We used Wiener model to construct power amplifier and Hammerstein model to construct predistortion.A Nonlinear Filtered LMS(NFLMS) algorithm was also proposed based on LMS algorithm and predistortion system model.Based on these algorithms,NFLMS Newton algorithm and improved algorithm for NFLMS Newton are given.The simulation results show that the improved algorithm for NFLMS Newton has faster convergence speed than the NFLMS algorithm,and brings down the algorithm's residual error more quickly.


We evaluated the effects of calcium-entry blockers on parathyroid hormone (PTH) secretion by human parathyroid adenoma cells in vitro. Nifedipine and bamidipine inhibited PTH secretion, while diltiazem had no significant effect. Cytosolic calcium concentrations were measured by use of the calcium-sensitive fluorescent dye fluo-3 with confocal laser scanning microscopy. Nifedipine increased the cytosolic concentration of calcium, whereas diltiazem decreased it. Results suggest that, in parathyroid adenoma cells, regulation of PTH secretion with respect to intracellular calcium concentration would be maintained despite differing response of intracellular calcium concentration following exposure to calcium-entry blockers.


This article highlights some of the similarities between child marriages and child prostitution. Both child marriage and prostitution involve economic transactions, lack of freedom, and the violation of a child's right to consent. This is often exacerbated by social and economic vulnerabilities of children linked to limited life options. In order to capture much of the ongoing discussion and debate taking place in North Africa and the Middle East, this article draws on anecdotal evidence, limited research samples, communication with local actors, and the author's own personal experiences in the region. It also discusses some initiatives undertaken by a range of institutions with the aim of preventing these practices. Willis, Brian M. and Barry S. Levy. 2002. "Child prostitution: global health burden, research needs, and interventions." The Lancet 359(315): 1417-1422. Abstract: ..In this article we estimate morbidity and mortality among prostituted children, and propose research strategies and interventions to mitigate such health consequences. Our estimates underscore the need for health professionals to collaborate with individuals and organizations that provide direct services to prostituted children... ..In this article we estimate morbidity and mortality among prostituted children, and propose research strategies and interventions to mitigate such health consequences. Our estimates underscore the need for health professionals to collaborate with individuals and organizations that provide direct services to prostituted children... Female Gential Mutilation Althaus, Frances A. 1997. "Female Circumcision: Rite of Passage Or Violation of Rights?" International Family Planning Perspectives 23(3): 130-133. Wood, Alexi Nicole. 2001. "A cultural rite of passage or a form of torture: Female genital mutilation from an international law perspective." Hastings Women's Law Journal 12: 347. Abstract: This article adds to the growing literature on FGM by analyzing FGM as a violation of international law, especially the United Nations ban on torture. Section II explores the various types of FGM that are performed, their historical background, the reality of FGM and the various attempts that have been made to help reduce the numbers of procedures performed. Section III examines how international law, covenants and treaties can be used to help protect women from FGM, and also from experiencing the continued agony and repression that accompanies FGM. Finally, this Article concludes by providing proposals for change. Centre for Human Rights. 1995. Harmful traditional practices affecting the health of women and children. Geneva, Switzerland; New York. This article adds to the growing literature on FGM by analyzing FGM as a violation of international law, especially the United Nations ban on torture. Section II explores the various types of FGM that are performed, their historical background, the reality of FGM and the various attempts that have been made to help reduce the numbers of procedures performed. Section III examines how international law, covenants and treaties can be used to help protect women from FGM, and also from experiencing the continued agony and repression that accompanies FGM. Finally, this Article concludes by providing proposals for change. Centre for Human Rights. 1995. Harmful traditional practices affecting the health of women and children. Geneva, Switzerland; New York. R E V I E W D I G E S T : H U M A N R I G H T S & H E A L T H 62 This fact sheet identifies and analyses the background causes of harmful traditional practices, and their consequences for the health of women and the girl child. It also reviews the action taken by United Nations organs and agencies, governments and NGOs to this end. Cisse, Bernadette Passade. 1997. "International Law Sources Applicable to Female Genital Mutilation: A Guide to Adjudicators of Refugee Claims Based on a Fear of Female Genital Mutilation." Columbia Journal of Transnational Law 35: 429. Abstract: This Comment identifies the factors that U.S. adjudicators should take into account when adjudicating asylum claims by individuals n1 that involve the traditional practice of female genital mutilation (FGM) or what has variously been called excision, female circumcision, or female genital surgery. This Comment discusses the practice of FGM, canvasses international human rights principles applicable to FGM and analyzes refugee status determination, including international protection principles associated with the cessation and exclusion clauses of the 1951 Convention relating to the Status of Refugees. A primary focus of this Comment is on the international protection guidelines issued by the Office of the UNHCR. Cook, R.J.; B.M. Dickens; and M.F. Fathalla. 2002. "Female genital cutting (mutilation/circumcision): ethical and legal dimensions." International Journal of Gynecology and Obstetrics 79(3): 281-287. This Comment identifies the factors that U.S. adjudicators should take into account when adjudicating asylum claims by individuals n1 that involve the traditional practice of female genital mutilation (FGM) or what has variously been called excision, female circumcision, or female genital surgery. This Comment discusses the practice of FGM, canvasses international human rights principles applicable to FGM and analyzes refugee status determination, including international protection principles associated with the cessation and exclusion clauses of the 1951 Convention relating to the Status of Refugees. A primary focus of this Comment is on the international protection guidelines issued by the Office of the UNHCR. Cook, R.J.; B.M. Dickens; and M.F. Fathalla. 2002. "Female genital cutting (mutilation/circumcision): ethical and legal dimensions." International Journal of Gynecology and Obstetrics 79(3): 281-287. Davar, Binaifer A. 1997. "Women: Female Genital Mutilation." Texas Journal of Women & the Law 6: 257. Gruenbaum, Ellen. 2000. The Female Circumcision Controversy: An Anthropological Perspective, University of Pennsylvania Press. Gunning, Isabelle R. 1999. "A Global Feminism at the Local Level: Criminal and Asylum Laws Regarding Female Genital Surgeries." The Journal of Gender, Race & Justice 3: 45. Abstract: This essay is one example of a Critical Race Feminist/Critical Race Theorist exploration of the impact of the implementation of international "law" or norms through domestic legislation on women of color at the local level. In the U.S. inconsistencies and hypocrisies are two aspects of the array of reverberations that have been generated by the implementation of the global norm opposing female genital surgeries (FGS) in domestic laws. I will explore these tensions and contradictions in the context of two types of American domestic laws that involve female genital surgeries. Hughes, Karen. 1995. "The Criminalization of Female Genital Mutilation in the United States. " Journal of Law and Policy 4: 321. This essay is one example of a Critical Race Feminist/Critical Race Theorist exploration of the impact of the implementation of international "law" or norms through domestic legislation on women of color at the local level. In the U.S. inconsistencies and hypocrisies are two aspects of the array of reverberations that have been generated by the implementation of the global norm opposing female genital surgeries (FGS) in domestic laws. I will explore these tensions and contradictions in the context of two types of American domestic laws that involve female genital surgeries. Hughes, Karen. 1995. "The Criminalization of Female Genital Mutilation in the United States. " Journal of Law and Policy 4: 321. Abstract: This Note proposes that Congress enact legislation to prohibit the practice of FGM in the United States. Part I describes the origins of and continuing justifications advanced for the practice of FGM, as well as the history of FGM in the US. Part II summarizes the criminalization and treatment of FGM in other Western and African countries. Part III analyzes constitutional and legal issues involved in passing federal legislation criminalizing FGM. Section A argues that Congress has the power to enact federal legislation to prohibit FGM via the Commerce Clause. Sections B and C argue that a federal law prohibiting FGM would not violate the Free Exercise of Religion Clause of the First Amendment or the fundamental right to privacy recognized by the Supreme Court. Section D reasons that if FGM is criminalized in the US, immigrants who practice FGM This Note proposes that Congress enact legislation to prohibit the practice of FGM in the United States. Part I describes the origins of and continuing justifications advanced for the practice of FGM, as well as the history of FGM in the US. Part II summarizes the criminalization and treatment of FGM in other Western and African countries. Part III analyzes constitutional and legal issues involved in passing federal legislation criminalizing FGM. Section A argues that Congress has the power to enact federal legislation to prohibit FGM via the Commerce Clause. Sections B and C argue that a federal law prohibiting FGM would not violate the Free Exercise of Religion Clause of the First Amendment or the fundamental right to privacy recognized by the Supreme Court. Section D reasons that if FGM is criminalized in the US, immigrants who practice FGM H U M A N R I G H T S & H U M A N W E L F A R E 63 should not be exempt from prosecution under a cultural defense or religious exemption. Lastly, Section E analyzes the Federal Prohibition of FGM Act of 1995, authored by Congresswoman Patricia Schroeder, which would make the practice of FGM a federal crime and suggests modification to the proposed bill. Kelson, Gregory A. 1995. "Granting Political Asylum to Potential Victims of Female Circumcision. " Michigan Journal of Gender & Law 3: 257. Abstract: Part I of this article examines two cases. In one case, a U.S. immigratio


Following decertification of the ubiquitous and simple Department of Transpsortaion (DOT) 6M specification package, radioactive materials package Shippers have been faced with the need to use Certified Type B packagings. Many Department of Energy (DOE), commercial and academic programs have a need to ship small masses of radioactive material, where the identity of the material or radionuclides is know but the individual activity of some may not be known. For quantities which are small enough to be fissile exempt and have adequate shielding to ensure low radiation levels, these materials could be transported in a package which provides the required containment level. Because their Chalfant type containment vessels meet the American National Standards Institute (ANSI) N14.5 definition for leak-tight (≤ 1×10−7 ref cm3 air/sec), the 9975, 9977, and 9978 are capable of transporting contents requiring the highest standard of containment. The issues associated with certification of a high-integrity, general purpose package for shipping small quantities of such radioactive material are discussed and the logical basis for certification for such contents is described.Copyright © 2010 by ASME


In this work performed in the Laboratory of Sanitation of Sao Carlos Engineering School- University of Sao Paulo, the results obtained from the operation of a laboratory scale anaerobic fluidized bed reactor are presented for the treatment of a synthetic wastewater with a mean COD of 557 and 700 mg/l during the two phases in which the reactor was studied. In the first phase (Phase A) the mean hydraulic residence time (![Graphic][1] ) was maintained at 1.0 h and in the second phase (Phase B), 1.5 h. The duration of each phase, counted from the initial startup period, was 197 days and 108 days, respectively. The reactor was constructed using an acrylic tube of 1.50 m height and a total volume of 10.5 1. The support material consisted of sand with the grains retained between sieves with openings of 0.210 mm and 0.149 mm. The total height of the fluidized bed was maintained at 1.40 m throughout the experiment. The reactor was operated at ambient temperature (13°C to 31°C), and was fed with synthetic wastewater composed mainly of bovine liver extract, glucose, sodium bicarbonate and ammonium acetate. The results of physical and chemical analyses: pH, alkalinity, temperature, volatile acids, COD, nitrogen and phosphorus are presented. An evaluation was also made during the experiment of the thickness of the biofilm gathered on the sand grains collected over the whole height of the reactor. The mean efficiency of COD removal attained was 62% for the first phase and 71% for the second phase.

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---------------------------------------------------------------------***--------------------------------------------------------------------Abstract In the last few years, the digital data, such images, audio, video and files are exploding. A lot of problems in storage and performance are appearing. Lots of money is spent on these problems. Until the scientists focus on the problems and the needs to solve these problems. Now days there are many techniques used for eliminating the redundant data in the storage. One of the best technique is the deduplication data. In this paper a study on previous researches will do. Focus on the gaps and the problems that they could not solve it or introduce them as a future work. Finally, we propose a new method depending on the literature to fill the gaps. This method based on the checking the data, whether it is in the cloud storage before storing it.


Mycorrhizal fungi are important partners of orchids because they establish close symbiotic relationships with this group of plants, and its preservation is also important for the successful conservation of orchids. In the present study, the conservation of Ceratobasidium sp., a fungal symbiont, using encapsulation in alginate beads was tested over different times, temperatures of storage and dehydrated conditions. Osmotically dehydrated and air-dried beads were stored at room temperature (20 ± 2°C), 4°C, -20°C and - 80°C. The fungal growth was verified after 4, 8, 26 and 96 weeks. A second test was carried out to evaluate the encapsulations of fungi as a form of inoculation in Trichoceros antennifer orchid to promote symbiosis and plants development. The results show that the encapsulation of Ceratobasidium in alginate beads is a viable strategy for its conservation, the beads are of easy manipulation and promote plant growth when inoculated in plant substrate. These results may be adopted as part of effective conservation strategies for mycorrhizal fungi and orchids.


Abstract Currently, obtaining energy from renewable sources, as never before, it has become one of the most important areas, but at the same time challenges in human activities. This is the effect of many factors simultaneously, including because of the media trumpeted the greenhouse effect, the necessity of reducing CO2 emissions, shrinking natural resources, and thus the desire to protect their welfare including conservation (including natural resources) for future generations. The paper presents the results of preliminary numerical analyzes of work for vertical axis wind turbines equipped with air guides. The carried out analyzes indicate the potential possibility of using this type of construction in practice. The obtained power factor value is higher than in classic wind turbines with a vertical axis. The conducted analyzes also indicate the possibility of optimizing the proposed constructional solution in order to increase efficiency of obtaining energy from the wind.


In this study, we compared three domains of social cognition (emotion processing, mentalization, and attribution bias) to clinical and computational language measures in 63 participants with schizophrenia spectrum disorders. Based on the active inference model for discourse, we hypothesized that emotion processing and mentalization, but not attribution bias, would be related to language disturbances. Clinical ratings for speech disturbance assessed disorganized and underproductive dimensions. Computational features included speech graph metrics, use of modal verbs, use of first-person pronouns, cosine similarity of adjacent utterances, and measures of sentiment; these were represented by four principal components characterizing content-rich speech, insular speech, local coherence, and affirmative speech. We found that higher clinical ratings for disorganized speech predicted greater impairments in both emotion processing and mentalization, and that these relationships remained significant when accounting for demographic variables, overall psychosis symptoms, and verbal ability. Similarly, computational features reflecting insular speech also consistently predicted greater impairment in emotion processing. There were notable trends for underproductive speech and decreased content-rich speech predicting mentalization ability. Exploratory longitudinal analyses in a small subset of participants (n=17) found that improvements in both emotion processing and mentalization were predicted by improvements in disorganized speech. Attribution bias did not demonstrate strong relationships with language measures. Altogether, our findings are consistent with the active inference model of discourse and suggest greater emphasis on treatments that target social cognitive and language systems.


Multi Level Marketing or better known as MLM is a form of marketing concept which involves the appointment of individuals to market products or services through direct selling to other individuals in return for commission earned for every completed sale. It does not require a huge capital nor outlet or even a business centre for an individual to be
involved in this kind of business. Hard work and good conmiunication skills are all it takes for an individual to have a large customer base


The kinetics of reversible nucleophilic thiolate ion (RS - with R=n-Bu, HOCH 2 CH 2 , MeO 2 CCH 2 CH 2 and MeO 2 CCH 2 ) addition to Z-substituded β-nitrostyrenes (Z=4-Me 2 N, 4-MeO, 4-MeS, H, 3-Cl, 4-Cl, 3-CN, 4-CN, and 3-NO 2 ), to form ArCH(RS)CH=NO 2 - , have been measured in water at 20 o C. Rate constants in the forward (k 1 ) and reverse direction (k -1 ) and equilibrium constants (K 1 ) correlate reasonably well with Hammet σ-constants for the non-π-donor substituents but show deviations for the π-donors 4-Me 2 N, 4-MeO, and 4-MeS


It is shown that certain unitary gauge operations that are normally of negligible importance in the theory of laser-atom interactions become significant for pulses containing only a few cycles, and it is discussed how to make gauge invariant predictions in general, and in particular in the velocity and length gauges, and in the Henneberger frame.


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With Gov. Arnold Schwarzenegger's (R-CA) signature on September 29, California became the first U.S. state to approve two laws that will move its regulatory scheme toward a comprehensive chemicals policy. The legislation is intended to improve public and environmental health protection and encourage green chemistry-the design of chemical products and processes that reduce or eliminate the use or generation of hazardous substances. A broad coalition of business and environmental groups, including the Chemical Industry Council of California (CICC) and the Environmental Defense Fund (EDF), praised both laws and the process. But other experts say that these first steps fall short of establishing a green chemistry program. Paul Anastas, director of the Center for Green Chemistry and Green Engineering at Yale University and former member of California's Green Chemistry Initiative Science Advisory Panel, criticizes the new laws. "The panel emphasized the need to support research and development of safe chemical products and processes, to support green chemistry education, and to provide incentives for industries to rework existing processes," he says. "These recommendations are not included in the new laws." The laws do not incorporate the comprehensive approach adopted last year by the EU. The sweeping Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) program puts the onus on companies to provide data proving that their products are safe for particular uses. No program similar to REACH exists in the U.S.; the law designed to regulate chemicals, the Toxic Substances Control Act has numerous shortcomings.


PURPOSE: A crystallizing reactor for collecting resources is provided to increase the reaction speed and efficiency of crystallization by injecting crystallizing members, a crystallizing reagent, and a pH adjusting agent. CONSTITUTION: A crystallizing reactor for collecting resources includes a driving part, stirring stirrers(14, 15, 16), a crystallizing reagent injecting hole, a treated liquid discharging hole, a settling inducing and separating member(42), a crystallizing reactor(11), crystallizing nucleus injecting holes(27, 28, 29), and a crystallizing member storing tank(39). Crystallizing members, which are settled at the lower side of the crystallizing reactor, are fed-back to be injected through the crystallizing nucleus injecting holes. A pH adjusting agent is injected through a pH adjusting agent hole to accelerate the crystallization of treating water or effluent. A crystallizing reagent is injected through the crystallizing reagent injecting hole. The crystallizing reagent is one or more selected from magnesium, potassium, calcium, zinc, calcium carbonate, phosphoric acid, iron salt, lanthanum, and ammonium.


Wear resistance of composite restorative materials has been a major concern especially when used as a posterior restorative material. The purpose of this study was to evaluate and compare the wear resistance of novel composites materials by three body wear simulation method. The four posterior composites evaluated in the study were categorized as, group 1filtekz 350, group 2 tetricevoceram group-3 filtek z250, group 4 surefil. The wear instrumentation used was a Dry abrasion tester, customized with stainless steel wheel, and distilled water was used as lubricant. The initial weight of each specimen was measured in milligrams using a highly sensitive physical balance. Material wear was measured by the loss of material at every 5000 cycles from 5000 cycles till 30000cycles. The wear pattern was analyzed with scanning electron microscope. One-Way ANOVA followed by TUCKEYS post hoc test was used for statistical analysis at the 0.05 significance level The mean weight loss values at the end of 30000 cycle was found to be highest in group 3 and weight loss values was found to be lowest in group1 and these findings were confirmed by scanning electron microscope findings


duce a scholarly work stating the full facts of reality as they exist in the world of Catholic education today-an educator who does not find change perplexing and hard to endure but who believes it to be stimulating and challenging and an opportunity for growth and development. When all is said and done, the best that can be said about Catholic Education in a Changing World is that Dr. Schuster fulfilled his commitment to write a book at the conclusion of the Notre Dame study. The long and tortuous road from Trent to Vatican II which he encourages the layman to commence walking is indeed a long and tortuous road for Dr. Schuster. Too bad he presumes that it is long and tortuous for all.


The paper proposes a numerical scheme which makes it possible to calculate the electromagnetic signals in airborne electrical survey problems for the complex form of the current impulse and follow currents in the transmitter loop. In order to calculate the electromagnetic field, the finite element method is used. For taking into account the time-depending current, the "convolution" procedure, which is based on the piecewise constant approximation of the current function and field calculation for the current in the form of the Heaviside function, is used. The problem related to the error of this approximation, in the case when the transmitter loop is located at some altitude above the Earth surface, is discussed. The results of verifying the proposed computational scheme, comparative analysis of computational costs and analysis of the follow current effect are presented. The results of the numerical experiments show that, on the one hand, when the modeling of the airborne electromagnetic signals is performed, it is necessary to take into account the current form (including the follow current), but, on the other hand, this can be performed most accurately and with low costs by the approach proposed in this paper.


Etravirine (1) is a novel diarylpyrimidine non-nucleoside reverse transcriptase inhibitor and has recently been approved by the U.S. Federal Drug Administsration for the treatment of AIDS. Its reported synthesis is fraught with many difficulties, the foremost being the poor yield and long reaction time required at the aminolysis stage. We attributed this problem to the presence of a bromide group adjacent to the reaction site of the advance intermediate (6). In order to circumvent this issue, we proposed to defer the installation of the bromide group at a later stage, preferably after aminolysis. Indeed, this protocol has worked well. However, in the process of installation of diarylether and diarylamine functionalities at appropriate positions, we had to reverse the sequence of displacement reactions of the dichloride intermediate (9) with 3,5-dimethyl-4-hydroxybenzonitrile (5) and 4-aminobenzonitrile (3). The classical bromination led to the completion of etravirine synthesis.


The technological revolution brought by the internet, high performance computing, and artificial intelligence has fundamentally changed and continues to alter the landscape of finance. These innovations, if used with a malicious intent, can seriously destabilize the financial market. For this reason, counter-measures in the form of new detection methods are needed. In this study, we propose a novel detection framework that uses a model of fraudulent behavior to detect fraud from observed data. A similarity measure is defined to decide if the recorded actions of a monitored trader are matching actions of the fraudulent agent. We illustrate the framework on a simple form of manipulative trading in a simulation environment of a market consisting of two exchanges. This demonstrative case study is inspired by a price manipulation scheme that occurred on the Bitcoin market in 2017/18, where such simple forms of manipulation were observed. Simulation results outline vulnerabilities in markets, where uneven distribution of liquidity is present, as this can be exploited by pump-and-dump scheme.


The invention discloses a super capacitor charger based on the STM 32F407IG. The super capacitor charger is composed of a power source, a buck main circuit, a drive circuit, an ARM, a protection circuit, an amplification circuit and a sampling filter circuit. An adopted buck voltage reduction chopper circuit is composed of direct current power source input, an MOSFET, a diode D1, an inductor L1 and a capacitor C1. The buck main circuit is connected with and charges a supercapacitor. The drive circuit is connected with the buck main circuit to form the chopper circuit. The ARM is connected with the supercapacitor through the protection circuit, is connected with the drive circuit and outputs signals to control the drive circuit. The buck main circuit feeds back signals to the ARM by being connected with the sampling filter circuit. The sampling filter circuit is connected with the amplification circuit, and the amplification circuit is connected with the ARM. According to the super capacitor charger based on the STM 32F407IG, the STM 32F407IG serves as the control core, PWM output is achieved, the MOSFET is driven by the TLP 521, the hardware circuit can be simplified, and control accuracy can be improved.


Physical properties of β- A x V 2 O 5 ( A = Na, Ag) have been systematically reconsidered from structural, electric, and magnetic points of view. We prepared samples, both powder and single crystal, with precise composition for this purpose. The single crystals have been successfully grown by a self flux method using NaV 3 O 8 as a flux. The precise adjustment of x was performed by embedding the as-grown crystals in a large amount of powder and heating them. β-Na 0.33 V 2 O 5 was not a conventional semiconductor but a possible anisotropic metal at higher temperatures. It exhibited a metal-insulator transition at 136 K, suggesting a charge ordering. The ordered structure underwent a magnetic ordering with T c = 24 K. We also observed a development of 1×2×1 superstructure below 230 K, suggesting an ordering of the intercalated ion. Those transitions similarly occurred in β-Ag 0.33 V 2 O 5 . The deviation from x = 0.33 drastically decreased the transition temperatures or magnitudes of anomalies at the transi...


To understand the relation between the geometric design of optically long tunnels and visibility of the exit area, in this study oculomotor (eye movement) data are collected from several drivers in Yunnan Province, China, and drivers' fixation rate and saccade amplitude in the visible zone of the tunnel are measured as key indicators. The driver's visual recognition is analyzed and key elements in the optimal design of the exit points of optically long tunnels are discussed. The results show that visual recognition is closely associated with the radius of the road curvature: as the radius of curve decreases, the visual focus is gradually attracted to the inner side of the curve, the proportion of small-angle saccade increases, and the dispersion of the saccade amplitude decreases.


More and more, adult learners are finding the convenience and flexibility of online learning a match for their learning goals and busy lifestyles. Online degree programs, courses, and virtual universities targeting adult learners have proliferated in the past decade. Although students can easily locate an online course or degree program that's both convenient and accessible, they may face significant challenges in developing a new set of skills for this type of instruction. Educators have speculated on the development of student skills necessary to succeed in online learning, but relatively few publications cover the topic from the perspective of successful online students. I developed the study summarized here to provide this perspective and to identify useful strategies that instructors can promote in their online courses.


Vigilance tasks, from driving a vehicle to surveillance to security monitoring, are both commonplace and high-stakes. Yet users have well known difficulties sustaining vigilance. We evaluate the ability of an augmented cognition closed-loop attention management (CLAM) system to sustain vigilance and task performance by monitoring operator's psychophysiology, detecting inattention, and activating a countermeasure when inattention crosses a threshold. Eighteen participants performed a vigilance task and were monitored for inattention via a combination of eye, head, and electroecephalographic (EEG) measures. A cognitively demanding secondary task was activated either when inattention was detected or randomly throughout a 40 minute session. While participants in both conditions demonstrated a vigilance decrement, as measured by an increase in misses over the course of the session, the CLAM condition produced 17% fewer misses overall than the random condition. This improvement was not due to the countermeasure, per se, but to the timing of the countermeasure to participant's detected inattention. The advantage for a tailored presentation of the secondary task is noteworthy because prior evaluations of continuous secondary tasks demonstrated degraded vigilance performance. The results inform our understanding of how human vigilance operates and the technology for its detection and manipulation.


The invention provides a preparation method of citrate. The method comprises the following step of: undergoing a contact reaction on citric acid and monohydric alcohol in the presence of a catalyst to obtain citrate, wherein the citric acid is citric acid containing one or more of Fe , Al and Cu prepared with at least one of the following methods: in a method I, a clear citric acid zymotic fluid is separated and purified with a calcium salt method to obtain the citric acid containing one or more of Fe , Al and Cu ; and in a method II, a clear citric acid zymotic fluid is separated and purified with a chromatography to obtain the citric acid containing one or more of Fe , Al and Cu . By adopting the method disclosed by the invention for preparing the citric acid, the procedure can be simplified, the dosage of a catalyst can be reduced, and the yield and purity of the citrate are increased.


Objective To study the role of ASTRAL score in predicting the prognosis of anterior and posterior circulation acute cerebral infarction(ACI).Methods Six hundred and ninety-two ACI patients were divided into anterior circulation ACI group(n=481)and posterior circulation ACI group(n=211)according to their head MRI.Patients were assessed with a ASTRAL score within 24 hours after admission.The outcome of the 30 day of onset was the end of the study.Good prognosis was defined when the mRS score was 0-2and poor prognosis was defined when the mRS score was 3-5.The role of ASTRAL score in predicting the prognosis of anterior and posterior circulation ACI was analyzed according to its ROC curve.Results There were 81 anterior circulation patients with poor prognosis,and there were 44 posterior circulation infarction patients with poor prognosis.The ASTRAL score was lower in ACI patients with a good prognosis than in those with a poor prognosis(17.30±3.66 vs 26.81±7.90,17.25±4.11 vs 23.66±7.28,P0.01).The rate of poor prognosis increased with the increasing ASTRAL score.The area under the ROC curve for ASTRAL was 0.902 and 0.788 respectively.The best cut-off points was 22 and 19respectively.The sensitivity of anterior circulation and posterior circulation infarction was79.0% and 72.7% respectively,and the specificity was 88.2% and 68.9% respectively.Conclusion ASTRAL score can predict the poor prognosis of ACI patients.


The efficacy and safety of pioglitazone in combination with insulin in type 2 diabetic patient were evaluated. CENTRAL, MEDLINE, EMBASE, CBM, CNKI(up to September 2014)were searched by computer. The quality of included randomized controlled trials(RCTs)was assessed according to the Cochrane Collaboration system review, and then meta-analysis was performed using Stata 12.0. A total of 9 RCTs were included. The results of meta-analyses showed that HbA1C value was lower in the group taking pioglitazone plus insulin than in the group taking insulin without pioglitazone[standard mean difference -0.48, 95%CI(-0.55, -0.40), I2=0.0%, P=0.531], but there were more patients with hypoglycaemic in the pioglitazone plus insulin groups than with insulin without pioglitazone[relative risk 1.33, 95%CI(1.21, 1.46), I2=75.4%, P=0.00].

Key words:
Pioglitazone; Diabetes mellitus, type 2; Meta-analysis; Systematic review; Randomized controlled trial


When the sum of the missing days of a missing child is up to the statutor deadline,as China's basic national policy of family planning,legislature should take their parents' right of re-birth seriously.If their parents,birth is legal,after carrying out a series of strict procedures,their parents can be re-birth.


Uniform equiconvergence of spectral expansions related to the second-order differential operators with involution: −u′′(−x) and −u′′(−x) + q(x)u(x) with the initial data u(−1) = 0, u′(−1) = 0 is obtained. Starting with the spectral analysis of the unperturbed operator, the estimates of the Green's functions are established and then applied via the contour integrating approach to the spectral expansions. As a corollary, it is proved that the root functions of the perturbed operator form the basis in L2(−1, 1) for any complex-valued coefficient q(x) ∈ L2(−1, 1).


Despite many shipwrecks containing oil there is a paucity of studies investigating their impact on surrounding environments. This study evaluates any potential effect the World War II shipwreck HMS Royal Oak is having on surrounding benthic sediments in Scapa Flow, Scotland. HMS (Her Majesty's Ship) Royal Oak sank in 1939, subsequently leaked oil in the 1960s and 1990s, and is estimated to still hold 697 tonnes of fuel oil. In this study, sediments were analysed, over a 17.5 cm depth profile, along a 50–950 m cruciform transect away from the shipwreck. Analysis of polycyclic aromatic hydrocarbons (PAHs) revealed low concentrations (205.91 ± 50.15 μg kg–1 of dry sediment), which did not significantly differ with either distance from the shipwreck or sediment depth. PAH concentrations were well below the effects-range low (ERL) for the OSPAR (Oslo/Paris convention for the Protection of the Marine Environment of the North-East Atlantic) maritime area. The average Pyrogenic Index, in sediments around HMS Royal Oak, was 1.06 (±0.34), indicating PAHs were pyrogenic rather than petrogenic. Moreover, analysis of sediment microbiomes revealed no significant differences in bacterial community structure with distance from the shipwreck, with extremely low levels of obligate hydrocarbonoclastic bacteria (OHCB; 0.21% ± 0.54%). Both lines of evidence suggest that sampled sediments are not currently being impacted by petrogenic hydrocarbons and show no long-term impact by previous oil-spills from HMS Royal Oak.


Abstract : The report deals with the design of a Foa Energy Separator for use in a supersonic aircraft, the LTV F-8U Crusader. Calculations are carried out to obtain a range of exit nozzle area ratios compatible with a variety of operating conditions. The effects of variations of the peripheral rotor velocity and discharge pressures on both the hot and cold outputs are analyzed. The potential merit of using a heat exchanger in conjunction with the separator, or of using ram air rather than bleed air, is also discussed.


Since the development of COVID 19 vaccines, more than 300 million people have been immunized worldwide. Soon after vaccinations were initiated, reports on cases of myocarditis following the second vaccine dose have emerged.This study aims to report our experience with nine patients with post COVID-19 vaccine myocarditis, and to compare them to a cohort of patients who presented with paediatric inflammatory multisystem syndrome (PIMS / PIMS-TS) post COVID 19 infection.We collected all reported cases of patients who developed myocarditis following COVID 19 vaccination (Pfizer mRNA BNT162b2), from all pediatric rheumatology centers in Israel, and compared them to the cohort of patients previously diagnosed with PIMS.Nine patients with myocarditis post-vaccination were identified and compared to 78 patients diagnosed with PIMS. All patients with post-vaccination myocarditis were males who developed symptoms following their second dose of the vaccine. Patients with myocarditis post-vaccination had a shorter duration of stay at the hospital (4.4±1.9 vs. 8.7±4.7 days), less myocardial dysfunction (11.1% vs. 61.5%), and all had excellent outcomes as compared to chronic changes among 9.2% of patients with PIMS.The clinical course of vaccine-associated myocarditis appears favorable, with resolution of symptoms in all the patients in our cohort. The risk–benefit decision for vaccination remains highly favorable, given the potential morbidity of patients with COVID-19, especially those with PIMS.None declared


Physician satisfaction is a critical topic for the medical profession (practicing physicians, physicians in training, or health system administrators), and even for those who sooner or later will interact with a doctor. My intention is to perform a deconstruction of this topic from a sociological perspective, trying to outline the sociological framework in which doctors are performing their jobs today, to define and describe the potential meanings for physician satisfaction and in the end to conclude by responding to the questions: is physician contentment associated with patient care? Is psychological distress related with medical error making? Does physicians? dissatisfaction lower the quality of clinical care?


Sternal wound infections resulting in mediastinitis following coronary artery bypass graft surgery increase morbidity, prolong hospital length of stay, raise hospital costs, and increase both short- and long-term mortality. The increased risk for sternal infections has discouraged the use of bilateral internal thoracic artery grafts, especially in diabetic patients. This chapter reviews the preoperative, intraoperative, and postoperative principles for preventing sternal wound infections and mediastinitis following coronary artery bypass graft surgery.


Nowadays,social transformation is one of the basic elements in China.The communication of the government should focus on two aspects: one is the public relationships,the other is the citizen with civil rights.In fact,the citizen should have been the body of government activities.Therefore,the communication of the government should serve for the citizen.There should be a very effective information syetem and a powerful control of communication.It can be used to develop the communication of government among the social vulnerable group.Besides,we shoule improve the capability of government behavior and maintain the image of the government in order to put forward to the political civilization.


This study attempted to investigate the influence of makeup service factors on customer satisfaction empirically to provide basic data that would help makeup salons enhance customer satisfaction and set a proper direction for services. The results found the following: Among makeup service factors, 'quality of cosmetics,' 'makeup artists' skills,' and 'makeup artists' reputation and kindness' revealed a positive correlation with customer satisfaction with statistical significance. Also, 'makeup artists' reputation and kindness' and 'makeup artists' skills' positively affected customer satisfaction with statistical significance. The results confirm that 'makeup artists' reputation and kindness' and 'makeup artists' skills' have the greatest influence on customer satisfaction. The study results found that customer satisfaction with makeup services could be enhanced by increases in 'reasonable service charge,' 'makeup artists' skills,' and 'makeup artists' reputation and kindness,' thereby increasing revisit rates and making a significant contribution making makeup salons more competitive.


An optimal instrument for the dissection, isolation, vascular coagulation and resection of fat pockets in blepharoplasty surgery must minimize the extent of excessive lateral heat diffusion. Too little heat diffusion during lipoplasty could result in vision-threatening hemorrhage. Too much lateral heat diffusion distorts tissues, thereby interfering with precise and appropriate fat resection. Excessive lateral heat spread increases the degree and duration of postoperative inflammation, thereby prolonging the recovery and increasing the risk of cicatrix formation.


In the central coastal area of Portugal an Environmental Impact Assessment Study of Infrastructures and Farmland Reallocation Project has taken place. The site - Lower Vouga Lagoon System - is a unique man-made landscape that is threatened by various factors, namely salinisation and abandonment. However, it is a place of significant interest for nature conservation. The complexity of the site and of the Project, combined with the significant public attention that surrounded it, called for innovative approaches in terms of methodology and tools for the implementation of the recommendations that at the same time were technically credible and well understood by the public. The Project offered various alternatives and after the Environmental Impact Assessment Study a solution was pointed out. Considering the environmental susceptibility the study pushed forward a set of recommendations towards the sustainability of this landscape that were translated into integrated monitoring plans for water, soil, and biodiversity and landscape diversity.


The empirical analysis shows that business entrepreneurship and innovation entrepreneurship can perfectly increase the growth of Chinese economy.During the period of research,the influence of entrepreneurship on economy is fluctuant,but it has been on a high level since 2001,while the innovation entrepreneurship's contribution is stable but very tiny.


Example 1.1. Let m = 7. The following table shows that the first time a nonzero number mod 7 has a power congruent to 1 varies. While Fermat's little theorem tells us that a6 ≡ 1 mod 7 for a 6≡ 0 mod 7, we see in the table that the exponent 6 can be replaced by a smaller positive exponent for 1, 2, 4, and 6. k 1 2 3 4 5 6 1k mod 7 1 2k mod 7 2 4 1 3k mod 7 3 2 6 4 5 1 4k mod 7 4 2 1 5k mod 7 5 4 6 2 3 1 6k mod 7 6 1 Example 1.2. Since φ(15) = 8, if (a, 15) = 1 then a8 ≡ 1 mod 15. But in fact, as the table below shows, the 8th power is always higher than necessary: the first, second, or fourth power of each number relatively prime to 15 is congruent to 1 mod 15. k 1 2 3 4 1k mod 15 1 2k mod 15 2 4 8 1 4k mod 15 4 1 7k mod 15 7 4 13 1 8k mod 15 8 4 2 1 11k mod 15 11 1 13k mod 15 13 4 7 1 14k mod 15 14 1 Definition 1.3. If (a,m) = 1 then the order of a mod m is the least n ≥ 1 such that an ≡ 1 mod m.


Workers are exposed to a variety of heavy metal pollutants that are released into the environment as a consequence of workplace activities. This chemical pollutants are incorporated into the human by varies of routes entry and can then be stored and distributed in different tissues, consequently have a potential to lead an adverse health effects and/or diseases. As to minimize the impact, a control measures should be taken to avoid these effects and human biological marker is a very effective tool in the assessment of occupational exposure and potential related risk as the results is normally accurate and reproducible. Toenail is the ideal matrix for most common heavy metals due to its reliability and practicality compared to other biological samples as well as it is a non-invasive and this appears as a huge advantage of toenail as a biomarker. This paper reviews studies that measure the heavy metals concentration in toenail as non-invasive matrix which later may adapt in the investigation of metal fume emitted from welding process. The development of new methodology and modern analytical techniques has allowed the use of toenail as non-invasive approach. The presence of a heavy metal in this matrix reflects an exposure but the correlations between heavy metal levels in the toenail must be established to ensure that these levels are related to the total body burden. These findings suggest that further studies on interactions of these heavy metals in metal fumes utilizing toenail biomarker endpoints are highly warranted especially among welders.


Abstract The article describes an experimental analysis devised to determine the responses of a multi-degree-of-freedom non-linear mechanical system to various types and degrees of excitation. Such a system was designed and built to permit analysis in the time, frequency and phase-space domains. The system consisted of six planar pendulums that were coupled by springs having non-linear non-symmetric elastic force characteristics. The free responses showed several internal resonances and thus confirmed the expected behaviour of the system. The embedding procedure was adopted in order to reconstruct the abstract phase space from a single time history. As the main intention of the work is to assess the qualitative difference between linear and non-linear behaviour of a given mechanical system under external harmonic excitation, the increase in the complexity of the system's responses with increasing amplitude of excitation is shown using time-history plots, power spectra, bicoherences, delay-time maps, integrals of correlation dimension and greatest Lyapunov exponents. The bicoherence analysis showed the effect of periodicity on the linear behaviour of the system. By estimating bicoherence it was possible to detect the effect of quadratic phase coupling on non-linear behaviour. The effects of different windows and variations in the number of segments in the averaging process are also shown. Convergence was found in correlation dimension estimates with an increasing embedding dimension when the excitation was harmonic. The correlation dimension was found to increase with an increase of the driving force, thus confirming on increased complexity of the system's responses. The estimated greatest Lyapunov exponents showed the non-chaotic character of dynamics.


A chatbot is an intelligent system which can hold a conversation in real-time with a human being using natural language. This paper describes a multitude of chatbots that communicate in Indian Languages. Extensive research has been done on chatbots in English before, but there is little study on Chatbots in Indian languages. This survey was conducted as a part of our project on an Intelligent Chatbot using Deep Reinforcement Learning. The paper is based on the firm belief that chatbots in Indian languages can be used to bridge the communication gap amongst Indian users. For the chatbot to work resourcefully, it needs to be provided vast logical resources. The peculiarities of natural language require special care, especially in the processing of synonyms, word forms, context, etc. This survey paper deeply studies the methodologies and behaviours of various Indian chatbots, and a comparison is drawn based on their accuracy.


Honey and beeswax production in Zanzibar become important activities in raising livelihood income for rural communities. However, it is still difficult for the production yielded from these to contribute to fighting rural poverty. This research study is geared towards analyzing the performance and efficiency of the honey and beeswax value chain and its challenges in order to disclose opportunities and synergy for reducing income poverty to beekeepers in Zanzibar. The study conducted in Zanzibar focusing both Unguja and Pemba Island, covering two districts from each Island. Descriptive research using both qualitative and quantitative data obtained from primary and secondary sources. Questionnaire was administered to 120 respondents randomly and proportionally selected from beekeepers in four districts. Focus Group Discussions, Key Informant Interviews and Field visits were also conducted. Data were analyzed using Statistical Packages for Social Sciences (SPSS) versions 2016 with Excel Spread Sheet in Office 2016. The result revealed that, the major value chain activities involved were input supply, production, processing, marketing to final consumers. The actors identified were input supplier, producers, processors, traders, and consumers. The study also revealed that, majority 80.4% of beekeepers use traditional/ log hives which proved to give low yield in this study. The result also portrayed that, about 2.8% of respondents that use Langstroth hives whereas 16.0% use top bar hive It was also found that annual average yield of honey per hive types was 9.09litres from traditional/log hive, 10 liters from Top bar hives and 16.85 litres from Langstroth hives. The price of unprocessed honey ranges from TZS 20,000 to 30,000 (9 to 14 US $) per liter while processed honey is T.SH 35,000 to 40,000 (15 to 17 US$) per litre. Various challenges were identified including inadequate supply of modern hive and equipment, climate change and variability, inadequate training and extension services, deforestation and forest fire, inversion of diseases pests and predator, lack of honey processing and marketing centre as well as capital. The profitability analysis indicates that, the annual net revenue per hive is TZS 203,347(US$ 93) for traditional /log hive, TZS 227,166 (US$ 103) for Top bar hive and TZS 342,536 (US$ 156) for Langstroth hive.


We developed a three-dimensional unstructured grid coastal and estuarine circulation model, named the General Ocean Model (GOM). Combining the finite volume and finite difference methods, GOM achieved both the exact conservation and computational efficiency. The propagation term was implemented by a semi-implicit numerical scheme, the so-called θ scheme, and the time-explicit Eulerian–Lagrangian method was used to discretize the nonlinear advection term to remove the major limitation of the time step, which appears when solving shallow water equations, by the Courant–Friedrichs–Lewy stability condition. Because the GOM uses orthogonal unstructured computational grids, allowing both triangular and quadrilateral grids, considerable flexibility to resolve complex coastal boundaries is allowed without any transformation of governing equations. The GOM was successfully verified with five analytical solutions, and it was also validated when applied to the Texas coast, showing an overall skill value of 0.951. The verification results showed that the algorithm used in GOM was correctly coded, and it is efficient and robust.


This dissertation contains three research directions. In the first direction, we use rough paths theory to study stochastic differential equations and stochastic partial differential equations. We first study the Taylor expansion for the solutions of differential equations driven by p-rough paths with p > 2. We provide a general convergence theorem and study the rate of convergence of the Taylor expansion. The main result is about the Castell expansion and the tail estimate with exponential decay for the remainder terms of the solutions. Our results apply to differential equations driven by continuous centered Gaussian process with finite 2D ρ−variation and fractional Brownian motion with Hurst parameter H > 1/4. We then give a new and simple method which allows to get a priori bounds on rough partial differential equations. The technique is based on a weak formulation of the equation and a rough version of Gronwall's lemma. The method is presented on a simple linear stochastic heat equation, but might be generalized to a wide number of situations. Qi Feng-University of Connecticut, 2018 In the second direction, we study stochastic analysis on the horizontal paths space of totally geodesic Riemannian foliations. We first develop Malliavin calculus on the horizontal path space, Clark-Ocone formulas, various integration by parts formulas are obtained. Further more, we prove that the horizontal Wiener measure is quasiinvariant with respect to flows generated by suitable tangent processes. Under suitable assumptions, we further prove a log-Sobolev inequality for a natural one-parameter family of infinite-dimensional Ornstein-Uhlenbeck type operators. In particular, we also get the improved log-sobolev inequality and the equivalence of two-sided uniform Ricci curvature bounds to various functional inequalities. We also obtain concentration and tail estimates for the horizontal Brownian motion on the foliations. In the third direction, we study Ricci flow on totally geodesic Riemannian foliations. Under the transverse Ricci flow, we prove two types of differential Harnack inequalities (Li-Yau type) for the positive solutions of the heat equation associated with the time dependent horizontal Laplacian operators. We also get a time dependent version of the generalized curvature dimension inequality. As consequences, we get parabolic Harnack inequalities and heat kernel upper bounds.


Thank you very much for downloading microprocessors and microcomputer development systems. Maybe you have knowledge that, people have look numerous times for their chosen readings like this microprocessors and microcomputer development systems, but end up in malicious downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they cope with some harmful virus inside their laptop.


Micromorphology, XRD analyses and SEM studies of rhizoliths from Late Middle Pleistocene yellowish brown silty fluvial sediments of Yedurwadi reveal that calcium carbonate has a localized source. Silica and calcium carbonate are formed by the plant roots through their metabolic activity creating a favourable microenvironment for the processes of SiO 2 and CaCO 3 precipitation and replacement.


Rheumatoid Arthritis (RA), a chronic inflammatory musculoskeletal disease affecting primarily the peripheral joints may also present with extra-articular manifestations like involvement of exocrine lacrimal glands. Rheumatoid arthritis patients develop ocular dryness due to inflammation of lacrimal gland tissue. Ocular dryness is also a characteristic feature of autonomic dysfunction which greatly affects the quality of life in RA patients.The study was conducted to assess the parasympathetic ocular function among RA patients using schirmer's test and to find out the correlation of parasympathetic ocular dysfunction with age, gender, disease duration and RF factor positivity. This cross sectional study was conducted in a tertiary care hospital among 200 RA patients aged 20-55 years attending Rheumatology clinic. Age matched control group included 100 persons. Ocular parasympathetic autonomic damage was strongly associated to RF,disease duration and female gender. Early detection and treatment of autonomic neuropathy will not only help to reduce the mortality but also certainly improve the quality of life and reduce the sufferings in RA patients.


Objective: Poor feeding behavior in newborn term infants is a cause of concern and often results in sepsis work-up and antibiotic coverage. The objective of this study was to determine the incidence of infants with poor feeding in the first 24 hours of life and to determine the factors associated with duration of antibiotic usage in these infants. Methods: We reviewed the records of 437 term infants admitted to the special care nursery between January 2000 and December 2001. All infants with poor feeding as one of the presenting features were retrospectively identified. Infants whose feedings were held due to underlying problems such as respiratory distress, gastrointestinal obstruction, and congenital anomalies were excluded. Results: In all, 102 of the 437 infants (23%) were admitted to the special care nursery for poor feeding; of these, 64 (63%) had associated signs and symptoms. Among infants who did not improve feeding within 72 hrs, 62% were exposed to maternal analgesia or anesthesia. All infants were assessed for infection irrespective of maternal risk factors for sepsis and given antibiotics. Blood cultures were negative in 101 infants. However, antibiotics were continued in 51 infants for > 72 hours. Abnormal blood cell count and inability to improve feeding behavior influenced the attending physicians to continue antibiotics beyond 72 hours. Conclusions: Our findings indicate that poor feeding is a common problem encountered in term newborn infants and may be due to exposure to maternal analgesia or anesthesia. Neonatologists are not comfortable in discontinuing antibiotics despite negative blood cultures when poor feeding is observed beyond 72 hours.


After more than 14 years dwelling with the challenges of a Social Clinic in Focused Bioenergetics we intend to share our experience with the bioenergetic therapists community. In all those years we have learned much about the difficulties of establishing a line of work suitable to use the bioenergetic approach with troubled people in troubled social environments, in particular those outside of our consumer society. We had to rely more on a progressive approach than on a regressive one in order to bring the analytical process to a successful outcome, consistent with the focused bioenergetics method we adopted. In this process we did not abandon our psychoanalytic-based approach, but humbly adapted our understanding to terms that could be agreed between therapists and clients, establishing what we call the symbolic universe sharing. We were very moved by the theme chosen for the present conference, «The grounded body as a safe place in difficult times", and felt we should attend. This is the first time a conference addressed exactly our difficulty. The new concepts that were developed during this process will be presented.


A two-year study was undertaken to evaluate the feasibility of growth control of Trinexapac-ethyl and Prohexadione-Ca to turfgrass,more particularly,to the growth control of Festuca arundinacea Schreb.The result shows that Trinexapac-ethyl reduced the shoot height of Festuca arundinacea Schreb distinctly when the applying rate was above 0.095 kg/hm~2;while Prohexadione-Ca suppressed the shoot height by 95.2% at a 0.36 kg/hm~2.rate.At the same time,both Trinexapac-ethyl and Prohexadione-Ca reduced the clipping fresh weight of grasses,but did not affect the clipping dry weight.When Trinexapac-ethyl was applied to clipped turf,the taller the stubble was left, the lower the re-growing plant would be.The equitable stubble height is(4~6 cm).Trinexapac-ethyl and Prohexadione-Ca could improve turf quality and reduce the shoot height and subsequently the frequency of clipping.


There is now much evidence for the involvement of deaminase-mediated somatic mutagenesis during cancer
progression. These developments lead us to reappraise the likely impact of AID/APOBEC and ADAR
deaminases in human cancer progression with their expected lesser impact on somatic mutagenesis in mouse
cancer model systems. The findings are important for pre-clinical trials of immune oncology (IO) drugs
activating adaptive immune responses against tumor cells. Our conclusions are consistent with, and
underline, recent recommendations by Decker and colleagues that IO pre-clinical trials should at least
include therapies against spontaneous tumors in dogs. While the AID/APOBEC deaminase specificity
repertoire in dogs is likely to be less than in humans, it will be far greater than in the mouse and thus more
likely to better mimic dysregulated Ig like somatic hypermutation responses during cancer progression in
humans.


Abstract The so-called fallowing/planting problem is an example of a decision-making situation that is potentially sensitive to meteorological information. In this problem, wheat farmers in the drier, western portions of the northern Great Plains must decide each spring whether to plant a crop or to let their land lie fallow. Information that could be used to make this decision includes the soil moisture at planting time and a forecast of growing-season precipitation. A dynamic decision-making model is employed to investigate the economic value of such forecasts in the fallowing/planting situation. Current seasonal-precipitation forecasts issued by the National Weather Service are found to have minimal economic value in this decision-making problem. However, relatively modest improvements in the quality of the forecasts would lead to quite large increases in value, and perfect information would possess considerable value. In addition, forecast value is found to be sensitive to changes in crop price and pr...


Abstract:Recent scholarship on Johann Georg Hamann has tended to focus on his relation to modernity, specifically the Enlightenment. His critique of rationalism, the obscurity of his style, and his pronounced influence on later figures are just several reasons for reconsidering his historical and literary significance. However, his writings also contain rich and relevant philosophical and theological ideas. This article demonstrates the centrality of Hamann's concept of creation for both his critique of rationalism as well as his ideas regarding aesthetics. Hamann understands nature as the book of creation. Human sensuousness, as an emergent feature of nature, indicates an intrinsic relationality underlying nature. By way of the senses, human beings discover themselves to be entangled with God through nature. Reason rejects this relationality when it seeks to purify itself from nature or the senses. In contrast, reason that is oriented to this fundamental relationality recognizes the beauty and friendliness that permeates nature. This recognition is an invitation whereby one is called to perpetuate these aesthetic ideals in the world.


: Good antenatal care links the woman and her family to the formal health system, increases the chance of using a skilled attendant at birth and contributes to good health through the life cycle. Inadequate care during this time breaks a important link in the continuum of care, and affects both women and infants. Keeping this in mind the researcher justified the need to assess the skills of nursing students in antenatal examination. An experimental research approach and pre-experimental static group design were used. The study finding showed that the mean post interventional skills score of nursing students in experimental group was 34.7±10.13 and in control group was 19.33 ±8.55. This difference in the mean post interventional skills was statistically significant at p<0.001 level. It was therefore concluded that after receiving VATP nursing students in experimental group had improved skills on antenatal examination compared to the control group.


Modern distributed systems often allow independent development of their components. Successful evolution of such systems depends on the flexibility of component interfaces. This paper puts forward a framework for defining and implementing interfaces that can independently evolve while preserving backward and forward compatibility. This framework is based on the SOAP data model and remote procedure call representation.


(57) a method for increasing the biocompatibility of silica glass SUMMARY Silicon concentration more than 55%, the composition obtained thereby, and sol - calcium gel derived silica biological activity on glass - quickly phosphate coating It discloses a method of forming.


Through consulting and analyzing a large number of interrelated documents,and utilizing the theoretical knowledge of health administration,the changes of the occupational health services providers in enterprises are illustrated,and also the influence by the system reform and the future trends of the changes.The evidences indicate what is significant changed is not only the model,but also the number of the occupational health services providers in enterprises,and it mainly depends on three correlation factors in system reform including the state-owned enterprise reform,the supervision functions on occupational health being adjusted and transformed,the medical and health system reform and the combined influence.In the face of the severe situation of the nationwide prevention of occupational diseases,the occupational health services providers in enterprises should be brought into the system of occupational disease prevention and control,and be given full play to provide the basic occupational health services.The ability of them should be enhanced and to achieve the purpose o"ftreating before illness".


The impurity blow-off technique is a useful technique for obtaining clear evidence of impurity behaviour in Tokamak plasmas. In this paper, we describe how the blow-off technique is applied to a DIVA plasma and present some experimental results. The metals injected are aluminium and gold. A layer of metal about 0.2 µm thick is adsorbed onto a pyrex glass plate, through which a Q-switched laser beam passes to irradiate the thin film. The film is vaporized by the laser beam and injected into the DIVA plasma with directional velocity. The injection rate is easily and accurately controlled by changing the film thickness and/or the aperture of the laser beam. The total number of aluminium atoms evaporated is 8.0×1016 and their velocity is 5.2×105 cm/s. Thus, the maximum increase in electron density is about 8% and the spectral line signals of Al XI 550 Å are observed with good reproducibility.


edness, Privateness, Apprehension, Openness to Change, Self-Reliance, Perfectionism, and Tension. The Personality Self-Perception Form, a non-standardized, self assessment of personality has medical students rate themselves along a continuum of factors using descriptions of the 16PF factors. This instrument was conceptualized and used in an earlier study. This instrument was developed from the 16PF scores sheet with the permission of the test publishers. For purposes of the present study, permission for use of the PSP was secured by Scott Meit, PsyD as part of a larger, multisite study of personality of medical students. The Career Plan Survey is a brief 13-item survey that asks students to indicate their top three medical specialty choices. Primary care specialties were family medicine, internal medicine, and pediatrics. Non-primary care specialties included all other specialties including dermatology, emergency medicine, pathology, psychiatry, radiology and other specialties including surgery. The Physician Values in Practice Scale (PVIPS) assesses the following six broad values: Prestige, Service, Autonomy, Lifestyle, Management and Scholarly Pursuits. Medical students rate how strongly they agree or disagree with 38 statements. Data Analysis Scores from the 16PF, PSP, PVIPS, and the Career Plan Survey were used to predict students' PC interest or NPC interest using logistic regression analysis. Results About 80% of the medical students were correctly categorized into PC or NPC based on these variables. The strongest noncognitive predictor was Warmth, measured by either the standardized, psychological instrument (16PF) or the non-standardized, self-assessment survey (PSP). Dutifulness (measured by the Rule-Consciousness factor) and Trusting Nature (measured by the Vigilance factor) significantly added to PC prediction, if measured by the 16PF but not the PSP. Placing higher value on service and lower value on prestige were significant predictors only if personality scores (16PF/PSP) were not entered into the analysis (see Table 1). These five non-cognitive variables were significant even after accounting for gender, race, and physician parents. Discussion Identifying students who may pursue primary care specialties is important to medical schools. This study examined personality factors and values to better understand how these non-cognitive qualities describe medical students who express an early interest in primary care specialties from those who do not. Specifically, the findings of this study may be helpful to medical school admissions personnel who review applications, interview, and admit students For example, candidates describing themselves as warm and attentive to others during interviews or in their personal statements may be expressing an accurate selfassessment, because Warmth scores from both self-report and standardized measures similarly predicted PC interest. A previous study using the 16PF revealed that family practitioners scored higher on Warmth than anesthesiologists and general surgeons. Regarding the personality factors that pertain to Dutifulness and Trusting Nature, the 16PF better predicted which students had an interest in primary care compared to the non-standardized PSP. With regard to earlier research using the 16PF, it is interesting to note that Borges and Osmon found that the personality factor of Dutifulness differentiated family practitioners from anesthesiologist and general surgeons. Family practitioners were more dutiful than the other specialists. Additionally, regarding Vigilance, family practitioners were found to be more trusting compared to their non-primary care counterparts. Furthermore, based on the results of this study, the authors recommend the PVIPS, as a personal values measure, be administered independent of the 16PF. The PVIPS scales of Service and Prestige predicted PC interest. Medical students with a primary care interest placed a higher value on service and assigned a lower value to prestige than medical students who were interested in non-primary care specialties. Predictive validity of non-cognitives throughout medical school should be examined. For example, a next step in our research is to survey these students after they select a medical specialty to determine how many students with an early interest in primary care actually entered a primary care specialty. It is suggested that qualitative interviews be conducted to provide added information about specialty selection. References 1. Association of American Medical Colleges. Report I: Learning Objectives for Medical Student Education: Guidelines for Medical Schools. Washington, DC:AAMC;1998. 2. Cattell RB, Cattell AK, Cattell HE. Sixteen Personality Factor Questionnaire. Champaign, IL: Institute for Personality and Ability Testing, Inc.;1993. 3. Anderson-Meit H. Objective and subjective personality characteristics of medical students [dissertation]. Morgantown, WV: West Virginia University; 2001. 4. Hartung PJ. Manual for the physician values in practice scale. Rootstown, OH: Northeastern Ohio Universities College of Medicine; 2004. 5. Hartung PJ, Taber B J, Richard GV. The Physician Values in Practice Scale: Construction and initial validation. J Voc Behav. In press. 6. Borges NJ, Osmon WR. Personality and medical specialty choice: Technique orientation versus people orientation. J Voc Behav. 2001;58:22-35. Table 1. Logistic Regression For Predicting Primary Care Interest using the Physician Values in Practice Scale Predictor Beta S.E. p* Service .101 .042 .021 Prestige -.090 .039 .017 * significance level p < .05


One of the important areas to clarify the Cenozoic volcanic history in southern Kyushu is in the vicinity of Mt. Yaeyama, Kagoshima Prefecture (Fig. 1). The outline of the geology in this area was reported by Taneda et al. (1957), but the stratigraphy was somewhat confused because some pyroclastic flow deposits were cor related incorrectly. Miyachi and Miyachi (1975) studied the geology in this area with special emphasis on pyroclastic flow deposits and constructed a new geologic map and stratigraphic sequence (Table 1). Based on the geologic map, Takai (1981) collected about 400 oriented samples of volcanic rocks and pyroclastic flow deposits in this area, measured their remanent magnetism, and pointed out some incon sistencies with the geologic map. The remanent magnetism of the Iriki pyroxene andesite shows two directions, normal and reverse. The andesite developed on the west side of Ichihino River shows normal magnetisation, but the andesite on the east side shows reverse magnetisation. He concluded that the Iriki pyroxene andesite on the west side and the one on the east side were not produced at the same time. The andesite on the west side was formed in the Gauss normal epoch and the one on the east side was formed in the Matuyama reversed epoch. He also concluded that the andesite on the east side should be included in the group of younger lavas (Table 1). Other inconsistencies between the geologic map and rock paleomagnetism are as follows. The pyroclastic flow deposits in the Inugoyadan area have a normal direc tion of natural remanent magnetisation. Therefore, the pyroclastic flow in this area does not coincide with the direction of pyroclastic flow 2, but with the direction of pyroclastic flow 1. Basalt in the Naka yama area has been correlated with Yae yama basalt 2; however, the magnetisation of the Nakayama basalt is reverse, whereas in the Yaeyama basalt 2 it is normal . Therefore, the basalt in the Nakayama area


Abstract Ylids generated from diphenyl allylic phosphonium salts reacted with aliphatic aldehydes containing a terminal oxygen functionized group in the absence of lithium salt to give E,E-conjugated dienes. The stereoselectivity depends mainly on the base used, the allylic part of phosphonium salts also shows some effect on stereochemistry. Eight conjugated dienic insect sex pheromones and related analogues with different E-selectivities were obtained.


Based upon the publication of the statues approved in 1389 by the General Chapter of the Portuguese branch of the Order of Saint James, the author analyzes the tensions that characterized the internal life of the militia from 1389 to 1434, when the only known copy of those statues were transcribed to the Cartulary of Sesimbra. Even though the statues of 1389 give a good glimpse of the disorders raised by the war with Castile, and especially by the troubled election of the master of the militia, their most interesting feature is the attempt to normalize the personal wealth of the brethren, long before similar rulings were adopted in Castile. It is unclear if they were fully complied by the following masters, as the new rulings were in contradiction with the wording of the Order's rule and with the militia's traditions. On troubling times, having a copy of those statues on the Cartulary of Sesimbra was perhaps a way of trying to safeguard the legitimacy of the acts that were done under its rulings.


Background: Despite the decisive role of nurses in patient's education, they have limited ability to carry out this responsibility. One of the reasons for this incompetence is insufficient nursing education programs. This study aimed to compare and contrast the effects of multiple teaching methods and conventional methods on knowledge, satisfaction, and performance of bachelorette nursing students.


According to a first embodiment, the roller mill according to the invention for the comminution of brittle material for grinding essentially of a) at least said at least one grinding roller is constructed as a loose roller of a grinding roller rotatable about a rotation axis, which cooperates with an opposing surface such that the grinding material is crushed between the grinding roller and the counter surface, b) bearing blocks for supporting the grinding roller, wherein the bearing blocks and horizontally displaceable by a rotational axis intersecting vertical bearing axle is rotatably guided in the machine frame, c) a machine frame supported on the pressing means for urging the grinding roll via the bearing stones with an adjustable grinding pressure, and d) wherein each bearing stone two resilient compensating elements are assigned to compensate for misalignment and / or deflection of the grinding roller, at least, which are arranged between the machine frame and the bearing blocks. The compensation elements are - in plan view of the roll mill - disposed tangentially to a circle around the vertical support shaft or a circular arc formed around the vertical bearing axle.


The subject of the research is to examine the private security preparedness for disasters caused by natural and anthropogenic hazards. In addition, the relationship between preparedness levels and various demographic and socio-economic factors is examined. The survey was anonymous with 4-point Likert scale questions (1I absolutely disagree; 4I absolutely agree). It was conducted at the University of Criminal Investigation and Police Studies in Belgrade, during the initial course for obtaining a private security license and the course for combating domestic violence were attended by members of the police from all over Serbia. Data for the study were collected from a total of 178 members of private security. The research was conducted from April to June 2019. Within the first part of the questionnaire, there were questions concerning demographic and socio-economic characteristics of the respondents (gender, age, education, marital status, working experience, served military status), while the second part contained questions about the p the private security preparedness for disasters caused by natural and anthropogenic hazards (e.g perception of the degree of responsibility due to the type of work performed in case of natural and anthropogenic disasters, perception of the level of preparedness of a private insurance company, knowledge of safety procedures for disaster response, evaluation of the response efficiency of first responders, etc.). The results of the multivariate regressions of preparedness subscale showed that variables (e.g., gender, age, education, marital status) were not significantly affected by preparedness.


The uptake and translocation of 42K deposited on corn leaves (Zea mays L.) decrease significantly when the osmotic potential of culture solutions is lowered to –8.2 atm with polyethylene glycol (PEG 1000), before the application of 42K. The effect of this water stress on the translocation and distribution of 42K was not completely reversible in plants temporarily growing on the solution of smaller osmotic potential. After a 25-h period of recovery on a solution without PEG, there was always a difference between plants either not treated or treated previously with PEG. It appears clearly that the rates of translocation vary directly with the water content of plants.


To meet the demand for tiled rendering 3D graphics,and to quickly output the rendered pixels,it proposed the architecture of tiled raster logic operation.The tile processors operate in parallel.Each processor implements fragment test,blending,logic operations and mask operations.The implementation is able to output four pixels each clock period.The design is simulated on ModelSim and implemented on Xilinx FPGA.The result shows that the design is workable.


On attempting to purify thromboplastin, various investigators1 have obtained mat,erials which possess decreased thromboplastic activity. In our work we have confirmed these observations.2 The question arises as t#o what causes this decrease in tjhromboplastzic act,ivity. Is it that a component inherent to the thromboplastin molecule has been denatured, inactivated, or removed, thus inactivating the molecule? Or is it due to the presence of a.n inhibitor, the concentration of which has been increased by the attempted purification procedure, thus causing a decresse in tzhe observed thromboplast)in a.ctivity? It is our belief that' the reduction in t,hromboplastic activity is due to an increase in concentration of t,hc thromboplastin inhibitor. Chemical isolation and identification of such a substance might indirectly point to the chemical structure of thromboplastin, since it is a known fact that, most, biologically a,ctive compounds ha\vc! a structure similar t,o their inhibibors. We have investigated the possibility of isolating a thromboplastin inhibitor. By chemical fractionation, a material possessing inhibitory properties was obtained from the phosphatide fraction of dried beef brain and rabbit lung thromboplastins, and also from soy bean phosphatides and human pla.sma.3 In our preliminary work our most active inhibitory fraction had chemical properties similar to inositol phosphatides isolated from brain and soy beans. On chemical analysis, t,he following data were obtained: brain inositol phosphat.ide, C 53.3, I' 4.3, K 1.0, ash 17.1; soy bea.n inositol phosphatide, C 54.1, 1' 2.9, N 1.1, ash 13.2. The analytical dat.a compare favorably with the analysis given by Folch4 on brain inositol phosphatide, and by Woolley5 on soy bean inositol phospha,tide. To verify t'he identity of our thromboplastin inhibitor preparation, we t)hen isolat,ed brain and soy bean inositol phosphatides by the methods of Folch4 and Woolley.6 The material isolated in t,his manner had the same properties as our t'hromboplastin inhibitory fraction, indicating that it is identical with the inositol phosphatide fraction. Samples of inositol phosphatide


Reviewed were the problems of obstetrics at different angles science, practice and teaching, based on an overview of modern technologies for reduction of maternal and infant morbidity and mortality, as well as treatment of gynecological diseases. It was shown that treatment of pregnant women from different diseases should be carried out in specialized hospitals from beginning until the end of pregnancy, rather than in obstetrical hospitals. Scientific rationale of modern technologies for the treatment of bleedings has already shown its effect by reducing almost two-fold the role of the bleedings in the structure of the causes of maternal mortality. The medical aspect of the problem lies in the urgent replacement of surgical abortion with a drug-induced one in order to reduce the primary factor of reproductive sickness of the female population of the country. The work of the neonatal services significantly improved with the incorporation in 1987 of the 24-hour neonatologists' shifts, with the increase of their professionalism, the use of surfactant, and respiratory equipment. Creation of a scheme of delivering obstetric and gynecologic care, which for the first time governs the responsibility of municipal authorities, the administration of the hospitals and the doctors themselves, in conjunction with the new sanitary regulations and standards is a progressive step towards improving the health care system in general.


Beam loss monitor(blm) system has been designed in many electron storages in order to indirectly measure lost electrons, which can be used to analysis beam loss mechanism and beam life. It can contribute to beam commissioning and improving stable operation of storage ring. According to lattice structure of the HLS II storage ring, 64 beam loss detectors have been located in the upper, lower, inner, outer side surfaces of vacuum chamber in the HLS II storage ring. Some preliminary researches based on the HLS II blm system have been done. The results in successfully stable operation and unsuccessfully stable operation in beam commissioning stage were compared. Analysis of a sudden lost beam phenomenon were carried out. INTRODUCTION Hefei Light Source II(HLS II) has been upgraded from August 2010 and now enter formal operational phase. It consists of a linac, a transport line and a storage ring. The energy of beam is accelerated to 800MeV when beam reaches the end of the linac and beam is injected into storage ring through the transport line. In order to protect machine, speed up commissioning, conventionally diagnose beam and study beam life, beam loss monitor system is designed for the HLS II storage ring. According to lattice of the HLS II storage ring, beam loss monitors are installed nearby quadrupole magnets[1, 2]. In order to monitor beam loss in different directions of the vacuum chamber, every 16 beam loss monitors are respectively mounted on upper and lower side surfaces of the vacuum chamber in vertical direction and on inner and outer side surfaces of the vacuum chamber in horizontal direction. The layout of beam loss monitors in the HLS II storage ring is shown in Fig. 1. Site installation diagram is shown in Fig. 2. Bergoz's PIN-diode detectors are used as beam loss monitors in the HLS II storage ring. The detector is composed of two PIN-diodes mounted face to face to form a 2channel coincidence detector in which MIPs (minimum ionizing particles) cause ionizations in both PIN-diodes, a coincidence occurs and an output pulse is generated[3]. BLM SYSTEM STRUCTURE Beam loss monitor system structure is as shown in Fig. 3. The generated pulses in four blm detectors located in the upper, lower, inner, outer side surfaces of vacuum chamber are transmitted to Data Acquisition(DAQ) device to shape pulses, count pulses, and transmit results to PC via ethernet. Labview program on PC publishes results in epics environment and any PC via intranet can acquire blm results. Fig. 4 is Labview program main interface for blm. Blm results of four different orientations in each monitoring position display with histogram. Figure 1: The layout of beam loss monitors in the HLS II storage ring. Figure 2: Site installation diagram for beam loss monitors in the HLS II storage ring. Figure 3: Beam loss monitor system structure diagram. ___________________________________________ * Supported by the National Science Foundation of China (11175173, 11375178) # firstname.lastname@example.com MOPMB043 Proceedings of IPAC2016, Busan, Korea ISBN 978-3-95450-147-2 190 C op yr ig ht © 20 16 C C -B Y3. 0 an d by th e re sp ec tiv e au th or s 06 Beam Instrumentation, Controls, Feedback and Operational Aspects T03 Beam Diagnostics and Instrumentation Figure 4: Labview program main interface for blm DAQ device is R&D by National Synchrotron Radiation Laboratory of University of Science and Technology of China and Department of Engineering Physics of Tsinghua University. DAQ device is as shown in Fig. 5. Figure 5: DAQ device for beam loss monitoring PRELIMINARY RESEARCH OF HLS II BLM SYSTEM Preliminary Research On Comissioning Stage In early April 2015 Vacuum leakage at straight section after the fifth bending magnet happened, which leaded to degree of vacuum deteriorated. So vaccum chamber of this place was maintenanced. When the vaccum chamber was reinstall beam couldn't be injected. Beam loss at this time was shown in Fig. 6. As is shown in Fig. 6, beam was mostly lost at injection point (injection point is between No.1 blm and No.16 blm position). The reason may be that injection system exist problems. Additionally, beam totally lost at No.6 blm position and the lost beam at the outer side is more than at the inner side. Thickness of outer wall is more thicker than thickness of inner wall for vacuum chamber, so beam was totally lost at the outer side of No.6 blm position. Possible reason is that orbit at No.6 blm position had lateral side deviation. After adjustment of relevant parameters, distribution pattern of beam loss subtly changed. The result is shown in Fig. 7. It can be concluded that beam arrived No.12 blm position. But beam loss was also lost more seriously at the outer side of No.6 blm position than at the inner side and beam current can't be increased. In April 18 researchers improved the previous problems and beam can pass the entire storage ring nicely. The result is shown in Fig. 8. The beam losses became less at No.15 and No.16 blm position. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 0 1 2 3 4 5 6 7 8 9 10 11


SummaryA 76-year-old man developed a circulating inhibitor against factor V after abdominal surgery, ampicillin and one unit of blood were given. Twelve days after the cholecystectomy a minor bleeding problem was observed. Coagulation screening test indicated the presence of the potent inhibitor. A concomittant antibody with antipcnicillin specificity was confirmed.


Under the background of the digital revolution era, college English teaching and learning are facing tremendous changes. Effective college English learning has long been overwhelmed by the focus on effective teaching in the traditional classroom teaching model. Based on Biggs's 3P Model of Learning, this paper discusses the essential elements in effective MOOC-based college English learning environments, deconstructs and reconstructs college English classroom.


Dry corn stalks were catalytically and uncatalytically thermally decomposed at 300 o C for different retention times (2-6 h). The catalyst employed in the pyrolysis process was Pd-doped -Al2O3. The bio-oils produced were detected and identified using a gas chromatography/mass spectrometry (GC/MS). The results showed that the presence of the catalyst increased the bio-oil yield by approximately 50% relative to the uncatalyzed process. The bio-oils produced were found to contain carboxylic acids, esters, alcohols, phenols, alkanes, guaiacols, multi-component compounds, and miscellaneous oxygenates. Some of the compounds identified were produced in large volumes. The results of this study indicate that low-temperature catalytic pyrolysis of corn stalks is a promising technology for the commercial production of bio-oil and valuable chemical feedstock.


Abstract
Antimicrobial resistance is one of the major global public health problems. There are numerous factors which contribute to the development of antimicrobial resistance. One such factor is integrons which is a mobile genetic element. Integrons contribute to the spread and distribution of antimicrobial resistance genes across diverse bacterial species through horizontal gene transfer. Integrons are made up of three components namely an integrase gene (intI), a primary recombination site (attI) and a promoter region. Integrons transfer resistance genes through transfer of plasmids or through phages. There are two types of integrons such as resistance integrons and super integrons. Resistance integrons are of 4 classes (class I-IV). Class 1 integrons are major contributors of antimicrobial resistance globally and found as contaminant in all ecosystems dominated by humans. The peculiarity of integrons is that they offer a mechanism for quick migration and exchange of various resistance genes. Bacteria with antibiotics, disinfectants and heavy metals discharged into waste streams hotspots are created where intricate interactions and selection events can take place for the interchange of genes and the creation of novel gene combinations.


Probability distribution fitting of an unknown stochastic process is an important preliminary step for any further analysis in science or engineering. However, it requires some background in statistics, prior considerations of the process or phenomenon under study and familiarity with several distributions. As such, this paper presents an alternative approach which doesn't require prior knowledge of statistical methods nor previous assumption on the available data. Instead, using Deep Learning, the best candidate distribution is extracted from the output of a neural network that was previously trained on a large suitable database in order to classify an array of observations into a matching distributional model. We find that our classifier can perform this task comparably to using maximum likelihood estimation with an Anderson-Darling goodness of fit test.


Printing presses were instrumental in creating and upholding a sense of community during the eighteenth century. While the importance of print in the development of colonial America and the nascent United States is well-established, Imprinting Britain extends the historical discussion northward to explore the dynamic and interrelated world of newspapers, coffee houses, and theatre in the British imperial capitals of Halifax and Quebec City. Michael Eamon describes how an English-language colonial community coalesced around the printed word, establishing public spaces for colonists to propose, debate, and define their visions of an ideal society. Whereas American newspapers functioned as incubators of republican and revolutionary thought, their British North American counterparts featured a moderate discourse that rejected republicanism, favoured civic engagement, advocated liberty with propriety, extolled democracy under monarchy, promoted reason over superstition, and encouraged social criticism without revolution. The press also safeguarded against the uncertainties of colonial life by providing a steady stream of transatlantic news, literature, and fashion that helped construct a sense of Britishness in an environment rife with mixed loyalties. Imprinting Britain is the story of communities that turned to the press for a canon of British norms, literary touchstones, and Enlightenment-inspired ideas, which offered a blueprint for colonial growth and a sense of stability in an ever-changing, transatlantic milieu.


This article is devoted to the study of the attractiveness of the Republic of Tatarstan as a site for developing youth potential in a field of innovations. Modern approaches to the spread of scientific knowledge in the field of science and technology gave birth to synergies between the different structures in the development of scientific and technical creativity and successful implementation of the potential of children and youth in the Republic of Tatarstan. It creates the conditions to stimulate the interest of young people to high-tech solutions in the field of innovation of science and technology. The article presents the results of a survey conducted among young people engaged in technical creativity in the territory of the Republic of Tatarstan, practical work aimed at identifying the attractive factors of the Republic of Tatarstan youth, results of a poll helping to determine the level of attractiveness of the region and the main factors of further youth employment at the industrial sites of the Republic of Tatarstan.