The purposes of this study were to find out an evaluation scale that could predict wear comfort and to investigate the effect of the skin-contacting fiber type on the subjective sensation and microclimate. Sensorial evaluation was basically followed by the Human Perception Analysis (HPA) interviewing 144 consumers. Sixteen female subjects were participated in the sleeve wear test with and without wearing vapor permeable water repellent outerwear. Experimental sleeves were constructed using the same double knit by turning inside out to control other material effects except the skin-contacting fiber type, hence each different side of double knit, cotton side and the cotton/polypropylene blend side, was next to skin in each trial of the experiment. As results, it was noted that the term representing a combined feeling of thermal and wetness sensation, and muggy appeared to be a powerful language to measure perceptual responses of human subject among five dimensions of evaluation. although the ordinary users did not use the term very often. As for the comfort properties of double knits, it seemed that subjects slightly more preferred polypropylene/cotton blend to cotton as the skin-contacting fiber type when they wore outerwear and their skin were covered with sweat, although the result was rot statistically significant and need to be confirmed under higher work load.


The authors describe the sensitivity and crosstalk characteristics of a long-wavelength monolithically integrated four-channel photoreceiver array. This receiver consists of 4 p-i-n PDs, 24 JFETs, and 28 level-shift diodes. The device is fabricated using MOVPE-grown crystals and a Be ion implantation technique. The receiver chip demonstrates a sensitivity of between -30.6 and -31.4 dBm, and crosstalk below -20 dB over its operating frequency range. Sensitivity deterioration due to crosstalk is demonstrated and is shown to be a critical factor in system performance. The crosstalk is mainly due to parasitic inductances on the external power supply circuits.<<ETX>>


Across all age groups, management of type 1 diabetes (T1D) places substantial responsibility and emotional burden upon families. This study explored parent perceptions of the burdens of caring for very young children with T1D.


This article reports on an assessment of a framework for planning and sequencing e-learning student interactions and its capacity to accommodate critical student interactions in a graduate leadership curriculum delivered through hybrid e-learning technologies.


This paper aims to provide the results of our analysis of the fire and explosion hazard probability of the second and third level gas stations in downtown areas by using the G·M Lake Hoff method. While analyzing the explosion scenarios and the damages the fire and explosion results have brought about,we have adopted the pool fire method in our case study samples with a detailed discussion of the heat radiation destruction consequences,with the two kinds of gasoline tanks,50 m3 and 30 m3,being considered.We have also worked out the actual safety distance from the storage tanks of the second and third level gas stations,which should be 13. 4 m and 11. 3 m,respectively. The results of our analysis can be taken as the reference to checking whether the safety distance of the gas station is enough. For example,to meet the needs both of safety and convenience,measures are recommended to be taken to rectify and reform the hazard gas stations through studying the relationship between the gas supply and its demand. If the supply exceeds the demand,the gas stations should be downgraded or canceled or moved to the more appropriate locations in a safety distance. However,if the supply is not enough for the local residence,strict fire and explosion preventive measures should be taken to get rid of any likely fire and explosion accidents. While illustrating the process of the fire safety liabilities,we have taken the gas station distribution in Harbin for example. The result of our investigation and analysis has made us know that 23 percent of gas stations fail to meet the safety distance requirement. Actually,the demand quantity has now been and will be even in the next 10 years remaining much less than that the stations already in business now. Therefore,it is necessary to reduce and even cancel some gas stations which prove not to be in real need so as to ensure the safety and security of the residence and buildings around them. And,therefore,we have pointed out in this paper that measures are to be taken to regulate and rectify the relationship between the supply and demand of the fuel gas. If such measures can be taken successfully,great improvement can be seen with the fire and explosion safety distance in comparison with the current situation. Thus,we believe that the new method we have proposed will be proved more humane and rational in line with the actual needs for healthy development and expansion of urban living communities.


Superdiversity has brought with it a multitude of thingsone of which being, the increase in the number of Third Culture Kids (TCKs). The purpose of this research is to add to the current literature on TCKs, as well as, to showcase the importance of taking upon a social constructivist approach to view the concepts of culture and belonging. Accordingly, the conception of identity would also be adjusted. The first phase of the project involved a literature review to expand the perimeters of TCK. I then conducted interviews with 10 participants. The last phase involved the transcription and analysis of these interviews. Upon the examination of these accounts and by way of challenging deep-seated perspectives, it becomes clear that there is a dire need to move away from stagnant outlooks of identification and belonging.


Despite fairly heavy rainfall, the Bhutan Himalayan foothill region of Assam has been facing serious water scarcity problems mainly due to the subsurface structure and soil condition. The local people of the region with their community efforts and traditional knowledge have developed a water management system locally known as Dong-bandh. This traditional canal water system provides the most reliable source of water to the people residing in the area. Besides the canals, they also collect water from the streams, natural springs, and wells. The quality of water is getting deteriorated over time under the influence of the growing population and their activities in the upstream areas. The present study is an attempt to investigate the status of water accessibility in the area and the quality of the drinking water used by the people. For this study, data and information have collected through field investigation, GPS survey, focus group discussion, and interviews with some key informants. A total of 14 drinking water samples were collected randomly from 14 foothill villages (both from the ground and surface) and tested to determine various physiochemical characteristics. The results were compared with the WHO and BIS/ ICMR water quality standards. Finally, the status of water quality was analyzed in terms of the Water Quality Index (WQI). The WQI values were found to lie between 21.75 to 502.38.


The mountainous woodland covering with dense vegetation has complex terrain deformation, poor surface stability and rare obvious markers, which brings challenges to the accurate registration of multi-temporal remote sensing images. Viewing multi-temporal satellite image sequences as a whole matrix, we conduct RPCA matrix decomposition to generate a low-rank matrix and a sparse matrix, where the column of low rank matrix can be considered as the stable surface image. Referring to this, the original image registration is operated. It solves the difficulty to distinguish the real change of scenery and the distortion of remote sensing image in the case of unstable features and lack of obvious markers. Based on the feature matching method and local coordinate transformation and resampling model, the multi-temporal images are respectively registered with their stable surface images, and finally realize the batch accurate registration of multi-temporal satellite images of mountain forestland.


The U.S. Department of Energy (DOE) has performed a department-wide scoping of its packaging and transportation needs and has arrived at a projection of these needs for well into the twenty-first century. The assessment, known as the Transportation Needs Assessment (TNA) was initiated during August 1994 and completed in December 1994. The TNA will allow DOE to better prepare for changes in its transportation requirements in the future. The TNA focused on projected, quantified shipping needs based on forecasts of inventories of materials which will ultimately require transport by the DOE for storage, treatment and/or disposal. In addition, experts provided input on the growing needs throughout DOE resulting from changes in regulations, in DOE`s mission, and in the sociopolitical structure of the United States. Through the assessment, DOE`s transportation needs have been identified for a time period extending from the present through the first three decades of the twenty-first century. The needs assessment was accomplished in three phases: (1) defining current packaging, shipping, resource utilization, and methods of managing packaging and transportation activities; (2) establishing the inventory of materials which DOE will need to transport on into the next century and scenarios which project when, from where, and to wheremore » these materials will need to be transported; and (3) developing requirements and projected changes for DOE to accomplish the necessary transport safely and economically.« less


Abstract The article examines the manner in which public-policy for satellite broadcasting has been made in West Germany and France, the two countries currently leading developments in satellite broadcasting technology in Western Europe. A special theme of the two case studies is that of the complex relations and potential contradictions between industrial/technological policy and broadcasting policy, between the wider economics of satellite broadcasting and its cultural dimension. The article demonstrates a common pattern, as policy makers in both countries have been constrained to develop a broker role between competing aims and between national/regional pressures and international pressures. Nevertheless, both ideological and structural differences remained of enduring importance in establishing the parameters of policy making, and produced different, as well as similar, policy outcomes in the two countries. The question of 'sovereignty' is also set within the wider European context and the article examines responses at this latter level, in particular the European Community.


We describe an 11-year-old boy who presented with meningoencephalitis and was found later to have Kawasaki disease. The neurologic outcome of this patient was excellent, with full recovery without any neurologic deficit. The case report is followed by a review of the neurologic associations and complications of Kawasaki disease.


There have been very few modern anthropological studies made in Cuba; none, to my knowledge, on urban class structure or movements. Perhaps the comparative absence of Indians there has caused research workers to bypass it. Other studies have mainly concerned themselves with analyzing historical data or with plotting africanisms in Cuba. Now that a new revolution has disturbed the social structure on that island the Spanish expatriate is taking a new look, perhaps an apprehensive look, at his place in that structure. This paper is an attempt, preliminary and descriptive, to assess the role he has played in the twentieth century. Ever since the sixteenth century rule of the Catholic Kings the Spanish system has at least required previous authorization for emigration from the Iberian peninsula when it did not prohibit it. Many of these restrictions were lifted in 1853; thereafter, during the nineteenth century, a great wave of emigration began to the Spanish colonies of Cuba, Puerto Rico and the Philippines as well as to other Ibero-American countries such as the Argentine-still the point of highest preference today. The reasons for coming to Cuba in the late nineteenth and early twentieth centuries were simple. The Spaniard may have been sent by his government in an official position or as a member of the military occupying forces (at least until 1898) and later resigned or defected from his post to settle there in a civilian capacity: this was certainly true of many Spanish soldiers after the Cuban War of Independence. Many have told me that one of the most potent reasons for emigration from Spain was to avoid military service especially during the unpopular African wars in Morocco in 1859, 1893, 1909, 1911 and 1920. Moreover, exile from the homeland can be either voluntary or imposed but the line is hard to draw in some cases. One of the direct effects of the Spanish Civil War was the move from Spain of many thousands


In this paper I study the place granted to the Irish legend of Breogan in the books and essays written by the Galician polymath Manuel Murguia. Five are the main points I address here. How did he narrate the legend of Breogan? How did he understand it? How did he adapt the Irish story to his own vision of the Galician past? Which were the functions that the legend performed? Which were the sources of information used by Murguia to know the story of Breogan? Finally I reflect on the issue of Murguia's contributions to the popularity of Breogan in contemporary Galician culture.


From the angle of managers,a study is made on the sequencing and grouping of the disclosure degree of non-financial indicators concerned about by the management staffs which reflect their interests requirement and realization ways.The purpose is to help enterprises to gain understanding and support from the managers,to help people understand the realization degree of the interests requirement of managers,evaluate the efforts enterprises have made to protect and increase managers' benefit,and strengthen the disclosure of non-financial indicators of enterprises to managers.


The utility model relates to a multi-plane high-flexible tubular fracture external fixer, which comprises a support rod, a bone needle fixer which can be arranged on the support rod and a bone drawing and pressing regulator arranged on the support rod. A plurality of types of multi-plane high-flexible tubular fracture external fixers can be formed by different combinations. The utility model is suitable for the external fixation of tubular fracture of different positions and types, especially the utility model has good effect on open and comminuted fracture, and simultaneously, the device has the functions of flexible regulation, firm and reliable fixation, bone pressurizing and bone extending.


In this paper, a dual-element MIMO antenna without adding any decoupling structure is presented. The MIMO antenna consists of two symmetric inverted-L elements with the antenna spacing of only 9 mm (0.1 λ at 3.5 GHz). The isolation between antennas is reduced by pattern diversity. |S<inf>11</inf>| < −10 dB and |S<inf>21</inf>| < −16 dB are achieved over the band from 3.48–3.6 GHz. Compared with the antenna without decoupling, the isolation is improved by 11 dB, whereas the envelope correlation coefficient (ECC) is reduced from 0.14 to 0.04.


For long distance and large capacity transmission problems, high-voltage direct current (HVDC) transmission is a suggestive alternative. In the design and construction process of HVDC transmission project, analysis on overvoltage and resonance characteristic of key equipment is indispensable. This paper employs a method to construct a passive broadband model for the converter valve. The Vector Fitting (VF) method is adopted to get a fitting curve with frequency impedances measured off at hundreds of sample points. Afterwards, the corresponding passive equivalent broadband circuit is built via passive algorithm and synthesis procedure. The applicability of the method to our model is confirmed by comparing the simulated and measured data. The double exponential model parameters of overvoltage are calculated according to the definition of International Electrotechnical Commission (IEC) and the voltage distribution of the valve module composed of the key components is characterized, in favor of which the key components can be optimized.


It is well documented that financing decisions by firms can signal valuable information about that firm. Our goal is to determine whether financing decisions by firms can signal valuable information about large stakeholders who have a substantial investment in those firms. In particular, we focus on financing decisions by firms after they had been partially acquired to determine whether these decisions signaled information that affected the values of their corresponding partial acquirers. We find that some financing policies by partially acquired firms may not only signal valuable information about themselves, but may also signal valuable information about their corresponding partial acquirers. We also find that the magnitude of the signal for the partially acquired firm that enacts a financing policy is dependent on the degree of monitoring imposed by the respective partial acquirer.


Production reports from a set of Chinese factories reveal very rapid productivity growth from 1980 to 1991. To understand the underlying factors, the effects of work effort and labor organization are separated from the productivity estimates. Data analysis reveals that these two effects jointly explain most of the measured productivity growth during this period. This result suggests that (1) very substantial productivity growth can be realized for economies in the take-off stage even without substantial pure technological advancement, and (2) in reforming the Chinese state factories, there will have to be a more difficult second stage to confront their technological backwardness. Copyright 2001 Western Economic Association International.


Objective To perform cloning and expression of the AhpC gene of Helicobacter pylori in order to construct a basis for the investigation work of vaccine to prevent and treat Helicobacter pylori infection.Methoods The AhpC gene of clinical isolate was amplified from Hp chromosomal DNA by PCR techniques.The PCR product was inserted into the expression vector pET-11c.The recombinant vector pET-AhpC was identified by DNA sequencing and transformed to E.coli BL21(DE3) for expression under inducing of IPTG.The protein was purified by Ion-Exchange chromatography and identified by SDS-PAGE and Western blot.Results The PCR product was shown consisting of about 597 base pairs.It was determined using restriction enzyme digestion and sequencing methods that the gene segment inserted into the recombinant vector was identified to GeneBank show 97% identity.SDS-PAGE was shown that expressed up to 28.7% of total somatic protein by IPTG induction.The purity of protein reached more than 70% after purification.The protein could be recognized by rabbit anti-Hp blood serum.Conclusions The express vector pET-AhpC was successfully constructed and the protein can be highly expressed in E.coli.


Two kinds of real-time correction methods(alternate filtering method and integrated filtering method) were examined,firstly,to detect how these two methods can work only for water-stage updating without discharge correction;and secondly,to select the timesaver one.The calculation of flood forecasting for river section from Cuntan to Wanxian of Yangtze River verifies that the alternate filtering method performs better than integrated one.


Objective To investigate severe lung injury of three Chinese patients with refractory plasma disease after the treatment of bortezomib.Methods To analyze clinical data of three Chinese patients with refractory plasma disease after the treatment of borezomib.Results Severe pulmonary complications appeared in 4-12 hours after application of bortezomib.One patient was saved by high-dose dexamethasone.Conclusion Late stage and high tumor load may be two precipitating factors in pathogenesis of severe lung injury.


Bovine pancreatic ribonuclease A (RNase A, EC 184.108.40.206) has been extensively studied from the structural, mechanistic and functional points of view. Within the protein folding context, it constitutes a good model of study although a rather complicated one due to the presence in the native state of four disulphide bonds and the existence of two X-proline peptide bonds in cis conformation. Most of these studies has focused on the alteration of cysteine or proline residues to study, from a kinetic point of view, the formation of the disulphide bonds or the characterization of the species present in the heterogeneous non-reduced unfolded state, respectively. In these work we have used site-directed mutagenesis to change the characteristics of a postulated chain folding initiation site (CFIS) in RNase A


Maintaining a particular specific growth rate throughout a culture is essential for reproducible product quality in industrial bioprocesses and therefore, is a key sequence for the step-up from Quality by Analysis to Quality by Design. A novel and robust Process Control Tool designed to achieve close control of the specific growth rate in fed-batch cultures by regulating an exponential substrate feed is under development and shows high potential for general applicability.


In 1983–1984, 9.8 million prescriptions were written for the 12 most common psychotropic drugs that are available under the Pharmaceutical Benefits Scheme. Our analysis shows that, of these prescriptions, 59% (374 per 1000 persons) were for the four most commonly prescribed benzodiazepine agents; 34% (216 per 1000 persons) were for the five main antidepressant agents; and 7% (41 per 1000 persons) were for the three main phenothiazine agents. In the period from 1977–1978 to 1983–1984, prescription volumes were relatively stable for antidepressant and phenothiazine drugs. Fluctuations in the prescribing of individual benzodiazepine agents are discussed. Older patients and women of all ages receive the majority of the psychotropic drug prescriptions that are written by Australian general practitioners.


In this paper, non-polynomial spline method for solving the generalized regularized long wave (GRLW) equation are presented. In this paper, we take deferent spline functions . The stability analysis using Von-Neumann technique shows the scheme is marginally stable. To test accuracy the error norms L2, L∞ are computed. Also, the change in conservation quantities a r evaluated which are found to be very small. To illustrate the applicabi lity and efficiency of the basis, we compare obtained numeric al esults with other existing recent methods. Moreover, interaction wo and three solitary waves are shown. The development of th e Maxwellian initial condition into solitary waves is also shown and we sh ow that the number of solitons which are generated from the Ma xwellian initial condition can be determined.


[1] We have constructed a high resolution 3-D shear wave velocity model of the upper mantle beneath the Grenville Province in the lower Great Lakes region. A two-plane wave tomography method was applied to fundamental mode Rayleigh wave data recorded at 35 broadband seismic stations. Rayleigh wave phase velocities were obtained at 15 periods from 20 s to 143 s and then inverted for shear wave velocity variation. A high velocity lid to ~150 km depth is imaged beneath most of the studied Grenville Province. One low velocity anomaly of −4% appears at a failed rift in the northeast above 100 km depth, coinciding with the Great Meteor hot spot track and the high seismicity band, which can be interpreted as high temperature and high iron and/or volatile content related to the hot spot activity. Low velocity anomaly of ~2% at the depths of 100–200 km are found beneath the east of Lake Ontario and Lake Huron where the lithosphere is relatively thin. These anomalies follow the NW-SE trend of the slow indentation imaged on the continental-scale models. We conclude that the location of low velocity anomalies is not only related to the hot spot track but also controlled by the pre-existing lithosphere morphology and strength. A high velocity column appears between southern Lake Ontario and the Appalachian front centered at ~100 km depth. It is likely caused by high Mg content at the formation of the lithosphere or the presence of ecologite or garnet phases generated during the opening and closure of the Iapetus Ocean.


Focused on identifying hierarchical heavy hitters (HHH) in multiple dimensions from network management perspective, this paper presents a framework of finding HHHs in network measurement systems and proposes a heuristic algorithm on finding static and dynamic HHH in two dimensions. Our algorithm dramatically reduces the space and time complexity comparing with other previous algorithms. We implement and test it in a typical local network and the experimental results verify the effectiveness and efficiency of the algorithm.


The utility model discloses a polluted water in-situ control and purification device adopting aerated air stripping to lift a water flow. The device comprises a device rack floating platform, a platform support, a water passing grid barrel and a water flow lifting device extending into water, wherein the bottom of the water passing grid barrel is communicated with an isolation outer barrel; a porous sieve plate is arranged at the bottom of the isolation outer barrel; the bottom of the isolation outer barrel is communicated with a water inflow grid barrel; the isolation outer barrel is filled with suspended fillers; the device rack floating platform is connected with a grid barrel supporting ring arranged on the water passing grid barrel. The device has the advantages that the device can adopt a single-barrel or double-barrel structure; wind power or solar energy or wind power and solar energy can be transformed to electric energy.


In one remarkable week, and in the face of a horrifying pandemic, information technology and systems were harnessed to dramatically transform education and office work It wasn't always pretty, but the IT infrastructure worked, at least for those fortunate to have access to it Tele-medicine, remote work, distance education - concepts long touted but sparsely implemented - suddenly essential and transformational Now that we have made it through the immediate impact of the pandemic, the long term implications and consequences are emerging What is this pandemic driven, but IT shaped, new normal? What does it mean for families, careers, and businesses? What does it mean for higher education and our discipline? Our panelists will explore the challenges faced by doctoral students and early career professors, two career families, and small businesses But we will also ask them to help identify new opportunities, particularly for research, new modes of education and greater engagement with industry


Damage to the areas of the brain that are responsible for higher visual processing can lead to severe cerebral visual impairment (CVI). The prognosis for higher cognitive visual functions in children with CVI is not well described. We therefore present our six-year follow-up of a boy with CVI and highlight intervention approaches that have proved consistently effective.


With the increasing carbon emissions worldwide, lithium-ion batteries have become the main component of energy storage systems for clean energy due to their unique advantages. Accurate and reliable state-of-charge (SOC) estimation is a central factor in the widespread use of lithium-ion batteries. This review, therefore, examines the recent literature on estimating the SOC of lithium-ion batteries using the hybrid methods of neural networks combined with Kalman filtering (NN-KF), classifying the methods into Kalman filter-first and neural network-first methods. Then the hybrid methods are studied and discussed in terms of battery model, parameter identification, algorithm structure, implementation process, appropriate environment, advantages, disadvantages, and estimation errors. In addition, this review also gives corresponding recommendations for researchers in the battery field considering the existing problems.


Fms-like tyrosine kinase 3 (FLT3) mutations have been found in about 30% of acute myeloid leukemia (AML) cases, and the most common form of FLT3 mutation is internal tandem duplication (ITD) in the juxtamembrane domain, which is associated with poor prognosis. In non-clinical studies, quizartinib clearly inhibited FLT3 signaling pathways in FLT3-ITD–mutated human AML cells, leading to potent growth inhibition. When quizartinib was given to mice bearing human FLT3-ITD AML MV4 -11 cells, the tumor regression was observed. In addition, quizartinib inhibited the viability of the on midostaurinresistant human FLT3-ITD AML MOLM-14 cells, and exerted potent in vivo anti-tumor activity. Quizartinib showed clinical benefit in patients with FLT3-ITD–mutated relapsed/refractory AML in phase III QuANTUM-R trial (NCT02039726). Quizartinib significantly prolonged median survival time compared with salvage chemotherapy (6.2 months vs 4.7 months; HR = 0.76 [95% CI, 0.58–0.98; P = 0.0177]). The most common TEAEs were thrombocytopenia, nausea and anemia. A phase III QuANTUM-First trial (NCT02668653) in patients with newly diagnosed FLT3-ITD–mutated AML is now ongoing. Non-clinical and clinical profile of quizartinib suggests its potential for further clinical investigation of optimum treatment sequence with FLT3 inhibitors for the AML patients.


In this study we investigate the near-fault rupture directivity effect (NFRD effect) in strong ground motion during the 2004 Rumoi earthquake (Mj 6.1) using Hybrid simulation, which uses a combination of 3D-FDM (3D Finite Difference Method) and SGF (Stochastic Green's Function). We calculated seismograms near the fault area (20 km x 20 km) and made a PGV distribution map. Strong ground motions over 70cm/s, which are affected by the NFRD effect, appeared around the surface projection line of the upper edge of the rupture area. We extracted the predominant area of the NFRD effect on near-source strong ground motions using the criteria of Ohno et al. (1998). Additionally we attempted to select a large PGV zone in the predominant area of the NFRD effect using a PGV attenuation curve (Si and Midorikawa, 1999). As a result, we successfully selected a large PGV zone affected by the NFRD effect near the fault area.


When the listed company was treated specially, the ST Company will be under tremendous pressure. So the Commission will take action. Firstly, it will monitor the ST Company to improve the operation and production conditions. Then, it will clean up bad assets. At last, it will put into good assets. After all these actions, the ST Company will restore normal listed company. In this paper, we use financial distress prediction model to analysis financial statements and related management data. After analysis, we can tell business operators and other related party the Pre-losing hazard which the company will confront. We use A-share listed small and medium-banks as samples to construct financial distress prediction model. Fist, we will use principal factor analysis to extract common factors which can reflect financial information. Then, we will use the decision tree analysis to find out the common factors which can give maximum gain ratio. So we can provide the banks with comprehensive financial risk control indicators and we can find out the reasons for financial crisis. So these companies can do early job to avoid business losses and get ST treatment.


At least 60% of nursing home residents are diagnosed with a chronic disease. Chronic
diseases require ongoing medical treatment and need to be managed with diet. If not treated and
managed, chronic diseases can limit daily living activities, leading to poor quality of life.
Therapeutic diets such as low sodium, cardiac, and diabetic meal plans are usually necessary to
manage chronic diseases. However, these meal plans are blamed for decreased intake and
increased risk of malnutrition in the nursing home population. The recent culture change seen in
nursing homes resulted in the liberalization of diets. However, to maintain self-determination,
residents are requesting more restrictive meal plans to manage their chronic conditions and more
control of their therapeutic selections. This ethnographic study investigates the perception of
nursing home residents with diabetes following restricted diets' as it relates to meal choice,
food/food service satisfaction, support for self-determination, and how nursing home residents
with diabetes manifest self-determination. Sunny Peak Living Center in Ross Township is one of
four non-profit Allegheny County nursing homes in the Pittsburgh area dedicated to enhancing
quality of life of residents and families. Resident observations took place at meal time, council
meeting, and socials for over 11 weeks. Interviews were conducted with 12 Caucasian, cognitively
alert residents, diagnosed with diabetes and prescribed a Consistent Carbohydrate Diet, including
7 men and 5 women, ranging in age from 64-94. Semi-structured audio-recorded interviews were
transcribed and analyzed using constant comparison to develop themes. Residents perceive
therapeutic diets as helpful in the treatment of diabetes and feel diets are necessary to maintain
health and food service satisfaction is maximized by choice. Residents manifest self-determination
by exercising meal choice and expressing preferences and opinions about food/foodservice
satisfaction during meals as well as socials and resident council.


Sir, Epidemic diseases affecting substantial population of the world is not new and the list of epidemics and pandemics are reported as early as 429 BC.[1] A pandemic is defined as "an epidemic occurring worldwide, or over a wide area, crossing international boundaries and usually affecting a large population." In late December 2019, China reported cases of patients with pneumonia of unknown etiology which was classified as epidemic and later upgraded as pandemic. The virus was previously known as "2019 novel coronavirus" and the disease it caused is named as coronavirus disease (COVID-19) which appears to be of zoonotic origin.[2] The World Health Organization (WHO) raised a global alert on the need of containment, surveillance, detection, isolation, and contact tracing.[3] Countries across the world responded to this unprecedented pandemic by harsh containment measures. The Indian government responded with the invocation of Disaster Management Act and Epidemic Diseases Act; closing the entire establishment except essential services on March 24, 2020, which was termed as lockdown.


Objective:To investigate the effects of Wenyang Huazhuo Tongluo Prescription(温阳化浊通络方)on the phenotype transformation and migration of human skin fibroblast induced by Wnt-1.Methods:Medicated serum of Wistar rats was got by intragastric administration of Wenyang Huazhuo Tongluo Prescription and normal human skin fibroblasts were cultured in vitro.The rats were divided into a blank control group,a Wnt group and a Wenyang Huazhuo Tongluo Prescription group.Respectively after 24,48,72 hours,RT-PCR and Western blot were used to detect the expressions of α-SMA mRNA and protein,and Transwell was used to detect the migration of fibroblasts.Results:Compared with the blank control group,human skin fibroblasts a-SMA mRNA and protein expression in the Wnt group could be induced in different time(P 0.01),and the number of migration increased(P 0.01).Compared with the Wnt group,human skin fibroblasts a-SMA mRNA and protein expression in the Wenyang Huazhuo Tongluo Prescription group were obviously inhibited(P 0.05,P 0.01) and their migration were prevented(P 0.01).Conclusion:Medicated serum of Wenyang Huazhuo Tongluo Prescription can inhibit the phenotype transformation and migration of human skin fibroblast induced by Wnt-1,having the potential to prevent or delay systemic sclerosis fibrosis.


Abstract : I am pleased to be here to discuss 5. 1993, the Government Information Security Act of 1999, which seeks to strengthen information security practices throughout the federal government. Such efforts are necessary and critical. Our work has shown that almost all government agencies are plagued by poor computer security. Recent events such as the denial of service attacks last month indicate the damage that can occur when an organization's computer security defenses are breached. However, Mr. Chairman, let me emphasize that the potential for more serious disruption is significant. As I stated in recent testimony, our nation's computer-based infrastructures are at increasing risk of severe disruption. The dramatic increase of computer interconnectivity, while beneficial in many ways, has provided pathways among systems that, if not properly secured, can be used to gain unauthorized access to data and operations from remote locations. Government officials are increasingly worried about attacks from individuals and groups with malicious intentions, such as terrorists and nations engaging in information warfare.


This study examined the usability challenges and emotional reactions blind college students experienced in accessing educational materials and communicating with professors and colleagues through online technologies. A case study approach was adopted. Five students were interviewed regarding their online learning experiences using Blackboard, a popular Course Management System. Analysis of the interviews revealed that the blind students found Blackboard poorly accessible, which affected their academic achievements. However, despite their frustrations and feelings of marginalization, the study also showed that the blind students were motivated and optimistic of their successes. The research suggests that academic administrators and CMS designers work jointly with adaptive software developers to create enhanced user interfaces, ensure universal access and usability of online technologies, and reduce educational inequities and frustrations encountered by blind students.


The article describes a detailed analysis of the modernisation procedure for cadastral data in Poland in both theoretical and practical aspects. Modernisation of the cadastral system is an essential tool to ensure both the continuity in time and the timeliness of cadastral data. In Poland, the function of the Cadastre is served by a public register known as the Land and Building Cadastre which records the actual data on the ground, resulting from the current state of ownership or use. Legal data are stored in a separate register known as the Land and Mortgage Register. The Cadastre in Poland has numerous disadvantages; however, its advantage is that no construction of the system anew is required. The existing cadastral data need to be skilfully used, and the quality of cadastral data needs to be adjusted to international requirements through the use of technical and legal guidelines in the field of modernisation. The research material consisted of source texts of existing legal provisions equivalent to an act of legislature and implementing regulations as well as technical documentation for modernisation works performed in southern Poland (Małopolskie Voivodeship). The method of comparative analysis of the compliance of modernisation work results with national requirements was applied. An analysis of the adopted indicators for cadastral data evaluation, using the selected example, showed that the properly performed modernisation of the Land and Building Cadastre may become a tool for improving the land management and administration process.


Prediction equations for coronary heart disease (CHD) risk are useful tools that inform clinicians and patients about the absolute risk for developing CHD. A basic principle in CHD prevention is that the intensity of risk-reducing interventions should be based on the individual patient's absolute CHD risk. In the current era of human immunodeficiency virus (HIV) infection and highly active antiretroviral therapy (HAART), knowing one's CHD risk and acting to reduce it have become imperative to long-term survival. Given the increased life expectancy as a result of HAART, more HIV-infected persons will experience complications not related to HIV per se and will reach an age at which they are at increased risk for developing CHD.

However, existing CHD risk prediction equations were not developed in HIV-infected adults or children. In the general population, CHD risk prediction models derived from the Framingham Heart Study estimate the risk of total CHD (angina pectoris, myocardial infarction [MI], CHD death)1 or estimate the risk for hard CHD end points (MI, CHD).2 The traditional risk factors used to predict CHD risk and how risk factor alterations affect CHD outcomes in HIV-infected and HIV-seronegative people are summarized in the Table. The estimates of the relative effects of traditional risk factors on CHD outcomes appear similar between HIV- and non–HIV-infected patients. However, they are based on only 2 studies in HIV-infected patients. Although traditional CHD risk factors may operate in the same manner in HIV patients as in the general population, there may still be a need to identify and evaluate HIV-specific CHD risk factors and equations, to refine existing CHD prediction equations, and to develop new HIV-specific CHD prediction equations for adults, adolescents, and children. To date, Framingham CHD risk predictions have performed reasonably well when applied to HIV-infected patients. We need to evaluate …


Waveguide flanges pose a major limitation to precise measurements above 110 GHz. This paper describes measurements on a new flange which is compatible with the standard UG-387 waveguide interface (MIL-DTL-3922/67C) but which offers significant improvement in alignment and repeatability. The ring-centered flange has a precisely machined boss centered on the waveguide aperture. The bosses of a mated pair of flanges are aligned by a separate coupling ring. The new flange is sexless and the contact surfaces are accessible for mechanical lapping to repair damage. Measurements of WR-5 waveguides (140–220 GHz) with ring-centered flanges, enhanced UG-387-type flanges, and a new flange proposed by Lau and Denning are compared.


Reaction of [Re3(mu3-S)(mu-S2)3Cl6]Cl with an ionic liquid composed of 1-ethyl-3-methylimidazolium bromide (ImBr) and aluminum bromide (AlBr3) formed a new trinuclear rhenium sulfide cluster compound Im3[Re3(mu3-S)(mu-S)3Br9]Br with nine terminal bromo ligands.


A virus was isolated by PK15 cells culture from skin vesicles on nursery pigs in Jiangxi province.The virus could be replicated in PK15 cells without cytopathgenic effects(CPE).The virus isolate was identified as swinepox virus(designated as SWPV-JX01) by PCR which amplified P35 gene of SWPV,and phylogenetic tree analysis based on P35 gene showed that SWPV-JX01 was 97.9% identity to reference strain(AF410153.1) of SWPV.The rabbits and Kunming mice were artificially infected by SWPV-JX01,and the P35 gene of SWPV was detected by PCR in different tissues of infected rabbits.The results indicated that SWPV-JX01 could be replicated in rabbits in vivo,but could't be replicated in mice in vivo.


1. An autoradiographic study was made of the regenerative mechanism of the corneal epithelium of albino rabbits.2. Regeneration of the corneal epithelium is achieved not only by migration of the epithelial cells from the non-injured area but also by active mitosis in the basal cells of the regenerating epithelium of the injured area.3. The area adjacent to the wound edge contributes an important share to the regeneration of the epithelium in the form of DNA synthetic cell band.4. 3H-cytidine is incorporated into the nuclei as well as into the cytoplasms of all the cells of the normal rabbit corneal epithelium.


The goal of a large (25 m) submillimeter telescope with high aperture efficiencies up to frequencies of ~ 1 THz requires a wavefront sensor able to measure the telescope surface figure to an accuracy of order 1 micron, better than has been achieved to date in the millimeter/submillimeter (MSM) regime. On the other hand, the recent availability of largeformat submillimeter detector arrays suggests that new techniques can be applied. In particular, using submillimeter focal plane arrays, variants of interferometric pupil-plane wavefront sensing techniques familiar from the optical/infrared (OIR) regime could perhaps be applied profitably in the MSM. However, while many possibilities can in principle be considered, many of these possibilities would be unwieldy in the MSM, because of the need for large off-axis reflective optical elements, and the consequent sizeable optical layout. However, the overall size of an interferometer can be minimized by making use of a common-path interferometer. Here we thus consider the applicability to MSM wavefront sensing of a rather simple common-path pupil-plane interferometer, specifically a scanning version of the fixed-phase phase-contrast interferometers described in different contexts by Zernicke1 and Dicke2. Both transmissive and reflective solutions for the needed phase shifting interferometers are possible, but here we focus on the reflective case as a proof of principle. Such a common-path phase-shifting interferometer has several potential advantages: relative simplicity, compactness, ease of manufacturability, reduced systematic effects, and high accuracy.


AbstractThis work was carried out to explore the relation among thermophilic cellulolytic fungi, which are of industrialimportance. There was no report found about the genetic relationship of fungi, which are used to produce industrial enzymes.So the aim of the study was to observe the similarity among different cellulolytic fungi on genetic level, which will providethe background to understand the correlation among cellulase producing systems of these fungi. Eleven (11) fungi werestudied for genetic diversity using the Random Amplified Polymorphic DNA (RAPD) a PCR based molecular marker system.In this regard twenty universal decamers used for RAPD resulted in 1527 numbers of bands observed during comparison ofall wild strains. Maximum polymorphism was generated with GLA-07. Average numbers of bands per 20 primers were 65-72.An Interesting feature of the study was the similarity of Humicola insolens with Torula thermophile, more than with theother members of the Humicola family. This genetic pattern affects the physical structure of the fungi. Spores of Torulathermophila are more related to Humicola insolens than to its own family. Similarity between the two was found to be 57.8%,whereas between Humicola lanuginosa (Thermomysis lanuginosus) and Humicola grisea it was 57.3%. Apart from this,similarity between Talaromyces dupontii and Rhizomucor pusillus was 51.5%. Least similarity was found in Rhizomucorpusillus and Humicola grisea, which was 18.7% and Chaetomium thermophile and Sporotrichum thermophile, which was18.3%. Genetic similarity matrix was constructed on the basis of Nei and Li's index.Keywords: genetic diversity, cellulolytic fungi, DNA fingerprinting, RAPDSongklanakarin J. Sci. Technol.34 (6), 607-613, Nov. - Dec. 20121. IntroductionThe fungi constitute a most fascinating group oforganisms exhibiting great diversity in form, structure, habit,life history and mode of nutritional and mycelial tropic stage,which adequately distinguish the fungi as separate kingdom(Hawksworth et al., 1983). Microbial sources such as fungiare well recognized to produce a wide variety of chemicalstructures, several of which are most valuable pharmaceuti-cals, agrochemicals and industrial products such as enzymes.The world of fungi provides a fascinating and almost endlesssource of biological diversity, which is a rich source for ex-ploitation. Fungi interact with their hosts, and also withabiotic variables in the environment (Manoharachary et al.,2005).Thermophilic fungi are a small assemblage in mycotathat have a minimum temperature of growth at or above 20°Cand a maximum temperature of growth extending up to 60 to62°C. As the only representatives of eukaryotic organismsthat can grow at temperatures above 45°C, the thermophilicfungi are valuable experimental systems for investigation ofmechanisms that allow growth at moderately high tempera-ture yet limit their growth beyond 60 to 62°C (Cooney andEmerson, 1964).The properties of their enzymes show differences notonly among species but also among strains of the same spe-cies. Genes of thermophilic fungi encoding lipase, protease,xylanase, and cellulase have been cloned and over expressedin heterologous fungi, and pure crystalline proteins havebeen obtained for elucidation of the mechanisms of their


In this paper, we present kernel methods for the approximation of quantities of interest which are derived from solutions of parametric partial differential equations. From a priori information on the parameters in the differential equation, we explicitly construct a reproducing kernel Hilbert space containing the quantity of interest as a function of these parameters. Based on this problem-adapted reproducing kernel, we suggest a regularized reconstruction technique from machine learning in order to approximate the quantity of interest from a finite number of point values. We present a deterministic a priori error analysis for this reconstruction process yielding a subexponential convergence order due to the smoothness of the quantity of interest as a function of the parameters. The error estimates explicitly take into account the error of the numerical evaluation of the quantity of interest for fixed sets of parameters. This leads to a coupling condition between this evaluation error which contains the ...


The growth and annealing of aluminum films containing up to 3%* silicon have been studied by electron-microscope and electron-diffraction methods. The films were prepared by condensing the vapors from heated aluminum-silicon alloys onto rock-salt substrates. The textures and defect structures observed in these films, both before and after annealing, are discussed.


The ongoing shift from an industrial to a digital economy is a significant global phenomenon. However, the driving forces behind and the tactical approach to digital transformation are still unclear to the construction industry, thereby posing challenges for construction enterprises seeking to undergo digital transformation. Therefore, this paper conducted an investigation on the subject, including the following: (1) the 17 influencing factors in the complex system of digital transformation of construction enterprises were screened and summarized from four perspectives: Environment, Technology, Organisation, and Resources. The attributes of the influencing factors were analyzed using the Decision-Making Experimentation and Evaluation Laboratory (DEMATEL) method, and the key factors were identified. (2) The Total Adversarial Interpretive Structure Model (TAISM) method was used to develop a multi-perspective adversarial recursive structure model with integrated impact values, which reflected the interrelationships between the influencing factors and the hierarchical structure. (3) Based on the analysis of the influencing factors of digital transformation of construction enterprises, the clear path mechanisms were elucidated and suggested measures from the internal and external perspectives of government and construction firms were recommended. The results can offer theoretical backing and serve as a stepping stone for the digital transformation of the construction industry.


Project-based firms are transforming their business models in order to add services to their offers, with the consequence that their business projects are beginning to be conceived as long processes in which servitization takes place.


Motor short circuit contribution is a real consideration in low-voltage systems. It must be considered in deciding whether to apply series ratings of overcurrent protective devices. Virtually every electrical system has motors in it some place. This paper: confirms the existence of low voltage motor short circuit contribution by test; examines some of the relevant literature; explores typical installations; and recommends application guidelines.


This study aimed to analyze the Ethical Leadership in the management of the Valle of Momboy University. The theoretical foundation was based on theoretical assumptions of Cortina (1998) (2005), Covey (2005) and Goleman (2000). From the methodological point of view, the research is descriptive, with field design. The study population was represented by 124 teachers and 21 managers, with a sample for 56 seconds. The information was collected through a questionnaire consisting of 22 items, using a Lickert scale with five response alternatives. The instrument was validated through the trial of three experts and the reliability was also determined by Combrach Alpha coefficient, obtaining a value of rtt = 0.96 and the calculation of the two halves


A convenient method is developed for mass producing porous bulk metallic nanostructures with high purity, fine nanostructures of high specific surface areas, and improved mechanical performance, at low cost and high production rates. Alloys are first mechanically pretreated and grain-refined using the convenient surface mechanical attrition treatment (SMAT) and then dealloyed in an etchant solution. The reactive metal component can be effectively removed at an accelerated rate, while the more inert metal component forms a porous structure with finer porous features (e.g., ligament size) and largely suppressed "self-coarsening" effects (the undesired structural rearrangement upon long-time soaking in the etchant that results in larger structural features reducing the material overall surface area), leading to a bulk metallic framework of a well-defined nanoporous morphology and a remarkable thickness of the mm order. Monolithic supercapacitor electrodes of superior performance are enabled by coating NiIIIOOH onto the bulk porous Cu frameworks fabricated using this novel method.


A study, part of a 5-year investigation (1991-1995) of patterns of implementation of literature-based instruction in schools serving large numbers of children from low-income families, recounts children's literacy experiences as observed in a third-grade classroom in an urban school in upstate New York. The primary goal was to understand the various factors influencing literacy instruction in several such schools. During the ermArza of th,:t study, teachers participated on two levels: on the first level, brief teacher interviews and classroom observations were conducted to assess various factors concerning literacy instruction, such as type/quantity of books in the classroom library, planning for literature instruction, and evaluation of literary knowledge; on the second level, 4 of the 11 teachers volunteered to serve as teacher collaborators during all 5 years of the project. Collaborators were involved in extensive formal and informal interviews, focus group meetings, classroom observations, and collaborative teaching units with the researchers. Data were analyzed both quantitatively and qualitatively to describe the nature of literacy instruction the course of the study. Analysis tried to make sense of the representative third-grade teacher's instruction by exploring the constructs which underpinned her notions about teaching, learning, and work. Results fall into five categories: (1) focus on personal life, (2) perceptions of children, (3) curricular influences, (4) perspectives on change, and (5) school and district context factors. (Contains 12 tables, one figure, and 62 references. Attached are library worksheets, a classroom literacy inventory protocol, and a student observation instrument.) (NKA) ***********************************************************t1********** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** Access Denied: A Five-Year Study of Literacy Instruction Provided to Poor, Urban Elementary Children Sherry Guice Gregory W. Brooks National Research Center on English Learning & Achievement U.& DEPARTMENT OF EDUCATION Office of Educational Research and improvement EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) This document has been reproduced as received from the person or OrpaniZation originating it O Minor changes have been made to improve reproduction quality. Points of view or opinions stated in this document do not necessarily represent official OERI position or policy. University at Albany, SUNY University of Wisconsin Madison University of OklahomaUniversity of Washington


Summary The quantity of γ- and δ-lactones and of methyl ketones produced when bovine butterfat was heated in the presence of water vapour and the absence of air, and hence the flavour quality of the butterfat, varied widely with the diet of the lactating cows. There was a marked increase in the γ-dodecanolactone potential when the cows were transferred from pasture to a mixture of chopped lucerne hay plus crushed oats but not when they were transferred to lucerne hay only. Feeding crushed sunflower seeds, whose oil was protected against biohydrogenation in the rumen, but not feeding sunflower meal from which the oil had been extracted, raised the γ-dodec-cis-6-enolactone potential, lowered the saturated δ-lactone potential and the methyl ketone potential and simultaneously raised the proportion of linoleic acid in the butterfat at the expense of fatty acids up to and including C16.


The essay analyzes the superiority and inferiority of such fundamental conditions as nature, resource, geography, industry and traffic in Jiyuan. Considering the actual regional distribution, the essay puts forward measures of developing the superior regions with characteristic agriculture.


[1] The 2-day wave is investigated in a three-dimensional model of the nonlinear primitive equations. Extending upward from the tropopause into the thermosphere, the model is forced stochastically by fluctuations of tropospheric wave structure. The behavior recovered is broadly consistent with linear calculations of the Rossby-gravity normal mode in the presence of instability. The mode's amplification depends sensitively upon details of the zonal-mean flow, which determine instability through a reversal of potential vorticity (PV) gradient. On the other hand, the mode's period and structure are robust. They retain much the same form under a variety of conditions. The response is sharply discriminated to wave number 3 and westward periods of 2.0–2.3 days, even though forcing is broadband. Under January conditions, strong easterlies and the accompanying reversal of PV gradient enable the mode to amplify through sympathetic interaction with the mean flow. The amplifying signal eventually emerges from random variability, which is excited by broadband forcing. Amplification continues until eddy velocities approach 70 m/s, whereupon the signal saturates. Horizontal mixing then ensues, destroying the meridional gradient of PV, which in turn limits instability and further amplification. Under June conditions the response fluctuates randomly during the entire integration, with no evidence of sustained amplification. Nevertheless, it too is sharply discriminated to westward periods of 2.0–2.3 days, achieving eddy velocities of 10–20 m/s. The sharply discriminated response appears even when a reversal of PV gradient is absent, leaving the mean flow stable. Under all of these conditions the structure of eddy stream function Ψ′ is nearly barotropic, with antisymmetric character between the hemispheres. Eddy motion assumes the form of a wave-number-3 pattern of equatorial gyres, reducing in the tropics to v′ and strong cross-equatorial motion. The pattern is very similar to the limiting structure of the 2-day wave observed by UARS. Although magnified in the summer stratosphere and mesosphere, the structure of Ψ′ is global, with a phase reversal between the hemispheres. The modal structure extends upward into the thermosphere and, albeit weaker, as low as the tropopause.


The early ontogeny of the pinnately, palmately, and ternately compound leaves in the Lardizabalaceae was studied by SEM. The leaf primordium of each of the three leaf types emerges as an identical short protrusion on the shoot apex; the leaf primordium produces the first leaflet initials laterally on its margin. Successive acropetal growth of the leaf axis and the following inception of the leaflet primordia are responsible for the pinnately compound leaf, whereas short basipetal growth accompanied with initiation of two or more pairs of leaflet initials results in a palmately compound leaf. If no elongation of the leaf axis nor additional inception of leaflet primordia occur during early ontogeny, a temate leaf ensues. COMPOUND LEAVES of angiosperms show their morphological diversity in that they are pinnate, palmate, or ternate. Such variation in the external leaf form raises a question about the difference in the developmental pattern of leaf growth. Since the early study of Eichler (1861), our knowledge of the morphology and histology of leaf development has increased a great deal. However, most previous studies were based on observations of simple leaves and on anatomical descriptions of the activity of marginal and/or apical meristems during leaf development. Early publications dealt with the morphogenesis of young foliar organs in angiosperms and suggested that the localization and depression of the marginal meristem activity forms the basis of leaflet primordia inception, and thus the various types of compound leaves are developed (Goebel, 1905; Foster, 1935; Troll, 1939; Hagemann, 1970, 1984; Kiirbs, 1973a, b; Kaplan, 1984). Recently morphological and histological studies have been carried out comparing pinnate compound leaf ontogeny to that of simple leaves (Merrill, 1979, 1986a, b, c; Jeune, 1982a, b, 1984; Dengler, 1984; Gould, Cutter, and Young, 1986).


Ejaculatory duct cyst is a very rare case. We report a 26-year-old man with primary infertility complaining of aspermia since before marriage, precisely since the first wet dream. General physical examination and hormonal levels were in normal values. The cyst was visualized through abdominal TRUS, MRI and abdominal ultrasound (USG). The sperm detection test was performed before and after repaired by TURED. Before repair, the sperm was absent at Cowper's gland secretion, post orgasmic urine and post massage prostate. After repair, sperm was detected in cyst aspiration fluid and useful to distinguish ED cyst between the Mullerian duct and utriculus cyst. In addition, after one month post repaired, the sperm concentration, motility and morphology increased. The improvement of sperm quality is useful to determine the infertility program whether IVF, IUI or natural pregnancy. Keywords: Ejaculatory duct cyst, Male infertility, Sperm detection.


One of the main elements which are used by poets is description in lyrical literature. As a formalist poet, Nezami Ganjavi also considers description in his unique work. He uses skillful description in this beautiful work to make tangible the concepts and story and to introduce the people, things, and phenomena. Since the subject of this study is "The grammatical aspects of description and aesthetics in Leili and Majnun of Nezami", it aimed to analyze the descriptions of Nezami in terms of adjectives and structure of adjectives in Leili and Majnun of Nezami based on the poem evidences. In this study, in addition to the description of objects and phenomena, the Nezami's techniques such as simile, metaphor, and irony have been considered. All of these highlight the manifestations of lovers. In his work, Nezami Ganjavi (Ganjei) has used words and group of words such as compound adjectives which have the highest frequency.


The first objective of this study is to analyse the elasticity of labour-output and labour-wage for professional and technical labours. The second objective is to project the requirements of these two occupational categories for year 2015 and 2020. The analysis is based on data of four selected services subsectors, namely, professional business, education, health and information and communication technology for the period 20002010. Data are obtained from the Service Industry Survey collected by the Department of Statistics Malaysia. The results show that the elasticity of labour-output is positive, while the elasticity of labour-wage can be positive or negative depending on the occupational category and sector. The manpower requirement for the professional and technical occupations depend on the output growth and the initial stock of employment, which are dominated by the education and information and communication technology sectors.


We introduce a model of squeezing and noise reduction in the Kerr effect that accounts for noise in all quadratures of the driving field. Consequently we show that Kerr squeezing is much more sensitive to driving noise than squeezing produced by second harmonic generation (SHG). We experimentally demonstrate this sensitivity using a nonlinear system that tunes between strong classical SHG and Kerr behaviours. Whilst the system experiences strong squeezing in the SHG limit, it experiences no squeezing in the Kerr limit, although it does experience strong classical noise reduction, or 'classical squeezing'.


Abstract We report on low temperature measurements of the electrical resistivity, the Hall coefficient and the magneto-resistance in hydrated potassium intercalation compounds of 2H-TaS2, where the stoichiometry and hence the charge transfer can be varied.


This paper discussed on the structural properties of the PMMA/TiO2 nanocomposite films prepared using sonication-solution casting method. The structural properties of the nanocomposite films were compared by mixing the self-prepared TiO2 (~12 nm) and the commercially available TiO2 (25 nm) in the PMMA. The well dispersion of self-prepared TiO2 nanopowder was observed in the FESEM micrograph. XRD results show that the self-prepared TiO2 nanopowder decrease the crystallinity of the nanocomposite. Further, FTIR reveals that the interaction between the PMMA and TiO2 nanoparticles were detected.


Diurnal birds of prey are predominantly monogamous (Newton 1979). Alternative mating systems like polygyny, polyandry, or cooperative breeding are rare, but have been recorded in at least 16 species of raptors (Newton 1979, Faaborg and Bednarz 1990, Heredia and Donfizar 1990, Tella 1993, Tella et al. 1996). Nonmonogamous relationships are easily overlooked when working with unmarked individuals and are almost certainly more widespread than published records show (Newton 1979). Polygyny in birds of prey has only been regularly observed in harriers (Circus spp.) although it has been occasionally recorded in another nine species (Newton 1979, Hiraldo et al. 1991, Tella et al. 1996) and seems to


BackgroundMedial sphenoid wing meningiomas still present a difficult surgical challenge especially when they are large in size and involve the cavernous sinus. MethodsThis is a retrospective study of 27 consecutive cases of medial sphenoid ridge meningioma treated surgically at the Neurosurgery Department, Alexandria University, in the period between 2005 and 2009. We assessed early and late postoperative morbidity, extent of resection, and long-term outcome. The mean follow-up period was 26 months. ResultsMost patients in this series harbored large tumors (mean tumor diameter was 4.3 cm). There was no postoperative mortality in this series. The most common postoperative morbidity was cranial nerves dysfunction. The Dolenc approach was the most commonly used. Total resection was achieved in 48% of cases. In case of subtotal resection, postoperative radiotherapy was carried out to control the growth of residual tumor. ConclusionsThis study with several other similar studies show that total excision of medial sphenoid ridge meningioma is possible even in the presence of large tumor size and cavernous sinus involvement with no mortality and acceptable morbidity rates. The primary goal of management is the improvement of the functional outcome. The Dolenc approach is ideal in dealing with these tumors as it minimizes the intraoperative blood loss and brain retraction and decompresses the optic nerve.


The work is dedicated to converting microwave radiation to heat. The article analyses different ways of heating residential and utility areas. Attention is paid mainly to infrared heating. Ceramic materials suitable for converting microwave radiation to heat from refractory ceramic composites are disclosed. The cooling curves of these materials after microwave heating are characterized in detail. The paper also presents a description of a microwave reactor with a fireclay brick together with the parameters of the living room heating.


The use of video and games plays an important role in the language learning process. Not only are they favored methods of learning for students, rather this paper attempts to show that videos and games are a couple of the best language learning aids for teachers to include in their lessons. Ideas presented here are in there to help give guidelines on how to incorporate video and usage in into the lessons of English language as well as why it is important to include these methods in conventional curriculum. The use of video and games in the classroom can be used to motivate students, enhance their grammar and pronunciation, and teach culture. This paper provides the insight into different researches on the topics of video and games as language learning aids. It also provides some guidelines for future research. It is intended to provide teachers with some idea for using these tools in combination with course books, and it contains a variety of suggestions for activities to use in the EFL classroom in Bosnia and Herzegovina.


A kind of nonionic surfactant-α-pinenemaleamide ethanol was prepared by means of reaction of α-terpinene-maleic anhydride adduct(TMA) to diethanolamine without catalyst.The optimal synthetic conditions were as follows: molar ratio of n(α-terpinene-maleic anhydride adduct) to n(diethanolamine) was to 1∶2.2,reaction temperature-140 ℃,and reaction time-4 h.The yield was above 81%.The resultant was analyzed and characterized with IR,TLC,MS,and 1H NMR methods.Besides,its critical micelle concentration(CMC) and corresponding surface tension were measured to be 0.03 mol/L and 32.0 mN/m,respectively.


This paper examines two influential novels of the 18th century, Eliza Haywood's Anti-Pamela and John Cleland's Fanny Hill: or, the Memoirs of a Woman of Pleasure, to offer insights into the social norms, gender roles, and erotic attitudes of the time. Through a comparative analysis of the two works, this paper highlights their distinct literary traditions, concerns, and perspectives on the issues of eroticism, virtue, and gender relations. The study finds that while Haywood's Anti-Pamela critiques the excesses of the materialistic and libertine culture of the time, Cleland's Fanny Hill challenges the concept of virtue and decorum by emphasizing the complexities of human erotic desire. The paper argues that the two works offer unique and valuable perspectives on the social and cultural landscape of 18th century England, contributing to the ongoing debates on gender, social inequality, and erotic exploitation. This study provides a better understanding of the literary and cultural history of the 18th century and its relevance to contemporary discussions on the issues of gender and eroticism.


A Raman spectroscopic study of Na1/2Bi1/2TiO3-x%BaTiO3 (NBT-x%BT) single crystals with x = 0 and 5.6 has been performed as a function of temperature from 25 to 600 °C. The general features of the Raman spectra for the various compositions were similar over the region of the phase diagram investigated, with only subtle changes between rhombohedral (R), tetragonal (T) and cubic phases. The peaks were broad, with no significant narrowing on cooling through a phase transition. We find evidence of an oxygen octahedral rotational mode in the paraelectric state. On cooling near and below the ferroelectric Curie temperature, a gradual change in intensity of the A-O and B-O peaks occurred with decreasing temperature. Evidence of a ferroelectric → antiferroelectric transition was found near 200–250 °C, consistent with the onset of dispersion in the dielectric constant. The phase transition mechanism was discussed. The findings indicate the presence of a broad distribution of quasistatic local structural distortions...


Purpose

– The study aims to extend knowledge of practitioner beliefs amongst advertising agency creatives across three countries – Australia, New Zealand and Malaysia – regarding factors that impact advertising creative excellence in the advertising agency. The study also seeks to address views across Australian creatives and their clients.

Design/methodology/approach

– The design combined preliminary qualitative work using depth interviews with a subsequent questionnaire‐based survey of the various stakeholder groups. Opinions of Australian creatives are compared, using the same survey instrument, with those of a sample of Australian advertiser clients. The views of the various national groups of creatives are then compared using the same instrument.

Findings

– The results indicated that a group of factors encourage creatives, and to an extent their clients, to have high expectations of the achievement of optimal creative work. There was more agreement among the creatives across the three countries than agreement between the Australian advertisers and any of the groups of creatives. There were also differences evident between the views of Malaysian creatives, on the one hand, and their Australian and New Zealand counterparts, on the other. A finding that Malaysian creatives were in slightly more agreement with the Australian advertisers than were Australian and New Zealand creatives was unanticipated.

Research limitations/implications

– Identified limitations include failure to collect data from advertiser stakeholders (clients) in the non‐Australian countries. This meant that direct comparisons of client‐agency beliefs could not be made within these countries. The challenge now is to explore the reasons why the differences and similarities found exist.

Practical implications

– Changes to practice to be made as a result of this research relate to management of the structured transfer of information between agency and client stakeholders, and management of authority issues in this relationship, particularly across cultures.

Originality/value

– Provides cross‐cultural as well as inter‐organizational perspectives on advertising agency–client relationships.


High-contrast gratings fabricated in free-standing membranes of silicon nitride are a remarkable new platform for optomechanics, as they combine high reflectivity, low mass, and a high mechanical quality factor in a single device. In an effort to further improve on our earlier designs, we are now fabricating high-contrast gratings from stoichiometric silicon nitride. The new gratings have a diameter of 80 μm, a thickness of 250 μm, and are patterned in square membranes from 100 μm to 500 μm on a side. We find reflectivities R < 0.994 for these devices, and fundamental mechanical resonance frequencies above 1.5 MHz. In addition, we have incorporated HCGs fabricated from low-stress silicon nitride into a "membrane-in-the-middle" setup, and observe that the cavity transmission spectrum is distorted from a constant free spectral range of 3 GHz to one characterized by anticrossings separated by 72 ± 2 MHz.


T he introduction of treatment modalities such as thrombocytic therapy, antiplatelet therapy, anticoagulation, angiotensin-converting enzyme (ACE) inhibition, lipid-lowering agents, ,-blockade, as well as other therapies, has dramatically altered the management of coronary artery disease in the last three decades. These therapies have greatly improved our ability to treat angina pectoris and acute myocardial infarctions as well as protect the heart during and following cardiac surgery. However, despite the differing mechanisms by which these pharmacologic agents work, they all basically have one of two major effects on the ischemic heart: they either increase oxygen supply or decrease oxygen demand. It has recently become clear that improving the efficiency of the heart in converting oxygen into contractile work is another option for the treatment of coronary artery disease. Metabolic modulation is one such approach to improving cardiac efficiency (see references 1 to 5 for reviews). In particular, switching energy metabolism from fatty acid to glucose oxidation improves cardiac efficiency. "Metabolic modulation" is a novel and exciting alternative approach to improve the performance of dysfunctioning myocardium. Beneficial effects of agents that influence myocardial energy metabolism have been shown in experimental and clinical studies of ischemia reperfusion and heart failure. All these agents shift energy metabolism away from fatty acid toward carbohydrates,


By analyzing China's road traffic safety problems and development trends from 2004 to 2018 under the population change, this paper explores the impact of various population factors on the number of casualties in traffic accidents in China, and puts forward targeted prevention and management measures for the development direction of China under the new situation. Starting from the population factors of the number of floating population, population density, natural population growth rate, and urbanization rate, this paper collects panel data of traffic accidents of China from 2004 to 2018, and estimates the parameters using fixed effect model. Time effect variables are added based on traditional panel data, and a fixed-effect model is constructed to study the impact of road traffic accident deaths in China. The results show that from 2004 to 2018, China's population density and the number of deaths from road traffic accidents change in the opposite direction. The natural population growth rate and urbanization rate have positive changes with the death toll from road traffic accidents respectively. Therefore, this paper proposes appropriate preventive measures from traffic congestion, floating population management, traffic safety management, and other aspects to reduce road traffic accidents and property losses caused by demographic changes.


Most of the commissioning support services being set up by primary care trust staff to assist clinical commissioning groups have passed the second stage of the NHS Commissioning Board's business review process, although some quite narrowly.

A total of 25 regional NHS commissioning support services and the nationwide NHS Communications and Engagement Service submitted outline business plans and detailed financial information for "checkpoint 2" of the assurance process.

Fourteen of these organisations passed the …


The ability to estimate the motion of objects is crucial for robotic agents to act and interact in their environments. This is particularly challenging for non-rigid objects, as they exhibit complex dynamics with large degrees of freedom. This work presents a methodology to learn deformation models of 3D elastic objects based on graph networks. Our approach exploits physical reasoning by introducing soft constraints into the loss function during training. We evaluate the proposed method in a simulation framework developed for robotic manipulation tasks. Results show that such a physics-informed model is able to predict more accurate object motions with less data than a purely data-driven based model.


Electronic communication has become an essential part of consumers' everyday lives. Consumers rely on the internet as an alternative source of information pertaining to brands that can be accessed easily. As a result, electronic word of mouth (e-WOM) has become a force to be reckoned with that needs to be understood in order to be properly managed. This research investigates how the credibility of the brand as a source of information might be influenced by consumers' engagement in e-WOM and whether this influence subsequently reflects on their purchase intentions. The research findings indicate that indeed there is a relationship between e-WOM and brand credibility that reflects both directly and indirectly on the consumer's purchase intentions. Based on this, several recommendations are developed to help managers navigate their online presence in a way that specifically suits their consumers' internet usage patterns, in order to effectively manage available e-WOM on their brands.


4-Amino-1-azabutadienes
 2 underwent [3 + 3] cyclization with Fischer alkynylcarbene complexes of chromium and tungsten 1 to furnish high yields of substituted 3,4-dihydropyridines 3. The expected pyridine ring formation, which would result from cyclization/aromatization,
 does not take place. The process is thought to involve
 a 1,2-imidoyl group shift triggered by a 1,2-metal pentacarbonyl
 shift as the more characteristic steps. An X-ray diffraction
 experiment supports the proposed structure
 for the dihydropyridines.


This paper is on the fabrication of steel columns, used in the construction of a seven storey building. The core of the columns consisted of 12 in. X 8 in. joists, the cover plates being from one 14 in. X 1/2 in. on each side of the joist, to a 12 in. X 1 in. and a 1 f in. X 1 in. on each side, depending on the position of the column in the building. The lengths were from 15 ft to 30 ft and weighed up to 3Ja tons. Figure 1 shows a sample piece of the column with two cover plates on each flange of the rolled steel joist.


Power transfer allocation isone ofthemajorissues inderegulated power industry. Thispaper presents a hybrid technique forpower transfer allocation. Itisbasedon combining theexisting power flowtracing methodsthatdetermines the power sharefromgenerators tolineflowsand loads. The advantages oftheproposed methodaredemonstrated bythetests conducted on theIEEE30-bus systemandalso on a practical 25- busequivalent power systemofsouthMalaysia. Theproposed methodprovides better reliability andminimizes thelimitations ofconventional power flowtracing methods.


Through research on source of heat noise, this paper discusses the effect caused by heat noise, this paper discusses the effect caused by heat mist in CATV sysyem and puts forward two effective ways to reduce heat noise


Status of this Memo This memo provides information for the Internet community. It does not specify an Internet standard. Distribution of this memo is unlimited. Abstract Deployment of a Directory will benefit from following certain guidelines. This document defines a number of naming guidelines. Alignment to these guidelines is recommended for directory pilots.


We present III-Sb resonant cavity-enhanced (RCE) photodetectors suitable for gas detection in the mid-wave infrared. AlAsSb/GaSb DBRs and absorbers of bulk InAsSb or a type-II InAsSb-InAs SLS were grown on GaSb, allowing for operation at 3.72 μm or 4.52 μm, with linewidth Δλ 20x reduction in noise compared with a conventional nBn detector with full thickness absorber. At 3.72 μm, performance above the BLIP limit imposed on broadband photodetectors was found by calculating for the specific detectivity.


Dried amniotic membrane (AM) has been shown to have the potential to help and facilitate proper closure of gastric tissue defect post penetrating injury trauma. This study evaluated the difference of fibroblast count and collagen thickness in gastric tissue post penetrating injury using with and without dried AM as a biological dressing. A randomized experimental study on New Zealand rabbits treated to an artificial gastric penetrating injury. The samples were divided into two groups, control and treatment, without and with dried AM, respectively. Microscopic evaluation of the gastric tissue specimen was done using hematoxylin-eosin staining. Average fibroblast count in the control group was 70.90±10.26, and the group with dried AM was 91.00±10.82 (p = 0.000). The mean thickness of collagen in the control group was 3142.48±1271.29 µm, and the group with dried AM was 4703.71±1807.88 µm (p = 0.006). These results showed significant difference in fibroblast count and collagen density when gastric penetrating injury was treated with primary closure and dried AM. There is a significant difference in the number of fibroblasts and collagen thickness in the repair of gastric rupture using dried AM as biologic dressing compared to the control group.

 How to Cite this Article

 Pubmed Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono. Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count . SRP. 2020; 11(5): 583-586. doi:10.31838/srp.2020.5.78

 Web Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono. Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count . http://www.sysrevpharm.org/?mno=112441 [Access: March 30, 2021]. doi:10.31838/srp.2020.5.78

 AMA (American Medical Association) Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono. Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count . SRP. 2020; 11(5): 583-586. doi:10.31838/srp.2020.5.78

 Vancouver/ICMJE Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono. Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count . SRP. (2020), [cited March 30, 2021]; 11(5): 583-586. doi:10.31838/srp.2020.5.78

 Harvard Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono (2020) Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count . SRP, 11 (5), 583-586. doi:10.31838/srp.2020.5.78

 Turabian Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono. 2020. Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count . Systematic Reviews in Pharmacy, 11 (5), 583-586. doi:10.31838/srp.2020.5.78

 Chicago Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono. "Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count ." Systematic Reviews in Pharmacy 11 (2020), 583-586. doi:10.31838/srp.2020.5.78

 MLA (The Modern Language Association) Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono. "Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count ." Systematic Reviews in Pharmacy 11.5 (2020), 583-586. Print. doi:10.31838/srp.2020.5.78

 APA (American Psychological Association) Style

 Harisma Widhanar, Fendy Matulatan, Eddy Herman Tanggo, Edwin Danardono (2020) Differences of Dried Amniotic Membrane Effect on Healing of Gastric Tissue Post Penetrating Trauma Reviewed from Collagen Thickness and Fibroblast Count . Systematic Reviews in Pharmacy, 11 (5), 583-586. doi:10.31838/srp.2020.5.78


A organic polynitrile N,N,N′,N′-tetra(2-nitrilethyl)ethylenediamine was synthesized by the nucleophilic additive reaction of ethylenediamine and acrylonitrile.The N,N,N′,N′-tetra(3-aminopropyl)ethylenediamine was synthesized by the hydrogenation of N,N,N′,N′-tetra(2-nitrilethyl)ethylenediamine in the presence of catalyst Ni.Then a new branch-claw type polyamide was synthesized by condensation with N,N,N′,N′-tetra(3-aminopropyl)ethylenediamine and dimmer fatty acid.The molecular structure of the product has been characterized by means infrared spectrum(IR),nuclear magnetic resonance(NMR),elemental analysis,electros pray ionization mass spectrometry(ES-MS)and thermogravimetric-differential scanning calorimeter(TG-DSC).


Cybersickness is one of the notable discomforts associated with virtual reality(VR) applications. With the recent advancement of machine learning, we can train deep neural networks to detect cyber-sickness severity from the physiological and VR-image data. Prior researches found a correlation between physiological and VR-image data with cybersickness. In this study, I hypothesize to detect the onset severity of cybersickness. Finally, based on the severity level, automatically apply different cybersickness reduction techniques in real-time.


Three species belong to the genus Convolvulus L. from the Convolvulaceae family, new to Flora of Western Desert District were recorded. These species were Convolvulus cantabrica L., Convolvulus reticulatus Choisy and Convolvulus stachydifolius Choisy. Species were photographed, their taxonomical and ecological characters, as well as their geographical distribution in the Western Desert were demonstrated. Plant samples were collected, precisely identified, dried and herbarium specimens were prepared and deposited at Anbar University Herbarium (AUH). Some notes on habitat, flowering and fruiting periods were provided. The means and reasons that helped these species to be distributed in new places within the Western Desert District of Iraq were realistically discussed, it was found that there was no sample of the three mentioned species that were collected from the Western Desert District at all.


The phenotype of obesity has been attributed to multifactorial issues. A poorly balanced diet, associated with a sedentary lifestyle has contributed to the high incidence of the disease, in addition, causing changes in plasma parameters of the metabolism of carbohydrates and lipids. The aim of this study was to evaluate the influence of high carbohydrate diet in association with physical training on a treadmill exercise on the maintenance of retroperitoneal, inguinal and brown (BAT) adipose tissue (AT) and plasma levels of leptin, insulin and NEFAs, as well as the trained animals ability to perform the work on a treadmill exercise and the relative expression of Ucp1, Adra2 and Adrb3 in BAT and insulin receptor (Insr), leptin and its receptor, Ucp2, Adra2 and Adrb3 in retroperitoneal AT. Weaned Wistar rats (28 days) were distributed in the following groups: sedentary balanced control diet (SC), trained on a treadmill exercise balanced control diet (TTC); sedentary high carbohydrate diet (SD) and trained on a treadmill exercise high carbohydrate diet (TTD). The physical training on the treadmill exercise had progressive increases in exercise intensity, five times a week, lasting four or eight weeks. After this period, the animals were decapitated, AT was weighed and the plasma levels of leptin, insulin and NEFAs were determined. Subsequently, the mRNA levels of genes described above were determined by qRT-PCR methodology with the method of 2-Cq. The gene rRNA18S was chosen as normalizer. The treadmill exercise training did not reversed the weight gain of AT induced by diet. However, for the animals that received balanced control diet, there was a reduction in adiposity after four weeks. Plasma levels of leptin increased in the SD groups, and hyperleptinemia was reduced by training on a treadmill exercise only for four weeks. Insulin levels were not altered, with reduction of hormone for the TTD group subjected to exercise on a treadmill for four weeks. NEFAs levels showed no differences and the improvement in ability to perform the work in animals were observed from four weeks of training on a treadmill exercise. The gene expression showed a different standard when comparing the two periods of training. There was an increased expression of Leptin in the retroperitoneal AT of the SD group, which was blocked by the combination of diet and training on a treadmill exercise. A similar effect was observed in the expressionof Ucp2 in the retroperitoneal AT. There was an increase in the expression of Ucp1 and Adrb3 in BAT. The data analysis presented above suggests that the proposed model leads to obesity from five weeks of diet and the ability to perform work is increased by training on a treadmill exercise from four weeks. Moreover, the metabolic changes influenced by exercise that are not maintained after eight weeks of training on a treadmill exercise, suggesting an adaptation of the animals to the proposed challenge and the establishment of weaker metabolic changes in adipose tissue.


The Apolipoprotein E (APOE)-ε4 genotype is a marker of susceptibility for late-onset Alzheimer's disease (AD). Sleep disturbances may accelerate the aging process and increase the risk for future development of cognitive impairment and dementia. Given that the pathophysiological process of AD can predate its clinical manifestations by years or even decades, the aim of this study was to assess the role of the APOε4 allele on sleep-dependent memory consolidation in cognitively healthy adults.

 16 healthy APOE-ε4 carriers (mean age=49.9±13.7) and 32 healthy non-carriers (age=45.7±12.9) were included in the main analysis. Baseline screening included the Epworth Sleepiness Scale, Morningness-Eveningness scale, Wechsler Adult Intelligence Scale (WAIS) and Beck Depression Inventory (BDI), as well as a baseline polysomnogram (PSG), which also served as an adaptation night. Participants subsequently underwent an overnight testing session, which included computer sessions of the Psychomotor Vigilance Task (PVT) and the declarative Verbal Paired-Associates Task (VPA) in the evening followed by a full night PSG and repeat PVT and VPA sessions in the morning. For further reference, we added an age matched group of 16 non-carriers with newly diagnosed obstructive sleep apnea (OSA, age=48.1±15.1), who underwent the same study procedures.

 APOE-ε4 carriers had higher BDI (p=0.04) and ESS (p=0.01) scores than non-carriers. There were no significant group differences for sleep macrostructure. Evening VPA performance was similar for both groups (p=0.77). The following morning, APOE-ε4 carriers improved by 7.5±6.4 % from the evening before, compared to 13.5±7.0% for the healthy non-carriers (p=0.005). OSA subjects improved by 5.0± 8.1%, which was similar to APOE-ε4 carriers (p=0.34).

 To our knowledge, this is the first study to reveal that healthy APOE-ε4 carriers while showing similar initial learning (encoding) on a declarative memory task compared to healthy controls, exhibit a deficit in sleep-dependent memory consolidation, similar to patients with obstructive sleep apnea. Consequently, this study provides evidence that impaired sleep-related memory processes could be an important harbinger in otherwise healthy individuals, who are at high risk for AD.

 NIH grant # K23HL103850 (Ina Djonlagic) and American Sleep Medicine Foundation grant #54-JF-10 (Ina Djonlagic)


In the paper,it is analyzed the existing problems and elaborated the design methods for Φ322 mm. piercing plug. Moreover,the hollow billets with physical dimension satisfied the requirements are manufactured with the optimization design for physical dimension and shape of piercing plug. As a result,the coefficient of ovality for deformation zone is reduced,the product quality is improved,the frequency of production accidents is reduced as well as the work rate and yield of the production line are improved.


The development of 5G and Software Defined Networking (SDN) are compassed to be singular comprehensive line to allocate massive communication in the future. Conveyance between massive Internet of Everything (IoE) such as machine-to-machine (M2M), vehicle-to-vehicle (V2V), or vehicle-to-infrastructure (V2I) has pressed reseachers to produce fresh or regenerate predecessor framework to collaborate within previous technology aiming toward high-speed connectifity regarding on prerequisites of [1]. Therefore, the contrivance of two popular frameworks, fog computing (FC) and mobile edge computing (MEC) gave more well-knowledges to experts in order to explore extensively about combining on these frameworks and future 5G-based SDN. On this reseach, we will discover about each parameter whose some strengthness and disadvantages on two main research papers from [2] and [3] having explored deeply at these frameworks. In the end, we will suggest concerning of three main component we have discovered, and put references in detail to our statements and whole support inside of them.


Analysis of loading of the high-speed carriage disk brake details with steel and cast iron disks is implemented. A pulsating character of thermal power conducted to the brake disk was taken into account at determination of thermal and stress-strain states. This effect has place in the brakes owing to incomplete overlapping of the disk by a brake shoe. The specified mathematical model of heat exchange under friction, based on solution of non-stationary heat conductiv-ity equation with dominating convection transport of heat, was developed for modeling this phenomenon. The results of modeling make it clear that in the disk surface layers such oscillations of temperature and stresses arise that they must be taken into account at estimation of the brake disk loading. Loading of the disk brake details was evaluated by the levels of maximum arising temperatures and temperature stresses intensities. Maximum values of temperatures and temperature stresses in the cast iron disk at emergency brake application were accordingly 8% and 17% less then in steel disk. The temperature and temperature stresses intensity oscillation range in the cast iron disk accordingly 28% and 17% less then in steel disk.