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Endocyte Reports 2010 Financial Results
WEST LAFAYETTE, Ind., March 10, 2011 (GLOBE NEWSWIRE) -- Endocyte, Inc. (Nasdaq:ECYT), a biopharmaceutical company developing targeted therapies for the treatment of cancer and inflammatory diseases, today reported consolidated 2010 financial results and reviewed 2010 development highlights.
"Endocyte made significant progress in demonstrating the promise of our small molecule drug conjugate (SMDC) platform during 2010," said Ron Ellis, President and CEO. "We have generated positive results in our PRECEDENT clinical trial, a randomized phase 2 trial of our lead drug, EC145, and companion imaging diagnostic, EC20, in patients with advanced ovarian cancer. We look forward to sharing the PRECEDENT results in more detail at an upcoming medical conference. We also recently completed an initial public offering, which will provide the funding to move this program forward and execute the similarly designed phase 3 PROCEED clinical trial."
Fourth Quarter and Full Year 2010 Results
- Endocyte reported a net loss for the fourth quarter of $3.4 million, or $3.57 per basic and diluted share compared to a net loss of $5.6 million, or $6.16 per basic and diluted share for the same period in 2009. The lower net loss for the fourth quarter of 2010 was due to a reduction in research and development expenses related to the decrease in patients remaining on the phase 2 PRECEDENT trial and to the recognition of $1.5 million in grant income from the Qualifying Therapeutic Discovery Project program.
- For the full year 2010, Endocyte reported a net loss of $20.1 million, or $21.77 per basic and diluted share compared to a net loss of $17.0 million, or $18.67 per basic and diluted share in 2009. Revenues of $3.0 million were recorded in 2009 related to a milestone payment from Bristol-Myers Squibb associated with a license agreement that has since terminated. No revenues were recorded in 2010.
- Research and development spending was $14.6 million in 2010 compared to $14.8 million in 2009. The decline was driven by a reduction in payroll expenses allocated to research and development in 2010 resulting from a shift in management time to administrative activities, partially offset by increased costs associated with preparations for the phase 3 trial of EC145 and EC20.
- General and administrative expenses were $6.0 million in 2010 compared to $3.9 million in 2009. The increase was primarily the result of increased expenses associated with the growing patent portfolio and professional fees associated with various business development and financing activities.
- At December 31, 2010, Endocyte had $16.9 million in cash, cash equivalents and short-term investments. This balance does not include $3.7 million in net proceeds from the second closing of the subordinated promissory note offering or the $78.8 million in net proceeds from the initial public offering, both of which occurred in the first quarter of 2011.
- Endocyte established a $15.0 million credit facility with Mid-Cap Financial and Silicon Valley Bank in August 2010, replacing a previous credit facility. By December 31, 2010, Endocyte had drawn the full $15.0 million in principal against that facility. Principal payments on the credit facility will begin in April 2011 and extend for a 30-month period.
- Endocyte received a total of $11.8 million in net proceeds from a subordinated promissory note offering (split between two closings of $8.1 million in December 2010, and $3.7 million in January 2011), which automatically converted into 2,335,823 shares of common stock upon the closing of the initial public offering.
- In February 2011, Endocyte completed its initial public offering, selling 14,375,000 shares of common stock (including 1,875,000 shares of common stock related to the exercise of the over-allotment option by the underwriters) and raising net proceeds of $78.8 million.
- Total common shares of 29,661,614 were outstanding after the initial public offering. This was comprised of shares issued in the initial public offering and conversion of the promissory notes summarized above in addition to 1,203,228 shares of common stock and 11,747,563 shares of convertible preferred stock outstanding prior to the offering.
- Achieved primary endpoint in PRECEDENT clinical trial (randomized, multi-center, international phase 2 clinical trial of EC145 and EC20 in patients with platinum resistant ovarian cancer): The combination of EC145 and standard chemotherapy (pegylated liposomal doxorubicin) showed an improvement in the time to disease progression or death compared to standard chemotherapy alone. This improvement was more substantial in patients who were selected with the companion imaging diagnostic, EC20. Complete results will be presented at an upcoming medical conference.
- Completed single-arm multi-center phase 2 clinical trial of EC145 in patients with advanced non-small cell lung cancer: Patients were scanned with EC20 to assess their receptor status and then received EC145 as a single agent therapy. EC145 achieved promising progression free survival and overall survival results in this trial, particularly when analyzed according to the EC20 assessment of the presence of the targeted receptor. Patients whose cancer over-expressed the receptor targeted by EC145 in all of their tumors (n=14) achieved a median eight-week disease control rate of 57 percent, compared to historical disease control rates of 21 to 30 percent reported in other studies. Patients in this same population achieved median overall survival of 47.2 weeks compared to 14.9 weeks in patients who had at least one, but not all tumors which over-expressed the targeted receptor (n=14).
- Selected new companion imaging diagnostic candidate: EC0652 is a companion imaging diagnostic targeting the prostate specific membrane antigen (PSMA) found on most prostate cancer cells. This imaging agent will be evaluated in an early phase clinical trial during 2011.
- Selected new inflammatory disease drug candidate: EC0746 is a new SMDC targeting cells involved in inflammatory disease. In preclinical models, EC0746 was shown to be safe and reduced inflammation more than the most commonly prescribed anti-inflammatory agent, methotrexate.
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Disappearing Picks
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Re: Disappearing Picks
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Yes, Wallace- he's soft. Exactly what I said. He basically was opposite side of Aaron Williams much like being the opposite side of Ike Taylor. He was picked on consistently, I bet on OK STATE and was highly rewarded.
I'll completely 100% give you that the Steelers can draft well in all the other positions but there CB scouts blow. I posted many times that Heyward and Gilbert will be good (although I'm suspect of the 11th DE... THE 11 DE being the uncovered GEM that 29 other teams missed but the DE's / LB's we draft are good)
Name one CB that Tomlin has drafted that has contributed?
Name one CB that Tomlin has drafted that has made any significant play?
Maybe, Carnel Lake will pull a Kugs and get any of the CB's moving forward but I'm pretty doubtful given the last 3 years of reverse in terms of developing CB's
I said a joke a while ago, it seems that other teams develop CB's quickly and our have to go through some kind of JEDI KNIGHT apprenticeship.
To summarize, I don't think we'd did enough to stop an Elite passing team. I'm not worried about the Brownies or Ravens.
To finesward, yeah, I'm a toolbag because I present facts about players and I don't like our Pass Defense. BTW, I drive a 2008 BMW M3 Coupe so go **** off little man.
I'll agree with you that the secondary, much like the O-line before Pouncey, has been ignored for far too long. But that's not an excuse to reach for a CB the quality of which they can get with a later pick.
Here's Carnell Lake's opinion on the Brown pick:
Surprisingly, new Steelers secondary coach Carnell Lake said Brown was the more polished of the three Texas cornerback prospects in this draft.
"Probably the best cover corner coming out" of Texas, Lake said.
"Aaron Williams was the first [Texas] corner taken. Aaron's bigger, but we thought he was more of a safety.
Read more:
We don't need a big playmaker at corner. We already have a lot of impact guys on the defense. We need a corner who can cover. And they obviously thought Brown was just as good as the guys they could have selected with their first-round pick.

subset: commoncrawl


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Okay. I will wait just a little bit. I'm want to watch two teams one more time. I do have my team name though. I'll think I'll my team ALIVE & Jivin'.
I thought I had posted my preliminary team yesterday, but I don't see it so maybe I put it in the wrong place. But, subject to change by the deadline, here's my team.
Team Name: Twist and Shout
Superstar Couple: Zendaya and Val
Team 1: Ingo and Kym
Team 2: Dorothy and Tristan
Team 3: Kellie and Derek
Reserve Couple: Jacoby and Karina
Those who would give up essential liberty to purchase a little temporary safety deserve neither liberty nor safety.
-- Benjamin Franklin, Historical Review of Pennsylvania, 1759
Well here goes nothing.
Team Name ... Tone Deaf with Two Left Feet
Superstar Couple ... Kellie and Derek
Couple #1 ... Zendaya and Val
Couple #2 ... Dorothy and Tristian
Couple #4 ... Ingo and Kim
Reserve Couple ... Jacoby and Karina
You could be the juiciest, most ripe peach, but there is still going to be someone who doesn't like peaches.
I'm going to make some pool team avatars as I get around to it. I love playing around with graphics and need something to do when I'm bored at work (which is most of the time). Here's one for karalott!
JLuvs is up next!
Haha, that's awesome pika!
You definitely rock for doing all of this!
Keep your feet on the ground, when your heads in the clouds!


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Hey everyone, New to this great site! My Father-in-law has a Ruger M77 with the low-glare stainless finish. We are puting a muzzlebreak on it and would, obviously, like it to match. Having trouble finding a way to match this rare color. Any suggestions? Thanks!
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Bead blasting the brake will probably come pretty close to matching. The best way to get it to match perfectly would be to re-bead blast the whole gun with the brake. David
David Clevingerwww.dcengraving.com
Brownells sells oven cure finishes and one of the colors is "stainless steel gray". The description says it's supposed to be a very good match for bead blasted matte stainless guns, hence the name. Might be worth a look, and it's only about $15 a can.http://www.brownells.com/aspx/NS/store/ProductDetail.aspx?p=1143&title=AEROSOL%20BAKING%2 0LACQUER Dura Coat might be another option if you aren't opposed to a coating type finish. Through experience I can tell you the Duracoat is more durable, but a little more involved to apply. Not difficult though. If you call Lauer directly you might get a decent color match right off the bat. They offer MANY colors.http://www.lauerweaponry.com/
"People live too long, dogs don't live long enough" - FTF Member-


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Grand Theft Auto V delayed until SeptemberRockstar has just revealed that Grand Theft Auto V now has a solid launch date: September 17, 2013. The development team notes that a little more time is needed to polish the game, and the original "spring" deadline has been pushed back to September. I for one am totally fine with this: take all the time you need to ship a complete game, Rockstar! So, it looks like the wait is on. Now we just need more information on the possible PC version of the game, and maybe a Wii U port down the line? Grand Theft Auto V Is Coming 9.17.2013 [Rockstar] Hey remember that GTA V 'story DLC' that was promised? I guess it still exists 12:30 PM on 12.18.2014 Grand Theft Auto V Updates, Screenshots, & VideosComments not appearing? Anti-virus apps like Avast or some browser extensions can cause this. Easy fix: Add [*].disqus.com to your software's white list. Tada! Happy comments time again.
Did you know? You can now get daily or weekly email notifications when humans reply to your comments.


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American Apparel T-shirts are made with 100% fine jersey cotton combed for softness and comfort. (Athletic Grey and Athletic Blue contain 50% polyester / 25% cotton / 25% rayon)
The strangeness of this is really pulling me in. I feel like its on the verge of transforming into something and if I blink I'll miss it! Love this piece.
Hi ArtsyDesigny, in this case as with most of my work, it's traditional drawing. Digitally the only thing I do is, usually, colour the background!
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Chelsea Football Club
- Nickname:Blues
- Founded:1905
- Manager:Jose Mourinho
- Ground:Stamford Bridge
- Capacity:42440
- Last Game: 21-Feb-2015 15:00
- Chelsea1
Burnley1 - Full match report
Lens support Kakuta sanctions
04 Sep 2009 - 07:53:07
Racing Club Lens have backed FIFA's decision to punish Chelsea for luring teenager Gael Kakuta away from the French club.
The Blues face not being allowed to sign any new players until January 2011 for their previous conduct, having taken Kakuta to Stamford Bridge in the summer of 2007.
Chelsea and the player have also been fined 780,000 euros, while also being forced to pay Lens training compensation of 130,000 euros.
Lens chairman, Gervais Martel, told AFP: "We expected this kind of decision. The player was under contract with us and they came and stole him away from us.
"Chelsea didn't follow the rules. They contacted the player when he wasn't even 16 yet and while he had been contracted to our training group from the age of eight.
"The financial sanction isn't over the top given the nature of the infringement, but it's really quite significant when it comes to not being able to recruit players.
"It's an important message given that protecting up and coming youth players who are contracted to clubs is an issue being followed closely by (UEFA president) Michel Platini."
Related Chelsea News
Related Chelsea News


text: For complete online access to The Roots of Roe v. Wade The Leading Edge Healing the Pain Choosing Love & Making Life Nice Killers Every issue of Touchstone also contains short commentaries by our editors, notices of books you should know about, and our spirited letters section. Order issues of Touchstone at our online store. Subscribers can read issues in digital format at the NEW Touchstone digital archives! Subscribe to Touchstone today! |


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Lady Adiva of Harad recalls the longest day of her life while
relaxing with Arwen and Éowyn. Dedicated to Ellynn and all my friends who
desired to see the ladies relaxing together.
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Nightmare Alley (eBook)DescriptionNightmare Alley begins with an extraordinary description of a freak-show geek—alcoholic and abject and the object of the voyeuristic crowd's gleeful disgust and derision—going about his work at a county fair. Young Stan Carlisle is working as a carny, and he wonders how a man could fall so low. There's no way in hell, he vows, that anything like that will ever happen to him. And since Stan is clever and ambitious and not without a useful streak of ruthlessness, soon enough he's going places. Onstage he plays the mentalist with a cute bimbo (before long his harried wife), then he graduates to full-blown spiritualist, catering to the needs of the rich and gullible in their well-upholstered homes. It looks like the world is Stan's for the taking. At least for now. About the AuthorWilliam Lindsay Gresham was born in Baltimore on August 20, 1909. His family moved briefly to Fall River, Massachusetts, in 1916, then to New York City, where he graduated from Erasmus Hall High School in Brooklyn in 1926. Gresham's was a tortured mind and a tormented life, and he sought to banish his demons through a maze of dead-end ways, from Marxism to psychoanalysis to Christianity to Alcoholics Anonymous to Rinzai Zen Buddhism. From these demons came his novel Nightmare Alley (1946), one of the underground classics of American literature. He wrote one more novel, Limbo Tower (1949), which went largely unnoticed. Three nonfiction books followed: Monster Midway (1953), Houdini (1959), and The Book of Strength (1961). Nightmare Alley brought Gresham fame and fortune, but he lost it all. The second of his three wives, the poet Joy Davidman, left him in 1953 for the British author C. S. Lewis. He killed himself in New York City on September 14, 1962. Praise for Nightmare Alley… "[Gresham's] legacy was a brilliant and horrific book - read it and you'll never refer to someone as a geek again." --The Times (London) "Written in 1946 and just reissued, Nightmare Alley was adapted into one of the most scabrous films of the 1940s. It's a grifter story, a carny story, whose main character is Stan Carlisle, a handsome con artist/fake mind reader who slowly works his way down the food chain until there's nothing left for him except the job of circus geek. It's a novel in which no ray of light ever penetrates. The novel is a fascinating curio of undoubtedly justified self-loathing -- Gresham's second wife, the poet Joy Davidman, left him for C.S. Lewis. Gresham committed suicide in 1962. The new edition has a preface by Nick Tosches, who is working on a biography of Gresham. Certainly one of the most valuable reissues of the year." --The Palm Beach Post "For contemporary audiences who have never strolled through sawdust and tinsel, the carnival chapters of Nightmare Alley offer an unnerving slice of seedy Americana." —The Baltimore Sun "The 'nightmare' of the title rings true, for this delirious and unstoppable novel…inverts the American dream. The plot turns the Horatio Alger myth on its head and the psychology leans on Freud, but the torment, the pervading sense that the human creature lives in a trap he or she is doomed never to escape, comes from the heart and mind of the author. Never was noir more autobiographical than here….Nightmare Alley remains a masterpiece, not only due to its driving narrative power, but because it's underpinned by the premise that the human animal is alone, helpless in the face of destiny, stumbling in the dark, down the nightmare alley toward the inevitable wall of death at the end. Yet we can't stop ourselves hoping, and fearing, that there might be something beyond that wall. The message of this disquieting book couldn't be more human, yet that message is metaphysical rather than moral." —Los Angeles Times "For fans of vaudeville and magic, the book is a treasure trove of trade secrets." —Walter Kirn, The New York Times "Nightmare Alley is a portrait of greed seen through the rise and fall of a carny con man." —Publishers Weekly "Gresham…wrote with vivid punch and a close understanding of the carnival world." —Los Angeles Times A "remarkable study in the disintegration of carnival show heel." —The New York Times "An impressive low-life novel." —The Observer (London) "Mr. Gresham yanked the reviewer into the midst of his macabre and compelling novel, and kept him a breathless captive until the tour was over. It's a truly rewarding whirl through his nightmare alley…All of it adds up to Grade-A guignol with a touch of black magic about it…If you enjoy hundred-proof evil-and a cogent analysis of same with your nightcap-then, in the words of the Ten-in-One barker, hurry, hurry, hurry!" —James MacBride, The New York Times "While Gresham is usually described as a 'popular novelist,' the epithet fails to capture his contemporary notoriety. Gresham wrote the 1946 best-seller Nightmare Alley (dedicated to Davidman), a grotesque noir classic about the carnival demimonde, later made into an arresting film with Tyrone Power and Joan Blondell. One reviewer described the book as a 'tough, relentless, colorful novel that exposes the private world of the freaks in order to comment on a sick, degrading society.'" —San Francisco Chronicle "Certainly one of the most valuable reissues of the year." —Canada.com" ...capable of eating toasted little Cormac McCarthy novels for breakfast." —Chicago Reader "William Lindsay Gresham was obsessed by the darker side of circuses and carnivals. His knowledge was profound, his sensitivity to the vice and viciousness lying just underneath the tinseled, gaudy, surface, remarkable." —John Howard Reid, Hollywood Gold "Gresham…has something of Nelson Algren's mordant power in picturing denizens of the lower depths…his is a promising contender for heavyweight honors in the rough, tough and morbid division." —Jack Conroy, The Chicago Defender |


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Yesterday markets plummted.
Today they're booming.
The big difference seems to be: A total rethink of what Mario Draghi said yesterday at his press conference.
CNBC's Steve Liesman has this awesome nugget.
(via @dukestjournal)
Please follow Clusterstock on Twitter and Facebook. Join the conversation about this story »
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Via Mark Grant, author of Out of the Box, The Rhapsody of the Markets Recently I was on CNBC and Steve Liesman, who I know personally and is a very thoughtful fellow, made the comment that I had called the events right but I had not... Read Post
CNBC's Rick Santelli, who reports from the CBOT floor, went totally nuts on this morning's "Squawk Box" during an exchange with senior economics reporter Steve Liesman right after initial jobless claims came out. "Rick, I really wan... Read Post
CNBC's Steve Liesman is a huge fan of Grateful Dead. When he's not interviewing a Fed president or attending a Ben Bernanke presser, the senior economics reporter is probably jamming with his band. Liesman, a self-proclaimed "Deadhe... Read Post


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You may be right. I wouldn't feel 100% confident betting against that, but I would definitely feel > 50% confident. You seem to be going to an extreme to emphasize the point that he isn't as good as others claim. I've seen the opposite tactic when certain people state that a player will end up in the HOF. But imagine if you had to put real money on a prediction like that. Odds are that no matter how badly he plays this year, he will get another contract and he will get another chance. Look at Stromile Swift or Darko. Big men tend to stick around.
When I heard Curry saying that he had to pull Amir for forgetting plays I knew something was wrong. Especially with how simple and basic Curry's strategy was.
I voted minor bench player in the first poll as either I never saw what the others saw in him, or I just knew that he wasn't going to get the PT to be any better than what he was showing us. With that being said, I hope he moves up the ladder, but not that many players who jumped from high school to the NBA and who were taken near the end of the second round ever turn out to be career superstars. I abstained from the second question...
I never had confidence in Amir as a regular player. He had just signed a 3 year contract and I just figured he'd last that long with no new contract. That's why I said 3 and out. Actually, I thought Hermann would last more than three years.
sheed had to go. We need to move Rip, too, as he doesn't want to be here, and we got Ben Jordan now. If we don't figure out the log jam we win 30 games MAX. if we turn Rip into a big we might go .500. We have no starting or backup center. We have Ben Wallace. We have a rookie coach. Again. we have no PG. get your puke bags ready.
What do you mean by better? Will they try harder than last year? Probably yes. Will they sometimes play Ben Wallace style defense? Maybe yes. Will they get better as the season goes on or fade away like last year? Probably better. If they sneak into the first round of the playoffs will they put up a fight or roll over? Probably fight. Will they be fun to watch or will I have to turn the sound off to even make it through the game? I'm guessing fun. Could this Octobers team beat last Octobers team? Probably not. Do they have enough experience together to get deep in the playoffs? No, and last year they did. For me, I'll take a team getting better over a team getting worse anytime.
Just something I was thinking of... Will Bynum was a nobody at the start of last season. By that I mean that we didn't draft him, he had no hype, he wasn't getting paid much, and he wasn't expected to get any playing time at all. Yet, he actually performed at a surprisingly high level when given a chance and ended up becoming our primary backup PG forecasted for this season. In many ways, he outplayed Stuckey in long stretches last season. Who was the last guy to pull something like this off in the Pistons' system?
Ben Wallace: BW started in 81 games for Orlando the year prior. He was their top rebounder, 3rd in blocks, 3rd in steals, 2nd in FG%, and got more playing time than all but 2 other players on that team. We traded Grant Hill + Atkins for him. So there is some hype right there. When he came to Detroit, he went straight into the starting lineup on day one, with 38 minutes. He started in 80 games out of 80 appearances that year with 34.5 mpg. Mike James: Pistons press release: "James, 28, appeared in 55 games (all as a starter) for the Celtics this season, averaging 10.7 points, 3.2 rebounds, 4.4 assists and 1.27 steals in 30.6 minutes. The third-year guard comes to Detroit with career averages of 8.4 points, 2.3 rebounds, 3.4 assists and 23.8 minutes in 148 career NBA games (63 as a starter)." We traded Terry Mills, Rebraca, Sura, Atkins, Hunter, and the picks that turned into Tony Allen and Josh Smith in order to complete that trade for him and Sheed. My only point is that as far as I can tell, Bynum is the only player in recent memory to crack our rotation out of nowhere. He had only played in a handful of NBA games and then had a 3-year gap. After his first breakout game, here was Curry's quote: Found money. That should be Joe's nickname for WB.
Gotcha TaS. I was going with the "undrafted" angle but I see what you're saying. ...Didn't Michael Curry (the binary player, not the tablecloth clad coach) sorta come outta nowhere?


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Acne: Should I take isotretinoin for severe acne?
Acute bronchitis: Should I take antibiotics?
ADHD: Should my child take medicine for ADHD?
Allergies: Should I take allergy shots?
Allergies: Should I take shots for insect sting allergies?
Allergy shots (immunotherapy) for allergic rhinitis
Allergy shots (immunotherapy) for asthma
Allogeneic stem cell transplant
Alzheimer's disease: Should I take medicines?
Alzheimer's or other dementia: Should I move my relative into long-term care?
Amyotrophic Lateral Sclerosis (ALS)
Anger, Hostility, and Violent Behavior
Angioplasty for coronary artery disease
Angioplasty for peripheral arterial disease of the legs
Angioplasty with stent placement for heart attack and unstable angina
Aortic valve stenosis: Should I have surgery?
Arthritis: Should I have knee replacement surgery?
Arthritis: Should I have shoulder replacement surgery?
Atherectomy for coronary artery disease
Atrial fibrillation: Should I take anticoagulants to prevent stroke?
Atrial fibrillation: Should I try electrical cardioversion?
Autologous stem cell transplant
Autopsy: Should I have an autopsy done on my loved one?
Barrier methods of birth control
Bed-wetting: Should I do something about my child's bed-wetting?
Bed-wetting: Should my child see a doctor?
Behavioral methods for urinary incontinence
Behavioral therapies for urinary incontinence in men
Blocked tear ducts: Should my baby have a probing procedure?
Blood transfusions for sickle cell disease
Blood transfusions: Should I bank blood before surgery?
Bone marrow transplant for sickle cell disease
Brace (orthotic) treatment for scoliosis
Brandt-Daroff exercise for vertigo
Breast cancer risk: Should I have a BRCA gene test?
Breast cancer: Should I have breast reconstruction after a mastectomy?
Breast cancer: Should I have breast-conserving surgery or a mastectomy for early-stage cancer?
Breast cancer: Should I have chemotherapy for early-stage breast cancer?
Breast cancer: What should I do if I'm at high risk?
Breast-feeding: Should I breast-feed my baby?
Breech Position and Breech Birth
Bruises and Blood Spots Under the Skin
Bunions: Should I have surgery?
Carpal tunnel syndrome: Should I have surgery?
Cataracts: Should I have surgery?
Catheter ablation for a fast heart rate
Catheter ablation for atrial fibrillation
Catheters for urinary incontinence in men
Chemonucleolysis for herniated disc
Chronic Lung Disease in Infants
Circumcision: Should I keep my son's penis natural?
Clotting factor replacement for hemophilia
Cognitive-behavioral therapy for eating disorders
Cognitive-behavioral therapy for pain management
Colon cancer: Which screening test should I have?
Complementary medicine: Should I use complementary medicine?
Confusion, Memory Loss, and Altered Alertness
Constipation, Age 11 and Younger
Constipation, Age 12 and Older
Continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea
Cryotherapy (cryosurgery) for genital warts
Deep brain stimulation for Parkinson's disease
Depression: Should I stop taking my antidepressant?
Depression: Should I take an antidepressant?
Depression: Should I take antidepressants while I'm pregnant?
Depression: Should my child take medicine to treat depression?
Developmental Dysplasia of the Hip
Diabetes: Should I get an insulin pump?
Diabetes: Should I get pregnant?
Diabetes-Related High and Low Blood Sugar Levels
Dizziness: Lightheadedness and Vertigo
Dupuytren's disease: Should I have hand surgery?
Ear Canal Problems (Swimmer's Ear)
Ear infection: Should I give my child antibiotics?
Ear Problems and Injuries, Age 11 and Younger
Ear Problems and Injuries, Age 12 and Older
Ear problems: Should my child be treated for fluid buildup in the middle ear?
Electrical cardioversion (defibrillation) for a fast heart rate
Electrical cardioversion for atrial fibrillation
Electrical stimulation for urinary incontinence
Electroconvulsive therapy (ECT)
Electrolysis for removing hair
End of life: Should I stop treatment that prolongs my life?
End-of-life care: Should I have artificial hydration and nutrition?
End-of-life care: Should I receive CPR and life support?
End-of-life care: Should I stop kidney dialysis?
Endometriosis: Should I have a hysterectomy and oophorectomy?
Endometriosis: Should I use hormone therapy?
Enlarged prostate: Should I have surgery?
Enlarged prostate: Should I take medicine?
Erection problems: Should I take medicine?
Erection problems: Should I try injection treatments?
Exercise and physical therapy for tennis elbow
Exposure to Sexually Transmitted Diseases
External cephalic version (version) for breech position
Extracorporeal shock wave lithotripsy (ESWL) for kidney stones
Fertility problems: Should I be tested?
Fertility problems: Should I have a tubal procedure or in vitro fertilization?
Finger, Hand, and Wrist Injuries
Finger, Hand, and Wrist Problems, Noninjury
Flu shots: Should I get a flu shot?
Flu: Should I take antiviral medicine?
Gallstones: Should I have gallbladder surgery?
Gamete and zygote intrafallopian transfer (GIFT and ZIFT) for infertility
GERD: Which treatment should I use?
Hair loss: Should I take medicine to regrow hair?
Hammer, claw, or mallet toe: Should I have surgery?
Head Injury, Age 3 and Younger
Headaches: Should I take medicine to prevent migraines?
Headaches: Should I take prescription medicine for tension headaches?
Healthy aging: Is it time to stop driving?
Hearing loss: Should I get a hearing aid?
Heart attack: Should I take daily aspirin to prevent a heart attack or stroke?
Heart disease risk: Should I have a coronary calcium scan?
Heart disease: Should I have an angiogram?
Heart disease: Should I have angioplasty for stable angina?
Heart disease: Should I have bypass surgery?
Heart failure: Should I get a pacemaker?
Heart failure: Should I get an implantable cardioverter-defibrillator (ICD)?
Heart problems: Should I have catheter ablation?
Heart valve problems: Should I choose a mechanical valve or tissue valve to replace my heart valve?
Hemophilia: Should I have regularly scheduled or on-demand clotting factor replacement?
Hemorrhoids: Which treatment should I use?
Hepatitis B and C: Should I be tested?
Hepatitis B: Should I take antiviral medicine for chronic hepatitis B?
Hepatitis C: Should I take antiviral medicine?
Herniated disc: Should I have surgery?
High blood pressure: Should I take medicine?
High cholesterol: Should I take statins?
Hip Injuries, Age 11 and Younger
Hip Injuries, Age 12 and Older
Hip Problems, Age 11 and Younger
Hip Problems, Age 12 and Older
HIV: Should I start taking antiretroviral medicines for HIV infection?
HPV: Should my daughter get the vaccine?
Hyperbaric oxygen therapy for carbon monoxide poisoning
Hypoglycemia (Low Blood Sugar) in People Without Diabetes
Hysterectomy and oophorectomy: Should I use estrogen replacement therapy (ERT)?
Hysterectomy: Should I also have my ovaries removed?
Immunotherapy for allergies to insect stings
In vitro fertilization for infertility
Infertility: Should I have treatment?
Infrared photocoagulation for hemorrhoids
Inguinal hernia: Should I have surgery now, or should I wait?
Insect Bites and Stings and Spider Bites
Insemination procedures for infertility
Insomnia: Should I take sleeping pills?
Intracytoplasmic sperm injection for infertility
Intrauterine device (IUD) for birth control
Intrauterine fetal blood transfusion for Rh disease
Irritable bowel syndrome: Should I have tests for IBS symptoms?
Jaundice in Newborns (Hyperbilirubinemia)
Kidney failure: What type of dialysis should I have?
Laser photocoagulation for diabetic retinopathy
Laser treatment for varicose veins
Low back pain: Should I have an MRI?
Low back pain: Should I have spinal manipulation?
Male Genital Problems and Injuries
Mechanical devices for urinary incontinence in women
Meniscus tear: Should I have a diagnostic test (MRI or arthroscopy)?
Meniscus tear: Should I have surgery?
Miscarriage: Should I have treatment to complete a miscarriage?
Multiple pregnancy: Should I consider a multifetal pregnancy reduction?
Multiple Pregnancy: Twins or More
Multiple sclerosis: Should I start taking medicines for MS?
Nail infection: Should I take antifungal pills?
Nausea and Vomiting, Age 11 and Younger
Nausea and Vomiting, Age 12 and Older
Necrotizing Fasciitis (Flesh-Eating Bacteria)
Nonsurgical nail removal for fungal nail infections
Obesity: Should I have weight-loss surgery?
Obesity: Should I take weight-loss medicine?
Obesity: Should I use a diet plan to lose weight?
Obsessive-compulsive disorder: Should I take medicine for OCD?
Osteoarthritis: Should I have hip replacement surgery?
Osteoporosis: Should I have a dual X-ray absorptiometry (DEXA) test?
Osteoporosis: Should I take bisphosphonate medicines?
Ovarian cancer: Should I have my ovaries removed to prevent ovarian cancer?
Oxygen treatment for chronic obstructive pulmonary disease (COPD)
Pacemaker for atrial fibrillation
Panic disorder: Should I take medicine?
Pap test: Should I have colposcopy if my Pap test shows minor cell changes?
Pelvic floor (Kegel) exercises for urinary incontinence in women
Pelvic organ prolapse: Should I have surgery?
Percutaneous nephrolithotomy or nephrolithotripsy for kidney stones
Peripheral arterial disease: Should I have surgery?
Photodynamic therapy for age-related macular degeneration
Phototherapy for atopic dermatitis
Physical rehabilitation for ACL injuries
Physical therapy for TM disorders
Plantar fasciitis: Should I have surgery for heel pain?
PMS: Should I try an SSRI medicine for my symptoms?
Polymyalgia Rheumatica and Giant Cell Arteritis
Pregnancy: Should I bank my baby's umbilical cord blood?
Pregnancy: Should I have an early fetal ultrasound?
Pregnancy: Should I have an epidural during childbirth?
Pregnancy: Should I have CVS (chorionic villus sampling)?
Pregnancy: Should I have the maternal serum triple or quadruple test?
Pregnancy: Should I try vaginal childbirth after a past C-section (VBAC)?
Problems After Delivery of Your Baby
Prostate cancer screening: Should I have a PSA test?
Prostate cancer: Should I have radiation or surgery for localized prostate cancer?
Psoralen plus ultraviolet light therapy (PUVA) for atopic dermatitis
Pulmonary rehabilitation for chronic obstructive pulmonary disease (COPD)
Quitting smoking: Should I use medicine?
Radiation therapy for bladder cancer
Radiation therapy for cancer pain
Radiation therapy for endometrial cancer
Radiation therapy for lymphoma and leukemia
Radiation therapy for nonmelanoma skin cancer
Radiation therapy for prostate cancer
Radiation therapy for testicular cancer
Radiation treatment for melanoma
Radioactive iodine for hyperthyroidism
Respiratory Problems, Age 11 and Younger
Respiratory Problems, Age 12 and Older
Ringing in the Ears (Tinnitus)
Root planing and scaling for gum disease
Rotator cuff problems: Should I have surgery?
Rubber band ligation for hemorrhoids
Sclerotherapy for varicose veins
Seasonal Affective Disorder (SAD)
Semont and Epley maneuvers for vertigo
Sexual Abuse or Assault (Rape)
Shoulder Problems and Injuries
Sinusitis: Should I have surgery?
Sinusitis: Should I take antibiotics?
Sleep apnea: Should I have a sleep study?
Sleep apnea: Should I have surgery?
Sleep Problems, Age 12 and Older
Sore throat: Should I take antibiotics?
Spinal cord stimulation for chronic pain
Stroke: Should I have carotid endarterectomy?
Stroke: Should I move my loved one into long-term care?
Swollen Glands and Other Lumps Under the Skin
Tennis elbow: Should I have surgery?
TM disorder: Should I have surgery for jaw pain?
Toe, Foot, and Ankle Problems, Noninjury
Tonsillitis: Should my child have a tonsillectomy?
Ulcerative colitis: Should I have surgery?
Umbilical hernia: Should my child have surgery?
Urinary Problems and Injuries, Age 11 and Younger
Urinary Problems and Injuries, Age 12 and Older
Uterine fibroid embolization (UFE)
Uterine fibroids: Should I have surgery?
Uterine fibroids: Should I have uterine fibroid embolization?
Uterine fibroids: Should I use GnRH-a therapy?
Vacuum devices for erection problems
Vaginal delivery in breech position and breech birth
Vaginal yeast infection: Should I treat it myself?
Vagus nerve stimulator for epilepsy
Watchful waiting (surveillance) for non-Hodgkin's lymphoma
Watchful waiting for prostate cancer


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Maritime Noon | Apr 2, 2013 | 52:49
Ferry Search, Insurance and Credit Rating, Terry Punch, Ashfield Feedback
RCMP divers continue the search for a car that drove off the Englishtown Ferry last week. Relatives of a missing Nova Scotia man watch and wait for answers from the search. New Brunswick's consumer advocate for insurance speaks out against the practice of


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Brand: | Airfix |
Product name: | 42nd Highlander (Black watch) |
Product number: | C102S |
Scale: | 54mm |
Type: | Full kit |
Released: | 1971 | Initial release - new tool |
The history of this Napoleonic Wars-kit in scale 54mm visualised on the product timeline
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full-length portrait of beautiful young blond woman on couch with shopping bags and gift in hands
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text:
This is a discussion on Opinion Piece : Do We Value Guns More Than Children? within the In the News: The Good, the Bad and the Ugly forums, part of the The Back Porch category; Originally Posted by 9MMare Somebody's children are killing people. I say restrict their children, not our weapons. Examine how we are creating more (?) of ...
I bought my two kids with rifles and pistols .I took the mystery out of themsnd let them go to the range with me. By age 10 my boy had his own 22 and 410 shotgun.
When he graduated from middle school my wife and I purchased m-1 grand as he really wanted one as this is when Band of Brothers had come out!He join his schools rifle team and qulified expert!This is one thing father and son liked you did together.I never pushed it on him .
Saying we value guns more than children is a straw man argument. If we really valued our children we wouldn't trap them in buildings and then put up signs inviting criminals to massacre them. "Hey you with the gun, here's a whole campus where no one can challenge you because no one but you is allowed to carry a gun"


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Maid Breaks Leg in Fall at Park Ave. Penthouse
By Aidan Gardiner on September 17, 2012 11:14am
UPPER EAST SIDE — A maid slipped, fell, and broke her leg inside a posh Park Avenue penthouse, according to the FDNY.
A source said that the maid had just arrived at work at approximately 9 a.m. when she fell on some stairs in an apartment at 812 Park Avenue.
The building is home to Edgar Bronfman Jr. — an heir to the Seagram liquor empire and former chair of Warner Music — who reportedly bought a 6,500 square foot penthouse at the building in 2011, according to NYC Department of Finance Records. The Observer described the apartment as a five-bedroom triplex.
The woman was transported to Lenox Hill Hospital.


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'I have a dream': Your stories 50 years on
This August it will be 50 years since the American civil rights leader Martin Luther King delivered his 'I have a dream' speech. What effect has that historic moment had on your life?
Dr King grew up in Atlanta under a strict system of racial segregation, which he described in a televised interview for the BBC in 1963.
On 28 August 1963 more than 200,000 Americans joined a march on Washington DC demanding equal justice for all citizens under the law.
On that day, the interracial crowd heard Martin Luther King deliver his famous speech, predicting a time when freedom and equality for all would become a reality in the US.
In 1964 Congress passed the Civil Rights Act outlawing all forms of discrimination against racial, ethnic, national and religious minorities, and outlawing discrimination against women in the US.
Here, the British Poet Benjamin Zephaniah explains what the speech means to him, including why he thinks it was made, how the audience reacted, plus an analysis of its delivery.
What impact has 'I had a dream' had on your life? Do you know anyone who took part in the march? Have you been involved in any civil rights protests? Do you have any links to Martin Luther King?
Please send us your stories connected to Martin Luther King's 'I have a dream' speech.
Send your pictures and videos to email@example.com or text them to 61124 (UK) or +44 7624 800 100 (International). If you have a large file you can upload here.


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Bodyline: 80 years of cricket's greatest controversy
As Australian batsman Bert Oldfield collapsed, his skull fractured by a lightning-fast ball, the booing from the 50,000-strong Adelaide Oval crowd became a deafening howl.
The England players, mouths dry with fear, looked for escape routes - or even potential weapons - in case the mob fell on them.
Bowler Harold Larwood, the focus of the fury, turned to team-mate Les Ames. "If they come," he said, "you can take the leg stump for protection - I'll take the middle."
Never before or since that moment, 80 years ago to the day, on 16 January 1933, had cricket - and arguably any other sport - seen a contest which fired such anger, which reached so far and echoed for so long, as the Bodyline tour.
"In Australia to this day, the word Bodyline carries the stench of underhand or unsportsmanlike behaviour; with the series regarded as Australian cricket's most controversial," said David Studham from the Australian National Sports Museum.
The view of the MCC, which organised the tour, is slightly different. The curator of its museum, Adam Chadwick, said: "Was Bodyline unsportsmanlike? By the standards of the day, yes. By the standards of now, it was a stroke of genius."
'Devastatingly fast'At the beginning of the 1930s, the MCC - Marylebone Cricket Club - still ruled the cricketing world from its seat at Lord's in London.
But it had a problem, in the shape of batting phenomenon Don Bradman.
During their 1930 tour of England, Australia - the arch rivals - had dominated the home bowlers, with Bradman averaging a staggering 139.14.
The MCC looked to austere amateur player Douglas Jardine for an answer, making him England captain.
Jardine believed Bradman struggled against balls which bounced into his chest and formed a tactic to exploit this. But the plan needed the right bowler, and that bowler was former Nottinghamshire miner Harold Larwood.
Duncan Hamilton, Larwood's biographer, said: "He had two things. Firstly he was incredibly accurate, he claimed never to have bowled a wide in his career, and accuracy was essential to Bodyline.
"Secondly he was devastatingly fast. All his contemporaries said he was the quickest they had faced. At certain times during that series he must have got close to, if not passed, the 100mph (160km/h) mark.
"Every fast bowler who sees that old footage says, 'Wow, that's quick!'."
Jardine's plan was to use what was known in England as leg theory. Bowling fast, high-bouncing deliveries on the line of the leg stump of the wicket - where a batsman would usually stand.
The batsman had three choices: to move but risk exposing his wicket, to play the ball with his bat and face being caught by a ring of close fielders, or try to duck and risk painful blows.
The tour began in earnest at Sydney in December 1932, ironically without Bradman playing. Bodyline brought England victory.
Bodyline introduced a previously unspoken element into Test cricket - namely the physical intimidation of the batsman.
The placement of fielders, deliberately positioned to catch the ball from batsmen protecting themselves from short, fast deliveries aimed at the ribs and throat, was entirely legal at the time, but seriously threatened the code of sportsmanship that is so central to cricket.
That said, the Australian administrators - who made such a meal of Jardine's tactic at the time - were noticeably quiet when their own fast bowlers Dennis Lillee and Jeff Thomson were terrifying batsmen with short-pitched bowling in the 1970s.
The authorities acted swiftly after the Bodyline tour to limit the placing of fielders in catching positions on the leg side in an attempt to deter a repeat of the tactic, and also brought in a restriction of the number of bouncers that can be bowled in a single over.
But after Lillee and Thomson, the West Indies' formidable pace attack of the late 1970s and 80s also proved that skilful, intimidatory fast bowling is every bit as effective as Bodyline, even with field restrictions and after the introduction of helmets.
Complaints about the tactic quickly appeared. As the bruises and wickets mounted, the disquiet turned to anger, with claims batsmen were being physically targeted.
'Vicious' bowlingDespite Australia levelling the series at the second match in Melbourne, the repeated blows to lightly protected players attracted outraged headlines.
Some batsmen endured hours of punishment and even Bradman looked unsettled.
Mr Studham said: "The tactics employed by Jardine roused intense passions, as they were so out of accord with anything that had previously happened on the cricket field.
"Targeting the bowling along the line of the batsman's body was regarded by the Australian crowds as vicious, unsporting and especially after repeatedly battering the batsmen, 'hitting a man when he was down and certainly no part of cricket'."
Police protectionWith everything to play for, and feelings running at fever pitch, the Adelaide match opened in front of packed stands.
Cricket bible Wisden would later call it "probably the most unpleasant Test ever played".
Australian captain Bill Woodfull was left staggering after being struck just above the heart by Larwood.
The booing lasted for three minutes, despite the fact England had not yet deployed Bodyline tactics in the match.
That would change though, moments later, when Jardine called out to Larwood: "Well bowled Harold," and set the fielders in the hated Bodyline formation. Police had to be deployed on the boundary.
The next day, Oldfield had his skull cracked and Larwood had to be escorted from the ground.
What is fair play?
- In ethics, the concept of fairness involves treating everyone equally and impartially
- Fair play is usually understood to mean using only tactics that are in accord with the spirit of the sport
- Fair play is not just about keeping to the rules, but also self-control, courage and persistence
Source: BBC Religion & Ethics
It was almost inevitable the problems would overflow from the playing field. But no-one could have predicted it would lead to three events then unthinkable in cricket.
'Hysterical' reactionMCC tour manager Pelham Warner, seeking to smooth relationships, was sent packing by the normally placid Woodfull with what were, for some years, the 25 most famous words in sport.
"I don't want to see you, Mr Warner. There are two teams out there. One is trying to play cricket and the other is not."
The comment, made in the previously sacrosanct dressing room, was then leaked to the press.
The next day, Australian Board of Control for International Cricket sent a cable to the MCC which described England's tactics as "unsportsmanlike", the ultimate taboo for guardians of the game.
Mr Chadwick said: "The MCC reacted with incredulity to the Australian messages that the tactics were unsportsmanlike and they felt it was really out of the question that an MCC team led by a gentleman of Douglas Jardine's character could possibly behave in such a manner.
"The archives really do show the feeling was 'Oh, the Australians are being a bit hysterical about it'."
But the situation spiralled. Jardine threatened to withdraw his team from the remaining two matches unless the allegation was retracted.
Stoked by newspaper reports, each country backed its own players.
The standoff only ended when Australian Prime Minister Joseph Lyons told the cricket board a British boycott of Australian goods could cripple the country.
England won the series 4-1. Bradman's batting average was cut to a merely excellent 56. But the shock lasted for years.
'National disdain'Mr Studham said he felt Bodyline was one of those sporting "rite of passage" stories all Australian children learn about.
"The on-field tactics and resulting carnage at the third Test in Adelaide split already strained relations between the teams, the game's governing authorities, and even threatened to split the governments.
"Start Quote
End Quote Duncan Hamilton Larwood biographerHe was totally betrayed by the establishment"
"While perfectly legal at the time, it left lasting ill-feeling in Australia where it was seen to be outside the spirit of the game.
"The fact that a few years later the laws of cricket were amended to ban Bodyline bowling contributed greatly to its continuing national disdain."
Mr Chadwick said: "The MCC did not have any advance warning of the tactics which Jardine was using and wasn't really aware of the impact - all they were getting was newspaper reports and telegraph messages of the score.
"When they saw it for themselves they realised this really wasn't the sort of cricket they had always set themselves up to promote as containing the best values of Britishness and gentlemanly fair play."
Jardine retired from first class cricket the following year. Larwood's agony was more extended.
Hated heroInjured through over-bowling, he was then stunned at his treatment by cricket's hierarchy.
Mr Hamilton said: "He was totally betrayed by the establishment. They treated him like toxic waste.
"He was asked to apologise and he rightly refused, saying he had done what his captain had asked. He got no support for his injury.
"On his return to Nottingham he was met by cheering crowds 10,000-strong. He went from that to being vilified. The whole thing was a tragedy."
Larwood never played for England again. On the advice of some of his old Bodyline foes, he emigrated to Australia in 1950 - becoming firm friends with Bert Oldfield.
He was appointed MBE in 1993, at the age of 88. A statue of him was unveiled in Kirkby-in-Ashfield, close to his birthplace, in 2002.


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Do you think wearing on-body cameras on duty should be mandatory?
The Russell County Sheriff's Department and Phenix City Police Department (in Alabama) are using a Justice Department grant to add in-car video to patrol vehicles. The agencies are upgrade to new Digital Ally camera gear and replacing Sony cancorders mounted to the dashboards. The new systems will improve reliability, deliver better quality video, and free up space in the squad car.
Police agencies have come to depend on in-car video systems to capture each shift on camera. Not only do these devices provide a way to document events that take place in and around patrol cars, but new technology makes the recorded proof even more ironclad when scrutinized by defense attorneys and jury members.


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Fatality Assessment and Control Evaluation (FACE) Program |
Youth Laborer Dies in Trench Collapse - Michigan |
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SummaryA 17-year-old male laborer (the victim) died and a coworker was injured after one of the unprotected walls (i.e., no shoring, shielding or adequate sloping) of the trench they were working in collapsed, striking and partially burying them with soil. The day before the incident the excavator operator had removed the trench shield used during the sewer installation project to facilitate the removal of broken sewer pipes. When work was resumed the next day, the trench shield was not replaced, and the victim and a coworker (pipe setter) went into the unprotected trench to replace two sections of pipe and to check the grade of the sewer line with a grade pole. While they were placing the grade pole inside the terminal end of the sewer line, a section of the trench wall caved in, striking and burying the victim to his mid-chest and his coworker to his knees. The foreman, who had been working above the trench at ground level, called 911 at 9:39 a.m. and requested emergency medical services (EMS). EMS, law enforcement, and the fire department personnel arrived within 5 minutes of the 911 call. The Fire Marshall assumed responsibility for rescue operations and site safety and, in his role as Incident Commander (IC), assigned Operations Officer duties to one of the fire fighters. The Operations Officer, realizing that the trench walls remained unstable and hazardous, directed coworkers, who had jumped into the trench to render assistance, to leave the trench until fire fighters could obtain the necessary protective systems to ensure safe rescue operations. Coworkers refused to leave the trench and continued digging to free the trapped workers. The Operations Officer asked law enforcement personnel to remove the foreman from the incident site when he demanded that EMS and fire fighters go into the unprotected trench. The foreman was removed from the incident site. While fire fighters were waiting for the arrival of protective systems, they set ground pads (sheets of plywood) along the side opposite the collapse to provide paramedics with a more stable point from which to lower an oxygen tank and oxygen administration equipment. Coworkers placed an oxygen mask on the victim. By this time he had become ashen in color and was semi-conscious, with a weak pulse and labored respirations. Both the victim and his injured coworker were freed by their coworkers, placed on backboards, and carried to the shallow east end of the trench. With assistance from fire fighters working above at ground level, coworkers lifted the victim and his injured coworker to fire fighters. They in turn carried the injured workers to an area where paramedics were standing by. Both workers were treated by paramedics and transported by ambulance to a local hospital where the injured coworker was admitted in serious condition and subsequently released. The victim underwent emergency surgery, experienced a cardiac arrest, and died at 2:03 p.m., approximately 5 hours following the incident. NIOSH investigators concluded that, to help prevent similar occurrences, employers should:
Additionally, NIOSH recommends
IntroductionOn November 10, 1999, a 17-year-old male laborer (the victim) died and a coworker was injured after one of the unprotected walls (i.e., no shoring, shielding or adequate sloping) of the trench they were working in collapsed, striking and partially burying them with soil. On November 15, 1999, officials of the Wage and Hour Division of the Department of Labor notified the Division of Safety Research (DSR) of this fatality. On November 22, 1999, a DSR occupational safety and health specialist conducted an investigation of the incident. The incident was reviewed with personnel from the U.S. Department of Labor Wage and Hour Division, Michigan Department of Labor, and the medical examiner's office. Neither the victim's work site employer nor his administrative employer, a Professional Employer Organization (PEO), were available for interview. The construction site where the incident occurred was visited and photographs obtained during the investigation. In this incident, the victim's work site employer was a construction contractor and his administrative employer was a PEO. The process by which the co-employers hired the victim was as follows. The construction contractor hired the victim. The PEO then reviewed his application, performed the data entry, and then put the victim on the PEO's payroll. The construction contractor had approximately 31 years of experience in construction-related activities. He had owned his business for approximately 28 years. In 1996, the contractor entered into a contract with a PEO, making the PEO the administrative employer for the company's employees. At the time of the incident the contractor had 25 full-time employees, including the victim, working under this co-employer arrangement. According to the Michigan Department of Labor, the construction contractor had a safety program but had not implemented the program or provided the victim with safety training. The company had the victim sign a document acknowledging his receipt of the Michigan Occupational Safety and Health Administration (MIOSHA) Standard Handbook which outlines the requirements for protective support systems in excavations. The company's foreman held weekly tool box talks with the crew which included trench safety but the victim had not yet taken part in these talks. The incident occurred on the victim's second week of employment and his third day working at the incident site. This was the first fatality in the history of the construction company. The victim's co-employer was a PEO which provided administrative services to the construction company and its employees. Administrative services included a full-featured employee benefit and human resource program. The PEO had been in business for 70 years and employed approximately 38 administrative staff. According to the PEO's brochure, the PEO becomes a co-employer with the Client (another business entity) and provides a full-featured employee benefit and human resource management program. The brochure says in part that "we handle the employee paperwork and the administration. As the work site employer, you direct your staff's day-to-day activities, just like you always have. The difference is, we spend our time on things that always seem to take up your time." The brochure also indicates that the Client has the PEO's help with work site safety procedures, analysis of the work site, identification of potential problems, preparation of an employee safety manual, and assistance in utilizing these tools at the client's work site The Client Service Agreement initiated by the PEO and agreed upon by Client says that the Client agrees to comply at its expense with all safety, health, and work laws, regulations, directives and rules. Investigators were unable to determine whether there had been any services other than benefits services provided by the PEO to the victim or the construction contractor. This was the first fatality in the PEO's history. Back to TopInvestigationThe construction contractor was hired by a private industrial park development enterprise to install a sewer system on a 3.5-acre site. According to official reports, work had been ongoing at the site for several weeks, and approximately 200 feet of sewer line had been laid (see Figure 1). The sewer installation crew working at the site on the day of the incident consisted of five men including the victim. Also present at the site was a self-employed excavator operator who had been hired as a subcontractor by the construction contractor. His job was to dig the trench, lower sewer system components, move the trench box, and to refill the trench after the sewer system was in place. He was operating a 162-horsepower, diesel-powered, track-mounted hydraulic excavator which was manufactured after 1995.
On the day before the incident, the excavator operator struck two sections of pipe with the bucket of the hydraulic excavator and broke them as he compacted and leveled sand over a completed section of sewer line. When he tried to lift and remove the broken pipes, they broke off beyond the location of the trench shield. Because the excavator operator could not get the pipes out of the trench with the trench shield in place, he removed the trench shield, which had been used throughout the sewer line installation, and placed it approximately 20 yards to the south of the trench (see Figure 2). The excavator operator and the sewer line installation crew then quit work for the day.
When work resumed at approximately 7:30 a.m. the next morning, the excavator operator removed the broken pipe. He did not replace the trench shield before he lowered new sections of pipe into the trench. He then waited nearby with the hydraulic excavator running since his next task, after the line was repaired and properly aligned, would have been to lower a cement manhole into place. The victim and a coworker (pipe setter) went into the unprotected trench to set the two new sections of pipe. The trench was approximately 11 feet deep and 8 feet wide in the area in which they were working. After they had set the pipe, a coworker, working above them at ground level, handed them a grade pole. While they were placing the grade pole inside the end of the pipe to allow them to check the grade of the sewer line, a section of the unprotected trench wall 30 feet long by 11 feet high and several feet thick caved in (see Figure 3). A portion of this fallen section struck the victim and his coworker, burying the victim up to his mid-chest and his coworker up to his knees (see Figure 4).
The foreman called 911 at 9:39 a.m. and requested emergency medical services (EMS). In the meantime, two coworkers and the excavator operator jumped into the trench, and using shovels and their bare hands, tried to free the partially buried workers. EMS, law enforcement, and fire department personnel arrived within 5 minutes of the 911 call. The Fire Marshall assumed responsibility for rescue operations and for site safety and, in his role as Incident Commander (IC), assigned Operations Officer duties to one of the fire fighters. The Operations Officer, realizing that the trench walls remained unstable and hazardous, directed the victim's coworkers to leave the trench until protective systems could be installed, but the coworkers refused. The Operations Officer directed the victim's foreman to shut down all machinery while fire fighters made arrangements to obtain and install protective systems before effecting a rescue. The Operations Officer asked law enforcement officers to remove the foreman from the incident site when he demanded that fire fighters and EMS enter the trench without the benefit of protective systems. A police officer removed the foreman from the immediate area. While waiting for another fire department unit to deliver protective systems, fire fighters obtained plywood from a nearby business and placed it on the spoil side (north) of the trench opposite the area where the trench wall had collapsed. Using the plywood ground pads for support, paramedics lowered an oxygen cylinder and a non-rebreather mask to the victim's coworkers who placed the mask on the victim. At this time, the victim was ashen gray in color and semi-conscious, with a weak pulse and labored respirations. The injured coworker was conscious, verbalizing his pain, and had normal skin color. Within 22 minutes and before protective systems had been placed in the trench by fire fighters, coworkers freed both workers and, after securing them on backboards, carried them to the east end of the trench. In the meantime, fire fighters placed a ladder into the east end of the trench where the trench depth was approximately 3 to 4 feet deep. Coworkers slid the backboards, on which the victims had been secured, up the ladder to fire fighters who reached down from above to receive them. The injured workers were treated by paramedics and transported via ambulance to a local hospital. The injured coworker was admitted in serious condition and subsequently recovered. The victim underwent emergency surgery, experienced a cardiac arrest, and died at 2:03 p.m., approximately 5 hours following the incident. Back to TopCause of DeathThe Medical Examiner listed the cause of death as abdominal trauma. Recommendations and DiscussionRecommendation #1: Employers should ensure that workers are protected at all times from potential cave-ins by an adequate protective system.1, 2Discussion: 29 CFR 1926.652 (a) (1) states that "each employee in an excavation shall be protected from cave-ins by an adequate protective system." MIOSHA R408.40941 (1) requires a similar level of protection. In this incident, reports indicate that an adequate protective system, a heavy-duty trench shield, had been placed in the trench during the pipe-laying process. It had been removed in order to remove pipes that had been broken during soil compacting. When work conditions change and necessitate the temporary removal of the protective system in use, employers must ensure that all workers are removed from the trench. Only when an appropriate protective system is again placed in the trench should workers be allowed to reenter the trench.
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Digital publisher Open Road is running a sale on its eBook collection. The company is selling select digital books for between $.99 and $4.99. The "50 Summer Steals" promotion is good across eBook retailers through July 12th.
Here are five handpicked books from Open Road's sale–you can find these titles at your favorite eBook retailer.
1. The Lords of Discipline by Pat Conroy: On sale for $4.
read more
During August, Harper Perennial is running a 20 eBooks for $20 promotion, selling a select set of titles for 99-cents at all major eBook retailers. The list includes: I am not myself these days by Josh Kilmer-Purcell, Bad Marie by M... Read Post
Digital publishing company Open Road Integrated Media has partnered with Good Books, an independent publisher specializing in Amish and Mennonite life, to turn a number of Good Books' titles into eBooks. Books included in the partne... Read Post
Digital publisher Open Road is running a sale on its enhanced eBook collection. For the next two weeks, the company has cut its eBook prices and is selling eBooks for between $.99 and $4.99. Books on sale include: Pat Conroy's The L... Read Post


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Photograph of 400X magnified image of biogas digestor sample. A strange spiraled type microbe seen (probably like left handed DNA helix). The microbe is shown with an arrow. Has anyone seen such microbial structure?
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Vincent, Dickson, and Daniel solve last week's case study, present a new one, and reveal how secreted proteins from a helminth prevent diabetes in mice. Hosts: Vincent Racaniello, Read More Hosts: Vincent Racaniello, Michael Schmidt, ... Read More This episode: Carbon monoxide-eating bacteria get modified to produce more useful products! (16 MB, 17.5 minutes) Show notes: ... Read More
Strain: Pseudomonas aeruginosa PA14
Medium: M8 minimal medium agar plates Incubation Conditions: 48 hours at 37°C Pseudomonas aeruginosa is a gram-negative, rod-shaped and monoflagellated bacterium that has an incredible nutritional versatility. Swarming motility, a flagellum-dependent behavi... Read More Vincent, Dickson, and Daniel present a new case study, and discuss the effect of chronic malaria infection on wild warbler life span and telomere degradation. Hosts: Vincent Racaniello, Read More This episode: Bacteria from wastewater treatment sludge can produce lots of biodegradable plastic! (7.1 MB, 7.75 minutes)
Cyanobacteria could serve as a synthetic biology chassis that could be retooled for the production of biofuels, drugs or chemcials. So far, however, they have been held back by sluggish growth that makes it difficult to conduct the initial experiments needed to characterize their genetic and met...
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Presentation by Anthony S. Fauci, MD, Director, NIAID/NIH, Bethesda, MD, at the ASM Biodefense 2015 Meeting in Washington, D.C. on Feb 11, 2015.
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More than 15 million people in the United States live with food allergies that impact every meal they eat. For some, accidentally ingesting a snack that their body deems taboo can ignite a violent biological response. Every three minutes someone is rushed to the emergency room due to a food alle...
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In the largest longitudinal study of the microbiome to date, researchers from the Broad Institute of MIT and Harvard, Massachusetts General Hospital (MGH), and the DIABIMMUNE Study Group have identified a connection between changes in gut microbiota and the onset of type 1 diabetes (T1D). The st...
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Streptococcus pneumoniae cells are Gram-positive, lancet-shaped cocci. Usually, they are seen as pairs of cocci, but they may also occur singly and in short chains. In this photo a mucoid strain on blood agar showing alpha hemolysis (green zone surrounding colonies). Note the zone of inhibition ...
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Rivers and streams could be a major source of antibiotic resistance in the environment.
The discovery comes following a study on the Thames river by scientists at the University of Warwick's School of Life Sciences and the University of Exeter Medical School. The study found that greater n... Read More
Since the 1950s farmers have fed antibiotic growth promoters (AGPs) to livestock. Overusing these substances can create superbugs, pathogens that are resistant to multiple drugs and could be passed along to humans. Mindful of that, companies such as Perdue Farms have stopped using the drugs to m...
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Here's an undeniable fact: In samples collected from seven of New York's subway platforms, scientists discovered that we're surrounded in plumes of microbes wafting off other people's skin. Here's another undeniable fact: Those bacteria colonize all of our glands and follicles and the entire epi...
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For more than a year, Cornell University's Christopher Mason and his team of researchers have been identifying bacteria in the New York City subway system. And some of the findings might surprise you. Photo: Katie Orlinsky for The Wall Street Journal
Read More This episode: Programming bacteria to sense and keep genomic records of environmental inputs! (15.9 MB, 17.4 minutes) Show notes:
According to the Review on Antimicrobial Resistance commissioned by the UK Prime Minister, failing to address the growing problem of drug-resistant infections could cause 10 million deaths a year and cost up to $100 trillion USD by 2050.
Now, researchers from the Hebrew University of Jerusal... Read More |


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Daily Dish: July 5
Staff Report
July 5, 2006
See also:
Monday's Daily Dish
See also:
Today's Baseball Prospect Report
High Class A Lake Elsinore's offense provided plenty of fireworks Tuesday, hitting three homers in the Storm's 17-2 win at Inland Empire.
Third baseman Chase Headley had the line of the day for Lake Elsinore, going 3-for-4 with his 10th home run and his 19th double of the season. The Padres' second-round pick last year out of Tennessee already has four more bombs than his debut last season, when he batted .268/.375/.441 with six homers in 220 at-bats at short-season Eugene. Headley jumped straight to high Class A this season after finishing out last year with just four games at low Class A Fort Wayne.
So far this season, Headley is hitting .279/.371/.446 with 42 RBIs in 294 at-bats for the Storm.
"I've worked some on trying to get my hands out from my body a little bit more." Headley said. "Playing third base, I've been trying to work on my power a little more. I've never been a huge power guy before, but I think it's in there and we're trying to pull it out a little more.
"I know I'm not going to hit 50 home runs in the big leagues, but I can be a guy who hits 20 to 30 and hits for a decent average. So I've just done some little things to get my hands freed up a little bit and try to generate some more bat speed."
A switch-hitting third baseman, Headley is crushing from the left side, and struggling against lefthanders. Batting righthanded, the 22-year-old is hitting .200 with just eight extra-base hits. Compare that to when he's facing righthanders and it's an entirely different story--.326 with seven of his 10 homers and 14 of his 19 doubles have come hitting lefthanded. Interestingly, Headley's natural side is batting righthanded.
"Lefthanded right now I feel awesome, mainly because you just see so many more righthanded pitchers that I've found a real nice comfort zone from the left side," Headley said. "I'm still trying to adjust hitting righthanded because in college it was very rare that I got anything inside--everything was soft-away, soft-away and then maybe show in and then back out there. In the pro game, they'll come in a lot more and with the wood bat, that's giving me some trouble."
Defensively, it's also been a work in progress for Headley. He didn't play third until his freshman year at Tennessee, but made huge strides last year during instructional league and again this spring. He's fundamentally sound on the corner, with soft hands and an average, accurate arm. This season, he's committed 10 errors in 190 total chances (.947).
"I'm still learning, really," Headley said. "I'm working on some positioning things and just some techniques that you do differently than in the middle of the diamond. I think I'm getting better defensively just because I'm getting more experience and knowing more of what to expect and what's expected out of me playing that corner position. Those hot shots aren't so hot anymore because you start to see them a little bit better.
"I feel like I've made some strides in my lateral movement--I'm not going to be the fastest guy coming in on balls, but I think that improvement in my side-to-side movement has helped tremendously coming into this season."
And perhaps Headley's biggest asset is his makeup. A high school valedictorian and an academic all-American for the Volunteers, Headley already has a track record of making easy mental adjustments, even though he's in his first full season of pro ball.
"I try to do as much as I can to mentally prepare myself every day, mainly because I'm not quite as physically gifted as some of the guys I play against," Headley said. "I'm trying to get every advantage mentally as I can--keeping track of what different pitchers have done to me in the past or what other hitters do in certain situations against our guys so I can position myself better--I just try to apply myself and see if I can't pick something up and use it to benefit what I'm trying to do."
Rasmus Promoted
After he hit .310/.373/.512 in 303 at-bats in the low Class A Midwest League, the Cardinals have promoted outfielder Colby Rasmus for Quad Cities to Palm Beach of the high Class A Florida State League.
"I'm glad to see him go, but we'll miss him," Quad Cities manager Keith Mitchell told the Quad-City Times. "I think he saw it coming. The last few games I didn't think I saw the same Colby Rasmus at the plate that we had seen the previous few weeks.
"I think he was starting to wonder when it was going to happen, and it was starting to impact his game, so it was time for him to move on."
Rasmus was one of a quartet of outfielders drafted in the first round out of high school in 2005 who was flourishing in the Midwest League. The 19-year-old joined the Diamondbacks' Justin Upton, the Tigers' Cameron Maybin and the Reds' Jay Bruce to give the MWL one of the deepest pools of outfield prospects of any league in the minors.
At the time of his promotion, Rasmus was ninth in the league in hitting and fifth in slugging and extra-base hits.
The 28th overall pick last year from Russell County (Ala.) High, Rasmus' rise is in sharp contrast to Tyler Greene, the Cardinals other first-round pick of a year ago. Greene, the 30th overall selection, struggled horribly for Palm Beach this season as he hit .224/.308/.325 with 90 strikeouts in 268 at-bats before being reassigned to Quad Cities a few days ago.
• In Futures Game related news, Pirates lefthander
Tom Gorzelanny's
promotion to the big leagues has opened a spot for Pittsburgh reliever
Josh Sharpless
on the U.S. pitching staff. Sharpless, a 24th-round pick in 2003, started the season at Double-A Altoona where he allowed just two earned runs in 21 innings and was promoted to Triple-A Indianapolis. The righthander has been nearly as impressive in the International League, going 1-1, 2.11 with a 22-8 strikeout-walk ratio in 21 innings . . . BA correspondent
George King
of the New York Post reports the Yankees have agreed to terms with Brooklyn righthander
Dellin Betances
, who was taken in the eighth round of this year's draft. It's believed the Grand Street Campus High School product landed a signing bonus exceeding $1 million. He will report to Tampa and pitch in the Rookie-level Gulf Coast League. General manager
Brian Cashman
said Betances has the highest ceiling of any pitcher the Yankees drafted in 2006 . . . Dodgers third baseman
Andy LaRoche
, 22, has returned to the Triple-A Las Vegas lineup after missing two weeks with a slight tear in the labrum of his right shoulder. LaRoche is foregoing surgery for the injury, which he sustained in just his fourth PCL game in June 15. He's hitting .300/.391/.600 through his first 20 at-bats with Las Vegas . . . So far, so good for
Chris Iannetta
, 23, who's continued his hot hitting after a promotion to the PCL. The Rockies top catching prospect hit his second home run for Triple-A Colrorado Springs Tuesday--and collected two doubles--in just his eighth game. Iannetta had hit .321 with 11 home runs for Double-A Tulsa this season . . . Angels righthander
Nick Green
put together his fourth quality start in a row Tuesday, and picked up his first win since June 14 in Double-A Arkansas' 7-3 victory against Tulsa. Green, a 35th-round pick in 2004, allowed a pair of runs on six hits over 6 2/3 innings. Over his last four outings, Green is 2-0, 3.80 with 19 strikeouts in 26 innings. "He's been pretty solid for us," Travelers manager
Ty Boykin
told the Arkansas Democrat-Gazette. "He's got good tempo, he throws strikes, he keeps the ball down in the zone, he gets ground-ball outs, he gets the ball put in play early in the count--all the things we talk about throughout the organization about what we're trying to accomplish when we're on the mound." . . . Devil Rays outfielder
Josh Hamilton
went 1-for-3 with a double for short-season Hudson Valley in his first game back since returning from lengthy suspension. It was his first game since 2002 . . . Diamondbacks shortstop/second baseman/third baseman/first baseman/outfielder
Mark Reynolds
ran his hitting streak to 18 games for high Class A Lancaster. He clubbed his California League-leading 22nd home run in an 8-2 loss to High Desert, putting him one behind the overall minor league homer lead held by Triple-A Durham's
Kevin Witt
. Reynolds, a 16th-round pick out of Virginia in 2004, is also second in the Cal League with a .335 average and second behind teammate
Carlos Gonzalez
with 73 RBIs. Though he has gotten 111 of his 257 at-bats as a shortstop, he has shown off his versatility for the JetHawks by playing all over the infield and a bit in left field as well . . . After drafted in the 11th round this June,
Tyler Chambliss
was undecided whether to return to Florida State or sign with the Royals. "I weighed the risk and rewards of coming back, and I just thought the risks outweighed the rewards," Chambliss told the Suwanee Democrat. "I really thought about it, and my goal has always been to play major-league baseball, so why pass it up?" In his debut on Tuesday, the righthander looks to have made the decision. On a pitch count with Rookie-level Idaho Falls, Chambliss didn't allow a hit in his first four innings of professional baseball work. He struck out three in the no decision, as reliever
Harold Mozingo
would follow with a four inning, one-hit effort to land the victory . . . Following offseason shoulder surgery, lefthander
Dallas Braden
missed the first three months of the season. On Tuesday, Braden began his debut with the Arizona League A's, not allowing a run in two innings of work. Braden won 15 games in 2006 armed with a screwball that confused minor league hitters. Expectations are low this season following his surgery, but allowing just two hits and no walks in his two-inning return is certainly a step in the right direction.
Contributing: Matt Eddy, Aaron Fitt, Bryan Smith.


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How to create a contact form in Mambo
Mambo has a built in feature that allows you to add a contact form to your website. In this tutorial, we will learn how to create the contact form and add it to the sidebar menu in Mambo.
Steps to add a contact form
- Log into your Mambo Dashboard.
- Go to Components > Contacts > Manage items.
- Click New at the top right.
- Fill in the contact details. The name field will name the form in Mambo. The name field will not show on the website. The other information will display on the Contact page unless you hide the information in the parameters on the right.
- Save the changes.
- Now in the Contact manager, you will see the contact form you made in the list.
- Click New at the top right.
- In the Components section, click Link - Contact Item.
- On the Add Menu Item :: Link - Contact Item page, Fill in the details. In this case we are selecting the highlighted section in the snapshot to the right.
- Click Save at the top right.
Now the Feedback link will be in the menu to the left and the Contact form will display in the page like the snapshot to the right.
Continued Education in Course 102: Adding content to your Mambo site
You are viewing Section 5: How to create a contact form in Mambo
Section 4: Adding an iframe to a Mambo page
Section 6: Using Captcha in Mambo
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Adding content to your Mambo site
Adding content to your site | |
1. | How to Create a New Page in Mambo |
2. | Inserting an internal link in Mambo |
3. | Adding an Image to a Page in Mambo |
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Bali: Safari Wellness Spa
Photo: Elephant Safari Park Lodge
Every May, Condé Nast Traveler releases its Hot List, a collection of the best new hotels, spas, restaurants, and nightspots. Check the Daily Traveler every day for a new post from this year's list.
On an island brimming with five-star spas, try something completely different in Ubud--namely, one with 27 roaming elephants. The small granite-and-glass facility sits on the grounds of Aussie expat Nigel Mason's Elephant Safari Park Lodge, a 25-room Ubud property inside a Sumatran pachyderm sanctuary. With picture windows framing the herd's lush "living quarters," two modern suites are set up with treatment tables, massaging armchairs, showers, and soaking tubs. The full menu ranges from waxing and mani-pedis to aromatic Yon-Ka Paris facials ($58) and Balinese massages ($30). The Wild Yam Skin Nourishing Signature Ritual ($60) incorporates skin-firming local wild yam (as well as lemongrass, ginger, cinnamon, and mint) into a two-and-a-half-hour super-softening massage, scrub, body mask, and hot-bath medley (massages, $30).
Tel: 62-361-977884
Further reading:
* Elephant Safari Park Lodge
* Hot List 2008
* The Bali Guide
* Hot List on the DT


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What does WSAE stand for?
What does WSAE mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: WSAE.
We've found a total of 3 definitions for WSAE:
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WSAE | FM-106.9, Spring Arbor, Michigan | ||||
WSAE | Washington Society of Association Executives | ||||
WSAE | Written Self-Assessment Exam |
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"WSAE." Abbreviations.com. STANDS4 LLC, 2015. Web. 5 Mar. 2015. <http://www.abbreviations.com/WSAE>.


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Confrontation led to shooting death of man in rural Belgrade
WILLMAR -- Delbert Huber, 81, and Timothy Huber, 45, of rural Paynesville, drove to a rural Belgrade residence early Saturday morning, armed with a 303 British Enfield rifle, to confront Timothy Richard Larson, 43, of Albertville, for ordering them and their farm equipment off of Larson's father's property.
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