In a newly discovered field in the south east of Abu Dhabi, ten Thammama reservoirs were penetrated using a single well and how accurate an understanding of a reservoir and the uncertainties remaining can be assessed by a single well penetrating an accumulation of Hydrocarbon is a frequent question for companies planning to develop new, small reservoirs. The answer depends on how much data the single well got and the other information available about the reservoir and analogue reservoirs. When it comes to Modelling a reservoir that has only been pierced by one well, the assurance on the robustness of the available information is necessary in order to identify gaps and areas of uncertainty and then seek the means to minimize them.
 X-1 well drilled at the Crest of the structure and the location defined by utilizing leatest 3D seismic cube and the total depth 11500 ft RTKB. It was penetrated in the Lower Cretaceous sequence including ten reservoirs which are trapped by 4way dip closure. All the main reservoirs were tested in X-1 well and produced with an oil rate of 370 - 4,370 BOPD (30° - 32° API)
 An analytical "Lambda" Saturation Height Function was developed and implemented in order to overcome the absence of MICP data for initialization stage of Dynamic Modelling. Numerous choices made to develop a family of models that represents the range of reservoir possibilities. Uncertainty analysis including Analog Data from nearby fields utilized to rank the range of outcomes and prioritize obtaining additional information.
 This paper highlight a case study of a three onshore Abu Dhabi discovered structures addressing mitigations toward the challenges to draw a solid conclusion with single well modelling when it comes for development decision by Stakeholders at later stage. Further, the methodology as applied to the case study in this paper, allows identification of the range of outcomes and ranks the additional requirements, ranging from acquiring new Seismic data to drilling new wells, which guide for the next steps to a management decision to develop the reservoir or not.


Aim To investigate the protective effects of quercetin(QCT) treatment on sepsis-induced myocardial depression and explore its mechanism.Methods Male Sprague-Dawley rats were randomized to 1 of 3 treatments: sham operation group,CLP group and CLP pretreatment with QCT(10 rats in each group).Rat sepsis was created by cecal ligation puncture(CLP) operation.Left ventricular(LV) performance was measured at 12 hours following CLP operation by cardiac hemodynamic measurements via a catheter placed through right common carotid artery to the left ventricle.The expression of inducible nitric oxide synthase(iNOS) and the level of nitric oxide(NO),and the activity of iNOS of the myocardium was detected.Results Cardiac function of CLP group rats was depressed markedly by measuring the LVSP,LVEDP,and ±dp/dtmax at 12 hours following CLP operation.iNOS protein of the myocardium was over-expressed,and the level of nitric oxide(NO),the activity of iNOS of the myocardium were also increased.But pretreatment with QCT could weaken all these effects.Conclusion The protective effect of QCT against sepsis-induced myocardial depression is associated with inhibiting iNOS over-expression and activity,and decreasing the availability of myocardial NO.


Sea Buckthorn (Hippophae rhamnoides) a spiny shrub native to Ladakh Region of Jammu and Kashmir, have been found to posses so many medicinal properties from times immoral. From this point of view the antioxidant property of the plant fruit extracts have been analysed by DPPH method. Various plant extracts viz, fruit, leaf and root have been analysed for the antioxidant power determination in which fruit extracts showed highest free radical scavenging activity followed by leaf and root extracts. Among the solvents which have been used, more polar solvents showed highest antioxidant activity than the less polar solvent extracts. The IC50 value of various plant extracts as determined have been found to be 40 for DCM extract of fruit, 38 for Methanolic extract of fruit and 30 for the water extract of fruit. Similarly the leaf extracts posses IC50 value as 51, 47 and 37 respectively for DCM, Methanol and Water extracts. The IC50 values of various root extracts have been found to be 53, 50 and 48 respectively for DCM, Methanol and Water.


The effect of climate change on water resources has been an area of continued research, especially in Australia. Previous studies have suggested significant trends in rainfall, and these are amplified causing larger changes in streamflow. However, most of the previous analysis was based on annual time scales or modelled data and did not account for changes in land cover, which could interact with changes in climate. Climate data and streamflow data between 1970 and 2010 from 13 mostly forested small catchments (<250 km2) in Australia were analysed for trends. Non‐parametric Mann‐Kendall trend analysis, generalized additive mixed modelling and rainfall‐runoff modelling were combined for the analysis. This indicates consistent increases in maximum temperature and varied decreases in rainfall. The streamflow in the studied catchments indicated small decreases in streamflow, which amplified observed trends in the rainfall. In general, overall decreases are much smaller than suggested in earlier research.


of the treatment of 30 patients with bacterial pneumonia. The full investigations done included blood culture (five positive), pneumococcus typing, and sensitivity testing. All the patients recovered, despite the existence of severe complicating conditions in 12 of them. W. J. Martin and his colleagues at the Mayo Clinic5 have treated 34 patients, including two interesting groups. One of these comprised five patients with staphylococcal septicaemia, in four of whom the result was " excellent," though in the fifth treatment had to be abandoned owing to a drug rash superimposed on an original exfoliative bullous lichen planus. The other comprised five patients with staphylococcal enterocolitis following treatment with other antibiotics; all responded to novobiocin. These authors also treated eight cases of urinary infection, five of which were due to Proteus, the least insensitive to this antibiotic of the coliform bacilli, with varied results. The studies of R. L. Nichols and M. Finland6 also included cases of urinary infection, some being due to Bact. coli, which is relatively insensitive to novobiocin, even in an acid medium, as they themselves showed. It seems very doubtful whether the low concentration excreted in the urine could be bactericidal to such an organism. Nichols and Finland's work includes important observations of a kind not referred to in the other papers. They tested the novobiocin sensitivity of organisms isolated during or after treatment and obtained evidence of increased resistance in staphylococci, Proteus, and salivary streptococci. It is not certain whether these were the original strains or the result of selection and substitution, but the presumption is strong that resistance to novobiocin can develop in vivo. How far should the advent of novobiocin and possibly other antistaphylococcal drugs affect policy in the giving of older antibiotics ? Certainly it affords no excuse for indiscriminate use. Our staphylococci are what we make them; the more an antibiotic is given, the more frequent does resistance to it become, and hence the less beneficial is the drug. There is therefore no substitute for wise and discriminating use. On the other hand, it is arguable that for proper indications an antibiotic which has hitherto been the last line of defence against staphylococci might now be given more freely. This is erythromycin, the value of which has been greatly diminished by widespread use in the United States. In Britain, without imposing such restrictions on it as have been thought necessary in New Zealand, we have so far preserved its efficacy almost entirely unimpaired. The official warnings against its unnecessary administration have had a remarkable effect, and the profession seems to have been reluctant to give it except for the strongest indications, despite its advantages over the tetracyclines for the treatment of most coccal infections. No one wants to see staphylococci in this country becoming resistant to erythromycin, even though fresh substitutes for it exist, but our record so far has been so good that we might well ask whether giving it more often is not compatible with maintenance of the present satisfactory position. If local application is avoided, as has been strongly urged by authorities in the United States,7 and if courses of treatment are limited in duration, it may well prove that the fear of acquired bacterial resistance has been excessive. Paradoxically enough, the dangers of this are far greater in hospitals than outside them; hence the general practitioner is entitled to more liberty in the use of antibiotics suffering from this limitation than his colleague working in hospital.


Objective:  To assess the anti-microbial activity of sage oil and hempseed oil against  Streptococcus mutans  and  Candida albicans .  Material and Methods:  The sage oil and hempseed oil in pure extract form were collected from an authorized government organization. The anti-microbial activity from the oils was assessed by Kirby-Bauer disc diffusion method. Standard antibiotics Vancomycin and Fluconazole were taken as a positive control for  Streptococcus mutans  and  Candida albicans,  respectively. The mean zone of inhibition (ZOI) was measured at 24 hours, 48 hours and 72 hours by HI-MEDIAs antibiotic zone scale. One-way Analysis of variance with Tukey's Post Hoc was applied for statistical analysis.  Results: The mean zone of inhibition of sage oil and hempseed oil at 24 hours, 48 hours and 72 hours against  Streptococcus mutans  was (7.0 ± 4.24, 9.1 ± 3.71 and 8.4 ± 3.02) and (0.0, 3.2 ± 0.75, 1.9 ± 1.24) respectively. The zone of inhibition against  Candida albicans  24 hours, 48 hours and 72 hours for sage oil (2.80 ± 1.151, 6.70 ± 1.30 and 6.30 ± 1.44), hempseed oil (0.0, 3.80 ± 0.75, 3.10 ± 0.41). Sage oil presented potential anti-microbial activity against  Streptococcus mutans  and  Candida albicans . Comparing the anti-microbial efficacy, standard antibiotic (Vancomycin/Fluconazole) was more effective than test oils .  Conclusion:  Test oils showed anti-bacterial and anti-fungal activity against  Streptococcus mutans  and  Candida albicans . Among these, sage oil showed efficacy at 24 hours, while hempseed oil did not show any effect at this time point. Further studies are needed to affirm the same and test their efficacy in different forms and concentrations.


In Demand Side Management framework, the models are generally complex, nonlinear, and highly constrained. This study proposes a price/power weighting-based linearization integrating a battery management system for an appliance-scheduling model to overcome constraints handling issues and computational challenges of the metaheuristic algorithms. To this end, the notion of a relative cost is introduced. Simulation results demonstrate that the proposed approach is capable of solving an appliance-scheduling problem, using Mixed Integer Linear Programming, with a shorter run time compared to the result provided by the nonlinear problem solved by genetic algorithm-based while ensuring self-consumption.


The H3PW12O40/ZrO2-WO3 was prepared by impregnation,and characterized by FT-IR and XRD.Cyclohexanone 1,2-propanediol ketal was synthesized from cyclohexanone and 1,2-propanediol by using H3PW12O40/ZrO2-WO3 as the catalyst.The influence factors on the yields of cyclohexanone 1,2-propanediol ketal were investigated.The optimum conditions are that:molar ratio of cyclohexanone and 1,2-propanediol is 1∶1.4,the volume of cyclohexane as the water-carrying agent is 10mL,reaction time is 30minutes,and mass fraction of catalyst to reactants is 0.8%,respectively.The yield of cyclohexanone 1,2-propanediol ketal can reach 88.9% under the optimum conditions.


Information retrieval is the important work for Electronic Commerce. Ontology-based semantic retrieval is a hotspot of current research. In order to achieve fuzzy semantic retrieval, this paper applies a fuzzy ontology framework to information retrieval system in E-Commerce. The framework includes three parts: concepts, properties of concepts and values of properties, in which property's value can be either standard data types or linguistic values of fuzzy concepts. The semantic query expansions are constructed by order relation, equivalence relation, inclusion relation, reversion relation and complement relation between fuzzy concepts defined in linguistic variable ontologies with Resource Description Framework (RDF). The application to retrieve customer, product and supplier information shows that the framework can overcome the localization of other fuzzy ontology models, and this research facilitates the semantic retrieval of information through fuzzy concepts on the Semantic Web.


In the title compound, C13H9N3O2, the aromatic rings are twisted with respect to each other, making a dihedral angle of 49.41 (9)°. The nitro group and the nitrile group are nearly in the plane of the benzonitrile ring, the largest deviation from the plane being 0.123 (1) Å. There is an intramolecular N—H⋯O hydrogen bond forming an S(6) ring. Weak intermolecular C—H⋯O hydrogen bonds link the molecules into a chain parallel to the c axis. Futhermore, slipped π–π interactions between symmetry-related phenyl rings [centroid–centroid distance 3.808 (1) Å, interplanar distance 3.544 (8) Å with an offset of 21.5°] stabilize the structure.


We present computer simulations of anomalous diffusion, $ \sim a t^{1-\delta}$, in two dimensions. The Monte Carlo calculations are in excellent agreement with previous renormalization group calculations. Interestingly, use of a high quality pseudo-random number generator is necessary to observe the anomalous diffusion. A linear-feedback, shift-register method leads to incorrect, ballistic motion of the random walkers.


Lower esophageal sphincter pressures (LESP) are generally measured during esophageal motility studies using multilumen water perfused catheters. Because of the large size of this assembly, gagging occurs, sedation is required and acceptable tracings may not be obtained. We have compared a large catheter assembly (three 1.2 mm single lumen catheters bound together with a 4.0 mm total diameter) with a 1.2 mm single lumen catheter with 1.0 mm side orifice. Triplicate studies were obtained by perfusing the catheters with water at 1.3 cc/min and slowly withdrawing from the stomach to LES. LESP were obtained in 10 fullterm newborns 3 hours after feeding; infants were then sedated and 90 min. later triplicate studies repeated. LESP were as follows:In two patients, gagging prevented the recording of adequate tracings from triple lumen catheters. Our data indicates that LESP can be successfully measured in the unsedated infant using a small single lumen catheter, and that higher pressures are obtained with the single lumen assembly.


21 kinds of non-magneitc steel, already known and newly found by the author, ware taken and subjected to the experiments-(1) Chemical composition, and magnetic stability, (2) Annealing temperature and magnetization, (3) Mechanical properties, (4) Corrosion resistance, (5) Microstructures, (6) Cold workability, (7) Cold working and magnetization, and (8) Annealing of cold worked sample-, and with the results each steel is throughly discussed from the technical view.


The flow field in a new mold with hybrid magnetic fields with combination of alternative and static electromagnetic fields for continuous casting was simulated. The comparison of the results with different static magnetic flux density was conducted. The principle of the new mold was analyzed. The results show that the new technique not only has the advantages of both soft contact EMC (electromagnetic continuous casting) and EMBR (electromagnetic braking) but also overcomes some shortcomings of the two techniques in controlling the meniscus.


Stem cell‐like memory T cells (Tscm), are a newly defined memory T cell subset with characteristics of long life span, consistent self‐renewing, rapid differentiation into effector T cells, and apoptosis resistance. These features indicate that Tscm have great therapeutic or preventive purposes, including being applied in chimeric Ag receptor‐engineered T cells, TCR gene‐modified T cells, and vaccines. However, the little knowledge about Tscm development restrains their applications. Strength and duration of TCR signaling, cytokines and metabolism in the T cells during activation all influence the Tscm development via regulating transcriptional factors and cell signaling pathways. Here, we summarize the molecular and cellular pathways involving Tscm differentiation, and its clinical application for cancer immunotherapy and prevention.


The rate constants, k
 CR
, of ortho–para-positronium conversion reactions promoted by Cr
 III
, Mn
 II
, Co
 II
 and Ni
 II
 complexes have, previously, been correlated with the corresponding delocalization of metal electrons as described by means of the ratio, β, between the interelectronic repulsion parameters in the complex, B, and that in the free gaseous ions, B
 0
. The parameters of the correlation lines have been improved by investigation of another eight conversion reactions. It was confirmed that the k
 CR
 values for β→0 are proportional to the number of unpaired electrons of the metal ions, the newly determined proportionality constant, χ, being 3.0±0.2 dm3 mol
 -1
 ns
 -1
 electron
 -1
 (cf. previous value 3.7±0.6).


Aimed at reducing the amount of coking coal in blending coking and improving the utilization rate of waste plastics,this paper is concerned specifically with an effort to replace a certain proportion of coal and coking coal with waste plastics to perform co-carbonization in 40 kg experimental coke oven,and investigate the law underlying the consequent variation in coke and tar yield and coke strength. The investigation suggests that the replacement of coking coal with waste plastics with a mass fraction of anywhere from 1% to 5% gives rise to the following changes: a decrease in the coke yield,an increase in the tar yield,an initial increase and subsequent decrease in M25,an initial decrease and subsequent increase in M10,and an increase in coke reactivity,but a decrease in relative strength following the reaction; the addition of waste plastics of less than 3% allows the cold strength and hot strength of coke to remain up to the secondary standard of metallurgical coke for the grading index of national metallurgical coke quality. The study may serve as a reference for relative industrial production.


The transition behavior of micro-crystal and non-crystal layer on grinding surface has been revealed by TEM. The situation existing micro-crystal in the degenerating layer has been veri- fied by using methods of both phase analyzing and x-ray diffraction analyzing. And the chemical composition of non-crystal layer has been determined by energy spectrum analyzing. On the basis of the quantitative analysis for the glassiness structure, by applying phase balancing theory in sili- cate physical chemistry, the research has been proved that the degenerating layer of Al2O3 surface is made up of micro-crystals and glassiness compound. Based on these, the physical model of plastic degenerating layer has been established and the fractional mechanism of surface crystal par- ticles has been explained by micro-edge cutting theory.


Chronic back or limb pain is often debilitating and disabling resulting in loss of efficiency, depression, and low self-esteem. Diagnosis usually suggests arthritis or nerve root pathology and patients receive long-term oral analgesics and invasive procedures with little or no relief. Hypothyroidism may present as peripheral neuropathy which may be clinically indistinguishable from entrapment neuropathy as occurs with neural canal stenosis. Muscle cramps, aches, proximal symmetrical muscle weakness, stiffness, polymyositis, and exercise intolerance may be the only presenting symptom indicating hypothyroidism. We present five cases of acute on chronic pain that improved significantly on treatment with thyroxine. Neuromuscular pain may be the only presenting symptom of hypothyroidism. Thyroid profile (TSH, FT3, FT4) and anti-thyroid peroxidase (anti-TPO) antibodies should be screened before subjecting the patient to multiple analgesics and procedures.


drugs. modified release matrix, a sustained film former, and as a agent, and when the cellulose methylcellulose K4 M K4 M), and Eudragit RL-100 copolymers have already been used as excipients of sustained release implant material in dentistry. [4,5] Satranidazole, a novel nitroimidazole possessing a C-N linkage at C2 of the imidazole ring. The drug produces ABSTRACT Periodontal strip is a dental device with very small loading dose for site specific one time continuous delivery of drug. Periodontitis is a of inflammatory disease affecting the tissues surrounding the teeth. Periodontitis involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening and subsequent loss of teeth. This condition is treated using antibacterial agents by oral route. It has been observed that drug administration by this route caused adverse reactions due to high dose. The concept of delivering the drug directly into the periodontal pocket led to the development of local drug delivery systems. This concept gained attention as it requires low dose, produces sustained action and delivers the drug near to or onto the target site. The objective of present study is to formulate and evaluate satranidazole dental strips for use periodontitis. Dental strips were prepared by solvent casting method by using various polymers like, Ethyl cellulose, HPMC K4M, HPC, and Eudragit RL 100 in varying concentrations. The prepared formulations were evaluated for weight variation, thickness, content uniformity, invitro drug release studies. Stability studies were formulated with SF7 containing polymers Ethyl cellulose and HPMC K4M was considered as the best formulation based on invitro drug release of 96.43% in 7 days. The formulation found to be stable over a period of three months stability. Further work to done the antibacterial activity of the developed formulation will help to suggest that satranidazole dental strip provide an alternative for use in periodontitis.


. We study associate and double associate spaces of two-weighted Sobolev spaces of the first order on real half-line and we show that unlike the notion of duality the associativity is divided into two cases which we call "strong" and "weak" ones with the division of the second associativity into four cases. On the way we prove that the Sobolev space of compactly supported functions possess weak associated reflexivity and the double weak-strong associate space is vacuous. The case of power weights was recently characterized by reduction to Ces`aro or Copson type spaces [18].


Any discussion of judges and judging in medieval England must take into account that there were many different courts and many different kinds of judges. In addition to the king's courts, there were county courts, hundred courts, and borough courts, not to mention manorial courts. And there was also an independently functioning system of ecclesiastical courts that had extensive jurisdiction over many matters that we would not think of as religious, such as inheritance, marriage, and defamation. Although the king's courts and the king's judges would eventually assume the preeminent position in the English system of justice, they were only a part of that system, and the decisions of other judges could have a significant impact on the lives of Englishmen of all stripes.


The use of Field Programmable Gate Array (FPGA) devices for designing and prototyping a pager-like device is presented. The device executes the decoding tasks in a system, which also has a transceiver sending information at 1200 bit/s with a FSK modulator and a receiver/demodulator; the RF part operates in the 450 MHz range. The device was intended for "finding" and signaling, by light or sounds, objects such as cars, containers, or medical equipment in large environments. The traditional paging protocol POCSAG has been slightly modified to use minimal resources and provide new characteristics for the specific applications.


Biological innovations played a far more important role in American agricultural development than previously thought. These innovations were essential in allowing farmers to combat pests and diseases, to move the agricultural production into new environments, and to increase farm productivity. Many biological advances, especially those aimed at fighting contagious animal diseases, required unprecedented federal government interventions to overcome the free‐rider problem and to transfer new knowledge into effective public policy. Early USDA animal disease programs significantly increased productivity and trade in the livestock sector and prevented hundreds of thousands of untimely deaths in the United States from food‐borne illnesses by 1940.


In recent years, it begins to be anxious about the warming problem by the increase in carbon dioxide on a scale of the Earth. Actually, this is considered to be also a cause that this year is overly developing of a large-scale typhoon and the direct hit to a Japanese mainland. Inside of such backgrounds, every country in the world is performing the research and development about the new power generation system from various viewpoints in such backgrounds for the amount curtailment of discharge of carbon dioxide. In our country, a target called the amount of domestic wind power of 3000 MW is held up by the 2010 fiscal year. Then, (in this research, by using a control device original whether it is what cannot increase system interconnection more paying attention to a wind power place, stability is improved and comparison and examination is performed. This research shall perform comparison and examination for the ability to carry out which the system interconnection of the wind power place in the future, without causing quality aggravation of electric power by imitating the existing electric utility in a specific area


This dissertation explores the rhetorical concept of ethos as it functions in contemporary online communities, via a case study of one successful online community, MetaFilter.com. A year-long virtual ethnography of MetaFilter demonstrates that understanding ethos as it functions online requires a multilayered definition that accounts for the traditional notion of ethos as vir bonus, the strict Aristotelian conception of ethos as textual element, and the pre-Aristotelian idea of ethos as "gathering place." It also documents the unique strategies employed by digital rhetors to establish and maintain their individual ethos, evaluate the ethos of their interlocutors, and shape the collective ethos of the communities to which they belong. Finally, it argues that ethnographic research in digital environments necessitates a mixed-methods approach for collecting, coding, and analyzing data. This study employs a limited number of quantitative measures and a variety of qualitative measures to analyze four types of data: (1) statistical information from the MetaFilter database (2) archived discussion threads from one of MetaFilter's forums, MetaTalk, (3) survey responses by MetaFilter members, and (4) interviews with the community's moderators. After presenting the study's findings, the dissertation concludes by indentifying four paradoxes manifested on MetaFilter that can help researchers, practitioners, and teachers of digital rhetoric better understand online communities and the essential role of ethos within those communities.


Models of management of the regional innovation development aren't adequate to the strategy of innovative transformation. At the present stage of innovative modernization the uniform methodological approach, working out of the new methodology of management raising its efficiency in questions of maintenance of a development of region is necessary.


For many real-world decision-making problems subject to uncertainty, it may be essential to deal with multiple and often conflicting objectives while taking the decision-makers' risk preferences into account. Conditional value-at-risk (CVaR) is a widely applied risk measure to address risk-averseness of the decision-makers. In this paper, we use the subset-based polyhedral representation of the CVaR to reformulate the bi-objective two-stage stochastic facility location problem presented in Nazemi et al. (2021). We propose an approximate cutting-plane method to deal with this more computationally challenging subset-based formulation. Then, the cutting plane method is embedded into the epsilon-constraint method, the balanced-box method, and a recently developed matheuristic method to address the bi-objective nature of the problem. Our computational results show the effectiveness of the proposed method. Finally, we discuss how incorporating an approximation of the subset-based polyhedral formulation affects the obtained solutions.


THE PURPOSE of this paper is to analyse the complex phenomenon of inter-union rivalry in relation to union behaviour in India and to attempt to identify some of its effects on the Indian trade union movement. The paper begins with a brief account of major developments in the Indian trade-union movement vis-à-vis union rivalry. In the next section an attempt is made to analyse the programmes of four Central Trade Union Organizations on broad social, economic and political issues and their approaches to the problem of trade union unity. This is followed by a brief account of some instances of unity moves. Lastly, some effects of inter-union rivalry on various aspects of trade union movement are traced.


I truly believe that over the next fifty years there will be, as there was in the prior fifty years, an expansion of freedom; an increase in equality. Because here I believe, and I'll conclude with this, that the late Dr. Martin Luther King got it right when he said "The arc of the moral universe is long but it bends towards justice."


There is a passage in Marcellinus' biography of Thucydides (secs. 30-33) about which there has been a great deal of learned discussion. It is not likely that any suggestion about any part of it can be made now which has not already been made by someone. Yet no convincing solution of all the apparent difficulties has been proposed by anyone, and few have agreed on any single interpretation of the passage as a whole. The passage would not be important, and perhaps not very interesting, if it did not contain certain opinions of Cratippus and Zopyrus, who may have lived in the time of Thucydides himself. Dionysius of Halicarnassus says' that Cratippus was a contemporary of Thucydides (ouvPaKgwaoas avcr43). If that is so, then Cratippus' testimony about Thucydides is much more valuable than all the arguments and deductions of later writers about him; consequently, Thucydides died in Thrace, probably by a sudden and violent death, and he was not buried among the "Cimonian monuments" at Athens. That would be interesting, and not without importance in the history of the literature of the ancient Greeks, for the light it would throw on the private life of the greatest historian of them all. But some of the best scholars have believed it quite impossible that Cratippus was a contemporary of Thucydides, and so have thought it necessary to emend the statement of Dionysius of Halicarnassus or to conclude that that uninspired author was mistaken again. The question of the date of Cratippus has acquired a new importance since the publication of the Hellenica Oxyrhynchia in 1908. It seems certain that these fragments belong to a history written between 356 and 346 B.C.2 Some have assigned the work to Cratippus. But if Cratippus lived and wrote in the Hellenistic age, he could not have been the author in question. Personally I believe that Professor


In this section, we have demonstrated the behavior of polyaniline nanofibers (PANI NFs) as silver –PANI NFs nanocomposites (NC) with new physical insights. The synthesis of PANI NFs and PANI nanospheres (NSs) was carried out for different polymerization period and studied their effect on the structure, morphology and electrochemical performance. The HCl doped PANI NFs shows similar properties of silver-PANI NFs NCs. Structural information obtained from XRay diffraction (XRD) along with UltravioletVisible (UV-Vis.), Fourier Transform Infrared Red (FTIR), Raman and Nuclear Magnetic Resonance (NMR) spectroscopy. Morphological study was carried out by Field Emission Scanning Electron Microscopy (FESEM) and High Resolution Transmission Electron (HRTEM) Microscopy.


The article developed an algorithm for calculating the coefficient of the impact of innovations on the growth rate of the final product. This mathematical apparatus is a tool for adequate adjustment of the economic system, taking into account the potential of its innovative development. Next, the problem of predicting the regional final product is solved using the Cobb-Douglas(innovation) model. In the calculations, the values of the parameters are determined by the Gradient method. The result obtained indicates the adequacy of the approach used. In addition, the assumptions and hypotheses put forward in the study create prerequisites for further expanding the amount of knowledge in the field of studying the innovative impact on the economy. The practical significance of the proposed models of innovative development of economic systems lies in the emergence of new opportunities for building the innovation policy of the state.
Keywords: innovation activity, fuzzy model, Gradient method, innovation index


Calcifying odontogenic cyst (COC) is a developmental odontogenic cyst which was first described as a separate entity by Gorlin et al. in 1962. COC characterizing as a cyst and neoplasm accounts for only about 1% of all odontogenic cysts. This unique lesion occurs mostly as intraosseous and rarely as a peripheral variant. Due to its diversified histological presentations and spectrum of variants the pathogenesis and the biological behavior needs to be understood. In this article, we present a case of COC in the maxilla of a 14 year old female with brief discussion.


The permeability of a breakwater core affects the stability of the breakwater armour. No design guidelines are available to account for the effect of a geotextile container core on armour stability. This paper discusses the present knowledge on the effect of core permeability on armour layer stability, both for rock and concrete armour units. Results are presented from project specific model tests on Xbloc armoured breakwaters with geotextile container cores. A prototype case is presented where damage has occurred, which may be attributed to low core permeability. Recommendations are given for the design of breakwaters and seawalls with low permeability cores.


For ages we've been debating about whether or not Emotional intelligence will also be learned. Even EI is contributing 80% of a individuals success we aren't mindful of it. Intelligence(IQ) is a threshold potential for entry degree function. Emotional Intelligence is the sine qua non of management. This the connection between demographic characteristics of the respondents and the extent of emotional intelligence, the influence of Big Five Personality traits towards the level of respondents Emotional Intelligence, the influence of Psychological ownership of respondents towards Emotional Intelligence, the influence of Emotional Intelligence towards job Performance, employees wellbeing and stress tolerance. Performance has been categorized as individual context and Task Oriented.


To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective α1‐adrenoceptor antagonist, alfuzosin (Sanofi‐Aventis, Paris, France) attenuates any erectile dysfunction (ED).


This article examines rural dwellers' perceptions of digital financial services (DFS) to identify which factors may enhance or impede their adoption. The article is based on a survey and follow-up interviews in rural Fijian communities with relatively low income levels. In Fiji, DFS are provided by mobile network operators, either individually or in collaboration with commercial banks. The provision of these services is consistent with policies of the Fijian government and The Reserve Bank of Fiji, which advocate financial inclusion as a means of promoting economic growth and enabling citizens to more efficiently receive remittances and welfare payments. However, the survey findings indicate that DFS uptake is hindered by agents' lack of liquidity and the implicit costs that agents impose on consumers. In addition, consumers tend to fully spend the funds received through mobile money, but fail to use their mobile phones for saving purposes.


Examines the effects of farm residence and farm background on a couples fertility after other variables are controlled as a step in identifying the dynamics of rural-urban fertility differentials. The sample was 5552 couples with husband present drawn from the 1970 National Fertility Survey. An analysis of cavariance of education income and fertility was performed to control for additional factors known to influence fertility. The strongest standardized partial regression coefficient among the covariates is the association between wifes age and fertility followed by wifes ecucation husbands age total family income and husbands education. A 2nd table presents a multiple classification analysis of fertility by farm residence or background race and region with controls for the covariate variables. 5 categories are delineated for the central independent variable of farm residence or background. After controlling for most variables farm residents persist in having the highest fertility followed by couples in which husbands and wives both have farm background. Couples in which only 1 spouse has a farm background show approximately the same level of fertility as nonfarm couples. Findings with respect to race showed that blacks have the highest fertility followed by other nonwhites. The finding that farm resistence or farm background is associated with higher fertility suggests that part of the decline in American fertility is due to a smaller proportion of the population residing on farms or having farm backgrounds.


Background: Heart Failure(HF) might represents the conclusive clinical event of hypertensive disease(HBP) and its complications. Considering its increasing prevalence, HF is an important clinical and economic challenge often needing integrated and specialistic management programs. Purpose: Aim of the present study was to assess the effect of 1 year dedicated and integrated program care,comprehensive of systematic assessment and management,counselling,educational,on progression of NYHA class and rate of hospital admissions in patients with hypertension-related HF. Methods: Patients with history of hypertension and clinical,radiological or echocardiographic evidence of HF have been enrolled in the study. At entry and after 12 months we evaluated: physical signs,NYHA class,LV function(LVEF%),neuro-humoral profile,on-going therapy. Main objective was the number of and hospital admissions after 6–12 months of intensive approach compared with those in the previous 12 months. Results: In a 5 year period we evaluated 438 consecutive HF patients, of which 170(75%) had at least 1 year control (108 M and 62 F,mean age 76 years,range 40–90). At entry, 103 pts(32%) had at least 1 hospital admission for HF,and 53 patients(17%) had > = 3 admissions,whereas after 1 year 17 patients(5%) were admitted once and 30 patients(9.1%) had >=3 readmissions (p < .0001);15 patients died. At baseline visit, 57% patients were in NYHA class I,30% in NYHA class II,12,5% in NYHA class III and 0,5% patients were in NYHA class IV. At 12 month of follow up,12 % worsened NYHA class pts,40% unchanged pts and 48% ameliorated pts(p < .001 for improving trend). At entry and after 1 year respectively 44 and 46% of patients received ACE-inhibitors, 32,4 and 60 % Angio II-inhibitors, 51 and 73% B-blockers, 65 and 71% diuretics, 11 and 8% digoxin, 24 and 22% calcium channel blockers, 15 and 21% nitrates and 17 and 21% aldosterone receptor antagonists. Conclusions: The specific care and educational/support intervention program was effective in reducing readmission and ameliorating NYHA class of HF and HBP patients without any significant variation in pharmacological therapy.


This work's intention is to show through the analysis of the political configuration on racial relations in Brazil in the late 1990's and beggining of this century that a new and specific field of public policies has been launched: the promotion of racial equality. In order to achieve this goal, I examine the creation and the development of several affirmative action programs started under Fernando Henrique Cardoso's governorship (1995-2002), which were spread through many Ministries, such as Justice, Agricultural Development, Education, Foreign Affairs, Work and also in the higher Brazilian court, Supremo Tribunal Federal, so that we have the chance to understand the meaning and the effects of those policies and also of the official speech that helped to increase the debate on racial relations in our country.


The unity of instrumentality and humanity was a characteristic definition to the Chinese language discipline, which was neither "literature" nor "word". It meant "written language",and was the combination of "oral" and "written" language.It was a social phenomenon both materially and spiritually. Its function was to express, communicate and transfer. Language, thinking and thought is not only unified, but also different. Chinese teaching should be based on humanity and seeking the unity of content and form of teaching.


Currently, potential analysis of local chicken becomes very important in such an economic crisis situation. Such potentials should consider at least three aspects, i.e.: socially acceptable, economically reachable, and technologically applicable. By contrast, local chickens have characteristics of low productivity due to its less development of management and selection system. In fact, indigenous knowledge on selection system is practically existed amongst village community but received little attention and favor by scientists, such as Catur Rangga (four domain features of food chicken) which has not been elaborated yet. The objectives of the research were (a) to analyze the productivity of selected local chicken; (b) to analyze the farmer indigenous knowledge an local chicken; (c) to analyze the relationship of the productivity of selected local chicken and farmer indigenous knowlege. The method used in this study case was Participation Rural Appraisal (PRA) technique, which was the participation of group members was implemented through the Focal Discussion Group (FGD). Data to verify indigenous knowledge system development were based on variables, i.e.: (1) Indigenous knowledge system, included the parameters of bone, flume, crown, legs, eyes, anus bone, foot fingers, head, and back; (2) Productivity, which was the egg productivity per month. Rank Spearman test was used as analytical tool, whilst the data interpretation was used Guilford. The result of the research showed that (a) the productivity of selected local chicken was 20.45 eggs/month; (b) farmer indigenous knowledge system indicated its relevance to modern scientific knowledge; (c) there was a high relationship between productivity and farmer indigenous knowledge system.


Abstract This is the first in a pair of articles in which we draw on C.S. Peirce's semiotics (theory of signs) to develop a new approach to the Christian concept of Incarnation. In this article (Part 1) we use Peirce's taxonomy of signs to explore what it means to understand the life of Jesus as the embodiment of the quality of the life of God within the fabric of the created order. In Part 2, we explore some ways in which this semiotic approach to the Incarnation offers constructive opportunities in theological anthropology and suggests some empirically testable hypotheses about human evolution.


Charge transfer state (CT) plays an important role in exciton diffusion, dissociation, and charge recombination mechanisms. Enhancing the utilization and suppressing the recombination process of CT excitons is a promising way to improve the performance of organic solar cells (OSCs). Here, an effective method is presented via introducing a delayed fluorescence (DF) emitter 3,4‐bis(4‐(diphenylamino)phenyl)acenaphtho[1,2‐b]pyrazine‐8,9‐dicarbonitrile (APDC‐TPDA) in OSCs. The long‐lifetime singlet excitons on APDC‐TPDA can transfer to polymer donors to prolong exciton lifetime, which ensures sufficient time for diffusion and dissociation. Concurrently, the high triplet energy level (T1) of the DF material can also prevent the reverse energy transfer from CT to T1. APDC‐TPDA‐containing ternary OSCs shows a high PCE of 16.96% with a reduced recombination energy loss of 0.46 eV. It is noteworthy that the ternary OSC also exhibits superior storage stability. After 55 days of storage, the PCE of the ternary OSC still retains about 96% of its primitive state. Furthermore, this ternary strategy is efficient and universally applicable to OSCs, and positive results can be obtained in different systems with different DF emitters. These results indicate that the ternary strategy provides a new design idea to realize high performance OSCs.


Thank you unquestionably much for downloading democracy corruption and the politics of spirits in contemporary indonesia the modern anthropology of southeast asia.Maybe you have knowledge that, people have look numerous times for their favorite books gone this democracy corruption and the politics of spirits in contemporary indonesia the modern anthropology of southeast asia, but end taking place in harmful downloads.


Cylinder internal combustion engine fuel supply method and apparatus, comprising: a control amount of the throttle valve of the intake air throttle member, is connected to the member, comprising a plurality of shunt charge to each cylinder is formed extending at its outlet, each cylinder intake passage branching air supply and the fuel injection valve installation having more than one orifice may be injected into several directions on this intake passage. As the injection timing of the fuel injection valve, it is located at the middle of the plurality of cylinders or cylinder bank intake stroke of the cylinder, while a plurality of each cylinder is injected from the orifice, having a fuel injection valve can be uniformly to a plurality of cylinders ejection stabilization effect dispensing.


Pain becomes a socially constructed experience when it is expressed to others. Several psychosocial factors can affect how one interprets another's pain. One of the elements that has been little studied is the position of an individual in the social hierarchy, a concept that is nevertheless central to social interactions. The main goal of this study was therefore to see how the hierarchical position of individuals influenced their evaluation of the pain of others. To do so, the perception of the hierarchical position of each participant was experimentally manipulated. Then, they were asked to judge the intensity of pain expressed in video clips of facial expressions of pain. Despite the effectiveness of the manipulation, analyses showed no effect of hierarchical position on reported pain intensity scores. This study is the first behavioral study to examine the relationship between hierarchical position and the assessment of others' pain.


The application of bacterial endotoxin test (BET) using TAL reagent on radiopharmaceutical kits is very important to conduct. The radiopharmaceutical kits that will be tested are macro aggregated albumin (MAA), tetrofosmin and ethambutol kits. Endotoxin testing stage was TAL 0.25 EU/mL verification test, inhibition/enhancement test, and endotoxin test for sample. Pyrogen testing using rabbits was also performed as a comparison test. The results of the TAL reagent verification test were all samples showed values corresponding to the standards of 2λ = (+), 1λ = (+), 1/2λ = (-), 1/4λ = (-), and negative water control (NWC) = (-). Furthermore, inhibition/enhancement tests for MAA, tetrofosmin, and ethambutol products show non-inhibiting or gel-inducing results, which are in accordance with acceptability standards, so that the samples can be tested using TAL reagents. The pH measurement results in each sample were MAA of 6.0, tetrofosmin of 7.0, and ethambutol of 8.0. The results of MAA, tetrofosmin, and ethambutol product testing were a sample = (-), positive product control (PPC) = (+), positive water control (PWC) = (+), and NWC = (-). In addition, the results of pyrogen testing also showed negative for MAA, tetrofosmin, and ethambutol.


ABSTRACT Solar energy rollout has environmental and socio-economic impacts vital for just low-carbon energy transitions. The modular characteristics of solar photovoltaics enable multi-scalar deployment. How do environmental and socio-economic impacts vary across scales? This understudied relationship impacts the socio-spatiality of solar rollout, who benefits, and how this is enabled. Our study in Portugal during 2017–2020 examines how solar energy went from subsidies to record-setting competitiveness. Most new solar capacity was large scale, with barriers for community energy that weakened in 2020. We draw on interviews with 80 experts and a small-scale questionnaire survey with solar energy cooperative members. Findings show large-scale solar rollout primarily yielded environmental benefits, whereas small scale yielded socio-economic benefits. We argue that near-future joined-up solar energy policies can facilitate synergistic interactions across three United Nations Sustainable Development Goals by integrating environmental and socio-economic impacts. This main contribution can inform Portuguese and wider energy policies for sectoral development toward sustainability.


Purpose
The purpose of this paper is to review the latest management developments across the globe and pinpoint practical implications from cutting-edge research and case studies.

Design/methodology/approach
This briefing is prepared by an independent writer who adds their own impartial comments and places the articles in context.

Findings
Resilient organizations are better positioned to manage major crises and restore the status quo or achieve levels of performance that exceed pre-disruption standards. Successful navigation of a crisis situation can be achieved if key resilience drivers are identified and the firm is equipped with sufficient social and human capital and has an open culture.

Originality/value
The briefing saves busy executives and researchers hours of reading time by selecting only the very best, most pertinent information and presenting it in a condensed and easy-to-digest format.


AbstractIn Sweden, air transport is considered as an alternative for the shipment of uranium hexafluoride (UF6). The radiological consequences of an aeroplane accident involving UF6, transport have been estimated and are presented as the dose from acute exposure and the dose from long-term exposure caused by ground contamination. Chemical effects of a UF6 release are also discussed. A number of limiting scenarios have been defined, resulting in different mechanical and thermal impacts on the transport packages. The expected accident environment and the physical and chemical behaviour of the material have been used to derive a source term for the release to the air. A Gaussian dispersion model has been used to calculate the expected air concentration downwind from the accident site. The radiation dose from short-term exposure was found to be higher than the long-term exposure from uranium deposited on the ground.


In this paper, we propose a novel benchmark called the StarCraft Multi-Agent Exploration Challenges(SMAC-Exp), where agents learn to perform multi-stage tasks and to use environmental factors without precise reward functions. The previous challenges (SMAC) recognized as a standard benchmark of Multi-Agent Reinforcement Learning are mainly concerned with ensuring that all agents cooperatively eliminate approaching adversaries only through fine manipulation with obvious reward functions. SMAC-Exp, on the other hand, is interested in the exploration capability of MARL algorithms to efficiently learn implicit multi-stage tasks and environmental factors as well as micro-control. This study covers both offensive and defensive scenarios. In the offensive scenarios, agents must learn to first find opponents and then eliminate them. The defensive scenarios require agents to use topographic features. For example, agents need to position themselves behind protective structures to make it harder for enemies to attack. We investigate a total of twelve MARL algorithms under both sequential and parallel episode settings of SMAC-Exp and observe that recent approaches perform well in similar settings to the previous challenge, but we discover that current multi-agent approaches place relatively less emphasis on exploration perspectives. To a limited extent, we observe that an enhanced exploration method has a positive effect on SMAC-Exp, however, there is still a gap that state-of-the-art algorithms cannot resolve the most challenging scenarios of SMAC-Exp. Consequently, we propose a new axis for future research into Multi-Agent Reinforcement Learning studies.


In order to overcome the time-consuming computational drawback of using computational fluid dynamics (CFD) for the numerical simulation of aircraft wake vortex evolution under different crosswind velocities, this paper proposes a wake vortex prediction model based on a convolutional neural network (CNN) algorithm. The study focuses on the B737-800 aircraft, and employs CFD numerical simulations to obtain the evolutionary characteristics of wake vortex parameters under crosswind velocities ranging from 0 to 7 m/s. The wake vortex velocity and Q-criterion vorticity values are collected and partitioned into mutually exclusive training and testing datasets. A CNN model is constructed, and the training dataset is used to tune hyperparameters to minimize loss and achieve accurate predictions. After saving the trained model, the desired crosswind velocity value is input to obtain the predicted wake vortex velocity and Q-criterion vorticity values. The results indicate that the convolutional neural network model exhibits an average absolute percentage error of 1.5%, which is 2.3% lower than that of the fully connected neural network model. This suggests that convolutional neural networks can enhance the accuracy of wake vortex predictions, as demonstrated in this study. Compared to traditional CFD methods, the proposed model reduces the computation time by approximately 40 times, effectively improving computational efficiency and offering valuable insight for studies involving numerous numerical simulations, such as analyzing the safety separation between aircraft wake vortices during paired approach procedures.


DESCRIPTION Android is a free, open source, Java-based mobile platform developed by Google. Android in Action, Third Edition prepares the reader to embrace the Android mobile platform in easy-to-understand language and builds on this foundation with reusable Java code examples. It's ideal for corporate developers and hobbyists who have an interest, or a mandate, to deliver mobile software. Android in Action, Third Edition familiarizes the reader with the Android approach to mobile applications. Following the release of Android 3.0, the Honeycomb version for tablets, this edition has been updated to cover hot topics such as the new 3.0 UI framework, Bluetooth, integration, web development strategies, AppWidget framework, sensor management, and the Android Native Development Kit. RETAIL POINTS Updated to cover the Android 3.0 SDK, designed for tablets. Shows how to create real world 3.0 apps for developers. Crisp, clear, and fun to read.


Wireless Sensor Network (WSN) is a network with large number of tiny sensor devices which are of low cost, and minimum consumption of power called as sensor nodes. These type of nodes have great sensing technology which are specifically designed for applications such as military, smart homes and other security related areas. Due its wireless nature, network can be deployed anywhere in the environment, which becomes more vulnerable for attackers to destroy the network. Most importantly, WSN should be protected from malicious activities to take place and thus security becomes a major issue. However, such security can be provided by applying mechanisms for both intrusion detection and prevention. In our study, pattern matching is one of the mechanism that can be used for security of WSN. We also discuss some of the preventive measures that can be considered for protecting the sensor network.


This essay, a revision of remarks originally delivered as part of the Chapman Dialogues series at Chapman University School of Law, is a response to the remarks of Professor William Eskridge of Yale Law School making the case for the recognition of a constitutional right to same-sex marriage. The essay argues that the judicial establishment of a right in the face of deeply entrenched social norms, prior to the time at which the political groundwork necessary for the enforcement of the right has been laid, risks a powerful and ultimately counterproductive backlash.


ObjectivesThe shelf life of fresh beef trimmings is typically determined qualitatively rather than quantitatively by industry. Shelf life is a function of color stability, lipid oxidation, odors and flavors, and microbial spoilage. The objectives of this study were to determine the number of storage days at which aerobically stored beef trimmings reach the end of shelf life and to increase understanding of the relationships between the mechanisms of spoilage. Materials and MethodsUSDA select T. brachii (TB) and B. femoris (BF) were sliced to 1.27 cm, placed on plastic trays, covered with O₂ permeable plastic film, and stored at 5°C under fluorescent lighting (150 to 300 lux). On storage d 0, 3, 6, 9, and 12 samples were evaluated for color, pH, volatile compounds, aerobic mesophile (AM), and aerobic psychrotroph (AP) plate counts. L*, a*, b* color was measured, hue angle (HA) and saturation index (SI) were calculated and samples were scanned for spectral reflectance (400 nm to 700 nm) to determine percentage of myoglobin. A modified nitric oxide reducing ability (MNORA) method was used on d 0 through 9 to determine potential metmyoglobin reducing ability (MRA) given the addition of reduced nicotinamide adenine dinucleotide (NADH). To quantify volatile compounds associated with rancidity and other off odors/flavors, headspace volatiles were collected using a solid phase micro extraction field sampler and quantified using GC–MS. Data were analyzed with ANOVA (ɑ = 0.05) using muscle and storage day as main effects. Tukey least squares means were calculated for significant main effects and interactions and mean separations were determined by the PDIFF function. Simple Pearson correlation coefficients were calculated between measured attributes. ResultsThe L* values decreased from d 0 (40.74) to d 12 (30.63). The SI values decreased (p < 0.05) from d 0 (27.09) to d 12 (11.92). Percent metmyoglobin (MMb) was lowest on d 0 (19.98%) and highest on d 6 (38.75%) and were only similar (p < 0.05) on d 9 and 12. The a* values for both muscles decreased (p < 0.05) from d 0 (BF 20.84; TB 20.75) to d 12 (BF 8.83; TB 6.93). The pH increased (p < 0.05) for both TB and BF from d 0 (BF 5.51; TB 5.63) to d 12 (BF 6.62; TB 6.79) pH was higher (p < 0.05) for TB on all days. Relative MRA declined over storage time though values on d 0 (56.99%) and 3 (64.57%) were higher (p < 0.05) than on d 6 (40.12%) and 9 (29.07%). Of the headspace volatiles, only total alcohols increased significantly (p < 0.05) from 57,791 on d 0 to 265,152 on d 12. The AM and AP both increased (p < 0.05) from d 0 to d 12, reaching 7 log₁₀ CFU/cm² by d 9. Significant (p < 0.001) correlations were present between pH and color attributes (pH:L*, r = -0.83; pH:a*, r = -0.74; pH:SI, r = -0.86). a* values correlated (p < 0.001) with both AM (r = -0.84) and AP (r = -0.71). Total alcohols highly correlated with both AM (p < 0.01, r = 0.52) and AP (p < 0.001, r = 0.58). ConclusionThe end of shelf life was determined to be d 6 for color attributes and d 9 for microbial growth and off odors/flavors. Pearson correlations showed strong evidence of interrelationships between color, pH, and microbial growth on aerobically stored beef trimmings. This study was the initial phase of a project that will focus on strategies to extend shelf life of fresh beef trimmings by improving color after d 6 and preventing further microbial growth and off odor/flavor development at d 9.


This paper presents a set-partitioning formulation and a novel decomposition heuristic (D-H) solution algorithm to solve large-scale instances of the urban crowdsourced shared-trip package delivery problem. The D-H begins by dividing the packages between shared personal vehicles (SPVs) and dedicated vehicles (DVs). For package-assignment to SPVs, this paper enumerates the set of routes each SPV can traverse and constructs a package-SPV route assignment problem. For package-assignment to DVs and routing, the paper first obtains DV routes by solving a conventional vehicle routing problem and then seeks potential solution improvements by switching packages from SPVs to DVs. The switching process is cost driven. The D-H significantly outperforms a commercial solver in terms of computational efficiency, while obtaining near-optimal solutions for small problem instances. This paper presents a city-scale case study to analyze the important service design factors that impact the efficiency of crowdsourced shared-trip delivery. The paper further analyzes the impact of three important service design factors on system performance, namely (i) the number of participating SPVs, (ii) the maximum detour willingness of SPVs, and (iii) the depot locations. The results and findings provide meaningful insights for industry practice, while the algorithms illustrate promise for large real-world systems.


Functionalized (Z,E)-1-halo-1,3-dienol esters are synthesized in a highly stereoselective manner via CrCl2-mediated rearrangement of allylic trihalomethylcarbinol esters induced by microwave irradiation.


Argonne's Model for Universal Solvent Extraction (AMUSE) simulates multistage counter-current solvent extraction processes for species of interest to spent nuclear fuel reprocessing; it is a model of a liquid–liquid extraction unit operation. This work extends the model from its original steady-state implementation to include a time-dependent description of all species of interest. Major components of this extension include a differential mass transfer term, a description of interstage flow rates, and a reaction network for plutonium reduction. The mass transfer term has been formulated using a lumped efficiency term in place of a mass transfer coefficient; the plutonium reduction reactions have been formulated to ensure consistency at all operating conditions. Several nonequilibrium behaviors during simulations have been identified, which allows for improved safety monitoring during process start up and disturbance response.


An elastomeric bushing is a device used in automotive suspension systems to cushion the loads transmitted from the wheel to the frame of the vehicle. A bushing is essentially an elastomeric hollow cylinder which is bonded to a solid metal shaft at its inner surface and a metal sleeve at its outer surface. The shaft is connected to the suspension and the sleeve is connected to the frame. The elastomeric cylinder provides the cushion when it deforms due to relative motion between the shaft and the sleeve. The relation between the force or moment applied to the shaft or sleeve and the relative displacements or rotations is nonlinear and exhibits features of viscoelasticity. A force(moment)-displacement(rotation) relation for elastomeric bushings is important for multibody dynamics numerical simulations. A boundary value problem for the bushing response leads to a relation which requires extensive computation time to implement and is hence unsuitable. In a separate study, a force(moment)-displacement(rotation) relation for single mode response has been proposed which can be used in multi-body dynamics simulations. The relation is expressed in terms of a force (moment) relaxation function for the bushing, and a method for its determination by experiments on bushings has been presented. The applicability of this relation for torsional mode bushing response is evaluated in the present work. A boundary value problem is formulated for torsional mode bushing response. Numerical solutions of the boundary value problem represent the exact bushing response and act as numerically generated experimental data. The proposed moment-rotation relation is constructed using this data. Numerical solutions of the boundary value problem also allow for comparison between the exact moment-rotation behavior and that predicted by the proposed model. It is shown that the method for determining the bushing relaxation function and the predictions of the proposed moment-rotation relation are in very good agreement with the exact results.


Many sports tournaments contain a round-robin group stage where the teams are assigned to groups subject to some constraints. Since finding an allocation of the teams that satisfies the established criteria is non-trivial, UEFA has adopted a procedure based on a random draw assisted by the computer to indicate the group(s) available for the drawn team. It is shown how this mechanism is connected to generating permutations, and a straightforward modification is proposed to increase the excitement of the draw. The consequences of draw restrictions are investigated through the case study of the European Qualifiers to the 2022 FIFA World Cup. We assess the probability of an obscure situation that threatens the transparency of the draw and quantify the departure of the UEFA mechanism from an evenly distributed random draw among all feasible allocations.


Castritis of bile backstreaming is a common and frequently encountered disease in internal medicine of stomach intestine,and it is the main pathogenesis to gastritis of bile backstreaming that under many cases bile backstreams,and stomach mucous membrane is destroyed by bile salt,From 2005,we have take clinical observation on 176 cases given Conbined Treatment of TCM and western medicine, and the recovery rate reached 54.5%,improvement rate 40.9%,total effective rate 95.3%,And it is welcomed by many patients because its better curative effect and lower cost.


4BSTRACT minimizing grid orientation effects, Coats and Ramesh (4) applied the prooedure proposed by Yanoeikand McCracken h the pact few years there has been increased interest in to simulating thermal recovery processes and obtained a modeling miscible and thermal recovery processes by the similar reduction of grid orientation effects. .!seof reservoir simulation models, The prediction of sharp maturation or temperature fronts resulting from these The application of nine-point difference equf,tlons to processes has shown that these simulators can in many homogeneoussystems with uniformgrid spacing & straightcasesbe very senaitlve to grid orientation. One method for forward. However the extension to non-uniformgrids with minimizing the effect of grid sensitivity is to describe the difference equations with a nine-point rather than the heterogeneous permeability is not as simple as it might first appear. This paper presents a consistent method for standard five-point finite difference approximations, [nherent in the use of the nine-point approximations is the calculating the nine~oint transmissibilities that may be


Introduction 1. The founder saints and the crusades 2. Pope Gregory IX and the early friars 3. Papal crusade propaganda and the friars 4. The organisation of the preaching of the cross in the provinces of the mendicant orders 5. Friars, crusade sermons, and preaching aids 6. The friars and the financing of the crusades 7. The friars and the redemption of crusade vows Conclusion.


We report a comparative study using knowledge space theory (KST) to assess the impact of a hands-on laboratory exercise that used molecular model kits to emphasize the connections between a plane of symmetry, chirality, and isomerism in an introductory organic chemistry course. The experimental design compared three groups of students-two that carried out the laboratory exercise (treatment groups) and one that did not (control group). Our assessments revealed that all three groups made significant improvements in their understanding of chirality and isomerism, but that the two treatment groups showed more improvements than the control group. The KST analysis showed that the acquisition of the skills for finding a plane of symmetry in a molecule came late in the students' critical learning pathways, which indicated that this was difficult for many students. Students were unfamiliar with this type of reasoning, and our studies revealed that the laboratory exercise was useful in teaching the method to introductory organic chemistry students.


Introduction: Lack of knowledge in primiparous women about the process of vaginal delivery usually causes anxiety. This anxiety can have negative impacts on fetus, mother and childbirth process. Therefore, supporting the mother can reduce her anxiety and help her to cope better with labor. We aimed to determine the effect of listening to the Quran on reducing anxiety and serum cortisol levels in primiparous women during the first stage of labor. Methods: This clinical trial study was conducted in 2013 on 60 pregnant women who had vaginal delivery in Zainab hospital of Shiraz, Iran. Parturients were randomly allocated into interventional and control groups. In the interventional group, parturients listened to the Quran for 45 minutes using headphone during the active phase of labor. However, in the control group no audio was played through the headphone. Women's anxiety was measured with Spielberger questionnaire before and after using the headphone and cortisol levels were also evaluated. Data were analyzed using SPSS software (version 21) and chi-square, paired t-test, Fisher and Kruskal-Wallis tests. P value less than 0.05 was considered significant. Results: Hearing the Quran was effective in reducing anxiety in the interventional group and this effect was statistically significant between two groups (p<0.001) The serum cortisol levels was 101.47±48.00 µg/l in the intervention group and 226.53±105.77 µg/l in the control group after hearing the Quran and the difference was statistically significant (p<0.001). In the intervention group, anxiety was reduced more effectively in parturients with high familiarity with the Quran (p<0.05). Conclusion: Listening to the Quran during the labor, especially in women who are much more familiar with the Quran has positive effects in reducing anxiety. This method is a valuable technique with high quality effects on normal vaginal delivery process that may reduce cesarean delivery without indication.


The modern physiography of central Turkey is dominated by the 1-km-high Central Anatolian Plateau and the Central Tauride mountains that form the southern plateau margin. These correspond to a Cretaceous–Eocene backarc extensional province and forearc fold-thrust belt, respectively. The extent to which the morphology of the Miocene plateau was inherited from the physiography of the Cretaceous–Eocene subduction zone that assembled the Anatolian crust has not been tested but is important if we are to isolate the signal of Miocene and younger subduction dynamics in the formation of the modern plateau margin. There is no known stratigraphic record of the post-Eocene pre-Miocene evolution of the Taurides. We therefore collected rock samples across the Taurides and used zircon (U-Th)/He (ZHe), apatite (U-Th)/He (AHe), and apatite fission-track (AFT) low-temperature thermochronometers to constrain cooling; we interpret these thermochronometers to signal erosional exhumation. We use inverse thermal modeling to aid interpretation of our results and find that: (1) thermochronometers across the Taurides were reset as a result of heating by the emplacement of the Antalya and Bozkır nappes; (2) AFT and ZHe Eocene cooling ages are related to structurally driven uplift and erosional exhumation on major thrust culminations; (3) dispersed AHe ages record low rates of Oligocene–early Miocene cooling and hence low rates of erosional exhumation; and (4) fast rates of cooling were determined for samples along the margin of the Köprüçay Basin. We interpret that early Miocene cooling is a signal of active erosion of the western Central Taurides at a time of marine sedimentation in the Mut Basin on the southern Central Taurides, and these differing histories may reflect evolution above the Antalya and Cyprus slabs. Our thermochronological data, the enigmatic development of the Antalya Basin, and thrusting within the basin may be explained as the surface expression of stepwise delamination of the Antalya slab from the Tauride hinterland to its current position below the Gulf of Antalya since early Miocene time over a distance of ∼150 km.


The preservation of nature requires the identification, description and evaluation of the ecosystems at different observation levels, for the establishment of appropriate conservation policies for various targets, in complex contexts, guided by different philosophical and ecological approaches. A methodological proposal was formulated in this study to tackle the analysis of Pumalin Park's ecosystems through its characterization, classification and zonification, besides an exploratory study of the philosophical and scientific context of the conservation policy of the protected area. To achieve this, a geographically homogeneous area was delimited, a biophysical and ecological description was realized and the ecology of the area was represented in a systemic model. All this, as the basis for a hierarchical ecosystems classification at three ecological relation scales. A main macroscale ecosystem was identified, following the general pattern defined by climate and orography; nine mesoscale units, joined in valleys, mountains, plains and beaches; and, forty three microscale ecosystems defined mainly by plant associations in the area. After the zonification, it was concluded that the largest area is dominated by north patagonian batolith mountains, and alluvial or fluvio-glacial valleys. At a lower level, a plant associations mosaic can be found, dominated by Nothofagus nitida, Nothofagus betuloides and Fitzroya cupressoides. Through an evaluation of the provision of ecological processes, the highest values were obtained at wooded ecosystems. In the ecosystems sensitivity analysis, high values were assigned to the entire area, while the highest were found at Huequi's peninsula. Very high naturalness ecosystems were identified at almost the entire extension of the wooded mountains; high naturalness and richness at Huequi's peninsula; and high naturalness and fragility at the highest mountain areas In the analysis of the conservation policy context, the information was organized in nine ethical or philosophical arguments and five scientific or ecological imperatives for wilderness protection; besides six targets of wild protected areas; which were organized into a hierarchical order, through a consultation with experts chosen by their relevance for the case of study.


The kinetic profile for free radical photopolymerization of a low viscous acrylate resin was found to exhibit an unusual behaviour under atmospheric conditions: two successive waves of polymerization were observed and characterized by RT-FTIR and confocal Raman microscopy. The first wave is merely attributed to the conventional photoinitiation process with a good depth curing but a surface layer which is strongly inhibited by molecular oxygen. During this inhibition process, hydroperoxides are generated at a relatively high concentration. After full consumption of the photoinitiator, these hydroperoxides are further responsible for the second polymerization wave. Depth profiling experiments and determination of the variation of hydroperoxide concentration with time confirm this assumption.


A numerical model is developed for the simulation of moving interfaces in viscous incompressible flows. The model is based on the finite element method with a pseudo-concentration technique to track the front. Since a Eulerian approach is chosen, the interface is advected by the flow through a fixed mesh. Therefore, material discontinuity across the interface cannot be described accurately. To remedy this problem, the model has been supplemented with a local mesh adaptation technique. This latter consists in updating the mesh at each time step to the interface position, such that element boundaries lie along the front. It has been implemented for unstructured triangular finite element meshes. The outcome of this technique is that it allows an accurate treatment of material discontinuity across the interface and, if necessary, a modelling of interface phenomena such as surface tension by using specific boundary elements. For illustration, two examples are computed and presented : the broken dam problem and the Rayleigh-Taylor instability


The paper addresses the problem of modeling and planning of the future. It presents the problems of developing a model of the future due to the ideologies and strategies of some ruling political parties. The authors deal with the means of expression of the model of the future as one of the most important elements of the lingvo-mental image of political world in the context of program documents of the parties. The authors examine a program of a party as a part of political communication system and characterize the model of the future. On the basis of comparative study the authors determine common and specific features of the model of the future expression. A comparative study of the model of the future expression on the material of ruling parties of Russia and a variety of foreign countries (the United States, Great Britain, France, and Italy) is extremely relevant in the current period of global economic crisis. Such a research provides the basis for the optimal model of the future determination that can become a universal one for the electorate of different countries. Thus, the authors reveal the most advanced model of the future representation. © 2014 The Authors. Published by Elsevier Ltd. Selection and peer-review under responsibility of Tomsk Polytechnic University


SETTING
In low-incidence regions, tuberculosis (TB) often affects vulnerable populations. Guidelines recommend active case finding (ACF) in homeless populations, but there is no consensus on a preferred screening method.

OBJECTIVE
We performed a systematic review and meta-analysis to evaluate the use of chest X-ray (CXR) screening in ACF for TB in homeless populations.

DESIGN
Articles were identified through EMBASE, Medline and the Cochrane Library. Studies using symptom screens, CXRs, sputum sweeps, tuberculin skin tests and/or interferon-gamma release assays to detect active TB in homeless populations were sought. Data were extracted using a standardised method by two reviewers and validated with an objective tool.

RESULTS
Sixteen studies addressing CXR screening of homeless populations for active TB in low-incidence regions were analysed. The pooled prevalence of active TB in the 16 study cohorts was 931 per 100 000 population screened (95%CI 565-1534) and 782/100 000 CXR performed (95%CI 566-1079). Six of seven longitudinal screening programs reported a reduction in regional TB incidence after implementation of the CXR-based ACF programme.

CONCLUSION
Our data suggest that CXR screening is a good tool for ACF in homeless populations in low-incidence regions.


A metastable analytic continuation of the Ising model free energy is conjectured to follow from certain analyticity properties of the eigenvalues of the transfer matrix. The resulting description of metastability is applicable to any system whose phase transition is associated with eigenvalue degeneracy. Motivation for the conjectures concerning the Ising model is provided by the study of eigenvalue continuation in several simpler systems.


The invention provides a power implementation method and system for a multi-core chip. The method comprises the following steps that the number of threads distributed by each core is obtained; the execution time of each thread is obtained; power is distributed for each core according to the number of the threads and the execution time of the threads. The power implementation method and system for the multi-core chip have the advantage of achieving internal power distribution.


In this paper, an efficient real-time iris center detection and tracking system has been proposed based on the vector field of image gradients (VFOID). The system uses video frames from cost-effective lowresolution USB cameras and natural lighting condition instead of high resolution sensors and infrared illumination. The proposed algorithm includes multi-stage approaches. Firstly, the AdaBoost-based cascaded classifiers are used to detect and track face region and its location in the image. Then, the facial feature points in the face region are extracted to locate the rough area of the eyes. Finally, the VFOID are used to accurately detect and track the iris center within the estimated eye areas. The experimental result shows a high accuracy on existing database and in a real-world environment.


U.S. medical autopsy rates have dropped from approximately 45% in the 1960s to less than 8% in recent years, and interest is growing in use of


Collaborative filtering is one of the most effective and adequate technique used in recommendation. The fundamental aim of the recommendation is to provide prediction of the different items in which a user would be interested in based on their preferences. Recommendation systems based on collaborative filtering techniques are able to provide approximately accurate prediction when there is enough data. User based collaborative filtering taechniques have been very powerful and success in the past to recommend the items based on user's preferences. But, there are also some certain challenges such as scalability and sparsity of data which increases as the number of users and items increases. In a large website, it is difficult to find the interested information in a certain time. But the recommendation system filter out information and items that are best suitable for us. Although there are different recommendation approaches, yet collaborative filtering technique is very popular because of the effectiveness. In this work, movie recommender system has been described, which basically uses item-based technique of collaborative filtering to provide the recommendations of items, which is dynamic and will learn from the positive feedback.


On the Semantic Web, vocabularies and ontologies play a fundamental role to express the terminology and rules of certain domains. New technologies like SHACL provide the possibility to express data schemata specific to certain data sets, applications, and domains. However, the domain modeling process is collaborative and when using RDF, it requires technical knowledge. In this paper, we present a tool to support a two-step-process to model a terminology and a schema with a combined graphical RDF Schema editor and visual SHACL editor. This tool allows domain experts to create a terminology and schema without the need for a deep understanding of RDF Schema or SHACL. Demo URL: https://ontopad.aksw.org/


In the paper the models of socially-oriented economies are characterized. It is revealed the concept of social market economy and social functions of the state. The composition of social policy is determined. It is characterized such models of socially-oriented economies as continental, Anglo-Saxon, Scandinavian, Southern European, neoliberal and paternalistic. It is proved that the most successful version of the welfare state is a Scandinavian welfare model. It is conducted the comparison of the social economy models. It is defined the criteria by which models of the social market economy differ. It is proved that under current economic conditions a new paradigm of social policy that combines three forces: state, market and civil society. It is highlighted the general trends of functioning of the European social-oriented economies.


Winston Leonard Spencer-Churchill was the greatest British statesman of the past century, and perhaps of any century. Yet in the popular imagination he has become little more than a stereotype. Lord Moran's book is remarkable in that it is an intimate portrayal of the doctor-patient relationship, except that the patient happens to be Churchill himself, and the picture that emerges is anything but stereotypical.

In May 1940, when Moran was plain Sir Charles Wilson, the author took on the guardianship of Churchill's health. From the ensuing 25 years a book emerged that is a biography, an autobiography, and …


Abstract Problem, research strategy, and findings: Scenario-based planning offers the promise of enhancing local coastal management given uncertainties from shoreline dynamics and climate change. Deploying it can require substantial capacity, however, or can obscure the key policy choices a community faces. We set out to develop and test a simple, decision-centered approach to scenario-based planning as a way to improve local management of coastal shorelands through master plans, focusing on coastal hazard mitigation. We also looked for ways to use basic spatial analysis techniques and off-the-shelf data sources that could be manipulated to generate meaningful and reasonably accurate analyses. We find the simplified and decision-centered methods we have developed can provide useful information for local decision makers. We also find the quality of the master plans adopted by two partner localities that used our scenario-based planning methods substantially exceeds the quality of comparison plans with regard to coastal management. Takeaway for practice: Using simplified, decision-centered, scenario-based planning methods can facilitate enhanced hazard mitigation analysis and policy adoption in local master plans. Those methods necessarily will and should be tailored to the unique political and physical conditions of the community, as demonstrated by the leadership provided in the localities studied here.


cities in different historical periods but focuses on the 19th century, arguing that non-Muslims exploited the Ottoman reforms to move out from, or reshape, their own urban social environment. The author's overview of the dynamics of the internal and external relationships of non-Muslims also shows that this characterization was valid mainly for the upper and educated classes, while little is known about the lower classes. Krämer correctly argues that in spite of the cosmopolitanism of an urban space, the "vertical" element of religious and ethnic identification was never supplanted by the "horizontal" idea of social class. The last essay by Sami Zubaida analyzes the urban sociopolitical movements from 1750 to 1950. In this complex but well-argued essay, Zubaida aims to identify a pattern of urban politics present in Ottoman cities and its development through the 19th century until the mid-20th century. Zubaida challenges the idea that senior –ulama» were the leaders of the urban population. Using the example of Cairo, he argues that it was not the distinguished scholars but the lower clergy that played a prominent role in popular movements. Then, he introduces the idea that the majority of urban poor were not politically organized or under the control of parties or organizations but were largely responsive to Islamic appeals frequently used to mobilize the masses. In sum, this diverse collection of essays on the urban social history of the Middle East is not groundbreaking, but it provides a greatly anticipated assessment of the status of this particular field. A perusal of the book shows that such a project has been in the planning stages for years (as Sluglett points out in the preface), which is a testimony to the necessity of thoroughly assessing this area of research. This also means that despite the clear effort of the contributors, some of the essays are not up to date. Nevertheless, the text is still a very welcome contribution and a must read for those involved in urban and social history of the Middle East.


It all started with a night of bowling in Austin, Texas, when fifth-grade student Amit had an evening of fun with his grand-parents. When Amit returned to his home in Lubbock, TX, and tried to replicate his newfound recreation, his night of bowling fun ended after 10 minutes in an asthma attack. His second attempt at Lubbock bowling also brought a return of the asthma terror. He said, "My mother didn't let me go back again. This became sort of serious because I wanted to have some fun." After Amit identified the problem as the secondhand smoke in the bowling alley, he started seeking a solution to this problem. To redress this situation, fourth- and fifth- grade students Abby, Amit, Ben, David, Lori, Rachel, and Wade started a campaign called STIR: Stop Tobacco in Restaurants. The goal was to end smoking in public places, including restaurants, bowling alleys, sports bars, and pool halls. For 2 years they motivated their peers and coordinated an information campaign to urge kids and adults to find out about the dangers of secondhand smoke, and they eventually succeeded in passing a city ordinance banning smoking in public places.


Abstract This article examines the roles of religion and sprituality in the etiology and treatment of eating disorders. After briefly reviewing the relevant research, we discuss the most common and significant religious and spiritual issues that we have observed with patients with eating disorders, including negative images or perceptions of God, feelings of spiritual unworthiness and shame, and fear of abandonment by God. We briefly describe process considerations for sing spiritual interventions and conclude by describing seven spiritual interventions that we have found especily useful in treating eating disorderpatients, including spiritual teachings, spiritual bibliotherapy, and pmyer.


In this paper we use Renyi representation of order statistics to provide a tight lower bound on the outage probability and a tight upper bound on the average signal-to-noise ratio of orthogonal space-time coded systems with antenna selection. Using these bounds we propose a chi-square approximation to the outage probability. We show through simulations that the bounds and also the chi-square approximation are quite tight for a variety of antenna configurations. The method presented here is quite general and not restricted to the Rayleigh distribution.


We apply mid-infrared near-field microscopy with broad-band spectroscopic operation to problems in biomineralization. Inspecting tooth material we find vibrational resonances of phosphate nanocrystals distinctly shifted from bulk phosphates. This is enabled by the extraordinary spectral narrowing promoted by the near-field interaction over far-field FTIR.


The effects of organic impurities(trioctyl phosphate and methyl ester),inorganic impurity ammonium and Pb2+ on the electrowinning process of zinc in ZnSO4-H2SO4 system were investigated.The methods of removing the effects on electrowinning process of zinc by organic impurity trioctyl phosphate and inorganic impurity Pb2+ were studied.The experimental results showed that methyl ester had little influence on electrowinning process of zinc while trioctyl phosphate had big influence on it.Normal electrolytic zinc can be obtained by electrowinning after adsorption treatment with active carbon.Ammonium had almost no influence on electrowinning process of zinc while Pb2+ influenced the quality of cathode zinc greatly.The addition of suitable additive SrCO3 can effectively reduce the lead content in cathode zinc after the lead plate activated,and 0# zinc can be obtained under certain conditions.


Review and assess the features of administrative law for the violation of road safety. Particular attention is paid to the application of administrative penalties in the form of oplatnogo seizure of the vehicle and public works.


About the stages of creation of wood carving, which is a type of applied art. This article gives an idea of where the art of wood carving has been used in our country since ancient times, the history of their development.


W.J. Schafer Associates Inc. has conducted an assessment of the capabilities of small satellites to fly material experiments in low earth orbit in order to measure the environmentally induced material degradation. A potential experiment was chosen for the assessment which requires spacecraft pointing in the forward velocity vector (ram direction), a minimum of power, and low data storage. A satellite designed to be launched from a Space Shuttle Get Away Special (GAS) is nominally able to meet these requirements if a simple drag stabilization system is used, if all the available surface area is used for solar panels and if the experiment's power requirement is minimized through the use of passive thermal control.


Introduction: Revascularization of patients with heavily calcified coronary arter- ies can be a challenge for interventional cardiologists. Calcified lesions often cre-ate problems during PCI and require the use of more aggressive techniques, typi- cally associated with a greater risk of complications. The procedural success rate in these patients can be improved by using rotational atherectomy (RA), which is a technique to modify the atherosclerotic plaque and facilitate stent delivery and implantation. Purpose: The aim of this study was to compare clinical characteristics and out- comes during hospitalization and at 12-month follow-up between patients who underwent RA as a bailout procedure secondary to failed conventional angioplasty or as an elective procedure. Methods: Thisisaretrospectiveanalysisof156consecutivepatientshospitalized at a high-volume PCI center between 2009 and 2016 who underwent RA. In 113 patients (72.4%) designated as group 1, RA was carried out after unsuccessful traditional angioplasty (inability to cross the lesion with a balloon, balloon under- expansion). In 43 patients (27.6%) designated as group 2, RA was performed on an elective basis. Before and after the procedure, quantitative coronary angiogra- phy of the treated lesions was performed by two independent interventional car-diologists. Procedural success was defined as successful stent implantation with stenosis of less than 20% diameter and TIMI-3 flow. The primary endpoint was in-hospital and 12-month all-cause mortality. Secondary endpoints included my- ocardial infarction (MI), the need for repeat target vessel revascularization (TVR) or revascularization of the treated lesion (TLR), stroke, and all major adverse car- diovascular and cerebrovascular events (MACCE) which consisted of death, MI, TVR, TLR, and stroke. Results: Patients in the two groups did not differ with regard to sex, age, or car- diovascular risk factors. Patients in group 1 more often had a history of previous coronary interventions (74.3% vs 51.1%; p=0.05). Group 2 was dominated by pa- tients with multivessel disease (33.6% vs 62.8%; p < 0.001). Left main was more often treated in group 2 (2,7% vs 25,6%; p < 0.001). The success rates in the two groups were similar: 91.2% for group 1 and 93.0% in group 2 (p=0.70). The rate of in-hospital complications did not significantly differ between groups. There was one in-hospital death in group 2. During the 12-month follow-up, MI occurred in 7.1% of patients in group 1 and 4.7% of patients in group 2 (p=0.58), TLR oc- curred in 5.3% and 2.3%, respectively (p=0.42), and TVR occurred in 7.1% and 4.7%, respectively (p=0.58) There was no difference in the 12-month survival rate (91.2% in group 1 vs 86.1%, p=0.35) and MACCE (15.0% vs 16.3%; p=0,85). Conclusions: RA treatment is associated with high efficacy and a relatively low risk of complications, with no significant differences in outcomes between patients treated with primary and secondary RA procedures.


7-Al_2O_3 catalyst was modified by P、B and Si promoters to obtain catalysts with different acidities.NH_3-TPD was used to characterize effects of the promoters(P、B and Si) and the content of B on the surface acidity of the resultant catalysts.The skeletal isomerization catalytic performances of the P、B and Si modified catalysts were evaluated with 1-pentene as a model compound.The results indicated P,B and Si modification changes the surface acidity and skeletal isomerization reactivity of the catalysts.P promoter reduces the acidity of 7-Al_3O_3,B and Si promoters increase the acidity ofγ-Al_O_3.B and Si promoters are able to increase the skeletal isomerization activity and the isopentene yield.


Drug discovery depends on scientists finding compounds with molecular fingerprints similar to the target drug, or pharmacophore. A new way of improving the accuracy of molecular fingerprint folding is presented. The goal is to alleviate the growing challenge of excessively long fingerprints. This improved method generates a new shorter fingerprint that is more accurate than the basic folded fingerprint. Information gathered during preprocessing is used to determine an optimal attribute order. The most commonly used blocks of bits can then be organized and used to generate a new improved fingerprint for more optimal folding. The authors then applied the widely used Tanimoto similarity search algorithm to benchmark the results. The authors showed an improvement in the final results using this method to generate an improved fingerprint compared to other traditional folding methods.