The paper draws its attention to the roles risk and faith
played in the development of co-production projects between the
East German and Czechoslovak film studios, DEFA and Barrandov.
While focused on the concepts of risk and trust in the 1970s
and 1980s, the conclusions derived from such an analysis
promise to be transferable to other international
co-productions developed under State-Socialism and potentially
even to those of other film industries. The proposed approach
allows us not to restrict ourselves to a hierarchical
relationship between administrative bodies and subordinate
creative personnel though, but rather also to recognize a
horizontal axis characterized by business partners and
ideological allies. The paper focuses on the period of the
1970s and 1980s, when Barrandov remained attractive to DEFA as
a service provider, and Barrandov's management demonstrated
greater interest in collaborating with an ideologically
"trustworthy" DEFA than during the previous, comparatively
liberal, years. Produced by Barrandov's Children's Film
Dramaturgical Group and DEFA's Roter Kreis and Berlin,
fairytales and children's films represented the most reliable,
commercially successful East-German-Czechoslovak co-productions
of the 1970s. They benefited from high levels of shared
institutional trust. This trust was rooted in
professionalization and the corporate culture of the Children's
Films dramaturgical group at Barrandov, as well as in the
personal networks established with partnering DEFA groups. In
the 1970s and 1980s, central dramaturgies saw DEFA and
Barrandov as politically reliable partners. The credibility of
their partnerships, coupled with a comparatively low risk of
failure in this sphere of production, stimulated a relatively
long and commercially impressive run of films.


In their natural habitats, plants have to cope with multiple stress factors triggering respective response pathways, leading to mutual interference. Our work aimed to study the effect of salt stress in combination with immune response triggered by microbe-associated molecular pattern (MAMP) in Arabidopsis thaliana Col-0 plants. We measured ROS production after treatment with flg22 and the influence of concomitant salt stress (NaCl and Na2CO3).The maximum combined effect of NaCl solution and flg22 on ROS production was achieved at 6 mM salt, which was almost 2 times higher than the single effect of MAMP. A similar maximum combined effect with Na2CO3 was observed at 10 mM concentration. High concentration of NaCl and Na2CO3 was accompanied with declining of ROS production, which was completely inhibited at 150 mM of NaCl and at 50 mM of Na2CO3.The immediate and long term (24 h) effect of NaCl on leaf tissue of Arabidopsis thaliana showed that the impact of salt stress on flg22induced ROS production probably did not affect the genetic aspects of the tissue response, but was associated with ionic and osmotic stresses. Experiments with mannitol, KCl and CaCl2 allowed to conclude that the observed effect was due to the ionic stress of the salt rather than the osmotic one.


As the understanding of anatomy and techniques has improved, rotator cuff repair has advanced from single-row to double-row repair. A double-row repair is the current gold standard for restoration of anatomy, biomechanical strength, and postoperative healing. Initial double-row repairs consisted of two independent rows of anchors. The advancement of knotless technology provided the ability to create suture-bridging constructs in which sutures from the medial anchors were secured laterally with knotless anchors to create linked constructs.


Ceramic oxide coatings were fabricated on 7A55 aluminium alloy surface by micro-arc oxidation(MAO) at the constant current density of 6A/dm2 in phosphate electrolyte.The Growth curves,microphotoes,element linear distributions,phase composition and adhesion to the substrate s of the micro-arc oxidation coatings were investigated.The results indicate that the thickness of ceramic coatings increases with increasing of oxidation time,while the growth rates are different during processing.The coating is only a layer and grows towards outer surface mainly.EDX analysis reveals that Al and O as the major constituents are distributed uniformly throughout the coating thickness.The coating is composed of α-Al2O3 and γ-Al2O3,while the γ-Al2O3 phase is high content.Micro-scratch test reveals that there is an excellent adhesion between coating and substrate.


We present computational results of the flow dynamics and forces on a circular cylinder oscillating in-line with respect to a steady uniform stream. A wide range of oscillation frequencies is considered, from 0.5fs to 3fs , where fs is the natural Strouhal frequency of the Karman street. The oscillation amplitude is varied up to half the cylinder diameter. The Reynolds number value is 180, corresponding to two-dimensional flow. Simulations utilize a spectral element method. The computed flow states are characterized based on processed lift signals, and flow visualization. We find that the response of the flow is very sensitive to variations of the cylinder oscillation frequency. At low oscillation frequency, the lift signal and vortex patterns remain regular for low oscillation amplitudes, i.e. correspond to a 2S type of vortex street, and become complex at high oscillation amplitudes. Cylinder oscillation at the Strouhal frequency gives a window of chaotic flow at intermediate amplitudes, while at higher amplitudes 2S wakes are generated, with the sub-harmonic fs /2 and the higher harmonic 3fs /2 dominating the lift spectrum. Oscillation at twice the Strouhal frequency results in symmetric shedding, for oscillation amplitudes close to 30% of the cylinder diameter, and higher. Finally, at an oscillation frequency equal to three times the Strouhal frequency, the flow dynamics is very rich, characterized by "islands" of symmetric and asymmetric shedding at increasing oscillation amplitude. Chaotic flow is obtained only when the excitation frequency is equal to fs or to 3fs .Copyright © 2010 by ASME


In order to guarantee the best user experience throughout different network access technologies with dynamically varying network conditions, it is fundamental to adopt new technologies enabling a proper reception of the multimedia content. In this paper we implemented a prototype of streaming client, based on the MPEG DASH standard. We experimentally evaluated three adaptive streaming algorithms proposed by different authors in order to answer the following questions: (i) how fast is the reaction time to bandwidths changes? (ii) algorithm behavior on a highly unstable network conditions and (iii) buffer underrun/overflow. We identify differences, inefficiencies and possible improvements.


The World Health Organization (WHO) recommends exclusive breastfeeding for the first six months of a child's life. However, while the national coverage was 61.33%, the coverage in Sukoharjo was 39.33%. Effective intervention is needed to promote the importance of exclusive breastfeeding, and this requires knowledge of the barriers and support structures in place. This study analyzed the supports and barriers of exclusive breastfeeding in Sukoharjo, Central Java, Indonesia.,This qualitative study used in-depth interviews conducted from December 2017 to March 2018. The population consisted of 33 informants (29 mothers with babies over six months of age, a pregnant mother, two midwives working in the community health center and a staff member in the district health department).,There were barriers to and support for exclusive breastfeeding in Sukoharjo, Central Java province, Indonesia. The district already has support systems in place, while the barriers emerge from society, the baby's condition, environmental and other sources. The government has tried to overcome the barriers.,The limitation of this study was that the triangulation method was not utilized. However, the use of various informants strengthened the findings.,The district government, especially the health department, needs to establish a program to evaluate existing exclusive breastfeeding support programs thoroughly. Smarter and more comprehensive interventions may be needed, for example, by integrating various supports into one activity. For researchers, the findings of this study imply that they can conduct experimental community research using the framework of the two aforementioned theories of behavior change. For example, investigation of combining the support of trained peers with the presence of family members such as the grandmothers of the babies. If both types of support are conducted concurrently, it may strengthen support and reduce barriers from either inside or outside the home.,The district government, especially the health department, needs to establish a program to evaluate existing exclusive breastfeeding support programs thoroughly. Smarter and more comprehensive interventions may be needed, for example, by integrating various supports into one activity. For researchers, the findings of this study imply that they can conduct experimental community research using the framework of the two aforementioned theories of behavior change. For example, investigation of combining the support of trained peers with the presence of family members such as the grandmothers of the babies. If both types of support are conducted concurrently, it may strengthen support and reduce barriers from either inside or outside the home.,There are barriers to exclusive breastfeeding in Sukoharjo, but the government has made effective attempts to overcome them. The support systems in place were in line with the theory of planned behavior (TPB) and social cognitive theory (SCT).


The desirable properties of a matrix for tissue engineering applications appears to shift from a minimal model of supporting cell growth to a more inclusive role as a matrix to trigger the regeneration process. This requirement has propelled efforts towards bio-functionalization of matrices both by chemical and textural modification of most advanced materials, including silk. Amongst different biomaterials, silk fibroin (SF) has been extensively used for various tissue engineering applications, because of its low immunogenicity and good mechanical strength, although low biological activity and a poor biodegradability rate has remained its major limitation for use in regenerative medicine. In the present study, the physical as well as biological properties of SF have been improved by incorporation of honey, a natural healing agent. Honey-blended SF films (HSF) demonstrated increased mechanical strength together with enhanced wettability, swelling ability and degradability without hampering the original mechanical and biological properties of both honey and SF. In addition, parallel-aligned nanostructures were produced over native SF and HSF using soft lithography to form two-dimensional nano-patterned membranes. HSF films demonstrated enhanced surface roughness in flat membranes and even more so in nano-patterned membranes when compared with native SF membranes which are essential for cellular adhesion and proliferation. Furthermore, biocompatibility and cellular behavior such as adhesion, proliferation, spreading and interaction of 3T3 fibroblast cells were improved using HSF when compared with using native SF membranes. Thus, HSF membranes with enhanced bio-physical properties are a potential material for use in regenerative medicine and tissue engineering applications.


Thermal aging of HVDC Mass Impregnated Polypropylene Laminated Paper (MI-PPLP) cable could reduce the dielectric strength. And degradation of the physical and chemical properties of MI-PPLP could be caused by partial discharge in voids created by cavitation phenomenon. If void discharge is maintained, electrical aging is accelerated at the interface between air void and MI-PPLP, and ultimately dielectric breakdown occurs. There are several reports on the dielectric breakdown and partial discharge characteristics for insulation diagnosis of HVDC MI-PPLP cable. However, studies on the dielectric breakdown and partial discharge characteristics of HVDC MI-PPLP cables considering the thermal aging are insufficient. Therefore, in this paper, breakdown voltage (BDV) and partial discharge inception voltage (PDIV) characteristics are analyzed under the influence of the thermal aging of void defects. since it takes a lot of time to evaluate the insulation performance of MI-PPLP due to thermal aging under normal operating conditions, the thermal aging process was shortened through accelerated aging at 120°C. For reliable experiments, the equivalent lifetime between accelerated aging and normal operating conditions was suggested using the Arrhenius model. Since the Arrhenius model shows the reaction rate according to the activation energy of the specimen, the equivalent lifetime must be derived from the activation energy. The activation energy can be derived by applying the Kissinger method to thermos gravimetric analysis (TGA). From the experimental results, As the thermal aging of MI-PPLP proceeded, decrease in BDV is more severe than PDIV due to the increased Permittivity. Consequently, it is considered that relation between BDV and PDIV characteristics due to thermal aging can be estimated based on the equivalent lifetime obtained through the Arrhenius model.


[Objective] The research aimed to study the biological characteristics and essential oil component of Ocimum basilicum L. in winter under conditions of different fill-in light. [Method] The Ocimum basilicum L. was covered with the film and fill light in winter, analyzed its changes of biomass and the content of essential oil at all growth process, and studied the effects of different fill-in light time on Ocimum basilicum L. at different growth stages. [Result] The results showed that fill-in light was conducive to increase the biomass of Ocimum basilicum L.. The fresh weight per plant of Ocimum basilicum L. up to 740 g and the content of essential oil decreased light by 0.08ml/100g FW under the condition of long fill-in light. [Conclusion] The study can provide the basis for optimizing the cultivating model of Ocimum basilicum L. in winter.


The study is based on the results of multibeam echo-sounding and high-frequency seismic profiling during the 2018-2022 cruises of the R/V "Akademik Nikolai Strakhov" and "Akademik Boris Petrov". Regular changes of morphometric parameters and the internal structure of pingo-like formations of the shelves of the Pechora and Kara seas were revealed. A morphometric analysis of pingo-like formations was carried out, which made it possible to draw conclusions about their relative age, as well as the role of near-bottom currents and slope processes in their modern dynamics. It was found that the density and morphological variety of pingo-like formations depend on the geological and tectonic features of the bottom area, the presence and nature of permafrost, the intensity of degassing, and the time of shelf flooding during the Holocene transgression. Pingo-like formations on the shelf, where the depth exceeds 70-80 m, emerged at the early stages of the Holocene transgression, and by now the permafrost there has largely thawed out. At the same time, pingo-like formations are still prominent in the relief and actively transformed by bottom currents, slope and, possibly, pseudovolcanic processes associated with ongoing degassing. Pingo-like formations are rare within shallow (up to 20-30 m) shelf areas close to the shore, and, apparently, continue their evolution at present. At the same time, the large thickness and continuity of permafrost prevent active fluid flow, acting as a seal. Pingo-like formations in the shallow-water zones are mainly cone-shaped mounds without intensive degassing. The density of pingo-like formations is maximum at the intermediate depths (from 20-30 to 70-80 m), in the presence of insular or discontinuous permafrost, under high fluid flow intensity within the fault zones and oil- and gas-bearing structures. Near-surface sediments in such areas are characterized by a combination of localized processes of heaving and active degassing. It predetermines a wide variety of the morphological types of pingo-like formations.Keywords: Arctic, bottom topography, degassing, pingo-like features, acoustic anomalies, multibeam echo sounding, seismoacoustic profiling


Background: The study aimed to determine the presence of publication bias in the top five dental journals with high impact factor published during 2007–2016. Materials and Methods: The journals included are Journal of Clinical Periodontology, Dental Materials, Clinical Oral Implant Research (COIR), Journal of Endodontics, and Journal of Dental Research (JDR). The content of these journals was hand searched by two authors for scouring the proportion of positive or negative results. Articles showing two outcomes (primary and secondary) were registered depending on the primary result. Results: The present study revealed higher percentage of statistically significant results in the published dental literature. Of five journals, JDR has shown fewer tendencies toward publication of nonsignificant results, whereas COIR has evidenced the highest publication of nonsignificant results. The journals with higher impact factor showed significantly different acceptance rate for research with positive results. However, year-wise publication (2007–2016) did not depict any significant difference. Conclusion: In dental research journals, articles with positive results are finding a better way in getting published compared to articles with negative results.


A communications manager (405) receives messages from a first call feature server (210-A) and sends messages to a second call feature server (210-B). The messages comprise telephony signalling suitable for use over a time division multiplexing (TDM) telecommunications signalling channel. An emulation manager (420, 430, 440) is also provided. The emulation manager is coupled to the communications manager (405) and is arranged to receive messages from the first call feature server (210-A) via the communications manager (405), emulate one or more TDM telecommunications signalling channels for communication of said messages, and send messages to the second call feature server (210-B) via the communications manager (405).


Responsible fatherhood legislation bridges the gap between two explicit family policies in order to serve fathers: The Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) of 1996 and the Child Support Enforcement Act of 1975. Historically, these two polices have been racialized and discourse surrounding them may contribute to negative cultural formula stories about the primary targets of responsible fatherhood programs: low-income Black fathers. The first article addresses the question of whether and how congressional discourse disrupts or legitimizes negative cultural formula stories about Black fatherhood. This study examines congressional discourse during hearings on fatherhood legislation. Members of congress legitimized cultural formula stories by constructing welfare fathers as deadbeats. Primary themes included serial illegitimacy and parental abandonment. Members of congress also disrupted cultural formula stories by constructing welfare fathers as dead broke. The second article addresses the same question, but it is asked of the first Black President of the United States, Barack Obama. Presidential statements surrounding the unconcerned Black father served to reproduce negative cultural formula stories of Black fatherhood by depicting this kind of father as lazy, prone to fathering children with multiple women (serial illegitimacy), and disinterested in fatherhood overall. The institutionalized Black father embodies negative characteristics but his absence and instability stems from historical oppression and socioeconomic disadvantages. In addition, it changes the single story often found in negative cultural formula stories of Black fatherhood. Lastly, the self-sacrificing Black father embodies Obama's ideal characteristics of Black fatherhood by working tirelessly and sacrificing his own well-being for the betterment of his family. The third article compares congressional and presidential discourse to better understand interpretive conflicts in the meanings of responsible fatherhood. Both members of congress and President Obama presented some negative cultural codes in their discourse on fathers. For members of congress, a large-scale demonstration project conducted with low-income, nonresidential, non-custodial fathers helped to shift their cultural formula stories. On the other hand, President Obama's in-group status allowed him to construct a more diverse spectrum of Black fatherhood. ©2019 by Azaliah B. Israel All Rights Reserved Acknowledgements The completion of this dissertation has been the most laborious, cumbersome, and dramatic task that I have ever undertaken. It is one that will likely only be surpassed by the birth of my first child (whenever that is). As my forefather David exclaims, "It is good for me that I have been afflicted; that I might learn thy statutes (Psalms 119:71). All praises to the Most High God for proving me and finding me worthy of the title "Dr. Israel". All praises for the Saviour whose sacrifice has strengthened me a thousand times over during this journey. An abundance of gratitude to the sons of God who have restored my faith in Black manhood and have given me a reason to hope. Every thanks imaginable to my enduring sisterhood. The books are being written. Know that you have a place in my story. Azarayah, Abygail, Ahavah, Judith, Anat, Iscah, Elizabeth, Kaniyah, Yahara, JoAnna, Zara, Semira, Aviyah, Anaiah, Zion, Zipporah, Keziyah, Ramiah, Yocheved, Neziyah, Reu, Anavah, Odiyah, Vanniah, Akiva, Gemariah, Gabby, Amina, Amaziyah, *Jaazah, Kyra, Leah, Alliyz, Candace, Esther, Zibiyah, Ada, Atara, Shiphrah, Faiza, Jessica, Shiphrah, Ohanna, Yofee, Roni, Jael, Monica, Zaharah, Aliza Raya, Brittany, Melissa, Kathryn, and Cresha. I have had so much support that I have undoubtedly missed some names. The angels have a better memory than me. Your works are recorded sis. Shout out to the Panera Bread franchise and the Metro Northwest Oklahoma City public library that provided the tranquility I needed while living away from my home institution during the completion of this project. These two physical spaces more than any others contributed to my mental clarity while writing. Monday motivation from Dr. Eric Thomas and green tea Frappuccinos from Stella Nova are two things I couldn't go without. To my committee chair, Dr. Anna Zajicek, thank you for your mentorship and for having high expectations for me and my work. You have witnessed the very best times of my life and some of the worst. I will not forget that you remained supportive throughout it all. To my committee members, Dr. Yvette Murphy-Erby and Dr. Ed Bengtson, thank you for valuable feedback and your patience throughout this process. The greatest fear of a Doctoral candidate is an adversarial and difficult committee. I experienced the exact opposite of that. My interactions with you have helped to transform me into an independent scholar. Dedication For the earnest expectation of the creature waiteth for the manifestation of the sons of God. Romans 8:19 To my fathers and brothers scattered throughout the four corners The World waits on you


In this particular study the problem is to determine the influence working after school hours has upon a group of junior high school boys. This study is concerned with comparisons in subject matter achievement, self and social adjustment, and behavior records and ratings. It is the purpose of this study to make these comparisons with boys who work after school and those who do not.


Projection is a defence mechanism involving the expulsion of unwanted or unbearable parts of the personality, which are then located in others and thereby disowned. My aim in this essay is to explore the development of theoretical ideas about projection, and how they have affected contemporary theories of psychoanalytic practice. I shall illustrate the application of some of these ideas using two case examples.


In recent years the number of IoT devices in businesses has significantly increased, which creates an undeniable challenge for network administrators and industries to identify and monitor the heterogeneous IoT environment. Also, identifying IoT devices helps organizations resolve several security dilemmas, such as determining if connected IoT devices' behaviour is compromised or not. In this work, we propose a distributive profiling mode to distinguish between IoT and non-IoT devices, map devices, identify the network that devices are attached to, and then continuously update the profile. Using a hybrid set of features and 23 new proposed features for identifying IoT devices, our method improves accuracy and shorter training time compared to other existing methods. Our proposed approach experiments with 18 Machine Learning (ML) classifiers on three publicly available datasets, i.e., IoTSentinel, UNSW, LSIF. Our study shows that Random Forest (RF) and Decision Tree (DT) classifiers outperformed the other ML classifiers by achieving an average accuracy, precision, recall, and f1-score above 90% with a shorter training time. This shows that our proposed system is suitable for providing a more generalized solution for profiling IoT devices.


High-temperature annealing is necessary in a number of applications for III-nitrides, including activation of Si+ or Mg+ implants for doping, maximization of implant-isolated regions, and Ohmic contact sintering. We have compared two methods for protection against surface dissociation of GaN, AlN, InN, InxGa1−xN, and InxAl1−xN during rapid thermal processing in N2 ambients. In the first method, AlN or InN powder is placed in the reservoirs of a SiC-coated graphite susceptor and provides a N2 overpressure for the nitride samples within the susceptor. In the second method, the nitrides are placed face down on other III–V substrates during annealing. In both techniques N loss from the nitride surface is found to occur at ⩾1050 °C for GaN and ⩾1100 °C for AlN and ⩾InN, as measured by Auger electron spectroscopy. Real surface roughening is generally significant only for the In-containing materials, with GaN and AlN retaining smooth morphologies even up to 1150 °C unless H2 is present in the annealing ambient. When InN powder is used in the susceptor, there is In droplet condensation on the surfaces of all samples above ∼750 °C leading to higher root-mean-square surface roughness measured by atomic force microscopy. The N2-deficient surfaces of the binary nitrides become strongly n type, while those of ternaries become less conducting. At temperature of 850–900°C, the In droplets on thermally degraded ternaries also begin to evaporate, leading to an apparent improvement in morphology. The presence of H2 or O2 in the annealing ambient lowers the dissociation temperature of each of the nitrides by 100–200 °C, due to an enhancement in N2 removal.High-temperature annealing is necessary in a number of applications for III-nitrides, including activation of Si+ or Mg+ implants for doping, maximization of implant-isolated regions, and Ohmic contact sintering. We have compared two methods for protection against surface dissociation of GaN, AlN, InN, InxGa1−xN, and InxAl1−xN during rapid thermal processing in N2 ambients. In the first method, AlN or InN powder is placed in the reservoirs of a SiC-coated graphite susceptor and provides a N2 overpressure for the nitride samples within the susceptor. In the second method, the nitrides are placed face down on other III–V substrates during annealing. In both techniques N loss from the nitride surface is found to occur at ⩾1050 °C for GaN and ⩾1100 °C for AlN and ⩾InN, as measured by Auger electron spectroscopy. Real surface roughening is generally significant only for the In-containing materials, with GaN and AlN retaining smooth morphologies even up to 1150 °C unless H2 is present in the annealing ambient. ...


This invention relates to a system of ankle support (10) COMBINED WITH FOOTWEAR (23) A TABLE OF SNOW IS USED IN EXTREME CONDITIONS ARE NOT. THIS SYSTEM (10) comprises a cup RIGID HEEL (12) and a backplate HIGH (16) ALLOWING THE REGION ATTACH CALF ATHLETE. THIS REAR SUPPORT ELEVATED (16) comprises an extension element 818), which has an end portion BACKGROUND AND ENGAGED IN A BAG IS 814) formed in the rear and HIGHER HEEL CUP (12). LINK THIS ALLOWS THE REAR SUPPORT ELEVATED (16) FLOAT AROUND A pivot axis can move in translation and over a predetermined distance along transverse axes, longitudinal and vertical support system ANKLE (10). Articulation ANKLE support device is done in a very similar manner to the foot and ankle ATHLETE. A NAKED THREAD (20) Avoids CUALQUIERDESPLAZAMIENTO BY NEGLECT REAR SUPPORT BETWEEN HIGH (16) and the cup TALON (12). TENSION CORD (22) adjustable length also ensures the system setting (10) During a forward bend.


To the Editors:

Abt–Letterer–Siwe syndrome, which is a disseminated form of Langerhans' cell histiocytosis (LCH), was diagnosed in the patient at the age of 6 months, affecting the inguinal lymph nodes and skin, and recurred at the age of 21 yrs, affecting lungs and arcus pubis 1. After two chemotherapy sessions, including vinblastine, etoposide and corticosteroids, complete remission was reached. At the age of 25 yrs the first high-altitude oedema occurred during a ski vacation at 2,400 m followed by the second episode 3 yrs later at an altitude of 2,800 m, which was confirmed by chest radiograph. After the second episode of high-altitude pulmonary oedema (HAPE) the patient was referred to the Division of Sports Medicine at the University Hospital of Heidelberg, Heidelberg, Germany, where he was assessed as described before 2. Estimated systolic pulmonary artery pressure ( P pa) was normal at rest (25 mmHg), increased to 50 mmHg after 30 min (oxygen saturation 74%) and to 60 mmHg (saturation 65%) after 90 min of exposure to normobaric hypoxia (inspiratory oxygen fraction ( F I,O2) of 12%). Stress Doppler echocadiography revealed systolic P pa values up to 95 mmHg during normoxic exercise of 125 W. The patient had a normal systemic blood pressure at rest and during exercise and no signs of left ventricular dysfunction. Maximum exercise capacity was 1.95 W·kg−1 (70% of normal), maximum oxygen consumption ( V ′O2) was 2.6 L·min−1 (80% of normal), body plethysmography showed patterns of obstructive and restrictive lung disease (airway resistance 158% of normal, forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio was 60% (70% predicted), vital capacity was 70%, residual volume 166%, total lung capacity 95%) and a reduced diffusion capacity for carbon monoxide (48% pred). Despite shortness of breath, the …


Nonimmune hydrops fetalis (NIHF) has varied etiology. We assessed the etiological spectrum and evaluated the utility of fetal whole exome sequencing (fWES) for the diagnosis of NIHF.


Cob brick is called Huji(胡墼) in Northern Chinese dialect.It is a native word but not a loan word.The original meaning of Huji(胡墼) is hard piece of soil and I try to prove that Hu(ifi) keeps Tu(土)'s voice ofXia(匣) initial and Mo(模) final.


Background/Objectives: There has been a growing interest in the antimicrobial activity of natural extracts that inhibit the growth of microorganisms without side effects. Therefore, we evaluated the antibacterial effects of cinnamon oil against oral microorganisms existing in dental plaque.Methods/Statistical analysis: Dental plaque was formed on bovine specimens using a growth medium for 6 days, followed by treatment with either 2.5% cinnamon oil, 0.12% chlorhexidine gluconate, or 10% dimethyl sulfoxide for 5 min, twice per day. On day 7, each specimen was imaged using quantitative light-induced fluorescence–digital to assess microbial activity of dental plaque. A one-way analysis of variance and the Scheffe post hoc test were performed to analyze the differences in red/green ratio (R/G values) of dental plaque between the three treatment groups.Findings: The average R/G values of dental plaque was the lowest in the 2.5% cinnamon oil group (1.180 ± 0.010), and these values were significantly different from those of the chlorhexidine gluconate group (1.249 ± 0.008) (p<0.001). Furthermore, the changes in the mean R/G values of each specimen showed statistically significant differences over time (p<0.05). Thus, we suggest that cinnamon oil is an effective antimicrobial agent that inhibits the proliferation of anaerobic bacteria in dental plaque.Improvements/Applications: Further studies should compare and analyze the antimicrobial activity of cinnamon oil against oral microorganisms at different concentrations.


MR. CARSWELL: Previous speakers have described in some detail the extraordinary net of laws and regulations that the Congress and our small army of federal and state bank regulators have woven in the last few years as a response to the equally extraordinary growth in the international financial and banking markets. Most of the substance of this regulation derives from a decision to retard the internationalization of theose markets by requiring new entrants to play in the U.S. by our domestic rules rather than addressing possible changes in those rules to give domestic banks more freedom to compete against foreign entrants. Since our domestic rules are complex, the technically competent response produced is, not surprisingly, even more complex.


Two bioassays were administered to determine the dose-lethality response of Varroa jacobsoni Oudemans and the honey bee, Apis mellifera L., to amitraz, flumethrin and fluvalinate. The first bioassay method was spraying by means of the Potter-Bourgerjon's tower. The results are expressed in mean lethal concentrations (LC50). The second method was topical application by means of microsyringe and manual applicator. The results are expressed in mean lethal doses (LD50). Both LC50 and LD50 values were considerably higher in honey bees than in varroa mites, showing that a wide margin of safety exists between effective doses against mites and harmful doses for honey bees. Both methods gave similar confidence intervals; they showed a comparable sensitivity to changes in dose or concentration of pesticides.


The goal of this work was to develop and study the use of a diagnosticin vivo tissue spectroscopy system based upon frequency‐domain light measurements. Intensity‐modulated light which is incident upon a scattering sample creates waves of light intensity which propagate through the medium in a manner which is dependent upon the scattering and absorption characteristics of the tissue. These waves can be used to recover these optical interaction parameters using a diffusion model of light propagation in tissue. This method can be used to quantify chromophores for dosimetry in therapeutic laser treatments or for diagnosticmedical applications. The theoretical modeling for diffuse fluorescence signals was also developed and experimentally tested in a tissue‐simulating phantom with excellent agreement, suggesting that fluorescence lifetime or quantum yield can be made from tissue. Preliminary work was done on an optical tomography algorithm using measurements of phase and intensity at multiple points on a tissue surface to reconstructimages of the optical properties of the interior. The development of a tomographic imaging system was examined in the final section of this thesis with data from a tissue simulating phantom.


1. An organic electroluminescent display device, comprising: a first substrate; a second substrate facing the first substrate, the organic EL element formed on the first substrate and provided between the first substrate and the second substrate, a sealing member provided between the first substrate and the second substrate and adapted possibility of bonding the first substrate and the second substrate together to insulate the organic EL element; igermetiziruyuschuyu resin formed on the second substrate provided between the first substrate and the second substrate and adapted to cover the surface of the organic EL element, the sealing element and the sealing resin are separated from each other in the direction of the organic EL device otobrazheniya.2 plane. An organic electroluminescent display device of claim 1, the ratio kotoromustanovleno 0,5L + 0,1T≤E≤50T, where T - is the thickness of the sealing resin, E - the distance between the sealing element and the sealing resin in a plane direction, and L - sealing width elementa.3. An organic electroluminescent display device according to claim 1 or 2, wherein the thickness of the sealing resin is in the range from 1 micron to 100 microns inclusive vklyuchitelno.4. Organic electroluminescent display according to claim 1 or 2 device, wherein the sealing resin formed of the resin, ultraviolet curable svetom.5. An organic electroluminescent display device according to claim 1 or 2, wherein the sealing resin will form


Mobile Mapping Systems have been widely used to map transportation infrastructure features for several years. The data acquisition objective of these surveys is typically twofold: to collect an inventory of various, mostly man-made, objects and then to position them in a local frame. First generation Mobile Mapping Systems, however, could not provide positioning accuracy better than one meter, especially in built-up urban areas. Thus, these data sets have been predominantly used to feed various GIS systems, primarily concerned with infrastructure inventory and facility management. With recent technological developments such as improving imaging sensors and, more importantly, the introduction of ring-laser gyro inertial systems, the performance of current Mobile Mapping Systems can reach the cm-level, which, in turn, opens up the field of the engineering applications, which are more demanding in terms of positioning requirements. The Ohio State University is currently developing a GPS/INS/CCD integrated system for precise (centimeter level) monitoring of highway center and edge lines, sponsored by the Ohio Department of Transportation. The prototype-positioning component of the system is based on a tightly integrated GPS/INS system, and the imaging component comprises a single downlooking high-resolution, 1K by 1K, digital camera. The high image rate (up to 15 frames per second) provides sufficient overlap of the subsequent images at highway speed, and thus, it allows for stereo data processing, which, to a large extent, is expected to be performed in realtime with the support of on-the-fly navigation solution. The focus of this paper is on the design, calibration, and preliminary performance analysis of the prototype system. The application of the navigation data to real-time image processing represents a new approach. The process of automatically identifying centerlines, extracting image features and matching them is demonstrated on a variety of data sets, indicating clearly that the algorithmic performance has reached a sufficient threshold such that human interaction is no longer required, and consequently, the only limiting condition of the real-time implementation is the available computer processing power.


Controlling the shape of crystals is of great practical relevance in pharmaceutical manufacturing. In the present study, an attempt was made to correlate experimental and simulated crystal habits of nifedipine (Nif). Modified habits with isodiametric morphology were observed in the following solvent and solvent/antisolvent pairs; chloroform/hexane, chloroform/isopropyl alcohol (IPA), dichloromethane (DCM), DCM/IPA, and ethanol/hexane. Presence of any solvates or polymorphs was ruled out by using differential scanning calorimetry, thermogravimetric analysis, Fourier transform infrared spectroscopy, and powder X-ray diffraction. A solvent effect was introduced by surface docking to bridge the gap between experimental and simulated habits as they deviated from vacuum morphology. Molecular dynamics was performed, and modified attachment energy was calculated to obtain the final morphology. The achieved predictions were found to be in good agreement with the experimental habits (statistically significant with ...


It is not suggested that penicillin alone was responsible for the happy issue. It is well recognized that the immunity responses may so alter that the outcome of such an illness may well transpire to be other than that first envisaged. Nevertheless I am convinced that penicillin in this instance achieved all that was expected of it, whereas in comparable illnesses of previous outbreaks the intensive use of sulphonamides failed to prevent several fatalities. With the probability of further virulent smallpox reaching our ports, it may well fall to others to confirm the impressions gained from the treatment of this patient. M. A. FOULIS, M.D.. Senior Assistant Physician and Surgeon, and Deputy Superintendent. Robroyston Auxiliary Hospital, Millerston.


The utility model discloses a tilter for a large-scale wind power gearbox, which comprises two stands, two slipping components, two T-shaped tilting components, an L-shaped tilting component and the like, wherein the two slipping components are respectively mounted on the two stands; the two T-shaped tilting components are respectively fixed on the two slipping components; and the two ends of the L-shaped tilting component are respectively connected with the two T-shaped tilting components. The tilter is applied to the assembly line of large-scale wind power gearboxes, has a maximum carrying capacity of 50 ton, is reasonably designed to solve the eccentric problem in the large-scale wind power gearbox, and aims to achieve the effect that the gravity center of the entire large-scale wind power gearbox is positioned at the geometric centre thereof in the tilting process of the large-scale wind power gearbox. Meanwhile, the tilter has the advantages of small energy consumption, high work efficiency, good adaptability, work reliability and easiness in operation, and can be used for tilting products of various models by changing part clamps.


In this study the immobilization of lipase in matrices produced with gelatin with different Bloom values and with the addition of plastifiers was investigated to evaluate the influence of the Bloom value, as well as the capacity of the plastifiers to maintain the enzyme immobilized and the immobilization yield. The results indicated the need for crosslinking of the matrices with glutaraldehyde due to the high solubility in water, explained by the amino acid profile, which confirms the solubility of gelatin. Mannitol showed greater efficiency in the lipase immobilization, since it led to more porous structures and more uniform pores. These structures were also influenced by the gelatin concentration; greater concentrations associated with intermediate concentrations of plastifier led to matrices with a greater immobilization yield (87.92%). The   X-ray diffraction analysis revealed that the structure of the immobilization matrices was partially crystalline.


● n°16 décembre 2006 The proper meaning of the term "Neolithic" has been much discussed in the African context during the last decades, although most scholars agree today that it is more necessary than ever to define it carefully before applying it, if it should be applied at all. European-trained prehistorians have been tempted to use this term for the earliest presence of polished stone tools, pottery, cereal agriculture and herding wherever they work. It is clear, however, that this rather outdated concept of "Neolithic" cannot be transferred uncritically from the European or Middle Eastern scenes to the African continent (Sinclair et al. 1993: 6-8). In north-east Africa, where a pastoral component with cattle herding was prominent from the beginning of the Neolithic, there is naturally some lack of concordance between the French and the anglophone terminology. On the whole, however, "Neolithic" is considered equivalent to "food production" in one form or another. As substitutes for or additions to that term there are different and, in most contexts, more precise designations such as "pastoral", "agricultural" or "agro-pastoral". Nevertheless, the modern multi-disciplinary emphasis on economy, ecology and settlement strategies is obvious in all camps, while the presence or absence of pottery or of specific lithic technologies, or of traces of long-term habitation are optional. In the spirit of processual archaeology it is essential to continue to analyse, insofar as the available data permits, parameters other than the economic or technological in order to fully understand the transformation from a hunter-gathering to a food producing society (Sinclair et al. 1993: 8; Edwards 2004: 56-57). These issues were not on the agenda when I came to Nubia in April 1960 to take part in the International salvage campaign as a Unesco programme assistant attached to Sudan Antiquities Service and the small team lead by W. Y. Adams. In Nubia up to that time most of the archaeological work and discussions had been centred on the relations between Pharaonic Egypt and the Nubian province. From the beginning of the 20th century the archaeological field strategies had to a large extent been directed towards the finding and exThe discovery of the Neolithic in Nubia


Inelastic light scattering from electrons is a symmetry-selective probe of the charge dynamics within correlated materials. Many measurements have been made on correlated insulators, and recent exact solutions in large dimensions explain a number of anomalous features found in experiments. Here we focus on the correlated metal, as described by the Hubbard model away from half filling. We can determine the B1g Raman response and the inelastic x-ray scattering along the Brillouin-zone diagonal exactly in the large dimensional limit. We find a number of interesting features in the light-scattering response, which should be able to be seen in correlated metals such as the heavy fermions.


Non steroidal anti-inflammatory drugs may influence the osteoarthritis process osteoarthritis is a dynamic, metabolically active remodelling process with potential to compensate for a variety of triggering insults. NSAIDs may variably influence several aspects of cartilage metabolism


An analysis of databases of photographic images of ocean's surface, taken from various altitudes and for various types of rough ocean surface, revealed the presence of an ocean's skeletal structures (OSS). We make a stress on the phenomenon of OSS's blocks in the form of vertically oriented floating cylinders (VFC) because here we suggest the hypothesis that the VFC is a stimulator of initial phase of the "waterspout" phenomenon (WS). An analysis of the fine structure of VFC suggests the OSS to be a carrier/source of major electrodynamical properties of initial phase of every WS. This implies that the main body of WS may be interpreted as a special type of atmospheric aerosol dusty plasma. In such a framework, the WS is considered as the long-lived filament, being formed in electric discharge in the presence of electric and magnetic fields in the course of electric breakdown between the cloud and ocean surface. In this case the charged water aerosol (formed by means of VFC's capillaries in the presence of very powerful electric field) may be an analog of a microdust which is lifting upward to the cloud due to effects of electrostatic forces. With such a capillary-electrostatic model of WS, it appears possible to interpret many effects related to WS. We suggest a hypothesis for dynamics of WS and a possible scenario of its transition to classical tornado.


Objective
To construct a recombinant Bacillus Calmette-Guerin (BCG) vaccine strain, rBCG: : Rv3478-pMV261, expressing the Rv3478 protein of Mycobacterium tuberculosis and to investigate its immunogenicity.

Methods
The gene fragments encoding Rv3478 antigen were amplified by PCR and then respectively cloned into pMV261 and pET-28a vectors to construct the recombinant expression plasmids (Rv3478-pMV261 and Rv3478-pET-28a). The Rv3478-pMV261 plasmids were transformed into the BCG cells to construct the rBCG vaccine strains, while the Rv3478-pET-28a plasmids were transformed into Escherichia coli BL21 strains for the expression of Rv3478 protein. Polyclonal antibodies were induced in mice upon the immunization with Rv3478 protein. The rBCG vaccine strains overexpressing Rv3478 protein were screened out with Western blot assay. The C57BL/6 mice were divided into four groups including the PBS treated group, BCG treated group, rBCG: : pMV261 (R0) treated group and rBCG: : Rv3478-pMV261 (R3) treated group. All mice were sacrificed in 4 or 12 weeks after immunization. Enzyme-linked immunospot assay (ELISPOT), ELISA and flow cytometry analysis were performed to evaluate the induced humoral and cell-mediated immune responses in mice.

Results
The Rv3478 protein was successfully expressed and could induce polyclonal antibodies in mice. High levels of IFN-γ and TNF-α were detected in mice treated with R3, indicating that the immunization with R3 enhanced the cellular immunity. Moreover, the ratios of CD4+ to CD8+ T cells and the percentages of CD44+ CD62L+ T cells were increased in mice upon the immunization with R3.

Conclusion
The recombinant BCG vaccine strain overexpressing Rv3478 protein could induce stronger cell-mediated immune responses in mice. It might be have a great significance as a new tuberculosis(TB) vaccine strain against TB infection in the future.

Key words:
Tuberculosis; Recombinant BCG; Rv3478; Vaccine


1Student M.E. (Civil-STRUCTURES), Department of Civil Engineering, N.B.N.Sinhgad College of Engineering, Solapur, Maharashtra, India. 2Assistant Professor, Department of Civil Engineering, N.B.N.Sinhgad College of Engineering, Solapur, Maharashtra, India. --------------------------------------------------------------------***---------------------------------------------------------------Abstract: Energy plays a crucial role in growth of developing countries like India. To save energy and to earn carbon credit is very much essential for the betterment of mankind. Now a day there is low availability of non-renewable energy resources, and also large requirements of Building Construction Materials like cement, etc.. The global cement industries contributes about large amount of greenhouse gases emission to earth's atmosphere and industrial waste are being produced Largely by chemical process in the India. In order to reduce cement manufacturing and disposal problem of paper waste, there is need to develop alternative binding material in construction field. Utilization of paper industry waste product as supplementary cementitious material in concrete is very important aspect in view of economical, environmental and technical reasons. This paper summarizes that the research work on the behavior of concrete while adding of hypo sludge with different proportion as part replacement of cement in concrete by using test like Compression strength test, Split Tensile Strength test and Flexural Strength Test. The experimental investigation gives results that the test results are increasing their strength values up to some initial Percentage replacement of cement by Hypo sludge and further replacement are carried out then strength results are falling down.


Several cases of increases in frequency of mood cycling have recently been reported in women as a result of tricyclic antidepressant treatment (Siris et al, 1979; Wehr and Goodwin, 1979). We report here the occurrence of 48-hour rapid cycling in a man with recurrent unipolar depression after treatment with dibenzepin (Noveril), an atypical tricyclic antidepressant. Alterations in urinary cyclic adenosine monophosphate (AMP) have been reported with mood changes and were therefore evaluated at the same time.


The liquid-phase catalytic oxidation of cyclohexene to produce cyclohexenol and cyclohexenone directly was attempted using Mn ion substituted in ceria in acetonitrile solvent with 30% H2O2 as oxidant under atmospheric pressure. Structural studies by XRD show indication of ionically dispersed metal over ceria. Among all the catalysts studied, the Mn0.05Ce0.95O2−δ catalyst prepared by the solution combustion method has shown more activity (95.3% conversion with 98.7% selectivity) than others. The influences of the amount of Mn loading, temperature, time, the concentration of H2O2 and solvent have also been investigated. The enhancement of activity in Mn2+ ion substituted ceria as compared to other catalysts has been attributed to Mn–O–Ce ionic interaction in the combustion synthesized catalyst. Ionic substitution also helps to get an active stable catalyst with lower risk of Mn-leaching compared to the impregnated catalyst.


The present invention relates to a production method of sandwich filling with excellent functionality and storage properties by fermenting vegetables in mixed dipping liquid containing natural spices and enzymatic processing liquid. The sandwich filling produced by the method of the present invention can be stored for a long time while maintaining nutrients of the vegetables, offers excellent functionality by uniformly soaking the vegetables in natural spice components, and enables busy modern users to apply the sandwich filling to sandwiches. [Reference numerals] (AA) Manufacture the hot water extract of natural spices; (BB) Manufacture enzymatic processing liquid; (CC) Vegetable blanching; (DD) Ferment and age the vegetables; (EE) Mix the vegetables, salad sauce, and starch


Background: Inflammatory Bowel Disease (IBD) is a chronic condition often diagnosed at a young age without a cure, requiring a lifetime of medical care. Given this, IBD can lead to significant health, lifestyle and cost burdens to patients, their families and society. Several healthcare organizations have created performance measures to aid in establishing evidence-based standards of care in attempts to improve the quality of IBD care, and ultimately health outcomes. The Physician Quality Reporting System (PQRS) has defined 7 performance measures which apply to outpatient IBD care, including: management of patients with corticosteroid sparing therapies, documentation of risk for corticosteroid related iatrogenic bone injury, documentation of prior or administration of the influenza vaccination, documentation of prior or administration of the pneumonia vaccination, testing for latent TB before initiation of anti-tumor necrosis factor (anti-TNF) therapy, testing for hepatitis B status before initiation of anti-TNF therapy and screening and cessation interventions for tobacco abuse. The aim of this study was to assess documentation compliance with selected PQRS performance measures at one academic medical center and gastroenterologists' self-assessment of their personal compliance. Methods: Fifty IBD patient charts were randomly selected from consecutive outpatient IBD visits at our medical center from January 9, 2015 to June 30, 2016. These charts were reviewed to assess compliance levels with PQRS performance measures for outpatient IBD care, except management of corticosteroid sparing therapies. In addition, an online physician survey was conducted to anonymously assess gastroenterologists' perceived compliance with these measures. Results: Of the 50 patients, 11 met criteria for being at risk for bone loss related to steroid use. Zero of the 11 (0%) patients' charts had documentation of bone loss assessment evaluation. Thirty-six of the patients were seen during flu season and 7/36 (19.4%) of those received the influenza vaccine, refused the vaccine or had chart documentation of prior receipt of the vaccine. Only 8 of the 50 charts reviewed were patients 65 years of age or older and zero (0%) of those received the pneumonia vaccine, refused the vaccine or had chart documentation of prior receipt of the vaccine. Only 3 of the charts reviewed were within 1 year of initiation of ant-TNF therapy. Of these, 2/3 (66.7%) had documentation of testing for latent tuberculosis and 3/3 (100%) had documentation of assessment of hepatitis B virus prior to initiation of anti-TNF therapy. All 50 patients had been screened for tobacco use with 7/50 being active smokers. Of those, 2/7 (28.6%) received a tobacco cessation intervention. Seven out of 13 physicians surveyed (53.8%) felt that they often complied with the PQRS performance measures with IBD patients in the outpatient setting. However, when asked if they complied with documentation of those same performance measures, only 5/13 (38.5%) felt that they often documented their compliance. Conclusions: Documented compliance with several PQRS performance measures for outpatient IBD care is low at our medical center. Most gastroenterologists feel confident that they clinically comply with these performance measures, but often their documentation does not reflect this.


This study examines the role given to alcohol in the context of the bohemia lifestyle as it developed in Madrid in the years 1885–1920. Alcohol consumption was a major element in the construction of the conflictual identity of the bohemio: it was without exception an excessive and pathological consumption leading to alcoholism rather than drunkenness. For the bohemians, alcohol functioned as a sign and as a mechanism. It was a sign of identity in their transgression of bourgeois codes relating to the body, morals or accepted behaviour. Alcohol consumption is also instrumental in their own social marginality and their identification with certain sectors of the working class. The bohemian subculture in Madrid developed a tragic relationship to alcohol, which was linked ultimately to a self-destructive drive. Hence their sense of guilt and their neurotic attitude towards the massive intake of alcohol: it hindered the aesthetic efficacy of their creative work instead of enhancing their poetic energy. Alcohol ...


Abstract Hunzinger Construction University (HCU) was founded in 2000 to provide quality continuing education and field training for Hunzinger Construction employees and outside guests. In August 2008, Hunzinger Construction University and its leaders were awarded the Green Educator of the Year Award from Wisconsin Builder Magazine. The University organizes over 70 continuing education opportunities per year and continues to expand its offerings. Classes offered cover topics such as sustainability, green building and the LEED® Rating System, safety, business acumen, construction materials and new products, design and construction methods, health and wellness, crisis management, first-aid and CPR, cooperation and conflict management, self improvement, financial management, business writing and presentation skills, time management, situational leadership, jobsite productivity and delivering persuasive presentations. Due to the growth of HCU and the need to expand Hunzinger Construction Company's yard, wareho...


(57) Abstract: OBJECTIVE increased movement of temporary roof covering the upper portion during construction of Concrete building frame is to smoothly performed so. [Configuration] erected a plurality of telescopic struts 1 outside the building St. to building frame, bridged temporary roof 2 which covers the top of the building frame A to the upper end of the post 1 group, the upper portion of the precursor A in the temporary roof 2 together also allow construction in the rain by covering, the telescopic strut 1 is extended with the progress of the skeleton, intermittently raises the temporary roof 2.


PurposeThis paper presents a critical review of studies which map the urban environment using continuous physiological data collection. A conceptual model is consequently presented for mitigating urban stress at the city and the user level.Design/methodology/approachThe study reviews relevant publications, examining the tools used for data collection and the methods used for data analysis and data fusion. The relationship between urban features and physiological responses is also examined.FindingsThe review showed that the continuous monitoring of physiological data in the urban environment can be used for location-aware stress detection and urban emotion mapping. The combination of physiological and contextual data helps researchers understand how the urban environment affects the human body. The review indicated a relationship between some urban features (green, land use, traffic, isovist parameters) and physiological responses, though more research is needed to solidify the existence of the identified links. The review also identified many theoretical, methodological and practical issues which hinder further research in this area.Originality/valueWhile there is large potential in this field, there has been no review of studies which map continuously physiological data in the urban environment. This study covers this gap and introduces a novel conceptual model for mitigating urban stress.


The microXAS beamline is a dedicated hard X-ray microprobe facility allowing a combination of fluorescence, spectroscopy and diffraction techniques in an energy scale from 4 to 23 keV. This paper presents a short review of the beamline, including the recent developments towards nano-scale imaging.


We present a robot localization system using biologically-inspired vision. Our system models two exten sively studied human visual capabilities: (1) extracting the "gist" of a scene to produce a coarse localization hypothesis, and (2) refining it by locating salient landmark regions in the scene. Gist is computed here as a holistic statistical signature of the image, yielding abstract scene classification and layout. S aliency is computed as a measure of interest at every image location, efficiently directing the time-consuming landmark identification process towards the most likely candidate locations in the image. The gist and salient landmark features are then further processed using a Monte-Carlo localization algorithm to al low the robot to generate its position. We test the system in thre e different outdoor environments building complex (126x180ft. area, 3794 testing images), vegetation-filled park (270x36 0ft. area, 7196 testing images), and open-field park (450x585ft. area, 8287 testing images) each with its own challenges. The syst em is able to localize, on average, within 6.0, 10.73, and 32.24 ft., respectively, even with multiple kidnapped-robot instances.


kryza Abstract. Prototype designs of orifice flowmeters are commonly used in measurements. One area which has attracted considerable interest includes slotted orifices, where a single central opening is replaced by the use of several slots. This paper reports the results of numerical and experimental research of a prototype design of a slotted orifice plate. The movement of the fluid was described with use of Reynolds equations closed by the k-ε turbulence model. The calculations were performed using ANSYS Fluent software package by consideration of the fluid flow through an orifice plate and slotted orifice with the equal β ratio = 0.5. The results of calculations are compared with the measurements. Good qualitative and quantitative conformity was obtained during the study for the C flow coefficient. It was indicated that the slotted orifice generates a considerable lower pressure drop in comparison to an orifice plate while maintaining comparable level of measurement uncertainty.


Feature films in foreign-language education are a modern, efficient, motivating, stimulating and engaging medium for conveying and experiencing authentic language in real communication situations, for teaching target-oriented, country-specific cultural information as well as for developing intercultural awareness and communication skills. The paper examines the extent to which the use of feature film is actually implemented in L3 German classrooms in Malaysia. Based on two empirical studies conducted via standardized questionnaires and interviews with 43 teachers and 168 learners of German as a Foreign Language, the aim was to examine the importance of film material as a didactic instrument in German language programs and to analyze the motifs and didactic goals for implementing films. Students were interviewed about their media attitudes, their film viewing habits and genre preferences as well as about their perception of aspects of German culture in feature films. Although Malaysian learners of the German language show a great interest in Germany, its people, language, society and culture, teachers – for a variety of reasons but foremost caused by a lack of knowledge about the adequate implementation of feature films – have provided only few "magical moments" in L3 German classrooms thus far.


Blood pressure variability (BPV) following endovascular thrombectomy (EVT) in acute ischemic strokes is associated with poor functional outcomes both in the short and long term. Patient variables which may predict high BPV must be examined to improve outcomes. The purpose of this study is to analyze the affect of BPV on outcomes in patients with good recanalization with EVT and examine potential predictors of BPV.

 We conducted a retrospective analysis of prospectively collected data from an IRB approved Stroke Registry of two academic Comprehensive Stroke Centers in Southern California between 2017 and 2022. Patients were included if they had 1) anterior circulation ischemic stroke due to large vessel occlusions (LVO) and 2) successful EVT with TICI 2b‐3. All BPs were recorded as immediate pre‐op SBP and DBP (one minute prior to procedure start time), immediate post‐op SBP and DBP (at time of recanalization), and 24 hours post revascularization. Variables examined include age, sex, Hispanic ethnicity, initial NIHSS, history of HTN, current antihypertensive use, symptom onset to groin puncture time, door to groin puncture time, and symptomatic ICH (sICH). Outcome was assessed via hospital discharge disposition and modified Rankin Scale at 90 days. Good short‐term outcome was disposition to home or rehab. Good long‐term outcome was mRS of 0–2. BPV was defined by the average real variability (ARV) calculated as the absolute value of the average of the differences between consecutive BP measurements divided by the number of measurements. A correlation matrix was used to identify both continuous and categorical variables with a significant correlation with ARV (p≤0.10). A stepwise logistic regression model for good versus poor outcome was created by including all significant variable from the correlation matrix. A significance level of p≤0.05 was included for all non‐correlational analysis.

 We identified 253 patients (mean age 70±14 years, 51.4% female). 49% were white, 6.3% asian, 5.5% black, 1.6% native Hawaiian pacific islander, and 37.5% are unspecified. 30.4% were Hispanic. The median NIHSS was 17±8. Mean BMI was 27±8. Mean symptom onset to groin puncture time was 478±326 mins. Mean door to groin puncture time was 86±110 mins. 34.8% of patients received tPA (100% of those eligible as our population included patients in the extended window who qualified per DAWN/DEFUSE‐3). 57.2% had cardioembolic etiology. 4.7% had sICH. 58.9% of patients had a good discharge disposition. ARVAB as defined as the average SBP variability as an absolute value was 30.6±25.6. ARVAB was associated with sex, home antihypertensive use, and immediate pre‐op and post‐op SBPs. ARVAB was not associated with age, initial NIHSS, Hispanic ethnicity, HTN, rate of sICH, or short or long term outcome.

 There was a significant correlation with female sex and home use of antihypertensives and higher BPV. These variables can potentially be used as predictors of BPV. BPV was not correlated with discharge disposition or 90 day mRS in our population. While our study did not show a positive correlation between BPV and outcome, our ARVAB was lower than prior populations likely due to more accurate BP monitoring and control.


Based on one traditional Erfle eyepiece,we designed a hybrid refractive-diffractive eyepiece,which is then combined with a suitable Cooke-triplet.The Cooke-triplet,working as relay objective,views the image on a 10-inch-size LCD.So the hybrid refractive-diffractive system for research of visual system's parameters on human factors was achieved,which optical parameters can be adjusted.The maximal lateral color aberration of the hybrid eyepiece drops more than one order in magnitude,the transverse ray fan aberration reduces 70 %,51 % and 34 % in zero,0.707 and maximal fiele of view,respectively,while the total track reduces to 2/3 and the weight reduces to 1/8 compared with the Erfle eyepiece.


ISS Prism, instructing Cecily Cardew to read her Politi cal Economy, added a warning to omit the chapter on the Fall of the Rupee: "It is somewhat too sensational. Even these metallic problems have their melodramatic side." And so they do; but my story will not do it justice. I believe that the story of international money, and of our own balance of pay ments, allows no place for villains and little, even, for fools. To be specific: my contention is that the difficulties which we have faced in international finance have not been the result of American wickedness or irresponsibility or foolishness, or, indeed, of the wickedness of mythical short men in Zurich or mystical tall men in Paris.


Sputtering yields are reported for the release of Mg, Fe, Si and O under impact of He, C, O, Si and Fe on grain material composed of Mg- and Fe-bearing silicates. The yields were derived using the trim code, which simulates the results of the transport of ions in matter by means of classical Monte Carlo techniques. The energetics of the sputtering process are a key factor in the sputtering calculations, and so detailed determinations have been made of the energy with which atoms are bound to the lattice, using solid-state simulation programs. The probability of ejection of an atom is computed at a given energy, for a number of angles of incidence, and integrated to obtain the mean yield at that energy. These numerical results are then fitted with a simple function of energy for convenience in subsequent applications.

A grid of C-type shock models has been computed, using our new sputtering yields, for pre-shock densities in the range 104nHn(H)+2n(H2)106 cm−3 and shock speeds 20vs45 km s−1. Sputtered fractions can be high, exceeding 50 per cent for shock speeds in excess of approximately 40 km s−1. The column densities of Si and SiO were also computed, for comparison with observations.


: This article aims at how "General Chemistry" course should follow up the continuous curriculum reform in high schools, while adapt to the irreversible trend of reducing the course hours in universities. Working towards the solution, we suggest that the course of "General Chemistry" changes the focus from teaching chemistry knowledge to capturing the essence of some scientific ideas and means based on the chemical concepts, principles and conclusions. Such core scientific quality-oriented education, embossing the teaching philosophy of cultivating people as the central task, can be attractive for students with different academic directions.


The pre-publication version of this article is indefinitely embargoed in OpenBU. Please visit the journal website to access the published version of record: https://doi.org/10.1111/rec3.12286


Based on the conditions at Meishan Iron and Steel Co.,the characteristics of CC HCR and CC DR process are systematically analyzed,then the possibility is discussed and a basic concept on technological reconstruction of strip production line at Meishan Iron and Steel Co.is put forward with a purpose to save energy,reduce cost and enhance competitive power.


The basic science in quantum transport of nano-scaled 'devices' is largely based on the availability of suitable model systems. Nanostructures built from conventional metals are typically in the diffusive transport regime. Semiconductors, as the starting material for nanodevices, are different. Because of the low carrier density and therefore reduced screening, the Fermi energy can be tuned by electrostatic gates. Quantum dots which can be filled sequentially with electrons one by one have been realized in this material system (for a review see Kouwenhoven et al (2001 Rep. Prog. Phys. 64 701)). Today, researchers have also started to explore the new possibilities provided by molecules (see, for example, Selzer and Allara (2006 Ann. Rev. Phys. Chem. 57 593), Cuniberti et al (2006 Lecture Notes in Physics vol 680), McCreery (2004 Chem. Mater. 16 4477)). A rather simple prototype 'molecule' is a carbon nanotube (CNT) (for recent reviews, see Anantram and Leonard (2006 Rep. Prog. Phys. 69 507), Dresselhaus et al (2001 Topics in Applied Physics vol 80), Ebbesen (1996 Phys. Today 49 26)). Charge and spin transport in CNTs have attracted a lot of attention in recent years. There are several reasons for this excitement: CNTs are almost ideal quantum-ballistic wires. Large electric field effects have been observed in semiconducting CNTs, potentially of interest for applications in electronics. Because a CNT is an all-surface conductor, the electrical properties are highly sensitive to the environment, which can be exploited in sensing applications. Finally, a wealth of new physics is currently appearing in experiments in which CNT-hybrid devices are used, which employ a combination of normal metal, superconducting and ferromagnetic contacts.


The Karlsruhe Education Model for Industrial Product Development – KaLeP (KarlsruherLehrmodell fürProduktentwicklung) – is a general education concept orientated at the real industrial development process and designed to promote competence in product development. Since 1996 theInstitute for Mechanical Design and Automotive Engineering– University of Karlsruhe (TH) – was developed a new education concept, which was already being used during the training of design engineers in 1998. In particular, the changing working environment of industrial companies today is taken into consideration. The lecture 'Mechanical Design' is the basic component of the KaLeP-Model, which covers the constructive basics. The summer semester of 1999 marked the beginning of this new concept. Right from the start, the lecture was supported by an accompanying workshop, the goal of this workshop is to build up important skills, such as the capacity for teamwork, the ability to comprehend and to organise as well as to develop the student's creativity, skills which are mostly neglected in today's academic education. However, with two additional components – Basics in Product Developmentand Integrated Product Development – based on the lecture mentioned above, high-level training as a design engineer in product development can be achieved. Those components are explained thoroughly in (2).


V S Series Record: Truman leads 49-21-4 First Meeting: 1909 (UMR won 21-0 away) Last Meeting: 2007 (Truman won 38-31 away) Last MST Win: 1983 14-9 in Rolla Last TrumanWin: 2007 Series Notes: The Bulldogs winning streak over MissouriRolla is currently at 22 straight games. Radio: 104.7 FM KRES (12:10 Pre-Game) Announcers: Brad Boyer, Chad Speaker, Hank Janssen, Kevin White WebAudio: Regionalradio.com/KRES Web Video: not available Live Stats: http://gobulldogs.truman.edu SERIES INFORMATION


The article examines Finnish proverbs that include the word herra, or "master," in relation to the social history of the common people. The sample in the analysis consists of 174 proverbs that were collected on the ideological basis of the historic-geographic method where the primary focus was on the evolution of folklore texts. This quantitative emphasis led to the large collections in the Folklore Archives, which now need new methodological choices, such as analyzing the texts as the history of ideas from below.


We present new optical identifications of previously unidentified faint extreme ultraviolet sources. Our total sample of 30 identified sources, of which 22 are new identifications, includes 24 late-type stars, three white dwarfs, two cataclysmic variables (CVs), and one active galactic nucleus. These sources are joint detections of the faint sources from the all-sky surveys of the Extreme Ultraviolet Explorer (EUVE) in the 58–174 Å (0.071–0.214 keV) EUV band and of the ROSAT Position Sensitive Proportional Counter in the 5–120 Å (0.1–2.4 keV) X-ray band. We obtained medium-resolution spectra of the possible optical counterparts with the Shane 3 m telescope at Lick Observatory using the Kast double spectrograph covering a bandpass of 3600–7500 Å. Our sample of active late-type stars is dominated by K and M stars showing strong Balmer and Ca II emission lines. The white dwarfs are fairly typical for those detected in the EUVE survey with Teff and log g ranging from 35 to 53 kK and 7.6 to 8.7, respectively. We found strong H and He emission lines typical of cataclysmic variables (CVs) for EUVE J0854+390 and EUVE J1802+180. EUVE J0854+390 is a newly identified cataclysmic variable showing radial velocity shifts to the red as large as ≈400 km s-1. We associate EUVE J1802+180 with the previously identified CV, V884 Her (RX J1802.1+1804). Including the present work (22 new identifications), EUVE optical identification campaigns have identified ≈28% of the presently cataloged NOID sources.


The characteristcs of relativistic propagation in plasmas of subpicosecond ultraviolet (248-nm) radiation are studied for both spatially homogeneous plasmas and plasma columns. It is established for the first time that the defocusing properties of the interaction can represent a dynamical mechanism stabilizing the mode of propagation against radial oscillations. The dependence of both quasistabilized modes and pulsing waveguide regimes on the initial transverse intensity distribution is examined and, for the latter, the locus of the first focus produced in a homogeneous plasma is calculated.


The desire to establish conditions under which various categories of a product can be accepted emphasizes the need for a realistic measure of each of the number of properties to be specified. In the case of crushed aggregates, the value of these properties will vary continuously throughout the material. It is necessary therefore to estimate what this variation in values is and to establish with what confidence any particular value can be taken as representative of the whole range. The satisfaction of this need requires the use of a statistically based method of quality assurance. Although much of the specification which has been developed is not directly concerned with the statistical basis of the quality assurance process, the whole has been included for the sake of completeness (a).


Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants generated primarily during the incomplete combustion of organic materials. These compounds are contributed to the atmosphere due to various anthropogenic activities in the form of particulate matter. In this study Particulate matter, PM10 samples were collected from a Traffic site (Town hall) and Industrial site (KSPCB) of a coastal city Mangalore in India during post the monsoon period between October to December 2014. The samples were analysed for PAHs namely seven Fluorene (Flu), Acenaphthene (Ace), Chrysene (Chr), Benz(a)anthracene (B(a)A), Benzo(a)pyrene (B(a)P), Benzo(b)fluoranthene (B(b)F), Indeno (1,2,3-c,d) and pyerene (Ind) using fluorescence spectrophotometer. The quarterly average of TPAHs concentration of the industrial site varied from 12 ng/m3 to 109 ng/m3 with an average of about 70.2 ng/m3 whereas TPAHs concentration of traffic site varied from 39 ng/m3 to 252 ng/m3 with an average of 109 ng/m3. Further it was observed that the TPAH concentrations showed increasing trend TPAHoct < TPAHNov < TPAHDec due to meteorological factors. Concurrently TPAH concentrations at traffic site was 1.8 times higher than that of the industrial site. The source apportionment study carried out using Principal Component Analysis (PCA) assisted by varimax rotation revealed that there were only two types of principal components PC1 and PC2. Both the PCs were observed to have variances of 66.21% and 14.38% respectively and classified to originate from fossil fuel burning predominantly diesel/petrol combustion in vehicles for traffic site and the rest from other type of fuels for the industrial site. Article DOI:  https://dx.doi.org/10.20319/mijst.2017.s31.0115 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.


Late preterm infants refer to those born between 34 weeks (34) and less than 37 completed weeks (36). Infants born late preterm may be similar to term infants in appearance, weight, and size, and compared with preterm infants born at earlier gestations, they are generally healthier. However, late preterm infants are developmentally and physically immature compared with term infants. Consequently, they are at increased risk for medical complications such as hypothermia, hypoglycemia, respiratory distress and delayed lung fluid clearance, poor feeding, jaundice, infection, and readmission rates after initial hospital discharge and mortality, especially during the first week after birth. Understanding the morbidity related risks among late preterm infants is not only important for assisting newborn care providers to expect potential morbidity during the birth hospitalization and earlier follow-up after hospital discharge. The present study was done with the aim to evaluate the prevalence of neonatal morbidities and outcomes among late preterm neonates.


The utility model discloses an electric lifting pan-tilt head for a roof camera, which comprises a driving motor (1), a transmission mechanism, a pan-tilt head box (2), a pan-tilt head base (3) and at least two screws (4). The top of the pan-tilt head box (2) is open; the pan-tilt head base (3) is capable of ascending and descending; the four corners of the open surface at the top of the pan-tilt head box (2) are provided with triangular plates (5); at least two opposite angles of the pan-tilt head base (3) are respectively provided with a screw hole (6); each screw perpendicularly penetrates through one screw hole, is connected with the screw hole in a threaded fit manner and supports the pan-tilt head base (3); a first bevel gear (7) is mounted fixedly at the lower end of each screw; the transmission mechanism is respectively connected with each first bevel gear in a matched manner so that each screw is capable of rotating synchronously; the driving motor (1) is connected with one first bevel gear in a meshed manner by the aid of a second bevel gear (8); and the screws drive the pan-tilt head base (3) to ascend and descend after the driving motor (1) drives each screw to rotate. The electric lifting pan-tilt head is capable of realizing electric lifting of the pan-tilt head base within a smaller stroke, and achieving the lifting function of the roof vehicular small camera.


Thin tantalum oxide (Ta 2 O 5 ) films were prepared on Si(100) substrates using the chemical solution deposition (CSD) method. X-ray diffraction (XRD), scanning electron microscopy (SEM), spectrophotometric UV-VIS and ellipsometric measurements were employed to characterize these films. High-quality films of Ta 2 O 5 were obtained by spin coating at 2000, 2250, 2500, 2750 and 3000 rpm during 30 s, and subsequently annealed at 900°C for 15 h. The microstructure and crystallinity of the thin films were analyzed by XRD in preferred (001), (010), (200) orientations, the surface morphology was examined by SEM, and the film thickness was determined by profilometric and ellipsometric measurements, the thin films were heterogeneous. The orthorhombic structure and crystallinity of Ta 2 O 5 thin films on Si(100) substrates were characterized by XRD. The obtained lattice constants are a = 6.117 A, b = 3.716 A, c = 4.114 A. The optical spectrophotometric measurements at λ = 400 nm yielded refractive index values n of 1.81-1.93; from ellipsometric analysis the refractive index values are 1.8-1.94.


Colourfulness typically relates to variation, vividness, kinesthesis, thus life, whereas colourlessness, denoting achromatic or neutral colours, such as black, white and grey, commonly symbolizes monotony, lethargy and lack of life. The presence or absence of colour triggers a certain reaction or state on the part of the viewer, appealing to both their perception and their unconscious self. Such symbolic richness of colours is extensively used in both Romanian and English idiomatic languages, the object of study in the present analysis. The nine series of colourful idiomatic expressions will be examined in turn, paralleled in the two languages and occasionally sentenceillustrated.


Language is one important tool for communication. Language has many variations that used by certain community. Register is one of language variation. Doctor, tailor, other profession or certain community have their own language variation called register. Register is a conventional way of using language that is appropriate in a specific context. In this research, the researcher analyses registers used by NVN konveksi workers and analyze the reason of using registers by NVN konveksi workers.
 The design used in this research is qualitative research design. The subjects of the research are NVN konveksi workers. For collecting the data researcher uses three instruments observation checklist, interview guideline and document.
 The findings show that the NVN konveksi workers use sixty-two of registers. When the NVN konveksi workers work, they use register to communicate each other. There are several work sections in the NVN konveksi: sewing, cutting, printing, embroidery and design section. Each has its registers in every work section. The workers realize that registers are to minimize misleading information for their job and make them faster in transferring the information.


This paper explores the potential of using genetic algorithm to solve the shortest path problem in wireless sensor network. In multihop networks, such as the Internet and the Mobile Ad-hoc Networks, routing is one of the most important issues that has a significant impact on the network's performance. An ideal routing algorithm should strive to find an optimum path for packet transmission within a specified time so as to satisfy the Quality of Service (QoS). There are several search algorithms for the shortest path (SP) problem: the breadth-first search algorithm, the Dijkstra's algorithm and the Bellman–Ford algorithm, to name a few.  Intelligent analysis and designing of network routing provides an edge in this increasingly fast era. The energy efficient genetic algorithm routing prolongs the network lifetime Genetic Algorithm is a problem solving method which is based on the concept of natural selection and genetic. This paper gives an overview of shortest path algorithm with genetic algorithm and  some existing algorithm.


The Second Workshop on New Concepts for Far-Infrared and Submillimeter Space Astronomy aimed to highlight the groundbreaking opportunities available for astronomical investigations in the far-infrared to submillimeter using advanced, space-based telescopes. Held at the University of Maryland on March 7-8, 2002, the Workshop was attended by 130 participants from 50 institutions, and represented scientists and engineers from many countries and with a wide variety of experience. The technical content featured 17 invited talks and 44 contributed posters, complemented by two sixperson panels to address questions of astronomy and technology.


There has been a reorientation in polymer research due not only to the last economic crisis and the stiffening international competition but also to the political debates on the recycling problem. Today we are experiencing a renaissance of the production of classic polymers with new structures, morphologies and supramolecular interactions.


The chromaticity of claret is an important factor influencing claret aesthetic quality. The chromaticity of tinto of the same year was compared with the chromaticity of tinto of different years by spectrophotometer. The results suggested that the chromaticity of tinto was mainly dependant on grape maturity degree, grape age, grape producing area, and late-stage technical management.


The electron effective mass of GaInNAs is important to design excellent long-wavelength lasers on GaAs. However, it remains still unestablished. We find that it is 0.08/spl plusmn/0.1 m0 almost independent of nitrogen content from 0.3 to 1.5%.


Dynamic stability of liquid-filled circular cylindrical shell subjected to supersonic flow and influenced by a moving inside fluid-free surface is investigated simultaneously. Structural modeling is based on the combination of Sanders thin shell theory and the standard finite element method. The shape functions are found from exact solution of shell theory which yields fast and precise convergence. First-order piston theory was applied to derive aerodynamic damping and stiffness matrices coupled with the shell elastic deformation. The fluid inside the shell is modeled as a potential variable at each node of the structure elements and its motion is expressed in terms of nodal degrees of freedom at the interface of the fluid and shell. Effect of axial loading is also investigated by developing a geometrical stiffness matrix. Results showed that ignoring the fluid sloshing effect leads to over-prediction of critical flutter velocities and the most significant deviations are found for short and wide shells with high values of liquid filling ratios. This hybrid numerical-analytical software package can be used effectively for aeroelastic analysis and design of shells of revolution at less computational cost compared to commercial finite element packages.


The Northwest Bioscience Consortium (NWBC) is an NSF funded RCN‐UBE group working to align introductory biology curricula in the Pacific Northwest with the concepts and competencies of Vision and Change. During the last four years, the NWBC has hosted three workshops providing faculty development opportunities for colleagues across the region focused on classroom inclusivity, designing curricula for majors' introductory biology classes, and designing curricula for non‐majors introductory biology courses. We now report on our fourth winter workshop, entitled "A network approach to vertical transfer and articulation for student success in biology." Held February 8–9, 2018, this workshop brought together faculty and administrative participants to collaborate on the NWBC model that all students are transfer students, whether they are transitioning from one institution to another or from introductory courses to advanced courses within the same institution. Day one of the workshop addressed issues affecting faculty, advisors, and administrators working with students in introductory biology courses, including state level initiatives mandating course topic coverage. The second day facilitated faculty groups working on common curricular outcomes to help students be successful in introductory biology courses and in vertical transfer to advanced biology courses. Here we present an overview of our workshop accomplishments and future plans for the NWBC and its RCN‐UBE funding.


This report describes the revised 1990 expanded-cordon transit network, one of a series of simulation networks that have been developed by the Metropolitan Washington Council of Governments Transportation Planning Board (COG/TPB) to represent the regional transit system in the Washington metropolitan area. The networks developed this year have been enhanced to accommodate significant model improvements and to reflect a vastly expanded model area. The modeled area covers about 7,300 square miles (11,745.7 km), including the District of Columbia and twenty other jurisdictions over a three state area (MD, VA, and WV). The area is divided into 1,966 traffic analysis zones and has 47 external stations. The network is comprised of 26,500 links and 16,200 nodes. Transit service offered by Metrorail, Metrobus, other local bus service, commuter bus, and commuter rail is represented in the network. In all, the network comprises 1,040 transit lines. The Metrorail system includes 63 stations, 69 miles (111.02 km) of track, and four lines (Red, Blue, Orange, and Yellow).


An intra-cranial intra-axial foreign body was diagnosed in a golden retriever dog through the use of computed tomography (CT). Confirmed by necropsy, a porcupine quill had migrated to the patient's left cerebral hemisphere, likely through the oval foramen. This case study demonstrates the efficacy of CT in visualizing a quill in the canine brain.


With the aim of developing a DNA sequencing methodology, we theoretically examine the feasibility of using nanoplasmonics to control the translocation of a DNA molecule through a solid-state nanopore and to read off sequence information using surface-enhanced Raman spectroscopy. Using molecular dynamics simulations, we show that high-intensity optical hot spots produced by a metallic nanostructure can arrest DNA translocation through a solid-state nanopore, thus providing a physical knob for controlling the DNA speed. Switching the plasmonic field on and off can displace the DNA molecule in discrete steps, sequentially exposing neighboring fragments of a DNA molecule to the pore as well as to the plasmonic hot spot. Surface-enhanced Raman scattering from the exposed DNA fragments contains information about their nucleotide composition, possibly allowing the identification of the nucleotide sequence of a DNA molecule transported through the hot spot. The principles of plasmonic nanopore sequencing can be extended to detection of DNA modifications and RNA characterization.


In order to get the best geometry of sand castle, in this paper, the energy loss method, iterative method and control variable method are used to analyze the stress of sand castle. Firstly, according to the law of sea water energy loss, the optimal three-dimensional geometric shape of sand castle is a round platform using the iterative method, the results show that the tilt angle of the round platform is 1.203 ~ 1.267 (RAD), and the time of sand castle maintenance is the longest when the sea water depth is 2.6 ~ 3.2cm. secondly, the optimal water to sand mixing ratio of sand castle is 1:12 by using the assignment method. Finally, the influence of rain erosion on the life of sand castle is considered, and some suggestions are put forward according to the analysis results.


The self-healing network is particularly interesting with regard to asynchronous transfer mode (ATM) networks, because the restoration time can be shortened by using the features of ATM networks that permits one to establish backup virtual paths (VPs) with zero bandwidth. This paper studies a new protocol that allows more than one backup VPs to protect single working VP. The number of backup VPs used may be a function of the normal VP's hop length. Results show that this improves considerably the restoration speed of ATM networks from a failure. Two sorts of techniques, named non-overlapped and overlapped backup VPs, are presented. The non-overlapped backup VP based self-healing protocol can recover from all single-link and most node failure scenarios while the overlapped backup VP based algorithm can recover from all link/node failure scenarios. Operation of the protocol is described and the performances are evaluated in term of two criteria, namely the restoration ratio and amount of additional transmission capacity to be employed. Two different meshed network topologies are used to perform the comparative analysis between the new protocol and a better-known end-to-end one.


In the UK, 17,000 people die from injury each year, with uncontrolled bleeding the most significant cause of preventable mortality. Acute Traumatic Coagulopathy (ATC) exacerbates bleeding through the failure of blood-clotting with accelerated clot breakdown that mechanistically is driven by activated Protein C (aPC). No targeted therapy to treat the underlying cause of ATC exists with treatment limited to blood component resuscitation and antifibrinolytic drugs to prevent premature clot breakdown.

 Two hundred fifty-four bleeding trauma patients had Factor V and aPC measured on arrival and during resuscitation. A preclinical ATC model was used to test the novel therapeutic recombinant Factor V (rFV), which is resistant to aPC mediated cleavage. Mice underwent combined injury and pressure controlled-blood loss with intervention at 30-minutes to represent a clinically relevant model. Coagulopathy was measured by ROTEM and biomarkers of coagulation/fibrinolysis.

 Admission levels of FV were 38% lower (83 vs 134u/dL, p<0.0001), deteriorated during resuscitation to 65% of normal after transfusion of eight RBC units and were inversely related to aPC levels. Compared to vehicle, animals treated with rFV had reduced coagulopathy (Clot Strength at 5 minutes: 31 vs 24mm, p<0.01) and significantly improved survival (80% vs 44%, p≤ 0.001).

 FV falls significantly during bleeding in trauma patients and in the murine model, rFV improved coagulation suggesting it may represent a potential therapeutic target for ATC.

 Directly targeting the cause of ATC represents a novel therapeutic strategy in trauma and may improve survival after major haemorrhage by directly improving clot function.