today
What the hell are you talking about? Who gives a shit about who posted a lineup first.
Re: DeRosa Not Too Right-Handed Today
My bad, I went back and looked, it appears you were bitching about Rob posting the Gregg over Marmol announcement after you had posted it in the comments. But I agree with your point: "Who gives a shit who posted it first?"
Your first post under Rob's thread yesterday was a whiny Scott Eyre comment; and now this comment about Hill over Bako. Is Rob not supposed to post anything if it shows up in the comments first? I don't get it.
Re: DeRosa Not Too Right-Handed Today
Navigator is five cards short of a full deck, there's no point in trying to figure it out. But I'll happily relay the way I do things.
MOST (not some, not a few, MOST) of our readers don't read the comments, so if something is worth posting that may have been covered in the comments, I will post it in a story. If it's something I was legitimately tipped on by someone in the comments or on another blog, I'm usually pretty good about giving them credit, particularly radio reports which I don't listen much of. If it's something I read in my Google Reader or on another website and it happened to be covered in the comments as well, I don't really see the point in crediting them for the find. Sometimes I do (usually if it's not a source in my Google Reader), sometimes I don't....but it's really no big deal to me.
And if you're legitimately upset about it, I don't care. I really don't.
Re: DeRosa Not Too Right-Handed Today
Before making any new post you should always review all the comments for the last week to make sure that someone didn't hurridly jot down one sentence of information which probably came from the same source as your information so you can credit him with 'breaking the story' at www.thecubreporter.com.
Re: DeRosa Not Too Right-Handed Today
Once again... you really don't get it, do you?
Do you really not think that fairly significant roster moves and decisions on roles don't belong on the front page?
If you want to feel like you are breaking news... go start your own blog.
Re: DeRosa Not Too Right-Handed Today
Sullivan is strongly of the opinion that Lilly was throwing BP to DeRosa.
Also, Donnie Veal seems to be ending the spring with a bout of wildness--twelve walks in his last eight innings.
"It is a stretch anytime you take a player out of Double-A and put him in the big leagues," [GM Neal] Huntington said.
Sure, but Veal's wildness held him in AA for two years.
Re: DeRosa Not Too Right-Handed Today
that first link says they're going to leave Kerry's corner locker vacant for the season out of respect to Kerry.
That seems a bit much. I love Kerry and all, but he was a bit more promise than performance in his 10 years with the team.
Re: DeRosa Not Too Right-Handed Today
Sure, over the course of the past 10 years it seemed like he was injured more often than he was healthy, but the times when he did perform were often so spectacular that they made me forget about the lost seasons.
I also think this is Cubs management sending a message that guys who put the team first and lead by example will be treated accordingly, even after they leave. Try to think of another player who felt guilty about taking a big paycheck while injured so he signed a below-market deal just to try to repay the team? That's the Kerry Wood I remember, and that's the guy the Cubs are honoring this season.
I've said this before, but it's worth repeating - it's really nice for a change to have a star player leave before he overstays his welcome and the fans turn on him.
Re: DeRosa Not Too Right-Handed Today
Re: DeRosa Not Too Right-Handed Today
1. Agreed. The headline definitely made me laugh. Then I wallowed in bitterness for two and one half seconds. Then I read the article.
2. Isn't Lilly pretty competitive?
Re: DeRosa Not Too Right-Handed Today
Recent comments
first game for lester giving up more than 2 runs since july 24th. hell of a run.
doh, yes...dunno what happened there. jake arrieta is all "bro wut?"
lester going for #20...cubs haven't had a LH (thanks jpep for the correction) 20 game winner since d.ellsworth in 1963.
fwiw, all the games are free on mlb.tv
Short rest for MadBum would be 2 days. WC game is Wed., Games 1 & 2 are Friday/Saturday.
A left-handed one...
J-Hey not finishing with an offensive onslaught.
If Geoff Blum could be a Playoff hero, there is hope still...
Giants scare me. I think you're wrong about Bumgarner, he would pitch on short rest for Game 2 and then full rest for Game 5. Cueto would go Game 1, then short rest in game 4. Add in some really tough outs in that lineup and I want nothing to do with them. With that rotation they can easily steal a series.
Cards are a tough matchup. The rivalry evens out their comparable lack of talent. And like someone said, they love HRs, which is how to beat the Cubs. The upside is that I would feel really good about Lester twice against STL.
j.buchanan with a nice start...5ip 2h 1bb 3k, 0r/er
zobrist with 2HR and a double through 8
heyward 0-4 :(
Mark Gonzales @MDGonzales
Soler likely to return Sunday, Maddon says
Right now, I'd like to see the Mets first, Giants 2nd.
I believe that since most of the team from last years' NLCS is on the squad this year, they will really amp their game up even more to kick their ass in payback for 2015.
The Giants just do not have the depth in years past, and I think all things equal - and at Wrigley - they could handle them.
I do not want to see the Cards, period. Or their fans, media, or Joe Buck.
I don't want to play Braves in the first round. Any friggin team in the league can win 3 of 5..I hate the first round. Furthermore, I wanted to play the Marlins in 2003 and the Mets over Dodgers last year.
With that said in reverse order:
3. Cardinals: It will be devastating to lose in the first round, but even worse to their main rival. It is increased incentive for the Cardinals, especially after last year. Cards would have nothing to lose, Cubs have everything to lose.
2. Giants: Rotation in the playoffs scare me a bit, but what a lousy team.
1. Mets--because of the losses in the rotation
2. Giants--because they're not the team they were BUT they maybe have bullshit even-year magic?
3. Cardinals--because rivalry and not making the playoffs hurts them more than losing in the NLDS plus getting eliminated by them in the playoffs would make for horrible sports commentary next throughout next season.
Who's asking?
CLE/DET rained out last night already, possible rain-outs in New York (vs. Baltimore), Boston(vs. Toronto) and Philly(vs. Mets) this weekend too.
Not only games involving playoff spots that would need to be played, but any that involve home field advantage.
I got the first one! Second one I'm not even sure what even/odd betting is.


text:
Thursday, June 27, 2013
Bishop England - Valedictorian
Justin Sindoni grew up in New Jersey and moved here his sophomore year. The transition from public school to private school and moving from the north to the south made him a little nervous. But soon this academic whiz kid settled in and made great new friends.
Having been named Valedictorian for Bishop England's class of 2013, he plans to attend the University of South Carolina Honors College, majoring in biology.
His hope is to go to medical school or have a career in biological research.
He attributes hard work, and lots of studying to his academic success. "I like to do well and I put a lot of effort into my academics to succeed," he said.
He said his mentors have been his parents who have, of course, supported and guided him through life.
He also said he could not have done it without his teachers who played a large part in how he succeeded, always offering extra help and understanding.
"Also and my friends," he said. "Through the entire learning process they were there to reenergize me."
Sindoni's interests are music, clarinet, science, biking and reading. His extra-curricular activities in high school included Orchestra Club vice president and co-founder, Key Club secretary, Senior Board homeroom representative, Mu Alpha Theta treasurer, Archery Club and National Honor Society.
And his advice to high school students, "always be yourself everyday and try to improve the world around you. And through your own actions make the world a better place."
Bishop England - Salutatorian
April Newton was named Salutatorian at Bishop England High School. She is going to Clemson University in the fall and will major in Industrial Engineering. She chose that academic path because she likes math and science, she said.
During high school Newton played varsity basketball and piano. She participated in the National Honor Society, Mu Alpha Theta, Band of Buddies (a club that helps the learning disabled as mentors and friends) and The Key Club.
Newton said that the biggest challenge in balancing extracurricular activities and school work was time management.
She explained that the amount of homework and being able to get it all done on time could be difficult.
"But I was able to succeed because of hard work," she said. Newton's mentors through life have been her parents and her grandfather. "They are just great people and they taught me how to be a good, successful person," she explained.
And her advice to up-and-coming high school students, "Just know you can do anything with a little faith and hard work."
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text:
It's no doubt
impressive when today's compact sedans -- which are loaded down with
hundreds of pounds of safety gear and chassis reinforcements not
found on vehicles from decades past -- top the 40 mpg mark. However,
it's even more impressive when midsize sedans approach that mark as
You know about
the compact 2011
Chevrolet Cruze and 2011
Hyundai Elantra which can hit 40+ mpg on the highway. Hyundai's
2011 Sonata midsize sedan can achieve 35 mpg on the highway in its
base configuration. GM is now flaunting its 2012 LaCrosse which will
come standard with eAssist technology (which will provide up to 37
mpg on the highway) and will be priced at roughly $30,000.
"It's a very
integrated powertrain system, with no compromises in driving
performance, shift quality or ride and handling," said Daryl
Wilson, LaCrosse lead development engineer. "We believe this
combination points to the future of vehicles powered primarily by an
internal combustion engine."
The LaCrosse
will be powered by a traditional 2.4-liter direct injection
four-cylinder engine which generates 180 hp. The engine is mated to a
6-speed automatic transmission. However, GM also includes its next
generation "mild hybrid" system which it calls eAssist. On
the LaCrosse, the eAssist electric motor provides an additional 15 hp
and 79 pound-feet of torque during acceleration. Other features to
improve fuel economy include an engine start/stop function and
regenerative braking.
lithium-ion battery mounted in the trunk powers the electric motor,
but it encroaches on cargo-hauling capabilities. Maximum cargo
capacity drops from an already lackluster 13.3 cu ft to just 10.9 cu
However, the
benefits in fuel economy are huge. EPA ratings jump from 19/30 mpg
(city/highway) to an impressive 25/37 mpg. The city rating falls
short of Lincoln's
MKZ Hybrid which pulls in an impressive 41 mpg, but that vehicle
is priced higher at $35,180.
"The eAssist
system is more than just the next-generation BAS system. The ability
to integrate regenerative braking with the latest lithium-ion battery
technology creates a system that delivers significant fuel-efficiency
gains that customers will enjoy," said Steve Poulos, global chief
engineer of the eAssist system. "Being able to provide electric
boost to the powertrain system during heavy acceleration and grade
driving enables the LaCrosse transmission to operate more
efficiently, while the added functionality of engine start-stop and
fuel shut-off during deceleration provides added fuel savings."
Official pricing
and availability of the Buick LaCrosse with eAssist should be
available closer to its launch later next year.
quote: What is it with union bashing lately? Unions are an American institution and guarantees YOUR right to organize if you wish. It's part of the constitution so many of you claim to believe in.
quote: In my opinion, you've "exposed" nothing. These guys did everything in front of cameras, and didn't try to hide ANYTHING.
quote: Why the assumption that everyone who is unionized works at Walmart or is poor? That's clearly your elitist attitude taking over.
quote: Somehow, you have this weird idea that people who are not educated or have low-paying jobs have no right to speak up for themselves.
quote: This whole me, me, me attitude is NOT what this country was founded upon.
quote: Furthermore, if your "private pension retirement plan goes bust", don't look to help from anybody but yourself.
quote: You want me to post tons of situations of private corporations taking advantage of non-unionized workers? There are many.
quote: You had to search for that bogus one you posted (I saw that one on Fox News too.
quote: Also, in those other countries they actually tax their rich people, those employers then in turn, invest in their employees. I can't name other countries where the more money you make, the percentage you pay in taxes actually goes down.
quote: Unions are an American institution and guarantees YOUR right to organize if you wish. It's part of the constitution so many of you claim to believe in.
quote: I'm different with regard to labor. I guess I could never make it in business because though I know the goal is to make money....how much is enough? How much wealth does one person need to accumulate before it's enough that others cannot compete with him/her?
quote: By Spuke on 11/15/2010 7:13:30 PM , Rating: 1
quote: You've have republican-controlled congress before. Were they any more sane than the outgoing one?
quote: Just have one of those "well-run", too big to fail corporations starts to go belly up. They'll be the first in line to ask for a handout.
quote: That outrageous CEO pay is then passed on YOU and myself in the form of higher costs. You wanna see how much of the CEO pay is none anyone's business?
quote: But, if anything goes wrong within a company, the CEO will always take some heat.
quote: Really? guys like you always praise the business model that's "worked for decades" talking about how this wouldn't happen in business or that wouldn't happen.
quote: By the way. That quote is from 2006
quote: Your posts are proof positive that greed and selfishness have taken over.
quote: Then we see all these stories of people at the top making outrageous sums of money EVEN WHEN THE COMPANY IS LOSING MONEY.


text:
Sources: Engadget, The Verge
quote: This isn't just an Apple tablet made to a budget. This isn't just a shrunken-down iPad. This is, in many ways, Apple's best tablet yet, an incredibly thin, remarkably light, obviously well-constructed device that offers phenomenal battery life. No, the performance doesn't match Apple's latest and yes, that display is a little lacking in resolution, but nothing else here will leave you wanting. At $329, this has a lot to offer over even Apple's more expensive tablets.


text:
Not surprisingly, it is mostly 'avid cyclists' doing the debatin' so right there we could figure that it probably wasn't going to have much to do with anything concrete and certainly not with mainstreaming urban cycling. Many 'avid cyclists' have long had a hard time with cycle chic. We know that. It's been a rather repetitive discussion for almost five years. Sub-cultures have a tendency to become defensive when their territory is ''infiltrated' by regular citizens.
We're fast approaching the five year anniversary of what has later been called The Photo That Launched a Million Bicycles. We're repeating ourselves, certainly, but let's backtrack a bit.
In late 2006, the bicycle didn't exist in the wider public consciousness anywhere in the world. It had largely been forgotten in vast swathes of the planet. In many cases an entire generation had forgotten the simple imagery of Citizen Cyclists riding bicycles in their regular clothes. As transport, not some hobbyist weekend activity. This blog changed all that. This is where Cycle Chic was founded. Where the phrase was coined.
The story is well-known to most who visit this blog: THE HISTORY OF CYCLE CHIC™ - THE PHOTO THAT LAUNCHED A MILLION BICYCLES
From the very first week of the existence of this blog, it poured in with visitors. Simple photos of regular citizens going about their daily business on bicycles here in Copenhagen - the City of Cyclists - amazed people from around the world. This is the power of the internet, of course. One photo in Copenhagen brought the bicycle back to the public consciousness and launched the bicycle boom we are currently enjoying. In the 1970's it took a global energy crisis to bring the bicycle back, however briefly. Now it has been accomplished with a handy camera on a November morning, Flickr.com and Blogger.com. Amazing.
The 'value' of cycle chic was apparent from the beginning. The fashion industry, recognizing a trend, were quick to get on board. We here in Copenhagen started recieving requests for permission from many regions to start copycat blogs. A whole lot of people saw a value in Cycle Chic. Very few of them were 'avid cyclists', which was a good thing. Now there are easily over 140 cycle chic blogs around the world. That's quite a few people who see a 'value' in cycle chic and the message we bring to the world.
I now travel that same world giving various keynote speeches and one of them is about how to promote urban cycling. Four Goals for Promoting Urban Cycling. A template for cities who wish to increase the number of citizens on bicycles. In that talk I talk about marketing and about Cycle Chic. About how we should start applying basic marketing techniques to urban cycling. Mainly because the bicycle advocacy we've seen over the past 40 years has been a flop. It leans up against environmentalism with it's tone, message and sanctimonioius halo. The problem is that environmentalism is the greatest marketing flop in human history, which means it's not much of a lamppost to lean up against.
Forty years of activism and awareness and what do we have to show for it? Not much at all. All that finger pointing, all those guilt trips and the mainstream audience has turned deaf. It's like bicycle advocacy. All that crap about "it's healthy to ride a bike!" and "its green to ride a bike!" doesn't get people to ride bicycles. Especially when it's 'avid cyclists' doing the advocating. There are exceptions of course, but most bicycle advocacy is sub-cultural groups who wish that everyone rode a bicycle just like them. And can fix a bicycle just like them. And so on. It's the same with most sub-cultures. They are protective of their hobby and are wary of newcomers. Stamp collectors wish everyone loved and respected stamps as much as they do. They wish we would all place the stamp carefully and lovingly at a right angle to the edges of the envelope. But we all don't do that. I just slap 'em on and slide 'em into the slot.
What Cycle Chic has done and continues to do is inspire Citizen Cyclists. We are a sartorial replacment for 'avid cyclists' and their monotone ramblings. We speak to the 95% of the population, not the 5%.
Take one look at some of the testimonials we've recieved over the years. Everywhere I travel with Cycle Chic and Copenhagenize I meet people who humble me with their stories about how Cycle Chic made them buy a bicycle and made them realise that they didn't have to be a 'cyclist' to ride a bicycle. It inspires me. It moves me. Sometimes it makes tears roll down my cheeks.
One of the sites involved in the 'internet debate' writes that "The concept of "cycle chic" has been controversial almost from the moment it started."
No, it hasn't. Look at our timeline of press mentions about our blog and about cycle chic, starting in January 2007. It wasn't controversial at all.
People started getting their (lycra) panties in a knot much later. When it became clear that Cycle Chic was effective at getting people to ride bicycles. We have seen a long list of whining in articles, blogposts, letters to the editors from 'avid cyclists' who bitch about 'fashionistas' now riding bikes. Like it's a bad thing.
Let's back track even further. To the late 19th century. Until the invention of the Safety bicycle - the diamond-shaped design we still use today - bicycles were the exclusive domain of a sub-culture. Upper middle class to upper class men. (sound familiar?). When the safety bicycle appeared it transformed society more quickly, more effectively than any other invention in human history. Liberating the working classes. Liberating women for the first time. It wasn't all rosy. When women and working class citizens started riding bicycles, the sub-cultures started ridiculing them. Spitting on them, even. The mainstream was infiltrating their private little world. Regular citizens were taking to the bicycle and enjoying all the transportational benefits it provides. History is repeating itself in many ways.
The bicycle was fashion as well as transport back in what I call Bicycle Culture 1.0. Just as it is again now. Cycle Chic is just a phrase I coined to describe the effortlessness, gorgeousness, goodness that the bicycle can bring to society. The way we sold bicycles between 1890-1950 - give or take - was excellent marketing. It was Cycle Chic. Just look at many of the posters used for this purpose.
Someone tweeted "I'm more & more convinced that PR/branding campaigns to make cycling look chic & attractive do more harm than good."
Couldn't disagree more, but then again, sounds like a 'cyclist' talkin'. A 'cyclist' who can't reflect themselves in the mirror now placed before them. Citizen Cyclists - of all age and wage brackets, of all races, in so many countries embracing the bicycle.
What have we seen over the past 4 - 4.5 years with Cycle Chic? A long line of fashion companies embracing the bicycle in their campaigns. A new generation of citizens returning to the bicycle in their regular clothes - for transport, errands, etc. Who gives a shit if the bicycle is a fashion or lifestyle accessory for some? The most important thing is reestablishing the bicycle on the urban landscape. That requires a lot of Citizen Cyclists and a lot of bicycles to provide the necessary symbolism in our cities. We are well on our way but we are far from the goal in many cities.
What else can Cycle Chic do? It can contribute to social inclusion. A couple of years ago I was speaking in New York City. I chatted with a couple of nice guys - white, middle-class 'cyclists' and made the mistake of calling the many recent immigrants who deliver goods by bicycles in the city 'working class heroes' and the 'backbone of the cycling world'.
The two guys were shocked. "Those guys are forced to ride because they can't afford a car. We CHOOSE to ride", I was told. They saw no similarities between themselves and the delivery men.
If we are to succeed in mainstreaming cycling, we need more social inclusion. We have to give the bicycle back the same status now enjoyed by cars. When delivery men see wealthier citizens exhibiting Cycle Chic, they won't see a car. They'll see an attractive lifestyle. They'll see a bicycle in their cross-class societal mirror. Cycling sub-cultures aren't exactly helping, but Cycle Chic can and is.
What is most interesting about the evolution of Cycle Chic is that we at Copenhagenize Consulting, who run the blog and administer the trademark, are seeing a whole new group of people asking to start a blog. Municipalities and organisations. For example, when I was in Montreal recently to help launch Montreal Cycle Chic, it was Canada's largest cyclist organisation Vélo Québec who was behind the blog. The City of Murcia, in Spain, has a blog. Cycle Chic Belgium is run by a passionate group at an environmental NGO. At the recent Cycle Chic Bloggers Conference in Barcelona, we took part in events with the Catalonian bicycle NGO and were invited on a tour of the city of Saint Joan Despi by the mayor himself. We are currently discussing other blogs for other municipalities and organisations. Now more than ever before.
Cycle Chic has a value and while a small group may not approve of it, all the right people embracing it. People who wish to transform their cities using the bicycle as an effective tool.
It's not surprising that the countries and cities where urban cycling is booming and growing fast are places where there is little sub-cultural influence. When Citizen Cyclists are allowed to take to the bicycle without worrying about 'fitting in' with the fancy bikes, expensive clothes, gear and helmets of a cycling sub-culture, mainstream bicycle culture is provided with fertile soil. Check out Behavioural Challenges for Urban Cycling.
Cycle Chic is couture. Style. Fashion. Not profiteering like we're seeing in some places and not people capitalizing on the brand without asking permission but rather regular fashion for regular people. On this blog and many of the others we show lovely clothes on bicycles. People dressing for their destination, not their journey. We don't fuss much about the bicycles because it's not about the bicycle. It's about people on bicycles. It's about getting more people onto bicycles. It's about social inclusion. It's about transforming our cities and making them nicer places to live.
Cycle Chic continues to grow. It has been called Bicycle Advocacy 2.0. It's working more effectively in four short years than the past four decades of 'avid cyclists' promoting cycling. The tipping point grows closer day by day.
This is the value of Cycle Chic.


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Associate Professor (on Sabbatical Leave)
Areas of Expertise: Renaissance drama and poetry; 17th-century women writers; Aphra Behn; Shakespeare; Print and manuscript cultures
Biography: Research Interests:Early modern drama and poetry, early modern women writers, Aphra Behn, Shakespeare performance history. …
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Top holiday destination: France0
In second place of Britain's top 10 favourite holiday destinations is France. The rivalry between France and Britain became once again very clear during the Rugby World Cup but now that is all behind us, here are ideas to explore la belle France.
Holiday destination 2: France
Paris Landmarks
If you enjoy Paris sightseeing, there are plenty of things to do in the gracious capital city of France. The Eiffeltower is a landmark you literally cannot miss when visiting Paris. Tour the Eiffeltower and have a peek behind the scenes with our special Paris tour.
At night enjoy the splendour of illuminated Paris safely from a coach, which will then drop you off at the infamous Moulin Rouge for an evening of glitz and glamour. Alternatively, see the city of light during an evening cycling tour with an English speaking guide. Cycle passed Paris highlights as the Notre Dame, The Louvre, the Eiffel Tower and the Champs Elysees. After the tour you will take a cruise on the Seine and sip some of France's excellent wine.
You also have to make time for a cultural trip to Versailles from Paris and admire the beauty of the Palace while you explore Versailles at leisure. Lastly for the romantics among you, we offer a private portraits in Paris tour, where a photographer will lead you through the historic Latin Quarter and make portraits of you and your loved one to remember this magical moment in Paris.
Nice and the French Riviera
People looking for milder climates should visit Nice in Southern France. Take a city tour of Nice and discover landmarks like the Promenade des Anglais, Old Town and Russian Orthodox Cathedral.
Take off from Nice and tour the French Riviera, where you will visit the most glamorous places on earth. Revel in the old glory of Monte Carlo, admire the beauty of Antibes and touch down in Cannes, known for its film festival.
Wine Tours in France
We also offer a few wine tours that wine connoisseurs might enjoy: take the wine road through Provence tour with tastings at Chateau Saint Martin and Chateau Font du Broc. Enjoy wine tasting tours in Bordeaux, the largest and most famous wine region in the world or you can take a wine tour in Lyon, which lies in the Beaujolais region.
In Avignon, the wine tour consists of tasting the most prestigious red wine in the Rhone valley in the winery founded in Chateauneuf-du-Pape. You can also explore the city St Remy where Vincent Van Gogh painted his Starry Night.
Cultural reference: Van Gogh's paintings and the Da Vinci Code
Vincent van Gogh used to live in the Provence and let the landscape inspire his paintings not only in St Remy but also Arles one of the bigger cities in France.
A Van Gogh tour from Marseilles is also available, and after visiting the landmarks you can participate in a regional olive oil tasting Of course France is also associated with great French food: the Belzier tour offers you seafood and wine of the Languedoc. Also in the Languedoc area, lies Rennes le Chateau, a medieval town and discover how the stories and the religious conspiracy theories influenced the story of The Da Vinci Code.
With its scope of possibilities for city break to beach holiday or culture weekend – no wonder that France stays a popular holiday destination for Britain.