(57) Abstract: The present invention is an ion-exchange resin as a carrier (e.g., methacrylic acid polymer crosslinked with divinyl benzene) were used, to the formulation of oral liquid preparations of quinolones or derivatives thereof. Thus, there is no extreme bitterness of the quinolones oral liquid formulation. In particular, aqueous pharmaceutical compositions of the present invention contains the following: a. 0.01 wt% to 30 wt% of the quinolone compound or derivative thereof; b. 0.01 wt% to 60 wt% of the ion exchange resin; c. Pharmaceutically acceptable excipients to equal 100%.


When designing interactive web applications and services, understanding the situated nature of interaction and investigating technology appropriation experiences in the context of real-world use deserve special attention. In this paper, we report on experiences with technology appropriation of an e-Deliberation platform that we designed to support collaborative interpretation in an art gallery. Our qualitative study is based on interviews with 23 participants to explore a) visitors' practices when commenting on and interpreting art and b) how these practices are shaped by interaction with an e-Deliberation platform for collaborative writing that imposes strict regulations. An analysis of 12 hours of interview data yielded two particular appropriation practices related to the demand to satisfy additional visitors' communication needs, such as exchanging their ideas and thoughts face-to-face before writing an interpretation. Although the designers anticipated these specific needs, users also appropriated the e-Deliberation platform in unanticipated ways. These practices lead to a better understanding of the situated nature of ex-situ interaction when using interactive web applications to support remote collaboration in the art gallery context.


We present Midas, a system that uses complex data processing to extract and aggregate facts from a large collection of structured and unstructured documents into a set of unified, clean entities and relationships. Midas focuses on data for financial companies and is based on periodic filings with the U.S. Securities and Exchange Commission (SEC) and Federal Deposit Insurance Corporation (FDIC). We show that, by using data aggregated by Midas, we can provide valuable insights about financial institutions either at the whole system level or at the individual company level. The key technology components that we implemented in Midas and that enable the various financial applications are: information extraction, entity resolution, mapping and fusion, all on top of a scalable infrastructure based on Hadoop. We describe our experience in building the Midas system and also outline the key research questions that remain to be addressed towards building a generic, high-level infrastructure for large-scale data integration from public sources.


[Objective]This study aims to get a picture of the status quo of nursing in the countryside through investigation,to analyze existing problems and put forward some suggestions.[Methods]This study adopted surveys,field investigation,and statistical analysis.[Results]68.3% of the nurses graduated from Vocational Secondary Schools,while 10.9% had no degrees;80.5% of the nurses did not participate in out-of hospital vocational studies,99.1% did not have further education,and 13.1% of the hospitals had never organized vocational studies;31.3% of the nurses had no certificate,and 27.8% did not register;21.1% of the nurses were not in post;72.2% of the technical operations were substandard.[Conclusion]There are kinds of insecure factors in nursing in countryside hospitals.Thus,it is of great urgency to implement secure nursing measures,introduce and cultivate nursing talents and practise legally.


Decline curves of oil production can be analysed by a method based upon the study which has been explained in the papers.1, 2) The following features characterize exploitation of old oil fields in Japan, and these facts enable the precise analysis of decline curves: (1) generally, constant producing method was adopted for all of the wells in one oil field, (2) production restriction was not considered, (3) secondary recovery method was not introduced, (4) oil production of all wells was recorded comparatively acculately from the beginning of exploitation, and (5) too narrow well spacing was applied in some oil fields.Results of the analyses are summarized as follows:(1) It is assumed that in most oil fields in Japan the solution gas is main energy of oil production.(2) Caused by oil production, the reservoir pressure decreases indicating approximately similar value at all points in the reservoir. In most oil fields there is no fault which interrupts flow of fluid.(3) There is a definite relationship between reservoir structure and value of (effective permeability of oil)×(thickness of reservoir). Generally, there is more oil at central part of a reservoir than at marginal part.(4) Caused by greater solubility of gas to oil, some wells, during their initial stages, indicate greater production rate and greater coefficient of production decline curve than average values.(5) Unusual increase of coefficient of decline curve occurs frequently at wells located marginal place of a reservoir or at wells of a depleted reservoir.(6) When distance between wells is greater than at least 60 metres, there is no relationship between well spacing and production rate of oil and between well spacing and coefficient of production declirle curve.(7) As mentioned above, results obtained from the study on production decline curve provide knowledge relating to physical properties of oil reservoirs which can not be obtained otherwise: Therefore, this study provide valuable data for economical exploitation of oil field, especially for problem of well spacing and for secondary recovery.


The last decade has seen a dramatic increase in academic interest in the study of European integration among Nordic scholars. When the authors of this article initially became interested in European integration as Ph.D. candidates in the early to mid-1990s, there were comparatively few scholars writing consistently on aspects of European integration. There were – in reality – only a handful of 'leading' authorities, such as Carl-Einar Stålvant (Sweden), Martin Sæter (Norway), Esko Antola (Finland), Thomas Pedersen (Denmark) and Gunnar Helgi Kristinsson (Iceland) to name some of the few. In 2002, as we survey the amount of scholarly research on the study of European integration today, the difference is stark. Of course, part of the reason why Nordic scholars became more genuinely interested in EU affairs is precisely because three of the Ž ve Nordic countries applied to join the Union in the early 1990s and, since 1995, Finland and Sweden have joined Denmark as full members of the European Union (EU). In short, there is a degree of selfinterest at work as European integration has increasingly found its way into Nordic domestic politics, and highlighted even further the fact that the traditional demarcations between political science and international relations have become increasingly blurred. However, the intention of this article is not to discuss the reasons for the expansion of interest in EU affairs from Nordic scholars. Rather, it is to act as a commentary on the various contributions which such scholars are making to the wider study of European integration. Given the brevity of this article, it is impossible to cover all of the research


The paper made unary linear regression and structure deviation degree analyses with the data of Shanxi province in China from 1992 to 2010. The results show that when the coal output increases by 1% , the employment will increase by 1.202%. And the structure deviation degree in the coal industry fell from-0.11 to-0.56 between 1992 and 2001, then it aggrandized to - 0.15 in 2010. Which presented a note of discord surfaced during industrial structure and employment structure adjusting in Shanxi province. This suggests that there are the disguised unemployment within the coal industry. So this paper emphasizes that the government should implement the coal property right reform policy, and simultaneously develop effective measures to guide the workers to flow from the coal industry to the other secondary industries or the third industry.


This paper deals with the problem of the output voltage regulation in a buck converter for an unknown constant power terminal (CPL) which generates a nonlinear dynamical model that requires an efficient control technique. An extended feedback linearization (EFL) approach is proposed to regulate the voltage provided to the CPL. The main characteristic of the EFL control is that it is based on the linearization of the dynamical model around the desired operative point, making it equivalent in this point to the classical approximated feedback control design. However, the EFL, even if designed with the linearized model, provides a nonlinear feedback control law that extends the action area near the operating point with better performance than linear controllers. To estimate the unknown load value, the estimation technique known as the inverse and invariant approach is applied with the main advantage that the load estimation has exponential convergence to the real value of the CPL. Numerical simulations in the PLECs software for MATLAB/Simulink reveal the effectiveness of the proposed EFL control compared to the exact feedback linearization controller.


Cysticercosis is a disease caused by the larvae of Taenia sp. worm which have serious impact to human. One of many caused of cysticercosis is population and maintenance system in a region. TTS is one area that has the highest number of pigs in the province. This study aims to determine the cysticercosis of pig at the slaughterhouse in So'e and to know the relation between cycstisercosis and maintenance system. The study was conducted to 14 pigs. The examination performed on the tongue muscle, masseter muscle and liver. The test were conducted postmortem examination and laboratory test. Laboratry test conducted to identify morphological of skoleks. The changes in the organs of the result of postmortem examination continued to cysticercus identification. And the laboratory result showed that 2 pig positive cysticercosis caused by cysticercosis cellulosae. It can be included that the cysticercosis connected with maintenance system. However, the cysticercosis of pig in So'e still required program by relevant agencies to eradicate this disease.


A method of improving the performance of X-band Doppler radars for ground transport vehicles is presented. The technique utilizes small metallic reflectors placed directly below the guideway surface. From the results of preliminary laboratory and on-road tests it is concluded that improved accuracy of on-board position and velocity measurements result.


The analysis of random response and failure probability of LRB isolated structure under minor earthquakes investigated is investigated.A non-proportionally damped MDOF model is used based on the linearized parameters which are used for practical design,and an analytical expression of the "pseudo" response amplitude vector is derived using pseudo excitation method(PEM).The elastic limit state is used for deriving the performance equation,and the maximum interstory drift is adopted as the performance index of the superstructure.The conditional failure probability,reflecting the probability of cracking under minor earthquakes,is calculated using first-order reliability method(FORM).With a 7-story isolated RC frame chosen as numerical example,the result of random response by the proposed method are compared with other three methods,and verified with Monte Carlo dynamic simulation.The result shows that the proposed method has good accuracy.


Rectus abdominis muscles are supplied mainly by superior and inferior epigastric arteries, forming an arcade between them. The ligation of one of them during a surgical intervention usually has no clinical repercussions. However, when both arteries flow are interrupted, there is another clinical scenario.

 We describe the case of a 74 years-old woman who was admitted for an elective surgery of fourth recurrence of a midline eventration (M2-5W3 European Hernia Society Classification). We treated using preoperative botulinum toxin and Rives-Stoppa surgical technique. On the second postoperative day, the patient suffered a cardiorespiratory arrest due to a pulmonary embolism, therefore anticoagulation was necessary. After anticoagulation the patient showed severe anemia (Hemoglobin 5 g/dL) and tomography computed scan images revealed a big hematoma of the abdominal wall with active bleeding.

 Embolization of both epigastric, right mammary and left pectoral arteries was performed by interventional radiologists. After 12 days, the patient showed cutaneous surgical wound dehiscence and serohematic foul-smelling fluid. We detected necrosis of the rectus muscles when we debrided the wound. It was treated with daily cures and vacuum therapy without mesh removal, achieving a progressive closure. After six months of follow-up, there are no signs of recurrence.

 Ischemia of the rectus muscles is a severe complication after eventroplasty that can be treated with debridament of necrotic muscle and vacuum therapy, without removal of mesh if it is sufficiently extended along the healthy abdominal wall and cover the necrotic defect.


Women who smoke, deliver significantly smaller infants. These infants have reduced levels of the vasodilator endothelial nitric oxide synthase (eNOS) levels in the umbilical vessels, which may reduce fetal growth. Serum cotinine, the degradation product of nicotine, can be used to determine the level of tobacco exposure. Newborns of environmental smokers are suggested to be smaller and shorter in weight, length, and head circumference. eNOS levels have not yet been studied in these infants. We investigated the existence of a relation between maternal environmental tobacco smoke exposure, eNOS activity, concentration, and birthweight.


In this article, a conversation between Old Helsinki Slang (OHS) speakers recorded in 1965 is examined. A notable feature of OHS is the heavy use of Swedish-based or otherwise un-Finnish words although it mostly follows the grammar of colloquial Finnish. e sample that is analyzed consists of free speech, and it lasts 65 minutes. If uncertain items are taken into account, then the proportion of borrowed lexical items in the data is 29–32%. Function and content words in OHS di er markedly in their etymological origin as the function words are overwhelmingly Finnish. Although OHS has some phonological and phonotactical features that are strikingly "un-Finnish," it is apparent that these features have been adopted along with loanwords. While some morpho-syntactical features in OHS di er from those of Standard Finnish, they are widely known in Finnish dialects and colloquial Finnish and, therefore, cannot be interpreted as innovations in OHS. Morpho-syntactically, the sample can easily be interpreted as a variant of Finnish. While the proportion of borrowed words in OHS is not exceptional among the world's languages, it is in any case notable; furthermore, core borrowing is common and even basic vocabulary is the product of borrowing. Roughly 40% of the vocabulary of OHS can be de ned as slang, a proportion unknown in Finnish dialects or in Standard Finnish. is slang vocabulary is overwhelmingly borrowed, and it can be seen as the most apparent contact feature of OHS. It has made this variety of urban speech virtually incomprehensible to contemporary dialectal or Standard Finnish speakers.


Nanomotors consisting of single protein molecules are abundant in living systems. Here we report a nanomotor made of a single DNA molecule. The DNA nanomotor can adopt two distinct conformations, intramolecular tetraplex and intermolecular duplex. The nanomotor switches between the two conformations through alternating DNA hybridization and strand exchange reactions, which enables the nanomotor to perform an inchworm like extending−shrinking motion. When the single molecule nanomotor is loaded with two organic molecules, a fluorophore and a quencher, the motion can be viewed in real time by monitoring the fluorescent signal. The DNA nanomotor functions efficiently both in solution and on nanoparticle surfaces. Its simple yet stable structure, convenient operation, and high efficiency may make the DNA nanomotor practically useful for powering nanosystems in future applications.


We investigate the surface critical field Hc3 of MgB2 in the clean limit using the two-band Ginzburg–Landau (GL) theory. When the surface of a superconductor coincides with one of the crystallographic planes and is parallel to the external magnetic field , the ratio Hc3/Hc2 (where Hc2 is the upper critical field of MgB2) exhibits strong temperature dependence. When the surface of a superconductor coincides with the bc plane and is parallel to , the ratio depends not only on temperature, but also on the angle between the c axis and . However, for single-band superconductors this ratio is constant.


Floristic research investigating the presence and phytocoenological
 differentiation of ruderal vegetation, and how it is conditioned structurally
 and anthropogenically, was undertaken over a period of several years
 (2007-10) in the south Srem region. The ruderal flora of the research area
 comprised 249 plants categorized into 63 families, of which the most frequent
 were: Asteraceae (36), Poaceae (29), Fabaceae (18), Lamiaceae (15),
 Polygonaceae (15), Brassicaceae (11) and Rosaceae (11). Three ruderal
 communities are analyzed in this work: Asclepietum syriacae Kojic et al.,
 2004, as well as Chenopodio-Ambrosietum artemisiifoliae ass. nova and
 Amorpho-Typhaetum ass. nova, which are described for the first time. It was
 established that the level of moisture at the habitat, anthropogenic factors,
 and the immediate proximity to cultivated areas had the most pronounced
 effect on the differentiation of the researched vegetation.


Novel test bench techniques are required to cope with afunctional test complexity which is predicted to grow muchmore strongly than design complexity. Our test benchapproach attacks this complexity by using a stronghierarchical architecture, application domain-independentsynchronization, reusable modules, and easy incrementalextendability based on table-driven techniques. In addition,the integration of VHDL/C co-simulation under the controlof the test bench makes it possible to use the hardware modelfor software testing and vice versa and thus enables extremereductions in test bench coding. The efficiency of our testbench has already been demonstrated in several industrialprojects, among them a four-ASIC ATM board with oneembedded core and one external micro controller.


Polar areas are the most sensitive targets of climate change. From this perspective, the continuous monitoring of the cryosphere represents a critical need, which, now, we can only partially supply with specific satellite missions. The integration between remote-sensed multi-spectral images and field data is crucial to validate retrieval algorithms and climatological models. The optical behavior of snow, at different wavelengths, provides significant information about the microphysical characteristics of the surface in addition to the spatial distribution of snow/ice covers. This work presents the unmanned apparatus installed at Ny Ålesund (Svalbard) that provides continuous spectral surface albedo. A narrow band device was compared to a full-range system, to remotely sensed data during the 2015 spring/summer period at the Amundsen-Nobile Climate Change Tower. The system was integrated with a camera aimed to acquire sky and ground images. The results confirmed the possibility of making continuous observations of the snow surface and highlighted the opportunity to monitor the spectral variations of snowed surfaces during the melting period.


Introducing Bach flower remedies using Bach flower remedies learning the remedies the remedies - fear and worry the remedies - depression and hope the remedies - confidence the remedies - when something happens the remedies - relationships the remedies - action and inaction groups and difference widening the net troubleshooting glossary and repertory learning more useful addresses.


The government is encouraging small businesses to improve product quality by adjusting its product in accordance with the Standar Nasional Indonesia (SNI-Indonesian National Standardization). Halal is one aspect of quality, especially in the food and beverage products, which is considered in Indonesia, due to most of Indonesian is Moslem. This research was aimed to develop halal marketing strategies for specific SME (Small Medium Enterprise) that produced "wedang uwuh" beverage and gluten-free flour in Yogyakarta. The SME is called SMEs Progress Jogja. The marketing strategy in SMEs Progress Jogja was developed using a questionnaire that distributed to stakeholders. The tools which for analysis were SWOT matrix and QSPM. There are three expected strategies by the SMEs Progress Jogja that should be selected. The strategies were expanding the market share (especially by exploiting the defense of government), developing/increasing product variation, and also preserving the quality and the halal requirement of products. Then, the chosen strategy that was selected by using the priority matrix QSP is to expand market share.


Cathodoluminescence (CL) technique, as a special petrologic tool, has been applied to the studies of uranium hosted sandstone from No.512 uranium deposit located in Xinjiang Autonomous Region, Northwest China. The detrital grains including quartz, feldspar, debris and cements display distinguishing CL properties. The quartz grains mainly demonstrate brown and dark blue CL, feldspar grains demonstrate blue and bright blue CL, calcite cement displays bright yellow-orange and orange-red CL with significant CL zoning, while the debris, mud and sand cements have dark red CL, multicolor CL or non-luminescence. The characteristics of overgrowth, fracture healing, and the original contact relations of detrital grains appear much more significant with CL than that with conventional visual methods. Much more information can be contributed by CL technique to decipher the provenance area, to explain the cementation, consolidation and other diagenesis processes of sandstone. The CL technique also provides an efficient tool for identifying detrital grains and cements, and for more precisely estimating the proportions of various detrital grains and cement components in sandstone. The CL emission of uranium hosted sandstone revealed the existence of radiation-damage rims of quartz grains at the places with a little or no uranium minerals nearby, which may imply a uranium-leaching episode during the diagenesis of sandstone.


Previous studies have shown that the amplitude of the vibration of a piezoelectric (PZT) device produces an oscillating flow that changes the hamber volume along with a curvature variation of the diaphragm. In this study, an actuating micro-diaphragm with piezoelectric effects is utilized s an air-flow channel in proton exchange membrane fuel cell (PEMFC) systems, called PZT-PEMFC. This newly designed gas pump, with a iezoelectric actuation structure, can feed air into the system of an air-breathing PEMFC. When the actuator moves outward to increase the cathode hannel volume, the air is sucked into the chamber; moving inward decreases the channel's volume and thereby compresses air into the catalyst layer nd enhancing the chemical reaction. The air-standard PZT-PEMFC cycle is proposed to describe an air-breathing PZT-PEMFC. A novel design or PZT-PEMFCs has been proposed and a three-dimensional, transitional model has been successfully built to account for its major phenomena nd performance. Moreover, at high frequencies, PZT actuation leads to a more stable current output, more drained water, higher sucked air, higher ydrogen consumption, and also overcomes concentration losses. 2008 Elsevier B.V. All rights reserved.


Biologic and target synthetic disease modifying anti-rheumatic drugs (bDMARDs and tcDMARDs) are recommended to control RA disease activity, pain and steroid use. Following randomized clinical trials (RCTs) and their post-hoc analyses, the Janus Kinase Inhibitor tsDMARDs BARI was superior to reference bDMARD Adalimumab in reducing disease activity, pain and functional disability. In addition, BARI monotherapy also determined more significant pain reduction and functional improvement when compared to Tocilizumab monotherapy (3).to confirm RCT results in a real-life clinical setting, with focus on disease activity, pain, functional disability and steroid tapering, when comparing BARI to bDMARDs for the treatment of active RA.RA patients starting BARI or a bDMARD for active RA were retrospectively evaluated from June 2019 to June 2020. Disease activity (DAS28CRP, SDAI, CDAI), pain visual analogic scale (pain_VAS), functional disability (HAQ) assessments and mean prednisone dosage (pred_dose) were collected at baseline (BL), 3 months (3M) and 6 months (6M) after BARI/bDMARD initiation. The changes of the outcome measures were evaluated between BL-3M, 3M-6M and BL-6M, as well as between BARI and bDMARDs groups. Finally, we assessed the variables associated with prednisone tapering in the whole population.90 out of 100 RA patients evaluated (baseline: age 57±12 years, disease duration 131±100 months, DAS28PCR 4.8±1.0, pain_VAS 61±23 mm, prednisone dose 5.5±5.3 mg) were eligible for the study; 49 received BARI and 41 bDMARDs (17 abatacept, 12 TNF inhibitors, 11 tocilizumab, 1 rituximab). At BL, the two groups did not differ statistically in terms of age, sex, disease duration, disease activity, pain_VAS, previous bDMARD failure or ts/bDMARD naive, concomitant conventional synthetic DMARDs treatment, pred_dose. Both BARI and bDMARDs determined a significant reduction in activity scales and HAQ when comparing BL-3M and BL-6M, with only pain_VAS and pred_dose showing a significant decrease in the 3M-6M interval. When comparing the two groups, BARI showed a significantly higher reduction of pred_dose (-3.2±5.1 vs -1.7±3.7 mg at BL-3M, and -4.1±5.3 vs -1.9±4.6 mg at BL-6M), which was not significant after adjusting for BL pred_dose. No other difference was seen when the two groups, including the numerically higher reduction of pain_VAS in the BARI group (-29±28 vs -20±27 mm at BL-3M and -35±25 vs -30±28 mm at BL-6M comparison). The analysis of the predictors for steroid tapering (Δmean_pred) in the two intervals, showed that BL DAS28PCR, DAS28PCR BL-3M change and BL pred_dose were associated with BL-3M Δmean_pred, while 3M pain_VAS and 3M pred_dose were associated with 3M-6M Δmean_pred.Although limited by the small samples and the retrospective nature, our real-life comparison shows similar efficacy of BARI and bDMARDs in terms of disease activity control, functional disability and pain. In addition, the treatment with BARI or bDMARD did not influence the steroid tapering, which was driven mostly by its initial dose, disease activity and pain. Larger real-life multi-center studies are warranted to confirm our results.[1]Taylor PC et al. Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis. N Engl J Med. 2017 Feb 16;376(7):652-662.[2]Fautrel B et al. Effect of Baricitinib and Adalimumab in Reducing Pain and Improving Function in Patients with Rheumatoid Arthritis in Low Disease Activity: Exploratory Analyses from RA-BEAM. J Clin Med. 2019 Sep 5;8(9):1394.[3]Fautrel B et al. Comparative effectiveness of improvement in pain and physical function for baricitinib versus adalimumab, tocilizumab and tofacitinib monotherapies in rheumatoid arthritis patients who are naïve to treatment withLaura Cometi: None declared, Cosimo Bruni Speakers bureau: Actelion, Consultant of: Eli Lilly, Grant/research support from: Fondazione Italiana Ricerca sull'Artrite (FIRA), Gruppo Italiano lotta alla Sclerodermia (GILS), New Horizon Fellowship, European Scleroderma Trials and Research (EUSTAR) group, Foundation for Research in Rheumatology (FOREUM)., Lorenzo Tofani: None declared, Giulia Tesei: None declared, Francesca Nacci: None declared, Ginevra Fiori: None declared, Francesca Bartoli: None declared, Marco Matucci-Cerinic Speakers bureau: Biogen Italia, Actelion, Bayer, Boehringer Ingelheim, CSL Behring, Eli-Lilly, Consultant of: Biogen Italia, Actelion, Bayer, Boehringer Ingelheim, CSL Behring, Eli-Lilly, Grant/research support from: Biogen Italia, Actelion, Bayer, Boehringer Ingelheim, CSL Behring, Eli-Lilly,


The note gives a watertight confirmation of the E-infinity Cantorian theory results for ordinary and dark cosmic energy density of the universe and respectively. The computation is fundamentally based on a golden mean fusion function that goes back to the highly original anyon proposal of F. Wilczek.


Industry 4.0 is a smart factory where smart digital devices are connected and that communicate with raw materials, semi-finished products, products, machines, tools, robots and people. The pace of technological change in the banking sector and the current monetary environment in the industrial era 4.0 is very high. Realizing these opportunities, this paper aims to describe the possible relationships that can occur and be implemented between the two concepts. The framework designed in the paper focuses on self-service provided by banks by utilizing the development of one of the technologies from industry 4.0, namely the Internet of Things. The merging of Industry 4.0 and Banking 4.0 will later create an Integrated Customer Centric Ecosystem that implements several services such as Smart Home with Smart Procurement, Smart Wearables with smart Authentication for banking, Smart Banking Customer Services Using Virtual Assistant and Secure Banking with Smart Contracts.


In "The Separation of Powers, Court Curbing, and Judicial Legitimacy" (American Journal of Political Science 53 (4): 971-89 (2009)), there is a slight error in the proof of Proposition 3. Specifically, Congress's (C 's) payoff from deviating to a pure strategy, !(! = L ) = h should be given by (1 − m)bc − mbc − e. C 's strategy from playing a pure strategy !(! = L ) = l is given by e − bc . Thus, the mixing probability that makes C indifferent between playing!(! = H) = l and!(! = H) = h is m = bc−e bc . This probability holds for all bc > e. Thus, the equilibrium characterized in Proposition 3 exists for all bc > e. Note that this correction does not affect the substantive interpretation of the model or the empirical implications derived. In the article, analysis was constrained to the case where bc 2e, it was asserted there exists a pooling equilibrium in which the Court never makes a constrained decision upon observing Court curbing. The comparative static derived was that as bc increases—as the Court and Congress become more ideologically divergent—the Court should be less likely to make a constrained decision upon observing Court curbing. The algebraic correction reveals that the semi separating equilibrium holds for all b > e, and the restriction that bc < 2e is not necessary. However, the probability with which the Court makes an unconstrained decision upon observing Court curbing (! = h), m = bc−e bc , is increasing in bc . Thus, the prediction that judicial restraint in response to Court curbing should decrease as Congress becomes more ideologically divergent from the Court continues to hold.


Synthetic bone has become an important tool for education in the orthopaedics field and biomechanical research. The use of the conventional tool such as cadaver has become a challenge to the researcher and orthopaedic surgeon, as it was highly cost, ethical issues and storage. In addition, the available synthetic bones in the market were expensive and only in European size. This research was focusing on developing the synthetic bone using polyurethane material, evaluate the mechanical strength of the developed synthetic bone and characterize the morphological structure of the developed synthetic bone. The development of the synthetic bone was using Polyurethane (PU) as its material. Two type composition of PU was used for this research. The material mixed and poured into the mould that has been designed according to American Society Testing and Material (ASTM) standard which was ASTM-F1839. Then, composition 1 and composition 2 undergo mechanical testing and morphology analysis by using Instron and Scanning Electron Microscopy (SEM) respectively. The average Young's Modulus of composition 1 and composition 2 were 208.6963 MPa and 384.6304 MPa respectively. In short, the developed synthetic bone has greater Young's modulus compared to the synthetic bone that available in the market and which are 132.3254 MPa (Sawbone) and 68.1483 MPa (Synbone). The morphological analysis has shown the fabricated synthetic bone has compact structure compare to the one in the market that mimic the cancellous bone. In conclusion, composition 2 of PU have the highest Young's modulus but from the morphological analysis it does not mimic the morphology of cancellous bone.


We reexamine the evolution of idiosyncratic volatility (IV) of US firms between 1962 and 2016, and its relation to expected returns. The unusually high variance of new firmly listed stocks from 1962 to 1997 materializes in a trend in the IV and, contrary to the conclusions of related studies, in systemic risk. A decreasing market concentration attenuates the trend in the latter before 1997. The subsequent reversal of IV stems from the bias in correlations before 1997 due to measurement errors among existing illiquid stocks. Young and distressed stocks are crucial for obtaining the negative IV-expected return relation.


The study object was medicinal herb Pyrola rotundifolia leaf. To identify biologically active substances in medicinal plants, they used the thin-layer chromatography (TLC). TLC studies used a chromatographic plate Silica Gel 60 F254 (Mersk, Germany), a chromatographic chamber CAMAG, a samples applicator Linomat 5 (CAMAG, Switzerland), a UV lamp to view chromatograms CAMAG, and standard examples of flavonoids and phenolcarbonic acids (Sigma-Aldrich). Accurately weighed quantities of standard identification samples were dissolved in appropriate volumes of methanol and rutin to quantify in ethanol (70% (v / v)). For quantitative determination of flavonoids, they used the differential spectrophotometry method with a spectrophotometer Cary-50. Content of flavonoids was converted in rutin. Applying modern approaches to standardization of medicinal plants, they processed methods of identification and quantification of flavonoids in Pyrola rotundifolia leaf. An identification criterion to be incorporated into the quality control technique applicable to medicinal plants is TLC determined flavonoids. They substantiated and experimentally proved that a quantitative indicator of Pyrola rotundifolia leaf is flavonoid content, a quantitative criterion of which still to be determined through analysis of more samples. Based on modern approaches to standardization of herbal medicines, they have processed methods for identification and quantification of flavonoids in medicinal plants – Pyrola rotundifolia leaf. They offered incorporating the TLC-based flavonoids identification method into the quality control procedures applicable to Pyrola rotundifolia leaf; identification markers shall be availability of four flavonoids, including hyperoside and luteolin-7-O-glucoside, and three phenol-glycosides, which may be arbutin derivatives. Methods to control quality of medical plant shall include quantitative determination of flavonoids by the spectrofluorimetric method. However, to establish quantitative criterion, further research is required using more samples of Pyrola rotundifolia leaf from different vegetation regions.


POTENT preparations of interferon obtained from the brains of mice infected with West Nile virus (Finter, 1964a, 1965), can be used to protect other mice against large doses of Semliki Forest virus (SFV) injected into the peritoneum. This system can be used as a model to explore the potentialities of interferon as an agent for the prophylaxis and therapy of a virus infection in vivo. Some pre-liminary results have been reported elsewhere (Finter, 1964b). wide range. injections NDV


We present a new implementation of the polarizable continuum model (PCM) at the multiconfigurational self-consistent field (MCSCF) level. This new MCSCF-PCM implementation is based on a second-order algorithm for the optimization of the wave function of the solvated molecule. The robust convergence properties of this approach allows for fast convergence of the PCM-MCSCF wave function for large MCSCF expansions as well as for excited states of solvated molecules. Our implementation also enables us to treat nonequilibrium solvation—that is, to treat excited molecular states generated in a fast excitation process such that not all degrees of freedom of the solvent have relaxed. To demonstrate the applicability of the approach we present calculations of solvation effects on 1,3-dipolar systems and on the ground and excited states of methylenecyclopropene.


The security aspect represents a major challenge for the intelligent transport system, whether it is securing the system's various components such as the network and communication between the various nodes or securing the nodes themselves. In ITS, data is generated at high speed, and the data shared between the nodes of the network changes over time at a very high speed. Securing the data shared by the nodes is essential to ensure the integrity and reliable communication. In this paper, we will propose a methodology to detect packets' behavior sent between the different nodes using a data stream clustering algorithm since the data shared between the nodes verify the data stream criteria.


We investigated the motion of the Earth's artificial satellite Interball-1 by using a method suitable for the computation of large eccentricity orbits. Though the measured and the computed orbital elements differ from each other within the measured error bound, we found a slight tendency for secular decreasing in the semi-major axis, caused probably by electromagnetic drag. We analysed the dominant role of the Moon in the variations of the orbital eccentricity, leading to zero perigee height and the end of the lifetime of the satellite. (© 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)


The advent of Active Antenna Systems has provided new ways and features for increasing the capacity of mobile networks in order to cope with the ever increasing traffic demand. One such feature is the vertical sectorisation (VS) technique where a cell is divided into an inner and an outer sector by using a second downtilted beam from one antenna. The two sectors use the same spectrum resources but share the electrical power available. The limitation in available power per sector, raises the question whether there is gain in using VS, and if so, how much and under which circumstances. This paper presents some new numerical results on the performance gains of VS in a realistic LTE network environment, especially for the case of independent activation of the feature across cells in the network. We also present a framework for the design of a SON controller enabling the smart (de)activation of the feature based on the estimated/observed traffic distribution. The controller design follows two steps: first the functional form of the controller is derived based on analytical modelling, and then this functional form is calibrated using realistic measurements in a statistical learning fashion.


Background: Aggregation of mutant huntingtin into inclusion bodies is a pathogenic feature of Huntington disease. Results: Genetic and pharmacological activation of the heat shock stress response (HSR) promotes inclusion body formation. Conclusion: Activation of the HSR contributes to mutant huntingtin aggregation. Significance: HSR activation as a therapeutic strategy may promote rather than suppress aggregation of proteins implicated in neurodegenerative disease. The cellular heat shock response (HSR) protects cells from toxicity associated with defective protein folding, and this pathway is widely viewed as a potential pharmacological target to treat neurodegenerative diseases linked to protein aggregation. Here we show that the HSR is not activated by mutant huntingtin (HTT) even in cells selected for the highest expression levels and for the presence of inclusion bodies containing aggregated protein. Surprisingly, HSR activation by HSF1 overexpression or by administration of a small molecule activator lowers the concentration threshold at which HTT forms inclusion bodies in cells expressing aggregation-prone, polyglutamine-expanded fragments of HTT. These data suggest that the HSR does not mitigate inclusion body formation.


The timely detection and appropriate identification of causal agents associated with disease of crop plants or seeds are considered to be the most important issue in formulating the management strategies for plant diseases. This is particularly important for plant diseases of a fungal nature, where disease-free planting materials is the only effective way to restrict the disease . Beside this, morphological discrimination requires special skill and the expertise of taxonomists or specialists and also time consuming. To simplify the detection, end-point polymerase chain reaction (PCR) assays were developed. Consensus sequences obtained from multiple alignments of target genes, RAPD based methodology was used to design the SCAR maker for rapid detection of P. infestans (amplified product 524bp). BLASTn was also used for in silico specificity. No cross reactivity was observed when primers were checked against other Phytophthora spp. The described primer sets allowed accurate identification and detection of P. infestans . All tests have multiple applications including screening of healthy planting materials, breeding programs and disease diagnosis.


Ayurveda is one among the oldest health science. Nowadays due to faulty life style, dietpattern mental stress and strain healthy status of human being is in declining. Due tochanging life style, there is tremendous increase in disorder related to mahasrotas(gastrointestinal tract). Amlapitta is a major disease of mahasrotas. Amlapitta is pittapredominance disease which is realated to Annavaha srotas &Purishvaha Srotas occurs dueto mandagni and ama. When Amla guna of pitta is increased is called Amlapitta. Variousacharyas has explained amlapitta as separate disorders but Samprapti of Amlapitta is clearlymentioned in Grahani chikitsadhyay while describing samprapti of Grahani Dosha. The basicprincipleoftreatment are mainly nidanaparivarjana, shodhana, and shamanachikitsa. Vamana and Virechana are mentioned for urdhva gati and adho gati of doshas. In modern science it can b ecorrelated with Gastritis.


Research in integrated passive components is becoming more widespread, as the advantages of increased reliability, reduced cost and improved performance are recognised. The subject of this paper is the integration of inductor components in MCM-L technology for RF applications. A detailed analysis of the sensitivity of an RF amplifier to components of parasitic impedance associated with MCM-L integrated inductors is presented. SPICE circuit models are used for this purpose. The performance of a range of integrated test devices is compared with specifications for equivalent commercial devices. Inductance values ranging from 4.5-27.4 nH are produced, with Q-values of up to 100. Such performance is shown to be perfectly suited for the application of integrated inductors in RF amplifier circuits.


ABSTRAK The study aims to test the direct and indirect effects of earnings management on earnings persistence through different tax books. Opportunistic earnings management results can reduced persistence of accruals. A decrease in accrual persistence will reduce earnings persistence. Different book tax variable were added as an alternative explanation. Earnings management can increase the book tax different reported by the company. A high tax different book can also reduce earnings persistence. A high tax different book is a signal of poor earnings quality. The population of this study is companies listed on the Indonesia Stock Exchange. The sample of this research is manufacturing companies listed on the Indonesia Stock Exchange Data analysis methods used in this study were descriptive statistics and path analysis. The path analysis results prove that there is the indirect effect of earnings management on earnings persistence through different tax books. The results of the study prove that there is no the direct influence of earnings management on earnings persistence. E-JA e-Jurnal Akuntansi e-ISSN 2302-8556


Women nurture. This has been the expectation, experience, the timeless lore and historic fact of our lives. Not until this century have we started to ask the meaning and cost of this age-old assumption. Throughout history, women bonded together as they did traditional "women's work". They wove understanding, consolation, and support even humor through communal cooking and sewing and childcare. Today, however, many women do "men's work, their jobs and careers are often based on male role models and, in the process they've become more and more isolated from each other. Even stay-at-home moms are experiencing this sense of isolation (Biziou, 2009). This paper attempts to describe three communities namely Hindus, Muslims and Santals in Birbhum West Bengal and exhibits how ritual domain is a part and parcel of women's life in India. It throws light on the women world in ritualistic performances in rites of passage and ceremonies organized by the communities. The study focuses on life-cycle rituals of these communities on one hand and points out that each one of them has a great bearing in the life of an individual. On the other hand, it concentrates on ritual ceremonies performed in the villages and the way these festivals inculcate a sense of belongingness and solidarity.


This experiment using corn as raw materials,produced unique health flavor yellow wine with the whole liquid.The processing of this wine is liquefied by α-amylase and mashed by root molds and black molds.During this processing adding 0.2% acidic wine with proteinase can raise yellow wine flavor.When purebred alcohol fermenting at the whole liquid state,ventilation foster at 30℃ in the early days and airtight foster at 28℃ in the later days can improve fermentation speed infectively.Aging with high or low temperature interval at the hermetic stage can reduce the period of aging.This technology have share promotion intention to the whole liquid state processing of rice wine.


The analysis and study of the features of the spread of the COVID-19 coronavirus pandemic in European countries are performed. The study is based on the territorial unevenness of the localization of the disease, the increased walking and driving mobility of people, the decreased level of social discipline of the population of different countries and other factors. The regularities of the cyclical occurrence of pandemics of infectious diseases were studied using the cases of swine flu, Ebola and COVID-19 (which occurred over the past 12 years) and their impact on the development of the world economy and global society. The negative consequences of the impact of the COVID-19 pandemic on the global economy and international business are analyzed.


No survey of clinically important immunological phenomena would be complete without consideration of the functions of phagocytic cells. They play a pivotal role in the immune response by kiling microbes, by presenting antigens to lymphocytes and by serving as supportive, accessory cells to lymphocytes, at least partly by releasing soluble factors. The phagocytes of the body, professional and non professional, consist of two specialized groups of cells: granulocytes, which can be mobilized rapidly and which reach inflamed sites quickly and in large numbers, and which are highly efficient at dealing with many types of injury and infection but which have no capacity for differentiation and live only a short time; and the mononuclear phagocyte system consisting partly of motile cells which respond initially more slowly than neutrophils but which can differentiate in sites of inflammation into cells which are more efficient in various functions than the cells from which they originated. Many mononuclear phagocytes are fixed cells located in tissues where they act as trays or filters for material circulating through the tissue. Phagocytes, which usually function as the primary defender in infections, have also been implicated as effector cells in several conditions characterized by a destructive inflammatory response.


The advancement of Internet of Medical Things (IoMT) leading to the proliferation of electronic healthcare scenarios, with an expanding trend of hospitals and healthcare organizations employing Electronic Medical Records (EMRs) with uploading to the cloud for sharing. However, security challenges exist during the generation and uploading of medical records, such as record tampering, key attacks, etc., which will become the maximum bottleneck restricting the development of e-Health scenarios in the near future. Some scholars consider digital signature techniques, such as Attribute-based Signature, to address the security challenges but ignoring its overwhelming efficiency. In this paper, we propose a lightweight forward secure aggregate signature for e-Health scenarios. We devise a lightweight secure aggregate signature to provide unforgeability and forward security for medical records, which is the first aggregate signature scheme that enables forward security in e-Health scenarios. Furthermore, our scheme offers superior lightweight properties, requiring only 5.78ms for aggregation and 4.85ms for verification of 1000 signatures, which is significantly lower than existing schemes, especially suitable for medical systems with enormous data volume. Security analysis and experimental evaluation indicate that our scheme assures correctness, unforgeability and forward security, while fulfilling lightweight demands that outperform existing schemes.


The objective of this article is to present a panorama of the journalistic coverage of science and technology themes in Latin America, taking as a case study 12 newspapers of signifcant impact in the region, involving nine countries. We collected the stories published in the science section from January to April 2006, and analyzed them based on the constructed week methodology and using quantitative tools. In total, our sample amounted to 681 stories. Among our fndings, we observed an important presence of medicine and health issues as main topics of the stories. National science has space in the newspapers, although less than scientifc results from developed countries. Benefts are stressed in the stories, while a low level of controversies is observed. Scientists are the main source for the journalists, with a low representation of the former in stereotyped images in most of the newspapers.


Background: Currently, Acinetobacter baumannii is considered the leading cause of nosocomial infections with an alarming and increasing level of antibiotic resistance. Objectives: to determine the prevalence of carbapenem resistance and the presence of OXA-51, OXA-23, IMP genes encoding carbapenemase of bacteria Acinetobacter baumannii at Can Tho City General Hospital. Materials and methods: A cross-sectional descriptive study with analysis on 135 samples of Acinetobacter baumannii bacteria isolated from respiratory specimens at Can Tho City General Hospital in 2021-2022. Results:The overall carbapenem resistance prevalence of Acinetobacter baumannii was high, 88.1%. In which, the prevalence of resistance to meropenem was 93.3%, ertapenem was 90.4% and imipenem was 86.7%. Up to 94.1% of Acinetobacter baumannii samples had the presence of the OXA-51 gene, the OXA-23 gene was 89.6% and the lowest was the presence of the IMP gene with 14.1%. Conclusion:The carbapenem resistance rate of Acinetobacter baumannii was quite high,


MEMBERS of the TGF-β family have been described to bind to a heteromeric complex of two types of serine/threonine kinase receptors, named TβR-I and TβR-II. These receptor molecules are essential for TGF-β-specific signalling. Several type I and type II receptors have been identified by a variety of methods. TGF-β 2 and 3 are widely expressed in the CNS and exert multiple functions on neurones and glia. Although the TβR-I molecule is abundant in the CNS, it was unclear whether the type II receptor found in peripheral organs is also expressed in the CNS. Previous, negative findings, seemed to suggest that a novel, as yet undescribed type II receptor may be expressed in the CNS. We used competitive RT-PCR to detect TβR-II mRNA in rats at different stages of development (E18, P6, adult) and in different tissues. We detected this mRNA in the lung, liver, heart, gut, kidney, and pituitary of adult rats. Surprisingly, and in contrast to previous studies, similar levels of the TβR-II mRNA were also detected in several regions of the CNS, namely cortex, midbrain, cerebellum, brain stem and hippocampus. We therefore tentatively conclude that TGF-β2 and 3 may signal in the brain by means of the same type-I and -II receptors as found in peripheral organs.


The process of Mg-cored wire feeding was investigated. The Mg cored wire with special structure was applied in inclusion modification in steel. The process of feeding the Mg-cored wire is more smoothly than feeding the Mg-wire with old structure in steel treating at 1600°C, the absorption ratio is higher and more stable than that of the old process. After being treated by Mg-cored wire feeding, the Al2O3 inclusions with the big size changes to the fine particles of MgO?Al2O3 inclusions. At same time, the Al2O3?MnS inclusions changes to the Al2O3?MgS?MnS inclusions.


In the recent years several studies on population ageing in the most advanced countries argued that the share of people older than 65 years is steadily increasing. In order to tackle this phenomena, a significant effort has been devoted to the development of advanced technologies for supervising the domestic environments and their inhabitants to provide them assistance in their own home. In this context, the present paper aims to delineate a novel, highly-integrated system for advanced analysis of human behaviours. It is based on the fusion of the audio and vision frameworks, developed at the Multimedia Assistive Technology Laboratory (MATeLab) of the Università Politecnica delle Marche, in order to operate in the ambient assisted living context exploiting audio-visual domain features. The existing video framework exploits vertical RGB-D sensors for people tracking, interaction analysis and users activities detection in domestic scenarios. The depth information has been used to remove the affect of the appearance variation and to evaluate users activities inside the home and in front of the fixtures. In addition, group interactions are monitored and analysed. On the other side, the audio framework recognises voice commands by continuously monitoring the acoustic home environment. In addition, a hands-free communication to a relative or to a healthcare centre is automatically triggered when a distress call is detected. Echo and interference cancellation algorithms guarantee the high-quality communication and reliable speech recognition, respectively. The system we intend to delineate, thus, exploits multi-domain information, gathered from audio and video frameworks each, and stores them in a remote cloud for instant processing and analysis of the scene. Related actions are consequently performed.


Introduction. In the field of implementation of integrated programs of housing construction as a promising direction from the point of view of solution of the most important problems of modern development of the construction industry (intensive growth of urban areas, low quality and high cost of new housing, poor infrastructure), the key task has been set: rationale of the characteristics of the complex of construction sites taking into account interrelations between the number and characteristics of residential buildings and infrastructure facilities. Based on the results of the analysis of the relevant scientific literature, the conclusion was made that the existing tools are limited and fully take into account the key features of the implementation of integrated programs of housing construction. Relevance of research which objective is development of a method of substantiation of characteristics of a complex of construction sites is substantiated.
Materials and methods. The organizational and process characteristics method of the complex of construction sites on the basis of linear fractional programming, which implies the determination of the optimal number of housing construction sites and infrastructure facilities in the context of different instances and categories by the criterion of maximizing the profitability index of the corresponding construction project was developed. The key elements of the developed method are optimization models, which are linear relatively unknown variables and therefore implemented using simplex method in modern software environments of optimization modeling.
Results. The developed method is implemented on a practical example using Microsoft Excel software environment and the "Solution Finder" add-in. As a result of performance of corresponding calculation procedures, concrete values of quantity of sites and infrastructure facilities within the limits of the building project have been received.
Conclusions. On the basis of adequate results obtained from the implementation of the proposed methodology on practical example, the conclusion was made about the high practical significance of the developed tool. The main shortcomings of the developed method are revealed, connected with the absence of consideration of factors of influence of features of a transport infrastructure and technological resources within the limits of construction procedure on characteristics of the project. In order to eliminate the identified shortcomings, it is planned to improve the methodology at further stages of the research.


Elastic parameters of pavement materials, used in modern methods of design of flexible pavements, are commonly inferred from results of tests which follow different procedures for different materials, eg Marshall test for bituminous surfacings and California bearing ratio test for other materials. Neither of these tests measures the behaviour of the material in flexure. In addition, parameters thus obtained are then assumed constant for each material, irrespective of changing conditions of compaction, moisture content and temperature. Using the Hveem cohesiometer, all materials which possess some cohesion or cementing action are tested in flexure, in an identical way and hence their characteristics are measured directly and in the same units. Because each material can be so tested over a range of conditions, it is to be hoped that this type of test will provide a more reliable indication of the service performance of pavement component layers than standard tests currently in use (a). The number of the covering abstract of the conference is TRIS No. 368448. (TRRL)


In order to meet the performance test requirements of high-voltage capacitors for production enterprises,orderly to improve the acceptance rate and production technology of the capacitors,the authors developed the main control circuit for the qualification test and voltage test of high-voltage storage capacitors and designed a multi-functional test platform.The designed system can work well under complex environments.It takes FPGA as digital control platform,and takes state machine to implement logic control.Each kind of capacitors in different condition,i.e.,different volts,different frequency,different discharge current,etc.,can be tested on the platform through changing the parameters.The test platform has been put into use in the factory.It works well and has high stability and reliability.The practical results indicate that the platform can meet the test requirements of production enterprises.


microRNAs(miRNAs)are evolutionary conserved small noncoding RNAs of 18 to 25nt that were found in all metazoans,and it regulates gene expression by base pairing with their target mRNA,leading to mRNA cleavage or translational repression.let-7is a small RNA molecule originally found in worms,and it is highly conserved and plays a vital role in posttranscriptional regulation.The study found that let-7takes part in the development of organs and tissues.This review summarized the recent progresses about the function of let-7miRNA in the development of brain,nervous system,lung and cardiovascular system,and muscle development,and elucidated the possible mechanism of regulating the developmental processes of animal tissues and organs.It will provide the basis for further exploring the function of let-7miRNA in animals.


Mosquitoes Culex sp. is the main vector of filariasis. Population control using chemical larvicides continuously can cause resistance. The leaves of the pletekan plant (Ruellia tuberosa L.) and lime fruit (Citrus aurantifolia) have the potential as natural larvicides. This study aims to determine the differences in high toxicity (LC50) of pletekan leaf extract and lime fruit on the mortality of Culex sp. mosquito larvae with an exposure time of 24 hours. Pletekan leaf extract and lime fruit were extracted by maceration using 97% ethanol. The LC50 can use probit analysis with SPSS applications. The results showed that pletekan leaves were toxic to Culex sp. mosquito larvae with an LC50 value of 710.169 ppm with the lowest concentration of 615.231 ppm and the highest concentration of 796.157 ppm. The LC50 value of lime fruit extract was 1026.749 ppm, with a lower limit of 846.406 ppm and an upper limit of 1294.531 ppm.


SUMMARY Processing of wood with bark adds some ten per cent to the pulp yield of the log but by eliminating expensive debarking, may increase the economically available product of the stand by 100 per cent and more. Resource estimates based on conventional inventories thus understate the true potential to an extent that demands early re-appraisal.


In this paper, we prove the following Theorem. Let F(x) be an irreducible integral valued polynomial of degree k without any fixed prime divisor. Let π(N; F(x)) denote the number of primes represented by F(x) as x = 1, 2, …, N. Then where ω(m) = h_m(k!m)/k! and h_m(k!m) denotes the number of solutions of the congruence F(x) ≡0(mcd m) (0 ≤x k!m). This result is slightly better than the result due to Heilbroun and Ricci. In the proof, the Selberg's method is used. Similar problems of reducible F(x) has also been considered.


Background: The main problem in nitrogen fertilization for crop cultivated is the very low efficiency due to the leaching process. The purpose of this study was to the determination of the optimum levels of biochar amendment made from Melaleuca cajuputi biochar (MCB) and urea fertilizer (UF) for nitrogen use efficiency in upland rice under M. cajuputi stands.Methods: The study was conducted during dry season within March to June 2019 in Menggoran Forest Resort, Playen Forest Section, Yogyakarta Forest Management District, Indonesia. The experimental design was laid out in a randomized complete block design factorial with three replications as the response surface methodology (RSM). The treatments consisted of MCB levels (0, 5, 10, 15 tons ha-1) and UF levels (0, 100, 200, 300 kg ha-1) as independent variables. The observation parameters were nitrate reductase activity (NRA), total chlorophyll (TC), leaf photosynthesis rate (LPR), nitrogen loss (NL), nitrogen use efficiency (NUE) and seed yield (SY). The data was analyzed using RSM approach and ridge regression.Result: The optimizing applications of 11.14 tons ha-1 of MCB and 281.13 kg ha-1 of UF resulted in NUE and SY by 2.14 kg grain kg Nfertilizer-1 and 5.83 tons ha-1 or increased by 19.07% and 13.02%, compared to a single application of UF by 300 kg ha-1.


AN IGNITION SYSTEM FOR INTERNAL COMBUSTION ENGINE WITH AN IGNITION SPARKS UNDERSTANDS an ignition coil, a spark plug CONNECTED TO secondary winding, A SUPPLY CIRCUIT ASSOCIATED WITH WINDING PRIMARY COIL, the said CIRCUIT DEVICE SEMICONDUCTOR CONTROLLED an electronic control unit being programmed to generate a loading cycle during which the instantaneous current flowing through the primary winding gRADUALLY INCREASE OF A MINIMUM VALUE TO A MAXIMUM VALUE AND tHEN THE MINIMUM VALUE snap back. THE electronic control unit is programmed to generate an SUCCESSION FOR CHARGING CYCLES CYCLE ENGINE AND THE SAME. EACH OF SUCH CHARGING PHASES OF PREVIOUS CYCLE IS SEPARATED BY A time interval (W) lasting either equal or greater than the duration (DA) A discharge cycle.


In this paper we are trying to prove the existence of a U shape relationship between some of bank specific variables that can affect on liquidity risk and profitability ratios (ROE, ROA). The point is running such an issue is to evaluate the effectiveness of these bank specific variables on banks profitability in both short and long run. In order to fulfill this mission, variable's data are gathered for the period of 2005 to 2011, and then using generalized method of moments (GMM), the relationship between bank profitability ratios and independent variables are estimated. Our results prove existence of a U shape relation between the above mentioned variables.


In order to coordinate the many design parameters of the solid rocket motor (SRM) grain to get a better performance. A structure optimization method based on variation sketch and genetic optimization algorithm is proposed. Then by choosing a slotted-tube grain as the example, corresponding structure parameters optimization processes show the efficiency and convenience of this advanced structure optimization method. The objective function of SRM internal ballistics curves are converged after about 500 generations' evolution. The SRM internal ballistics curves comparison with initial one and optimized one also shows that the fluctuation range of the internal ballistics curve is reduced from about 20% to 8%. This is helpful to reduce the negative weight of SRM and improve its performance. It proves the accuracy of this grain design and optimization method.


The world senior population is projected to douDle as a percentage over the whole population in the next decades. In order to preserve or improve the quality of life of this population, as well as to keep healthcare costs sustainable, it is important to better support their ability of independent living. Cognitive decline is a major threat to independent living; it may be experienced in normal aging but it may also lead to mild cognitive impairment (MCI) and more serious neurodegenerative cognitive disorders. Early detection of cognitive decline, accurate diagnosis and monitoring of its evolution for early intervention are a priority. Researchers have found that subtle differences in performing instrumental activities of daily living (IADLs) as well as the recognition of subtle errors while performing IADLs may be useful for MCI diagnosis as well as to differentiate different forms of cognitive disorders. However, occasionally performing ability tests in equipped rooms on medical premises has several shortcomings including cost and reliability of results. Pervasive computing coupled with intelligent data analysis can have a major role in this application domain by continuous monitoring of activities at home during daily life. This idea has been at the core of several recent research projects. The main challenges that we are facing are: a) reliability, unobtrusiveness and affordability of the sensor infrastructure, b) precision and robustness of techniques for IADL recognition, c) effectiveness of algorithms for recognizing fine-grained abnormal behaviors identified by clinicians as relevant indicators, d) identification of relevant patterns through long-term data analysis, e) privacy-awareness of data acquisition and management, f) effectiveness of visualization and interaction tools for clinicians. This talk will discuss the above challenges, report the experience on using hybrid statistical and knowledge-based techniques for addressing the recognition tasks, and identify critical aspects still to be investigated.


Belgium Agreement relating to the Canada Pension Plan, Ottawa, April 2, 1968; in force April 2, 1968, terminated December 31, 1986. Agreement on Air Transport (with Memorandum of Understanding), Brussels, May 13, 1986; in force May 13, 1986. Brazil Long Term Wheat Agreement, Brasilia, October 10, 1985; in force October 10, 1985, with effect from January i, 1986. Agreement on Air Transport, Brasilia, May 15, 1986; in force provisionally May 15, 1986.


This study aims to describe the improvement of procedure text writing in class XI MIPA 1 Yogyakarta State Senior High School 6 using the Problem Based Learning (PBL) demonstration method. The method of this research is classroom action research. The research subjects were XI MIPA 1 Yogyakarta State Senior High School totaling 35 students. This study consisted of two cycles. Data collection techniques used were observation, interview, procedure text writing test, and documentation. Data analysis using qualitative and quantitative descriptive analysis techniques. Validity of data with validity (democratic, process, dialogic) and triangulation. The results showed that the demonstration method of Problem Based Learning can improve the ability to write procedural texts in terms of processes and results in class XI MIPA 1 Yogyakarta 6 Senior High School Improving the quality of the process can be seen from the role of teachers and students who experienced a significant increase in the implementation of learning. This is indicated by the emergence of a positive response through the attitude of cooperation and enthusiasm shown by students, as well as conducive conditions of learning. Process improvement ultimately has a positive impact on increasing yield. The increase in results can be seen from the increase in the score of the procedure text of students from the first cycle to the second cycle. The average score at the time of the action was 68.14 on average in the first cycle of 68.57, and the average in the second cycle was 80.64. The increase in the average score from pre-action to cycle II is 12.05.


This article discusses some functional conditions criterion of Sign Language Translators- Interpreters (TILS), that act in the process of deaf student education enrolled in brazilian schools at the regular education system. We undertake discussions on aspects such as functional linking and wages, trying to see how these subjects feel themselves in their places, and how they are affected by it in their daily lives. Grounded on the enunciation-discourse theory of Mikhail Bakhtin, this study utilized employed face-to-face interviews as a main base on data construction, and in addition, one profile with training data, bonding and professional experience. Also taking notes of contextual elements, were relevant to the subjects' understanding and their speeches. Altogether 27 TILS participated from thirteen municipalities among eight Brazilian states. As results, it was outstanding that TILs are not just about nomenclatures and functional linking. Such developments, may affect the performance expectations and linked social representations. The data also demonstrate a diverse social movement to meet the existing education and inclusion public policies, depending on each specific situation, may compromise, greatly, how these TILS are seen and their integration-participation in the institutional as a whole.


Civil litigation contract,which is established by equal parties,refers to the agreement in order to make procedural effects directly or indirectly.The rationality of civil litigation contract is multiple.It involves the analysis of main role,the autonomy principle and the inner justice in civil procedure.


In recent years, the personal deposits of our country have been showing a tendency of growing fast all the time, and the huge resident savings formed the banking "black hole", which influenced monetary policy conducting and sound development of macroeconomy seriously. So, the question of personal deposits distributary becomes the urgent task facing us. Unloosening management limit, quickening business amalgamation, strengthening innovation, breaking system obstacles, and advancing the development of the securities which substituted saving actively can be regarded as the important measure distributing the huge personal deposits effectively and packing the banking "black hole".


The Author, of Astilleros Espanoles S.A. (AESA), reviews the design and equipment of roll-on/roll-off ships, with particular reference to his company's designs, under the headings: A. History. Ro/Ro Ships in the North Sea--Intercontinental Ro/Ro Ships. B. Design Philosophy of the Roll-On/Roll-Off Ship. C. Development of AEAS's Ro/Ro Designs. Range of Tonnage Covered--Hull Forms--Hull Structure and Deck Loadings--Free Height between Decks--Double Hull--Ramps and Lifts--Vehicle Ways, Layout of containers, and Lashings--Engine-Room Layout--Fire-Protection Systems--Stability and Loading Conditons--Ro/Ro Prototypes Developed by ASEA. D. Ro/Lo Ships. Principal particulars and general-arrangement drawings are included (under Section C) of designs developed by AESA for six twin-screw roll-on/roll-off ships covering a deadweight range from 9,000 to 30,000 tonnes, together with engine-room plans for a 12,000-dwt ship in this range. Section D gives a brief description, with general-arrangement drawings of a design for a 16,000-dwt roll-on/roll-off ship-type developed by the company and named the "Roloflex".


Experiments in our laboratory have arrived at squeezing in a pulse-excited fiber ring. The pulse excitation suppresses stimulated Brillouin scattering, and at the low frequencies used for the measurement, which are made possible by the pump separation, guided acoustic-wave Brillouin scattering is ineffective. It is likely that large squeezing can be realized by using solitons in the same fiber-ring configuration, because solitons assure better squeezing phase profiles. These findings encouraged us to "design" a fiber gyro that performs below the standard quantum limit. It consists of two fiber-ring reflectors; the first acts as a squeezer, and the second acts as a Sagnac interferometer. We use the theory of quantization of solitons.1 The pulse injected into the first fiber ring is a sech adjusted so as to travel as a pair of countertraveling solitons in the squeezing ring.2 The ring acts like a Mach-Zehnder interferometer folded back on itself. The pump is reflected from the pump port, and the vacuum port has squeezed vacuum emerging from it. The pump is recycled in the second Sagnac ring to act as the signal for the rotation sensing. The squeezed vacuum from the first ring is injected into the vacuum port of the Sagnac interferometer. Because practical design considerations dictate fiber lengths on the order of 100 m for both rings, the nonlinearity in the Sagnac ring cannot be neglected. It produces its own squeezing but in the wrong phase for detector noise reduction. However, by proper adjustment of the squeezing in both interferometers, it is possible to counteract the harmful squeezing effect in the Sagnac interferometer and still arrive at a net reduction of the detector noise.


The first objective of this paper is to do seismic interpretation of thirty four 3D seismic sections for identifying the structural traps, and the second is to use the well log data to determine the reservoir characteristics and fluid contents. The seismic interpretation covered eight steps, namely; reflectors identification, picking and correlation of reflectors, fault location, closing loops, velocity analysis, digitization, time to depth conversion, constructing geo-seismic cross-sections and construction of the isochronous and structural contour maps. The seismic interpretation reflects the outstanding role of faulting and folding on the top of Bahariya Formation in the studied area. The high values of core porosity indicate that the Bahariya Formation belongs to the high quality reservoir. The low correlation coefficients of some porosity relations reflect the influence of porosity heterogeneity in the studied wells. The well log analysis procedures are performed in five phases; Digitizing, data gathering, environmental corrections, multi-well normalization and formation evaluation tasks. The well log interpretation used to determine the properties and fluid contents of Bahariya reservoir indicates its high values of porosity, that consider it as a high quality reservoir. The fluid contents of Bahariya Formation are illustrated in three forms; distribution maps, litho-saturation cross-plots and


Objective: To analyze the relationship between the social aspects of university students and the knowledge about the transmission of Sexually Transmitted Infections. Method: A cross-sectional descriptive study carried out at a university. The participants were university students aged 18 to 29 and with active enrollment. The stratified uniform sample was adopted by sex, making a total of 384 male students and 384 female students. The instrument of data collection used was a questionnaire. Data were analyzed using Software Statistical Package for the Social Sciences. Results: Young university students had knowledge below-average regarding Sexually Transmitted Infections, as for association with social aspects, female students, married or living together, who had children and attended the health area, had more knowledge, being statistically significant (p=<0.05). Conclusion: It is necessary to improve the health education strategies of the young university population.


Injuries and degenerative disease of the skeletal and articular systems are the most common reasons for undergoing orthopaedic surgery. Those diseases are often associated with pain, which is experienced by the patient long before the surgical procedure. Strong stress reaction is the main source of adjustment disorders of patients undergoing surgical treatment. Orthopaedic surgery, like any other surgery, upsets body's homeostasis. The results of the surgery are not completely predictable, but are always closely related to life and health. Patients' strong stress reaction is also connected with anaesthesia (emergence from anaesthesia), being worried of complications caused by central neuraxial anaesthesia – the fear of paresis or death. The factor which influences worse adaptation process is the patients' post-surgery mood. Right after the surgery, patients feel worse than before it, they are weak, move less freely, they are anxious about their consciousness being dimmed due to medicine intake and pain. The expectations concerning the ways of controlling the dynamics of the pain one experiences are crucial. According to the researchers, in the central nervous system there exist neural circuits that may cause physiological reactions according to one's expectations, and due to this fact the pain one experiences may become stronger or alleviated depending on one's expectations. The lack of positive pain-reducing experience may lead to the learned helplessness or no sense of one's control over pain, both of which make the pain stronger. The pain-influencing factors include cognitive processes and emotions. The role of attention processes, one's cognitive appraisal and one's attitude towards pain has been emphasised, as well as the pain-modelling influence of emotions, all of which emphasise the complexity of one's pain experience. Patients, when asked to point out the factors that hinder effective pain therapy, indicate frustration caused by the lack of information, numerous worries concerning the treatment and the stereotypical image of pain. Relieving tension influences the patient's mood positively, whilst stress influences it in a negative way. The stress one experiences and one's emotions lower one's pain threshold, which leads to greater pain experience and thus makes the healing process last longer. The quality of pre- and post-operational care is thus crucial, as it influences the level of the experienced stress. The pain components influence one another, there occur interactions of biological, psychological and situational factors, which makes it advisable to personalise one's pain treatment. The need of an interdisciplinary approach towards a person, especially to their health, has been recently emphasised. Pain is a biopsychosocial occurrence, which makes pain therapy an interdisciplinary problem. This chapter discusses the following issues: 1) The characteristics of pain in conditions that require surgical treatment,2) Surgery-related stress reaction, 3) Psychological factors which influence how one feels pain, 4) The consequences of pain in people's functioning, and 5) Postoperative pain, the assessment of pain level and its relieving.


In workflow management systems(WFMSs),appropriate consideration of applying scheduling techniques to manage actors' personal worklists is essential for successful implementation of workflow technology.Mainly,the attention of existing workflow scheduling has focused on the process perspective.As a result,issues associated with personal worklist's perspective,i.e.,worklists that contain actors' to-do activity instances,have been largely neglected.Given this motivation,this paper for the first time,investigates issues in personal worklist scheduling under dynamic workflow environment.Towards these issues,the paper proposes a novel genetic algorithm to optimize the personal worklist management.This algorithm recommends for each actor a feasible worklist that will ensure the worklist's activity instances' successful execution while minimizing the total overtime costs for all personal worklists.Through comparing with other well-known workflow scheduling algorithms,the paper evaluates the effectiveness of the proposed genetic algorithm with a specific example and a simulation experiment.


The Hawara Pyramid is an outstanding monument. However, the mudbrick structure shows signs of erosion, and the passages and chambers are currently submerged. The problem of water ingress has mainly arisen since the 1880s. In this study, an initial assessment of the pyramid structure was made and causes of water ingress were investigated through analysis of water samples. Stable oxygen isotope measurements indicate that the source of water within the pyramid is the Bahr Selah canal. Water within the pyramid is highly saline compared to the Bahr Selah, and evaporation can only partly account for this high salinity. The composition of dissolved ions suggests that dissolution of salts in soils and from bedrock in the vicinity of the pyramid has enhanced the salinity of water percolating into the pyramid structure. Water ingress and salt deposition are at present the main threat to the integrity of the monument. © 2007 Wiley Periodicals, Inc.


It is stated that the positive impact of «Biostim» is expres-sed in an increase of protective powers of the chicken organism because of the protein amount increase.


Objective To observe and contrast the biochemical features of the diploid Paragonimus westermani in different geographic districts. Methods The P. westermani adults came from two regions, Hunan and Jiangxi Province of China. The concentration gradient polyacrylamide gel slab electrophoresis(CGPAGSE) and America BioRed Gel Doc 2000 Quantity one gel image analysis system were used to detect and analyze the esterase(EST), malate dehydrogenase(MDH), lactate dehydrogenase(LDH), alkaline phosphatase(ALP) and general progeins(PT) of P. westermani. Results The fluke EST of P. westermani from two regions was almost identity. The band number and relative mobility of the MDH and LDH were close to identical, though the protein content and the grade of bands had some differences. Some discriminations were detected in band number and relative mobility of ALP, and the more differences were inspected in it's protein content and grade band also. The band number, ralative mobility and band grade of fluke's PT were alike except for the protein content, which has obvious differences. Conclusion The patterns of isoenzymes and proteins of diploid P. westermani in Hunan and Jiangxi show polymorphism. It is possible that both intratype differentiation develop and there are different biological types in diploid.


An apparatus for transporting sheets or folded products by means of a conveyor belt which has at least one retaining element for the sheet or folded product, while the existing of a resilient bi-metallic holding member is a gripper tongue (6, 14) directly (under prestress with the conveyor belt 2) or (with a gripper bar 13) cooperates, which is arranged between two mutually parallel conveyor belts (12), said gripper tongue (6, 14) (by means of a heat source 17) can be actuated.


Abstract : This toxicology study was conducted to provide toxicity data relevant to the exposure in rats to test atmospheres of pyrotechnically disseminated M18 red smoke. Acute nose-only inhalation exposure to an average atmospheric concentration of 1.92 mg/L red smoke for 30 minutes did not induce mortality in male and female rats. Subacute (2-week) nose-only inhalation exposure to average atmospheric concentrations of 0, 0.1, 0.5, and 1.5 mg/L red smoke for 30 minutes/day did not result in any mortality or significant clinical signs at any exposure level. Test article-related histopathological findings were primarily observed in the anterior regions of the nose in male and female rats at all exposure levels. Increased incidence of nasal mucosal degeneration was identified as the critical endpoint in this study and was used to derive BMDL10 of 0.351 and 0.054 mg/L for male and female rats, respectively. Red smoke-induced histopathological findings at the 1.5 mg/L exposure level exhibited a regression of injury following a 4-week recovery period.


Summary The distribution of antibody to Nairobi sheep disease in sheep and goats in Kenya was found to coincide closely with that of the tick, Rhipicephalus appendiculatus. The proportions of a population in an enzootic area with antibody was similar in the different age groups. No antibody to the virus was found in rodent sera and while some low titres were found in some wild ruminant sera, these were considered to be most likely cross reactions with antibody to related viruses.


Nebraska and Pennsylvania currently have laws in place that prohibit public school teachers from wearing religious garb. This Note applies the appropriate constitutional framework––a balancing test––in order to determine the propriety of a religious garb statute. Courts have upheld the statutes in light of perceived government endorsement of teachers' religion and feared impact on impressionable young children. However, both of these concerns are exaggerated and misplaced. Rather, a court must consider the demands a newly globalized world places on effective education for tomorrow's global citizens.


Many harmonics components are contained within the stator currents of the high-speed synchronous reluctance motor, SynRM, with salient pole rotor They cause the power factor of SynRM to get worse
In this paper, the mathematical model of SynRM is investigated, and SV_PWM control method is applied to reduce harmonics components in the stator current
Simulation results show the fast response of speed and the reduction of harmonics components at steady state.


Let $p\ge5$ be a prime and $T$ a Kodaira type of the special fiber of an elliptic curve. We estimate the number of elliptic curves over $\mathbb Q$ up to height $X$ with Kodaira type $T$ at $p$. This enables us find the proportion of elliptic curves over $\mathbb Q$, when ordered by height, with Kodaira type $T$ at a prime $p\ge5$ inside the set of all elliptic curves. This proportion is a rational function in $p$. For instance, we show that $\displaystyle\frac{p^8(p-1)}{p^9-1}$ of all elliptic curves with bad reduction at $p$ are of multiplicative reduction. Furthermore, we prove that the prime-to-$6$ part of the conductors of a majority ($=\zeta(10)/\zeta(2)\approx 0.6$) of elliptic curves are squarefree, where $\zeta$ is the Riemann-zeta function.


Probabilistic modelling methods are increasingly being em-ployed in engineering applications. These approaches make inferences about the distribution for output quantities of interest. A challenge in applying probabilistic computer models (simulators) is validating output distributions against samples from observational data. An ideal validation metric is one that intuitively provides information on key differences between the simulator output and observational distributions, such as statistical distances/divergences. Within the literature only a small set of statistical distances/divergences have been utilised for this task; often selected based on user experience and without reference to the wider variety avail-able. As a result, this paper offers a unifying framework of statistical distances/divergences, categorising those implemented within the literature, providing a greater understanding of their benefits, and offering new potential measures as validation metrics. In this paper two families of measures for quantifying differences between distributions, that encompass the existing statistical distances/divergences within the literature, are analysed: f-divergence and Integral Probability Metrics (IPMs). Specific measures from these families are highlighted, providing an assessment of current and new validation metrics, with a discussion of their merits in determining simulator adequacy, offering validation metrics with greater sensitivity in quantifying differences across the range of probability mass.


We propose a method to control a small self-propelled aircraft using limited control surfaces. We further propose the use of a differential flatness based control to a follow a time-varying trajectory. We demonstrate in simulation the ability to track a planned trajectory using this method.


Reconstruction of scalp defects is challenging. Theuse of Leukocyteand platelet-rich fibrin (L-PRF) in closing scalp defects has not yet been described in the literature. The use of L-PRF is well known in dentoalveolar surgery: LPRF enhances periodontal healing and may contribute to bony regeneration in maxillary sinus floor augmentation and dental implant osseointegration. Leukocyte-rich and platelet-rich fibrin has also been shown to induce blood vessel formation in vivo. Several medical disciplines have seen the benefits of LPRF for wound healing; it is being used for dura closure in neurosurgery and in the treatment of refractory leg ulcers.


Cd1−xMnxTe (CMT) is a wide bandgap semiconductor that stands out among the ternary compounds in several industrial applications, such as optoelectronic and solar cell devices. Therefore, it is worth understanding the mechanisms of light interaction with CMT produced by growth techniques. In this work, we investigate the room temperature Raman scattering by longitudinal optical phonon modes CdTe-like (LO1) and MnTe-like (LO2) in CMT thin films grown on Si(111) by molecular-beam epitaxy. The well-known linear dependence of LO1 and LO2 frequencies on x is observed in Raman spectra when the excitation photon energy is above the bandgap energy. As expected, for the excitation energy of the incident laser line near the fundamental gap of CMT, the resonance becomes evident in the Raman results. However, for a specific resonance condition due to tuning of the bandgap energy dependence on Mn concentration, the frequencies of the LO1 and LO2 phonon modes remain constant as the average manganese concentration increases to values x≳ 0.30. From micro-photoluminescence spectroscopy investigations, we concluded that for Mn concentration above 0.3, a broad range of optical transitions provides the required conditions for a resonant Raman scattering selected by the incident photon energy. It introduces a resonant selectivity of regions where the incident excitation energy coincides with a bandgap energy associated with a specific value of x, even for samples with nominally different compositions. The results show the sensitivity of resonant Raman to express diagnostics of ternary compound growth.


This study presents the modelling and simulation of a single area powersystem network containing three different generating sources, solar thermalpower plant (STPP), thermal, and diesel power plants. The simultaneousfrequency and voltage control problem has been investigated using LinearQuadratic Regulator (LQR) and State Feedback based Sliding Mode Control(SF-SMC) design. Also, the integration of Particle Swarm Optimization(PSO) has been considered for the selection of LQR cost function weightmatrices and SMC control parameters. Proper selection of LQR and SF-SMCparameters allows the controllers to handle the complexities involved in avery efficient manner and also augments necessary robustness in the con-troller design. The transient performance of the PSO based LQR and SF-SMCcontrolled system has been assessed in terms of time-domain performanceindices, and it has been compared with the conventional PID and 2-DOF PIDcontrollers. Additionally, the robustness of the proposed controllers has beentested and verified after contemplating variation in model parameters


Objective:To investigate the relationship between adiponectin and insulin resistance in polycystic ovary syndrome(PCOS).Methods:Forty-two patients with PCOS(non-obese PCOS group,26;obese PCOS group,16) and 28 normal women(non-obese control group,19;obese control group,9) were enrolled.LH,FSH,T,insulin,glucose,adiponectin level were measured.Results:LH,LH/FSH and T in PCOS patients were all significant higher than those in control groups.Compared with the non-obese control group,in other three groups adiponectin was decreased significantly,while HOMA-IR were significantly higher.Adiponectin level was negatively related with BMI,HOMA-IR and T.Conclusion:It is suggested that a diponectin may be insufficient in PCOS,related with insulin resistance.Adipon ectin will have a promising future as a kind of novel medicine.


The 'Russian Livonia' project was an attempt to establish a province of Russian Tsardom in the lands conquered in Livonia between 1558–1560 which could be regarded as a model of integration of foreign territories into Russia in the 16th century. Russian authorities used a number of integration approaches, such as the system of agreements with Livonian cities and later the political model of the Holy Roman Empire. They tried to found a Livonian Kingdom, which was subordinate to Ivan the Terrible as Emperor. There were two attempts to carry out this reform: in 1564 and in 1569–1578, both unsuccessful. They never led to the integration of Livonia into the Russian state and commonwealth. The Russification of Livonia failed. Livonia saved its status as a middle earth between different cultures.


Spectral optoacoustic imaging uses two or more optical wavelengths for the excitation of ultrasonic waves in order to obtain spectrally resolved images of tissue. We developed a wavelength-multiplexing method that enables the simultaneous generation and detection of optoacoustic waves with two optical wavelengths emitted from a pump laser - optical parametric oscillator system. Two-dimensional images were taken with a linearly scanning optoacoustic transducer from phantoms and from tissue in vivo. The time required for signal acquisition depended solely on the pulse repetition rate of the laser. At presence, with a 10 Hz system, this time was between 10 and 20 seconds. Pairs of images at two wavelengths show an exact overlap of the imaged structures. Wavelength-dependent variations of optical absorption coefficients are visualized by calculating ratio and difference images. The presented experimental results demonstrate the feasibility of the method to generate maps of blood oxygenation.


Abstract We prove that the steady state Navier–Stokes equations have a solution in an exterior Lipschitz domain of , vanishing at infinity, provided the boundary datum belongs to .


The aim of this study was to research the assessment of a reasonable standard of living in relation to a holistic view regarding the right of care in a nursing home. Our selection of empirical material was 6 judgements from Swedish courts and 16 social inquiry from local authorities of social work. The material was limited to dismissal of the right of care in a nursing home, within the years of 2016 to 2019. An analysis of judgements was initial in our study, where we used Lupita Svenssons method for non-solicitors to analyse the judgments connection to the intention of the law of social services. The results of the analysis became access to the qualitative text analysis of the social inquiries, with a perspective of salutogenic administration and discretion. The main result of this study was that the courts' assessments are based on a precedent from the supreme administrative court, that emphasizes the intention of the law of a holistic view. The results also showed that the local authorities rarely make a holistic assessment and that local guidelines limit the care administrators discretion. Which jeopardize that the assessments are not in accordance with the intention of the law of social services. (Less)