text:
Process Development Jobs Still the Most...
Nothing Beats Immunoassays for Sensitivity, Specificity,...
Adapting to Evolving Business Environments Is...
Quadruple Helices Appear To Have Role...
Find out how Bio-Rad's Bio-Plex® suspension array system has contributed to research findings in Dr. Francis Spinale and Dr. Steven Kornblau's laboratories and may impact the screening and treatment of disorders like leukemia and heart disease.
Steven Kornblau, M.D., has been on the faculty at MD Anderson Cancer Center in Houston, Texas, for 20 years, where he divides his time between research into understanding leukemia and a clinical practice where he treats patients with the disease.
"Leukemic cells don't live in isolation; they're interacting with their environment within the bone marrow—they're interacting with their environment in terms of the blood that flows by them," says Dr. Kornblau.
Today, his research is revealing how the cytokines and chemokines that leukemic cells might be getting exposed to affect protein expression. The idea that researchers in his lab might find different cytokine and chemokine expression patterns within leukemic cells led to determining ways of profiling large numbers of cytokines.
Researchers in Dr. Kornblau's lab considered using ELISA kits for the chemokine and cytokine studies, but determined that this approach would require a significant amount of sample. There was also concern about the impact of batch effects on results.
"We were looking for something where we could analyze a lot of cytokines and chemokines simultaneously that also wouldn't require too much material," says Dr. Kornblau. "Around that time we saw that Bio-Rad was creating large cytokine kits, where you could look at numerous chemokines and cytokines simultaneously."
The lab used the Bio-Plex Pro™ human cytokine 27-plex assay to study a large panel of serum samples from acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS) patients (178 AML and 114 MDS samples). Because MDS is often considered to be "preleukemia," one of the questions to be addressed was whether MDS and AML exhibit similar or unique cytokine patterns.
"The first thing we found was that for both diseases, the pattern of expression was markedly different from the 19 normal controls that we had included," explains Dr. Kornblau. "The second thing we found was that for 24 of the 27 cytokines, there really wasn't a difference between their expression in MDS and their expression in AML."
Analysis of data generated in this study led to segregation of patient samples into eight different signatures. Identification of these signatures led to their correlation to different clinical leukemic features such as cytogenetics, outcome, and remission duration.
"We found to our surprise," remarks Dr. Kornblau, "that there tended to be a good, an intermediate, and an unfavorable group of signatures. These were independent of other established clinical features like cytogenetics, like age, like having an antecedent hematological disorder. We were surprised to see that the cytokine and chemokine profiles actually were prognostic on their own."
Dr. Kornblau explains that the results of this research set up the idea going forward that chemokine and cytokine patterns can be used to inform different therapies and enhance the ability of clinicians to affect leukemic cell growth or eliminate the resistance of those leukemic cells to different therapies already in use.
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While Zika continues to garner a lot of news coverage, a Mayo Clinic survey reveals that Americans believe the country's most significant healthcare challenge is cancer. Compared to other diseases, does the possibility of developing cancer worry you the most?
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text:
LG Premium Care
The LG Premium Care plan offers many valable benefits.Extend the protection on your LG Product for up to three years by purchasing an LG Premium Care Plan. Conditions apply.Act Now
Receive help on your LG product
Check out the latest information related to this product.
For the most accurate technical information regarding features, specifications, installation and operation of your LG product, please refer to the Owner's Manual and other documents available for this product.
Software upgrades include device drivers and firmware updates only for specific models. Check your owner's manual to determine if your product supports software upgrades.
Please check the Model List in the Reference section, paying special attention to the end (i.e. xxx-UA)
1. SmartShare PC SW(DLNA)
[PC requirement for installing LG SmartShareTM]
CPU Minimum spec : Intel Pentium4 2.0G uper / AMD Sempron 2000 uper
Recommended spec : Intel Pentium Dual Core uper / AMD Sempron 64x2 uper
RAM Minimum spec : 1GB uper
Recommended spec : 2GB uper
VGA Minimum spec : Memory 64MB, Resolution 1024*768 uper, Video card 16bit uper
Recommended spec : Memory 128MB, Resolution 1024*768 uper, Video card 16bit uper
HDD 200MB uper
OS Windows XP (Service pack 2 uper), Windows Vista, Windows 7, Windows 8
l Windows Media Player : 11.0.5721.5280 uper
Network 100MB Ethernet, Wireless Lan WLAN(IEEE 802.11g) uper
2. SmartShare PC SW(MediaLink)
To use MediaLink, the PC needs to have PLEX.
With Media Link, you can enjoy contents(Movies/Music) stored on PC on LG Smart TV with convenient UI.
[System requirements for installing PLEX]
- Minimum requirements
PC with at least 1.6 GHz Intel Core Duo Processor and Windows XP SP3, minimum 512 MB
of RAM
- Recommendations for HD Content transcoding (720p and 1080p)
PC with at least 2.4 GHz Intel Core Duo Processor and Windows XP SP3, minimum 2 GB of
Supports Windows XP, Vista and Windows 7
- Network requirements
ADSL/Cable/Wi-Fi Internet connection for media metadata output and update
Wired network: Ethernet network with 100 Base-T or 1000 Base-T
Wireless network: Recommends uncongested 802.11n & supports media play on wireless
mobile devices
[Applicable Model]
The LG Premium Care plan offers many valable benefits.Extend the protection on your LG Product for up to three years by purchasing an LG Premium Care Plan. Conditions apply.Act Now
You've come to the right place. Find the right accessories and parts for your LG products. Enjoy the reassurance of LG quality and convenience of complimentary shipping when buying directly from LG.com.Shop LG TV Accessories
Contact Us

subset: commoncrawl


text:
Friday, March 15, 2013
If you head towards the end of the Cooper River Bridge Thursday night, you might find a leprechaun's fortune there waiting for you.
On March 14, Catch the Leprechaun 5k participants will be competing for the mythical man's pot of gold at the race that is bringing residents of the Lowcountry together to celebrate St. Patrick's Day.
"We want the community to step away from their televisions to spend the night outside, having fun and getting some exercise," said race director Mike McKenna in a news release.
"We tried to add some excitement to the race by creating a festive atmosphere. We hope this will appeal to all the new runners and it will encourage them to make running part of their routine."
As an incentive to get people to come to the race, race orgnizers added more cash and prizes.
The fundraiser for Pattison's Academy increased the prize money to encourage the area's top runners to enter, but it is also introducing prizes that even a turtle with a limp can win. For the first time, a pot of gold will be given to the person with the best costume and there will also be a drawing for a class for five people at Exhale Pilates.
To learn more about theCatch the Leprechaun 5k, please visit www.CatchtheLeprechaun5K.com.
© 2016 Moultrie News an Evening Post Industries company. All Rights Reserved.
Registration on or use of this site constitutes acceptance of our Terms of Service, Privacy Policy and Parental Consent Form.


text:
This is an archival or historical document and may not reflect current policies or procedures.
May 2011
In This Issue:
Social Security Board of Trustees Report Released
The Social Security Board of Trustees released its annual report on the financial health of the Social Security Trust Funds. The report projected:
"The current Trustees Report again reflects what we have long known to be true we need changes to ensure the long-term solvency of Social Security and to restore younger workers' confidence in the program," said Michael J. Astrue, Commissioner of Social Security.
You can find the 2011 Trustees Report at www.socialsecurity.gov/OACT/TR/2011.
Social Security Budget Reduced
Congress provided us with $11.4 billion for our Fiscal Year (FY) 2011 administrative expenses$23 million below the enacted FY 2010 level and nearly $1 billion below the FY 2011 President's budget request.
Given the tight budget situation, we are continuing our SSA-wide hiring freeze with the exception of our hearings operation. We have had to cut most of the overtime, except for critical activities like helping people who come into our offices for service at the end of the day. Our field office and hearing office employees will no longer visit remote service sites; and we will not open the new teleservice center or eight new hearing offices as we had planned. We also have suspended issuing Social Security Statements. By making these very tough choices, we will be able to avoid furloughing our employees and will keep our doors open to the public in FY 2011.
Even though our budget has been cut, we remain focused on eliminating our hearings backlog by FY 2013. Our hearing receipts have been increasing, but we are hiring new judges and support staff over the next few months and, with adequate funding in FY 2012, expect to continue to make progress improving this important workload.
The number of employees we have determines the amount of work we can complete. We expect to lose about 3,500 employees this year and 4,400 in the next fiscal year if we continue to operate at an approximately level budget. We will do our best to serve the American people, and encourage everyone to use our online services at www.socialsecurity.gov
To learn more about Social Security's budget, visit www.socialsecurity.gov/budget.
Did you know that more than one out of five adults receiving Social Security have served in the U.S. military? Veterans and their families make up 35 percent of the beneficiary population.
Nearly 650,000 veterans under the age of 62 receive Social Security, and about 4.3 million veterans aged 75 or older draw Social Security benefits. You can find out more about the veteran and Social Security populations in the May issue of our research journal, Social Security Bulletin. While you're there, click "Subscribe to Updates" on the right side of the page to receive updates. Visit www.socialsecurity.gov/policy/docs/ssb/index.html.
A Handsome Gift for Dads Everywhere
Father's Day is right around the corner. Dads around the nation may get the usual gift: a necktie or new fishing lure. But there's one gift available that's even better. People all over the country can help their dads save nearly $4,000 a year on the cost of prescription drugs. You can encourage your clients to do the same and it won't cost a dime.
Extra Help available through Social Security could pay part of the monthly premiums, annual deductibles, and prescription co-payments. That Extra Help is worth an average of almost $4,000 a year.
To learn more about the Medicare prescription drug plans and special enrollment periods, visit www.medicare.gov or call 1-800-MEDICARE (1-800-633-4227; TTY 1-877-486-2048).
To learn more about the Extra Help from Social Security, visit www.socialsecurity.gov, where you also can find an easy-to-use online application.
Need a Baby Name or Answers to Your Social Security Questions? Use Your Mobile Device!
About to be a parent and you haven't had time to pick up a book to search for baby names? There's an app for that!
Use your iPhone, iPod Touch, or iPad to search the most popular baby names of the last 120 years using official Social Security data. Social Security's Baby Names Playroom allows you to browse names, search for a particular name, or choose the "surprise me" mode to randomly find names at the shake of your device. We even offer a trivia game and encourage you to use Twitter and Facebook to share your favorite baby names.
Got a Social Security question you need answered while you're on the go? Use our mobile-friendly FAQs page. Just go to www.socialsecurity.gov/faq from your mobile device.
Of course, you're welcome to visit our baby names and frequently asked questions pages from your computer or laptop -- at www.socialsecurity.gov/OACT/babynames/ and www.socialsecurity.gov/faq.
Subscribe to Social Security Update today and you'll always be in the know when it comes to Social Security news. All we need is your e-mail address.


text:
Musician's Friend Coupons and Promo Codes
Get the most recent Musician's Friend coupon or Musician's Friend promo code for rock bottom prices. Check the Stupid Deal of the Day, hot forum deals and discounts in categories including guitars, accessories, amps, bass, drums, keyboards, recording equipment, DJ gear and more. You can find a ukulele, orchestral instruments and gear for all of your rockin' needs. Every purchase comes with a 45-day complete satisfaction, lowest-price guarantee. At Musician's Friend, you can find Gibson, Fender, Epiphone, Taylor, and many more well known instrument brands. On their website, you can find a number for customer service, in which you can receive experts' help. There are more than 300 people located at their call center in Salt Lake City. You can also find a phone number to call for coupons. This company started in 1983 with a $5000 loan, and business has been exploding since then. They have earned a lot of awards, and also consider donation requests to organizations that facilitate music education. Musician's Friend prides themselves on value to help find the best possible deal with fast and free shipping, providing world class service, having over 85,000 products with more than 1.7 million items in stock, and by offering flexible ways to pay including financing options.


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"Let's talk about your dog. Now I love animals, everyone knows that I love animals. Your relationship with your dog is borderline," Ellen DeGeneres tells the Epic actress during a Thursday appearance on her talk show.
"Oh yeah, I know," responds Seyfried, 27. "He's with me right now. He's actually backstage. I really can't go many places without him."
No surprise here: Finn will soon be joining his mom on movie sets, too.
"I got him cast in his first movie," Seyfried reveals. "I can't really talk about his character, but it's going to shoot in September. I'm really excited about it. He's really excited about it."
Noting that the Les Misérables star is also a pet parent to cats, DeGeneres presses to find out why Finn has such a special place in Seyfried's heart.
"He cuddles with me and he listens to me, and he loves me and he looks at me all the time," says the starlet, as DeGeneres displays Twitter photos of the pair on the big screen behind her. She adds: "I got to stop doing selfies with him."


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on February 19, 2013 - 10:17 AM
Cuomo should end hidden energy tax
We have until Thursday to petition Gov. Andrew Cuomo to cut a hidden energy tax. It is called the Temporary State Energy and Utility Service Conservation Assessment. It may be called "NY State Assessment" on some utility bills. Our state legislators apparently think that it should be a permanent tax. They just extended it in Albany.
The tax was originally passed to raise money for the state during the financial crisis. The crisis is over. The hidden tax should end. I urge everyone to ask Cuomo to amend the 2013-14 Executive Budget recommendation and remove TED Part N.
When a government taxes energy, it is restricting productivity. Taxes on electricity and natural gas are slowing New York's recovery. The cost is high. TED Part N will cost all of us $236 million in 2014 and $2.8 billion over the next six years. Cuomo is a reasonable man who claims to be serious about reducing taxes. Let us all ask him to strike out TED Part N.
John Burt
President, Power Management Co.


text:
Average Ratings
2 out of 4 people recommended this car.
Consumer Reviews
Just had the right curves...
by Stratus Addict from Sterling VA | March 21, 2011
Maybe I am picky. I tend to look outside at my car through the living room window more than I spend driving them. If it does not have any style, why drive the car. We have so much choice in today's world. Oka, I like the curves on this car. But ever since 2000, the stratus has turned into another blob going down the road. Still not excited by the 200. I have had a 1995 2.4, I have a 1999 2.4 w/ 50k and a 1999 V6 w/ 108k miles on it. Both 2.4 needed new head jobs w/ pumps and time belts at 30-40k miles. 1995 held on till it started breaking engine mounts and then killed the transmission. Sold it at 90k with working AC. One thing about buying the same car, you can predict the problems. Fuse on the blower motor is one of things that are just annoying, check engine light always on here. V6 has been a great value since we picked it up with 29k for like $6k. Just now beginning to need stuff upgraded under the hood and will keep this one till it dies. All cars had gobs of power, but lousy mileage for the short runs to school. 18-22-28 Mileage on all of them. Hard to find these models any more, so will have to find a new choice.
Purchased a new car
Uses car for Just getting around
Does recommend this car
by Cheshire Cat from ClearH20 | September 26, 2009
This Car was a very fun car to drive handles great looks great and had a 162HP 2.5L V6 Enough power to get you into trouble but its not about looks its about it geting to point a to point b. I know most of the bad opinions are because people had a bad experience with a car. Heck, I don't like pontiacs anymore due to two the didn't work well with me. The best car I had was a Malibu that I destroyed in a car accident. Try it before you really knock it.
Purchased a new car
Uses car for Work
Does recommend this car
money pit
by brian from ohio | September 7, 2008
I've experienced similar problems as the first person who reviewed this car, my car is a 95 stratus ls 2.4 liter it's got 82k original miles on it so far i've completly rebuilt the transmision and had to put a new TCM(Transmion Control Module) on it after the fact, the transmision pan cracked and was leaking out fluid so that had to be replaced, The water pump just went and i also had to put a new timing belt in it luckly i caught it right after it started to wear out also needed a new idler pulley, so in general ive put probably 3k dollars more than this car is worth into it i just went to get an aligment and found out the struts and mounts are shot so now i'm just gonna drive it till it dies.
Purchased a new car
Uses car for N/A
Does not recommend this car
Piece of Junk
by Torreto from Texas | November 19, 2007
This Car was a very fun car to drive handles great looks great and had a 162HP 2.5L V6 Enough power to get you into trouble but its not about looks its about it geting to point a to point b and this car has gave nothing but problems i would wake up for work in the mornings and it wouldnt start later that day it would start and run perfect the transmission went out 3 times in 1 year distributor went out valve cover gasket leaking oil very bad oil pan leaking oil everywhere ac compressor locked up and broke the belt power stering pump and i only had it 2 years finally i gave up because the last thang was the timing belt jump and bent some valves that was costing me 2700 dollars so i sold it if u look at the car inside out the motor i kept up with everythang on it it was always clean you would look at it and thank its a great car but behind the beauty was a no good mitibishi motor. maybe i got one of the bad V6 stratuses but if i found a reliable v6 stratus i would but it in a heartbeat...
Purchased a new car
Uses car for N/A
Does not recommend this car
Featured Services for this Dodge Stratus
- Sell your current car quickly and easily on Cars.com.
- Not sure what auto repair should cost you? Use our price estimator.
- Get help with car repair now on Cars.com. Visit Repair & Care


text:
Top Definition
Runescape Off-Topic. The general term referring to the Off-Topic section of the forums. RSOT resembles a more intelligent and less porn-ridden version of /b/
Many regulars of RSOT know eachother. Some go off to create their own private websites.
Many regulars of RSOT know eachother. Some go off to create their own private websites.
I get on RSOT every weekend.
po Mod Fail Март 21, 2010
Trending Now
Can you define these popular missing words?
RSOT - Ride Safe Out There
RSOT - Ending quote- Ride Safe Out There. Cheers, MrFalloffalot
po MrFalloffalot(YouTube) Јун 5, 2016
Real Seal of Truth. It's the stickers they put on diplomas and notes of distinction that resemble the "wax seals" that were once melted onto official documents with the purpose of authenticating them.
RSOTs can often be found on fake documents photochopped by W. African internet scammers. A scambaiter laughing at their fake documents would often jokingly praise a scammer's RSOT, especially if it is the only thing on the faked certificate that doesn't contain spelling errors. As in "with an RSOT like that, this's gotta be real." Or "this RSOT just convinced me that he's a real barrister."
po KettleWhistle Август 3, 2008


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Indigenous Social Justice Association — Melbourne
Who we are and what we stand for
The Indigenous Social Justice Association — Melbourne (ISJA – Melb) was established in January 2005 to organise a Melbourne rally and march as part of a National Day of Action (NDA) to mark the first anniversary of the death of Kamilaroi teenager, TJ Hickey in Redfern, and to demand a fresh inquiry into the circumstances surrounding his death.
Those organising this NDA held consultations with interested members of the Victorian Aboriginal community. Participants in these consultations enthusiastically supported the proposal for a Melbourne rally to demand justice for TJ but asked that this not be a one off event but part of an ongoing effort to permanently stop Aboriginal deaths in custody.
ISJA – Melb is a grassroots, multi-racial activist group — open to both Indigenous and non-Indigenous people — which works collaboratively with others around the country campaigning to stop Indigenous deaths in custody. ISJA – Melb works in collaboration with those who have lost a loved one in custody and makes its decisions democratically with all meeting participants having an equal say.
ISJA — Melb primary objective is to stop Aboriginal deaths in custody and support Aboriginal peoples' quest for justice. However, recognises that the struggle to end Indigenous deaths in custody cannot be separated from the wider campaign for Indigenous rights. This is why we also work to advance campaigns to recognise the Sovereignty of Australia's many Indigenous nations and the negotiation of genuine treaties with these nations and why we oppose the Federal Government's intervention into NT Aboriginal communities.
ISJA — Melb calls for:
• A massive reduction in the rate in Indigenous imprisonment which is currently 13 times to the rate for non-Indigenous Australians.
• The full implementation of the recommendations of the Royal Commission into Aboriginal Deaths in Custody, including those Recommendations that both arrest and imprisonment be the sanctions of last resort.
• Because nearly 50% of the deaths in custody investigated by the RCIADIC were of the stolen generations, that we call for the full implementation of the recommendations of the Bringing Them Home report.
• No further increases in police powers – we oppose calls to further arm police with weapons such as tasers.
• The establishment of elected community based review boards with the full legal and legislative powers to investigate, discipline and charge police, prison and custodial health officers found to be involved in a death in custody, negligence or lack of duty of care to those they have a responsibility to and for. This is to include all juvenile justice areas.
• The provision by State and Federal Governments of adequate funding for Families who have lost a loved one in custody to meet at a state/territory level followed by a national meeting, as required, to allow their collective demands to be formulated, including suitable and adequate compensation.
ISJA – Melb also sees the connections between the treatment of Australia's Indigenous nations and other Indigenous people and oppressed nations around the globe and extend our solidarity whenever we can. We also note a pattern of institutionalised racism embedded within the capitalist law both in Australia and in other parts of the world. This is why we support the campaign to free political prisoners such as Lex Wotton, Mumia Abu-Jamal and Leonard Peltier.
ISJA – Melb believes that what we do makes a difference. We organise rallies, speak-outs, meeting, community education, petitions, benefits and other grassroots campaigning to highlight injustice and win a world where deaths in custody no longer occur. We do not place our faith in the system to deliver justice for Aboriginal people. Instead, we work to build an effective grassroots movement that cannot be ignored.
We welcome new people to get actively involved in ISJA - Melb. To be added to our e-list contact: email@example.com
Meetings held on the first Thursday of each month at Solidarity Salon, 580 Sydney Road, Brunswick. For further information call 9388-0062
Issued by Indigenous Social Justice Association — Melbourne
PO Box 308, Brunswick Vic 3056 AUSTRALIA. Phone: 03-9388-0062


text:
Your Government
City Calendar
City Code
City Directory
City Employment
Comprehensive Plan 2030
Featured Stories and Archives
Forms, Applications & Docs
Frequently Asked Questions
Legal Notices
Links Library
Maps Library
Sister Cities
Special Notices
ADA Compliance
The City of St. Augustine remains committed to providing accessibility to all and provides for handicapped accessible parking in the city. For a map of accessible parking locations, Click Here To notify the city regarding accessibility concerns contact Todd Grant, Public Works Deputy Director, Phn: 904.825.1040, Fax: 904.209.4286, Email: firstname.lastname@example.com. You may also write City of St. Augustine, P.O. Box 210, St. Augustine, FL 32085-0210.
Consumer Confidence Report
The City of St. Augustine remains committed to providing clean and safe drinking water. For the previous year's sampling results please click here. To notify the city regarding water treatment concerns contact: Patrick Timoney, Water Treatment Plant Supervisor, Phn: 904.825.1044, Fax: 904.823-2280, Email: firstname.lastname@example.com; or firstname.lastname@example.com, or write the City of St. Augustine, P.O. Box 210, St. Augustine, FL 32085-0210.


text:
Thanks for helping us sort this video!
Thanks for helping us associate the correct Pornstars to this video!
Помогите нам: эти порнозвезды присутствуют в этом видео?
Pornstar Name:
what's the title of the complite movie?
Anyone know that first girl?
blonde wanted a dp, he couldn't find her asshole.
I love how the really buff guy has such an awkwardly curved cock. He tried to do the DP, but I don`t think that other guy was having it. He found another slut though and shoved that curved cock deep inside her wet pussy.
i want to fuck that redhead girl
reminds me of fifa 98 xD love the song
seriously, the dude at 2:01 has a seriously curved cock....
My girlfriend goes to these shows all the time and loves them... now I know why! I won't stop her going again though!
Girls get my dic in offer just free of 13 inch
@ 2:01 there's obviously a problem with the hologram
goddd it almost feels sooo wrong watching this when my favourite band blur's song is playing in the backround :P
well.. i kind of feel sorry for this guys...
The attempted DP was pretty awkward. She's fucking the dude on the chair while that bozo is blindly rubbing his cock on her butt.
I'd love to take my wife to a club like this where the male strippers fuck the women there.
chimba de culiada las nenas divinas
first song name
It Looks like that AIDS are no Problem for the People
who sing second song?
girls aint pretty
i want to attend such a party too
the thing on ur mans head is fucking topclass
this turns me on so badly
@wtf hahaha
Same people in every cfnm video....must be a really exclusive party.... Bullshit, this ain't real!
lucky guy!
omgawd, me and my best friend went to one of these partys! i fucked a blond stripper who was the hottest man on the plannet! i luuuurrve having sex with him!


text:
Adirondack Cocktail Table
Add to your Wish List
Pine Wood. 39w x 26d x 15h". Available in the following colors: Natural, White, Hunter, Lime, Mint, Aqua, Caribbean Blue, Baby Blue, Rustic Red, Tractor Red, Flamingo, Butter, Canary Yellow, Olive Gray, and Black. Each color is available in either a solid finish or a washed finish. Please state your choice of color and finish in the comments section of your order form.
Customer Reviews
SORT BY > Newest > Oldest > Most Helpful > Highest Rating > Lowest Rating


text:
Go to http://www.isc.org/software/bind and download your desired version of BIND for Windows, e.g., version 9.4.2:
or version 9.7.3, which was released on February 15, 2011:
Unzip it.
Stop BIND service (PP nameserver service).
Copy the following set of unzipped files to the
Do not overwrite the files you already have; copy them somewhere for backup purposes.
BINDInstall.exe dig.exe dnssec-keygen.exe dnssec-signzone.exe host.exe named.exe named-checkconf.exe named-checkzone.exe named-compilezone.exe nslookup.exe nsupdate.exe rndc-confgen.exe rndc.exe libbind9.dll libeay32.dll bindevt.dll libdns.dll libisccc.dll libisccfg.dll libisc.dll liblwres.dll
Make sure that permissions are inherited from the parent folder
%plesk_dir%\dns\binand look like:
psaadm - allow read & execute psaserv - deny all psacln - deny all
Make sure that the Operational System has the version of Microsoft Visual C++ 2005 Redistributable Package installed that is equal to or higher than the version of the package shipped with the BIND distributive (the
vcredist_x86.exefile in the archive). The latest version of the package may obtained from this Microsoft article.
Start BIND service.


text:
Top Definition
an amazing person who is good at everything he does. most dylan jarvis's are atractive and are the life of a party because they love to get shwasted!
That Dylan Jarvis kid is totally fuckin that donkey! He is so cool! I wish I could be like him!
بواسطة dylanjarvis إبريل/نَيْسان 29, 2012
Trending Now
Can you define these popular missing words?


text:
"I appreciate that it is flat/matte print and not photo paper, which is more delicate, is shiny and shows any imperfections easier. It's a muted tone, but very beautiful alowing the pictures to pop."
"Nice quality paper. Herringbone print and neutral color provide a classy background that compliments your photos. Highly recommend! Overall presentation from Tiny Prints is exceptional. Even the box the cards arrived in was nice."
"Loved the value of these cards, still great quality you would expect from tinyprints but without a large price tag per card. Combine that with their amazingly timed sales making these cards super affordable! I wasn't expecting the absolute best but feel I got it with these cards. I loved this color and design background which I originally found on another higher priced card design but then stumbled across this one and was very pleased to get almost exactly the same items that caught my eye for a lower price. To top it all off, tinyprints shipped this order very quickly. I hadn't even collected all of my addresses when these arrived 3 days ahead of schedule - and I ordered economy free shipping! Once again tinyprints delivers what I wanted in a timely manner. They might not be the absolute cheapest option but they are the best!"
"I ordered a set of these photo cards and just received them. These cards exceeded my expectations. The paper quality is fantastic and the colors are vivid. They look much better than your typical card on photo paper."
"This card turned out great! I was surprised by the thickness and quality of the paper as I was expecting a photo paper card. Excellent design and the coated finish added a nice touch."
Copyright © 2004-2016 Shutterfly, Inc | Tiny Prints | Terms of Use. Designated trademarks and brands are the property of their respective owners.


text:
IMPORTANT: Please click "End Session" to clear your personal information. (Credit Card info is always hidden from view).End Session
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49 items
Men's Eddie's Favorite Flannel Classic Fit Shirt - Plaid$60.00-$70.00 $50.00-$60.00
Men's Treeline II Long-Sleeve Shirt$60.00-$70.00 $42.00-$49.00
Men's Wrinkle-Free Pinpoint Oxford Classic Fit Long-Sleeve Shirt - Seasonal Pattern$75.00-$85.00 $52.50-$59.50
Men's Contour Performance Crew$55.00 $41.25
Men's Eddie's Favorite Thermal Henley Shirt$45.00-$50.00 $33.75-$37.50
Men's Wrinkle-Free Pinpoint Oxford Relaxed Fit Long-Sleeve Shirt - Seasonal Pattern$75.00-$85.00 $52.50-$59.50
Men's Eddie's Favorite Flannel Classic Fit Shirt - Solid$60.00-$70.00 $50.00-$60.00
Men's Kachess 1/4-Zip Mock Shirt$60.00-$70.00 $45.00-$52.50
Men's Voyager II 1/4-Zip Pullover$60.00-$70.00 $45.00-$52.50
Men's Resolution Long-Sleeve T-Shirt$40.00-$45.00 $30.00-$33.75
Men's Legend Wash Henley Shirt$40.00-$45.00 $30.00-$33.75
Men's Eddie's Favorite Thermal Crew Shirt$40.00-$45.00 $30.00-$33.75
Men's Contour Long-Sleeve Henley Shirt$65.00-$75.00 $48.75-$56.25
Men's Wild River Lightweight Flannel Shirt$50.00-$55.00 $37.50-$41.25
Men's Signature Twill Classic Fit Long-Sleeve Shirt - Solid$45.00-$50.00 $31.50-$35.00
Men's Classic Signature Twill Long-Sleeve Shirt - Solid$50.00-$55.00 $37.50-$41.25
Men's Grifton Long-Sleeve Shirt - Solid$55.00-$60.00 $38.50-$42.00
Men's Traveler Long-Sleeve Crew$70.00-$80.00 $52.50-$60.00
Men's Exploration Long-Sleeve Shirt$70.00-$80.00 $52.50-$60.00
Men's Field Long-Sleeve Polo Shirt$35.00 $26.25
Men's Greenpoint Long-Sleeve Shirt$70.00-$80.00 $42.00-$48.00
Men's Grifton Long-Sleeve Shirt - Print$60.00 $42.00
Men's Palouse Long-Sleeve Shooting Shirt$70.00-$80.00 $49.00-$56.00
Men's Okanogan Hunting Shirt - Blaze$90.00-$100.00 $63.00-$70.00
Men's Wrinkle-Free Relaxed Fit Pinpoint Oxford Shirt - Solid Long-Sleeve$75.00 $52.50-$59.50
Men's Wrinkle-Free Classic FIt Pinpoint Oxford Shirt - Solid$75.00-$85.00 $52.50-$59.50
Men's Wrinkle-Free Classic Fit Pinpoint Oxford Shirt - Blues$75.00-$85.00 $52.50-$59.50


text:
Top Definition
a little hottie with a body. short with dark hair this girl is a frisky young tigger. with the looks to kill this girl is the next plastic struting her stuff down the hall.
damn that mela is hot, ohh shit son isn't she going out with that ghetto drew.
carl benchwacker가 작성 2005년 04월 04일 (월)
Trending Now
Can you define these popular missing words?
Nickname for Maltese people from the island of Malta in the Mediterranean, due to them saying "mela" in just about every sentence. Used to mean various different things such as "of course", "ok", and "alright"; or just a filler in a sentence instead of "umm". Often repeated before or after the english word of the exact same meaning.
Answer to question - "Of course, mela, alright"
"The bus is here, mela"
"The bus is here, mela"
Raemantis가 작성 2009년 04월 24일 (금)
<Italian> Mela
<English> Apple
<English> Apple
La mela = The apple
Italian_Speaker_1989가 작성 2004년 04월 26일 (월)
Cute asian girl with long black hair. Is fun to be around and is also a nerd when it comes down to school. She makes the funniest jokes and can make people laugh like no tomorrow. Mela's are amazing and they are easy to talk to and easy to get along!!!
That Mela is SOOOO smart
When Mela walked past me, I smiled.
That Mela is soooo cute!
Mela's hair is so silky
When Mela walked past me, I smiled.
That Mela is soooo cute!
Mela's hair is so silky
cutiecake.x3가 작성 2011년 06월 16일 (목)
Being in the Los Angeles area.
Yo where you at? Me La. Ohh you La. Shut UP.
Lamberto가 작성 2008년 03월 19일 (수)
Cute little asian with the cutest laugh in the world. She can make your day instantly. Smart and frisky.
TeddybearRawrr가 작성 2012년 01월 10일 (화)


text:
Friday, September 27, 2013
The Town of Summerville has partnered with Google to provide free Wi-Fi internet in the historic downtown area. The service is already live and available for public use.
Town government, community members and Google officials will gather to announce the news to the public and kick-off the service next week on Oct. 1 in the Town Hall courtyard at 2:30 p.m.
Residents, businesses and visitors alike will be able to access the service. Seven nodes, or access points, have been placed throughout the historic area and will provide coverage on Main Street, West Luke Avenue, Richardson Avenue and East 2nd South Street.
The service was made possible through a grant from Google, Mayor Bill Collins wrote in his column in the Journal Scene this week. The $32,254 grant includes the cost of the wireless hardware, maintenance and customer support for the first year, according to the FAQ document the Town released on its website.
The agreement will provide free Wi-Fi for three years. According to the document, the purpose of the grant was to "attract visitors, nurture businesses and promote the Lowcountry knowledge economy."
Google has also supported free Wi-Fi in other Lowcountry locations over the past few years such as Goose Creek and Charleston's Marion Square and Waterfront Park. The projects are a part of the company's larger nationwide campaign to bring free Wi-Fi to public places.
More information on the service is available through the website www.SummervilleFreeWiFi.com.
© 2016 The Journal Scene an Evening Post Industries company. All Rights Reserved.
Registration on or use of this site constitutes acceptance of our Terms of Service, Privacy Policy and Parental Consent Form.


text:
CulinaryValais specialities (fondues, Valais plate), large selection of salads (buffet and a la carte), hot and cold, pasta
DetailsLocated near the mountain station for the de L'Ours cable car and from Veysonnaz. Self-service and a la carte restaurant. Open for groups in the evening (on request).
Entertainment: Music group in the high season
Additional offer: Open for groups in the evening (on request), package price incl. ascent supports.
Altitude: 2,000 metres
Accessibility: Cable car, ski lift, cross-country ski trail, winter hiking trail, ski slopes, ski tour
Built: 1984
Last renovations: 2010
No. of seats: Over 100
No. of deck chairs: 20 on request
Overnight accommodation: No


text:
Greetings Internets,This is a story all about how we made Apple and everything they own, our bitch for life.Hello, good day, and how are you? Splendid! We're LulzSec, a small team of lulzy individuals who feel the drabness of the cyber community is a burden on what matters: fun. Considering fun is now restricted to Friday, where we look forward to the weekend, weekend, we have now taken it upon ourselves to spread fun, fun, fun, throughout the entire calender year.As you should know, The Lulz Boat stores vast amounts of booty; much of this booty we don't release as it's simply too shiny and/or delicious. As of late, certain inferior sailing boats have discovered flaws in the iCloud (the iCloudthegame.com), thinking themselves exciting and new.Too late. The Lulz Boat controls this ocean, chumps.Some weeks ago, we smashed into the iCloud with our heavy artillery Lulz Cannons and decided to switch to ninja mode. From our LFI entry point, we acquired command execution via local file inclusion of enemy fleet Apache vessel. We then found that the HTTPD had SSH auth keys, which let our ship SSH into other servers. See where this is going?We then switched to root ammunition rounds.And we rooted... and rooted... and rooted...After mapping their internal network and thoroughly pillaging all of their servers, we grabbed all their source code and database passwords, which we proceeded to shift silently back to our storage deck."It seems the glorious leader of LulzSec got arrested. Whois driving the boat?"
@BarackObama has just passed. The President is dead. A sad 4th of July, indeed. President Barack Obama is dead@BarackObama has just passed. Nearly 45 minutes ago, he was shot twice in the lower pelvic area and in the neck; shooter unknown. Bled out@BarackObama shot twice at a Ross' restaurant in Iowa while campaigning. RIP Obama, best regards to the Obama family.#ObamaDead, it's a sad 4th of July. RT to support the late president's family, and RIP. The shooter will be foundBREAKING NEWS: President @BarackObama assassinated, 2 gunshot wounds have proved too much. It's a sad 4th for #america. #obamadead RIPWe wish @joebiden the best of luck as our new President of the United States. In such a time of madness, there's light at the end of tunnel
"I would consider us to be close in relation [to Anonymous], 2 of the members of our group were members of Anonymous," said a representative of The Script Kiddies, who, for reasons that should be quite clear, asked to remain, yes, anonymous. "I was a member of Anonymous. We hope to be working with them soon.""We are looking to find information about corporations to assist with antisec. Fox News was selected because we figured their security would be just as much of a joke as their reporting. It will be a never ending battle.""The names change from time to time like LulzSec and Anonymous or Script Kiddies. But [there] will always be a group of people that need to stand up for everyone else and attempt to keep the government in balance with it's people. Without groups like Anonymous, what is there to prevent corruption?"
Today we are celebrating our country, honoring our troops, and enjoying a little BBQ. From all of us at #Obama2012, have a wonderful Fourth.
quote: I'm sure the original dissenters who laid in the foundation for the USA were originally brushed aside as mere "pests".
quote: No, not really. This is where I have to say that you talk tough, but really aren't.
quote: The original people who pushed for the American Revolution, were almost all land owners, some more wealthy than others, some had considerable status at the time. All of them were willing to risk death (literally) for the cause.
quote: LULSec is willing to do what, make a few anonymous Twitter posts? Steal some old couples retirement funds? Yeah great role models....


text:
Developers of DTC Genetic Testing Are...
LC-MS Gains Favor Due To the...
NSCLC is "Major Battlefield" as Merck,...
As Immunotherapy Revolutionizes the Cancer Treatment...
In August, U.S. Senator Michael Bennet (D-CO) introduced the Drug Safety and Accountability Act of 2010. This bill is designed to improve regulatory oversight of drug manufacturing facilities and improve related quality standards and monitoring.
With increased government scrutiny, it is not a coincidence that quality is the top-ranked criteria for CMO selection, according to findings from HighTech Business Decisions' "Biopharmaceutical Contract Manufacturing Report: Expanding Markets, New Capacities and Improved Performance" for which directors from 48 pharmaceutical and biotechnology companies and 29 biopharmaceutical CMOs were interviewed.
Biopharmaceutical contract manufacturers continue to dedicate resources to improve quality and efficiency to meet the increasing demands from their clients and regulatory organizations.
As a result of strict regulatory oversight, once a standard operating procedure is validated and yields drugs acceptable to the FDA or EMEA, companies are reluctant to make any process changes or incorporate innovations. In response to this situation, the FDA issued a draft guidance document, PAT—a Framework for Innovation Pharmaceutical Manufacturing and Quality Assurance. FDA hopes that this guidance will help pharmaceutical manufacturers design, develop, and implement efficient tools for use during product manufacture and quality assurance.
Many companies have followed the PAT guidelines and designed innovative quality improvements into their processes. For example, Boehringer Ingelheim (BI) developed the BI-Purification Excellence (BI-PurEx) strategy to shorten development time while improving process understanding during early development phases.
The strategy is designed around preferred process steps and takes advantage of a set of highly sensitive analytical tools and automated screening technologies to efficiently develop each unit operation in a downstream process.
According to Barbara Esch, director of global marketing and business development coordination, BI-PurEx has resulted in a "more lean development process to reduce timelines in early development. In addition, through the integration of analytical assays and RAPPTor® high-throughput screening, process knowledge is gained throughout process development to maintain a critical focus on future market supply."
Also following PAT guidelines, RecipharmCobra Biologics recently implemented new analytical approaches for monoclonal antibody development. RecipharmCobra successfully developed high-throughput platform methods for residual host cell protein, DNA, antibody titer, and antigen binding for early potency determination based on the Gyros™ system.
"These platform analytical methods are qualified so that they can be used upon verification under product-specific conditions for GMP release and for the stability testing of drug substances and drug products for early clinical trials," explained Christel Fenge, GM. "This has allowed RecipharmCobra to reduce effort and time lines for analytical development early on in projects. One of the benefits for the customer is obviously the reduced cost of development associated with bespoke analytical methods and lengthy manual procedures."
RecipharmCobra also has experience with PAT applied to QbD (quality by design), fostered by its history in product development. This expertise is of particular interest to biotechs, which RecipharmCobra actively supports in the appropriate design of product characterization studies to meet the requirements of the relevant clinical phase. "We consider this to be a competitive advantage and differentiator to other CMOs as we are able to offer a one-stop solution, from the gene of interest to GMP drug product accompanied by a comprehensive documentation and testing package," Fenge noted.
The Merck BioManufacturing Network, which is composed of two Merck business units—Diosynth Biotechnology and MSD Biologics—builds in QbD in biologics development and manufacture by way of high level of process understanding.
As Stephen Taylor, commercial director of MSD Biologics, explained, "during process development and laboratory process characterization (LPC) studies, the aim is to acquire a good understanding of each unit operation and define operating windows, to ensure acceptable and consistent product quality.
"If a high degree of process understanding is gained, and the process is consistently operated within the defined windows, then theoretically there should be less need to incorporate PAT." According to Taylor, this approach brings operational and delivery benefits to clients by enabling a relatively high throughput of different products.
PAT is also being used in process development and selected manufacturing campaigns at Merck. "During a typical fermentation, critical quality parameters such as pH, temperature, CO2 evolution, O2 uptake rate, and respiratory quotient are monitored in real time using probes and in-line mass spec analysis," Taylor commented. PAT has been implemented during downstream processing, though to a lesser extent "where real-time monitoring has been used to determine when process steps have progressed to an optimal level," he added.
CMC Icos Biologics has integrated analytical characterization of the protein produced during the clonal selection phase of cell-line development with its CHEF-1® expression platform, focusing on selection of clones producing the highest quality product in addition to selecting for productivity and viability.
Jenifer L. Wheat, vp of business development, said that "ensuring choice of a clone expressing protein that matches the specifically desired analytical profile is critical for second-generation processes and biosimilar development. Monoclonality is also assured through imaging of colony outgrowth with Genetix' CloneSelect, providing higher confidence levels in clonality than traditional limiting dilution cloning."
Meridian Life Science is actively evaluating and implementing PAT initiatives. Design control, environmental monitoring, process yield improvements, CAPA streamlining, risk management, and process mapping are a few of the initiatives being implemented.
"These processes are helping Meridian increase our competitiveness and fully meet the needs of our customers in domestic and international markets," commented Alan Rich, director of regulatory affairs and QA/QC. "They are allowing Meridian to shorten lead times for new product releases, reduce costs, minimize headcount, improve quality, and reduce scrap."
William Downey ([email protected]) is president, Cindy Liu is managing director, and Jennifer Hartigan is senior scientific director at HighTech Business Decisions.
William Downey ([email protected]) is president, Cindy Liu is managing director, and Jennifer Hartigan is senior scientific director at HighTech Business Decisions.
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Novum Pharma recently raised the price of an acne cream by over 3,900% in less than a year-and-a-half and Mylan increased price of EpiPen from $100 to $608 . Do you think pharmaceutical companies need to be subjected to price controls?
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400 Watt 14000K Metal Halide Bulb - Hamilton, Double Ended
400 Watt 14000K Metal Halide Bulb - Hamilton, Double Ended
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Accessories & Similar Items
400 Watt 14000K Metal Halide Bulb - Hamilton, Double Ended
Product Manuals & Documentation
The double-ended 14000K metal halide bulb offers excellent coloration and good intensity. It is crisp-white. It brings out the fluorescent pigments in corals nicely. Fluorescent supplementation is usually not necessary, but can be used for added intensity and to simulate dawn and dusk. An electronic ballast, magnetic pulse-start ballast or magnetic HQI ballast is required to ignite this bulb. It must also be housed inside a pendant. It cannot be used with simply a reflector in an open application as UV rays emitted by the bulb must first be filtered with a UV-proof lens. An excellent choice for reef tanks 22"–30" deep.
The Hamilton single-ended 14000K metal halide bulb offers excellent coloration and good intensity. It is crisp-white with a blue tint. It brings out the fluorescent pigments in corals nicely. Fluorescent supplementation is usually not necessary, but can be used for added intensity and to simulate dawn and dusk. This bulb will work with a standard magnetic ballast, magnetic pulse-start ballast or electronic ballast. An excellent choice for reef tanks up to 18" deep. on how the different Kelvin ratings appear and more information on metal halide bulbs.
Common questions/problems concerning metal halide lamps:
Metal halide lamps of the same kind are different colors?
Metal halide lamps operate by passing an electric arc through an arc tube that excites particles in the arc tube. When the metal particles reach an excited state they emit energy in the form of visible light. It takes 100 hours of operation before the metal particles stabilize and become a consistent color. All metal halides require 100 hours of operation before color and light output stabilize. All metal halides inherently have a slight color variation between individual lamps.
The metal halide lamp fires and then either burns dull or the arc extinguishes?
Usually the ballast and lamp are not receiving enough power. Metal halides pull a high current. Usually the problem is either there is too great a load on the circuit or the extension cords are of a small wire size and can`t handle the power needed by the ballast. Use only heavy duty extension cords and try running a ballast off a circuit from another part of the house.
Do I need a cover shield between the lamp and the aquarium?
Metal halide lamps produce a large amount of UV and also have a potential of exploding. The single ended metal halide lamps have an outer jacket which eliminates most of the UV. However, they have an inherent risk of exploding and UL requires metal halide lamps to be enclosed. On double ended lamps there is no UV shield. Double ended lamps must have a glass shield or major eye injuries including blindness may occur.
Can I operate a ballast and lamp together which are designed for different wattages?
Each wattage lamp and ballast are designed together for optimal performance and safety. If you over drive the lamp it may explode and shorten the life of the ballast and lamps. If you under drive the lamp it will also shorten the life of both components and also may explode. Do not mix different type wattages of lamps and ballasts.
NOTE: The bulb should be handled carefully. Using soft gloves is a good idea to keep finger prints off bulb. This is during installation and replacement.
Bulb Replacement Guide
Bulb Types
Life of Bulb*
Normal Output Fluorescent
6-12 months
Very High Output (VHO)
6-12 months
Power Compact (PC)
9-12 months
T5 High Output (T5HO)
9-18 months
Metal Halide
9-12 months
LED (non-moonlight)
~5 years (50,000 hours)
* Manufacturer Recommendations
Main Features
Product Manuals & Documentation
Manufacturer Info
Hamilton Technology Aquarium Supplies
Hamilton Technology is the leading manufacturer of high quality aquarium lighting offering customers the widest selection of metal halide, compact fluorescent and VHO lighting available today at the lowest prices. Their mission is to offer state-of-the-art lighting that meets high standards of quality, innovation and value. Hamilton Technology has served the lighting needs of both the professional and the hobbyist aquarist for more than sixteen years and is considered by many to be the choice of experts.
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Don't waste jobless training funds
July 3, 2013
Taxpayer-funded programs to help the unemployed find new jobs traditionally have been among the most inefficient, corrupt initiatives in government — and that is saying a lo....
have Dewine look at it now.If there is a problem it would save the taxpayers money.
2 Agrees | 0 Disagrees | Report Abuse »
Just another salem news opinion.
Since their against everything ,maybe they could offer a solution once in awhile !!
2 Agrees | 2 Disagrees | Report Abuse »
Thank you Salem News and bringing this to the attention of the taxpayers. To many times it is stuff like this that is created as programs that are not created benefit those that need it. A majority of the time it is only to keep Government employees employed and not on unemployment lines. That is the farce in America. It is ridiculous and Government just keeps growing and growing and growing and NOW the tax base keeps shrinking and shrinking and shrinking. It is a system that is working against itself. This is on both sides of the aisle. Whenever they need to lower the unemployment numbers, the politicians create more Government programs and employ Government workers. It is going to eventually kill this country. Imagine a scenario where we all WORK FOR GOVERNMENT.
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"Imagine a scenario where we all WORK FOR GOVERNMENT."
I agree it seems this where we are headed, but it has already been tried in the former USSR and it failed.
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This is the blog about Oracle Business Integration Design Patterns. Our team which is part of Business & Data Integrations Development Organization at oracle, focuses on providing technical and architectural guidance & support to Fusion Applications, AIA as well as Product Development teams across various Global Business Units on designing & building integrations. This blog focuses on discussing the different types of integration use cases we have come across and how the design patterns prescribed, could be used to implement similar use cases leveraging various components (BPEL, OSB, Mediator, OBR, BAM, BPM, CEP, WLS) available in Oracle SOA & BPM Suite.
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AuctionBytes posted an article called "IRS to Track Online Sellers' Payment Transactions Beginning Next Year" you might want to read.
The fact that the IRS is going to be scrutinizing online payments shouldn't come as a surprise to anyone. I'm actually surprised it hasn't happened yet. I'd welcome being able to receive official 1099s from Paypal to assist in my annual tax preparation. The proposed new form will be called a 1099-K, Merchant Card and Third-Party Payments. You can see a sample below.
Unfortunately, for those of us managing small online businesses, this new scrutiny is only going to apply to those with sales exceeding $20k and 200 transactions.
Perhaps Paypal will give the rest of us an option to receive reporting based on this new requirement. One can hope, right?
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I want to…
- Police accountability trends for 2015 in Portland. Find Auditor's Independent Police Review annual report here: https://t.co/ZojgxYRnY8
- We need an analyst for the Auditor's Independent Police Review. Apply July 18-July 29. More info: https://t.co/8K5ZW3MUnp
- Here's what's on our list to audit for next fiscal year: https://t.co/f4SGuPauR2
- Consumer payment card information is safer in City transactions. See our follow up to 2014 audit findings. https://t.co/XkNFDIj1c9
- Amid Record Revenue, Portland Mayor Charlie Hales Proposes Cuts to City Watchdog https://t.co/SOYfX1LHZT


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Microsoft actually built a multi-touch mouse before Apple; at CES last year Stephen Bathiche, the head of the Microsoft Applied Sciences team, told TechRadar how his team designed a capacitive mouse and announced their research prototype at a conference a month before Apple announced the Magic Mouse.
The Microsoft hardware team has taken another year to turn that prototype into a mouse they're happy with, collaborating with researchers in the Applied Sciences team and the innovation development team at Microsoft Research in Cambridge (many of whom worked on projects like Microsoft Surface).
Hrvoje Benko of the Applied Sciences group showed TechRadar a selection of the prototypes from the three years he's been working on the 'Mouse 2.0' project. (Benko is behind the Lightspace project that uses a camera and projector "to make any surface, any wall - any body part! - into a Surface.")
CONCEPTS: Five different ideas for Mouse 2.0 - FITR mouse, Touch Mouse, the articulated franken-mouse, the hemisphere mouse and the mouse that shines a laser on your desk
The idea was to combine the good old mouse - which has been around since the early 1960s without much change in the way you use it - with the multi-touch features of Microsoft Surface. You can touch, grip and gesture with your whole hand, but the mouse reduces all your dexterity to a single cursor and right-click.
The Mouse 2.0 concepts went through several different kinds of touch sensors. A curved mouse made from acrylic sheet and an infrared camera (using the Frustrated Internal Total Reflection technique Perceptive Pixel uses for touch screens where the touch of a finger is detected because it allows reflected internal light out of the surface layer) looked good but could only sense the tips of your fingers.
Putting a diffused illumination infrared camera in a half sphere produced an unusual shape that had too much internal reflection and while it made users more creative in the way they used gestures it also made their hands get tired.
An articulated mouse made from the innards of two mice bolted together, with knobs for two of your fingers sticking out at the front, was accurate and comfortable - but only allowed two-touch gestures.
One design with an infrared laser and camera detected your fingers touching the desk surface around the mouse, but only worked well if it was just the right size for your hand.
More like a mouse
In the end, the team picked a multi-touch mouse using a capacitive sensor, because that lets you have gestures without abandoning the familiar mouse shape (the sensor is small and you don't need to fit in a camera; it's not too expensive, either, because it's printed onto plastic using conductive ink).
"The benefits of the mouse are that it's comfortable and precise," Benko told us. "We didn't want to come up with something that meant people have to change the way they use the mouse. You can still point and click."
But when you click, it's not a button that's moving; it's the whole mouse (and that's more to give you feedback than to detect the click). "The whole surface of the mouse is a button so when you right-click and left-click it's really the same - but we detect where you click and that's what determines the click," he explained.
PROTOTYPES: Some of the many stages of designing the Touch Mouse, from the 3D printed (but fully working) first CAD prototype to the almost-finished wireless mouse. The diamond pattern is the multi-touch sensor - which is covered in later prototypes
Clicking and gesturing on the mouse surface is very comfortable thanks to the textured surface, which is a grid of tiny laser-etched dots. "This mouse will be used a lot", boasts Benko, "so we used laser etching; you cannot rub this off."
The mouse has a matte surface on purpose. "We spent a lot of time optimising the surface top coat. It's not glossy - try moving your fingers on a glossy surface for more than a few minutes; it gets really tiring," he points out.
And the dots are there for two reasons. "They showcase where the sensor is, and they make the surface a little bumpy, so if you have oily fingers you can still make the gestures because it has some tactile feel to it."
INSIDE: The multi-touch grid senses your fingers, the optical sensor works like any other mouse and the microswitch at the front is the mouse button
The shape of the mouse went through many different iterations and hundreds of protoypes, some with radically different designs; individual features that were popular with testers were combined into the final version. And the way that the touch surface on the mouse recognises gestures is based on how the hundreds of testers moved their fingers.
"We thought about how to define the gestures - move your finger this many millimetres up and you trigger the gestures. We decided to record a whole bunch of people doing them; we had folks with really giant hands, people with really small hands, male, female, left-handed, right-handed. We asked them to do things like 'put two fingers down and move up' and we used that to define how we recognise that gesture."
How many fingers make sense?
You scroll by dragging your fingers over the top surface but you can do more than scroll up and down; move your fingers from side to side and you scan scroll and pan across a window.
In a long document you can flick your finger up, down or across and then tap to stop scrolling when you get to the right page. Using two fingers to scroll controls your current window; move to fingers up to maximise a window or restore the previous size, two fingers down to minimise or restore a window - and two fingers to the side uses Aero Snap to fit to half the screen.
Use three fingers and you control all your windows; move three fingers up to open the revamped version of the task viewer in the IntelliPoint software, move three fingers down to minimise your windows and show the desktop.
"I'm a firm believer that the most dextrous finger on your hand is your thumb," jokes Benko - so you can swipe your thumb on the side of the mouse and move back and forward between web pages in the browser or slides in PowerPoint or images in Photo Gallery (it works in any app that has back and forward buttons).
TOUCHABLE: The grid of dots is laser etched into the Touch Mouse; the texture makes it easier to grip and less tiring to use
A little glowing indicator on screen shows you that you've used your thumb so you don't get confused (avoiding a problem that showed up in early testing when users sometimes didn't realise when their fingers were making a gesture) and this is a huge timesaver that immediately feels natural.
There aren't any gestures that use more fingers even though the mouse knows where they are. "We can see all five fingers", Benko explained, "but it's hard to keep even four fingers in place." The limitation is not what the mouse can detect but whether more complex gestures would be easy enough to use.
"We can actually detect 20 touch points," he told us, adding that his team wrote the underlying sensor code "and the actual underlying infrastructure is fairly similar to the code that's running in the Surface touch processing."
SIZE IS EVERYTHING: The gestures you can make on a mouse are limited by the size available - the Touch Mouse is big enough for most hands
The signal processing that the mouse does can encode lots of individual points on the touch surface at the same time but, as he put it, even though the touch surface goes almost to the very edge of the mouse "we have a real limitation with space and with your hand."
You can turn off gestures you don't use and switch the mouse to be left or right handed, but you can't make up your own gestures.
"We spent a lot of time optimising the gesture set so you can do these three different functions. Given the amount of time it took us to nail this experience," he suggests it might not be easy to design your own unique gesture that won't be mistaken for anything else. "You don't want to have the crosstalk problem: is it this gesture or is it that gesture?"
The future for the Touch Mouse
The team is thinking about more ways to use the multi-touch sensors, though. "We've thought about the authentication aspect," Benko told us enthusiastically; the way you move your fingers is often unique enough to identify you, so just gesturing on the mouse could be enough to log you in or load preferences for a different user if someone else uses your mouse.
"It would be really cool to do simple things - like we can totally detect handedness and we could switch the settings automatically. It would be really interesting - but at this point we're still nailing the basic experience. We want to come out with a great experience at launch."
Now that the Touch Mouse is almost done (it will be on sale in May), Benko's team is experimenting with what else they can do with multi-touch. "We've built some different mice with this type of sensor," he told TechRadar, mentioning one particularly intriguing idea we hope we get to see at CES 2012. "We've wrapped the capacitive surface around a pen and used it as a sensor."
Liked this? Then check out The idea that clicked: a history of the mouse
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Despite the fact that there's an army of Star Wars fans out there who are capable of growing hair on their faces, Star Wars The Clone Wars, the animated series that's heavy on super cute androids and digital caricatures of Yoda and co, is firmly aimed at boys aged six to 12. This is the reality of Star Wars. It's not designed for old fuddy duddies like you and me. It's designed for our sons and nephews. That much should have been clear the second Jar Jar Binks tripped up Liam Neeson on Naboo.
But that doesn't excuse how bad Star Wars The Clone Wars: Lightsaber Duels, last year's Wii-exclusive tie-in, turned out. It was bare bones, a boring one-on-one fighting game with tear-your-hair-out controls. It didn't matter what kind of Star Wars fan you were - for young or old the game was a bitter disappointment.
Still, somewhat predictably, it sold well enough to justify a sequel, Star Wars The Clone Wars: Republic Heroes, due out this September. This time, though, insists LucasArts associate producer Vince Kudirka, the game will be good. At Activision's pre-E3 London event he told us why.
"The big thing we wanted to change this year was to do a story game that pays off the show the best," he explains. "Fighting games, I mean it was good fun, it was great and I think it did a great job of bringing in all the different characters, but with this one you can have a plot that's based in the world of the show. We go to different locations that are featured in the show. We have some other characters. Cad Bane (mysterious bounty hunter) is a new character that showed up at the end of season one, he's featured prominently in our game. That I think is a big difference and a big strength of our game."
In fact, it's a completely different game. For a start it's being released on every platform under the sun, not just the Wii. It's not a one-on-one Dragonball Z-style fighter, either, but a full-on action game in the vein of Marvel Ultimate Alliance, that can be played co-operatively with up to two-players. And it's got a brand new storyline, too, penned by a show writer and designed to bridge the gap between seasons one and two of the animated series. Already it's clear this is something of a back to the drawing board effort.
You play as one of eight major Jedi from the series, Anakin Skywalker, Obi-Wan Kenobi, Mace Windu, Kit Fisto etc, or one of eight different Clone Troopers, including Clone Captain Rex. The Jedi gameplay is, as you'd imagine, full of lightsaber combat and simple combos. There's an area of effect stun, there's a Force Blast (which can be charged up and used to push enemies and environmental objects) and, providing depth, moves like Force Push can be integrated into lightsaber combos.
The big new feature for this game is what LucasArts calls "droids as toys". You can jump onto any enemy in the game, take it over and use its abilities. Anakin can, for example, leap on top of a droid, thrust his lightsaber down into its head and then steer it as if driving a mechanised ape, firing its lasers at anything and everything. One droid can be used to lay down mines. Another, called a Destroyer (like a rolling ball with a shield), can be jumped on and rode. We might not have seen that kind of madness in the films, but it's a damn sight more exciting than waving your wand and muttering "these aren't the droids you're looking for".


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Wednesday, November 6, 2013
Mount Pleasant resident, Terry Schildcrout, (center) along with her Los Angeles daughter, Jenifer Schildcrout, and her sister from Baltimore Md., Susan Kanow, (right) experienced an awe-inspiring and bonding "girls'" trip to Israel. They brought the Moultrie News along as they stood at the entrance to the tunnels under the Western Wall in Jerusalem.
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The Elkins Lions Club has announced it is sponsoring Erin Hohl so she can go to Leadership Camp at Camp Horseshoe this summer.
Hohl is a student at Elkins Middle School and an active member of the school's LEO Club. She attended an Elkins Lions Club meeting in March with her mother, Jennifer Hohl.
David Cooper was the guest speaker at that meeting, and he spoke to the club about programs at Camp Horseshoe.
Article Photos
Submitted photo
Erin Hohl, left, and David Cooper attend a recent Elkins Lions Club meeting. The club will sponsor Hohl so she can participate in Leadership Camp at Camp Horseshoe.
The Elkins Lions Club is proud to offer its support. Students come out of their Horseshoe week with changed attitudes, hope for the future, new perspectives on all they can be plus commitments to get involved helping back home.
More information about the Lions Club is available by contacting Verna Corley, president, at 304-636-7431, or at email@example.com.


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Top Definition
A member of a gang who mastrubates on the sides of other members legs without them knowing. This gained popularity in southern california in the past 5 years. They may also mastrubate in2 members hair, ears, nose or hands.
Dude I saw emilio side gangster that new guy.
από chachaddict 14 Απρίλιος 2009
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College of Public Affairs Honors Ceremony
- When:
- Location:
- Hilda and Michael Bogomolny Room, UB Student Center
- Description:
Join us as we celebrate excellence and accomplishment among our students and as we induct new members of Pi Alpha Alpha, Pi Sigma Alpha and Upsilon Phi Delta honor societies.
This event is by invitation only.
- Contact Name:
- Briana Clark
- Contact Email:
- firstname.lastname@example.com


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Source: Anandtech
quote: I dare you call the people up that you built a computer for that had an ATI card in it. They will probably give you a cold shoulder and do not care to give you the finger. A good business only starts if the same customers keeps coming back for more.
quote: I dare you say the same exact thing to my face because saying it online is completely different since it acts like a buffer for insecure people. I have problems with ATI and AMD software and graphics drivers. Other people have the same issues, so it is not my screw driver that is causing me problems.


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- 31% merino wool, 31% bamboo rayon, 32% stretch nylon, 6% spandex
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Top Definition
A term used to describe having sex with someone who is large or has less than desirable physical qualities. It was coined one night when a invitation was sent out to join a party with a "extra large" sorority. When considering to accept said invitation, a man we will simply call JJ calmly said "lets do it, lets tank the whale".
So i went to that girls house the other night and we started to get it on until her room mate walked in and totally saw me tanking the whale.
dari Thom Burney Sabtu, 03 November 2007
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Of the millions of people who are excited about the Duchess of Cambridge's pregnancy, few are as proud as the 2,000 residents of Bucklebury, the small English village where she grew up simply as Kate Middleton.
"Tons of people walked in here last night, and we cracked open a few bottles of champagne. We had a bit of a party, that's for sure," John Haley, the landlord of The Old Boot Inn, tells PEOPLE.
That the West Berkshire village's most famous daughter is expecting a baby who could one day be king or queen is amazing enough. But the townspeople are also thrilled for the family on a personal level.
"Everyone in the area is really happy about the news and really pleased for Kate and William," said Haley, who was a guest at the couple's wedding.
"She will be a great mother," he said. "She is very caring and an absolute natural with children. It's great for her parents, too. It is their first grandchild, and they will love it to death."
"It is such a shame that she is in hospital with morning sickness. That's horrible," said Bucklebury resident Wynne Frankum.
"When the baby's born I'm sure there will be a few toasts raised in the local pubs," she added. "The whole village will want to celebrate once it safely arrives."
Another resident, Colin Morris, predicted a party atmosphere at the regularly scheduled village meeting this Thursday at The Bladebone Inn. "I have absolutely no doubt that there will be a huge number of glasses raised to the good health of Kate and William and their future son or daughter," he said.
"How can you be anything else other than pleased? They are such a lovely couple, and such a lovely family as well."
Meanwhile in London, many of William and Kate's closest friends and loved ones – including his cousins Princesses Beatrice and Eugenie – were on hand to hear the young voices of the African Children's Choir at a holiday concert at Chelsea's St. Luke's Church. The musical performance included a very fitting tune for the day the royal couple made their thrilling announcement: "Oh Happy Day."
Guests at the annual event, which benefits the Henry van Straubenzee Memorial Fund (of which William and brother Prince Harry are patrons), were buzzing about the happy news that Kate is expecting.
"William will be the most wonderful father," one friend said.
For much more on the royal pregnancy, including the couple's plans for a nanny, baby names and royal maternity fashions through the years, pick up this week's PEOPLE, on newsstands Friday
Reporting by PHIL BOUCHER and SIMON PERRY
Bucklebury Village, Kate's Hometown, Thrilled About Pregnancy
Samir Hussein/WireImage