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|Cake Decorating
Bake and decorate scrumptious cupcakes every time with Trophy Cupcakes owner Jennifer Shea. Make your cupcakes moist and flavorful with fruit layers, such as caramelized pineapple or a blueberry reduction. Create s'mores cupcakes with graham cracker crusts, luscious lemon cupcakes with shortbread cookie crusts and even blueberry pie cupcakes bursting with bright flavor. Fill luscious lemon meringue cupcakes with lemon curd, and chocolate cupcakes with lavender pastry cream. Whip up Trophy's famous buttercream, and use it to frost your cupcakes by hand, roll your cupcakes in sprinkles and decorate them with perfectly piped swirls. Plus, amaze your clients with hi-hat cupcakes, lavender crème brûlée cupcakes and more. Deliver incredible cupcakes that make sweet dreams come true.
Meet your instructor, baker and cupcake shop owner Jennifer Shea, and get started baking the perfect cupcake! Jennifer will walk you through her famous vanilla cupcake recipe, pointing out proper technique and pitfalls along the way. You'll gain invaluable tips not only for mixing your batter, but for portioning and baking too! Never again will your cupcakes be tough, dry or underdone!
Take your cupcakes to the next level by adding real fruit flavor. Learn three different methods for adding fruit: mashed into the batter to make moist banana cupcakes, caramelized and layered on the bottom to make delicious pi�a colada pineapple cupcakes or cooked into a berry compote using fresh or frozen berries to capture the taste of summer!
Create cupcakes with crunch as you learn three different crusts to pair with your baked sweets. Learn the importance of and secrets to parbaking as you create a sweet graham cracker crust, a tender shortbread crust and a flaky pie crust. Pick up shortcuts for adding a textured base layer, even when you're short on time! Then, learn how much batter to add before baking your crusts and cupcakes to perfection.
Discover delicious, sophisticated fillings as you make a mouth-watering caramel, a sweet and tart lemon curd and a refined lavender pastry cream. Master techniques for cooking sugar, tempering eggs and creating a silky-smooth custard. Then, Jennifer demonstrates four different ways to hollow out and fill a cupcake, all using tools you may already own!
Master Trophy Cupcake's delicious signature buttercream. Learn how properly whip it up into a fluffy "cloud," as well as how to color and store buttercream if you're making it in advance. Finally, explore the delicious flavor variations you can create by adding extracts, fresh vanilla beans or even melted chocolate!
Learn several easy methods for achieving professional-looking results as Jennifer demonstrates how to frost your cupcakes by hand or using a pastry tip. Learn how to edge your cupcakes with sanding sugar or sprinkles, how to make domed cupcakes by hand or by rolling in sprinkles and how to tint sanding sugar any color you can image. Then, gain confidence using a piping tip to create low and high swirls as well as rosettes and ruffles!
Delve into advanced decorating techniques as you learn how to toast meringue swirls and make truly creative hi-hat cupcakes topped with a swirl of silky meringue and dipped in rich chocolate ganache. You'll learn the proper method as Jennifer shares her tips and advice for keeping your hi-hats in place. Then, learn Jennifer's own method for making cr�me br�l�e cupcakes, complete with a baked custard layer topped with crisp caramelized sugar!
"Cannot thank you enough! I love, love, love ... the assortment of classes, as well as the fact that I can watch the lessons at my own pace, the instructions, the ability to write myself notes, etc. I also love the fact that the classes are for life! Thank you again for such a fantastic and wonderful site for just about everything I love to do!"
Sierra Foothills, CA


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Top Definition
Shore town in South Jersey in Cape May county. Popular vacation spot. Has many hotels, two miles of boardwalk with a few amusement parks, and a very annoying tram system that rides up and down the board.
Wildwood basically refers to these four towns: Wildwood, Wildwood Crest, North Wildwood, and West Wildwood.
Wildwood basically refers to these four towns: Wildwood, Wildwood Crest, North Wildwood, and West Wildwood.
As I was walking down the Wildwood boardwalk, the tram came up behind me and the old lady pulled the trigger to make the nasally, pre-recorded woman say "Watch the tram car, please. Watch the tram car, please."
de DarkDan 28 Ianuarie 2004
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a shore point on the jersey shore that has the best boardwalk one could ever set eyes on. seperated into four main parts, wildwood is located on a small isand called five mile island. although, more ghetto than ocean city or sea isle, wildwood, is a good time for everyone. most vistors to wildwood come from the philadelphia area. and no trip to wildwood, is complete without a trip to groffs restaruant.
I've benn going to wildwood ever summer since i was born, and it only gets better.
de mwphilly 16 Ianuarie 2007
Wildwood is an island located in New Jersey. It has a lot more bars, attractions, a 2 mile boardwalk, and a long beach. People from Philadelphia tend to be the bigger population of the island, unlike Sea Isle and Ocean City which are populated by suburban families. It's a great time for the family but if you're a regular, tourists are very annoying. They tend to mistake the foot washer for a bathing and changing station. During senior week is the worst time of year for Wildwoodians due to, well,SENIORS. Though it may have a SLIGHTLY dirtier beach, it's still pretty clean for the most part. The comparisons for this and Sea Isle and Ocean City is Isle and City are cleaner with nicer neighborhoods, but with hardly anything to do. Basically, if you like organised and sound suburbs with a great beach, go to Ocean City and Sea Isle. If you like a nicer version of a major city with a LOT to do with a nice beach, choose Wildwood.
Girl 1: Hey, you wanna go to Sea Isle with me?
Girl 2: Nah, I'm going to Wildwood. There's more to do any way.
Girl: Oh ok.
Girl 2: Nah, I'm going to Wildwood. There's more to do any way.
Girl: Oh ok.
de Marmarjr 10 August 2012
A mixed drink involving a Bud Light Lime and a portion of vodka.
Hey cupcake, go fix Uncle Seth a wildwood.
de Banana Grabber 10 Decembrie 2011
Wildwood: An awesome school where you can ditch classes and not get in trouble, where rich kids and celebrities' kids go. A school full of potheads where the teachers are crazy and no one cares if they fail every class. Also known as Wildweed to other private schools. Where there are no grades (you either exceed, meet, approach or Does not meet) and if you get exceeds you are thought of as a nerd. We hardly have any. Where getting Does not meet is fine and no one minds. Where everyone has a clique and middle schoolers go to big fancy parties and get drunk on sugar and dance all night. Where at parties all the girls wear strapless dresses and the guys take off their shirts to get tattoos. Where if you ask someone out the whole school will know within ten minutes. Where everyone has an iPhone 4s and a MacBook pro. Where everyone watches R rated movies and stays up in their bed watching TV all night long. Where untalented, rich, weed-smoking kids go. You should come to Wildwood its really fun!!!!!!!!!!!!!!!!!
Really? you go to wildwood? Awesome!!!!!!!! I wish my parents would send me there!
de iamamazingeveryonesoloveme! 10 Iunie 2012
1. A beach-town located in New Jersey
2. A town full of rambunxious horney teens trying to get laid
3. a hard-on that just can not be tamed
2. A town full of rambunxious horney teens trying to get laid
3. a hard-on that just can not be tamed
1. Wanna go to Wildwood for senior week? Hellz no!
2. This thailand whore house reminds me of an all-girl Wildwood.
3. uhhh, teacher, i cant come get the paper at the moment. -WHY NOT, BILLY?- uhh, i got wildwood -HAHA! GO TO THE OFFICE! HA!-
2. This thailand whore house reminds me of an all-girl Wildwood.
3. uhhh, teacher, i cant come get the paper at the moment. -WHY NOT, BILLY?- uhh, i got wildwood -HAHA! GO TO THE OFFICE! HA!-
de Franklin Delano Roosevelt 13 Decembrie 2004
The awesomest school in the world and the kids there don't care if people call them spoiled and rich and obnoxious (which they are NOT) because they know that, "so what if my dad is famous?" Wildwood teaches kids to be themselves and to not care about what people say about them. Wildwood grades so you don't feel obligated to get A's, just to meet the expectations, or even approach is good enough. Wildwood understands that everyone learns at their own pace. Wildwood is the best school you could possibly go to.
Oh my gosh, did you hear?! SHE GOES TO WILDWOOD!!!!! THAT AWESOME SCHOOL!!!!!!
de malibugrl 16 Martie 2011

subset: commoncrawl


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Top Definition
A type of urban camouflage. Dressing like a homeless person to discourage attention from normal people. Usually achieved by wearing tattered or dirty clothes and, (for men) not shaving for two or three days.
"You probably didn't see me there, I've got my bumouflage on"
ALT154_Jeevus tarafından 6 Kasım 2011, Pazar
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The Arkansas Children's Hospital Foundation announced Tuesday that the Bobby Petrino Charity Golf Classic was cancelled.
After consulting with the Petrino family, foundation officials said they had no choice but to cancel the June 18 golf tournament intended to benefit Arkansas Children's Hospital.
According to the foundation, Petrino apologized for any inconvenience the cancellation caused.
Arkansas Children's Hospital and the Foundation said they are grateful for the personal support of the Petrino family.


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National Alliance on Mental Illness
page printed from http://www2.nami.org/
(800) 950-NAMI; email@example.com
Stigma Stands as a Hurdle for Teens
By Zachary Culler, NAMI Media Relations Intern
In a recent article, researchers at Case Western Reserve University called for more exhaustive measures to gauge mental illness stigma in adolescents.
The authors of the article, which appeared in the Journal of Nursing Measurement, acknowledged rampant stigma surrounding mental health treatment among adolescents.
"Millions of young people do not receive mental health treatment every year. There are modifiable barriers to treatment, with an important barrier being stigma," says Melissa Pinto, one of the authors. "Working to achieve a supportive social culture toward mental health, by removing stigma, will hopefully result in more young people receiving mental health treatment earlier in the course of illness."
Pinto admitted that experts must better understand the nature of adolescent stigma before they can effectively combat it. Due to a scarcity of meaningful research on the topic, experts lack concrete metrics and data to explain the phenomenon.
"We need to find a reliable and valid way to measure the presence of stigma associated with mental illness among adolescents," Pinto explained in a news release.
The researchers used an existing measure, the Revised Attribution Questionnaire, to test its validity and reliability among 210 high school students in the southern United States. While they deemed the self-report survey valid and reliable for that sample, the researchers advocated the need to study more diverse age groups throughout the country in order to attain a broader understanding of adolescent stigma.
"I hope that this study serves as a foundation to build on the science in this area," Pinto says. "Peer culture is strong during the teen years, and mental disorders often first appear at this same time. It's important that we tackle this problem during this period of development."
While NAMI cannot do much to remedy the deficiencies of research institutions, its Child and Adolescent Action Center (CAAC) works to alleviate such stigma in teens and young adults. Most notably, NAMI hosts StrengthOfUs.Org, a social networking site that provides community and resources for youth living with mental illnesses. The CAAC plans to re-launch this resource in the coming months, possibly involving the introduction of an all-youth blog. StrengthOfUs.Org also fights stigma by offering educational support to loved ones of youth living with mental disorders.
In addition to these evergreen resources, the CAAC also works to host youth-targeted programs, such as Ending the Silence, at the state and local levels.
"It's not only important for young people to understand what early-onset mental illness is, but also what it isn't," explains CAAC Director Darcy Gruttadaro. "We understand that we have to convey those messages online, in print, and in person."


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Carfax vehicle history reports available with every pre-owned vehicle.
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The professionals in our Chrysler, Dodge, Jeep, RAM and Fiat finance department are skilled in the ways of auto loans, with options and incentives geared to your unique needs. We'll sit with you individually in order to identify the most important aspects of your current financial situation. That way, we can tailor solutions to you specifically. With Schlossmann Dodge City of Milwaukee, your chosen car can be exciting and affordable.
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on December 4, 2012 - 12:01 AM
Those Egyptians weren't kidding. When they crowded Tahrir Square in Cairo last year demanding the ouster of President Hosni Mubarak, they weren't asking for anybody but him. That's what new President Mohammed Morsi is discovering as the throngs return to the famous square protesting his power grab.
Apparently, Egyptians want an honest and democratic government and they are willing to put themselves at risk to get it.
Morsi last week issued a series of edicts that claimed power over the nation's judiciary, the last branch of Egyptian government he does not control. The response was immediate, as anger mounted on the plausible belief that Morsi and his Muslim Brotherhood used their election victories to monopolize power, marginalize opponents and issue a new Islamist constitution. Meanwhile, they have done nothing to resolve the nation's economic and security problems.
"Power has exposed the Brotherhood," said Laila Salah, a housewife in the Tahrir Square protest. "We discovered their true face."
Indeed, they did. Morsi and the rest of the Muslim Brotherhood are exposed as just another gang of ideologues intent on having it their way, whatever their countrymen want. If Morsi thought it would be easy, though, both the judiciary, which has called a strike, and especially the Egyptians protesting in Cairo and elsewhere, are sending a different message.
It's a heartening sign that Egypt won't easily slide back into autocracy. Whether it is enough is hard to tell, but the fact is that no one but Egyptians, themselves, are likely to be able to prevent it. This is their fight, and they are stepping up to it.
The Brotherhood, meanwhile, insists that it will not back down and that if protesters can muster 100,000 or 200,000 people, supporters of Morsi and the Brotherhood will overwhelm them with "millions" in their support. Bluff? Time will tell.
Meanwhile, the new uprising in Egypt should not go unnoticed in Libya, where the new government remains unstable, or in Syria, where rebels are trying to dislodge the brutal government of Bashar Assad. People do not want to risk their lives only to find out that the new boss is just like the old boss.
Or as Laila Salah put it: It's like a wife whose husband was beating her until one day she divorces him and becomes free. If she remarries, she'll never accept another day of abuse.
No one should, in Egypt, in Libya, in Syria or anywhere else.


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Wall Street Decline Takes Its Toll...
As Immunotherapy Revolutionizes the Cancer Treatment...
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Receptos agreed to license a humanized anti-interleukin-13 (IL-13) antibody from AbbVie, the branded-drug developer spun off earlier this year from Abbott, with an option to co-develop the drug following a Phase II proof-of-concept trial. Financial terms were not disclosed.
Receptos, a San Diego developer of drugs for immune and metabolic diseases, said it plans to conduct a Phase II study intended to demonstrate proof-of-concept of the antibody RPC4046 in eosinophilic esophagitis (EoE), an FDA-designated orphan disease indication.
AbbVie holds an exclusive option to enter into a global co-development collaboration for RPC4046 with Receptos following results of the planned Phase II study and regulatory discussions with FDA. Under co-development, the companies would equally share global costs of the Phase III clinical program and future development.
Receptos would retain a right to co-promote RPC4046 and share equally in profits in the U.S. Outside of the U.S., however, AbbVie would hold sole commercial rights and Receptos would be eligible for undisclosed double-digit royalties on net sales.
Under the collaboration, additional indications may be pursued. The mechanism of action has been shown to have potential in various immunological and allergic disorders, Receptos said in a statement.
"We believe that AbbVie's exceptional track record in immunology will be a strong asset in this collaboration," Faheem Hasnain, Receptos' president and CEO, said in a statement.
AbbVie's immunology pipeline is anchored by Humira, which has either submitted or is pursuing Phase III trials for indications that include the chronic skin disease hidradenitis suppurativa; peripheral spondyloarthritis, an arthritis-causing disease which affects mainly the arms and legs; uveitis, inflammation of the eye's uvea; and two U.S. indications: axial spondyloarthritis, another arthritis-causing disease affecting mainly the spine and pelvic joints; and pediatric Crohn's disease.
Last month, AbbVie announced that pediatric Crohn's patients aged 6–17 taking Humira in the Phase III IMAgINE-1 trial experienced a significant improvement in select measures of health-related quality of life at 12 weeks.
Humira is the most successful of the branded drugs AbbVie inherited from Abbott, and was last year's top-selling drug according to GEN's recently-published list of Top 20 Best Selling Drugs of 2012, with $9.265 billion in sales in 2012, up 19.3% from $7.932 billion in 2011. The drug is approved for numerous indications, including moderate to severe rheumatoid arthritis, moderate to severe chronic plaque psoriasis, moderate to severe Crohn's disease; moderate to severe ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and moderate to severe polyarticular juvenile idiopathic arthritis.
The AbbVie immunology pipeline also includes two Phase II drug candidates—BT-061 for rheumatoid arthritis (RA) and psoriasis, and GLPG0634, also for RA.
AbbVie completed a first-in-human Phase I study of RPC4046, demonstrating that it was well tolerated in healthy subjects as well as in patients with mild to moderate persistent asthma, and supports both single dose IV administration and multiple subcutaneous doses.
Should AbbVie pass on exercising its co-development option for RPC4046, Receptos said, it would obtain a worldwide exclusive commercial license to all indications for the antibody.
Immunology is one of five disease areas identified by AbbVie for future activity and growth; the others were HCV, oncology, renal disease, and Alzheimer's disease.
Receptos is also focused on immunology. Its lead drug development program, RPC1063, is an oral, once-daily modulator of the sphingosine 1-phosphate 1 receptor (S1P1R) pathway, a G protein-coupled receptor (GPCR) target for relapsing multiple sclerosis (RMS) and inflammatory bowel disease. RPC1063 is enrolling patients into the randomized Phase II portion of a Phase II/III study examining the efficacy of RPC1063 in RMS and a randomized Phase II study examining the efficacy of RPC1063 in ulcerative colitis.
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The first town of any significance south of Muscat, QURIYAT lies some 80km from the capital, a 45-minute drive from Ruwi along a fast and relatively empty new stretch of dual carriageway which weaves between the craggy foothills of the Eastern Hajar. Quriyat had the dubious honour of being one of the first towns in Oman to experience the destructive attentions of the Portuguese fleet under Afonso de Albuquerque. Albuquerque's soldiers attacked the town in August 1508, setting it ablaze and massacring its inhabitants – captives, it is said, had their noses and ears cut off, a popular Portuguese way of discouraging further resistance to their rapacious rule.
The town centre – a modest huddle of buildings and a low-key souk – lies around 7km off the coastal highway. The principal attraction is Quriyat's fort, which sits right in the middle of town, on your left as you drive in. Unfortunately, like so many other forts in Oman, it was closed at the time of writing for renovation – long overdue, judging by the crumbling exterior plasterwork and general air of dilapidation. In the meantime, you can still admire the fine old wooden entrance door flanked by two rusty cannon and the shuttered ground-floor windows which ring the building on three sides, suggesting that domesticity, rather than defence, was formerly the principal concern.
Continue along the road past the fort and a large mangrove swamp to reach the town's pretty seafront corniche, at the end of which is the harbour, with boats drawn up on surrounding sands overlooked by a round watchtower sitting proudly on the headland above.


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We had flooding from all the storms here, tornado warnings, more flooding. Hubby whipped up a solution to the problem with our basement and we have had no more water coming in the house, Praise God! I am still recovering from an emotionally draining day yesterday. It's not something I feel like blogging about, but some of you can probably tell I am just not myself lately. I should have been focusing on Carter starting his very first day of kindergarten, but my day was just cloudy. I am glad it is over and today is a brand new day.
Carter wanted to have lunch immediately after breakfast today because he goes to Kindergarten right after lunch. He is made for school. Last night at Back To School night, Carter's teacher told us "He sure is a wealth of knowledge with wonderful information!" She said it quite delighted. I told her I almost sent a note in his backpack to warn her of that. He is one of a kind.
He couldn't get on the bus fast enough when it came yesterday, so I didn't get a good picture. I decided to drive to the school so that I could capture him getting off the bus to go into class. This picture just makes me happy. He didn't even stop to say hi- ran right into class. He saw his name immediately, sat in his seat, and started on his work. It was his very first day but he looked like a pro. I know that much of the behavior that our children exhibit is learned from the parents, but I do think that I am learning something new about myself because of them every day.
I've also felt frustrated lately because I am not able to read everyone's blogs as I'd like, and comment, and participate in more of your fun memes and contests and such. I try as much as I can, but often I'll get a moment to sit at the computer and then realize that the playroom really needs to be vacuumed. And on the way to get the vacuum I notice the dishes in the sink. So I get those things done and then have something else to tend to. And lately by evening, I am just too tired to even think about turning on the computer. Then when I do get a chance to catch up, I see that I've missed you having your baby last week, or you having a really fun contest, or you just making a really good point about life. I hate missing out on these things!
I think learning to keep a balance between my real life and my blog life is a constant process. But, I do ask that if you have something big and important that you've just posted about or that is going on in your lives, please email me or comment here to let me know. I hate missing out!
So, to end this on an up... I get a girls night out tonight. My neighbor is having a jewelry party and it will be nice to get out- even if it is just next door.


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We had plenty of questions last night from viewers of "The Cutting Edge: Attacking Heart Disease." Dr. Sahil Parikh and Dr. Arie Blitz from University Hospitals Case Medical Center in Cleveland were answering viewers' questions throughout the broadcasts.
Dr. Parikh specializes in cardiovascular medicine and attended medical school at Johns Hopkins in Baltimore. He later worked at Brigham & Women's Hospital and Massachusetts General Hospital before coming to Cleveland's University Hospitals.
Dr. Arie Blitz is the director of the Heart Transplantation and Mechanical Circulatory Assistance at University Hospitals Case Medical Center. He attended the Albert Einstein College of Medicine in New York. Dr. Blitz implanted the first Jarvik Heart Pump used at University Hospitals and has also researched children's cardiac surgery.
Q: Is coffee bad for the heart?
A: The short answer is no. Some people feel palpitations when they have caffeine but there is no evidence to suggest greater risk of major heart problems because of coffee consumption.
Q: Will anxiety cause palpitations?
A: Yes, anxiety can cause palpitations. It's not uncommon to feel an extra beat or two, but not significant arrhythmias.
Q: Will the inferior vena cava shrink with age?
A: The VC usually gets bigger with age, so no, it does not shrink.
Q: If I were to quit smoking now after smoking for 35 years, how long will it take for me to see the benefit? I have PAD, CAD, HB AND HIGH CHOLESTEROL.
A: We see the most benefit to patients with COPD. In all other cases, stopping smoking will slow down the progression of the disease. The overall health benefits are immediate.
Q: What percentage of blockage in an artery is need to worry?
A: The percentage depends on where the artery is located. If it is a coronary artery, 50% is concerning and 75% is severe.
Q: Is the da Vinci system more reliable than manual operations?
A: Da Vinci is not more reliable. Manual or robotic - it still all depends on a human. A person still has to operate the da Vinci.
Q: Is pain in the right side of the neck possibly heart related?
A: Pain in the neck can be heart related, but generally if it is, the pain is dull and pressure-like.
Q: Where can I get information about heart healthy foods?
A: Here are some heart-healthy foods:
• Oily fish. Mackerel, sardines, tuna and salmon contain omega-3 fatty acids, which make the blood less likely to clot and block blood flow.
• Tea. Some evidence suggests that the antioxidants in tea can help cut the build-up of fatty deposits in the arteries and fight blood clots.
• SOME Alcohol. Some kinds of alcohol (such as red wine) may help clear cholesterol from the body
• Foods containing vitamin E. Avocados and dark green vegetables are among those that can clear the body of bad harmful cholesterol.
• Garlic. It will lower blood cholesterol.
Q: Will taking daily Niacin pills and fish oil help raise HDL levels?
A: Absolutely. See this link. http://my.clevelandclinic.org/heart/prevention/nutrition/omega3.aspx
Q: How low should your cholesterol be?
A: It depends on the patient and what the target cholesterol is... Overall it should be less than 200, but more important is the breakdown. HDL should be over 40. LDL target depends on your risk level.
Q: What besides 80mg lipitor, lovaza and tricor can I do to help with my hyperlipidema? I am now counting carbs. I'm not diabetic or overweight. Does the new blood cleaning treatment work?
A: Without knowing your lipid profile it is hard to give you specifics, but there are a number of ways to help. Lifestyle changes - exercise, diet, quit smoking if you do. Medications (like the ones you mentioned) and others, but you should speak directly to your doctor about those options. And also supplements like fish oil and omega 3 fatty acids. I am not sure what blood cleaning method you are referring to, but I would guess it is experimental at best.
Q: Where can I find additional research on cardiac ablations for NSVT? I am a competitive athlete, my heart is not enlarged, but I do have a low/normal ejection fraction. I am looking at what is out there for athletes and NSVT and ablations.
A: Search online for peer-reviewed journal articles and other academic/expert content, but if you are concerned you should definitely talk to your doctor or consult a cardiologist.
Q: I have fluttering in my chest and into my neck at times. Saw doctor two days ago and he doesn't seem concerned, should I be?
A: You absolutely should get a second opinion and consult a cardiologist about your flutters and neck pain.
Q: I am 50, my brother is 51. He just had 5 bypass surgery. Both my parents had bypass surgery and strokes. My mom's sister died of stroke. My gp doc says so far so good. Should I be seeing a cardiologist for preventative care?
A: Not if you have a good primary care doctor that is doing the ongoing screenings for you.
Q: What is the future of the Continuous Flow Total Artificial Heart if the FDA allows for further operations of this type?
A: There is no FDA-approved continuous flow artificial heart.
Q: Just a quick question. I am 54 years old, 160 lbs, 5'7" and have been actively working out 3-4 days a week for years. I have had palpitations most of my life off and on maybe 4-5 times a year. In the last 6-8 months when I am running and my heart rate gets to 140 the palpitations start every 3-4 minutes. I do not have chest pain or shortness of breath. I am reluctant to see a doctor because of the rate hike to insurance by having this on my record but should this be checked out?
A: Yes! Always get cardiac problems checked out and evaluated by a cardiologist. Anything that is not normal for you is cause for concern.
Q: How can I get into a study for myocardial stem cell program?
A: Keep searching http://clinicaltrials.gov/. That's the location of all clinical trials on all topics.
Q: What is more important -- total cholesterol or the ratio?
A: Calculating your cholesterol ratio can provide useful information about your heart disease risk, but it isn't useful for deciding what treatment you should have to reduce your heart disease risk. Your total cholesterol and low-density lipoprotein (LDL, or "bad") cholesterol levels are more useful in guiding treatment decisions than is your cholesterol ratio. You can read more here. http://www.mayoclinic.com/health/cholesterol-ratio/AN01761
Q: What is the name of the blood test that can help detect the level of plaque or the high potential for heart attack if you have a family history of heart disease?
A: There are several blood tests. The one you seem to be talking about is the C-reactive protein test. But you should also read about these tests. http://www.mayoclinic.com/health/heart-disease/HB00016
Q: What is microvascular heart? Will I die from this problem?
A: Here's something from the NIH: "Coronary microvascular disease (MVD) is heart disease that affects the heart's smallest coronary arteries. Coronary MVD occurs in the heart's tiny arteries if the walls of the arteries are damaged or diseased."
Q: I had a heart attack at the age of 37. In 1999 they put a stent in. In 2006 the stent collapsed and they put another one in. I have had chest pains ever since the first one. The pain is getting worse with shortness of breath, dizziness and light headedness. I have had all the tests done including stress test with dye, echo. I am on metoprolol, isosorbide, metforman, aspirin, nexium, pravastatin, effexor. Everything comes back very good. I'm scared one of these days it is going to be serious and I will just ignore it. Please any suggestions?
A: You need to talk to your cardiologist to decide if there is anything else causing your chest pain. There are more meds you could be taking if the cause is definitely cardiac-related.
Q: When we use the Continuous Flow Total Artificial Heart, what are the advantages of CFTAH over other hearts?
A: The benefits are the size and durability of the device.
Q: I was diagnosed with Cardiomyopathy. The cardiologist stated that not enough oxygen is getting to my heart. I'd like to know to assist me with getting better care what questions should I ask him; if I should request a certain test on a regular basis. I've had a cardiac cath in 09.
A: You need regular evaluations with echocardiography, blood tests for all your risk factors (cholesterol, blood sugar, etc.). Some questions to ask your cardiologist: Is your cardiomyopathy reversible? What is the cause of it? What is the long-term prognosis? What treatments and medications are appropriate?
Q: The aortic valve is being replaced without surgery. When will they start doing the tricuspid valve replacement without surgery?
A: The tricuspid is more difficult to treat. There is a higher risk of clotting. There is ongoing investigation and research in this area, but it is a less common problem than the aortic valve.
Q: What signs of heart disease should a 30 year old active woman with low blood pressure look for? What can I do to lower my risk?
A: Coronary artery disease is something everyone should worry about. You should talk to your doctor and make sure your risk factors are regularly checked - your cholesterol level, blood sugar, etc. While your blood pressure may be low now, it is important to monitor it regularly. It tends to go up with age.
Q: Is it true constant shoulder pains can be an early sign of heart disease?
A: Most of the time the pain will be between your shoulder blades. Also, read these details from Mayo Clinic: http://www.mayoclinic.com/health/shoulder-pain/MY00189
Q: Can mild heart failure be halted or is it always progressive?
A: It depends on the cause, but yes in some cases it can be halted with proper treatment.
Q: Should one also let a heart pain go? I have had a few lately but not really any chest or arm pain. Like a needle in the heart. Then it goes away.
A: There are all kinds of chest pain with a diverse range of causes. You should definitely have it checked out.
Q: What about 50% blockage in the carotid arteries in the neck?
A: That is an increased risk for stroke. Standard practice is treatment for blockages 70% or greater, but all patients with blockage are at risk for atherosclerosis. You should follow treatments to reduce your risk (aspirin) and make sure you are getting regular risk factor screenings.
Q: Will foods that lower bad cholesterol also lower the good cholesterol? Like garlic and fish oil?
A: No.
Q: What heart disease screening is available for women without insurance, especially those with a family history?
A: It depends on what type of screening you are looking for. You can have your risk factors evaluated really inexpensively (blood tests), and even in some cases for free. Consult your local hospital for reduced price screening programs.
Q: I have had my aortic valve replaced about 5 yrs. ago with a pig valve because I was born with a birth defect, bicuspid aortic stenosis. Will I be able to have the non-invasive procedure done to replace it in about 8 years?
A: The non-invasive procedure is still experimental and it is hard to predict what technology will be available in 8 years. They are doing things with catheters in Europe, but it is still experimental in the United States.
Q: Can diet medications such as adipex weaken your heart?
A: Adipex can increase your risk for pulmonary hypertension when combined with certain other medications and it is ONLY safe if you are taking it under the supervision of a doctor.
Q: I am a relatively healthy, 62 year old woman. I have a history of heart disease in my parents and grandparents. I am 40 pounds overweight. I go to the gym 5 times a week and try to eat well. I have had any number of the symptoms of a heart attack. Once about 3 years ago, I was convinced to go to the ER. It was nothing, cost me 2 days off work and thousands of dollars. Now I am out of work and have a high deductible insurance. I can't go to the doc or the hospital every time I am short of breath or feel tightness in my chest. Any suggestions?
A: You need an outpatient evaluation. Tests that are inexpensive but can determine whether the causes of your shortness of breath are cardiac-related.
Q: If someone continues to fail stress tests but nothing is found with a cath test what would be the next step? Would a heart murmur cause an abnormal stress test?
A: Not usually. You should be treated with meds and close follow-up.
Q: I heard a conference over the weekend that said arrhythmias are hereditary.
A: Read this article: http://www.netwellness.org/healthtopics/heart/heart_rhythm.cfm
"With certain genetic conditions that are inherited in a dominant fashion, a 50-50, flip-of-a-coin chance exists that each child of an affected individual will inherit the disease-causing gene change."
Q: My husband gets sharp pain on his chest once or twice a week for the last 4 years. The doctors did different tests to check if it is related to his heart, but the test result was negative for heart disease. What other disease would cause severe chest pain on the right side?
A: There are a number of possibilities. Can be related to lungs, esophagus, gallbladder or any other organ in the chest cavity. Need to continue conversations with your doctor.
Q: It seems that DRs are prescribing high cholesterol medicine to everyone. Is it really necessary? What are the risks of not taking this medicine?
A: Cholesterol medications work very well for patients at increased risk for heart attack. Medications reduce risk and prevent mortality. The number of patients at risk is always increasing which is why more people are on these medications.
Q: Do you know of any new treatments for very low HDL (24)?
A: Yes. There are many experimental new treatments and clinical trials going on for new medications. Talk to your doctor about available protocols.
Q: I have a heart murmur and a leaky heart valve. I need to have surgery to have a fistula. My cardiologist wants to do another nuclear stress test to see how the heart has progressed. Last stress test was in May. Is the stress test the best test to find out if I have any further damage to my heart or would an echo or another test give the same answers or results?
A: Not necessarily. A stress test, no matter how it's done, serves the same function. The other tests are only necessary if they find blockages. Your first line of diagnostics should be the stress test.
Q: How serious is sick sinus syndrome? I've had numerous monitors, stress tests, echocardiogram, carotid artery sonogram. All show nothing except low pulse (50-52) and premature beat. I get no answers.
A: Sick sinus syndrome is often treated with a pacemaker, but only when there are symptoms (fainting and dizziness). It is important that you continue the monitoring and tests.
Q: I have had 4 cardiac caths 4 to 5 months apart, with 5 stents placed. I still have symptoms chest pain/shoulder pain/very tired/ my doctor doesn't seem to take this serious. Is there something I need to be doing or watching for? I'm a 50 yr old female.
A: Your symptoms may not be heart-related. You should bring them up with your primary care doctor as well as the cardiologist.
Q: Can high triglycerides be caused by oral HRT being metabolized by the liver and if so, would switching to a patch avoid the elevation in triglycerides?
A: No. There are different hormonal effects on your lipids but the formulation of the hormones doesn't change the effect.
Q: I had two seemingly-healthy friends die at 54 from undetected heart disease. I turn 54 in a few months, and I have high cholesterol. I cannot take the meds to lower cholesterol. Should I get an MRI on my heart / arteries and veins to see if I have heart disease?
A: You should focus on controlling all of your risk factors and continue to have screenings to continually assess your risk. You should have an exercise test, and after consulting a doctor, obtain a coronary artery calcium score.
Q: Do elevated enzyme levels mean you have "had" a heart attack?
A: A heart attack diagnosis is made with 2 of 3 criteria. 1. Typical symptoms (chest pain, etc.) 2. EKG findings 3. Blood test findings. So with just the blood work doesn't confirm a diagnosis.
Q: Had an episode of Afib last year and afraid for it to happen again. What are the best ways to prevent skipped or extra beats or Afib if I have hypertropic cardiomyopathy?
A: There are definitely things that stimulate Afib. You should avoid alcohol and other stimulants. You should ensure you are getting proper treatment for your cardiomyopathy and confer with your cardiologist.
Q: I am taking norvasc for blood pressure. My heart rate is running in the 40's. Is this normal?
A: Heart rate and blood pressure can be related. Norvasc typically does not slow down your heart rate, but you should consult your doctor.
Q: What is the life expectancy of a pig valve?
A: 10 - 15 years
Q: I have tachycardia. My cardiologist sees me yearly. I've had an echo and numerous holters and he says my heart is healthy but just beats fast. He says it's nothing to worry about, but I can't help but worry it will damage my heart over time. I take metoprolol 100 mg 2/day and it still gets up to 104-106 with light activity and anxiety. Is there anything else I should be doing? Can this damage my heart over time?
A: It is not known if asymptomatic tachycardia is harmful long-term. Most of the time it's not harmful, but if it's very rapid (much higher than what you indicated) for a long period of time, you can develop cardiomyopathy. You should check with your cardiologist.
Q: I'm 32 with LDL of 82 and HDL of 84 - are those good numbers? or bad? Heart disease runs in my family, but I'm fairly active and take fish oil every day, but I do eat too many processed foods.
A: That is a good profile. Your HDL is excellent and is protective of heart disease.
Q: My current HDL level is at about 25. Should I be overly concerned? I am trying everything I can do naturally to raise it.
A: Your HDL level is only one of the many risk factors for heart disease. You shouldn't be overly concerned; However diet, exercise and certain medications can increase your HDL level. You should talk to your doctor. There are experimental treatments also available.
Q: My dad has been told he's high risk for receiving a stent and that bypass is not an option. His heart is extremely weak. What can be done to strengthen his heart so a stent can be done?
A: Patients who are not considered surgical candidates are definitely not candidates for a reason. It is hard to get specific without knowing the other risks involved. That said, he can always make lifestyle changes to reduce his risk and improve his heart health. He should also discuss medication adjustments with his doctor. Again, hard to get specific without more history.
Q: I have a pericardial effusion which has been present for over a year now and is located behind my heart in a very risky position. And irregular heartbeat, and slow. I have had about 8 ECG's that all state abnormal. What could be the underlying cause of this pericardial effusion and should my doctor be concerned as to whether or not to drain the fluid off my heart? I also have alpha one antitrypsin deficiency disease. Phenotype MZ diagnosed in 2000.
A: Causes can be a wide range of things - infection, kidney failure, autoimmune disease. There is no hard indication for draining the fluid. You need to continue searching for a diagnosis via blood tests and sometimes we'll consider a diagnostic aspiration of the fluid; However the yield of the aspiration is low and often doesn't outweigh the risks. Keep working with your doctors.


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Wednesday, September 3, 2014
Blu, Atalaya and Trawler, three sea turtles rehabilitated by the South Carolina Aquarium Sea Turtle Rescue Program, are ready once again for the open ocean. The release is scheduled to take place this Friday, Sept. 5, at 11 a.m. at the Folly Beach County Park and is being held in partnership with the South Carolina Department of Natural Resources (SCDNR) and the Charleston County Parks and Recreation Commission (CCPRC). Attendees should plan to carpool, arrive early (gate opens at 10 a.m.), and expect to pay for parking at the county park. After the release, BLU Restaurant and Bar, located at the Tides Hotel on Folly Beach, will donate 10 percent of the proceeds from its Sept. 5 lunch service to the Sea Turtle Rescue Program. For the first time ever, the aquarium will be using Instagram's new Hyperlapse app which captures high-quality time-lapse video. That video will be posted to the aquarium's social media channels directly after the release.
Blu, a juvenile Kemp's ridley (the most endangered of the sea turtle species) was accidentally caught on a hook and line by a fisherman on the Edwin S. Taylor Folly Beach Fishing Pier this past July. Blu swallowed the hook and was transported to the aquarium's Sea Turtle Rescue Program by SCDNR. The aquarium's consulting veterinarian, Dr. Biaschoechea, surgically removed the hook from Blu's esophagus. A few days after surgery, Blu's appetite returned and after just two months of care, Blu has been medically cleared for release. Blu is named after BLU Restaurant and Bar located at the fishing pier where s/he was caught.
Atalaya, an 80-pound loggerhead sea turtle, was admitted to the aquarium's Sea Turtle Rescue Program the same night as the aquarium's annual Environmental Stewardship Awards Gala. Atalaya was found stranded on the beach at Huntington Beach State Park in Georgetown County in early May and was deathly ill. Atalaya was emaciated, dehydrated, severely anemic and had intestinal parasites. Treatment included fluids, antibiotics, vitamins and a healthy diet. Atalaya was in critical care for a full month before aquarium staff started to see substantial improvements in her health. Atalaya is now feisty and back to a healthy weight, swimming around his/her holding pool in preparation for the trip back into the open ocean.
Trawler, a 123-pound juvenile loggerhead sea turtle, was captured by the SCDNR research vessel, Lady Lisa, in late June. Trawler had an unfortunate encounter with a stingray that was caught in the same net and was punctured by the stingray's barb. Upon admission to the Sea Turtle Rescue Program, Trawler was given fluids, antibiotics, pain medication and the wound was treated and monitored. With the wound fully healed, Trawler is ready to join the loggerhead population in the Atlantic Ocean.
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California Classic Dinner Cruise
The "California Classic" Dinner Cruise is a popular tradition of our most prestigious corporate charter groups. There's plenty of time to mix and mingle aboard the yacht as you cruise past treasured San Diego landmarks, and then make your way to tables for dinner and views that change with the courses.
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Just disembarked from the Lord Hornblower in San Diego. Your crew did a fantastic job for several hundred California travel industry leaders. Great food, outstanding service, smooth sailing by naval pros. Thanks for supporting the conference and treating everyone to the experience that you provide visitors everyday.
– Bradley M. Burlingame, CEO, Visit West Hollywood
I wanted to say thank you to you and your staff for the outstanding event you and your staff put on for our customers aboard the Inspiration Hornblower. We have heard nothing but positive comments from our guests, staff and executive management and it is because of you and your staff that this event was such a success! The service, professional manner everyone handled themselves and attention to detail compares to nothing I've seen in the industry. It was truly a pleasure to work with all of you. I had the opportunity to board the ship during set up to travel to the dock with the staff and found each one of them to be a joy to work with. They were all so excited to get the party started and when it was time for our guests to arrive they turned on the professionalism one would expect from their staff when representing their company. You should be extremely proud of them. The ease of working with you is wonderful. I know I am in safe hands when you are working on our account and the addition of Corena is wonderful too! She was such a help the day of the event when we were going over the final dinner count. I would also like to thank you for the help in finding our furniture and entertainment for the evening. Both companies were used at our last event and were outstanding and they were just as good this time. The staff and guest are still raving about the Heroes! I cannot say thank you enough nor find the words to express just how great of a job everyone did making this a success. I appreciate all of your help and am looking forward to working with you again when we come back.
– Tracey Czechan, Cooper Power Systems


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As Immunotherapy Revolutionizes the Cancer Treatment...
Wall Street Decline Takes Its Toll...
Expanding Use of NGS Has Largely...
LC-MS Gains Favor Due To the...
Oxytocin is no simple molecule. It consists of 135 atoms (nine amino acids) totaling 1 kilodalton (kDa). It pushes up against the size limits of common techniques like GC-MS, but it remains squarely in the realm of synthetic drugs because it is commonly made via a synthetic chemistry pathway.
There's little room for variation; the polypeptide is unadorned and it's a fairly simple task to verify you have pure oxytocin in your tube, and that it's the exact same molecule, in form and function, as the one used to pass clinical trials.
Get a little bigger, however, and we start to enter biologic territory. Insulin is a popular one, at 5.8 kDa and 51 amino acids. It's small (for a protein) and has come from both animal and E. coli sources for decades. There's even a set of biosimilar insulin guidelines from the EMA, so approval should be easy.
As of now, all of the insulins available on the EU market were approved using the standard pathway for new drugs. Only one company attempted to enter the EU insulin market through the biosimilar route, and it failed. Marvel Lifesciences applied in 2007, claiming their insulin formulations were similar to Lilly's Humulin.
There were numerous problems with the application: Critical information was missing, ranging from tracking numbers on product lots to chemical analysis on lots used in the PK, PD, and safety trials. The trials themselves were too short, and poorer performance versus reference in PK and safety trials did not help their case.
Another company, Biocon, recently ended its year-old collaboration with Pfizer to bring biosimilar insulin to markets; Biocon will be left to fend for itself in this regard. I don't anticipate them having too much trouble getting approval, but they may have to wait: New guidelines for insulin analogues haven't been released yet (the commentary ended last year).
Even so, one wonders, why are trials necessary? Wouldn't proof of identical composition be sufficient? Such proof is not forthcoming. Biologics are too large to examine every atom and their source processes too variable to be assured that a biosimilar is indeed identical. A small amount of protein background might be permissible with one host organism, but immunogenic with another. Host organisms can decorate their protein products differently, leaving different sugar chains or amino acid modifications. In some cases, different glycosylation patterns can be advantageous, producing a longer-lasting product, but these changes also mean that previous data on pharmacokinetics no longer applies and dosing regimens would have to be adjusted.
Finally, considerations such as protein aggregation and misfolding mean that changes in product packaging can have more severe results than they would with small molecule drugs. In 1998, the epoetin-alpha product Eprex was switched from human serum albumin buffer to polysorbate-80 and glycine. It is suspected that the subsequent increase in protein aggregation in transit/storage led to greater immunogenicity and caused a sudden rise in cases of antibody-mediated pure red cell aplasia, a serious and potentially lethal autoimmune disease. Post-market surveillance caught this, and the contraindication of subcutaneous administration (generally more immunogenic) prevented more cases.
The idea of drug packaging influencing the drug's behavior is nothing new; it's how "extended release" forms of small molecules are developed. However, when combined with the subtle and numerous ways in which manufacturing processes influence the biologics they produce, it makes sense that the EMA would pursue a "one process = one product" approach. With both general guidelines and specific guidelines appropriate for particular classes of biologics, the EMA is properly handling the question of how to evaluate biosimilars.
But other questions remain: As assay technologies and expression systems continue to improve, will we ever see two different manufacturers with different processes make identical biologics? Can the biosimilar approval model be used for approving biologics with intentionally different kinetics? What level of similarity is worth pursuing? In the event that a biologic finds a new indication, how will the approval of that indication for approved biosimilars be handled?
It's not necessary to know everything about a drug to declare it functionally identical; there's little interest in the isotope profile of aspirin or the average molecular weight in polymer gelatin capsules. However, without a complete understanding of how form relates to function and the analytical tools to prove it, we won't be able to set out a minimal list of analytical tests to show that two biologic products are functionally identical and not just similar.
The EMA's approach of making class-specific biosimilar guidelines is well-suited to match the evolving understanding of these products. We're about to see the first biosimilar mAb go up for approval, and there are already approved somatotropins and epoetins.
However, guidelines aren't everything: the EMA guideline on recombinant insulin was one of the first ... so where's the biosimilar insulin? Lilly applied for FDA approval of its recombinant insulin 30 years ago this week, and three months later it was approved. In some ways, it was the first biosimilar, mimicking a biologic but made through a radically different process.
We've waited 30 years—perhaps now, with the insulin analogue patents soon to expire, we can see the first pharmaceutical product of genetic engineering come full circle.
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Novum Pharma recently raised the price of an acne cream by over 3,900% in less than a year-and-a-half and Mylan increased price of EpiPen from $100 to $608 . Do you think pharmaceutical companies need to be subjected to price controls?
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The authentic natural and cultural landscape of the Puschlav which is 25 kilometres long as the crow flies extends from the giant ice peaks of the Bernina Mountain Range all the way down to the vineyards of the Veltlin. Woven into it are a great many sites of natural beauty, pretty towns with interesting cultural monuments, churches and palaces.
The train journey over the Bernina Pass (in winter the road over the pass is sometimes closed) from St. Moritz to the Puschlav and to the Italian border in Tirano is an impressive experience. Time and time again vistas of the mountainscape of the Morteratsch Glacier, Diavolezza or Lagalb open up. From Alp Grüm you enjoy a view of the imposing Palü Glacier and at the same time you can see the Lago di Poschiavo deep down at the bottom of the valley. The railway line into the Puschlav with a gradient of 70 per mill is the highest rail link across the Alps and among the steepest narrow gauge railway lines without a rack in the world - a railway engineering feat.
The centre of the authentic Puschlav holiday universe is the small town of Poschiavo whose imposing patrician houses frame a Piazza with an Italian air. One of the many architectural special features is the "Spaniolenviertel" with its colourful houses and was built by emigrants. The guesthouses in the Puschlav valley, which is characterised by agriculture, serve a great many regional specialities.
The unspoilt countryside of the Puschlav and its side valleys, such as the Val di Campo nature preserve with its mountain lakes, for example the cobalt blue Lago di Saoseo, is best explored on foot. In Cavaglia impressive glacier mills - nicknamed "Giants' Cauldrons" - bear witness to the last ice age and are an interesting sight. The Lago di Poschiavo (or Lake Puschlav) is perfect for a spot of water sports in summer.
In winter visitors are attracted by the nearby Engadine ski regions of Diavolezza and Lagalb. The Val di Campo boasts a snow fun park.
- Town of Poschiavo – Italian charm in the Grisons.
- Alp Grüm – stunning vantage point at an altitude of 2091 metres above sea level by the Bernina Pass with a view of Piz Palü (3889 metres above sea level) and the Lago di Poschiavo.
- Bernina Railway – part of the Rhaetian Railway from St. Moritz to Tirano, with a gradient of 70 per mill is one of the steepest railways without a rack.
- Circular viaduct of Brusio – the Bernina Railway describes a 360-degree curve across the viaduct which is a popular photo subject.


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Nicki Minaj from her 9/27/13 guest appearance on "The Ellen DeGeneres Show."
Ellen was so inspired by Nicki's outfit...
...She dressed up as Nicki Minaj for her Halloween show!
Ellen made sure she included every "detail" in her costume.
Also joining Ellen in the Halloween fun is "So You Think You Can Dance" star, tWitch, as her DJ dressed as John Travolta in "Saturday Night Fever".
Ellen later welcomes actress Alison Sweeney who comes dressed as Christina Aguilera sitting in her chair on "The Voice."
Be sure to tune in to "Ellen" today to see more of the Halloween fun!
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4. Building Drupal Web Farms with IIS – part 2
- Posted: May 21, 2012 at 2:22PM
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This is the second of two wecasts dedicated to how to create a great Drupal web farm on IIS. Get ready: in less than one hour we'll create a drupal web farm from scratch, by using four virtual machines: a load balancer running ARR and WFF, two hosts provisioned automatically via Web Deployment Tool running the Drupal web site and a host running MySQL and providing file shares.
You can also reproduce all the demos on any PC or laptop equipped with at least 8GB of RAM. Here are all the instructions used during the demo. Just download your free copy of Windows Server trial edition and run it on your favorite virtualization software, on Windows, Mac or Linux.
If you have any questions please contact @alexpilotti or @gracefr.
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Durango resident Cole Fischer Behr died from injuries suffered in a car accident Wednesday, Oct. 3, 2012, on East Animas Road (County Road 250) north of Durango. He was 22.
Mr. Behr was born to Fred and Cindy Behr on June 2, 1990, in San Jose, Calif. His family moved to Durango in 2001. His family has deep roots in the area on his mother�s side, with one ancestor who was born in Rockwood in 1887.
Mr. Behr graduated from Durango High School in 2009.
He enjoyed horseback riding, working out and eating pizza. He also liked Nia dancing, a sensory-based movement practice, listening to music of all types, including country western and rock, and watching football, especially the Denver Broncos. Among his favorite memories were the two Broncos games he was able to attend in person, his family said.
�Cole woke up happy every morning and brought a smile to all he met,� his family said.
Mr. Behr is survived by his father, Fred Behr, of Durango; mother, Cynthia Weber, of Hesperus; sister, Katie Behr, of Seoul, South Korea; and grandmother Myrna Ford of Durango.
A memorial service will be held at 11 a.m. Monday, Oct. 15, 2012, at St. Columba Catholic Church, 1830 East Second Ave. A reception will take place afterward at Iron Horse Pizza, 400 S. Camino del Rio.


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Jared Thomson
Westminster College Student Spotlight: Jared Thomson
Major: Theater
Hobbies/likes: reading scripts, gardening
Hometown: Bountiful, Utah
Why did you choose Westminster over other schools?
I chose Westminster over other schools primarily on their reputation as an excellent educational institution. Here, professors become lifelong friends and mentors.
What do you particularly like about your major?
The new Theater major has the potential to help me reach my personal and professional acting goals.
What do you plan to do after graduation?
After graduation from Westminster, with a BFA and hopefully a Masters of Education, I plan to inspire and educate young adults in the theater craft!
How do you feel about your learning experiences at Westminster?
Thus far, my education at Westminster has led me to new insights about myself and my potential to utilize the knowledge attained here to further greatness.


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Healthy Baby, Healthy Start
Just over 4 million babies are born in the United States every year. Their mothers and fathers make up a wide range of socioeconomic and age-related demographics. In 1970 the average age of a first-time mother was about 21. In 2008 the average age was 25.1.
Efforts to improve birth outcomes in the United States are ongoing.
According to the Centers for Disease Control: about 25,000 infants die each year in the United States. Pregnancy and childbirth have a huge impact on the physical, mental, emotional, and socioeconomic health of women and their families. Pregnancy-related health outcomes are influenced by a woman's health and other factors like race, ethnicity, age, and income.
WQED is pleased to collaborate with Highmark in addressing the important topics of better maternal and infant health during pregnancy and baby's first year life. This four part series: Healthy Baby, Healthy Start will explore issues related to maternal nutrition, infant mortality, safe sleep for babies and high risk pregnancies.
WQED-TV Special Reports
Infant Mortality - WATCH NOW
In Pittsburgh, where the unemployment rate is well below the national average, the infant mortality rate for black residents of Allegheny County was 20.7 in 2009, a slight decrease from 21 in 2000, but still worse than rates in China or Mexico. Because racial and ethnic minority groups are expected to comprise an increasingly larger proportion of the U.S. population in coming years, the number of people affected by disparities in health care will only increase without culturally appropriate, community-driven programs to eliminate these disparities. To be successful, these programs need to be based on sound prevention research and supported by new and innovative partnerships among governments, businesses, faith-based organizations, and communities. This story will explore organizations working within minority communities to encourage better prenatal and newborn care.
Discussion to follow: Host Chris Moore talks with local experts about infant mortality problems -- and most importantly -- prevention. Guests include: West Penn Hospital neonatologist Dr. Bindu Raveendran, Clinical Director of the Midwife Center for Birth & Women's Health Ann McCarthy, and Healthy Start board member Peggy O'Malley.
Resources, Links & More Information:
The Midwife Center for Birth & Women's Health
Healthy Start Pittsburgh
West Penn Hospital Neonatal Intensive Care Unit
Allegheny County Health Department Maternal and Child Health Program
The Birth Circle (Doula program)
Center for Health Equity
University of Pittsburgh Graduate School of Public Health
Behavioral and Community Health Sciences
Maternal and Child Health Program
Allegheny County Health Department
What Should Mother-to-be Eat? - WATCH NOW
Good prenatal nutrition is essential for the growth and health of the developing fetus. So what's on the checklist of good food, and what should moms-to-be avoid? Research also indicates that poor maternal nutrition could even lead to childhood obesity. We'll talk to experts who have great advice and hear from the mothers who are taking that advice.
Safe Sleep - WATCH NOW
This report explores the tragedy of infants who die unexpectedly while sleeping. Parents can reduce the risk of sudden infant death syndrome or SIDS, by following a few simple safe sleep guidelines offered by experts in the field. Also profiled: "Cribs for Kids." This national Infant Safe Sleep Initiative headquartered in Pittsburgh is a voluntary health agency whose mission is to provide education and support to families, friends and communities affected by SIDS.
Resources, Links & More Information:
Cribs for Kids
When can I give my child a pillow?
Healthy Start Pittsburgh
SIDS Safe Sleep Tips for Infants
High Risk Pregnancy - WATCH NOW
When a high profile woman has a high risk pregnancy the whole world pays attention. In Great Britain, Kate Middleton made headlines while suffering from hyperemesis gravidarum, or severe morning sickness - which is among the factors that can lead to high risk pregnancy. But royal family aside, millions of other women experience high risk pregnancies. This report will highlight some of the other factors, including advanced maternal age, lifestyle choices such as smoking and drinking, diabetes, high blood pressure and epilepsy. We'll talk with pregnant women who've been affected and report on what women should know about care and prevention.
Resources, Links & More Information:
March of Dimes
March of Dimes CineMama
West Penn Allegheny Health System - High-Risk Obstetrics and Maternal-Fetal Medicine
Centers For Disease Control - Reproductive Health
Check out our new blog from producer Alicia Schisler!
Half Hour Special on Postpartum Depression: Beyond Baby Blues


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Jealous neighbors and dogs will be watching in envy as you and your pooch can enjoy walks in the rain while keeping dry. Featuring bows, hearts, and roses, in varying shades of pink, this is the ultimate girly-girl raincoat. Not only is it stylish, but it is easy to clean and has a D-ring attachment for a leash. Lined with cotton and including Velcro closures, this coat is comfortable too!
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Maui County is seeking bids for a company to convert the island's solid waste into energy in an effort to cut down on the amount of trash that ends up in the Central Maui Landfill in Puunene.
The Department of Environmental Management is taking proposals until Jan. 16 of any established technologies that can turn municipal waste into a green resource.
"We're not asking for a specific type of technology. We're asking for a proven record of a minimum of three years at the commercial level, and a facility that has the capacity to handle what Maui generates, which is about 450 tons a day of municipal solid waste," said Michael Miyamoto, deputy director of the Department of Environmental Management.
Article Photos
Garbage trucks dump their loads at the Central Maui Sanitary Landfill last month.
The Maui News / MATTHEW THAYER photo
The department would lease approximately 10 acres of land next to the landfill to the winning bidder, who would be required to finance, design, build and operate the project. The county would make available all of its waste streams - including solid waste, green waste, sewage sludge and grease - and guarantee sending the waste to the facility for 20 years.
"This is an opportunity to convert what we take in at the Central Maui Landfill into some other form, whether it's converted to energy that can be sold to the electric utility, or some kind of biofuel or other fuel source," Miyamoto said.
The formal request for proposals - which was issued last week - follows a so-called request for qualifications in March that attracted some 70 interested parties.
Miyamoto said that the initial submittals included "a good mix of technologies," including gasification processes and producing methane as an energy source.
The department has said that an incineration facility - like the City and County of Honolulu's HPOWER facility that can burn up to 3,000 tons of waste a day - is an unlikely candidate for Maui's needs.
"Being that we're on the order of 450, 500 tons per day, I don't think that incineration will be the option that comes out the best just based on - it's too low of a scale," Department of Environmental Management Director Kyle Ginoza told the Maui County Council's Infrastructure Management Committee last month.
Ginoza said only about 30 percent of the county's trash is "diverted" from landfills and either recycled or put to some other use.
"One way to significantly increase diversion is through implementation of a waste conversion project, a project where less than 10 percent of inert waste from municipal solid waste ends up being landfilled," he told the committee. "It is not uncommon that there is 80 to 90 percent landfill diversion through a waste conversion project."
While one draw would be the potential to sell any renewable power generated to Maui Electric Co., that potential is uncertain at this point, he said.
Maui Electric has been wanting to issue its own RFP for a waste-to-energy plant near the landfill. Whatever project ends up winning the county's bid could potentially apply for MECO's bid, but MECO has yet to issue its RFP.
"We don't want to be, you know, five years from now and we're just waiting on our project because (MECO is) still trying to figure out theirs," Ginoza said.
He said MECO's willingness to buy power would determine what end product the county seeks in deciding on a technology.
"It's kind of a chicken or the egg where we stand as a county, in that we cannot negotiate what a final purchase agreement would be because we don't know what our project is, and yet how do you get a project without knowing somebody will take that energy," he told the council. "The biggest complication for me is I don't want to mislead people to think that, oh yeah, there's a market for, you know, there is a definitive revenue stream for you on the back end, when there may not be."
He said the department continues to have conversations with the utility.
Outgoing Council Chairman Danny Mateo told Ginoza that he was encouraged by the potential project and that he believes the county "no longer can just wait anymore."
"I think we've gotten to the point where we've got to start pushing ourselves and taking a look at new challenges, new resources, and new opportunities," Mateo said. "We're real cognizant of cost factors, especially in new creations of landfills, and then the most obvious one, the closure of landfills. You know, it's really astronomical for us. So the longer we can expand the life of a landfill by looking at these options, I think we're better off."
Council Member Mike Victorino added that generating renewable power would be an added bonus to the underlying need for reducing landfill space.
"We need to look at some way of disposing of solid waste and if we create energy as a byproduct, that's good. But that's not the main reason we're doing this; it's because we have a finite amount of land," he said. "And even if it's 50 years from now, 100 years from now . . . if we wait until a point where now we got to start shipping refuse off the island, that's an environmental nightmare just waiting to happen."
Ginoza agreed, noting, however, that a developer would be able to recoup its costs by selling energy or a fuel byproduct.
"Definitely we're looking at it being a paradigm shift from waste disposal to utilizing it as a resource, which the primary positive benefit is; we're not filling our land with opala," he said. "And that the energy side of it just helps make it work financially."
Miyamoto said the department expects to review bids in January and February and make a decision in time for any budget implications to be reflected in the county's upcoming fiscal year budget.
He said that the department estimates a project could come online in the next three to five years.
Copies of the RFP can be obtained through the Department of Finance's purchasing division by calling 249-2403 or by visiting the office at 2145 Wells St., Suite 104. A request form for the bid document
can also be obtained online at www.co.maui.hi.us/index.aspx?nid=509.
An informational meeting is scheduled for Nov. 27 to answer questions and to show interested parties the leasable site near the landfill. For more information, call the Environmental Management department at 270-8230.
* Nanea Kalani can be reached at email@example.com.


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Happy New Year 2015 To All Local Businesses and Shoppers
Tips For A Better Home Inside And Out
More than half of the homeowners in the United Kingdom have done their own home improvement or have had help from a local handyman services. Home improvement projects generally have one of the following as their goals: comfort, increased salability, energy savings, and basic maintenance and repair. There are many resources out there for the homeowner looking to engage in their own home improvement projects.
Your porch might be in need of a fresh coat of paint. Utilize exterior paint that is of high quality. You should match the old paint, whether oil based or water based, if at all possible. The unparalleled durability of oil-based paint makes it ideal for trim, but it's inappropriate for decks or porches themselves (precipitation makes it slippery).
If your rooms are looking rough because of nicks and dents in your wall, then you should try putting toothpaste in the hole to patch it up. Toothpaste can fill small nicks easily and can keep your room looking great. This is a cheap alternative and a quick fix.
Recycle the molding in the closets of your old house to finish out your renovation project! Sometimes, finding molding to match the molding from old houses can be almost impossible. One option is to remove the molding that is, likely inside your closets. You'll never notice that it's gone and it will be restored to its glory, out in the open where it can be seen.
When it comes to home improvement, go with your gut feeling about the contractor as long as everything else matches up. Do not even consider someone that you do not fully trust, as you probably have that feeling for a reason. If you have a hint of mistrust toward the contractor that you meet with, it may only lead to anger and mistrust on an exponential level if things do not go according to plan.
When you are deciding what it is you want to remodel ask for opinions. You want to make sure you are giving off the right vibes when you are choosing how to remodel your home. Ask for advice from neighbors or close friends and family. Sometimes other people's advice can help you in the decision making process when remodeling your home.
Update your bathroom to make your house feel like a home. Every member of the family spends quite a bit of time in this room, but we often overlook giving it an update during a remodel. You can do easy changes by replacing wallpapers, lighting fixtures, and cabinetry, to create a fresh look.
When it comes to home improvement, small things such as replacing your central air blower's air filters are essential. This is important both to the efficiency of the blower, as well as being a necessary maintenance procedure. If you allow dust and dirt to gather and even bypass the filter, it will gather within the moving parts of the blower and eventually cause it to fail.
As the article states, there are many resources out there to assist with home improvement projects. A conscientious homeowner will do much research before beginning any type of home improvement project to insure that they have the correct materials and tools on hand to complete the project and ensure a successful improvement.


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Perfect for the bath or outdoor fun!
Bathtime and outdoor play just got more fun with Bathworld. It fits perfectly in the tub or stands on its own. Kids will love pouring water into the top and watching it swim through the water wheel, pump, and other fun surprises! Made from heavy duty plastic, this toy can sustain even the toughest playtime! For ages 3 years and up.
Bathworld Includes: crane boat, pump, water mill, water wheel, and other fun water accessories
Bathworld Dimensions: 21.8" x 14" x 22
WARNING: CHOKING HAZARD-Small Parts. Keep away from children younger than 3 years.


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May 072012
I accidentally discovered this package for debian, very trivial but brilliant in its simplicity: at the first error done on the command line it performs a
rm -rf / , so it try to delete the drive completely, this package is called Suicide Linux, and you should absolutely not install it on your machine.
To test this you can use an expendable virtual machine .
Continue reading »


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has already sold 1
million Galaxy S smartphones in the United States, with just the
variants on T-Mobile
(branded the "Vibrant") and AT&T
(branded the "Captivate"). Now as a launch of
Verizon's variant, the "Fascinate", appears to be just
weeks away, Sprint has become the third major U.S. carrier to
officially open sales of the device.Sprint's Galaxy S
variant, dubbed the Sprint
Epic 4G, is a bit different than the rest of the Galaxy S pack.
It's the Galaxy S Pro which means it has a half-width, slide-out
physical keyboard, which will delight some disappointed by the lack
of a keyboard in other variants. The phone also adds in some
features that were scrapped in the "Vibrant" and
"Captivate", namely a front-facing camera for video-calling
and a rear-facing LED flash.On top of those advantages over
its Galaxy S brethren, the new phone will be compatible with Sprint's
growing fourth generation (4G) wireless network, which employs
WiMAX. Many users are already enjoying this union of that
network and another Android smartphone, the HTC
EVO 4G. However, the Epic 4G sports a faster processor than
the EVO 4G, so it should offer an even more compelling
experience.The only disappointments initially appeared to be
a slightly fatter width due to the extra features and a slightly
higher price of $249.99 USD. Apparently some e-tailers are
remedying the latter issue, offering the phone for $199.99 USD.
Both Amazon.com and Wirefly are
offering the phone at this rate with free shipping.The phone
is already on sale in Sprint stores and will start shipping
immediately. For customers who want to see more specs, you can
visit Sprint's page for
the phone, but again beware, you probably don't want to buy it there
as Sprint is charging $249.99 USD with a new 2-year-contract.
quote: My complaint is the shady way Sprint is going about this. If they told consumers the fee was for their costs to roll out a 4G network (as you claim that's what it's for - and to be fair, it certainly seems like it is) then I would accept that. If they said it was a rental fee for the phone and that you didn't really own it, I would have a different set of complaints, but ok. If they said "Simply Everything" really isn't everything and it's "Simply Everything for our older phones", I'd be ok with it. Or if they said it was to subsidize the high cost of the phone and it would stop when your contract was up, ok. Or if they actually gave you some "premium data" like exclusive apps or prioritized network traffic, I'd be ok with it. Or if they gave you free WiFi tethering, and didn't charge you $30 more a month for that. Or if they only charged it to the highest volume data users (since they claim they think you'll be using more), then ok. But to tout the phone's features (which consumers will be paying a $200 premium for, mind you) as some kind of "premium data " that can't be found on any other phone with any other carrier, is absurd. The company is trying to hide behind the premium data label without being honest about why they're charging that fee.


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Late Golden Girls stars Rue McClanahan and Bea Arthur are being honored... with ice cream!
New York's famous Big Gay Ice Cream Shop is opening up a new location in the West Village, and adding another Golden Girls-inspired item to the menu. (Arthur was already a fixture at the original.)
Which TV shows should reunite?
So what exactly are the treats made of?
The Rue McClanahan ice cream sandwich consists of bourbon-flavored ice cream between pecan praline cookies, while the Bea Arthur is vanilla ice cream with dulce de leche and crushed vanilla wafers. Yum!What other TV stars deserve their own desserts?
View original Ice Cream Shop Honors Golden Girls at TVGuide.com
Other Links From TVGuide.com
- The Golden Girls
- Bea Arthur
- Rue McClanahan
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From GPS units to cell phones to SYNC
in-car infotainment systems, U.S. drivers have found new ways to
distract themselves while driving thanks to technology (not to
mention other favorites such as applying makeup, eating, reading the
newspaper, etc.). Texting while driving is the latest craze to infect
drivers and states around the country are swiftly implementing laws
to make such activities illegal. Texting is already banned in 19
states, and 23 states are currently prepping their own laws to tackle
the problem.
"Legislators are looking to see if
it (texting) is enough of a safety issue that they need to
intervene," said Anne Teigen told
the USA Today. Teigen is a transportation specialist for
the National Conference of State Legislatures. "They often get
involved because there's a high-profile accident that had to do with
texting. Also, because everybody has a cellphone now."
While states are currently going it
alone in drafting "no texting while driving" laws, there
are a few nationwide texting bans that drivers should heed. President
Obama issued
an executive order at the close of 2009 banning all federal
workers -- rather, those on the job -- from texting while driving.
The ban affects roughly four million federal workers.
Now a new, federal ban is coming down
from the U.S. government. The latest nationwide texting ban applies
to drivers of big rigs and buses. "We want the drivers of
big rigs and buses and those who share the roads with them to be
safe," said Transportation Secretary Ray LaHood. "This is
an important safety step and we will be taking more to eliminate the
threat of distracted driving."
Drivers that choose not to abide by the
new law face a fine of $2,750.
The bans from both the states and the
U.S. government come on the heels of numerous studies which point out
the dangerous consequences of texting and driving. A study by the
University of Utah showed that drivers that text behind the wheels
are six times more likely to be involved in a collision. The National
Security Council notes that roughly 200,000 accidents are caused each
drivers who text behind the wheel.
However, it's wishful thinking to
believe that nationwide texting bans are going to stop people from
partaking in America's favorite electronic pastime. Reuters
has previously reported that teens aren't
persuaded to stop their texting addictions just because there are
laws on the books to prohibit the act.
"What I would say is that texting
and cell phone devices have become such a component of life for teens
and for young people that it's hard for them to differentiate between
doing something normal and doing something wrong," remarked
Steven Bloch, a senior research associate for the Automobile Club.
Considering that texting while driving
isn't a habit that only affect teenagers, it's more than likely that
drivers in a more "advanced state of age" are reluctant to
stop the practice as well.
While the current nationwide texting
bans affect a relatively small portion of the entire U.S. driver
pool, Senator Chuck Schumer (Democrat, NY) is looking to change that.
Senator Schumer has introduced legislation that would call for a
federal ban on texting while driving. States that don't comply with
the legislation would be see a 25 percent cut in the federal highway
funds they receive.
quote: Driving is a privilege that most Americans take for granted.
quote: Um then start a movement to amend the Constitution.
quote: What is a right? A right is a gift from God that extends from our humanity. Thinkers from St. Thomas Aquinas, to Thomas Jefferson, to the Rev. Dr. Martin Luther King, Jr., to Pope John Paul II have all argued that our rights are a natural part of our humanity. We own our bodies, thus we own the gifts that emanate from our bodies. So, our right to life, our right to develop our personalities, our right to think as we wish, to say what we think, to publish what we say, our right to worship or not worship, our right to travel, to defend ourselves, to use our own property as we see fit, our right to due process – fairness – from the government, and our right to be left alone, are all rights that stem from our humanity. These are natural rights that we are born with. The government doesn't give them to us and the government doesn't pay for them and the government can't take them away, unless a jury finds that we have violated someone else's rights.What is a good? A good is something we want or need. In a sense, it is the opposite of a right. We have our rights from birth, but we need our parents when we are children and we need ourselves as adults to purchase the goods we require for existence. So, food is a good, shelter is a good, clothing is a good, education is a good, a car is a good, legal representation is a good, working out at a gym is a good, and access to health care is a good. Does the government give us goods? Well, sometimes it takes money from some of us and gives that money to others. You can call that taxation or you can call it theft; but you cannot call it a right.A right stems from our humanity. A good is something you buy or someone else buys for you.
quote: Driving is not some hoity-toity privilege, people. For some of us, it's our only economic life support.
quote: Nowhere in the constitution does it say that the federal government can control what I eat, therefore I actually do have a constitutional right to eat a cheeseburger. Now, you may be able to argue about 'providing for public welfare' or one of the other clauses, but it would be a damn hard sell.
quote: The Federal government has a right only to regulate commerce between states. The individual states themselves are responsible for what happens within their own borders.


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Java for Mac OS X Updated for Snow Leopard, Lion, Mountain Lion
Don't know why I installed Java for Mac, but there it is. Sort of like an ex-girlfriend's cat that you're obligated to taking care of. Fresh Mac for Java versions are available from the good people at Apple for the last three versions of OS X.
• Java for OS X 2013-001, download
— Scans for common variants of the malware in question and removing them
— If malware is found, the user will be notified of its removal
— Java for OS X 2013-001 delivers improved security, reliability and compatibility by updating Java SE 6 to 1.6.0_41
• Java for Mac OS X 10.6 Update 13, download
— Java for Mac OS X 10.6 Update 13 delivers improved security, reliability and compatibility by updating Java SE 6 to 1.6.0_41
As these are Java for Mac updates, security content features prominently.
Do you have Java for Mac installed and do you actually use it? If yes, how important is Java for mac to you…
Sound off in the comments below…
Related posts:
— Mac Security: Adobe Patches Zero Day Flash Exploit
— Java for Mac OS X 10.6 Update 12, Oracle Patches Available
— Best Mac AntiVirus? You Have Choices
— Mac Antivirus: Intego Virus Barrier, Net Barrier Save 30%
— Mac Security: XProtect Update Obviates Java Exploit [u]


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Kenmore 30" Electric Combination Wall Oven
$412.23 - $1,030.75
1 year parts and labor
Find Out More »
Kenmore — trusted in the homes of more than 100 million Americans. 30 in. Kenmore electric combination oven 48852 has convenient microwave cooking in the upper oven with a lower self-cleaning oven. Microwave features sensor cooking with defrost , popcorn and delay start. The microwave features a 2.0 cu. ft. capacity, 1,100 watts of cooking power, 11 power levels, sensor cooking and a turntable.
- Cook & Hold Warm automatically keeps food warm in the oven at perfect serving temperature; you can use it as a separate feature to keep cooked foods warm or add at the end of a timed-bake function
- You can leave the durable oven racks in the oven during the self-cleaning cycle and they won't discolor
- The large 4.2 cu. ft. self-clean oven accommodates multiple dishes and features heavy-duty handle-style oven racks that pull out easily with an oven mitt /li>
- Lockout feature is activated by the push of a button to prevent accidental use of the oven controls
- The right light - the oven light comes on automatically when the oven door is opened and can be activated at any time to check on cooking progress
- The oven light comes on automatically when the oven door is opened and can be activated at any time to check on cooking progress
- Select Clean with variable self cleaning times lets you choose the amount of cleaning time to fit the amount of soil
- The wall oven fits flush to the cabinetry for a sleek, stylish built-in look
Specifications & Dimensions
Product Documentation
Owner's Manual - Spanish (Warranty)
Owner's Manual - English (Warranty)
Installation Guide
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