This research was conducted to analyze the influence of social and economic factors on employee job satisfaction in the LAFAZA CV in Pekalongan City. Social factors and economic factors in this study include age, level of education, and work experience, the number of family were dependents, distance from home to work location, welfare, and working hours. Research social was was using survey methods. The method of determining the location of research determined purposively. Determination of the number of respondents sample population with a total was using of 37 respondents. The data analysis method use multiple linear regression. The results showed d that simultaneously social and economic factors including age, level of education, and work experience, number of family dependents, distance from home to work location, welfare, and social working hours had a significant effect with a level of confidence of 0.05 on employee job satisfaction


This paper will discuss the design of PI and PID controller tuning rules to compensate processes with delay, that are modelled in a number of ways. The rules allow the achieveme nt of constant gain and phase margins as the delay varies.


In particular during the descending phase of the solar cycle, Alfvén waves in the high-speed solar wind streams are a major form of interplanetary disturbances. The fluctuating southward interplanetary magnetic field (IMF) of Alfvén waves has been suggested to induce geomagnetic activities through intermittent magnetic reconnection at the magnetopause. In this study, we provide in situ observational evidence for dayside magnetopause reconnection induced by such interplanetary Alfvén waves. Using multipoint conjunction observations, we show that the IMF B z from interplanetary Alfvén waves is transmitted through and amplified by the Earth's bow shock. Associated with the intensified southward B z to the magnetopause, in situ signatures of magnetic reconnection are detected. Repetitively, interplanetary Alfvén waves transmit the intensified B z to the magnetosheath, leading to intervals of large magnetic shear angles across the magnetopause and magnetopause reconnection. Such intervals are promptly followed by hundreds of nanoTesla (nT) increases in the auroral electrojet indices (AE and AU) within 10–20 minutes. These observations are confirmed in multiple events in corotating interaction region-driven geomagnetic storms. To put the observations into context, we propose a phenomenological model of a strongly driven substorm. The substorm electrojet is linked to the enhanced magnetopause reconnection in the short timescale of re-establishing the ionosphere electric field and the two-cell convection. These results provide insights on the temporal patterns of solar wind magnetosphere–ionosphere coupling, especially during the descending phase of the solar cycle.


Dealing with the medical disputes is one important job of the medical administrator. The precaution of the medical disputes has close relation to communication management in the hospital. The authors discuss how to manage communication as to guard against medical dispute in the military hospitals located in the special economic zone.


This paper reports new accurate and scalable behavioral modeling for novel 3D field-programmable ESD protection circuits using Verilog-A, which enables post-Si on-chip and insystem ESD protection design simulation and verification. New field-programmable ESD protection devices were fabricated in CMOS-compatible processes utilizing SONOS and nano crystal dots structures. The ESD behavior models were developed from ESD testing results and verified in SPICE circuit simulation.


Objective To investigate the optimal time for applying glucocorticoid eye drops after pterygium resection with autologous corneal limbal stem cell transplantation. Methods Patients (n=120) who underwent pterygium resection with autologous corneal limbal stem cell transplantation from Jan 2009 to Jan 2010 in the Second People's Hospital of Zhuhai were randomly divided into 4 groups (n=30 in each): control group, drug group A, B and C. After surgeries, all patients were treated with 0.3% tobramycin eye drops and bovine basic fibroblast growth factor eye gel. Tobramycin eye drops were converted to tobramycin/dexamethasone eye drops on postoperative day 2, 4, and 6 in drug group A, B, and C, respectively. All patients received a postoperative 2- year follow up. The repair time of corneal epithelium, the period of graft edema, and the recurrence were compared among 4 groups. Results The repair time of corneal epithelium was significantly different among 4 groups (F=11.44, P0.05), with the longest of 7.20±1.75 d in drug group A and about 4 d in other 3 groups. A significant difference in the period of graft edema was noted among 4 groups (F=21.56, P0.05), with the shortest in drug group A (6.80±1.32 d) and the longest in the control group (13.30±2.36 d). Recurrent cases were found in other 3 groups except drug group B and the recurrence rate in the control group (20%) was significantly higher than that in other 3 groups (P=0.027). Conclusion Our results indicated that the optimal time for applying glucocorticoid eye drops after pterygium resection with autologous corneal limbal stem cell transplantation was the 4th day after surgeries. Glucocorticoid eye drops applied at this time point can markedly alleviate postoperative eye irritation symptoms, decrease the recurrence rate, while do not cause adverse effects such as intraocular hypertension and delayed healing of corneal epithelium.


In 2007, indigenous children in the rain forest of eastern Venezuela began dying from a mysterious disease. The local physician, healers, and epidemiologists could not determine the cause. When a second and third wave of deaths occurred in 2008, Conrado Moraleda, the president of the local health committee, gathered a team to carry out an investigation that state officials seemed unwilling to do. The team included Clara Mantini-Briggs, a Venezuelan public health physician, and her husband, Charles L. Briggs, a professor of anthropology at the University of California, Berkeley. They and three others visited 30 communities spread out across a large portion of the Amacuro Delta, where the Warao people distinguish their settlements from the tierra firma of the criollos (nonindigenous). Moving from town to town by motorboat, the group stumbled upon an important clue: some communities reported unusual behavior of and bites by Desmodus rotundus, the common vampire bat that can carry rabies. More evidence of this disease was presented by agonizing and telltale symptoms and a frightening mortality rate. The team halted its investigation early to notify state and national authorities. Despite extraordinary efforts, it was ultimately unsuccessful in convincing the Venezuelan government even that an epidemic had occurred, let alone one caused by rabid bats. Una enfermedad monstruo and Tell Me Why consider why parents found no good answer to the tormenting question "Why did my children die"? The two books offer different but compatible explanations. Their differences and similarities correspond to their authors and intended audiences. The first book prints a running dialogue among the members of the team as they recount their fear and pain, their driven investigation, and their discouragement in the face of no redress. Its four authors urge social science researchers to "collaborate with other discriminated-against populations and produce interpretations of the past and the present that allow us to build futures imbued with a politics of hope and justice" (28). They present a number of interconnected if only lightly theorized reasons health authorities failed the Warao communities, including corruption and unethical behavior (48), an unsympathetic and mechanistic bureaucracy


Genetic variability and divergence for ten economically important traits in 51 genotypes (50 mutant lines of mungbean variety K 851+ one control) in M generation were studied. Number of pods/plant for high GCV was recorded. While number of primary branches/plant and number of pods/plant showed high PCV. All the traits showed high heritability, whereas, plant height, number of primary branches/plant, number of clusters/plant, number of pods/plant and seed yield/plant showed high genetic advance. On the basis of D values, a total of five cluster were obtained, indicating that induced mutations are effective in creating genetic divergence. Maximum number of mutant lines were included in cluster I, cluster II and cluster III whereas only control was present in cluster IV. The maximum inter-cluster distance was recorded for cluster IV. Cluster V, Cluster I, cluster II and cluster IV were recorded for high plant height and maximum number of se seed index, pod length and number of clusters/plant. The results from the present experiment concluded that MML could be superior mutant line with high number of clusters per plant, number of pods per plant, seed index and seed yield per plant.


18. Given the si~nificant racial and socioeconomic differences that exist between the California electorate and its voters, this problem is also present statewide. See Garcia Bedolla (2005). For a discussion of racial differences in public opinion, see Dawson (2000). 19. These include five cities in Maryland: Takoma Park, Barnesville, Martin's Additions, Somerset, and Chevy Chase. Noncitizens can vote in school board elections in the city of Chicago. Noncitizen parents can vote for and serve on community and school boards under New York state education law so long as they have not been convicted of a felony or voting fraud. As of 1992, there were 56,000 noncitizens registered as parent voters in New York. See Harper-Ho (2000) and Hayduk (2002). 20. They find that Latino applicants are more likely to be denied citizenship on administrative grounds than those from other parts of the world. 21. This is largely because socioeconomic status has been found to be the strongest predictor of political participation, and most immigrants possess low socioeconomic status (see Verba, Schlozman, and Brady, 1995). In a study comparing native born and foreign born voting in New York state, Minnite, Holdaway and Hayduk (2001) find that nativity has a significant negative impact on participation rates across a number of modes of participation. 22. My thanks to Shawn Rosenberg and Molly Patterson for helping me to develop many of the ideas in this section. 23. For an overview of these perspectives, see Benhabib (1996), Cohen (1997), and Gutmann and Thompson (1996). 24. For an overview of the Alinsky approach to organizing within the Industrial Areas Foundation (IAF), see Marquez (2000). 25. This picture does have one very important caveat-given findings in my previous work and that of others that shows native-born hostility toward ~m migrants in the Latino community, it is important that those power relations not be reproduced within these deliberative contexts. See Garcia Bedolla (2003) and Gutierrez (1995). . Jus Meritum Citizenship for Service


The present investigation designed to evaluate the phytochemical and pharmacological activity of ethanolic extract of Solanum nigrum in experimental animal models. The ethanolic extract of S. nigrum was used in three different doses (100, 200 and 300 mg/kg bw) to evaluating anti-inflammatory and anti-convulsant activity by employing carrageenan paw edema and Supramaximal electric shock (MES) methods. Ethanolic extract of S. nigrum produced significant anti-inflammatory (P < 0.01) and anti-convulsant (P < 0.05) effect in dose dependent manner. The flavonoids present in the berries might be a responsible active constituent for this activity.

 Key words: Solanum nigrum, anti-inflammatory activity, anti-convulsant, flavonoids


Moire,a pattern of clothing,peculiar to China ,being popular for thousands of years,is rich in its cultural connotation and decorative implication. Based on an analysis of the structure and characteristics of Moire clothing,as well as their respective historic developments,this paper is to elaborate on the decoration practices,layouts and forms of expression applied in modern design of Moire,from the perspective of modern fashion design,so as to probe into Moire's current and prospective applicability.


A 25 year-old male presented with a tender, fixed 3-cm right parotid mass persisting over 2 years with recent interval enlargement. CT scan demonstrated a cystic mass that did not invade adjacent soft tissue or bone. Fine needle aspiration (FNA) yielded cyst fluid. Total parotidectomy with facial nerve dissection for a presumed parotid tumor demonstrated a mass tracking deep to the facial nerve, coursing medially and superiorly to terminate adjacent to the cartilaginous external auditory canal (EAC). Pathology revealed an epithelial-lined cyst with hair matrix surrounded by elastic cartilage in focal areas consistent with a Work type II first branchial cleft cyst with EAC duplication. This case supports the literature in demonstrating that 1. misdiagnosis occurs commonly and frequently necessitates revision; 2. full facial nerve dissection reduces incidence of its injury; and 3. increased familiarity with its clinical symptoms, inclusion on the differential for parotid masses, preoperative imaging, and identification of a tract in the specimen can reduce recurrence rates. Work type II first branchial cleft anomalies must be included in the differential diagnosis for head and neck masses above the level of the hyoid bone. Preoperative imaging, more so than FNA, can confirm the diagnosis. Improved diagnosis can ensure the appropriate surgical approach, and decrease the risk of post-operative complications. Mal-development of First Branchial Cleft Leads to External Auditory Canal Malformations 2 References 1. D'Souza AR, Uppal HS, De R, Zeitoun H. Updating concepts of first branchial cleft defects: a literature review. Int J Pediatr Otorhinolaryngol. 2002;62(2):103-9. 2. Benson MT, Dalen K, Mancuso AA, Kerr HH, Cacciarelli AA, Mafee MF. Congenital anomalies of the branchial apparatus: embryology and pathologic anatomy. Radiographics 1992; 12(5):943-60. 3. Blevins, NH et al. External auditory canal duplication anomalies associated with congenital aural atresia. J Laryngology & Otology 2003;117: 32–38. 4. Triglia JM, Nicollas R, Ducroz V, Koltai PJ, Garabedian EN. First branchial cleft anomalies: a study of 39 cases and review of the literature. Arch Otolaryngol Head Neck Surg. 1998;124(3):291-5. 5. Acierno SP, Waldhausen JH. Congenital cervical cysts, sinuses and fistulae. Otolaryngol Clin North Am. 2007;40(1):161-76, vii-viii 6. Martinez Del Pero M, Malumdar S, Bateman N, Bull PD. Presentation of first branchial cleft anomalies: the Sheffield experience. Laryngol Otol. 2007;121(5):455-9. 7. Schroeder JW Jr, Mohvuddin N, Maddalozzo J. Branchial anomalies in the pediatric population. Otolaryngol Head Neck Surg. 2007;137(2):289-95. 8. Solares CA, Chan J, Koltai PJ. Anatomical variations of the facial nerve in first branchial cleft anomalies. Arch Otolaryngol Head Neck Surg. 2003;129(3):351-5. 9. Jakubikova J, Stanik R, Stanikova A. Malformations of the first branchial cleft: duplication of the external auditory canal. Int J Pediatr Otorhinolaryngol 2005;69(2):255-61 10. Sichel JY, Halperin D, Dano I, Dangoor E. Clinical Update on type II first branchial cleft cysts. Laryngoscope. 1998;108(10):1524-7. Discussion


Among two groups of wild and reared zebrafishes (zf) Danio rerio, all meristic characters considered were variable except the numbers of rays and pterygophores of the dorsal fin and the principal caudal fin rays, which tended to be canalized. Wild and reared individuals differed in the number of intervertebrae and anal pterygophores, and the dorsal and anal fin insertion. There were some skeletal anomalies of vertebrae and fins, particularly the caudal fin. Cephalic and Weber-apparatus anomalies were rare. Types and frequencies of anomalies were quite similar in the two zf groups, but differences emerged for several less frequent anomalies. Such differences and the phenotypic variability of D. rerio make this species a perfect teleost model for investigating the influence of experimental or unfavourable environmental conditions on skeletal development of both domesticated and wild fish.


Severe disease — Patients with severe ulcerative colitis usually have a large region of the colon involved, often the entire colon. Symptoms of severe ulcerative colitis include Diagram of the colon and rectum Ulcerative Colitis (UC) is a disease in which the lining of the colon (the large intestine) becomes inflamed. The immune system mistakenly targets the lining of the colon, causing inflammation, ulceration, bleeding and diarrhea. The inflammation almost always affects the rectum and lower part of the colon, but it can also effect the entire colon


Objective: To investigate the relationship between thyroid dysfunction and blood lipid level. Methods: Two hundred patients with thyroid function problems admitted during April 2013 to March 2015 were enrolled for the study, including 100 cases each with hyperthyroidism or hypothyroidism, and 80 participants undergoing health maintenance examination during the same period served as control. The levels of thyroid hormones and blood lipids in all subjects were measured, and the correlation between their levels was analyzed.Results: By univariate analysis, significant difference was found in all the studied thyroid hormones and blood lipids among the three populations(all P0.05). Correlation analysis in patients with abnormal thyroid function showed that the level of thyroid stimulating hormone(TSH) had a positive correlation with the levels of total cholesterol(TC), low density lipoprotein cholesterol(LDL-C), and apolipoprotein B100(Apo B10)(r=0.695, 0.714, and 0.632); the level of free triiodothyronine(FT3) had a negative correlation with the levels of TC, LDL-C and Apo B100(r=–0.769, –0.705 and –0.689); the level of free thyroxine(FT4) had a negative correlation with the levels of TC, LDL-C and Apo B100(r=–0.728, –0.676 and –0.625)(all P0.05).Conclusion: Thyroid dysfunction may cause blood lipid metabolic abnormity, which deserves attention in clinical practice.


The Mask at the CRICOT1 Theatre: From the Pictorial to the « Operative » Gesture

The aim of this paper is to describe the beginnings, rather unknown, of the CRICOT theatre and to demonstrate the evolution which took place between the first show of CRICOT1 and the last piece performed in 1938. Focusing on the manners of treating the scenic object, the scenography, the costumes and the masks, the paper analyses the transformation of the amateur theatre: artistic, satirical, visual and comic into quasi-professional theatre, carrying an existential message. Message to be developed afterward by the world-famous collective, reformer of the European stages: Tadeusz Kantor's CRICOT2.


1. Irish approaches to European integration - Michael Holmes 2. The economic challenge of enlargement - Bernadette Andreosso-O'Callaghan 3. EU environmental policy and Ireland - Bernadette Connaughton 4. Europe and Ireland's changing security policy - Nicholas Rees 5. The development of opposition to European integration in Ireland - Michael Holmes 6. Irish public opinion and the new Europe - John Coakley 7. Ireland's European discourse and the nationalforum on Europe - John O'Brennan 8. Ireland and the convention on the future of Europe - Anna Verges Bausili 9. Northern Ireland and the future of Europe debate - Mary C. Murphy and David Phinnemore 10. Ireland's management of European business: The impact of Nice - Brigid Laffan 11. Ireland and the future of Europe - Michael Holmes and Nicholas Rees Index


Biometric verification assumes a noteworthy part in security as these are by nature interesting for each human. Be that as it may, the security is traded off when the example coordinating framework is not exact. Verification framework like unique finger impression acknowledgment is most ordinarily utilized biometric validation framework. In this paper overview is done on unique mark acknowledgment strategies. What's more, extraordinary methodologies are examined as far as precision and execution. As unique finger impression may likewise contain clamor; so picture de-noising systems are additionally concentrated Cross edge recurrence examination of finger impression pictures is performed by method for factual measures and weighted mean stage is ascertained. These distinctive components alongside edge unwavering quality or edge focus recurrence are given as contributions to a fluffy c-implies classifier.


JEADV 2006, 20 , 1133–1167 © 2006 European Academy of Dermatology and Venereology 1135 completely healed. The patient remained asymptomatic 12 months later. Superficial granulomatous pyoderma (SGP), as described by Wilson-Jones and Winkelmann, is a unique clinicopathologic entity presenting as a chronic granulomatous and pyodermatous lesion of the skin. 1 To our best knowledge, only 57 cases with the clinical course and histopathologic features considered characteristic for SGP have been reported to date. 1–9 The aetiology of SGP remains unclear but it may be a limited form of pyoderma gangrenosum. To date there is no clear relation with systemic diseases as seen with pyoderma gangrenosum. Succesful treatment of SGP has been described using local steroids, triamcinolone injections, tetracycline, minocycline, dapsone, trimethoprim-sulfamethoxazole and oral steroids. 1–5 Our case demonstrates that SGP is often misdiagnosed as a simple abscess or ulcer by primary care doctors or general surgeons delaying referral to dermatologist. Although there is no pathognomonic finding in the diagnosis of SGP, the chronicity of the condition and the characteristic three-layered granuloma seen on histopathology may help the clinician to make the correct diagnosis.


SOME fifty years ago Still1 and Wishart2 noted that jaundice exercised a profound and beneficial effect upon the syndrome of rheumatoid arthritis. Initial attempts by Hench3 to apply this finding to the clinical treatment of rheumatism by inducing artificial hyperbilirubinaemia by intravenous injection of bile salts and bilirubin, however, were not entirely successful, only slight transitory benefits, not comparable with those produced by naturally-acquired jaundice, being observed. More encouraging results were subsequently reported by MacCallum and Bradley4 and by Gordon, Stewart and MacCallum5 who induced jaundice with icterogenic serum in volunteer rheumatoid arthritic patients. Their results led them to conclude that the remissions induced in rheumatoid arthritis by an attack of jaundice were striking and showed that the disease was capable of undergoing considerable regression. Parallel with these investigations Hench, in America, was continuing studies initiated in 1929 on the beneficial effects of pregnancy and jaundice upon rheumatoid arthritis. By 1949 he was able to state6 that "the inherent reversibility of rheumatoid arthritis is activated more effectively by the intercurrence of jaundice or pregnancy than by any other condition or agent thus far known." He further conjectured that the beneficial effects thus encountered were due to a hypothetical "antirheumatic Substance X" which was not a disintegration product from a damaged liver, but a compound specific in nature and function and normal to the human organism. As temporary remissions of arthritis were known to follow procedures capable of stimulating the adrenal cortices, Hench turned his attention to the adrenal hormones, finally associating "antirheumatic Substance X" with cortisone6. The dramatic results, thereby achieved have inevitably given a powerful stimulus to the furtherance of studies on the relation between structure and action in the steroid group. Early in 1951 a programme of work was initiated in these laboratories on the preparation of certain analogues of cortisone for study as antiphlogistic agents. We had been greatly impressed by the clinical evidence linking remissions in rheumatoid arthritis with intercurrent jaundice. We had also accepted in large measure the explanation of this effect on the basis of Selye's "General Adaptation Syndrome" whereby jaundice is regarded as a stressor agent which imitates the physiological defence mechanism of the body by calling for increased production of antiphlogistic steroids'. At the same time we thought the results were capable of a different interpretation and one worthy of consideration. Disturbance of the excretory mechanism of the liver leads to jaundice


Theo Kneifel ended his paper with a series of questions. These questions suggest cenain directions for funher discussion and for action. I want to emphasise that ""and for action"", Karl Marx made the comment concerning philosophers that they had spent countless centuries speculating about the world but had done very little to change it.


Abstract This paper examines the implied standard deviation (ISD) estimated from transactons data on options, using the Black-Scholes pricing model. It was found that the distribution of the ISD is symmetric, though not normal. Also, the ISD based on the last daily observation deviates significantly from the daily average ISD. It is suggested that the daily average is a more reliable estimate of the standard deviation.


Category: Ankle, Trauma Introduction/Purpose: Isolated Lateral malleolus fracture, like any other fractures can be treated by operative or conservative treatment. Stability of ankle joint is the most important factor in deciding the type of treatment. Unstable ankle joints present superior clinical outcomes with surgical management. There are many methods to assess the stability of ankle joint such as plain x- ray films, stress radiographies and physical examination. Many studies have suggested the usage of ultrasound for diagnosis of ankle ligament injury. But, there are no reports about its use for stability assessment of isolated lateral malleolar ankle fracture. Therefore, the purpose of this study is to evaluate the value of ultrasound for stability assessment of isolated lateral malleolar fractures, compared to simple x-ray, stress radiography and arthroscopy. Methods: We have conducted a prospective study which included 13 consecutive patients who underwent arthroscopic exam and subsequent open reduction and internal fixation for isolated lateral malleolar ankle fracture. Before operation simple x-ray, external rotation stress radiographs were done. Stress ultrasound was performed to assess the anterior inferior tibiofibular ligament (AITFL) and medial deltoid ligament prior to operation. The arthroscopic findings were used as the reference standard. A standardized physical examination (tenderness and ecchymosis, external rotation stress test), simple radiography, stress radiography and ultrasound images were compared to assess the stability. Results: Deltoid ligament injury and or syndesmosis injury were verified arthroscopically in 12 cases with a clinical diagnosis (92.3%). There were 9 cases who showed unstable ankle fracture on the simple radiography. (69.2%). There were all cases who showed unstable ankle fracture on the external rotation stress radiography. (100%) In addition, for 12/13, there were acute tear of the deltoid ligament or AITFL injury on the ultrasound (92.3%). Conclusion: The results suggest that ultrasound could be used for the assessment of the instability of isolated lateral malleolar fracture.


This article outlines the development of the Open Doors network facilitator post in Greater Manchester West Mental Health NHS Foundation Trust. The post is unique in the NHS in that it is led and facilitated by Mike Howorth, a person with Alzheimer's disease. This article outlines the self-growth and wellbeing experiences of Mike as he re-entered the workforce in his early 80s after 15 years of retirement. Being the Open Doors network facilitator has provided Mike with new challenges and opportunities in his life, including facing up to, and overcoming, a life-long fear of public speaking. The achievements of the post are shared within Mike's overall story of his own wellbeing, as well as his ambitions for the post in the future.


Soft-x-ray studies have been made on paramagnetic Ni and interpreted in terms of the single-particle density of states. In particular, the ${M}_{2,3}$ emission spectrum has been investigated, using improved experimental techniques. Measurements were made at 960\ifmmode^\circ\else\textdegree\fi{}C, at an average pressure of 5\ifmmode\times\else\texttimes\fi{}${10}^{\ensuremath{-}8}$ Torr, using an oxide-free surface. Fine structure was observed in the spectrum. Although first-principles correction of self-absorption effects and satellite and subband overlap is not yet possible, careful consideration is given them, with the result that the ${M}_{3}$ band can be resolved from the accompanying structure in a plausible way. Most of its features can be taken with reasonable confidence to be characteristic of the true ${M}_{3}$ emission band. Comparison is made with earlier soft-x-ray results, with band calculations for paramagnetic Ni, and with ion neutralization and photoemission measurements on ferromagnetic Ni. Systematic variations in transition matrix elements and lifetime broadening appear important when relating any experiment with theory, and an aspect of each of these problems has been considered quantitatively. The variation obtained is more severe for the photoemission than for the soft-x-ray analysis. The ion-neutralization and soft-x-ray results appear closer to the single-particle density of states.


Through the analysis of corrosion of the crude oil bottom plate,the article gives some protective measures: to use pitch,to use electrochemistry protection,to use coating.It can raise live span more five years.


Background: The Get with The Guidelines (GWTG) heart failure (HF) risk score was developed in the GWTG inpatient HF registry to predict in-hospital mortality but has not been fully validated for po...


Objective To evaluate the therapeutic efficacy of intraventrieular infusion of urokinase accompanied with external bilateral ventricular drainage(EBVD) and cerebral fluid exchange on severe intraventricular hemorrhage (SIVH).Methods 36 patinents with SIVH was treatment group,this group was treated after EBVD with direct intraventricular iufusion of 20 000~40 000 u urokinase with 4 ml sterile physiological saline twice daily and closing the drainage tube for two hours each time,cerebrospinal fluid exchangt through lumbar puncture on the next day.The drainage tube was withdrawn when CT scan showed the ventricle was cleaned.The control group was treated by unilater- al ventrieular drainage and intraventricular infusion of urokinase.Results 48 hour after the operation,in the treatment group,27 patients (61%) returned to the consciousness,in the control group 17 patients (47.2%) returned to the consciousness,there were an obvious differ- enee between them(P0.05).In the treatment group,the hematoma was completely drained in 2~7 days(mean 4 days),7days after the operation,the hematoma was completely drained in 31 patients.In the control group,it was 2~15 days (mean 9 days),7days after operation the hematoma was completely drained in 23 patients,so that the duration of hematoma dissolving in the treatment group was shorter than con- trol group.The GOS at discharge in the treatment group:11 cases were in good recovery,17 cases in mild disablement.5 in severe disable- ment and 3 died.In the control group ,6 casas was in good recovery,14 in mild disablement ,9 in severe disablement and 7 died.Good recov- ery and mild disablement were regarded as effection.In treatment group,the effect rate was 80.6%,while in the control group,the effective rate was 55.6% ,there were an obvious difference in effective rate between the two groups.Conclusion Intraventrieular infusion of uroki- nase accompanied with EVD is simple,effective,safe and rehable in treating IVH.


In this paper, a simulation system based on commercial projector is proposed to test the optical navigation algorithms for autonomous planetary landing in laboratorial scenarios. The design work of optics, mechanics and synchronization control are carried out. Furthermore, the whole simulation system is set up and tested. Through the calibration of the system, two main problems, synchronization between the projector and CCD and pixel-level shifting caused by the low repeatability of DMD used in the projector, are settled. The experimental result shows that the RMS errors of pitch, yaw and roll angles are 0.78', 0.48', and 2.95' compared with the theoretical calculation, which can fulfill the requirement of experimental simulation for planetary landing in laboratory.


Background and objectives: Platelet‐specific alloantigens are important in neonatal alloimmune thrombocytopenia, posttransfusion purpura, refractoriness to platelet transfusions, and population genetics. Data are scarce on allele frequencies in ethnic groups other than whites and Asians. Materials and methods: Using allele‐specific restriction enzyme analysis, we studied the distribution of HPA‐1 and HPA‐2 alleles in six Brazilian Amazon tribes of Amerindians, belonging to five different language stocks. We compared these with the values obtained for blacks and whites. Results: Only the HPA‐la allele was found among 132 Amerindian chromosomes, compared with a gene frequency of HPA‐lb of 0.115 and 0.133, respectively, among blacks and whites. The frequency of HPA‐2b among the Amerindians (0.042) is lower than that obtained for blacks and whites (0.148 and 0.100, respectively), and the lowest thus far observed in a population of Asian origin. Conclusion: Differences in DNA polymorphisms in Amerindian populations have not only anthropological and genetic interest, but also practical applications when they involve coding regions that may change the functional or immunologic features of the protein.


We define the universal Hitchin discriminants in the case of $\mathrm{Sp}(2n)$ Hitchin spectral covers, describe their components, and express their divisor classes in terms of standard generators of the rational Picard group of the moduli spaces of such spectral covers with variable base curve.


From experience and earlier investigations it is clear that room acoustical details in recorded music or speech can only be heard in a room having a reverberation time shorter than the one in the room in which the recording was made. The acoustical properties of listening rooms influence the perceived acoustics of the recording. In earlier investigations, the practical impact of listening room impulse responses on recording room impulse responses was shown by convolving many random combinations of measured room impulse responses. For more insight in the impact of listening room acoustics on rendered acoustics, in this new research, convolutions of synthetic impulse responses have also been used. Both the effect of the decay rate and the amount of direct sound were taken into account, where the resulting change in an acoustical property is assumed to be negligible if it does not exceed the JND (Just Noticeable Difference). Both theoretical and practical cases show that during playback, the decay curve derived from the recorded impulse response turns into a curve with a slow attack and a concave level decay line. The more both impulse responses (recording and playback room) are diffuse and equal in decay rate, the higher the impact. Even when using nearfield playback, it is very difficult to reduce the negative impact of a listening room on acoustical details in a recording.


In implementing prostate cancer screening using photoacoustic imaging (PAI), transrectal delivery of light and transrectal ultrasound (TRUS) transducer for signal detection is the most commonly used approach for PAI system design. In this approach, energy-efficient light delivery and good alignment of laser excitation and acoustic detection are very important for optimal imaging sensitivity. The previously published works adopted dark-field illumination for their probes. In this study, we proposed and achieved bright-field illumination, which enables more laser energy to be delivered to the region of interest for imaging, resulting in higher sensitivity of the probe. Further, by using a single optical fiber instead of fiber bundle, the efficiency of laser transmission was significantly enhanced. The adoption of single optical fiber also enhances the flexibility of the probe for operation and lower the cost. A custom designed photoacoustic imaging system was built in this study to verify the feasibility of the probe for clinical translational application. The spatial resolution and enhanced signal-to-noise ratio (SNR) of the proposed probe were validated using PAI of phantoms. We demonstrated the use of probe in diagnosing prostate cancer in vivo using a canine model mimicking prostate cancer. Our results showed that the proposed probe could achieve high sensitivity and a wide field-of-view (FOV) in imaging prostate cancer. We also performed minimally-invasive real-time guidance of needle biopsy in ex vivo prostate, showing the potential of the probe for early screening of prostate cancer and early preventive treatment of prostate tumor.


Toward a Native American Critical Theory is the first book-length work of criticism to contextualize the recent developments in Native American literary and cultural criticism within the growing field of Native American critical theory. Elvira Pulitano does a fine job of identifying the political and critical tensions within this field of study. In four chapters devoted to the critical works of specific critics and their methodologies, Pulitano analyzes both the logic and ideological intent of Paula Gunn Allen's "Gynosophical Perspective," Robert Allen Warrior and Craig S. Womack's "Nativist Approach," Greg Sarris and Louis Owens's "Dialogic Approach," and Gerald Vizenor's "Liberative Stories and Strategies of Survivance." In her introduction Pulitano identifies that the aim of her study is to "begin a discussion about something called Native American critical theory," a discourse which as a non-Native critic she finds problematic to define, but does so with a methodology that privileges a postcolonial theoretical notion of cultural hybridity to the exclusion of "separatist" critical movements. Her book will encourage the type of postcolonial theoretical discussions of Native American literature that she seeks, but her reluctance to acknowledge the internal logic of "separatist" critical works is problematic when considered within the historical and political contexts of Native America. Identifying "Native American literature" as "the product of conjunctural cultural practices, the Euramerican and Native American," Pulitano argues, "whatever our geographic, cultural, or ideological position, we cannot dismiss such a crucial premise in our interpretative acts" (8). Applying this perception to the study of literature, Pulitano asks, "How could a Native American theory aim at a 'pure' form of (Native) discourse, untouched by the strategies of Western tradition, when Native American literature itself is a product of a crosscultural encounter?" (9). Pulitano claims that because Native writers write in English, have a "consistently high level of education," and create literature that is "already heteroglot by nature," those works, and their authors, are necessarily embodiments of cultural, epistemological, and artistic hybridity (2). As Native American literature is a product of cultural hybridity, Pulitano argues, how could Native scholars such as Allen, Womack, and Warrior "aim at developing a separatist form of discourse when they are heavily and inevitably implicated in the discourse of the metropolitan center?" (9). Pulitano uses this postcolonial catch-22 to undercut the arguments of Allen's, Womack's, and Warrior's criticism, identifying what she sees as logical inconsistencies in an attempt to dismantle their critical projects.


A frequency measurement model to Superheterodyne Receiver in SIMULINK simulation entironment was proposed, especially focusing on the pivotal steps of the modeling and the main performance parameters of the simulation. The' lowpass equivalence' principle was applied to the modeling of Superheterodyne Frequency Measurement Receiver, corresponding mathematics simulation procedure was built up, the method of detection threshold determination was discussed in detail in the case of known SNR and unknown SNR, and the simulation example was given based on SIMULINK simulation platform. Each module block was described detailedly, brief frequency measurement performance analysis was done according to the typical simulation result. Results show that the method was correct and effective.


To validate the usefulness of subacromial bursa lidocaine for determination of the therapeutic steroid injection site in patients with adhesive capsulitis


Abstract : BIRDS EYE 6-69 was a regularly scheduled Arctic Ocean ice reconnaissance mission covering the Canadian Archipelago, Baffin Bay, and the area west of Banks Island from 5 to 17 September 1969. Ice observations contained in this report were made under daylight conditions. Weather conditions were excellent west of Banks Island and throughout Parry Channel; conditions elsewhere varied from poor to good. Remnant ice in Baffin Bay exceeded extreme conditions depicted in H.O. Publication 705 (Oceanographic Atlas of the Polar Seas). Parry Channel was ice free from Baffin Bay to near Resolute; however, icebergs existed in eastern Lancaster Sound. Seven to eight oktas of heavily puddled ice existed in Viscount Melville Sound and M'Clure Strait with some refreezing. Lesser conccentrations occurred within 30 nautical miles of Prince of Wales Strait. Shelf ice fragments were sighted within the pack ice. The icebreaking tanker SS Manhattan was located near 74 deg 36 min N, 104 deg 30 min W. Ice data from special flights made in April and May are included. Ice data obtained in the Canadian Archipelago and Polar Basin areas during April and May 1969 are also included. (Author)


There are much in the method of the development of American cartoon that China can make use of. As an important part of cultural industry, the industry of Chinese catoon must take some measures, in orde to develop well and make contribution to Chinese culture.


From heroic propagandist tales of space exploration to post-apocalyptic dystopias of the Chernobyl era, the history of Soviet sci-fi from the 1920s to the 1980s mirrors the rise and fall of the USSR itself. James Blackford probes the lost world unveiled in a new BFI season


Each year, hundreds of thousands of jurors judge a defendant's guilt. Understanding factors that influence their judgments is crucial. Both attractive-leniency bias and juror gender influence their decisions (Kulka & Kessler, 1978; Meaux et al., 2018; Papenbrook, 2013; Scroggs, 1976; Stewart, 1985). The present series of studies ( N =110 Study 1; N = 82 Study 2; N = 68 Study 3) explored these factors in addition to the type of crime by using mixed factorial (Studies 1 and 3) and between-subjects (Study 2) designs. I hypothesized that there would be a statistically significant interaction between type of crime and level of attractiveness. Women were hypothesized to deliver harsher sentences. With some variation, participants viewed versions of criminal scenarios (motor-vehicle theft, rape, murder) with or without a defendant's mugshot and selected the appropriate sentence (Studies 1-3) and decided on guilt (Study 3 only). Neither hypothesis was supported in Study 1 or 2. In Study 3, the hypothesized interaction was found between attractiveness and type of crime on sentence severity, p < 0.001, r 2 = 0.18. The "attractive criminal" is sensationalized in media. The results from the current series of studies provide hope for the American legal and justice systems as people are not necessarily making judgments of guilt and enforcing harsh sentences based purely on the defendant's looks.


CONNECT Magazine October 2010CONNECT is our monthly magazine for members. You'll find feature articles and member news including exhibit openings and important conservation achievements. Connecting Kids with Nature POST WZAM, MIRP, Ocean Project Research What Do We Know? (Members Only) Educating the Educator (Members Only) Education Liaison


The utility model discloses a data acquisition transmission instrument adaptable to various on-line monitoring systems, which comprises a microcontroller MCU, analog quantity access interfaces, digital quantity access interfaces, a storage unit, a real-time clock circuit and a power supply, wherein the analog quantity access interfaces, the digital quantity access interfaces, the storage unit and the real-time clock circuit are respectively connected with the microcontroller MCU, and the power supply supplies power to each electrical unit. Besides, the analog quantity access interfaces and the digital quantity access interfaces are more than one, analog quantity signals inputted by the analog access interfaces are transmitted to the microcontroller MCU after passing through signal adjusting circuits, A/D converting circuits and signal isolating circuits, the signal adjusting circuits, the A/D converting circuits and the signal isolating circuit are more than one, and the signal adjusting circuits are voltage/current self-adaptive circuits corresponding to the microcontroller MCU. The data acquiring transmission instrument is simple in structure, small in volume, reasonable in design and convenient in wire connection, and can effectively resolve the problem that various analog signals are incompatible during usage of the existing data acquisition instruments.


This is an attempt of a semantic classification of contemporary Chinese verbs based on common grammatical features in verb groups that are determined by their inner semantics. As a model, the author uses a universal predicate classification described by Vladimir Plungyan in An introduction into general morphology: a tutorial (M.: Editorial URSS, 2000). Chinese verbs appear to easily fit into its framework which suggests the universal nature of semantic categories. One of particular difficulties in Chinese language is interpreting the meaning of an isolated verb stem, as it only reveals its true meaning within a syntactic structure. The author provides a large number of examples corroborating these conclusions.


Machine-‐to-‐Machine (M2M); and many others – is giving birth to a completely interconnected world. In this world, every entity (be it a machine, a daily object, a person, or anything) can have a globally locatable, addressable, and readable virtual counterpart, which can collaborate with each other in the provisioning of various services. This concept is slowly becoming a reality: specific standards are being developed, new research results are being obtained, and novel services are being provided by both newborn start-‐ups and experienced companies in various areas (e.g., SCADA systems, smart grids, smart cities). However, several significant obstacles hinder the full implementation of this concept, and among them are the security issues. In fact, as there is already a parallel economy exploiting the foundational weaknesses of the Internet, this new environment will surely be targeted by original and ingenious malicious models. The challenge here is to prevent the growth of such models or at least to mitigate and limit their impact. Therefore, it is necessary to provide strong foundations to those paradigms that require it (such as IoT), and develop various robust and resilient security mechanisms that allow the secure interaction between entities even in restrictive contexts. Precisely, the goal of this special issue is to publish cutting-‐edge research results and innovation case studies that will help to set the security foundations of this new interconnected world. Topics of Interest In terms of security challenges, topics of interest include but are not limited to: • Novel security problems and challenges. • Privacy risks and data management problems. • Identifying, authenticating, and authorizing entities. • Development of trust frameworks for secure collaboration. • Cryptographic primitives and algorithms for constrained devices. • Secure connection of heterogeneous ecosystems and technologies. • Legal challenges and governance issues. • Fault tolerance and resilience to external and internal attacks. • Context-‐Aware security. • Security of cloud-‐based M2M/IoT platforms. • Distributed policy enforcement and rights management. • Usability of security and privacy technologies. • Security in social interactions between virtual entities. Submission Papers must represent high-‐quality and previously unpublished works. Original research papers are solicited in all relevant areas (IoT, M2M, etc) on the topic of security for the completely interconnected world. All submissions will be peer reviewed by at least three experts working in the areas. The guidelines for prospective


ABSTRACT Admission handoffs between emergency physicians (EPs) and internal medicine/hospitalist physicians (IMHPs), a frequently occurring form of patient transfer, remain understudied despite their importance to care continuity. Handoffs function as more than simple information transfer; they require a repertoire of interpersonal skills to accomplish tasks and develop professional relationships. Relational Dialectics Theory (RDT), a perspective that asserts social life consists of oppositional and unified discourses present in personal relationships, frames the current study. We use role dialectics to more fully understand the contradictions that emerge from the competing discourses of physician roles. Data were collected from six focus groups consisting of residents and attending physicians working at a large, urban, academic medical center in the Midwest United States. Using a grounded, constant-comparative approach, analysis of transcripts reveals that these physicians encounter two key role dialectics during handoffs: autonomy–collaboration and uncertainty–certainty. Interventions for physicians and hospital decision-makers are recommended.


This study assesses the climate trends of precipitation in a large number of locations in the Abruzzo region for the period 1951-2009. It highlights the reduction of annual precipitation, starting in 1980, due to a significant decrease in winter rainfall amount. This phenomenon seems to be the mesoscale realisation of a more general process that concerns the European area as the result of the new configuration of the Atlantic circulation that has been established through the '80 years of the 20th century.


INTRODUCTION
Little has been published on the impact of telephone visits on diabetes outcome performance.

RESEARCH DESIGN AND METHODS
An attending and resident physician prioritized telephone visits based on glycemic, blood pressure, and lipid performance. The resident and attending panel was compared with all other diabetic patients at the clinic for baseline and end-intervention performance.

RESULTS
The intervention patients had an absolute percentage of increase versus control patients of 14.9 (p<0.01), 13.9 (p<0.01), and 8.3 (p=0.01) for HbA1c <9%, low-density lipoprotein <100 mg/dL, and blood pressure <130/80 mm Hg, respectively.

CONCLUSIONS
This pilot study suggests that provider-driven telephone visits may be a means for healthcare systems to improve chronic disease outcomes as they transition to new paradigms of chronic care delivery.

LIMITATIONS
This study was neither randomized nor blinded, was susceptible to an interventionist effect, and did not analyze for differences in baseline medication use.


A well-preserved contact aureole at the base of the sheeted dyke is likely to be centred at, or very close to, the sheeted complex in the Troodos ophiolite, Cyprus, records the partial melting dyke–gabbro boundary. This region of the crust is a of the roof of a mid-ocean ridge magma chamber. Hydrothermally dynamic environment that is subjected to rapid changes altered dykes within the lowermost 10–30 m of the sheeted dyke in rheology and thermal structure. It is here that melt is complex were recrystallized to pyroxene and hornblende hornfels episodically extracted to build the upper crust (e.g. Deand, closest to the underlying gabbros ( 30%) at water-undersaturated conditions and temperatures if not all, of the lower crust (e.g. Phipps Morgan & Chen, [875°C. Geological considerations indicate that the duration of 1993; Quick & Denlinger, 1993; Boudier et al., 1996), melting events was probably on the time scale of eruptive cycles (i.e. and magmatic heat is rapidly transferred across a thin years to centuries). This resulted in disequilibrium partial melting (<100 m) conductive boundary layer (e.g. Lowell & and highly imperfect melt segregation within the contact aureole. Burnell, 1991) and advectively transported out of the We hypothesize that partial melting is a common process within crust by hydrothermal fluids (e.g. Cann et al., 1985). the roof zones of axial magma chambers at fast-spreading ridges Geophysical surveys along the East Pacific Rise (EPR) and that a component of geophysically imaged axial magma chambers provide indirect evidence that the depth and internal may be partially melted upper crust rather than partially crystallized properties (e.g. melt volumes, proportion of melt and magma. Field relations suggest that where the highest degrees of crystals) of AMCs are not static and change on the time melting occurred, a mixture of anhydrous hornfels and hydrous scale of eruptive cycles (years to centuries) (Wilcock & leucocratic melt disaggregrated, and was assimilated into the magma Delaney, 1996; Singh et al., 1998). chamber. It is well known from ophiolite studies that the roofs of AMCs can be marked by polyphase magmatism and intense interactions between hydrothermal fluids and rocks, particularly within the uppermost few hundred


Eight new palladium(II) complexes with 4-toluenesulfonyl-L-amino acid dianion and 1,4-dab/1,3-dap, [Pd(1,4-dab)(TsglyNO)] · H2O (1), [Pd(1,4-dab)(TsvalNO)] (2), [Pd(1,4-dab)(TsleuNO)] (3), [Pd(1,4-dab)(TsileNO)] (4), [Pd(1,4-dab)(TsserNO)] · 0.5H2O (5), [Pd(1,4-dab)(TspheNO)] · 0.5H2O (6), [Pd(1,4-dab)(TsthrNO)] · H2O (7), and [Pd(1,3-dap)(TsserNO)] (8), have been synthesized and characterized by elemental analysis, IR, UV, 1H NMR, and mass spectrometry. Crystal structure of 8 has been determined by X-ray diffraction. The cytotoxicities were tested by MTT assay. The results indicate the complexes exert cytotoxic effects against HL-60 and Bel-7402. The structure–activity relationship suggests that both amino acids and N-containing ligands have important effects on cytotoxicity, but the IC50 values do not show definite correlation with variation of these ligands.


Background: Chronic anovulation is a common cause of infertility. Anovulation leads to a long-term problem such as hyperandrogenism. Anovulation usually associated with amenorrhoea about 20% and oligomenorrhoea of women with ovulatory dysfunction. Present study was designed to assess the incidence and etiological factors responsible for anovulation in infertility cases. Methods: Study comprised of one hundred patients attending the outdoor clinic of the department for infertility either primary or secondary with regular and irregular menstrual cycles and patients of secondary amenorrhoea. Results: Among the total cases Polymenorrhoea was seen in 10% of cases, oligomenorrhea in 14% cases, secondary amenorrhoea in 3% and 73% cases had normal menstrual cycle. cervical mucus viscosity in ovulatory group to be low in 84.6% cases, moderate in 8.5% cases and high in 38% cases. In anovulatory cycles findings were reversed with viscosity at 14th day it was moderate in 27.27% and higher in 54.54% cases. Conclusions: Cervical mucus is a good indicator of the cyclical changes in ovarian hormonal as no false positive results were found. Endometrial biopsy is the mainstay in infertility studios as it provides information regarding the ovulating status.


Purpose: Intraoperative colonic distension is associated with postoperative ileus, which contributes to a delayed hospital discharge. A randomized and prospective study was conducted to evaluate the usefulness of intraoperative needle decompression of the colon (IDC) during a radical gastrectomy for gastric cancer. Methods: Fifty patients that had received subtotal or total gastrectomy for gastric cancer were randomly assigned to either a non-decompression (n=27) or a decompression group (n=23). Prior to the main procedure, the transverse or right colon was pulled up, and a 19-gauge disposable needle connected to suction was introduced to the colon through the taenia site of the anterior wall. Any gas that collected in the colon was aspirated. The time to the first postoperative passage of flatus or feces was measured precisely in order to evaluate the restoration of bowel function. Additional measures of the outcome were the operation time, the complication rate and the length of hospital stay. Results: Demographic details, pathologic features, operation times, complication rates and the length of hospital stay were not different between the two groups. A collapsed colon was required for good surgical exposure and easy manipulation. No unexpected complications related to the procedure were found. The average time to the first flatus was 6.8 hours sooner in the decompression group than in the non-decompression, although this result was not stati-stically significant. Conclusion: This technique is a simple and safe procedure for intraoperative colon decompression during a radical gastrectomy.


To the historian the map has traditionally been used as little more than a descriptive or illustrative device which helped clarity of exposition by enabling events to be located, campaigns comprehended and treaties interpreted. It was not in itself regarded as a critical instrument of analysis, other than in highly specialized, peripheral studies such as the history of exploration. Maps simply illustrated arguments based on documentary evidence; the map as a document, original or secondary, was regarded with great suspicion. Undoubtedly the inaccuracy of early maps was partly to blame, especially to an historian more concerned with delineatory accuracy than with what was contemporary perception of the world. But even if historical maps were acceptable in evidence, the derivation of conclusions from mapped material was barely permissible and usually, in reviews, the subject of severe warning if not actual stricture. These attitudes have largely disappeared over the last decade in line with changes in direction of historical research. Perhaps the earlier influence came from pre-historic archaeology, where in the nature of things there was no documentary evidence and inference had to be made from the distribution of characteristic artifacts. This, in itself, taking its methodology from geographical or locational analysis, has been translated into a study adopting sophisticated methods for the analysis of distribution patterns. Another important influence has been the majestic work of H. C. Darby in interpreting Domesday in cartographic terms and thereby demonstrating the significance of such an approach to a widely known historical document. Even so, it is in urban history that the use of map evidence and mapped material has made the greatest impact.


Background/Aim : To examine, in vitro, the effect of soluble egg antigen (SEA) of S. haematobium on intracellular HCV RNA load in peripheral mononuclear cells (PBMC) as well as on cell proliferation in patients with chronic HCV infection. Methods: PBMC from 26 patients with chronic HCV infection were cultured for 72 hours in presence and absence of 50 μg SEA / ml medium. Intracellular HCV RNA quantification of plus and minus strands was assessed before and after stimulation. PBMC from five healthy subjects were cultured for 7 days, flow cytometric analysis of DNA content was used to assess the mitogenic effect of SEA on PBMC proliferation compared to phytoheamaglutinine (PHA). Results: Quantification of the intracellular viral load showed increased copy number /cell of both or either viral strands after induction with SEA in 18 of 26 patients (69.2%) thus indicating stimulation of viral replication. Flow cytometric analysis showed that mean ± S.D. of percent values of cell proliferation was induced from 3.2 ± 1.5% in un-stimulated cells to 16.7 ± 2.5 % and 16.84 ± 1.7 % in cells stimulated with PHA and SEA respectively. Conclusion: the present study supports earlier reports on SEA proliferative activity on PBMC and provides a strong evidence that the higher morbidity observed in patients co-infected with schistosomiasis and HCV is related, at least in part, to direct stimulation of viral replication by SEA.


Finite mixture models and mixture multivariate regression models have been widely used for the modeling and analysis of data from a heterogeneous population. Moreover, this kind of data can be subjected to some upper and/or lower detection limits because of the restriction of experimental apparatus. Another complication arises when measures of each population depart significantly from normality, for instance, in the presence of heavy tails or atypical observations. For such data structures, we propose a robust model for censored data based on finite mixtures of multivariate Student-t distributions and a regression model for censored data based on finite mixtures of multivariate Student-t distributions. This approach allows us to model data with great flexibility, accommodating multimodality, heavy tails and also skewness depending on the structure of the mixture components. We develop an analytically simple yet efficient EM-type algorithm for conducting maximum likelihood estimation of the parameters. The algorithm has closed-form expressions at the E-step, that rely on formulas for the mean and variance of the multivariate truncated Student-t distributions. Further, a general informationbased method for approximating the asymptotic covariance matrix of the estimators is also presented. Results obtained from the analysis of both simulated and real data sets are reported to demonstrate the effectiveness of the proposed methodology. The proposed algorithm and methods are implemented in the new R package CensMixReg.


Smith-Magenis Syndrome (SMS) is a rare (1/15,000 - 25,000 births) neurodevelopmental disorder resulting from an interstitial deletion of chromosome 17p11.2, or from a point mutation in the RAI1 gene. Severe sleep disorder is almost universal in patients with SMS and poses a significant challenge to patients and their families. Tasimelteon improved sleep symptoms in a randomized, double-blind, two-period, crossover study; and here we show that this effect persists for up to four years in an open-label extension. To our knowledge, this is the largest interventional study of SMS patients to date.

 Following the 4-week crossover study, all eligible participants had the option to enroll in an open-label extension. 31/39 (79.4%) of all individuals who participated in the efficacy study have continued on tasimelteon treatment. Participants in the open-label extension provided daily diary sleep quality (DDSQ), and daily diary total sleep time (DDTST) measures via parental post sleep questionnaire and characterized behavior using the Aberrant Behavior Checklist (ABC).

 In the open-label extension, tasimelteon continued to show improvement in the primary endpoints of 50% worst sleep quality (mean = 0.7, SD = 0.94) and 50% worst total nighttime sleep duration (mean = 53.3, SD = 59.01) when compared to baseline. Tasimelteon also improved overall sleep quality (mean=0.7, SD=0.83) and overall total nighttime sleep duration (mean = 51.9, SD=53.03). ABC scores also improved with tasimelteon (mean= -16.3, SD = 15.82).

 Tasimelteon continues to demonstrate persistence in efficacy (longest approximately 4 years) with similar magnitudes observed in the 4-week crossover study for sleep quality and total sleep time. Interestingly, daytime behavior also demonstrates long-term improvement in patients with SMS treated with tasimelteon. These results further confirm tasimelteon as a novel therapy for the treatment of sleep disorders in patients with SMS and may provide benefit for behavioral symptoms.

 This work was supported by Vanda Pharmaceuticals Inc.


Objective—Carotid plaque instability is a major cause of ischemic stroke, but detailed knowledge about underlying molecular pathways is still lacking. Here, we evaluated large-scale transcriptomic and protein expression profiling in a biobank of carotid endarterectomies followed by characterization of identified candidates, as a platform for discovery of novel proteins differentially regulated in unstable carotid lesions. Approach and Results—Genes highly upregulated in symptomatic versus asymptomatic plaques were selected from Affymetrix microarray analyses (n=127 plaques), and tissue microarrays constructed from 34 lesions were assayed for 21 corresponding proteins by immunohistochemistry. Quantification of stainings demonstrated differential expression of CD36, CD137, and DOCK7 (P<0.05) in unstable versus stable lesions and the most significant upregulation of a proprotein convertase, PCSK6 (P<0.0001). Increased expression of PCSK6 in symptomatic lesions was verified by quantitative real-time polymeras...


This detailed investigation of the operating system and control program for a small model robot teaches lessons that the student can later apply in industry.


secured messaging they through two face-to-face evaluations with Our study provides evidence of a significant decrease in psychopathological levels and severity of bulimic behavior of patients who used the IBT. Furthermore, the program helps bulimic patients to re-establish self-control over eating behavior and to reduce the emotional component associated with this disorder, such as anxiety. The first eight weeks of treatment demonstrated to be a crucial period in order to achieve a correct therapeutic adherence. We also proved that the success rates for this therapy were significantly higher (in statistical and clinical terms) than for control groups which did not received any intervention. Therefore, this online self-help approach appears to be a valid treatment option for controlling bulimic symptoms in adult women.


Writer identification in multi-lingual/script environment is a challenging problem for researchers due to the variations in styles, texts and scripts. In this paper an attempt is made to identify the writer independent of the script he has written. The stroke length and stroke density in 8 directions are extracted as a feature vector of size 16 and used the nearest neighbor classifier with 5-fold crossvalidation. The experiment is conducted on 1200 documents collected from 100 writers for three scripts Roman, Kannada and Devanagari each with four documents. Each document has only one script. The experimental results have shown average accuracy for writer identification of documents of two scripts written by same writer in Roman, Kannada as 79.4455%, in Roman, Devanagari as 78.4204% and in Kannada, Devanagari as 76.5027% where as for documents of three scripts shown average accuracy of writer identification as 74.6646% for random input document, when individual scripts considered the writer identification accuracy is 90.3677% for Roman (English), 85.4177% for Kannada and 84.3217% for Devanagari (Hindi) scripts. The proposed method also gave promising results for script identification in biscript and tri-script scenario i.e. script recognition accuracy in Roman, Kannada is 99.1000%, in Roman, Devanagari is 99.7000%, in Kannada, Devanagari is 99.8250% and in triscript combination the accuracy is 98.5333%. KeywordsDirectional strokes, writer identification, script identification, stroke length, stroke density.


Tea growing in Rwanda started in 1952 and by 2002 tea had become the country's largest export item. However, an increase in tea farm land has been constrained by population growth, impacting the quantity of tea that the country produces. Tea exports are volatile and are influenced by the real effective exchange rate, incomes of major trading patterns, total investments as a proportion of GDP, tea world market prices and coffee world market prices. There is little recent empirical research on factors affecting Rwandan tea exports. This study assesses the causality between tea exports and their determinants in Rwanda. The study applies a causal research design and uses time series data collected from different sources. It uses the Granger causality test to test for predictability between exports and their factors. The research concludes that non-causality in the long term was possible because before the late 1980s Rwanda had an economy that was based on a prestructural adjustment program when exports were under total control. Short-run causality was possible because after the 1980s, a decline in world tea prices may have led to an increase in exports as demand increased in the short run. What is needed now are more investments in tea factories, diversification of commodities that are exported, prioritizing forward selling or contracting and widening niche markets for tea products.


For the first time a Web-catalog of microwave electronics has been created with IATP international program support. The catalog is distinguished by a combination of both a database on the devices produced by the Russian and worldwide industries, and the data concerning the new microwave electronic devices development in the frequency bands of 3-300 GHz.


The dissociation constants and the equivalent conductances of 2,4-dinitrobenzoic acid and D-10-camphosulfonic acid have been determined in water-methanol mixtures at 25 °C. The experimental data have been analyzed with the "Fuoss 78" conductance equation. The Bjerrum critical distance was accepted instead of Gurney's cosphere diameter. Values of KA and Λ0 are reported.


Objective To study the feasibility of exogenous gene transfection to bone marrow mesenchymal stem cells (MSCs). Methods MSCs obtained from bone marrow of 4 adult Newzealand rabbits were cultured and treated with recombinant pcDNA3.1(+)-EGFP with the help of lipofectamine. The transgene results were confirmed by fluoroscopy and the cell viability post transfection was evaluated by light microscopy and electron microscopy. Results Bone marrow MSCs were successfully transfected with pcDNA3 carrying EGFP gene and the exogenous gene expression continued for over 8 weeks. Cell viability was not significantly influenced and no cell toxicity was observed. Conclusion Bone marrow MSCs can be efficiently modified by appropriate gene transfection through recombinant technique.


A novel ionic liquid bonded polysiloxane ([PSOMIm][NTf2]) was prepared through synthesizing ionic liquid bonded stationary phase with Cl- and a anion exchange reaction to replace the chloride anion with bis[(trifluoromethyl)sulfonyl]imide (NTf-2) anion. The polymer was thermal stable and the thermogravimetric test indicated that the [PSOMIm][NTf2] began to decompose slightly after 380 ℃. Then a capillary tube (8 m×0.25 mm i.d.) was coated by static method to prepare a gas chromatographic column. The chromatographic performance was evaluated and demonstrated. The result showed that the [PSOMIm][NTf2] stationary phase exerted good selectivity and high thermal stability for Grob reagent mixture and many types of compounds. The present study suggests that the novel ionic liquid bonded polysiloxane stationary phase has a great potential for further study and application.


FIELD: communication. SUBSTANCE: invention relates to wireless communication, particularly to cooperation mode activation of the user device. Disclosed is a communication system comprising: user device and base station, wherein the user device performs a first communication with the base station in a first communication system and the second connection - with the second communication system. User device includes: memory device to store information on configuration of the cooperation mode; transmitting device for transmission radio resource control signalling to the base station with indication for entering in the cooperation mode after detecting interference from the second communication system; and receiving device for receiving information on the cooperation mode. Base station includes: receiving device for receiving radio resource control signalling from the user device with said indication; and a mode control device for selecting the cooperation mode, in which the user device is allowed to enter, according to the state of the system for the first communication system, cooperation mode is a method of multiplexing with time or frequency division. EFFECT: technical result is communication with devices of two communication systems simultaneously using different transmission resources. 1 cl, 15 dwg


ABSTRACT Drawing from an ethnographic study with families who relocated from the United States to Mexico, I explore what I call parents' transborder pedagogies of the home, or the home-based educational practices that adults with experiences across transnational institutions draw upon to prepare their children for life and learning on both sides of the border. I argue it is important to understand parents of forced repatriation as transborder thinkers who draw upon a range of transnational knowledges that push against mononational expectations to educate their children and make challenging schooling decisions. Findings illustrate how caregivers and children may vary in their alignment regarding these decisions, especially when U.S.-born children's return to the United States for schooling would entail new arrangements of family separation due to the lack of authorised pathways for their parents' return.


5 th National Conference on Local Safety and Security Introductory Discussion on Safety and Security in Urban and Rural Environments: Conference Proceedings Conference proceedings comprise peer-reviewed papers presented at the 5th National conference on safety and security in local communities, which took place in Nova Gorica in November 2019. Safety and security in local communities remain the main topic of annual conferences, however, dichotomy between urban and rural safety and security was highlighted this year. Papers present the result of research within the framework of the research programme Safety and security in local communities – comparison of rural and urban environments, conducted at the Faculty of Criminal Justice and Security, University of Maribor. Papers focus on various aspects of safety and security in urban and rural local communities in Slovenia, namely on the regulation of the fundamental right to safety at the local level; cooperation between the police and local community in solving security problems; differences and comparison of crime and perception of security problems in local communities; and different perspectives on safety and security in local communities (self-protective measures of residents, corruption, cybersecurity).


such as tuberculosis, sarcoidosis and schistosomiasis may cause galactorrhoea.14 A fifth of women with galactorrhoea have pituitary tumours but this rises to about a third if they have amenorrhoea too.16 Two biochemistry tests showed low serum prolactin, ruling out a prolactinoma. Unfortunately, LS did not attend for her endocrinology review or her CT brain scan. Although LS has a recent low HIV CD4 cell count, she had not been on treatment with anti-retroviral agents (which may contain protease inhibitors). Galactorrhoea may be a rare idiosyncratic side-effect of long-term opiate use, perhaps caused by fluctuations in hormone levels, perhaps independent of prolactin. The mechanism remains unclear.


A number of designs have been proposed for completely on-chip reference current generation but suffer varying degrees of drawbacks. The author presents a new design that provides a robust on-chip current reference circuit for submicron technologies without the usual disadvantages.


Osteoarthritis (OA) is the most common form of arthritis with a high socioeconomic burden, with an incompletely understood etiology. Evidence suggests a role for the transforming growth factor beta (TGF-s) signalling pathway and epigenomics in OA. The aim of this thesis was to understand the involvement of the TGF-s pathway in OA and to determine the DNA methylation patterns of OA-affected cartilage as compared to the OA-free cartilage.
First, I found that a common SNP in the BMP2 gene, a ligand in the Bone morphogenetic protein (BMP) subunit of TGF-s pathway, was associated with OA in the Newfoundland population. I also showed a genetic association between SMAD3 - a signal transducer in the TGF-s subunit of the TGF-s signalling pathway - and the total radiographic burden of OA. I further demonstrated that SMAD3 is over-expressed in OA cartilage, suggesting an over activation of the TGF-s signalling in OA. Next, I examined the connection of these genes in the regulation of matrix metallopeptidase 13 (MMP13) - an enzyme known to destroy extracellular matrix in OA cartilage - in the context of the TGF-s signalling. The analyses showed that TGF-s, MMP13, and SMAD3 were overexpressed in OA cartilage, whereas the expression of BMP2 was significantly reduced. The expression of TGF-s was positively correlated with that of SMAD3 and MMP13, suggesting that TGF-s signalling is involved in up-regulation of MMP13. This regulation, however, appears not to be controlled by SMAD3 signals, possibly due to the involvement of collateral signalling, and to be suppressed by BMP regulation in healthy cartilage, whose levels were reduced in end-stage OA.
In a genome-wide DNA methylation analysis, I reported CpG sites differentially methylated in OA and showed that the cartilage methylome has a potential to distinguish between OA-affected and non-OA cartilage. Functional clustering analysis of the genes harbouring differentially methylated loci revealed that they are enriched in the skeletal system morphogenesis pathway, which could be a potential candidate for further OA studies. Overall, the findings from the present thesis provide evidence that the TGF-s signalling pathway is associated with the development of OA, and epigenomics might be involved as a potential mechanism in OA.


Introduction: "Clinical competency" is a complicated concept which is important in nursing profession for safe caring. However; there is no certainty on clinical competence definition as the kind of psychiatric nursing services changes based on context. A clear definition of clinical competency leads to identify the essential components and its application in research or clinical practice and provides the best possible standards of care. The aim of present study was to analyze the clinical competency concept to identify its attributes, antecedents and consequences. Methods: Six step Rodgers' concept analysis method was used. First, the key words were selected with reviewing articles. The key words of psychiatric nurse, clinical competency,competence, nursing, students , in databases of SID, PubMed, Archives of psychiatric nursing , IJPN were searched in Persian and English in single or combind. Regarding the evidences time period between 1980 to 2018 and the psychiatric context were selected for data collection. Among 300 original articles and tow primary books, 195 articles were excluded with regard to inclusion criteria and 105 articles remained. According to Rodgers' approach, 20% of the sources were included in the research. The Alternative words, attribute, antecedents and consequence were explained and conceptualized. Results: The terms ability (42.85%), adequacy (4.76%), preparation (14.28%), skill (61.90%) and competency (4.76%) were used as substitution for clinical competency. 2 categories of general and specific traits were defined. Antecedents were individual, environmental and organizational factors. Consequences of Clinical competency of psychiatric nurses are enhancement of health services quality, decreased medical mistakes, increased safety, decreased costs and enhanced nursing profession. Conclusions: Psychiatric nursing clinical competency is careful and continuous incorporation of therapeutic communication with, professional skills, specialized knowledge and clinical reasoning, emotions and values appropriate to context for psychiatric nursing interventions that, individual, environmental, organization are influential factors. Definition of clinical competency leads to have practical indicators for objective evaluating, formation of a framework for training based on index, and the basis for providing the competency license. The re-analysis of the concept by hybrid method is needed.


The electronic module (7) for the marking of the blade tip to a lighting system formed by a power source (3) arranged on the rotor (2) a transmission system (4) optical fiber extending integrates along the blade (1), a converter (5) and a light module (6). The electronic module is formed by a power circuit and a control arranged in the tip of the blade (1) and encapsulated to avoid rays. # The method of operation of the electronic module (7) selects the illumination of the blade ( 1) during the oN interval corresponding to 120 ° of the upper zone rotation and remains off and feeding of energy during the OFF interval corresponding to the lower area of rotation.


In surface roughness prediction modelling, it is crucial to do away with insignificant variables. Retaining variables that are not statistically significant can lower the formulated model's accuracy. This paper is a presentation of the Bayesian Linear Regression Model (BLRM) in assessing the impact of predictors in surface roughness prediction of single point diamond turned RSA 443 with the assistance of acquired acoustic emission signal parameter (AErms) and primary cutting parameters. The principles behind the BLRM are presented in this paper. It has been observed that the order of decreasing impact of the parameters is as follows: cutting speed, feed rate, depth of cut and AErms. Furthermore, it has been discovered that the regression model containing cutting speed and feed rate has the best prediction power. Depth of cut and AErms have high probabilities of being rejected as linear regression predictors (0.642 and 0.754, respectively). Validation of the variable responses using p-values at 0.05 significance level has produced the same order of variable significance as that produced by the BLRM. Hence, the BLRM can be reliably utilized as a parameter significance assessment prediction tool.


Target detection of hyperspectral image has always been a hot research topic, especially due to its important applications in military and civilian remote sensing. This paper employs the idea of classification and proposes a novel detection framework which incorporates dictionary learning and discriminative information. Due to the fact that target pixels lie in different subspace with background pixels, a novel detection model is proposed. In addition, a linear kernel is applied to project the image data into high-dimensional space, separating the target pixels and background pixels. Synthetic image and popular real hyperspectral image are used to evaluate our algorithm. Experimental results indicate that our proposed detector outperforms the traditional detection methods.


Present research work investigates the significance of accounting information on equity share investment in companies listed on Indian Stock Exchange. The accounting information variable used to establish the significance of accounting information on equity share investment. The study investigated the influence of financial information on equity share investment decision making. Primary data is used for the study. Data for the study were collected from a sample of 177 respondents invested in equity market. The study indicates that investor's information seeking behaviour is based on their year of experience, their investment horizon and their investment intention. The study also indicated that years of experience has no significant impact on investment source choice. Similarly it was found that investment horizon has no significant impact on investment source choice.


The present invention provides for a limit with the synchronous non-adaptive retransmission scheme, provides a method of using deforming the synchronous non-adaptive retransmission scheme. Further, by using the data scheduling message includes not only the transmission of new data, we propose a method of instructing retransmission. Furthermore, we propose a method of performing through other messages received since an error of judgment for reception confirmation signal transmitted from the reception side data. Further, retransmission method in a multi-carrier system, the step of scheduling for data retransmission is set as the first retransmission scheduling before retransmission, receives a grant message to include the scheduling information for uplink data transmission, wherein the step of transmitting the uplink data by the scheduling information, identified as case retransmission is required to said data, comprising the step of: retransmitting said data by a second retransmission scheduling information for the data.


Following the regulatory excesses of the 1970s and the reforms of the 1980s, the policy pendulum is swinging back again. On the surface, the government imposing socially desirable requirements on business seems to be a cheap way of achieving national objectives. But every time a government agency attempts to safeguard the environment or foster occupational health or promote product safety, it imposes a more expensive method of production on businesses. Consumers, meanwhile, suffer by paying for these hidden regulations.


The cuticular retention and penetration of ¹¹⁵ᵐCd (metastable cadmium-115) were studied using isolated pear (Pyrus communis L. 'Passe Crassane') leaves, and apple (Malus pumila Mill. 'Akane') and tomato (Lycopersicon esculentum L.) fruit cuticles to obtain a better understanding of the behavior of Cd deposited on the aerial parts of plants. Results show that Cd, as CdCl₂, may be taken up by isolated cuticles. The mean value calculated from results obtained with different cuticular species was 1.4 µg Cd/cm² with CdCl₂ (11.8 mg Cd/L, pH ≈ 6). The cuticular retention depended greatly on the plant species when results are expressed on the basis of the dry weight. The study of the washing with water or exchange solutions suggests that the retention corresponds to a fraction sorbed as solute and to another fraction constituted by exchangeable Cd ions. At first it increased rapidly, then progressively tended to a saturation level as the concentration varied from 0.5 mg to 1.1 g Cd/L. It was observed with dewaxed cuticles that the cuticular matrix was predominantly implicated in the retention. There appeared an interaction with Zn, suggesting a competition for the same sites of fixation. It was possible to reveal the cuticular penetration of Cd through intact cuticles; it was very slow but was greater with diluted HCl than with pure water as a receiver. These results are consistent with data obtained from experiments on entire plants, showing that the greatest part of Cd deposited on leaves is recovered at the deposit place.


Cotton is one of mostly attacked crop by sucking insect pests, out of which Jassid Amrasca biguttula biguttula (Ishida) (Homoptera: Cicadellidae) has become one of the serious pest of this crop. The present study was conducted on different selected genotypes of the Bt-cotton to find out the role of the physico-morphic and chemical plant characters on the population fluctuation of jassid. The effects of physico-morphic and chemical plant characters of Bt-cotton were correlated with the jassid population and their role was calculated by processing the data into simple and multiple linear regression equation. The maximum variations were observed among the resistance and susceptible genotypes of Btcotton due to plant height, hair density, thickness of leaf lamina, leaf area, length of hair, moisture percentage and total minerals. The results revealed that hair density on midrib, vein and lamina had negative and significant correlation, length of hair on midrib and vein had non significant correlation while Thickness of leaf lamina exerted positive and significant correlation with the Jassid population per leaf. Gossypol glands on midrib and vein showed positive and significant correlation while on lamina had negative and significant effect. Total minerals exerted positive and significant effect whereas reducing sugar, calcium and manganese showed negative and significant correlation with the Jassid density. Multiple linear regression models revealed that hair density on midrib and total minerals in the leaves were the most important characters.


Aerobiology as a term was coined in the 1930's to describe a multi-disciplinary research area with the aim of increasing the knowledge of how biological particles in the atmosphere are transported, become airborne, deposited and their biological effects. The biological particles considered in aerobiology covers both microorganisms, for example bacteria, fungi, algae and viruses, as well as spores, pollen, seeds, insects and other biological material. This review mainly deals with micro-organisms, their transmission in the atmosphere and their negative effects on humans, animals and plants. Reports and reviews that cover other aerobiological particles are numerous and will only briefly be dealt with here.


Two massive wooden doors comprising a gate assembly, associated with structures dating to the Republic of Texas period, were to be displayed. This necessitated stabilization. One door was in stable condition, while the other was not and required immediate treatment. Although never buried, the doors may be considered as subarchaeological remains due to their advanced state of decay, which is similar to that found in non-waterlogged archaeological wood. The project included: 1) wood identification; 2) examination of the door nails to determine any chronological information; 3) identification of the associated insect remains to provide information on species responsible for wood damage 4) stabilization of the wood with consolidants and with structural gap-filling materials; 5) exhibition in an upright position in a display frame.


This report reviews existing mathematical and/or computer simulation models that estimate xenobiotic deposition to and transport through (both curricular and stomatal) vegetative surfaces. The report evaluates the potential for coupling the best of those models to the existing Uptake, Translocation, Accumulation, and Biodegradation model to be used for future xenobiotic exposure assessments. Here xenobiotic compounds are defined as airborne contaminants, both organic and gaseous pollutants, that are introduced into the environment by man. Specifically this document provides a detailed review of the state-of-the-art models that addressed aerial deposition of particles and gases to foliage; foliar and cuticular transport, metabolism, and uptake of organic xenobiotics; and stomatal transport of gaseous and volatile organic xenobiotic pollutants. Where detailed information was available, parameters for each model are provided on a chemical by chemical as well as species by species basis. Sufficient detail is provided on each model to assess the potential for adapting or coupling the model to the existing UTAB plant exposure model. 126 refs., 6 figs., 10 tabs.


[Objective] The aim was to optimize the extraction technology of polysaccharides from Coprinus comatus fruit-body.[Method] With the water as the extraction solvent,the effects of extraction temperature(60,70,80,90 ℃),extraction time(2,3,4,5 h),solid-liquid ratio(1∶10,1∶20,1∶30,1∶40) on the yield of polysaccharides from C.comatus fruit-body were investigated by the single factor experiments and the extraction technology was optimized by using the orthogonal experiment.[Result] The single factor experiments showed that the optimum extraction temperature,extraction time and solid-liquid radio were 4 h, 90 ℃,1∶30 resp.The orthogonal experiment showed that the effect of extraction temperature on the yield of polysaccharides from C.comatus was the largest,the second was the extraction time and the effect of solid-liquid radio was the least.The optimization technology suitable for local conditions which was selected through optimizing extraction condition and combining the comprehensive factors of benefit,cost and so on was as follows: the extraction temperature was 90 ℃,the extraction time was 3 h and the solid-liquid radio was 1∶30.The verification test showed that the yield of polysaccharides extracted under the optimum technology condition was 7.99%.[Conclusion] The recovery rate of the optimization technology was up to 98%,showing that the technology condition was stable and suitable for the industrial production.


Type III ground states of hcp vector antiferromagnets—appropriate to the wurtzite magnetic semiconductors (MS) such as Zn1−xMnxSe —are shown to be classically unstable at long wavelengths. The Hamiltonian includes antiferromagnetic nearest‐neighbor (NN) and next‐nearest‐neighbor (NNN) isotropic exchange (J1,J2), and NN anisotropic Dzyaloshinsky–Moriya exchange (D). The hexagonal symmetry allows Ja1 for NN in planes perpendicular to the c axis to be different from Jc1 for NN between planes. For three‐component spins a five‐dimensional degenerate manifold of type III ground states is found (Ja1=Jc1, D=0). Their instability is investigated through a continuum formulation of the exchange energy, treating D and ΔJ≡(Ja1−Jc1) as small compared with J1. ΔJ is found to induce a twist of a noncollinear ground state, stabilized by D to zeroth order. By fitting the shift δQ of magnetic peaks seen in neutron scattering experiments on Zn0.45Mn0.55Se the required ΔJ/J1 (∼δQ) is found to be 0.06. This value agrees with e...


New anion surfmers of the family of maleic acid asymmetrical esters have been synthesized. Some of its features in the process of emulsion copolymerization with styrene have been studied. The characteristics of covering, obtained on the basis of such latexes of new generation have been investigated as well.


Microscopic samples of the fluids in the vicinity of growing crystals can be trapped in defects called fluid inclusions. These have the potential to provide geologically significant information. Based on experience with an earlier system a new dual mass spectrometer system has been developed for analysing volatiles in individual fluid inclusions. Small mineral samples weighing about 10 mg are heated in a vacuum and as each inclusion decrepitates it produces a burst of gas lasting about 30 ms (for the geometry of the system). The gases are continuously pumped away through a pair of quadrupole mass spectrometers that scan overlapping ranges of 1–70 and 67–140 u in less than 25 ms. Mass spectrometer outputs are digitized, interleaved, combined with temperature data and stored on 9-track tape. Off-line processing locates each individual burst and subtracts the local background to give the inclusion composition. Mass spectra for individual inclusions can be displayed or groups of inclusion data can be combined on ternary diagrams. Release of any volatile components as a function of temperature can be monitored and displayed. These analytical techniques are applicable to a wide range of minerals.


Patient no. 1, a 61-year-old man with mild haemophilia B [factor IX (FIX) 11%], underwent screening colonoscopy. Recombinant FIX (rFIX) concentrate 90 IU kg was infused immediately before the procedure. Three polyps measuring 5–7 mm were found and removed without difficulty using coldsnare technique with the concurrent application of monopolar electrocautery. Diverticula were scattered throughout the sigmoid colon, and small internal haemorrhoids were also identified. No excessive bleeding occurred. Patient no. 2, a 54-year-old man with severe haemophilia A [factor VIII (FVII) <1%], received epsilon-aminocaproic acid (EACA) 2.6 g 1 h before screening colonoscopy. Recombinant FVIII (rFVIII) was available in the endoscopy suite but was not needed during the procedure. No lesion requiring biopsy or removal was identified, and the colonoscopy concluded uneventfully.


The purpose of the current research study was to establish reliability and validity of an assessment high-leverage practice rubric (HLPR-A). Five raters scored 33 participants' instructional videos two times using the HLPR-A. Interrater and intrarater reliability was established using an intraclass correlation coefficient. Content validity was established through expert review. Construct validity was presented using a nomological network. Internal validity was confirmed using principal axis factor analysis. The results revealed the HLPR-A to be a reliable and valid tool for assessing preservice teachers' performance when interpreting and communicating assessment information to a parent during a parent-teacher conference using mixed reality virtual simulations. Future research could explore using the HLPR-A on other populations, with a variety of raters, in other environments, and programs.


In order to study the influence of quadrangular height difference of the bogie on the operation safety of a 25T railway passenger coach, a multi-rigid-body dynamical model is built. In numerical simulations, the quadrangular height difference of a twisted type, a pitch type and a roll type are investigated, respectively. It shows that the quadrangular height difference has a negative effect on the operation safety, namely the derailment coefficient and the wheel unloading rate. It is found that the twist type affects most, followed by the roll type and the pitch type in turn. When the quadrangular height difference increases, the derailment coefficient and the wheel unloading rate increase. When the quadrangular height difference reaches up to 12 mm, the vehicle can be operated safely at 160 km/h on tangent track and at 90 km/h on a curved track with a radius of 500 m as well as passing through a twisted track at a quite low speed.