2305 labeled duplex. As might be anticipated, none of the simulated isotropic spectra provide an especially good fit to the dynamic signature of the distinctly anisotropicI0 long duplex DNA. The spectrum does, however, contain features found in isotropic simulations in the 20-100 ns T~ range.]' For the present purposes, the signature of a large D N A duplex is easily distinguished from that of the hairpin and single-stranded forms.I2 The spectra presented here suggest that spin-labeled D N A in combination with EPR is a simple and powerful tool for the structural evaluation of regions of D N A suspected not to exist in the B form.I3 Large and characteristic differences between duplex and unpaired bases should permit detection of the latter in DNA of any size. Furthermore, the EPR method is not subject to one major problem common to all chemical reactivity probes, that of dynamic equilibration of conformations. In fact, the nanosecond time scale of the EPR method should permit quan-titation of such equilibria (e.g., duplex/cruciform equilibria). This spin label method of structure evaluation may also find use as a preliminary characterization of small DNA's whose study by N M R or X-ray diffraction is contemplated. Whether spin probes will reveal distinct signatures for other nucleic acid structures (e.& A-, 2-, and bent DNA, R N A structures) remains to be found.


Introduction: of capital importance.- Introduction: of capital importance.- Overviews.- Why companies invest in information technology.- Evaluating the feasibility of information systems investments: recent UK evidence and new approaches.- The Strategic Dimension.- A portfolio approach to evaluating information systems investments and setting priorities.- Evaluating your computer investment strategy.- The real value of strategy formulation for information technology.- Assessing the value of strategic information technology investments.- Techniques.- Justifying IT investments.- Information economics: a practical approach to valuing information systems.- Beyond return on investment.- Risk and information systems: developing the analysis.- Process and Perspectives.- Responsibility for IT: a grey area of management.- Evaluation of information systems investments: towards multiple perspectives.


The in vivo survival of Co(a+b‐) red cells in a patient with anti‐Coa was studied using a small aliquot of 51Cr‐labeled red cells. The antibody reacted at room temperature without incubation and after completion of the antihuman globulin test with both reactions enhanced by ficin. Circulation of transfused cells was shortened with a T50 of 5 min. The patient's anti‐Coa titer rose following transfusion to 1:256. These data suggest that individuals with anti‐Coa should receive Co(a‐b+) red cells for transfusion.


Microlites in pseudotachylite veins from the Fuyun fault zone, northwest China, can be divided into four morphological groups: simple, skeletal, dendritic, and spherulitic. From the margin to the center of microcrystalline and microlitic pseudotachylite veins, the size of single crystals or crystal fibers becomes progressively larger from a few µm to as much as 15 µm. The morphologies of microlites vary from simple shapes, such as acicular and globular forms, to more complex forms such as skeletal, dendritic, and coarse spherulitic forms. In glassy pseudotachylites, only simple and fine spherulitic microlites, generally smaller than 5-6 µm, occur. These microlites have a varied mineralogy but are mainly made up of plagioclase (An20-70), and alkali feldspar, including sanidine and anorthoclase, as well as clinopyroxene, grossular garnet, biotite, hornblende and some magnetic minerals. The biotite and hornblende microlites have a variable Ti content, generally higher than that of biotite and hornblende fragments from the country rocks. The wide variety of morphologies and textures of microlites within the pseudotachylite, the presence of sanidine, anorthoclase, An-high plagioclase, pyroxene, and Ti-high biotite and hornblende indicate that these microlites are primary crystals formed from rapid cooling or quenching of a melt.


The present study was to evaluated the clinical value of anatomical thermal ablation to treat hepatocellular carcinoma compared with routine thermal ablation.


Total intensity and polarization maps at wavelengths of 6 and 20 cm are presented for 47 double radio sources with one-sided jets. There is a strong asymmetry in the degree of depolarization between λ6 and 20 cm : of the 37 sources with significant depolarization, 34 show less depolarization on the jet side than on the counter-jet side. There is also a significant asymmetry in the spectral index of the two sides : the jet-side spectral index is flatter by typically Δα = 0.1. By comparison, the asymmetries in flux density, peak brightness and separation from the nucleus are minor, and cannot be significant contributors to the depolarization asymmetry


Technology enhanced learning (TEL) is considered a key element for lifelong and cost-effective learning processes. Nowadays, with the rapid development and evolution of the Web 2.0 (e.g. wikis, blogs, etc.) new learning paradigms have emerged. Instead of a simpler model where students consume instructor-written documentation, it appears to be a natural process that users (or learners in this case) may become a prosumer (a combination of producer and consumer). In the context of TEL this implies the creation of a new species: The teaner (a combination of teacher and learner). Additionally, TEL is now exploring alternative forms of content such as story-telling and educational gaming. These two approaches, when combined, can be mutually beneficial, with games bringing the educational stories to life and with the stories providing a solid narrative backbone for the games. In this work, we propose an approach to merge educational gaming, interactive story-telling and collaborative creation of content, glued together by interoperable multimedia metadata. Finally, we discuss aspects of mobile learning and the challenges posed by adding a fourth dimension for the problem: letting teaners go mobile.


Technology-based assessment in special education has made advances during the last two decades. Whereas the first applications of computer technology for assessment were for scoring student test forms, contemporary uses support many other features and functions. These features include self-administration, software control of item presentation, response evaluation based on conceptual models or algorithms, decision making based on rules and criteria, prescription based on expert knowledge, and direct links between assessment and changes in instruction. Technology-based assessment generally refers to the use of electronic systems and software to assess and evaluate the progress of individual children in educational settings. Thus it encompasses both electronic versions of traditional measurement protocols as well as innovative assessment approaches that employ computers. Examples of approaches in technology-based assessment include:[1] * A video-based computer-assisted test able to learn the language preference of the student and automatically switch to it to increase the validity of its measurement; * Video segments from popular movies used as elements of a moral dilemma in a real-life, problem-solving test; and * Students viewing video segments of peers interacting in various social situations and entering their responses by simply touching a computer screen. In the world of technological evaluation these innovative approaches bring validity and relevancy to the testing procedure. A variety of factors have contributed to the current need for better assessment tools and procedures in our schools. Students being misplaced as a result of poor evaluations is one. Misplacements of students can have devastating results for both student and teacher. Such misplaced students tend to lose interest and drop out of school. Teachers who have misplaced students in their classrooms are often not properly trained to deal with certain behaviors or learning differences. Other factors contributing to changes in assessment practices are partially due to the growing population who qualify for IDEA (Individuals with Disabilities Education Act). Data reported in the 1994 U.S. Dept. of Education's Sixteenth Annual Report to Congress on the Implementation of Individuals With Disabilities Act show a 3.7% overall increase in students receiving special education services during the 1992/93 school year.[2] This growth in special education, although not huge, does include a significant number of minorities who have different cultural backgrounds and languages. The growing diversity of students in special education warrants new and innovative approaches to assessment practices. Minorities who qualify for special services require culturally relevant assessments, particularly in the areas of language and social behaviors. * Culturally Relevant Assessment It is important that minorities be assured of equal representation in special programs. It is well known that ethnic minorities are under-represented in advanced programs for the gifted, such as AEP (Advanced Education Program). Yet, there is an over-representation of certain ethnic minority groups that fall into special education categories such as Intellectually Disabled and Learning Disabled. Studies have shown, for example, that until recently there were approximately twice as many Mexican-American students in classes for the educable mentally retarded (EMR) in the U.S. as would be expected on the basis of proportion in the school population.[3,4] As far back as 1916, Miller pointed out that special or "backward" classes furnished "an easy means of disposing of (a non-English-speaking) pupil who, through no fault of his own, is an unsatisfactory member of a regular grade."[5] This over-representation of ethnic minority students in classes for the mentally retarded has been attributed to the indiscriminate use of psychological tests, especially IQ tests, combined with the linguistic and cultural orientation of school programs. …


Objective: To establish a method for simultaneous determination of 116 kinds of semi-volatile organic compounds in water by gas chromatography/mass spectrometry with solid-phase extraction. Methods: Water sample was extracted on Cl8 solid phase column and eluted with dichloromethane & ethyl acetate then separated by GC with an DB-5 MS capillary column. The interest analyses were analyzed by gas chromatography/mass spectrometry used all scan mode. Selective ion masses were used in quantitative measurement. Results: Enable to easily and effectively separate and determinate 116 kinds of semi-volatile organic compounds in water. In this method, broad linearity range, good linearity which correlation coefficient was greater than 0.9961, RF RSD was less than 4.92%, the average recoveries rates were between 81.6% and 119.8%. Conclusion: This method established was so selective, sensitive and exact. It has good adaptility to various water samples. It is suitable for simultaneous determination of 116 kinds of semi-volatile organic compounds in water.


In this research, we create a single-phase to ground synthetic fault by the simulation of a three-phase cable system and identify the location using mathematical techniques of Fourier and modal transforms. Current and voltage signals are measured and analyzed for fault location by the reflection of the waves between the measured point and the fault location. By simulating the network and line modeling using alternative transient programs (ATP) and MATLAB software, two single-phase to ground faults are generated at different points of the line at times of 0.3 and 0.305 s. First, the fault waveforms are displayed in the ATP software, and then this waveform is transmitted to MATLAB and presented along with its phasor view over time. In addition to the waveforms, the detection and fault location indicators are presented in different states of fault. Fault resistances of 1, 100, and 1,000 ohms are considered for fault creation and modeling with low arch strength. The results show that the proposed method has an average fault of less than 0.25% to determine the fault location, which is perfectly correct. It is varied due to changing the conditions of time, resistance, location, and type of error but does not exceed the above value.


The main objective of this research is to investigated the use of Glass Powder and other is Stone dust as partial replacement of cement and concrete production. In this research we analyze the strength of concrete made with using these waste materials one is Glass Powder and other is Stone dust. The Glass Powder is used as 20% replace by weight of cement and Stone Dust as the partial replacement of Fine Aggregate from 0%, 10%, 20%, 30% and 40%. The grade of the concrete here is M-25 and M-30 grade. It has been used as a replacement of fine aggregates in many literature works but this paper presents the feasibility of the substitution of marble waste for cement to achieve economy and environment saving. Slump Test was carried out for the fresh concrete whereas Compressive Strength, Flexure Strength and Split Tensile Tests were carried for the Hardened concrete. All tests are done at 7day, 14 day, 28 -day, and 56 days with 0 to 40% replacement of sand at an interval of 10%. Again above tests are carried out with 20% replacement of cement by glass powder. It is observed that the glass powder improve the strength and stone dust can be used as sand. Experiment such as specific gravity test of stone dust and sand by pycnometer method, moisture content of sand and stone dust by oven drying method, normal consistency of cement, and initial setting time of cement, were performed to determine the physical property of concrete. On fresh concrete slump test was preformed to check workability of concrete and after then compressive strength was checked. Thus stone dust is appropriate substitute of fine aggregates in concrete mix for construction. This is great saving in costly material.


. We suggest a new version of the notion of ρ -dilation ( ρ > 0) of an N -tuple A = ( A 1 , . . . , A N ) of bounded linear operators on a common Hilbert space. We say that A belongs to the class C ρ,N if A admits a ρ -dilation for which for each ζ := ( 1 , . . . , ζ N ) in the unit torus T N . For N = 1 this class coincides with the class C ρ of B. Sz.-Nagy and C. Foia¸s. We generalize the known descriptions of C ρ, 1 = C ρ to the case of C ρ,N , N > 1, using so-called Agler kernels. Also, the notion of operator radii w ρ , ρ > 0, is generalized to the case of N -tuples of operators, and to the case of bounded (in a certain strong sense) holomorphic operator-valued functions in the open unit polydisk D N , with preservation of all the most important their properties. Finally, we show that for each ρ > 1 and N > 1 there exists an A = ( A 1 , . . . , A N ) ∈ C ρ,N which is not simultaneously similar to any T = ( T 1 , . . . , T N ) ∈ C 1 ,N , however if A ∈ C ρ,N admits a uniform unitary ρ -dilation then A is simultaneously similar to some T ∈ C 1 ,N .


The Ginzburg-Landau theory is used to study the texture of superfluid /sup 3/He-A in a slab subject to a uniform perpendicular magnetic field and a weak oscillatory hydrodynamic flow. For steady or low-frequency motion, l undergoes synchronous rotation about H; at high frequency, the orbital viscosity suppresses such motion, producing a planar texture. The integrated mass current provides an operational definition of the mean superfluid density; improved calculations agree somewhat better with available experimental data.


The specificity of a speech unit and its two-component structure are revealed. The focus is made on conclusions as the first component and the mechanism of TT production as a communicative act.


On 22 July 2011, a terrible attack by a lone shooter on the Norwegian island of Utoya cost 77 young lives, injured 78 and changed the lives of hundreds forever within 73 min. In the current international context of increased threat, sharing experience about disaster response is crucial. With some exceptions,1–3 many of these studies adopt a deficit-based analysis approach and focus on dysfunctions rather than positive lessons.

In contrast, Brandrud et al 4 adopted an original approach. The group used the conclusions of two official and independent commissions as starting point, namely that the medical response to the incident was particularly well managed. This enabled a ' positive deviance' 5 6 analysis to draw important lessons from this incident.

The authors attempted to gather crucial insights with the help of detailed group interviews and expert review: How did a rural district hospital, Ringerike , that is not a level-1 trauma centre manage a major disaster effectively, despite the fact that its resources were exhausted 40 min after admission of the first patients? What can this outstanding performance teach health professionals in preparation for disaster in any setting, and especially in a non-specialist hospital?

The answers provided by the study are …


Aims and Objectives: The present study was framed with the intention to find the prevalence of psychological stress and aphthous ulcer in school going teenagers of Bhopal district and to find a correlation between the two and also to find a gender predilection for psychological stress and aphthous ulcer. Materials and Methods: The present study is a questionnaire-based study, and the questionnaire was derived from Ministry of Social Security, National Solidarity and Reform Institutions. It is a twenty-item scale with eighteen positive and two negative questions. Eight private and eight government schools were chosen, and the students were asked to fill the questionnaire. Students were divided into four categories depending on the level of stress. Results: Among the study group, 32.4% (382) of males and 46.6% (437) of females suffered from the aphthous. Nearly 84.2% of females and 64.7% males were stressed which was significant. Conclusion: Stress and aphthous have a positive correlation, and therefore, most of them who had ulcers were found to be stressed. It is therefore need of the present academic curriculum to inculcate stress-free environment for a healthy mind in a healthy body.


Pattern formation in a system of reaction-diffusion equations which exhibit both lateral inhibition and excitability is investigated. The system studied is derived from the FitzHugh–Nagumo nerve conduction model. The existence of solitary and periodic stationary wave solutions is proved. Numerical computations show that some of these waves are stable as solutions of the partial differential equations. Further, arguments are given which indicate that these patterns arise as a result of excitability of the system and not as a result of a Turing mechanism.


Through the case study of Shenyang Tiexi New District Strategic Planning, the paper presents a systematic analysis method which separately reviews relevant factors, such as industrial development, spatial structure, urban image and administrational efficiency, from three views - external environment, internal needs and existing capability, to orient the Urban Spatial Expansion.


ABSTRACT Deoxynivalenol (DON) in cereals, produced by Fusarium fungi, cause poisoning in humans and animals. Fusarium infections in cereals are favoured by humid conditions. Host species are susceptible mainly during the anthesis stage. Infections are also positively correlated with a regional history of Fusarium infections, frequent cereal production and non-tillage field management practices. Here, previously developed process-based models based on relative air humidity, rain and temperature conditions, Fusarium sporulation, host phenology and mycelium growth in host tissue were adapted and tested on oats. Model outputs were used to calculate risk indices. Statistical multivariate models, where independent variables were constructed from weather data, were also developed. Regressions of the risk indices obtained against DON concentrations in field experiments on oats in Sweden and Norway 2012–14 had coefficient of determination values (R2) between 0.84 and 0.88. Regressions of the same indices against DON concentrations in oat samples averaged for 11 × 11 km grids in farmers' fields in Sweden 2012–14 resulted in R2 values between 0.27 and 0.41 for randomly selected grids and between 0.31 and 0.62 for grids with average DON concentration above 1000 μg kg–1 grain in the previous year. When data from all three years were evaluated together, a cross-validated statistical partial least squares model resulted in R2 = 0.70 and a standard error of cross-validation (SECV) = 522 μg kg–1 grain for the period 1 April–28 August in the construction of independent variables and R2 = 0.54 and SECV = 647 μg kg–1 grain for 1 April–23 June. Factors that were not accounted for in this study probably explain large parts of the variation in DON among samples and make further model development necessary before these models can be used practically. DON prediction in oats could potentially be improved by combining weather-based risk index outputs with agronomic factors.


A total of approximately 104,000 fungal species can be expected in Yunnan. However, approximately 6000 fungal species have been reported from the province leaving much to be described. This study introduces a new species, Fitzroyomyces xishuangbannaensis sp. nov and a new collection of Fit. cyperacearum from Yunnan province, China. The taxa were characterized based on morphological characteristics and combined multi-gene phylogenetic analyses. Both maximum likelihood (ML) and Bayesian inference posterior probabilities (PP) were conducted for combined LSU, ITS and mtSSU sequences data. The new Fitzroyomyces species formed a distinct clade among the extant species of Fitzroyomyces with high statistical supports in the phylogenetic analyses while our new isolate nested together with the corresponding strains of Fit. cyperacearum. A key to Fitzroyomyces species and a synopsis table of morphological characteristics for Fitzroyomyces are provided to support the taxonomic placement.


Mixed-ligand cyanonitrosyl complexes of Mo(lI) of the type [Mo(NO)(CN)J(L)2J. formed by the interaction of pentacyanonitrosylmolybdate(lI) anion with some pyridine derivatives (L), viz., nicotinamide, nicotinic acid hydrazide, isoni cotinic acid hydrazide, 2-benzoylpyridine, ni co tine a nd 2-hydroxy methyl pyridine have been prepared, and the products characterized by elemental anal yses, molar conductances, magnetic measurements, electronic and infrared spectral studies. The IR spectral studies suggest that all the heterocyclic compounds behave as monodentate hg~nds coord inating through the ring nitrogen. Molybdenum (II) has a low-spin {MoNO}4 electron configuration in these diamagneti c complexes which behave as non-electrolytes. Suitable octahedral structures have been proposed for these complexes.


Major adverse cardiovascular events (MACE) are some of the numerous comorbidities associated with psoriasis (PsO) and psoriasis arthritis (PsA). Previous studies addressed the contribution of sufficient anti-inflammatory therapy for PsO and PsA in decreasing MACE incidence [1,2].Assessing the risk of developing MACE in patients with pre-existing PsO treated with different treatment regimens; topical treatment, conventional disease-modifying anti-rheumatic drugs (cDMARDs), and biologic disease-modifying anti-rheumatic drugs (bDMARDs) which had not previously studies sufficiently on real-world data.We conducted a retrospective exploratory study with real-world data using the databases of the third largest Israeli health maintenance organization, 'Meuhedet' which covers approximately 1,300,000 subjects. All patients of 'Muehedat' diagnosed with PsO from January 2000 until January 2020 were included in the analysis. Overall, 61,003 patients with PsO were detected. In addition, each PsO patient was paired with four control subjects by gender, age, and ethnicity (general, Arabic, or Orthodox).We defined PsO and PsA according to physicians' diagnoses. MACE included patients with either cerebral vascular accident (CVA), ischemic heart disease (IHD), or peripheral artery disease (PVD). The date of the MACE incident was defined by the first occurrence of one of the diagnoses.We classified the patients diagnosed with PsA into a separate group; thus, patients were categorized according to their diagnosis (control, PsO or PsA). Furthermore, we analyzed the patients by the most advanced treatment prescribed to the patient; sub-grouped 1- topical therapy, sub-grouped 2 - cDMARDs (methotrexate or sulfasalazine), sub-grouped 3 - bDMARDs (anti-TNF, anti-IL17, or anti-IL12/23 agents) (Table 1).The Incident cases of MACE were analyzed according to the different lines of therapy mentioned above. In addition, Time-dependent Cox proportional hazard models were used to evaluate the adjusted risk of developing MACE by treatment group.287,392 patients were included after exclusion by the defined criteria, contributing a total of 2,997,001 patient-years. Adjusted Cox proportional hazards regression analysis showed that the risk of developing MACE in PsO patients treated with topical treatment and those treated with cDMARDs was significantly higher in comparison to controls (Topical, HR: 1.1, CI: 1.02 - 1.1, p-value: <0.001; cDMARDs, HR: 1.2, CI: 1.0 - 1.5, p-value: 0.05). Yet, the risk of developing MACE in PsO patients treated with bDMARDs was not significantly different compared to controls (HR: 1.1, CI: 0.82 - 1.5, p-value: 0.55). On the contrary, the risk of developing MACE in all treatment groups of PsA patients was found to be significantly higher in comparison to controls (Topical, HR: 1.6, CI: 1.45 - 1.7, p-value: <0.001; cDMARDs, HR: 1.4, CI: 1.2 - 1.6, p-value: <0.001, bDMARDs, HR: 1.6, CI: 1.35 - 1.8, p-value: <0.001) (Figure 1). This analysis was adjusted to gender, body mass index (BMI), age of PsO diagnosis, lifetime diagnosis of diabetes mellitus type 2 (DM2), dyslipidemia, hypertension (HTN), and chronic heart failure (CHF); notably, male gender, higher BMI, older age, DM2, dyslipidemia, HTN, and CHF were all associated with a greater risk of developing MACE.Despite that the psoriasis and arthritis severity is higher in patients treated with bDMARDs treatment compared to those treated with cDMARDs and topical treatment alone, bDMARDs have a protective effect on the risk of developing PsA.[1]Ogdie A, Yu D, Haynes K, Love J, Maliha S, Jiang Y, et al. Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a population-based cohort study. Ann Rheum Dis 2015;74:326–32.[2]Ogdie A, Haynes K, Troxel AB, Love J, Hennessy S, Choi H, et al. Risk of mortality in patients with psoriatic arthritis, rheumatoid arthritis and psoriasis: a longitudinal cohort study. Ann Rheum Dis 2014;73:149–53.Figure 1.NIL.None Declared.


On Aug. 21, 1903, Mr. Henry A. Blake,1Governor of Hongkong, addressed a communication to the Secretary of State for the Colonies, entitled "Bubonic Plague in Hongkong; Memorandum by His Excellency the Governor, on the Result of the Treatment of Patients in Their Own Houses and in Local Hospitals During the Epidemic of 1903." The writer of the memorandum makes some very startling assertions as to the danger of the spread of plague by animals of the most varied kinds and also comes to the amazing conclusion that there existed in Hongkong during the period of time intervening between June 23 and July 10, 1903, between 8,000 and 9,000 or more cases among the native population, in which plague bacilli existed in the circulating blood in spite of the absence of all clinical symptoms of the disease. The Governor calls this condition "latent plague" and considers it a potent factor


C ancer is a chronic disease. The average middle-aged male with cancer has a better chance for a 5-year survival rate than if he were a victim of a heart attack. An emotional aura has grown up about cancer which has hampered intelligent discussion of the disease and proper att itude of those dealing with patients so afflicted. In part, th is may come from the "5-year cure" concept which has been popularized by cancer stat isticians. When this same "5-year survival" concept is applied to emphysema, c irrhosis, pancreatit is and other chronic diseases , the cancer statistics are qu ite competitive. Unfortunately, some of the pain and distress assoc iated with cancer have become overly emphasized so that the patient and his fam ily become fearful of the pain and disability. At the workplace the patient with cancer is often snubbed by his fellow workers and has trouble getting back to work after being sick . He can be denied advancement and opportun ities in the job if there is a history, or even a suspicion of history, of cancer, while a diabet ic , or a person with a myocardial infarcti on, or even an alcoholic, is looked upon as someone who can be rehabil itated and completely indoctri nated into the work force. Today's treatments of cancer, which often include extensive rad iotherapy, rad ical surgery, and prolonged chemotherapy, may also add to the fears of the pat ient, his family, and his fellow workers . Thus it is doubly difficult for a cancer patient, who may already confront problems such as adjusting to a colostomy, to have to face misunderstandings on the part of his confreres. As oncologists , we treat pat ients with cancer as just another disease, both in sp ir it and in kind. I was reminded


A mixed model interpolating monthly precipitation linking between Daymet and PRISM(Parameter-elevation Regression on Independent Slope Model) was proposed. And it was applied from January 2006 to December 2010(during 60 months) using 348-AWS(Automatic Weather Station) and 60-ASOS(Automated Synoptic Observing System) in Korea. The estimated monthly precipitation amount was compared with observed records at total 408 weather stations using the Jackknife validation method. The results indicated that the model reflected sufficiently well the spatial distribution pattern of the monthly precipitation. However, it was underestimated when the maximum precipitation at a target station occurred in the influence circle. This is the systematic error of the model based on a statistical technique and will get solved through the calibration of model parameters.


We aim at using a new texton based texture classification method in the classification of pulmonary emphysema in computed tomography (CT) images of the lungs. Different from conventional computer-aided diagnosis (CAD) pulmonary emphysema classification methods, in this paper, firstly, the dictionary of texton is learned via applying sparse representation(SR) to image patches in the training dataset. Then the SR coefficients of the test images over the dictionary are used to construct the histograms for texture presentations. Finally, classification is performed by using a nearest neighbor classifier with a histogram dissimilarity measure as distance. The proposed approach is tested on 3840 annotated regions of interest consisting of normal tissue and mild, moderate and severe pulmonary emphysema of three subtypes. The performance of the proposed system, with an accuracy of about 88%, is comparably higher than state of the art method based on the basic rotation invariant local binary pattern histograms and the texture classification method based on texton learning by k-means, which performs almost the best among other approaches in the literature.


Evolutionary algorithms can be efficiently used to solve many different problems, without knowing much about the nature of the solution. One of the most appreciated property of these algorithms is simplicity. However, this simplicity causes an unguided nature; superfluous or even invalid individuals may be produced taking valuable time from the algorithm. In this paper a preliminary method is described for avoiding such individuals during the evolution of strings from a context-free language. Our method operates on the derivation trees of the underlying context-free grammar and keeps nevertheless the simplicity and randomness of the evolutionary algorithms. Though the system is designed for context-free languages, the method can be extended to higher level languages, too.


Global socioeconomic inequalities are one of the greatest challenges of the contemporary era since they represent a gruesome fact for the whole of humanity. This article seeks to provide a picture of the current socioeconomic inequalities at the global level and analyze the extent to which they ought to be assessed as unjust. To pursue this aim, the article examines the empirical evidence related to the growth in global socioeconomic inequalities and critically assesses them in light of the principle of redress of morally arbitrary inequalities. The article claims that global socioeconomic inequalities are affected by two relevant problematics in both methodological and normative terms. The empirical analysis demonstrates that there is a widespread methodological nationalism that jeopardizes the discussion on socioeconomic inequalities at the global level while the critical assessment of the socioeconomic inequalities shows that their strong injustice can be defended even against the Rawlsian objections to the principle of redress of morally arbitrary inequalities.


Background: The most typical type of hair loss in men is known as male androgenetic alopecia (MAA). MAA predominantly affects the mid frontal scalp, vertex, and temples in a very consistent way. Hair loss affects self-image and is a significant contributor to anxiety and depression in some men. PRP is described in the literature as a sample of autologous blood obtained by centrifuging whole blood and having platelet concentrations above normal physiologic levels. Its effectiveness is strongly related to the regeneration-promoting effects of locally produced growth factors, which are thought to be composed of more than 30 biologically active proteins. Aims and Objectives: To evaluate the efficacy of platelet-richplasma as monotherapy in androgenetic alopecia in male patients. Materials and methods: A total of 20 male patients with androgenetic alopecia were enrolled in this study. PRP was injected into the scalp of these patients. A total of 6 such sittings were given to each patient at interval of 15 days each, over a total period of3 months. Follow up was taken after 3 months and pre and post treatment response was noted using clinical photographs


This study aims to investigate the complex interaction of different resource sets and capabilities in the process of performance creation within the context of resource-based theory. In order to address this objective, an inductive case study approach that included multiple data collection methods such as in-depth interviews, observation and documentation was utilized. The data that were analyzed through causal network models indicated organizational culture, reputational assets, human capital, business processes and networking capabilities as the most important determinants of firm performance within the context of an emerging market firm case study findings.


DaimerThe aterial ntained in this or any other ACE pblication is rovided for eneral irmation only. It hould not be relied on to ggest a ourse of atment for a rticular ividual or as a bstitute for csultation with ualified ealth pessionals who are miliar with your ividual edical eeds. If you have any althcare elated estions or ncerns, you hould ontact your ysician. ever sregard edical dvice or delay in eeking it ecause of mething you have read in any ACE plication. feedbjointhealth.org wwinthealth.org © ACE lanning & nsulting Inc. June 2017 rthritis nsumer xperts (ACE) oduces its nnual JtHealthTM Mications Guide to nable membatients-at-large to have a maningful cversation with their rhatologist and prmacist bout ailable erapy tions, side ffects and route of adnistration. The mdications listed below are the most mmonly scribed by nadian rhatologists and rthritis ecialists to treat ooarthritis (OA), rumatoid rthritis (RA), axial spyloarthritis which cludes kylosing sndylitis (AS) and nonrographic axial spoloarthritis), venile opathic rthritis (JIA), soriatic rthritis PsA), ooporosis, stemic lupus erematosus (SLE), and sculitis. The irmation in this JtHealthTM Mications Guide is not tended to ggest a ourse of tatment. It is for irmation only. lways speak to your octor efore tarting or opping a mdication. acminophen = ylenol® eneric ames of mications are hown in lower case and the first letter of brand ames is citalized. osages are not ovided as they vary based on isease everity and ividual eed. Only the most mmon and the most erious ossible side ffects are hlighted. eneral irmation on ublic drug plan verage can be found at http://JHReportCard. For rivate drug plan verage, lease ontact your enefits ovider for inrmation. portant notes


Jon W. Finson, Robert Schumann: The Book of Songs. Cambridge, MA: Harvard University Press, 2008. Cloth, xvi, 318 pp., $49.95. ISBN-13 978-0-674-02629-2. www.hup.harvard.edu In the opening paragraph of Robert Schumann: The Book of Songs, Jon Finson serves notices that he intends the volume to supplant The Songs of Robert Schumann by Eric Sams (Bloomington: Indiana University Press, 1993). For many singers and coaches, Sams's text has served as the primary guide to the performance of Schumann's lieder since it first appeared in 1969. Finson seeks to replace the older book with a summation of the most recent scholarship on Schumann's songs, including research that previously has been unavailable in English translation. Finson's underlying premise is that Schumann's songs should be studied according to opus number because the composer was meticulous about how his lieder were arranged for publication. In contrast, Sams studies all of the songs in chronological order of composition. Finson begins with a review of the composer's essays on lieder. Surprisingly, given his dual importance as a lieder composer and music critic, Schumann was not a prolific writer on the subject; however, sufficient literature exists to glean the composer's opinions about the genre. Schumann wrote that song settings do not necessarily stem from personal experience; instead, they are an intensification of a composer's reaction to a poem. Finson borrows the term "polyrhythmic lieder" from Walther Durr, author of Das deutsche Sololied im 19.Jahrhundert: Untersuchung zur Sprache und Musik, who based his paradigm on Nagel, a nineteenth century critic. The polyrhythmic lied is one in which "the sound and sense of the verse, of the melody, and of the accompaniment run sometimes congruently, sometimes separately, but in parallel, sometimes divergently," and it represents Schumann's concept of the ideal song setting. In the case of Schumann, whose literary training was extensive, it is not surprising that a variety of verse elicited responses from him. This lends credence to Finson's belief that the song settings of the Liederjahr-which included the bitter portrayals of romantic love found in Liederkreis (Op. 24) and Dichterliebe (Op. 48), both written in the year of his marriage-were not outright reflections of the composer's personal life, but a recreation of the effect that reading a poem had on him. This differs from Sams's analysis of these songs. Moreover, writes Finson, practical factors influenced Schumann's decision to begin writing lieder in 1840. Songs were in demand by the public, and could be written in less time than larger instrumental works. For Schumann, who was waging a legal battle to wed Clara Wieck, the potential for financial stability from the sale of songs was alluring. A large number of the songs that he wrote in the year of his marriage were sold quickly for lucrative fees. Throughout the text, Finson investigates Schumann's rationale for grouping songs for publication. The way songs were grouped and ordered for publication hinged upon pragmatic as well as artistic elements; songs on two pages, facing verso and recto, were preferable, both for reasons of lower printing cost and the absence of a page turn. Schumann's famed creative burst of 1840 produced a vein of lieder that he mined for publication for the next five years. The later collections, comprised of songs written after 1849, vary from earlier opuses in that the lieder they contain were written in a more coherent span of time. These volumes, according to Finson, reveal that Schumann saw the poetry of different poets suitable for juxtaposition. Moreover, even though Schumann's settings of a particular poet appeared in different publications, the relatively short span of time in which he wrote the songs attests to his focus on one poet at a time. Finally, the songs of the later collections, criticized as being difficult by Schumann's contemporaries, indicate that the lied was becoming material for the concert singer rather than the amateur. …


The main aim of this study was to decrease the weight of mobile transportation robot and to check the optimized shape using topology optimization and structural analysis. The analyses were applied using CAE (Computer Aided Engineering) Software with the methods of topology optimization and structural analysis. In the topology optimization process, the preserved areas were defined for connection and fixing areas. The aim was to decrease the weight of robot structure and lower the energy consumption of the robotic system. After topology optimization, the structural strength analysis was applied to the new optimized structure to check about the strength. The weight of the structure was decreased with the ratio of 20%. In addition to this, the structural strength of the robot was observed similar to the original body with the factor of safety value as three.


Abstract A system for measuring individual broiler feed consumption of chickens is described. The system consisted of modified Chucker quail breeding cages and feeders constructed from milk cartons. The system is inexpensive, ($6.34/bird) has virtually no feed wastage, and requires minimal labor.


Medact's conference held at the Royal College of Surgeons, London, on 22 April 2006, marked the twentieth anniversary of the Chernobyl disaster on 26 April 1986. The fallout from Chernobyl was more than radiobiological. Though initially clouded by a fog of denial and secrecy and compounded by uncertainly and panic, the main facts are nevertheless clear. An uncontrolled nuclear reaction occurred as a result of a risky experiment with safety systems which together with design faults in the reactor caused an unforeseen surge in the fission process. The courage and self-sacrifice of many men and women was awe-inspiring; 'liquidators' such as Dr Manzurova are still serving as human 'guinea-pigs' in a colossal experiment. Sir Dillwyn Williams, Emeritus Professor of Pathology, Cambridge, introduced the conference, saying that the events of 20 years ago, with unquantified low-level exposures to radiation world-wide and from 16,000 to 60,000 possible deaths, needed to be under continuous investigation from independent scientists to try to elicit the 'truth' as far as is humanly possible. The health effects should be followed up for generations; the psychological impact on health is probably greater than that of radiation. Unfortunately both the World Health Organisation and the International Atomic Energy Agency have both 'spun' their conclusions, and the nuclear power lobby has had a big influence on what has been made known. At the time, the response to the disaster was essentially inadequate and un-coordinated, both internationally and nationally, and this was made worse by the subsequent break-up of the Soviet Union.


This paper introduces the development of mobile library, and analyzes its future on the basis of the characteristics of4 G communication technology. In order to give Chinese mobile libraries some reference for construction and development, this paper also states the thinking and enlightenment about mobile library construction under 4G environment.


In this paper, we study the boundedness for a large class of multisublinear operators Tm generated by multilinear Calderón-Zygmund operators and their commutators T b m,i (i = 1, · · · ,m) on the product generalized mixed Morrey spaces M φ1 ~ q1 (R) × · · · × M φm ~ qm (R). We find the sufficient conditions on (φ1, · · · , φm, φ) which ensure the boundedness of the operator Tm from M φ1 ~ q1 (R)× · · ·×M φm ~ qm (R) to M φ ~q (R). Moreover, the sufficient conditions for the boundeness of T b m,i from M φ1 ~ q1 (R) × · · · × M φm ~ qm (R) to M φ ~q (R) are also studied. As applications, we obtain the boundedness for the multi-sublinear maximal operator, the multilinear Calderón-Zygmund operator and their commutators on product generalzied mixed Morrey spaces. Mathematics Subject Classification (2010). Primary 42B20; Secondary 42B25, 42B35.


Expander graphs are graphs that have very few edges and yet are highly connected. I will discuss some properties of expander graphs and some of their uses, both in math and in real life


Extreme heat events (EHEs) are linked to mortality rates, making them an important research subject in both the climate and public health fields. This study evaluated linear trends in EHEs using the U.S. Historical Climatology Network (USHCN), version 2.0, dataset and quantified the longer-term EHE trends across the continental United States (CONUS). The USHCN-daily, version 1, dataset was integrated with the homogenized USHCN-monthly, version 2.0, dataset to create daily data for trend analysis. Time series and estimatedtrendsinmultiplecharacteristicsofEHEs(number,totaldays,meanduration,etc.)werecalculated as were the continental means and spatial maps. The differences between EHEs based on daily maximum temperatures, minimum temperatures, and both minimum and maximum temperatures were explored. To focus on warming and cooling periods, the trends were also estimated separately over thefirst half and second half of the study period (1930‐2010). The results indicated that the trends for different EHE characteristics were coherent (e.g., temporally correlated, similar spatial pattern of trends). Maps indicated negative trends in the interior of the CONUS and positive trends in coastal and southern areas. Continental-scale increases between 1970 and 2010 were mostly offset by the decreases between 1930 and 1970. Several daily maximum (minimum) EHEs near the 1930s (2000s) led to 1930‐2010 trends of daily maximum (minimum) EHEs decreasing (increasing). Last, the results suggest that linear trends depend on which daily temperature extreme is required to exceed the threshold.


This chapter explores relationships between social capital, health and age group drawing a a case study of a housing estate in Hackney, London. It does so by briefly introducing social capital theory, and discussing its utility for exploring processes involved in the relationship between social networks and health and wellbeing and in patterns of health inequalities. It draws upon earlier work involving studies in East London before going on to present the study funded by the Health Development Agency.


Metamaterials are rationally designed artificial materials composed of tailored functional building blocks densely packed into an effective material. While metamaterials historically are primarily thought to be associated with negative index of refraction and invisibility cloaking in electromagnetism or optics, it turns out that the simple metamaterial concept also applies to many other areas of physics namely the thermodynamics, classical mechanics including elastostatics, acoustics, fluid dynamics and elastodynamics, and in principle also to the quantum mechanics. The goal of this thesis is to introduce and evaluate the potential of a hydrodynamic metamaterial cloak for drag reduction of objects in viscous flow. In recent years, the hydrodynamic metamaterial cloak has been created in very low Reynolds number Stokes flow by changing the viscosity tensor distribution in the cloak around the object. In practice, the spatially varying viscosity distribution is achieved by introducing a large number of micro-pillars in the cloak domain. In this thesis, the hydrodynamic cloaks for 2D objects of complex shapes such as airfoil are created by coordinate transformation using the Stokes equations for low Reynolds number flows. First, the viscosity tensor for a circular cylinder cloak is derived by coordinate transformation based on the Stokes equations. Then the viscosity tensors for an elliptic-cylinder cloak and an airfoil cloak are obtained by stretching the circular cylinder cloak. The effect of the


In this article, the relationship between masculinity (andreia) and the ideal of Athenian citizenship is analyzed through the case of the Tyrannicides (Harmodius and Aristogeiton). In opposition to "modernist" readings – influenced by Thucydides – by commentators who see the tyrannicide as an action guided by "private" passion, it will be argued here that the eros that brought Harmodius and Aristogeiton together was not at all concealed in the official public discourse of democracy. Analysis of the imagery surrounding the Tyrannicides will enable us to understand the ideological importance of erotic relations – in particular homosexuality (known as pederasty) – in the maintenance of civic harmony and in the reproduction of the community of citizens.


Time trends of age-standardized rate (ASR) of cancer incidence (ICD-10: C00–C96) were compared among 13 selected cancer registries and ethnic/racial groups in Asia. Data source was the Cancer Incidence in Five Continents Vols IV–IX (year at diagnosis 1973–77, 1978–82, 1983–87, 1988–92, 1993–97 and 1998–2002, respectively). World population was used for age-standardization. Asia was divided following three areas, Eastern Asia, South-Eastern Asia and South-Central and Western Asia. China and Japan were in Eastern Asia, Philippines, Singapore and Thailand were in South-Eastern Asia and India, Israel and Kuwait were in South-Central and Western Asia. trend from stable a trend till 1993–97 and showed an increasing trend after that. In South-East Asia, the highest ASR after 1990s is Chinese in Singapore followed by Manila in Philippine, in Singapore, Chiang Mai in Thailand and Indian in Singapore. Chinese in Singapore showed a gradual decreasing. In South-Central and Western Asia, Jews in Israel has the remarkably high ASR and it has increased all over observed period. Though Kuwait had the lowest ASR in Asia in 1978–82, its ASR became same as that in India in the recent period (1998–2002).


Introduction. Museum items tend to arouse significant research interest since they make it possible to trace household activities inherent to a certain community, i.e. aspects of life usually overlooked by archival documents. Astrakhan Reserve Museum houses an authentic collection of Buddhist icons examined in the present study. Goals. The paper attempts an analysis of Kalmyk dartsigs (Buddhist icons) as a source for historical and ethnographic research. Materials and methods. The 'Kalmyk' Collection of Astrakhan Reserve Museum numbers over 220 items, including 49 dartsigs. The work analyzes 48 icons, since dartsig 49 is attributed to the modern tradition and has no authentic value. The employed research methods are the historical/genetic, statistical, descriptive, anthropological ones, that of comparative analysis and others. The study is based on an interdisciplinary approach instrumental in providing multifaceted insights. Results. The shaping of the 'Kalmyk' Collection took place in the prerevolutionary and Soviet periods. The cultural artifacts were collected and donated to the Museum for a number of reasons, the primary one having been that members of Peter the Great Society for the Study of Astrakhan Land were seeking to preserve cultural heritage of peoples to have inhabited the region, lest the latter should be destroyed by the Soviets or lost in the swirl of history. Our comparisons of the current 'Kalmyk' Collection and other sources yield a list of certain Buddhist images that have been lost and are still of great scholarly interest. The well preserved thangkas without passe-partouts had been purposely painted and passed to Peter the Great Society, the poorly preserved ones with traces of soot had once been used in homes of Kalmyk commoners, while the larger and fine images are likely to have been attributes of Buddhist temples or estates of wealthy Kalmyks. The analysis of passe-partouts attests to that Kalmyks were actually handling the icons with utmost veneration, which is evident enough in the qualities of textiles the former were sewn from.


Resumen en: This article analyses, assesses and explains how the European broadcasting policy made by the different EU institutions have contributed to the configu...


Abstract Site of action of the sulfonylureas was investigated by injecting solutions of the compounds into the blood vessels supplying the pancreas and liver. Perfusion of the pancreas via its arterial circulation with a small amount of tolbutamide in the anesthetized dog caused moderate hypoglycemia. Little or no such effect was obtained when the femoral vein or hepatic artery was perfused with the same amount (7 mg. per kilogram of body weight) of the drug. Mean response of the pancreatic artery group was significantly different from those of the femoral vein or hepatic artery groups. The primary importance of the liver in the response was further refuted by a lack of hypoglycemia following injection of carbutamide into the portal vein. Although ligation of the pancreatic ducts failed to prevent the hypoglycemic response to sulfonylurea introduced into the pancreatic circulation, no conclusions may be drawn regarding an acinar role because of absence of control information. There was no alteration in morphology of alpha or beta cells following perfusion of the main pancreatic artery with carbutamide. The important literature bearing on the question of the mechanism of action of these compounds is reviewed, and the nature of their influence on the pancreas is discussed. The data support the idea that the sulfonylurea compounds cause a decrease in blood glucose by virtue of their effect on the pancreatic islets. These experiments tend to establish the usefulness of the technique of pancreatic perfusion for estimating the effect of various substances on islet function.


Abstract : The purpose of this document is to present a plan to provide field validation trials of the CCF Assessment Packages. A preliminary review that should focus on the degree to which the assessment packages reflect current Army doctrine is also suggested. The field trials should focus on practical problems in implementing the assessment packages at CTCs, major simulation centers, and home stations. The first section of this document briefly describes the structure and content of the CCF Assessment Packages. The next section describes the plan for review and field trials. The CCF Assessment Packages have been prepared to complement a function-oriented training program at home stations. These packages may be useful for assessing unit performance in simulated combat at the CTCs and other simulation centers. Before they are adopted widely they should be reviewed for doctrinal content (with some attention paid to areas that are in flux and likely to change soon), and for practicality of application in the settings for which they are intended. Field trials in these settings provide the information needed to improve the utility of these packages.


Liang Qichao is a famous thinker,politician,writer and translator in the modem history of China.As he lived in the historical turning period,none of his activities is free from the political environment.He regarded translation as a tool of preaching and teaching,with the hope of enlightening the wisdom of Chinese people by the western thought,and finally to realize the dream of a strong country.Liang's thought of innovating people by translating guided his translation theories and practices which had a great impact on the society then.


As far as the style of Taigor's short stories is concerned, they are featured by the poetic taste. While expounding this feature, the author enforces his argument with the "taste" , a theory in Indian poetry study that the author consults in an attempt to prove that this great writers short stories are closely related not only to the creative principle and theoretical base, but also to poem composition in terms of language and emotion.


The invention relates to a method for detoxicating chromium residues and the comprehensive utilization of the detoxicated chromium residues. The method for detoxicating the chromium residues comprises the following steps of: performing wet ball milling on chromium-containing waste residues to obtain chromium residue powder; adding water into the chromium residue powder to prepare chromium residue slurry; adding acid into the chromium residue slurry to prepare chromium residue slurry solution, and fully stirring the chromium residue slurry solution simultaneously to make the chromium residue slurry immersed in the acid; adding a reducing agent into the immersed chromium residue slurry solution until hexavalent chromium does not exist in the immersed chromium residue slurry solution; curing the chromium residue slurry solution without the hexavalent chromium, and performing solid-liquid separation; and drying and grinding filter residues to obtain the detoxicated chromium residues without the hexavalent chromium. By the method for detoxicating the chromium residues, various hexavalent chromium compounds contained in the chromium residues can be systematically and completely detoxicated and removed, the hexavalent chromium in various produced building material products is comprehensively utilized, and the content of extract is less than 0.1mg/L.


Plants produce a wide variety of phytochemical constituents, which are secondary metabolites and are used in the pharmaceutical industry. 'For centuries, man has effectively used various components of plants or their extracts for the treatment of many communicable and non-communicable diseases, including bacterial infections. In the present study extracts of Cassia auriculata leaf were subjected for antimicrobial activity by well-diffusion method against six bacterial strains namely Malassezia furfur (MTCC 1765), Enterococcus faecalis, Escherichia coli, Aspergillus awamori, Bacillus subtillis (MTCC 441), Proteus vulgaris (MTCC 1771), Candida Albicans, Pseudomonas aeruginosa. The results revealed that the extracts exhibited strong inhibitory activity against all the tested organisms. The antibacterial activity of these extracts is possibly linked to the presence of flavonoids, steroid, saponins and / or tannins. Further studies are needed to determine the precise active principles from Cassia auriculata. The study effort was effort to make a multipurpose herbal Shampoo by using Cassia auriculata linn. The task of this work is, to protect the herbal active biomolecules and certify the activity. The herbal Shampoo was prepared by using Cassia auriculata flower extract, it was prepared by using 70 % ethanol. The resultant extract was analyzed by various chemical tests. The results confirms that both the extract have active biomolecules. Cassia auriculata linn flower extract incorporated into inert Shampoo base then the biological activity and Shampoo evaluation were piloted. The result shows alcoholic extract of Cassia auriculata in herbal Shampoo was better results in all standard parameters.


In this paper, we introduce a scalable model for the aggregate electricity demand of a fleet of electric vehicles, which can provide the right balance between model simplicity and accuracy. The model is based on classification of tasks with similar energy consumption characteristics into a finite number of clusters. The aggregator responsible for scheduling the charge of the vehicles has two goals: 1) to provide a hard QoS guarantee to the vehicles at the lowest possible cost; 2) to offer load or generation following services to the wholesale market. In order to achieve these goals, we combine the scalable demand model we propose with two scheduling mechanisms, a near-optimal and a heuristic technique. The performance of the two mechanisms is compared under a realistic setting in our numerical experiments.


Members of the Maori Battalion returning home on the troopship Dominion Monarch after World War 2, Wellington Harbour, 23 January 1946. Photograph taken by John Pascoe.
Quantity: 1 b&w original negative(s).
Physical Description: Film negative


Objective: To compare the efficacy and safety of risperidone and clozapine in the treatment of refractory schizophrenia. Methods: 60 inpatients with refractory schizophrenia were randomly assigned to receive either risperidone (200~400mg·d~(-1), n=30) or clozapine (4~8mg·d~(-1), n=30) for 16 weeks. The positive and negative syndrome scale (PANSS), global assessment of function (GAF),and treatment emergent symptoms scale (TESS) were comparable for the two treatment groups prior to the therapy and in weeks 1,2,4,8, 12, 16 post therapy. Weshcler memory scales (WMS) and Wisconsin card sorting test(WCST) were used to evaluate cognitive functions prior to and post the treatment. Results: The GAF in both groups was significantly improved at the end of week 4. The PANSS became a significant decrease at the end of week 8. The GAF score in the patients treated with clozapine was significantly lower compared with the one in the resperidone-treated patients (P=0.000) at the end of week 16. The clozapine-treated patients experienced higher TESS scores than the risperidone-treated patients at the end of week 16. Conclusion: The efficacy of both risperidone and clozapine in the treatment of refractory schizophrenia was apparent. Risperidone showed a better safety profile and more advantage in the improvement of cognition functions.


Abstract This article is devoted to the music of Paweł Szymański. The author is convinced that an intertextual reading of his music is the most compelling one. Taking into consideration Szymański's two-level technique she interprets his works by means of categories elaborated in the field of literature: intertextuality exponent, interpretant, and text characterised by intertextual play. In the second part of the article two different works are discussed, the first representing the algorithmic, and the second the improvisational method of composing. The author concludes that these works are deeply rooted in tradition and, at the same time, are modern, as well as original, with the interpretants constituting the major source of their originality.


Abstract Automotive industry is nowadays characterised by a huge diversity of proposed models, a shorter and shorter product's life cycle and an increasing concurrency between generalist builders. Satisfying customers implies improving Quality and reducing Costs and Lead-time. To stay economically competitive in such a context, it is compulsory to use the production system at the best. Optimising locally the production does not ensure a global performance. That is why we propose in this paper a global modelling of French car manufacturer PSA Peugeot Citroen's Supply Chain. Such an approach allows highlighting and evaluating global impacts of local decision-making. Lastly, we will introduce a decision-support tool, dedicated to factory management.


This study investigates the dynamic characteristics of a smart PZT interface mounted on a prestressed anchorage to verify the numerical feasibility of the admittance-based anchor force monitoring technique. Firstly, the admittance-based anchor force monitoring technique through a single-mount PZT interface is outlined. The admittance response of the PZT interface-anchorage system is theoretically derived to show the proof-of-concept of the technique for anchor force monitoring. Secondly, a finite element model corresponding to a well-established experimental model in the literature is constructed. The effect of anchor force is equivalently treated by the contact stiffness and damping parameters at the bottom surface of the anchorage. Thirdly, the admittance and the impedance responses are numerically analyzed and compared with the experimental data to evaluate the accuracy of the numerical modelling technique. Fourthly, the local dynamics of the PZT interface are analyzed by modal analysis to determine vibration modes that are sensitive to the change in the contact stiffness (i.e., representing the anchor force). Finally, the admittance responses corresponding to the sensitive vibration modes are numerically analyzed under the change in the contact stiffness. The frequency shift and the admittance change are quantified by statistical damage indices to verify the numerical feasibility of the anchor force monitoring technique via the smart PZT interface. The study is expected to provide a reference numerical model for the design of the single-point mount PZT interface.


A great important improvement has been happened on the structures,materials and applicable standards of the principal parts such as bolster and side frame so as to meet the demands to speed up the railway freight transportation under heavy load and safety as the traditional production workmanship is very hard to satisfy the requirements as set forth in the standards.The paper presents the workmanship of bolster and side frame produced with ester setting of water-glass sand,molding production line and configuration of the equipment complete with the molding line,impact to the workmanship,application and control of the molding materials.Quality defects as shown on solidly density,air holes and cracks are also discussed.


The article analyzes the foreign experience of business entities' venture financing of innovative development and outlines the peculiarities of the functioning of venture funds in Ukraine. It is determined that the activities of venture funds are concentrated in innovative sectors of the economy, characterized by prospects for achieving a high level of profitability, but at the same time - the riskiness of projects. The expediency and effectiveness of venture financing in advancing along the way of building a knowledge economy is substantiated. It is proved that this form of financing is characterized by increased risk, which is compensated by the probability of obtaining a higher rate of return than by alternative investments. In addition, the article proposes specific target recommendations on ways and means of improving the efficiency of innovative development in the context of both direct support aimed at business entities and indirect ones, which is carried out through the formation of infrastructure support.


Objective: Impaired arterial distensibility has been described in the early stage of hypertension. The present study was undertaken to investigate the evolution of parameters of arterial distensibility in young-to-middle-age stage 1 hypertensives and to identify predictors of adverse outcome. Design and Methods: We studied 124 untreated subjects (age = 39.5 ± 10.3 years, blood pressure (BP) = 136.2 ± 12.2/85.3 ± 7.9 mmHg) followed for 6 years and 68 normotensive controls. Patients were treated with non-pharmacological measures until they developed hypertension needing drug therapy. To obtain a measure of large artery (C1) and small artery (C2) compliance, radial arterial pulse waves were recorded with a tonometer sensor array (HDI CR2000 device) at baseline and study end. Pulse wave velocity (PWV) and the augmentation index (AI) were obtained with the Specaway DAT system. Results: At baseline, all distensibility indices were impaired in the hypertensives compared to the normotensives (p < 0.001 for C1 and AI, p = 0.001 for C2, p = 0.006 for PWV). Sixty-three patients needed antihypertensive treatment. BP decreased by 4.7/1.9 mmHg (p < 0.001/ = 0.03) in the whole group. Final BP was 134.0 ± 11.3/80.4 ± 7.3 mmHg in the subjects still untreated and 131.7 ± 11.8/79.3 ± 7.6 mmHg in the treated patients (all n.s.). C1 increased by 2.0 ml/mmHgx10 (95%CI,1.1–4.4,p < 0.001) whereas C2,AI and PWV remained unchanged. In regression analyses including sex, age, smoking, alcohol and coffee use, physical activity, parental hypertension, antihypertensive drug treatment(yes/no), height, baseline and final body mass, and the baseline distensibility parameter, baseline BP and spontaneous or drug induced changes in BP were main determinants of changes in C1 (both p < 0.001) and AI (p = 0.03 and = 0.04). The other main determinant of changes in the parameters of distensibility was heart rate measured at baseline (p < 0.001 for C1) or final assessment (p < 0.001 for C1 and p = 0.002 for PWV). Conclusions: BP reduction in the early stage of hypertension obtained with non-pharmacological measures and/or drug therapy can improve large artery compliance in the long term. However, if heart rate remains elevated a worsening of arterial distensibility can occur despite good BP control.


Zirconocene-mediated multicomponent coupling of silicon-tethered diynes, nitriles, and isocyanides results in the formation 5-azaindoles and dihydropyrrolo[3,2-c]azepines in dependence of the amount of isocyanides used.


Introduction The BOLD-contrast mechanism arises from the change of blood oxygenation during cortical activation as a consequence of the increased arterial blood supply, which is most likely due to the increased oxygen demand. It has been originally suggested for the observation of neuronal activation (1). Recently it could be demonstrated, that changes in blood oxygen level can also be used for the observation of myocardial perfusion. In skeletal muscles an increase in perfusion as been observed by Frank using arterial spin label (ASL) techniques (2). The purpose of this study was to demonstrate, whether a BOLD-effect arises during muscle exercise and to assess its temporal signature.


This paper explores the relationship between public opinion data and the consequent policy decisions enacted by the federal government. Specifically, it will examine President Trump's policy implementations regarding the United States' role in foreign affairs. Multiple public opinion polls, both domestic and international, will be utilized throughout to establish an understanding of the public's complex views of this role. Antecedent to this, however, the nature of public opinion will be reviewed by providing a definition for public opinion, examining the various influences throughout one's life, evaluating the criticisms and problems associated with it, and understanding how it ultimately relates to policy making. Significant policy decisions executed by President Trump will be discussed, including the Paris Agreement, North American Free Trade Agreement (NAFTA), and Iran nuclear deal. His continually developing relationships with nations such as Russia, North Korea, and China will also be examined. Notable legal cases involving executive orders issued by President Trump will be assessed, namely the "Travel Ban," family separations, and the Flores Settlement Agreement (FSA). Through in-depth analysis, the paper will illustrate that public opinion, especially among American citizens, does not significantly affect President Trump's decision making when leading the United States in world affairs.


Leptomeningeal amyloidosis is a rare form of amyloid-osis caused by a limited spectrum of mutations in the transthyretin gene (TTR), including the mutation in which threonine replaces alanine at codon 25. We describe the case of a patient with the A25T TTR variant. Only one report of such a case exists in published literature. The patient was a 53-year-old woman with a 4-year history of progressive symptoms of vertigo, paraparesis, and ataxic gait. One month before, she had experienced sudden neurosensory hearing loss. A neurological examination revealed normal higher functions and right-sided hypoacu-sia. Deep tendon reflexes were present and generalised, with intact bilateral extensor plantar reflexes. We found moderate paresis of the right leg with tactile hypoaes-thesia and hypopalaesthesia in both legs. Ataxic gait was also present. The CSF study revealed hyperproteinaemia (177 mg/dL) and xanthochromia. The electromyography study ruled out peripheral neuropathy. Cranial and spinal cord magnetic resonance imaging revealed superficial siderosis in the left sylvian fissure and signs of chronic bleed in CSF (Fig. 1). Both studies found thickened meninges with gadolinium uptake (see Fig. 1). The meningeal biopsy revealed abundant interstitial and perivascular amyloid deposits that were positive for TTR (see Fig. 1). A genetic study confirmed presence of the A25T TTR mutation. The patient had two healthy children who declined to undergo a genetic study. The patient's mother had died of an undiag-nosed disease with similar symptoms at the age of 60. The patient did not undergo studies to rule out the diagnosis of amyloidosis. Leptomeningeal amyloidosis associated with TTR mutations is a rare but fatal form of amyloidosis. The A25T TTR mutation found in our patient was previously reported in a Japanese patient who also developed superficial sidero-sis and died due to multiple intracranial haemorrhages. The autopsy confirmed selective amyloid deposition in the leptomeninges. Our patient presented both clinical signs and radiological findings compatible with superficial siderosis. Superficial siderosis of the central nervous system is caused by haemosiderin deposition in the leptomeninges and the surface of the brain. These deposits are the result of continuous or recurrent bleeding in the subarachnoid space which are due to multiple causes. 3 This presentation was described in the published case of A25T TTR mutation, as well as in other cases of familial amyloidosis in which deposition predominantly affects the meninges. 4,5 As a whole, these data stress the importance of considering leptomeningeal amyloidosis as an infrequent cause of …


An example of determining the list of personal protective equipment and flushing agents for an electric and gas welder is considered, taking into account the risk-oriented approach in accordance with the Uniform standards for issuing personal protective equipment and flushing agents. An analysis is also being made of the sufficiency of providing personal protective equipment for an electric and gas welder of LLC Gazprom UGS after the entry into force of the order approving the Uniform standards for issuing personal protective equipment and washing agents. In the course of the study the hazards were identified, and occupational risks were assessed using the Fine-Kinney method for the workplace of an electric and gas welder at LLC Gazprom UGS. Based on the results of the assessment of the occupational risks, a list of personal protective equipment was determined that is required to provide an electric and gas welder in accordance with the Uniform standards for issuing personal protective equipment and washing agents. A comparative analysis of the current norms for the issuance of protective equipment to an electric and gas welder at LLC Gazprom UGS, and the list of protective equipment required to ensure it in accordance with the Uniform Standards for the issuance of personal protective equipment and washing agents showed no significant differences. However, this study showed that the use of a risk-oriented approach to providing workers with personal protective equipment will allow identifying hazards at a particular workplace and selecting more effective protective equipment based on the results of a special assessment of working conditions and occupational risk assessment.


There are 20 SAE technical papers featured in this book. The papers, originally published in 2009 and 2010, show how the mobility industry is developing greener products and being responsive to new standards and legal requirements. The papers cover a wide range of subjects including powertrain electrification, alternate fuels, emission standards and remediation strategies, nanotechnology, sustainability, in-vehicle networking, and how various countries are handling the "green challenge".


Three rice varieties of Akibare (japonica), Milyang 30 (indica) and Taebaeg (indica) were investigated for their changes in sensory and physical qualities of cooked rites during storage at the temperature range of 4℃ and 70℃ for 25 hours. The qualities studied were sensory attributes of texture which were evaluated by multiple comparison method and physical characteristics of texture measured using with rheometer. Physical properties of hardness, adhesiveness and elasticity of cooked rites were found to be different among the rice varieties and were affected by storage conditions. Higher values in hardness and elasticity and lower values in adhesiveness were measured for cooked rites of Akibare immidiately after cooking. Those physical values were changed by a steady decrease in hardness and elasticity and increase in adhesiveness during storage for 25 hours. Correlations between sensory and physical characteristics of texture was found a significant relationships between gumrniness and hardness (r=0.696), gumminess and adhesiveness (r=-0.800) and gumminess and elasticity (r=0.806).


Since 1995, a network of municipal wells in Iowa, representing all major aquifer types (alluvial, bedrock/karst region, glacial drift, bedrock/nonkarst region), has been repeatedly sampled for a broad suite of herbicide compounds yielding one of the most comprehensive statewide databases of such compounds currently available in the United States. This dataset is ideal for documenting the insight that herbicide degradates provide to the spatial and temporal distribution of herbicides in ground water.


Background: Before onset of labour if premature rupture of membranes occurs, then it is called premature rupture of membranes. This study was conducted to evaluate the maternal and perinatal outcomes in term PROM cases. Materials and methods: This was a prospective study which was conducted during May 2015 to June 2016, on 75 cases of rupture of membranes spontaneously after 37 completed weeks who were admitted in department of obstetrics and gynaecology, Osmania Medical College, Hyderabad. Results: History of term PROM was seen in 15% of the patients, History of abortion was seen in 12% of the patients and history of preterm PROM was observed in 7% of patients. When risk factors and PROM were compared, anaemia was 20%, UTI was 10%, lower genital infections were 8%, cervical stich was 2%, mal-presentations were 4%, hydramnias were 4% and there were no risk factors in 27% of the patients. Favourable bishop score was observed 30 patients undergoing vaginal delivery, 10 in LSCS, and unfavourable bishop score was observed in 20 patients undergoing vaginal delivery, 9 in LSCS. Number of cases in maternal morbidity was highest in > 24 hours i.e. 26.7%, perinatal morbidity cases were highest in 12-24 hours i.e. 30% and mortality among perinatal cases were 5% in 12-24 hours and >24 hours of PROM. Conclusion: This study concluded that premature rupture of membranes incidence was higher in women of unbooked cases and in those with previous history of abortions and premature rupture of membranes. The concomitant increase in incidence of maternal morbidity and perinatal morbidity and mortality with an increase in the duration of labour and delivery and thus rate of caesarean delivery was increased. Jalli Padmaja, Kuthadi Swarupa. Maternal and Perinatal Outcome in Premature Rupture of Membranes at Term Pregnancy. IAIM, 2018; 5(4): 87-91.


This paper introduces a new approach to the problem of direct illumination in physically-based rendering of 3D scenes using illumination maps captured from real environments. We developed a system that takes advantage of the best features of the current solutions to the problem: namely, the approximation of illumination maps through directional lights; and stochastic sampling of the light maps. Our framework is flexible and can be used with most rendering programs.


Literary appreciation is the ability to understand patterns of literature and literary devices, for example symbols and characterization in a text, as well as appreciate the text as a form of art. ...


A graphoanalytical method for the equivalent control air gap is described. The method analyses the operation of the amplifier-servomotor at standstill, establishing an expression for the starting torque. The operating principle of the amplifier servomotor is briefly outlined. It is shown that this new element has a high power gain, so that it can be controlled by d.c. signals from input transducers (photodiodes, thermistors etc.), the direction of rotation depending on the direction of the control signal. This leads to considerable simplification of the automatic control system, eliminating the amplifier, the d.c./a.c. convertors and their supply cells. A comparison is made between the results of the theoretical analysis and experimental results.


Abstract For the waste antimony-uranium composite oxide catalyst, the chlorination of antimony and its volatilization treatment were proposed, and evaluated using hydrogen chloride gas at 873–1173 K. During the treatment, the weight loss of the composite oxide sample, which resulted from the volatilization of antimony, was confirmed. An X-ray diffraction analysis showed that uranium oxide, U3O8, was formed during the reaction. After the treatment at 1173 K for 1 h, almost all the uranium contained in the waste catalyst was dissolved by a 3 M nitric acid solution at 353 K within 10 min, although that of the non-treated catalyst was less than 0.1%. It was found that the chlorination and volatilization treatment was effective to separate antimony from the composite oxide catalyst and change uranium into its removable form.


A 73 year old woman is brought by her daughter with a one year history of worsening forgetfulness. She lives on her own and has been knocking on neighbours' doors in the middle of the night saying she needs to go shopping.

History —Gather as much detail about the forgetfulness as possible from the patient and her daughter. When did it begin? How was it noticed? What does she forget? Is it getting worse? Does she have insight? Does she misidentify people? Does she have difficulty in looking after herself? Is she incontinent? Does she remember to take her medications? Is she anxious or depressed? Is she eating and drinking enough? Is she paying her bills? Does she have any major medical problems such as stroke, transient ischaemic attack, diabetes mellitus, Parkinson's disease? Does she have any risk factors for cerebrovascular disease? Does she smoke or drink alcohol excessively? What medication is she taking? A more detailed assessment may be carried out at a later …


This publication is a research about the phenomenon of creative industries development in Bandung city that growing quite rapidly, but no one has create it in the short feature programs, especially in social media. This content deliver the audience closer to a shorter and clearer story, yet remains informative and entertaining. During this time the production in the video content is rarely done, but still do not have a clear concept as a form of program especially for social media. Consumption on the internet and social media in particular should be used as a medium for information and entertainment, especially the development of creative industries. This study aims to find out how to package the creative industry as a short feature especially for social media. In addition, this research is also expected to promote the creative industry in the Bandung city because the spread of information through social media is easy and fast. This research is a qualitative research with case study approach. The focus of this research is specific to some creative industries in Bandung city in 2018. Audio visual which used as research material are some short feature programs of several international television works in social media. The results of this research show that the packaging of short feature is more informative and entertaining. In addition to its short duration, the information conveyed is more dense and clear. With the medium using social media then the information will be easily accessed whenever and wherever. Packaging information and entertainment in short feature can raise the creative industry in the Bandung city because of the shape and ease to access it. It is expected that short feature concept can be one of the solutions for the improvement of creative industries in Bandung city.


Polyhydroxy compounds and their properties are important in many areas of chemistry and biochemistry. Their polar nature and ability to participate in hydrogen bonding give them a high affinity for water and other polar solvents. Erythritol [(CH2OH) (CHOH)2(CH2OH), CAS No.149-32-6], xylitol and sorbitol are important natural polyols in food and pharmaceutical applications, as they are increasingly used to provide sweetness to various products or replace sugar in confectionery [1–4]. Erythritol's molecular formula is C4H10O4 with molar mass of 122.12 g mol –1 and structural formula as follows:


A generalised urn model is presented in this paper. The urn contains L different types of balls and its replacement policy depends on both an urn function and a random environment. We consider the L-dimensional stochastic process {X n } that represents the proportion of balls of each type in the urn after each replacement. This process can be expressed as a stochastic recurrent equation that fits a Robbins-Monro scheme. Since the process evolves in the (L − 1)-simplex, the stability of the solutions of the ordinary differential equation associated to the Robbins-Monro scheme can be studied by means of differential algebraic equations (DAE). This approach provides a method to obtain strong laws for the process {X n } that can be applied even when the number of actions is greater than the number of types of balls and when the total amount of balls added in each step is random.


Job performance of the employees is one of the central constructs which plays a crucial role in achieving organizational performance. The concept of psychological capital (PsyCap) has given much attention in the recent past as a new approach to enhance the job performance of the employees. However, the extent of the impact between PsyCap and job performance has not been investigated in Sri Lankan context. Therefore, the purpose of this study was to investigate the impact of PsyCap of employees on their job performance in the banking sector in Sri Lanka.The data were randomly collected from a sample of 176 managers and 357 non-managerial employees in the banking sector in Sri Lanka. A questionnaire was administered among the employees to measure their PsyCap and job performance. The collected data were analyzed using correlation coefficient and regression analysis. The results of the study indicated that PsyCap had significantly and positively correlated with job performance. Therefore it is recommended to improve the overall employees' PsyCap in order to increase employees' job performance.


The prevalence of scarlet fever, which on the long periodic wave should show a tendency to decrease at this season of the year, continues, 330 cases being recorded compared with 223 a year ago. The incidence of diphtheria is less although it is not being reduced to the extent desirable, if a larger proportion of children were immunised. There were 81 cases but no deaths. Acute respiratory diseases still remain at a relatively low level and the number of deaths, 38, is considerably below the 70 recorded a year ago following the long spell of very cold severe weather. Cases of pulmonary tuberculosis are slightly fewer and non-pulmonary forms were registered on only 33 occasions against 49 in 1946. The number of deaths for mon-pulmonary disease is also down, 23 against 30. The prevalence of measles which has been present throughout the winter months, but not on a very heavy scale, is showing definite evidence of fading out for there were only 56 cases during April compared with 139 in March. The mortality has not been heavy. Cliickenpox still remains prevalent. The birth rate, 24.5, is higher than in March but definitely below the high rate of 27.5 a year ago. For the reasons stated above, the death rate is lower, 13.3 against 14.4, for the deaths from bronchitis, etc., are fewer. The infant mortality rate, 65, is considerably below the rate of 156 a year ago, largely because of the reduction in the mortality from diarrhoeal diseases and respiratory conditions.


Purpose
The purpose of this paper is to provide an insight and to solve numerically the identification of timewise terms and free boundaries coefficient appearing in the heat equation from over-determination conditions.

Design/methodology/approach
The formulated coefficient identification problem is inverse and ill-posed, and therefore, to obtain a stable solution, a nonlinear Tikhonov regularization least-squares approach is used. For the numerical discretization, the finite difference method combined with a regularized nonlinear minimization is performed using the MATLAB subroutine lsqnonlin.

Findings
The numerical results presented for two examples show the efficiency of the computational method and the accuracy and stability of the numerical solution even in the presence of noise in the input data.

Research limitations/implications
The mathematical formulation is restricted to identify coefficients in unknown components dependent on time, and this may be considered as a research limitation. However, there is no research implication to overcome this, as the known input data is also limited to single temperature in heat equation with Stefan conditions, and the first- and second-order heat moments measurements at a particular time location.

Practical implications
As noisy data are inverted, the study models real situations in which practical measurements are inherently contaminated with noise.

Social implications
The identification of the timewise terms and free boundaries will be of great interest in the heat transfer community and related fluid flow applications.

Originality/value
The current investigation advances previous studies, which assumed that the coefficient multiplying the lower order temperature term depends on time. The knowledge of this physical property coefficient is very important in heat transfer and fluid flow. The originality lies in the insight gained by performing for the numerical simulations of inversion to find the timewise terms and free boundaries coefficient dependent on time in the heat equation from noisy measurements.


: Flexible & scalable services are offered by Cloud services. Mobile applications are enabled by Mobile Cloud Computing for getting powered, built, & hosted with the use of cloud resources. Mobile devices were used for making calls only a few years back but today a lot of applications can be run on mobile devices. Mobile phone would be smart phone which will suit main platform of computing for client. Yet there are many problems like computation time ,battery life etc which resists implementing applications. These applications are computation intensive. It the areas of a typical mobile cloud computing will be investigated in this paper. These are responsible for notable amount of power dissipation.


Classification is the most widely applied machine learning problem today, with implementations in face recognition, flower classification, clustering, and other fields. The goal of this paper is to organize and identify a set of data objects. The study employs K-nearest neighbors, decision tree (j48), and random forest algorithms, and then compares their performance using the IRIS dataset. The results of the comparison analysis showed that the K-nearest neighbors outperformed the other classifiers. Also, the random forest classifier worked better than the decision tree (j48). Finally, the best result obtained by this study is 100% and there is no error rate for the classifier that was obtained. Keywords—Data Mining, Classification, Decision Tree, Random Forest, K-nearest neighbors


 Abstract — Introduction localized gastric lymphoma can be a unique venue in the absence of peripheral lymph adenopathy and mediastinal disorders , and pathological elements in the blood or bone marrow. Represents 4 % of all gastric cancers , most frequently in Western countries in relation to the common intestinal disease that promotes stimulation of the lymphatic tissue The purpose of this study in relation to the observed clinical case is to expose current trends Materials and Methods woman of 70 with a dispetica painful symptoms for two years, heartburn nausea vomiting, melena 8 months ago with 12 kg weight loss , therapy with omeprazole without any alteration effectiveness EUS noted hyperechoic ultrasound interesting all the layers , that did not exceed the serosa . , there are also numerous formations lymph node increased volume of various sizes (2.5 cm max) Histological examination deposed for NH diffuse gastric lymphoma immunophenotype T, immunoreactivity of neoplastic cells for CD3 and CLA absence positivity for cytokeratin and CD79 , high proliferative index .Results In the therapeutic treatment of gastric lymphomas surgery plays an important role , since it allows a radical therapy in localized and a reduction of tumor burden in advanced malignancies facilitating subsequent therapies ( chemotherapy and radiotherapy ) % surgical resection offers a better survival distance when it is curative but palliative resections in the 5-year survival ranges from 25 % -35 % and is closely related to the stage of the disease.Discussion prognosis can therefore be determined in relation to the examination istiopatologico which provides feedback of parameters such as the size , depth of invasion tissue , nodal status cytopathological examination that has a diagnostic accuracy that oscillates between 35-80 % in depending on the method used Conclusion The therapeutic strategy with the purpose of healing gastric lymphoma is fundamentally tied II.della stage I tumor disease in the early stages surgery alone get an index


Seacliff erosion plagues the coastline of northern San Diego County, California through both marine and subaerial processes. Heavy development on seacliffs and the economic value of beaches in San Diego County, California place a heavy emphasis on maintaining a healthy and safe beach. This paper illustrates the development of a rapid response program to study and document seacliff erosional processes utilizing a terrestrial LIght Detection And Ranging (LIDAR) system in combination with interactive visualization techniques to publically present this research. One of the cliff failures currently being studied as part of this rapid response program is described in this paper to demonstrate the insights that can be gained by observing the temporal change of a failure mass using frequent site monitoring.


Smart governance systems have different needs depending on the type of organization, which, together with their inherent complexity, make them difficult to configure. However, we have not found solutions that facilitate the configuration of these systems of great interest in the public sector. We propose a configurability solution compounds of a software framework-based multi-level configuration architecture, and a feature model (FM) to represent the variability in a compact way through the configuration of the different levels of the same software. Thus, the FM we present allows for obtaining a line of customized services for different organizations. On a first level, the variability of the typical collaboration processes is managed, on a second level the different collaboration models are handled, and on a third and fourth level the general smart governance system is configured, and the one adapted to the specific needs of the organization. In this way, while facilitating configuration, a high degree of accuracy is achieved regarding the specific and varying needs of the different stakeholders.


Standards and certification systems have gained importance in facilitating sustainable development processes in global production and consumption networks. However, they are mainly developed in the Global North while actors from developing countries mostly remain passive standard takers. Currently, the majority of standards are primarily resource-oriented, while social criteria are less integrated. The result is a lack of acceptance due to low levels of embeddedness. Which requirements standards have to fulfill in order to facilitate a sustainable development is still widely unanswered. The paper intends to make mainly a conceptual contribution to the evolutionary trajectories of sustainable standards, which explicitly include the social dimension. Conceptually, neo-institutional approaches in organizational theory, focusing on institution building, and the research on innovation and knowledge dynamics are combined. Empirically, the evolutionary trajectory of the sustainability standard Fair Trade in Tourism South Africa (FTTSA) (since 2013 Fair Trade in Tourism FTT) is analysed from a transnational, knowledge-based perspective, based on 63 interviews conducted with different actor groups.


Destructive changes in the bones are rarely observed in daily practice of pediatric orthopedic surgeons. Clinical and X-ray signs of destructive changes in the bone tissue are characteristic of tumoral, infectious, and inflammatory damages of bones. These signs do not always correspond to a specific disease, and differential diagnostics without histological evaluation is difficult. This is especially true for tumors of the sternum, 85% of which are malignant. Two rare clinical cases of primary malignant sternal neoplastic lesions in pediatric patients, and a detailed analysis of their clinical, radiologic, and morphologic data are presented. The importance of early histological verification for determining the choice of treatment is demonstrated. A short literature review is also presented.


In order to suit for higher requirement of power capacitor's measurement,control and protection relay,a new type integration of protection relay and RTU has been researched based on new hardware and software development platform.The new device can better realize substation automation and widely share information each other.It provides not only perfect and reliable protection but also measurement,control and seamless network communications,and record abundantly running information and fault information.The field operation also validates that the new device is reliable and superiority.