text:
BEST ENTRANCE: Macy's Apparel OR CVS
LOCATION IN MALL: Next to PacSun, across from Auntie Anne's Pretzels
(508) 778-5209 | Driving Directions | Bath & Body Works Website |
View Deals | Mall Map
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Sweet Cranberry Rose is the perfect autumn blend of cranberry nectar, pear leaves & rose petals.
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Lisbon Area Amateur Radio Association
WE are an amateur radio group those hold meetings on the third tuesday of the month, we are a non-profit group are goal is for the advancement of the radio art and emergency prepareness and technical expertise. We are currently acepting application for membership for those Amateur Radio operators that shows an interest in helping in times of emergency's we are here to help in times of disasters here for Skywarn which we have as spotters in the field, training are provided at times when the EMA director sets them up. also we do care to help Hams understand their radio, so try coming to the meeting third Tuesday @ 6:00
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Submit News
Bill Gates Agreed with Ballmer: Sinofsky Had to Go
Tiffany Kaiser
November 13, 2012 2:43 PM
comment(s) - last by
Nov 29
Recipient E-mail
Sender E-mail
Ballmer and Gates recognized that Microsoft needs to be more united internally across different divisions, and that change would be difficult with Sinofsky around
It turns out that Microsoft software head
Steven Sinofsky's departure
wasn't so sudden, and none other than Bill Gates was onboard with the decision.
Sinofsky, former president of Microsoft's Windows and Windows Live division, announced that he was
leaving the company
yesterday after a little over 23 years with the tech giant. It was reported as a "sudden" move that no one expected, but new details behind the departure show that the decision was contemplated for a while and even backed by Microsoft co-founder and chairman Bill Gates.
While Sinofsky was seen as a brilliant figure at Microsoft, his downfall was that he didn't get along with others within the company. He was notorious for picking fights with other executives, including current CEO Steve Ballmer, and even pushed former executives like chief software architect Ray Ozzie to quit.
Sinofsky was key to the development of Windows 8, which was
released October 26
and features an entirely new look and feel from the traditional Windows experience. However, Ballmer recognized that Microsoft needs to be more united internally across different divisions, and that change would be difficult with Sinofsky around.
Typically, in other company disputes, Ballmer and Gates would back up Sinofsky. But that doesn't seem to be the case this time around. Microsoft is looking to change and integrate teams across various units within the company. Ballmer saw Sinofsky as an obstacle to getting to that point, and
with Gates' support
, decided to part ways with Sinofsky.
All Things Digital
heard rumors about Sinofsky's departure over the last few weeks, both from inside and outside of Microsoft's walls.
While the decision to part ways with Sinofsky was a good thing in terms of moving Microsoft in a new direction, it also means the loss of a great mind that had a strong handle on Microsoft's software and innovation. Sinofsky may not be a team player, but he was great at what he did. Losing that sort of creativity and completely revamping the inner dynamic of how Microsoft's teams work will not be an easy task.
Julie Larson-Green, who has worked with Microsoft since 1993, is replacing Sinofsky. She played a key role in program management, and UI design/research for Windows 7 and Windows 8. So we'll see if Larson-Green can stand up to the challenge and fill Sinofsky's shoes while complying with the new integrated direction Microsoft is looking to take.
Sinofsky's leave is eerily similar to that of the recently departed
Scott Forstall
, Apple's former VP of iOS Software. Forstall was let go in late October after 15 years with Apple due to recent issues with iOS 6's maps and his tendency to not get along with other Apple execs.
remember me
This article is over a month old, voting and posting comments is disabled
RE: Sinofsky and Forstall should go make their own company!
Windows does have its moments of faults. Install a program like Adobe Flash plug-in can be a nightmare. Computer manufactures usually have it installed, but I found cases that it does not work. So it is best to uninstall it and download it from a reputable source. Well this not easy to do over the phone. Also using remote desktop can work, but that may not be easy to get it to work. The end result is best to work on that system in person to fix the issue.
There are other times that installing Windows programs are foreign. Why does a program need "something .NET" to be installed first and then the main program. Windows can be just as foreign to install programs like it is in Linux. I am a semi-software developer, I know why .NET is required for some programs, but other people does not.
Pre-compiled distributions are the worst way to try Linux. These type of distributions make sure the user does it the distribution way, but it may not be the correct way or safer way. There is no way to be certain that you are downloading a package from a reputable source. I have used Ubuntu and Linux Mint which show the worst of Linux multiple times. They make using proprietary drivers harder to use compared to other distributions like Gentoo. Also they do not correctly manage proprietary OpenGL libraries. They instead over write Xorg OpenGL libraries with the proprietary OpenGL libraries. Gentoo manages OpenGL libraries by separating them, so you can select which ones to use.
When I built my new computer last month and installed Linux, I did not have to configure anything from the command line. I installed Calculate Linux (a ready-made Gentoo based distribution). Setting up my network printer was easy through CUPS web interface. CUPS web interface is far more easier than setting up printers in Windows especially network printers. The time it took me to answer the questions that the Calculate Linux installer asked is about the same time to install Windows. After it booted in Linux, everything worked. I had to adjust sound card settings using alsamixer. There is a GUI program that comes with Xfce that acts like alsamixer, but I did not use that. I did install PulseAudio because I wanted more control for programs handling my sound card. The install process was straight forward from the gentoo-portage.org wiki page for installing and setting up PulseAudio. Then I got back doing what I stop an hour before, so I Linux gives me more time for other things that are non-computer related compared to Windows.
Linux does have GUI tools, but few distributions have it. Mandriva, PCLinuxOS, and Linux Mint has them. I think Linux Mint GUI tools are better because it has a an app-like store for installing applications.
"Spreading the rumors, it's very easy because the people who write about Apple want that story, and you can claim its credible because you spoke to someone at Apple." -- Investment guru Jim Cramer
Related Articles
Steven Sinofsky, Microsoft's Windows Chief, Leaves Abruptly
November 12, 2012, 10:11 PM
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October 29, 2012, 6:36 PM
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October 25, 2012, 5:47 PM
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October 22, 2012, 12:52 PM
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'The Great Gatsby': A to Z Leonardo DiCaprio
POSTED: 08:44 AM MDT Jun 15, 2011 UPDATED: 12:00 AM MST Dec 28, 2012
As "The Great Gatsby" opens in theaters, learn 26 fascinating facts about Leonardo DiCaprio right here.
The views expressed are not those of this company or its affiliated companies. Please note by clicking on "Post" you acknowledge that you have read the Terms Of Service and the comment you are posting is in compliance with such terms.blog comments powered by Disqus


text:
Click the link for daily surf reports presented by Nichols Surf Shop, 411 Flagler Ave., New Smyrna Beach
NEW SMYRNA BEACH – When Adele Aletti made the decision to move to New Smyrna Beach in 1988 to open a store on Flagler Avenue, she said she thought she had gone bonkers.
"Really, I did," she said Monday, remembering having second thoughts of "Oh, what have I done?"
Please click attachment to read NSB police patrols report:
Aug. 18, 1927 - Sept. 5, 2010
Dr. Bill Epps, age 83, of New Smyrna Beach, died Sunday at Hospice Care Center, Port Orange. Born in Sanford, Dr. Epps was a graduate of Georgia Military Academy, Stetson University, and Emory University Dental School. He practiced dentistry in both Sanford and Edgewater.


text:
Hot Links: Why are commuter trains crashing?
Here are the stories giving me chills on a hot Texas morning:
1. Another month, another mass-transit disaster: This latest one, which killed at least seven people in the nation's capital, was supposed to be impossible, The Washington Post reports. A computer should apply brakes automatically if trains get too close. Another mystery: The driver of the train that crashed had a clear line of sight but apparently never braked, either. Was she incapacitated? Using a cell phone, like the drivers I wrote about last month?
2. Another week, another higher-ed exec getting paid by taxpayers not to work: Tarrant County College Chancellor Leonardo de la Garza has quit with two years left on his contract — but still will receive $700,000, the Fort Worth Star-Telegram reports. The story lacks much context; go to the Fort Worth Weekly for that. Last week, Elsa Murano quit as Texas A&M boss. Here's her deal, as reported yesterday by my colleague Holly Hacker: "She will be on leave for a year and keep her president's $425,000 salary, plus an additional $295,000, and she agreed not to sue. She plans to return as a professor, at a $260,000 salary."
Do you have a tip about mass transit? Higher ed? Another subject? Send me an e-mail and let me know.


text:
Great for keeping small breeds or non-jumping pups out of off-limits areas, and it's short enough for you to step over easily. This gate has multiple uses, because it's portable and free standing. Perfect for when guests are over, to give cats their own canine-free zone, and to keep dogs out of the cat litter. Use it at bottom of stairs to keep dogs from getting up into bedrooms. The Step Over Gate is designed for small breeds, non- jumpers, and puppy litters. This wood gate is simple to set up and is operational in minutes. Rubber feet protect floors and add stability and can be permanently attached, if desired. Solid wood construction provides beauty. Gate height is 20" and it fits openings from 28" to 51-3/4". Add an extension (sold separately) to extend gate width 22" or more, depending on the number of extensions you add (add as many extensions as you like). Bar spacing is 2-1/4".
Please specify White, Oak, Walnut, or Natural (Extension not available in Natural).
Gate Dimensions:
Downloadable Cardinal Gates Step Over Wood Gate Assembly Instruction PDF.
Shop more Pet Gates.
Please click on "More Information" for installation instructions and cleaning.


text:
It's a pop-up book! It's a playground for your small pet! It's both! This cute wipe-clean, durable playground is perfect for small pets to interact with family - with climbing places and resting places, it looks just like an urban playground.
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Vaccinate your pet at Home and SAVE!
Watch 100s of expert How to's & reviews.
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*FREE economy ground shipping to 48 connecting states only on orders $19 or more. No promo code needed. See full shipping rates here.
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UNIVERSITY PARK -- Cory Giger and Neil Rudel discuss Penn State's 34-7 win over Navy, the first victory of the season and first of coach Bill O'Brien's head coaching career.
Article Video
Penn State 7, Navy 0: The Lions went 72 yards in only eight plays on their opening drive, highlighted by a 45-yard pass from Matt McGloin to Allen Robinson to set up first-and-goal at the 4. The Navy defender slipped on the play, so Robinson was wide open. Two plays later, McGloin scrambled to his right and found tight end Jesse James for a 2-yard TD with 11:25 left in the quarter.
Penn State 14, Navy 0: McGloin hit Robinson on a 45-yard TD strike on the fifth play of the next series. Robinson worked himself free down the left side, was wide open when he caught it, made one quick move and had smooth sailing to the end zone with 6:40 to go in the quarter. Navy put together a good drive on the ensuing series, getting inside the PSU 10, but quarterback Trey Miller was pressured by Sean Stanley and lofted an ill-advised pass that was intercepted by Gerald Hodges.
Penn State 20, Navy 0: The Lions started at their own 10 after the Hodges interception and continued to look impressive offensively with a 90-yard TD drive. Curtis Dukes did the early work on the ground, then McGloin stayed hot and picked apart Navy's secondary. He had a 19-yard pass to Robinson, a 7-yard pass to Paul Jones for his first career completion and showed good patience waiting for Brandon Moseby-Felder get open near the goal line on a 12-yard pass to the 2. McGloin found Robinson in the back of the end zone on the next play with 8:59 left in the half. Ficken missed the PAT wide right.
Penn State 27, Navy 0: The Lions were burned on a tipped pass that went for a TD in the opener against Ohio, and this time around they were the beneficiary of a similar play. McGloin tried to hit Trevor Williams down the middle, but the receiver tipped it, and the ball bounced right to Robinson in the end zone for a 25-yard score with 2:23 left in the quarter.
Penn State 34, Navy 0: Linebacker Mike Hull scooped up a fumble from Navy backup quarterback Keenan Reynolds and had nothing but green in front of him as he ran for a 74-yard TD with 14:13 remaining.
Penn State 34, Navy 7: Gee Gee Greene's 12-yard TD run, against mostly backup defenders, ended the Lions' shutout bid with 10:03 to play.


text: So apparently, it wasn't enough for Apple to innovate home computing, digital music and mobile technology. Sure, Apple TV has created a stronger connection between our monitors and the vast cloud of internet data, but this latest news could forever transform how we watch and interact with content in all forms. According to our friends at Patently Apple, the tech giant now has its sights set on virtual reality. Apple was granted a patent that details a way to literally connect people straight into their computers, using a mixture of touch screens, VR gloves and next generation sensor technology.


text:
Top Definition
Fun person,hott, usually a girl, very flirtatious, awesome personality.
every man needs a girl like Char.
von Guy Amos 29. Januar 2005
Trending Now
Can you define these popular missing words?
The Roman Goddess Of Blowjobs.
That Blowjob I Got Last Night Was So Good, It Felt Like It Was From Char Herself!
von MaddoggEros 12. April 2009
Char Aznable, character from the 1979 anime series Mobile Suit Gundam and its sequels, Mobile Suit Zeta Gundam and Mobile Suit Gundam - Char's Counterattack. Also known as the Red Comet.
Char took out five battleships at the Battle of Loum!
von ShadowCell 5. August 2005
A girl who avoids chores and cleaning duties
"Char hasn't done the washing up AGAIN!!!"
von Dan Blueugfsuge 19. Januar 2009
a cup of tea.
would you like a cup of char bill
von donsax 21. Dezember 2006
Nick name for a boy or girl.
Charlotte prefers to go by Char
von Char to the lottie 15. April 2006
A female that is partial to the 'bun' hairstyle on the very top of her head. That is, not the back of the head, but the very top, at the highest point hair can reach. This hairstyle is often accompanied with lazy-day clothes and no make-up, but exceptions are frequent for the mistaken few.
'did you see that girl's hair?' 'yeah, she must be a char'
von bunbrigade 2. November 2011


text:
Next Saturday ushers in the first wave of the small-game seasons here in Pennsylvania as hunters will head to the woods in pursuit of squirrels and grouse. In general, participation in small-game hunting has declined noticeably over the past 25 years or so, but each of these forest-dwelling species continues to attract their share of hunters each year.
Squirrels are often regarded as an "entry level" species because many first-time hunters are introduced to the sport by bagging a few squirrels. First, squirrels are not difficult to find. Almost any woodlot that includes a few oak or hickory trees will be likely to harbor an ample number of bushytails. Squirrels are typically quite active during the fall, diligently caching away nuts and other food items for the upcoming lean days of winter. Pick a comfortable spot in the squirrel woods and sit still. It usually won't be long before a squirrel or two makes an appearance.
The youth squirrel season began yesterday and runs through this Friday. Hunters from 12 to 16 who have completed a Hunter-Trapper Education course and are accompanied by an adult can participate in this special hunt and no hunting license is required. Kids under 12 are also eligible to participate in the youth squirrel hunt under the Mentored Youth Hunting Program.
My personal preference for hunting squirrels is with an accurate-shooting .22 or .17 HMR rifle topped with a good scope. With such a rig, I enjoy still-hunting many of the same spots where I also hunt deer, which allows me to do a little preseason deer scouting and bag a few squirrels in the process. The rifle-shooting practice is also a worthwhile tune-up for deer season as well.
Game Commission sources generally rate the northwest and northcentral regions of the state as the best areas for grouse right now. Here in the southcentral region, the overall outlook for grouse is rated as fair.
"Conditions for over-wintering, incubating and brooding should have supported good reproduction this year," said Lisa Williams, Game Commission grouse and woodcock biologist. "However, our Game Commission field staff observed fewer adult grouse and grouse broods this summer compared to prior years. Those sightings are often the best predictor of the season, so I advise hunters to hope for the best but keep their expectations realistic. Find areas of good dense cover and abundant food supply and you'll put yourself in the best position for success."
Of course, most experienced grouse hunters know there are always a few spots that seem to attract or hold a few birds even in lean years. Such special grouse covers have usually been discovered over the course of many seasons and represent countless hours of tramping about the ridges and hollows each fall. As you might suspect, such grouse hotspots justifiably will be closely guarded secrets, so if a grouse fanatic offers to share one of his favorite covers with you, realize how special that is.
In spite of the less-than-optimistic forecasts for grouse hunting this season, one thing grouse hunters have going for them now is much less competition from other hunters compared to just a couple of decades ago. According to Game Commission estimates, Pennsylvania had about 400,000 grouse hunters during the mid-1980s; currently, that number is now just 80,000.
The Game Commission has conducted a Grouse Cooperator Survey for many years using volunteer grouse and woodcock hunters to monitor such things as hunter effort, flush rates and number of birds bagged. The data provided by the survey participants helps the agency to examine population trends and other vital information about these game birds. Grouse and woodcock hunters of all skill levels are encouraged to participate in the survey regardless of how many days they hunt grouse or woodcock during the season. Participating hunters will be asked to record the county and number of hours hunted, and number of grouse and woodcock flushed and bagged.
If you are interested in participating in the Grouse Cooperator Survey, contact the Pennsylvania Game Commission's Bureau of Wildlife Management at 717-787-5529, or by writing to: Pennsylvania Game Commission, ATTN: Grouse Cooperator Survey, 2001 Elmerton Ave., Harrisburg, PA 17110-9797. New Cooperators will receive a copy of the annual newsletter provided to all survey participants and all forms needed for the upcoming season.


text:
Some water providers, cities, and utility companies give away free showerheads as part of their conservation program.
For information about showerhead incentive programs in your area, contact your local water provider.
These Niagara Conservation products are an example of conservation kits distributed by local cities or water providers. Photo source: City of Roanoke, VA Accessed September 5, 2003, by permission.


text:
MARTINSBURG - The jury in the trial of a Bunker Hill couple accused of abusing five children under their care has reached a verdict in the case following 11 days of proceedings.
The jury of nine men and three women returned with a verdict shortly after 2 p.m. this afternoon.
The jury found Nathan A. Snyder, 29, of Nereid Lane, guilty of four counts of felony child abuse causing bodily injury and not guilty on eight remaining counts of an indictment charging him with child abuse causing bodily injury. He was originally indicted in February 2010 on 13 counts of child abuse causing injury, but one of the counts was dismissed during the trial last week.
Article Photos
Nathan Snyder
A co-defendant in the case, Christina A. Snyder, also of Nereid Lane, was found not guilty on one count of felony child abuse causing bodily injury and guilty on a lesser included offense of misdemeanor domestic battery on the remaining count of child abuse she was being tried on. She was originally indicted on five counts of child abuse causing bodily injury, but three of the counts were dismissed last week. She is scheduled to be sentenced April 11 by West Virginia 23rd Judicial Circuit Judge John Yoder.
The state, represented by Berkeley County Prosecutor Pamela Games-Neely, immediately filed a recidivist information against Nathan Snyder following his convictions, alleging he has two prior felony convictions. Under West Virginias three strikes rule, he now could see his sentence enhanced to life in prison on one of the felony counts he was convicted of. No sentencing date has been scheduled in his case. That will take place after a separate recidivist trial that has been scheduled for April 23.
"We are satisfied with the verdict in this regard. It was a long and very hard-fought case. It shows us that child abuse happens in silence in many respects. I admire these children for how far they've come in this respect, and I thought that the verdict, based on all the evidence that the jury heard, was fair," Games-Neely said.
Christina Snyder's attorney, Christopher Prezioso, thanked the jury for their time.
"I just want to thank the jury for their hard work, and we are disappointed, obviously, with the misdemeanor conviction, but we're extremely happy that she was acquitted of all the felony counts," Prezioso said.
Nathan Snyders attorney, Thomas Stanley, said he was shocked by the verdict.
"My first comment is I can't believe the jury found him guilty of anything based on the evidence I heard. I am totally shocked by the verdict, and I'm sure there will be an appeal," Stanley said.


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Top Definition
A feeling of minor fright, anxiety, nervousness, apprehension, "the willies", phobic
That spider crawling on my neck gave me the heebie jeebies
by alphachimp October 11, 2003
Trending Now
Can you define these popular missing words?
the creeps
this place gives me the heebie jeebies
by Zoey October 11, 2003
1. Noun: The physical and psychic reaction to something revolting or disgusting. May be expressed in a shiver, shudder, or the archtypal skin crawling.
2. Noun: The fear response to something perceived as paranormal. Being spooked or creeped out.
2. Noun: The fear response to something perceived as paranormal. Being spooked or creeped out.
When I first heard about Total Information Awareness, I got the heebie jeebies.
by kiddo October 08, 2003
The feeling of shivers down your spine, or the hair on the back of your neck rising. Usually used in reference to something scary (common usage), but can also be used in reference to something gross or stomach-churning (rare usage).
Walking through the cemetary at night gives me the heebie-jeebies.
by Msquared May 26, 2003
A sensation one feels when they enter a scarey situation with unknown consequences.
The kids all got the heebie jeebies as they entered the old haunted mansion on a Halloween dare.
by Lonni Jobe October 13, 2003
A passe term used to refer to a feeling of being 'freaked out'.
The thought of George Bush being president of America gives me the heebie jeebies.
by Stuart October 11, 2003
scared as hell
Man....spiders give me the heebie jeebies!
by The Crack Jackal October 12, 2003


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As Immunotherapy Revolutionizes the Cancer Treatment...
LC-MS Gains Favor Due To the...
NSCLC is "Major Battlefield" as Merck,...
Developers of DTC Genetic Testing Are...
FDA recommends that diagnostic manufacturers meet with agency professionals early in the development cycle to make sure development plans are in line with protocols. [©Radu Razvan_Fotolia.com]
The mapping of the human genome, completed in 2003, launched a new era marked by growth in the development of diagnostic tests designed for use with new drugs. As of 2009, some 40 drugs were accompanied by these companion tests.
Now FDA is weighing in, saying it wants to assure patients that the companion diagnostics are as safe and effective as the drugs that they accompany. On July 14, the agency issued a draft guidance designed to inform companies about the agency's policy for reviewing companion diagnostics and their corresponding therapy.
FDA's "Draft Guidance for Industry and Food and Drug Administration Staff - In Vitro Companion Diagnostic Devices" recommends that diagnostic manufacturers meet with agency professionals early in their development process to ensure that FDA's expectations are included in development plans. The draft guidance also emphasizes FDA's intent to review drugs and their corresponding companion diagnostics simultaneously.
The proposed rule also identifies instances where the FDA may approve a targeted medicine in the absence of a cleared companion diagnostic—namely in cases where a therapy is intended to treat a serious or life-threatening disease for which there is no "available or satisfactory treatment" as well as cases when the potential benefits are deemed by the agency to outweigh the risks of not having an approved companion diagnostic. In such cases, according to FDA, the therapy could be approved first while the companion diagnostic may be sanctioned later.
FDA "strongly encourages sponsors to time their clinical developments and premarket submissions to facilitate concurrent approval," according to the draft guidance. "We are not looking to slow down development. Rather we believe that if stakeholders understand the regulatory requirements, development and approval will be sped up," Elizabeth Mansfield, Ph.D., director, personalized medicine in the Office of In Vitro Diagnostics in FDA's Center for Devices and Radiological Health, told GEN.
Dr. Mansfield said the draft guidance does not signify a change by FDA in how it plans to regulate companion diagnostic devices going forward: "We are not expecting to change our approach. This guidance is intended to let stakeholders know what our favored approach is so that their expectations are matched to the regulatory approach."
FDA had sought to issue guidelines addressing aspects of drug/diagnostic co-development since 2005, when the agency issued a concept paper outlining its initial thinking on the topic. That effort was criticized by both pharmaceutical firms and test makers, both of which felt the agency's proposed guidelines failed to account for the challenges of aligning competing interests, different development timelines, and divergent regulatory pathways for therapeutics and diagnostics.
Harry Glorikian, managing partner with Scientia Advisors, cautions that if the FDA ultimately requires that a diagnostic be approved and in kit form before a drug is approved, that test has to be ready for use before Phase III trials, since the FDA must be able to look at data in which patients are stratified using the exact same technology in clinical trials that will be used once the drug is on the market.
"This implies that there will be an even greater hurdle to drugs being developed for launch with a companion diagnostic, and pharma companies will be even more reluctant to take this path," Glorikian told GEN. "Ultimately, it will result in a net increase in the time and cost of drug development."
Diagnostic companies may find it much harder to develop joint programs with pharma partners. They may no longer consider providing a better test after a drug is launched as a viable business model. Additionally, diagnostic firms will be required to codify all technical features into a kit, potentially limiting diagnostic innovation.
Not all industry observers share that sentiment. "We view the new draft guidance as a clear indication of FDA's interest in streamlining the approval process for companion diagnostics," concluded Brian Marckx, an analyst with Zacks Equity Research, in a report.
Also weighing in on FDA's draft guidance is the Personalized Medicine Coalition (PMC), an umbrella organization that represents more than 200 academic, industry, patient, provider, and payer communities. Amy M. Miller, Ph.D., PMC's public policy director, told GEN that the draft guidance provides clarity on FDA's current thinking on regulating companion diagnostics, long a source of concern to the drug and device industries.
In its draft guidance, FDA envisions collaboration between its drug and device centers but does not offer specifics. "There's very little detail about how that's going to actually work. If that works well, it will speed up clearance of these products. But if that does not work well, it could slow it down," Dr. Miller pointed out.
In its 2009 report "The Case for Personalized Medicine," PMC said more than 1,300 genetic tests exist that signal inherited susceptibility to a wide range of conditions: "While not every test has a therapeutic option, a genetic diagnosis often permits targeted prevention or mitigation strategies." Dr. Miller said the report is being updated, with the new edition—including new data—set to be published in the fall.
Sometimes, even simultaneous approval of a drug and its companion diagnostic is no guarantee that problems won't arise later. In 2009, FDA updated the labeling for two colorectal therapies already on the market, Vectibix (Amgen) and Erbitux (Eli Lilly and subsidiary ImClone), to inform doctors that patients with KRAS mutations would not respond to these drugs.
Vectibix and Erbitux are anti-epidermal growth factor receptor (EGFR) antibodies approved at the same time with their original companion diagnostic, developed by partnering with Danish firm DAKO. But evidence that KRAS mutation status would affect how subjects responded to anti-EGFR treatments became apparent only after the decisive clinical trials for these antibodies were conducted. Amgen and Imclone analyzed the existing retrospective information, finding that about 43% of patients—those with KRAS mutations—did not respond to the EGRF inhibitors.
Qiagen's DxS subsidiary later signed agreements with both drug companies to develop a KRAS companion test for Vectibix and Erbitux and pursue approvals from FDA for those tests along with the drug developers. FDA to date has yet to approve Qiagen's KRAS test. In the meantime, a number of laboratories are marketing tests that detect KRAS mutations but have not been cleared through the agency.
Concurrent Dx/Rx reviews have the potential to bring promising new drugs and their companion diagnostics to market faster. But for that to happen, drug and diagnostics companies will need to consult with FDA earlier in the development process.
Just as diagnostic firms will have to work closely with drug developers, so will the drug and device centers at the FDA. How much progress is made toward goals set by the agency will determine how effective the concurrent Dx/Rx review process telegraphed by FDA in its Draft Guidance will be in bringing life-saving therapeutics and diagnostics to the patients who need them.
Alex Philippidis is senior news editor at Genetic Engineering & Biotechnology News.
Alex Philippidis is senior news editor at Genetic Engineering & Biotechnology News.
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If you lost 18% of your income would you be happy? I can honestly say that I am more stressed about money now then when I was in college.
I can't explain it and I never thought it would be the case but it is true. $ in no way makes u more happy or makes life much easier.
If you don't make a lot of money I don't expect u to understand in the same way I could never understand what it is like to risk my life
Daily as a fire fighter or police officer...especially not a soldier. There r pros and cons to every profession. U r kidding yourself..
I even gave you all ample warning and you still bit...when are going to learn to not take me seriously? Some of u got really pissed
Simple solution to the sensitive=unfollow! I am not holding a gun at your head to follow so do yourself a favor
From now on I will just tweet stuff like...driving to rink...drinking coffee...watching TV. That will be fun to read?!?
... [later on] ...
Ppl r still replying about somethin I tweeted an hour ago. U realize twitter is just a silly way to communicate and not b taken as gospel?
This has spawned a #DanEllisProblems hashtag with lots of fun.
Edited by CaliWingsNut, 07 September 2010 - 01:31 AM.


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Evelyn Trammell Institute for Voice and Swallowing
|related articles
|In-Office Treatment of Radiation Fibrosis or True Vocal Folds
|Lucinda Halstead, M.D.
Released: 02/04/2014
|Beyond the Modified Barium Swallow: Alternative and Complimentary Instrumental Assessments of Swallowing
Ashli K. O'Rourke, M.D.
Released: 04/02/2013
Standardized Measurement and Modeling Oropharyngeal Swallowing Impairment
Bonnie Martin-Harris, Ph.D.,
Released: 02/05/2013
Under the direction of Dr. Bonnie Martin-Harris and Dr. Lucinda Halstead, the Evelyn Trammell Institute for Voice & Swallowing offers comprehensive management for patients with voice and swallowing disorders. Our multidisciplinary approach integrates expertise in the diagnosis and treatment of voice and swallowing disorders with clinical research to optimize patient outcomes. Committed to evidence-based practice and providing the highest level of patient care for adults and children, the Institute addresses the following types of conditions relating to the voice and swallowing mechanism: Meet our team members!
Communication and Voice Disorders
- Vocal misuse and overuse
- Recurrent and chronic laryngitis
- Vocal cord growths
- Spasmodic dysphonia
- Paradoxical vocal cord dysfunction
- Vocal cord weakness and paralysis
- Aging voice
- Trauma and neurologic disorders
- Developmental speech and language conditions
- Professional voice users
- Alaryngeal voice prosthetics
- Neurogenic motor speech
- Neurogenic language and cognitive disorders
- Passy Muir valves
Specialized Voice Services
- Perceptual, acoustic aerodynamic assessments
- Laryngeal and vocal tract imaging/stroboscopy
- Laryngeal electromyography
- Pulse Dye laser surgery
- Laryngoplasty
- Laryngeal botox
- Voice therapy
- Comprehensive management team for professional voice users (Laryngologist, Speech Pathologist, Singing Voice Specialist)
Swallowing and Feeding Disorders (Dysphagia)
- Head and neck cancer
- Neurologic conditions
- Connective tissue disorders
- Pulmonary disease
- Congenital anomalies
- Tracheostomy and ventilator-dependent patients
Specialized Swallowing Services
- Videofluoroscopy
- Fiberoptiv endoscopy
- Transnasal esophagoscopy
- Oropharyngeal manometry
- Electromyography
- Swallowing rehabilitation
Return to Clinical Expertise..


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Active Birth Yoga for Pregnancy will continue on Fridays from September.
To register for prenatal yoga classes, please contact Sophie Girard-Sequeira directly at info[at]sophieyoga.net
More info on www.sophieyoga.net
Schedule 2016 - 2017
Trial a class for free !
10:00 – 11:00 (Yoga pour Enfants 4–7 ans) FRANCAIS
11:30 – 12:30 (Yoga pour Enfants 8–11 ans) FRANCAIS
- Semester 1 -
September 24
October 1 - 8 - 15 - 22 - 29
November 12 - 19 - 26
December 3 - 10
January 7 - 14 - 21 - 28
- Semester 2 -
dates TBC
16:00 - 17:30 Yoga For Teens (age 12-16) MULTILINGUAL
September 25
October 2 - 9 - 16 - 23 - 30
November 13 - 20 - 27
December 4 - 11
January 8 - 15 - 22 - 29
Sampoorna Yoga - developed by Shri Yogi Hari - is a traditional style of yoga in the Sivananda lineage.
The timeless Sampoorna Yoga can be practiced by anyone regardless of age, health and level of fitness.
1. It's adviced not to eat at least 2 hours before practice
2. Arrive early 15 minutes before class to give yourself a relaxed start. Doors close a few minutes before the start of class
3. Avoid wearing strong perfume. This interferes with breathing exercises, and some people are sensitive to smells
4. Please leave your shoes at the entrance
4. Please first pass by the reception to settle your payment (or have your yoga pass checked)
5. Doors will be locked during class, so you can leave your personal items in the dressing room
6. Enter the yoga room in silence, lie in Savasana or sit quietly until class begins
7. Inform the teacher of any physical injuries, medical conditions or pregnancy. In the event of any serious condition, please consult your doctor before beginning a yoga practice
8. Avoid drinking water during class. We attempt to create heat iin the body, while water has a cooling effect. After the class, drink plenty of water or tea.
If you have a question which isn't listed below, just call and ask !
1. Do I need to bring a yoga mat ?
If you have one, bring it. If not, we have yoga mats at your disposal.
2. What do I wear for yoga practice ?
Loose, comfortable clothes. Bring a sweater and warm socks to keep warm during relaxation.
3. I'm not flexible. Can I do yoga ?
Everybody can do yoga. No need to be flexible.
4. Can I put my bicycle inside the studio ?
Sorry, no room. You'll have to leave it outside. Make sure to have a good lock.
5. Can I park my car in the parking next to the studio ?
The parking next to the studio is private and not ours. You need to find a place in the street or in one of the Q-Parks close by.
6. I'm a beginner. Can I join an All Levels class ?
Yes. We do suggest though that you participate in a series of Beginners Classes first to feel more comfortable with the poses.
7. In which language are the classes given ?
All classes are in English.
© 2011 Sampoorna Yoga Studio | FAQ


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Ball State Women's Golfers at Indiana PGA Open
Rachael Pruett, a Ball State women's golf alum and the graduate assistant coach for the Cardinals, tied for third at the Indiana PGA Women's Open at Hickory Sticks Golf Club.
Pruett managed a 71-73=144 to finish three strokes behind the winner, Kristi Caldwell of Kokomo, Ind.
Meghan Perry, who will be a junior on the Ball State women's golf team this fall, tallied a 77-76=153 to tie for 22nd, with teammate and senior to be Autumn Duke, who tallied a 78-75=153.
The field included 100 players in the two-day stroke competition.


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Enjoy our award-winning service and benefits like complimentary onboard catering on direct flights to Stuttgart.
Flights to Stuttgart
from: £46 each-way au départ de: London, Nov 2016Réserver
Trouvez un vol British Airways moins cher, nous remboursons la différence.
Outil de recherche de petits prix et faibles dépôts initiaux.
Ensure your next holiday is extra special by talking to one of our European travel specialists.
5 £ de frais de réservation par personne sont facturés pour les réservations effectuées par téléphone.
Empruntez un vol British Airways pour profiter d'un service primé et d'un excellent rapport qualité/prix, sans aucun frais caché :
Enjoy our award-winning service and benefits like complimentary onboard catering on direct flights to Stuttgart.
from: £46 each-way au départ de: London, Nov 2016Réserver
Fly to Stuttgart direct from the UK and explore one of Germany's most attractive, cultured cities. Regular British Airways flights to Stuttgart help create a schedule that suits you.
Stuttgart's combination of high culture with easy living make a city break here more relaxing than most, the city priding itself on being more laid-back than its north German counterparts. Stuttgart is also a gateway for the Black Forest, whose wooded mountains begin less than an hour from the airport.
Flights from London Heathrow to Stuttgart Airport take 1 hour, 35 minutes. With many regular flights to choose from, planning a Stuttgart holiday has never been easier.
Fly non-stop to Stuttgart from London Heathrow and enjoy a city break with a difference. Regular flights make it easy to find a travel time that suit you. Choose to fly with hand baggage only or pick a price that includes a 23kg checked baggage allowance and free seat selection 24 hours before you fly - both options include complimentary on-board drinks and snacks.
Stuttgart airport lies 8 miles (13 kilometres) south of the city. It is connected to central Stuttgart by the S Bahn rail line, which takes less than 30 minutes to reach the city's central station. Public transport links within Stuttgart are excellent. The city's network includes not just the Stadtbahn light railway system, but also an unusual rack railway designed to scale Stuttgart's hills.
Stuttgart's airport may be compact, but its shops and restaurants are very good. Its Top Air restaurant is one of the few airport restaurants to earn a Michelin star, while beyond security control, its Pasta and Seafood Trattoria sells good Italian cooking with runway views. Extensive duty free shopping is on offer in the departure lounge.


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Providence Public Library is an essential agency of public education and crucial to the infrastructure of the Rhode Island community. We are one of the few major libraries in the United States that is a private not-for-profit institution governed by a Board of Directors, giving us the flexibility to respond to community need rapidly and effectively. More...
Interested in holding
your special event at
Providence Public Library?
Call today...401.455.8072View Library Spaces
Tour our historic Library online.
Wednesday, January 1, 2014
View the story
of our 115-year-old
Library's restoration.
Providence Public Library... Building for the Ages
Historic building tours - 1st & 3rd Tuesdays!
Remembering when...
Marching in Providence!
City Hall
PPL Special Collections - Glass Negatives
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Browse our
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Kerry Tobin wrote in another thread: "on the other hand, I never would have believed there would be two different murders in one year in my lifetime."
Kerry, go to the newspaper archives. There was a year in which there were 4 murders, maybe 5. I still lived in Tomahawk. I want to say it was about 1987. Two people, a husband and wife, were murdered in Irma. The murderer was caught, he was a drug addict. I believe he was from Tomahawk. The same year a man was murdered by his wife or girlfriend's boyfriend or husband. It was one of those messy domestic situations. The same year a man was murdered in Tomahawk by his wife. I'd have to get my diaries out to check dates. I remember some of the families involved but do not want to use them on a public board. I'm sure others remember the cases I'm talking about. And I vaguely remember a 5th murder.
Murder is always tragic, but it isn't anything new, sadly.


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The Big Man - Clarence Clemons, of Bruce Springsteen and The E Street Band fame, and Temple of Soul live at the Stone Pony!
Clarence Clemons - Temple of Soul: Live in Asbury Park, Volume 2 featuring his biggest hit single "You're a Friend of Mine" and "Raise Your Hand" with Bruce Springsteen on lead vocals and lead guitar.
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For wholesale inquiries or license requests, please call 212-580-9200 ext. 15 or email firstname.lastname@example.com


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Top Definition
A group of Mexican women stacked on top of each other, covered in taco sauce and chili peppers. A guy then proceeds to individually ass-rape each girl with a nacho-cheese covered dick.
Dude, I went to Sanchez's party, there was a Spanish Escalator going on.
Beküldő: E.E. Atbls 2009. május 28.
Trending Now
Can you define these popular missing words?


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U.S. hawks dead wrong on Syria war
June 22, 2013
There are at least two schools of thought regarding President Barack Obama's conduct of U.S. foreign policy. One holds that he knows what he's doing....
This ignorant President Obama is getting us into a mess WORSE than IRAQ and it will take us a long time and the Republicans to get us out!!
I thought Obama and democrats hated wars? It appears they love them moreso than Bush or any other politician on the right as Obama keeps getting us involved in more and more every year. What an inept, clueless, dangerous president the people voted for. Le'ts hope he does no more damage before he's finished his term. Still cannot figure out WHY he's not already been impeached. THAT is a question I'd like answered!!
3 Agrees | 1 Disagrees | Report Abuse »
Obama Administration is INDEED the STUPIDEST bunch of clowns I've ever seen in my lifetime!
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For Businesses
Business Information
Westminster College through its Community Relations department seeks to establish a mutually beneficial relationship between student, employers and the college. The responsibilities of each participant are listed here:
· Work with community relations department in creating a project scope document prior to student starting.
· Report monthly or as needed via email on project progress to Westminster's Community Relations department.
· Report any concerns or successes to Westminster's Community Relations department
· Ensure the student is having a valuable applied learning experience by ensuring student works on project scope.
· Work with student providing feedback, documents and data necessary to complete project.
· Complete Program Evaluation after completion of project.
If you believe your business could benefit from the Westminster Student Consultant Program, fill out the application here to be considered.


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Beyond Mickey Mouse, Universal and the miles of beaches are several other interesting and odd tourist attractions that make Florida famous. It's time to hit the road and check out a few.
List: Odd Florida tourist attractionsUPDATED 9:40 AM EDT Aug 07, 2014
Slideshow Central
CommentsThe views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use.blog comments powered by Disqus


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Turn heads with Perfect 10—the high-gloss colour that delivers expert-level results in just 10 minutes. This salon-inspired crème formula with shine-activating Micropearls drenches hair with luxurious colour and shine that lasts up to 60 days.
Only Nice 'n Easy has Color Blend Technology, which gives every shade built-in tones and highlights. Whether you choose our original or foam formula, you'll enjoy lasting, dimensional colour and complete grey coverage in a single step.
Find a shade you'll love to bring out the most beautiful you. Select a shade to start exploring.
The original shade you selected is in the center here, surrounded by one shade darker, one shade lighter, a warmer shade, and a cooler shade. Click any of them to return to the product page.
This Root Touch-Up shade works with any of these brands
Choose your brand and shade to see your perfect Root Touch-Up match.
Download and print the Entire Shade Chart
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Other views - Click on image to change view
Perfect 10
by Nice 'n Easy
Starting colour
Resulting colour
SIMPLE STEPS TO STUNNING colour
Follow these simple step by step instructions to get a designer colour in just 10 minutes!
If any colour gets on your skin or a household surface, wipe it off immediately with a damp towel.
THE SCIENCE OF PERFECT 10 HAIR colour
ADVANCED TECHNOLOGY. AMAZING HAIR colour.
An advanced colour creme formula with micropearls delivers colour in less time* and it gives you high-gloss haircolour with flawless grey coverage.
This technology is the biggest advance in haircolour in 50 years—it has 18 patents applied for and received the Royal Society of Chemistry Teamwork in Innovation Award. And it created the one and only Perfect 10.
Perfect 10 was the first product to use Clairol's advance colour creme formula, which works so efficiently that it does the job in just 10 minutes. The advanced colour creme with micropearls allows for fast penetration into the hair fibers.
Once inside the hair, the combination of effective ingredients targets the natural melanin pigment and deposits the new colour. The complete colouring process is accelerated and we can achieve high-gloss colour and 100% grey coverage in 10 minutes.
Micropearls are the colour molecules that exist within Perfect 10's advanced colour creme formula. Each shade of Perfect 10 contains a mix of different coloured molecules and conditioning ingredients to create the desired shade. Perfect 10's advanced colour creme with micropearls is what provides consumers with high-gloss colour in just 10 minutes.
Perfect 10 uses a combination of new elements that makes it so exciting. It uses a lightening system—which is the heart of any colourant—to prepare the hair and speed up the colour reaction, energizing colour to move inside the hair, creating beautiful, high-gloss colour in just 10 minutes. This is just a reason why Perfect 10 was one of the biggest colour breakthroughs in over 50 years.
Absolutely not! Interestingly, when we developed Perfect 10, our first objective was to create a "better" haircolourant—and along the way we realized the new technology was so good that it could do the job in just 10 minutes. Some other 10-minute products use existing, technology—just changed a bit to give faster results. This is very different from the approach we took with Perfect 10.
Perfect 10 is less damaging* to the hair surface because of its unique advanced colour creme formula. Its active ingredients work best at a lower, gentler pH than most colourants, so Perfect 10 better preserves hair's natural protective coating called the f-layer. In addition, we have shown that the advanced colour creme reacts more selectively with the pigments inside the hair than with the hair itself, causing less surface damage*. On top of that, the ingredient glycine, which is an essential amino acid and one of the fundamental building blocks of hair, works as an antioxidant, reducing the effect of free radicals formed during colouring. And last but not least, Perfect 10's weekly colourSeal treatment helps protect hair, keeping it smooth and soft.
The development of the Perfectcolour Comb was based on feedback from our consumers who struggled with the traditional colour applicators. It is designed to envelop each strand of hair in the rich colour creme from root to tip for even colour results and flawless grey coverage. The comb has 14 outlets to provide optimum colour distribution—five at the tip of each nozzle, five halfway down each nozzle and four at the bottom between the nozzles. This ensures even coverage regardless of the length or thickness of the user's hair.
Perfect 10 owes its great scent to our formulators and fragrance artists. The formulators invented a highly efficient colour technology, which works at a lower pH and therefore contains less free ammonia than some other products. Ammonia is the ingredient responsible for the harsh smell of many colourants. In addition, our fragrance artists created a scent that not only masks the remaining colourant odor but is also based on the same principles as a fine fragrance product and has beautiful top, body and base notes.
A lot of work has gone into making sure that each shade of Perfect 10 matches the colour results shown on the box. First, the shades were tested repeatedly in our salons on consumers to confirm just the right colour results. Then, hundreds of natural hair samples of appropriate starting colours were treated with Perfect 10 in our colour development labs and analyzed. The technical colour readings were then translated into on-pack images. Latest imaging and software programs have turned this work into a truly high-tech process because we know how important it is for our consumers to get exactly the haircolour they expect.
Perfect 10 gives shiny, glossy hair in several ways. First, it deposits high-intensity colour deep inside the hair fiber, leading to more intense light interactions—visible as shine. Second, it works at a lower, gentler pH with an antioxidant, reducing the effect of free radicals formed during colouring and better protecting the hair surface. A smooth, intact surface is shinier than a rough, broken one. Third, Perfect 10 uses a dual conditioning system with the colour creme and the weekly colourSeal treatment, allowing the hair fibers to be more aligned and reflect light better.
see our ingredients
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perfect 10 continues to win acclaim
Since its debut in 2008, Perfect 10 has won the admiration of beauty insiders. It's received 13 beauty awards, including the Allure Editor's Choice for 2010. Other honors include accolades from InStyle, Shape, and Better Homes & Gardens, as well as the coveted Cosmetic Executive Women (CEW) Beauty Awards.
Perfect 10 NewBeauty, 2011
Perfect 10 InStyle, 2009
Perfect 10 Star, 2009
"For an 'easy to apply and super-fast formula,' you choose Clairol Nice 'n Easy Perfect 10." —Elle
"[Perfect 10] causes much, much less damage to your hair than traditional colour—leaving you with shine and bounce to spare."—Jean Godfrey June,Lucky Beauty Director
"[Perfect 10] works in 10 minutes!"—InStyle
"Clairol Perfect 10 Nice 'n Easy gave to-dye-for results." —Brides
"Perfect 10 by Nice 'n Easy has a comb-topped bottle to coat every strand with permanent colour in 24 shades." —Didi Gluck, Real Simple Beauty Director
© 2014 Procter & Gamble. All rights reserved. All copy and claims valid only in the US.


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Tuesday, July 9, 2013
The Moultrie News' sports reporter Tyler Heffernan was honored last month with a Certificate of Appreciation and a special coin from Lt. Col. Ed Chamberlayne, district commander of U.S. Army Corps of Engineers, Charleston District.
He was issued the commendation for outstanding reporting of the news of the Army Corps of Engineers throughout the year.
He has reported on the Charleston District's highly visible Charleston Harbor Post 45 Deepening Study and the district's complex regulatory program.
The award said that Heffernan had the knack of taking technical nature of the Corp's projects and turning them into easy to understand news stories for the public. "He is a gifted writer who is accurate and fair and always captures the story for the reader. Heffernan covers local sports and island news in addition to his blog and regular column Eye of the Tyler. July 9 marked his one-year anniversary with the Moultrie News.
"It is an honor and a privilege to work with someone as talented as Tyler. "The local sports community has benefitted greatly from his in-depth coverage of not just scores and stand-outs but the stories behind the sports and the teams," said Moultrie News Editor Sully Witte.
"He has taken our social media outreach to a whole new level and continues to improve the overall standing of the company and the publication in our community. I am very proud to call him a colleague." Vickey Boyd, Publisher of the Moultrie News said Heffernan joined the Moultrie News team and never missed a beat. "It was as if he had always been with the paper. He set out and started meeting coaches and players and getting out in the community. And before we could blink he was the sports news source for East Cooper. He has grown our digital presence with web, Facebook and Twitter. My personal favorites by Tyler is the first person articles because he shows such emotion in his writing when it not an outright news story. Tyler has become an important part of our team and we are proud to have him on our staff."
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Thursday, February 7, 2013
Jim and I may not have had any Valentine's Day memories at all if it
weren't for that first date -- which almost wasn't. But on the 14th we will have
celebrated 59 of these occasions together. Well, almost together. It started
when we were courting in 1953. We've observed this special day along the
Atlantic and Pacific coasts a well as in the Midwest . We've exchanged heart-
inspired cards in the south and in the north as well as in Europe, and even
when we were separated – such as when the Air Force sent him to Iceland and
Viet Nam, or he was sitting alert or away on TDY (Temporary Duty).
We met on a train travelling from Illinois to Georgia for Christmas break.
Most of us spent the journey in the club car getting acquainted and singing
carols. I spent all that time sharing a red leather booth with this really neat
guy. When we reached Atlanta I got off and he went on to Augusta. We
shook hands and he said those three little words this college freshman wanted
so much to hear: "I'll call you."
Of course, back on campus, I told my college friends all about this brief
encounter and we all waited for "the call." I lived on my dorm's fourth floor
with a couple dozen other students, all sharing two hall phones. Every time it
rang there was a stampede to answer and the air vibrated with shouts
summoning the recipients.
Finally! My name was called and about a dozen classmates followed me
to the phone saying "This is it. This has to be it!" When I picked up the
receiver they encircled me, clasping hands and bobbing up and down. It was
him! I gave them the thumbs up and they signaled a touchdown. They all
hovered, eavesdropping and wanting to get the news first.
"Well," said my caller, "can you go out Saturday night?" Could I! But I
restrained myself from that enthusiastic response and allowed as how – in
what I hoped was an offhand casual reply -- that it just might be possible.
"Good!" he said, "Would you like to go to the basketball game and the dance –
with my roommate?"
As my heart sank, I fully understood the meaning of the term "dull thud."
Then I stuttered and stammered maturely while he added blithely, "Well I
already had this date but I thought we could double – and you'll really like Bill
– and then we could spend a little time together." I didn't know whether I
wanted to hit him or hug him.
But after all, he was tall and handsome. And after all I really didn't have
plans. So, after all, I mumbled "yes." My friends, of course, were aghast
and offered 12 different opinions of what I should have said and done – some of
them not exactly Christian.
Then two days later he called again and said would I mind going out with
him after all as he and his date had a fight and they cancelled out. He also
cancelled Bill out. This was in January. By February 14th we were a steady
couple and by summer, were engaged. We savor these memories every year at
this time. Try reminiscing next week with that special someone about how you
It really gives Cupid's arrow an even better target.
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Reviewed By Alexandr G (Milton, PA) Reviewed for a 2006 Acura TSX —3/10/2016 8:04 AM
Brembo rotors works very good, breaking twice faster then stock. Highly recommended
Reviewed By Jesus M (GLENDALE, AZ) Reviewed for a 1995 Acura Integra —6/28/2013 12:05 PM
Installed on a 95 integra sedan making 357whp 379wtq, they have great stopping power over own with ebc green stuff pads, minimal dust but they do make some noise, not too much. I used them before for track and they were awsome with the environment yellow stuff. Overall for daily driving I would stick with oem and some posi quiet pads.


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Search on for drivers after pedestrian struck, killed in Daytona Beach
FHP looks into crash on U.S. Highway 92 near Interstate 4
UPDATED 1:47 PM EST Jan 25, 2013
A woman lost her life when she was struck by multiple vehicles along International Speedway Boulevard early Friday morning.
The crash happened near Interstate 4 in the overnight hours.
The woman, later identified as Bridgett Davis of Hawthorne, Fla., was thrown into the roadway after she was first struck. That driver stopped. She was then hit by at least two more vehicles. Those drivers did not stop.
Florida Highway Patrol troopers said they have evidence from those vehicles and will be looking for the drivers.
Officials said the crash is under investigation and that charges are pending.
Copyright 2013 by WESH.com All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Talitha Vickers
News Reporter
WESH 2 News reporter Talitha Vickers joined WESH 2 News in 2011.
The native New Yorker began her career as a field producer with New York's WWOR-TV. She then moved from behind the camera to in front of the camera as a "one man band" at News 12 The Bronx, a cable news channel. As a "one man band," she shot her stories, wrote them, and edited them for air. From there, she reported at WBOC-TV in Salisbury, Maryland, and WCCB-TV in Charlotte, North Carolina before anchoring and reporting at a competing TV station in Orlando and finally, coming to WESH 2 News.
Talitha graduated from Monmouth University in New Jersey.
When she is not reporting, you can find Talitha participating in school projects, mentoring programs, community service and philanthropic work. Talitha spends time volunteering with local Boys and Girls Clubs and at Stand Up for Autism events. She also hosts The Academic, Cultural, Technological and Scientific Olympics (ACT-SO) and Hope Now's Annual Back to School Event and Health Fair. Talitha is also a member of the Central Florida Association of Black Journalists. When she has a moment to spare you'll find Talitha running (she was a competitive track and field player in college), reading, playing tennis, canoeing, fishing, shopping and perhaps nursing a Nintendo Wii Sports injury.


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Amanda Seyfried could learn a thing or two about acting from her dog, Finn.
We don't think he'll get a nod at the A-Cat-emy Awards this year – but there's plenty of buzz around our office about the Australian shepherd's emergence as a serious and method-inspired actor, who's not afraid to take risks on the screen with a little James Franco-worthy performance art.
Donning a masquerade mask in an Instagram video Seyfried posted Monday (watch below), Finn comes off as deliberately camera shy (so in character!), standing completely still as the camera captures him from different angles. Like the Lovelace star, the dog acts with his eyes – which appear to be saying, 'Really?'
But this is not the first time Finn's onscreen charisma has been recognized. Seyfried told Ellen DeGeneres in May her pooch is prime to make his big screen debut.
"I got him cast in his first movie," she revealed. "I can't really talk about his character, but it's going to shoot in September. I'm really excited about it. He's really excited about it."
The Daily Treat: Amanda Seyfried Is Doing Dog Performance Art Now


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Core, Fund, Jersey Youth Academy to Benefit from Heifers Selling at All American Jersey Sale
Core, Fund, Jersey Youth Academy to Benefit from Heifers Selling at All American Jersey Sale
Two Registered Jersey™ heifers, one donated by Brentwood Farms, Orland, Calif., and the other by the TJF/Lee Syndicate of Boonville, Miss., will sell for the benefit of national Jersey youth programs at The 59th All American Jersey Sale on November 6, 2011 in Louisville, Ky.
BW Region Louisa W418, sired by Maackdairy Region-ET (GJPI 91), has been donated by AJCA President Robert Bignami in memory of Norma "Duffy" Lyon, the Jersey woman from Toledo, Iowa who achieved international fame as "The Butter Cow Lady." She studied animal science at Iowa State University, where she met her husband of 61 years, G. Joe Lyon, a past-President of both the American Jersey Cattle Club and National All-Jersey Inc. Together they raised nine children. "Duffy" was honored with Honorary Membership in the American Jersey Cattle Association at its 2007 Annual Meeting.
The heifer is out of BW Louie Louisa ET681-ET, projected to 24,320-958-786 m.e. on her first lactation and ranked seventh in the nation for genomic Jersey Performance Index™ (October, 2011). The heifer's grandam is BW Avery Katie ET121-ET, Excellent-93% with four lactations over 30,000 lbs. milk. She has 18 sons in A.I. service, among them the bull syndicated in 2008 to provide seed money for the highly successful Jersey Youth Academy, BW Academy-ET (GJPI 168).
Proceeds from this heifer are designated for the Maurice E. Core Jersey Youth Fund, created in 1993 to commemorate his 37 years of service to the Jersey breed. It provides financial support for youth activities, primarily at The All American Junior Show.
The second heifer, TJF/Lee Valentino Mamme 980-ET, is a Vision Gift to Jersey Youth Academy by her owners, Bradley and Carla Taylor and Lynn Lee. She is ranked on the AJCA Top 500 Heifer List for genomic JPI (215) and carries an A.I. contract. Sired by All Lynns Louie Valentino-ET (GJPI 261), her dam is Vantage Lemvig Mamme, Excellent, with four lactations averaging 22,920-1,101-838 m.e. and the dam of 13 sons in A.I. service.
The mission of the Jersey Youth Academy is to attract, educate and retain talented young people for careers in the Jersey dairy business. All costs for participants selected from a national pool of applicants are paid by the Academy's 501(c)(3) educational foundation created in June of 2008. Contributors to the foundation represent a broad spectrum of Jersey breeder and dairy industry support, with the largest contribution to date coming from the all-donation National Heifer Sale on June 25, 2011.
Pedigrees for both heifers are contained in the catalog for The All American Jersey Sale, posted on the USJersey.com website.
The American Jersey Cattle Association, organized in 1868, maintains identification and performance records for dairy herd owners and provides services that support genetic improvement and greater profitability through increasing the value of and demand for Registered Jersey™ cattle and genetics, and Jersey milk and milk products. The association has made strategic investments in Jersey youth since 1958 when it created the National Heifer Sale to provide annual funding for educational programs, recognition awards and scholarships. For more information, visit www.USJersey.com.


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Publications /
AIB: Agricultural Information Bulletin /
The 2002 Farm Act: Provisions and Implications for Commodity Markets
Stay Connected
Agriculture Information Bulletin No. (AIB-778) 67 pp, November 2002
The Farm Security and Rural Investment Act of 2002 (2002 Farm Act), which governs agricultural programs through 2007, was signed into law in May 2002. This report presents an initial evaluation of the new legislation's effects on agricultural commodity markets, based on sectorwide model simulations under alternative policy assumptions. The analysis shows that loan rate changes under the marketing assistance loan program of the 2002 Farm Act initially result in an increase in total planted acreage of eight major program crops. This increase in plantings, however, is relatively small (less than 1 percent), partly due to the inelasticity of acreage response in the sector. In the longer run, the simulations indicate that overall plantings of the eight program crops studied are lower under the 2002 Farm Act than under a continuation of the 1996 Farm Act. This result mostly reflects larger enrollment in the Conservation Reserve Program and increased plantings of dry peas and lentils, although planted acreage for the eight program crops is reduced by less than 0.6 percent. The effects of the 2002 Farm Act on the livestock sector and retail food prices are relatively small. Farm income is increased, mostly due to higher government payments to the sector under the new law.
Keywords: Farm legislation, 2002 Farm Act, agricultural programs, commodity programs, marketing loans, counter-cyclical payments, direct payments, planting flexibility, base acres, payment yields, farm income, risk management, FAPSIM
In this publication...
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Last updated: Wednesday, April 27, 2016
For more information contact: Paul Westcott, Edwin Young, and Michael Price


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Quote from: emag on July 05, 2013, 04:35:25 PMWhat caught my eye was "offer ends SEP 30 '13" ....... gives a bit of breathing room, if it really lasts that long.The mail-in rebate is good until Sept. The kit price (at least for the 6d) is only good until Jul6th so you got only hours, really
What caught my eye was "offer ends SEP 30 '13" ....... gives a bit of breathing room, if it really lasts that long.
This is looking like a very nice deal... although I'm reading the fine print on the rebate form and saw this:"Offer does not apply to purchases of refurbished or used products nor for eligible products packaged together and sold for one price."Unless I'm reading it wrong, it seems like it wont apply to either the 6D or 5DMKIII deals since they are all packaged together and sold as one price.
It's actually $2399 once you check out.
These deals should be clarified, because some people cannot see the price reduction right away (until they go to the cart checkout). Yeah, I know. Some people can't read. LOL
I know that you get a -$200 discount at the end of the checkout process, but where exactly does it come from? I don't see it listed anywhere on the product pages.Also, does anybody know how easy it is to resell the printer on ebay?
Deal like this make me sad and make Canon Australia look like an absolute joke.
Wow, this looks to be a very interesting deal...w/the 5D Mark III. This is a camera I'd interested in getting to use as my primary and my current 5D Mark II as the secondary. As I've never purchased camera gears w/rebates, does anyone know what kind/type of rebate is this in the form of (Amex gift card?). Also, anyone currently using the Pro-100? What are your thoughts on this printer? Also do you use the printer for other jobs aside from photos?
Mail-in rebates?! WTF?!Instant rebates or nothing.
It makes me sad to see an offer like this. In Europe we pay at least $ 2.100 for the 6D body ONLY, and we never get offers like this. Sadly the offer is only valid for the US only, this kit would still be much cheaper including shipping, handling and duties than what their charge us here.


text: "Philosophy's the 'love of wisdom', can be approached in two ways: by doing it, or by studying how it has been done," so writes the eminent philosopher Roger Scruton. In this user-friendly book, he chooses to introduce philosophy by doing it. Taking the discipline beyond theory and "intellectualism," he presents it in an empirical, accessible, and practical light. The result is not a history of the field but a vivid, energetic, and personal account to guide the reader making his or her own venture into philosophy. Addressing a range of subjects from freedom, God, reality, and morality, to sex, music, and history, Scruton argues philosophy's relevance not just to intellectual questions, but to contemporary life.


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Philippi mayor questions manager's role
December 23, 2013
PHILIPPI — Philippi Mayor Jerry Mouser's questioning whether City Manager Karen Weaver should be permitted to serve on the Philippi Building Commission has sparked a debate among city officials....
Just another example of Mousers negativity at the city. Nobody can work with this man. He's against everything.
1 Agrees | 4 Disagrees | Report Abuse »
Majority of folks in America are 'against' lazy politicans on left that won't WORK! It's called 'common sense' which is lacking in the leftist party of liars and deceivers.
2 Agrees | 2 Disagrees | Report Abuse »
Maybe if the City wasn't so corrupt the Mayor wouldn't have to be so negative. Ask about the City Manager and her cover up of the sewage flow meter problems....? Raw sewage going in the river at a rate higher than what is being recorded. How about the insurance policy she failed to pay for at the Industrial Park -- and now a fire with damage that will cost the City significant money to repair.
4 Agrees | 1 Disagrees | Report Abuse »
Ms. Toothman should ask the City Manager about that insurance policy she didn't pay... and the fire over at the Industrial Park. Most of those in power in Philippi are only interested in keeping their "jobs for life" -- what else would they do -- work at the Dollar General?
0 Agrees | 2 Disagrees | Report Abuse »
What kind of corruption will Councilman Larry and his preacher man friend look to cover up this week?
0 Agrees | 1 Disagrees | Report Abuse »
Since "Mayor" is just a title then basically what you're saying is the sole responsibility of everything good or bad that happens in the city of Philippi rests upon the shoulders of Ms. Weaver? Is the city so broke they can't afford to purchase insurance for the Industrial Park? Where does the Main Street Program get their funding for the city's "beautification" program? Allegedly there have been thousands spent on floral baskets,etc. in the past to beautify a no longer thriving downtown. If it is city funded your priorities need a bit of work.
1 Agrees | 0 Disagrees | Report Abuse »
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text:
- Publisher National Galleries of Scotland, National Library of Scotland, and NMS Enterprises Limited - Publishing, National Museums Scotland
- Size 16.5 x 24 cm
A Burns Miscellany
Recognised internationally as a poet of wide range and tone, Burns's poems, songs, and letters - his enormous legacy to Scotland - came from the heart, but were crafted with a sure-footed and keen intelligence. Their power, poignancy, humour and beauty endure in our own day. As a result of his encounters with its landscape, folklore and people, Burns unconsciously helped to fashion what became the modern image of Scotland.
To mark Homecoming Scotland 2009, the National Library of Scotland, National Museums Scotland, and the National Galleries of Scotland have collaborated to highlight some of the treasures in their care. Shown here are select and iconic examples from the national collections including paintings, objects, books and manuscripts relating to Robert Burns's life, work and heritage.
16pp | Paperback | 18 illustrations


text:
Greywater reuse systems vary tremendously in size and scope and hence describing specific repairs is difficult. Typical repairs may include: cleaning and replacing filters, maintaining plumbing and pipe connections, pump maintenance, repairs to the greywater irrigation system, and patching leaks.
If you have any questions about how to repair or maintain your greywater system, contact the dealer, the installer, or a professional plumber. Be aware that many plumbers may be unfamiliar with greywater systems.


text:
New Versions Of All Emulators And Source Release
Posted 13 November 2007 - 11:09 PM
(rewind, slowdown, rumble, better cheat code options, etc, etc)
Note that some of these do not have rewind support enabled for a variety of
reasons. Check the README.TXT files for information specific to each port.
I know that I said that I was going to try and resolve bugs and update cores
to more recent versions, but I don't have nearly as much free time as when
I first started doing ports. I made it through most of them, but the last
dozen or so were taking too long to finish and I really wanted to get these
out the door.
...and Snes9XBox
I know, I know...but it's not really a finished product. It's something that I threw
together about 3 years ago and have been updating with my current user interface along
the way. Purists will still want to use ZSnexBox. Compatibility is better in ZSnesBox
as well because it's based off of ZSNES and this is based off of Snes9X v1.43. There
is no lightgun support, no mouse support, and rewind support is flaky. All the other
features like save states, cheat code searching, etc, etc are working.
The sources to everything are now up on xbins under emulators/xport_src_new along with
a readme file for (brief) instructions on how to compile. I can't give instructions
on how to make XBox programs in general (that's left as an exercise for the reader)
but I can assure you that I've tested these packages to make sure they compile correctly
under MSVC with the XDK installed. It's all the source - every last bit.
My involvement in the XBox era is winding down. I guess it already has been winding down
for a while. There will probably be a handful of updates in the future and perhaps a new
project or two, but it's possible that this is it for me. I hope others will pick up these
projects and improve them. There's still a lot that can be tweaked/improved.
There's a very good chance that incorporating the new DOSBox core will result in a usable Dynamic
CPU which would give it a very nice speed boost.
Mednafen core might be worth updating, but note that as of v0.8 PCE CD emulation is supposed
to be much more taxing on the CPU. However, it might be worth it to strip out the Wonderswan
core into a separate project since that's supposed to be a better/tweaked version of oswan
(which is the core of WonderswanX). It might make more sense to find the changes in the oswan
portion of Mednafenx and implement them into WonderswanX though. There is also a PCFX core
(probably too taxing for the XBox) and a NGPC core (but the ngpc core is based on neopop
and I don't think much has changed in it - don't know if the emulation is improved at all.)
Atari7800 source is basically a stripped down MESS but all the MESS source files are included
in the package. One should be able to copy the atari7800x source package into another dir
and adjust the project settings to exclude A7800 files and include another machine's files
to make a new port of something else in MESS.
NeoGenesis could be patched to allow for >32MBit games - but this is surprisingly more
work than one might expect because of the memory constraints of the XBox. It
could be done more easily using virtual memory, but then general emulation performance
would suffer. It's doable without VM, but requires more time than I feel like giving -
especially because it's only useful for one or two games.
Many other projects could use core updates like BlissX, BlueMSXBox, etc to improve
Then of course there could be all sorts of new projects using my core as a base.
Potential projects include BBC, Bally Astrocade, Vectrex, Coco, Arcadia, and Sam Coupe
which all have decent open source emulators available for them. They've been on my todo
list for quite a while, but I just haven't found the time for them.
Oh...as an aside, if anyone knows of anyone who still does xbox tweaks who can construct a
completely silent (or nearly totally silent) XBox, please send me (XPort) a PM on
forums.xbox-scene.com. There's a lot of antiquated information on the 'net on this
subject and I just don't have the time to go the trial-and-error route.
And as always....enjoy!
Posted 13 November 2007 - 11:18 PM
All I want is to say "Thank you" for all your great Xbox releases!
Seems to be the end of an era...
Posted 14 November 2007 - 12:32 AM
All the best for the future....
Posted 14 November 2007 - 01:25 AM
Your contributions are pretty much the main base of the XBox homebrew 'scene'.
Whenever someone was considering getting an XBox and wanted to know what it was capable of homebrew-wise, it seems that the very first or second thing -always- mentioned was your emulator ports, along with the XBMP/XBMC project.
Again, thanks for all your work in the past and possible future...your projects probably have space used on most of the homebrew-capable XBoxes out there.
Posted 14 November 2007 - 01:34 AM
Edited by DZIAD, 14 November 2007 - 01:35 AM.
Posted 14 November 2007 - 01:35 AM
I originally got into modding, because i saw someone running one of your emus on an xbox a couple of years back, and have been messing with my xbox ever since, LOL.
Here's to you and all your hard work.
Posted 14 November 2007 - 02:15 AM
Posted 14 November 2007 - 02:24 AM
Edited by RoboChicken, 14 November 2007 - 02:25 AM.
Posted 14 November 2007 - 05:16 AM
Posted 14 November 2007 - 05:17 AM
Posted 14 November 2007 - 05:22 AM
Posted 14 November 2007 - 05:51 AM
nice work.
Posted 14 November 2007 - 06:01 AM
Thank you!
Posted 14 November 2007 - 06:03 AM
Posted 14 November 2007 - 07:04 AM
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text:
We work with brands and move businesses forward through strategy, design and digital solutions.
Find a selection of our work below. For inquiries, please get in touch.
We enjoy creating our own products and brands, from natural hand-picked herbal tea, to clothing stores and iPhone/iPad applications. It keeps us on our toes and gives us an edge we then apply to our client work, constantly overlapping industries and drawing inspiration from one to another. There's a nice synergy doing work for our clients and being one ourselves.


text:
Eric Jackson keeps it real.
How to help
For more information about R3 Inc. or to volunteer, visit www.r3inc.org or call Karen Williams at 577-4860.
He wants young African-American males to make education cool again.
"You can still have a sway in your step and be educated." That message, somehow, got lost on too many young black males, he said. "Education is important. And reading is fundamental."
Through his year-old nonprofit, R3 Inc. (Real Talk, Real Action, Real Results), Jackson challenges more than 40 teen boys and girls to stay off the streets and get an education.
Every day after school at the Shaw Community Center at Mary and America streets, the 35-year-old Burke grad is spreading this message to young people on the East Side.
Word is spreading: the center is a place for real talk; to read and do homework; and shoot hoops or throw some punches — at a boxing bag that is.
More role models
Jackson started the nonprofit because he saw a need for more positive role models, especially black males. He focuses on the social aspect — building self-esteem, self-worth because teens need emotional development.
He tells them to look in the mirror and not rely on others to make them successful.
Jackson, a Navy vet and the father of a 7-year-old and a 13-year-old, tells teens the best way to enrich their lives is through education. "It's the No. 1 priority."
He brings in various speakers. Real Talk roundtable discussions allow teens to talk about any problem.
Additionally, Jackson's wife, Kimberly, CEO of the group, holds Girl Talk.
Eric Jackson wants the black community to come together and do more to help young people.
Not everyone on the street corner is a drug dealer. Seven out of 10 people are just "hanging out."
He tells teens there are too many negatives to being a drug dealer. "You either go to jail, or you get killed."
But instead of shunning misguided teens, Jackson, his wife and David White, group chief operating officer, try to show them a better way.
They offer teens a chance to come in off the corner and do constructive things like reading for 20 minutes a day or boxing.
Now an equipment tech in the operating room at Roper Hospital, Jackson, who is studying Human Services at Southern Wesleyan University, was not always big on education.
He grew up with a single parent and "I experimented with the streets, but I had a praying mother."
Also, back then, the community kept up with what teens were doing.
He thinks more people should get involved with teens by volunteering.
Get involved
The center, the former Boys & Girls Club, has a library with 250 donated books; Jackson wants even more so teens can read at home.
It was a struggle at first, but now many look forward to reading about sports, music, different places and African-American history.
Jackson sees his R3 Inc. as a path builder, providing a way for teens and adults to get jobs by learning how to fill out applications, get GEDs. He is big on parent participation.
One day he hopes to expand into the schools.
Jackson is a big man with a big heart who has big dreams for young people. The only thing bigger is his enthusiasm for what he does.
He can use your help. For more information or to volunteer, visit r3inc.org or call the center's manager, Karen Williams, at 577-4860.
Reach Assistant Features Editor Shirley A. Greene at 937-5555.


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Global tobacco survey: Key findings
POSTED: 09:26 AM PDT Mar 15, 2012 UPDATED: 09:27 AM PDT Aug 17, 2012
A new global tobacco study found that about half the men in numerous developing nations use tobacco, and women in those regions are taking up smoking at an earlier age than they used to. Here's a look at key findings from the survey as well as graphic warning labels the Food and Drug Administration has placed on cigarette packages in an effort to deter smoking in the U.S. [Warning Graphic]
The views expressed are not those of this company or its affiliated companies. Please note by clicking on "Post" you acknowledge that you have read the Terms Of Service and the comment you are posting is in compliance with such terms.blog comments powered by Disqus