A path linking kidney function, endothelial dysfunction and heart failure with preserved ejection fraction (HFpEF) can be found in this issue.1–3 The review by ter Maaten et al. sets the stage.4 It shows how renal impairment can cause inflammatory activation and endothelial dysfunction leading to myocardial stiffening, hypertrophy and fibrosis.4 Then, Rammos et al. show how a dietary supplementation of inorganic nitrates can reverse age-dependent abnormalities in left ventricular (LV) diastolic function in wild-type mice5 pointing out, again, the central role of nitric oxide deficit as a cause of diastolic dysfunction in aging and heart failure (HF).5 With respect to biomarkers, Emmens et al. evaluated plasma kidney injury molecule-1 (KIM-1), a marker of tubular damage, in 2033 patients with acute HF. KIM-1 was associated with glomerular filtration rate and urinary NGAL and was an independent predictor of 60-day HF rehospitalizations but not mortality.6 The connection between the kidney and HFpEF is further explored by Patel et al. who assessed renal denervation therapy (RDT) in 25 patients with HFpEF in a single-centre, randomized, open-controlled study.7 The study was terminated early and was therefore underpowered to reach significant results. Although no changes in the prespecified endpoints were found with renal denervation compared with optimal medical treatment, more patients had an improvement in peak VO2 and E/e' in the intervention group.7 Further studies are needed to assess the effects of RDT in patients with HF.8 Other highlights of this issue regard the epidemiology of HF. The results of the ESC-HF-Long-Term Registry are now available. It includes 12 440 patients recruited between May 2011 and April 2013 in 211 cardiology centres from 21 European and/or Mediterranean countries. It shows a relatively low one-year mortality rate of 6.4% for outpatients with a still high mortality rate of 23.6% for patients hospitalized for acute HF. In addition, one-year mortality and HF hospitalization rates remain high in both outpatients and patients with acute HF (14.5% and 36%, respectively). Geographical differences are also shown.9 Prognosis of patients with Takotsubo syndrome is still a matter of debate. Long-term all-cause mortality is shown as relatively high, actually higher than in patients admitted for ST-elevation myocardial infarction, in one study in this issue.10 The role of non-adherence to treatment is shown as an important independent .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. risk factor for major outcomes in the patients enrolled in the Systolic Heart failure treatment with the If -inhibitor ivabradine Trial (SHIFT).11


Purpose The ability to predict cash demand is crucial for the operation of construction companies. Reliable cash flow prediction during the execution phase can help managers to avoid cash shortages and to control project cash flow effectively. Method This paper presents a new inference model, CF-ELSIMT, for cash flow forecasting. The developed CF-ELSIMT utilizes weighted Least Squares Support Vector Machine (wLSSVM) as a supervised learning technique to generalize the mapping function between input and output of cash flow time series. A novel dynamic time function (TF) is employed to determine the weighting values associated with data in different time periods. The dynamic TF allows the model to deal with distinct characteristics in cash flow time series. To optimize the model's tuning parameters, the new inference model incorporates Differential Evolution (DE) as the search engine. In addition, a machine-learning-based interval estimation (MLIE) approach is used to arrive at the prediction interval of forecasted cash demand. Results & Discussion The CFELSIMT provides construction planners with a point estimate coupled with the lower and upper prediction intervals. Experimental results and comparisons have demonstrated that the newly established model has enhanced the forecasting accuracy.


In this thesis, I examine the extent to which the media censorship of the Pinochet dictatorship, which ended over 20 years ago, continues to influence Chilean public opinion and policy today. The dictatorship's control, penetration and censorship of the press in the 1970s and 1980s appears to have created a lack of pluralism in the media that helped the dictatorship retain political power for 17 years. However, it seems that the dictatorship's influence did not end with its reign and that this lack of media pluralism still exists today and could be correlated with a widespread conservatism in Chilean public opinion. After providing a brief history of Chile and the dictatorship's immediate impact on the media, I present a qualitative analysis that compares El Mercurio, a conservative and prominent Chilean newspaper, and La Nación, a newspaper that historically has served as the government mouthpiece, to determine if both the 1973 and present press have conservative tendencies that could impact readers. To discover if the findings are unique to Chile, I compare the results to those of the Argentine press and indicate that Argentina has more media pluralism and less widespread conservatism than Chile, regardless of the two nation's similarities. Lastly, to determine if the dictatorship's censorship has had a tangible impact on Chilean public opinion today, I quantitatively analyze media framing bias through cross-tabulations of Chilean ideology and trends in news consumption. Based on the comparative content analysis of Chilean newspapers both during and after the dictatorship, the juxtaposition of these findings to trends in Argentine media, and the quantitative analysis of the relationship between Chilean media and trends in public opinion, I conclude that, while the dictatorship's censorship still influences content in the press today, there are other factors that may be more significant in influencing Chilean public opinion and policy.


Cardiorenal syndrome (CRS) can be defined as a clinicalpathological disorder in which a primary insult in the kidney or heart initiates a series of functional and morphological secondary dysfunctions with responses in the other organs [1]. Subtype 1 (acute CRS) is characterized by rapid worsening of cardiac function leading to acute kidney injury (AKI) [2]. The definition of acute kidney injury (KDIGO-2012) is based on three criteria: increased serum creatinine higher or equal to 0.3 mgdl within 48 h or increased serum creatinine higher or equalto 1.5 times the baseline value, occurring in the last 7 days or debit less than 0.5mlkgh for more than 6h. Although a relatively common syndrome, treatment of a cardiorenal syndrome requires particularities, such as optimization of cardiac output with inotropic drugs, continuous intravenous use of diuretics, combination of diuretics, and sometimes ultrafiltration. Therefore, the presence of the cardiorenal syndrome is the translation of a more serious clinical situation, requiring an individualized therapy regarding the risk that each patient presents for the development of renal dysfunction and careful to avoid worsening of the clinical condition in the short term. Whenever possible you should choose drugs that help preserve kidney function [3] The objective of the study was to report a case of CRS type 1, originating from a cardiogenic shock that resulted in AKI and to show the importance of the early treatment for the positive outcome of the case. Case Report


Background: The National Rural Health Mission has introduced village-level female community health worker, accredited social health activist (ASHA) who acts as an interface between the community and the public health system. The is study was conducted to assess the awareness and perceptions of ASHA regarding their roles and responsibilities in health-care system and factors affecting their performance in delivering health-care services. Methodology: A qualitative study was conducted in seven selected villages under Talegaon Primary Health Centers, Wardha district, Maharashtra, which is also field practice area of a medical college. Nonprobability sampling (purposive sampling) was done. In-depth interviews were conducted on ASHAs (n = 7) of those selected villages till saturation of data. Data were analyzed using the thematic framework approach. Results: ASHAs perception regarding their job responsibilities appeared to be incomplete. They had good awareness regarding their roles and responsibilities as a link worker. They were found to be mostly interested in higher incentive performances. ASHAs clarity regarding their roles and responsibilities as facilitator, social activist, and service provider was found to be somewhat compromised. They were ignorant about their roles and responsibilities under various newly launched national programs. The positive factors influencing ASHAs performances were regular supervision of their performances and appraisal by higher authority and support from community, family, and good relations with coworkers and staff. Challenges faced by most of the ASHAs were more workload, poor orientation to program, lack of quality training, and inadequate and delayed monetary incentives. Conclusion: Good quality training with regular refresher training sessions and regularization of incentives are required to motivate them ASHAs.


Present investigation deals with the comparison of performance of a Generalized Impedance Controller (GIC) based 3-phase self excited induction generator (SEIG) terminal voltage and frequency regulator, having single and two-loop control, in an isolated wind/microhydro type renewable energy conversion system (RECS). Where, GIC is a PWM voltage source converter with dc-bus battery, having controlled four-quadrant equivalent impedance. Amplitude and frequency regulation of SEIG terminal voltage under source and load perturbations, are accomplished by controlling modulation index m of the GIC and phase angle δ of fundamental component of GIC terminal voltage with respect to SEIG terminal voltage. These m and δ control are achieved by operating the GIC in closed loop with, (i) only voltage feedback, and (ii) voltage and frequency feedbacks. The PI-controllers in both the schemes are designed for non-fragile system operation with optimized transient response of both amplitude and frequency of SEIG terminal voltage. The integrated SEIG-GIC closed loop system with single and two-loop control schemes are modeled and simulated in MATLAB/Simulink to highlight the superior performance of single-loop control scheme in transient and steady states.


The New South Wales (NSW) government is looking to redesign the state's bushfire management policy and strategy after facing severe fire for the past few years. A mixture of hazard reduction burning and logging techniques are proposed as mitigations to the bushfire problem in New South Wales; subsequently, we were asked to find the optimal combination of the two to combat fire spread. We approached the problem by first designing a cellular automaton model of forest fires with age-dependent parameters for tree growth influence and undergrowth influence. We examined within-model formulations of HRB and logging by performing Shotgun Hill optimization to determine optimal HRB and logging locations, and found HRB most effective at reducing cumulative burned sites.


In temperate climates, seedlings and saplings have often been assumed to be more sensitive to late‐spring freezes than conspecific adult trees. Yet, no data are available to compare the freezing resistance of juvenile and adult trees at their phenologically most sensitive stage, that is, during leaf‐out. Emerging leaves of seedlings, saplings and adult trees were collected in spring 2013 in seven temperate tree species in a mature mixed forest in the foothills of the Swiss Jura Mountains. Freezing resistance of these emerging leaves was assessed using different target temperatures (−13 to +4 °C) in seven computer‐controlled freezers. Additionally, we assessed the risk that species encounter freeze damages based on temperature data recorded since 1898. The different study species showed contrasting freezing resistance, with the LT50 (median lethal freezing temperature) of emerging leaves ranging from −3.5 ± 0.2 °C (Fraxinus excelsior) to −8.3 ± 0.2 °C (Prunus avium). Within species, juvenile trees (seedlings or saplings) were found to be as sensitive to freezing temperatures as mature trees when the same developmental stage of foliage was compared. Based on phenological observations made during spring 2012, long time series of temperatures indicate a very low risk of freeze damage at the study site, especially for adult trees. Synthesis. We conclude that seedlings and saplings are more prone to freeze damage than adult trees because of their earlier flushing rather than due to a higher sensitivity to freezing as such. Our study highlights that the timing of spring phenology has evolved in such a way that it minimizes the risk of freeze damage according to the species‐specific LT50. Early flushing species are among the most freezing‐resistant species during flushing, whereas late flushing species are among the least resistant. We conclude that for the examined species the species‐specific freezing resistance during leaf emergence could be extracted from either adult or juvenile trees, as long as it is estimated at a same phenological stage.


The oscillation of droplets supported by solid surfaces is important for a wide variety of applications such as dropwise condensation. In the present study, the axisymmetric natural oscillations of a liquid drop supported by a flat surface are investigated by direct numerical simulation. The liquid–gas interface is captured using a geometric volume-of-fluid method. A parametric study is carried out by varying the equilibrium contact angle and the gravitational Bond number (Bo). Both positive and negative gravities are considered, and thus the results cover both pendant and sessile drops. To incorporate the effect of contact line mobility, the two asymptotic limits, namely, the pinned contact line (PCL) and free contact line (FCL) conditions, are considered and their effects on the drop oscillation features are characterized. The predicted oscillation frequencies for PCL and FCL serve as the upper and lower bounds for general situations. The drop oscillation is initiated by increasing the gravity magnitude for a short time. The first mode due to the drop centroid translation dominates the excited oscillation. The oscillation frequency scales with the capillary frequency, and the normalized frequency monotonically decreases with the equilibrium contact angle. For zero gravity, the computed frequencies for all contact angles agree remarkably well with the inviscid theory for both the PCL and FCL conditions. The kinetic energy correction factor is introduced to account for the additional contribution of the oscillation-induced internal flow to the overall kinetic energy of the drop. Both the frequency and the kinetic energy correction factor increase with Bo, decrease with the contact angle, and increase when the contact line condition changed from FCL to PCL. The variation of oscillation frequency due to the change of Bo is particularly significant when the contact angle is large, suggesting that the gravity effect must be incorporated to accurately predict the oscillation frequency for drops supported by hydrophobic or superhydrophobic surfaces.


Because of the many complex subsystem interactions which occur within modern electronic power-processing systems, it is often quite difficult to accurately predict total system performance. A digital computer simulation technique, which can be used to study such composite power-conditioning systems, is applied to a spacecraft direct-energy-transfer power-processing system. The results obtained duplicate actual system performance with considerable accuracy. The validity of the approach and its usefulness in studying various aspects of system performance such as steady-state characteristics and transient responses to severely varying operating conditions are demonstrated experimentally.


Global changes that take place in the external and internal environment are characterized by high dynamism, unpredictability and uncertainty, which is why it is important to solve the problem of improving the innovation management system in e-business. Existing e-business management systems are becoming ineffective, so e-business enterprises are facing a rather difficult period, that is, the stage of attracting innovations. An effective response of the e-business management system, with the involvement of innovations, should play an important role in increasing competitive advantages and maintaining the existing position of the enterprise in the market. Building an effective e-business innovation management system is able to timely adapt the enterprise to changes that occur in the environment of its functioning. A special role in this is played by identifying the factors that can most affect the financial and economic activities of the enterprise in the field of e-business. Successful identification of factors influencing the innovation management system will be the key to sustainable enterprise development. The article analyzes the theoretical material on the classification of factors influencing the innovation management system, as well as identifies the classification criteria by which these factors are determined. According to the conducted research, based on empirical data from e-business enterprises, the factors that have an impact on the innovation management system of an enterprise in the coordinate system of its organizational development have been identified. The identified factors are of practical importance only when they can be used by managers of e-business enterprises when making and implementing innovative decisions. It is proposed to use the method of expert assessments to evaluate these factors for their relative importance. The results obtained, and especially the gradation of these factors by the level of relative importance, are important management information at the stages of making decisions on the management of innovations in e-business enterprises, in particular when choosing management decisions.


The present invention discloses an amino resin reinforcing cellulosic fiber and its preparation method, dry strength fibers ≥2.80cN / dtex, wet strength ≥1.60cN / dtex, wet modulus ≥0.35cN / dtex, the limiting oxygen index of ≥8 %. The method of preparing the amino resin stiffened cellulose fibers, comprising the steps of: a, Preparation of starting material; B, was prepared by blending the step of spinning dope; C, the dope was filtered, defoamed; D, solidified dope forming; E , two bath; F, after the treatment of the fiber. Preparation process of the invention has simple process, the strength and wet modulus fibers made of cellulose fibers than ordinary greatly improved, and there is a certain degree of flame retardancy, good market prospect.


Plant growth condition and plasmid construction Arabidopsis thaliana (L.) Heyhn. (ecotype Columbia-0) plants were grown under long-day conditions (16 h of light and 8 h of darkness) at 22°C on 0.5x Murashige and Skoog (MS) agar plate (Valvekens et al, 1988). The etg1-1 (SALK_071046) and etg1-2 (SALK_145460) alleles were retrieved from the Salk Institute Genomic Analysis Laboratory engine (http://signal.salk.edu/cgi-bin/tdnaexpress) and the seeds were acquired from the Arabidopsis Biological Research Center. To screen for homozygous insertion alleles, the following primer pairs were designed:


Dr Fox's hypothesized explanation (Fox, 1998) for Spiegel et al.'s 1989 finding of prolonged survival among metastatic breast cancer patients receiving supportive/expressive group therapy seems logically implausible. If in fact the 12 control patients surviving longer than 20 months were subject to confounders independently contributing to survival decrements beyond the prognostic factors accounted for by Spiegel et al., what could reasonably explain the fact that they achieved the longest survival AMONG THE CONTROLS?! Would we not expect to see accelerated mortality within such a subgroup? Whether or not ongoing replications validate a survival benefit from this psychosocial intervention, its demonstrated benefits to the quality of life of metastatic breast cancer patients remain undiminished in importance.


The difficulties I have encountered in the radical removal of the tonsil are many and, in order of frequency, may be enumerated thus: Difficulty in removing the whole of the tonsillar mass. Wounding the pillars, which has happened to me twice. Wounding the uvula, which has happened to me once. Difficulty of controlling severe hemorrhage by ligature and tampon, which I have not had to resort to. In several instances I have had to use the tonsillar forceps to control hemorrhage. The cases where the tonsil has not been entirely removed are the ones that have given me trouble from hemorrhage, and I believe the remaining tonsillar tissue is largely responsible for the hemorrhage. By the use of the U-shaped scissors (see illustration) three of these difficulties can be eliminated and the remaining one, that of hemorrhage, very much lessened. However, any one attempting radical removal of the tonsil should


Soft rockfall barriers are complex structures that generally consist of a metallic net supported by steel posts and cables with brake elements. Several experimental and numerical studies have been carried out to evaluate their behaviour and a technical agreement in EU was recently established to certify these barriers based on experimental tests. Actually, manufacturers develop rockfall kits with their own technical specificities. The objective of the present paper is to determine the intrinsic properties of most common nets technologies and to investigate their influence on the overall mechanical behaviour of the structure. To this end, a comprehensive comparison between the local behaviours of the different nets is first presented using equivalent homogeneous membranes. Results derived for square nets under static concentrated loading illustrate the influence of the manufacturing technology on the deflection and stresses distribution. Then, a numerical and analytical model for the so-called "curtain effect" is developed and validated. In the conclusion, it is focused on the capacity of the pro-posed methodology to study and evaluate the response of the whole barrier.


This paper discusses some of the issues that need to be examined to fulfill the promise of Intelligent Transportation Systems (ITS) for African-Americans. By using a human factors approach, it looks at how African-Americans in general, and African-American elderly in particular, may be a risk of becoming marginalized users of ITS unless ITS technologies are made accessible to them.


Since its introduction in 2014, the face morphing forgery (FMF) attack has received significant attention from the biometric and media forensic research communities. The attack aims at creating artificially weakened templates which can be successfully matched against multiple persons. If successful, the attack has an immense impact on many biometric authentication scenarios including the application of electronic machine-readable travel document (eMRTD) at automated border control gates. We extend the StirTrace framework for benchmarking FMF attacks by adding five issues: a novel three-fold definition for the quality of morphed images, a novel FMF realisation (combined morphing), a post-processing operation to simulate the digital image format used in eMRTD (passport scaling 15 kB), an automated face recognition system (VGG face descriptor) as additional means for biometric quality assessment and two feature spaces for FMF detection (keypoint features and fusion of keypoint and Benford features) as additional means for forensic quality assessment. We show that the impact of StirTrace post-processing operations on the biometric quality of morphed face images is negligible except for two noise operators and passport scaling 15 kB, the impact on the forensic quality depends on the type of post-processing, and the new FMF realisation outperforms the previously considered ones.


The loss of the natural posterior teeth is the most common dental problem, especially in the elderly people. The optimal dental management for this condition remains a controversial issue. A treatment plan based on the shortened dental arch concept may be a reasonable alternative, especially in patients with certain restrictions, who cannot be treated as ideal.


To study the effect of double filling of the skutterudite iron antimonides on the thermal conductivity, we have synthesized dense samples of Ca1-xLaxFe4Sb12 (0 les times les 1) and Ca0.3La0.6Fe4-yCoySb12 (y = 1, 1.5) by the spark plasma sintering technique. Electron-probe microanalysis revealed that the double-filled samples with x = 0.25, 0.5, and 0.75 consist of three phases of micrometer scale; CaFe4Sb12, Ca-rich phase, and La-rich phase, respectively. The lattice thermal conductivity at 150 K is smaller by 10-20% than that for the end compounds. This is attributable to the scattering of heat conducting phonons by the local fluctuations in both mass and charge of Ca2+ and La3+ ions. In the full range of x from 0 to 1, the thermopower at 300 K stays at 70 muV/K. This value was increased to 120 muV/K by partial substitution of Co for Fe. The dimensionless figure of merit ZT for Ca0.3La0.6Fe3CoSb12 is estimated to be 0.9 at 800 K, which is comparable to the value reported for p-type Ce0.44Yb0.32Fe3CoSb12.


A method of transmitting data packets in an uplink from a plurality of source user equipments to a base station, the data packets being for onward transmission to a plurality of destination user equipments, is disclosed. The method comprising the steps of determining a measure of a quality of service from the base station to a destination user equipment, and scheduling uplink transmissions from the source user equipments to the base station in dependence on the measure of a quality of service.


In this paper, some potential applications of simulation in structural reliability and availability are presented. Unlike the analytical methods, where assumptions that simplify complex analysis often need to be made, simulation methods can model the structure reliability without simplifying the problem. We propose the use of statistical distributions and techniques –such as survival analysis– to model component-level reliability. Then, using failure- and repair-time distributions and information about the structural logical topology, structural reliability and availability information can be inferred through the use of discrete-event simulation techniques. Two numerical examples illustrate some potential applications of the proposed methodology.


In order to maximize the yield of flavonoids from Cephalanoplos segetam,single factor experiments and response surface methodology(RSM) are employed to optimize the microwave-assisted extraction conditions.The results indicate that the optimum extraction condition are as follows:microwave power 300 W,extraction time 10 min,70% alcohol as solvent,extraction temperature at 70 ℃ and ratio of material to solvent 1∶70(g·mL-1).Under these conditions,the practical yield of flavonoids is 29.95 mg·g-1,which is consistent with the predicted yield of flavonoids of 28.77 mg·g-1.Compared with the traditional solvent extraction techniques,a short application of microwave increase the yield of flavonoids greatly and have shorter extraction time.The microwave-assisted extraction technology of flavonoids from Cephalanoplos segetam is stable and feasible,this shows the obvious advantages and great potential of microwave-assisted extraction of the flavonoids from the plants.


Abstract The matter of bringing about greater uniformity in the rules and regulations of the several egg laying contests being conducted in this country is one to which the writer has given considerable thought. The Poultry Division of the University of California has been actively interested in the three contests in California and the writer formulated the rules for the first contest at Santa Cruz after which the rules for the Petaluma and Pomona contest were patterned. The most serious differences in the rules of our contests are the number of birds per entry, the number kept together in a pen and the use of alternates. The California contests early abandoned the use of alternates because : 1. If the alternates were trapnested as well as the contest flock, the substitution of an alternate and its entire trapnest record for that of the bird it replaced would usually alter the standing . . .


With increasing popularity of portable devices for outdoor activities, portable energy harvesting devices are coming into spot light. The next generation energy harvester which is called hybrid energy harvester can employ more than one mechanism in a single device to optimize portion of the energy that can be harvested from any source of waste energy namely motion, vibration, heat and etc. In spite of few recent attempts for creating hybrid portable devices, the level of output energy still needs to be improved with the intention of employing them in commercial electronic systems or further applications. Moreover, implementing a practical hybrid energy harvester in different application for further investigation is still challenging. This proposal is projected to incorporate a novel approach to maximize and optimize the voltage output of hybrid energy harvesters to achieve a greater conversion efficiency normalized by the total mass of the hybrid device than the simple arithmetic sum of the individual harvesting mechanisms. The energy harvester model previously proposed by Larkin and Tadesse [1] is used as a baseline and a continuous unidirectional rotation is incorporated to maximize and optimize the output. The device harvest mechanical energy from oscillatory motion and convert it to electrical energy through electromagnetic and piezoelectric systems. The new designed mechanism upgrades the device in a way that can harvest energy from both rotational and linear motions by using magnets. Likewise, the piezoelectric section optimized to harvest at least 10% more energy. To the end, the device scaled down for tested with different sources of vibrations in the immediate environment, including machinery operation, bicycle, door motion while opening and closing and finally, human motions. Comparing the results from literature proved that current device has capability to be employed in commercial small electronic devices for enhancement of battery usage or as a backup power source. [1] Larkin, Miles, and Yonas Tadesse. "HM-EH-RT: hybrid multimodal energy harvesting from rotational and translational motions." International Journal of Smart and Nano Materials 4.4 (2013): 257-285.


The creation of large unsightly waste rock dumps is synonymous with mining in much of Western Australia
(WA). In many cases development of the dumps has involved only limited consideration of future closure
requirements and at best has been based on known technologies of the day. The key design focus has
generally been haulage cost. Now, many years later, we are faced with far more stringent decommissioning
requirements and ever increasing public interest in environmental sustainability. To complicate matters,
what in many cases were "ugly, but harmless mountains of mine rubble", now appear to be "contaminant
time bombs". Seepage and runoff from the dumps are often found to have raised concentrations of salts and
metals resulting in potential contamination of what might be considered pristine surface and ground water
environments. The true magnitude of the problem remains unknown, but there is little doubt that at many
mines it represents a potential nightmare for mine closure planners who need to minimise long term
corporate liability.
Too often little, if any, consideration is given to waste rock dump hydrology during mine planning stages
with the result that there is limited knowledge regarding possible seepage/runoff pathways once acid rock
drainage (ARD) occurs. There is little doubt that an adequate understanding of waste rock dump hydrology
is essential in the development of any Source-Pathway-Receptor model. Formulating effective long term
solutions is extremely risky if the pathway component is not fully understood – in this case the inner waste
rock dump hydrological processes.
This paper describes how gaining an insight into waste rock dump hydrology at a mine in northern WA has
greatly enhanced closure planning by highlighting some of the impracticalities of earlier closure strategies.
The paper discusses internal dump structure, hydrological flow paths, discharge hydrographs and water
quality implications.


We derive relations linking the conductivity [sigma][sub *] and elastic moduli of any two-dimensional, isotropic composite material. Specifically, upper and lower bounds are derived on the effective bulk modulus [kappa][sub *] in terms of [sigma][sub *] and on the effective shear modulus [mu][sub *] in terms of [sigma][sub *]. In some cases the bounds are attainable by certain microgeometries and thus optimal. Knowledge of the conductivity can yield sharp estimates of the elastic moduli (and vice versa) even for infinite phase contrast.


The disposable diaper according to the present invention (1) having: a topsheet (2), backsheet (3) and an absorbent body interposed between the longitudinal absorption body (4) is disposed between the two long sheets (5); and a pair of telescoping plate is fixed to the main body along the longitudinal direction of the side edge portions of the absorbent body (6), the telescopic sheet (6) of the outer edge portion of the fastening tape is fixed attachment portion (71) . Stretch panel (6) has a telescopic portion (6B) than the outer edge portion (6A) closer to the lateral direction (Y) is square. The telescopic portion is located ratio (6B) of the stretch panel 6 closer to the lateral direction (Y) of the outer region of the outer edge portion (6A) comprises a constituting member stretch sheet 6 adhered to each other by an adhesive bonded absence cements joint. Inner end with a base end portion (73) (73T) is located over a plurality of elastic members (62) disposed in the body longitudinal direction (X) of the inner most elastic member (62t) closer to the longitudinal direction of the body ( X) outward.


A synthesis of 6,8-dinitro-2,4,6,8-tetraaza[3.3.1]bicyclononan-3-one from dimethyl α,α'-diaminoglutarate was brought about in six steps. A similar conversion of dimethyl α,α'-diaminosuccinate to a derivative of 2,4,6,8-tetraaza[3.3.0]bicyclooctane was unsucessful


The concept of marginality is increasingly used in the field of social policy, albeit often without a great deal of further clarification. It is argued here that the anti-egalitarian tendencies which underpin the welfare ideology of the New Right inevitably lead to an amplification of feelings of stigmatisa tion and exclusion as particular groups become detached from mainstream consumer society. Some of the theoretical dimensions of marginality are outlined, and are examined in the context of recent policy developments which affect one particular social group, namely young people. The publicly stated claims for work experience schemes and board and lodg ings regulations are examined in relation to the evidence of their red ef fects. The evidence indicates that both policies have distinct marginalising tendencies. Finally, it is posited that unless a radical shift takes place in political ideology, the concept of marginalisation is likely to become a per manent fixture in the lexicon of academic social policy.


2553 Background: nab-Paclitaxel is albumin-bound paclitaxel that achieves higher intratumoral concentrations and undergoes receptor-mediated transcytosis across cell membranes. Previous clinical tr...


The presented work provides a way of preserving holography images through rendering the holography images with NeRF and NeRF--, a neural radiance field representation method. This paper explores the feasibility of interpolating photographs of holograms by using the neural radiance field to synthesize novel views. Through quantitative analysis, it demonstrates that the NeRF model is able to interpolate photographs of holograms. ABSTRACT The presented work provides a way of preserving holography images through rendering the holography images with NeRF and NeRF--, a neural radiance field representation method. This paper explores the feasibility of interpolating photographs of holograms by using the neural radiance field to synthesize novel views. To analyze the performance of the view synthesis method, quantitative comparisons between captured hologram images and interpolated views are done with the following metrics: MSE, PSNR, SSIM, and LPIPS. The calculation was done by comparing the ground truth and the interpolated images at a particular view point. The quantitative analysis demonstrates that the NeRF model is able to interpolate photographs of holograms.


Time-resolved extreme ultraviolet spectra of foil-excited 120-MeV Br ions have been recorded, using a spectrometer equipped with a position-sensitive detector. The spectra near \ensuremath{\lambda}=20\char21{}30 nm were measured at times after excitation of up to 6 ns. Prominent in the delayed spectra were the long-lived decays of the intercombination transitions in the Mg-like ${\mathrm{Br}}^{23+}$ and Al-like ${\mathrm{Br}}^{22+}$ ions. The present paper reports on lifetime measurements for intercombination transitions in highly charged bromine ions using such a position-sensitive detector.


This paper is concerned with the neural‐based decentralized adaptive control for interconnected nonlinear systems with prescribed performance and unknown dead zone outputs. In the controller design procedure, neural networks are employed to identify unknown auxiliary functions, and the control design obstacle caused by the output nonlinearity is resolved via introducing Nussbaum function. Then, a reliable neural decentralized adaptive control is developed through incorporating the backstepping method and the prescribed performance technique. In the light of Lyapunov stability theory, it is verified that the proposed control scheme can ensure that all the closed‐loop signals are bounded, and can also guarantee that the tracking errors remain within a small enough compact set with the prescribed performance bounds. Finally, some simulation results are given to illustrate the feasibility of the devised control strategy.


In order to solve the problems in the continuous monitoring rock burst by EMR such as a large amount of the monitoring data,the no-complete analysis of the data,and the no-warning for the danger etc,the continuous monitoring and warning software system of EMR for rock burst was improved according to the characteristics of rock burst and its precursors,which was composed of the data transmission software,the server software and the terminal software.Having the functions of the data storage and the real-time display of the monitoring data,the query of the historical data,the trend analysis and the statistical analysis of the data,the report generation and the warning of the dangers,the software system can be used to real-time monitor and forewarn rock burst by the combination with the critical value method and the dynamic trend method.The application shows that being of visual interface,the easy operation and the stable running,this software system has a wide prospect for the applications of the monitoring and the prediction of rock bust,coal and gas outburst and the observation of the mining pressure.


Based on gravity balance of embankment filling above equivalent area for one pile, conventional HEWLETT's three-dimensional soil-arch analysis method is improved. An analytical solution for pile efficacy is obtained. Influence of pile spacing, pile cap dimension and angle of internal friction of embankment filling on the pile efficacy is analyzed. Pile efficacy calculated by the improved method is less than that obtained by HEWLETT's method.When the soil arch is in plastic state, both methods have the same value. Increasing pile cap dimension is more economy for embankments with large friction angle. Decreasing the pile space is more effective for embankments with small friction angle. Choosing embankment filling with large friction angle is helpful to increasing pile efficacy. Pile efficacy charts are given for engineering application. Finally, these formulas are used to analyze a practical case.


BackgroundRopivacaine is a newly introduced local anesthetic. anesthetic. No data are available regarding its safety, efficacy, or sensory-selectivity in children. The sciatic block duration and systemic toxicity of bupivacaine and ropivacaine were compared compared among infant, adolescent, and adu


Pregnancy is a state of high metabolic demand. Fasting diverts metabolism to fatty acid oxidation, and the fasted response occurs much more rapidly in pregnant women than in the non-pregnant state. The product of the imprinted Delta-like homologue 1 gene (DLK1) is an endocrine signaling molecule that reaches a high concentration in the maternal circulation during late pregnancy. By utilising murine models with deleted Dlk1 we show that the fetus is the source of maternal circulating DLK1. In the absence of fetally-derived DLK1, the maternal fasting response is impaired. Furthermore, we found that maternal circulating DLK1 levels predict embryonic mass in mice and can differentiate healthy small for gestational age (SGA) from pathologically small infants in a human cohort. Therefore measurement of DLK1 in maternal blood may be a valuable method for diagnosing human disorders associated with impaired DLK1 expression, and to predict poor intrauterine growth and complications of pregnancy. Corresponding author firstname.lastname@example.com. Author Contributions M.C., M.A.M.C., A.C.F–S., G.C.S.S. conceived and designed the experiments. M.C., M.A.M.C., J.A.C., M.H., I.G., N.T., C.L.D., D.S.C–J. performed the experiments. M.C., M.A.M.C., A.C.F–S., C.L.D. F.G., G.C.S.S. analysed the data. M.C. U.S. performed statistical analysis. S.R.B., T.L.P., A.C.F–S., G.C.S.S. contributed reagents. M.C., M.A.M.C., A.C.F–S., G.C.S.S. wrote the manuscript. M.C., A.C.F–S., G.C.S.S. provided supervision. Competing financial interests The authors declare no competing financial interests. Europe PMC Funders Group Author Manuscript Nat Genet. Author manuscript; available in PMC 2017 June 01. Published in final edited form as: Nat Genet. 2016 December ; 48(12): 1473–1480. doi:10.1038/ng.3699. E uope PM C Fuders A uhor M ancripts E uope PM C Fuders A uhor M ancripts


In the title compound, C(14)H(23)N(6)O(2)(+) x HSO(4)(-) x H(2)O, the pyrimidinium ring of the cation adopts a twist-boat conformation, induced by steric clashes between adjacent ring substituents; the anions and the water molecules are linked by three O-H.O hydrogen bonds [H...O = 1.70-1.78 A, O...O = 2.548 (2)-2.761 (2) A and O-H...O = 161-168 degrees ] into chains of edge-fused R(4)(4)(12) rings, which are linked into sheets by the cations, via three N-H...O hydrogen bonds [H...O = 1.96-2.17 A, N...O = 2.820 (2)-2.935 (2) A and N-H...O = 145-173 degrees ].


This case report describes a patient with uncontrolled type 2 diabetes mellitus who received steroids for an outpatient infection of COVID-19. The steroid course combined with his acute illness likely contributed to his development of extremely high blood sugar levels (790 mg/dL) and subsequent hyperosmolar hyperglycemic syndrome. In this compromised state, he contracted invasive mucormycosis of the right sinuses and right orbit. This fungal infection caused him to lose his eye and, later, his life. Prescribing systemic steroids comes with many risks. Providers must be careful to use them only when absolutely indicated, especially in patients who are vulnerable to complications, such as those with uncontrolled type 2 diabetes. This case is a grim example of the dangers that can occur with systemic steroid usage.


This is bog situated among agricultural lowlands, in places where deep (>50 cm), wet peat has accumulated to form a gently raised dome. A typical raised bog has three zones: a central extensive, raised and rather level mire expanse, which is surrounded by a rand of deep peat sloping down towards the lagg which is the outermost, lowest zone and has only a thin, patchy peat cover so there is some nutrient enrichment from the underlying mineral soils. The extents of Lowland raised bog are variable from just a few hectares to more than a hundred hectares.


Complacency potential is an important measure to avoid performance error, such as neglecting to detect a system failure. This study updates and expands upon Singh, Molloy, and Parasuraman's 1993 Complacency-Potential Rating Scale (CPRS). We updated and expanded the CPRS questions to include technology commonly used today and how frequently the participants used this technology. The goal of our study was to update the scale and to explore whether there was a relationship between frequency of use and the responses on the updated CPRS measure, based on the original measure's four subscales: confidence-related complacency, reliance-related complacency, trust-related complacency, and safety-related complacency. We hypothesized that 1) higher use would be related with higher complacency scores in each subscale and 2) lower use would be related with lower complacency scores in each subscale. Our research found that there was one frequency of use scale question where the high/low use groups significantly differed in both the confidence-related complacency and trust related complacency subscales.


Effects of nitrogen applied for pot-culturing of Fushu7-6 was studied in the concentration of free proline and soluble protein,membrane permeability,chloroplast ultrastructure in leaves.Six nitrogen dosages were conducted as 0,2.1,4.2,6.3,8.4 and 10.5 g·pot-1,respectively.The data showed that increasing in free proline content,decreasing in soluble protein content and high membrane permeability were resulted by either deficiency or extra nitrogen applied,the phenomenon in swelling of chloroplast and irregular granum thylakoid were observed.The results suggest that proper nitrogen dosage applied to Fushu7-6 is important to keep leaves from the stress of increasing membrane permeability and damaging chloroplast ultrastructure.


Constitutional Statutes seem to describe an oxymoron that challenges the traditional hierarchical dichotomy between regular statutes and constitutional provisions. Constitutional Statutes might mean different things to different political actors (including judges) and academics within the same legal system and across countries. This article argues that we should analyze constitutional statutes along two vectors: what makes these statutes constitutional (identification) and what are the ramifications of such identification (consequences). It further argues that the answer to the first question affects the results of the second. The article argues that statutes are identified as constitutional based on either the process of their enactment or their content, which may itself be subdivided into two classifications: content in terms of importance and content in terms of entrenchment language. Constitutional statutes discussed in the literature and jurisprudence are often treated as though they are made of one cloth, when in fact they belong to different categories based on the justification for, as well as ramifications of, their constitutionality. The article's approach is examined with relation to the U.S., U.K., Canada, Israel, New Zealand and Australia.


[Objective]To investigate HIV,Syphilis and Hepatitis C infections and sexual behavior characteristics among men who have sex with men(MSM)in Hefei.[Methods]By using classified snowball sampling method,the Social mobilization channels included cooperation with MSM Non-governmental organizations,propaganda at gathering area,website and public media.Participants from MSM gathered bars,bathrooms and parks.Under the policy of voluntary and informed consent,anonymous questionnaire,anticoagulant blood collection,HIV,TP and HCV antibody were tested in lab.[Results]395 MSM were investigated during April to July 2008.The average age was 27.6±8.7,73.9% were unmarried.In the past six months,56.7% were homosexual,31.9% were bisexual.The average number of sexual partners was 184.108.40.206% of them were homosexual anal intercourse.45.1% of them used condom in each homosexual anal intercourse.Prevalence rates of HIV,Syphilis and Hepatitis C were 3.0%,13.4% and 1.0%,respectively.Single-factor correlation analysis found the OR of Syphilis infection was 3.408(95%CI=0.989-11.743).No variables were significantly associated with HIV infection.[Conclusion]MSM was the high risk population of HIV,Syphilis and Hepatitis C infection and complex sexual behavior characteristics.The epidemiological surveillance among MSM should be strengthened.


Abstract In this research project, we introduce an interdisciplinary study of language and the law—forensic linguistics. In the field of forensic linguistics, the topic of discourse probably receives the most study. The discourse phenomenon we investigated is interruption, commonly regarded as a display of power and control. Our study concentrated on observing the distributions and functions of interruption that take place in criminal courtroom discourse. Given the unique features in criminal courtroom discourse, such as the highly institutionalized nature, the strong goal orientation, the unique question–answer interaction pattern, its rigid procedure and the high stakes for the defendants, the interruption phenomenon greatly deviates away from that in other settings. For our observation, we collected data from the trial proceedings of criminal courts. The main concern is to determine whether the defendants' right to speak and to be heard is respected by the other participants in the courtroom. Too much interruption may prevent the defendants from explaining themselves, thus infringing on their legal rights. Overall, judges and prosecutors interrupt considerably more frequently than defense lawyers and defendants. The asymmetry in treatment towards the participants in court trials can be censorable. In addition, we found that time pressure prevented judges from giving participants sufficient time to express themselves.


The utility model discloses a valve and a valve core component thereof. The valve has a simple structure, and can be opened and closed with a low torque. The top end of a valve core is provided with a recess; a transmission device is arranged in the recess of the valve core; a radially and inwardly protruding profile is formed in the recess; a radially and outwardly profile is formed for a transmission piece; the transmission piece is provided with an elastic rib; and the elastic rib is separately connected with the inner wall of the recess.


We examine the dividend payment patterns of Korean firms and test competing hypotheses that explain the decreasing dividend patterns since the Asian crisis. We run a horse race to explain this decreasing propensity to pay dividends (PPD). Although catering theory, when used alone, explains 22% of this decreasing PPD, it loses most of its explanatory power when risk and lifecycle measures are used together. We observe dramatic and permanent changes in systematic and idiosyncratic risks after the crisis. Firms are affected heterogeneously, such that large and stable firms face less risk after the shock, while small and unprofitable firms face greater uncertainty, which in turn results in high concentrations of dividend payments among the top payers. We also find evidence of firms' time varying risk aversion toward costly dividend payments. Firms in boom periods become less risk averse and do not reduce dividends for the same perceived level of risks as they do during an economic downturn, when firms tend to react to risks more sensitively. Risks explain over 30% of the decreasing PPD when combined with a lifecycle measure. The added contribution of a lifecycle measure is mainly driven by the sign of retained earnings and not the magnitude of positive retained earnings.


Systematic reviews of relevant controlled experiments are required to set the results of individual studies in proper context, and to assess 'what works' in particular areas of social, psychological or educational intervention. In order to minimise bias, people preparing systematic reviews must identify as high a proportion as possible of the potentially eligible studies, but this phase of data collection is extremely tedious because potentially relevant studies are scattered and often very difficult to locate. This paper describes early progress in creating The Campbell Collaboration Social, Psychological, Educational & Criminological Trials Register (C2-SPECTR) to help those preparing and maintaining systematic reviews in these fields. The register currently contains over 10,000 records, including over 300 references to existing systematic reviews.


Rationale: A prolonged, prodromal phase before definitive paediatric precursor B acute lymphoblastic leukaemia (BCP ALL) diagnosis is rarely observed. Patients concerns: In the first, the patient presented with an aplastic preleukemic phase, whilst the second presented with a rheumatic-like preliminary phase. Diagnoses: The case reports of two patients with BCP ALL with a prodromal phase lasting a few weeks are presented. Interventionsandoutcomes:DNAwhole genomeprofilemethylation analysis of bonemarrowcells obtained at diagnosis revealed a pattern of methylation that was readily distinguishable from both healthy and standard course BCP ALL bone marrow samples. Lessons: The biological implication of this observation remains unclear, with many differentially methylated loci involved in many processes like neurogenesis, cell projection organization and adhesion along with leucocyte activation and apoptosis. The prevalence and clinical significance of these methylation changes is unknown but this data indicates that the epigenetic basis of BCP ALL with a prolonged, prodromal phase requires a more detailed assessment. Abbreviations: ALL = acute lymphoblastic leukemia, BM = bone marrow, CBC = complete blood count, DM = differentially methylated, ESR = erythrocyte sedimentation rate, PLT = platelet count, PP = prodromal phase, SC = standard course, WBC = white blood cells.


Objective To study the feasibility of laparoscopic nerve-sparing radical hystersctomy(LNSRH) technique and its effect on postoperative voiding function.Methods Fifty-two patients with International Federation of Gynecology and Obsterics(FIGO) stage Ⅰb1-Ⅱa1 cervical cancer were divided into study group(LNSRH,n=30) and control group(LRH,n=22),the operating time,operating bleeding and the postoperative recovery of bladder function were compared between the two groups.Results The mean operation time in LNSRH group was(280±42) min,longer than(240±26) min in LNSRH group,respectively,with a significant difference(P0.05).The estimated blood loss in LNSRH Group and LRH group were(180±55) mL and(206±43) mL,respectively,with no significant difference(P0.05).The patients in LNSRH group and LRH group with bladder function recovery normal on day 8 after laparoscopic surgery were 20(66.67%) and 4(18.18%) respectively,with a significant difference(P0.01).The median duration of postoperative catheterization was significantly shorter in LNSRH(10.5±3.8 days) than that in LRH group((25.4±5.5 days)(P0.01).All patients were followed up for 2-20 months with no recurrence and metastasis.Conclusion LNSRH is safe and feasible in effectively alleviating the postoperative dysfunction of the bladder in early cervical cancer as well as in improving the quality of life for patients.


57 patients with constricted abdominal hernia and diagnosed metabolic syndrome were examined. They were performed the urgent hernia defect plastics with polypropylene mesh Linteks-Esfil (St. Petersburg). Patients were divided into two clinical groups: clinical group I (20) included patients in the postoperative period treated with conventional comprehensive conservative treatment. Clinical group II (37) consisted of patients treated with 2.5% solution of 2 ml tiotriazolini in muscle and metformin in a dose of 500 mg / day for metabolic syndrome correction in addition to above mentioned conventional treatment. Lipid metabolism indices improved on the 7th day in 59.2% of patients in clinical group II and only in 15% of patients in clinical group I.Postoperative wound complications such as seromas and infiltrations developed in 6.3% of patients and were eliminated by conservative methods of treatment. Patients of group II tolerated postoperative period better. Average duration of hospital stay decreased by 2.03±0.2 bed days. Thus, the treatment of patients with constricted hernia of anterior abdominal wall and metabolic syndrome should be in complex with hernia defect plastics by propylene mesh and medicamentous correction of metabolism disorders.


The use of isolated hepatocytes as an in-vitro model for toxicity evaluation was discussed. Different hepatocyte-based tests for cytotoxicity measurement were also presented.


The kinetics and products of oxidation of binary Co-5Si alloys in 1 atm of pure O2 at 700 and 800 oC were investigated. Co-5Si alloys followed a parabolic behavior to a good approximation (n=2). The parabolic rate constants as functions of temperature were 2.789×10-11, 2.240×10-10 g2cm-4s-1 at 700 and 800 oC, respectively. The scales formed on Co-5Si alloys were double-layered, with formation of an outer layer of columnar CoO and an inner region containing a mixture of SiO2 and CoO, coupled to the internal oxidation region of Si.


A large portion of the variation in wages and wage growth rates among individuals is due to "unobserved" heterogeneity, and the source of individual heterogeneity is typically attributed to data limitations and/or the unobservability of certain productivity related factors. In this paper we develop a test that discriminates between two inherently unobservable sources of heterogeneity (both of which can clearly account for the variation in wages and wage growth rates): learning ability and workers' inter-temporal preferences (discounting). We apply this test to the large observed differences in wages and wage growth rates between smokers and non-smokers. The evidence supports the discounting hypothesis.


Real-time ultrasound technique, image processing and analysis were applied to develop predition models for interamuscular fat (marbling) in live beef animals in genetic evaluation program. Ultrasound equipment Aloka 500v with a 3.5 Mhz 17 cm linear array transducer was used to do scans for live beef animals. Two scan images were collected on diferrent locations for each animal. The animals were slaughtered within one day after scanning and then a USDA marbling score was recorded and an ether extract (EE) analysis was performed to get a percent fat for each animal. Gray scale histogram, texture and movement analysis were applied to all the scan images. Fourier spectrum statistics variables and movement descriptors were used to develop prediction models. The prediction results demonstrate that the image analysis and real-time ultrasound techniques may be a valuable tool to estimate intramuscular fat for use in sorting feedlot cattle and in genetic evaluation programs for body composition in live beef animals.

Key words: Ultrasonics, Image Analysis, Prediction Models, Genetic Improvement, Live Beef Animals


The global energy sector has been faced with energy scarcity challenges over the past few years. This coupled with environmental concerns due to electricity generation using fossil fuels. This has led to the growth of eco-friendly renewable energy distributed generation (REDG) for electricity generation. In the planning of integrating REDG into the distribution power grid, inappropriate sizing and location of the REDG will result in power system voltage instability, increase in power losses and operational cost increase. It is therefore essential to optimize the location and sizing of REDG for effective performance improvement. In this paper, we propose a genetic algorithm (GA) technique to optimize the size and location of the REDG. The proposed GA technique is validated using the 33 IEEE bus system. From the results obtained it is observed that the active power losses are reduced and the voltage stability of the system is improved


He's a white American student whose ancestors in this country may be traced back at least two centuries. He speaks English, his religion is that of the majority in this country, and his teacher has an ethnic background that closely resembles his own. He should be faring well in American education, but the sociological profile for this student is alarming: one sociologist notes a pervasive fatalistic attitude toward education which means that this student believes his


ABSTRACT The most recent comprehensive estimates of Northern Spotted Owl (Strix occidentalis caurina) natal dispersal distances were reported in 2002. Since then, Northern Spotted Owl populations have experienced substantial demographic changes, with potential attendant changes in natal dispersal distances, including temporal or geographic trends. We analyzed the natal dispersal of Northern Spotted Owls during 1985–2012 in Oregon and Washington, USA (n = 1,534 dispersal events), to determine current natal dispersal distances and to evaluate potential trends that may inform management actions. Mean net dispersal distance (natal site to site of first attempted breeding) was 23.8 km ± 19.2 km SD, with females dispersing ∼50% farther than males. Net dispersal distance varied by ecoregion (Washington Coast and Cascades, Washington Eastern Cascades, Oregon Coast Range, Oregon and California Cascades, and Oregon and California Klamath) but declined similarly in all ecoregions over time (∼1 km yr−1). Dispersal direction also varied by ecoregion, following coarse-scale forest habitat configuration, and was bimodal (north–south) in the Oregon Coast Range, south–southwest in the Oregon and California Cascades, and showed little directionality in the Washington Eastern Cascades, Washington Coast and Cascades, and Oregon and California Klamath. Long-distance dispersal events (>50 km) also varied by ecoregion (mean: 62.3–99.5 km), with most long-distance dispersal (8% of dispersers; distances up to 177 km) originating in southern ecoregions. We found no direct relationship between Barred Owl (Strix varia) detections near natal or settling locations and dispersal distance. These findings, particularly the declining trend of dispersal distances, may inform management actions aimed toward conservation of the Northern Spotted Owl.


This work describes a two-mode clustering hierarchical model capable of dealing with high dimensional data spaces. The algorithm seeks a transformed subspace which can represent the initial data, simplify the problem and possibly lead to a better categorization level. We test the algorithm on two hard classification problems, the phoneme and the pedestrian recognition; both are typical classification problems from real-life applications. Finally, the model is compared with many other algorithms.


Various haemoglobinopathies are major public health problem in Gujarat, a state located in the western part of India. The data pertaining to their occurrence and prevalence in the state of Gujarat are scarce and hence it was considered worthwhile to study the burden of haemoglobinopathies in Gujarat, India. A retrospective analysis of blood samples of 428 cases referred to the pathology laboratory from various private practitioners/Government hospitals for the workup of anemia or other blood related disorders was done by Bio-Rad D-10 instrument. 153 (35.7%) patients out of 428 had haemoglobinopathies. Thalassaemia minor (70 cases, 16.35 %), thalassaemia major (32 cases, 7.48%), sickle cell disease (22 cases, 5.14 %) and sickle cell trait (12 cases, 2.8%) were most common haemoglobinopathies. Less prevalent haemoglobinopathies were sickle-β-thalassaemia, α,βthalassaemia heterozygote, Hb D trait, Hb E trait, Hb Ethalassaemia, Hb D disease, Hb E disease and sickle D disease. Our study indicates that almost all the common haemoglobinopathies are prevalent in Gujarat but sickle cell trait/anemia and β thalassaemia are very common. Various haemoglobinopathies are major public health problem in Gujarat, a state located in the western part of India. The data pertaining to their occurrence and prevalence in the state of Gujarat are scarce and hence it was considered worthwhile to study the burden of haemoglobinopathies in Gujarat, India. A retrospective analysis of blood samples of 428 cases referred to the pathology laboratory from various private practitioners/Government hospitals for the workup of anemia or other blood related disorders was done by BioRad D-10 instrument. 153 (35.7%) patients out of 428 had haemoglobinopathies. Thalassaemia minor (70 cases, 16.35 %), thalassaemia major (32 cases, 7.48%), sickle cell disease (22 cases, 5.14 %) and sickle cell trait (12 cases, 2.8%) were most common haemoglobinopathies. Less prevalent haemoglobinopathies were sickle-?-thalassaemia, ?,?thalassaemia heterozygote, Hb D trait, Hb E trait, Hb Ethalassaemia, Hb D disease, Hb E disease and sickle D disease. Our study indicates that almost all the common haemoglobinopathies are prevalent in Gujarat but sickle cell trait/anemia and ? thalassaemia are very common.


0. The term 'postposition' is employed here to denote a small but important class of simple, complex and compound forms, for the most part translatable by our prepositions. Hickerson interpreted those she met with as suffixes; and this at least some of them most probably are when appended to nouns or to other postpositions. But they also occur quite as often with the personal prefixes (1 sg. dA-, 2 sg. b-, 3 sg. human male 1-, 3 sg. female-neuter th-, 1 pl. oA-, 2 pl. h-, 3 pl. human nA-) and/or suffixes (1 sg. -de, 2 sg. -bo, 3 sg. human male -i, 3 sg. female-neuter -no N -n, 1 pl. -o, 2 pl. -hi, 3 pl. human -ie), which differ somewhat from the corresponding personal pronouns (dai d6i, bii bii, iHi, th6i, oai o6i, hii h6i, nai ' n6i). And if damy is a prefix and -kona thumb a stem in (karika) dak6na my thumb (hurts), there is no linguistically valid reason why dashould be a stem and -khona on; about a suffix in (karika) dakh6na my body (hurts). Moreover, to whatever word-class the postpositions in their morphologically free occurrences may be assigned, they enter as stems into both nouns and verbs; so, from 6ma together with come both th6mathi her male companion and th6makai he is with her.


Radioactive thiabendazole administered orally to farm animals (goats, cattle and swine) as single doses of 50 to 200 mg/kg was rapidly absorbed and metabolized, and effectively excreted. In these animals the only known metabolites are 5-hydroxythiabendazole and its glucuronide or sulfate ester. A spectrophoto-fluorometric procedure for the estimation of these compounds in biological fluids and tissues is presented. The analytical procedure accounted nearly quantitatively for the radioactivity present in the urine.

Peak concentrations in plasma occurred 4 to 7 hours after dosage after which the concentrations decreased rapidly. Approximately 85% of the radioactivity was eliminated in the urine (65%) and feces (20%) in 3 days. No residual thiabendazole or metabolites were detectable in tissue 30 days after administration of 50 mg/kg. Traces of nonthiabendazole radioactivity were barely demonstrable in calves 2 months following doses of 150 and 200 mg/kg.

Small quantities of the drug appeared in the milk of lactating animals. In goats less than 1%, and in dairy cows about 0.1% of the dose was secreted in the milk and peak drug concentrations were found within 24 hours after dosage. Nearly all of the drug was metabolized thiabendazole—only trace quantities of the unchanged compound were present. Thiabendazole and its metabolites were not detectable in the milk 4 days after goats were given a dose of 150 mg/kg or 60 hours after cows were given 220 mg/kg.


In the 1970s, a breeding bird survey was conducted to see how many birds are breeding in Sweden. This was done because the research at the time pointed out that there was a decrease in the number o ...


To the Editor.— This is an affliction long known to man, described frequently in the literature of medicine back to the time of Hippocrates, and much later, Ramazzini. Chaucer makes reference to it in speaking of Weavers Hall, still standing at the very gates of Canterbury. And, of course, the noun itself is in the best Chaucerian Middle English form. Voila—the weavers bottom! When I was a youth, it was considered very daring and provocative to sing— round-fashion—in mixed company about the weavers bottoms! As long as man has sat cross-legged, tailor-fashion, he has placed the weight of his body on the ischiogluteal prominences and the sparse protection of the overlying bursae. Today's generation of youth, much given to the lotus position, has a propensity for squatting on roadsides, curbstones, sidewalks, and floors—almost anywhere. These young people then appear in their "clinics," storefront, drug control, VD, and other out-reach facilities


The problem of defining and working with models of systems that change with time is common to many disciplines. Within artificial intelligence, it is common to provide a computer-based agent with models---or the facility for building models---so that it can learn about, and make informed decisions about, the environment within which it exists. This is especially challenging when the environment exhibits both stochasticity and partial-observability.
A commonality among many different types of models is that they are able to make predictions---probabilistic or otherwise---about future outcomes. These predictions play a central role in the agent's methods for decision-making (planning) and learning.
This thesis develops a recently introduced approach to modeling, in which predictions serve as the model's representation of its current state. A general framework for building models, called the predictive state representation (PSR) is examined in depth, and theoretical results and algorithms are developed for PSRs, laying the foundation for building models using predictive representations of state.
PSRs are examined in terms of their expressive power, by examining the class of environments that can be modeled using PSRs as compared to other common approaches for building models. It is shown that PSRs are at least as expressive as many other common approaches. Algorithms are developed that leverage the predictive representation of state in order to learn a PSR model based on the agent's experience with the environment. Furthermore, techniques are developed to allow an agent to make optimal decisions about its behavior, in the context of sequential decision problems---where any choice may have far-reaching consequences.
In addition, an extension of PSRs is presented, which incorporates a memory of the past with predictions about the future. Learning and decision-making algorithms are also developed for these memory-PSRs.
The work in this dissertation lays the groundwork for how predictive representations of state may be used for building models, by examining the expressive power of these models, and by developing algorithms and the necessary theoretical results for learning and planning.


ABSTRACT Population ageing is a key challenge confronting European policy makers. Ageing is a complex issue, requiring a value-driven approach to law and policy. However, there has been limited consideration of what values are driving ageing law and policy in the European Union, or if these values are appropriate. Drawing on an empirical study of United Kingdom (UK) legal policy documents, this paper identifies and critiques the primary values and objectives driving ageing law and policy in the field of employment. It is argued that the values driving UK law and policy are often contested, contradictory and under-defined, and there has been limited thought given to how they should be prioritised in the event they conflict. Thus, there is a serious need to reconsider the approach to age and employment taken by policy makers, and to clarify better the key values on which law and policy rest.


Reducing variability in a manufacturing process lowers system cycle times. Semiconductor manufacturing is a variable process due in part to product mix, reentry lot flows, batching, and machine breakdowns. This paper examines the issue of identifying machines that introduce variability into the system and constrain the system capacity. We develop a new X-factor contribution measurement, the complete X factor, that considers processing time variability and lot arrival variability among the constraining qualities of the machine groups. This new measure uses machine level data to indicate the normalized system cycle time which has typically been estimated by the ratio of the entire process time and the raw processing time at the end of production. With this measure it becomes possible for factory floor managers to identify a capacity constraining machine and its impact on the overall cycle time directly. We first qualitatively present the justification of the complete X factor for representing the normalized cycle time using queuing theory. Then, the complete X-factor measure was tested on a full-scale simulation model to demonstrate its accuracy for detecting capacity constraining machine groups and for representing normalized cycle time. We also explore the propagation of variability and the effect a highly variable machine group has on product cycle time and cycle time variability in relation to process routing. In a full-scale model machines identified by the complete X-factor contribution measure (CXC) measure lowered cycle time as effectively as highly utilized machines by adding capacity or streamlining breakdowns but had a more prominent effect on lowering cycle time variability. After a brief study on the propagation of variability, the CXC measure identified a lower utilized backend process that reduced cycle time and cycle time variability of the system


Composite particles are composites that contain particle or powder-shaped reinforcing materials. Particles as reinforcing materials greatly determine the mechanical properties of composites because they carry the load distributed by the matrix. The particle size, shape, and material are factors that influence the mechanical properties of particle composites. The friction component material that is intended for brake lining applications is strongly influenced by the size of the particles and the direction of loading. On the other hand it is necessary to step up the particle size optimization which will affect braking performance, which includes: friction numbers, wear, friction time and friction temperature produced. Therefore this study is aimed at optimizing the particle size against hardness, wear resistance and friction of aluminum powder in rice plant fiber reinforced composite. In this study, the materials used in the experimental process were rice plant fiber, fiberglass, aluminum powder and polyester resin. After the material is processed into the composite, hardness is tested using the durometer shore hardness method, after that, wear and friction testing were conducted. The results show the smaller the size of the aluminum powder, the harder the composite. The smaller the size of aluminum powder, the less wear of the composites. The failure of the adhesive was seen in the specimen tested for wear.


This paper describes preconditioning methods for real-time algorithm of nonlinear receding horizon control. Nonlinear receding horizon control requires a solution of a finite-horizon optimal control problem at each sampling time. Although the problem can be solved by a fast algorithm called C/GMRES, calculation may fail for some stiff systems. By introducing preconditioning methods such as block Jacobi or ILU preconditioner to a part of solving linear equations in the algorithm, it is possible to obtain a more accurate solution and to make the algorithm more numerically robust. The preconditioned algorithm is evaluated in a numerical example and is demonstrated in a hardware experiment of position control for hovercrafts connected by a string.


In this paper, design of reversible full-adder circuit using Lithium niobate based Peres gates is proposed. The results are verified using beam propagation method and MATLAB simulations.


OBJECTIVE
To study the changes of DNA repair genes and enhanced anti-tumor effect of cisplatin induced by mifepristone in human ovarian cancer drug resistance cells.

METHODS
The alterations of cisplatin concentration producing 50% inhibition (IC50 ) in the COC1/DDP cell lines were examined by methyl thiazolyl tetrazolium (MTT) assay. RT-PCR and flow cytometry were used to analyze the changes of the mRNA of ERCC1, BRCA1, hMLH1 genes and cell cycle and apoptosis. Subcutaneous implantation of COC1/DDP was established in nude mice and the enhanced anti-tumor effect of cisplatin by mifepristone was observed in vivo.

RESULTS
Cisplatin IC50 values of COC1/DDP cell were decreased from (3.71 +/- 0.38) microg/ml to (3.18 +/- 0.46), (1.95 +/- 0.14), (0.64 +/- 0.18) microg/ml respectively when treated with 2.5, 5.0, 10.0 micromol/L mifepristone. Mifepristone could down-regulate the mRNA levels of ERCC1, BRCA1, hMLH1 genes and enhance G0/G1 phase block effect of cisplatin, and 2.5, 5.0, 10.0 micromol/L mifepristone combined with cisplatin increased rate of cell apoptosis from 0.08% to 5.11%, 9.13% and 12.24% respectively. The percentage of inhibition of xenograft tumor volume in combined treatment group was 70.1%, which was significantly different (P < 0.05).

CONCLUSION
By down-regulating ERCC1, BRCA1, hMLH1 genes, blocking G0/G1 phase, and increasing apoptosis rate, mifepristone could enhance anti-tumor effect of cisplatin.


It's always worth taking the time to reappraise your approach to management and making sure that staff are being recognised, motivated and rewarded appropriately, says Jacqui Mann.


This paper deals with the results of different treatment done on high Strength concrete with different waste materials, like Bagasse ash, Waste foundry Sand and Jute fiber. the disposal of this waste leads to land pollution and is very tricky and time consuming process. The results in this study shows that the bagasse ash cannot be used much quantity in high strength concrete due to its water absorbing nature it reduces the workability and strength of the concrete after particular replacement with cement. Waste foundry sand can be used in same quantity as in normal concrete. Its behavior does not changes with grade of Concrete. Waste Jute fiber is a not used more than 2% due to reduction of Strength n the concrete.it also increases the water absorption bt decreases the lateral risk factors like shrinkage in the concrete. Using of waste material in this type of hish strength concrete can make the concrete ecofriendly because it reduces the waste and helps to reduce the pollution by disposing the waste.


The Chongming comprehensive training hall adopts a single-layer aluminum alloy spherical shell structure with a rise span ratio of 1 / 9, which is a small rise span ratio structure. Through the selection of structural system, this paper introduces the composition of single-layer reticulated shell structure, the relationship between structure and architectural modeling, indoor space and architectural lighting. Combined with the small rise span ratio structure, the elastic and elastic- plastic ultimate bearing capacity of aluminum alloy reticulated shell is studied. It is suggested that only the elastic-plastic ultimate bearing capacity of aluminum alloy reticulated shell should be checked, and the ultimate load factor should be 2.0. The failure mode and ultimate shear capacity of the joints are obtained by shear capacity test.


Vaccines are one of the most important, safe and efficient interventions to protect people from illness, disability and death. In recent years several new viral outbreaks where no vaccines are currently available were reported worldwide. Therefore, the development of flexible processes for the production of vaccines is urgently needed. This project aims at developing a platform process for the production of different viral vaccines. The core technology is based on the fact that large recombinant genes coding for selected, foreign antigens can be inserted into the genome of a well-established virus vaccination vector. The vaccine delivers the selected antigens directly to macrophages and dendritic cells, the most potent and effective antigen-presenting cells, thereby triggering a specific immune response to the selected antigens. As a replicating vector, the vaccine continuously expresses antigens even after immunization. This setup results in a powerful, antigen-focused immune response, which is expected to confer long-term immunity as shown for the measles vaccine.


Crystals of Er3þ doped K2YF5 and K2YbF5 as well as stoichiometric K2ErF5 have been grown under hydrothermal conditions. Peculiarities of Er3þ luminescence in these crystals have been studied under different excitation wavelengths and, in particular, it has been discovered that in 5 at% Er:K2YbF5, the energy transfer (ET) efficiency from Yb3þ to Er3þ reaches 67%. Under near-IR excitation at 980 nm, this crystal is characterized by intense yellow up-conversion luminescence with CIE coordinates: x1⁄40.449, y1⁄40.465. Under UV and visible excitation at 355 and 532 nm, respectively, clear evidences of the downconversion process through the cross-relaxation have been found. The corresponding efficiency of ET from Er3þ to Yb3þ is 69%. These features make Er:K2YbF5 crystals attractive for developing luminescent upand down-converters for enhancing the performance of solar cells. & 2015 Elsevier B.V. All rights reserved. ий Б р


This paper briefly describes the past development of the Bali Strait small pelagic fishery, and presents the impact of increasing fishing pressure and climatic variable on the quantity of catch. This paper then presents an estimate of its rent potential and the impact of increasing fishing pressure on rent at different climatic conditions.


Twenty-seven of the 232 wild potato species (Solanum sect. Petota) have been hypothesized to be of natural hybrid origin. Prior molecular data have failed to support hybrid origins involving two other wild potato species, Solanum raphanifolium Cardenas and Hawkes and S. chacoense Bitter, and hybrid speciation has never been supported with molecular data in sect. Petota. This study was conducted to test the hybrid origin of Solanum × rechei Hawkes and Hjert. It is a locally common and weedy wild potato species from Argentina, occurring at the extreme southern end of the range of S. microdontum Wittm., and near the northern end of the range of S. kurtzianum Bitter, its two putative parents. Solanum × rechei is diploid (2n = 2x= 24) with triploid (2n = 3x = 36) populations, S. kurtzianum is diploid (2n = 2x = 24), and S. microdontum is diploid (2n = 2x = 24), with triploid populations at its extreme southern range. A prior study supported the hybrid origin of S. × rechei by intermediate morphology of natural and synthetic hybrids, reduced pollen stainability of the natural and synthetic hybrids, and distributional evidence. Our studies of new collections and prior germplasm collections fail to support the morphological intermediacy of S. × rechei, but lack of morphological intermediacy is common for many hybrids. Hybrid origin was instead verified by reduced pollen stainability and additive parent-specific single- to low-copy nuclear restriction fragment length polymorphisms (RFLPs) in S. × rechei. These data suggest that other wild potato species also may be of hybrid origin, which may help explain some of the taxonomic confusion in the group.


Recent advances in the real-time simulation of electric machines are linked with the increase in the operation speed of the numerical models retaining the calculation accuracy. We propose utilizing the method of average voltages at the integration step (AVIS) for the design of a three-phase induction machine's model in its natural reference frame. The method allows for avoiding rotational e.m.f. calculation at every step; in turn, the electromagnetic energy conversion is accounted by the change of flux-linkage. The model is integrated into the object-oriented environment in C++ for designing the computer models of electromechanical systems. The design of the model of an electromechanical system utilizing the proposed approach is explained in an example. The behavior of the numerical models of a three-phase IM has been compared for the set of conventional numerical methods as well as first- and second-order AVIS. It has been demonstrated that both first- and second-order AVIS methods are suitable tools for high-speed applications, namely, AVIS provides higher maximum possible integration step (e.g., first-order AVIS provides 4 times higher than the second-order Runge–Kutta method, and the second-order AVIS provides 2.5 times higher than the first-order method). Therefore, we consider the most preferable order of the AVIS method for the high-speed applications is the second order, while the first order may be a suitable alternative to increase the calculation speed by 30% with the acceptable decrease in the accuracy.


Capillary haemangioma is a rare condition that is difficult to diagnose preoperatively because of its rarity and nonspecific imaging findings. In this report, we describe a case of capillary haemangioma diagnosed by robot‐assisted thoracic surgery (RATS). A 72‐year‐old man was incidentally found to have an anterior mediastinal tumour on chest computed tomography. The preoperative imaging findings were indicative of thymoma, and surgical treatment by RATS was selected. The intraoperative findings suggested that the tumour was a haemangioma originating from the pericardiophrenic vein. The pathological findings revealed a well‐defined tumour with capillaries in a vascular‐like structure and some thrombus formation. The pathological diagnosis was capillary haemangioma. The patient was discharged unaided at 7 days postoperatively and no recurrence was observed at 16 months postoperatively.


Very often, building managers face the challenge of having to operate a building in the absence of the appropriate information about how it should function. This problem is one of the many reasons why buildings operate inefficiently and tend to consume excessive amounts of energy. Building Information Modelling (BIM) is an emerging technology which addresses the management of information throughout the Building Life-Cycle (BLC). Industry Foundation Classes (IFC) is a non-proprietary data model of BIM that enables effective data integration over the BLC. IFC is a rich data model which may represent the entire building, however most applications are interested in a subset of this model. Hence, it is necessary to filter the information exchange between different applications and Model View Definitions (MVD) is the methodology to define such subsets. This paper presents the development of a MVD for environmental and energy performance assessment to support building managers during operation.


Cell preparations from 49 cases of lymphoid malignancy were cultured to determine optimal culture conditions (in semisolid media). Colony growth was obtained in the majority of cases (73%) using the combination of phorbol myristate acetate (PMA) and lymphocyte-conditioned medium (L-CM). Cell surface marker studies of plated cells in 36 cases identified 31 to be B-cell type, 1 to be T-cell type, and 4 null-cell type. The morphology and markers of harvested cells were similar to plated cells, suggesting proliferation of neoplastic cells predominantly. A relationship was found between the degree of colony growth and the clinical course of the disease in lymphomas but not in chronic lymphocytic leukemia (CLL). The use of PMA in combination with other mitogens deserves further investigation as a colony growth stimulator in hemopoietic malignancies.


Cluster-based structure is not a new research topic but it still chal- lenges the scientists. In wireless sensor network, cluster-based is one of im- portant approaches to achieve effective network performance such as energy saving, throughput maximizing, end-to-end delay and maintenance cost de- creasing, etc. In this paper, we propose a clustering scheme which utilizes the geographical information in order to construct the clusters, and is used in un- derwater wireless sensor networks. First, we use the geographical information and skewness measurement to classify the underwater wireless sensor network into even or skew distributed; Secondly, we construct the clusters using also the geographical information and network type to elect a group of cluster head can- didates so that the networks can be maintained for achieving the high perfor- mance. Simulation results show that: the proposed clustering scheme can obtain higher throughput with less end-to-end delay as well as decrease energy con- sumption of the network.


In order to lower the pressure loss of valve e xi sting in piston type refrigerator compressor which reduces C.O.P. of the refrige rator,design optimization is made in the valve passage of the suction valve and discharge valve.The experiment shows the amend is viable and profitable.


Eczema is an increasingly common chronic skin condition affecting many children, often causing significant impairment to the quality of life for both child and family. Children with eczema have been identified as being at risk for sleeping, behavioural, and emotional difficulties. Parenting children with eczema has been recognised as a difficult task, posing unique challenges for parents. Dysfunctional parenting styles, low parent self-efficacy, and poor parental psychosocial health have been associated with the severity of the child's condition and behaviour. Majority of research in this area, however, is reliant on self-report measures. The current study aims to address this gap using observational measures. Participants were 50 parents of children with eczema aged 2 to 10, with concurrent behavioural/emotional problems or illness management concerns. The current study examined observed parenting practices and child behavioural reactions in parent-child interactions during illness management. A battery of questionnaires measured parent psychosocial health, parent-reported child eczema behaviour problems, and parent's confidence in managing these behaviours. It was hypothesised that poor parental wellbeing, low parent self-efficacy for the management of eczema behaviour, and observed ineffective parenting practices would be associated with a higher frequency of observed and parent-reported child eczema behavioural problems. It was also hypothesised that parent factors would uniquely predict observed and parent-reported child eczema behaviour problems over and above socio-demographic variables. No association between parent factors and observed child behaviour was found. However, parent-reported child eczema behaviour problems were associated with parent factors, as predicted. Furthermore, self-efficacy for the management of child eczema behaviour problems predicted parent-reported problematic child eczema behaviour problems over and above socio-demographic variables. Findings and implications are presented and discussed.


When a person tells a biographical story communicating something about himself, he is making a presentation of what personality psychologists call "narrative identity." Much first-person online content, from professional publications, personal blogs, and of course social media, falls into this category of "stories of the self." Interestingly, people on the receiving end of these presentations don't always accept them. Examples abound on Web 2.0 publishing platforms of one person writing that another has his own story wrong: That he is drawing the wrong conclusions about his experiences, and laying claim to a mistaken identity as a result. This paper explores people's investment in the narrative identity presentations of others, and how the discursive context of Web 2.0 publishing informs their response. I draw on interviews with two individuals about pieces they wrote objecting publicly to other people's stories. The first posted an essay in the reader-generated content section of the website Jezebel about a first-person piece from the New York Observer, in which a 22-year old woman who had purchased a Manhattan apartment described herself as a "normal 20-something," rather than a rich person. The interviewee objected to the writer's classification of herself as normal, and the implication of merit he believed that classification carried. The second interviewee is a conservative blogger who took issue with an essay by a "daddy blogger" about the guilt he feels when he ogles women. The daddy blogger believed his experiences with powerful women had turned him into a feminist; the conservative blogger wrote that they had turned him into a man ashamed of natural impulses. I discussed with these writers 1) why they took an interest in the narrative identities of others; 2) what they hoped to accomplish with a public response, and 3) how the discursive context of the exchange influenced their behavior. I argue that when people dispute others' narrative identities, they may be using those identities as stand-ins for broader social values: Narrative identities are easily understandable and socially inflected, and thus make good proxies for social issues. Web 2.0 publishing platforms provide a discursive context conducive to the use of narrative identities in public debates about such issues, because they encourage response, provide a sense of disconnect from the subject of discussion, and give responders access to a potential audience. In this sense, social media are helping to turn the personal into the political in very public ways. Title: From Diaries to Profiles: The Rise of Public Intimacy Bio: Cristina Miguel is a PhD Candidate in Communications and a Teaching Assistant at the University of Leeds. Part-Time Lecturer at Leeds Metropolitan University


The possibility exists that primary-secondary cooperation may be more efficient at an international level and between organizations rather than between individual journals or services. Partly to test these hypotheses, the International Council of Scientific Unions Abstracting Board (ICSU/AB) established a Working Group on Cooperation among Editors. It has met regularly with wide international participation. One symposium, sponsored by the Working Group, was held in London in July 1973. The purpose of the discussions has been to improve the services rendered between primary and secondary publications. Among these are provision of statistical and fiscal information, of indexing and abstracting procedures, and of terminology and nomenclature. Primary journal editors can provide proper titles and abstracts early copies, and informed criticism of published abstracts and indexes.


this chasm can be bridged is by making use of the training in Western discourse analysis to generate a new, culturally suitable paradigm (p. 61), of which CNDS is a prime example. Shi concludes his book by announcing a "call-to-arms"; that is, by extending an invitation to scholars and students from developing and under-developing countries to create their own "culturally appropriate and productive systems of research" (p. 199), which should be brought into the international academic forum. By bringing greater numbers of culturally distinct paradigms and approaches to the international stage, the international playing field will move away from the dominance of "Western" thought to achieve a balanced approach. How scholars and students respond to his invitation remains to be seen. For now, perhaps after reading the book, they may share my admiration for Shi's efforts to "level the playing field."


Thorium Molten Salt Reactor-500 (TMSR-500), one of the Generation IV nuclear reactors, is designed by Thorcon International, Pte. Ltd, which is projected to be built in Indonesia. The reactor core is radially surrounded by B4C shielding, but not the upper part. As the silo hall sits above the reactor core and is accessible by reactor personnel, the dose rate must be calculated in the area to ensure the workers receive an annual dose below the acceptable limit. The dose rate from neutrons and photons as the result of fission reactions are the only sources to be calculated in this research, without taking the source from fission products into account. This research aims to obtain the dose rate distribution of neutrons and prompt photons using Monte Carlo code MCNP6. The reactor was assumed to operate at a nominal thermal power of 557 MWth. Dose rate calculation was obtained from flux Tally F4 and converted into dose rate using Dose Energy Dose Function (DEDF) factor. Conversion factors of flux to the dose were based on ICRP-21 and ANSI/ANS-6.1.1 1977. The result of the calculations showed that the distribution of neutron and prompt photon fluxes does not reach the silo hall.