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What do you think of this new web video from Governor Mitt Romney's presidential campaign? Sound off below…
2/27/15 at 7:07 am
your turn
2/26/15 at 9:08 pm
VIDEO: Who Is 'Jihadi John'?
2/26/15 at 8:22 pm
Can you give someone you don't like the benefit of the doubt?
2/26/15 at 8:07 pm
VIDEO: Col. Allen West Asks, Has the US Already Surrendered to ISIS?
2/26/15 at 6:57 pm
Questions, Comments on Tonight's Show?
2/26/15 at 10:04 am
2/25/15 at 9:22 pm
What do you think about net neutrality?
2/25/15 at 9:00 pm
Pick a topic and BLOG!
2/25/15 at 8:46 pm
VIDEO: Boko Haram Teaming Up with ISIS?
2/25/15 at 8:03 pm
VIDEO: Our Worst Nightmare – ISIS Terror Growing from Within the U.S.
2/25/15 at 7:58 pm
Who is more destructive to the relationship between the U.S. and Israel?
2/25/15 at 6:57 pm
Questions, Comments on Tonight's ON THE RECORD?
2/25/15 at 2:44 pm
Someone needs to ask President Obama this question — click
2/25/15 at 2:40 pm
2/25/15 at 2:37 pm
Viewer email
2/25/15 at 12:56 pm
Documentary about Former Secretary of State James Baker
2/25/15 at 10:17 am
Which matters more in a President?
2/25/15 at 8:30 am
VIDEO: The Standoff Over DHS Funding – Proof That Washington's Insane!
2/24/15 at 9:45 pm
You just can't make this stuff up …
2/24/15 at 9:00 pm
Pick a topic and BLOG!
2/24/15 at 8:22 pm
VIDEO: ISIS Running Rampant But US Strategy on 'Right Track'?
2/24/15 at 6:57 pm
Questions, Comments on Tonight's ON THE RECORD?
2/24/15 at 3:25 pm
2/24/15 at 8:07 am
blog ….
2/23/15 at 9:00 pm
Pick a topic and BLOG!
2/23/15 at 8:46 pm
VIDEO: ObamaCare Architect Ripping Off Taxpayers Again
2/23/15 at 8:06 pm
VIDEO: Terror Threat Puts Malls Across America On Edge
2/23/15 at 8:00 pm


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HTC Unveils New One M9
3/2/2015 3:31AMHuawei 'Watch' Enters Wearable Market
3/1/2015 12:24PMWill the Real Warren Buffett Please Stand Up?
2/26/2015 6:00PMYes. No. Maybe: CPACers on Potential 2016 Candidates
2/27/2015 5:06PMTop Takeaways From Warren Buffett's Letter
2/28/2015 6:02PMLife Without a Cellphone Carrier
2/27/2015 6:16PMWinter Is the Worst...Except for These Businesses
2/27/2015 4:12PMKazuo Ishiguro Uncovers 'The Buried Giant'
3/1/2015 12:01AMBlack Hole 12 Billion Times Bigger Than Sun Found
2/26/2015 8:24PMSamsung Galaxy S6 and Galaxy S6 Edge First Look
3/1/2015 12:30PMThe Best Phone You Can't Get in America
2/24/2015 7:20PMShakhtar Donetsk Soccer Team Displaced by Ukraine Conflict
3/2/2015 7:40AMA year ago, Shakhtar Donetsk was poised to become one of Europe's soccer giants. But when Donetsk became the epicenter of the conflict in Ukraine, Shakhtar was forced to relocate more than 600 miles away. Photo: AP.
Jerry Seib: Foreign Policy Dominates Talk on Capitol Hill
3/2/2015 6:00AMYounger Japanese Could Get Their Voices Heard
3/1/2015 8:29PMThousands March for Slain Russian Opposition Leader
3/1/2015 2:46PMThe Window Screen That Cleans the Air
2/27/2015 7:26PMSaudi Prince's N.Y. Apartment Lists at $48.5 Million
2/26/2015 1:24PMA Manhattan triplex apartment with three panic rooms, an indoor Jacuzzi and a royal pedigree hits the market for $48.5 million. WSJ's Stefanos Chen has the details. Photo: Evan Joseph
Scientist Explains Why We Can't Agree On #TheDress
2/27/2015 1:58PMThe KRGT-1: Keanu Reeves' Dream Motorcycle
2/27/2015 1:55PMHere's a Thing: Google Maps' Secret Weapon
2/26/2015 10:00AMMarie Kondo Sparks a Cult of Clean Up
2/26/2015 1:26PMWho Are the Three U.S. Residents Arrested for ISIS Ties?
2/27/2015 5:59PMThree U.S. residents were arrested on February 25 for trying to join or aid ISIS. Here's how the FBI learned about them—and eventually stopped two of them from traveling to Syria.
Putin Political Opponent Shot Dead in Moscow
2/27/2015 7:22PMJeb Bush: World Engagement Is Key to Defeating ISIS
2/27/2015 5:55PMApple Facing New Patent Lawsuit
2/27/2015 1:48PMWill Homeland Security Funds Package Pass Congress?
2/27/2015 11:14AMIBM Cloud: Who's sharing your cloud?
12/15/2014 4:17PMIBM Cloud: Is your cloud built for apps?
12/15/2014 4:20PMEGA Master
10/11/2013 5:04PMBringing affordable healthcare to everyone
12/9/2014 5:54PMStar Trek 'Spock' Actor Leonard Nimoy Dies at 83
2/27/2015 4:56PMLeonard Nimoy, the actor best known for playing the cerebral, half-alien Spock on "Star Trek," died Friday, according to his talent agent, Bob Gersh. He was 83 years old. Photo: AP
Joe Morgenstern Reviews 'Queen and Country'
2/27/2015 1:48PMA Future Without Passwords?
2/27/2015 1:51PMMoneyologist: Family Tragedies and Financial Woes
2/27/2015 1:52PMViral Wrap-Up: Let It Snow
2/27/2015 6:30AMUnder Armour Foresees Electronic Clothing
2/27/2015 4:13PMAthletic gear company Under Armour is investing over $700 million on fitness apps. WSJ's Sara Germano reports. Photo: AP
FCC Ruling: What Does It Mean for Consumers?
2/26/2015 5:26PMFacebook Launches Suicide Prevention Initiative
2/26/2015 4:13PMIslamic State's 'Jihadi John' Named, and More
2/26/2015 12:02PMNet Neutrality Explained
2/25/2015 2:45PMWhy Are Snails Trending in Asia?
2/27/2015 11:34AMSnails have spawned antiwrinkle creams, lotions and masks, all full of the slimy gastropods' oozy mucus. Photo: Wilawan Watcharasakwet/The Wall Street Journal

subset: commoncrawl


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We buy and sell Classic Cars, We sell Magnum 500 Wheels, Ford Styled Steel Wheels, Mopar Rallye Wheels, Pontiac Rallye Wheels, Buick Rallye Wheels, Olds Rallye Wheels, and Chevrolet Rallye Wheels. We also stock and sell Scott Drake Reproduction Mustang Parts. We are certified Classic Car Appraisers.
We started Blue Oval Ranch, Inc. because we have a strong passion for Classic Vehicles. While our Company name hints at being a Ford fan, we pretty much love all the manufacturers across the board and recognize something special in all the different classic vehicles. Please give us a call or stop on by, we are located in Salem, Oregon, 503-910-2085.


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MTV asked Gosling to perform some selections from his "Hey Girl" meme. It's everything you hope it would be, if you hope for Ryan Gosling talking to you and being dreamy.
Coming soon: the "Hey Girl" movie.
MTV asked Gosling to perform some selections from his "Hey Girl" meme. It's everything you hope it would be, if you hope for Ryan Gosling talking to you and being dreamy.
Finally. And Bruno Mars.
Jack Ü Just Pulled a Surprise-Release With Its Debut LPThe 10-song project is titled Skrillex and Diplo Present Jack Ü.
Will Forte Spiced Up Seth Meyers' Wedding ToastAs Hamilton, the bad guy with a heart of gold.
Denis Villeneuve Will Direct the Blade Runner SequelWith Harrison Ford confirmed to come back.
Empire Co-creator Danny Strong Addressed Lingering Rumors About the ShowAnd shared some fun tidbits.
Kanye West Breaks Down in Tears in New Interview; Discusses Drake, Paul McCartney, and More"That's never happened to me in an interview before."
What Should Happen Next Season on How to Get Away With MurderMore murder, one hopes.
Banksy's Gaza Kitten Is Shaming Your Internet Habits"On the internet people only look at pictures of kittens."
Watch the Visually Remarkable Trailer for Bill Plympton's Cheatin'It might be the prettiest, most unusual thing you see today.
Here's Where We Stand on True Detective Season 2It's not just a meme!
According to Jay Pharoah.
Empire Continues to Surge, Breaks On-Demand RecordEmpire is on pace to be broadcast TV's fastest-growing drama since the first season of House, in 2004.
A Timeline of the Abuse Charges Against Bill Cosby [Updated]Twenty-nine women have now publicly accused the comedian.
What TV Will Cubans Watch on Netflix?American fantasy shows are popular, for one.
Pimp My Ride, Like Your Entire Childhood, Was a LieXzibit, how could you?
Baz Luhrmann Tells Us All About His New Netflix Show, The Get DownAnd it sounds kind of like an Empire prequel.
Conan O'Brien, America's Comic Diplomat to Cuba"It's a form of humility to make yourself the butt of a joke with another culture."
Nashville Recap: Boardroom Blitz!Oops, I destroyed your empire.
New Accuser Says Bill Cosby Assaulted Her in 1984Heidi Thomas claims Cosby assaulted her at a mentoring session.
Do You Ever Intend to Actually Buy an Album Ever Again? If So, It'll Come Out on a Friday NowTuesday release dates are dead.
Focus is a giddy love letter to a lost art.
House of Cards Showrunner Beau Willimon on Frank Underwood's Worldview, the Nature of Power, and the Singularity"He would say ideology or morality is a form of cowardice."
The Americans Recap: Age Is Just a NumberPhilip grows closer to two teenage girls: his daughter ... and the asset he's seducing.
The Best Moments From House of Cards Season 2 in 14 GIFSEverything you need to catch up for season three!
Just Like American Idol, Empire Might Be Going on TourGet ready to see "Drip Drop" live!
Broad City Recap: Important Business Boat MeetingThe adventures of Vulvarine, her transitioning BFF, and the most disgusting man on TV.
Empire Recap: In the Name of the KingThis week's episode is jam-packed with inconsistencies, making it another prime example of how this show can go from intriguing to inept at a moment's notice.
Arrow Recap: Chains Keep Them TogetherBy now it's pretty obvious to everyone on Team Arrow that Oliver has a renewed death wish.
Drew Barrymore Is Finally Publishing Her Life StoryIn a collection of autobiographical essays.
The Kardashians Just Got the Largest Reality-TV Contract EverFor four more seasons of Keeping Up With the Kardashians.
"We're all in for a wild ride."
How Not to Get Away With Murder, According to HTGAWMAccording to HTGAWM.
What Lady Gaga's American Horror Story: Hotel Might Look LikeThe Grand Gagapest Hotel.
Will Smith Wants to Make New Music, But His Kids Are Making Fun of His Old-Man ProcessParents just don't understand.
College-Rape Documentary The Hunting Ground Plays Like a Horror MovieThe filmmakers' techniques are not subtle, but neither is their subject.
Neill Blomkamp's Alien Will Finish the Aliens Story LineIt'll be a sequel to the second movie in the saga, bypassing Aliens 3 and Resurrection.
Ice T Is the New Dora the Explorer We've Been Waiting ForWell, at least temporarily on Fallon.
That Time Drake Basically Turned His Album Into a Billboard ChartLife is hard ... unless you're Aubrey Graham.
Sand and Dancing Are Big in Beach Boys Biopic TeaserLove & Mercy focuses on front man Brian Wilson.
Daft Punk's Faces Unveiled in Sculpture, Sort OfThanks, Xavier Veilhan.
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What If Girls Were About Drug Dealers and Starred Amy Schumer?From Colin Quinn's new web series.
Amy Poehler Made a Pilot With the Godfather of Improv When She Was 23 and It Is So WeirdIt's called RVTV.
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If You See Elisabeth Moss Cry, Don't Worry — She's Loving It"I'm never happier than when I'm crying onstage."
Kanye West Unveiled a New Song, 'All Day,' at the Brit AwardsThey're five hours ahead of us with everything!
Viola Davis Will Get Away With Yelling at Supervillains in Suicide SquadShe's following in the footsteps of Pam Grier and Angela Bassett.


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Grieffon wrote:And here's Twilight dressed as Tara dressed as Twilight.
http://deathpwny.deviantart.com/art/Hoo ... -329884503
Grieffon wrote:@Grivous: I saw that a while ago. Hilarious, but that's bad parenting. Spending so little time to talk to your kid that you misinterpret a cartoon as a religion? Bonus for calling your kid insane on a place he might see.
Here's a similar one, hover the ponies image for text.
Mr. Sefrol wrote:Two Best Sisters Play - Resident Evil 4
This guy's really improving with each of these.
Biostar wrote:Epic Pony Battle of History- Queen Chrysalis vs. Discord
That might be the best Discord I've ever heard. Those lyrics were hilarious and accurate.
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I strongly urge you to accept your mortality. Do not let your fear of your inevitable death make you waste your own mortal life pursuing phantasms and delusions. Look at yourself in the mirror. For billions of years, those particles, which are currently looking back at you have circulated in the universe. But for a brief moment they have coalesced in you. Rejoice in the impressive instant until they dissipate whence they came.
Delight that you're a spark of life in the universe. Life is so much more vibrant and vivid without bronze age paranoid superstitions, that cloud and contract the mind with some empty and undesirable promise that sparks can burn forever. Our time is finite. This gives our lives meaning. This gives our lives purpose. This gives our lives urgency. Live life today; savor it.
Everytime I fail or do something wrong, I am met with a wall of insults. Sometimes I just can't take it. Other times I can just suck it up. The worst insult my dad could say to me, and he already has, is that he is disappointed in me or that he has lost all expectations in me.
And with being a nurse, my sister had to memorize every little thing of the human body. And she was always so stressed out.
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Added To Cart
Subtotal: $26.45
Items in Cart: 5
Polish your everyday look with the classic sophistication of a tennis bracelet! Crafted from your choice of platinum, 14K rose or 14K yellow gold embraced™ over sterling silver, this polished design dazzles with a collection of rounded square asscher cut 4mm simulated diamonds in prong settings.
The total diamond equivalent weight is approximately 15.21ct. The tennis bracelet is conveniently offered in your choice of 6-1/2"L, 7-1/4"L or 8"L and measures 1/8"W x 1/8"H. The bracelet secures with a slide insert clasp with a safety catch.
Part of the Brilliante® Platinum Embraced Collection. Made in China.
Necklace & Bracelet Clasp Types
Lobster Claw Clasp: As a traditional clasp style found in bracelets and necklaces, the lobster claw is generally reserved for heavier styles that may need added strength. The closure's shape is more oblong, similar to a teardrop shape, and is controlled by a tip that opens and closes the spring in the clasp. This type is also considered a more expensive finding that can add to the overall value of the jewelry piece.
Magnetic Clasp: The popularity of the magnetic clasp has greatly increased in recent years. It is a quick and easy way to secure jewelry while not having to fuss with a tiny clasp, which can be difficult if you have long fingernails, arthritic hands or other mobility challenges. A magnetic clasp relies on a strong internal magnet that works to pull both ends of the clasp together. In most cases, a magnetic clasp is used for light to medium weight jewelry pieces that do not put excessive stress on the magnet.
Slide Insert Clasp: This type of clasp is exactly as it sounds. With a box-like shape that is hollow on the inside, the wearer will slide the nearly-flat tab into the box until it clicks, indicating a secure closure. On some jewelry, a slide insert clasp will be accompanied by a side safety catch, which adds strength and security to the clasp. Although this type of clasp is found on both bracelets and necklaces, it is particularly popular on bracelet styles. These types of clasps are often reserved for more expensive jewelry.
Spring Ring Clasp: One of the most common closure types, the spring ring clasp is typically used for light to medium weight bracelets or necklaces. It is round in its design and features a small tip which controls the opening and closing of the spring. The circle then closes around another smaller loop or link at the other end of the strand.
Toggle Clasp: A toggle clasp is a narrow piece of metal, usually designed in the shape of a bar, which is then pushed through a circular ring to act as a fastener. Unlike the lobster claw or spring ring clasps, a toggle clasp is not controlled by a spring. The pretty design is less secure than other closure types, but is usually meant to be a big part of the design and is meant to "show". The clasp is an attractive way to secure a chunkier link bracelet or necklace.
Vermeil Plating: Pronounced "vermay," vermeil is an electroplating process in which 14K gold or higher is coated over sterling silver. Officially designated by the jewelry industry, items may only be sold as vermeil if they have a minimum thickness of 100 millionths of an inch (2.5 microns) of gold over the silver. Regular gold plating is less than 2.5 microns.
The "vermeil" technique of plating sterling silver with gold originated in France in the 1750s. It differs from "gold filled" or "gold plated" in terms of the thickness or thinness of the microns over sterling silver. "Gold filled" pieces have a much thicker layer, between 15 and 45 microns, which is mechanically bonded to the base metal with heat and pressure. Vermeil is a more expensive version of "gold plated". It does not wear off as quickly as gold plating does. However, over time, vermeil wears off and therefore will require re-plating.
Gold/Platinum Embraced Silver or Bronze: Our platinum and gold embraced collections feature layers of platinum or gold over sterling silver or bronze for a lustrous, radiant finish everywhere you look and touch.
To care for your plated jewelry items:
Platinum Plating: Platinum can be used as a finish coating over sterling silver or copper alloys. Its bright, pure luster enhances the brilliance of gemstones and does not discolor or oxidize. Platinum plating is also characterized by its good resistance to surface abrasion, making jewelry pieces more durable against everyday and long-term wear. Over time, platinum plating will wear off and therefore will require re-plating.
On the Mohs Scale, which measures the hardness of minerals, cubic zirconia is an 8.0 to 8.5. It is important to understand that hardness is not necessarily related to durability. Even though diamond is the hardest mineral (10.0 on the Mohs Scale), it can still be chipped or broken.
The only ways to tell the difference between cubic zirconia and diamond are by use of a thermal probe, by weighing the loose stone or by microscopic examination of surface features and inclusions. Cubic zirconia weighs approximately 65% more than diamond. Therefore, while a 6.25 mm round diamond weighs about 1.00 carat, the same size cubic zirconia weighs about 1.65 carats. If you know the weight of a cubic zirconia, you can figure out the diamond weight equivalent by multiplying the cubic zirconia weight by 0.6, or 60%.
Few natural diamonds on the market today are perfectly cut, and those that are cost much more than the usual diamond. Unleashing the fire, beauty and brilliance of a stone depends on its precise cut. Simulated diamonds are an excellent balance between quality, beauty and price.
Brilliance: The white light leaving a jewel, traveling upward, which is visible to the eye. Brilliance is sometimes referred to as "sparkle."
Dispersion: Flashes of rainbow colors. Also called "fire."
Hardness: Resistance to scratching. The higher the number, the more resistant.
Luster: The shininess of a jewel.
Toughness: Resistance to breakage.
About the Collection The most elegant dreams include luxurious diamonds, gold and platinum. Realize Your Dreams™ with Brilliante® simulated diamond jewelry. Designed exclusively for EVINE Live, Brilliante jewelry features high quality AAA simulated diamonds set in Platinum Embraced™ or 18K Gold Embraced™ sterling silver or bronze.
By combining the eternal elegance of platinum and gold with the eye-catching sparkle of simulated diamonds, Brilliante lets you enjoy the look and feel of real...at prices that make sense for your lifestyle. In addition, each classic, versatile design effortlessly transitions from day to evening...so you can wear Brilliante anytime.
Discover the luxurious appeal of Brilliante today and see how easily - and affordably - you can bask in the glow of diamond-like elegance.
About The Guest Join on-air guest, brand expert and jewelry aficionado, Laurel Ostby, and experience the luxury of Brilliante®. With a warm, engaging personality and a background in jewelry sales, marketing and merchandising, Laurel is your personal tour guide to discovering the beautiful world of Brilliante.


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Roll Over Image to Zoom
Lily Elephant Decorative Pillow
No longer available
- Overview
Soft Mediterranean colors are combined with hand-stitched detailing and a woodblock print to create this boutique-style decorative pillow. Rich with details including French knots, chain-stitch embroidery and a pink elephant appliqué, this top-of-the-bed pillow will be cherished for years.
- 12 x 24"
- Pure cotton.
- Appliquéd elephant is embroidered with satin-stitch and French knot details.
- Reverses to a pink, white and green stripe.
- Machine wash.
- Imported.
- Dimensions & Care
- Machine wash in cold water; gentle cycle.
- Use only nonchlorine bleach, if needed.
- Tumble dry on low heat.
- Warm iron as needed.
- Shipping Info
Please allow 5-7 business days for delivery. Delivery estimate includes monogrammed and gift-wrapped items.
You May Also Need
PBK Luxury Loft Pillows
$14 – $29
PBK Down Alternative Bedding
$99 – $149


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quote:check your junk box
quote:Location Date Local Time Activity Louisville, KY, United States 11/15/2012 1:23 P.M. Origin Scan
quote:Still no email. I got a 16gb by the way
quote:Just got a backorder email. Not very happy
quote:What makes this better than the s3 or note 2?
quote:havent got teh backorder email yet, still have hope.
quote:If you factor in all the money you will save by using T-Mobile monthly plans, the Nexus 4 will save you over $1,000. Plus it's a pretty sweet phone. I'm buying 2.
quote:did you order the 16 or the 8gb?
quote:I ordered the 16gb AT 10:51 CST.
quote:i got mine a minute earlier; 16GB at 10:50 CST and i have a UPS tracking # now that says its in louisville.


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quote:I don't think it was lies per se, they just talked out their ass. And for a time in the 80s, it really did whallop the straight community. Nothing like it did to the gays but it was an epidemic in many cities, due one dude shooting up and getting it and then fricking a bunch of woman. I think most of that curtailed with needle exchange programs.
quote:2. Most HIV/AIDS infections will be among heteros by 1980.
quote:AIDS was first clinically observed in 1981 in the United States The World Health Organization first proposed a definition for AIDS in 1986 By September 1982 the CDC started referring to the disease as AIDS. ...in 1986, LAV and HTLV-III were renamed HIV
quote:Go back in time. In the mid 80s
quote:Try to learn how to read. I amended my quote.
quote:Or, perhaps you were not around in the mid 80s when Reagan was blamed for AIDS?
quote:Or perhaps you think Reagan was President in the 90s? How sad.
quote:Yes, I was sexually active in the 80's, and no, I don't remember anyone saying that about Reagan,
quote: 1. America will go totally metric by 1970.
quote: 2. Most HIV/AIDS infections will be among heteros by 1980. 3. Soccer will be the most popular sport in the US by 1970. 4. People will reject the suburbs and live downtown.
quote: 5. Computers will replace the need for accountants.
quote:4)The oil shortage of the early '70's
quote:Number 1 should've happened. Not using metric is dumb as hell.
quote:There was an oil shortage due to the OPEC embargo. Lines were horrible. Flags went up and down if stations had gas.
quote:AIDS was called GRID when first diagnosed among gay men. Late 70s, very early 80s


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Broadous School
The Broadous School demonstration project was part of the Los Angeles Department of Water and Power's Cool Schools program, of which TreePeople was a major partner.
The challenge
The campus of the Hillery T. Broadous Elementary School in Pacoima was suffering from periodic flooding that sometimes reduced student attendance by as much as 15 percent.
A sustainable solution
With the support of the school district, the site was retrofitted to capture, treat and hold all the rain falling there, reducing the flood risk and recharging the groundwater.
An underground infiltration system, a swale, permeable ground cover, and strategically planted trees replaced over 30 percent of the asphalt that once covered the campus. Energy use was also reduced by shading and cooling the buildings and their air conditioning units.
Construction of the infiltration system was completed in February 2001. Three tree-planting events, involving the school's students and community members, completed the transformation of the campus.
A collaborative effort
The Broadous retrofit was a collaboration involving TreePeople, the L.A. Unified School District, the Department of Water and Power, Pacoima Beautiful (a community action group), the city council district, landscape architects and the engineering firm of Montgomery Watson (now MWH).
Key components
The project's three components – a swale, a stormwater separator and an infiltration basin – work together to capture and clean stormwater runoff and recharge the groundwater. They also reduce flooding in the downstream area.
A swale is a mulched or vegetated strip that slows runoff and enables the water to soak into the soil. It also begins the process of cleaning the runoff by filtering pollutants from it.
Originally, the swale we created for the Broadous school was planted with vegetation. Unfortunately, the school district removed the vegetation and paved the swale to simplify the movement of delivery trucks.
This means that the swale no longer serves its primary function of slowing and cleaning runoff. But it still helps channel water to the treatment and infiltration systems we created on site.
The separator is a stormwater treatment device that uses the mechanics of moving water to settle sediment, skim off pollutants and separate trash from the runoff before it's delivered to the infiltration basin. The unit used for the Broadous project is a Vortechs 9000.
Infiltration basin
Two hundred twenty plastic chambers shaped like inverted "U"s make up the infiltration basin. They create temporary underground storage for campus runoff, which gradually percolates through the soil to recharge the groundwater.
The separator and infiltrators work silently beneath a new grassy playing field.
Further details on this project can be found in Rainwater as a Resource, TreePeople's report on three of its stormwater demonstration sites.


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Unlock your personal NFL Now stream by signing in to NFL.com
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Former "American Idol" contestant Jason Castro explains to Access how his new album, "Only a Mountain," reflects his personal journey. Also, how has his music changed since he got married and became a father?
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Cinderella herself, Lily James, was the belle of the ball at last night's Hollywood premiere of the film. We caught up with the actress in the rare moments when she wasn't busy snapping photos with the little girls in attendance at the debut to talk about the moment she first felt like the Disney princess and her onscreen Prince Charming.
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Fans were excited to see the exciting season five finale of Downton Abbey. Meanwhile, Maggie Smith has announced the next season will be her last.
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Game of Thrones alum Richard Madden may have had his horseback riding skills on lock before shooting Cinderella, but it turns out the same could not be said for ballroom dancing. Watch our interview with the actor from last night's Hollywood premiere of the Disney film for more on preparing for the role and his first impression of costar Lily James.
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Taylor Swift told the Telegraph U.K. that she refuses to discuss frenemy Katy Perry during interviews because she doesn't want to give the tabloids something to write about.
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Navigate Shop
Our store hours are 11:00-18:00 Monday to Friday.
We can be reached at +44 (0)20 7235 7680 during Shop business hours. email@example.com
The Treatment Room No. 2
£100 (Excludes VAT)
Giving us unprecedented access to his designs, Anderson came to our Bruton Place headquarters and sketched his much anticipated womenswear line before it hit the catwalk.


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Start learning with our library of video tutorials taught by experts. Get started
Explores the world of hypersyndication—showing how to distribute content across all media platforms quickly and more efficiently.
"I send my customers to you all the time to learn. If I had more time in the day I would live on your site!" —Alan B.
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Good shoes can be a great investment, especially if you take advantage of the skills of shoe repair pros. Quality shoes can last for decades with proper storage, cleaning and maintenance. Consider these tips for bringing new life to old soles:
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Local Articles in Ypsilanti
Don't throw out those blue suede shoes! Learn more about saving money by investing in shoe repairs.
After decades of losing business, repair shops are reaping a benefit of the sluggish economy as people hang on a little longer to the things they already own.
Customer says she can't wear her shoes because the zipper repair looks bad. Shoe repair shop says they did a good job and won't give her a refund.
Angie's Answers
You would have to have a shoe repair shop evaluate them - some heels are hollow except at the tip so you might not be able to shorten them and retain the necessary strength - others are solid, so he would have to look at them. Might be able to just remove heel cap, cut down, and put heel cap back on.
Bear in mind that cutting the heels down will rock the shoe "backwards", so you will be walking on sole further back on the shoe - if the unthickened sole part betweenthe heel and the ball of the foot would be walked on because of this, you might have to pay him to add leather there to, which might mean resoling the entire shoe - could get pricey, if these are not worth hundreds of $.
As for evaluating a shoe repai place - only thing I can think is if these are pricey shoes, call store and see if they recommend a particular place. Otherwise Search Angies List for sheo repair places and reviews.
Shoe Repairing reviews in Ypsilanti
As to the Men's boots that needed to be stretched - my husband came with me to try them on and there was no change to the boot. He decided to leave the boots there for another 3 days as they are going to stretch it more.
I would not recommended Rawhide Boot & Shoe Repair Shop. They tell you what you want to hear, make sure you pay up front and do cheapest/easiest for them. They have your money and won't do anything to correct this. Outcome is not good!
This time I dropped off the shoe and said I would wait. I was told I could not. I said I always come in the date it was to be ready and then wait while they do the work then. I was told to go somewhere else if I didn't want to wait a week.
I said I would wait a week.
I arrived the morning it was to be ready and was told to come back between 4:30 and 5:00.
I came back at 4:35 and was told it would not be ready until Monday.
I stopped by Monday evening and it wasn't ready.
I stopped by Thursday evening and it wasn't ready.
I was told I would receive a phone call when it was ready and there would be no charge.
The next week I received a call and picked up the shoe and was charged the estimated cost.
I got home and the shoe is unwearable. The new stitch looks good from the outside but the knot on the inside is so big it hurts my big toe.
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Search Results for e-o tech scope 04513
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US Optic MR-10 1.8-10x 37mm SN-3 T-PAL Parallax, Type Ill Scope with EREK Knob
Enforcement professionals. This riflescope is a perfect fit for the L/E marksman. Statistics have ... US Optic 1.8-10x 37mm SN-3 T-PAL Parallax, Type Ill Scope with EREK Knob represents probably ... the most "all around" scope by US Optics that we offer. 1.8x magnification provides excellent close ... quarters capability while 10x power gives the ability to shoot to 1000+ yards. This USO Scope is great ... Riflescope by U.S. Optics from SN3 Series features excellent low light ability provided by standard ... 37mm objective lens. This US Optics 1.8-10x37mm SN-3 Riflescope has Turret Parallax Adjustment. ... This can be had with the knob on the left, right or top of the scopes turret. Reliable adjustments... |
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Powder Coated Light Fixture Offers Corrosion Protection
The WFH series fixture is one of the most versatile in our offering. It is UL listed for hazardous environments where protection is needed from liquids or gasses, dusts, and fibers and rated for heavy hose down environments.
A one-piece housing with powder coated finish offers excellent corrosion protection and extremely high reflectance. A heavy-duty door frame, heavy duty latches and 3/16 inch thick lens complete the package, making the WFH the superior choice for industrial manufacturing, food processing, and other hazardous & wet locations.
Available with up to six T8 and T5HO lamps, a lamping configuration is available to suit your needs. The WFH is also available in a wide range of AC and with an emergency battery backup option.


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La Crosse repeats in Class 1A
By CONOR NICHOLL
WICHITA -- The La Crosse High School boys' track team was the heavy favorite entering the Class 1A state track and field meet after it returned virtually all its top athletes from a classification record 84 points last spring.
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By CONOR NICHOLL
WICHITA -- The La Crosse High School boys' track team was the heavy favorite entering the Class 1A state track and field meet after it returned virtually all its top athletes from a classification record 84 points last spring.
Still, the Leopards continually improved throughout the season, had multiple big performances from athletes who had never been to state and again received strong weekends from seniors William Storie, Levi Morss and Kip Keeley.
"We are never one to back down from a challenge," Storie said. "We always talk about adversity and overcoming it, and that's what separates us from everyone else."
This weekend, La Crosse finished with 87 points and set another 1A boys' mark for its second consecutive Class 1A title. Centralia finished as runner-up for the second straight year with 46.75 points. The Leopards' back-to-back crowns are the second and third championships in any sport in school history.
"Team-wise, we accomplished our goal," said Morss, who won four golds.
On Friday, the Leopards went 2-4-5 in the shot put with Keeley and sophomores Sheldon Schmidt and Cole Kershner. None of the athletes had qualified in shot put before this year.
"I am really proud of our throwers," Storie said. "They came, and they competed."
Then La Crosse finished 1-2 in javelin with junior Lucas Moeder and Keeley; it was Moeder's first state trip.
"It's nice to see we have these prodigies coming in," Morss said.
On Saturday, Morss highlighted the day with championships in the 100- and 400-meter dashes in 10.97 and 50.09 seconds, respectively. Coupled with a Friday gold in the long jump, Morss finished with three individual golds. Then, he anchored the 1,600 relay in a gold-medal time of 3:29.68. Last year, he had only one gold in the long jump.
He had less competition when Otis-Bison junior Jordan Hoffman hurt his upper leg early in 100 and scratched out of the 400.
"I felt alone," Morss said. "It was bittersweet. I liked someone that can push me and without him there, I felt like I maybe didn't perform to the best I could."
Morss wanted four golds, but had false started in the 200 at the regional last week. On Saturday, he replaced sophomore Andrew Jay on the 1,600-meter relay.
Storie took second in the 300-meter hurdles after he was fourth last year. The senior ran in his familiar red socks.
"I wanted to leave my signature every time I raced," Storie said. "They saw me, and they knew who I was."
He had the initials "B.R.D." written on his shoes in black ink in honor of his friend Ben Derr from La Crosse. Derr passed away in an accident the week before regionals two years ago. Every time Storie settles in the blocks, he looks down at the initials.
"He is my inspiration," Storie said. "He has really driven me."
Storie ran 40.32 and finished behind Clifton-Clyde junior William Ohlde. Storie also ran the opening leg of the 400 relay that finished fifth in 45.03 and was the opening leg on the 1,600 relay.
"I have working really hard all year and focusing mainly on the 300 hurdles," Storie said. "It was kind of disappointing that I finished in the place that I did. It was still something to be proud of."
Morss and Hoffman, Rush County rivals, were supposed to match up in the 100 and 400 finals. Hoffman qualified first in the 400 and fourth in the 100. In the 100 finals, though, Hoffman hurt himself early in the race and took fifth in 11.38. Morss ran well and believed he could have won the race even if Hoffman had been in the competition.
Morss' 10 points for the title effectively earned the team crown.
"I had a good start," Morss said. "I had a good time. I had a good race."
Barrientes collects discus title
Sylvan-Lucas senior Paul Barrientes threw in the 130s and low 140s in the discus during the regular season. Last week, Barrientes threw 147-1 at the Valley Heights regional to qualify for the second straight year. Barrientes and his coach Ryan Batchman watched YouTube videos, and changed his spin speed.
"Was kind of coming off slow and that forced a lot of my throws out of bounds, so I moved speed up and getting down the middle more, focusing more on lower half of my body and my hips, getting a good throw out of it," Barrientes said.
On Friday, Barrientes had a frustrating showing in the Class 1A shot put when he didn't make finals. A morning later, Barrientes was ecstatic after he pulled off the 1A discus title with a throw of 154-9.
"I got a little angry, and then I settled down, and then I focused that anger on throwing the disc and it helped," Barrientes said.
It marked the first state crown for the Sylvan or Lucas-Luray - they consolidated three years ago - since Lucas-Luray's Dustin Feil won the 1A discus in 1999. The gold was also his first state medal.
"He is probably one of the greatest coaches I have ever had in my life," Barrientes said. "It really means a lot to get that championship for him. That was the main thing. That was the goal for today, to get that championship for him."
Barrientes, the No. 3 seed, went 150-4 in prelims to set another personal best and move into second place. After a foul on his fourth throw, Barrientes narrowly fouled on his fifth throw when stepped out of the front of the ring after a big toss.
"Saying around 160," Barrientes said.
Barrientes was a little frustrated, but Batchman told him, "Let it be smooth" for his final throw. Barrientes calmed down, said a little prayer and threw his winning toss on his last attempt, five inches better than Langdon-Fairfield senior Brennyn Pankratz.
Pankratz was the last thrower in the competition. Barrientes went and stood behind one of his coaches. After Pankratz's throw was short, Barrientes hugged his coaches, family and his mom, who said "I told you so!"
"I was really happy," Barrientes said.
Weskan earns relay title
Weskan was nearly nine seconds behind Stafford when Coyote senior Sam McKinney took the baton on the anchor leg of the Class 1A 3,200-meter relay.
"If somebody would have told me that we would have ended up catching them, I probably wouldn't have believed them," McKinney said.
Instead, McKinney ran a 1:59 split and caught Stafford freshman Mikey Augilar in the final 50 meters. Weskan, which also had seniors Brendan Escamilla, junior Tyler Compton and senior Nick Smith, finished in a school record of 8:17.65, besting the previous mark of 8:25.
"Our guys have been working hard all season," McKinney said. "We have been running in the mornings."
McKinney was going to be happy with second. His main goal was the school record. With 200 meters left, McKinney looked up and saw he had a chance to get the mark, so he took off sprinting. Then, he turned into the last 100 and saw the gap between him and Augilar.
"I didn't realize that we were so close," McKinney said. "I tried my heart out to try and catch him."
McKinney also finished third in the 1,600 (4:33.85) and second in the 800 (2:01.31).
St. Francis wins boys' 400 relay, Atwood takes girls' relay
The St. Francis' 400 relay has juniors Logan Lampe and Derek Queen and seniors Thomas Douthit and Michael Leibbrant. All four Indians made their first trip to state this year. None of them qualified for the 100 prelims out of regionals.
"We are not fast enough to all be at the top of the 100, but we are just right there below," Douthit said.
Yet the Indians won the 400 relay in 44.39 seconds. At regionals, St. Francis ran 44.28 and held the top seed entering state.
"Through the year, we hadn't really had all four of us except for three or four times," Douthit said. "That was just running 45. We really didn't make our big step until regionals."
Atwood, seeded No. 1, won the 400 relay in 51.03 seconds and displayed impressive depth when senior Taylor Leitner and sophomores Lexy Leitner and Rohey Singhateh went 4-6-7 in the 100, respectively. Leitner finished fifth in the 200 (27.37), too. They were the first medals for Taylor Leitner, who has qualified in at least one event all four years. .
"It's nice to finally actually do as well as we should be doing at state," Taylor Leitner said. "I never do great at state. My junior year was bad. I guess just this year because it's my last chance. I knew we had a really good shot at everything. I guess motivation more than anything."
Heim wins long jump
Hoxie sophomore Carly Heim doesn't plan to hit a big jump on her first attempt of long jump and triple jump. However, at regionals and state, Heim often led from the start with a big jump. On Saturday afternoon, Heim went 17-1.5 on her first attempt in the 1A long jump. No one beat that mark.
"I think it's just coincidence," Heim said of the big early jumps. "I don't think I really do it on purpose."
On her second attempt, Heim delivered her gold-medal winning jump when she went 17-2.5. Heim also won the triple jump Friday morning - and then had more than 24 hours to wait.
"It's been a long day," Heim said. "I am just glad for it to be over."
At regionals, Heim benefited from a little bit of wind and went a career-best 17-11.75. On Saturday, Heim had a 1.8 mile per hour wind, just under the legal limit of 2.0, on her best jump.
"It helped a lot," Heim said. "Not as much as last weekend. I am just thankful to be here."


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I. Definition of the Prevention Area
Microbicides are products formulated for individuals to apply topically (vaginally or rectally) to reduce their risk of HIV and possibly other sexually transmitted infections. At present, this approach is experimental, although several broad-spectrum microbicides have been clinically evaluated. Microbicides comprise a subset of approaches to pre-exposure prophylaxis (PrEP); oral approaches to PrEP are addressed in a separate entry.
II. Epidemiological Justification for the Prevention Area
In generalized epidemics, women are at a disproportionate risk of HIV infection for biological as well as social reasons. Although condoms are highly effective in preventing HIV transmission, it can be difficult for women to negotiate safer sex because the male partner often controls whether a condom is used. Microbicides were initially proposed as a woman-controlled or -initiated prevention method for vaginal application, something a woman could use to protect herself.
The first microbicides studied were broad-spectrum compounds that were expected to inactivate HIV and other microbes by enhancing vaginal pH or by coating cell surfaces, preventing the binding of viruses or the entry of microbes into tissue. None of these approaches proved effective.
However, clinical trial results released in 2010 by the Centre for the AIDS Programme of Research in South Africa (CAPRISA) provided the first proof of concept for microbicide efficacy. This study, CAPRISA 004, found that a topical gel formulation of the antiretroviral drug tenofovir significantly reduced the risk of acquiring HIV and herpes simplex virus 2 (HSV-2) in women who use it regularly around the time of sex. However, in late 2011, the gel arms of another clinical trial evaluating daily use of one percent tenofovir gel were stopped early by the trial's data safety and monitoring board because there was no evidence that the gel was effective in reducing the risk of HIV acquisition. (This trial was also evaluating oral tenofovir and oral Truvada). Further analysis of data from this trial, known as VOICE (Vaginal and Oral Interventions to Control the Epidemic), is needed to explain the discrepancy between the two trial results.
Another trial evaluating vaginal use of one percent tenofovir gel is underway using the same dosing schedule as in CAPRISA 004. This trial, FACTS 001, is being conducted by the Follow-on African Consortium for Tenofovir Studies (FACTS) which expects to have data available in 2014. If FACTS confirms effectiveness of one percent tenofovir gel, additional steps will be needed before it can be licensed and marketed. Two safety and effectiveness trials of a vaginal ring containing dapivirine are scheduled to start in 2012.
Researchers are also evaluating whether these products could be safe and effective when applied rectally, given that anal sex carries an even higher risk of HIV transmission for heterosexuals and men who have sex with men. Developing a rectal microbicide is more challenging because the rectal mucosa is highly susceptible to HIV infection. Also, the colorectal tract has a greater surface area than the vagina, requiring a rectal microbicide to have greater coverage. Trials of a rectal formulation of tenofovir gel are moving forward.
III. Core Programmatic Components
Further studies are needed to confirm the safety and efficacy of tenofovir gel and other products being developed; it will be several years before this or any other microbicide is marketed. In the meantime, policymakers and program directors need to work closely with the community to put this potential prevention tool to best use. The following key activities will be necessary:
- Support of research to assess how the microbicide might be accepted and used in the local setting. What impact will it have on sexual risk-taking?
- Development of educational materials and campaigns to promote adherence and correct use while helping people understand the potential limitations of products that are only partially effective.
- Buildup of a stable supply chain and strategic distribution plan to ensure access to those who need the microbicide.
- Ensuring access to regular and routine HIV testing, especially rapid point-of-care HIV tests, to reduce the risk that people who are HIV-positive and are unaware of their HIV status will use the product.
- Performing surveillance for adverse events and for detection of any increase in HIV transmission or the possibility of individuals not yet on antiretroviral therapy developing drug resistance.
IV. Current Status of Implementation Experience
While an approved microbicide is not yet available, the clinical trials in Africa and India provide insights into how best to introduce microbicides into communities and fuel hope that women-driven prevention technology might further women's empowerment. For instance, one group in Pune, India, has explored how discussion of microbicides among couples could enhance partner communication about sex.
While the success of the CAPRISA trial is promising, additional work will be necessary to complete the critical next phases of research that could lay the groundwork for large-scale rollout. A number of additional trials over the coming years should deliver further results.
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The Microbicide Trials Network dropped tenofovir gel from its Vaginal and Oral Interventions to Control the Epidemic (VOICE) trial following a routine Data Safety and Monitoring Board review that concluded that tenofovir gel was not effective in preventing HIV in the women enrolled in the trial. VOICE, an HIV prevention trial, has been evaluating two antiretroviral approaches for preventing the sexual transmission of HIV in women--daily use of one of two different antiretroviral tablets (tenofovir or tenofovir emtricitabine) or of a vaginal gel. The trial has enrolled 5,029 women at 15 sites in Uganda, South Africa, and Zimbabwe, and had earlier discontinued the oral tenofovir. The study found no safety concerns with any of the study products. It is not clear why tenofovir gel did not reduce the risk of HIV acquisition among women in this trial when an earlier trial (CAPRISA 004, which followed a different dosing schedule) showed a reduction in risk. Complete analysis of the trial data will take place after the trial is completed and all of the data are analyzed. The trial team expects results to be available in late 2012 or early 2013.
This is the first clinical trial indicating the effectiveness of a vaginal microbicide in reducing HIV infection in women. Nearly 900 sexually active women aged 18 to 40 in Durban and Vulindlela, South Africa, were randomized to receive tenofovir or placebo within 12 hours before having sex and as soon as possible within 12 hours after having sex. Monthly support meetings with participants highlighted the importance of consistent and correct microbicide use, identified ways to overcome obstacles to use, and set goals for perfect adherence for each month. Despite this, 40 percent of the study participants used the gel for less than 50 percent of sex acts. After 12 and 24 months of follow-up, HIV incidence in the tenofovir arm was 50 percent and 40 percent lower than the placebo arm, respectively. HIV incidence among women with the best adherence was 54 percent lower than placebo, indicating that effectiveness was linked to adherence. Furthermore, the study found tenofovir safe. Despite the small sample size, this study provided "proof of concept" for tenofovir microbicide prophylaxis. More studies are needed to corroborate these findings.
Cited preferences for "dry" sex among certain populations in sub-Saharan Africa raise concerns about the acceptability of vaginal gel microbicides. To identify whether such use would be problematic, 118 in-depth interviews and 15 focus group discussions with women participating in a microbicide gel trial in Kwazulu-Natal and their partners collected detailed information on intravaginal insertions. Unexpectedly, 49 of 63 interviewed women and 4 of 8 men said the microbicide enhanced their sexual pleasure; the remainder reported no effect of the microbicide on their sexual experience. Participants stated that the gel increased sexual pleasure by making sex "hot," "tight," "smooth," and "dry." Women also reported enjoying the lubricating effect of the gel. According to this research, the notion of "dry" sex is not one of complete dryness, just lack of excessive wetness in the vagina. Furthermore, as intravaginal "potions" were commonly used to improve sexual pleasure among this population, a microbicide may be more easily understood in a local context using local terms. The authors conclude that microbicides may be more acceptable for HIV prevention than expected, as previous associations between intravaginal insertions and dry sex were "overstated."
This document contains the abstracts of all oral presentations and poster sessions given at the 2010 International Microbicides Conference. Organized by conference days, readers can browse through the content, search the document for authors or keywords, or scroll to the author index at the back of the document. The theme of this conference was "Building Bridges to HIV Prevention," which is reflected in the abstracts.
This study assessed the acceptability of the Duet® cervical barrier together with a gel in 103 primarily married women in peri-urban Zimbabwe. Women were randomized to use the Duet continuously for 14 days, then only use it before having sex; another arm was randomized to the same regimen in reverse sequence. Approximately 90 percent of the women reported adhering to their assigned regimen 80 percent of the time. Overall, acceptability was high. Half of the participants preferred using the barrier during sex, 39 percent preferred continuous use, and the remainder reported no preference. The most positive attribute women assigned Duet was "normal/natural sex." No serious adverse events were found among the study participants. Of note, 5 percent of women in both arms reported unspecified "fear" related to use. This study was small and only followed women for one month. Longer-term use may affect acceptability; adverse events may also differ with long-term use.
An in-depth review of the history of microbicide development for HIV prevention, this article also presents new microbicides under development. These include antiretroviral drugs and drug combinations that can be administered in different ways, including daily delivery and sustained delivery mechanisms. In addition to specifically targeted HIV replication, new product options related to timing of use can potentially improve product effectiveness. Potential new microbicides, however, come with concerns about toxicity and resistance. Additional challenges to microbicide development, such as need to remain stable in a tropical environment, are also addressed in the article. The author details concerns and further challenges to introducing a microbicide widely in a population, including knowing its safety profile among pregnant women or women who want to become pregnant. Despite recent encouraging news about microbicides, the road to their widespread and effective use for HIV prevention remains long.
Describing their in vitro and ex vivo testing of tenofovir, the authors make the case that preclinical testing of microbicide products has advanced tremendously over the last decade. Previous microbicides shown to cause cell irritation were not tested so extensively prior to their use in phase II and phase III trials. This study used human ectocervical and colorectal tissue to understand the effects of tenofovir gel on such tissue. In vitro tests found viscosity similar to other commonly-used vaginal and rectal lubricants, constant tenofovir release rates in the gel, and penetration of the drug into mucosal tissue, albeit at varying rates. The gel had no negative effect on vaginal flora, even in the presence of four different bacteria, including gonorrhea. Furthermore, tenofovir reduced the presence of HIV in the tests. Thus the authors conclude that tenofovir is effective and may be a viable candidate for pre-exposure prophylaxis in humans.
This press release from the Microbicides Development Program (MDP) summarizes the outcome of the MDP 301 trial that tested the effectiveness of PRO 2000 vaginal microbicide gel against placebo for HIV prevention. Disappointingly, data from over 9,000 women in four countries in Africa over 12 months (24 months in Uganda) found no difference in HIV acquisition rates between microbicide and placebo users. HIV incidence was 4.5 per 100 women years in the PRO 2000 group and 4.3 per 100 in the placebo group. Readers can find links to PDF files after the press release with additional information, including questions and answers about the trial, the results, quick facts, a technical fact sheet, and "Women's Voices," a sheet with study participants' perspectives of the trial.
Safety and efficacy studies are needed before microbicides can be tested in humans. This trial assessed how well tenofovir (TVF) vaginal gel or TVF with emtricitabine (FTC) protected 17 macaques from simian HIV (SIV) infection over a period of 20 weeks. The gel was administered twice weekly; simian-human immunodeficiency virus was administered 30 minutes after the gel. Five of six macaques in the placebo arm and both in the control arm (no intervention) became infected with SIV in an average of 2.5 weeks. None of the six macaques assigned active gel (TVF alone or TVF+FTC) became infected over 20 weeks (40 total SIV exposures). Furthermore, there was no evidence of damage to vaginal mucosa with use of either active microbicide. Despite study limitations, the authors conclude that this study suggests TFV gel can be used before intercourse to protect women from SIV without the need for daily use.
Researchers undertook this pilot study to identify ways to maximize adherence to diaphragms and microbicide gel ahead of a future study on microbicide effectiveness. Nearly 200 female sex workers (FSWs) in four cities in Madagascar were randomized into four groups: the gel microbicide Acidform plus diaphragm; placebo gel plus diaphragm; placebo gel; and Acidform gel. These were collapsed into two arms for data analysis: diaphragm plus gel or gel alone. Weekly follow-up meetings over one month collected information on product use and sexual practices with clients and regular partners. A statistically significant difference was found in adherence among women randomized to diaphragms (43 percent at first follow-up and 67 percent at last follow-up) compared to gel-only users (28 percent at first follow-up and 45 percent at last follow-up). Compliance improved over time in both groups. The authors believe this was due to the product protocol: diaphragm insertion was a daily event independent of sex, while the gel was to be used prior to coitus. Study findings will help develop counseling messages for future microbicides studies, helping women understand that discreet use is possible, but also indicating that some women choose to disclose product use to their partners.
HIV transmission during anal sex is higher than with vaginal sex due to physiologic factors. As such, a microbicide that can be safely used with anal intercourse could benefit heterosexual and homosexual couples alike. This study in 16 macaques assessed the effectiveness of a rectal tenofovir microbicide gel in preventing simian HIV (SIV) when administered up to two hours before and 15 minutes after rectal exposure to SIV. All placebo-arm macaques and two of the three receiving tenofovir after HIV exposure became infected with SIV. Eight of nine macaques assigned tenofovir before HIV exposure were completely or partially protected from SIV. The higher the tenofovir concentration in the blood 15 minutes after its administration, the greater the protection against SIV. Activated T-cells were found in the blood of the macaques protected from SIV, indicating that such exposure may be able to "prime and/or boost immune responses elicited with experimental vaccines." This study's results suggest that tenofovir rectal microbicide gel may have promise in humans.
This review of 118 studies--45 clinical and 73 preclinical--from a biomedical perspective assesses the state of microbicide development for HIV prevention. The authors first discuss the sexual HIV transmission pathways and how microbicides are being developed to address them. The different types of microbicides (e.g., viral entry inhibitors) are described, along with the current state of research for each type. The authors also discuss epidemiological and biological issues that make microbicide research challenging. Epidemiologic issues include HIV incidence, study populations, and discreet use of microbicides. Among biologic challenges are developing combination microbicides when each component must be first tested individually. The authors conclude that while the development of effective microbicides is difficult, the potential benefits are so great that they greatly outweigh any known risks--and possibly unforeseen risks as well.
Over 2,100 women in Lagos and Ibadan, Nigeria participated in a double-blind, randomized, placebo-controlled trial to assess the effectiveness of SAVVY vaginal microbicide gel in preventing HIV transmission. Participants filled out monthly questionnaires on sexual behavior, condom use, gel use, and any medical problems and were given 60 condoms and 60 vials of gel every month. Condom and gel use decreased over the 12-month study period over time, but was generally high. Adverse event rates were the same in both study arms, with no significant difference in chlamydia, bacterial vaginosis, candidiasis, or trichomoniasis rates between arms at the six-month follow-up visit. The study ended early due to lack of power to detect a statistically significant difference in HIV rates between study arms. While the ratio of HIV infections was higher in the SAVVY arm than placebo, the difference was not statistically significant. However, because of the study's low power, the results cannot conclusively support that SAVVY does not increase risk of HIV infection. This study highlights research challenges in measuring microbicide effectiveness.
This article describes the progress made in recent years to develop microbicides--gels, suppositories, or other topical formulations that prevent HIV--for rectal use. The design and results of early vaginal microbicide trials informed the research direction for evaluating potential rectal microbicide candidates, as did early acceptability studies among men who have sex with men, who are highly vulnerable to HIV because of the common practice of unprotected receptive anal intercourse. Most rectal microbicides in the pipeline have reached only the preclinical study stage. Only two products--UC781, a non-nucleoside reverse transcriptase inhibitor, and tenofovir, a nucleotide inhibitor--have reached the clinical study stage, although L'644, a promising fusion inhibitor, is now also being evaluated. Qualitative and clinical studies of acceptability for different rectal microbicide formulations have found gels to be most acceptable. Rectal safety became the focus of research soon after researchers found that vaginal microbicide candidates were not optimal for rectal use, causing mucosal damage in the rectum; recent research findings show that reducing the glycerin in the formulation may be less harmful. The author describes the preclinical evaluation of four rectal microbicide candidates that have undergone Phase I trials: HIVNET-008 (N9 gel), RMP-01 (UC781 gel), RMP-02/MTN-006 (tenofovir gel), and MTN-007 (tenofovir gel with reduced glycerin). In his conclusion, the author suggests that Phase I studies on rectal microbicides will continue to produce important data on safety, acceptability, and pharmacokinetics that will contribute to early product development.
The authors of this systematic review found that by the end of 2011, nine randomized controlled trials (RCTs) enrolling 31,941 sexually active women in 11 countries, with HIV incidence as the primary outcome, had demonstrated limited evidence that vaginal microbicides reduce acquisition of HIV and herpes simplex virus (HSV-2) infection in women. As a result, the authors do not recommend topical microbicides for HIV or STI prevention, but do suggest that development of new microbicides continue. Of the nine RCTs, the authors found that CAPRISA 004, a small proof-of-concept RCT enrolling 889 women, demonstrated that tenofovir--a nucleotide reverse transcriptase inhibitor--may reduce the risk of acquiring HIV and HSV-2. The authors are currently awaiting data from a second tenofovir trial enrolling 5,000 women, which was stopped early due to futility of results demonstrating a protective effect. According to the authors, other types of topical microbicides did not demonstrate a reduction in the risk of acquiring HIV or sexually transmitted infections (STIs), and none of the trials demonstrated that microbicides reduce the acquisition of other STIs, including gonorrhea, syphilis, genital warts, trichomoniasis, or human papillomavirus infection. The authors stress that if further studies demonstrate the effectiveness of tenofovir-based microbicides, efforts must be made to achieve rapid regulatory approval and create appropriate mechanisms for distribution.
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The excitement among the international microbicide development community resulting from the positive one-percent tenofovir trial results has given way to a sense of urgency--urgency to rapidly make available an approved, affordable, and easily obtainable microbicide to the world's women. This meeting brought together researchers, advocates, program implementers, funders, and regulatory agencies to identify concrete actions these actors can take to bring the one-percent tenofovir microbicide to women as quickly as possible. The report reviews discussions taking place during the meeting and presents the decisions made on what confirmatory studies should move forward, who will lead licensure efforts, and other necessary steps. Appendix 2 includes a summary of completed, ongoing, and planned microbicide clinical studies of one-percent tenofovir gel.
Ten married couples in Pune, India, participating in a microbicide clinical trial formed the basis for separate in-depth interviews on spousal communication about sex and sexual matters. Most couples reported nonverbal communication or using code words about sex because they often lived with extended families and usually did not sleep alone. Lack of knowledge about sex and sexuality as well as a lack of privacy limited couple communication. Five couples reported communicating about sex as a "side effect" of being in the clinical trial, despite this not being a part of the intervention. In addition to initiating discussions about HIV, these couples also reported appreciating having a space to talk about sex openly in the interviews. Many couples reported that their improved communication had a positive effect on their overall relationship. While this sample is not representative of Indian couples at large, it does indicate starting a dialogue about sex and sexuality encourages more communication about sex among the couple. Such communication is the crucial first step to reducing one's risk of HIV.
This report of a consultation attempts to clarify 2007 Joint U.N. Programme on HIV/AIDS and World Health Organization guidance on prevention standards in HIV prevention trials. As new research and evidence emerge about what is effective in preventing HIV, studies and trials will have to include these new technologies as standards of care in their work. Thus this report tries to translate ethical guidance into day-to-day research practice, taking into account that the guidelines were intentionally written to be flexible, given vastly differing circumstances, epidemics, and access to care. This report reviews the evidence on "what works," realities of implementing prevention trials, and the current standard of care for HIV prevention trials. It also presents points of agreement and disagreement among the participants of the consultation, and identifies needs for additional guidelines and criteria for those undertaking HIV prevention research.
This poster presentation explores women's attitudes to discreet use (use without their partner's knowledge) of a cervical barrier together with a microbicide. Among 83 married women in the trial, all had told their primary male partners about their use of the method by the end of the four-week trial. Focus group discussions among 41 women, however, indicated that they would use the barrier/microbicide without telling their primary partner if necessary. The rationale for telling their partners was to facilitate communication between the couple and avoid any problems should the use be found out. When probed about the reasons for discreet use, however, the women stated that they would indeed use a method that would protect them from HIV, given that most men are likely to have partners on the side. They felt it was important to safeguard their health, and therefore, that of their family. Telling partners about microbicide use may be a way to enlist male support for women's protection from HIV. Furthermore, the trial demonstrated to women that the method can indeed be used without their partners knowing about it.
This brief focuses on the potential of microbicides to integrate HIV prevention and the empowerment of sub-Saharan African women. The authors argue that empowering women can help offset the social, cultural, and economic factors that place women at disproportionate risk of acquiring HIV. Microbicides, they posit, can help become tools of women's empowerment if women's rights are at the forefront of microbicide development, strategy, and roll-out. The authors present four issues that must be addressed if microbicides are to become a tool for both HIV prevention and women's empowerment: effectiveness, availability, stigma, and partner communication.
Full and active engagement of the civil society in microbicide development can benefit everyone from researchers to the women who stand to benefit from microbicide use. A small working group identified seven priority gaps in microbicide research and development that civil society organizations could fill. The gaps were then broken down into concrete, actionable steps, resulting in 55 action steps for civil society, government/policymakers, researchers, and funders/sponsors. These "interlocking" steps show how each group's work complements and enhances the other groups' efforts. The report also highlights the importance of having an enabling environment to advance microbicide research, and what can be done to create such an environment.
Developing an effective microbicide is only the first step in saving women's lives. To truly be effective for HIV prevention, microbicides must be made widely available--entailing licensing, regulatory, and service delivery considerations--and be affordable and acceptable to all potential users. Researchers considered these factors when modeling how long it would take to see widespread microbicide use in southern India and South Africa. Stakeholder meetings reviewed women's reproductive health product introduction experiences and identified other key inputs for the models such as approval time and target audience penetration. Fully 120 scenarios were modeled and considered for India, while 156 were considered for South Africa. This paper describes the process and scenarios and juxtaposes the 10 most effective scenarios with the cost-effectiveness of each. While potential exists for microbicides to become another tool for HIV prevention, their widespread use can take significant time and resources.
Nearly 900 men who have sex with men in San Francisco participated in this random-digit dialing telephone survey about microbicides and Nonoxynol-9 (N-9). Nearly 4 of every 10 respondents sexually active in the last year reported unprotected receptive anal intercourse, while 45 percent reported unprotected insertive anal intercourse. Only 39 percent of the sample knew that N-9 could injure rectal tissue, thus potentially creating an entryway for HIV. N-9 use among these men in the last year was 26 percent. Men reporting recent unprotected anal intercourse were more likely to use N-9, which may indicate risk compensation or that these men are seeking alternatives to condom use for HIV prevention. Only 7 percent believed that N-9 could prevent HIV transmission. Although an effective microbicide was not on the market, 59 percent of the sample understood that a microbicide could reduce the risk of HIV. Interestingly, compared to uninfected men, those with HIV were more willing to use a microbicide that was less effective at preventing HIV than condoms.
Risk compensation theory posits that individuals will maintain a constant level of risk over time. As risk reduction behaviors are implemented (e.g., condom use), people will adjust other risky behaviors upward to compensate for the safety behaviors (e.g., have more sex partners), thus maintaining the same level of risk as before. This literature review examined whether study participants reported risk compensation behaviors when participating in trials of HIV vaccines, microbicides, male circumcision, and antiretroviral therapy (ART). Evidence was available for ART, HIV vaccines, and circumcision. Although limited, the few studies focusing on risk compensation among HIV vaccine trial participants found evidence of increased risky behaviors. A meta-analysis of highly active ART (HAART) also found more unprotected sex among HAART users who thought that HAART reduced the likelihood of HIV transmission. Similarly, circumcised men had riskier sexual behaviors (more partners and less condom use) compared to men who were not circumcised. The authors conclude that HIV prevention interventions must include risk compensation considerations into their programs.
This video was developed to help with microbicide advocacy efforts, particularly in countries and communities where such research is taking place. It answers basic questions about microbicides (what they are, how they work, how effective they are) as well as addresses HIV prevention and transmission. It also covers essential information about clinical trials. The video is available as a 100-second summary or as the full 20-minute version in English, French, kiSwahili, isiXhosa, and isiZulu.
This webpage contains brief descriptions of the Population Council's microbicide research projects taking place worldwide, with links to more in-depth information about each study. Older trials also have links to documents containing results, while ongoing trials provide descriptions of the work done to date. The research portfolio includes studies that assess ways to improve adherence to product use, different modes of microbicide delivery such as vaginal rings, and user acceptability research. Some novel approaches include computer-assisted self interviews being used in Malawi, South Africa, Uganda, the United States, Zambia, and Zimbabwe. This technique provides interviewees more privacy and confidentiality than answering aloud in face-to-face interviews.
The study sought to quantitatively and qualitatively explore the acceptability of a vaginal ring (VR) among sexually active women in Tanzania and South Africa. The ring could be used for the delivery of microbicides for HIV prevention if acceptability was high. The VR was provided to 158 women in the randomized trial. The ring had no active ingredient and was, therefore, a placebo. Participants were taught how to insert and remove the VR in the clinic. The women visited the clinic four times throughout the twelve-week trial for an exam and were asked about their comfort levels and experiences with the VR using a questionnaire. Focus group discussions and in-depth interviews were conducted with the women and their male partners, if the women gave the researchers permission. It was found that the majority of the women were able to successfully insert the VR (81 percent), and that retention over the twelve-week study period was high (97 percent). The women reported few concerns or problems about the VR during the study. The most frequently reported concern (20 percent at week 4) was that it would get lost in their body. The three most favorable characteristics of the VR at the 12-week point for the women was that it may be used someday to prevent HIV, does not interfere with sex, and that you can still use a condom with the VR. The three least liked characteristics of the VR were that it may get lost in the body, may come out during sex, and may change the feeling of sex for the partner. The VR was found to be highly acceptable for both the women and their partners in this study.
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This informative and engaging online course uses various media to teach people about microbicides, including readings, video clips, animated anatomical and biological graphics, and interactive quizzes. Eight modules cover what microbicides are, how they work, how they are developed, issues related to access and use, and how clinical trials test microbicide effectiveness. Users can take quizzes and tests to assess their knowledge and view videos of advocates answering common microbicide questions. The last module provides an overview of the current microbicide landscape, including mobilizing funding and community support for this method of HIV prevention. (Readers must register to access the full course; registration is free.)
This webpage contains the full study protocol for a clinical trial of tenofovir gel as a vaginal microbicide for preventing HIV. In addition to a detailed description of the study design, population, objectives, and regimens, information on eligibility, principal investigators, study sites, and collaborating institutions is available, including contact information. The page also provides links to publications related to this research and additional information on the study.
As advocates who have been working with members of civil society throughout the world on microbicides, the Global Campaign for Microbicides has extensive experience in communicating about microbicides to multiple audiences. This short brief clearly states seven talking points the organization follows and urges partners to follow. Among the points are the fact that microbicides are not a "magic bullet" and acknowledging that technological tools cannot replace the need for women's empowerment.
This short brief provides useful and practical information on how to organize a successful community forum on microbicides. Broken down into 10 steps, the following are included: consideration of partners to co-host, deciding on an agenda that the community would find interesting and engaging, logistics, budget, and spreading the word about the event. Readers can find excellent tips on engaging the media and following actionable steps to ensure ample participation from the local community and members of the media alike.
This document argues that in addition to the scientific research taking place on microbicide effectiveness, a parallel path must also take place among the international microbicide community: developing plans for microbicide access and use. Focusing on the five primary dimensions of access--acceptability and use; a supportive policy and social environment; availability; affordability; regulatory approval and licensing--each chapter lays out goals, objectives, and proposed activities that can help ensure that once an appropriate microbicide has been identified, structures are in place to rapidly make it affordable, accessible, and useable.
There is much potential for misunderstanding and controversy surrounding clinical trials. This handbook helps researchers, program managers, and others understand these communication challenges and guides readers on how to best share information with local communities and partners. It includes general communication guidelines, lessons learned from other country experiences, and multiple tools, such as risk assessment tools and sample templates that can sharpen staff skills in accurately answering questions about the research taking place. Sample communication plans as well as tips and techniques on communicating effectively in various fora are also included in the handbook.
The website offers the latest news on the past, present, or ongoing status of biomedical HIV prevention research studies. Readers can review summary tables from various HIV prevention clinical trials, search information on prevention trials, see what is new on the site each month, and review the user's guide for help in using the site. The site offers information about the following biomedical prevention trials: microbicides, pre-exposure prophylaxis, treatment as prevention, and vaccines.
HIV/AIDS: Microbicides
United States Agency for International Development. (2011).
This webpage provides information on U.S. Agency for International Development (USAID) activities related to microbicides, including the agenda, presentations, and meeting report of the high-level Microbicides Stakeholders Meeting in late 2010. Readers can find information on the agency's financial support for microbicides development, their stance on the results of the Centre for the AIDS Programme of Research in South Africa 004 trial, partnerships for microbicide support and development, as well as current USAID activities on microbicides research and development.
Regulatory Issues in Microbicide Development
Stone, A. (2009).
Because microbicides are a relatively new product, little guidance exists on the regulatory requirements needed at different stages of product testing and data necessary for licensure. To address this gap, the World Health Organization held six consultations in Europe, Africa, and Asia from 2002 to 2008. The first consultation drafted the minimal regulatory requirements for microbicide trials and eventual product licensing. Subsequent consultations opened a dialogue among in-country researchers, policymakers, and regulators about microbicide regulatory issues, with an aim to alleviate constraints to microbicide development. This report discusses the role of regulatory authorities in non-clinical and clinical microbicide studies, including safety, effectiveness, epidemiological principals, and pharmacology, as well as issues specific to microbicide use.
View Report (PDF, 578 KB)
Microbicide Research
CONRAD. (n.d.).
This webpage provides an overview of CONRAD's microbicide research activities, starting from some of the first microbicides developed in the 1990s to today's formulations that contain antiretroviral drugs. Readers can click on links to obtain more information on the development process for microbicides, as well as CONRAD's preclinical and clinical microbicide activities. In addition, information is available about their dual-protection microbicides that protect women from pregnancy in addition to sexually transmitted infections and/or HIV.
Global Advocacy for HIV Prevention. (n.d.).
This webpage provides readers with links to microbicide information, including introductory information to those that may not be familiar with the topic. A microbicide fact sheet is available in English, Spanish, French, Portuguese, and Thai for readers to download and disseminate. Readers can also follow a link to a collection of microbicide resources, including question and answer sheets and summaries of ongoing microbicide clinical trials. Readers can also link to a page that provides breakdown of clinical trials: ongoing trials, trial results, and planned trials.
Global Campaign for Microbicides
Global Campaign for Microbicides. (n.d.).
The Global Campaign for Microbicides promotes the rapid yet ethical development of and widespread access to HIV prevention options, especially for women. The organization collaborates with all sectors, from civil society to industry, and does not support any one product. This website includes information on microbicides, clinical trials, other prevention options such as female condoms and male circumcision, and more. Resources are available in English, French, Spanish, and Russian.
View Global Campaign for Microbicides Website
How Does It Work? Microbicides
Global Health Council. (n.d.).
This brief fact sheet clearly explains the biology of microbicides and how microbicides may work to help protect users from HIV, complete with references to selected research articles providing more detailed information. A useful graphic shows how a virus enters by disrupting the vaginal skin cell layers and also depicts how microbicides may be able to stop such disruption, and thus, viral entry.
International Partnership for Microbicides
International Partnership for Microbicides. (n.d.).
The International Partnership for Microbicides (IPM) is an organization founded as a product development partnership. Its mission is to speed the development of microbicides and other HIV prevention mechanisms for women in developing countries. Working with partners from academia to biotechnology companies to civil society organizations, IPM has several compounds in development and in various stages of clinical trials. Their website offers information on their work, different HIV prevention products for women, media resources, scientific articles, and other publications about microbicides.
International Rectal Microbicides Advocates
International Rectal Microbicides Advocates. (n.d.).
International Rectal Microbicides Advocates is an organization of individuals worldwide working to advance research and development of safe, effective rectal microbicides for men, women, and transgender individuals to use for HIV prevention. Materials that can be accessed on their website include information on the safety of lubricants for anal use, scientific articles, media stories, fact sheets, and more. This highly interactive site includes blogs and subscription to a moderated listserv. Links are available to sister websites for Nigeria and for Latin America and South America.
View International Rectal Microbicides Advocates Website
The Medium Matters: Applicators are Crucial to Success of Microbicides
PATH. (n.d.).
Something as simple as what kind of applicator is used in microbicides can have a significant impact on the product--for example, its cost, usability, and safety. PATH provides an interesting perspective on product development by describing the considerations behind applicator design, their choices between using single-use applicators and multiple-use applicators, and user-testing. Through this description, readers can see the balancing act required to be able to meet women's needs while also making a product safe and affordable. PATH is now working to obtain regulatory approval for microbicide applicators so that they can quickly be made available once a microbicide becomes available.
International Microbicide Conference
Sydney, Australia, 15-18 April 2012.
The biennial International Microbicides Conference, held in April 2012 in Sydney, Australia, focused on HIV prevention technologies, including the use of antiretroviral-based microbicides and pre-exposure prophylaxis (PrEP); adherence in clinical trials; innovative financing; dual prevention technologies; and new methods of preventing rectal transmission of HIV. In the keynote address, Dr. Salim Abdool Karim, co-principal investigator of the CAPRISA 004 trial, discussed implications and lessons learned nearly two years after the trial provided proof of concept for antiretroviral-based microbicides. In the opening plenary, Dr. Connie Celum of the University of Washington discussed the emerging evidence from recent oral and topical tenofovir-based PrEP trials that have demonstrated efficacy ranging from 39 to 75 percent. She emphasized the ongoing challenges of adherence, risk perception, and delivery of PrEP to most-at-risk populations. She urged researchers to continue to explore longer-acting products that are less adherence-dependent. To address the need for rectal microbicides, International Rectal Microbicide Advocates (IRMA) released a strategy document entitled The Map: Ensuring Africa's Place in Rectal Microbicide Research and Advocacy. Other presenters focused on a variety of topics, including multi-prevention technologies, access to microbicides, and recent findings from PrEP trials. The conference closed with a presentation from Gina Brown, U.S. National Institutes of Health, and Stephen Becker, Bill & Melinda Gates Foundation, who announced that the biennial microbicide conference will be replaced with a biennial global HIV prevention conference focusing on vaccines, microbicides, and oral PrEP.


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Classic Rattan Floor Cabinet
No longer available
Like the rattan furniture found in summer cottages of the Adirondack Mountains, this cabinet has relaxed charm. Thick rattan canes are steamed and bent by hand to create its frame, and the top and sides are covered with woven rattan.
16.5" wide x 12" deep x 30" high
Handcrafted of rattan, MDF and mahogany.
One fixed shelf.
Tempered-glass door.
Door is hinged on the right side.
Hand-applied lacquer finish.


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Barry Callebaut to open factory on U.S. West Coast
Zurich/American Canyon, CA (April 11, 2005) - Barry Callebaut, the world's leading manufacturer of cocoa and chocolate products, today announced the opening of a chocolate factory in American Canyon, Napa County, California, to better meet the needs of its rapidly growing customer base on the West Coast.
According to Barry Callebaut officials, the facility is creating 65 jobs, all of which have already been filled. The factory, which will initially have two production lines for the manufacturing of chocolate products designed for industrial and artisanal customers, covers a surface of 150,000 square feet that have been leased for 10 years in an existing building in the Green Island Industrial Park. It will be fully operational on August 1, 2005 and offer a maximum capacity of approx. 25,000 metric tonnes. Warehousing, distribution and customer service for all finished goods of the Barry Callebaut Group on the West Coast will be integrated in the American Canyon facility.
California is the biggest U.S. chocolate market. Barry Callebaut has grown its sales on the U.S. West Coast by 8-10% over the last two of years. "We decided on the American Canyon location partially because of its proximity to the Napa Valley and the Culinary Institute of America in St. Helena, and partially because the conversion of an existing building into a chocolate factory was much faster and efficient than building a factory from scratch," said Daniel Emond, head of Operations & Supply Chain, Barry Callebaut North America. "We're extremely pleased to be a part of all the exciting things happening here in Napa Valley, and we look forward to providing California chocolate lovers with the world's best chocolate," he added.
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Barry Callebaut (www.barry-callebaut.com):
With annual sales of more than CHF 4 billion (USD 3.5 billion) for fiscal year 2003/04, Zurich-based Barry Callebaut is the world's leading manufacturers of high-quality cocoa, chocolate and confectionery products - from the cocoa bean to the finished product on the store shelf. Barry Callebaut operates more than 30 production facilities in 22 countries and employs some 8,700 people. The company serves the entire food industry, from food manufacturers to artisanal users of chocolate (such as chocolatiers, pastry chefs or bakers), to global retailers. Barry Callebaut is the parent company of American Brach's Confections, Inc.
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for investors and financial analysts:
Dieter A. Enkelmann, CFO
Barry Callebaut AG
Phone: +41 43 204 04 20
Fax: +41 43 204 04 00
for media in Europe:
Gaby Tschofen, Spokesperson
Barry Callebaut AG Barry Callebaut AG
Phone: +41 43 204 04 60
Fax: +41 43 204 04 00
for media in North America:
Daniel Emond, Head of Production
Barry Callebaut North America
Phone: + 1 450 774 91 31


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Thurston Strainer
No longer available
Thick, substantial bases, braided detailing and shiny stainless steel give our Thurston Bar Tools distinguished presence. Shake your cocktail, then strain away ice and herbs with our handy Thurston Strainer.
3.5" wide x 1" deep x 8" long
Head is made of polished18/8 stainless steel.
Handle is nickel-plated brass.


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This course is intended for J.D. students and non-law students who want a basic general overview of the core subjects of intellectual property law: patents, copyrights, trade secrets, and trademarks. The course examines fundamental principles, their underlying policies, and how the laws inter-relate. Not open to students who have taken LAW P501 Intellectual Property Law Core, LAW A522 Copyrights, LAW A546 Patents, or LAW E588 Trademarks.
Last updated 8/10/2011 4:04:49 PM


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Nov, 2011
While automakers are doing their best to shorten their development cycles, they remain behind the curve in comparison with consumer electronics developers in general and the smartphone industry in particular. For quite some time now, automakers have been forced to guess which apps and interfaces will have the most appeal for prospective customers somewhere down the road. Though it is still in development, … Read More
HTML5, in-vehicle infotainment platform, cascading style sheets, XML, QNX Corp., real-time operating system


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Silver Pearl Chain Charm Necklace
$29 – $79
- Overview
Iridescent freshwater pearls are laced onto a shiny sterling silver chain to create a beautifully crafted necklace that's perfect for Mother's Day. Add a birthstone, initial or footprint pendant to create a gift to be cherished.
- Necklace: 16–18" long
- Cultured fresh water pearls are strung along a sterling silver chain.
- Wire-wrapped beaded chain with an S-hook clasp and a polished finish.
- Chain length is adjustable.
- Dimensions & Care
- Necklace: 16–18" long
- Initial Pendant: 0.5" diameter
- Foot Pendant: 0.5" diameter
- Bezel Charm: 0.25" diameter
- Sterling silver should be polished occasionally with a polishing cloth.
- Pearls can be cleaned with a mild soap, water and non abrasive cloth.
- Shipping Info
Please allow 5-7 business days for delivery. Delivery estimate includes monogrammed and gift-wrapped items.
International Customers: Items on this page are not eligible for Free Shipping. Please view our general guidelines for more information.
$35 – $79
- Free Shipping
Silver Birthstone Bezel Charm
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Silver Foot Charm
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Honorable Mention
Wooble is a simulacrum of pebbles realized through CNC milled 1" Appleply. It is a bathroom mat that stimulates the sense of touch, probing through the dull depository of skin on your sole.
Woobble uses CNC technology to achieve this complex effect without the need for tedious multi-pass surface milling. Designed with the CNC mill in mind, lines are directly drawn as a set of operations for the CNC mill rather than 3 dimensionally modeled. Complexity is achieved through selecting 3 different shaped tool bit, each specified at different stages of the operation.
Woobble surface geometry exposes the anatomy of 1" Appleply. The excavated curvature strips the white maple face to reveal the layers in between.