1. McGee DC, Gould MK. Preventing complications of central venous catheterization. N Engl J Med 2003;348:1123-33. 2. Fabbroni D. Anesthesia for hepatic transplantation. Contin Educ Anaesth Crit Care Pain 2006;6:171-5. 3. Gbaguidi X, Janvresse A, Benichou J, Cailleux N, Levesque H, Marie I. Internal jugular vein thrombosis: Outcome and risk factors. QJM 2011;104:209-19. 4. McGee WT, Ackerman BL, Rouben LR, Prasad VM, Bandi V, Mallory DL. Accurate placement of central venous catheters: A prospective, randomized, multicenter trial. Crit Care Med 1993;21:1118-23. 5. Agrawal P, Gupta B, D'souza N. Coiled central venous catheter in superior vena cava. Indian J Anaesth 2010;54:351-2. 6. Gibson F, Bodenham A. Misplaced central venous catheters: Applied anatomy and practical management. Br J Anaesth 2013;110:333-46. 7. Withington PS, Carter JA. Hazards in multiple cannulation of a single vein. Anesthesia 1985;40:700.


The invention relates to the field of healthy products, and in particular relates to a traditional Chinese medicinal composition and application thereof, a healthy product and a preparation method thereof. The traditional Chinese medicinal composition is prepared from maca, oyster extract and medlar extract, has a remarkable synergetic effect in the fields in relieving physical fatigue compared with a single dosage, can be used for effectively relieving physical fatigue, and has a durable effect.


The invention discloses a method for allocating frequency spectrum resources based on honest cooperation in a composite cognitive radio network, which comprises the allocation processes: firstly, access networks estimate respective minimum bandwidth demands and inform a network reconfiguration manager of the minimum bandwidth demands; secondly, the network reconfiguration manager dynamically allocate the frequency spectrum resources to the access networks according to a cooperative game model and a Nash bargaining method; thirdly, the network reconfiguration manager calculates utility loss brought by one access network in all the access networks to the other networks in sequence, takes the utility loss as a cost factor of the access network and calculates the cost required to be paid by the access network; and fourthly, the network reconfiguration manager respectively transmit the allocated frequency spectrum resources and the cost to the access networks. The invention not only can effectively encourage the access networks to honestly put forward the minimum bandwidth demands, remit the situation of excessive use of the frequency spectrum resources at pains on the basis of satisfying the frequency spectrum demands of each access network, improve the whole utility of all the access networks, but also can be used for dynamically allocating the frequency spectrum resources in the composite cognitive radio network.


This paper proposes a second-order sliding mode-based damping controller of DFIG for interarea oscillations. The proposed damping control strategy aims to utilize the reactive power modulation ability of DFIG to stabilize the power system in the event of oscillations caused by disturbances. First, the proposed controller is derived based on a two-area power system, and then it is extended to multiarea power systems. Compared with the conventional damping controller, the proposed one is insensitive to modeling uncertainties and parameter variations. Given the wide variation of operation points, the proposed sliding mode-based damping controller demonstrates a better robustness than the conventional damping controller. Simulation results on a two-area power system and a 10-machine 39-bus power system with DFIG-based wind farm integration show the improvement on system performance in interarea oscillation damping and demonstrate the robustness of the proposed control scheme in a wide operation region.


Biological tissues adapt to changed loading conditions through growth and remodelling (G&R) to reestablish a so‐called homeostatic state. On the other hand, loading conditions above their physiological limits, as during trauma or surgical procedures, cause injury and can initiate pathological G&R. Herein, a modelling approach for G&R influenced by injury is presented combining the theories of plasticity and homogenised constrained mixtures. The results show that injury has a significant impact on the G&R behaviour and thus on the accomplishment of homeostasis.


One of the currentmain challenges in the areaof scientific computing is the design and implementation of accuratenumerical models forcomplex physical systems which aredescribed by time dependent coupled systems of nonlinear PDEs.This volume integrates the works of experts in computational mathematics and its applications, with a focuson modern algorithms which are at the heart of accurate modeling: adaptive finite element methods, conservative finite difference methods and finite volume methods,and multilevel solution techniques. Fundamental theoretical results are revisited in survey articles and new techniques in numerical analysis are introduced. Applications showcasing the efficiency, reliability and robustness of the algorithms in porous media, structural mechanics and electromagnetism are presented. Researchers and graduate students in numerical analysis and numerical solutions of PDEsand their scientific computing applications will find this book useful.


This study aims to determine the validity and reliability of the mathematical ability test used to measure the effectiveness of mathematics learning by using modules. The tests compiled are validated by experts which include mathematics education lecturers and mathematics teachers and the results are valid and can be used without revision. Then the test was tested on the fourth-grade students of SD Negeri Sepatan 1. There were as many as 4 pieces of mathematics ability tests that were tested. Testability 1 contains ordinary fractional material consisting of 5 items. Capability test 2 contains pure fractional material 3 items. Capability test 3 contains mixed fractional material consisting of 3 items. Capability test 4 contains decimal fraction material consisting of 2 questions. Based on the test results of the ability test 1, 2, 3, and 4 analyzed with the help of SPSS version 21.00 for windows, the results obtained are based on inter-item correlation values> 0.05, which is valid. While based on the value of Cronbach's Alpha, a significance value of α> 0.05 is obtained, which is reliable. Thus the ability test items 1, 2, 3, 4 are valid and reliable.


Abstract : The mode analysis of ELF and VLF waves has been generalized to allow arbitrary directions of propagation below a curved stratified ionosphere with a dipping static magnetic field. In the ELF range, the propagation parameters are changed almost linearly with the azimuthal angle phi by varying the direction of propagation from East to West. In the VLF range, the phase velocity exhibits its maximum value for propagation in South and North direction; and minimum values occur for propagation towards West. Also, maximum attenuation rates occur for propagation towards West. Measured interference distances D of the two lowest wave-guide modes have been explained using nighttime ionosphere models which exhibit sharp density gradients in the height range from 80 to 85 km. (Author)


The present study includes the recent finds in the Barro Negro locality (Humahuaca, Jujuy, Argentina). Description and most important coments of this remains are developed. Chronological and stratigraphycal aspects are also included.


Sparse matrix—vector multiply is an important operation in a wide range of problems. One of the key factors determining the performance of this operation is sustained memory bandwidth. In the IBM POWER architecture, there is a hardware component called a prefetch data stream that can significantly increase sustained memory bandwidth. We have developed a new family of storage formats for sparse matrices that exploits this capability. Test results show that our new streamed storage formats can significantly improve the performance of sparse matrix and vector multiply on IBM POWER processors, compared to traditional compressed sparse row and block compressed sparse row formats. The new formats also provide a benefit on x86 processors.


disease, and that when both conditions are present, the clinical significance of each can be properly evaluated. This report is based on a study of fifty consecutive patients with diaphragmatic hernia. The age range was between 40 and 60 years; a few were younger and some were older. About onefourth had gastrointestinal complaints alone. A few presented only cardiovascular symptoms. Almost three-fourths of the patients had a combination of dyspepsia, dysphagia, and the like, and such symptoms as pain in the chest, palpitation of the heart, rapid heart rate. To determine the existence of organic coronary disease, the following clinical examinations were done: teleoroentgenogram, roentgenoscopy, resting electrocardiograms, including Wilson unipolar precordial and extremity leads, the "2-step" exercise electrocardiograms and the 10 per cent anoxemia test. These were correlated with the history, operative findings, post-mortem findings, and clinical follow-tip. We arrived at the conclusion that uncomplicated diaphragmatic hernia gives no objective evidence of coronary artery disease. When chest pain is present, it is usually not associated with effort. With rare exceptions, when precordial or substernal pain on effort occurs in the presence of diaphragmatic hernia, the foregoing objective tests uncover the customary evidence of organic disease of the coronary artery. A hiatus hernia may be the trigger mechanism in the precipitation of angina pectoris when coronary sclerosis exists. From both the physiological and clinical point of view, it is of interest that anemia, hematemesis or melena, severe diarrhea, vascular collapse or shock, all of which not infrequently occur in conjunction with diaphragmatic hernia, are precipitating factors in acute coronary insufficiency, especially in patients with antecedent coronary sclerosis. Co-existence of the two diseases is easily verified in this group, too, by the objective tests already enumerated.


The present invention relates to formulations containing the derivative and therapeutic methods of using certain cystine derivatives due to defects of the immune system disease.


Surficial sediments collected in 1984 and 1985 in the marine coastal belt and in the final stretch of rivers flowing in the San Rossore zone were analyzed for ten trace elements using atomic absorption spectrophotometry. Inter-element relationships as well as those with grain size and organic carbon contents were examined before interpreting the data obtained. The results indicate that rivers flowing in this area and especially the river Morto, are subject to anthropogenic input of Cr, Cd, Hg, Pb, Cu and Zn. The remobilization of several elements in the estuarine zone and their possible involvement in the deterioration processes of coastal vegetation of the San Rossore park, are discussed.


Cold working individual layers during additive manufacturing (AM) by mechanical surface treatments, such as peening, effectively "prints" an aggregate surface in tegrity that is referred to as a glocal (i.e., local with global implications) integrity. Printing a complex, pre-designed glocal integrity throughout the build volume is a feasible approach to improve functional performance while mitigating distortion. However, coupling peening with AM introduces new manufacturing challenges, namely thermal cancellation, whereby heat relaxes favorable residual stresses and work hardening when printing on a peened layer. Thus, this work investigates glocal integrity formation from cyclically coupling LENS® with laser peening on 420 stainless steel.


A mathematical model to study the diffuse transmitted fields by a phase screen is formulated in a similar way to the method applied for the scattering calculation by metalic rough surfaces. Micro-optic elements can be designed with such calculations applied to integrated optics.


Currently, there is contradictory evidence for the risk of adverse pregnancy outcomes associated with maternal exposure to disinfection byproducts (DBPs). We examine the association between maternal exposure to trihalomethanes (THMs) in drinking water and adverse pregnancy outcomes, including premature birth, low birth weight (LBW) and small for gestational age (SGA). In total, 1,167 women older than 18 years were enrolled at public antenatal venues in two geographical districts. For each district, we measured the levels of residential drinking water DBPs (measured in THMs) through regulatory data and routine water sampling. We estimated the individual uptake of water of each woman by combining individual water use and uptake factors. Increased daily internal dose of total THMs during the third trimester of pregnancy significantly increased the risk of delivering premature infants (AOR 3.13, 95% CI 1.36–7.17). The risk of premature birth was also positiviely associated with exposure to total THMs during the whole pregnancy (AOR 2.89, 95% CI 1.25–6.68). The risk of delivering an SGA and LBW infant was not associated with maternal exposure to THMs. Our findings suggest that exposure to THMs is associated with certain negative pregnancy outcomes. The levels of THMs in water should be routinely monitored.


Identification of fault location by victimization phasor activity unit's .victimization Vector activity Units by using Phasor measurement unit. Phasor measurement unit finds the fault in mille secs, so it conjointly offers time synchronous data of voltage and current in binary format and provides required knowledge to the native Hub Vector (PDC). Once if the heavy-scale distractions like power failures occurs, the prevention and management of the reaction should be taken. Proposed device successively replace to a stable state by reducing the clash of the distractions.WAMS is the study of grid connected power system in large area under observation. The frequency is measured in the grid and observation of the frequencies of the various grids depends upon with


"I want you to try and get me on the panel of that HMO as a PCP (primary care provider)." With that one seemingly simple request, a medical subspecialist can launch an administrative colleague down a difficult path-one where issues of economic success may be pitted against continuity of patient care, and where subspecialty medical providers may find themselves faced with very difficult choices-or even with no choice. How did such a difficult situation come about, and what do managers within health care systems consider as they weigh their responses to these requests for HMO panel participation?


Objective To understand professional attitude of preschool teachers and its relations with the psychological health condition. Methods To make self- restraint professional attitude questionaine and the SCL-90 evaluation on 427 female preschool teachers,and analyze its relevant factors. Results The professional attitude score of preschool teachers was(5.37±1.27), the professional attitude scores of teachers,which more than 40 years old, technical school education, salary per month under RMB 1000 were below other teachers(P0.05), overall score of SCL-90 was(1.12±0.05), professional attitude score of preschool teachers had significantly negative correlation with somatization,obsession,dep ression,anxiety(P0.05).Conclusion The overall professional attitudes of preschool teachers are neutral with positive tendency, professional attitudes can be influenced by psychological health condition.


Six populations of Cypripedium flavum were studied on their genetic diversity, genetic structure, and clonal diversity in Zhongdian County, Yunnan Province (South-west China). Using POPGENE software, 86 polymorphic loci was obtained using two AFLP primer combinations, and the proportion of polymorphic loci was 82.69%. A relatively high level of genetic diversity was revealed: H e =0.2884, H o =0.4312 (at species level); P=64.59%, H e =0.2449, H o =0.3606 (at population level). Genetic differentiation among populations was not high ( G st =0.154). A relatively high level of gene flow was obtained among populations. Clonal diversity of populations was high ( D =0.9638 - 0.9960, G/N=0.83 - 0.96), and ramets of same genotype were adjacent. C.flavum was found with high level of genetic diversity. This may be explained by gene heterozygosity increasing by seedling recruitment and maintaining by clonal reproduction.


Software systems are increasingly expected to cope with variable workloads, component failures and other uncertainties through self-adaptation. As such, self-adaptive software has been the subject of intense research over the past decade. Our work focuses on the use of self-adaptive software in applications with strict functional and non-functional requirements. These applications need compelling assurances that the software continues to meet its requirements while it reconfigures its architecture and parameters at runtime. To address this need, we introduce an end-to-end methodology for the ENgineering of TRUstworthy Self-adaptive sofTware (ENTRUST).


Tourism in the country following a series of categories of services which play an important role in the country's per capita income and employment. Iran, despite having a privileged position in terms of historical attractions, natural and geographical and climate four seasons from the perspective of tourism and tourism indicators in place is not desirable. If we consider, in particular, sports tourism as an industry, it can be considered clean and adequate source of income and In order to exploit this area of the sports industry, managers and planners need current and new application methods and careful planning are the strategic and operational levels Something that the city of Ramsar, Mazandaran province, especially due to its well-known global level has been neglected. In this paper we are going with respect to the potential of the city of Ramsar in tourism and sport tourism especially, to identify the strengths of the city, prioritize them and evaluate current and potential opportunities to deliver their actuality And strategic planning of sports tourism industry in the city of Ramsar in particular and its extension to the in Mazandaran province and the country in general, too.
Keywords: sports tourism, natural attractions – sports, ecotourism, city of Ramsar


The article presents the person of Michal son of Andrzej of Domaslaw, parson at Slupca (1439-1447), a town of the bishops of Poznan, former notary of the Gniezno consistory. Emphasis is placed on his involvement for the parish, especially his activity connected with his experience as notary (cases held at the Gniezno consistory in defense of the parish benefice and legates for the Slupca parish, concern for documentation of the legates). The study contains also a list of parsons in Slupca in the first half of the 15th century. The whole is complemented by excerpts from consistory acts showing the personal decisions of Michal of Domaslaw (resignation from the practice of the profession of notary, testament) as well as his activity as parson in Slupca.


This paper seeks to analyze the role that literature has performed throughout the last years, the conflicts derived from the academic views, and how literature is an essential tool for the comprehensive study of a second language, as an integral part of the educational process. The Model suggested enhances the figure of the teacher and promotes the skills, knowledge and attitudes of the students within a multicultural environment.


The dielectric relaxation studies of liquids and liquid mixtures is a tool to understand intermolecular interaction along with molecular dynamics. Although m-Fluoroaniline (MFA) has higher dipole moment than methanol (MT) has dielectric constant less than that of methanol. H-bonds appear in methanol but not in m-Fluoroaniline. The dielectric behavior, dielectric relaxation mechanism of these pure liquids and their binary mixtures helps to understand nature of interactions between dipoles and effects of molecular bonding. Higher dielectric constant and relaxation time of of pure methanol compared to those of m-Fluoroaniline are due to presence of H-bonding and parallel alignment of electric dipoles. In pure m-Fluoroaniline spatial correlation between molecules appear only through dipole-dipole interactions. To study these aspects the Time domain Reflectometry technique has been used to obtain complex dielectric spectra of binary mixture of MT and MFA in the frequency range of 10 MHz to 10 GHz at various temperatures the results are presented.


Here, we tackle the paradigm that direct bonding of planar wafers is not suitable on non-planar substrates. In doing so, we also present a new method for measuring the interface surface energy. This yields first guidelines for manufacturing novel optical components which combine different optical properties.


In this paper, we consider particular exposure scenarios to evaluate human effects for inductive commercial wireless charging device operating at low frequency. The coil used in this study is the A10 model in Qi standard proposed by WPC(Wireless Power Consortium), and input power is 5 W to the operating frequency of 155 kHz. In perfectly aligned condition, the max leakage magnetic field is 257.58 μ T which is obtained at the side of the device, and it is exceeded about 7.4 times of the ICNIRP 1998 reference level. The SAR is evaluated with homogeneous phantom which has electric constants of wet skin. The max value of the SAR is 134.47 μ W/kg which is obtained at the side of the device also, and it is much lower than the international guidelines. Especially, it showed higher SAR values in case of misalignment condition, so we will need to consider the misalignment condition importantly when we evaluate human effects for wireless power transfer system.


Author Institution: Institute of Physics, National Academy of Sciences of Ukraine; Institute of Low Temperature and Structure Research of the Polish Academy of Sciences, National Academy of Sciences of Ukraine


As the society is changing, so is aesthetic education. Modern aesthetic education should keep up with the times in order to adapt itself to the changing demand of society and human beings. It should not only keep vividness, emotionalness and gradualness of its traditional aesthetic education but also change its form into free aesthetic education and developing aesthetic education. Modern aesthetic education in various ways, individuation and high taste should be used to raise the appreciating level, spread the national spirit, optimize modern personality and promote the development of people's freedom.


Purpose: In a recent effectiveness trial of rabeprazole 20 mg once daily in over 2500 patients with endoscopically confirmed erosive esophagitis, we used the Medical Outcomes Study Short Form 36 (SF 36) to assess health related quality of life (HRQL) and the degree of impairment in HRQL relative to the US norm. The objective: to extend results from previous studies on HRQL impairment in GERD to an erosive GERD sample larger and more representative of this subset of GERD sufferers in the US population.


Edong Changjiang River Bridge is a hybrid girder cable-stayed bridge with a main span 926 m.The joint sections of the hybrid girder of the Bridge take the structural form of rear bearing steel plates with cells and the steel and concrete girders at the joint sections are connected by welded studs and perforated plate connectors.To investigate the force distribution and the sharing proportion of internal force of the connectors and also to check the arrangement of the connectors,a spatial finite element model is established for the local cells of the joint sections to analyze the mechanical behavior of the cells in consideration of the action of relative slip,bearing contact and connectors.The results of the analysis show that the connectors and bearing plates respectively share approximately 50% of axial compression force.The maximum shear force of the welded stud action is about 40 kN,of the perforated plate connectors is about 130 kN and the force transmitting of the connectors is obvious.Along the direction of the main girder axis,the stress in the cells gently decreases,the axial compression force of concrete linearly increases,the stress transition at the joint sections is smooth and the results of the calculation agree fairly well with those of the model test.


The development of array induction logging technologies both at home and abroad is introduced in this paper,including array induction imager tool in Schlumberger company,high definition induction log in Baker Atlas company,high resolution array induction tool in Halliburton company.Matrix induction tool in China is mainly made in Petroleum Logging.


This paper treats for automotive application the trade‐off between power saving and visual quality enhancement at one side and logic complexity as well as processing speed of local dimming processor at the other side. A key parameter is the resolution of an image condensed which is effectively the input image for the LED optimization. A higher number of condensation cells allows a more detailed consideration of the image given and the shape of the light spread function (LSF) of an LED. On the other hand, more memories are needed, and the processing steps are increased. The number of condensations cells are varied for 3 backlight units (BLU) with 133, 240 and 384 LEDs for a standard automotive display size of 12.3 inches. Power saving rate for a set of automotive HMIs as well as contrast enhancement are calculated. A recommendation for the resolution of image condensation in dependence of the LED resolution of the BLU will be given.


Treatment of triple-negative breast cancer (TNBC) is challenging because of its "COLD" tumor immunosuppressive microenvironment (TIME). Here, we present a hydrogel-mediated localized delivery of a combination of docetaxel (DTX) and carboplatin (CPT) (called DTX-CPT-Gel therapy) that ensured enhanced anticancer effect and tumor regression on multiple murine syngeneic and xenograft tumor models. DTX-CPT-Gel therapy modulated the TIME by an increase of antitumorigenic M1 macrophages, attenuation of myeloid-derived suppressor cells, and increase of granzyme B+CD8+ T cells. DTX-CPT-Gel therapy elevated ceramide levels in tumor tissues that activated the protein kinase R (PKR)–like endoplasmic reticulum kinase (PERK)–mediated unfolded protein response (UPR). This UPR-mediated activation of apoptotic cell death led to release of damage-associated molecular patterns, thereby activating the immunogenic cell death that could even clear the metastatic tumors. This study provides a promising hydrogel-mediated platform for DTX-CPT therapy that induces tumor regression and effective immune modulation and, therefore, can be explored further for treatment of TNBC.


The intelligent control systems have a success many years ago in lot of applications. Here is an application of fuzzy control and neurofuzzy in wastewater treatment plant (WWTP), in aeration basin. The advantages of using intelligent control are presented.


The teaching supervision system will have to be put in practice in colleges and universities with the reform of higher education system.It is very useful and necessary to improve teaching quality and to cultivate students with ability.We must think about how to consummate the teaching supervision system and how to improve supervision efficiency,etc.


We investigate the frequency of complete sets for t•ar·ious complexity classes within EXP under several polynomial-time reductions in the sense of resource bounded measure. We show that these sets are scarce: • The A key ingredient is the Small Span Theorem, which states that for any set A in EXP at least one of its lower span {i.e., the sets that reduce to A) or its upper span (i.e., the sets that A reduces to) has p 2 -measure zero. Previous to our work, the theorem was only known to hold for :'.Shu -reductions. We establish it for :=;~ 0 <,>-tt-reductions.


A micro lancet needle of 623 µm in length, 203 µm in width, and 106 µm in thickness was analyzed and fabricated with ANSYSY software and LIGA-like process. Biodegradable polylactic acid (PLA) was used as molding material. Taguchi method was utilized in the experiment to study the effects of molding parameters on the stiffness of the microneedle. Results showed that melt temperature has the most significant effects on the strength of the PLA microneedles. This study also demonstrates LIGA-like and micromolding techniques can be applied for mass replication of microneedles.


Globally, as in South Africa, obstetric hemorrhage (OH) remains a leading cause of maternal mortality and morbidity. Although blood transfusion is critical to OH management, the incidence and predictors of transfusion as well as their relation to human immunodeficiency virus (HIV) infection are poorly described.


Father involvement, as specifically parent-led or engaged activities, is recognized and understood as distinctively broad in scope, but also rigid and historically prescribed by gendered social roles such the provider and protector roles. American fatherhood is rooted in masculine tropes that historically restricted men to narrowly circumscribed social roles and expected parental performance. All too frequently hegemonic masculinity stifles broad paternal engagement and ingenuity as well as children's and families well-being. In addition, racial and ethnic bias and discrimination limits Black and other men of color's ability and access to enact paternal expectations and obligations broadly shared by American civil society and the fathers themselves (Johnson & Johnson, under review). Interventions with these fathers and their families frame the empirical studies in this Special Issue of Research on Social Work Practice.


The purpose of this study was to analyze the changes in muscle fatigue by using electromyography (EMG) measurements of the median frequency of shoulder muscles of patients who underwent rotator cuff repair, and to provide basic data for efficient exercise methods during rehabilitation after the repair. In the study, 24 male and 8 female patients who underwent rotator cuff repair performed continuous passive shoulder joint motion for 3 weeks and the median frequency of their shoulder muscles before and after the repair were compared using measurements by EMG. The infraspinatus, supraspinatus, and serratus anterior muscles showed significant differences in the changes in the median frequency before and after the repair. Significant differences were also found in the median frequency of the three muscles both before and after the repair. Additionally, the middle deltoid muscle had a lower median frequency than the supraspinatus muscle before the repair and the infraspinatus muscle had a lower median frequency than the middle deltoid muscle after the repair. It is expected that these results will serve as important data in developing rehabilitation exercise programs for the infraspinatus, supraspinatus, and serratus anterior muscles by compensating the middle deltoid muscle with the lowest muscle fatigue after the rotator cuff repair erase.


The article describes the main features of accounting and development of accounting in the hotel business during the transition to a digital economy. Considering the use of digital programs and applications, recommendations are given for improving accounting. The hotel industry is a key player in international tourism, and tourism flows depend on the quality of the tourism industry sector. The Republic of Kazakhstan is famous for its rich natural and tourist resources, but it occupies a small segment in the world tourism development. The main differences in the work of different hotels and hotels on the example of Kazakhstan and hotels in other countries are reviewed and summarized. In connection with the various services provided in hotels, it is necessary not only to monitor the quality of service and monitor the work of the staff but also to keep records of all possible expenses. In this regard, the cost of hotel business management. The paper discusses examples of automated systems to improve performance and accounting in hotels.


Excavations in and about the Palace of Nestor, which was discovered in 1939 at Epano Englianos in Southern Triphylia, were resumed by the archaeological expedition of the University of Cincinnati during the summer of 1957 in a sixth campaign, extending from May 21 to 3 August. As noted in earlier preliminary reports,' this enterprise represents the current American share in a joint HellenoAmerican archaeological investigation of Western Messenia, in which Professor Spyridon Marinatos of the University of Athens is my colleague. Once again Professor and Mrs. W. T. Semple of Cincinnati made the undertaking possible by providing the expedition in generous measure with the funds required. We are much beholden to Dr. J. L. Caskey, Director of the American School of Classical Studies at Athens, for many courtesies: he was especially helpful in lending to us for a few days his architect, Lloyd Cotsen, who came to Pylos and brought the plan of the palace up to date by adding the new wing that we uncovered during the season (pl. 38, fig. i). We likewise acknowledge our great obligation to Miss Alison Frantz, who photographed for us all the inscribed tablets, the seal impressions, and the seal stones found this year. We are also deeply indebted to Professor Marinatos, Director of the Greek Archaeological Service, for his assistance in having assigned to us a vasemender, Costas Pavlatos, for the month of July. The staff of the expedition comprised Miss Marion Rawson of Cincinnati, Professor Mabel Lang of Bryn Mawr, Lord William Taylour, and William P. Donovan. Dr. J. Lawrence Angel of the Jefferson Medical College spent some days with us-from July Io to 22-studying the skulls and the skeletal material recovered in 1956 and I957. It is a great pleasure in behalf of the expedition to express cordial thanks to all these colleagues for their faithful and indispensable cooperation. Dionysios Androutsakis of Chora, as in previous years, was our foreman, and our workmen, ranging from 14 to 30 in number, were for the most part trained veterans of earlier campaigns. Apart from our main preoccupation with the palace itself, we extended our activities to the investigation of tombs in the immediate neighborhood. On the palace ground exploratory trenches revealed walls of a hitherto unsuspected wing lying to the northeast of the enclosed courts outside the bath and the Queen's apartments. The structure, which was cleared in the course of the season under the direction of Marion Rawson, occupies a space ca. 32.50 m. long from southeast to northwest and


In recent decades, an increasing amount of attention has been paid to the interaction between Victorian literature and music. No critical work of consequence, however, has been written regarding Oscar Wilde, who is not popularly perceived as an artist with strong connections to music. It is a biographical fact that Wilde was neither a musician, nor an ardent worshipper of music like his contemporaries, Arthur Symons and George Bernard Shaw. Nevertheless, Wilde's belief that music is the perfect art form recurs in his writings, which contain multiple references to musical culture in the late nineteenth century. This paper broadly investigates Wilde's relationship to music in terms of biographical information, in the context of his aesthetic beliefs, and within the cultural framework of his time. It examines the writer's treatment of music both as a cultural phenomenon and as an idea, in order to highlight this neglected but important aspect of his work. Chapter One surveys biographical accounts which indicate the relevance of music in the life of Wilde, and traces how his intellectual appreciation of the art is represented both in his fictional characters and in his critical writings. The second chapter shifts its focus to Wilde's depiction of the state of music in late-Victorian England, by considering his appreciation of a number of renowned musicians and their work, particularly of Frédéric François Chopin and Richard Wagner. As the paper will show, the relevance of music to Wilde's writings exceeds the interest of an aficionado, and the manner in which he engages with music as an idea, together with his use of music to sketch the contemporary cultural scene, are a crucial aspect of his oeuvre.


The benefits of GNSS have created dependencies on navigation in modern day aviation systems. Many of these systems operate with no backup navigation source. This makes the capabilities supported by precise navigation vulnerable. This paper investigates a contemporary approach to terrain-referenced navigation (TRN), used to preserve an aircraft's navigation solution during periods of GNSS denial. Traditionally, TRN has been accomplished using a single measurement sensor pointed nadir to an aircraft. Although shown to be effective, this approach limits the achievable navigation accuracy by restricting the measurable terrain gradients to those below an aircraft. This paper explores an alternative approach to TRN that maximizes navigation information through optimal steering of a gimbaled laser. A Cramer-Rao lower bound analysis as well as a high-fidelity simulation establishes the utility of optimal steering while employing TRN. This original approach to TRN shows the order of magnitude improvements in navigation performance over existing methods.


Objective To study the effects and side effects of FK506 in renal transplant recipients. Methods 50 renal transplant recipients on FK506 were reviewed,in 40 of them FK506 being used immediately after transplantation and in 10 being converted from CsA to FK506 because of hepatoxicity.50 renal transplant recipients on CsA served as controls. Results In the CsA group,the renal function became normal in 2~26 days in 38 patients (76.0%).Acute rejection occurred in 9(18%),of them the renal function recovered in 8.Pulmonary infection occurred in 2,urinary infection in 1,renotoxicity in 2,hepatotoxicity in 3 (another 10 cases converted to the use of FK506 because of hepatotoxicity),hyperglycosemia in 2 and diarrhea in 1.Resection of the renal allograft was carried out in 1.In the FK506 group,the renal function became normal in 2~13 days in 40 patients(80.0%).Acute rejection occurred in 4,being all recovered on appropriate management,hyperglycosemia occurred in 14(28.0%),renotoxicity in 2,hepatotoxicity in 1 and diarrhea in 22(44.0%),In 1 patient,FK506 was conyerted back to CsA because of pulmonay infection and uncontrollble hyperglycosemia.In the 10 cases converted form CsA to FK506 bbecause of hepatotoxicity,the hepatic function recovered to normal in 7~16 days in all. Conclusions The use of FK506 is safe and effective in renal trnsplant recipients with less side effects.Its effects in long term survivals should be further studied.


We document the isolation and characterization of 27 microsatellite DNA markers for nutria, or coypu (Myocastor coypus), an invasive rodent introduced to North America as a domestic furbearer. Markers revealed moderate levels of diversity (averaging 5.0 alleles/locus) and heterozygosity (averaging 46%). Genotypic frequencies at 25 of 27 (93%) markers conformed to Hardy–Weinberg equilibrium expectations and no linkage disequilibrium was observed in a M. coypus collection (N = 64) from Maryland, USA. We believe this suite of markers to yield sufficient diversity to resolve patterns of effective migration among subpopulations, breeding structure, and demographics. This information can be instrumental to eradication programs that attempt to prevent recolonization among subpopulations.


Background: Infant feeding practices are the major determinants of nutritional status of infants and young children. Present study was undertaken to compare the infant feeding practices of rural and urban mothers and the factors influencing these practices. Methods: An observational study was carried out in department of Paediatrics, C R Gardi hospital (CRGH) associated with R D Gardi Medical College (RDGMC), Ujjain Charitable Trust Hospital (UCTH), a unit of C R Gardi Hospital and urban health centre, associated with R D Gardi Medical College, Ujjain. The present study included a total of 1000 children of which 500 were from rural and 500 from urban background over a period of one year. Information on breast feeding and complementary feeding practices was recorded. Results: In the present study, maximum children in both rural and urban areas were between age group of 12-36 months and majority of children of rural area were males. Significantly higher proportion of rural mothers was labourer, illiterate and belongs to low socioeconomic status groups. Majority of rural mothers discarded colostrums and offered prelacteal feeds to their babies. Significantly higher proportion of urban mothers started early initiation of breast feeding after delivery. Formula milk feeding was commoner in urban babies but bottle feeding was significantly higher in rural babies. Conclusion: Feeding practices are poor in rural area so mothers should receive counselling regarding early initiation, colostrum feeding and appropriate complementary feeding practices. Steps should be taken to improve the educational status of females especially among rural mothers.


The NCAA and its member schools are a joint venture that fixes the compensation of its most important workers, the athletes, at a level that is substantially below what would otherwise occur in a competitive market. Claims of amateurism and the need for competitive balance obscure the more than $3.5 billion dollars in revenue generated mostly on the backs of those athletes. From the point of view of rule of reason antitrust analysis, the NCAA's justification for its concerted wage fixing has obvious weaknesses. Recent phenomenal growth in revenue has made the claims of the necessity and reasonableness of concerted action to restrain wages increasingly dubious.


Redundancy is a feature of systems that arises by design or as an accidental byproduct of design, and can be used to detect, diagnose or correct errors that occur in systems operations. While it is usually investigated in the context of fault tolerance, one can argue that it is in fact an intrinsic feature of a system that can be analyzed on its own without reference to any fault tolerance capability. In this paper, we submit three alternative views of redundancy, which we propose to analyze to gain a better understanding of redundancy; we also explore means to use this understanding to enhance the design of fault tolerant systems.


To THE ACCOMPANIMENT of much healthy self-criticism the development of aptitude tests has gone on apace during the past three years. The literature for the period contains over two hundred titles on aptitude tests for many lines of endeavor—advertising designers, engineering apprentices, book revisers, dentists, dressmakers, executives, modistes, policemen, salesmen, shoemakers, surveyors, teachers, weavers, and others. The largest number is reported in the German journals, followed by those of the United States and England. Also represented are France, Italy, Russia, Spain, Australia, Argentina, and Japan. The line between aptitude and achievement tests is always a thinly drawn one. Sections of many of the tests mentioned above are out-and-out trade tests. A general characteristic is the absence of published validity coefficients. In an aptitude test this lack is far more serious than the general lack of published reliability coefficients, shown by Woody (478) to be characteristic of most published tests. Reliability can be had cheaply, usually, by simply lengthening a test. Validity responds but little to lengthening. Some articles report impressive validities based upon less than twenty cases. Rare indeed is the study which tells of an aptitude test having been validated upon some group other than the experimental group employed to determine the selection, weighting, or scaling of tests and items. Apparently most aptitude tests die aborning.


Hazards of earthquake to highway and bridge are analyzed. The quakeproof principle of highway and bridge in plain and mountain areas are put forward.


available at http://www.ncbi.nlm.nih.gov/pubmed/30217744 Re: Comparison of Clinical Outcomes of Prostatic Artery Embolization with 50-mm plus 100-mm Polyvinyl Alcohol (PVA) Particles versus 100-mm PVA Particles Alone: A Prospective Randomized Trial M. Q. Wang, J. L. Zhang, H. N. Xin, K. Yuan, J. Yan, Y. Wang, G. D. Zhang and J. X. Fu Department of Interventional Radiology, Chinese PLA General Hospital, Beijing, P.R. China J Vasc Interv Radiol 2018; 29: 1694e1702. doi: 10.1016/j.jvir.2018.06.019 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/30297313available at http://www.ncbi.nlm.nih.gov/pubmed/30297313 Editorial Comment: One always wonders why certain data sets don't seem to make sense. When study reports are consistently inconsistent among different investigators, we are left with more questions than answers. Reviewing the various reports on prostatic artery embolization (PAE) provides a textbook example of wide swings in data sets. For example in the study reported by Bhatia et al, an experienced group dedicated to the technology, the internal consistency is historically off base. In a group of men with baseline prostate volumes greater than 80 gm the improvement in International Prostate Symptom Score (67%) and prostate volume reduction (-39%) is transurethral prostatectomy-like. Serum prostate specific antigen (PSA) has an almost historical reduction (-70%). That's the good news! However, the improvement in peak flow rate of about 5 ml per second is more consistent with minimally invasive technologies (UroLift /Rez um ). Why? It makes little sense that such a magnitude of reduction in prostate volume and its proxy PSA is incongruous with the expected objective results. Furthermore, the authors note that despite such an impressive degree of volume reduction, there was no new onset of ejaculatory dysfunction. Wow! Wang et al, who cite their experience comparing 2 different polyvinyl alcohols, describe a dissimilar excrescent. Decrease in symptoms (75%) and increase in peak urinary flow rate (133%) are open prostatectomy-like. Yet despite a prostate volume reduction of more than 50%, serum PSA is decreased by only 27%, similar to results with finasteride and dutasteride. This wide intrastudy and interstudy variability makes it difficult to analytically and critically evaluate the data in a dispassionate manner. The bottom line is that PAE has a role in refractory prostate bleeding. Moreover, there are patients who have improvement in symptoms after treatment. However, until well developed clinical trials are done and these widely disparate data quirks are sorted out, PAE should be viewed as an investigative therapy. To paraphrase Johnnie Cochrane, if the data don't fit, the technology eventually gonna quit. Steven A. Kaplan, MD 0022-5347/19/2025-0001/0 THE JOURNAL OF UROLOGY 2019 by AMERICAN UROLOGICAL ASSOCIATION EDUCATION AND RESEARCH, INC. https://doi.org/10.1097/JU.0000000000000489 Vol. 202, 1-4, November 2019 Printed in U.S.A. www.auajournals.org/jurology j 1


Web browsers are one of the most pervasive applications for an entire range of personal computing platforms--from mobile devices to desktops. Using Web technologies (HTML, CSS, JavaScript) to build "Web apps" has the promise of creating portable applications for all platforms. Thus browsers become application containers, requiring increased performance from browser engines. Here, the authors discuss advances in browser technologies that exploit multicore processing. They use the Zoomm browser and the MuscalietJS JavaScript engine as running examples of highly concurrent Web browser and JavaScript engines. They show how concurrency is effectively exploited at different levels: to speed up computation performance, preload network resources, and preprocess resources outside the critical path to speed up page loading and Web workloads.


Reaction of acetyl chloride with [Pt(Cl2Fc)(CH3)(bipy)], where Cl2Fc and bipy are 1,1′-dichloroferrocen-2-yl and 2,2′-bipyridine, respectively, results in the trans oxidative-addition of the acetyl chloride to the PtII precursor to give the PtIV title compound, i.e. [Pt(CH3)(C2H3O)(C10H7Cl2Fe)Cl(C10H8N2)]. The three Pt—C bonds in the title compound are in a fac-configuration and range in length from 2.018 (12) to 2.079 (11) A. The chloro substituents of the ferrocenyl unit are in an eclipsed conformation.


In this paper we describe a virtual ultrasound imaging system for the simulation of ultrasound guided needle insertion procedures, which is designed to improve the early training stages of interventional radiology trainees. A pair of calibrated magnetic 3D motion sensors are used to capture the position and orientation of a mock ultrasound probe and needle, whilst emulational ultrasound images are generated in real-time from a labelled volumetric data set that is non-rigidly aligned to a physical model of human body. To achieve a realistic simulation of ultrasound imaging, a set of volumetric textures are constructed to represent the typical appearance of ultrasound images, and an alpha blending method is applied to produce the radial blurring effect. The procedures of volumetric registration, sensor calibration, construction of texture bank, and image rendering, are presented.


This study examines differences in demographic characteristics and HIV-related risk behaviors between Chinese female heroin users who exchanged sex for drugs or money and those who were never involved in sex exchange. A sample of 171 female heroin users was recruited from a detoxification center in China. Female heroin users who exchanged sex for drugs or money were more likely to be unemployed and were at higher risk in both sexual behaviors and injection drug use. Number of sexual partners in the previous year, unemployment, and injection drug use were independently associated with exchange of sex for drugs or money; adjusted odds ratios were 1.2, 3.8, and 2.6, respectively. Findings show that HIV-related risk behaviors are common among female heroin users in China and that HIV harm reduction should be focused on female heroin users who exchange sex for drugs or money.


In this paper, a simple wideband unidirectional antenna is proposed. The antenna is originated from the basic magneto‐electric (ME) dipole antenna. A pair of half‐wavelength horizontal patches are used to excite the basic electric dipole mode. In order to excite the basic magnetic dipole mode, the horizontal patches are extended inward. As a result, the quarter‐wavelength vertical patches are well excited and the impedance matching is improved in the high frequency band. In addition, a pair of vertical patches are employed, it can not only reduce the resonant frequency of the basic electric dipole mode but also form a new magnetic dipole mode at low‐end frequency. Therefore, the impedance matching in the low frequency band is further improved. The proposed antenna is fabricated and measured. A wide bandwidth of 100% from 2.0 to 6.0 GHz for VSWR <1.5 is obtained. Across the entire bandwidth, the gain is 5.6 ± 1.3 dBi, the front‐to‐back ratio (FBR) is >10 dB. Moreover, the radiation patterns are stable, symmetrical, and have no side lobe. The proposed antenna is suitable for wideband unidirectional wireless systems.


Contrary to the existence of a well-developed literature on paradiplomacy3, there is a rather small, limited, but hopefully emerging, literature on parliamentary diplomacy. As with paradiplomacy ( parallel diplomacy ), the mere qualification of the term diplomacy conveys the view that there must be something strange, different, or weird ; something that a priori should not be there, that should not exist. But (similarly to paradiplomacy) facts simply do not follow the expectations that past experience might have created. In the past, the traditional international state system implied that states were the sole actors worth studying, and that the Executive was the only important actors in foreign policy. A dominance that a variety of factors and actors have challenged, with regions and parliaments as only two of such challenges (e.g. growth of economics, civil society, transnational actors a-la NGOs, multinational firms, terrorist organisations – of course, not all challenges are legitimate ones).


Today, Internet service providers and enterprise networks are facing rapid changes and growing rapidly, and network operations become complex to support these demanding applications. In traditional IP/MPLS networks, the operation becomes complex because of complicated traffic engineering configurations. Service providers and enterprises are demanding more scalable, flexible, and programmable solutions to keep up with the rapidly changing demand to support demanding applications. Segment Routing (SR) is a source routing technology which helps overcome the traditional IP/MPLS networks' drawbacks in scalability, flexibility, and applicability in Software-Defined Networking (SDN). This paper will present how we can implement SR-TE tunnels from Pathman-SR [9] running on top of the OpenDaylight SDN controller. We will also present how we can see the whole view of network topology that Pathman-SR can provide and program SR-TE tunnel from the SDN controller.


Polycarbonate exposed to sunlight yellows, degrades and loses its usable properties. In order to increase its lifetime, it can be coated with nano-ceramic thin layers of ZnO and Al2O3 deposited by sputtering. The role of the ZnO is to absorb the UV photons that can damageable for the polycarbonate. However, one of the limitations in the use of ZnO is the photocatalytic oxidation that could occur at interface ZnO/PC as a consequence of the photocatalytic activity of this oxide. Insertion of Al2O3 between PC and ZnO could be a way to inhibit this interfacial oxidation. The photooxidation of the ceramic/polymer assemblies, in condition of artificial accelerated ageing, was measured by infra-red and UV-vis spectroscopies. The results show that the photocatalytic activity of ZnO occurring in monolayer coated substrates can be significantly reduced by insertion of Al2O3 and that, in addition, Al2O3 decreases the permeability to oxygen of the coating.


The intricate interplay between the microscopic constituents and their macroscopic properties for masonry structures complicates their failure analysis modelling. A composite strategy incorporating neural network (NN) and cellular automata (CA) is developed to predict the failure load for masonry panels with and without openings subjected to lateral loadings. The discretized panels are modelled by the CA methodology using nine neighbour cells, which derive their state values from geometric parameters and opening location placement for the panels. An identification coefficient dictated by these geometric parameters and experimental data is fed together as the input training data for the NN. The NN uses a backpropagation algorithm and two hidden layers with sigmoid activation functions to predict failure loads. This method achieves greater accuracy in prediction when compared with the yield line and finite elemental analysis (FEA) methods. The results attained elucidate the feasibility of the current methodology to complement conventional approaches such as FEA to provide additional insight into the failure mechanism of masonry panels under varied loading conditions.


Provided is a bending tool for electric heating pipes, relating to a tool which can bend arc electric heating pipes at will, comprising a work bench (1), a cylinder mould (3), a first grip block (4), a second grip block (5), a deflector (7), a baffle plate (8), a support body (9) and a bushing (10). The cylinder mould (3) is in fixed connection on the work bench (1); the work bench (1) on one side of the cylinder mould (3) is provided with a sliver hole (6); the first grip block (4) and the second grip block (5) are installed on the sliver hole(6) through bolts. One side of the work bench (1) is fixedly connected with the deflector (7), one side of which is fixedly connected with the baffle plate (8); the bushing (10) with an end face fixedly connected with the support body (9) is sleeved on an electric heating pipe to be processed. The bending tool for electric heating pipes of the utility model is time-saving and labor-saving, and can bend with unified effects and agonic shapes.


Naturally, these issues are of great interest not only to actors in the banking market but also to central banks and other regulators of the financial market. As we share experiences and engage in open discussions, we will be able to identify far-reaching approaches that are best fitted to meet the challenges ahead. We have invited distinguished speakers and experts from renowned international institutions as well as other actors and regulators from Albania and the region.


By using crystalline electric field model, the spin reorientation phenomena of Tm 2Fe 17-x Ga x Compounds is analysed in this paper. We calculate spin reorientation temperature values of these compounds and compare them with experimental data. The 4f 3d exchange energies are also obtained by calculation. The effect of Ga concentration on B m n is discussed.


A method is presented to measure the microheterogeneity of ferritin in μg amounts, without purifying the samples extensively. Ferritin-containing samples such as serum and homogenized liver-biopsy specimens were mixed with Sephadex G-75 and ampholines. Isoelectric focussing was performed and the pH gradient in the Sephadex was measured. The Sephadex was divided into predetermined pH ranges and the ferritin eluted from these fractions. Ferritin concentration was measured by an enzyme-linked immunosorbent assay. The method proved to be reproducible. The isoferritin profiles of different human serum and liver tissue samples were quite variable. In most cases serum ferritins focussed between approximately pH 5·5 and pH 4·9 and liver ferritins between approximately pH 5·8 and pH 5·3. We examined whether there was a similarity in the isoferritin patterns of serum and liver of distinct patients. We also studied liver tissue and serum from a patient with haemochromatosis and from a child with iron overload of unknown origin. In the serum of our patients the isoferritin pattern had shifted to lower pI when compared with that found in liver tissue. Only in the case of a patient with transfusion iron overload were basic isoferritins measured in the serum. In this case no liver biopsy specimen was available for comparison.


Herein, one dimensional copper-nickel sulfide nanowires (NWs) were, for the first time, synthesized by using an accurate one-pot multi-step wet chemistry strategy. The obtained copper-nickel sulfide NW electrocatalysts exhibit superb performance for both the hydrogen evolution reaction and oxygen evolution reaction, which is mainly due to the active centers Cu2S, NiS and Ni3S2.


Cupressus sempervirens var. is a plant rich in bioactive compounds and it has been a typical used in folk medicine for thousands of years. In Algeria, Cupressus sempervirens is widely used as traditional remedies for treatment of different complicate infectious diseases this study was conducted to evaluate antibacterial properties of ethyl acetate extracts of Cupressus sempervirens against gram negative and gram positive. The plant was collected from Chlef, in Tenes is a region of Algeria Mediterranean, then, the plant extract was prepared by maceration .The antibacterial activity of the extracts was investigated against 6 clinical and reference strains based on two assays: the well diffusion method and the agar dilution method. Cuperssus sempervirence acted as the agent antibacterial by having the highest (MIC/MBC 0.25v/v) against B.subtilis ATCC 6133, E.coli followed by Coagulase-Negative Staphylococci, Microccocus lutea (MIC/MBC 0.5v/v). Results of the phytochemical studies of ethyl acetate extract revealed the presence low amount of total phenolic according to the spectrophotometric method. Cupressus sempervirens has broad spectrum antibacterial activity and can be consider as a potential source of new classes of antibiotics that could be useful for infectious disease chemotherapy and control.


Today's schools are challenged to the problem-solving of many situations, v.g. multiculturalism or inclusion of students with special educational needs, which call for the implementation of distinct practices, based on cooperation and inclusive differentiation, that will contribute to significant apprenticeships. Schools are a privileged place for the interaction of policies, of cultures and of practices. We therefore consider of utmost importance to ponder over the effectiveness of implementing activities to the facilitation of said interaction and to a significant bearing of inclusion. The findings of the research we have been carrying out, some of which are present in this article, as well as the practice in which we have been involved, show how training based on the analysis of needs is an excellent contribution to examining these and other questions aroused by the inclusion these students.


INTRODUCTION The genus Salvia (fam. Labiatae) is one of the largest genera of flowering plants, with nearly 1,000 species from both the Old and New World, largely cultivated for ornamental, aromatic and culinary usage. The genus exhibits a remarkable range of morphological and ecological variation and poses numerous problems for the taxonomist and evolutionary biologist. The introduction of DNA-based analysis has provided many useful markers for genetic fingerprinting in order to study genetic diversity and to characterize unknown accessions. In the range of DNA-profiling methods, the RAPD (Random Amplified Polymorphic DNA) technique has been widely used for its simplicity in procedures, use of random arbitrary primers, costeffectiveness, and the requirement of minute quantities of DNA. In the framework of an European INTERREG ALCOTRA Project "SALVIE", for the valorisation of new germplasm, we have used RAPD analysis to determine the genetic relationships among several sage genotypes of the collection of 150 sage accessions, established at C.R.A.Experimental Institute for Floriculture in Sanremo (ITALY). PLANT MATERIAL Seventeen accessions of sage were analysed: they included 12 different species, 4 cultivars and one hybrid (Table 1).


Author(s): Ji, F; Navarro, JG; Musumeci, P; Durham, DB; Minor, AM; Filippetto, D | Abstract: © 2019 authors. Published by the American Physical Society. Precise manipulation of high brightness electron beams requires detailed knowledge of the particle phase space shape and evolution. As ultrafast electron pulses become brighter, new operational regimes become accessible with emittance values in the picometer range, with enormous impact on potential scientific applications. Here we present a new characterization method for such beams and demonstrate experimentally its ability to reconstruct the 4D transverse beam matrix of strongly correlated electron beams with subnanometer emittance and submicrometer spot size, produced with the HiRES beamline at Lawrence Berkeley National Laboratory. Our work extends the reach of ultrafast electron accelerator diagnostics into picometer-range emittance values, opening the way to complex nanometer-scale electron beam manipulation techniques.


Background: Prospective magnetic resonance imaging (MRI) of orbits in healthy paediatric population is difficult as it involves sedation or general anaesthesia in most of the cases. The data of normal value of healthy paediatric optic nerve and optic nerve sheath diameter is also scant in literatures for Indian paediatric population. The normal data will help in defining abnormal optic nerve such as congenital optic nerve hypoplasia, optic nerve atrophy and distended optic nerve sheath in raised intracranial pressure. AIM: The aim of our retrospective study is to define the normal value of optic nerve and optic nerve sheath diameter in MRI of paediatric Indian population. Methods: 190 MRI studies of paediatric brain with normal radiology reports and no history of raised intracranial pressure were retrospectively reviewed by two senior radiologists using T2 weighted axial brain images. Results: The mean optic sheath diameter and optic nerve diameter of 380 eye balls were 4.746 and 2.59 mm respectively. The age wise distribution of optic sheath diameter and optic nerve diameter were 4.08±0.019, 2.05±0.608 in 0-2-year age group, 4.83±0.575, 2.54±0.456 in 3-6-year age group, 4.789±0.553, 2.704±0.447 in 7-12-year age group, and 4.82±0.567, 2.65±0.412 in 13-18 years age group in mean (mm)±standard deviations respectively. Three hundred seventy-one (97%) optic sheath measurement of the 380 eye balls was below the threshold of 6 mm and about 352 (92%) optic nerve measurements out of 380 globes were having optic nerve thickness above 2 mm. Conclusions : This normative data will help the ophthalmologist, clinician, neuro-ophthalmologist and radiologists for better quantitative evaluation of pediatric patient with vision abnormality.


We have investigated the effect of photoinduced electron transfer on the photoconductivity (PC) of conducting polymer-C 60 films by comparing the photoconductivity (carrier generation and carrier transport) of the conducting polymer sensitized with C 60 with that of the conducting polymer alone. We present time-resolved transient PC results, subnanosecond to 0.5 μs, obtained from poly[2-methoxy,5-(2'-ethyl-hexyloxy)-p-phenylene vinylene] (MEH-PPV) and poly(3-octylthiophene) (P3OT), and from conducting polymer films sensitized with several concentrations of C 60


OBJECTIVE: To investigate the relationship of early MRI measures of spinal cord (SC) lesions and atrophy with disability 5years after a clinically isolated syndrome (CIS).
BACKGROUND: SC pathology is an important substrate for long-term disability in people with multiple sclerosis (MS). Focal SC lesions and SC atrophy measured on MRI have been independently associated with disability in established MS. In the present study we investigate whether SC lesions and atrophy are related to disability in subjects who had developed MS 5 years after CIS.
DESIGN/METHODS: 121 patients (mean age 32.8years, 60[percnt] female, 114 non-spinal CIS) were seen within 3 months of CIS and followed for a mean of 5.3years. Brain and SC MRI was performed on a 1.5T scanner. SC lesions were identified by an experienced neuroradiologist from PD/T2-weighted sagittal images of the whole cord. Upper cervical cord cross-sectional area (UCCA) was measured using an active surface model from reformatted T1-volumetric cord images. MS was diagnosed using the 2010 McDonald criteria and disability measured using the Expanded Disability Status Scale (EDSS). Significant disability after 5years was defined as EDSS 蠅3.
RESULTS: When the MS group with significant disability (n=15) was compared with those without disability (n=69), there was a higher number of SC lesions at baseline (median 2vs0, p<0.01), in addition to more new SC lesions (median 5vs1, p<0.01) and greater SC atrophy (mean annualised change in UCCA -1.0695vs-0.3266mm2, p<0.01) over 5 years. In a multivariable linear regression model, baseline cord lesion number (coefficient=0.48, p<0.01), number of new cord lesions (coefficient=0.19, p<0.01) and change in UCCA (coefficient=-0.17, p<0.01) were associated with EDSS (R2=0.55). Including brain T2 lesion load and atrophy measures only modestly increased the predictive power of the model (R2=0.61).
CONCLUSIONS: SC lesions and atrophy detected on MRI may be an important determinant of MS-related disability 5years after CIS. Disclosure: Dr. Brownlee has nothing to disclose. Dr. Alves Da Mota has nothing to disclose. Dr. Padros has nothing to disclose. Dr. Swanton has nothing to disclose. Dr. Miszkiel has nothing to disclose. Dr. Altmann has received personal compensation for activities with Merck & Co., Inc. Dr. Ourselin has nothing to disclose. Dr. Wheeler-Kingshott has received personal compensation for activities with Biogen Idec as an advisory board member. Dr. Ciccarelli received personal compensation for activities with Novartis as a consultant. Prof. Miller has received honoraria through payments to his employer, UCL Institute of Neurology, for Advisory Committee and/or Consultancy advice in multiple sclerosis studies from Biogen Idec,;,


Despite a growing body of research about the Matthew Effect and status, we still know little about the cognitive biases that underlie the ability of high status actors to accumulate advantages over their lower status peers. In this paper we test the assumption that actors' status biases evaluators' judgments made about those actors' quality. We posit that high status actors benefit from over-recognition of quality, wherein evaluators are more likely to erroneously attribute high quality to an actor's performance, and that evaluators systematically and erroneously under-recognize quality in low status actors. Using unique data from Major League Baseball umpires' evaluation of pitch quality, which allow us to observe the difference in a pitch's objective quality and in its perceived quality as judged by the umpire, we show that umpires are more likely to over-recognize quality in high status pitchers and under-recognize quality in low status pitchers. Ambiguity and the pitcher's reputation as a " control pitcher " moderate the effect of status on umpire judgment. Further, we show that umpire errors resulting from status bias lead to actual performance differences, decreasing the probability that high status pitchers allow players to get on base and increasing the likelihood of winning the game. Authors in alphabetical order. We benefitted from helpful comments Sociologists have long understood status to be an indicator of hierarchical position and prestige that helps individuals and organizations procure resources and opportunities for advancement (e.g., Whyte 1943; Podolny 2001). Status markers, like ranking systems in education (Espeland and Sauder 2007) or All-Star selections in professional sports, accentuate quality differences among actors and create greater socioeconomic inequality. Research on status characteristics has advanced our understanding of how status hierarchies emerge and persist, and how status becomes associated with particular characteristics such as race and gender (Berger, Rosenholtz, and Zelditch 1980). In contrast, the question of how status hierarchies, once developed, lead to performance differences among individuals within that hierarchy has received relatively less attention in this literature. Variation in ultimate performance due to status differences is, of course, the central problem of interest in Merton's Matthew effect. Merton (1968) postulated that high status individuals experience performance advantages relative to their peers due to the increased recognition given to their high quality output, which consequently leads to more opportunities to excel and more resources that can be used to improve future performance. Despite ample evidence that actors experience differential rewards for …


A new method for the prediction of the viscosity of coal ash slags, in the Newtonian region, is presented. The technique is modeled on experimental viscosity data less than 1000 Pa s and hence is most reliable in that region. The capability of the model in predicting the viscosity of slags from coal ash was found to be superior to a number of the most commonly used empirical models found in the literature, which are based on simplified oxide melts or British coal ash slags. The method also provides an indication of the relative fluxing strength of the basic oxides usually found in coal ash slags. It was found that the fluxing strength is related to the inverse of the cation radius.


Ionosphere sounding is of significant importance for compensating ionospheric effects on satellite communication, navigation and remote sensing systems at lower frequency, i.e. L-band, P-band etc.. A novel spaceborne HF/VHF-radar scheme is proposed for ionosphere sounding. Based on Frequency Division (FD) technique, the mode for large-scale ionospheric structure sounding can generate a two-dimensional (2D) topside electron density image. Based on synthetic aperture technique, the mode for small-scale ionospheric irregularities imaging can generate a 3D irregularities image. The effectiveness of the proposed SAR system was verified by means of computer simulations. The simulation results show that the resolution of large-scale sounding mode is as high as 0.49km, and the resolution of small-scale sounding mode is as high as range 0.9km, azimuth 0.27km and across-track 0.25°.


The use of synchrotron radiation as the excitation source for total reflection x-ray fluorescence analysis (SR-TXRF) in combination with a multilayer structure for monochromatization led to detection limits in the femtogram range for medium-Z elements. Experiments were performed at the Hasylab Beamline L using bending magnet radiation. Different methods for the modification of the spectral distribution, viz. multilayer monochromatization, insertion of a high-energy cut-off and a simple filter technique, were compared. Also, several possible types of geometrical arrangement of the sample and detector were examined to establish whether an improvement in excitation or detection conditions is possible. Samples were of evaporated droplets of aqueous or acidic solutions of several elements at various concentrations. Spectra were evaluated and the data used to extrapolate the detection limits (DL). Monochromatization of the synchrotron radiation in combination with a sample carrier positioned in the vertical plane and a side-looking detector in the plane of polarization turned out to give the best results with a DL of 15 fg for Ni.


Three chitosan (CS), polyethylene glycol (PEG) and polylactic acid (PLA) nanocomposite systems containing SiO2 nanoparticles and water molecules were designed by molecular dynamics (MD) simulations to deliver pipobromane (PIP) anticancer drug in order to discover the most appropriate drug delivery system (DDS) in aqueous medium which was analogous to the human body. The density for the CS matrix was 1.25 g/cm3 but it was decreased to 1.16 g/cm3 in PLA and 1.02 g/cm3 in PEG. The potential energies of the CS, PLA and PEG DDSs were near 195000, 3700 and –4600 kcal/mol while their related non-bond energies were around 14000, –150 and –6150 kcal/mol, respectively, indicating the PEG composite had the most negative energies whereas the most positive values belonged to the CS system. The CS system revealed the greatest fractional free volume (FFV) of 77.232% but PLA offered the smallest FFV (65.804%). The radial distribution function (RDF) data displayed that the PIP molecules had strongest H-bond interactions with the CS chains which reflected the drug molecules would diffuse the slowest inside the CS nanocomposite. The diffusion coefficients for the PLA, PEG and CS systems were equal to 0.0183×10–4, 0.0163×10–4 and 0.0154×10–4 cm2/s, respectively approving the slowest drug diffusion was happened in the CS cell which certified the most controlled and sustained drug delivery.


INTRODUCTION AND OBJECTIVE:Adoption of prognostic molecular assays for prostate cancer (PCa) requires evidence of robust performance in different racial groups, especially in African Americans (AA)...


This study analyzes whether KIKO is appropriate in hedging the risk of the exchange rate changes. If so, KIKO should satisfy two conditions. First, the properties of the risk of the exchange rate changes should be accurately analyzed. Second, the instrument should be designed to hedge them. To evaluate them, we estimate the generalized Pareto distribution of the exchange rate changes. Also, we estimate the distribution function of the return profile of the hedged position in the maturity date by the stationary bootstrapping method. The results show that KIKO was designed upon the wrong assumptions about the distribution of the exchange rate changes. It ignores the extreme behaviors of the exchange rate changes, and the symmetry of them in the left and in the right tail. Because of its defects, KIKO cannot provide the good performances in hedging the risk of the exchange rate changes.


Huxian has implemented New Rural Cooperative Medical System since the beginning of year 2005. In order to find out farmers' cognitions and attitudes to New Cooperative Medical System after one year's implement and provide scientific basis for improving and perfecting New Rural Cooperative Medical System,Huxian Cooperative Management Office made a survey to 1978 farmers from 50 pilot administrative country in terms of awareness,attendance,evaluation of farmers to New Rural Cooperative Medical System,the understanding on reimbursement of outpatient and hospitalization expenses and the chosen of cooperative medical pilot hospital. This article analyzes the above-mentioned investigation report,points out the existing question in New Rural Cooperative Medical System and gives out advice on it.


A pair of asymmetrical electrodes under high voltage can produce an ionic wind and thrust. Ionic wind propulsion has been proposed as an alternative method to that used by standard airplanes today. The main advantages of the proposed aircraft propulsion are: no moving parts, nearly silent and no combustion emissions. This paper reports on experiments with two offset electrode configurations for the generation of thrust by corona discharges and shows scalability of thrust by increasing the thruster frame length from 0.4 m up to 4 m. A concept for an EAD biplane flying wing design is presented, with a wing span of 4 m and an expected thrust of 8.5 N.


Seven 5 arylidenebarbituric acids were synthesized by a solid phase condensation reaction of aromatic aldehyde with barbituric acid in the presence of ammonium acetate. The reactions could be completed in 5~8 min with 65%~93% yields.


Ochraroxicosa pigs shows that weight and size of the change depends on the amount taken ochratoxin . The emergence ochratoxicosis in growing pigs determined at slaughter and that the base altered kidney . Diagnosis is based on anamnesis , C linical sign , pathological and micotokoskology findings. . Normal 0 false false false EN-US X-NONE X-NONE


We see many developments in the vehicles and their transmission systems. These majorly focus on the latest market trends, user demands and better sophisticated technology. The transmission system developer must closely observe the market and the changing values in the society as the transmission system doesn't change in an overnight. They require sufficient time to get established and become stable in the market.The scope of the paper involves creating the control strategy for the working of the synchronizer for an AMT vehicle in MATLAB Simulink. In MATLAB Simulink a mathematical working model of the component is developed. The output of the model estimates the force of actuation and the time required during the shift process which predicts the actuator parameters, used further to operate the actuators. Once the mathematical model of control strategy is defined and its values are obtained, these can be implemented in the vehicle design model.


Optically pure (R)- and (S)-3-hydroxybutanoic acid and its homologues are prepared by the method consisting of the enantioface differentiating hydrogenation of methyl 3-oxoalkanoate to methyl 3-hydroxyalkanoate(80–90% e.e.) over asymmetrically modified nickel catalyst and the preferential crystallization of optically pure 3-hydroxyalkanoic acids from the hydrogenation products as the dibenzylammonium salts.


The invention can be used in the technical field of automobile control, and provides an electrical parking method and device. The electrical parking method includes: comparing a vehicle real-time gear direction displacement and a free displacement when a vehicle is in a parking state; calculating a parking torque command value according to a parking effective displacement and a current speed if the vehicle real-time gear direction displacement is greater than or equal to the free displacement; and outputting and controlling the current to be the parking torque command value. A suitable torque can be calculated in parking according to the displacement and the speed, a controller can control a motor to output the suitable current, and then the vehicle can steadily park on a ramp, and the problem that the vehicle shakes back and forth in parking can be overcome.


Many studies have focused on chronic kidney disease in HIV‐positive individuals, but few have studied the less frequent events, advanced renal disease (ARD) and end‐stage renal disease (ESRD). The aim of this study was to investigate incidence, predictors and outcomes for ARD/ESRD and renal death in EuroSIDA. ARD was defined as confirmed eGFR < 30 ml/min per 1.73 m2 (>3 months apart) using Cockcroft‐Gault. ESRD was defined as hemo‐ or peritoneal dialysis>1 month/renal transplant. Renal deaths were defined as renal failure as the underlying cause of death, using CoDe methodology. Patients were followed from baseline (first eGFR after 1/1/2004) until last eGFR, ARD/ESRD/renal death; whichever occurred first. Poisson regression was used to identify predictors. 8817 persons were included, the majority were white (87.3%), males (73.9%) infected though homosexual contact (41.5%) and with a median age of 42 years (IQR 36–49). 45 persons (0.5%) developed the composite endpoint; ARD (24), ESRD (19) and renal death (2) during a median follow up (FU) of 4.5 years (IQR 2.7–5.8), incidence rate (IR) 1.21/1000 PYFU (95% CI 0.86–1.57). Of 312 persons (3.5%) with baseline eGFR<60 ml/min/1.73 m2, 13.3% (7.5–18.9) are estimated to develop ARD/ESRD/renal death within 6 years after baseline compared to 0.86% (0.58–1.1) of all patients, using Kaplan‐Meier methods. Predictors in multivariate analysis were older age (IRR 1.29 per 10 years [0.95–1.75]) any cardiovascular risk (IRR 2.34 [1.23–4.45]), CD4 count (IRR 0.76 per 2‐fold higher [0.60–0.97]) and eGFR (IRR 0.63 per 5 ml/min/1.73 m2 higher [0.58–0.69]).


Due to the high importance of bioenergy in today's energy system and the vast potentials of biomass, scenarios for the future development of the bioenergy sector are of major interest. There are numerous factors which influence the medium to long-term prospects of bioenergy, including fossil fuel price developments, technological progress, energy demand trends and many more. Simulation tools are a means for handling the complexity of and interactions between these influencing factors and deriving well-founded scenarios. This work provides insight into the modelling approach of the simulation tool SimBioSys and presents exemplary simulation results for the development of the Austrian bioenergy sector up to 2030 in an ambitious support scenario. The simulation results include the share of biomass in the total energy consumption, the energy output broken down by technology groups, the achieved annual greenhouse gas mitigation and fossil fuel saving as well as cost analyses.


Objective To evaluate the clinical efficacy of vitrectomy using noncontact panoramic viewing systems for removal of intraocular foreign bodies.Methods Forty-eight injured eyes of 47 cases with intraocular foreign bodies(IOFBs) underwent vitrectomy using the noncontact panoramic viewing systems.Results The IOFBs were extracted successfully.Forty eyes were examined after 3-35 months,the visual acuity was improved in 38 eyes(95%) and not changed in 2 eyes(5%).Conclusions The vitrectomy and extraction of IOFBs using the noncontact panoramic viewing system is safe and effective for the injury eyes with intraocular foreign bodies.


This article examines the sociocultural, historical and ideological backgrounds surrounding the formation, maintenance and changes of 'Cheongnyangni 588', a representative red light district in Seoul, focusing especially on insiders' experiences. Adopting Low(1996)'s theoretical framework of the soc...


The objective of the circular economy is to definitively change the way in which we produce and consume, it consists of doing more with less, and it brings us back to simplicity, trying to break the dependence: production-consumption of raw materials, making the most of each material and extending its useful life. Through eco-design, it seeks to generate circular products that allow the easy separation of all materials, providing new ways of their management and processing to avoid elimination at the end of their useful life so that they can be recovered to start a new life, �closing the circle�. In this study, the carbon footprint generated by the materials and manufacturing processes of the classic shoe vs the "eco-engineered" version was analyzed. The type and source of the materials that make up the footwear are of major influence. Thus, a textile material obtained through recycling was chosen for the upper. The sole used to obtain the footwear product was recycled TPU. The carbon footprint was analyzed with LCA software, GaBi. The LCA was performed on the materials and process for each type of footwear. The Carbon footprint for the eco-engineered version presents values between 65-80% lower than the conventional version. These values depend on the type and amounts of materials and whether this footwear is repaired / recycled.


We investigate the enhancement of second-harmonic generation in cylindrical GaAs nanowires. Although these nanostructures confine light in two dimensions, power conversion efficiencies on the order of 10 − 5 with a pump peak intensity of ~ 1   GW / cm 2 are possible if the pump and the second-harmonic fields are coupled to the Mie-type resonances of the nanowire. We identify a large range of nanowire radii in which a double-resonance condition, i.e., both the pump and the second-harmonic fields excite normal modes of the nanowire, induces a high-quality-factor peak of conversion efficiency. We show that second-harmonic light can be scattered with large efficiency even if the second-harmonic photon energy is larger than 1.42 eV, i.e., the electronic bandgap of GaAs, above which the material is considered opaque. Finally, we evaluate the efficiency of one-photon absorption of second-harmonic light and find that resonant GaAs nanowires absorb second-harmonic light in the near-field region almost at the same rate at which they radiate second-harmonic light in the far-field region.


Photolystic kinetics of vinclozolin in various aqueous solutions under a high pressure mercury lamp and the sunlight were studied.The half-life of vinclozolin photolysis in redistilled water was 28 min and 3.86 h under a high pressure mercury lamp and the sunlight,respectively.Soluble substances in tap water and lake water showed faint influence on photodegradation of vinclozolin under the high pressure mercury lamp,but significant sensitizing effect under the sunlight,bringing the photosensitizing rate up to 138% and 126% in 3 h,respectively.Under either light sources,both buffers,pH 5.0 and pH 7.0,showed an obvious photoquenching effect on vinclozolin,but buffer pH 9.0 showed a strong photosensitizing effect,especially under the sunlight.The photoquenching rates of the buffers,pH 5.0 and pH 7.0,against vinclozolin were 69% and 57% under the high pressure mercury lamp for 60 min,respectively and 77% and 33% under the sunlight for 7 h,respectively.The photosensitizing rate of buffer pH 9.0 was 58% and 415% under the high pressure mercury lamp for 20 min and under the sunlight for 1 h,respectively.


Historical introduction, Michel Le Gall deconstruction and reconstruction - the second stage of state building in North Africa, El-Baki Hermassi and Dirk Vandewalle political parties in North Africa, Clement Henry Moore problems of urban youth - social mobilization, unrealized expectations and political alienation, Mark Tessler Islam and the state in North Africa, Mohammed Tozy demographic pressures and the dynamics of the rural system in North Africa, Hamid Ait Amara economic crisis and policy reform - North African development strategies in transition, Rhys Payne local societies in North Africa, Nicholas Hopkins the Arab Maghrib Union and the prospects for North African unity, Mary Jane Deeb the Maghrib states and the European Community - the dynamics of asymmetry, William Mark Habeeb the United States and North Africa, John Damis the Maghrib into the future, I. William Zartman.


In this paper, a new expression is provided for the rank of the space-time clutter covariance matrix when spatial subarrays are employed to combine the antenna array elements. The new results are applicable to subarrays that are overlapped, adjacent to one another, or separated with a gap in the underlying element structure. It is only assumed that the underlying element structure is uniform and that the subarrays are constructed in an identical fashion with uniform spacing. It is recognized that the case in which the subarrays are separated corresponds to a regularly spaced "sparse" collection of subarrays. Conditions are provided to indicate when the new expression is exact and when it is an upper bound. The situations where the new expression for clutter rank is exact correspond to new families of scenarios (beyond those previously described in the literature) in which the clutter rank "collapses" due to spatial aliasing. In situations where the new expression is an upper bound, simulations have shown that the new expression is significantly tighter than previously published results. It is expected that the reader may utilize these results to select system parameters to minimize the complexity of the clutter mitigation structure, for airborne or spaceborne radar applications.


In 2016, child maltreatment from abuse or neglect affected more than 600,000 children in the U.S. and resulted in more than 1700 deaths.To determine


We consider a one-dimensional supersymmetric t−J model and introduce a finite concentration of impurities of arbitrary spin S without destroying the integrability. Using the Bethe ansatz equations diagonalizing the correlated host with impurities, we discuss the ground state properties as a function of magnetic field H and the Kondo exchange coupling. While an isolated impurity of spin S>1/2 has a magnetic ground state of effective spin (S−12), a finite concentration introduces a heavy impurity band and yields a singlet ground state with antiferromagnetically correlated impurities. A field H first polarizes the narrow impurity band. The impurities have mixed valent properties induced in part by correlations in the host. Some aspects of the model are related to heavy fermion alloys.


Lube ability of inactive oil was examined under friction of steel specimens with and without some carbon diamond-like coatings. It was shown that the inactive oil pure liquid paraffin provides better antifriction properties under friction tests of specimens coated by highly ordered monocrystalline carbon coating as compared with uncoated steel and amorphous coatings deposited on steel and titanium sub-strates. The obtained results can be explained by the difference in the level of molecular orientation in lube boundary layer depending on the level of solid surface i.e. carbon coating ordering.


A Modified Quick Convergent Inflow Algorithm (MQCIA) for Solving Linear Programming problems, based on variance of predicted response, is presented. The method adds a point of maximum variance to an initial design thus leading to a maximizer of the response function in a maximization problem. Similarly, a point of minimum variance is added to an initial design thus leading to a minimizer of the response function in a minimization problem. Effectiveness of the method has been demonstrated and the results show that by improving an existing experimental design, the optimizer of the response function is approached. Analytical justification for the MQCIA has also been established.


Significance We have developed a bioinformatics tool that allows us to compare the sequences of all protein-coding genes of 36 sequenced mouse inbred strains with the reference mouse strain C57BL/6J. We also provide an estimate of the effect on protein function of each deviant protein sequence and have built a searchable database of all these sequences, giving researchers the opportunity to search for abnormal alleles of any protein coding gene across these strains. The database makes the enormous richness of variant alleles present in these 36 inbred strains visible, accessible, and useful to the whole mouse research community. Mouse inbred strains remain essential in science. We have analyzed the publicly available genome sequences of 36 popular inbred strains and provide lists for each strain of protein-coding genes that acquired sequence variations that cause premature STOP codons, loss of STOP codons and single nucleotide polymorphisms, and short in-frame insertions and deletions. Our data give an overview of predicted defective proteins, including predicted impact scores, of all these strains compared with the reference mouse genome of C57BL/6J. These data can also be retrieved via a searchable website (mousepost.be) and allow a global, better interpretation of genetic background effects and a source of naturally defective alleles in these 36 sequenced classical and high-priority mouse inbred strains.


Home automation offers a good solution to help conserve our natural resources in a time when we are all becoming more environmentally conscious. Home automation systems can reduce power consumption and when they are not in use automatically turn off lights and appliances. With home automation, many repetitive tasks can be performed automatically or with fewer steps. For example, each time the person gets out of his computer desk, for instance, the fan and the lights need to be turned off and switched on when he comes back to the computer desk. This is a repetitive task, and failure to do so leads to a waste of energy. This paper proposes a security/energy saving system based on face recognition to monitor the fan and lights depending on the presence or absence of the authenticated user. Initially, the authenticated faces/users LBPH (Local Binary Pattern Histogram) features were extracted and modelled using SVM to construct the face profile of all authenticated users. The webcam catches the user's picture before the PC and the Haar-cascade classifier, a profound learning object identification technique is used to identify face objects from the background. The facial recognition techniques were implemented with python and linked to the cloud environment of Ada-Fruit in order to enable or disable the light and fan on the desk. The relay status is transmitted from Ada Fruit Cloud to Arduino Esp8266 using the MQTT Protocol. If the unidentified user in the webcam is detected by this device, the information in the cloud will be set to ' off ' status, allowing light and fan to be switched off. Although Passive Infrared Sensor (PIR) is widely used in home automation systems, PIR sensors detect heat traces in a room, so they are not very sensitive when the room itself is hot. Therefore, in some countries such as INDIA, PIR sensors are unable to detect human beings in the summer. This system is an alternative to commonly used PIR sensors in the home automation process.


Using non-participant structured observation of classroom teaching as a method of collecting data was experienced; during a one hour session, the researcher noted who was speaking at 5-minute intervals.  Preparation of a chart for 7 expected students became unwieldly when some 20 students attended, which was not anticipated.  It soon became obvious that 5-minute intervals were too long, as many students spoke up but not at the points where speaking was recorded, so the final chart was unrepresentative of the classroom behaviour being observed.  In addition, the researcher became involved in answering a question themselves, something that should not occur when using a non-participant approach.


The insulating granular film of Co±Al±O consists of nano-scaled magnetic granules of cobalt embedded in amorphous alumina. This kind of system shows a large tunnel-type giant magnetoresistance (TMR) effect at room temperature when its composition and microstructure are appropriate [1]. Similar to the other fine magnetic particle systems, the grains in this film may correlate each other. However, this correlation can not be detected by the usual magnetization measurement owing to the fact that the film is superparamagnetic at room temperature. Bearing in mind that the TMR ratio is directly related to the angle between magnetic moments of neighboring grains, we have investigated the magnetic interaction in this system by measuring the TMR ratio as a function of a low external magnetic field. The Co54Al19O27 film was prepared by radio frequency reactive sputtering. Its composition was analyzed via Rutherford Backscattering Spectrometry (RBS). The TMR ratio (R(0) ± R(H))/R(H) reaches 7% under a 1.5 T field. It shows no hysteresis in magnetization at room temperature, which is fitted reasonably well by the Langevin function. The TMR was measured under low and high fields at room temperature by the conventional fore-probe method. Taking into consideration the spin-dependent tunneling between neighboring grains, the conductance of insulating granular films was deduced [2]


Fecal digestible energy (DE) and ileal digestible crude protein (CP) and amino acid (AA) contents in sorghum, pear millet, high-oil corn, high-oil-high-protein corn, regular corn I and II were determined in growing pigs fitted with ileal "T "cannulas. The cereal grain samples were grown in Canada and supplemented with vitamins and minerals to produce six experimental diets. Six pigs, with an average initial body weight of 17 kg, were fed the diets during six subsequent experimental periods according to a Latin square design. Pigs were fed twice daily at 2.6 times maintenance energy requirements. After a 7-d adjustment period, feces were collected for 3 d, followed by a 48-h collection of ileal digesta. Apparent and standardized ileal AA digestibilities were calculated. The high-oil corn and high-oil-high-protein corn had the highest (P < 0.05) DE content [4029, 4048 kcal kg-1 dry matter (DM), respectively]. The sorghum had a higher (P < 0.05) DE content (3941 kcal kg-1 DM) than pear millet (3603 kcal kg-1...