Effects of capillary plasma discharge irradiation at different applied energy on polyethylene terephthalate (PET) polymer films have been investigated by Fourier transform infrared (FTIR) spectroscopy, and ultraviolet-visible (UV-VIS) spectroscopy. Moreover, Irradiation of polymers has become an important technique in producing special materials for electronic applications. Atmospheric pressure non-thermal plasmas are of great interest in polymer surface treatment due to their convenience, effectiveness and low cost. Moreover, irradiation of polymers has become an important technique in producing special materials for electronic applications. Surface of polyethylenetere-phthalate (PET) was modified by plasma produced from the capillary discharge. Some physical properties of PTFE samples were studies. In this paper the change in the surface free energy of (PTFE) samples which is induced by the capillary plasma discharge, is investigated. In addition, FTIR technique is applied for sample analysis, to study the change in the structure of the film as irradiated. The experimental analysis of the film hardness illustrate that the Vickers's micro hardness of the film increases upon plasma treatment. The morphology of the particulate and surface structure which generate by the plasma ablation is investigated. The surface morphology of the pristine and irradiated PET and PTFE samples are investigated as imaged by Scanning Electron Microscope (SEM). Global Scientific Inc.


Single phase rectifier electronics with DC-to-DC converters are commonly used on the low voltage supply network. Such devices (for example Light Emitting Diode (LED) lamps) can pose a threat to Power Line Communications (PLC). Identifying the frequency components in the line current of these lamps can aid PLC designers in mitigating possible interference. This paper analyses a common LED lamp topology and gives the high frequency spectral content of the line current that can cause interference in PLC systems. It is shown that the DC-to-DC converter switching frequency is amplitude modulated by the rectification harmonics around the switching frequency spectrum. Analysis and measurements show how an LED lamp interference frequency signature can be identified.


Introduction Biomechanical models on anterior cruciate ligament deficiency have previously been validated by the use of invasive techniques, measurements under non-weight-bearing conditions, cadavers, and mathematical theory. All these methods have limitations. It has been shown that magnetic resonance imaging (MRI) can accurately quantify knee kinematics. The present study was thus designed to define the relationship between the tibiofemoral contact point and anterior cruciate ligament deficiency in-vivo, using magnetic resonance imaging in weight bearing.


We report on the first demonstration of a novel self starting DC-DC converter to supply power to a wireless sensor node for deployment in high temperature environments. Utilising SiC devices we have realised a novel boost converter topology which is suitable for boosting a low voltage to a level sufficient to power a sensor node at temperatures up to 300°C. This topology is able to self start and so requires no external control circuitry, making it ideal for energy harvesting applications, where the energy supply may be intermittent. Here we demonstrate the potential of this topology to power a direct frequency modulated Colpitts oscillator for RF transmission, when used in conjunction with a thermoelectric generator.


An experimental study of transplantation of first and second set aortic valve allografts in heterotopic infrarenal aortic position in inbred rats with varying histocompatibility is described. On the 20th and 50th postoperative days, there was deposition of donor‐specific antibodies on the allograft endothelia of the weakly allogeneic, non‐MHC group, as evidenced by immunofluorescence studies, whereas the nonviable grafts showed no identifiable antibodies on their endothelia. The endothelia were mostly lost at day 100; previous focal mononuclear cellular infiltrates disappeared. The ground substances, however, were maintained until the 250th day. In the nonviable allografts, the media was completely acellular on the 50th day with collagen disintegration and changes in ground substance on the 100th day. Loss of endothelia and replacement by fibrin deposits with transient focal cellular infiltrations were the most significant early microscopic findings. Acellularity, fibrous neointima, and leaflet thickening due to varying degrees of fibrosis with changes in ground substance and focal infiltrations of macrophages around degenerated collagenous matrix of aortic valve allografts are the significant late changes.


Compared with surveillance video, user-created videos contain more frequent shot changes, which lead to diversified backgrounds and a wide variety of content. The high redundancy among keyframes is a critical issue for the existing summarising methods in dealing with user-created videos. To address the critical issue, we designed a salientarea-sizebased spatial attention model (SAM) on the observation that humans tend to focus on sizable and moving objects in videos. Moreover, the SAM is taken as guidance to refine frame-wise soft selected probability for the bi-directional long short-term memory model. The reinforcement learning framework, trained by the deep deterministic policy gradient algorithm, is adopted to do unsupervised training. Extensive experiments on the SumMe and TVSum datasets demonstrate that our method outperforms the state-of-the-art in terms of F-score.


Starting from some difficulties faced by the library, this paper expounds the characteristics and functions of pastime reading materials, and probes into the measures for the management of pastime reading materials in library.


This article addresses the development of an automated system for reading and analyzing radar readings for discovering biological signals behind it. The idea behind that research is to utilize neural network technologies, and especially convolution neural networks (CNN) to make a process of biological signal analysis automatic and fault-tolerant. It was examined if the CNNs are applicable for such kind of task and their ability to be trained for the prediction of such vital signs. This involves heart-rate from raw radar readings data. To find this out a ResNet50V2 model with custom input and output layers was taken with its weights pre-trained on ImageNET. The model was fine-tuned using the real radar readings data. It was revealed that the CNN model can approximate radargrams to actual heart-rate readings. This research confirmed a guess that CNNs can be a very useful tool for radar reading analysis and prediction of an individual's vital signs according to this data and can be used to build systems based on such predictions.


Subgraph-based graph representation learning (SGRL) has been recently proposed to deal with some fundamental challenges encountered by canonical graph neural networks (GNNs), and has demonstrated advantages in many important data science applications such as link, relation and motif prediction. However, current SGRL approaches suffer from scalability issues since they require extracting subgraphs for each training or test query. Recent solutions that scale up canonical GNNs may not apply to SGRL. Here, we propose a novel framework SUREL for scalable SGRL by co-designing the learning algorithm and its system support. SUREL adopts walk-based decomposition of subgraphs and reuses the walks to form subgraphs, which substantially reduces the redundancy of subgraph extraction and supports parallel computation. Experiments over six homogeneous, heterogeneous and higher-order graphs with millions of nodes and edges demonstrate the effectiveness and scalability of SUREL. In particular, compared to SGRL baselines, SUREL achieves 10X speed-up with comparable or even better prediction performance; while compared to canonical GNNs, SUREL achieves 50% prediction accuracy improvement.


A new six-frame algorithm based on Hariharan' s five-frame algorithmis derived. Although six-frame interferograms are needed, the new algorithm is immune to the effect of reference phase error or the second order detector nonlinearity error.Furthermore, if they exist simultaneously, the new algorithm is insensitive to both of the errors. It is better than B. Zhao and Y. Surrel's six-frame algorithm to some extent.


Objective: To describe a unique case of a different phenotype of ATP1A3 mutation with unique MRI findings. Background: To date, ATP1A3 mutations have been associated with three phenotypes, including alternating hemiplegia of childhood (AHC), rapid onset dystonia-parkinsonism (RDP), and cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss (CAPOS), all of which have normal brain imaging. Here we report a potentially new phenotype in the spectrum of ATP1A3 -related disorders with persistent abnormalities on MRI. Design/Methods: N/A Results: At age 4 years, following an upper respiratory infection the patient presented with gait imbalance, slurred speech and excess fatigue leading to MRI showing bilateral confluent FLAIR hyperintensities along the frontal and parietal lobes, in addition to deep grey matter structure involvement. Due to the unclear presentation, she received IV Solumedrol and after 1 week she returned to near-baseline with mild impairment of her fine motor skills. Follow up imaging after five months revealed persistent, yet no new lesions. Almost one year later, she developed similar symptoms after a febrile illness, leading to a workup including MRI that revealed similar abnormalities with some lesions having restricted diffusion and associated edema. She also developed staring spells with EEG correlation consistent with complex partial seizures. She was treated with IV Solumedrol and Levetiracetam. Subsequently she improved, though she had mild residual speech and language deficits, in adjunct to impairment of her fine motor skills. After an extensive workup, genetic testing identified a de novo pathogenic truncating mutation in ATP1A3 (c.2806C>T), confirming a diagnosis of an ATP1A3 -related disorder. Follow-up imaging 24 months after the first event continues to demonstrate abnormalities. Conclusions: There are three reported phenotypes associated with ATP1A3 mutations, none of which are associated with abnormal imaging. This case demonstrates a potential phenotype in the spectrum of ATP1A3- related disorders, with persistent MRI abnormalities. Disclosure: Dr. Elgallab has nothing to disclose. Dr. Anstett has nothing to disclose. Dr. Lau has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Sanofi/Genzyme, Shire, Pfizer, Actelion. Dr. Krupp has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with as a speaker, consultant and/or participant on an advisory board from Biogen Idec, Novartis, Teva Neurosciences and Multicell; grant support from the National Multiple Sclerosis Society, National Institutes of Health and the Department of Defense. Dr. Krupp has received research support from research support from Novartis, Biogen Idec, Celgene Corporation and Genentech and support from the Lourie Foundation, Slomo and Cindy Silvian Foundation and the Multiple Sclerosis Foundation.


Tyrosinase 1 is a copper-containing enzyme which is widely distributed in nature. This enzyme is associated with the production of melanin for the protection of the skin from solar irradiation. However, overproduction of melanin in the skin is of particular concern to woman, for example, in the conditions melasma and lentigo. 2 Tyrosinase catalyzes the first two steps of melanin biosynthesis, namely the hydroxylation of L-tyrosine to L-dopa and the subsequent oxidation of L-dopa to dopaquinone. Tyrosinase is contained in vegetables and fruits and is responsible for the undesirable enzymatic browning that occurs upon long term storage of these. 3 Therefore, tyrosinase inhibitors have attracted attention as important depigmenting agents for the treatment of hyperpigmentation and as anti-browning agents in vegetables and fruits. Kojic acid 4 (1) is a well known tyrosinase inhibitor. However, its inhibitory activity is not potent enough for the above purposes. To overcome this drawback, many semisynthetic kojic acid derivatives have been synthesized, usually by modification of the C-2 hydroxyl group. 5 Recently, we synthesized kojic acid derivatives containing thioether 6 and ester 7 linkers and evaluated their tyrosinase inhibitory activities. Among them, 2-((cyclohexylthio)methyl)-5-hydroxy-4H-pyran-4-one (2b), showed the most potent inhibitory activity. Compound 2b is composed of three parts, including the kojic acid moiety, a thioether linker, and a hydrophobic cyclohexane group. We synthesized and evaluated additional compounds to get more structural insight into the tyrosinase inhibitory activity of the kojic acid derivatives. The crystallographic structure of tyrosinase has recently been established, enabling closer examination of its three-dimensional structure, which revealed the presence of a hydrophobic protein pocket adjoining the binuclear copper active site. 8 We also conducted a molecular docking study to elucidate the structural importance of the kojic acid derivatives in binding with the active site of tyrosinase. The synthetic pathways of the kojic acid derivatives are shown in Scheme 1. Thioether derivatives (2a-2e) were synthesized by the condensation of kojyl chloride 4 with the potassium salts of thiols. Ester derivatives (3a-3e) were synthesized by the condensation of kojyl chloride 4 with the potassium salts of acids. The inhibitory activities of the kojic acid derivatives on mushroom tyrosinase were investigated using kojic acid as a positive control. The results are summarized in Table 1.


The detail variations of precipitation, potential evapotranspiration (PET) impacts the terrestrial ecosystem.The grassland water deficit or surplus status (GWDS) from 1961 to 2010 were systemically studied for the Qinghai-Tibetan Plateau (QTP) using daily data of all meteorological stations. The results indicated that the temporal variations of precipitation were not corresponding to those of PET in a year. The maximum monthly precipitation occurred in July, while the maximum monthly PET appeared in June, the spring precipitation was ranked the second, but its PET was ranked the first in a year. The total water deficit (PET-precipitation) from March to June was more, 51.4 % of the total annual value. Therefore, the drought more frequently occurred in Spring and June in the QTP. The grassland can be protected in a year, especially in Spring and June.


Fully-suspended tundish car is usually used on square billet caster and it is adopted on 170 mm×880 mm slab caster for the first time after analysis on the structure and production technology of tundish car.The structure of tundish car is designed and the calculation for the driving system is made by this article.It is used on continuous caster of TOSYALI Iron and Steel Company in Turkey in a good operational condition and it resolved the problem in equipment maintenance below tundish car and improved production efficiency.


We introduce a quantity describing the risk preference of the optimal decision problem under random environment, which extends the Arrow-Pratt coefficient of relative risk aversion for the utility function. We show the existence of well-behaved solutions to the evolution equation of the quantity.


Objective To construct the recombinant eukaryotic expression vector pcDNA3.1(-)/hURAT1. MethodsTotal genome DNA was prepared from normal human total blood.DNA was then subjected to PCR amplification.PCR product was cloned into pcDNA3.1(-) and then the recombinant vector transformed into DH5α Ecoli.Constructed pcDNA3.1(-)/hURAT1 was identified by restricting enzyme digestion analysis and DNA sequencing. Results A 1 958 bp fragment,including exon 2 to intron 5 of hURAT1 genome DNA,was obtained by PCR amplification.BamHⅠ and EcoRⅠrestriction enzyme digestion and DNA sequencing confirmed with the correct sequence and direction.The pcDNA3.1(-)/hURAT1 had been successfully constructed. Conclusion The fragment of hURAT1 with correct sequence and direction is cloned into the eukaryotic expression vector pcDNA3.1(-),and it can be applied to gene function research in the future,especially to the mutation function research in the CDS or intron.


54-YEAR-OLD WHITE MAN WAS ADA mitted to the hospital because of Morgagni-Adams-Stokes attacks of ten months duration. As a child, the patient had frequent episodes of epistaxis and pharyngitis. At age 34, he was rejected for military service because of a "heart murmur." The Morgagni-Adams-Stokes episodes increased in frequency and severity, and one week prior to admission, several episodes of syncope with convulsions occurred upon attempting to stand in the upright position. On examination, the patient was pale and apprehensive. His temperature was 9g°F., blood pressure was 160/70 mm. Hg, and the apical pulse, 31 beats per minute. There was moderate distention of cervical veins with large atrial waves occasionally noted. The left ventricular impulse was palpated at the anterior axillary line between the sixth and seventh ribs, and the first apical sound varied in intensity. A grade I1 holosystolic murmur and an intermittent third sound were heard at the apex and along the left *From the Department of Medicine, Vanderbilt Univenity School of Medicine. sternal border. The electrocardiogram COMPLETE HEART BWCK WITH RETROGRADE ATRIAL CONWCTlON


The basic motivation and primary goal of this paper is a qualitative evaluation of the performance of a new weighted statistic for a nonparametric test for stochastic dominance based on two samples, which was introduced in Ledwina and Wyłupek [TEST 21 (2012) 730–756]. For this purpose, we elaborate a useful variant of Kallenberg's notion of intermediate efficiency. This variant is general enough to be applicable to other nonparametric problems. We provide a formal definition of the proposed variant of intermediate efficiency, describe the technical tools used in its calculation, and provide proofs of related asymptotic results. Next, we apply this approach to calculating the intermediate efficiency of the new test with respect to the classical one-sided Kolmogorov–Smirnov test, which is a recognized standard for this problem. It turns out that for a very large class of convergent alternatives the new test is more efficient than the classical one. We also report the results of an extensive simulation study on the powers of the tests considered, which shows that the new variant of intermediate efficiency reflects the exact behavior of the power well.


Russian National Registry of IPF patients was run in 2016 and includes 1027 patients to Feb, 2019. We present baseline characteristics of IPF patients in Russia. Aim: To characterize demographic, clinical, and physiological parameters of IPF patients in Russia. Methods: This was a prospective observational real-life clinical study. Patients were enrolled in the Russian National IPF Registry in 71 regions of Russia. Baseline data included demographic, clinical, functional, radiological and histological data. Results: To the end of 2018, the Russian Registry involved 978 IPF patients; mean age, 64.6±10.8 yrs; 562 males (57.5 %), 374 (38.2 %) were smokers or ex-smokers; 272 (27.8%) had definite IPF. The length of the disease was 19.8±28.4 months. Restrictive ventilation disorders were found in 70.6 % of patients; DLCO decrease Conclusion: The Russian Registry of IPF patients provides useful information on IPF prevalence, demographic and clinical features of IPF course in Russian patients and in physicians' knowledge of diagnosis and treatment of this disease.


Problem of traffic congestion in VANET is an important problem which has drawn the attention of researchers all around the world. This paper proposes a novel position based routing protocol with the idea of baseline and distance minimization using EKF-based content centric approach. The protocol has been implemented successfully for a vehicular ad-hoc network as well as Manhattan model is applied. The vehicularmovement used a new concept of communication using minimization of distance from base line. The base line was drawn from source to destination node. Position, velocity, acceleration and direction are considered. The discussed protocol seems to work quite well and seems to yield encouraging outcomes. The delivery ratio of the packets was increased considerably and the average delay was reduced significantly.


The existence of a new interaction involving the electron neutrino and the nucleons, which has received a convincing confirmation through a good agreement between the theoretical and experimental results concerning all observable processes with solar neutrinos, should also inevitably manifest itself in the deuteron disintegration by the neutral currents of reactor antineutrinos. The special attention is drawn to the problem of finding the neutron registration efficiency, discussed in the preparation of the experiment at the Sudbury Neutrino Observatory and in a number of special studies. Lessons are noted that can be learned from three long-standing experiments on the deuteron disintegration by reactor neutrinos.


Kazakhstan schools, like schools throughout the country, are gradually making the transition to the new content of education. Schools in which Russian is the language of instruction are carrying out this work in accordance with the schedule affirmed by the USSR Ministry of Education. In schools in which Kazakh and Uygur are the languages of instruction, the upper grades, which use textbooks translated from Russian (mathematics, physics, chemistry, biology, history, etc.), are making the transition to the new syllabuses one year later than schools where Russian is the language of instruction (because of the time required to translate the textbooks). The elementary grades in Kazakh and Uygur schools, which are mainly using the textbooks of local authors (except for mathematics) are being converted to the new syllabuses at the same time as the elementary grades of Russian schools. Thus, all 1st grades in the Kazakh and Uygur schools have commenced studying under the new syllabus this year and are using the n...


Automation within spacecraft mission control systems is often limited by the scope of scripting languages or external interfaces provided by the spacecraft control system used. Through a series of studies and prototype developments, SciSys is developing an approach to automation based on an open, layered service architecture, comprising Data Access, Operations Language, Procedure Automation and Schedule Execution layers. The Integrated Common Operations Language (ICOL) offers an implementation of the Operations Language layer, while the APEX product provides automated procedure execution.


Neutral beam injectors are among the most important methods of plasma heating in magnetic confinement fusion devices. The propagation of the negative ions, prior to their conversion into neutrals, is of fundamental importance in determining the properties of the beam, such as its aiming and focusing at long-distances, so as to deposit the beam power in the proper position inside the confined plasma, as well as to avoid interaction with the material surfaces along the beam path. The final design of the ITER Heating Neutral Beam prototype has been completed at Consorzio RFX (Padova, Italy), in the framework of a close collaboration with European, Japanese and Indian fusion research institutes. The physical and technical rationales on which the design is based were essentially driven by numerical modelling of the relevant physical processes, and the same models and codes will be useful to design the DEMO neutral beam injector in the near future. This contribution presents a benchmark study of the codes used for this purpose, by comparing their results against the measures performed in an existing large-power device, hosted at the National Institute for Fusion Science, Japan. In particular, the negative ion formation and acceleration are investigated. A satisfactory agreement was found between codes and experiments, leading to an improved understanding of beam transport dynamics. The interpretation of the discrepancies identified in previous works, possibly related to the non-uniformity of the extracted negative ion current, is also presented.


Leisure boats of today have a lot of electronics that needs battery power to work. In additionto that electric propulsion systems have gotten more popular lately, which further increasesthe demand for high battery capacity. The batteries used are mostly lead-acid batteries and toget the most out of the batteries it is important to treat them right. To optimize the electricsystem it is important to have knowledge of how the batteries and the electric motor are usedand which factors affect e.g. efficiency and recharging.A new electric drive that can replace old diesel engines is being developed and needs testingand evaluation. To efficiently develop the electric drive a monitoring system which reads andlogs important parameters is needed. Furthermore the state of charge of the batteries needsto be monitored and a method for controlling recharging from the propeller created.Electronics to achieve this needs to be created and and its function verified.To create the monitoring system the electric drive was first studied and the parametersneeded for further development, monitoring of the batteries, and controlling of the propellercharging were determined. Thereafter electronics for monitoring the different parameterswere created one by one and then combined to a unit. Basic software to control theelectronics and communicate with a computer was created and lastly the function of all thecomponents was verified.The result is a monitoring system which reads the necessary parameters and present them tothe user on a control panel. Fundamental programming is finished but work is needed onmore advanced software. The unit is capable of logging data with adequate accuracy and sendthe data to a computer over a USB-bus.


Asymmetric Resource Allocation in Relay-Aided Cognitive Radio networks (CRN) is proposed in this paper. Existing schemes on relay-aided CRN are based on Symmetric Resource Allocation (SRA) where the channel states and hence transmission duration is assumed to be symmetric in the secondary Base Station (BS) to Relay Station (RS) and RS to Mobile Station (MS) links. This may not be true for realistic channels and hence our proposed model considers Asymmetric Resource Allocation (ARA) in which the transmission durations are asymmetric. Very little work has been done in ARA for relay-aided networks and none of them consider the CRN environment. The proposed work considers the ARA for Amplify & forward and two-way relaying schemes in CRN. Simulation results show that the proposed ARA scheme increases the system throughput and serves the edge users satisfactorily.


Objectives: In the context of globalization of markets, foreign direct investments have an important role in terms of supporting endogenous growth factors, on the one hand and the circuit of financial flows between countries, on the other hand. If we refer to the effects of the economic crisis on economies, ISD may represent capital infusion instruments for affected economic sectors, contributing to faster recovery of economic gaps that occurred. By studying this topic of FDI we consider the great impact and benefits that they can bring, being essential element in the development of a country, as in the case of Romania. Prior Work: This paper presents the main trends of international financial flows for the period 2008-2012, whereas in the context of economic globalization requires an overall analysis of country-specific FDI performance as it helps in improving and optimizing strategies adopted by foreign transnational companies. Approach: In order to underline their importance and necessity, we study the situation of Romania in this field by analyzing the performance of countries in attracting direct foreign investments. Results: Following the study conducted it has been made a number of conclusions and recommendations on how to improve this process in Romania Implications – Academics, researchers, administrators of the university all have a great responsibility on how they support to attract FDI in Romania, even if we refer to work force that they form, the ideas they can provide in supporting and developing this process or by sharing the "know-how" related to the many fields that FDI can have an impact on. Value This paper aims to bring on the loop the main strengths and weaknesses that Romania has in the field of FDS and invites the readers interested on the topic to involve by providing feedback in order to improve this process in Romania.


We explore a novel approach for Semantic Role Labeling (SRL) by casting it as a sequence-to-sequence process. We employ an attention-based model enriched with a copying mechanism to ensure faithful regeneration of the input sequence, while enabling interleaved generation of argument role labels. We apply this model in a monolingual setting, performing PropBank SRL on English language data. The constrained sequence generation set-up enforced with the copying mechanism allows us to analyze the performance and special properties of the model on manually labeled data and benchmarking against state-of-the-art sequence labeling models. We show that our model is able to solve the SRL argument labeling task on English data, yet further structural decoding constraints will need to be added to make the model truly competitive. Our work represents the first step towards more advanced, generative SRL labeling setups.


Data privacy is of high priority in EU Legal structure. The Digital Rights Management Systems can affect the transfer and management of such data. What are the relative provisions of the Data Protection Directive, the Copyright Directive, the Directive on privacy in electronic Communications along with the European Convention on Human Rights?


The properties of new generation concretes for structural a allow for larger steel percentages, while the increased brittlenessmay be reduced by adding steel fibers in the matrix. Nonetheless, coded procedures for the designof structural members where these new properties are accurately accounted for are still missi ng for a variety of reasons. A recent extension of the Bridged Crack Model allows to evaluate the m echanical behavior of beams in bending where both traditional steel bar reinforcement andfibers are present, accounting for the stresses in the compression zone at the same time. In the m odel, the concrete matrix can be regarded as brittle or quasi-brittle, introducing a cohesi ve law for the fibers-matrix composite. The structure of the numerical method implemented to determ ine the distribution of the cohesive zones and the traction at the steel bars is focused in the pape r, and the variation of the model response with the governing parameters is illustrated. Ste el bars yielding or concrete crushing collapse mechanisms are individuated through appropriate maps.


This master thesis discusses the development of a geographic information system for target energy use monitoring, whose goal it is to follow the use of energy which supervises the consumption and costs in public buildings. The solution should enable a clearer view into the consumption and costs of electric energy in public buildings and public lighting in selected Primorska municipalities, with the option of spatial presentation and spatial analysis. In the beginning of the analytic part of the master thesis, the analysis of energy consumption in public buildings in the areas of Nova Gorica, Brda and Tolmin municipalities was carried out. The research shows which buildings have increased or decreased the consumption of heating energy and the consumption of electrical energy per unit of useful area, based on the index of energy consumption between years 2011 and 2012. In the second part of the thesis, public lighting of the Sempeter-Vrtojba municipality and village Tolmin was analyzed. The results
confirm that the majority of lamps in the Sempeter-Vrtojba municipality and in the village Tolmin are inadequate. The lamps do not correspond either to the Decree on limit values due to light pollution of environment (Official Gazette of RS, No. 81/07) nor to the statutory provision recommendations of engineers about the power and height of lamps and proper installation. With the data of revenues and
investment expenses for public lighting a comparison of the amount of these revenues per person in Sempeter-Vrtojba and Tolmin municipality was made.


A 64-year-old female presented with universal parchmentlike atrophic p laque in extremities and trunk for fi ve years.Hemorrhagic bullae were found in int erior and inferior regions of mammaries and xiphoid process region one mo nth ago .Histopathological examination in n onhemorrhagic region showed typical pathologic findings of lichen scle rosus et atrophicus,while in hemorrhagic region showed formatio n of subepidermal blister in which th ere were lots of erythrocytes.


The effect of a spatially heterogeneous density distribution on the development of defects during the transport of nonwoven webs through roller systems has been investigated numerically. A modeling approach has been developed by which the spatial heterogeneity in web mechanical properties can be characterized statistically and recreated for use in finite element simulations. The approach has been applied to model the transport of a carded nonwoven web, consisting of an agglomeration of polypropylene fibers bound together by a regular array of thermal bond points. The web was scanned optically to obtain a gray scale light distribution representing the local material density. Analysis of the local density distribution permitted the generation of "virtual webs" for use in heterogeneous finite element models, in which local mechanical properties were governed by local density. Virtual web response was investigated under two loading configurations; simple tensile testing, and web transport under tension through a three-roller system. The modeling approach provided results that were in good agreement with experimentally observed web mechanics, failure mechanisms, and processing instabilities. Spatial heterogeneity in material properties was found to strongly influence both general web behavior and the tendency for the web to incur manufacturing defects during transport through roller systems.


The work of Wiles and Taylor–Wiles established the modularity of elliptic curves over the field of rational numbers. (In [7], I had proved that FLT would follow from this modularity.) Their new techniques led to a series of spectacular developments, including Serre's modularity conjecture [9], which was proved in 2009 by Khare and Wintenberger [2,3], and most of the conjecture of Fontaine and Mazur [1]. (For some cases of the proof, see, e.g., [4].) It might be natural to guess that these and other developments in the Langlands program would allow for a vast overhaul of the proof that was completed in 1994. Indeed, there is no shortage of examples of major theorems whose initial proofs were simplified considerably by subsequent analysis. Are we now able to present a proof of Fermat's Last Theorem that is substantially more efficient than the quarter-century old version? Certainly it is possible to formulate what looks like a succinct argument: FLT is a direct consequence of Serre's modularity conjecture [9] (which is now a theorem as mentioned above). Appealing to Serre's conjecture in this way has the technical advantage that the auxiliary (Frey) elliptic curve used in Wiles's argument disappears almost immediately after it is introduced. All we need to say is that if ap + bp = cp (with a, b, and c nonzero integers and p a prime ≥5), then the mod p Galois representation attached to the elliptic curve with equation y2 = x(x − ap)(x + bp) is an irreducible Galois representation that furnishes a counterexample to Serre's conjecture. This one-sentence proof is not a clean simplification of the argument that was presented over a full week at the 1995 Boston University conference. The irreducibility of the Galois representation still relies on Mazur's theorem from [6]. More importantly, the proof of Serre's conjecture uses all of the ingredients that went into the original proof of FLT, plus quite a few more. (In particular, Khare and Wintenberger used Taylor's work on potential modularity [10] to establish Serre's modularity conjecture.) Thus the question remains: is the proof simpler in 2020 than it was in 1995? As one writes on social media, "it's complicated." I will detangle some of the issues in Denver.


The conversion reaction of tritium gas to tritiated water in dry air has been studied using low–concentration tritium gases which have three different hydrogen isotope compositions. The conversion ...


In this study, computer simulations have been performed for the removal of the transformer oil contaminated with polychlorinated biphenyls (PCBs) in supercritical water through complete combustion reaction. We regarded n-decane as a main material of transformer oil, and it is assumed to be 3.0 wt% of transformer oil in supercritical water. We used Peng-Robinson equation of state to estimate the physical properties of components in supercritical water. Throughout the computer simulation done in this work, we could explain the solubilities of 3.0 wt% of transformer oil and excess oxygen in supercritical water.


In this paper, we provide a novel matrix-analytic approach for studying doubly exponential solutions of randomized load balancing models (also known as supermarket models) with Markovian arrival processes (MAPs) and phase-type (PH) service times. We describe the supermarket model as a system of differential vector equations by means of density dependent jump Markov processes, and obtain a closed-form solution with a doubly exponential structure to the fixed point of the system of differential vector equations. Based on this, we show that the fixed point can be decomposed into the product of two factors inflecting arrival information and service information, and further find that the doubly exponential solution to the fixed point is not always unique for more general supermarket models. Furthermore, we analyze the exponential convergence of the current location of the supermarket model to its fixed point, and apply the Kurtz Theorem to study density dependent jump Markov process given in the supermarket model with MAPs and PH service times, which leads to the Lipschitz condition under which the fraction measure of the supermarket model weakly converges the system of differential vector equations. This paper gains a new understanding of how workload probing can help in load balancing jobs with non-Poisson arrivals and non-exponential service times.


A TIR prism system for DMD and a projector adopting the same make a loss of incidence light be reduced, and having a small size and light weight. In a TIR prism system having the DMD and for total reflecting the incidence light to a certain direction in accordance with that the DMD is controlled, the TIR prism system of the present invention includes a first prism for receiving the incidence light on a surface set before, refracting the light, and outputting the refracted light, and a second prism coupled to the first prism for receiving the light outputted from the first prism, transmitting the light to the DMD, and outputting the transmitted light after being totally reflected in accordance with that the DMD is controlled, whereby a loss of light energy inside the system can be reduced.


The vacuum cleaner has water extraction unit with air-liquid separation surfaces between hose inlet and outlet ports preventing infiltration of water to motor. A dry suction device includes an inlet for a hose which is connected to a water extraction device. The water extraction device has a chamber for collecting contaminated water and a liquid detergent chamber. A cleaning head is connected via a hose assembly to the cleaning devices and a detergent tube connects the head to the detergent chamber. The cleaning head is partitioned to separate air and liquid passages and contains a rotating brush within the chamber driven by a small electric motor.


In the 21st century of information systems, the amount of information resources are ever increasing and the role of information searching system is becoming criticalto easily acquire required information from the web. Generally, it requires the user to have enough pre-knowledge and superior capabilities to identify keywords of information to effectively search the web. However, most of the users undertake searching of the information without holding enough pre-knowledge and spend a lot of time associating key words which are related to their required information. Furthermore, many search engines support the keywords searching system but this only provides collection of similar words, and do not provide the user with exact relational search information with the keywords. Therefore this research report proposes a method of offering expanded user relationship search keywords by analyzing user query patterns to provide the user a system, which conveniently support their searching of the information.


Bacoside A, a triterpenoid saponin, is a major constituent isolated from Bacopa monnieri (L.) Wettst. (Scrophulariaceae), used as a memory enhancer. Bacoside A and B are active ingredients in Bacopa herb and have antioxidant and hepatoprotective activities. A new rapid, simple, and economical high-performance thin-layer chromatographic (HPTLC) method was developed and validated for densitometric quantitative analysis of bacoside A in powdered leaves from different geographical regions of India. An amount of 10 mg mL−1 methanol extract of powdered leaves from different geographic regions was used for sample application on precoated silica gel 60 F254 aluminum sheets. Standard bacoside A (1 mg mL−1) was used for calibration curve. HPTLC separation was performed on percolated silica gel aluminum plate 60 F254 (20 cm × 10 cm with 0.2 mm thickness) as a stationary phase using ethyl acetate-methanol-water (4:1:1) as the mobile phase. Quantification was achieved by densitometric analysis at 598 nm over the concentration range of 500–4000 ng band−1. Compact and well-resolved bands for bacoside A from powdered leaves of different geographic regions were found at retardation factor (RF) 0.53 ± 0.02. The linear regression analysis data for calibration curve showed good linear relationship with regression coefficient r2 = 0.9996 and r2 = 0.99810 with respect to peak area and peak height. The method was validated for precision, recovery, and robustness as per the International Conference on Harmonization (ICH) guidelines. Variation in quantitative analysis of bacoside A in powdered leaves sample from different geographic regions was found by HPTLC method. The highest and lowest content of bacoside A in powdered leaves sample from Jammu and Kerala regions, respectively. The variety of B. monnieri in Jammu is superior to other regions of India. The proposed developed HPTLC method can be applied for the quantitative determination of bacoside A in powdered leaves of plant and its formulation.


GLMs with a binomial distribution are designed for the analysis of binomial counts (how many times something occurred relative to the total number of possible times it could have occurred). A logistic link function constrains predictions to be above zero and below the maximum using the S-shaped logistic curve. Overdispersion can be diagnosed and dealt with using a quasi-maximum likelihood extension to GLM analysis.


ABSTRACT To the Editor:— The items in question were not strictly references, in that many of them were not referred to in the contribution. Therefore, "References" was considered, but dropped, since it was an inappropriate term. As Dr. Thompson notes, a bibliography is a list of writings on a subject, each of which, presumably, has been read by the person who names them. Since all of these works were read by the author, the term "Bibliography" was used. The term "Selected" was added to denote the incompleteness of the list. If my memory serves me, The Elements of Style also says, "Be obscure clearly."


Background Vancomycin is associated with disruption of the indigenous microbiota, potentially predisposing patients to overgrowth of endogenous pathogens. Our objective was to determine whether high-dose oral vancomycin is associated with cultures growing gram-negative organisms in adult patients with Clostridioides difficile infection (CDI). Methods This is a retrospective cohort study of 632 adult patients with CDI from January 2015 to December 2017. The primary outcome was prevalence of cultures growing gram-negative organisms within 6 months after onset of the first episode of CDI. A multivariate logistic regression analysis was used to determine predictors of the outcome. Results One hundred fifty-three patients (24.2%) had cultures growing gram-negative organisms after onset of CDI, where urine (97, 63.4%) and blood (27, 17.7%) were the most common sources. The most commonly isolated gram-negative organisms were Escherichia coli (49, 32.0%) and Klebsiella species (34, 22.2%). A total of 38 (38/100, 38.0%) and 48 (48/199, 24.1%) of the patients who received high- and standard-dose oral vancomycin, respectively, had gram-negative organism growth on culture (odds ratio [OR], 2.22, 95% confidence interval [CI], 1.41–3.5; P = 0.02). The multivariate analysis showed that high-dose oral vancomycin (OR, 2.21; 95% CI, 1.29–3.79; P = 0.004) and recent use of antibiotic therapy within 3 months (OR, 2.11; 95% CI, 1.27–3.52; P = 0.004) were associated with positive cultures growing gram-negative organisms. Conclusions High-dose oral vancomycin therapy for CDI was associated with increased risk of gram-negative organisms probably throughout disruption of the indigenous microbiota.


This paper introduces a new home intelligent monitor and information management system based on 8XE, and application of 8XE system by an example. The 8XE system includes such functions as follows: Home Security and Alarm, Home Automation, Remote Measuring Meters(such as gas meter, electricity meter, water meter) and bears the characteristics of practicality, easily operated and technology advanced.


Pound and Bracken's observations on the failure of animal research to translate evidence to humans stem mostly from poor design and conduct of animal research.1

These observations, however, do not apply to zoonotic diseases, which infect multiple species and constitute more than 60% and 75% of …


A new image coding technique for color image based on colorization method is proposed. In colorization based image coding, the encoder selects the colorization coefficients according to the basis made from the luminance channel. Then, in the decoder, the chrominance channels are reconstructed by utilizing the luminance channel and the colorization coefficients sent from the encoder. The main issue in colorization based coding is to extract colorization coefficients well such that the compression rate and the quality of the reconstructed color becomes good enough. In this paper, we use a local regression method to extract the correlated feature between the luminance channel and the chrominance channels. The local regions are obtained by performing an image segmentation on the luminance channel both in the encoder and the decoder. Then, in the decoder, the chrominance values in each local region are reconstructed via a local regression method. The use of the correlated features helps to colorize the image with more details. The experimental results show that the proposed algorithm performs better than JPEG and JPEG2000 in terms of the compression rate and the PSNR value.


The objective of this study was to make a comparison between the characteristics of salmoned trout (Salmo truta) and salmon (Salmo salar) in terms of coloration (CIE L*a*b*), proximate composition, pH and sensory attributes of fresh and smoked fillets in order to obtain a possible alternative for the substitution of imported salmon for Brazilian salmoned trout as a commercial equivalent for retail sales. Results showed that no statistical difference was found for most of the sensory attributes analyzed and for pH. Although the coloration of the fillets presented a statistical difference, the trout presented a more intense coloration than the salmon, proving to be, therefore, convenient to agroindustry.


Objective To evaluate the efficacy of vacuum sealing drainage(VSD) in treating soft tissue defect of extremity in children.Methods Eighteen paediatric patients with post-traumatic soft tissue defects with or without bone or cartilage exposure of extremities were treated with VSD following debridement,and were then treated with dermatoplasty or skin flap grafting after one or two therapy courses,who received VSD treatments after dermatoplasty.Twenty patients with soft tissue defects in control group received traditional dressing.Results Fresh granulation grew well after VSD treatments in 15 cases(5 with bone exposure,3 with cartilage exposure and 4 with tendon exposure).Wound closure was performed by dermatoplasty.Two patients with large-area cartilage exposure and one patient with large-area tendon exposure received skin flap grafting because of poor granulation growth after VSD treatment.All cases recovered.Compared with the control group,the time from injury toⅡ period operation and the hospitalization time were significantly shortened(P 0.01),and the dressing time was significantly reduced(P 0.01),and the healing of skin grafting was significantly elevated(P 0.05),but there was no statistical difference in the complication rate between the two groups(P 0.05).Conclusion The VSD procedure can accelerate granulation tissue growth,reduce operations of skin flap,allay patient's pain and shorten healing time.It's an effective method for treatment of soft tissue defect of extremity in children.But it should be adjusted according to the wound characteristics.Most of the cases with large-area cartilage exposure need skin flap operation besides VSD.


The effect of radio cannot be underestimated. It was perhaps the most important electronic technological innovation of the 20th century, at least in the US. It recone gured notions of public and private, helped usher in a new form of the consumer economy, played a large role in the creation of the star system in the entertainment industry, gave the country the e rst mass-media superstar in popular music, Rudy Vallee, and more. While some scholarly literature (though not much) has paid attention to the programming of music on the air, this essay considers the early days of radio and the rhetoric surrounding the period immediately following its development, and the role that music played in promoting radio. This historical moment in the rise of a technology seems to be a particularly interesting juncture, especially with respect to radio. Workers in the e eld of science and technology studies (STS) tend to concentrate on the development of a new technology, or its subsequent uses, but less attention is given to the way that a technology in development is pushed and cajoled into social existence. It is this long moment that is of interest here. Radio hobbyists proselytized on its behalf in countless articles. Dozens of discussions in the early radio press suggested ways of using the radio— on the beach, in the car, in the boat, camping— so that readers could learn how to integrate the new technology into their everyday lives. Since music was prominently featured on the air in the early days of radio, especially before the rise of the comedy programs, music played an important role in the championing of radio and its early uses.


This entry presents a historical view of the meaning attributed to the terms mechanics and natural philosophy, from a hint to ancient Greece, the Middle Ages, and the Renaissance to a special focus on the 18th Century, which represents a turning point for the development of modern physics and science in general. Since we are not concerned with the summation of the histories of natural philosophy and mechanics, but only with their interrelations, this makes a detailed description of the two disciplines unnecessary.


High physically demanding tasks during daily living activities and industrial tasks are best represented by a with combination of the sagittal and lateral or transverse torque. Based on the results of this study, the combination of sagittal and transverse torque present higher risk of spinal injury compared to pure exertions, all muscles presenting higher activity. The capability and controllability of the generated torques are significantly lowered during combined exertions. These results suggest that the trunk muscles will be taxed at a higher relative load while performing combined loading tasks, increasing the probability of muscle fatigue and low back injury.


READERS OF HIS letters and Prefaces will recall that Henry James ascribed the germinal idea of "The Turn of the Screw" to an anecdote told him by Edward White Benson, a fragment of a tale "dealing . .. with a couple of small children in an out-of-theway place, to whom the spirits of certain 'bad' servants, dead in the employ of the house, were believed to have appeared with the design of 'getting hold' of them."'1 Benson's death two years before the story was written precluded the chance of confirmation, but his sons have questioned the accuracy of the ascription. "My father took a certain interest in psychical matters," wrote A. C. Benson, "but we have never been able to recollect any story which could have provided a hint for so grim a tale."2 E. F. Benson was also present during James's visit to Addington, his father's house, in January, I895, the occasion on which the Archbishop is supposed to have related the anecdote. "But the odd thing," he remarks, "is that to all of us it ["The Turn of the Screw"] was absolutely new, and neither my mother, nor my brother nor I had the faintest recollection of any tale of my father's which resembled it."3 A recent investigator, Robert Lee Wolff, concludes that this testimony makes it "difficult to accept at face value James's account of the genesis of the story."4 Mr. Wolff finds a partial solution to the puzzle in a new source, a picture entitled "The Haunted House," published in the same number of an illustrated London review that contained one of James's earlier ghost stories. After adducing proof that James saw this picture, Mr. Wolff points out striking similarities between the details of the picture and of the story. He


See history unfold in this unique book written and illustrated by an award-winning husband and wife team. The eye-catching fold-out format of "Timelines of Native American History" depicts the richness of Native American culture from prehistoric times to the present day.


Reliable spectrum sensing can be provided with the determination of the presence of licensed or primary user (PU), which is highly necessary for ignoring interruption from secondary bodies or users (SU). Spectrum sensing allocates temporary access of the unused spectral resources of primary (licensed) owners to the secondary (unlicensed) users. As the Cognitive radio environment considers some level of the noise correlation. It is equally essential to have trusted spectrum access methods for low signal to noise ratio (SNR) environments. To model this problem, a Locally Optimum (LO) detection of random signals in presence of correlated noise model for fading channels is used. The performance parameters of LO detection are measured using probabilities of detection and false alarm by performing averages over channel gain h. On analyzing, the simulation results of the LO detection gives better performance than the existing Energy detector.


AbstractThe cost of construction materials has significantly increased in recent years, and construction material suppliers have started to utilize investment derivatives to mitigate risks. While much knowledge has been established on the predictions of using derivatives for risk-hedging, little is known about the evaluation of the risk mitigation by analyzing financial status of construction material suppliers. This paper presents a knowledge-sharing model to determine whether risk mitigation based on the use of derivatives would be beneficial to the companies. This model is developed by first establishing a comprehensive database comprising 560 financial reports on business capacity of construction material suppliers, followed by combining the technique for order preference by similarity to ideal solution (TOPSIS) and k-nearest neighbor (KNN) pattern classification. The benefits of the research described include a knowledge-sharing mechanism in regard to the behaviors of related construction material su...


Solar urticaria is a relatively uncommon photosensitivity dermatosis characterized by pruritic erythema and whealing at sites exposed to sunlight immediately after exposure.1 The phenomenon can also be induced by artificial radiation, and the eliciting spectra vary (UVA, UVB, and/or visible light). Most cases of solar urticaria show erythema and whealing with a short duration, similar to other forms of urticaria. Delayedonset solar urticaria, solar angioedema, and anaphylaxis have been reported as rare cases. Fixed solar urticaria is a unique subtype of solar urticaria. It is characterized by a sunlightinduced immediate skin reaction confined to fixed sunexposed areas. It was first proposed by Leenutaphong in 1990 as solar urticaria induced exclusively in the same localization.2 Thereafter, only seven cases of fixed solar urticaria have been reported, and all have been in adults.3– 7 Here, we describe the first reported case of childhood fixed solar urticaria.


A quick change locator clamp assembly for a plastic molding machine having opposed top and bottom platens adapted to receive, mount and support a sectional die having top and bottom clamp plates which comprises laterally spaced pairs of opposed locator clamp assemblies mounted upon and projecting from the platens. Formed within the clamp plates on one side of the molding die are similarly spaced opposed pairs of locator slots. Each clamp assembly includes a locator key mounted upon a platen of a shape to snugly receive the corresponding clamp plate slot for locating the molding die in a predetermined position relative to the platens. A rotatable clamp is mounted upon the key and adapted for operative retaining engagement with an adjacent clamp plate. The sectional die includes a reciprocal ejector plate, there being at least one reciprocal knock-out bar on the molding machine. A reciprocal lifter plate within the bottom anchor plate is connected to the ejector plate and removably interlocked with the knock-out bar.


1. Basic Requirements for Optimisation. 2. Assessing Plant Performance and Identifying Defects. 3. Water Analysis for Treatment Control. 4. Improving Plants and Their Operation. 5. Determining Design Parameters. 6. Disinfection. 7. Optimising and Upgrading Treatment Plants. 8. Optimisation and Upgrading of a Plant from 100 ls-1 to 250ls-1. 9. Optimisation and Upgrading of a Plant from 1m3s-1 to 2.5m3s-1 10. Optimisation and Upgrading of a Plant from 20 ls-1 to 50 ls-1. Index.


We present BlockRate, a wireless bitrate adaptation algorithm designed for blocks, or large contiguous units of transmitted data, as opposed to small packets. In contrast to state-of-the-art algorithms that can either have the amortization benefits of blocks or high responsiveness to underlying channel conditions of packets, BlockRate has both. Our evaluation shows that BlockRate achieves up to 2.8× goodput improvement in a variety of mobility scenarios.


The poor quality of teaching staff in rural primary and secondary schools has restricted the development of rural education in our country.This article analyzes the measures taken by the government and local authorities to improve the overall quality of these teachers in the following three aspects:improving teachers' treatment and living conditions,innovating on and perfecting rural teachers' replenishment mechanism,and offering diverse training.programs for rural teachers.The purpose of this paper is to provide some salutary lessons for other rural areas so as to develop their construction of teaching staff.


In Today's fast evolving world, number of users of internet is increasing at speed at which light travels. This is directly proportional to requirement of storage. Administering this wide range of data which is commonly called as big data is laborious. Big data is bevy of both structured and unstructured data. Dealing with this big data broach new challenges. Map reduce is the key to tackle these strenuous situations. Map reduce is the most favored evaluating methodology for colossal data processing in disseminated milieu. It is admired and widely accepted because of its outstanding features. Map reduce is hardcore in hadoop. Hadoop is the open source implementation of map reduce framework. It is used for distributed storage and processing of very large data sets on computer clusters built from commodity hardware. Map reduce is combination of map and reduce functions. Mapping and reducing the task based on slot is accomplished to improve momentum. Maps reduce fails to exploit all advantages because of unoptimized resource allocation and utilization. To unravel this we proffer to allow slots to be vigorously awarded to either map or reduce tasks depending on actual need. These designation of slots accomplished break the traditional rules and gave new dimension to overcome the loop holes of slot based methodology. This affects positively and aids to uplift performance of map reduce performance.


BACKGROUND
Cotton is majorly affected cash crops in the present scenario from the attack of many hemipteran pests. Amongst them, cotton mealybug, Phenacoccus solenopsis is devastating and causes tremendous yield loss in the cotton production.

RESULTS
In the present study, 25 potential RNAi target genes were selected from iBeetle database and transcriptome dataset of P. solenopsis. To assess the effectiveness of the selected target genes, three methods were utilized to deliver dsRNA (Ingestion and artificial diet bioassay, and transient gene silencing). Different concentration of dsRNA molecules was fed to insects and mortality was recorded for each target genes. Based on mortality data results, three genes namely, Krüppel homologue-1, ADP-ATP/translocase, and IDGF-1 were selected further for the gene expression studies with reduced concentration of dsRNA (5μg/ml). Amongst the three selected genes for an expression studies, Krüppel homologue-1 showed significant down regulation in their gene expression at two different time-points (8 and 14 days) by 70.81% and 84.33%. Then, RNAi silencing construct was designed for Krüppel homologue-1 under the control of double enhancer CamV35S promoter in the plant binary vector. Significant down regulation in the gene expression by 66.69% and 81.80% was found for Krüppel homologue-1 through transient gene silencing method at the same time-intervals.

CONCLUSION
The present work for the first time provides evidence of targeting Krüppel homologue-1 gene in hemipteran pest, P. solenopsis using RNAi technology through oral delivery and in-plant based transient gene silencing methods. This article is protected by copyright. All rights reserved.


BACKGROUND
Atrial fibrillation (AF) is increasing as the global population ages. Elderly AF patients (≥75 years) have a worse prognosis than younger patients, and effective management is often difficult due to multiple comorbidities. This analysis examined the age-related differences in clinical characteristics and treatment in real-world elderly Japanese AF patients.Methods and Results:The ANAFIE Registry is a multicenter, prospective, observational registry of 32,726 non-valvular AF patients aged ≥75 years. The present study assessed the age-related differences in baseline clinical status and anticoagulant therapy between age groups 75-<80, 80-<85, 85-<90, and ≥90 years. The prevalence of persistent or permanent AF increased, and that of paroxysmal AF decreased, with increasing age (trend P<0.0001). The risk of stroke, based on CHADS2and CHA2DS2-VASc scores, and bleeding, based on HAS-BLED score, increased with age. Both warfarin and apixaban were used more often as age increased (trend P<0.0001, for each), while other anticoagulants were used less. Anticoagulant doses were significantly lower in older patients.

CONCLUSIONS
Permanent/persistent AF, comorbidities, and cardiovascular and bleeding risk all increased significantly with age. Furthermore, use of warfarin and apixaban increased with age, accompanied by a decrease in other oral anticoagulant usage.


Two contrasting views on the pragmatic abilities of blind children are presented. According to the first, many blind children show autistic features, and as a consequence have formulaic speech and pragmatic difficulties. The second view deems that blind children do not show noticeable pragmatic difficulties. This perspective is akin to the functionalist usage-based theory of language acquisition. An example of the type of studies carried out by those defending the autistic-like view is outlined first, and the problems this research raises are commented on.Next, data on the presence of conversational breakdowns, use of pragmatic functions, and pragmatic comprehension abilities coming from my own research are presented. These data indicate that blind children do not show pragmatic difficulties. It is finally concluded that a functionalist perspective is needed to investigate the pragmatic linguistic abilities of blind children.


Nanocelluloses and their different designs, such as films and nanopapers, have gained considerable interest in many application areas due to their unique properties. For many purposes, such as for packaging and electronics, the thermal stability of nanocellulose materials is a crucial characteristic. In this study, the effects of heat treatment (100ºC, 150ºC and 200ºC) on the optical and mechanical properties of 2,2,6,6-tetramethylpiperidinyl-1-oxy radical-oxidised cellulose nanofibre (TO-CNF) films were investigated, especially the alteration of the colour, complex refractive index and birefringence of the films. Exposing TO-CNF films to high temperatures (> 150ºC) induced permanent transformations in the CNF structure, leading to an increase in the refractive index, decreases in the birefringence and crystallinity index, colour darkening and significant deterioration of the mechanical properties.


This paper aims to examine the actual conditions of children's spatial cognition by the hand-worked maps, to make a model lesson plan for developing spatial cognition in Life Environment Studies, and to consider the relevancy of this lesson plan in the actual classroom situation. We got the result that the greater number of the children in the second grade see their space within their familiar surroundings in terms of the route they are involved in. We made the model lesson plan and the thematic unit named "Full of Excitements and Wonders in Our Town". The practice of this unit is considered to have positive effects on children's spatial cognition.


Objectives:  We investigated the antiproliferative effect of Myc down‐regulation via cell proliferation inhibition, cell cycle perturbation and apoptosis in two human astrocytoma models (T98G and ADF) steadily expressing an inducible c‐myc Anti‐sense RNA.


Transient start rolling was an interesting phenomenon commonly occurs in mechanical engineering, but still rarely discussed. Transient, in engineering design, should be considered due to its relation in tangential force, friction, also time and distance. Transient prediction would be very usefull in designing of precisionly engine components and relatively moving apparatus, because the transient periode could has significant effects in material destruction due to velocity differences between two contacting bodies. As a studying example, it's learnt about transient rolling contact conditions with parallel axis cylinder.
The analysis concerned to observe the traction distribution phenomenon, also slip and stick region formation. Transient condition was simulated on model with an applied controlled slip, resulting tangential forces. Analitycally prediction has done with considered literature and two-dimensional modelling using Finite Element. The observation resulted a comparation between analitically results and Finite Element results on parameters rolling distance and traction distribution, with approximately 0.5% in differences.


The soybean (Glycine max L.) is a crop with a high demand for nitrogen (N). The root nodules that form in soybeans can fix atmospheric N effectively. To quantify available N in the soil a field experiment was conducted at Regional Sugarcane and Rice Research Station, Rudrur to evaluate the impact of varying sowing methods and seed rates on yield of soybean and available N in soil after harvest of crop. Planting methods and seed rates significantly influenced seed yield and available nitrogen in the soil. Broad Bed Furrow (BBF) method with seed rate 50 kg ha -1 recorded significantly higher number of pods per plant (105) and mean seed yield of 1891 kg ha -1 over flatbed with 50 kg seed rate ha (1757 kg ha) respectively. Broad Bed and Furrow method of planting recorded a significantly higher live root nodules and available nitrogen in soil with 50 kg seed rate Original Research Article Swapna et al.; IRJPAC, 21(24): 321-327, 2020; Article no.IRJPAC.65586 322 ha. Seed rate of 75 kg/ha recorded highest available N in soil on broad bed and furrow method. Broad Bed Furrow (BBF) method with seed rate 50 kg ha -1 recorded highest net returns ( 53,233 ha) and highest B:C ratio (2.72) over flat bed of planting.


Sainfoin (Onobrychis viciifolia Scop.) is the only species in the genus Onobrychis. Sainfoin is a Eurasian perennial herb that has purple flowers, curved pods and is naturalized in Europe, Asia and North America grasslands on calcareous soil. Sainfoin has been grown in parts of Europe and Asia for hundreds of years. Understanding the relationships among sainfoin ecogeographic, and chemical characteristics may provide insights for better utilizing exotic germplasm. Ten sainfoin populations, were sampled and determined in Serbia and B&H. Some chemical properties, such as crude protein, ash, fat, crude fibre, phosphorus, calcium, magnesium, potassium, K/(Ca+Mg) ratio, and sulfur. Serbia is an important gene origin center for most legume species. Considering the high values of their traits, some Serbian sainfoin populations could serve as a valuable breeding material. In comparison with populations from other parts of the world, Serbian populations are superior in chemical properties and nutritional quality values.


Background and aims Autosomal recessive interleukin-12 receptor β1 (IL-12Rβ1) deficiency is the most common cause of Mendelian susceptibility to mycobacterial disease (MSMD). Here we report a case with multi-drug resistant tuberculosis (MDR-TB) due to mutations of IL12RB1 to investigate the clinical characteristics of MSMD. Methods The clinical features of a child with mutations of IL12RB1 were summarized and the mutations were analyzed by Sanger sequencing. Results The 10-year-old boy was vaccinated with Bacille Calmette-Guérin (BCG) at birth, and suffered BCG disease within 3 months of age. A progressive left side axillary adenopathy was developed, then infections disseminated to the lung, thoracic cavity, peritoneal cavity, intestine, brain, skin, and ear. The patient was diagnosed with MSMD due to IL12RB1 deficiency at five years old. There were no significant abnormalities in routine immunological examinations including lymphocyte subsets, immunoglobulins, complement and neutrophil respiratory burst test. The child didn't receive early and standard anti-tuberculosis therapies after onset, and the disease progressed to MDR-TB. During the whole disease course, the anti-tuberculosis treatments were adjusted several times owing to poor responses. rIFN-γ was added twice a week but stopped because of the adverse reaction of fever. The infections were uncontrolled. Genetic testing revealed the compound heterozygous IL12RB1 mutations c.632G>C in exon 7 and c.1106T>C in exon 10 inherited from farther and mother respectively. Those variations lead to R211P and I369T amino acid changes reported previously. Conclusions Mutations of IL12RB1 can lead to severe MSMD. When there were no obvious abnormalities in routine immunization assessments of patients with BCG disease, the possibility of MSMD needs to be considered. IL12RB1 protein detection and gene analysis are helpful for diagnosis. Standard anti-tuberculosis treatments are conducive to tuberculosis or BCG infection control. The efficacy should be evaluated to determine whether to stop it when adverse reactions of rIFN-γ happen.


We aim to develop a fast, efficient, and automated way to assess the severity of complications after surgeries, so that medical professionals may compare different surgery and treatment options, as well as tailor the treatment plan for individual patients. The Clavien-Dindo (CD) classification is commonly used to categorize post-surgical complications into different grades. We used the data of 494 patients from Raxa, an Electronic Medical Record (EMR) provider in India, to build a model that automatically performs a binary classification of severity with 84% accuracy. We also report preliminary results of predicting the CD grade using this model.


The present communication deals with the principle of measuring and calculating the catalase activity of human blood by UV method. Under the conditions previously described, it has been clarified that the reaction of catalase-hydrogen peroxide practically follows the first order kinetics within 30-120 seconds. The velocity constant, k, seems to have no concern with the substrate concentration within the range of 0.005-0.025 mole. Catalase values, Kcat, measured under room temperature, are about 10% lower than those taken at 37℃. It has been found that measurements of the catalase activity have to be taken within 5 minutes after hemolysis


The process of applying a collection level significance assessment to the entire geological collection at the University of Canberra reveals an interesting and unique collection that reflects past academic endeavors at the former pre-university institution focused on the production of industry ready graduates to feed historic economic booms in Australian mineral exploration. The collection is ungoverned, lacks relevance to contemporary university activity and is at risk. Significance study illuminates characteristics of the collection that could be developed to be of value to the university. We argue that all legacy collections in higher education could benefit from this standard museological process. UNIVERSITY MUSEUMS AND COLLECTIONS JOURNAL 36 — VOLUME 1


Iris recognition is known as an herently reliable technique for human identification. In this paper, a DWT based quality measure for iris images is proposed. It includes preprocessing, feature extraction and recognition. The preprocessing steps such as conversion of color to gray image, histogram equalization and segmentation are carried out to enhance the quality image. The area of interest is selected from which the features are extracted and polar to rectangular conversion is applied. Features are extracted using DWT the templates are generated and match with the stored one using hamming distance and the FAR and FRR is calculated. The algorithm is tested on iris images of UPOL and CASIA. The accuracy of algorithm is found to be equal to 100% while FAR and FRR is equal to 0% as it donot accept the image which is not present in the database (unauthorized person) and donot reject the authorized person. The DWT is consider for recognition process as it is less affected by pupil dilation and illumination along with this it works better in noisy conditions.


A 66-year-old woman presented to our office with a 4-month history of hoarseness that coincided with an upper respiratory infection. She described an inability to project and shortness of breath while speaking. She had been told by her local otolaryngologist that she had a paralyzed vocal fold, and computed tomography of the neck with contrast had been negative. Her history was significant for a sliding hiatal hernia, gastroesophageal reflux disease, and a 30-pack-year history of smoking. On evaluation in our office, the patient's voice sounded slightly breathy, mildly raspy, and high in pitch. Strobovideolaryngoscopy revealed immobility of the left vocal fold with a jostle sign, muscle tension dysphonia, reflux laryngitis, vocal fold bowing with glottic insufficiency, and a left vocal fold pseudocyst—a "paresis podule"1 (figure). Paresis podules are localized areas of Reinke edema that can develop on paretic or paralyzed vocal folds, or on the contralateral vocal fold. These lesions form at the middle of the striking zone as a result of shearing forces and microvascular damage caused by asymmetric closure.1,2 Their presence should prompt an investigation for vocal fold paresis. Because the paresis podule helps close the glottic gap caused by the paresis, it generally should not be removed surgically, especially in the absence of other successful treatment for glottic incompetence. After a comprehensive neurolaryngologic evaluation, initial therapy for a paresis podule should be directed at the vocal fold paresis. Aggressive antireflux measures, when appropriate, and voice therapy should be included. Surgical interventions can be pursued if nonsurgical management fails to improve the dysphonia.


Objective To explore the measures for early diagnosis and treatment of iatrogenic injury in the distal part of common bile duct.Methods The clinical data of 20 patients with iatrogenic injury in the distal part of common bile duct treated in our hospital from 1990 to 2008 were analyzed retrospectively.Results The injuries of 15 cases were found during the operation:11 cases were treated with 3-stoma (bile duct,pancreas,duodenum)+Oddi sphinctreoplasty (OSP),1 case with OSP+choledochojejunostomy,2 cases with the perforated common bile duct suture repair+T tube drainage,1 case with T tube drainage;All of them were cured after surgery.The other 5 cases were not found during the primary operation,2 cases in which were cured with several operations,the other 3 were dead from infectious shock.Conclusions Early diagnosis and treatment of iatrogenic injury in the distal part of common bite duct can obtain perfect effects.Different procedures should be performed according to different degrees of the injury.The perfect preoperative imaging examination and intraoperative choledochoscopy before bile duct exploration may reduce the occurrence of the injury.


CA 19.9antigen ismainlysecreted by biliary and pancreatic ductcelis. Its metabolism couldbemodified ingenetic haemochromatosis byironaccumulation withinthesecelis. Therefore, CA 19.9 wasassayed intheserumsamplesof84 patients withgenetic haemochromatosis beforeand afterirondepletion and immunolocalised in the liverof 24 untreatedgenetichaemochromatosis cases.The studyshowedthatserum CA 19.9(N<37 IU/1)was increased (SD)beforetreatment(41-2(34)) when


Explored power acting on yeast cells Saccharomyces cerevisiae in the field of standing ultrasonic wave by the frequency 2.64 MHz. Shown dependent from concentrations of yeast cells a reduction of power radiation pressures, Stocks and Bjerknes which have values ~4.5×10-10 H, from 1.4×10-9 before 7×10-10-3×10-11 N accordingly


This paper analyses the performance of an absorber tube with a heat transfer enhancer of a solar flat plate collector. The objective is to increase the heat transfer coefficient by increasing effective flow area between the absorbing fluid and the contact surface with increase in minimum pumping power. A novel design procedure is used for solar flat plate collector to reflect the experimental results. Two types of heat transfer enhancers that are rectangular and square are used herein. The heat transfer enhancer is frictionally engaged with the absorber tube and it is kept parallel to the absorbing fluid flow path. The performance factors are analyzed, and the results show that rectangular heat transfer enhancer gives higher efficiency when compared with square heat transfer enhancer with an increase in the convective heat transfer coefficient with minimum increase in pumping power for the heat transfer enhancer.


Pump-probe Kerr spectroscopy reveals evidence for transient photoinduced magnetization (PIM) near Tc in the colossally magnetoresistive manganite La0.7Ca0.3MnO3. For temperatures above Tc, the PIM signature reaches full strength at the field-driven magnetic phase transition, while below Tc it exhibits a magnetic activation threshold of ~0.5 T. We compare the temperature dependence of the effect with diffuse spin scattering previously measured with neutrons and discuss these findings in the context of phase separation near Tc. Comments Copyright American Physical Society. Reprinted from Physical Review B, Volume 71, Issue 7, Article 075117, February 2005, 5 pages. Publisher URL: http://dx.doi.org/10.1103/PhysRevB.71.075117 Author(s) S. A. McGill, R. I. Miller, O. N. Torrens, Alexander Mamchik, I-Wei Chen, and J. M. Kikkawa This journal article is available at ScholarlyCommons: https://repository.upenn.edu/mse_papers/70 Optical evidence for transient photoinduced magnetization in La0.7Ca0.3MnO 3 S. A. McGill,1 R. I. Miller,1 O. N. Torrens, 1 A. Mamchik,2 I-Wei Chen, 2 and J. M. Kikkawa1 1Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA 2Department of Materials Science & Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA sReceived 23 April 2004; revised manuscript received 19 August 2004; published 24 February 2005 d Pump-probe Kerr spectroscopy reveals evidence for transient photoinduced magnetization sPIMd earTc in the colossally magnetoresistive manganite La 0.7Ca0.3MnO3. For temperatures above Tc, the PIM signature reaches full strength at the field-driven magnetic phase transition, while below Tc it exhibits a magnetic activation threshold of,0.5 T. We compare the temperature dependence of the effect with diffuse spin scattering previously measured with neutrons and discuss these findings in the context of phase separation near


A super-hydrophobic polypropolyene(PP) film with a contact angle up to 160°±2° is prepared via the phase separation of polymer/good-solvent/non-solvent.Different kinds of morphologies and hydrophobic properties of the film can be obtained by varying the initial concentration of PP,processing temperature or incorporation of an immiscible polymer elastomer.The mechanism of phase separation is also discussed,which reveals that the different micro-structures are caused by the competition between liquid/liquid phase separation(polymer-rich phase/polymer-poor phase) and solid/liquid(crystallization) phase separation.


After investigating and analyzing the two traditional methods: gray variance and directional image,an approach is introduced to segment the fingerprint images based on the maximum between-cluster variance(MBV),and unit MBV and directional image reasonably,then it presents a new approach namely uses one kind based on the directional image and MBV compound segmentation method.Compared with the two traditional methods,this new method not only has the advantage in the good effect of the segmentation,but also works faster.This method is more suitable for real-time processing.


Spectrum detection technology in cognitive radio includes two processes: channel sensing and channel monitoring. For each process, longer detection time may result in fewer opportunities for cognitive radios to fill in spectrum holes, while shorter sensing time may make cognitive radios miss the chance to detect the presence of primary users which will bring harmful interference to primary users. However, to make sure the detection time has a great relationship with the prior probability of the existence of the primary user in authorized channel, a general and universal authorized channel model is needed for cognitive radios' spectrum detection. In this paper, the duration of primary user's presence and absence is modeled as an exponential distribution, and energy detection method is adopted to detect the channel modeled above. By Monte Carlo simulation, we obtain that the receiver operating characteristic curves for the modeled channel is very similar with the theoretical curve. Therefore, the model is very effective for analyzing the performance of the spectrum detection algorithms in cognitive radio networks.


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The phase space obtained using the isospin quantum molecular dynamical (IQMD) model is analyzed by applying the binding energy cut in the most commonly and widely used secondary cluster recognition algorithm. In addition, for the present study, the energy contribution from momentum-dependent and symmetry potentials is also included during the calculation of total binding energy, which was absent in clusterization algorithms used earlier. The stability of fragments and isospin effects are explored by using the new clusterization algorithm. The findings are summarized as follows: (1) The clusterization algorithm identifies the fragments at quite early time. (2) It is more sensitive for free nucleons and light charged particles compared to intermediate mass fragments, which results in the enhanced (reduced) production of free nucleons (light charged particles, or LCPs). (3) It has affected the yield of isospin-sensitive observables-neutrons (n), protons (p), H-3, He-3, and the single ratio [R(n/p)]-to a greater extent in the mid-rapidity and low kinetic energy region. In conclusion, the inclusion of the binding energy cut in the clusterization algorithm is found to play a crucial role in the study of isospin physics. This study will give another direction for the determination of symmetry energy in heavy-ion collisions at intermediate energies.


The dimensions,weight and configuration of the medium pressure outer cylinder of the 1 000 MW super-super critical steam turbine were introduced.The feasibility of adopting electric arc furnace-ladle refining furnace(LF) duplex melting was analyzed.After adopting measures such as control of the arc furnace-LF duplex melting process,selection of melting charge materials,content control of the carbon,silicon and phosphorus,as well as the control of dross,the ultrasonic test and magnetic test showed that the casting met the requirements of the quality specification,the casting was free of shrinkage and other defect.


This paper surveys practical methods for reservoir modeling. To eliminate unnecessary jargon and to promote synergy, a simple classification system of sand-body architecture is proposed that helps relate geology to fluid flow. Guidelines are given for treating reservoir heterogeneities and upscaling properties to gridblock-scale averages.


The effect of deformation routes on the microstructure, mechanical, and electrochemical properties of low CN Fe-20%Cr alloys by equal channel angular pressing (ECAP) has been investigated in detail focusing on the anisotropy of the microstructure. This alloy is pressed at 423K up to eight passes via the so-called routes A, Bc and C. The continuous refinement of the microstructure is sustained by ECAP until the sub-grain range. However, the degree of anisotropy of microstructural development was different among the three deformation routes. Materials processed by Route Bc exhibited a comparable micro-hardness value in three orthogonal planes than those processed by routes A and C. Pitting corrosion characteristics of the ECAP processed sample were investigated using an electrochemical potentiodynamic test. The increased pitting potential along with an increased number passes of ECAP were explained by enhanced protective passive layer of ultrafine grain structure, as compared to the coarse grain counterpart.


The goal of this paper is to prove an invarianceprinciple for a random field with the dependence property introduced in [1]. This property generalizes the notions of associatedness and negative dependence. Various forms of the invariance principle are known for random fields with the property of associatedness or with properties close to it; see, for example, [2]–[4]. Recall that a function f : Rn → R, n ∈ N is said to be Lipschitz if


Deamination of cytosine to uracil is a hydrolytic reaction that is greatly accelerated at high temperatures. The resulting uracil pairs with adenine during DNA replication, thereby inducing G:C to A:T transitions in the progeny. Interestingly, B‐family DNA polymerases from hyperthermophilic Archaea recognize the presence of uracil in DNA and stall DNA synthesis. To better understand the recognition mechanism, the binding modes of DNA polymerase B1 of Sulfolobus solfataricus (Pol B1) to uracil‐containing DNA were examined by gel mobility shift assays and atomic force microscopy. Although PolB1 per se specifically binds to uracil‐containing single‐stranded DNA, the binding efficiency was substantially enhanced by the initiation of DNA synthesis. Analysis by the atomic force microscopy showed a number of double‐stranded DNA (dsDNA) in the products of DNA synthesis. The generation of ds DNA was significantly inhibited, however, by the presence of template uracil, and intermediates where monomeric forms of Pol B1 appeared to bind to uracil‐containing DNA were observed. These results suggest that Pol B1 more efficiently recognizes uracil in DNA during DNA synthesis rather than during random diffusion in solution, and that single molecules of Pol B1 bind to template uracil and stall DNA synthesis.


Bats use sound to map their environment. They emit sounds and their brains process the received echoes. Using this sense, which is called echolocation, bats succeed at one of the hardest problems in robotics—the need to move in an unfamiliar environment and map it. Many studies have tried explaining how bats do this, and we decided to build the Robat—a robot that navigates the world and builds a map using sound. The Robat has a speaker that produces sounds, and it has two ear-like microphones, to receive echoes. The "brain" of the Robat is a computer that processes the echoes, estimates the locations of objects in the environment, and stores a constantly updated map. The Robat can avoid obstacles and even identify some objects. The Robat moves on the ground using wheels and, in the future, we aspire to make it a tiny, flying, bat-like robot.


It shall be the purpose of the Ohio Society of Pathologist (hereafter referred to as the Society) to offer membership to all reputable doctors of medicine and doctors of osteopathy in the State of Ohio who practice or otherwise are interested in the specialty of pathology; to foster, encourage and sponsor scientific research in pathology; to familiarize other doctors of medicine with the specialty of pathology; to encourage careers in the allied fields of pathology; to make available to all people of Ohio the benefits to be derived from the services of qualifies pathologists; to provide educational programs in the specialty of pathology; to promote the professional interests of its members; and to further the professional and scientific developments of the profession of pathology.


Gabor Szilasi
Born in Budapest in 1928
Pascal Dufour, Isle-aux-Coudres
From the series '' Quebec rural ''
1970, print 2011
27,7 x 35,5 cm


In this paper, we propose a new population-based algorithm (PBA) that adjusts its search mechanism to the problem which is to be optimized. It uses a set of search operators used in commonly-used PBAs and this selection can be made freely. The proposed algorithm selects two operators from this set, i.e. one for exploration and the other for exploitation of the search space of the solution. This approach can be an alternative for finding new inspirations for the development of PBAs and for modifying the existing PBAs. The effectiveness of the proposed algorithm has been tested using typical benchmarks for testing PBAs. An interesting aspect of the performed simulations is the analysis of how operators are used during the optimization process.


Many programming applications, e.g., symbolic and algebraic manipulation applications and artificial intelligence applications, require the use of list structures. Several list processing languages or languages that provide for list processing have been developed, e.g. LISP 1.5, LISP 2, SLIP, PL/1, ALGOL 68, etc. With the exception of ALGOL 68 and LISP 2, none of these languages provide the user with the capability to define the cell size and/or the configuration of the list cell at runtime (PL/1 attempts to do this with BASED structures but falls short because only one component in a BASED structure can have its dimension altered at runtime). ALGOL 68 has the disadvantage that it is not yet readily available for most users, and it suffers from list tracing complexities during garbage collection. LISP 2 was an attempt to allow variable cell configurations, but the project was aborted.


Based on export data of six series of dyed and printed products in 2006,the export situation of dyed and printed fabric was outlined.Many factors affecting exports were analyzed,and their solutions were presented.


ABSTRACT This paper describes the design optimisation study used to aerodynamically optimise the fairings that cover the rear wheels of the Land Speed Record vehicle, BLOODHOUND SuperSonic Car (SSC). Initially, using a Design of Experiments approach, a series of Computational Fluid Dynamics simulations were performed on a set of parametric geometries, with the goal of identifying a fairing geometry that was aerodynamically optimised for the target speed of 1,000 mph. Several aerodynamic properties were considered when deciding what design objectives the fairings would be optimised to achieve; chief amongst these was the minimisation of aerodynamic drag. A parallel, finite-volume Navier–Stokes solver was used on unstructured meshes in order to simulate the complex aerodynamic behaviour of the flow around the vehicle's rear wheel structure, which involved a rotating wheel, and shockwaves generated close to a supersonic rolling ground plane. It was found that the simple response surface fitting approach did not sufficiently capture the complexities of the optimisation objective function across the high-dimensional design space. As a result, a Nelder–Mead optimisation approach was implemented, coupled with Radial Basis Function design space interpolation to find the final optimised fairing design. This paper presents the results of the optimisation study as well as indicating the likely impact this optimisation will have on the ultimate top speed of this unique vehicle.


Terminal moraines and outwash plains associated with Loopline Formation glaciogenic deposits near Kumara in the Taramakau River valley, north Westland, have long been regarded as key morphostratigraphic representations of the early phase of the Otira Glaciation, correlated with Marine Isotope Stage (MIS) 4. Recently published cosmogenic dates and soil stratigraphic studies indicate that moraines and outwash plains in the Loopline type area were formed during the later phase of the Otira Glaciation at c. 25 cal kyr BP, and therefore do not equate with the early Otira Glaciation. Beryllium-10 dating of Balmoral Formation moraines at Lake Pukaki, on the eastern side of the Southern Alps, indicates an age of c. 65 kyr BP, confirming deposition during the early Otira Glaciation and correlation with MIS 4. The Balmoral moraines and proximal outwash plains at Lake Pukaki are therefore proposed as a new reference area for the early Otira Glaciation.


The renewable energy is a promising field, which shows a lot of potential for future energy solutions. The design of the blade shows a lot effects on the efficiency of the wind turbine, and the design parameters governs the performance characteristics. This paper addresses a number of innovative blade designs that was developed by alterations made to the existing conventional straight blade. These blades were extensively studied using computational fluid dynamics (CFD) software, and showed promising results, which was the motive behind this study. We are designing an experiment to study small scale wind turbines, which will enable us to gather data that will explain some differences in power and torque output. These steps will help us to come to a better understanding of some aerodynamic aspects that will impact the performance of each individual blade design. The comparing criteria for this study was the torque generation at the axes of rotation, which can be translated to several parameters, such as energy output, using some theoretical basis equations.Copyright © 2014 by ASME


SUMMARY 4-Hydroxy 3-methoxy mandelic acid (HMMA), and methylated catecholamines, in the urine of eight tetanus patients have been measured by various methods; results have been assessed in the light of the specificity of the methods and possible interference from drug therapy. Although at some stage of their illness, six of the eight cases showed elevated concentrations of catecholamine metabolites, these did not correlate with episodes either of hypertension or of cardiovascular instability, except in a few instances.