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Caroline's Parlor
Item# F1368
Caroline's family spends time together in their elegant parlor, featuring a built-in bookshelf, fireplace, and window overlooking the bay.
Learn more...
was: $300
you save: $135
Please Note:
- No price adjustments on previous purchases, returns or exchanges, or orders in progress that have not yet shipped. We reserve the right to limit order and item quantities.
Unfortunately, the offer will not be extended if you are unable to order due to technical issues.
- $20 shipping surcharge applies to all shipping methods.
- Due to its size, this item cannot be shipped USPS or to APO, FPO, the American Territories or Canada.
- Cannot be gift wrapped.
- Adult assembly required.
- Requires 3 AAA batteries, not included.
- American Girl's company name and address, plus the product description, will appear on the shipping box.
Product Description
This set features a fancy scene your girl can set up different ways for different playtimes:
- Three wooden walls that can be arranged any way your girl chooses
- A window seat that hinges open for storage space
- A paned window with a lacy curtain frames a view of Lake Ontario. She can slide in the illustrated window scene—different images on each side let her choose the season!
- The center wall features a mantle and a make-believe fireplace that really lights up
- A built-in wall shelf features pull-out drawers, plus a hutch that's perfect for displaying Caroline's treasures
- A model ship with real cloth sails
- A painted horse figurine and a metal candlestick
- A "sailor's valentine"—a two-piece wooden frame with a collection of faux shells inside
- An embroidered fireplace screen that she can adjust, just like the real thing! Caroline would have used it to soften the glow from the hearth and shield her face from the heat
- A framed mirror can be hung above the mantle for the finishing touch—or turned around to reveal a nautical painting!
Product Specifications
Finished dimensions:
W: 43 1/2" x H: 23 1/2" x D: 6 1/2" (US)
W: 110.5 cm x H: 59.7 cm x D: 16.5 cm (metric)


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Learn this important -- and potentially life-saving -- skill for cardiopulmonary resuscitation.
Project Heart Start Video
Learn to perform hands-only CPR through this free class.
About Cardiac Arrest
Sudden cardiac arrest kills more than 300,000 people in the United States every year, which accounts for about one in every six deaths nationwide.
Many of these deaths could have been prevented if those close by had been aware of a few simple, lifesaving steps.
The New CPR
If an adult suddenly collapses, the new CPR requires the rescuer to call 911 and then compress the chest at 100 compressions per minute.
The great thing about compression-only CPR is there is no more fumbling around trying to find a pulse, no rescue (mouth‐to‐mouth) breathing, and no complicated sequences to remember. It is easy to learn and, more importantly, easy to remember.
CPR Certification
The class doesn't provide CPR certification.
If certification is needed, the standard four-hour course is necessary.

subset: commoncrawl


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Please fill out all details in the following form and we will email a link to the image you have requested to the address you specify. You can include a message if you wish.
Don't worry, we won't store any information you put into this form.
Sending link to "Ermine Has Killed" by Leach, Sam


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Godzilla's Attack on IMAX® Boosts Its Box Office Power
By BloombergBusinessweek: Kyle Stock on May 19, 2014
For a 60-year-old mutant lizard, Godzilla still has plenty of blockbuster power.
The giant lizard's latest eponymous film garnered a better-than-expected $93 million in U.S. ticket sales in its opening weekend and another $103 million from 64 overseas markets, the best international debut so far this year. Godzilla crushed in the U.K. and Russia, while Mexico—normally a tiny movie market—ended up as the movie's third-biggest foreign box office, with $9 million in ticket sales.


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I ended up buying a half yard of two blacks one for the black border and one for the binding and that's all for this whole quilt. I love the prints in this collection and I like the pop of the black with the traditional Christmas colors.
Linking up to:


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- Overview
- Specs
- Reviews
Bern Watts Helmet
Have multiple impacts left you a few watts short of a light bulb? If so, then we have a bike helmet for you. ABS shell with EPS hard foam provides excellent head protection so you can mountain bike, BMX, skateboard and ski in confidence. 10 vents keep your head cool, integrated visor just looks cool and Sink Fit design feels as good as it looks. Rediscover those light bulb moments in the Watts helmet.- Ultra-thin ABS shell is approximately 20% lighter than last year's model
- EPS hard foam is specially engineered with expanded polystyrene for high-impact protection
- 10 ventilation holes provide balanced airflow
- Integrated visor offers eye protection and a cool look
- Sink Fit is Bern's trademark deep, low-profile fit and feel for balanced protection
- Adjustable chin strap for a personalized fit
- Snap-in clip system accommodates a variety of interchangeable cold and warm weather liners for all-season use (liners not included)
- EPS complies with ASTM F 2040 and EN 1077B for snow and ski, CPSC and EN1078 for bike and skate
Bern Watts Helmet
- colors:
- Matte Grey/Neon Green (Matte Grey/Neon Green)
- retention system:
- Adjustable Chin Strap
- sizing:
- vents:
- 10
- weight:
- 448g
- rating:
- 5


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Doll Bunny Easter Basket
No longer available
- Overview
A fluffy Easter Bunny is the perfect companion for a successful egg hunt. He's sure to know where all the goodies are hidden!
- 2" opening, 2.5" high
- Polyester felt with sherpa exterior.
- Cotton gingham lining.
- Designed to fit any of our Pottery Barn Kids dolls.
- Dimensions & Care
- Surface washable with warm water and mild soap.
- Shipping Info
- Please allow 5-7 business days for delivery. Delivery estimate includes monogrammed and gift-wrapped items.


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we used for our valentines a few years ago.
A couple other thoughts.
I'm so excited the Olympics are here! I already got teary 5 minutes into the first montage. I've been an Olympic junkie since Sarajevo when I was about 9. And then they came to my own back yard (almost literally - the Sale Lake Olympic stadium is within walking distance of where I grew-up.) Only I had a 3-year-old and a nursing baby at the time, so I didn't do a lot of Olympic spectating other than from my couch like most of the rest of the world. But I'll tell you this - that Olympic spirit is real. During the time that Olympic flame was lit, there was an amazing feeling in Utah and as soon as that flame went out, it left. (Can anyone else attest to this?) Really awesome. Getting to taste that spirit was a sweet experience. Enjoy it Vancouverites!


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Sergio Perez is backing Sauber to claim a race victory this season, confident they will build on last year's success.
Sauber had a stellar 2012 Championship with four podium finishes in what was their best season since Peter Sauber bought his team back from BMW.
Two of those were runner-up results with Perez losing out to Fernando Alonso in Malaysia and later coming second to Lewis Hamilton in Italy.
His results earned the Mexican driver a race-seat with McLaren for this year's Championship.
And although Perez has moved on, the 22-year-old is backing his former team to taste success in 2013, confident the ingredients are in place for Sauber to win.
"Sauber will be strong again, I am firmly convinced," the 22-year-old told Speed Week magazine.
"The rules are fairly stable, the Swiss team has understood its car well, so why should they be worse than 2012?
"I even think there could be World Championship events they are capable of winning.
"Sauber has done a lot for me, so I would be happy for the team to do well more than any other team - with the exception of McLaren of course!"
Sauber will have an all-new line-up for this season with Nico Hulkenberg teaming up with rookie racer Esteban Gutierrez.


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By Ken Satterfield
Summer is almost upon us. Even if you are not in school, you may be making plans for vacations, reunions or other special events in the next few months.
What about your church? Although attendance often dips, summer is also an exciting time for outreach and ministry. Vacation Bible School, mission trips, anniversaries and special community events may be on your congregation's calendar in the next few months.
Sometimes event publicity is an afterthought, rather than an initial part of the planning process. Reasons can range from 'If we plan it, they will come" to "If it involves God, He'll handle the details" to "Nobody wants to hear about what we're doing." In fact, publicity should be critical.
Hear are a few tips to encourage your church to maximize opportunities to get the word out:
What is the hook? Not everything may be newsworthy, but often a story becomes more interesting when you consider the Golden Rule of publicity: "Tell unto others, as you would want them to tell unto you." In other words, identify with their interests.
A bake sale or Vacation Bible School may not attract a lot of attention because many churches are having them. However, what if your VBS featured a project to help the local homeless ministry? Or if the sale allowed someone with a rare disease to receive treatment? Twists like these move a listener's interest from "Oh" to "Oh!" Newspapers and local newscasts like to be able to report an interesting and engaging story.
Develop your community options. Brainstorm a list of ways you could let people in your area know about what's coming up. TV, radio, local cable access announcements, flyers, libraries, community and media Web sites, your church sign and many other possibilities exist. Remember that word-of-mouth is often the most effective form of communication.
Develop relationships. Get to know contact people at newspapers, radio stations, television outlets, community organizations and other places you have listed. If you stay in touch and share newsworthy information, they will grow to welcome your calls and e-mail. Also, make sure to learn their routines and avoid hectic times in their production schedules.
Develop your materials. If you don't have time to write up a good press release or put together an attractive flyer, the recipient probably won't find time to look at it, either. Remember the basic who, what, when, where, why and how in your materials. You can find a more thorough guide to press releases at guide.gospelcom.net/resources/writing-pressreleases.php. Depending on the event, local stations may consider airing a Public Service Announcement (PSA) or including it in their community calendar. Don't confuse your advance publicity with necessary advertising and/or direct marketing, because your recipient won't, either!


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The B.A. chemistry program provides you with a sound foundation in the basic areas of inorganic, organic, analytical, and physical chemistry. The core of 41 chemistry credits (including a required research experience, advanced writing and chemistry seminar), combined with 8 credits each of mathematics and physics prepares you for your future as a professional in the field of chemistry. Further, the B.A. allows for 30 to 40 credits of elective work, which can be used to complete a major or minor in a second field other than chemistry, as dictated by their personal goals. Environmental chemistry is among the more popular secondary areas of specialization. Students may also select courses as pre-professional requirements for graduate study in medicine, veterinary medicine and dentistry.
Elective hours may be selected through advisement to fulfill the American Chemical Society's additional requirements for certification.
If you would like more information about chemistry at SUNY Plattsburgh, please contact:
Linda Luck, Chairperson
Office: Hudson Hall 319B
Phone: (518) 564-4119
Email: firstname.lastname@example.com


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quote:playing pvp it drops to 5-10 fps
quote:You could upgrade to a Z77 mobo for around $150 and buy an i5 3570K for 200 and with that GPU and ram run pretty much anything flawlessly.
quote: that GPU and ram run pretty much anything flawlessly.
quote:Flawlessly... Eh. Games like GW2, yes
quote:f I were him, and wanted to upgrade for cheap, I would use that 7750 along side the new AMD APU chips with this mobo. It will allow you to run eyefinity and it's pretty much like having two 7750s crossfired.
quote:I was going to suggest the same hybrid xfire
quote:Are these things easy for me to install or will I need to have to bring it somewhere?


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Drug Notes
UPMC Patient Education Materials
Calculators and Assessment Tools
Anatomy Navigator
Conditions Navigator
Mitral regurgitation is a disorder in which the mitral valve on the left side of the heart does not close properly.
Regurgitation means leaking from a valve that does not close all the way.
Mitral valve regurgitation; Mitral valve insufficiency
Mitral regurgitation is the most common type of heart valve disorder.
Blood that flows between different chambers of your heart must flow through a valve. The valve between the two chambers on the left side of your heart is called the mitral valve.
When the mitral valve doesn't close all the way, blood flows backward into the upper heart chamber (atrium) from the lower chamber as it contracts. This cuts down on the amount of blood that flows to the rest of the body. As a result, the heart may try to pump harder. This may lead to congestive heart failure.
Mitral regurgitation may begin suddenly. This often occurs after a heart attack. When the regurgitation does not go away, it becomes long-term (chronic).
Many other diseases or problems can weaken or damage the valve or the heart tissue around the valve. You are at risk for mitral valve regurgitation if you have:
Another important risk factor for tricuspid regurgitation is past use of a diet pill called "Fen-Phen" (fenfluramine and phentermine) or dexfenfluramine. The drug was removed from the market by the U.S. Food and Drug Administration (FDA) in 1997 because of safety concerns.
Symptoms may begin suddenly if:
There are often no symptoms. When symptoms occur, they often develop gradually, and may include:
When listening to your heart and lungs, the health care provider may detect:
The physical exam may also reveal:
The following tests may be done to look at the heart valve structure and function:
Cardiac catheterization may be done if heart function becomes worse.
Treatment will depend on what symptoms you have, what condition caused the mitral valve regurgitation, and how well the heart is working.
People with high blood pressure or a weakened heart muscle may be given medicines to reduce the strain on the heart and ease symptoms.
The following drugs may be prescribed when mitral regurgitation symptoms get worse:
A low-sodium diet may be helpful. You may need to limit your activity if symptoms develop.
Once the diagnosis is made, you should visit your health care provider regularly to track your symptoms and heart function.
You may need surgery to repair or replace the valve if:
The outcome varies. Most of the time the condition is mild, so no therapy or restriction is needed. Symptoms can usually be controlled with medicine.
Problems that may develop include:
Call your health care provider if symptoms get worse or do not improve with treatment.
Also call your health care provider if you are being treated for this condition and develop signs of infection, which include:
People with abnormal or damaged heart valves are at risk for an infection called endocarditis. Anything that causes bacteria to get into your bloodstream can lead to this infection. Steps to avoid this problem include:
Otto CM, Bonow RO. Valvular heart disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 66.
Nishimura. RA, Otto CM, Bownow RO et al. 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Thorac Cardiovasc Surg. 2014;148(1):e1-e132.
Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.
UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, gender identity, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.
Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.
For UPMC Mercy Patients: As a Catholic hospital, UPMC Mercy abides by the Ethical and Religious Directives for Catholic Health Care Services, as determined by the United States Conference of Catholic Bishops. As such, UPMC Mercy neither endorses nor provides medical practices and/or procedures that contradict the moral teachings of the Roman Catholic Church.
© UPMC Pittsburgh, PA, USA UPMC.com


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quote: I'm thinking about getting a job in Alaska for the summer if I don't like any of my options for when I graduate in March. Any good suggestions for some good paying summer jobs up there that doesn't include commercial fishing? I'm thinking the tourist business gets pretty popular in the summer up there.
quote:Email me email@example.com I can give you some leads.
quote:Love your underwater pics, ScubaBlake. Except the fire coral one. I sat on a piece of that shite in Jamaica. My arse was on fire for two days. That shite hurts!!


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Email UKClimbing.com User
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Please email the UKClimbing.com editor with any comments about this feature.
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Drug Notes
UPMC Patient Education Materials
Calculators and Assessment Tools
Anatomy Navigator
Conditions Navigator
Sheehan syndrome is a condition that can occur in a woman who bleeds severely during childbirth. Sheehan syndrome is a type of hypopituitarism .
Postpartum hypopituitarism; Postpartum pituitary insufficiency; Hypopituitarism Syndrome
Severe bleeding during childbirth can result in tissue death in the pituitary gland. This causes the gland to lose its ability to work properly.
The pituitary gland is at the base of the brain. It makes hormones that stimulate growth, production of breast milk, reproductive functions, the thyroid, and the adrenal glands. A lack of these hormones can lead to a variety of symptoms.
Conditions that increase the risk of bleeding during childbirth and Sheehan syndrome include multiple pregnancy (twins or triplets) and problems with the placenta. The placenta is the organ that develops during pregnancy to feed the fetus.
Sheehan syndrome is very rare.
Symptoms of Sheehan syndrome may include:
Note: Other than not being able to breast feed, symptoms may not develop for several years after the delivery.
Treatment involves estrogen and progesterone hormone replacement therapy. These hormones must be taken at least until the normal age of menopause. Thyroid and adrenal hormones must also be taken. These will be needed for the rest of your life.
The outlook with early diagnosis and treatment is excellent.
This condition can be life threatening if not treated.
Extreme bleeding during childbirth can often be prevented by proper medical care. Otherwise, Sheehan syndrome is not preventable.
Cunningham FG, Leveno KL, Bloom SL, et al . Obstetrical hemorrhage. In: Cunnigham FG, Leveno KL, Bloom SL, et al, eds. Williams Obstetrics. 23rd ed. New York, NY; McGraw-Hill; 2009:chap 35.
Malee MP. Pituitary and adrenal disorders in pregnancy. In: Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics - Normal and Problem Pregnancies. 6th ed. Philadelphia, PA: Elsevier Mosby; 2012:chap 41.
Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Bellevue, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.
For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.
UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, gender identity, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.
Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.
For UPMC Mercy Patients: As a Catholic hospital, UPMC Mercy abides by the Ethical and Religious Directives for Catholic Health Care Services, as determined by the United States Conference of Catholic Bishops. As such, UPMC Mercy neither endorses nor provides medical practices and/or procedures that contradict the moral teachings of the Roman Catholic Church.
© UPMC Pittsburgh, PA, USA UPMC.com


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Frequently asked questions
- What is California's stem cell agency, the California Institute for Regenerative Medicine (CIRM)
- What does the stem cell agency do?
- How much money have you spent so far?
- What has the agency funded?
- Why did the agency fund new buildings?
- Has the agency made money for the state?
- What diseases are you working on?
- When will there be cures?
- Who decides what the agency funds?
- What happens when the funding runs out?
- What organizations are eligible to receive funding?
- Can the funding be used for human reproductive cloning?
- Does stem cell research harm human embryos?
- Shouldn't private industry fund stem cell research?
- Doesn't the NIH fund stem cell research?
- How can I stay up to date about the agency's activities?
- Can I donate to California's stem cell agency?
What is the stem cell agency, the California Institute for Regenerative Medicine (CIRM)?
California's stem cell agency was created by the voters of California in 2004 when they passed Proposition 71, which authorized $3 billion in funding for stem cell research in California. The agency funds stem cell research at institutions throughout California with the goal of developing new therapies for deadly diseases and disorders. Here is the text of Proposition 71.
What does the stem cell agency do?
The agency uses money from bond sales to advance stem cell research in California. The agency doesn't carry out research itself. Instead, the agency solicits research proposals and funds research, training and new research space throughout the state. A list of all our funded awards is available here.
The ultimate goal of our programs is to accelerate the pace of stem cell research in California toward new treatments for life threatening diseases and debilitating disorders like spinal cord injuries, often things for which there are no treatments today. By promoting the research and encouraging the growth of the stem cell biotechnology sector the agency has helped attract the best scientists to the state and established California as a global leader in stem cell research.
You can learn more about stem cell research and how it can lead to new disease therapies through our Stem Cell Basics Primer.
How much money have you spent so far?
You can see how much money California's stem cell agency has committed and spent at any time on our funding commitments page. The amount of money we've committed is the amount of money that our governing board has agreed to spend on all awards. However, most of those awards are for research that takes place over the course of several years. We give out funds incrementally rather than in one lump sum at the beginning of the award. That allows us to monitor the projects and terminate funding if the researchers aren't meeting their goals, thereby saving money for the state. That's why on the funding commitments page the amount of money we've actually spent to-date is just a fraction of the amount we've committed to spend on the full term of the awards.
On the funding commitments page, we also show the amount of money that we expect to spend on a given award by the end of its funding period. This number is usually less than the amount of money originally approved by the governing board. That's because we work with grantees to bring costs down where possible, lowering the amount of money it takes to carry out the proposed research.
What has the agency funded?
We fund in three general areas: research, training and facilities. This page of charts shows how our funds have been allocated. When we started in 2004, there were few facilities in California where scientists could work with all types of stem cells, and few scientists had access to labs that contained all the equipment needed to do this specialized work. One of our earliest rounds of funding went to build lab spaces that could be shared by researchers within the institution and by visiting scientists. Those spaces are also used to train scientists how to work with stem cells.
We considered training to be a major need to build the field and create the next generation of stem cell scientists. New therapies won't happen without people trained to work with stem cells and who have both the technical skills and the equipment they need to carry out groundbreaking research. We now have programs to train high school students, college students, graduate students and early career scientists.
Most of our funding goes to the research itself. There, too, we don't put all of our money in one area. In the early years, because this is such a new area of research, much of the funding was focused on basic science, to help develop a deeper understanding of stem cells and how they worked. More recently we have been focusing on trying to move the most promising ideas that came out of that earlier funding into clinical trials in people. On our Progress Toward Therapies page we have a chart showing how CIRM's funding has changed over time, as more good ideas from the lab start being ready to test in animals and then in people.
Why did the agency fund new buildings?
When California's stem cell agency started in 2004, little research space existed where scientists could work with all types of stem cells and that contained all the equipment needed to work with the cells and develop new therapies. Stem cell scientists were also spread across research campuses, limiting interactions and slowing the spread of ideas. One of the greatest needs identified for the development of new stem cell therapies was laboratory space for these scientists to work and exchange ideas.
The agency provided $271 million toward 12 buildings throughout the state, requiring the institutions to provide the remaining $884 million to construct and furnish the buildings. That money largely came from donations from individuals or foundations who were inspired by the agency's initial commitment to contribute toward the project. This public/private partnership created much needed work for the construction industry and new, full-time jobs for researchers and others staff. Here we have more information about those facilities and the major donors to each.
Has the agency made any money for the state?
The agency's grants create jobs in California and have expanded the biotechnology industry in the state. Our grants for new buildings also created construction jobs at a time when the state desperately needed them.
An independent analysis found that the agency's major facilities program alone created 13,000 job-years (this is economist-speak for creating the equivalent of 13,000 jobs that last one year, or 6,500 jobs that last two years) and brought in $100 million in tax revenue. Our other programs create research positions, and positions associated with a growing biotech industry in the state. More broadly, by 2014 our programs are expected to have created more than 38,000 years of jobs and generated $285 million in tax revenue in California.
The tax revenue that results from the agency's funding goes directly into the state's general fund, where it pays for the interest on our bonds as well as other programs in the state.
In the future, as our funding leads to the development of new therapies, a portion of the profits from the sale of those therapies will also be returned to the state. And of course because these therapies are treating diseases that currently have no effective remedy we will also be reducing the health care burden on California, reducing medical spending and improving the quality of life for people in the state.
What diseases are you working on?
There are a wide variety of diseases that CIRM-funded scientists are working on, including some of the biggest killers of Americans such as heart disease, stroke, cancer, diabetes, Alzheimer's, and Parkinson's disease. We are also working on diseases that affect far fewer people but are no less deadly or devastating, things like Huntington's disease, sickle cell disease, autism, muscular dystrophy and Lou Gehrig's disease (ALS).
You can read our disease pages for more information about how stem cells can benefit different diseases and see a list of awards tackling that disease area. We also have a list of all CIRM awards that you can filter by disease area.
When will there be cures?
The usual path from a scientific discovery to a new cure is on the order of decades or longer. James Thompson and his team generated human embryonic stem cells in 1998 and the first trial based on those cells started in 2010—a remarkably fast timeline for new therapies. The reprogrammed iPS cells that earned Shinya Yamanaka a Nobel Prize in 2012 were only discovered in 2007, and are expected to be entering clinical trials in the next few years. Similarly, trials based on work by CIRM-funded teams using tissue-specific adult cells are already underway and, if those trials are successful, will reach patients in a matter of years.
Research funded by the agency is moving toward patients at an accelerated pace because CIRM works closely with our teams to help them overcome the many obstacles they face in moving their research from the lab to the clinic – these obstacles include scientific and technical challenges as well as regulatory hurdles and even matters of reimbursement, namely who will pay for the treatment once approved. (This pages have more information about how we are smoothing the path to new therapies.) We provide a continuous source of funding so that promising therapies don't languish while researchers seek out new funding sources. We also work with the FDA, which regulates clinical trials, to help our grantees understand the regulations and succeed at bringing new therapies to patients.
We at California's stem cell agency also have friends and family members with incurable diseases and like everyone else are impatient to see new therapies approved and ready for use in patients. However, shortcuts in the path to new therapies can result in treatments that harm patients rather than helping them. That's why we are working to remove the barriers that slow research without compromising safety.
Who decides what the agency funds?
The agency's funding happens in several steps. First, our science staff decides what type of funding is most likely to help propel new therapies. We fund research through rounds of funding, each of which is aimed at a specific goal. For example, we have rounds of funding intended to entice researchers into the field of stem cell research, to fund basic discoveries with stem cells, to take basic discoveries and develop them into therapies in people, and to begin funding clinical trials.
Once the agency puts out a request for applications, or RFA, researchers throughout California have time to submit an application. (Here is a list of all RFAs.)
The agency doesn't work alone to decide which applications to fund. We have an international group of independent experts in stem cell research, therapy development and from the biotech industry who review the applications and make recommendations to our governing board. All these experts are from outside of California. (Here is more information about this grants working group.) The grants working group makes recommendations to our governing board regarding which applications to fund. Those recommendations are available for every application on our page listing RFAs by following the links titled "Summaries of review reports" under each RFA.
Our governing board then reviews those recommendations and votes on which applications to fund. All of those awards are listed on our website. Governing board members from a institutions that are eligible for CIRM funding are not able to vote on any funding decisions.
Usually the governing board follows the grants review group's recommendations, but in some cases a board member will suggest funding an application that received a lower score. This process gives patient advocates a voice in the process of deciding which research to fund, and provides a way of funding research in disease areas that aren't being addressed by pharmaceutical companies. Proposition 71 was written in a way that makes it possible for patient advocates to have a voice in deciding which disease areas should be the focus of state-funded research.
Proposition 71 gave you $3 billion over ten years. What happens when the money runs out?
Right now the agency is exploring a number of different options to try and ensure that we are able to continue funding stem cell research after the money allocated to us by Proposition 71 runs out. Those include raising funds from philanthropic sources and partnering with industry to enable us to continue our mission.
SB1064 required CIRM to create a transition plan for when our funds run out. That plan is posted on our website.
What organizations are eligible to receive funding?
Any California-based research institution or company may apply for funding. This page contains a complete list of all organizations that have received funding. We also provide a searchable list of all stem cell grants awarded by CIRM.
Organizations that only have facilities outside of California are not eligible for CIRM funding. However, the agency does have collaborative funding partnerships with other funding agencies—international countries and states as well as U.S. states and foundations. Researchers in those states or countries apply with California investigators for CIRM awards, with the other funding agency paying for the research that takes place outside of California. We have more about those partnerships here.
Can the funding be used to fund research on human reproductive cloning?
No. Reproductive cloning is specifically prohibited under Proposition 71 and under California law.
Does stem cell research harm human embryos?
Almost all human embryonic stem cell lines come from four to five day old embryos left over from in vitro fertilization (IVF). In in vitro fertilization, researchers mix a man's sperm and a woman's eggs together in a lab dish. Some of those eggs become fertilized and begin developing. At about five days the egg has divided to become a hollow ball of roughly 100 cells called a blastocyst, which is smaller than the size of the dot over an "i". It is these very early embryos that are implanted into the woman in the hopes that she becomes pregnant.
Each cycle of IVF can produce many blastocysts, some of which are implanted into the woman and the rest are stored in the IVF clinic freezer. After a couple has completed their family, they must decide what to do with any remaining embryos. They can continue paying to store the embryos or they can defrost the embryos, which destroys them. Some couples may choose to donate the embryos for adoption, though that option is not commonly taken. In some states, couples can also choose to donate the frozen embryos for research. These donated embryos are the source of human embryonic stem cell lines. Creating those lines does destroy that early embryo.
Some embryonic stem cell lines also come from embryos that a couple has chosen not to implant because they carry genetic mutations like the ones that cause cystic fibrosis or Tay Sachs disease. These are discovered through routine genetic testing prior to implantation. Still other embryos might be malformed in some way that causes them to be rejected for implantation into the mother. These embryos with genetic defects or malformations would have been discarded if the couple had not chosen to donate them to stem cell research. These cell lines are extremely useful for studying the diseases that arise from those mutations.
Why are we paying for stem cell research, shouldn't that be a job for private industry?
State and national governments have a long history of being involved in the kind of pioneering research that private industry is unable or unwilling to do. Private industry has to focus on the financial return, making them unlikely to take risks on projects with no guarantee of success. Government agencies can fund research with a focus on benefits to the public rather than on making money. This difference in focus gives government agencies the ability to fund projects that could have a big impact on human health but with little guarantee of financial return, at least in the short term.
At the Federal level the government's support was vital to the success of the Human Genome Project, and funding from the NIH led to the development of 15 of the top 21 drugs introduced between 1965 and 1992.
Private industry tends to focus on projects that are in later stages of development. Without funding for the earliest stages of discovery there will be no stem cell therapies making it into those later stages where private industry becomes involved. We have more information about the therapy development pipeline on this page.
Scientists have referred to the stage right before industry becomes interested as the "Valley of Death". It's an area where promising therapies often languish, because there isn't enough federal funding to push the projects through to the later stages. CIRM is very focused on funding the early research that leads to therapy ideas, and we fund heavily in the Valley of Death, helping to keep good projects moving toward the clinic. We also work with industry to fund later stages of verifying those therapies and beginning clinical trials in people.
Doesn't the NIH fund stem cell research?
The NIH and other federal agencies do fund stem cell research and play a vital role in driving scientific discovery. However, they have very broad research interests. With the agency's focus on stem cell research we are able to work closely with academics and industry to craft our funding programs in a way that accelerates the field. Our programs are timed so that researchers with successful projects will have continuous funding from the basic laboratory research through beginning clinical trials. The NIH tends to focus more heavily on early stage research, leaving scientist with promising ideas having to pause their research and look for new sources of funding as the projects get closer to clinical trials.
CIRM also works closely with our research teams to help them navigate regulations leading up to clinical trials, and to find industry partners to help fund the later stage research. This ability to focus on accelerating stem cell research toward clinical trials is only possible for an agency with CIRM's mission.
The NIH is also restricted in the types of research it can fund. Unlike the NIH, CIRM funds the creation of new stem cell lines, lines that have been critical to the success of some research programs.
How can I stay up to date about the agency's activities?
We have several ways of keeping people up to date on our research progress.
- Sign up for our email lists. We have four different lists that provide people with information about CIRM news, new funding opportunities, and opportunities to attend public meetings.
- Read our blog. We report on progress by CIRM grantees and update readers on the field of stem cell research.
- Follow us on social media. We have active Facebook, Twitter, YouTube and Flickr channels
Can I donate to California's stem cell agency?
Under Proposition 71, CIRM can accept donations of "additional revenue and real and personal property [including cash], including, but not limited to gifts, royalties, interest, and appropriations that may be used to supplement annual research grant funding and the operations of the institute." To implement this section, the ICOC has adopted a policy and procedure on the acceptance of donated real and personally property.
That policy is available here: Gift policy [pdf]
If you have questions, please contact CIRM.


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Ombre Stripe Elastic Waist Dress
Ombre Stripe Elastic Waist Dress
$64 .88
 Ombre stripes lend statement making impact to this high-def design, flaunting a marvelously modern touch: an easygoing elasticized waist. Ballet neck. Sleeveless. Grosgrain trim at neckline. Solid elasticized waist with gathered detail. Keyhole detail at back neck with button closure. Lined. 19 1/2" from waistband.


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GameBoy Advance
Game Questions & Answers (Q&A) service lets you ask questions about video games for game consoles or PC games. So ask your Lizzie McGuire 2: Lizzie's Diaries question for GameBoy Advance and get answers from real gamers or answer questions and share your insights and experience with the rest of the gaming community.
Boxshot / Details
- Developer: Artificial Mind and Movement
- Publisher: Disney Interactive Studios
- Genre: Action Adventure
- Release Date: Oct 18, 2004
- ESRB: Everyone
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Beach level lizzie
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From: Karolina
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Posted On: 06-14-2012
Posted On: 06-14-2012
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Map Triptych
No longer available
The triptych – a work of art divided into three sections – has been a popular format for paintings and stained glass works since the Middle Ages. We've drawn from this form to capture a sense of wanderlust with this screen-printed map.
9.25" wide x 16.5" high
Screen-printed 126-gram paper.
Copper frame.
Glass front.
Attached rope for hanging.


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Product Description
Available while supplies last.
Rodney uses visual cues from vintage advertising and Americana to convey the bygone era of optimism, one where advertising was meant to inspire. Rodney's art is an open journal of his personal path of belief and optimism. It illustrates the moment of enlightenment that we all seek. One can see the methodology behind his thinking and experience, voyeuristically, his personal growth by looking at his art.
Materials: | Artist Grade Canvas and Wood | |
Listing: | Made in USA | |
Canvas Art Subject | Novelty |
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Seawolf Volleyball Camps
University of Alaska Anchorage head volleyball coach Chris Green and his staff conduct several summer camps each summer.
Click here for complete camp details / CLICK TO REGISTER
UAA Basketball Skills Camp
The UAA Skills Camp is a great chance for players to enhance their overall basketball abilities. The camp focuses on developing the campers' offensive and defensive capabilities. Focus areas will be shooting technique, ball handling, defensive positioning & movements, and scoring moves. Campers will learn new drills and techniques from current college players and coaches which can be used for continued improvement year-round! Most importantly the camp is a high-energy, active way for kids to have fun while improving their basketball skills. MORE INFO / CLICK TO REGISTER
Kendall Jump Shot Basketball Camp
University of Alaska Anchorage head men's basketball coach Rusty Osborne heads up the annual Kendall Jump Shot Basketball Camp each summer at Sullivan Arena. The camp is open to boys and girls ages 6 to 16, and features a Combo Camp as well as an Elite Camp. There are two week-long sessions to choose from. The camp features instruction from Coach Osborne, UAA Assistant Coach Cameron Turner, plus other Seawolf coaches and players, area high school coaches and guests. More information is available by calling the Sullivan Arena at 279-0618 or visiting sullivanarena.com.
Seawolf Hockey Camp
University of Alaska Anchorage head coach Matt Thomas will host a hockey camp, July 7-11 at the Wells Fargo Sports Complex. Age groups 5-7, 8-10 and 11-13 as well as an elite and goalie camp will be offered. For more information and to register, please contact Steve Thompson at email@example.com.


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Limited Edition Götz Doll Carmen
No longer available
- Overview
Designed by the expert doll makers at Götz, our collectible-quality dolls pay homage to countries and cultures around the world. Carmen from Mexico wears a pretty yellow dress with floral accents, and comes with a plush puppy friend and a special story about her family and heritage.
- 18" high
- Carmen wears a colorful dress and headband and comes with a stuffed dog.
- Face has blushed cheeks, life-like eyelashes and eyes that close.
- The doll has long hair that can be washed, styled and brushed.
- The doll's arms and legs can be moved up and down.
- Ages 3 and up.
- Dimensions & Care
- Place doll into pillowcase.
- Machine wash in cold water, delicate cycle.
- Lay on belly to air dry.
- Machine wash clothes separately in cold water, delicate cycle.
- Shipping Info
- Please allow 5-7 business days for delivery. Delivery estimate includes monogrammed and gift-wrapped items.


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Savannah Removable Wallpaper
No longer available
- Overview
Bring the pretty, fashion-forward look of wallpaper to your child's room without mess or fuss.
- 18" wide x 10.5' long
- Easy sure-strip application creates the look of a custom mural.
- Dip pre-pasted strips in warm water and mount to the wall.
- Remove in one piece and without any surface damage.
- For best results, mount to a smooth surface.
- Sold individually.
- Dimensions & Care
- Overall: 18" wide x 10.5' long
- Repeat: 18x18"
- Wipe using a clean damp cloth with cold water and a mild detergent.
- Shipping Info
Please allow 5-7 business days for delivery. Delivery estimate includes monogrammed and gift-wrapped items.


text: 5 Great introduction to blu-raybadgereaux | 05/07/2012 | See all badgereaux's reviews (1)We've always hung back on buying a blu-ray player until the price came down - which is now. This is a really good value little box.A lot of blu-ray discs come with a warning that they can take 3 minutes to load - this player does it in about 5 seconds.Compared to a friend's more expensive (but slightly older) player, the upscaling of DVDs is MUCH better on this unit. DVDs tend to sound quite bass-heavy though.Playing blu-rays, the sound is clear and balanced - nice amount of bass, but balanced across the whole frequency spectrum. Haven't got round to the internet stuff yet, as we haven't got any Ethernet cables that reach from the router to the living room.In my opinion, if you've been hanging back on getting one you should absolutely grab this while it's on sale.


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Attention: All Sand Drag Racers - Purse Change!
Written by Administrator Friday, 20 May 2011 17:42
Hello Sand Draggers,
Due to recent events, the following will take effect immediately: 100% of the racer entry will go to the purse in each class. There will only be 3 winners in each class: 1st, 2nd & 3rd.
1st place gets 50% of the total purse, 2nd place gets 30%, and 3rd place gets 20%.
There will be discussion on next month's Small Gun Shootout during the May 22nd Test N' Tune on Sunday for those that wish to enter the shootout. Those that wish not to enter the tournament may still enter the regular race. This will also be discussed and posted up on the official website.
Please pass the word on. For any questions, please feel free to contact us at support@kalaeloaracewaypark or at 782-7432.
Michael Kitchens
Track Coordinator
Kalaeloa Raceway Park


text: Published on May 4th, 2013 | by admin Candy Crush Saga Level 75 Currently only the above YouTube video is available for Candy Crush Saga Level 75 to guide and show you. If you still need help, please drop us an email. Tags: Level 75 Related Posts No related posts found! Comments are closed.


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Spas93 wrote:Anyway, as always fantastic artwork yet again.
Using your quote, to respond to you.Sigment Kurosai wrote:We all know that he can have wings. The problem for him is that he seems to have yet to be able to call upon them at will. I'm merely thinking that (in true anime style) the emotion trigger of Mimi being in such danger will allow him to use his wings for the first time since he first obtained them.
Tenshi Nova wrote:I really do hope Minnie and Mimi start a love/hate relationship, "frienemies?" I believe is a popular term for it.
Tenshi Nova wrote:Why would Him start a war against immortals demi-immortals?
Tenshi Nova wrote:no Mimi won't become a spirit. If she died, she would remain dead.
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Ningbo Polysun Energy Co., Ltd.
Tel: 86-574-88279030
Pakistan office telephone no.:03100070963
Fax: 86-574-88279050
Email: firstname.lastname@example.com
Web: http://www.polysunny.com
Welcome to Ningbo Polysun Energy Co.,Ltd., reorganized in 2010. We are focus on100W, 150W, 200W, 250W mono solar modules with high quality and best price.
We have office in Pakistan.
1. LAHORE office, telephone no.: 04236300412, 03100070963 Address:KHURSHEED BUILDING 10ABBOT ROAD, near P.T.V Station, LAHORE, PAKISTAN
2. Gujranwala office, tel phone: 03334433408, 03018711300
The company has two production lines, total capacity is 20MW solar modules one year; Our products are exported to Pakistan, USA, UK, Singapore and other countries.
The products approved by CE, production and testing procedure is according to ISO9001 exactly.


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(Ken Long, and Bruce Bursten, 2013 spokesman at the Long Lecture)
Ken and Nancy Long
Ken Long, a native of northern Indiana, was educated in a one-room school at Wakarusa High School, Goshen College, Michigan State University and The Ohio State University. He came to Westminster in 1962 as an Instructor of Chemistry. After promotion to Professor of Chemistry, he served as Chair of the department for 16 years. Earlier he served as Assistant Dean of the College for four years. He taught chemical principles, radiochemistry, a course for non-majors, and Inorganic chemistry, retiring in 2002.
Ken was active in the American Chemical Society and its Penn-Ohio Border Section, a Sigma Xi chapter, the National Association of Geoscience Teachers, and the Field Conference of Pennsylvania Geologists. For nine years he was a member of the governing board of Goshen College, serving as secretary, vice-chair and chair of the board.
Nancy, a native of central Ohio, was educated in West Liberty, Goshen College and Clarion University. She was a professional librarian for 20 years in the Shenango Valley Library, serving as children's librarian, reference librarian and as administrator.
Both Ken and Nancy have long been active in the Mennonite Church in five states. They spent a year teaching English at Northeastern University, Shenyang, China.


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Find boats to sail on and apply for positions.
Brokerage / New Boat Sales
Milton Keynes, Buckinghamshire, England, UK
Becoming a member the First Class Nautical Members Boat Club is by far the best boating decision you could possibly make. The club, open to all is commercially owned and operated and is neither a time-share nor a shared ownership...
Our synthetic teak boat decking is Fully UV stabilised Superior resistance to staining and denting Virtually maintenance free Can be jet washed and sanded Non slip even when wet Looks fantastic and even feels like real...
Upon request
Beneteau Oceanis 343
Nowhere will you find a 34-foot yacht with such spacious accommodation! Coded for 8, category 2 (60 miles offshore). This 'Owners' layout sleeps a maximum of 6 in two double cabins and saloon and represents fantastic value. Based in Woolverstone, just outside Ipswich, the marina is set in 22 acres of glorious parkland on the sheltered banks of the picturesque River Orwell. Here is a great base from which to sail locally or to explore the East Coast. FlexiSail operate affordable boat sharing out of Ipswich, Hamble and Lymington with a large fleet of new and nearly new boats from 32 - 43' 'Boat membership' is an increasingly popular and cost effective alternative to chartering and ownership. Pippin is available on FlexiSail's Yachting membership and corporate membership scheme, a fantastic alternative to chartering. Our FlexiAnytime membership shares the time on a yacht between a small number of members (1 owner plus a maximum of 7 members). This gives each member the equivalent to 6 weeks or 42 days per year sailing, which is more than enough for most of us! We offer 2 alternative schemes for further flexibility - our long weekend orientated 'FlexiWeekender' membership and our 'FlexiMidweeker' membership for midweek sailing; If you have previously chartered do you remember the anxiety beforehand not knowing quite what to expect on arrival and therefore what you need to bring with you? With FlexiSail you are a member on the one boat – one you are totally comfortable and familiar with and which is fully kitted out with everything that you will need right down to a corkscrew! FlexiSail is in fact the closest you can get to owning a boat. You know exactly what to bring each time (just your wet weather gear, food and drink, and bedding if overnighting), and you are safe in the knowledge that the boat will be clean, welcoming and ready to enjoy. To find out more about how you can enjoy the benefits of Boat Membership: Call Nigel Rodliffe on 07766 007889. Email: firstname.lastname@example.com http://www.flexisail.com


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Making Great Impressions, Building Strong Relations
Natasha Golding Manager - Corporate Communications +65 6305 3820 email@example.com
Back to News Centre
Get regular updates on the Jebsen & Jessen Group of Companies South East Asia. The eMackerel delivers the latest news and activities straight to your inbox. Subscribe now - it's free. For enquiries, please contact us at email@example.com


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Carnival Breeze pictures
Image 1 of 65
Carnival Breeze in the shipyard
The Carnival Breeze seen in the Fincantieri shipyard in Monfalcone, Italy.
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Ashville House
Ashville House is a spacious, family-run guest house just 2 minutes walk from Killarney town centre. Our modern guest rooms feature every comfort and convenience and a delicious breakfast is included in the rates. Enjoying peaceful surroundings yet close to all the best restaurants, traditional Irish pubs and shops, Ashville House is within walking distance of Killarney National Park and Ross Castle. Many of Killarney's most popular attractions, including Muckross House and Gardens, Killarney Lakes, Ladies View, the Gap of Dunloe, McGillycuddy's Reeks and Torc Waterfall, can be found within half an hour's drive from us. Our helpful reception staff will be more than happy to assist you with anything you need, from booking a tee time at one of Killarney's many golf courses to booking a tour of the Ring of Kerry. Ashville House is located on the main Tralee Road (N22). Private parking is available for all guests. Check-in 3pm-11pm, check-out 11:30am Cancellations must be received at least 72 hours in advance. Credit cards are accepted. A full Irish breakfast is included. |
Availability & Rates
To view availability and prices please select dates and click 'Update Dates'B&B Facilities & Policies
- Breakfast Included
- Cable TV
- Child Friendly
- Cots available
- Credit Cards Accepted
- Fax Service
- Free City Maps
- Free Internet Access
- Free Parking
- Free Wifi
- Hair Dryers
- House Keeping
- Internet Access
- Laundry Facilities
- Lounge
- Luggage Storage
- Non Smoking
- Parking
- Tea/Coffee Making Facilities
- Towels Included
Cancellation Policy
This property has a 3 day cancellation policy. Failure to cancel within this time will result in a cancellation charge equal to the first night of your stay.DirectionsShow MapHide Map
Ashville is just 2 minutes walk to Killarney Town centre - with its restaurants and pubs. An ideal base for golfers and for touring Southwest Ireland. The property is just off the N71.
Located Near
Situated just 2 minutes walk from Killarney Town on Rock Road on the N71, Ashville House is within easy reach of the town centre with its many restaurants, pubs and shops.


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quote:When did Sandler stop including his non-famous buddies in his films (qb in Waterboy, homeless guy in Happy Gilmore, etc)?
quote:No chance
quote:How does this make less than Jack and Jill? I guess because of the R rating which means he's going to go back to making family comedies that are a sure thing.
quote: Happy Gilmore
quote:Billy Madison
quote:Big Daddy
quote: Little Nicky
quote:50 first dates
quote:How old are you? If you don't mind me asking.
quote: hear ya. I'm 26 with a low IQ
quote:what comedies did you really like around that time period (90's)?
quote:Happy Gilmore Awful.
quote:I'm no fan of his recent work but the hate he gets on here is astounding.
quote:Jack and Jill dude.
quote:Just because the movie is stupid funny doesn't mean only stupid people like them
quote:Happy Gilmore, Billy Madison, Waterboy, Big Daddy are all very funny movies.
quote: No they aren't going to make you think or make some statement about civilization
quote:You sound like a pretentious douchebag


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Lili Duda, VMD
Ultima Vez Modificado: 1 de noviembre del 2001
Dear OncoLink "Ask the Experts,"
Our dog has been diagnosed with myxofibrosarcoma. Given the tumor's size, location and aggressiveness, and the consequent difficulty of securing a tumor-free margin without extensive penetration into the chest, we are considering palliative care options. This is where the questions arise:
Anything you can tell us would be most helpful.
Lili Duda, VMD, Editor of the OncoLink Veterinary Oncology Section, responds:
Superficial ulceration of large tumors is a frequent complication. It is unlikely that fluid-filled pockets within a tumor are much of a contributing cause of surface ulceration, and aspiration is not likely to be very helpful. However, in the few cases where a tumor does contain a solitary, large fluid-filled center, aspiration might be helpful to relieve the pressure. Ultrasound is recommended to confirm the presence of a fluid-filled area prior to aspiration. The procedure should be performed using sterile conditions in order to minimize the risk of infection. Another palliative treatment option that might provide temporary relief is radiation therapy. Chemotherapy might also provide short-term palliation in some cases.
For locally invasive tumors that either do not metastasize or metastasize late in the progression of the cancer, tumor associated problems are generally localized problems. The presence of necrosis, ulceration and bleeding are part of the cancer "running its course", and it is these types of complications that often result in a decision for euthanasia. Systemic problems are unlikely to occur unless the localized infection and inflammation at the tumor site become so severe that the problems become systemic. Even if metastasis does occur, it is often asymptomaticit is the primary tumor that causes the majority of the symptoms in most cases.
For most purposes, low-grade soft tissue sarcomas have a similar clinical course. Some tumors do tend to be firmer and more solid, and some tend to be softer and more fluid. In addition, many tumors, and in particular rapidly growing tumors may have a central area of dead, liquefied tumor cells. However, the particular type of sarcoma (fibrosarcoma vs. myxosarcoma for example) does not make a difference in case management or outcome.
Dec 7, 2010 - Rituximab may be a better option than watchful waiting in some lymphoma patients, and a new treatment option appears effective for relapsed or refractory Hodgkin's lymphoma, according to two studies being presented at the annual meeting of the American Society of Hematology, held from Dec. 4 to 7 in Orlando, Fla. Other research being presented will highlight new options for the standard treatment of advanced asymptomatic follicular lymphoma; mantle cell lymphoma; and early, unfavorable Hodgkin's disease.


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Designer Doll Divya
No longer available
- Overview
Dressed in a traditional Indian dress in a medley of pretty fabrics and golden sandals, our Designer Doll Divya is both stylish and huggable. She has long, slender limbs and sweetly embroidered features. Felt flowers adorn her hair.
- 8" wide x 27.5" long x 4" thick
- Handmade of soft linen with embroidered face and braided yarn hair.
- Clothing is crafted of a medley of fabrics, including felt, printed cotton percale, tulle and grosgrain ribbon.
- Ages 2 years and up.
- Imported.
- Dimensions & Care
- Surface is washable with warm water and mild soap.
- Shipping Info
- Please allow 5-7 business days for delivery. Delivery estimate includes monogrammed and gift-wrapped items.


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JLS Tickets
Find the JLS tickets you're looking for on viagogo, the world's largest ticket marketplace. Select an event to view the range of tickets available or view the JLS tour on a map to find an event near you. You can also sell your spare JLS Concert Tickets on viagogo, and listing tickets is free. All JLS tickets are covered by the viagogo Ticket guarantee!
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JLS are so named as an acronym for the suitably self assured moniker Jack the Lad Swing. Although they didn't emerge as the overall winners of 2008's X Factor (Alexandra Burke being crowned winner), the boyband were signed to Epic Records and have already amassed a formidable legion of fans. Aston Merrygold, Marvin Humes, Oritsé Williams and Jonathan 'JB' Gill audition for the fifth series of X Factor - with Humes having previously been a member of the now disbanded group VS created by Blue's Simon Webbe. Having being taken under the guiding wing of X Factor judge Louis Walsh, JLS often looked sure for elimination as they consistently featured in the bottom two of the competition. JLS overcame adversity in the form of the formidable Simon Cowell with their performance of Lonestar's 'I'm Already There' which also saw the group garner the most votes in the semi-final stage of the competition. After losing out in the final of the competition, JLS took part in The X factor Live Tour, playing across the UK alongside fellow contestants. The band's debut single 'Beat Again' went to number one in the UK singles charts after shifting 100,000 copies in the first week of release. If you have any questions about using viagogo, visit our Frequently Asked Questions page.
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Greetings all.
I am currently seeking contact with other ex-members and whistleblowers regarding the Illuminates of Thanateros, and allegations of Satanic Ritual Abuse. Ostracised and slandered by the British 'occult scene' I have gone from appearing on TV and publishing works with a (supposedly 'respectable') influential occult publisher to being 'laughing stock'; famous for making 'false allegations'.
This year, after turning to the Police with information regarding a specific case of Satanic Ritual Abuse regarding the IOT and Colin Batley (http://www.bbc.co.uk/news/uk-wales-12690580), I was sectioned.. but after only 2 days it was officially decided I am NOT paranoid and delusional.
I have the interest of a sound minded reporter famous for going against the grain and bringing down high profile paedophiles, such as with the case surrounding Jimmy Saville. I am hoping others on this board who know what I am talking about, such as deathcultreject, will contact me. It is time to BLOW THIS OPEN. Together we can do it. I might even manage it without others, but..


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Q.U. wrote:So are Minecraft and Terraria, but there you go. Everything with blocks is a Minecraft clone. Just like anything with 2 teams of 5 payers on one arena is a DOTA clone according to many.
People just don't care to differentiate at all. So it doesn't surprise me really.
It's happened to every genre, visual design and/or play mechanic. How many open world action games were called GTA clones, how many early FPS games were called Doom clones. Right now MOBAs are exploding and there's so many rushing to market, give it a few years and let the blatant cash in copies fall of the radar. And yes there are plenty of clones of Dota floating around some are legit but there's plenty of band wagon jumpers, Guardians or Middle-earth and the DC one are most obvious. Right now the same thing is happening with these open ended games that use a 2D,blocky or voxel design.


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But that was nothing compared to the thousands of words of heated comments by readers that followed, many excoriating the magazine for being stale, out of touch, racist and elitist. "Cathy, why are you even reviewing [Vogue]?" wondered one reader. "Perhaps they should be reviewing you?" But another confessed that despite its misgivings, "I read it faithfully.... Vogue is Vogue. You know, if God let some typos into the Bible, you wouldn't stop reading it just cuz, would you?"
In a follow-up post last week that responded to some of her online buddies, Horyn delivered a rather backhanded compliment: "If I admire Anna Wintour for one thing, it is that she runs Vogue as she sees fi t."
A Vogue spokesman told WWD, "We're always very interested to hear what Cathy Horyn has to say, and in this case, her readers as well."
Horyn's Washington Post counterpart, Robin Givhan, also tackles the new fashion commentariat in the September issue of Harper's Bazaar. "Fashion has become like sports, with its own version of the Monday-morning quarterback," she writes. "Mostly, all the chatter is good for the industry. The average person, too often estranged from fashion, is taking ownership of it." She adds that given her job, "you'd think my initial reaction to the democratization of fashion criticism would be horror. How dare these self-proclaimed citizen journalists trespass on my turf? But no. I didn't protest. I launched my own show-season blog."
As Vogue prepares to launch its own Web site, that approach may be more relevant than ever. — Irin Carmon


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Common feedback from travellers is that their time spent on Kangaroo Island was their most memorable in their whole Australian experience.
We shouldn't be surprised. After all…
Kangaroo Island ("KI" to the locals) is a short flight from Adelaide or a ferry ride from Cape Jervis. There's so much to do on this island. Explore untouched bushland, fish on pristine beaches, see the wildlife, go on an eco tour or charter.
Some like to call Kangaroo Island a zoo without fences. Kangaroos, koalas, wallabies, penguins, echidnas and bird life all call the island home. Seal Bay is the only place in Australia where you can walk on the beach amongst a colony of endangered Australian sea lions.
Kangaroo Island gives you Australian nature and wildlife at its very best.
With all the wildlife and natural beauty you could be forgiven for thinking Kangaroo Island is uninhabited by humans. Although the resident population only numbers 4,500 people, its an island with fascinating human stories to tell. From the wild early tales of escaped convicts and sealers to proudly being the home of Australia's first free settlement it is a place with a history unlike anywhere else in Australia.
Today Kangaroo Island is home to farmers, winemakers, artists, chefs and many more welcoming people. They are proud of what they have and take delight in showing it off to visitors.
Rugged coastal cliffs, sheltered bays cupped between steep headlands, vast native bushland and rolling hills of farmland are just some of the landscapes on offer. Remarkable Rocks and Admirals Arch are surely two of Australia's most fascinating coastal landmarks.
On Kangaroo Island 'deserted' beaches are just that – unless you count the kangaroos and sea lions that occasionally visit.
From the ultimate in luxury at Southern Ocean Lodge to quality hotel accommodation or simple lodgings, Kangaroo Island has accommodation to suit everyone.
See here for the best travel offers to South Australia and Kangaroo Island from our United States and Canadian travel partners.
Kangaroo Island is 155 kilometres (96 miles) across and literally packed with places to see and things to do. Which means you need to give yourself time to explore its wonders.
Kangaroo Island. An experience you'll never forget.
Stunning wildlife, pristine beaches, fresh produce, gourmet food, wine and luxury accommodation; Kangaroo Island has it all. Plan your next holiday with the Kangaroo Island Visitor Guide and let yourself go!
Download a Kangaroo Island map to help find your way around the main towns - Penneshaw, American River, Kingscote - and the island's wild west.
Here are some great ideas for you to try while you're in the area.
There are plenty of events in Kangaroo Island. Here are some ideas you might like.


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Brooklyn Slate Coasters, Black - set of 4
Country of Origin: United States
Region: New York
Brooklyn Slate company is a family operation from the slate quarries in New York state and Vermont to the hand-finishing done in their Brooklyn studio. These slate coasters absorb liquid naturally and add a rustic charm to your table.
Each coaster comes with cork pads to cushion the bottom and protect your table.
Produced By: Brooklyn Slate Co.
View All Products from Brooklyn Slate Co.
Brooklyn Slate Coasters, Black - set of 4 Product ID: 02807 |
Price | Qty |
$26.95 x | |


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quote:Actually, it's very condensed. Some characters are missing, and some have been combined. It was almost 1100 pages, so there was plenty of material for 13 episodes.
quote: timeline in the book about a week
quote:They've mentioned why a few times, just not directly.
quote:The idiot kidnapping the girl in the shed is an awful plot and is the only thing I dislike about it. Was the story this bad in the book or is it just bad due to the awful acting
quote:I forget
quote:I've realized that the only similarity between the book and the TV show is: The Dome.


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John J. O'Brien Jr, MD
About the Practice
Practice Philosophy
I want all my patients to have a natural and refreshed appearance and don't want them to look 'operated on' in any way. That can be achieved often through a combination of surgical and non-surgical procedures and treatments.
I take a 'hands on' approach and try to educate my patients as much as possible about all of their options while also providing them with realistic expectations. And I provide the best care to every patient as I look forward to helping patients meet their individual aesthetic goals and dreams. I offer personalized consultations and procedures to all of my patients.
People should be honest with themselves about what can realistically be achieved and what plastic surgery can do for you to improve your image and self-confidence.
Practice Specialization
Dr. O'Brien specializes in Breast Augmentation, Body Contouring, Facelifts, Hand Rejuvenation and Liposuction.
Dr. O'Brien's clinic offers Med Spa services in order to provide a variety of cosmetic treatments to improve the condition of the skin and body. Dr. O'Brien prides himself on providing the highest quality overall customer care experience.
Face: Browlift, Endoscopic Browlift, Blepharoplasty, Facelift, Rhinoplasty, Otoplasty, Lip Augmentation, Chin Implants
Breast: Breast Augmentation (implants), Breast Lift, Breast Reduction, Breast Reconstruction, Male Breast Reduction
Body: Abdominoplasty, Brachioplasty, Body Lift / Thigh Lift, Liposuction, Buttock Augmentation, Calf Augmentation, LipoSelection (Vaser® technology), Belt Lipectomy, Fat Grafting
Laser: Laser Hair Removal, Laser Peel
Injectables: Botox® Cosmetic, Dysport® and filler/ injectables: Juvederm®, Restylane®, Perlane®, Voluma™, Radiesse, Sculptra®
Med Spa: IPL Photorejuvenation, Facials (Signature European Facial), Acne Facials, HydraFacial™, Thermage™, Microdermabrasion (Crystal), Chemical Peels (Obagi Blue Radiance, TCA, Glycolic, Jessners, Tri-Plex), Dermaplaning, Dermafile™, Advanced Micro (Micro Plus Peel), Red/Blue Light Therapy, SmartXide DOT Laser Therapy, Spider Vein Treatments, VISIA Digital Skin Analysis, Latisse™, CoolSculpting®, Rejuvapen™, Makeup Lesson/Application, Waxing & Brow Tinting.
Background & Certification
Board Certification
American Board of Plastic Surgery, 1996
Professional Background
Syracuse University, B.S. Biology / Honors
State University of New York, MD
State University of New York at Buffalo, General Surgery Residency
St. Joseph Hospital/Texas Medical Center, Plastic Surgery Fellowship
Teaching Appointments
Dr. John J. O'Brien, Jr. lectures at both state and national meetings regarding plastic surgery and writes articles for various medical publications.
Publications and Presentations
As a highly-regarded expert in plastic and cosmetic surgery, he has lectured at both state and national meetings regarding various aspects of plastic surgery. Dr. O'Brien has written articles and book chapters for various medical publications and has provided expert consult to a number of companies in the plastic surgery and med-spa arena.
Awards & Honors
Included in "America's Top Surgeons" by the Consumers' Research Council of America
Named one of "America's Top Doctors" by Castle Connelly
2013 Vitals Patients' Choice Award
Affiliations & Memberships
Hospital Affiliations
Bayfront Medical Center
Palms of Pasadena Hospital
St. Petersburg General Hospital
St. Anthony's Hospital
Bayfront Plaza Same Day Surgery
Society Memberships
American Society of Plastic Surgeons
American Society of Aesthetic Plastic Surgery
Florida Society of Plastic Surgeons
Tampa Bay Society of Plastic and Reconstructive Surgeons
Offices Held
Dr. O'Brien has held leadership roles in both state and national societies, including the President of the Tampa Bay Society of Plastic Surgery and the Florida Society of Plastic Surgery, has been on the Board of Governors and continues to advocate for patient safety issues in plastic surgery with t he Florida Board of Medicine. In an effort to be the board certified Tampa plastic surgeon you can trust, Dr. O'Brien continues to update and extend his training by attending national and local plastic surgery conferences, classes and meetings while updating board certifications.
Your Consultation
MyLooks® provides free consultations and customized treatment plans tailored to suit each patient's individual needs.
Staff & Facilities
Surgical Facility
AAAASF Accredited Facility
Florida-based MyLooks® is a leading cosmetic and surgical service provider dedicated to helping women and men achieve their personal aesthetic goals. Each MyLooks® clinic provides a high-quality total experience. All of our surgeons are board certified by the American Board of Plastic Surgery. All MyLooks® clinics offer procedure customization, a safe and clean AAAASF certified environment, patient financing, and complimentary consultations. More information is available at www.MyLooks.com.
Skin Care Products
Obagi: Full Size Nu Derm Kits (N/O and N/D), Travel Kits Nu Derm, Foaming Cleanser, Toner, Clear, Exfoderm/ Exfoderm Forte, Blender, Sun Shield SPF 50, Healthy Skin 35, Hydrate/ Hydrate Luxe, Retin A 0.5%, Retin A ).1%, Elastaderm Eye Cream/ Eye Gel, Elastilash, Elastiderm Dectollage System, Clenziderm Foaming Gel, Clenziderm Theraputic Lotion, Metro Gel, Obagi C Cleansing Gel, Obagi Vit w/HQ, Obagi C Exfoliation Day Lotion, Obagi C Therapy Night Cream, Obagi Sun Guard
Languages Spoken
Payment Options
Payment for services is expected at the time of your appointment. We accept cash, checks and credit cards. Financing is available for those patients undergoing elective cosmetic surgery. We offer financing services thru Care Credit and will provide you with this information upon your request or you can visit: www.CareCredit.com
John J. O'Brien Jr, MD
7855 38th Ave. North,
Saint Petersburg, FL, 33710,


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Well had to let my hair down this last weekend and have a little fun.
Don't go out very often at all. But I had a nice time with some of my
girlfriends this weekend and had a couple friends over on Friday.
Thought I'd share the pictures for the heck of it. And if you ever
have a wild weekend or just pics of fun, share!
We don't drink much if we go out, so we were much
more intoxicated taking pictures at the house. hehe
With this last picture prolly being the worst and most telling.
Who wears sunglasses in the house and takes a picture like
they are falling over!!?? Its just a ridiculous picture.


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New Senior League Baseball Bat! This season's Prodigy Legit blow previous models out of the park! The hottest-selling youth big barrel bat is back again this season with a fresh new look and a new, stronger alloy. The Worth Prodigy Legit draws it's name from its legit performance and its Alloy construction. Worth's Alloy is its strongest yet, which allows for the thinnest walls and shells for absolute MAXIMUM trampoline effect! If you've ever swung a Prodigy before, you'll notice a stark difference in durability as well. One thing that's stayed the same though is the HUGE 2 3/4 inch barrel. This creates the largest hitting surface in the game, so you can CRUSH anything that comes your way! At the end of the barrel, a Center Load end cap is designed to allow increased barrel flexibility. The taper to the handle is 30% thinner due to Whiplash Technology, resulting in reduced weight and increased bat speed. In addition, the Prodigy Legit features a balanced weight distribution for maximum control and consistency. This Worth bat is also proudly designed and manufactured in the U.S.A. Worth: 100 Years of Performance Through Technology! The Prodigy Legit features the USSSA 1.15 BPF Stamp. It is backed by a Full Twelve (12) Month Manufacturer's Warranty. Free Shipping!
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Timer wrote:you gonna do arch's character as well ?
Was I really that good with my rundown? Maybe I should do this for a living. Alrighty, here it is.Archrival wrote:@Timer: Yes I would like a similar run down as well.
Timer wrote:edit: Highlighted my tagged skill's for clarity.
It was a fun sidequest in New Vegas finding and reprogramming 'F.I.S.T.O.' the whore-bot. Such a thing is not unknown to my brain... so I naturally jumped to it. Nearly facepalmed when I realized she merely wanted a body-guard.Timer wrote:Robot's for self defense only i think I don't think robophilia is on the list of acceptable topics for her :p
I'm honored, really.Archrival wrote:Very good, I'm impressed with your thought process on characters.
I made sure people here knew the Fallout universe well before I started this. I even picked your brain a little before I started the thread in the first place- eventually leading to you saying yo have played Fallouts 1, 3 and New Vegas so I'm not worried about you. For all I know you know more about fallout than I do.Archrival wrote:Of course this is also reliant on your players, if they have little or poor understanding of what your world/creation is like then the Characters are likely not to be as good either.
That's good because I did.Timer wrote:I'd ignore the Repair for her personality.
As I may or may have not slipped already, I'm expecting 4, but 3 would also be acceptable. But assuming everyone in this thread will be constant we may have 5 or more.Timer wrote:So we just need some more people then...
East coast cape cod post apocalyptic. Not far from the Capital Wasteland so it will likely be exactly the same as Fallout 3's attire. With a much less inhabited environment however, people will likely have made their own clothing from the land. Being so east- and now having access to fresh water some plants have started to grow. It's not lush by any means, but it's something.I do have questions such as weaponry and armour, in terms of what things you may have uniquely made for this setting that we may come across and what the clothing style may be e.g NV is very much western/gambling while 1-3 is more your typical grungy post apocalyptia.
Archrival wrote:Glad you've given that thought but I truly meant what you've added given that you have some creative licence with this area, adding gangs, companies hell even new creatures due to some new Fallout inspired background you have freshly created.
Birdofterror wrote: No sunset Saspirilla here though, that there's a western beverage.
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Gevalia Mocha
Smooth, satisfying and simply delicious, Gevalia Mocha is crafted with your sweet tooth in mind. A mouthwatering fusion of mountain-grown beans and rich chocolate syrup offers a decadent treat that's worth savoring. TASSIMO Brewer Required.
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Rated 5 out of 5 by Mochame Just what I've wanted!
I love mocha and all the coffee shop mochas are too sweet. But this one is just right. This is a keeper. Thanks Gevalia.!
December 7, 2014
Rated 5 out of 5 by grannyjean great coffee
Love the tummy warming feeling when drinking a cup of this. I only wish Gevalia would package all of their seasonal flavors in the tdisks as well
May 15, 2014
Rated 4 out of 5 by Roaster609 What a surprise
I rarely drink flavored coffee, but I ordered the Gevalia Mocha T Disc for others in my office. When my order arrived I decided to try one. Wow, is all I can say. While it is really more of a coffee flavored hot chocolate than a chocolate flavored coffee, it is very good and I would recommend it to everyone.
March 10, 2014
Rated 5 out of 5 by SandynUtah My Favorite Tassimo Coffee
I tried many T-pods and this is by far my favorite...I'm so addicted. Rich and creamy taste...no more trips to the coffee shop for a delicious Mocha coffee.
December 27, 2013
Rated 5 out of 5 by CalKelly68 Excellent flavor.
I am a light weight coffee drinker and this is the best that i have found, aside from paying $4 for a single Starbucks White Chocolate. This has won me over. Exceptional bang for the buck!
December 31, 2011
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3 years, 3 months ago
"Tassimo Gevalia Mocha Artificially Flavored Coffee" As declared on the package, contains 23grams of sugar per serving.3 years, 3 months ago
TASSIMO Gevalia Mocha contains 23 grams of sugar.3 years, 3 months ago
Age: 35-44
Gender: Female
Drink Gevalia: All the time
Length of use: So long I can't remember
Take Gevalia: With milk and sugar
3 years, 2 months ago
A T-cup stands for Tassimo, while the K-cup stands for Keurig. Two totally differant machines that work, basically, the same way.Age: 35-44
Gender: Female
3 years, 2 months ago
No. TASSIMO T DISCs are designed with proprietary barcode technology and will only work with TASSIMO Brewers.3 years, 2 months ago
3 years, 3 months ago
Tassimo Gevalia Mocha has the following nutritional information. Calories - 140; Calories from Fat 30; Total Fat 3g, Saturated Fat 2.5g, Trans Fat 0g; Cholesterol <5mg; Sodium 200mg; Total Carbohydrates 26g, Dietary Fiber 1g, Sugars 23g; Protein 1g.3 years, 3 months ago
When will this product be available for purchase again, online and in stores?
Drink Gevalia: Evening
Length of use: So long I can't remember
Take Gevalia: With milk and sugar
2 years, 8 months ago
Gevalia's stock changes on a daily basis. While Gevalia does its best to keep all products available for customers, occasionally the supplies run short due to popular demand. Gevalia is working to have all products available to our customers.2 years, 8 months ago
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Is there a specific order in which I should add the coffee, syrup, and milk?
Drink Gevalia: All the time
Length of use: Within last year
Take Gevalia: With milk only
1 year, 10 months ago
We recommend the following. However, you can do it either way.1.Place your desired 12 fl oz mug on the cup stand.
2.Shake the flavored Chocolate Syrup T DISC and insert it into the brewer first; when the green Auto light comes on, press the button.
3.When the orange Stand-by light displays, replace the Syrup T DISC with the Espresso T DISC; wait for the green Auto light, and press to start.
4.Watch as the mug fills, then enjoy a delectable, chocolaty treat.
1 year, 10 months ago


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Go check out the new Satans Excrement comic!
Something really crazy awesome happened yesterday. About a year or two ago I commented on one of my favorite bands facebook page and told them it would be cool if they made a song called IT GETS WORSE to make fun of the it gets better thing plus their fans who think their music is only getting worse, and I woke up yesterday to hear a demo of that same song posted to their youtube.


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Corot Shiny Crocodile Fumé Zip Around Wallet
$ 2,800
This shiny crocodile wallet is not only unusually beautiful, it is also an investment in lasting style. The wallet has a zip-around closure for security and plenty of room for cards, coins, and bills.
- Solid color, Zip closure, Lined interior, Internal zip pocket, Internal card slots
Composition: Crocodile leather
Depth: 1.0 Inches
Height: 4.1 Inches
Width: 76.1 Inches
Made In Italy
Style: 114076VBGH15074
Select color
Select size (Size Guide)
- OneSize
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People Pets
October's Cutest of the Cute!Each of these pets won our Click the Cutest contest last month – so they're scientifically proven to be adorable! Want your pet to get this honor next month? Enter to play!
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- Scandal Recap: Fitz and Mellie Plan Her Political Future as the Show Takes on Ferguson
- Read the Cover Story: What Caused This Teenager to Murder His Parents?
- Harrison Ford Suffered 'Bad Laceration' to Scalp in Plane Crash, Says Eyewitness
- Twitter Flooded with Show of Support for Harrison Ford After Plane Crash
- Aviation Expert on Harrison Ford's Crash Landing: 'Everything He Did Was Perfect'


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American Lighting Brand 15 Watt LED Priori Plus Undercabinet Light Fixture. Full length tempered prismatic glass lens, hinged lens with magnetic closure. Can be installed either hard wired or with optional power cord (#043A-PC6-BK). An optional direct wire box is available and allows for quick installation with the added benefit of optimal light distribution over the work area. Mount the fixture near the front edge of the upper cabinet for the best task light. You can abut multiple fixtures together without any additional accessories/linking cables, or you can link multiple fixtures together using optional linking cables.
Suitable for commercial or residential lighting.
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Coordinating Items
Beach Chair Set
Item# G0446
Her My American Girl® doll will be ready to reserve the best spot on the beach! This set includes:
- A folding beach chair
- A hibiscus-printed basket to hold all of her favorite refreshing treats
- A pretty leaf-shaped plate
- Plenty of pretend snacks: shave ice with a cup, a coconut drink, two pineapple fruit wedges, and two fruit kabobs with orange, pineapple, kiwi, and more!
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She's the doll you create—and bring to life online!