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Instructions for LCCC Investigator Initiated Chemotherapy Protocol Templates
- Choose your template depending on your study design, on whether your study includes a Phase I component, and whether it is a UNC Chapel Hill only (single center) or multi-center trial.
- The template documents open as word files; save as a word file once you start drafting your protocol. When opened as a word file, all the pages listed on the Table of Contents (TOC) revert to page 1. Place your cursor on the TOC, right click, and then click on "update field". Update "entire table", and the correct page numbers should appear.
- Please do not clear the formatting on your template.
- The Table of Contents (TOC) is hyperlinked. After selecting the TOC, if you hold the cursor just in front of a page number on the TOC and hit the control key and then left click on your mouse, your cursor will jump to that section in the document.
- All instructions in the template are highlighted in yellow. Please review these instructions and address as applicable for your protocol.
- If you select all instructions for a particular section and start typing, this should delete the instructions, and remove the highlighting. If it does not, select the text you want to remove highlighting from, click the arrow next to Highlight on the Formatting toolbar, and then click "None."
- Those sections not highlighted include standard boilerplate language that should remain in your draft.
- If a particular section is not relevant for your study, just remove it-your document should automatically re-number for you. Similarly, if additional sections are needed to clarify your study, insert as appropriate.
- Once you have completed your draft, select the Table of Contents (TOC), right click and then update your TOC.
- If you have any questions about the templates, please contact Jeanne Noe at 843-7130, email@example.com
I. Single Center Chemotherapy Phase I, Phase I/II, Phase II
II. Multi-Center Chemotherapy Phase I, Phase I/II, Phase II
III. Health Services Research Template

subset: commoncrawl


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HIV Prevention for Serodiscordant Couples
I. Definition of the Prevention Area
HIV-serodiscordant couples, in which one partner is HIV-positive and the other is HIV-negative, are now recognized as a priority for HIV prevention interventions.
II. Epidemiological Justification for the Prevention Area
Although there is considerable variation across countries, recent studies in sub-Saharan Africa with mature epidemics show that up to two-thirds of infected couples are discordant. These studies seek to assess the extent to which HIV transmission within marriages was spurred by high infection rates in sub-Saharan Africa due to heterosexual transmission. One analysis estimated that 55 to 92 percent of new, heterosexually acquired HIV infections among adults occurred within serodiscordant marital or cohabiting relationships. Additionally, among discordant couples, only the female partner is infected in 30 to 40 percent of cases, dispelling a common misperception that only men, not women, are the HIV-positive partner.
According to a research review, the following factors make it more likely that a person living with HIV will transmit the virus to his or her partner: the presence of other sexually transmitted infections, particularly genital ulcerative diseases; high viral load; failure to use condoms correctly and consistently; and specific sexual practices such as a high number of sexual partners and higher frequency of sexual contact. Concurrent sexual partnership may also contribute to risk. The risk of transmission is especially high during early infection, when it is estimated to be 26 times more infectious than during later stages of infection. This makes it especially important to identify HIV infection during the acute stage.
Prevention responses also need to take into account the progress of the epidemic. One hypothesis is that in early epidemics, most discordant couples arise due to HIV infection of one partner from a preexisting relationship, whereas in more mature epidemics, a greater proportion of discordant couples initiate relationships with a new partner who is already infected.
III. Core Programmatic Components
HIV prevention programs among discordant couples are traditionally based on three types of interventions: 1) couples HIV voluntary counseling and testing--via both community-based outreach and in antenatal clinics, 2) group-based workshops with serodiscordant couples, and 3) integrated antiretroviral therapy and HIV prevention programs. These programs often include risk reduction counseling, referrals to treatment, counseling on family planning, and an avenue to further care and support services.
Couples HIV counseling and testing is the cornerstone of many discordant couple interventions; it remains the only way to identify couples in which one partner is HIV-positive and one is HIV-negative. New and innovative methods are being developed to increase uptake of couples counseling and testing as many individuals and couples do not know their status. To increase HIV testing among couples, couples testing programs will likely require integration with broader HIV programs including care, treatment, and support services; mother-to-child-transmission programs; male circumcision; condom promotion; partner reduction; and other behavior change interventions.
Effective prevention programming is necessary for serodiscordant couples, targeted both to the couple and to the individuals. One study showed that the HIV-negative partner increased their number of outside sexual partners after learning the HIV-positive status of their partner. Campbell et al. confirms this result, showing that about 27 percent of seroconverters in serodiscordant couples in the study were infected by an outside partner.
New advances in the biomedical field have demonstrated success in reducing HIV transmission among discordant couples, namely pre-exposure prophylaxis and antiretroviral therapy as prevention. These prevention methods are still under development, and their real-life applicability is currently being reviewed, but they could prove to be valuable prevention methods in the future.
IV. Current Status of Implementation Experience
Programs in developing countries aimed at reducing transmission of HIV in discordant couples are too new to evaluate for effectiveness. To date, interventions have largely been conducted within structured research protocols, so it is still uncertain whether the efficacy of such interventions will work in real-life settings, and whether such interventions can be scaled up to achieve sufficient reach to reduce overall rates of HIV transmission.
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The secondary data analysis study explored how pregnancy in serodiscordant couples affected HIV-1 acquisition in women and HIV-1 transmission from women to men. Data from 3,321 African couples in seven countries who were enrolled in the Partners in Prevention HSV/HIV Transmission Study, a study that tested the effect of acyclovir herpes simplex virus type 2 suppressive therapy for the prevention of HIV transmission, was utilized. Multivariate Cox proportional hazard analysis was performed to control for any demographic, clinical, or behavioral factors. During the study period, 151 individuals seroconverted (with 61 infections occurring among women and 90 occurring among men) and there were a total of 823 pregnancies. Couples who became pregnant were younger and more likely to report unprotected sex during pregnancy. About 28 percent of women who HIV-1 seroconverted during the study were pregnant. The incidence of HIV-1 during pregnancy was 7.35 per 100 person-years compared to 3.01 per 100 person-years during nonpregnancy, but was not found to be statistically significant in multivariate analysis. About 21 percent of men who HIV-1 seroconverted during the study period did so while their partner was pregnant. The incidence of female-to-male HIV-1 transmission was 3.46 per 100 person-years during pregnancy compared to 1.58 per 100 person-years when the partner was not pregnant, and was statistically significant after multivariate analysis. In conclusion, there is an increased risk of HIV acquisition among HIV-negative women and increased risk of HIV transmission to men during pregnancy, which calls for more emphasis on risk reduction counseling, family planning, and early initiation of antiretroviral therapy during pregnancy among discordant couples.
This article reports expanded demographic and clinical information from the HIV Prevention Trials Network 052 trial, whose interim findings, released on April 28, revealed a 96 percent reduction in the risk of HIV transmission among participants with a CD4 count between 350 and 550 cells per cubic millimeter (cells/mm³) who received antiretroviral therapy (ART) immediately upon entering the trial. Over half of the participating serodiscordant couples (54 percent, or 954 couples) came from Africa, 531 couples from Asia, and 278 couples from the Americas; 50 percent of the infected partners were men. Enrollees were randomized to receive ART immediately upon testing positive or to delay therapy until their CD4 counts dropped below 250 cells/mm³ or they acquired an AIDS-related illness. Of the total of 39 HIV transmission events, 35 occurred among participants in the delayed arm (with 82 percent occurring among African couples). A total of 61 percent of the 28 "linked" events (in which HIV transmission was directly linked to the infected study partner) occurred among individuals whose partner had a CD4 count greater than 350 cells/mm³, and 64 percent of the HIV transmissions were from female to male partners. Individuals in the immediate treatment arm experienced a 41 percent lower risk of experiencing a clinical event, such as tuberculosis, compared to those in the delayed arm. According to the authors, the most likely mechanism in preventing HIV-1 transmission was sustained suppression of HIV-1 in genital secretions--the result of ART. The authors found that early initiation of ART has clinical benefits for both HIV-1-infected individuals and their uninfected partners, and therefore must be rolled out as a prevention strategy to reduce the spread of HIV-1 infection.
The observational cohort study examined the relationship between HIV-1 seroconvertion before and after antiretroviral therapy (ART). Discordant couples were indentified through the annual Rakai Community Cohort study and used data from 2004 to 2009 surveys. In 2004, all HIV-positive Rakai residents were offered free ART if their CD4 counts were at or below 250 cells/mL or were at stage IV disease as defined by the World Health Organization. HIV incidence and risk behaviors of the uninfected partners were retrospectively compared with when their partner started ART. During the 2004 to 2009 time period, 250 discordant couples were identified, of whom 32 met the criteria for initiation of ART. In 58 percent of the couples, the male was the HIV-positive index partner. It was found that before the initiation of ART, the transmission rate was 9.2/100 person-years (95 percent confidence interval, 6.59-12.36). There were no HIV-1 transmissions among the couples who started ART. There were no statistically significant differences between the two groups (ART versus non-ART). Consistent condom use with any partner increased from about 14 percent prior to ART compared to about 54 percent after ART and was statistically significant. Viral loads were found to be high. At 6 months, the majority (71.4 percent) had viral loads below 400 copies/mL. The reduced HIV-1 transmission levels among discordant couples most likely were due to the reduced viral loads of the HIV-positive partner.
The study explored the differences between HIV-negative couples verses HIV discordant couples, and HIV-positive concordant couples verses HIV discordant couples. Data was from the 2007 nationally representative Kenya AIDS Indicator Survey, which collected self-reported data on variables such as demographics, sexual behaviors, male circumcision, and pervious HIV test. Blood samples were also drawn to test for HIV antibodies, herpes simplex virus type 2 (HSV-2), syphilis, and CD4 counts for those who tested HIV positive. A total of 2,748 couples were in the sample and 9.6 percent were affected by HIV (3.8 percent HIV concordant; 5.8 percent HIV discordant). The woman partner was infected with HIV in about half (48.5 percent) of the couples. For HSV-2, both partners were positive in 30.4 percent of the couples and only one partner was positive in 20.7 percent of couples. Of the HIV-positive individuals who were married or cohabitating, less than half (42.8 percent) had a previous HIV test and only 16.4 percent correctly knew their status. A minority (14.9 percent) of HIV-positive individuals who were in a couple both correctly knew their status and disclosed to their partner. Factors associated with HIV discordance compared to HIV-uninfected concordance were younger age in women, increased number of lifetime partners in women, HSV-2 infection is one or both partners, and lack of male circumcision. Factors associated with HIV concordance compared to HIV discordance were HSV-2 infection in both partners and lack of male circumcision. In conclusion, more emphasis should be placed on prevention programs targeted towards married or cohabiting couples since they are a population at high risk of HIV transmission and acquisition.
The study linked the HIV-1 strains within HIV discordant couples when the uninfected partner seroconverted to determine if the infection could be epidemiologically connected to the infected partner. The data was from the Partners in Prevention HSV-2/HIV-1 Transmission Study that enrolled HIV serodiscordant couples from several African countries. A total of 3,408 discordant couples were enrolled in the study, and 155 seroconverted to HIV during the course of the trial identified through HIV-1 serology at site. A total of 151 were confirmed by a positive HIV-1 Western bolt test and included in the analysis. The majority (71.5 percent) of transmissions were linked to the infected partner, 26.5 percent were not linked to the infected partner, and 2 percent could not be determined. Seroconverters were most likely female, had a shorter average time to seroconversion than unlinked pairs (6 months versus 12 months after enrollment), and were identified within the first 3 months of the study visit compared to after 3 months. Reporting sexual activity with the infected partner was higher among those who had linked cases. Unlinked cases reported increased sexual activity with outside partners compared to linked cases, and these unlinked cases were more likely male. It was also found that the HIV-positive partner had higher baseline plasma HIV-1 RNA levels in linked cases versus unlinked cases. The results of the study underscore the necessity of HIV prevention interventions targeted toward serodiscordant couples, and messages should be uniquely tailored to gender and HIV-1 status characteristics.
Recent studies show that new HIV infections are from individuals in serodiscordant couples. Data from 10 Demographic Health Surveys and AIDS Indicator Studies were used in the analysis. Each is a population-based survey, which included biological samples to test for HIV-1 antibodies. A total of 1,107 serodiscordant couples were found in the 10 surveys, and half of the countries had less than 100 couples in its sample. It was found that serodiscordant couples shared similar characteristics to the general population. Serodiscordant couples were found in rural and urban areas, there was no male/female difference in who was the HIV-positive individual in the couple, most have never been tested for HIV and did not know their status, many individuals in serodiscordant couples had low comprehensive knowledge on how to prevent HIV transmission, and most did not use condoms. These trends were similar in the general population. Couples HIV testing and counseling needs to be strengthened to identify serodiscordant couples. Then, more targeted programming needs to be implemented to increase services and programs to promote positive health and reduce risk-taking behaviors. Lastly, policy recommendations and program implications are provided.
A systematic review of peer-reviewed and unpublished data as well as a meta-analysis on 14 Demographic Health Surveys was performed to determine the gender balance of the index partner in HIV serodiscordant couples. Only African countries were included in the review and analysis. A total of 19 journal articles and 5 conference abstracts were included in the review as well as unpublished data from two cohorts from a study with The AIDS Support Organization. In the analysis, it was found that about half (47 percent) of the index partners were female. When the female was the HIV-positive partner, they were more likely an urban resident, from a country of a higher latitude (i.e., East Africa), older, from a country with more gender equality, and from a country with a lower HIV prevalence compared to others in the model. Program targeting serodiscordant couples should give equal importance to both male and females in the couples.
The Kenyan study examined the acceptance of couple counseling at prevention of mother-to-child transmission (PMTCT) centers and to assess if couple counseling increased uptake of PMTCT services. The cohort study was conducted from 2001 to 2003 in Nairobi, Kenya, within prenatal clinics. Data on HIV prevalence, uptake of couples voluntary counseling and testing (VCT), acceptance to testing, nevirapine use, personnel costs, and costs of supplies were collected from clinics and from the 2,833 women enrolled. It was found that 15 percent of women were HIV-1 positive. Fourteen percent were counseled as couples, and women who received couple counseling were more likely to receive nevirapine compared to those were counseled individually. Couples VCT had a higher number of women accepting HIV testing compared to the standard option. Couples VCT also resulted in more infections averted and disability-adjusted life years (DALYs) saved compared to the standard option (91 versus 88 infections averted; 2,861 versus 27,772 DALYs saved). Couples VCT was cost-effective, especially in areas of higher HIV prevalence. Increasing men's involvement in prenatal care is essential to augment HIV testing and improve PMTCT service uptake among women.
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The review explores the various HIV prevention options within serodiscordant couples. Half to two-thirds of HIV-1- infected adults are in a couple with an uninfected partner; therefore, prevention interventions need to be targeted toward these relationships. The primary service is offering couples HIV testing and counseling (CHTC). Studies have shown that serodiscordant couples who participated in CHTC report increased condom use, uptake of family planning, and uptake of prevention to mother-to-child transmission (PMTCT) services. Antiretroviral therapy for the prevention of HIV is another method to reduce transmission to the uninfected partner, though efficacy is still being explored. Pre-exposure prophylaxis is a prevention option for the HIV-uninfected partner in a serodiscordant couple. The paper also details positive evidence on PMTCT, behavior change interventions, and male circumcision and its challenges. A combination of prevention interventions is necessary.
A prospective study was conducted to measure the sexual behaviors of HIV-negative individuals in serodiscordant couples. Data was from the Partners in Prevention HSV/HIV Transmission study that was carried out from 2004 to 2008 in seven African countries. The HIV-negative partners completed an interviewer-administered questionnaire on sexual behavior at enrollment and every quarter. Blood samples were also collected to genetically link the HIV subtypes of the HIV-positive partner to the newly infected partner. A total of 3,381 serodiscordant couples were enrolled in the study. Over the two years of follow-up, the number of outside partners among the uninfected individuals in the couple increased from 3.1 percent to 13.9 percent. Those who reported sex with their HIV-positive partner in the month prior to the questionnaire were less likely to have an outside partner. Uninfected partners reported less sexual activity with their infected partner during the two-year follow-up period (73.2 percent to 93.5 percent). There was also an increase of the uninfected partner reporting no sexual activity with the infected partner and an increase of sexual activity with an outside partner during the follow-up period. Condom use was more common among outside partners than with the HIV-positive partner. Of those who HIV seroconverted during the study and reported to have an outside partner, most (86 percent) had an HIV subtype that was distinct from their HIV-positive partner, which indicates that they did not acquire HIV from their primary relationship. Risk-reduction measures adopted by the HIV-negative partner should be taken into account when counseling serodiscordant couples.
A qualitative study was conducted to identify influences on adherence to pre-exposure prophylaxis (PrEP) from both the HIV-negative partner and -positive partner in serodiscordant couples. Participants who were enrolled in the Partners PrEP study and were from the Kabwohe Clinical Research Centre in rural Uganda were sampled for this study. Forty-five PrEP participants and fifteen of their partners were interviewed. Mean duration of the partnership was 9.8 years, and 80 percent of the couples had children. It was found that there was a dilemma between wanting to continue the relationship but fearing infection, loss of health, and early death when learning of their discordant status. PrEP offered many a means for hope and opportunity in being able to maintain the relationship while staying uninfected. In other couples, tension and anger still persisted after PrEP use, and adherence suffered. The results of the qualitative study suggest that the strength of the relationship has a direct effect on adherence. Participants also preferred to use PrEP over condoms as an HIV prevention method. It is important to understand why couples want to stay together in supporting PrEP adherence.
The paper describes a modeling study that tested various scenarios on the effectiveness of early initiation of pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) for prevention within HIV serodiscordant couples. The model used data from three sites in South Africa that participated in the Partners in Prevention HSV/HIV Transmission Study as well as results from the specific clinical trials on PrEP and ART for prevention. Three analyses were performed: 1) four different PrEP implementation strategies, 2) starting PrEP then discontinuing use when the infected partner begins ART compared to early ART but no PrEP, and 3) various models were tested to determine the optimal combination of PrEP and ART, and cost and efficiency were reviewed as well. It was found that PrEP use at all times, whether or not the infected partner was taking ART, was the most effective out of the four scenarios in reducing transmission. For the second analysis, it was found that both scenarios increased costs and reduced infections. For the third analysis, when PrEP and ART were available, it would be most effective for higher-risk couples to offer PrEP to the uninfected partner before the infected partner started ART. For lower-risk couples, early initiation of ART would be the most cost-effective. In conclusion, PrEP and ART could be reliable combination prevention strategies to reduce transmission and acquisition for serodiscordant couples.
The paper examined serodiscordant couple's knowledge, attitudes, and understanding of male circumcision, as they are a high-risk group for HIV transmission and acquisition. Couples were recruited at a research clinic in Kampala, Uganda, for this cross-sectional study. A standardized gender-specific questionnaire was administered to each partner separately, medical records were reviewed to know their HIV serostatus, and an examination was performed to determine if the male was circumcised. The final sample size in the study was 318 couples. The majority of men were not circumcised (67.2 percent). Both men and women had a high knowledge of the protective ability of male circumcision. The majority had heard a health information message stating the benefits of male circumcision to HIV-negative men. Over 90 percent of participants had a favorable attitude about male circumcision as an HIV prevention strategy. About half (53 percent) of uninfected males expressed interest in undergoing male circumcision, while the majority (88 percent) of their female partners wished that they undergo the procedure. Uninfected males were more interested in undergoing male circumcision if they had discussed the procedure with their female partners and were knowledgeable on the positive benefits of male circumcision, compared to those who did not discuss it with their partners and were not knowledgeable. The main motivators to get circumcised were to prevent sexually transmitted infections/HIV infection and hygiene benefits. Barriers included cost of the procedure, being absent from work, fear of complications, fear of pain, and religious sentiments. The findings will aid in developing messages to promote male circumcision in Uganda.
The review explores the efficacy of prevention programs for people infected with HIV in the developing world setting. The review also seeks to explore if interventions targeting both HIV-positive and -negative individuals have varying effectiveness. Eighteen articles met the criteria for inclusion. Most (15 studies) were conducted in Sub-Saharan Africa, were in clinical settings (14 studies), and were with heterosexual populations (12 studies). Nine studies targeted both HIV-positive and HIV-negative individuals and stratified the results by target population. These nine studies were within HIV counseling and testing interventions. Ten studies evaluated behavioral interventions targeted to HIV-positive individuals. Five studies were with serodiscordant couples. When comparing behavioral interventions targeting HIV-negative and -positive individuals, it was found that condom use statistically increased among positive individuals but was not statistically significant among negative individuals. Interventions targeting serodiscordant couples increased condom use significantly. There was also a modest positive affect on reducing multiple sexual partners in behavioral interventions targeted to HIV-positive adults as well as an increase in disclosing one's HIV-positive status. These results demonstrate the positive affect on behavioral outcomes from prevention interventions; therefore, prevention interventions should be expanded among HIV-positive individuals and serodiscordant couples.
The paper describes a successful intervention to increase uptake of family planning services among HIV-1-serodiscordant couples in Kenya. Study participants were from the Thika, Kenya, site within the Partners in Prevention HSV/HIV Transmission Study, and compared with three other Kenyan sites that did not have the supplemental family planning intervention. At the Thika study site, 213 serodiscordant couples were enrolled, and the majority (74.7 percent) of infected partners were female. Most women had one living child and were married to their study partner. A total of 1,216 couples were enrolled in the other three Kenyan sites and were similar to the Thika participants. It was found that noncondom contraceptive use increased among Thika female participants, both in infected and uninfected women. The injectable was the preferred contraceptive choice of women followed by the pill, surgical procedures, implants, and intrauterine devices. Noncondom contraceptive use did not statistically change in the other three sites. Reported condom use was high throughout the study at all sites. The incidence of pregnancy also reduced among study participants from the Thika study site and increased at the other sites. The increased utilization of contraceptives in this cohort indicates an unmet need that can be satisfied with successful comprehensive family planning interventions.
The paper describes a study among serodiscordant couples where the HIV-positive individual has to disclose their status to their partner, they have to decide together to participant in the intervention, and to test whether there are any changes in condom use among study participants. The study was conducted in one site each in India, Thailand, and Uganda. Forty-three couples were enrolled in the study, and forty couples completed all study requirements. The intervention consisted of four sessions that covered HIV, risk reduction strategies, and skill training on how to improve couple communications. Participants were interviewed at baseline and at one and three months after the intervention. All participants stated that they were satisfied with the intervention and that it helped them communicate with their partner about sex. High communication skills were also reported at the one- and three-month follow-up visits. Participants appreciated the HIV information that they received, appreciated the correct information and skills on how to use a condom, and reported to be less shy about discussing HIV topics after the intervention. The ability to refuse sex if their partner did not want to use a condom increased significantly from baseline to the three-month follow-up visit. Sexual activity also increased in the India cohort based on the resumption of sex or the increased comfort level in discussing sex. Reported condom use at all sites reached 100 percent after the intervention. The study demonstrates how an intervention targeting serodiscordant couples can be replicated in multiple settings with unique epidemics.
According to the authors of this cross-sectional study, nearly 40 percent of HIV-positive Kenyans in stable serodiscordant relationships (where the partner is HIV-negative) expressed reservations about initiating early antiretroviral therapy (ART) for the purpose of treatment as prevention, particularly about the potential side effects. The HIV-negative partners expressed a high willingness (nearly 90 percent) to use pre-exposure prophylaxis (PrEP) over the long term. The authors also report that control of the method was a factor in participants' decision making since, when given a hypothetical choice, HIV-negative partners chose PrEP and HIV-positive partners chose ART if it was medically necessary. The larger PrEP study found that HIV-positive partners indicated a higher level of willingness to initiate ART when they were experiencing lower CD4 counts or symptomatic diseases, or had had personal experience with ART use. Based on these results, the authors suggest that serodiscordant couples follow a dual HIV prevention strategy, with the HIV-negative partner using PrEP until the HIV-positive partner is willing and able to initiate ART. The authors also stress the importance of understanding couples' concerns and preferences about using ART for HIV prevention, before developing treatment as prevention strategies.
This study explored condom use and number of unprotected sexual acts among long-term HIV serodiscordant couples after HIV testing and counseling and one-month follow-up visits. Participants were from the Partners in Prevention HSV/HIV Transmission Study, a randomized, placebo-controlled trial to assess the impact of twice-daily acyclovir use on HIV-1 disease progression in HIV-1/HSV-2 co-infected persons. The 508 HIV-positive participants and their partners were followed for two years. Couples received risk reduction counseling and were provided with free condoms each month, and the HIV-negative partner was tested for HIV quarterly. Interviewer-administered questionnaires collected demographic and behavioral data at baseline and monthly visits. The study compared the sexual behavior of newly and previously tested persons at baseline as well as at months one, six, and twelve. It was found at baseline that for those who recently tested for HIV (less than seven days earlier), odds of reporting unprotected sex were greater than for those who had most recently been tested more than 30 days before; the odds became comparable at the one month mark and remained constant at the sixth and twelfth months. The odds of unprotected sex were lower at month one, six, and twelve compared to baseline. The authors conclude that HIV counseling and testing results in a reduction of sexual risk among HIV serodiscordant couples.
A qualitative study was conducted in Addis Ababa, Ethiopia, to better understand HIV serodiscordant couples' view of fertility and sexual relations in long-term relationships. Participants were selected from among those receiving services for antiretroviral therapy and prevention of mother-to-child transmission at three public hospitals. Thirty-six informants were recruited from two groups--individuals in serodiscordant relationships and health professionals who care for them. The study found the core category of the "struggle to maintain (the) relationship." After couples learned that one partner was HIV positive, they either separated or strove to maintain the relationship. Those who wanted to maintain the relationship experienced a period of transition to become comfortable with their new status. Challenges arose when one partner wanted a child or more children and the other did not, or when both wanted a child but feared transmitting the virus to the uninfected partner. Participants also noted: a change in their desire to have sex; sacrificing of self-interest for the benefit of their family; nondisclosure or selective disclosure of their status to family and friends; and increasing focus of attention on existing children. The authors conclude that in order for HIV serodiscordant couples to maintain their relationship they have to develop a variety of strategies.
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The technical brief provides an overview of the research on HIV prevention for serodiscordant couples including an introduction on the epidemiological significance in targeting this population and key prevention interventions. There are three broad categories of prevention interventions among discordant couples: couples HIV counseling and testing, group-based interventions, and a supportive environment. Several successful programs are highlighted through the document. The challenges and barriers to implementing prevention programs for serodiscordant couples are listed, and their solutions are discussed. These include how to involve the partners in the intervention, gender imbalances, increasing knowledge about what it means to be discordant, and guaranteeing that the quality of interventions is high. Clear messages are outlined such as stating that HIV discordance is common, couples can remain discordant for a long time, discordance does not necessarily mean the partner is unfaithful, no one is immune to HIV, the HIV-negative partner is at high risk of HIV, and effective risk reduction options do exist. Four common questions that are pertinent to implementation are asked and answered in the brief. Additional resources are provided.
PrEP clinical trials have been successful in two populations--men and transgender women who have sex with men (MSM-TG) and serodiscordant heterosexual couples. However, translating these results to real world settings is less known. WHO recommends that countries implement demonstration projects that will offer advice on key safety, effectiveness, adherence, and sustainability questions surrounding PrEP interventions. The guidance provides an overview of the research conducted to date and recommendations on PrEP for serodiscordant couples, MSM-TG, and other groups. The guidance lists nine key points to guide demonstration projects including assuring the HIV-negative status of participants, monitoring the safely of participants, supporting high levels of adherence, and developing transition mechanism for those who want/need to discontinue treatment. It is planned that WHO will review and revise its guidance in 2015.
Debate Three: Discordant Couples and HIV Transmission
The World Bank and the U.S. Agency for International Development. 2010.
The co-sponsored World Bank and U.S. Agency for International Development debate was centered around the statement: "Intracouple HIV transmission between couples in long term stable partnerships drive a majority of HIV transmission and should receive the majority of HIV prevention funding." Two experts argued for and two argued against the statement. The summary report can be found at the site as well as additional materials including the program, supplemental information, flyer for the debate, and links to various pages on the AIDSTAR-One Prevention Knowledge Base. Viewers can also watch the debate in four parts through the website.


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Stowe Mountain Lodge Blog
Stowe-ga to Begin at Stowe Mountain Lodge!
If you take a look around any ski lodge on a busy Saturday morning, adults and children alike are all preparing for a day on the hill: eating a healthy breakfast, putting on layers and layers of clothing, helmets, goggles, etc. It's a workout in itself!
Occasionally you may notice someone stretching, but not as often as you should! Stretching is always a good idea, since skiing and riding can be an extremely strenuous activity. Stretching can prepare the muscles by increasing their range of motion around a joint. It should be performed in a slow, controlled manner prior to activity to reduce your chance for injury.
"From the Kitchen" with Executive Chef, Josh Berry
It is said that every great chef has a great sandwich up his sleeve for times in need of comfort food, a great lunch addition or any casual get-together. Stowe Mountain Lodge's Executive Chef, Josh Berry has several! One of his favorites, the Croque Monsieur, is the perfect addition to an après ski meal or any time that calls for a hearty snack! And it just so happens that this delicious concoction includes the three ingredients from the purveyors that we featured this year in our "From the Kitchen" video series: maple syrup from Green Mountain Maple Sugar, Cabot Clothbound Cheddar Cheese from Jasper Hill Farms and fresh baked bread from Red Hen Bakery.
Cranberry Cured Atlantic Salmon
This would be a great hors d'oeuvres, or perfect for a first course for an autumn dinner. The salty salmon is foiled perfectly by the sweet, tangy lemon curd and additional cranberries. A crisp 2008 Matua vineyards, New Zealand Sauvignon Blanc will pair exceptionally well with this dish.


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March 6 2015 Latest news:
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Tablet round-ups
Report: Huawei and LG to build two Google Nexus devices this year
Amazon's 3D printing vans could slash delivery times
Sony teases the Xperia Z4 Tablet it already leaked
Sony Xperia M4 Aqua launching with Z4 Tablet next week
Sony to unveil Xperia Z4 tablet at MWC 2015
Google Inbox rolls out to iPad, Android tablets and more browsers
Google to bin YouTube ads for paying customers
Samsung's Galaxy Tab S2 to be thinner than iPad Air 2?
O2 starts selling cut-price refurbished tablets
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Thomas Jefferson Ornament |
Click on image to enlarge |
The portrait of Thomas Jefferson depicted on this ornament was inspired by Jean-Antoine Houdon's bust of Jefferson, which resides in a marble niche in the Great Hall of the Library of Congress' Jefferson Building. The inscription on the ornament is Jefferson's impassioned June 1815 quote to John Adams, "I cannot live without books." Price: $24.95 Availability: Ships in 2-3 business days Product #: 21404066 |
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EagleMan wrote:This Is the End: Absolutely hilarious. One of the best comedies in many years.
Sigment Kurosai wrote:When dealing with an adaptation, critics should (imho) take into account how closely the movie follows the events of the original plot when rating it.
EagleMan wrote:I saw the Hannibal TV show. All in all a pretty good show.
Randori wrote:How thoughtful of you.
Well, I'm pretty excited for Pacific Rim. It's like an episode of Power Rangers but more of a real-life Megazords vs. Monsters fight. Gonna be awesome!
EagleMan wrote:I have seen some reviews call it smart, or even high IQ. The problem some people seem to be having is a.) unfaithfulness to the source and b.) actually being a bit of a slow, even "boring" movie (which it's fair to expect it might've been more actiony given the trailers and being a summer blockbuster).
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Start learning with our library of video tutorials taught by experts. Get started
Communicate complex ideas quickly and thoroughly with data visualization. Turn information into artwork and intrigue your audience.
Learn how to build an infographic that makes complex information easy to understand and visually compelling.
The founders of Pop Chart Lab describe the design process for one of their poster-sized infographic prints, "The Nebula of NES Games."
Learn the basics of what goes into creating an infographic.
Presents a short series of CSS animation techniques, such as looping, playing, pausing, and more, and puts them together in a small project: an animated infographic.
Shows how to create an area bubble infographic, or graphic representation of data.
Shows how to depict complex relationships in an easy-to-understand infographic, or graphic representation of data.
Covers the first steps in creating infographics, graphic representations of data—organizing sample data and preparing a wireframe.
Shows how to create a custom interactive bar chart or other visual graphic with jQuery and Dreamweaver.
Shows how to create a custom interactive bar chart or other visual graphic with jQuery.
"lynda.com has made it possible and affordable to retool and get back to work after raising my kids. I can't imagine working without this resource now." —Maureen C.
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Peace in the Tijuana River Valley
Marty Graham 5:30 p.m., Feb. 26
Posted April 9, 2008
Barbarella Fokos noon, Feb. 26
Walter Mencken 10 a.m., Feb. 26
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Mentor Graphics Retains Goldman Sachs and Merrill Lynch To Advise On Unsolicited Offer From Cadence Design Systems
WILSONVILLE, Ore., June 30, 2008 -- Mentor Graphics Corporation (Nasdaq: MENT) today announced that its Board of Directors has retained Goldman Sachs and Merrill Lynch as financial advisors with respect to Cadence Design Systems, Inc.'s (Nasdaq: CDNS) unsolicited written proposal to acquire all outstanding shares of Mentor at a price of $16.00 per share. In addition, Latham & Watkins LLP is acting as legal advisor to Mentor Graphics.
About Mentor Graphics
Mentor Graphics Corporation (Nasdaq: MENT) is a world leader in electronic hardware and software design solutions, providing products, consulting services and award-winning support for the world's most successful electronics and semiconductor companies. Established in 1981, the company reported revenues over the last 12 months of over $850 million and employs approximately 4,200 people worldwide. Corporate headquarters are located at 8005 S.W. Boeckman Road, Wilsonville, Oregon 97070-7777. World Wide Web site: http://www.mentor.com/.
Mike Buckley, Sabrina Guttman or Ashley Zandy
Brunswick Group – San Francisco
Guy Potvin
Brunswick Group – New York


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Justin Heacock Interview
Justin Heacock Interview
Goddard Videos
Goddard Videos
Watch More Goddard Videos
The beloved Haybarn Theatre, which, as its name suggests, was originally a working hay barn on the Martin Family Farm, was erected in 1868 and moved to its current location on the Greatwood Campus... more
Haybarn Theatre
Published on Sept. 18, 2011 on WPTZ News Channel 5.
Stephan Ross, a 1959 graduate of Goddard College, returned to the school Sunday to receive an award and speak to students about his... more
Students & Alumni
Phyllis Katz de Mantalvo (BA RUP '67) called the Goddard Storyphone to tell us her memories of Goddard College in the late 1960s. "I remember the sheer beauty of it," she says, speaking of the... more
About Goddard
Goddard College's MFA in Interdisciplinary Arts program presents guest artist ... more
MFA in Interdisciplinary Arts
Danielle Abrams, Faculty, MFA in Interdisciplinary Arts Program. "I am delighted to be a returning faculty advisor to Goddard where I have taught, and learned, as a faculty member since 2005."
MFA in Interdisciplinary Arts


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Stryker Vest
The Women' s Field Armor Stryker™ vest features all of the same construction and CE certification standards as the men's version but has been retailored for a woman's fit. The back armor plate has been made slightly shorter by changing to a five or six plate arrangement. Additionally, the midriff and hook and loop adjustment straps have been rescaled for a proper fit. Of course the main function of the vests back protector, enhanced protection, remains intact as the women's version meets applicable CE certification standards for back protectors.
$130.00 Suggested Retail USD
- EN 1621-2/03/AC2006 CE Approved Stryker Back Armor
- d3o Breathable back insert, with custom molded ICON geometry
- Articulating injection molded back armor with air flow channels
- Injection molded chest plate with integrated air intakes
- Vented biofoam and airmesh chassis
- Hydradry moisture wicking liner
- Highly adjustable waist and shoulder straps
- Low-profile design fits under most jackets
- Women specific fit
Include your question or comments below.
We will reply as soon as possible.
Is there a way to customize the colors I'd want for my field armor vest?
There is no way to customize the colors of the vest from the factory.
I have this armor, I lost some of the back screws for it, where would I be able to order more?
The rivets for the Stryker vest are not replaceable
Hello, I am interested in buying a Stryker vest, but I do not see where in where I can buy one on this website. Do you have this option, or must I buy it in a dealer only?
ICON does not sell directly to the public, but we have a variety of online retailers that do. They can all be found here: http://www.rideicon.com/dealer-locator/


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Subject to availability. Valid for Price Band A tickets on 19 June. Must be used in one visit. Offer price already includes a per-ticket booking fee. Advance booking required. Cannot be combined with any other offer. No cash value or cash back. The regular value stated is based on the maximum combined cost of the items in this package at time of publication. Price Band A tickets usually cost £19.50 plus a £2.90-per-ticket fee. A one-off transaction fee of £2.85 applies.


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15 Radio Streams Click Here |
Brought to you by Mexico Lindo
Thursday, January 17, 2013
This info. just in from the Heflin Police Dept.
Temperatures are expected to drop below freezing tonight. Please drive safely and anticipate ice patches on the roadway. Expect extended response times from emergency services.
Cleburne County Schools will open at 10 AM tomorrow (Friday January 18, 2013), and The Cleburne County Courthouse will also open at 10 AM tomorrow due to anticipated hazardous road conditions.
Alabama Authorities Discover Fraudulent Tax Returns
Tips to Add Design Appeal to Your Home
Alabama investors strongly advised to consider cyber security
Alabama Sec of State's Website offers abundance of information
Keywords: Heflin,,Cleburne County Schools ,The Cleburne County Courthouse ,hazardous road conditions,freezing,
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Video Overview
Eric Pollard joins the outerwear team
Dakine is very pleased to welcome Eric Pollard to our outerwear program. Eric has been a part of the Dakine family for over a decade and brings an immense amount to our outerwear development. We look forward to years of progress and development with his influence.
2013 Dakine Technical Outerwear Video Preview
Featuring Dakine's 2013 Technical Outerwear Team Riders Chris Benchetler, Shayne Pospisil, Sami Luhtanen and Sam Cohen rockin' the new gear!


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Judges' Pick
To build happiness requires a common understanding of that which is essential to life.
The design of this plate tells a positive story of water use, and is a storytelling tool to educate children on the principles of the water cycle: flow, evaporation and precipitation.
Clean water is a necessity for all life on earth. The story on the plate is a reminder to those of us in the developed world that water comes from, and returns to, nature; and that people, plants and animals around the world all depend upon clean water to live and prosper.
Children can immerse themselves in this illustrative story of water as it surrounds their food, and imagine a world where water use is in perfect balance.
The text around the edge of the plate reads "Water. For Life."


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Quantico (Prince William County, VA) Change Neighborhood
- Overview
- Schools
- Homes Sold (1)
- Homes for Sale (2) selected
Quick Facts
Local DC MD VA Area News
Average US rate on 30-year mortgage drops to 3.75 percent
Average long-term mortgage rates have fallen for the first time in four weeks and remain near historic lows reached in May 2013.
Mortgage rates tick down this week
The drop is spurred by weak fourth-quarter economic data.
Former Roanoke woman sentenced for mortgage fraud
A former Roanoke woman has been sentenced to eight years in prison for operating a Smith Mountain Lake mortgage fraud scheme.
Average US rate on 30-year mortgage rises to 3.80 percent
Average long-term U.S. mortgage rates have edged up for a third straight week while remaining near their historically low levels reached in May 2013.
Morgan Stanley to pay $2.6B to settle charges over mortgages
Bank agrees to settle with the U.S. government over its role in the mortgage bubble and subsequent financial crisis.
New Palestinian city has condos, a mall and a sports club — but no water
The opening of the billion-dollar enclave of Rawabi is stalled because Israel won't grant water access.
Renting vs. buying — crunching the numbers on two D.C. condos
Study the pros and cons of each option to determine which is right for you.
US home sales drop 4.9 pct. in January; job growth and low mortgage rates fail to spur buying
US home sales drop 4.9 pct. in January; job growth and low mortgage rates fail to spur buying.
Study shows consumers spend too little time mortgage shopping
Most buyers apply to only one lender.
Halfway house in D.C.'s Shaw to go condo
Nine luxury units would deliver in 2016.
Real Estate Matters | Board expenditure smells fishy to condo owner
Association documents could spell out whether actions were foul play.
Town Square | Construction to begin on condos and rentals in Arlington
Also free event seeks to equip first-time home buyers.
Old laundry is freshened up with 6 new condos
Hill East building has six units, including two penthouses, each with a roof deck with sweeping city views.
Mortgage rates rise on U.S. job growth
Borrowers will pay an average of 3.69 percent this week, compared with 3.59 percent last week.
What you need to know before you buy into a condo association
Ask for the board's meeting minutes to help determine whether it is financially stable.
What you should know before you take out a reverse mortgage
Before taking out the loan, you should be sure to check the risks associated with one.
Town Square | Sales begin at new luxury condo in Bethesda
Also new townhouses available in Anne Arundel County.
Scientists are using underwater condos to learn what actually lives in the ocean
Scientists are using "underwater condos" to study the vast number of marine species that have never even been named.
Is HUD lax on ethical and legal violations? Its inspector general thinks so
The IG said in testimony obtained by The Washington Post that senior HUD officials have faced minor consequences for violating ethics rules and the law.
S&P settles suits over crisis-era mortgage ratings
A roundup of business news from around the world.


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12 Takes on Hamburgers
Mmm, hamburgers! If you're a fan of burgers you're going to enjoy every single one of these original takes on an all-American classic.
Check where to buy amazing hamburgers in this collection of 25 best burgers in the U.S., and if you're not eating meat these days, try out one of these veggie burger ideas.
Bistro Sliders with Pickled Onions
These grilled mini burgers are just right for big or small appetites. Topped with pickled onions and they become even more irresistible!
Classic Hamburger
Slow-cooked onions add moisture and flavor to these lean beef burgers. A quick blend of mayonnaise, ketchup, relish, and vinegar makes a perfect tangy, sweet, and creamy "special sauce" for this burger. We love the dill relish here, but use sweet relish if you prefer it. Serve with sweet potato fries.
Recipe: Classic Hamburger
Beef Burgers
Meaty all-American burgers are best made with grass-fed beef, which has a sweeter flavor and tender texture. If you don't own a grinder, have the butcher grind the meat on a coarse setting.
Recipe: Beef Burgers
Beef Burgers with Peanut-Chipotle Barbecue Sauce
Bobby Flay makes this extremely good barbecue sauce by spiking tomato puree with two forms of smoky chile ancho chile powder and chipotle in adobo sauce then adding peanut butter for sweetness. The sauce takes some time to prepare, but by doubling the recipe, it can be made in one large batch and kept in the refrigerator for up to two months.
Fajita Burgers
This spicy burger is served on an oblong roll, slathered with a spicy chipotle mayonnaise, and topped with roasted Anaheim peppers and a delicious slaw.
Recipe: Fajita Burgers
Blueberry-Beef Burgers
Whatever the season, burgers remain Americas favorite sandwich. When it is too cold to grill outdoors, broil the patties or use an indoor grill. In addition to the standard fixins' you can make your burgers more nutritious by adding dark greens, such as watercress or spinach.
Recipe: Blueberry-Beef Burgers
Sicilian Burgers
Recipe: Sicilian Burgers
Reprinted with permission of Hearst Communications, Inc.
Tex-Mex Chicken Burgers
Recipe: Tex-Mex Chicken Burgers
Reprinted with permission of Hearst Communications, Inc.
All-American BBQ Sliders
Recipe: All-American BBQ Sliders
Reprinted with permission of Hearst Communications, Inc.
Crispy Shrimp Po' Boy Burgers
Recipe: Crispy Shrimp Po' Boy Burgers
Reprinted with permission of Hearst Communications, Inc.
Meatloaf Melts
Recipe: Meatloaf Melts
Reprinted with permission of Hearst Communications, Inc.
Barcelona Burger
Recipe: Barcelona Burgers
Reprinted with permission of Hearst Communications, Inc.


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The Hitchhiker's Guide to Multi-Patterning
Video viewing problems? Contact Us.
Beginning at 20nm, the challenges of lithographic imaging require the use of double patterning. Does this mean designers will have to do twice as much work? What about those pesky cycle design rule errors? How will we be able to keep it all straight? And just what are EDA vendors and foundries doing to make the designer's life bearable?
The best place to get some straight answers is from someone who has already done it successfully. Come to this "talk show" format session to hear experts describe their multi-patterning trials and tribulations, and zero in on the critical factors that determine a successful outcome.
- Moderator: Ed Sperling, Editor-In-Chief, System Level Design
- Michael White, Director of Product Marketing Calibre PV, Mentor GraphicsRob Aiken, R&D Fellow, ARM
- Jean-Pierre Geronimi, Special Project Director in Central CAD and Design Solutions, STMicroelectronics
- Kuang-Kuo Lin, Director, Foundry Design Enablement, Samsung
- Lars Liebmann, Distinguished Engineer, IBM
- Luigi Capodieci, Director DFM/CAD and R&D Fellow, GLOBALFOUNDRIES
Design Areas: IC Design |


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Forum Post of the Day: What type of music do Azerothians make?
Acerba of Cenarion Circle started a pretty fun discussion the other day on her server boards: What type of music would typify various races and cultures of Azeroth? Sure, we all have our soundtracks for when we get tired of the in-game music, and the in-game music itself often has various themes that show again and again music to represent various concepts, but thinking about what music your character would listen to or what sounds you might here around a bonfire at Razor Hill (Well, besides L70ETC) or in a fine mansion in Silvermoon City is a really fun exercise. I'm one who often creates soundtracks for my PnP and MMORPG characters alike in order to understand this, so I find it a useful exercise for us roleplayers, as well.
Filed under: Analysis / Opinion, Lore, RP, Forums


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USB Subsystem
Today's complex IC designs feature more gates, tighter constraints, and shorter design cycles -- which increases the need for designers to implement a fully integrated subsystem IP. A type of subsystem that's silicon proven multiple times over. The goal of Mentor's IP Division is to offer exactly that -- a complete IP subsystem available in the standards-based connectivity space.
Mentor is proud to offer the industry's first ever, fully integrated, single-vendor USB Subsystem IP. The Mentor subsystem includes a USB-IF Logo compliant Multi-Mode USB controller (MUSBMHDRC) that supports USB 2.0 Embedded Host, Dual-role, On-the-Go (OTG), and device functionality. Also included as part of the USB IP subsystem is a USB 2.0 Hi-Speed PHY (MUSBHPHY), and has two software options for different design requirements:
- A micro-software component optimized for tiny footprint embedded applications (MUSB-MicroSW)
- A more fully featured Nucleus USB software option based on the Nucleus RTOS.
All the components of the Mentor USB Subsystem IP are silicon verified and USB-IF certified to deliver a high quality, low-risk solution for customers who use complex USB SoC designs.


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Have you ever noticed someone whose chest sinks inward in the front, kind of like a funnel? The first time I ever noticed this bony malformation was when I was in high school, and a friend of mine on the soccer team had one. It was called "pectus excavatum," he told me.
In my thoracic surgery training, I was often called upon to evaluate patients with this chest wall abnormality. As a result, I began to delve deeper into some of the issues that may affect people with this type of defect.
Pectus excavatum is the most common chest wall deformity and results from abnormal development of the sternum and its attachments. Most patients are self conscious about the defect and usually focus on its appearance but because this is usually present for much of a person's life, symptoms associated with it may not be totally obvious. Individuals affected generally get used to how they feel and try to overcome any limitations to the best of their abilities without even knowing that's what they are doing. Most patients describe some chest discomfort, shortness of breath when exerting themselves, lack of endurance, or feeling embarrassed in social situations when their shirt is off. It is not uncommon to hear patients say that they have trouble keeping up with their friends during activities, or that they avoid any activities that would require them to take off their shirt in public-such as going to a pool.
Most physicians aren't even aware that there is an effective treatment for pectus excavatum...


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quote:Yall should check out the newest trailer if you havent seen it. I just checked it out today.
quote:But hurt locker was amazing... If this is in the same ball park I will be pleased
quote:Sold as a gritty realistic take on the war, but was absurdly unrealistic
quote:my cousin who just got back from Iraq says the Exact opposite. he said Hurt locker was Exactly! like his second tour.... but nothing like his first
quote:Yes I'm sure he went with a 3-man eod team all over Iraq without a convoy, except when he left the wire alone. FWIW I watched it on the way back from Afghanistan.
quote:what text is this movie based on?
quote:The Hurt Locker really disappointed me. After we got done watching it I seriously wondered if we had watched the wrong movie. The critics raved about it and I couldn't help coming away very underwhelmed.
quote:The Hurt Locker really disappointed me


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Showing 1-10 of 10 items found in Places to Stay
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Innstead Bed and Breakfast
Early 20th century farm house located within walking distance to historic McCoy Library with one of the oldest genealogy collections in the midwest.
CITY: McLeansboro
Campbell Illinois Whitetails
Guests are welcomed into the comfortable rustic atmosphere of the hunting lodge. It has the accommodation for 9 with all the amenities of home.
CITY: Carmi
Glass Door Inn
A newly constructed bed & breakfast nestled in a serene rural setting. Private bath, outdoor spa, and porches. Fishing in samll lake and outdoor enjoyment.
CITY: Fairfield
Grayville Super 8
This recently opened facility presents an excellent accommodation for the traveler.
CITY: Grayville
Fairfield Uptown Motel
Large clean rooms with color cable television, free local calls and low room rates.
CITY: Fairfield
Briarwood Inn of Fairfield
FREE Continental Breakfast. FREE Hi-Speed Wireless Internet, Cable TV (105 Channels) with HBO, Iron & Ironing Board, Hair Dryer, In Most Rooms: Microwave & Refrigerator. Outdoor Pool
CITY: Fairfield
Briarwood Inn of Fairfield
Clean, reasonable rates, restaurant nearby, fitness center nearby. Close to town activities.
CITY: Fairfield
Budget Inn
Recently remodeled, clean, comfortable rooms at economical rates. Low: daily, weekly & monthly, rates available. Cable TV, non-smoking rooms available, restaurant on premises. For reservations call .
CITY: Fairfield
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Wipe Clean Book- United States of America
No longer available
- Overview
Filled with dozens of activities and puzzles, this colorfully illustrated workbook teaches kids about the states and capitals while letting them practice their writing, counting and memory skills. The wipe-clean feature provides a fun and eco-friendly alternative to traditional workbooks.
- 13" wide x 10" high
- 42 pages.
- Spiral bound.
- Practical exercises that develop problem solving and fine motor skills.
- Wipe-clean book means that exercises can be practiced again and again.
- Includes wipe-clean pen.
- Ages 4 and up.
- Dimensions & Care
- Wipe clean with a cloth.
- Shipping Info
- Please allow 5-7 business days for delivery. Delivery estimate includes monogrammed and gift-wrapped items.


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Franklin County CCAP launched as a pilot program in fall 2011. In November, the Educational Foundation announced the awarding of a $50,000 grant from the Virginia Tobacco Commission to support Franklin County CCAP. Read the story in The Roanoke Times.
Scott Bradford graduated from Virginia Western in 2010 thanks to his participation in the Community College Access Program supporting Salem. Read his amazing story as told by The Roanoke Times, "Program Made Tuition Possible."


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Green Snowman Classic Fair Isle Stocking
No longer available
- Overview
Like the Scottish sweaters that inspired its design, our stocking is knit from thick wool-blend yarns and features three jolly snowmen holding hands. Amply sized, it won't limit Santa's generosity, and a personalized cuff gives family members their own special sense of anticipation.
- 7" top width x 11" sock length x 27" long
- Sewn of a wool/acrylic blend and lined with pure cotton.
- Sold individually.
- Imported.
- Dimensions & Care
- Spot clean with a damp white cloth.
- Blot to remove excess water.
- Air dry.
- Shipping Info
- Please allow 5-7 business days for delivery. Delivery estimate includes monogrammed and gift-wrapped items.
International Customers: Items on this page are not eligible for Free Shipping. Please view our general guidelines for more information.
Also in this Collection
Classic Fair Isle Stocking Collection
reg. price $34.50 sale $19.99
- Personalization


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quote:"I do have an interest in playing for the USMNT again, if given the opportunity, I would"
quote:"Soccer is not a big part of me…I feel like I have so much more to give post soccer…that's how I want to be remembered"
quote:"I'm leaving tonight and going to Cambodia for 10 days"
quote:Yes, I'd prefer to have him on the team, as he's still our biggest(?) difference maker.
quote:Especially with our wing play lacking, he is needed sooner rather than later.
quote:He's given 10-12 years pretty much non-stop to the growth of US Soccer and MLS and that often goes under appreciated by both fans and media. He's been the bell cow and the poster boy for soccer here for a decade. If he's tired of it, he's tired of it.
quote:What's sad is that our two most dynamic wings are Cakes and run DMB
quote:"Soccer is not a big part of me
quote:If soccer isn't a big part of him he doesn't need to be part of te usmnt picture. I appreciate all he's done for the program but if you aren't in 100% you aren't in the right frame of mind to contribute to the team. What the shite is he doing in Cambodia anyway?
quote:It's more than just swinging in crosses. If you play wide you stretch out the defense and create more space for passes and runs
quote:Soccer is not a big part of me
quote:Are there any notable teams who have success without wide play? TIA
quote:You will see the tiki-taka in the MF from the likes of Spain and Barcelona where they make quick controlled passes in tight spaces. I think it's Ian Darke that calls it "football in a phonebooth". We dont have near the skill to do that though (not many do). And even then, those teams will still have width to make it easier to do that.


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Delicate Organza Trim Cami: An upgraded wardrobe staple! This comfortable jersey knit camisole has a touch of pretty sheer organza at the neckline. Scoop it up in every color!
Buy 2 or more for just $13.99 each!
(Buy-2 pricing does not apply to markdown colors.)
Read what customers are saying about this product:
Rating: 4.00 out of 3 votes cast
Nice Cami
I really like the camis as they are plain with no built in bra and lots of color options. Over time they do seem to shrink in the wash (cold water only, hang to dry), but I guess that happens with something of this type. They are comfy and great for layering. Would definitely purchase again.
Update to Previous Review
Hand washed both tops and they did not shrink. Would need a touch-up with a light iron or steaming but I don't like to iron and if you wear the top under something or as is with something over your shoulders you should be OK. The fabric is of good quality. I don't see the need to size up but I wouldn't throw these in the dryer. Will be ordering other colors in the same size. I am a medium to large but ordered the large. As I said, it just fits so if you want a looser feel, size up.
Daqyton, Ohio
Not Stretchy Enough
Lovely colors and well made. Fabric is of good quality. However, seems to run a tad small for size and perhaps if it had a bit more "give" or spandex, that would help. Next time I might order a size up.
Dayton, Ohio
Click here to read all of this product's reviews


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quote:I can't wait to see what this Christmas brings since he will have had a year to work on it
quote:You also had time to see tin tin I see. Your commitment to this thread is disappointing.
quote:I'm sick today, so I'll let this be my pet project.
quote:I watched 40 minutes of it today and have 7 pages worth of notes so far. I think I'll get about 10 pages and then edit it from there, since the family dynamics are so much more interesting than the booby traps and the burglar, and most of that is heavily concentrated in the first half.


text:
I am Jackie a Ferris State University grad. I spent my time at Ferris running on the varsity cross country and track team, Even though I am out of college I still am a crazy runner girl. I have done 5 marathons, and plan to do many more!
I began my career in broadcast when I was 24 and interned at Free Beer and Hot Wings in the Morning. That is where I got the incredibly accurate nick name of "Jackie Man Voice" or "JMV." From there I worked weekends on GRD and Channel 957 for a while until I was moved up to nights. I hosted the nightly Rocktagon for 2 years before I was moved again to where I am today, midday's (10-3 M-F)
I like to read more than anyone should, I am a musical theatre nut, I cosplay, dabble in pageants, and have a geek side a mile long. I am very active and I have a rare ability to go out and be crazy, and still get up hung over as all get up and go for my run... My favorite band ever is Shinedown I love them!
Catch me stumbling around Grand Rapids at our many GRD concerts and events. Of course you can also hear me Monday through Friday, 10AM to 3PM on GRD!


text:
Kevin Fox, MD
Ultima Vez Modificado: 24 de marzo del 2002
Dear OncoLink "Ask The Experts,"
Does breast cancer run along some continuum from estrogen-receptor positive to estrogen-receptor negative tumors? Are ER+ tumors a different disease than ER- tumors? I have been diagnosed with an ER- breast cancer and I am confused as to whether I am at increased risk of recurrence and general guidelines for prevention of recurrence.
Kevin Fox, MD, Assistant Director, Clinical Affairs and Associate Professor of Hematology/Oncology at the Abramson Cancer Center of the University of Pennsylvania, responds:
No breast cancer is purely ER positive or ER negative. Patients can assume that all breast cancers contain some ER+ and ER- cells, and that there is a continuum. The fact is, that tumors that are ER- have a higher recurrence rate than those that are ER+. If you have an ER- cancer: strategies to increase or decrease estrogen levels will have no bearing on your recurrence risk. You need not take special dietary steps to change your recurrence risk.
Feb 25, 2010 - The nonsteroidal selective estrogen-receptor modulator lasofoxifene may reduce the risk of fractures, stroke, estrogen receptor-positive breast cancer, and coronary heart disease in postmenopausal women with osteoporosis. However, the drug significantly increases the risk of venous thromboembolic events, according to a study in the Feb. 25 issue of the New England Journal of Medicine.


text: A money-saving alternative for dogs that do not need maximum joint support. Basic Kit contains Basic Joint Care, a foundational joint product with the key ingredients glucosamine HCL (hydrochloride) and chondroitin plus antioxidants to support the body's normal defenses. Basic Kit also contains Premium Plus Omega-3 Gel Caps to help maintain your pet's overall health plus Joint Guard Bites, with perna mussel and MSM, a tasty square that works in conjunction with the other two products. For dogs. Kit includes: 100 ct Premium Plus® Omega-3 Gel Caps, 100 ct Basic Joint Care, and 1 lb of 300 mg Joint Guard® Bites. May be used with NSAIDS, such as Rimadyl and Deramaxx. Please click on "More Information" for further details. Sorry, this item cannot be shipped to New Mexico. We apologize for any inconvenience. | ||||||


text:
Top 20 most valuable soccer teams
POSTED: 11:08 AM CDT May 13, 2014
No matter whether you're a Real Madrid or a Manchester United fan, take a look at which international soccer teams top Forbes' list of the world's 20 most valuable soccer teams.
The views expressed are not those of this company or its affiliated companies. Please note by clicking on "Post" you acknowledge that you have read the Terms Of Service and the comment you are posting is in compliance with such terms.


text:
John Han-Chih Chang, MD and Kenneth Blank, MD
Last Modified: November 1, 2001
Dear OncoLink "Ask the Experts,"
Will you please tell me what are the signs and symptoms of testicular cancer? I know a lump might be one sign, but what else could there be?
Kenneth Blank, MD, Editorial Assistant for Oncolink, respond:
Dear OncoLink Reader:
Thank you for your question.
You are correct. A lump on the testis is a sign of testicular cancer and is the most common presenting sign. However, not all testicular lumps are cancerous. Other signs and symptoms include:
If you feel a lump in your testis, or are concerned about any of the above symptoms, please consult your local urologist for a complete history and physical examination.
May 20, 2014 - According to two new studies, testicular self-examination is cost-effective and non-Caucasians with testicular cancer have worse outcomes. These findings were presented at the annual meeting of the American Urological Association, held from May 16 to 21 in Orlando, Fla.


text:
Thanks to I EAT BABIES for the thread that inspired this Comedy Goldmine.
Abyssal Squid
One roommate's art-fueled movement goes terribly wrong.
Emma Stone was the most paranoid person I had ever met. In private she wore a full suit of medieval armor at all times, visor down.
Reading is good, in general, but sometimes it's just another way to put insane porn into your body.
How to Enjoy this Article: 1) CLICK on the link 2) READ the intro (optional) 3)LAUGH at the artwork!
The Comedy Goldmine examines the funniest and most creative threads from the Something Awful Forums. Although the Comedy Goldmine has changed authors many times over the years, its focus on the Something Awful Forums is still the same. Includes hilarious Photoshops, amusing work stories, parodies, and other types of oddball humor.
Copyright ©2015 Rich "Lowtax" Kyanka & Something Awful LLC.


text:
Providing support for Westminster's athletic programs is the Towering Titan Organization (TTO), formed in 1976 around a core of devoted, loyal and intensely interested alumni, parents and friends. The organization purposes itself to help maintain, improve and endow Westminster College's athletic programs.
Over $3.5 million in gifts have been contributed to the Towering Titan Fund since its inception. The annual income is distributed in this manner: 90 percent of all donations go directly to the sport(s) chosen (donations can be designated to a specific sport for men or women); 5 percent of all donations go to the TTO Endowment Fund or the All-Titan Endowment Fund; and the remaining 5 percent of all donations goes to a general TTO fund and is used for operation and promotion of the fund. All 20 varsity sports for men and women benefit from the fund.
A minimum gift of $30 qualifies a donor for membership. Members receive issues of the Towering Titan Newsletter and invitations to social events, such as golf outings, and to recognition dinners and ceremonies that are scheduled periodically.
Qualifying gifts are also recognized through membership in Westminster's Giving Clubs. For more information or to join the Towering Titans, contact Westminster Director of Athletics Jim Dafler at (724) 946-7313 or by email.
2013-14 Towering Titan Organization (TTO) Executive Committee
Jack Marshall '67
Vice President:
Richard Mills '76
Henry Klinar '01
Committee Members:
Brenda Rodgers Briggs '86
Jodi Chmielewski '98
Joe Fusco '60
David Gooch '75
Janie Cebula Hale '97
Bill Hazen '65
Peter Horne '76
Nanci Kleese Hosick '95
Bob Latta
Lou Perrotta '94
Robert Power Jr. '70
Rick Reiber '74
David Richards '84
Support the Towering Titan Fund
Make your gift using our secure online giving form. Please make sure to designate your gift to the Towering Titan Organization or a specific sports team.


text: How To Find Cheap Airfare. By Mike Barus Air travel to Bed and Breakfast in San Antonio is no longer considered a luxury only available for the wealthy and is now almost essential to our way of life. Instead of driving hundreds of miles to visit friends and family, attend a business meeting, or enjoy a vacation hotspot, a flight can whittle your travel time to a couple of hours instead of a couple of days.


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Drug Notes
UPMC Patient Education Materials
Calculators and Assessment Tools
Anatomy Navigator
Conditions Navigator
A duplex ultrasound is a test to see how blood moves through your arteries and veins.
Related topics include:
Vascular ultrasound; Peripheral vascular ultrasound
A duplex ultrasound combines traditional ultrasound with Doppler ultrasound .
There are different types of duplex ultrasound exams. Some include:
You may need to wear a medical gown. You will lie down on a table, and the ultrasound technician will spread a gel over the area being tested. The gel helps the sound waves get into your tissues.
A wand, called a transducer, is moved over the area being tested. This wand sends out the sound waves. A computer measures how the sound waves reflect back, and changes the sound waves into pictures. The Doppler creates a "swishing" sound, which is the sound of your blood moving through the arteries and veins.
You need to stay still during the exam. You may be asked to lie in different body positions, or to take a deep breath and hold it.
Sometimes during a duplex ultrasound of the legs , the health care provider may calculate an ankle-brachial (ABI) index. You will need to wear blood pressure cuffs on your arms and legs for this test.
The ABI number is obtained by dividing the blood pressure in the ankle by the blood pressure in the arm. A value of 0.9 or greater is normal.
Usually, there is no preparation for a duplex ultrasound.
If you are having an ultrasound of your stomach area, you may be asked not to eat or drink after midnight. Tell the person doing the ultrasound exam if you are taking any medicines, such as blood thinners. These might affect the results of the test.
You may feel some pressure as the wand is moved over the body, but there is no discomfort most of the time.
A duplex ultrasound can show how blood flows to many parts of the body. It can also tell the width of a blood vessel and reveal any blockages. Duplex ultrasound is a less invasive option than arteriography and venography .
A duplex ultrasound can help diagnose the following conditions:
A renal duplex ultrasound can also be used after transplant surgery to see how well a new kidney is working.
A normal result is normal blood flow through the veins and arteries. There is normal blood pressure and no sign of a narrowing or blockage of a blood vessel.
An abnormal result depends on the specific area being examined. An abnormal result may be due to a blood clot or plaque buildup in a blood vessel.
There are no risks.
Cigarette smoking may change the results of an ultrasound of the arms and legs, because nicotine can cause the arteries to shrink (constrict).
Deane CR, Goss DE. Peripheral arteries and veins. In: Allan PL, Baxter GM, Weston MJ, eds. Allan & Baxter: Clinical Ultrasound. 3rd ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2011:chap 63.
Zivin JA. Approach to cerebrovascular diseases. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 413.
Deepak Sudheendra, MD, Assistant Professor of Interventional Radiology & Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.
UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, gender identity, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.
Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.
For UPMC Mercy Patients: As a Catholic hospital, UPMC Mercy abides by the Ethical and Religious Directives for Catholic Health Care Services, as determined by the United States Conference of Catholic Bishops. As such, UPMC Mercy neither endorses nor provides medical practices and/or procedures that contradict the moral teachings of the Roman Catholic Church.
© UPMC Pittsburgh, PA, USA UPMC.com


text:
0 Products found for this category
Sat Nav & Audio at Halfords
Satellite navigations and good audio system are must buy's for your car especially if you hate being stuck in traffic jam's or getting lost. A sat nav will ensure you don't get lost but if do at least you can listen to decent music, which will make the long journey bearable.
Satellite navigations come in a variety of different sizes with a number of funky functions. Before buying a TomTom sat nav consider where you are going to use it as you get the choice of UK, ROI and Europe. Other features to consider are whether it has the traffic function so it re-routes when there is a traffic jam ahead or the speed camera function.
Getting a new audio system like a dab radio means you can wave goodbye to crackly radio for good. As well as having the option to listen to any radio station you like wherever you are in UK, without going through the hassle of constantly re-tuning.
We also offer a wide selection of car speakers and subwoofers so you can enjoy high quality sound wherever you are. Our equipment is easy to fit so you can be raring to go in no time. Our helpful store staffs are able to fit your new sat nav or audio system for a small charge, which means you can get back on the road in no time.


text:
Drug Notes
UPMC Patient Education Materials
Calculators and Assessment Tools
Anatomy Navigator
Conditions Navigator
Chorionic villus sampling (CVS) is a test done on some pregnant women.
The test is done to screen your baby for genetic problems.
CVS can be done through the cervix (transcervical) or through your belly (transabdominal). Miscarriage rates are slightly higher when the test is done through the cervix.
The transcervical procedure is performed by inserting a thin plastic tube through the vagina and cervix to reach the placenta. The provider uses ultrasound images to help guide the tube into the best area and then removes a small sample of chorionic villus tissue.
The transabdominal procedure is performed by inserting a needle through the abdomen and uterus and into the placenta. Ultrasound is used to help guide the needle, and a small amount of tissue is drawn into the syringe. The sample is placed in a dish and evaluated in a laboratory. Test results take about 2 weeks.
Your health care provider will explain the procedure, its risks, and alternative procedures such as amniocentesis.
You will be asked to sign a consent form before this procedure, and you may be asked to wear a hospital gown.
The morning of the procedure, you may be asked to drink fluids and refrain from urinating. Doing so fills your bladder, which helps the doctor see where to best guide the needle.
Tell your health care provider if you are allergic to iodine or shellfish, or if you have any other allergies.
The ultrasound doesn't hurt. A clear, water-based conducting gel is applied to your skin to help with the transmission of the sound waves. A hand-held probe called a transducer is then moved over the area. In addition, your health care provider may apply pressure on your abdomen to find the position of your uterus.
The cleansing solution will feel cold at first and may irritate your skin if not washed off after the procedure.
Some women say the vaginal approach feels like a Pap smear with some discomfort and a feeling of pressure. There may be a small amount of vaginal bleeding following the procedure.
An obstetrician can perform this procedure in about 5 minutes, after preparation.
Some people have a greater risk than others of passing on genetic disorders to their children. A common example is pregnant women over 35.
The test is used to identify any genetic disease in your unborn baby.
Genetic counseling is recommended prior to the procedure. This will allow you to make an unhurried, informed decision about options for prenatal diagnosis.
It can be done sooner in pregnancy than amniocentesis, usually about 10 to 12 weeks of pregnancy.
Chorionic villus sampling does not detect:
A normal result means there are no signs of any genetic defects in the developing baby. However the test could miss some genetic defects.
This test can help detect more than 200 disorders. Abnormal results may be due to a number of different genetic conditions, including:
Talk to your doctor about the meaning of your specific test results.
The risks of CVS are only slightly higher than those of an amniocentesis.
Possible complications include:
When CVS is performed after 9 weeks gestational age, limb problems are no more frequent than in pregnancies without such testing.
If your blood is Rh negative, you may receive RhoGAM to prevent Rh incompatibility.
You will receive a follow-up ultrasound 2 to 4 days after the procedure to make sure the pregnancy is proceeding normally.
Simpson JL, Holzgreve W, Driscoll DA. Genetic counseling and genetic screening. In: Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics:Normal and Problem Pregnancies. 6th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2012:chap 10.
Simpson JL, Richards DA, Otao L, Driscoll DA. Prenatal genetic diagnosis. In: Gabbe SG, Niebyl JR, Simpson JL ,eds. Obstetrics: Normal and Problem Pregnancies. 6th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2012:chap 11.
A.D.A.M. Health Solutions, Ebix Inc., Editorial Team: David Zieve, MD, MHA, and David R. Eltz. Previously reviewed by Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington. Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Bellevue, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine (5/31/2012)
For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.
UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, gender identity, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.
Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.
For UPMC Mercy Patients: As a Catholic hospital, UPMC Mercy abides by the Ethical and Religious Directives for Catholic Health Care Services, as determined by the United States Conference of Catholic Bishops. As such, UPMC Mercy neither endorses nor provides medical practices and/or procedures that contradict the moral teachings of the Roman Catholic Church.
© UPMC Pittsburgh, PA, USA UPMC.com


text:
quote:My 3570k is at 4.7 and rarely goes over 45deg C
quote:Do yall just use HDTVs for monitors or do you insist on gaming monitors?
quote:I haven't completely crossed into forever alone status, so I only have one monitor at the moment.
quote:What do people think of ASRock motherboards? They're a new player to the game since my last build so I don't know much on them.
quote:Assuming all the connections work, will I be able to control all of the fan speeds from my desktop? Or would I be better off investing in a fan controller like
quote:ASRock Z77 Extreme6


text:
Tested by the Good Housekeeping Research Institute
Waring Pro Breakfast Express Professional Belgian Waffle/Omelet Baker WMR 300
Product Review
About GHRI Ratings
XGood Housekeeping Research Institute (GHRI) ratings are based on laboratory tests conducted by our scientists at the U.S.'s foremost consumer products evaluation laboratory, and incorporate consumer feedback. GHRI is situated on the 29th floor of the Hearst Tower in New York City and is staffed by chemists, engineers, nutritionists, textile specialists, culinary experts, and other scientists.
Using state-of-the-art equipment, GHRI experts test consumer products — from microwaves to mascaras — for their performance, safety, and, with the help of volunteer testers, ease of use.
Established in 1900, before there was a Federal Drug Administration or a Federal Trade Commission, GHRI has always been the most trusted source consumers can rely on to choose products that are safe and effective.
If your son loves big Belgian style waffles but your daughter prefers pancakes, you can make both at once in this large model. It has two round chambers, one a grid, and the other that you can use to cook a flapjack, omelet, or even fried eggs at the same time as the waffle. Halfway through, you flip the unit over to make sure both items cook evenly. Bonus: This model comes with a measuring cup for more consistent results.
Type: Belgian
Manufacturer's Warranty: Five year limited warranty
GHRI Tested: Waffle Makers
- All-Clad 2 Square Belgian Waffle Maker 99011
- All-Clad Classic Round Waffle Maker 99012
- Black and Decker Brushed Stainless Steel Belgian Waffle Maker
- Black and Decker Brushed Stainless Steel Rotary Belgian Waffle Maker
- Calphalon No Peek Waffle Maker
- Chefs Choice Classic Wafflepro 852
- Chef's Choice Belgian Waffle Pro 850
- Chef's Choice WafflePro Express 840 B
- Cuisinart 4-Slice Belgian Waffle Maker WAF-100
- Cuisinart Classic Waffle Maker WMR-CA
- Food Network Signature Series Belgian Waffle Maker
- Hamilton Beach Flip Belgian Waffle Maker 26010
- Hamilton Beach Waffle Baker 26020
- KitchenAid Pro Line Waffle Baker
- Krups 65475 Waffle Maker
- Oster Flip Belgian Waffle Maker CKSTWFBF21
- Presto FlipSide Belgian Waffle Maker
- Proctor Silex Belgian Waffle Baker 26008
- Proctor Silex Waffle Baker 26500Y
- VillaWare Belgian Flip Waffle Maker
- Waring Pro Breakfast Express Professional Belgian Waffle/Omelet Baker WMR 300
- Waring Pro Professional Double Belgian Waffle Maker WMK600
- West Bend Rotary Waffle Maker 6201
Special Offer


text:
Why would christ have had sexual relations with women and this be uknown?
Two questions here, "Why would christ ha ve had sexual relations with women?", "Why would this be unknown?"
To answer the first question, why not? If he really existed, as told to us, then he was a man with the same hormones and bodily functions as any other man. It would seem totally real to me, if (again) he actually existed.
Now, to answer the second question, because the books that we know as the "bible" came through Constantine and the councel of Nicea. These were some of the same males who created the catholic church. Apparently they don't like the thought of adult men procreating with adult women. Instead they support and hide pedophile priests who rape little boys. So, basically, modern religions and books come from really sick boys. But, if you read the talmud, it's even sicker.


text:
Error 404
Uh oh! Something went wrong.
Is it me you're looking for?
Unfortunately, this page doesn't exist. Check the URL for spelling mistakes or errors, or if you followed a link from somewhere, please notify them that it is broken.
If you can't find what you're looking for, try looking in the following locations.


text:
Kudox Vera Towel Warmer Chrome (H)914 (W)610mm
- Product rating
This radiator is suitable for use with hot water central heating systems only. Supplied with solid wall fixings kit and bleed plugs.
- 5 years Warranty
- Fixings supplied
- Valves not included
Read moreabout Kudox Vera Towel Warmer Chrome (H)914 (W)610mm
- Brand
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- Check stock in store Stocked in store
[This is a block of tabs..]
Product Details
Technical specifications
Height | 914mm |
Width | 610mm |
Depth | 153mm |
Wall to center of inlet | 116mm |
BTU | 794Btu |
Bar measurement | 5bar |
Heat output | 233 W |
Construction material | Steel |
Weight | 7.8kg |
Product reassurances
Choose a convenient delivery date on 1000's of products
45 day returns policy
Customer support team - 0333 0143357
Free delivery on orders over £50
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Excludes Next Day Bulk delivery goods