W e analysis the chemical reaction and radiation effects on free convective flow of a viscous incompressible electrically conducting fluid through a porous medium bounded by a inclined surface with constant heat and mass flux under the influence of uniform magnetic field. The non- dimensional governing equations are solved by the perturbation method. The expressions  are  found for velocity ,temperature and concentration field and studied for different parameters such as thermal Grashof number, mass Grashof number, Schmidt number, permeability parameter, Prandtl number, magnetic number, chemical reaction parameterand radiation parameter. More importantly, the results of numerical solution of present study agree well with the earlier results study in a particular case (i.e. without radiation).


Aqueous two-phase system composed of PEG4000/NaH2PO4 was evaluated in the extraction of Geotrichum sp.SYBC WU-3 lipase.Factors of molecular weight,concentration of PEG,concentration of NaH2PO4,and pH on the lipase were investigated.The optimized conditions by orthogonal test design was as follows: PEG concentration of 30%,NaH2PO4 concentration of 20%,pH 6.At these conditions,the activity of Geotrichum sp.SYBC WU-3 lipase was 22 times of the crude product.The lipase was a low-adapted alkaline lipase,the optimum temperature was 15 ℃,the optimum pH was 9.5,and the molecular weight was 3.58×104.


The aetiology of rheumatoid arthritis (RA) is complex. In particular, the vast majority of disease-associated variants implicated by genome-wide association studies are non-coding, leaving genetic mechanisms of adaptive immune dysregulation unresolved. The contribution to this process of epigenetic factors, including the addition of methyl groups to DNA, also remains uncertain. To address these issues and prioritise causal genes for downstream study, genome-wide data incorporating DNA methylation and gene expression measurements from lymphocyte subsets in an early arthritis inception cohort, were available.

 Whole genome methylation and transcription data from isolated CD4+ T cells and B cells of > 100 well-characterised inflammatory arthritis patients, all of whom were naïve to immunomodulatory treatments and of Northern European ancestry, were obtained (Illumina HumanHT-12 v4 Expression BeadChip and Infinium MethylationEPIC BeadChip arrays, respectively). Genotyping was undertaken using the Illumina Human CoreExome-24 version 1-0 array. After independent pre-processing, normalisation and quality control of paired CD4+ and B lymphocyte data, methylation quantitative trait loci (meQTLs) were first modelled using the MatrixEQTL package in each cell type. Next, at RA risk-associated cis-CpGs, correlations between site-specific methylation and the expression of genes within ±500Kb identified quantitative trait methylations (eQTMs). To infer directionality of SNP-CpG-transcript associations a causal inference test (CIT) was applied. Multiple testing was accounted for, and in vitro assays were used to validate meQTLs at loci of interest and confirm regulatory mechanisms. Further analysis integrated GWAS data from other immune mediated diseases (IMDs) and additional publically available resources.

 We found strong evidence that disease-associated DNA variants regulate cis-CpG methylation of DNA in CD4+ T and/or B cells at 37% RA loci. In general we observed these variants to preferentially modify methylation at sites mapping to lymphocyte enhancers and regions flanking transcription start sites, and at positions bound by the NFκB transcription factor. Using paired, cell-specific transcriptomic data and a statistical approach to infer causality, we then identified examples where site-specific DNA methylation in turn mediates gene expression, including ORMDL3/GSDMB, IL6ST/ANKRD55, FCRL3 and JAZF1 in CD4+ lymphocytes. Leveraging GWAS data we noted that a number of genes regulated in this way highlight mechanisms common to RA, multiple sclerosis and asthma, distinguishing these IMDs from osteoarthritis which is considered a primarily degenerative disease. To validate our findings, cis-meQTL effects at sentinel loci were replicated by pyrosequencing in an independent cohort of genotyped early arthritis patients, and methylation-mediated regulation of FCRL3 expression downstream of the regulatory SNP was confirmed experimentally using a luciferase reporter assay in Jurkat T-cells.

 Our observations highlight important mechanisms of genetic risk in RA and the wider context of autoimmunity. They confirm the utility of DNA methylation profiling as a tool for causal gene prioritisation and, potentially, therapeutic targeting in complex IMD.

 A.D. Clark None. N. Nair None. A.E. Anderson None. N. Thalayasingam None. N. Naamane None. A.J. Skelton None. J. Diboll None. A. Barton None. S. Eyre None. J.D. Isaacs None. L.N. Reynard None. A.G. Pratt Grants/research support; I am a recipient of an unrestricted, investigator initiated research grant from Pfizer, paid to Newcastle University.


Currently, a special type of computer system's that has its roots in the foundations of Artificial Intelligence disciplines, takes shape and strength. They are the "Agents Software Systems". Thus, the goal of this paper is to present this kind of software. As a result, shows that the these new tools to build software, allows better scalability of computerized software solutions, at the same time that can assists processes where the mining of information happens in heterogeneous environments.


Performance is Dot a twentieth-century history that can be elaborated, but a development from two specific moments of art and dance in the early '60s and '10S. Rather than rush to provide a theoretical base or historical context for a phenomenon that is no one thing, this paper examines one particular peIfonnance by a dancer/choreographer turned performance artist.


A 62-year-old female with a productive sputum was pointed out of a mass of 2.5 cm in diameter in left S4 with lymphadenopathy of station 10, 4, and 3 on computed tomographic scan, which were heterogeneously enhanced by radiocontrast agent. She was diagnosed with pulmonary adenocarcinoma and clinical stage IIIA (T1N2M0, N2-multistation). First-line induction therapy of cisplatin plus paclitaxel had been performed but failed to respond to the chemotherapy. Second-line induction therapy of gefitinib for 6 months had showed the shrinkage of the tumor and resulted in a down-stage (T1N0M0, IA). Positron emission topography revealed no abnormal accumulations of the primary tumor and the mediastinal lymph nodes. As salvage surgery, left upper lobectomy was performed and the pathology revealed negative findings of metastasis in lymph nodal station 4, 5, 6, 7, and 11 but in a positive in station 10. The viable cells in the tumor had been residual (Ef.2) and diagnosed with stage IIA (pT1N1M0). Detection test of epidermal growth factor receptor gene mutation showed a negative result. The patient obtained 5-year's long-term survival without metastasis and recurrence. The combination therapy of gefitinib-induction therapy followed by surgery for advanced lung cancer with N2-multistation would have an advantage of good outcome for such patient in the limited gefitinib-responded population as tailor-made therapies.


In this paper, the meaning of real estate enterprises informatization is discussed according to the current situation of evaluating real estate enterprises informatization in China. It puts forward the index system of real estate enterprise informatization, and presents a way to evaluate the level of real estate enterprises using the system parameter fusion principle.


2009 News Literacyeracy Conference Photos, set 12 (Thurs index Profile Shots) 1024 x 6831/160 sec / 1.250 mm ISO 200 Canon EOS-1Ds Mark III


This paper introduces a simulation analysis of the temperature field of a single stage traveling wave launcher.The heat source of the projectile and the coils,the equivalent thermal conductivity of the coil winding the radiating coefficient of the projectile and the radiating coefficient of the coils are caculated.And the temperature field distribution graph of the coil and the projectile are also given.


Particle method is a well-known approach that has been used for a long time in charged particle beams or plasma physics modeling. In recent years, particle based methods have become widespread tools for approximating solutions of ordinary/partial differential equations in a variety of fields. In these methods, a solution of a given equation is represented by a finite set of particles, located in points xi and carrying masses ωi. Equations of evolution in time are then written to describe the dynamics of the location of the particles and their weights. The aim of this lecture is to show that this method can provide a useful tool of simulation in biology and chemistry. In the first part, we recall the principles and the basic properties of the particle method. Numerical and algorithm considerations are also exposed. In the second part, examples of reformulation of problems from other fields, like chemistry and biology, which allow the use of particle based modeling, are presented.


With the particle swarm optimal (PSO) algorithm, an adaptive fuzzy logic controller (AFC) based on interval fuzzy membership functions is proposed for vehicle non-linear active suspension systems. The interval membership functions (IMFs) are utilized in the AFC design to deal with not only non-linearity and uncertainty caused from irregular road inputs and immeasurable disturbance, but also the potential uncertainty of expert's knowledge and experience. The adaptive strategy is designed to self-tune the active force between the lower bounds and upper bounds of interval fuzzy outputs. A case study based on a quarter active suspension model has demonstrated that the proposed adaptive fuzzy controller significantly outperforms conventional fuzzy controllers of an active suspension and a passive suspension.


The peritoneum is a rare location for endometriosis, with a reported incidence of parietal endometriosis of approximately 0.03 to 0.4%. It most often occurs in the aftermath of a caesarean section and is associated with pelvic endometriosis in only 5 to 15% of cases. Rare cases of malignant transformation have been described, mainly in the form of clear-cell tumours.


The configuration dependent self-association mode of the two anomers of O-Ac,N -Fmoc-D-Glucosamine, a foldamer building block, leading to gel and/or single crystal formation is described. The β-anomer of the sugar amino acid ( 2 ) forms a gel from various solvents (confirmed by SEM, rheology measurements, NMR and ECD spectroscopy), while the α-anomer ( 1 ) forms none of those tested. Transition from solution state to gel is coupled to a concurrent shift of the Fmoc-groups: from a freely rotating (almost symmetrical) to a specific, asymmetric orientation. While the crystal structure of the α-anomer is built as an evenly packed 3D-system, the β-anomer forms a looser superstructure of well-packed 2D-layers. Modeling indicates that in the lowest energy, but scarcely sampled conformer of the β-anomer, the Fmoc-group bends above the sugar moiety, stabilized by intramolecular CH↔π interaction between the aromatic rings. We conclude that possessing an extended and promiscuous interaction surface and a conformationally heterogeneous solution state are among the basic requirements of gel formation for a candidate molecule.


We aim to create a constant DC output source from a variable input AC source wherein the perturbations on the output side due to addition of load on the system does create an impact on the output profile of the system. Through the use of PID controllers and Fuzzy Controllers, we seek to lock the output at a desired value. The results from the usage of both the controllers are checked and compared and the best design is then tested with various output configurations and for stabillity in varying loading conditions


An increasingly important problem in physics concerns scale invariance symmetry in diverse complex systems, often characterized by heteroscedastic dynamics. We investigate the nature of the relationship between the heteroscedastic and fractal aspects of the dynamics of complex systems, by analyzing the sensitivity to heteroscedasticity of the scaling properties of weakly nonstationary time series. By using multifractal detrended fluctuation analysis, we study the singularity spectra of currency exchange rate fluctuations, after partially or completely eliminating n-point correlations via data shuffling techniques. We conclude that heteroscedasticity can significantly increase multifractality and interpret these findings in the context of self-organizing and adaptive complex systems.


Abstract A title compound has been synthesized and characterized. The complex crystallizes in the orthorhombic space group Cmcm with a = 7.004(2) A, b = 12.748(2) A, c = 13.665(2) A, V = 1220.1(3) A3 and Z = 4. The complex consists of two-dimensional square arrays of nickel(II) ions bridged by pzdc2 and pyz ligands. Each nickel ion has a slightly distorted octahedral coordination with N4O2 chromopher. The magnetic susceptibility data over a range of 2–300 K were fitted by using an Heisenberg antiferromagnet with a mean field approximation. The obtained J and zJ' values are −1.70 cm−1 and −0.70 cm−1, respectively.


We extend the work of Goncalves & Meddahi (2009) who suggest using the iid and wild bootstrap for realized volatility instead of the asymptotic approach in order to estimate integrated volatility. We propose the block bootstrap and GARCH residual bootstrap approaches motivated by the persistence of the intraday term structure of returns. Using Monte Carlo simulations we show that the block bootstrap is more accurate for a low intraday frequency, more robust and valid. Another result is that the GARCH bootstrap outperforms others when the data imply strong persistence in conditional heteroskedasticity. It also demonstrates good inference on simulated data along the baseline model with a high frequency. However, the GARCH bootstrap is more computationally costly and less robust than the others.


The maize is the third biggest grain crops,important feed crops,and the important material of the modern food and the chemical industry.The maize embryogenic calli are often used as the direct acceptor of the foreign gene in the process of the transgene.Using the maize immature embryo for tissue culture is the main way to gain the embryogenic callus efficiently.In this study,the immature embryos of inbred line maize that have good resistances and are suitable for local planting were selected to conduct the experiment of callus inducement of explant.A culture system for embryogenic callus was established to provide acceptor materials for maize genetic transformation.


The world wide experience of communication and cooperation of diasporas and origin countries shows various ways and forms how diasporas can contribute towards sustainable development of origin country. Lithuania also has relatively huge diaspora and faces increasing emigration every year. However, it still neglects the potential of it's diaspora involvement in contributing to well-being of the country. In order to reveal the potential of Lithuanian diaspora the qualitative research was conducted. It used expert interview method with 12 leaders of foreign Lithuanian communities and organizations. The research revealed that Lithuanian diaspora is willing and could contribute significantly to the country's sustainable development in various areas: scientific, business, cultural and social ones. In order to facilitate this cooperation, Lithuanian government should decrease barriers for cooperation and implement measures that would take into account the diversity of diaspora groups interests and possibilities, provide relevant information about means of engagement and support already existing and new diaspora networks and their initiatives.


Superplastic deformation of the new generation of aerospace aluminium-lithium alloys has generated considerable interest in the aerospace industry not only with the potential savings in component weight and manufacturing costs but also for development of novel designs. Even though many papers have addressed the superplastic deformation characteristics of these alloys it is essential for their exploitation to determine and to understand the effect of the forming process on their mechanical properties. This paper presents results on the effect of superplastic strain and post form heat treatment on the tensile and fatigue performance of the Al-Li-Cu-Mg-Zr (8090) alloy with a low and high copper content of 1-1.2 wt% and 1.56 wt% respectively. Both alloys were superplastically formed biaxially under an imposed back pressure to prevent intergranular cavitation. For the low copper containing alloys the tensile properties decreased with superplastic strain and were independent of quench rate. In contrast the tensile properties of the high copper containing alloy were quench rate sensitive. The as-formed and aged strength were initially lower than those determined for the low copper alloy although both the 0.2 % proof stress and the tensile strength increased with superplastic strain. Incorporation of a solution heat treatment with a cold water quench prior to ageing resulted in a strength increase of 50 MPa over that determined for the low copper alloy and the tensile properties decreased with superplastic strain. The reduction in strength with superplastic strain is related to changes in the ageing kinetics resulting from dynamic recrystallisation and grain growth, which was similar for both alloys. The higher strength of the high copper alloy following re-solution heat treatment is due to enhanced homogeneous S phase precipitation. The S phase precipitation was reduced in the as-formed and aged material due to precipitation of a copper rich phase during the slower air cool, resulting in the lower strength. The fatigue performance, under sinusoidal loading and stress ratio (R) = 0.1, was similar for both alloys and the endurance limit was slightly reduced with increased superplastic strain. The results are compared to those for the aluminium-lithium alloy 8091, which has a higher copper content and with those for the superplastic aluminium alloys Supral 220 and 7475E. The implication of the results for manufacturing practice is also discussed.


This guidance note underscores the potential of education technology (EdTech) solutions in transforming learning, teaching, and training systems during and after the coronavirus disease (COVID-19) pandemic. Since the COVID-19 outbreak, governments have been coping with and responding to the challenges posed by the closure of education institutions while guidelines from international agencies seek to address the disruptions and responses. Drawing from and reinforcing the key principles of these courses of action, the guidance note also provides suggestions and pointers that stakeholders in developing countries can consider for a long-term road map to improve quality, relevance, and inclusion in education.


Copper-zinc mining pollution effects on riparian and aquatic vascular plants were studied in the Northwest Miramichi River system of northern New Brunswick. After a period of 8 years, the riparian vascular flora of the river system's gravel shores has been completely eliminated or seriously reduced. The most sensitive plants are the submersed aquatic species, followed by riparian dicotyledons. Monocotyledons are less sensitive than dicotyledons and Equisetum arvense the least sensitive species. A rough index of pollution severity was devised based on the absence of species or species groups which would normally be present under unpolluted conditions.


The system and technical advantages of mulched drip irrigation were introduced in paper, it had advantages for water conservation, increase land use efficiency, reduce the manual labour, increase economic benefits, reduce dis-eases, pest-insects and weeds, and environmental protection et al. it summarized the decline in rice acreage and ecologi-cal deterioration because of water shortage, extending of mulched drip irrigation in shihezi can abate the shortage of a-gricultural water, protect the ecological environment, maintain and expand rice farms, it is conducive to build sustainable and healthy way on high quality rice in Ningxia and have better application prospects.


1. Consider complex analytic mappings f of a noncompact Riemann surface R into a compact or noncompact Riemann surface S of finite or infinite genus. If the integrated Euler characteristic E(Q) of an exhausting subregion Q c R does not grow more rapidly than the characteristic function C(Q) off, then the defect sum is finite [2]. In the general case there can be infinitely many Picard points and nothing is known about the set of defect points. We shall show that the defect points under every f are so scarce that


In this paper we report the synthesis and characterization of a series of electrochromic polyamides (alternating copolymers). The synthesis proceeds via the condensation polymerization between amine‐capped oligoaniline and acyl chlorides such as isophthaloyl dichloride, terephthaloyl chloride, azelaoyl chloride, and dodecanedioyl dichloride. Both the orthogonal tert‐butoxycarbonyl (BOC) group on the oligoaniline segment and the non‐conjugated aromatic or aliphatic segment on the polymer backbone play a vital role in the formation of the final polyamides with good solubility in common organic solvents. We cast thin polyamide films from their chloroform solutions and studied their electrochemical behavior and spectroscopic properties. In contrast to the polyaniline, the copolymers bearing oligoaniline segments show four distinct oxidation states, which were fully characterized using IR and UV‐vis spectroscopy. The copolymer thin films also exhibit electrochromic behavior when a linear potential sweep is applied. Compared with the polyaniline, the polyamides adhere much more strongly to the indium tin oxide (ITO) coated glass and show no signs of delamination after hundreds of redox cycles in a hydrochloric acid solution. We believe that these factors make these novel polyamides very attractive as electrochromic materials.


Plants of three winter wheat varieties (Favoritka, Smuglianka, Mironovskaya 808) were grown in a pot experiment on two levels of mineral nutrition — N 160 P 160 K 160 and N 32 P 32 K 32 mg/kg of soil. In the phase of flowering and at full ripeness dry weight of the main shoot organs, their nitrogen content, elements of grain productivity and grain nitrogen content were determined. Ratios of nitrogen remobilization during grain filling for the whole shoot and its individual parts have been calculated. It was shown that in new winter wheat varieties Favoritka and Smuglianka efficiency of nitrogen remobilization from vegetative parts to the grain was higher than in the old variety Mironovskaya 808 plants. Under low level of mineral nutrition remobilization ratios were less, but new varieties retain an advantage in this index. At the high level of mineral nutrition varieties Favoritka and Smuglianka used stem nitrogen better than Mironovskaya 808.


Summary
Successful resuscitation of a trauma-induced, suspected tension pneumomediastinum in a dog is presented. The cause was a caudal cervical penetration wound which acted as a one-way valve allowing air to enter, but not exit, the cranial mediastium. Early in the course of hospitalization, respiratory and cardiovascular collapse occurred; an emergent parasternotomy allowed decompression of the mediastinum, and the cradiovascular system immediately responded. The dog made a complete recovery following surgical exploration and removal of contaminated mediastinal tissue. Nine days of intensive care included 24-hour monitoring, oxygen therapy, intravenous crystalloids and colloids, continuous pleural suctioning, nutritional support, antibiotics, and pain control.


Objective To discuss the evaluation value of conduction velocity distribution (CVD) test with computer-assisted collision technique in diabetic peripheral neuropathy patients and its relationship with TCM syndromes. Methods Totally 148 patients with diabetes Ⅱ were selected to receive CVD test and were compared with NCV test. Furthermore they were classified into TCM syndromes, given score in 5 grades and given the related lab tests. Results The rate of CVD abnormality was 86.1%, which was remarkably higher than MCV or SCV test synchronously (P0.01). The course and 2hPBG were the independent risk factors for CVD abnormality. There was a negative correlation between blood sugar and motor nerve conduction velocities. The frequency of Yin-deficiency syndrome and blood-stasis syndrome was more than 50%. The proportion of Yang-deficiency arose in the longer-course group (P0.05). Besides, the proportion of Yang-deficiency syndrome and blood-stasis syndrome were significantly higher in the group aged60 than in the group aged≤60(P0.01). The risk of CVD abnormality increased as the scores of Yang-deficiency, blood-stasis and phlegm-damp upgraded. Conclusion CVD test with computer-assisted collision technique is more sensitive than NCV test and can serve as an early and effective index for evaluation of DPN. The course and blood glucose are the independent risk factors for CVD abnormality. Yang-deficiency, blood-stasis and phlegm-damp syndromes have certain effects on the parameters of CVD.


In high-speed ball bearings, external load has a great effect on cage stability and sliding ratio, especially for the bearings at work in the starting process. For this paper, a dynamic model of high-speed ball bearings was developed, and cage stability both under steady conditions and during the starting process was analyzed based on the model. The effect of external load on cage stability was evaluated taking into consideration the two different working conditions. The results show that cage stability is worse in the beginning of the bearing starting process. According to the investigation of cage stability on different external loads, it can be concluded that the axial load greatly influences cage dynamic performance in the bearing starting process. In addition, while ball bearings worked under steady conditions, axial load and radial load both have a great influence on cage dynamic performance. The effects of axial load on cage dynamic performance during the bearing starting process are opposite from the effects under steady conditions.


A 66-year-old white man was hospitalized with an asymptomatic bladder diverticulum detected on ultrasound. History was uneventful and there were no symptoms of fever, pain or obstipation. Voiding was reported to be normal with a frequency of 4 to 6 times during the day and 0 to 1 time at night. Physical examination of the abdomen showed no abnormalities. On digital rectal examination the prostate was small and not suspicious. Ultrasound revealed left hydronephrosis and a 21 ml. volume of the prostate was measured on transrectal ultrasound. Complete blood count, serum creatinine, electrolytes, prostate specific antigen, urine sediment and urine culture were normal. Peak urinary flow rate was 4 ml. per second with a post-void residual between 400 and 2,000 ml. The preoperative International Prostate Symptom Score was 20. Cystogram revealed a large bladder diverticulum with a volume of 8.5 1. (fig. 1). An excretory urogram demonstrated left hydronephrosis and computerized tomography (CT) of the abdomen confirmed that the diverticulum was clearly separated from the bladder wall (fig. 2). Urodynamic studies demonstrated infravesical obstruction. Cystoscopy showed a small but obstructive prostate with an otherwise normal urethra. The bladder mucosa was normal and inspection of the diverticulum demonstrated neither tumor nor stone formation. A suprapubic catheter was inserted to achieve adequate tonus of the bladder wall. At transurethral resection of the prostate 12 weeks later a total of 15 gm. was resected. Postoperatively peak urinary flow rate was 36 ml. per second with a post-void residual of 80 ml. Left hydronephrosis was not present. The symptom score was 13 compared to 20 before therapy. Due to these parameters no open diverticulectomy was performed and at 3-month followup there were no symptoms or complaints. DISCUSSION


AIM
Many currently available pharmacogenomic assays and algorithms interrogate a set of 'tag' polymorphisms for inferring haplotypes. We wanted to test the accuracy of such haplotype inferences across different populations.

MATERIALS & METHODS
We simulated haplotype inferences made by existing pharmacogenomic assays for seven important pharmacogenes based on full genome data of 2504 persons in the 1000 Genomes dataset.

RESULTS
A sizable fraction of samples did not match any of the haplotypes in the star allele nomenclature systems. We found no clear population bias in the accuracy of results of simulated assays.

CONCLUSION
Haplotype nomenclatures and inference algorithms need to be improved to adequately capture pharmacogenomic diversity in human populations.


It has often been observed that "Where power is, women are not." Noting women's virtual absence from the realm of conventional politics, Jane Jaquette urged scholars in 1980 to look beyond elections in studying female political participation in Latin America. Arguing for an "expanded notion of the political," she called for research on female participation within different social classes, especially their role in "informal networks, … clientele linkages, … strike activities, urban land seizures and barrio politics". This article employs a community study method to investigate women's grass-roots participation in politics and labor mobilization following World War II in the region of greater São Paulo known as ABC (named after the municipios of Santo André, São Bernardo do Campo, and São Caetano).


Summary form only given. Atomic Force Microscopy has been described as a powerful technique for studying insulating, hard, surface. Since then, it is also considered as an appropriate technique for investigating at a submicromic scale elastic and viscoelastic properties of soft material as polymer films. Here we show that macroscopic models, namely Hertz, Johnson Kendall Roberts and Maugis-Barquins ones, can be fruitfully employed. With this continuum approach, we interpret either the roughness observed with the topographical mode or the force curves obtained in A.F.M. for polymer films. Finally this approach should allow to clarify the conditions for which the macroscopic approach fails.


We examined the time‐varying characteristics of cerebral autoregulation and hemodynamics during resting state and hypercapnia by using recursively estimated multivariate (two‐input) models which quantify the dynamic effects of mean arterial blood pressure (ABP) and end‐tidal CO2 tension (PETCO2) on middle cerebral artery blood flow velocity (CBFV). Experimental measurements of spontaneous variations of these signals were obtained from thirteen healthy subjects under normal, free‐breathing conditions. Beat‐to‐beat values of ABP and CBFV, as well as breath‐to‐breath values of PETCO2 were also obtained in 8 female subjects during baseline and sustained euoxic hypercapnia. The multiple‐input, single‐output linear models used to describe the relationship between ABP, PETCO2 and CBFV were based on the Laguerre expansion technique. In order to account for the different dynamics associated with each input, the model parameters were updated using a recursive least squares scheme with constant and adaptive multiple forgetting factors. The results reveal the presence of nonstationarities that are more pronounced in the very low frequency range. By comparing one‐input (MABP) and two‐input (MABP and PETCO2) models, our results point out that the incorporation of PETCO2 as an additional input yields less time‐varying estimates of dynamic pressure autoregulation obtained from single‐input (MABP‐CBFV) models, suggesting the important role of PETCO2 and the possible shortcomings of assessing dynamic autoregulation using such models.


Acoustic data are presented from a 40 percent scale model of the 4-bladed BO-105 helicopter main rotor, measured in the large European aeroacoustic wind tunnel, the DNW. Rotor blade-vortex interaction (BVI) noise data in the low speed flight range were acquired using a traversing in-flow microphone array. The experimental apparatus, testing procedures, calibration results, and experimental objectives are fully described. A large representative set of averaged acoustic signals is presented.


The expression of Tumor protein D52 (TPD52) family members is deregulated in many types of cancer. When overexpressed, it is suggested that they increase cell proliferation and migration/invasion as well as avoid apoptosis. Deregulation in the expression of the TPDs is therefore linked to poor prognosis. Little characterisation has been carried out to date, but it is known that the TPDs are found in association with components of the membrane trafficking pathway. The aim of this work is to uncover how the least studied member of the family, TPD54, affects cellular processes involved in carcinogenesis, such as cell migration and invasion. By using the knocksideways method, we have been able to map the cellular localisation of TPD54 and have identified association partners. These associations have been confirmed by immunoprecipitation and mass spectrometry analysis. Amongst these was the small GTPase Rab14. We have also found that TPD54 is involved in the trafficking of receptors containing a dileucine motif in their cytosolic tail, but not a tyrosine-based or NPXY motif. With the mapping of the localisation of TPD54, we hypothesise that TPD54 is on the recycling route following the Golgi apparatus, and in association with Rab14, regulates the trafficking of receptors containing a dileucine motif. Integrins are receptors controlling cell migration. They can be trafficked through the Golgi apparatus before being recycled back to the plasma membrane. This recycling route is not well characterised. We therefore hypothesise that TPD54 regulates this route with Rab14, and that this is the reason why TPD54 is important for cell migration, and that a defect in its function can cause cancer.


Objective:To develop a communication interface software for automated hematology analyzer,to transfer the data from the analyzer automatically.Method:Based on Microsoft.Net technology,with programming of serial communication,host computer was connected to the hematology analyzer by right settings of communication parameters,and the data of the analyzer were captured,analyzed,converted and saved to database by network.Results:With this software,data were transferred automatically.It replaced manual recording,saved manpower and resources costs,improved data accuracy and ensure the qualities of services.Conclusion:The application of communication interface software solved the difficult situation of automatic data acquisition.It helps to push forward the informational process of laboratory.It raises the efficiency and improves qualities of services.It is worth of spreading.


Polymerization of 1-aryl-2-trimethylsilylacetylene (aryl = thienyl, furyl, and pyridyl) was carried out by transition metal catalysts. The polymer yield was generally low due to the steric hindrance. R4Sn (R = Me, n-Bu, Ph) exhibits some cocatalytic activities with respect to polymer yield and molecular weight. On the other hand, the polymerization was decelerated when organoaluminum compounds were used as cocatalysts. The polymer yield increased in the following order: phenyl > thienyl > furyl > pyridyl, according to the aryl substituents. The NMR (1H- and 13C-), IR, and UV-visible spectra indicated that the resulting polymers have a linear conjugated polyene structure each containing the aromatic substituent and trimethylsilyl group. From 1H-NMR integration, it was found that the resulting polymers are partially desilylated depending on the substituents of monomer and the polymerization conditions. The solubility behavior, stability and fluoride-ion induced desilylation reaction of the polymers were also studied.


The energy transition and climate neutrality are a short time scenario as climate concerns are rising fast. Small islands are natural microgrids in which the energy transition is subjected to economic and regulatory constraints and highly challenged by technical issues. As a first step, the Mediterranean island of Favignana has been considered in this study, to assess how electric mobility could impact the power system. According to the plans from the local decision makers, the island is moving towards a full public electric mobility in the near term, also due to the participation in the BloRin project. For this reason, a feasibility study about the technical and environmental impact of electric mobility is highly needed. What appears is that the network is ready for such a transition even if carried out in massive terms, while the current electric mix makes the shift to electric mobility more polluting. Therefore, the assessment of the environmental impact, quantified comparing the emissions of the current scenario with those of a future condition with a 20% penetration of EVs on the island, highlights the need of a simultaneous shift to zero emission power production. The simulations are carried out using the NEPLAN software and considering various operating scenarios. In most cases, the substations are charged two times the current power flows, but never going beyond the rated capacity.


The invention discloses a fine-diameter stretching combined spinneret orifice which is composed of a plurality of fine-diameter spinneret orifices arranged on a spinneret plate and distributed in conically radial mode, wherein conical inlets are arranged at inlet ends of the fine-diameter spinneret orifices. The spinneret plate is provided with a conical guide inlet on the inlet sides of the spinneret orifices, and the conical inlets of the fine-diameter spinneret orifices are connected with the guide inlet. Fluid with containing ultra-high molecular weight polyethylene forms fluid monofilaments through the fine-diameter stretching combined spinneret orifice in combined stretching mode, and then high-strength and ultra-high molecular weight polyethylene monofilaments with the diameter to be equal to or larger than 0.07mm and the breaking strength to be equal to or larger than 1.6 GMa are obtained through post-processing procedures.


We read with interest the article by Zhang et al. on clip-assisted endoscopic cyanoacrylate injection for gastric varices with a gastrorenal shunt [1]. The authors concluded that clip-assisted cyanoacrylate injection was convenient to perform, and safe and effective for patients with gastric varices and a gastrorenal shunt. They also stated the efficacy (100%) of this new technique in managing acute gastrointestinal bleeding. We found this new technique interesting and would like to offer some comments. The reported rate of hemostasis in the study was 100%; however, only four patients experienced acute bleeding and, therefore, it is inappropriate to present the result as a percentage. The study only included patients with large gastrorenal shunts. The reason for inclusion of this specific population while excluding other patients with gastric varices is unclear. The eradication was defined on the basis of computed tomography scan only, and a validated objective criteria used for defining this eradication is not provided. We would also like to know the number of patients who showed complete eradication of varices on repeat endoscopy. At endoscopic follow-up, 36 patients required reintervention. Were any baseline characteristic and/or anatomic locations of the gastric varices found to predict the need for reintervention? There were four cases of exacerbation of esophageal varices after therapy. Was the gastrorenal shunt blocked as a result of embolization in these patients? Do the authors have any pathophysiological insights into this phenomenon? Fever and abdominal pain were reported in 33% and 17%, respectively, in a previous series [2], and bacteremia after glue injection has been documented in 15/47 patients with a positive blood culture [3]. It would be useful to know the exact number of patients with these adverse events in the current series.


We present a review of selected data-analysis methods that are applied in studies of ionospheric electrodynamics and magnetosphereionosphere coupling using ground-based and space-based data sets. At present, there is no single measurement device that can measure all ionospheric electrodynamic parameters directly and simultaneously, with good spatial and temporal resolution and coverage. Therefore data-analysis techniques are needed to combine different types of measured data and to obtain unobserved ionospheric parameters from the observed ones, possibly using some additional assumptions in the process. We concentrate on methods that are data driven and applicable to single events (not simulations or statistical models), and which can be used in mesoscale studies, where the analysis area is typically some hundreds or thousands of km across.


Objective: Pathological excessive sweating that can occur in specific parts for else throughout the body is known as hyperhidrosis. Although there are different medical and surgical options, medical treatment applied to many patients provides temporary relief. With advances in surgical techniques, the most commonly used surgical treatment method is endoscopic thoracic sympathectomy (ETS). In this study, we examined the results of ETS operations performed in our clinic considering the current literature. Methods: Between 15.03.2011 and 30.10.2020, 45 single-port ETS operations were performed on 23 patients due to palmar and/or axillary hyperhidrosis. Patients' demographic data, complaints, complications, therapeutic results, and post-treatment satisfaction were evaluated. Results: Thirteen of the 23 patients were male and 10 were female, with average age of 25. Ten patients were operated for palmar hyperhidrosis, two for axillary hyperhidrosis, and 11 for axillary and palmar hyperhidrosis. Forty-five thoracic sympathectomy operations were performed with bilateral single port ETS in the same session in all but one of the 23 patients. Mean operative time was 28 min, and hospitalization time was 1.1 (0-8) days. Two patients exhibited compensatory sweating during follow-up, and one patient showed rebound sweating. At follow-up, 91% of patients (21) were satisfied with their operations. Conclusion: Endoscopically-assisted single-port thoracic sympathectomy appears to be a reliable and practicable technique for treating hyperhidrosis, with effective results, high patient satisfaction, and early discharge time. We believe that the most important advantages of this technique are an early return to normal life, less pain, and a positive return to social life.


Background Patients prescribed opioids often have chronic conditions that increase their risk of adverse cardiovascular outcomes, but little is known about the primary preventive cardiovascular care these patients receive. Methods and Results We analyzed data from the 2014 to 2016 National Ambulatory Medical Care Survey to evaluate physicians' provision of primary preventive cardiovascular care to adults with and without opioid prescriptions. We included all visits made by adults 40 to 79 years old with at least 1 cardiovascular risk factor but no existing atherosclerotic cardiovascular disease. There were ≈32 million visits by adults who were prescribed opioids and ≈167 million visits by adults not prescribed opioids on an annual basis. The prevalence of primary preventive care was modest in patients with versus those without opioid prescriptions, respectively: (1) statins for patients with dyslipidemia (52.1% versus 46.3%); (2) statins for patients with diabetes mellitus (49.1% versus 37.9%); (3) antihypertensive agents for patients with hypertension (76.5% versus 65.8%); (4) diet/exercise counseling (40.5% versus 45.3%); and (5) smoking cessation therapy (25.3% versus 19.3%). In multivariate analyses, opioid use was associated with higher rates of statin therapy in patients with diabetes mellitus (adjusted relative risk [aRR], 1.25; 95% CI, 1.06–1.47; P=0.007) and antihypertensive medication in patients with hypertension (aRR 1.14; 95% CI, 1.06–1.22; P<0.001). Conclusions Overall adherence to guideline‐recommended primary preventive cardiovascular care during ambulatory visits was suboptimal. Findings show that patients prescribed opioids versus those without opioid prescriptions were more likely to receive statin therapy and antihypertensive agents in the setting of diabetes mellitus and hypertension, respectively. Ongoing efforts to bridge these gaps in primary prevention of cardiovascular disease remain a high priority.


Protein kinase B(PKB/Akt)/forkhead transcription factor(FoxO) signal pathway is a vital signal pathway which is widely present in kidney. In recent years, a variety of studies have shown that Akt/FoxO signal pathway affected the pathophysiological changes of diabetic kidney disease through affecting oxidative stress, cell proliferation and apoptosis, extracellular matrix deposition, autophagy and so on, which plays an important role in the development and progression of diabetic kidney disease.

Key words:
Protein kinase B; Forkhead transcription factor; Diabetic kidney disease


Newspaper clipping of a column by Patricia Collins Hughes discussing the Veterans' Administration claims that the WASP had been paid benefits through the Civil Service Administration. The reverse of the clipping contains the newspaper's masthead and the continuation of an article from page 3.


Combine report function of Plant Design System with Script function of Autocad to get instrument information in models of PDS


To provide a background for an interpretation of Peutinger's memorials on the question of monopolies, the author first considers the roll played by the question of monopolies at the diets from 1512 to 1530 and establishes the economic and politicoeconomic interests of the various groups in the diet, especially the contradictory interests of the South-German free imperial cities. This is followed by an examination oft he evolution of Peutinger's economic and politico-economic views, as well as his ettitude toward the taking of interest. He then analyzes the important memorials. The new economic thought, and the new ethical evaluations which appear in the consideration of specific questions are brought together and placed in their genera] setting. This is done above all in the examination of the memorial of 1530, which opposed the "Advice with respect to Monopolies", the report of the committee on monopolies of the Diet of Augsburg. This recommendation embodies the traditional conceptions concerning the economic order, economic attitudes, and ethics associated with it and haa as its intention the complete return to this old order. I t would bind the individual and his economic activities to a permanent order of companies, would impose governmental regulations upon him, and above all provide governmental insurance in the sphere of economic activity in a "Nahrung" ? But the committee report also contains persistent utterances which reflect a kind of economic nationalism and a desire for autarchy. The dynamic new tendences were to be held in check. Thus it demanded governmental price controls also with respect to foreign trade. Therein lies the reason for the suggestion that an effective barrier be placed in the way of further expansion of the economic institutions, the U 5) So Anton Welser d. Ä. 1504, als er Peutinger einspannt fur die Durchsetzung der Aufhebung des burgundisch-niederländischen Silberexport-Verbotes und ihm eine exakte Darlegung der wirtschaftlichen Auswirkungen des Verbotes, naturlich besonders auf die Geschäfte der Welser, liefert. Vgl. 0 . Peutingers Briefwechsel Xr. 25, S. 45ff., bes. S. 48.


The present paper deals with the proteins. to be extracted from human, placenta, which were studied by means of electrophoresis, determination of solubility against ethanol and immunochemical titration.γ-Globulin from this tissue was successfully purified by ethanol fractionation method proposed by Cohn for plasma proteins, and compared immunochemically with γ-globulin prepared from pooled blood plasma.The results obtained are as follows:1) Normal placenta weighed approximately 400g. in wet weight, and its content of water and proteins were 84 and 12.2 per cent respectively. About one-fourth of total protein could be extracted by immersion of placenta slice overnight in water.2) Electrophoretic analysis of the proteins extracted revealed four components having the same mobilities as those of serum albumin, α- β- and γ-globulins respectively. Considering the pattern observed in case of perfused placenta, the component, of the same mobility as γ-globulin was most likely derived from the tissue itself, while the other cpmponents were probably from contaminating blood.3) Some changes in the electrophoretic pattern caused by autolysis were described.4) 20 per cent ethanol precipitated all antibodies tested, and this fraction was further purified using the method 9 proposed by Cohn.5) γ-Globulin thus purified from placenta manifested a little higher antibody titers for several antigens examined than those of γ-globulin preparation from blood plasma.


In an era of massive energy consumption, wind turbines play their own important role as an integral part of the wider ensemble of alternative energy sources. Their seemingly simple function, however, contradicts the complex nature of the phenomena, occurring from the very first contact between the air mass and the rotating blades' mechanism of such a construction. It is exactly this fact that significantly hinders the simulation of the conditions, under which a wind turbine is expected to produce power and also safely withstand any kind of loads exerted on it. The venture of reproducing these conditions in a computational environment constituted the aim of the current thesis, through the generation of a wind field from a series of stochastic procedures, on the one hand, and the simulation of aerodynamic behavior of both the blades and the tower, on the other. The pertinent calculations were accomplished in Matlab environment, through the generation of an algorithm which, by taking into account various, necessary parameters related to the aerodynamic phenomena, produces wind load time histories for the wind turbine's tower. The results were incorporated as loading conditions into a computational model of the tower, which was created in SAP2000 software, and was subsequently analyzed dynamically, non-linearly, so that the resulting displacement and stress time histories could be examined and the selected sections could be checked for adequacy.


UAVs are becoming extremely essential these days for many applications such as HADR missions. During these missions, there can be a loss of GPS signal due to challenging environments and terrains, and this can hinder the missions so there is a need for a system that provides UAVs the capability to do these missions even in GPS-denied environments. In most of such missions, swarms of UAVs are working. Hence, the aim of this research paper is to propose a reliable GPS-denied navigation system for swarms. The major challenge with the swarm navigation is to achieve inter-UAV collision avoidance. So, this paper mainly focuses on prevention of inter UAV collision. Therefore, to accomplish this objective, the integration of estimations by Visual Odometry and UWB module is proposed in this paper.


Feasibility in elimination of the heavy metallic ions Ni and Cu is studied by adsorption on activated carbons which have been obtained by physical activation with stream of marabu. Operating conditions in terms of temperature ( 600 – 800 oC ) and time between 60 to 120 minutes were analyzed on different carbon's properties, with emphasis one those which are indicated of the absorbent power: methylene blue and iodine indexes. The corresponding analysis to define the influence of the independent variables: temperature ad the time on every answer of interest was carried out. It was obtained that the precursor such as the activating agent studied are appropriate for the preparation of activated carbons with a good absorption capacity. In addition, the conditions to prepare the adsorbents belong to those of experiments 8 and 9 whose products are able to remove the most quantity of the studied metallic ions studied in this work. Key word: Adsorption, activated carbons, physical activation, heavy metals


For a space simply supported truss bridge model, a method named element modal strain energy (MSE) was firstly adopted in the field of the optimal sensors placement. By taking nodes MSE, nodes distance matrix reciprocal as weights, and combining with optimal matching in graph theory, how to apply the method for optimal sensors placement was stated. Through analyzing on the random vibration property of the bridge finite element model, the nodes position of larger acceleration response was compared with the optimal placement got from the above method, which could verified the effectiveness of optimal sensors placement.


An AI-centered view on the recent trends in the computer integrated manufacturing (CIM) area is presented. The shift in the CIM-software concepts towards both the object-oriented philosophy and the fast-prototyping methodology was simulated by the AI-theoretical backgrounds. The software life cycle models developed in the area of knowledge engineering are compared to the CIM-software development methodologies and the product life cycle models. There seems to be a close similarity between both areas. This recognized analogy can serve as the theoretical foundations of concurrent engineering. The recent results and tools provided by the AI-planning and scheduling area for the CIM-engineering are briefly sketched with emphasis on the role of declarative programming.<<ETX>>


Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) quickly spread worldwide as a once in a century pandemic in the form of a Coronavirus Disease 2019 (COVID‐19). COVID‐19 has taken only a few months since it was declared pandemic by the World Health Organization in March, 2020 to affect close to 29 million vulnerable people and inflict approximately 1 million deaths across continents.


This experimental project proposes filming of a documentary. Entitled "Made of Affection", the work tells the story of four different families that share the same pillar: affection. The objective of it was to use the documentary´s potential to open a space to think about how relationships of affection are important to people with disabilities. The film was produced from interviews and the monitoring of the routine of those involved, resulting in images that help us to understand the uniqueness of this reality often stereotyped and unknown. The observational and participatory documentary method, used to perform the project, was fundamental to build a trustful relationship between filmmaker and interviewed. The product shows that it is possible through documentary to give visibility to important issues most often ignored by society.


The invention discloses a multi-section-type (FabryPerot) cavity single wavelength laser based on deeply etched grooves. The laser disclosed by the invention is structurally characterized by at least comprising a laser waveguide, a first deeply etched reflecting surface and a second deeply etched reflecting surface which are respectively positioned at two ends of the laser waveguide, and a deeplyetched groove array arranged between the first deeply etched reflecting surface and the second deeply etched reflecting surface, wherein the deeply etched groove array is composed of 2-6 deeply etched grooves; the laser is manufactured on a semiconductor epitaxial wafer, and respectively comprises a lower cladding layer, a quantum well layer, an upper cladding layer and certain auxiliary layers among the lower cladding layer, the quantum well layer, the upper cladding layer layers from bottom to top; and the laser waveguide is divided into a plurality of sections of independent waveguides by the deeply etched groove array, the first deeply etched reflecting surface and the second deeply etched reflecting surface, each section of waveguide is covered with an electrode, and each electrode is respectively injected with a current so as to control the laser wavelength and power. Compared with the background technology, the laser disclosed by the invention has the advantages that the production process is simpler and cheaper due to only once epitaxial growth, the manufacturing error is smaller, the energy consumption for the apparatus operation is less, and the laser line width is narrower.


The aim of this study was to determine the effectiveness of cooperative learning model of type STAD and TPS to solve student learning outcomes in the matter of the reproductive system, the effectiveness of both models can be seen from the results of student learning, teachers' ability to manage teaching and student activities. Design research using pretest-posttest -Control-Group - design, with research subjects high school students at Madura. The result of the study indicates that: (1) the result from both try-outs shows the significant differences from the result of student's learning using STAD and TPS strategies with the significant level 5%, but all of students complete the subject of reproduction system well. (2) The teacher's ability in manage teaching learning process using STAD and TPS strategies is categorized into a good category with the average score to 3.5. (3) The dominant activity of the student in STAD and TPS strategies is doing the student's activity sheets (LKS) in a group. Based on the result of the study, it can be concluded that both cooperative learning model type STAD and TPS are effective in teaching the subject of reproductive system.


The present work has been made to assess a proposal about participating into an extra-curricular sporting activity such as, in this case, basketball. The aim of this is to know if the coach/teacher correctly transmits the information to the players/students in order to assess the teaching procedure in every session. Furthermore, it is intended to observe if values are trained and if healthy habits are generated to prepare young players/students to live within the community. In order to know the final results and elaborate the final conclusions we will make a total of twelve trials in a period of a month, three times per week. Once analyzed those trials we can confirm that the transmitted information was appropriate since the objectives of every session were correctly fulfilled. In the same way, students can demonstrate a positive attitude involving themselves in the training sessions.


In this paper, we study the torsion flow which is served as the CR analogue of the Ricci flow in a closed pseudohermitian manifold. We show that there exists a unique smooth solution to the CR torsion flow in a small time interval with the CR pluriharmonic function as an initial data. In spirit, it is the CR analogue of the Cauchy-Kovalevskaya local existence and uniqueness theorem for analytic partial differential equations associated with Cauchy initial value problems


In the networked control system, all the data packets may not be permitted to be transmitted because of limited bandwidth of the communication network, which may deteriorates the system stability. Multiple-packet transmission method is developed to solve the problem, as the sensor node is time-driven, and the controller and actuator are event-driven. Assuming that the transfer delay is so small that it can be ignored, the networked control system based on multiple-packet transmission is an asynchronous dynamical system with N events, which incorporates continuous and discrete dynamics. The continuous dynamics is governed by differential or difference equations, whereas the discrete dynamics is governed by finite automata that are driven asynchronously by external discrete events. Using the bilinear matrix inequality method, the system's exponential stability is discussed with the status feedback control when the system state is acquirable.


In this study; a total of 150 hyperprolactinemic women their ages (20-50) years are collected from Kmal Al-Samaraee hospital and 50 for normal healthy women used as control. The patients were divided into two groups, those who suffer from primary infertility and those who suffered from secondary infertility, then the 150 patient groups were divided into three age groups (20-30), (31-40) and (41-50) years. Test of fertility hormones, which is (LH and FSH)was done for all patient groups to check the effect of high prolactin levels on the level of other hormones. It was found that there is a significant difference in all hormones concentrations (LH,FSH,PRL) for patients when compared with normal healthy groups hormones, according to type of fertility, both in primary and secondary infertile women. The results show that the prolactin levels in both infertile groups were higher than in normal, healthy, fertile women which lead to decrease the concentration of fertility hormones. Also, it is obvious that the prolactin level in secondary infertile women higher than its level in the primary infertile patients. The results indicate that the higher prolactin levels were in the age group (31-40) years, than of the other two groups.


Male-sterile lines were induced by gamma irradiation and ethyleneimine treatment of seed of Nihonmasari [Superior]. The segregation ratios in the M3 of nine of the 45 families obtained suggested monogenic inheritance of male sterility. Two of these nine lines were crossed with the fertile cultivar Pai-kan-tao. The segregation ratios in the F2 also indicated that male sterility in each line was controlled by a recessive allele at a single locus


Intelligent robot is developing to the cognitive level, emphasizing its ability to understand and interact with the object and environment. This talk discusses the key technologies involved in cognitive robots from three aspects: how intelligent robots can actively perceive, learn and reason the physical world, how to interact with humans and the environment to realize cognitive understanding, and how to make dynamic response according to the changes of the environment. It is pointed out that cognitive learning of intelligent robot is a closed-loop learning process from perception to behavior, and then from behavior to perception. Next, this talk systematically analyzes the wide application of smart operations in the fields of manufacturing, kitchen furniture and art, and introduces the visual tactile sensor developed by our team and its function and performance in robot smart operation. Finally, the future development of intelligent robot is also discussed.


Hearing loss clearly alters the function and connectivity in auditory pathways in the brain. The effects of an auditory receptor lesion on the auditory pathway might be linked to the absence of peripheral stimulation on the first level of the auditory pathway (cochlear nuclei, CN). Loss of stimulation affects the pathway connectivity, at least in the CN, inducing the reorganization of the neural circuits. This reorganization may reduce the efficiency of some deafness therapies, including cochlear implants. Cochlea removal has been shown to be a good model for analysing neuroplasticity in the CN. Three main periods of degeneration and regeneration were found after cochlea removal. During the first week after cochlea removal, early effects included auditory nerve fibre degeneration, and the progressive degeneration of nerve endings on CN neurons. Some CN neurons degenerate. From the second week after cochlea removal a very limited and diffuse expression of GAP-43, a protein linked to developing or regenerating axon growth cones, was found. Expression was observed in small nerve endings connecting cochlear nuclei neurons. One month after cochlea removal, CN were stabilized with a clear reduction of new neuron degeneration. At this time a very relevant expression of GAP-43 was found around remaining neurons, in particular in the ventral cochlear nuclei. Molecular aspects and control of neuroplasticity in cochlear nuclei still remains controversial, even though it is clear that trophic factors and many other substances (i.e. neurotransmitters) have been involved in neuroplasticity.


Teaching techniques and materials that would treat music reading as a process and emphasize the structure of the melodic line were researched, developed, and then tested with 90 fourth grade students, each studying a wind instrument of his/her choice for a year. Control and experimental groups were set up with the groups and their teachers statistically equated. The only variation in treatment of the two groups was in the method of introducing pitches. The experimental group was introduced to pitch through a series of tonal patterns, while the control group learned a new pitch by letter name, fingering, and sound. The study showed that tonal pattern instruction is superior to note identification teaching techniques in development of both sight reading skills and auditory-visual discrimination skills. The experimental treatment was particularly effective with students of low musical ability as measured by the Watkins-Farnum Performance Scale, a test of instrumental sight reading.


A general functional assessment and gait facility has been designed for use in all aspects of measurement of handicap. The functional assessment course contains various features to assess the ability of subjects with different handicaps to sit, take off and apply orthotic or prosthetic devices, climb ramps and steps, negotiate corners, and doors with different locking and opening mechanisms. Incorporated in the middle of the walking section of the course is a force plate to assess the mechanical function of orthoses or prostheses by a force vector visualization system. A visual analogue scoring system of the quality of performance of the various tasks encountered on the functional assessment course as well as the freely selected speed and fastest walking in a straight line has been adopted. This visual analogue score is marked after analysing the video record obtained from a mobile colour camera. The doors, ramps and walking area are wide enough to assess wheelchair use. We have adopted a 'gait graph' for the gait analyses using a 10m straight walkway and measuring the temporal parameters at free speed walking and the fastest walking speed. Energy cost is measured using heart rate monitoring by telemetry on the functional assessment course and during gait analysis. It is proposed to use this facility for the assessment and management of lower limb bracing in children, patients undergoing corrective surgery on the lower limb and for wheelchair users.


Abstract
 This chapter explains emotional intelligence from the perspective of tourism and hospitality service encounters. It shows that emotional intelligence skills are necessary in helping service employees to understand their emotions and manage their emotions effectively in their decision-making while delivering services.


Self‐esteem and well‐being are important for successful aging, and some evidence suggests that self‐esteem and well‐being are associated with hippocampal volume, cognition and stress responsivity. Whereas most of this evidence is based on studies on older adults, we investigated self‐esteem, well‐being and hippocampal volume in 474 male middle‐aged twins. Self‐esteem was significantly positively correlated with hippocampal volume (0.09, P = 0.03 for left hippocampus, 0.10, P = 0.04 for right). Correlations for well‐being were not significant (Ps > 0.05). There were strong phenotypic correlations between self‐esteem and well‐being (0.72, P < 0.001) and between left and right hippocampal volume (0.72, P < 0.001). In multivariate genetic analyses, a two‐factor additive genetic and unique environmental (AE) model with well‐being and self‐esteem on one factor and left and right hippocampal volumes on the other factor fits the data better than Cholesky, independent pathway or common pathway models. The correlation between the two genetic factors was 0.12 (P = 0.03); the correlation between the environmental factors was 0.09 (P > 0.05). Our results indicate that largely different genetic and environmental factors underlie self‐esteem and well‐being on one hand and hippocampal volume on the other.


The aim of this article is analysis of how the Agreement on the withdrawal of the United Kingdom from the European Union governs the mechanisms for monitoring its implementation and resolving disputes. All solutions are based on the international principle of good faith, which obliges the parties of the Agreement to apply it fully. Constant contact between them is ensured by the Joint Committee together with the Special Committees. Any dispute between the parties can only be solved based on the solutions contained in the Agreement, through international arbitration by an arbitration panel. Furthermore, of interest are the provisions governing the specific extension of the jurisdiction of the Court of Justice of the European Union and the practice of the parties to date.


Salmonella fluorescent antibody (FA) positives but cultrual negatives were encountered in pasta samples. Salmonella FA positives were caused by an organism identified as a Lactobacillus plantarum designated strain CT. Brilliant green incorgorated into lactose broth eliminated the false positives. The organism reacted to +3 to +4 with three commercially prepared FA Salmonella poly antisera and with staphylococcal, streptococcal and Pseudomonas FA antisera. The organism also aggulinated in response to a variety of non-FA Salmonella polyvalent antisera (poly A-1, poly D, poly C). L. plantarum/GT absorption of FA Salmonella poly antiserum resulted in reduction of the false positive reaction from +4 to +1. L. plantarum/GT absorption of FA staphylococcal and FA streptococcal antisera resulted in reduction (+4 to +1) in false positive reaction. Fluorescein isothiocyonate (FITC) conjugated normal rabbit immunogloublin G (IgG) strained L. plantarum/GT and Staphyplococcus aureus+4, but Salmonella thompson was not stained. FITC alone produced no false positive staining of the three test organisms. These findings strongly suggest that the FA false positive reaction of L plantarum/GT results not from the organism possessing homologous antigens with Salmonella, but is a consequence of L. plantarum/GT cell surface possessing affinity for the nonantigenic region of the IgG molecule in FA antisera. The data suggest the reaction is analogous to the nonspecific affinity between S. aureus cell wall protein A and the nonantigenic Fc portion of the IgG molecule.


Genetic research in multiple sclerosis (MS) mostly compares patients with MS with healthy controls, but does not differentiate between MS disease courses. We compared peripheral blood gene expression patterns between extremes of MS phenotypes, i.e. patients with mild relapsing‐remitting MS (mRRMS) and primary progressive MS (PPMS).


The documentary features the role and impact of women on the Egyptian Revolution through talking to a female participant, sociologists and a gender specialist.


Businesse Improvement Districts or BIDs have become an important part of most downtown areas in US cities, having beneficial impacts on crime rates and property values. But, if BIDs are so beneficial, then why do some not emerge in certain neighborhoods? In a new study on BID formation in Los Angeles, Wonhyung Lee finds that poorer communities and those with a larger foreign born population are more likely to struggle to form BIDs. She writes that public officials and community workers may need to assess the level of collective vision and action before trying to form BIDs in these neighborhoods.


Objective To analyze the related factors of infective complication in patients with digestive diseases carrying peripherally inserted central catheter(PICC) and provide reference for nursing and prevention of complication in PICC.Methods Clinical data of 142 patinets with digestive diseases on PICC were enrolled,and sex,age,primary diseases,puncturing methods,puncturing site,nursing frequency of catheter,punctured blood vessel,presence of or no complicated angiocardiopathy and diabetes mellitus were recorded,related factors of infective complication in PICC were analyzed by single factor method,influencing factors of infective complication in PICC were analyzed by Logistic regression method.Results Infective complication incidence rate was 18.3%,puncturing methods,puncturing site,nursing frequency of catheter and presence or no complicated angiocardiopathy were related factors of infective complication in PICC;complicated angiocardiopathy and lower nursing frequency were risk factors of infective complication in PICC,and puncturing site of higher elbow joint was protective factor of infective complication in PICC.Conclusions Infective complication in PICC is correlative with puncturing position,nursing frequency and medical complication.Directed nursing intervention should be taken to decrease infective complication in PICC.


Objective To establish suitable diabetic rats models with erectile dysfunction(ED).Methods One hundred and twenty Wistar rats were divided into two groups,the DM groups and the control groups.DM groups were injected intraperitoneally with streptozocin(STZ)(60 mg/kg)to make experimental models of DM.Injected with apomorphine(80 μg/kg),penile erection of the rat models with DM and the controls were observed and noted on the 8th,12th and 16th week from the 4th day of STZ injection.Results The DM ED rat model was established after 8,12 and 16 weeks,the frequency of penis erection in diabetic group was 1.0±0.0,1.0±0.0,1.0±0.0,with which was 2.2±0.8,2.3±0.8,2.0±0.7 in the control groups;the rate of penis erection in diabetic group was only 35%,24%,13% respectively,which was much lower than that 100% in the control groups(P0.01).Conclusion The establishment of DM ED rats models which was induced by STZ injected intraperitoneally is feasible and reliable.


Evolutionary mismatch is, roughly, poor fit between an organism and its environment. Researchers in evolutionary medicine have proposed mismatch as a possible cause for morbidity and mortality in contemporary Homo sapiens populations. Mismatch hypotheses are often taken to provide an evolutionary explanation for the health outcome in question, while simultaneously offering possible interventions for researchers and clinicians to pursue. A problem: fitness outcomes and health outcomes are distinct. Natural selection operates on fitness, not on health per se. There are cases where increased health may not contribute to fitness in the modern environment. I propose an approach for using evolutionary mismatch in clinical research which sidesteps this problem. The gist of the proposal: given structural analogies between environmental causes of morbidity and environmental causes of fitness reductions, evolutionary mismatch can be used as a heuristic to shrink the space through which clinical and public health researchers must search for possible interventions in response to contemporary health problems.


Aim: to analyse the incidence and risk factors of cytomegalovirus (CMV) infection after ASTC. Methods: 129 pts who underwent ASCT in our Institution from June 1997 to June 2004 were analysed retrospectively ( 40 NHL, 66 MM, 8 HD, 8AML, 7CLL). Conditioning regimen consisted in MitoMel in NHL, Melphalan in MM (100–200/m 2 ) and BEAM in AML and CLL. All patients were monitored with Ag pp65 twice weekly from conditioning therapy to hematological recovery. CMV prophylaxis consisted of acyclovir (400 mg p.o. twice daily) and the use of leucocyte-depleted blood products. Following the report of a positive CMV Ag all patients were treated with ganciclovir 5 mg/kg or foscarnet 90 mg/kg twice daily for 2 weeks or until the test was negative. Results: we observed 8 CMV Ag positive: 5 were MM in RP at the transplant and 2 out of 3 NHL were heavily pretreated. Six patients were older than 60 years. The number of CD34 infused was 3.8x10 6 /kg (range 3.1–5.1 ). The mean time for PMN > 500/ul and platelets > 30.000/ul was respectively 11 and 21 days. CMV Ag occurred after a mean time of 21 days (4–45) following ASCT. All patients with a positive CMV Ag were febrile. CMV infection was considered the sole cause of fever in 4 pts; 2 had antibiotic-resistant fever, 1 acute enteritis and 1 pneumonia. The remaining 4 pts had concomitant sepsis: Klebsiella, Pseudomonas, Streptococcus Pneumoniae and Staphylococcus Epidermidis. Seven pts had CMV Ag levels >5/200000 cells and one pt >2/200000 at presentation. The resolution of fever and clearance of CMV Ag occurred after 5.6 days (3–9) from the start of antiviral treatment, but in 2 pts was delayed (respectively 14 and 18 days). Of note, these two pts had the highest CMV Ag levels observed (350 and 961) and one treated with foscarnet developed acute renal failure. Conclusion: 1) CMV infection is an infrequent complication of ASCT( 6,2%) 2) CMV Ag detection was unrelated to the number of CD34 infused and the duration of neutropenia. 3) Pts heavly pretreated, febrile or with sepsis had high rates of CMV reactivation and disease. This subset of pts require more frequent diagnostic evaluation and prompt antiviral therapy.


Several authors have hypothesized that anisogamy would evolve from isogamy by disruptive selection if larger zygotes were selectively favored over smaller zygotes (Parker et al. 1972; Bell 1978, 1982; Maynard Smith 1978). These authors assumed that the fitness of a parent would be proportional to both the number of successful gametes produced and the fitness of the zygotes produced from those gametes. In these models, the fitness of a zygote is assumed to be an increasing function of its volume, and a necessary condition for the evolution of anisogamy is that this relation be steeper than linear. Schuster and Sigmund (1982) have instead suggested that Brownian motion alone is enough to favor the evolution of gamete dimorphism by increasing the rate of encounters between the two types of gametes. Although such theories and their predictions are straightforward, tests of the predictions have been indirect and plagued by ambiguity. Because there is no direct evidence available of how zygote fitness depends on zygote size, Knowlton (1974) and Bell (1978) instead sought out comparative data on adult size in a number of algal groups to provide indirect evidence in support of the theory. They reasoned that unless zygotes also increased in size, increasing adult size would require greater time and energy for development, thereby exposing the zygote to increased hazards and reduced survivorship. This could produce the required disruptive selective pressure for the appearance and maintenance of a macrogamete with cytoplasmic reserves and a microgamete with greater dispersability. We will refer to this as the "adult size" hypothesis. Knowlton (1974) compared gametic condition to colonial cell number at maturity in genera of the family Volvocaceae and found an association between colonies with large numbers of cells and anisogamy. However, Bell (1978) noted several exceptions to this trend. Furthermore, cell number may not be an accurate measure of adult volume, so data on adult cell number are only an indirect test of the adult size hypothesis. In particular, this approach obviously cannot account for patterns observed among the unicellular algae. Bell (1978, 1982) has also argued that increased zygote size facilitates differentiation in those groups with a variety of tissues: "optimal zygote size should increase with vegetative size and complexity" (Bell 1982, p. 491). We refer to this latter idea as the "morphological complexity" hypothesis. Increased cytoplasmic storage does usually accompany morphological complexity, but there are also many exceptions to the expected pattern of increased gamete dimorphism in groups characterized by more cell types. For example, members of the Oedogoniales are all simple filaments yet exhibit oogamy, while Fritschiella and Chaetophora are morphologically complex yet exhibit isogamy. Bell (1978) admits these inconsistencies and suggests that in such cases other factors, such as colony


Carbon fiber (CF) was modified by air plasma at 30 Pa and 200 W with different treatment times. Interlaminar shear strength (ILSS) of CF/BMI composites suggested that air plasma-treated CFs showed better adhesion with BMI resins than the untreated resins; the maximum increment was 20.4% after plasma treatment for 900 s. Meanwhile, we investigated the surface changes of CFs using X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM). The results indicated that air plasma treatment roughened the CF surfaces and improved the polarity of CFs by enhancing the polar group content. These changes were believed to be the major reasons for the improvement of interfacial adhesion. The fracture morphology observed by scanning electron microscopy (SEM) indicated that the fracture failure mode changed from adhesive failure to cohesive failure. After boiling in water for 48 h, the water absorption of the composites was low while the ILSS of the composites retained about 90%, which implied that the CF/BMI composites had good humidity resistance properties.


This paper proposed a crossed dipole antenna with wide axial ratio bandwidth (ARBW), which combines a couple of crossed dipole and four parasitic helical arms (PHAs). In contrast to the previous planar parasitic elements, the PHAs parasitised in vertical contributes a compact size, 0.51\times 0.51\times 0.23\lambda^{3}$. Meanwhile, the PHAs produce three CP modes working with different mechanisms. The simulation shows this work obtains a 57.4% impedance matching bandwidth (IMBW), $\text{VSWR}\leq 2:\ 1.68 \text{GHz} - 3.03 \text{GHz}$, a 51.9% ARBW ranging from 1.85 GHz to 3.07 GHz, and an average gain of about 6 dBic.


The method of calculation proposed in this paper takes into account a stepwise contribution of normal vibration groups to heat capacity. These groups differ in bonds rigidity of structural units of a crystal under study. Calculations presented in the article were carried out using uranylcarbonates of some alkali metals as an example. Comparison of experimental and calculated data of heat capacity shows good agreement in the entire investigated area of thermal stability of compounds including phase transitions.


Hypertension and metabolic disorders evidenced in adults who have been exposed to nutritional insults during early life may be sex-dependent. We evaluated whether blood pressure (BP), cardiorespiratory control and metabolic parameters are affected in female offspring (FO) from dams fed a dyslipidaemic diet during pregnancy and lactation. FO was obtained from dams who received control (CTL) or dyslipidaemic diet (DLP) during pregnancy and lactation. The effects of a maternal dyslipidaemic diet on BP, cardiorespiratory control and biochemical parameters were assessed at 30 and 90 days of age. The experimental protocol based on a dyslipidaemic diet intervention was effective in developing maternal dyslipidemia. At 30 days of age, the FO from dyslipidaemic dams displayed disordered respiratory pattern, enhanced ventilatory response to hypercapnia (P<0.05), increased serum levels of total cholesterol and triglycerides (P<0.05) when compared to CTL female offspring. At 90 days of age, FO from dyslipidaemic dams had augmented BP (P<0.05), exacerbated cardiorespiratory responses to hypercapnia (P<0.05), enhanced pressor responses to peripheral chemoreflex activation (P<0.05), impaired baroreflex (P<0.05) and larger delta variations in arterial pressure after ganglionic blockade (P<0.05). Furthermore, during oral glucose and insulin tolerance tests, FO from dyslipidaemic dams exhibited altered glucose tolerance and insulin sensitivity (P<0.05) when compared to FO from CTL dams. Altered breathing linked to enhanced central and peripheral chemosensitivity, impaired baroreflex and augmented sympathetic tone may be predisposing factors for increased BP and metabolic disorders in female offspring from dyslipidaemic dams.


This article reveals that the literary salon of Suzanne Necker didn't form the public sphere in the same way as Habermas defined it. First of all, the opposition to the royal court, to the religion and to the social order did not dominate the eighteenth century parisian salon. Moreover, this salon wasn't open to all the merits. The merit without fame wasn't invited to this salon. Finally, the dialogue in the salon was carefully controlled by the salonnieres. They controlled the subject of the discussion in order not to defy social convention and imposed their own strict rules on their guests. Therefore, salon didn't deserve the name of "bourgeois republic". But that does not mean that the salon of Suzanne Necker didn't play any public role. In the eighteenth century when the established moral and religious principles were doubted and threatened, she tried to keep the discussion about the coming society from going too far. She made, consciously or not, every effort to achieve this goal. The salon is more likely to control the ongoing change rather than to cause it. In effect, it preferred literature to pending issues, payed attention to the selection of the guests and emphasized the politeness and discipline. Nevertheless, Suzanne Necker did not assert the public status of women and did not struggle to overcome the prevalent idea of the sex. On the contrary, she recognized the gender distinction and agreed to confine the role of woman within domestic life. For her, the salon must remain the private sphere. Therefore, the life as a salonniere and as a supporter of the charity hospital did not conflict with the fact that she refused firmly the title of author.


Discovered in the context of card shuffling by Aldous, Diaconis and Shahshahani, the cutoff phenomenon has since then been established in a variety of Markov chains. However, proving cutoff remains a delicate affair, which requires a detailed knowledge of the chain. Identifying the general mechanisms underlying this phase transition -- without having to pinpoint its precise location -- remains one of the most fundamental open problems in the area of mixing times. In the present paper, we make a step in this direction by establishing cutoff for Markov chains with non-negative curvature, under a suitably refined product condition. The result applies, in particular, to random walks on abelian Cayley expanders satisfying a mild degree condition, hence in particular to \emph{almost all} abelian Cayley graphs. Our proof relies on a quantitative \emph{entropic concentration principle}, which we believe to lie behind all cutoff phenomena.


* Corresponding auther address: Huaqing Cai, ASP/ ATD, National Center for Atmospheric Research, Boulder, CO 80307; e-mail: email@example.com Fig. 1. Satellite imagery superimposed on surface analysis at 2230 UTC. The small box in the Oklahoma Panhandle represents the IHOP Intensive Observation Domain (IOD) from 2100 to 2330 UTC. A and B denote the two storms initiated around 2230 UTC.


Since the revolution of 1918 the Hungarian Chamber of Magnates, noted among upper chambers for its longevity, has been in a state of suspended animation. Unlike the lower house, the Chamber of Deputies, which disappeared under the tidal wave of revolution at the outset of the Karolyist régime, it never was formally dissolved. Both houses of the Hungarian parliament, yielding to political realities, suspended their sessions and disbanded, many of the members of the upper chamber scurrying to regions under Allied occupation for protection against possible excesses of the revolution. Following the brief interlude of extra-constitutional Karolyist republicanism, under the legislative auspices of the Hungarian National Council, came the communist revolution which swept before it all remnants of the older constitutional structure. But not for long. On the collapse of the Hungarian Commune it became the onerous task of the Allied Governments to find, or to create, a constituent authority capable of assuming unreservedly the obligations of peace-making and domestic reconstruction. The First National Assembly, elected by decree of Stephen Friedrich, then the liaison between the Hungarian nationalists and the Great Powers in Paris, was the result. This single-chambered body, distinctly smaller than the old Chamber of Deputies because of the territorial reduction of Hungary, became, for the purposes of the Allied Governments, the sole repository of national power, and was acknowledged by them, as well as by the nation itself, to have constituent authority.


This paper intended to control a DC microgrid in islanded operation mode using decentralized power management strategies. The DC microgrid under study included a wind turbine generator (WTG), photovoltaic (PV), battery energy storage system (BESS) and dc constant power load. According to the newly proposed strategy, each of distributed generation sources of energy and battery energy storage system can be deployed independently within any controlled microgrid through the droop method. Proposed I/V characteristic curve could be regulated locally and in real-time based on the available power of DGs and the battery state of charge (SOC), to synchronize the module performances independently and establish the power balance in the DC microgrid. Proposed strategy for the battery enables the system to supply independently the power required for the load demand when the DGs are not capable of supplying the required power to the load. This can maintain the common bus voltage within the allowable range and establish the power balance in the DC microgrid. The proposed control strategy was applied locally and without dependency on telecommunication links or any centralized energy management system on each of the distributed generation modules and battery independently. The newly proposed power management strategy was simulated through the implementation of a low voltage DC microgrid in MATLAB/SIMULINK where its performance was evaluated.


The Stretch-Fold-Shear (SFS) operator is a functional linear operator acting on complex-valued functions of a real variable x on some domain containing in It arises from a stylized model in kinematic dynamo theory where magnetic field growth corresponds to an eigenvalue of modulus greater than 1. When the shear parameter α is zero, the spectrum of can be determined exactly, and the eigenfunctions corresponding to non-zero eigenvalues are related to the Bernoulli polynomials. The spectrum for has not been rigorously determined although the spectrum has been approximated numerically. In this paper, a computer-assisted proof is presented to provide rigorous bounds on the leading eigenvalue for , showing inter alia that has an eigenvalue of modulus greater than 1 for all α satisfying , thereby partially confirming an outstanding conjecture on the SFS operator.


Objective To observe the effect of astragalus polysaccharides(APS) on proliferation and nitric oxide(NO) production of endothelial progenitor cells(EPCs) from peripheral blood in patients with type 2 diabetes mellitus(T2DM).Methods Total mononuclear cells were isolated by Ficoll density gradient centrifugation.After 7 days of culture,EPCs were characterized,the effect of APS on EPCs proliferation was observed.EPCs were treated with various concentration and different time culture of APS,then treated with LY294002(PI3K inhibitor),then the NO level was measured.Results APS could promote the proliferation of EPCs in T2DM,and increase the endothelial NO production in a dose and a time-dependent manner.LY294002 prevented the NO production induced by APS.Conclusions The rat tail collagen can be a more cheaper replacement of the fibronectin to culture the EPCs from peripheral blood in patients with T2DM.Treatment with APS can increase the NO production and markedly promote the proliferation of EPCs in T2DM,LY294002 prevents the NO production induced by APS.


AIM: The purpose of this study was to evaluate daycare educators' knowledge on oral health, malocclusions and non-nutritive habits and how to address these issues. Educators were also investigated on whether or not they had received previous instructions on oral health and the quality of such information. MATERIAL AND METHODS: A survey was conducted using a questionnaire, given to daycare educators of Araraquara (SP, Brazil). The structured questionnaire had close-ended questions, and was divided into three sections according to subject matter. RESULTS: Based on the analyzed questionnaires (n=143), most educators showed reasonable knowledge on oral health (72%) and non-nutritive habits (52.4%), although 89.5% of them had received previous instructions on the subject. Chi-square test showed no association between the level of knowledge among educators and the variables: age, type of school and self assessment of knowledge. CONCLUSIONS: These professionals need additional information about oral health in order to address these topics through educational practices, since educators are the best suited professionals to teach and motivate children.


Recently indoor air pollution caused by exposing hazardous chemicals (VOCs, formaldehyde) due to undiscriminated use of new construction materials and air-tightness to save energy is becoming a big issue. We have developed technologies to estimate the amounts of contaminants from constructions materials and method. We have further developed construction technologies to reduce and characterize these contaminants.The developed technologies were then refined to eliminate defects through considering field applicability.


This work describes a novel solution to the mapping problem for a mobile robot moving in an unknown indoor environment. The proposed mapping technique provides a cells-based covering of the environment boundaries. No assumptions are made on the cells placement, therefore the covering is not forced to stay in a regular scheme, like in the grid-based approach. The main idea is to estimate the probability mass function of finding an environment boundary point in a given cell, and to use the obtained approximation of these points to build an environment map. The resulting mapping algorithm can be either used alone to solve the Simultaneous Localization and Mapping (SLAM) problem, or it can be used in series to an existing given SLAM algorithm to improve its performance. Numerical simulations show the effectiveness of the proposed mapping and SLAM strategies by comparing them with other SLAM techniques from the literature.


Objective:To analyze the clinical efficacy of somatostatin in acute pancreatitis.Method: 88 patients with acute pancreatitis were randomly divided into treatment group and control group, control group(44 cases) was given fasting, gastrointestinal decompression, maintaining water, electrolyte and acid-base balance, the routine use of antibiotics, adding blood volume, maintaining parenteral nutrition and other symptomatic supportive treatment.At the same time low molecular weight dextran, Danshen, proton pump inhibitors, such as intravenous infusion were applied.Treatment group(44 cases) was treated with somatostatin 3 mg in 5% glucose intravenous injection in addition.The abdominal pain and abdominal tenderness disappeared deep time and the clinical cure rate,cure time and mortality were compared.Result:In the control group, abdominal pain and abdominal tenderness disappeared time(88.3±3.6) h and(170.6±39.1) h comparing with the treatment group(49.1±12.1) h,(102.1±38.3) h were with statistical significant(P0.05).Cure rate was 81.82%(36/44) in the control group, cure time was(23.6±4.9) d, mortality was 18.18%(8/44).In the treatment group: the cure rate was 97.73%(43/44), cure time was(16.3±5.5) d, the mortality rate was 2.27%(1/44).Differences between the two groups had statisticalsignificance(P0.05).Conclusion:The therapeutic effect of somatostatin on acute pancreatitis is significant,it can control the disease progresses in some extent.


Significance Lanthanide borides constitute an important class of materials with wide industrial applications, but clusters of lanthanide borides have been rarely investigated. It is of great interest to study these nanosystems, which may provide molecular-level understanding of the emergence of new properties and provide insight into designing new boride materials. We have produced lanthanide boride clusters and probed their electronic structure and chemical bonding. Two Ln2B8− clusters are presented, and they are found to possess inverse sandwich structures. The neutral Ln2B8 complexes are found to possess D8h symmetry with strong Ln–B8 bonding. A unique (d–p)δ bond is found to be important for the Ln–B8–Ln interactions. The Ln2B8 inverse sandwich complexes broaden the structural chemistry of the lanthanide elements and provide insights into bonding in lanthanide boride materials. While boron forms a wide range of metal borides with important industrial applications, there has been relatively little attention devoted to lanthanide boride clusters. Here we report a joint photoelectron spectroscopy and quantum chemical study on two octa-boron di-lanthanide clusters, Ln2B8− (Ln = La, Pr). We found that these clusters form highly stable inverse sandwich structures, [Ln–B8–Ln]−, with strong Ln and B8 bonding via interactions between the Ln 5d orbitals and the delocalized σ and π orbitals on the B8 ring. A (d–p)δ bond, involving the 5dδ and the antibonding π orbital of the B8 ring, is observed to be important in the Ln–B8 interactions. The highly symmetric inverse sandwich structures are overwhelmingly more stable than any other isomers. Upon electron detachment, the (d–p)δ orbitals become half-filled, giving rise to a triplet ground state for neutral La2B8. In addition to the two unpaired electrons in the (d–p)δ orbitals upon electron detachment, the neutral Pr2B8 complex also contains two unpaired 4f electrons on each Pr center. The six unpaired spins in Pr2B8 are ferromagnetically coupled to give rise to a septuplet ground state. The current work suggests that highly magnetic Ln…B8…Ln inverse sandwiches or 1D Ln…B8…Ln nanowires may be designed with novel electronic and magnetic properties.