Institute for Community Empowerment (Lembaga Pemberdayan Masyarakat – LPM) has been established in Bontang City area since 2001 and strengthened by Regional Regulation No. 12 of 2003 on the Institute for Community Empowerment and RT in Bontang City area. This paper aimed to describe the presence of LPM in bringing progress to the Bontang city development. There are four sectors that receive equal attention from the LPM, which includes the religious, infrastructure development, human resources and economics. To develop those four sectors LPM has several functions, consist of: fertilizing sense of unity and cohesion function, coordination plan and perform function, coordination and plan of social institutions function, and utilization of public funds for rural development function. The first three functions had been implemented well, while the last function was implemented quite well. However there were concerns about the process of development planning where participatory approach was not all active. Having this results, it can be conclude that the presence of LPM has positively influence the development in Bontang City. Keywords : Community Empowerment Institution.


In the relatively young history of computers, their capability has grown at an exponential rate – both in hardware (see Moore's Law), and in software. Naturally, along with the increased potential came the greater magnitude of complexity. Where mainframes used to run isolated instructions from single programs, today's conditions require multiple interactions at every level – each CPU multitasks dozens of processes, servers manage their load between multiple CPUs, application tiers take advantage of server farms to manage load, service providers require multiple tiers for efficient services. An industrial-strength service architecture pushes the limits of descriptive reliability models, as the number of nodes and connections in dependency graphs of the service components grows rapidly. Without a doubt, the inherent complexity of service providers, whether it is a brokerage firm, an online retailer, a search engine or a portal, is significant. But on the other hand, the availability of the Internet and global access require these providers to be available 24 hours a day, seven days a week. Reliability being a major concern, much of the marketing literature for service components is filled with terms like "five nines", signifying 99.999% availability – but in real life, we typically find that reliability is much less – anyone with a computer has grown accustomed to encountering various faults, in a manner not applied to older technologies, like land-line phone service or automobiles.


Over the past several decades, the U.S. has seen marked declines in smoking, due in part to increased education and cessation efforts.


The overall objective of the Integrated Demonstration Project for the Remediation of Organics at Nonarid Sites at the Savannah River Site (SRS) is to evaluate innovative remediation, characterization, and monitoring systems to facilitate restoration of contaminated sites. The first phase of the demonstration focused on the application and development of in situ air stripping technologies to remediate sediments and groundwater contaminated with volatile organic compounds (VOCs). The second phase focused on the enhancement of the in situ air stripping process by adding selected nutrients to stimulate naturally occurring microorganisms that degrade VOCs. The purpose of the third phase was to evaluate the use of heating technologies [radio frequency (rf) and ohmic heating] to enhance the removal of contamination from clay layers where mass transfer is limited. The objective of this report is to document pretest and post-test data collected in support of the rf heating demonstration. The following data are discussed in this report: (1) a general description of the site including piezometers and sensors installed to monitor the remedial process; (2) stratigraphy, lithology, and a detailed geologic cross section of the study site; (3) tabulations of pretest and post-test moisture and VOC content of the sediments; (4) sampling andmore » analysis procedures for sediment samples; (5) microbial abundance and diversity; (6) three-dimensional images of pretest and post-test contaminant distribution; (7) volumetric calculations.« less


Large-scale data processing prompts a number of important challenges, including guaranteeing that collected or published data is not misused, preventing disclosure of sensitive information, and deploying privacy protection frameworks that support usable and scalable services. In this dissertation, we study and build systems geared for privacy-friendly data processing, enabling computational scenarios and applications where potentially sensitive data can be used to extract useful knowledge, and which would otherwise be impossible without such strong privacy guarantees. For instance, we show how to privately and efficiently aggregate data from many sources and large streams, and how to use the aggregates to extract useful statistics and train simple machine learning models. We also present a novel technique for privately releasing generative machine learning models and entire high-dimensional datasets produced by these models. Finally, we demonstrate that the data used by participants in training generative and collaborative learning models may be vulnerable to inference attacks and discuss possible mitigation strategies.


Recommended Citation Poitras, Marie-Eve; Godbout, Isabelle; T Vaillancourt, Vanessa; Débarges, Béatrice; Poirier, Annie; Prévost, Karina; and Spence, Claude (2020) "Step-by-step Strategies for an Integrated Patient-Oriented Research: Lessons Learned from a Multicentered Study," Science of Nursing and Health Practices Science infirmière et pratiques en santé: Vol. 3 : Iss. 2 , Article 3. Available at: https://doi.org/10.31770/2561-7516.1068


Abstract Oxidation of ferritic surfaces prior to gaseous nitriding has been reported to lead to improved compound layer thickness uniformity and enhanced nitriding kinetics. The present work considers the nucleation and growth of a model compound layer on pure iron and, using previous experimental and theoretical results reported in the literature, puts forward two hypotheses to explain the effects of preoxidation on compound layer formation. It is proposed that the nucleation of iron nitrides is enhanced by the presence of an iron oxide layer, and that the growth of an iron nitride layer proceeds faster after preoxidation owing to a higher nitrogen content in the part of the compound layer closest to the surface.


This paper presented the latest advances in the application of biosensors monitoring for BOD?N?P?pathogens?pesticides and heavy metals in the aquiculture environment, and the problems with their applications in monitoring mariculture and reasons for the problems. Meanwhile, the novel technologies of genetically engineered microorganism, of molecular imprinting polymer and of real time multi analysis needed to improve the performance and to extend the application of biosensors for sea fishery, and to offer a prospect of biosensors to be combined with computer to allow online monitoring and control were demonstrated.


This paper introduces the Auto Terrain Generation System (ATGS), which is based on an Interactive Genetic Algorithm (IGA) that enables non-specialist users to rapidly generate terrains. The motivation for using an IGA is discussed, existing terrain generation techniques are described and a new approach, based on a fractal terrain engine, is outlined. Graphics engines allow terrains to be specified with over 800 floating point parameters, which can overwhelm non-specialist users. These parameters also create a vast search space for auto-terrain generation systems that can complicate procedural techniques. ATGS addresses these issues via interaction with the user, which is implemented in ATGS by a web based user interface that allows users to rapidly indicate terrain preferences. These user preferences are used by a genetic algorithm to explore a multi-dimensional parameter space that satisfies the user's intuition and aesthetics. Proof of concept experiments are outlined, results are presented and future research work is projected.


The paper presents the results of mathematical modeling of the subsea permafrost dynamics and distribution on the East Arctic shelf. In this study the geographic distribution of the geothermal flow values was taken into account. Estimates of the permafrost thickness on the Laptev and the East Siberian seas shelf have been obtained. The depth of occurrence of the lower boundary of the frozen layer on the shelf was about 50-700 m. The position of the submarine permafrost upper boundary in the bottom sediments of the seas of the East Arctic substantially depends on the depth of the sea and the content of salts. It was found that the upper boundary of frozen rocks is located at a depth of 15-30 m below the seabed, depending on the shelf region. The increased heat flux leads to a significant decrease in the thickness of the submarine permafrost on the outer shelf and in the rift areas.


Healthcare systems around the world are, at long last, becoming digital systems—probably the last economic sector to undergo this transformation. In the United States, approximately 50% of office practices now have at least basic electronic health record systems; and the same is true for over 80% of hospitals. Some nations, most notably in Northern Europe, have had almost completely digital health systems for decade. Other nations vary in their progress, but the trending around the world is uniform and positive.


We are in the moment of crisis in the global transformation, which is analogous to Karl Polanyi"s Great Transformation of the 20th century. The neo-liberalism that drove the disembedded phase of the transformation, known as "globalisation", sought to create a global market society in which principles of commodification were extended in every feasible sphere of life, including the educational system, family life, occupational development and social policy.[1] It reached its moment of nemesis in the financial crash of 2007-2008, since when it has been staggering, opening up some ugly political scenarios.


2-Cyclopentylidenecyclopentanol (I) was hydrogenated over Raney Ni to produce a mixture of 95% of trans- and 5% of cis-2-cyclopentylcyclopentanol (III). However, over a Pd catalyst I gave a mixture of 2-cyclopentylcyclopentanone (IV), cyclopentylcyclopentane (V) and trans-and cis-III. In the hydrogenation of I over PtO2, trans-III was a predominant product (93%) in ethanol, whereas in acetic acid a mixture of 2 parts of trans- and 1 part of cis-III was obtained, and in acetic acid with one drop of hydrochloric acid, the ratio of trans and cis was one to two. A large amount of V was also obtained in cases of both acetic acid. The hydrogenation of 2-benzylidene-1-tetralol (II) resulted in 2-benzyl-1-tetralols (VI), the yields of trans- and cis-VI being as follows: over Raney Ni, 78% and 19%; over Pd, 33% and 63%; and over PtO2 in ethanol, 58% and 34%, respectively. From these results, it was found that, in the cases of Raney Ni and PtO2 in ethanol, the directive effect of the hydroxyl group is very efficien...


Thin film device with a located in a first plane over a substrate resistive film the resistance essentially determines the function of the thin film component and contained in an immediately adjacent to the first second plane thin covering layer in the manufacturing and operating conditions of the thin film device intrusion excludes from functioning changing elements in the thin resistive layer from the environment and from the covering layer itself, said specific conductivity of the covering layer is anisotropic and the thin resistive layer in both the functional areas, in which the action of a physical quantity will the conductivity of the thin resistive layer as well as changes in the contact areas where the thin resistive layer of a third located in a plane immediately adjacent to the second level contact layer by the protective layer toward is accruing by electrical currents or flow out to her, covered.


A prefabricated laminated sandwich equivalent shear continuous cast steel wall structure, a prefabricated outer leaf overlap shear, insulation, laminated preform the intermediate plate shear wall, steel lattice, superimposed prefabricated shear vane walls connected to form a force, the prefabricated intermediate plate superimposed shear plate and the inner leaf, at both ends is shorter than the pre-folded outer vane shear and insulation, and reinforcement projects, construction and installation when the upper shear laminated preform the intermediate plate, the intermediate plate downwardly projecting vanes and the lower reinforcement preforms are superimposed shear walls, the inner blade steel plate projecting upward is fixedly connected, then the middle and inner leaves pouring concrete between the plates to form a shear wall structural system comprising situ and is equivalent to the insulation layer. Thermal insulation of the present invention, the seismic capability, high structural strength and shear resistance, can not be used to break shear sandwich laminated technical problems rise buildings, industrial production.


Huntington's disease (HD) is a progressive neurodegenerative disorder inherited in an autosomal dominant fashion, characterized by motor abnormalities, cognitive impairment, and psychiatric disturbances (Harper, 1991). Huntington's disease is caused by an increased CAG repeat number in a gene coding for a protein called huntingtin (HDCRG, 1993; DiFiglia et al., 1995). The trinucleotide CAG codes for the amino acid glutamine and the expanded CAG repeat is translated into an unbroken glutamine stretch (polyglutamine protein). The development of the disease phenotype is related to the aggregation of the HD gene products in the cytoplasm (Walling et al., 1998). The HD gene has been found to be expressed in the brain and in various other tissues, but the normal cellular function is still unknown (Wanker et al., 1997). Huntingtin has been demonstrated to interact with several proteins, among them GAPDH, calmodulin, huntingtin interacting protein (HIP1) (Wanker et al., 1997) and huntingtin associated protein (HAP1) (Li et al., 1995). Both HIP1 and HAP1 interact with the polyglutamine tract in the mutated huntingtin, but only HAP1 binds in a CAG-dependent manner and is specific to the CNS (Kalchman et al., 1997, Li et al., 1996). Animal models, especially the rat and mouse, have been used for further elucidation of the molecular mechanisms underlying Huntington's disease development and progression (Page et al., 1998). The huntington gene has been mapped to human chromosome 4p16.3 (MacDonald et al., 1992) and mouse chromosome 5 (Nasir et al., 1994), the HAP1 gene to human chromosome 17q21.2→q21.3 (Nasir et al., 1999; 2000) and mouse chromosome 11 (Nasir et al., 1999) and the HIP 1 gene to human chromosome 7q11.23 (Wedemeyer et al., 1997) and mouse chromosome 5 (Himmelbauer et al., 1998).


history with an account of water transport in the French regime, and then discusses in turn the activities of the fur traders from 1763 to 18~1, the early development of waterways for sail and steam transportation, the evolution of roads in the Provinces, and the beginnings of railroad construction. Most of the remaining threefifths of the volume is devoted to an account of the location, construction, and financing of the Canadian Pacific Railway and other lines to the Pacific, and


Insulin secretion and peripheral insulin sensitivity were studied in 19 grossly obese girls and 17 age-matched non-obese girls by means of the intravenous glucose tolerance test (IVGTT) and the simulated early insulin response test (SERT), respectively. The SERT measures the fall in fasting blood glucose after a short infusion of insulin, performed so as to simulate the early phase of insulin release to an acute stimulus (ERex). At the IVGTT, the obese girls showed significantly increased early insulin response (ERend) in comparison with the non-obese girls. In the SERT, the rise in plasma insulin caused a much smaller decrease in blood glucose in the obese girls than in the reference girls. The relationship between insulin sensitivity and insulin secretion of each subject was evaluated from the plot of the ERex/ERend ratio vs. blood glucose decrement. This showed tKat the hyperinsulinemia of the obese girls frequently did not match the degree of peripheral resistance. The results support the concept that hyper-function of the beta-cells is an effect secondary to the insulin resistance of peripheral tissues.


Objective: To investigate the clinical diagnosis and treatment of upper digestive tract perforation. Methods: Select 32 cases of upper digestive tract perforation,among them 31 cases employ emergency operation treatment,29 cases employ simple repair,2 cases employ a majority of gastrectomy,1 case employ expectant treatment. Results: Thirty-one cases cured,and 1 case died. Conclusions:Selecting reasonable operation type,striving early operation,strengthening perioperative management,and active preventing and treating complications and basic disease for the patients with upper digestive tract perforation according to their pollution level of abdominal cavity,lesion site,nature of lesion,and patient's age and basic diseases can improve curative effects.


In response to the existing flight forecasting system and the loss of passengers caused by flight delays, a new indicator was proposed: EFAT. After using wavelet analysis method to extract outliers in data, this paper predicts flight arrival time based on BP neural network model optimized by Levenberg-Marquardt algorithm. Referring to flight data from Airsavvi official website, the RMSE of the model's prediction results and actual data is about 39 minutes, of which 97.28% of the prediction errors are within 26 minutes.


At the fifth meeting of the Jules Gonin Club held in Munich in August 1966, consideration was given to the twin topics of current techniques in the management of intraocular tumors and methods to avoid excessive surgery in the repair of retinal detachment. This volume contains in succinct form the various papers delivered at that meeting in English, German, or French, with brief resumes in English following each paper. In the first portion of the book, interest in current methods of treatment of malignant tumors of the posterior segment is stimulated by enthusiastic reports regarding therapy with light coagulation or radioactive discs. Francois reported that 26 patients with choroidal melanomas in the early stages were cured of the tumor by light coagulation, while Stallard stated that 83 of 107 patients showed postirradiation recession of the tumor following application of a radioactive cobalt disc. The success rate, as one would expect,


The objective of the present study is to examine the very low frequency periodic components of the fetal heart rate during labor in relation to the oxygen saturation of the fetal arterial blood. In order to analyze and quantify the periodic dynamics of the fetal heart rate variability in the very low frequency (VLF) range, we apply the matching pursuits (MP) method. This method has the ability to identify multiple periodicities in a highly nonstationary signal and we focus on the sinusoidal-like activities between 0.01 and 0.04 Hz. We demonstrate that the VLF activity of the fetal heart rate is increased when the oxygen saturation of the fetal arterial blood is diminished below the threshold value of 30% and the umbilical artery pH is lower than 7.15.


In order to find less toxic antiviral agents from Basidiomycetes, EA, the water soluble substance, was prepared from the carpophores of Elfvingia applanata (Pers.) Karst. Antiviral activity of EA against vesicular stomatitis virus [New Jersey serotype, VSV(NJ)] was examined in Vero cells using plaque reduction assay in vitro. And the combined antiviral effects of EA with interferon (IFN) alpha and gamma were examined on the multiplication of VSV(NJ). EA caused a concentration-dependent reduction in the plaque formation of VSV(NJ) with 50% effective concentration of 2.10 mg/ml. The results of combination assay were evaluated by the combination index (CI) that was analysed by the multiple drug effect analysis. The combination of EA with IFN alpha showed more potent effect with CI values of for 50%, 70% and 90% effective levels than that with INF gamma with CI values of .


To provide information for understanding nutrient cycling and energy flow in fluvial ecosystems,this paper studied the litter decomposition and elements release dynamics in river water of Dongfeng River in Zhengzhou city,Henan province,using string mesh bag technique. The trail was taken on for 39 days. The results showed that the litter mass had a continuous decreasing pattern and lost 11.6% of the total mass in decomposing process. The trend of dry mass 1oss followed the negative exponential equation. The decomposed time of 95% litter were 8.21 years. The biological and non-biological factors had significant influence on the nitrogen and phosphorus release of the litter. In the first 9 days,nitrogen in the litter lost rapidly,then gradually rise a little,and then,in the last 10 days,lost rapidly again. Meanwhile,the phosphorus in litter showed a fluctuating losing trend during decomposition period:decreased and then increased at the first and medium stage,and decreased again at the late stage. According to the nitrogen accumulation index (NAI) and phosphorus accumulation index (PAI),the nitrogen and phosphorus in litter was mainly released,and had an alternant change characteristics of release-accumulation-release course.


Diabetic peripheral neuropathy (DPN) is a disabling long-term microvascular complication of diabetes mellitus. It is estimated that 40% to 50% of people with diabetes will have detectable DPN within 10 years of diagnosis.1 Patients with diabetes with peripheral neuropathy are at an increased risk for foot ulceration that, if untreated, could result in amputation and neuropathic pain that can cause significant morbidity. Chronic sensorimotor DPN is the most commonly seen neuropathy in diabetes. Patients may experience symptoms such as burning pain, electrical or stabbing sensations, paresthesia, hyperesthesia and deep aching pain.2

The Canadian Diabetes Association Clinical Practice Guidelines (CDA CPG) 2013 recommends that people with type 2 diabetes should be screened for DPN at diagnosis and then annually thereafter.1 Patients with type 1 diabetes should be screened 5 years after the postpubertal duration of diabetes and then annually thereafter.1 Screening for DPN can be conducted using a 10 g Semmes-Weinstein monofilament or a 128-Hz tuning fork.1

The early detection and control of DPN are crucial because up to 50% of patients may be asymptomatic.2 This puts patients at risk for developing unnoticed injuries to their feet, leading to foot ulcers.2 A large number of patients with DPN are not identified, and they are likely to miss early intervention to prevent the progression of DPN.3

NC-stat DPNCheck, manufactured by NeuroMetrix Inc. (Waltham, MA), is a point-of-care device that measures sural nerve conduction velocity (CV) and sensory nerve action potential (SNAP) amplitude. Sensory nerve action potential amplitude and CV have been shown to be sensitive indicators of nerve degeneration in patients with diabetes and have been used to detect DPN.4 Diabetic peripheral neuropathy is associated with low SNAP amplitude and CV.4 This instrument has been shown to have a sensitivity of 92% and a specificity of 82% when compared to traditional nerve conduction studies in patients with DPN, with reproducible results.5,6

This article reports the use of the NC-stat DPNCheck testing device in the community pharmacy setting as an assessment tool for pharmacists when educating patients regarding DPN and glycemic control.


The experimental study on seismic performance of prestressed steel reinforced concrete frame specimen and non-prestressed steel reinforced concrete frame specimen has been carried out.Experimental results indicated that the prestresssd bars used in steel reinforced concrete beams could effectively control the crack widths,and upgrade the serviceability performance of the prestressed steel reinforced concrete frame specimen.The prestressed bars used in beam did not change the good seismic performance of steel reinforced concrete frame,while its hysteretic curves was plump.Also it was confirmed that prestressed steel reinforced concrete frame specimen had good seismic resistance capability and could make full use of the advantages of steel,concrete and prestressed bars.Based on the experimental results,three linear recovery models were proposed,and the hysteretic analysis of prestressed steel reinforced concrete frame specimen and non-prestressed steel reinforced concrete frame specimen were carried out.Analysis results showed good agreement with test results.


Significance An understanding of the mechanisms by which viruses evade host immunity is essential to the development of antiviral drugs and viral detection strategies. Ubiquitin and ubiquitin-like modifications are crucial in cellular innate immune and infection responses and are often suppressed by viral proteins. We here identify a previously unknown mechanism of viral evasion. A viral protease, Lbpro, removes ubiquitin and the ubiquitin-like protein ISG15 incompletely from proteins. While this strategy efficiently and irreversibly shuts down these modification systems, it enables repurposing of tools and technologies developed for ubiquitin research in virus detection. Specifically, we show that foot-and-mouth disease virus infection can be detected using an anti-GlyGly antibody developed for ubiquitin mass spectrometry research. In response to viral infection, cells mount a potent inflammatory response that relies on ISG15 and ubiquitin posttranslational modifications. Many viruses use deubiquitinases and deISGylases that reverse these modifications and antagonize host signaling processes. We here reveal that the leader protease, Lbpro, from foot-and-mouth disease virus (FMDV) targets ISG15 and to a lesser extent, ubiquitin in an unprecedented manner. Unlike canonical deISGylases that hydrolyze the isopeptide linkage after the C-terminal GlyGly motif, Lbpro cleaves the peptide bond preceding the GlyGly motif. Consequently, the GlyGly dipeptide remains attached to the substrate Lys, and cleaved ISG15 is rendered incompetent for reconjugation. A crystal structure of Lbpro bound to an engineered ISG15 suicide probe revealed the molecular basis for ISG15 proteolysis. Importantly, anti-GlyGly antibodies, developed for ubiquitin proteomics, are able to detect Lbpro cleavage products during viral infection. This opens avenues for infection detection of FMDV based on an immutable, host-derived epitope.


Introduction: Body diffusion weighted image (DWI) has been proposed recently as a sensitive tumour detection method. Apparent Diffusion Constant (ADC) is promising as an index for early cancer therapy response. One of the major issues with abdominal DWI is signal loss that notably appears in the left lobe of the liver due to cardiac pulsation. Another major issue is image blur caused by respiratory motion. On conventional MR imaging, triggering techniques (cardiac or respiratory) are widely used to eliminate motion effects. However, due to severe scan time prolongation, only respiratory triggering (RT) DWI is performed in clinical studies. A recent study [1] shows that cardiac motion affects not only the left lobe but also the right lobe, which may cause artificially elevated value and poor reproducibility of the measured ADC. The purpose of this study is to demonstrate a method that compensates both respiratory and cardiac motion effects with clinically feasible scan time.


A conveniently amplified DNA AND logic gate platform was designed for the highly sensitive detection of low-abundance DNA fragment inputs based on strand displacement reaction and rolling circle amplification strategy. Compared with others, this system can detect miRNAs in biological samples. The success of this strategy demonstrates the potential of DNA logic gates in disease diagnosis.


This study examines the effects of a scale-reduced play environment on temporal aspects of play behavior. Specifically, it examines the amount of time required to enter complex forms of play, the length of play segments, and the percentage of total play time spent in complex play under normal environmental conditions (full-size, control) and under scale-reduced environmental conditions (experimental). Eleven subjects (mean age of 4 years 2 months) were observed during unstructured play activity with playdough in a small-n, A-B-A-B design. Subjects served as their own controls and were self-motivated relative to the activity. The play structure (scale-reduced environment) consisted of a screened wooden frame 7' (L) x 5' (W) x 5' (H) over a vinyl floor. Results indicate subjects enter complex forms of play more quickly, engage in play segments of longer duration and tend to spend a slightly greater percentage of their overall play time in complex play under experimental conditions, as hypothesized. This stu...


Norton Sound.--Water depth range is 10 to 20 meters; the seafloor is subhorizontal and mostly smooth, but shallow ice gouges and pock marks are common in some areas. Shallow soils are chiefly dense silts at depth. Strata are typically flat lying. Silts may present unusual foundation problems because they can be have as either a granular or cohesive soil depending on loading rate. Significant "geo hazards" are sea ice and scouring by both currents and sea ice. Navarin Basin.--Water depth range is 130 to 400 meters; the seafloor is typically smooth and subhorizontal. Shallow soils are inferred to be chiefly underformed clayey strata with some interbedded sands and silts. Foundation conditions may be grossly similar to conditions off much of western Louisiana and Texas. Significant "geohazards" may be oceanographic conditions, including sea ice. St. George Basin.--Water depth range is 100 to 170 meters; the seafloor is smooth and subhorizontal. Shallow soils are chiefly clays with


Apollo Tyres, headquartered in India, has gone through multiple sets of difficult times during its short history, including near-bankruptcy. Onkar S. Kanwar, chairman of Apollo Tyres, offers key lessons for all companies on how his company dealt with setbacks and challenges to become India's leading automotive tire manufacturer, with operations on three continents.


Chaotic and stochastic characteristics of natural phenomena are fully different. It is the foundation for simulation and prediction of industry accident to distinguish the industry accident system evolvement from its chaotic and stochastic. The characteristics of the industry accident evolvement are analyzed in this paper. The preliminary result shows that the industry accident evolvement has some characteristics of chaotic behavior, and its chaotic characteristics are judged by using phase space reconstruction and Lyapunov exponents.


In the course of follow-up analyses of visual field test,it should take more than two visual field tests that had similar results as baseline test,and some factors should be taken into account,such as accordant testing conditions,reliable indeces,test errors and fluctuation effects,and so on.The indeces of Mean Deviation(MD)and Pattern Standard Deviation(PSD)could reflect the whole change trend of follow-up visual field test,while sensitivity value of every point and their pattern deviations could help to analyse tiny changes of visual field tests.Those statistic softwares provided by automatic perimetry should be used adequately.Through the follow-up analyses of visual field test,glaucoma doctors could adjust therapy schemes in time in order to obtain objective intraocular pressure and stabilize visual field and glaucoma.


Back groundchronic Kidney disease (CKD) is a complex condition, where the decrease in kidney function is accompanied by numerous metabolic changes affecting virtually all organ systems of the human body. It is estimated that 1,00,000 new patients of End Stage Renal Disease (ESRD) enter renal replacement programs annually in India. Aimto determine the Pre and Post levels of serum Ferritin and Ceruloplasmin in Chronic Kidney Disease (CKD) patients on Hemodialysis. Material and MethodsCKD patients who are on maintenance dialysis were studied during the period of 2009-2011. Pre and Post levels of Ferritin and Ceruloplasmin were measured by Latex Enhanced immunotrbidimetry and Terbidometric Immuno assy method. Control group consisted with normal subjects without CKD matching in age and sex with the patients. Statistical analysisdata were analyzed using 't' test for their level of significance. Resultsthe mean Ferritin levels in Pre and Post hemodialysis samples was significantly higher than in the controls. The mean Ceruloplasmin Pre and Post levels in CKD patients showed highly significant increase as compared to control group. Low degree association between serum Ferritin and Ceruloplasmin in CKD patients on Hemodialysis was observed. Conclusionferritin and Ceruloplasmin levels showing a higher status of inflammation and infection. Inflammation implicated as one of the reason of the high burden of atherosclerotic cardiovascular disease and death in CKD patients. Key wordsChronic kidney disease,Ferritin, Ceruloplasmin Introduction CKD is a public health problem with increasing prevalence, with poor outcome and high cost. The major adverse outcomes of CKD include loss of kidney function sometimes leading to kidney failure, complications of decreased kidney function and also development of cardiovascular disease and premature death. According to the first annual report published by the CKD registry of India involving patients, Diabetes and Hypertension were major cause of CKD in India according for 28.5% and 16.2% respectively as in other parts of the world. 1 The prevalence of CKD is raising world wide. The global patient population with an ESRD continued to grow at the rate of 7 % per annum due to demographic transition, increase in disease leading to chronic renal disease and increased availability of diagnostic and therapeutic facilitis. 2 Hemodialysis is the mainstay of Indian Journal of Basic and Applied Medical Research; September 2016: Vol.-5, Issue4, P. 584-587


Aluminum foam metal was produced directly from the foaming method. In this foaming process, the surface tension and the viscosity of molten Al that were measured by the ring method and the rotational method, respectively, and are the two most important factors. The surface tension and the viscosity were investigated at the temperature range of 660-950 °C and the effects of the additional Ca were investigated at the same temperature range. The measured surface tension of the molten Al decreased linearly with the increasing temperature of Ar atmosphere and 1 atm. It follows the function of σ(T)=842-0.204(T-T m )[mNm -1 ]. The viscosity of the molten Al ranged from 3.7 to 4.5[mPa.s] in the temperature range. The effect of additional Ca elements is that the tendency is decreased from the surface tension and increased from the viscosity. The surface tension value was σ 2Ca =530[mNm -1 ] and viscosity value was η 2Ca =14[mPa.s] at the temperature of 700°C, respectively, when adding 2wt% of Ca.


A theoretical treatment is presented for the supralinearity of thermoluminescence glow peaks. The model assumes part of the thermoluminescence trap population as interactive with the thermally disconnected deep traps. These traps produce supralinear growth of the thermoluminescence response. The initial linear part of the response curve is assumed to be produced by the non-interactive part of the thermoluminescence trap population. The treatment enables determination of the relative concentration of deep traps. Resolution of the observed response curve into linear and supralinear parts allows determination of the relative trap populations responsible for producing the linear and supralinear parts of the response. We have also shown the procedure for determining the trap filling constant using the growth profile of the thermoluminescence glow peak of pre-dose sensitized samples. Apart from interpreting the linear and supralinear behaviour of the thermoluminescence response, the treatment provides a quantitative explanation for the pre-dose sensitization effect.


Abstract
 This chapter discusses the clinical aspects of oral tumours in pet animals and highlights the importance of biopsy and histopathology in distinguishing benign from malignant oral masses.


The purpose of this study is to compare innovative technology usage levels of dairy farms, supported and non-supported by The Instrument for Pre-accession Assistance-Rural Development (IPARD) program, by scoring their usage level of 10 innovative technologies in their dairy farms. Another purpose of the study is to determine the factors associated with the innovative technology usage levels of dairy farms. The main material of the study is dairy farms supported and not supported by the IPARD program in Konya. Full count sampling method was used when determining the dairy farms supported by IPARD Program and Neyman allocation sampling method was used when determining the dairy farm non-supported by IPARD program. Research data were collected from 50 dairy farms supported by IPARD program and 100 dairy farms non-supported by IPARD program by administering a questionnaire filled during the face-to-face interviews conducted with each individual respondent. As a result of the study, it was determined that the average gross production values and gross profits of dairy farms supported by IPARD program were 4 times higher than those non-supported by IPARD program. While innovative technology usage level of dairy farms non-supported by IPARD program were entirely low level, 90% of dairy farms supported by IPARD program were high level. From the point of view of dairy farm scale, it was determined that innovative technology usage levels were high (69.84%) in dairy farms that had 51 and more milking cows. As a result of chi-square independence test, statistically significant relationship was found between innovative technology usage level of dairy farm and 12 of 13 factors.


Background: Follicular fluid is in part exudates of serum and is also partially composed of locally produced substances, which are related to the metabolic activity of the follicular cells. The knowledge of the biochemical composition of follicular fluid can provide useful information about the requirements, growth and maturation of oocyte and which may be used as a provisional guide for formulating suitable culture media for in vitro cell culture and maturation in a particular species. Methods: Follicular fluid were aspirated from small follicles ( less than 3 mm; SF), medium follicles (3-5 mm; MF) and large follicles ( greater than 5 mm; LF). Blood samples were also collected for extraction of serum. Follicular fluid and serum samples were analyzed for biochemical constituents. Conclusion: It can be concluded that some biochemical constituents of follicular fluid such as glucose, cholesterol, total protein and globulin were higher in large follicles compared to small follicles. Moreover, serum levels of most of biochemical constituents were higher than their levels in different sizes of follicular fluid. This present investigation of comparative analysis of biochemical constituents between serum and ovarian follicles in Ganjam goat of Odisha will provide clues to researchers who work on reproductive physiology in different breeds of goat.


Psychiatric home care is gaining recognition and acceptance in the home care industry, but there is still a long way to go before it becomes a service that both providers and payors no longer question. A retrospective look will help determine how smooth the journey into the future will be.


Satellites have the potential to support quantum communication over much longer distances than fibre optics networks and, as a result, there is a large amount of investment globally in quantum communication satellites. The Australian National University Optical Ground Station aims to provide ground services support for quantum communication satellites, and enhance the quantum link performance by the use of Adaptive Optics techniques. Numerical simulations have been carried out to assess the advantage of correcting the atmospheric turbulence on quantum downlinks with Adaptive Optics. Fibre coupling efficiency of the communications light onto a single mode fibre has been chosen as the performance metric. We pay special attention to the focusing optics and optimise them for the Single Mode Fibre coupling. We present the minimum requirements for an AO system to produce a significant improvement on the quantum link using off-the-shelf components. This paper gathers the main outcomes of the end-to-end numerical simulation and describes a potential pathway for future atmospheric corrected quantum communications.


PURPOSE: A drain structure of air-conditioner for a vehicle is provided to prevent damage to a drain port by separately manufacturing a lower case and a drain port. CONSTITUTION: A drain structure of air-conditioner for a vehicle comprises a blower and a case for an air conditioner. According to air intake modes, the blower draws in inner/outer air and controls the volume of air discharged within a vehicle interior. The case for an air conditioner comprises an evaporator cooling air blown from the blower. A draining unit is formed in the lower case. The draining unit is made of separate members and discharges condensed water. The draining unit is a drain port(64) composed of an assembly hole(62) and a connection pipe. The assembly hole is connected to the outside of the lower case.


In this study, the anxiety of classroom teacher candidates regarding the education period and school management in the case that the first job they're appointed to is for multi-grade classroom teaching. The data of this study was obtained from the teacher candidates who were final year students in the Department of Classroom Teaching in the Faculty of Bolu Abant Izzet Baysal University (BAIBU) and took the lesson of "Multi-Grade Class Teaching" in the spring term of the 2017-2018 academic year.  In this study, the forms were applied to 116 teacher candidates and 98 of those who answered the questions in an apprehensive and clear way were took under review. The obtained data were analyzed through content analysis. For the validity and reliability of the data, the opinions of teacher candidates were given as quotations. As a result of the research, in the case that the first assignment of the teacher candidates for their profession is for multi-grade class teaching, it is determined that they will show a high level of anxiety regarding education and training in the case of preparing a lesson plan, have difficulties in effectively managing class time and practicing after 2 hours and weekly theoretical lesson, feel anxiety about school management, and the multi-grade class teaching lesson which is taught theoretically as a 2 hour lesson in a week is not sufficient; therefore it will definitely be beneficial to gain their experiences regarding multi-grade class teaching in their practice schools. The suggestions are made according to the results obtained in the study.


Reviewed in this paper are the achievements made in strategy research from 2006 in Chinese academic libraries serving for local culture construction from the aspects of serving for city and community culture construction,participating in immaterial culture heritage protection,development of characteristic literature and database and public cultural service,serving for local characteristic culture,national culture and rural culture construction.


AbstractBAZAN, R., CORRAL, M., PAGOT, M., RODRIGUEZ, A., COSSAVELLA, A., ORONA, C., DEL OLMO, S., RODRIGUEZ. M.I., LARROSA, N., BONFANTI, E. & BUSSO, F. Remote sensing and numerical modeling for the water quality analysis of the Los Molinos reservoir in Cordoba, Argentina. Hydraulic engineering in Mexico (in Spanish). Vol. XX, no. 2, April-June, 2005, pp. 121-135.The province of Cordoba is located in central Argentina, in a semi-arid region where water is a limited natural resource. Los Molinos reservoir represents an essential source of supply for the capital city (with 1.5 million inhabitants). The use of the water body is multiple, including not only the supply of water for human consumption, but also production of electric power, flood control, irrigation, recreation and touristic activities, with some small settlements existing within the boundaries of the lake. Since three decades back, a deterioration of the water quality has been observed, as well as eutrophication signs and periodic algal blooms. Within the scope of an interdisciplinary and interinstitutional research project, a seasonal—and currently monthly—monitoring was started in 1999. In this paper, main sources of phosphorus are identified, as well as their contribution to the total load of the reservoir by means of using the Flux modeling software and indirect calculations. Additionally, hydrodynamic and quality models (Dysrem-Caedym) are also applied, calibrated with field data. Finally, satellite images (Landsat) are used as a tool to develop models of space distribution of quality parameters (chlorophyll-a) in a reflectance function. The combination of remote sensing methods and numerical simulation for the behavior of the system associated to field works will allow to generate new bases for water resources planning and administration, especially on semi-arid regions, such as the Los Molinos reservoir case. Keywords: reservoir, phosphorus, chlorophyll-a, remote sensing, numerical modeling.Direccion institucional de los autores: I.Q. Raquel BazanI.C. Mariano CorralMg. Ing. Mariana PagotDr. Andres RodriguezMg. Ing. Claudia OronaMg. Biol. Maria Ines RodriguezI.Q. Nancy LarrosaUniversidad Nacional de Cordoba, Argentina,Facultad de Ciencias Exactas Fisicas y Naturales,Laboratorio de Hidraulica,Av. Filloy s/n, Ciudad Universitaria,CPA X5016GCA, Argentina,telefono: (+54) 351 433-4446,email@example.com. Fanny BussoLic. Enzo BonfantiMg. Biol. Susana del OlmoAguas Cordobesas, S.A.,Laboratorio Central.Camino La Calera km 13 y 1⁄2, Argentina,email@example.com@email@example.com. Ing. Ana CossavellaDireccion Provincial de Agua y Saneamiento,Humberto Primo 601, CPA X5000FAM, Argentina, telefono: (+54) 351 434-2050 int. email@example.com


Accelerated bridge construction (ABC) is being increasingly used in new bridge construction and repair. For bridge substructure elements, ABC typically requires connections, such as mechanical couplers, between prefabricated elements where moment demands are largest. Grouted sleeves (GSs) offer good construction tolerances and load transfer between precast concrete elements. Therefore, they have gained interest for use in ABC in seismic regions. Large-scale precast column models using GS splices were designed and tested using a shifted plastic hinge (SPH) concept to minimize the damage in the footing and retain the column ductility. The testing matrix considered aspect ratio, moment gradient, and splicing details. Results showed that SPH can be used for flexural and flexural-shear columns; plastic hinging formed above the sleeve region and footing dowels remained elastic to minimize footing damage. Each precast column exhibited good ductility and energy dissipation, and formed slightly shorter SPH length compared with conventional columns.


Duodenal adenocarcinoma being the most common tumor of the small intestine: 33 to 48%, it remains very rare representing only 0.5% of malignant tumors of the digestive tract. Our retrospective study focused on four cases during the period 2017-2022 with an average age of 53.25 years and a sex ratio of 1M/3F. The clinical signs were varied with a predominance of cholestatic jaundice and a deterioration in general condition. The diagnosis was confirmed thanks to the endoscopy and the anatomopathological study of the biopsies carried out in all our patients. All our patients benefited from a surgical treatment, curative or palliative, which consisted of three cephalic pancreaticoduodenectomy and in one case a gastro-jejunal anastomosis. The post-operative follow-up was simple in two patients, one of our patients presented with gastroparesis which progressed well under medical treatment. In addition, we deplore a death which presented a hemoperitoneum related to a hemostasis disorder.


ABSTRACT AT THE START of the second year after initial clinical use of gene replacement therapy, the patient is "doing exceptionally well," says R. Michael Blaese, MD, National Cancer Institute who, with W. French Anderson, MD, National Heart, Lung, and Blood Institute, is one of the principal National Institutes of Health (NIH) clinicians involved in the study (JAMA. 1991; 265:2311-2312).The patient, a 5-year-old girl, has adenosine deaminase (ADA) deficiency, a rare genetic disorder that paralyzes the immune system. On September 14,1990, at the NIH in Bethesda, Md, she received the first of eight infusions of her lymphocytes, cocultivated in the presence of a retroviral vector carrying the missing ADA gene. Some percentage of the lymphocytes pick up the gene and the gene-corrected lymphocytes are reinfused back into the patient.For 2 years before the patient became the first to receive gene replacement treatment, she had been receiving enzyme replacement with


This project consist of making a migration plan for a booking simulator. The booking simulator is in the context of Amadeus, the company I did the intern in. The simulator consists of simulating the user demand (bookings and cancellations of flight tickets) and study how Amadeus systems react in order to maximize the revenue obtained. The migration is focused on the presentation layer of the application: From a Java Swing frontend to a web technology interface. This web technology has to be based on AJAX techniques. A study of AJAX platform has been performed. Several RIA (Rich Internet Application) has been taken in account. The migration plan is detailed and explained in the project. The project has an important weight of Airlines' culture. The project has been developed in the Revenue Management Team.


A brief review is presented of simulation studies and real data experiments which were conducted to assess the impact of satellite observations on numerical weather prediction. These experiments show that while there has been some redundancy between observing systems, satellite data has made significant contributions toward improving global forecasting.


A number of processes involve liquids saturated with significant quantities of gases at elevated pressures, e.g., processes in gas- or CO2-expanded liquids (GXLs, CXLs), particle formation from gas or supercritical antisolvent methods (GAS, SAS, etc.), CO2 capture and sequestration, and enhanced oil recovery (EOR). In order to engineer these systems, the thermodynamic and transport properties are required. This contribution is one of the first reports for the heat transport properties of gas-expanded liquids at elevated pressures. The thermal conductivity, thermal diffusivity, and heat capacity are presented for binary systems of CO2 and the n-alkanes, n-hexane, n-decane, or n-tetradecane, at 25, 40, and 55 °C and pressures up to 106 bar. Equation of state modeling of literature vapor–liquid equilibrium data was used to determine the compositions at the conditions of the experimental heat transport measurements. All measured properties decrease with increasing composition of CO2 (pressure) in a relatively...


A range of 2, 4, 5-triaryl substituted imidazoles have been synthesized in very good yields under solvent-free conditions by grinding 1, 2diketone, aromatic aldehydes and ammonium acetate in the presence of I2, NaH2PO4 and SnCl2.2H20 as catalysts. Optimization of reaction conditions were carried out using different amount of catalysts. 10 mol% catalysts were found to be sufficient catalyze the reaction with high yield. Rate of synthesis of imidazoles and yield of the products were found to be directly proportional to the acidity of Lewis acid catalysts. The short reaction time, green reaction, and simple operation make this protocol practical and economically attractive. Effectiveness of catalysts was found to be of the order of SnCl2.2H2O>NaH2PO4>I2.


Writing multi-threaded code for both correctness and performance is difficult. Often programmers strive for correctness, which may lead to an overly conservative use of synchronization primitives. Even when correct, however, synchronized regions of code (critical sections) may introduce performance variability that causes unexpected software hangs and can be considered a performance bug. These performance bugs are occasional, hard to predict, and may negatively impact the overall user experience. In this paper we present a tool called Iceberg for finding potential software hangs in Java programs. Our focus is on identifying synchronized methods with high variability in their execution time-in particular, if they occasionally run much longer than normal. The key feature of Iceberg is that it records the runtime of every individual execution of a synchronized method, looking for outliers among them, rather than aggregating the runtime the way previous profilers have done. We calibrate our tool using a suite of microbenchmarks with known variability in their critical sections and then tested it with three real world programs. Our results document several cases where our tool finds high variability that could cause real software hangs.


Background Multi-label proteins occur in two or more subcellular locations, which play a vital part in cell development and metabolism. Prediction and analysis of multi-label subcellular localization (SCL) can present new angle with drug target identification and new drug design. However, the prediction of multi-label protein SCL using biological experiments is expensive and labor-intensive. Therefore, predicting large-scale SCL with machine learning methods has turned into a hot study topic in bioinformatics. Methods In this study, a novel multi-label learning means for protein SCL prediction, called DMLDA-LocLIFT, is proposed. Firstly, the dipeptide composition, encoding based on grouped weight, pseudo amino acid composition, gene ontology and pseudo position specific scoring matrix are employed to encode subcellular protein sequences. Then, direct multi-label linear discriminant analysis (DMLDA) is used to reduce the dimension of the fused feature vector. Lastly, the optimal feature vectors are input into the multi-label learning with Label-specIfic FeaTures (LIFT) classifier to predict the location of multi-label proteins. Results The jackknife test showed that the overall actual accuracy on Gram-negative bacteria, Gram-positive bacteria, and plant datasets are 98.60%, 99.60%, and 97.90% respectively, which are obviously better than other state-of-the-art prediction methods. Conclusion The proposed model can effectively predict SCL of multi-label proteins and provide references for experimental identification of SCL. The source codes and data are publicly available at https://github.com/QUST-AIBBDRC/DMLDA-LocLIFT/.


Several influencing factors affect the results of data gathered during magnetic particle inspections, especially underwater. A new technique which makes use of Magfoils eliminates many of these unwanted factors. This technique can be used as the primary system to find discontinuities in ferromagnetic materials or used to confirm defects found by other systems. An online computer is used in conjunction with Magfoils to bring new levels of quality control and analysis into magnetic particle inspections. Non-photographic permanent magnetic images are recorded at the worksite. By reviewing these images it is possible to determine, for example, crack length, width and depth (a new dimension), thus allowing almost instant decisions to be made with regard to repairs. To reduce the bulk of storing the magnetic images, they can be electronically scanned and turned into digitised data files for retention or for transmission to another site for further analysis. This technique is directly applicable to above and below water inspections. When used below water it allows the diver or ROV to use the magnetic particle technique in a more controlled manner than has been possible before.


Figure. A : This lymph node specimen exhibits stellate necrotizing granulomas with central microabscessformation (H&E, original magnification x 100). B: High-po wer magnification shows that the microabscess is surrounded by a peripheral rim ofmacrophages and lympho cytes (H&E, original magnification x 400). C: Rod-shap ed bacteria are seen on silver staining (Warthin-Stan )' silver stain, original magnification x 600).


Slugs are a major pest in arable agriculture that are typically controlled by using pesticide‐impregnated pellets (molluscicides). We received multiple requests from farmers in 2018 for research into the impact of slug pellets on earthworms because they had been told that ferric‐based pellets were 'worm‐friendly'. We measured soil fauna feeding activities within Lumbricus terrestris middens on a replicated field plot experiment comparing the recommended product rates of a metaldehyde (4%) based or ferric phosphate EDDS (3%) based slug pellets. There was a significant decrease in feeding activity in the presence of either type of slug pellet, particularly in the top 25 mm of the soil indicating movement away from the pesticide. This could be explained by the significantly lower abundance (numbers and biomass) of earthworms in the topsoil. Four months after ferric phosphate‐based slug pellet application, there was no significant difference between the control and treated plots in earthworm abundance, indicating the effects were temporary. In the laboratory, individual Lumbricus terrestris earthworms consumed up to 4 slug pellets over 14 days and no significant differences in biomass were measured. A burrowing fitness assay indicated that earthworms exposed to ferric phosphate‐based slug pellets burrowed to a greater depth. This suggests an avoidance behaviour response, which could also explain the field results. A consultation with farmers (n = 68) rated this information service as useful and indicated widespread interest in minimizing the effects of pesticides on non‐target soil fauna.


The exact classical kinetic energy for a system of point masses is obtained. From this the correct form for the quantum‐mechanical Hamiltonian operator is derived. If the assumption of small vibrations is applied to this operator, the familiar approximation of a rigid top plus normal coordinate vibrator is obtained. In order to secure better approximations, in which larger amplitudes of vibration are admitted, a perturbation method is introduced which permits the change of moment of inertia with vibration, the coupling of rotation and vibration, and the centrifugal stretching effects to be taken into account. If the stretching terms alone are neglected, it is possible to reduce the secular equation for the rotational energy levels to the Wang form, except that ``effective moments of inertia'' must be used whose magnitude depends on the vibrational quantum state. The relation of these quantities to the equilibrium moments of inertia or to the instantaneous moments of inertia averaged over the vibrational m...


We present sparse factor graph representations of Reed-Solomon codes based on a fast Fourier transform. Similar " fast " transform factor graph representations are also presented for some extended Reed-Solomon codes. These representations can be used to create encoders, or message-passing decoders that use soft input information. We discuss various simplifications and transformations of the factor graphs that may be useful. Finally, we show that other interesting codes can be represented using sparse fast transform factor graphs. This work may not be copied or reproduced in whole or in part for any commercial purpose. Permission to copy in whole or in part without payment of fee is granted for nonprofit educational and research purposes provided that all such whole or partial copies include the following: a notice that such copying is by permission of Mitsubishi Electric Research Laboratories, Inc.; an acknowledgment of the authors and individual contributions to the work; and all applicable portions of the copyright notice. Copying, reproduction, or republishing for any other purpose shall require a license with payment of fee to Mitsubishi Electric Research Laboratories, Inc. All rights reserved. Abstract. We present sparse factor graph representations of Reed-Solomon codes based on a fast Fourier transform. Similar " fast " transform factor graph representations are also presented for some extended Reed-Solomon codes. These representations can be used to create encoders, or message-passing de-coders that use soft input information. We discuss various simplifications and transformations of the factor graph representations that may be useful. Finally , we show that other interesting codes can be represented using sparse fast transform factor graphs.


Autism is a neurodevelopmental disorder with unclear etiology. Reelin had been proposed to participate in the etiology of autism due to its important role in brain development. The goal of this study was to explore the association and gene–gene interactions of reelin signaling pathway related genes (RELN, VLDLR, LRP8, DAB1, FYN, and CDK5) with autism in Han Chinese population. Genotyping data of the six genes were obtained from a recent genome‐wide association study performed in 430 autistic children who fulfilled the DSM‐IV‐TR criteria for autistic disorder, and 1,074 healthy controls. Single marker case‐control association analysis and haplotype case‐control association analysis were conducted after the data was screened. Multifactor dimensionality reduction (MDR) was applied to further test gene–gene interactions. Neither the single marker nor the haplotype association tests found any significant difference between the autistic group and the control group after permutation test of 1,000 rounds. The 4‐locus MDR model (comprising rs6143734, rs1858782, rs634500, and rs1924267 which belong to RELN and DAB1) was determined to be the model with the highest cross‐validation consistency (CVC) and testing balanced accuracy. The results indicate that an interaction between RELN and DAB1 may increase the risk of autism in the Han Chinese population. Furthermore, it can also be inferred that the involvement of RELN in the etiology of autism would occur through interaction with DAB1. Autism Res 2016, 9: 436–442. © 2015 International Society for Autism Research, Wiley Periodicals, Inc.


Currently, concrete and reinforced concrete structures are an indispensable component of any construction. However, during operation due to the active influence of aggressive components of the atmosphere and the environment, there is a destruction of the protective layer of concrete and corrosion of metal reinforcement.The porous structure of cement stone, which is the basis of concrete, determines the degree of its hydration and, accord-ingly, penetration into it together with moisture aggressive components of the environment (various chlorides, sulfates, carbon dioxide, etc.). The latter leads to a change in the pH of the pore fluid and the development of low destructive processes in the structure of the concrete and metal reinforcement.The detailed analysis of the situation showed that the most favorable conditions, in terms of complete coverage in scien-tific journals, have developed around primary corrosion protection of reinforced concrete structures, which consists in the use of corrosion inhibitors (substances based on various amino compounds, salts of benzoic acids and nitrites of benzoate compo-sitions) at the stage of manufacturing reinforced concrete structures and products from them. The secondary protection of reinforced concrete structures that have been in operation for some time with the use of migrating inhibitor mixtures with good passivation ability and diffusion permeability is less studied, but very relevant.However, to date, there is still no systematic material on the mechanism of their protective action and the effective ratio of molar concentrations of their individual components despite the large number of publications on thedevelopment of migrat-ing corrosion inhibitors as corrosion protection of reinforcing elements of reinforced concrete structures,.In this regard, the purpose of this work is to determine the mechanism for ensuring effective corrosion resistance of metal elements of reinforced concrete structures with the use of migrating corrosion inhibitors.It is shown that the effectiveness of migrating corrosion inhibitors will be determined not only by the nature of its com-ponents, but also by the ratio of concentrations of its passivators of anodic and cathodic reactions, as well as the adsorption component. Monoethanolamine and triethanolamine have been found to be typical surfactants with low surface tension with a satisfactory ability to passivate cathodic reactions, while NaNO2 serves as a passivator for the anodic reaction of steel ioni-zation. The results show that the most effective anticorrosive effect is provided by mixtures with equal ratio of concentrations of adsorption and corrosion inhibiting components (15TEA + 15NaNO2 and 15MEA + 15NaNO2, respectively).Thus, research in the field of corrosion protection of reinforced concrete structures that have been in operation for some time has identified promising ways to develop migratory corrosion inhibitors, mainly related to the creation of synergistic composite compounds that will contain adsorption and passivation components. The effectiveness of inhibitory compositions, which include surfactants based on amine-type compounds, which in combination with sodium nitrites are able to penetrate into the pores of cement stone, reaching the metal reinforcement to inhibit both existing corrosion centers and prevent its occurrence in the future.


In the title compound, [Cu(C6H5N2O2S)2(H2O)2]·2H2O, the Cu atom lies on an inversion centre in a distorted square coordination geometry that consists of two O atoms of two (pyrimidin-2-ylsulfanyl)acetate ligands [Cu—O = 1.953 (2) A] and two O atoms of two water molecules [Cu—O = 1.942 (3) A].


Informatization of ideological and political education in colleges and universities is a new research topic.Based on the concept of informatization of ideological and political education,the paper discusses the specific measures and methods for ideological and political work to enhance effectiveness of ideological and political work in colleges and universities.


This work analyzed different logistics structures under a sustainable perspective. It was developed a discrete event simulation model associated with optimization algorithm to evaluate the best combinations of the model. Besides, the comparison between the simulation optimization and a multicriteria method was performed. The simulation software Ururau, in which a model with optimization algorithm allowed testing different variables, was applied in order to find the best answer to the issue. Results showed that a connection of direct proportionality between variables of transport time, greenhouse gas emissions and lead time can happen. It was also checked that the solution returned by the simulation optimization was similar to the multicriteria method in most of the tests. The ones that differed were due to small mathematical precisions between the methods.


Medicinal plants are a source for a wide variety of natural antioxidants. In the study reported here, we have conducted a comparative study between five medicinal plants having the same geographic origin: the Casablanca region in the West of Morocco and growing in the same natural conditions. The amount of total phenolics and total flavonoids from different parts of plants used in Moroccan popular medicine were evaluated. Furthermore, antioxidant activities for these parts using vitamin C equivalent antioxidant capacity (VCEAC) test were also evaluated. The results show that the antioxidant activities varied greatly among the different plant parts used in this study and some plants are rich in natural antioxidants especially leaves of Mentha pulegium (L.) and of Marrubium vulgare (L.). A positive correlation between total phenolic or flavonoid contents and VCEAC was found with a correlation coefficient of R = 0.939 and R = 0.837, 22 respectively. These findings show that phenolics in these plants provide substantial antioxidant activity.


The problem of future of national cultures and their history is especially actual in the multinational world during an aggravation of interethnic conflicts in many countries of a planet. On an example of process of folding of multinational culture of the Simbirsk-Ulyanovsk region author opens necessity of careful studying of unique centuries old Russian experience on intensive mutual enrichment, mutual influence and to preservation of originality of different ethnocultures.


Answer: Thank you for the opportunity to comment briefly on the recent report published in the journal on research with the HealOzone (KaVo, Biberach, Germany). Ozone cannot do everything and certainly should not be a treatment isolated from our individualised preventive oral health care. To be effective, ozone must be prescribed in sufficient concentration for an adequate time and must be delivered into the lesions.


This paper describes the use of greenways in Washington State. It discusses their potential for increasing economic viability and community involvement. It also describes funding sources and volunteer efforts for beautification and construction projects. Greenways are sometimes referred to as scenic byways.


Using 6-cycle, 7mJ pulses at 1.8µm we exploited limit intensities and drove HHG from 50eV up to the oxygen edge (550eV) with sufficient flux for single shot absorption measurements at the carbon k-edge (280eV).


The agricultural area in Egypt is the largest consumer of water and still requires more water to expand. Any changes in Nile water supply due to climate change would threaten the agricultural water productivities, both physical productivity and economic productivity, and the food security in Egypt. The objective of the current paper is to investigate the impacts of Nile supply reduction on the agricultural water productivities and food security in Egypt using the Agriculture Sector Model in Egypt (ASME). The results showed that the reduction in Nile supply will either increase or decrease the areas of different crops, and generally will decrease the total cropped area. Regarding the food security, all indicators refer to a slight decline in the food security progress in terms of reduction of water availability, self-sufficiency of strategic food crops, and net virtual water import. The reduction in Nile supply will also deteriorate the economic situation, which can be confirmed by the reduction in agricultural productivity, consumer-producer surplus, and number of jobs as well as the increase in net imports' value and water marginal value. The current study recommends implementing adaptation measures to efficiently use the available water resources and to increase the agricultural productivity per unit area.


Composition comprising a kinase inhibitor-3 glycogen synthase for use in increasing a population of progenitor cells or hematopoietic stem cells from adult in a mammalian subject, wherein the inhibitor of glycogen synthase kinase-3 inhibits the expression or activity glycogen synthase cinasa- 3, wherein the inhibitor of glycogen synthase kinase-3 is selected from a GSK3, GSK3 GSK3α or dominant negative polypeptide, a polypeptide comprising an amino acid sequence of a GSK-3 polypeptide, or GSK3α dominant GSK3 negative, a construct RNAi, siRNA or shRNA that binds to and inhibits the expression and / or activity of GSK-3, GSK3α or GSK3, an antisense oligonucleotide that binds to and inhibits the expression of GSK-3, GSK3α or GSK3 , an antibody that binds to and inhibits the expression and / or activity of GSK-3, or GSK3 GSK3α or a ribozyme which binds to and inhibits the expression of GSK-3, or GSK3 GSK3α.


This paper is about professional learning in the context of becoming a teacher. It
presents narrative accounts written by prospective teachers that show how they have
created professional knowledge through inquiry. These narrative excerpts present
the voices of prospective teachers as they deal with their most pressing issues and
concerns, examine prior knowledge in the light of new understandings, and
construct new knowledge through the processes of reflection, dialogue and inquiry.
The details of the narratives are illustrative of the ways in which these prospective
teachers have learned to question the taken-for-granted in their lives, to find patterns
and connections, and to think critically and creatively. They show the people and
the personalities behind the ideas and the issues, and provide glimpses of these
individuals' personal hopes, beliefs, theories, worldviews, passions and
preoccupations. They also provide insights into the processes of creating an
ethically-based professional knowledge in teaching that is unique to each individual.
 These narrative excerpts were written in the context of a year-long teacher
education program in which prospective teachers were enrolled as a cohort in two
consecutive courses in the foundations of Education, Teaching, Students, Schools
and Systems, and Developing a Philosophy in Teaching. These prospective
secondary school teachers specialized in the teaching of two subjects, one of which
they had studied to the level of an advanced degree, and taken a number of
university courses in the other. Many of these individuals had spent a number of
years pursuing other careers before entering the teacher education program, and
consequently brought a range of rich career and life experiences to that setting.


This article focuses on the issue of checking critical observability for labeled Petri nets. Critical observability is a property related to the safety concern of cyber-physical systems. With the aim of checking this property of a net system, it is required to detect whether a set of markings consistent with any observed word of the net system is a subset of a set of critical states representing undesirable operations or a set of noncritical states. In this work, we prove a necessary and sufficient condition to check critical observability when the critical state set is described by an arbitrary subset of reachable markings. Then, the result is extended to the case when a critical state set is modeled by all the reachable markings that satisfy disjunctions of generalized mutual exclusion constraints. The proposed method is derived from the solutions of integer linear programming problems and is applicable to net systems with liveness and boundness. Several case studies show the performance of the presented methodology for discrete-event systems.


The traditional identity authentication approach of username and password has the security risk of password leakage in the transmission process. For the security of password transmission in the blockchain education architecture, an asymmetric encryption algorithm is used to encrypt the transmitted password. Then use an improved random sampling algorithm to randomly extract part of the ciphertext and transmit those selected ciphertexts. The authentication credentials are sampled ciphertext and the location index. At the same time, the authentication factor is generated through the Time-Stamp technology, and mutual authentication is realized based on the Response-Challenge protocol. Through security analysis and experimental analysis, the proposed scheme is proved to be secure.


Wolfram syndrome was first described by physician D J Wolfram and Wagener in 1938. This autosomal recessive syndrome is also referred to as DIDMOAD syndrome which stands for Diabetes Insipidus, Insulin Dependent Diabetes Mellitus, Optic Atrophy and Deafness


Areas covered in this review: The review provides a summary of old and new approaches for GPCR target identification and for the screening of molecules acting on GPCR targets. The new findings in the field are presented as well as an opinion about how these developments may help GPCR drug discovery. Importance in the field: GPCRs have been the most useful family of proteins in terms of targets for drug discovery. The expectations for GPCR target identification and discovery of new drugs acting on 'old' or 'new' GPCR targets are very high. Given the fact that the pace at which new 'GPCR drugs' appear in the market is decreasing and since the new developments in the field are not being translated into drug discovery there is a need to review the field from a critical perspective. Take home message: To overcome the limitation of the old approaches used in GPCR target identification and drugs discovery new approaches are required. In particular successful approaches in GPCR drug discovery should take into account that the real GPCR targets for a given disease are not GPCR monomers but GPCR heteromers. What the reader will gain: The reader will gain an overview of the strategies currently used and their pros and cons. The reader will also understand that new strategies may help in accelerating the access of GPCR into the market, and also notice that successful strategies should take advantage of the new findings in the field of GPCRs.


Immediate extubation in the operating room after congenital heart surgery is practiced with rising frequency at many cardiac institutions to decrease costs and complications. Infants less than one year of age are also increasingly selected for this 'fast track'. However, factors for patient selection, success, or failure of this practice have not been well defined in this population, yet are critical for patient safety.


This article aims to explore some of the fundamental notions that connect the narrative of feminist emancipation to the experience of motherhood. It elucidates any inherent contradictions, appraises their implications for motherhood and assesses their respective salience today for feminist thought. It does so, in particular, by setting motherhood in a wider context where contradictions to feminist theory surface clearly: namely, through dialogues from empirical findings in contemporary motherhood studies and in the context of surrogacy and artificial reproductive technologies (ARTs). Ostensibly, one of the prominent tenets of classic feminism has been its disparaging view of motherhood as being the bastion of women's subordination in a patriarchal society – the corollary being that the emancipation of women could happen only through opposition to or, at best, despite motherhood. The first two sections of the article present classic concepts related to domestic life and motherhood that lambast institutions of male domination, still highly influential in shaping discussions of women's movements around the world. The third section focuses on feminism's controversy over the practice of surrogacy and contends that the epistemological distinction between giving birth and mothering posited by feminism actually legitimizes ARTs' continuing transformation of women's bodies into 'open access flesh'. This is the terrain on which today technology, not patriarchy, is erected. The fourth section surveys a range of vibrant, recent motherhood studies and reclaims the empowering capacity of motherhood at grassroots level, with wider implications. The conclusion raises the issue of 'mothering as empowerment' as a missing piece in the broader landscape of feminist theory, particularly in light of findings that there is a significant concurrence of values and practices characterizing how women with children self-define themselves, as both moral and social agents.


Hypomorphic mutation in one allele of ribosomal protein L24 gene (RPL24) is responsible for the Belly Spot and Tail (Bst) mouse, which suffers from defects of the eye, skeleton, and coat pigmentation. It has been hypothesized that these pathological manifestations result exclusively from faulty protein synthesis. Herein, we challenge this hypothesis and demonstrate that the Bst phenotype is largely caused by aberrant activation of the p53 tumor suppressor during the restricted period of embryonic development. However, in the absence of p53 a large majority of RPL24Bst/+ embryos die, suggesting that p53 also promotes their survival at the expense of malformations. These results also imply that activation of a p53-dependent checkpoint mechanism in response to various RP deficiencies might play a role in the pathogenesis of congenital malformations in humans.


The author indicates the purpose and intent of the initial and periodic inspection and testing required by the IEE Regulations for Electrical Installations (15th Edition)-the 'Wiring Regulations'. The author does not intend primarily to describe in detail the testing methods but rather to consider the logic, philosophy and purpose of the tests and the order in which they are done. The different considerations relating to the initial and the periodic inspection and testing are discussed and the differing relative emphasis on inspection and on testing in the two cases are considered. >


A hybrid discretization scheme for solution of volume integral equation (VIE) by method of moments (MoM) for electromagnetic scattering from dielectric objects is proposed in this article. The Schaubert-Wilton-Glisson and edge (SWG-Edge) hybrid basis functions are used in this discretization scheme. According to the divergence-free condition of electric displacement vector, a kind of edge basis functions defined in elements including boundary faces which separate a dielectric object from the background is derived. As a result, we get a SWG-Edge hybrid basis set. Details for the calculation of the corresponding matrix elements for the edge basis and testing functions are presented. Numerical results show the validity and accuracy of the hybrid discretization scheme. Finally, the proposed method is used for efficient solution of VIE for inhomogeneous dielectric objects with multiboundary. It is shown that for multiboundary problems, the number of unknowns of the hybrid basis is only about 71% of the traditional SWG basis. This means that the memory for solution of VIE by the traditional SWG basis functions can be reduced by half. Therefore, the SWG-edge hybrid basis is much more efficient than the traditional SWG basis for solution of VIE with multiboundary problems.


The world economy as well as public health have been facing a devastating effect caused by the disease termed Coronavirus (COVID-19). A significant step of COVID-19 affected patient's treatment is the faster and accurate detection of the disease which is the motivation of this study. In this paper, the implementation of a deep transfer learning-based framework using a pre-trained network (ResNet-50) for detecting COVID-19 from the chest X-rays was done. Our dataset consists of 2905 chest X-ray images of three categories: COVID-19 affected (219 cases), Viral Pneumonia affected (1345 cases), and Normal Chest X-rays (1341 cases). The implemented neural network demonstrates significant performance in classifying the cases with an overall accuracy of 96%. Most importantly, the model has shown significantly good performance over the current research-based methods in detecting the COVID-19 cases in the test dataset (Precision = 1.00, Recall = 1.00, F1-score = 1.00, and Specificity = 1.00). Therefore, our proposed approach can be adapted as a reliable method for faster and accurate COVID-19 affected case detection.


A simple and efficient two-step hybrid electrochemical–thermal route was developed for the bulk synthesis of CuO nanoparticles using aqueous sodium nitrate electrolyte and Cu electrodes in an undivided cell under galvanostatic mode at room temperature. The influence of electrolyte concentration on the synthesis of CuO nanoparticles was studied at 1.0 A/dm2 current density. Electrochemically generated precursor was calcined for an hour at different levels of temperature in the range 200–900°C. The calcined samples were characterised by XRD, TG-DTA, XPS, SEM/EDAX, TEM, FT-IR and UV–Vis spectral methods. The crystallite sizes were estimated and the thermal behaviour of as-prepared compound was examined. Rietveld refinement of X-ray data shows results matching the monoclinic structure with the space group of C2/c (no. 15). The TEM result revealed that the particle sizes were in the order of 30–50 nm diameter and 120–200 nm length. The blue shift was noticed in UV–Vis absorption spectra. All samples of CuO exhibited randomly oriented hexagonal morphology.


ABSTRACT Objective: To report cases of children and adolescents diagnosed with pseudotumor cerebri associated or not with rheumatic disease. Methods: This was a retrospective study based on medical reports of 29 patients, up to 18 years of age and diagnosed with pseudotumor cerebri, followed up in the Pediatric Rheumatology and Neurology outpatient clinics of a tertiary hospital, until December 2016. Results: Among the 29 patients diagnosed with pseudotumor cerebri, 51.7% were girls and the mean age at the disease onset was 12.3 years. In 18 patients (62%) where an etiology was found, four were associated with a rheumatic disease. The most common symptom was headache (69%) and acetazolamide was the most used medication (69%). Two patients developed blindness and 10 are still being followed up. Conclusion: Although rare, pseudotumor cerebri should be considered in children with headaches, especially in patients with rheumatic disease.


We study the dynamic transmission of monetary policy shocks into firm profitability. By gauging the net effect of consumers' and managers' responses to these shocks, we find an initial negative association between the shocks and firm revenues and expenses. The revenue response is consistent with a consumer substitution effect, while the expense response is consistent with a firm cost of capital effect. In subsequent quarters, the expense effect exceeds the revenue effect, yielding a positive relation between the shocks and profitability. Using cross-sectional tests, we show that substitution (cost of capital) effects are a function of consumers' (firms') financing constraints, firms' industry membership, and the scope of firms' international activities.


In work generalization of results of natural researches of inhabitancy quality in village Pavlovo from Ordimskiy region of Permskiy kray, who constantly living in complex conditions of nature-technogenic pollution and formation of demonstrative base of negative influence of low quality of an inhabitancy on health of the population is lead. The analysis of levels of sharp and chronic influences on the population is carried out, results of clinical-laboratory researches of a health state of adults and children in village Pavlovo are generalized. Calculation of indexes of hazard and levels of cancerogenic risk for health of the population is lead. Priority groups of diseases on which the risk for health exceeds a comprehensible level are certain.


Introduction : Atrial cardiomyopathy (ACM) is a novel subtype of cardiomyopathy characterized by atrial lesions which are associated with significant atrial arrhythmias. Rarely, heritable forms of ACM have been reported, and underlying mechanisms remain unknown. Herein, a 3-generation family affected by ACM with histories of syncope, atrial tachycardia, embolic events and pace maker implantations were enrolled.


relevant to an understanding of this area. And, even within sociolinguistics areas such as anthropology are sadly neglected. One cannot but be struck by the tremendous prominence given in the book to discourse analysis. Four of the chapters (3 ,7 , 9 and 10) are centrally concerned with discourse, while several others deal with the topic in some depth. This is not, of course, surprising, since discourse analysis is one of Stubbs' main areas of expertise and he has made a significant contribution in applying the insights from this field to education. However, in the context of a volume on Educational Linguistics, it might be argued that he presents a highly idiosyncratic and incomplete view of the area. As an introductory text or a balanced overview of the field of educational linguistics, Stubbs' book falls short. As an accessible collection of the work of a perceptive and sensitive linguist who has applied his knowledge to educational settings, I have no hesitation in recommending this volume.


An eight-channel polarimetric temperature sensor for field monitoring of power transformers has been developed and tested. The sensor can work in harsh environment.Test results show the accuracy is better than +/-0.5 °C within 0~200 °C.


The development of space remote sensing technology brings a lot of remote sensing image data. The traditional target detection method is difficult to adapt to the large amount of high-resolution remote sensing image data. It is necessary to find a way to automatically learn the most effective features from the image data, and to fully recover the correlation between the data. Based on the recognition of the typical targets in remote sensing image data, this paper proposes a method of remote sensing target recognition based on deep learning. In this paper, the pre-train method is introduced to improve the simulation of the model. The experiment of the test set proves the validity of the method.


Objective To find the factors to outcome of intracranial injury through study of their association,and establish the formula of probability of death of intracranial injury patients. Subsequently we can get useful information for promoting the cure of intracranial injury.?Methods Besides classification of disease, several factors were screened to fit the logistic model with fatality rate as response variable. Stepwise selection was used.?Results Disease classification, age and admission status of patients entered the model while sex and identity did not. The logistic model is statistically significant.?Conclusion Besides disease classification, age and admission status are associated with outcomes of intracranial injuries.


A small wind power system generally consists of a diode rectifier and a Boost DC/DC converter.Aimed at improving the power generation efficiency and overcoming the system disadvantages,a three-phase PWM rectifier was applied instead of uncontrol rectifier and Boost converter.The work principle and key control method were analyzed and studied,using the TMS320F2812 as control processor for PWM signal generating.Finally,the system model was simulated by Matlab/Simulink,and the results prove the feasibility and the advantages.


The development of microfluidic technologies represents a new strategy to produce and test drug delivery systems. Particularly microfluidics can facilitate the development of new nanoparticles-based systems with controlled physicochemical properties...


Hand evaluation (HE) "FDAI" in Japanese is very important values to evaluate fabric qualities and is nleasured by KES system until now. HE values are obtained by the functions of 16 mechanical properties measured by KES system. Fundamentally these HE values should be evaluated by the feeling of fabric experts hands and be expressed by HE values between 0 to 10 grades, but both method are bothersome. In this paper, we proposed a new method to evaluate HE values by means of neural network of which inputs are the FFT spectrum of drape image. Drape image is obtained by a roundly cut fabric hung on a little round column, where both centers coincide. This method is very simple.


This work presents experiences and practices of gay men and lesbians who opted for alternative religious concepts, self-spirituality or an individual concept of God. Marginalized gay men and lesbians in Serbia are forced to consciously choose between religious traditions to which they belong to by birth and for which their samesex orientations and behaviours are unacceptable, and alternative religious concepts, noninstitutional individual eclectic religious practices and beliefs they create on their own. Search for that particular expression on the spiritual market which would in the best possible way allow harmonization of sexual desires, behaviours and religious identity, the search for forms of religion and spirituality which are compatible with the gay and lesbian sexuality, goes on outside of formal institutions within vary different movements of the New Age spirituality.


We present a detailed and comprehensive picture of the photophysics including device applications within the polyfluorene family of conjugated polymers. First, the photophysics of pristine polyfluorenes in solution and film is outlined, including a discussion of the so-called β-phase, which is characterised by a more planar ground state configuration. Particular attention is also dedicated to the occurence of low energy emission bands, which often deteriorate the initially blue emission of polyfluorenes, especially in electroluminescent devices. Although the origin of these emission features has been the object of a controversial discussion, strong evidence for our current ascription to emissive on-chain fluorenone defects is given also in contrast to previous assignments to aggregates, excimers, or exciplexes. According to the current attribution fluorenone-containing polyfluorenes can be described as a guest host system. Following this picture the photoexcitation dynamics from the fs to the ms regime is outlined. Finally, polymer light emitting diodes (PLEDs) based on polyfluorene-type emitters are discussed, especially related to their degradation mechanisms and possible remedies provided by chemistry to reduce the oxidative degradation of polyfluorene-based PLEDs. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)


The purpose of this study, there are three. (1) Test the effect difference of problem based learning strategies guided inquiry and modified free inquiry on student learning outcomes. (2) Test the effect difference early ability categories of high, medium and low student to student learning outcomes. (3) Test the interaction between early ability category strategy with high, medium and low student to student learning outcomes. This type of research is quantitative with quasi experiment Desai. The study population all students of class VII MTs Ta'mirul Islam Surakarta. The research sample two classes. The sampling technique is cluster random sampling by lottery. Data collection techniques with cognitive testing and documentation methods. Data were analyzed using analysis of variance of two different cell. The results of the study with α = 5%. (1) There are differences in the effect of problem-based learning strategies guided inquiry and modified free inquiry on student learning outcomes. (2) There are differences in the effect of the initial capabilities categories of high, medium and low student to student learning outcomes. (3) There is no interaction between early ability category strategy with high, medium and low student to student learning outcomes.

Keywords: student learning outcomes, initial capabilities, guided inquiry, inquiry freely modified


L-Proline was covalently tethered on thermoresponsive ionic block copolymers that formed
micelles in aqueous solutions. The block copolymers consisted of a poly(N-isopropylacrylamide)
(PNIPAAm) segment and an anionic or cationic polymer segment. These copolymers exhibited lower
critical solution temperature (LCST) behavior at ca. 35-40°C, and achieved thermal stimuli-induced
formation and dissociation of micelles. The copolymer generated micelles in aqueous solution at a
higher temperature, where a catalytic aldol reaction proceeded with high diastereo- and enantioselectivities.
The micelles dissociated at lower temperature to form a clear solution such that the products
could be efficiently extracted from the aqueous reaction mixture. Extraction of the aldol product with
an organic solvent from the aqueous solution of the anionic copolymer was more efficient than from
the nonionic copolymer solution.


A film produced to record A Common Ground to Community House and Garden, a collaboration between students and staff from BA (hons) Interior and Spatial Design at Chelsea College of Arts, A Common Ground designers Something and Son, Tate Britain, Millbank Creative Works and Millbank Estate Moat Community Garden.

Students constructed on The Rootstein Hopkins Parade Ground a mobile community garden from materials recycled from A Commonground, Tate Britain's temporary community garden and invited Millbank local to the garden explore, what role could local green spaces play in bringing communities together?.

A Common Ground to Community House and Garden is part of Chelsea Local, an ongoing project by Chelsea College of Arts, Interior and Spatial Design staff and students working with local communities to cultivate the wealth of local resources, history and the creative potential of Millbank.


The invention discloses an operation system and an operation method for ordering real-name products through the internet. The method comprises the following steps: S1, acquiring data information input by a buyer when the buyer orders a real-name product, wherein identity information of a receiver receiving the real-name product is also received; S2, extracting the identity information of the receiver, and storing the user name of the buyer, product information of the real-name product and the identity information of the receiver in a same list; S3, detecting whether the information of a user of the real-name product is as the same as the identity information of the receiver, and if so, performing the step S4; S4, detecting whether the buyer sends an objection signal after the real-name product is used, and if not, performing the step S5; and S5, establishing a matching relation of the user name of the buyer, the product information of the real-name product and the identity information of the receiver in the list. According to the invention, the complexity of verification information used in operation of online shopping of a user is enhanced, and thus the risk of fraudulent behaviors is lowered.