The corrosion inhibition on carbon steel in 1MHCl by 1, 2(2, 2-dihydroxy benzelidenamine) phenyl and its complexes was studied at different concentrations by "weight loss method". Data mark, for the compound shows good performance. These measurements show that the inhibition efficiency obtained by these complexes increased by increasing their concentration. The inhibition efficiency follow the order Co>Ni>Cu. The activation and adsorption thermodynamic parameters were determined and discussed. The surface coverage (Ɵ) of the inhibitors conform "Langmuir adsorption isotherm". (Morphology) of the carbon steel alloy has been examine using "scanning electron microscopy" in existence and inexistence of inhibitor.


In Lake Superior there are three principal forms of lake trout (Salvelinus namaycush): lean, siscowet and humper. Wild lean and siscowet differ in the shape and relative size of the head, size of the fins, location and size of the eyes, caudal peduncle shape and lipid content of the musculature. To investigate the basis for these phenotypic differences, lean and siscowet lake trout, derived from gametes of wild populations in Lake Superior, were reared communally under identical environmental conditions for 2.5 years. Fish were analysed for growth, morphometry and lipid content, and differences in liver transcriptomics were investigated using Roche 454 GS‐FLX pyrosequencing. The results demonstrate that key phenotypic differences between wild lean and siscowet lake trout such as condition factor, morphometry and lipid levels, persist in these two forms when reared in the laboratory under identical environmental conditions. This strongly suggests that these differences are genetic and not a result of environmental plasticity. Transcriptomic analysis involving the comparison of hepatic gene frequencies (RNA‐seq) and expression (quantitative reverse transcription–polymerase chain reaction (qPCR)) between the two lake trout forms, indicated two primary gene groups that were differentially expressed; those involving lipid synthesis, metabolism and transport (acyl‐CoA desaturase, acyl‐CoA binding protein, peroxisome proliferator‐activated receptor gamma, and apolipoproteins), and those involved with immunity (complement component C3, proteasome, FK506 binding protein 5 and C1q proteins). The results demonstrate that RNA‐seq can be used to identify differentially expressed genes; however, some discrepancies between RNA‐seq analysis and qPCR indicate that methods for deep sequencing may need to be refined and/or different RNA‐seq platforms utilized.


With the objective of obtaining better performance of beef cattle compared to purebred animals, or those from industrial Taurus-Zebu breeding, a research is being developed in Goias State, Brazil, to study the results of Tabapua and Standard Nelore breeding, product called Tabanel, and the racial characterization of their descendants. The research consists of evaluating the results of three successive generations. The females obtained from Tabapua and Nelore breeding, first generation, will be bred with pure males from both breeds. The generate progeny, second generation, will be breed among themselves, which will generate the third generation. The traditional methods of reproduction, videolaparoscopy to collect oocytes in young females and the in vitro fertilization will be utilized to obtain the descendants. A genetic evaluation of the animals on the three generations will be done by using adequate statistic procedures for the productive and reproductive traits, serial weights, fertility, fitness and precocity, also phenotypic evaluations of conformation, docility, musculature and carcass finishing. The continuation of the research is motivated by obtaining animals with adequate weights for ages and proper phenotypic characteristics observed in pilot study, without any special food or medical supplements. Four hundred cows involved in this work were registered on the Brazilian Association of Zebu Breeders (ABCZ).


Securities and Exchange Commission (SEC) provides oversight to RIAs managing at least $100 million of Regulatory Assets under Management (RAUM). The number of Registered Investment Advisors (RIAs) managing these assets has increased significantly. In addition, there is increased public pressure to provide broader oversight resulting from regulatory failure of RIAs and Investment Advisor Representatives (IARs). The SEC and organizations such as the Investment Advisor Association (IAA) are lobbying Congress for more resources to provide adequate oversight. Even the smaller firms (managing less than 3.6% of RAUM) are held to the same level of oversight, expense and reporting requirements as the large, very complex investment advisors who manage 96.4% of the assets. This paper identifies and explores five key areas the SEC has marked as the most probable areas of failure, affecting the markets and consumers. It is questionable whether these major concerns highlighted in SEC releases, no-action letters and speeches are relevant to the smaller firms who do not take custody or provide true discretionary management of assets. The level of reporting and scrutiny placed on smaller RIAs using a simple business model, is likely, a waste of SEC resources and taxpayer money. If the SEC delegated oversight of these less complicated RIAs to trained, licensed and regulated compliance consultants, the SEC would reduce their regulatory workload and could refocus resources on larger firms, susceptible to conflicts of interest and other compliance violations established in the 1940's Act. This small change would actually enhance regulation of smaller firms, and would bring meaningful relief to them at the same time. The advantages are significant. This change would allow smaller firms to provide a higher level of service and build better relationships with their clients.


A new monoclinic ( Cc ) polytype, mckelveyite-(Y)-2 M , NaBa 3 CaY(CO 3 ) 6 ·3H 2 O, was found in "Cava Fabi", a talc quarry near Lanzada in Val Malenco, Lombardy, Italy, associated with anatase, brookite, brucite, calcite, dolomite, ilmenite, lindsleyite, magnesite, magnetite, pyrite, quartz, redledgeite and rutile, in hydrothermal carbonate veins intercalated in ultrabasic rocks and dolomitic marble in contact with serpentinites. The origin of the mineral is related to circulation of CO 2 -rich fluids in serpentinites, during the latest stages of Alpine metamorphism. The monoclinic mineral, space group Cc , has cell parameters a 15.8213(7), b 9.1364(4), c 13.7522(6) A, β 112.44(1)°, V 1837.35(15) A 3 , with marked pseudorhombohedral symmetry. The crystals are pseudopyramidal, up to 4 mm in length, with distinct trigonal character derived from intergrowth of three individuals twinned about a pseudo-threefold axis, in some cases showing re-entrant angles. The chemical analysis obtained by wavelengthdispersion electron-microprobe analysis, supplemented by structural data for CO 2 and H 2 O, gave (wt%): Na 2 O 3.50, CaO 5.68, SrO 3.45, BaO 45.33, Y 2 O 3 8.82, Sm 2 O 3 0.05, Gd 2 O 3 0.45, Dy 2 O 3 1.10, Er 2 O 3 0.85, Yb 2 O 3 0.08, CO 2 27.13, H 2 O 5.55, total 101.99, corresponding to the empirical formula (calculated on the basis of six metal sites in the asymmetric unit, as shown in the structure solution): Na 1.00 (Ca 0.83 Na 0.07 Sr 0.11 ) ∑1.01 (Ba 2.79 Sr 0.20 ) ∑2.99 (Y 0.74 REE 0.13 Ca 0.12 ) ∑0.99 [CO 3 ] 6 ·3H 2 O. The crystal structure has been refined to a final R = 0.0283 for 4454 observed reflections [ I > 2σ( I )], and corresponds to the first accurate determination of the structure of mckelveyite-(Y). The unit cell contains three independent atomic sites occupied by Ba plus minor Sr, and three sites occupied almost exclusively by Na + , Ca 2+ , and Y 3+ (plus the REE), respectively; there are alternate double layers of pseudohexagonal rings perpendicular to the c* axis containing either the Ba atoms or the other metal atoms, with no substantial disorder; each double layer is the mirror image on {010} of the adjacent ones. The strongest six lines in the X-ray powder-diffraction pattern [ d obs in A( I ) hkl ] are: 3.106(100)(312), 4.299(48)(310), 6.369(36)(002), 2.029(29)(602), 3.180(28)(004), 2.635(27)(602). The pattern shows significant differences with respect to type triclinic mckelveyite-(Y).


In this paper, an approach for the implementation of a quality-based Web search engine is proposed. Quality retrieval is introduced and an overview on previous efforts to implement such a service is given. Machine learning approaches are identified as the most promising methods to determine the quality of Web pages. Features for the most appropriate characterization of Web pages are determined. A quality model is developed based on human judgments. This model is integrated into a meta search engine which assesses the quality of all results at run time. The evaluation results show that quality based ranking does lead to better results concerning the perceived quality of Web pages presented in the result set. The quality models are exploited to identify potentially important features and characteristics for the quality of Web pages.


CLIMATE RESEARCHA committee of the National Research Council last week called for substantial revisions in the Bush Administration's draft plan for climate research, declaring that the "draft plan lacks most of the basic elements of a strategic plan ... neither an explicitly stated vision nor a coherent set of goals are consistently presented."


The aim of this paper is to estimate the different channels of the so-called self-productivity feature in the dynamic process of skill formation and thus to contribute to a better understanding of the technology of skill production in childhood. First, we present a model of skill formation including different channels of self-productivity, one of them being dynamic complementarity. Second, based on data of a broad battery of primary school students' skills and an exogenous variation of one of these skills, we estimate self-productivity and the implications for skill profiles. We discuss the implications for the intergenerational transmission of skills and SES and for policy recommendations. ∗University of Mainz, firstname.lastname@example.com, email@example.com


This paper describes an analysis and design of a self-acting grooved-journal air bearing and a hybrid thrust bearing with a permanent magnet and an air chamber with an orifice used for a polygonal scanner which has been applied to high-speed laser-beam copy machines for commercial use. The operating speed of the scanner rotor is 21700 rpm. The grooved-journal air bearing is optimally designed to meet the conflicting requirements of imbalance vibration suppresion and whirl stability. A magnetic thrust bearing, which is composed of a pair of permanent repulsive magnets on both upper and lower sides, is designed theoretically. Additional stiffness and damping are applied by an air chamber with an orifice whose characteristics are designed by analytical and empirical methods.


INTRODUCTION: polymerization shrinkage of composite resins causes stresses that may exceed the strength of the bond with the surrounding tooth structure, leading to interfacial failure. The use of an adhesive system is always required. OBJECTIVE: The purpose of this in vitro study was to compare the effect of total-etch adhesive system with self-etch adhesive system on microleakage of universal nano-hybrid composite resin when used to restore class V cavities in primary teeth. MATERIALS AND METHODS: The sample consisted of 50 freshly extracted sound primary teeth. Standardized class V cavity preparations on the buccal surfaces were prepared and the sample was randomly divided into 2 equal groups: Group I: 25 teeth received total etch adhesive system. Group II: 25 teeth received self-etch adhesive system. The cavities were restored with a universal nano-hybrid restorative material. All specimens were thermocycled and immersed in 0.5% basic fuchsine dye at 37C˚ for 24 hours. Basic fuchsine penetration was assessed on a 4 point grading scale (0 to 4) using a stereomicroscope to evaluate the microleakage of the restorations. RESULTS: Comparing the percentage of microleakage scores of group I and group II at occlusal margin it was found that, the group I was significantly lower than group II (p=0.041). As for percentage of microleakage scores for the gingival margin between groups I and II it was found that there was no significant difference (p=0.741). Comparing the percentage of microleakage scores at both the gingival and occlusal margis of group I and II, no significant difference was revealed (p=0.105) (p=0.278) respectively. The sum of occlusal and gingival percentage of microleakage scores of group I compared to group II revealed no significant difference (p=0.325).. CONCLUSION: There is no significant difference in microleakage sum scores between total etch and self-etch adhesive system groups. At the occlusal margin, total-etch adhesive system was significantly better than the self-etch adhesive systems. KEYWORDS: microleakage, total etch adhesive, self- etch adhesive, primary teeth.


This case report describes a woman aged 56 years who presented with decreased visual acuity in the right eye and peripapillary/perivenous changes on retinal examination.


Abstract A comparison is made between seven different numerical methods for calculating two-dimensional thermal convection in an infinite Prandtl number fluid. Among the seven methods are finite difference and finite element techniques that have been used to model thermal convection in the Earth's mantle. We evaluate the performance of each method using a suite of four benchmark problems, ranging from steady-state convection to intrinsically time-dependent convection with recurring thermal boundary layer instabilities. These results can be used to determine the accuracy of other computational methods, and to assist in the development of new ones.


Purpose of reviewNew evidence for recommendations for vitamin D supplementation in healthy infants based upon recent literature. Recent findingsRandomized controlled trials published since 2009 that related to vitamin D doses in infancy were reviewed. They do not provide any additional evidence that larger, more generous amounts of daily vitamin D beyond the customary recommended 400 IU daily dose, affect any significant outcome. Larger amounts may lead to serum 25 hydroxy vitamin D concentrations that have been reported to be potentially associated with adverse effects. SummaryThere are still many unanswered questions left, in particular whether or not more 'generous' amounts of vitamin D in infancy may improve long-term health outcomes such as prevention of osteoporosis, allergies, or cancer.


Despite increasing professional awareness and a rising global consumption of morphine, cancer pain remains poorly managed. Even in developed countries, 40% of patients receive inadequate analgesia given the severity of their pain. The problem appears to be greater in ethnie minorities, when the physician's assessment of pain is most at variance with that of the patients, in patients with a good performance status, in the elderly and in women. Reasons for inadequate pain management include poor or incomplete assessment, inadequate titration of analgesia leading to under-dosing, no pre-eruptive adverse effect management, inadequate followup and insufficient use of adjuvant analgesies. In specialist palliative care, half of ali patients rate their pain as moderate or severe. Multiple pains are common, as are the mechanisms that cause the pain. Episodic pain, encompassing breakthrough pain, end-of-dose failure pain and incident pain, are also common, occurring in 23-90% of patients, on average seven times a day. lt is often severe or excruciating, sudden in onset, unpredictable and rapidly reaches its peak. Average duration varies between 30 and 60 minutes. The ideal analgesie for episodic cancer pain should be a strong opioid with a rapid on set of effect, weil tolerated and convenient to administer.


Acute kidney injury (AKI) and chronic kidney diseases (CKD) are associated with high mortality and morbidity in hospitalized patients. Although the underlying mechanisms determining the transition from acute to irreversible chronic injury are not well understood, immune mediated inflammatory processes are critical in renal injury. We have performed a comparison of two mouse models leading to either kidney regeneration or fibrosis, to better characterize the cellular and molecular events leading to both outcomes. Global gene expression profiling and histological analysis revealed a major upregulation of immune system related pathways during fibrosis. Further unbiased examination of the immune cell composition, using single-cell RNA sequencing, revealed that tissue resident macrophages and T cells were major altered populations. In fibrotic kidneys, there was a marked increase in tissue resident IL33R+ and IL2Ra+ regulatory T cells (Tregs). Indeed, prophylactic expansion of this population resulted in protection from kidney injury and fibrosis. Transcriptional profiling of Tregs showed a differential up-regulation of regenerative and pro-angiogenic set of genes in the regeneration model, whereas they expressed markers of hyper activation and fibrosis in the fibrosis model. This suggests that Tregs could exert different functions in the same tissue, dictated by environmental cues. Overall, we have provided a detailed cellular and molecular characterization of murine kidneys after injury and identified key changes in immune cell populations during fibrosis development.


Since its launch in 2008, sugammadex has been considered one of the most significant developments in anaesthesia-related pharmacology. With almost 500 sugammadex-related publications and over nine million patient exposures worldwide, user experience and scientific data have grown exponentially. However, several important questions are yet to be answered. This article reviews the sugammadex-related literature in 2013 and 2014 to determine which of these questions have been answered more fully over the last 18 months and which questions require more information and research.


Phosphorus is a major limiting nutrient in soils in Ghana. Selection of cowpea varieties that produce good seed yield under low soil phosphorus or those with high phosphorus response efficiency can be a low input approach in solving this problem in Ghana. Two seasons experiments were conducted to evaluate influence of phosphorus (P) fertilizer on growth, nodulation and yield in cowpea. The experiment comprised 12 treatment combinations of 3 cowpea varieties and 4 levels of triple super phosphate (46% P 2 O 5 ) laid out as a factorial in RCBD with four replications. The cowpea varieties were Asetenapa (IT81D-1951), Asomdwee (IT94K-410-2) and IT89KD-347-57 and levels of P were 0, 20, 40 and 60 kg ha G 1 P 2 O 5 . In the present study, Asomdwee and IT89KD-347-57 recorded the highest and lowest crop growth of 7.88 and 2.02 g m G 2 day G 1 at 45 and 60 days after planting, respectively. Growth rate was not consistent with P application; however, application rate of 60 kg ha G 1 P 2 O 5 yielded the least growth rate in the entire study period except for 60 days after planting in the minor season. Statistically, Asetenapa and Asomdwee recorded similar number, effectiveness and dry weight of nodules and were significantly different from that of IT89KD-347-57 in both seasons. Number, effectiveness and dry weight of nodules in all varieties were directly proportional to rates of P fertilizer application in both seasons. Asomdwee produced the highest seed yield of 1557.00 and 1415.00 kg ha G 1 for major and minor seasons, respectively. The rate of P fertilizer application was directly proportional to the seed yield in all three cowpea varieties. The highest seed yield of 1682.00 and 1476.00 kg ha G 1 for major and minor seasons, respectively was produced at 60 kg ha G 1 P 2 O 5 application. Farmers are, therefore, encouraged to use P fertilizer in cowpea production in Ghana.


A population panel of 192 rice genotypes comprising traditional landraces and exotic genotypes from 12 countries was evaluated for 12 agro - morphological traits by principal component analysis for determining the pattern of genetic diversity and relationship among individuals. Twelve quantitative characters i.e. plant height, leaf length, number of productive tillers, panicle length, number of filled grains, spikelet fertility, days to 50% flowering; days to harvest maturity, grain length, grain width, grain length width ratio, and single plant yield were measured. The largest variation was observed for number of productive tillers with Coefficient of Variation (CV) of 28.03% followed by number of filled grains per panicle, single plant yield, leaf length , grain length width ratio. Days to maturity has shown the least variation with the CV of 9.74%. Principal component analysis was utilized to examine the variation and to estimate the relative contribution of various traits for total variability. In the current study, Component 1 had the contribution from the traits such as days to 50% flowering, leaf length, plant height, panicle length, days to maturity and number of filled grains which accounted 28.46% of the total variability. Grain width and grain length width ratio has contributed 16.8% of total variability in component 2. The remaining variability of 14.4%, 11.7% and 9.3% was consolidated in component 3, component 4 and component 5 by various traits such as spikelet fertility, single plant yield, grain length and number of productive tillers. The cumulative variance of 80.56% of total variation among 12 characters was explained by the first five axes. Thus the results of principal component analysis used in the study have revealed the high level of genetic variation and the traits contributing for the variation was identified. Hence this population panel can be utilized for trait improvement in breeding programs for the traits contributing for major variation.


Hybrid Propulsion is an attractive alternative to conventional liquid and solid rocket motors. This is an active area of research and technological developments. Potential wide application of Hybrid Engines opens the possibility for safer and more flexible space vehicle launching and manoeuvring. The present paper discusses fundamental combustion issues related to further development of Hybrid Rockets. The emphasis is made on the two aspects: (1) properties of potential polymeric fuels, and their modification, and (2) implementation of comprehensive CFD models for combustion in Hybrid Engines. Fundamentals of polymeric fuel combustion are discussed. Further, steps necessary to accurately describe their burning behaviour by means of CFD models are investigated. Final part of the paper presents results of preliminary CFD simulations of fuel burning process in Hybrid Engine using a simplified set-up.


Preface. Acknowledgements. 1: Biotechnology In Modern Times. 1. The concept of modernity. 2. The concept of biotechnology. 2.1. Definitions. 2.2. Applications. 2: Council Of Europe Policies On Biotechnology. 1. The Parliamentary Assembly. 1.1. The beginnings. 1.2. Developments of doubt and difficulty. 1.3. A new convention as a solution. 1.4. Recent initiatives. 1.5. Results. 2. The Committee of Ministers. 2.1. Systematic beginnings. 2.2. The struggle for standards. 2.3. Results. 3. Council of Europe Conventions. 3.1. The European Convention on Human Rights. 3.2. The European Social Charter. 3.3. The European Convention on Human Rights and Biomedicine. 3.4. The Protocol on Human Cloning. 3.5. The Protocol on Transplantation. 4. Conclusion. 3: Biotechnology And Human Agency. 1. The human act. 2. Technique and technology. 3. Modern concepts of agency and identity. 4. Is 'biotechnology' merely a name. 4: Biotechnology Beyond Modernity. 1. A postmodern sketch of the human self. 2. Technology as bluff. 2.1. Human mastery. 2.2. The ambivalence of new techniques. 2.3. The dominating role of technology. 2.4. Conclusion. 3. The politics of contemporary biotechnology. Appendix. European Convention on Human Rights and Biomedicine ETS 164 (Full text) with list of declarations. Additional Protocol to the Convention on Human Rights and Biomedicine on the Prohibition of CloningHuman Beings ETS 168 (Full text) with list of declarations. Additional Protocol to the Convention on Human Rights and Biomedicine on Transplantation of Organs and Tissues of Human Origin. ETS 186. (Full text). References. Index.


Asiatic black bears (Ursus thibetanus thibetanus) are considered vulnerable throughout their range. In 2012 we conducted field surveys and questionnaires in the autonomous state of Azad Jammu and Kashmir in Pakistan to document the presence of bears and to evaluate human – bear conflicts. We recorded bears mainly in the northern and eastern part of the study area and documented wide-scale human – bear conflicts, which often resulted in the killing and a generally negative public perception of bears. We recommend additional studies to more accurately evaluate black bear status, biology and human – bear conflicts and the establishment of a protected area for bears in the region. On a national level, an Asiatic Black Bear Action Plan that will guide and coordinate research, management and conservation efforts is necessary to safeguard the future of the species in the country.


the Netherlands. Based on the Advocacy Coalition Framework, we first show how the Paris Agreement on global warming in 2015 has led to a new renewable energy policy paradigm, in which digitalization plays a key enabling role. We will then show that the far-reaching convergence of electricity and digitalization pursued by European and Dutch policy makers will raise new policy issues. The core challenge is adequate energy data governance. Digitalization also raises policy issues in the areas of safety, consumer protection, democratic control, and equal distribution of costs and benefits in a digitized energy system. As the transition to a sustainable energy system must take place rapidly and energy data are expected to play a crucial role in achieving this, these issues are urgent.


The most recent video coding standard, High Efficiency Video Coding (HEVC), is able to significantly improve the compression performance at the expense of a huge computational complexity increase with respect to its predecessor, H.264/AVC. Parallel versions of the HEVC encoder may help to reduce the overall encoding time in order to make it more suitable for practical applications. In this work, we study two parallelization strategies. One of them follows a coarse-grain approach, where parallelization is based on frames, and the other one follows a fine-grain approach, where parallelization is performed at subpicture level. Two different frame-based approaches have been developed. The first one only uses MPI and the second one is a hybrid MPI/OpenMP algorithm. An exhaustive experimental test was carried out to study the performance of both approaches in order to find out the best setup in terms of parallel efficiency and coding performance. Both frame-based and subpicture-based approaches are compared under the same hardware platform. Although subpicture-based schemes provide an excellent performance with high-resolution video sequences, scalability is limited by resolution, and the coding performance worsens by increasing the number of processes. Conversely, the proposed frame-based approaches provide the best results with respect to both parallel performance (increasing scalability) and coding performance (not degrading the rate/distortion behavior).


Security is an important issue nowadays in almost every network. Security and energy efficiency are critical concerns in wireless sensor network (WSN) design. Although various Media Access Control (MAC) protocols have been proposed to save the power and extend the lifetime of WSNs, the existing designs of MAC protocol are insufficient to protect the WSNs from Denial-of-Sleep attacks in MAC layer. Denial of sleep attacks are a great threat to lifetime of sensor networks as it prevents the nodes from going into sleep mode. In this paper we are describing prevention against Denials of sleep attack. We have analyzed each of proposed solutions, identify their strengths and limitations.


pressure varied from 170 to 40 mms. Nor-adrenaline was given. The patient died 12 hours after operation. Post-mortem examination: metastasis the size of a tennis ball in the posterior third of the left cerebral hemisphere. Histology: adeno-carcinoma compatible with a primary tumour of the breast. No other metastases were found. Cause of death: cerebral compression by metastasis.


Moulds grow when humidity is high. About 100,000 species ofmoulds are known, but only some of these are toxigenic and produce deleterious secondary metabolites. These are known as mycotoxins and develop when the environmental conditions, such as moisture, temperature, and nutrients, are conducive to the growth of moulds and to the production of specific mycotoxins. Stored grain and other agricultural products are usually contaminated by a variety of microorganisms and by their secondary metabolites. The effects of consumption of such food will depend on the types and the levels of the respective mycotoxins present in the mixture [I]. There is little doubt that, from the remotest past to the present day, mycotoxins have been the cause of various disorders of animals and man, but their relationships have seldom been recognised. Because of the scientific studies of mycotoxins during the past 20 years, it is now possible to attempt an interpretation of certain diseases and other occurrences described in the past, especially in the Bible, in relation to possible exposure to mycotoxins. The ten plagues of Egypt present good examples of how mycotoxins might have played a role in the events that followed the cataclysmic geoand meteorological phenomena that preceded the exodus of the Children of Israel from Egypt.


The origin of the so called magnetostriction effect, i.e., the deformation of a soft magnetic elastomer (SME) in response to a uniform magnetic field is discussed. We note that up to now there exists a number of cases, where the theory is unable to explain the facts well established for real SMEs. In our view, the essential issue, formerly not adequately accounted for, is the type of structural short-range order in the magnetic microparticle assembly. Two-dimensional model problems are formulated and solved, which demonstrate the validity of the hypothesis.


PENA, M.A., 1988: Primeras experiencias de lucha biologica contra Liriomyza trifolii (Burg.) (Dipt., Agromyzidae) con Diglypus isaea (Walk.) (Hym., Eulophidae) en las Islas Canarias. Bol. San. Veg. Plagas 14 (3): 439-445. Liriomvza trifolii causes severe damage in intensively cultivated zones in numerous costal areas of the Mediterranean and the Canary Islands. Owing to the facility with which L. trifolii acquires resitance to the insecticides we have made three trials to determine the efficiency of larval ectoparasite Diglyphus isaea, when used for control in greenhouses. The results show that not only is D. isaea a suitable candidate in the biological control of L. trifolii but that it is also necessary to increase the direct effects of the parasitism whose mortality is produced by adults of D. isaea in larvae of the leafminer.


Objective To observe the expression of bone morphogenetic protein-2(BMP-2) in renal arteriole,and to explore its effect to vascular lesion of diabetic nephropathy.Methods Adult Sprague-Dawley male rats were divided into diabetic group and control group.Paraffin sections of renal tissue of rats at the same time points were stained by routine methods and alizarin red,immunohistochemistry,hybridization in situ.Results(1)A bit of calcium salt deposited in renal arteriole at 4 week and a lot calcium salt at 24 weeks.(2) From 4 week,the number of BMP-2 staining and mRNA in diabetic renal arteriole was significantly increased as compared with control group.Conclusion(1) BMP-2 has already expressed in renal arteriole before the formation of vascular calcification.(2) Before vascular calcification,BMP-2 in diabetic renal arteriole is significantly upregulated,which indicates that BMP-2 is one of key regulating factors of diabetic vascular calcification.(3)Alteration of the expression of BMP-2 in renal arteriole may indicate that it participates in the development of DN.


Information on ductile and brittle failure modes is critical for proper design of timber connections in Crosslaminated Timber (CLT). While considerable research has been conducted in Europe and Canada on the ductile performance of connections in CLT, little is known about the brittle behaviour. This paper presents new information from testing programs and analysis performed in Canada and in New Zealand on the brittle performance of dowel-type fasteners in CLT. The testing programs have been designed to trigger brittle failure modes based on minimum end distances and fasteners spacings specified in the Canadian timber design standard. Timber rivets and bolts/dowels are covered under this study. At the time of writing of this abstract, the testing program is advancing and results will be available at the time of paper submission.


Complex spectral line shapes of J = 1 odd-parity autoionizing Rydberg series of Sn and Pb observed by Brown et al. [ J. Opt. Soc. Am.67, 607, 1240 ( 1977)] have been parameterized, using a simple expression that is based on multichannel-quantum-defect theory and has a form analogous to Fano's resonance formula.


We present the development of a dual parameter list mode 1K Multi-channel analyzer , which is capable of identifying coincident events within a 400nS window. This compact USB powered instrument has a microcontroller based design fabricated on PCB mounted in a durable aluminium enclosure measuring a mere 112 ∗ 60 ∗ 31mm. The inputs accept 0− 3.3V shaping amplifier signals with a rise time preset to 3uS(configurable) in accordance with the output characteristics of the portable gamma ray spectrometers we have already developed and presented at DAE-2018[1]. An elementary full-spectrum gating technique for coincidence demonstration was presented at RINP2[3], and this separate dual MCA approach overcomes its severe limitations.


Some novel chiral ligands (S)-(+) 1-substituted aryl-4(1-phenyl) ethylformamido -5-amino 1, 2, 3-triazole were prepared starting from 1-substituted aryl-4ethoxycarbonyl -5-amino-l, 2, 3triazoles and other reagents. They were used as catalytic chiral ligands in the silver (I)-promoted enantioselective allylation reaction of aldehydes with allyltributyltin. Catalytic asymmetric synthesis is a valuable method for the preparation of optically active substances(l). In this context, the stereoselective addition of organometallics to a carbonyl group has been extensively studied. In particular, the enantioselective allylation of carbonyl compounds is a challenging problem in organic synthesis. Although numerous important examples of the reaction using a stoichiomeric amount of chiral diamine have been reported(2), there is no method available for a catalytic process including chiral diamine having v-triazole. Recently Yamamoto reported a new catalytic enantioselective allylation reaction of aldehydes with allyltributyltin using a BINAP-silver (I) complex as a catalyst (3). To the best of our knowledge, this is the f e w case using a chiral silver (I) complex in a catalytic asymmetric reaction. This interesting result prompted us to design and synthesize other chiral ligands which are suitable for making chiral silver(I) complexes for catalytic asymmetric reactions. We wanted to try some chiral ligands containing a nitrogen atom because it is well known that nitrogen can easily coordinate to various metals such as Co, Cu, Zn and other metal giving stable chiral metal complexes(4) .Based on this concept, using (S)-(+)-l-phenylethylamine as a chiral scaffold, we started to prepare a series of the chiral (S)-(+) 1-substituted aryl-4(1-phenyl) ethylformamido-5-amino-l, 2, 3-triazole from 1-substituted aryl-4-ethoxycarbonyl -5-amino-l, 2, 3-triazoles and other reagents. In this paper, we wish to report the results using them as catalytic chiral ligands for silver (I)-promoted enantioselective allylation reaction of various aldehydes with allyltributyltin. Results and Discussion " To whom correspondence should be addressed Vol. 11. Nos. 3-4, 2005 Chira!(S)-(+) 1-substituted aryl-4-(l-phenyl)ethylfonnamido-5-amino-l, 2,3-triazole: a new xlass of chiral ligands for the silver 1-substituted aryl-4-ethoxycarbonyl-5-amino-l, 2, 3 -triazoles 1 react with sodium hydrate to give 1-substituted aryl-4-carboxyl-5-amino-l, 2, 3-triazole 2 in excellent yields. And then compounds 2 treatment using thionyl chloride to give 1-substituted aryl-4-carboxyl chloride5-amino-l, 2, 3-triazole 3. Compounds 3 reaction with (S)-(+)-l-phenylethylamine leads to (S)-(+) 1-substituted aryl-4(1-phenyl) ethylformamido -5-amino-l, 2, 3-triazole. After usual workup and purification by silica gel column chromatography, compounds 4 were obtained as colorless solids in moderate to good yield. In addition, using (S)-(+)-l-phenylethylamine as a chiral scaffold reacts with 1-substituted aryl-4ethoxycarbonyl-5-amino-1, 2, 3-triazole, we tried to synthesize the novel chiral ligand 4. No reaction took place between (S)-(+)-l-phenylethylamine and 1-substituted aryl-4ethoxycarbonyl-5-amino-1, 2, 3-triazoles. Structures of compounds 4 were confirmed by spectral data and microanalysis. These chiral ligands were used for the silver(I)-promoted enantioselective allylation reaction of aldehydes with allyltributyltin. The ee value of the products were determined by HPLC analysis using a chiral stationary phase column (Chiralcel OD and OJ) and the absolute configuration of the major enantiomer was assigned according to the sign of the specific rotation. Silver(I) triflate is a good catalyst for allylation of aldehydes, By means of the novel chiral ligand 4, the ee value can reach 42% in THF at -20°C. In addition, if the reaction was carried out below -30°C, the reaction proceeded very slowly. By means of these optimized reaction conditions, various aldehydes were used as substrates for this addition reaction and the corresponding sec-alcohol could be obtained in 39-65% yield and 13.5-42% ee with ^-configuration. These results are summarized in Table 1. The chiral compounds 4 a re quite stable chiral ligands. For chiral ligands 4, as expected the nitrogen atoms can coordinate to the silver(I) metal center to some extent giving a chiral environment, although the achieved ee value is low. This result strongly suggests that the coordination between the nitrogen atom and silver(I) metal plays an important role in this reaction. Thus, we believe that chiral ligand 4 is a diamine chiral ligand, namely, the nitrogen atoms can coordinate to the s ilver(I) m etal a ffording a c hiral silver(I) L ewis a cid. I η ο rder t ο ν erify t his speculation, we attempted to obtain a single crystal of the catalyst to confirm its structure. But despite extensive efforts, we could not obtain a single crystal of chiral silver(I) complex which could be subjected to X-ray crystal analysis.


Objective To assess the immunological status of patients with renal cell carcinoma (RCC), by analysing the proportion of cluster‐of‐differentiation 4‐positive (CD4+) cells showing intracellular cytokine production, i.e. interferon‐γ derived from T‐helper (Th) 1 and interleukin‐4 derived from Th2 cells, among peripheral blood lymphocytes from these patients


In this paper we show how Maximum Likelihood Sequence Estimation (MLSE) can be implemented in a Linear Periodic Time-Varying Multiple Access (LPTVMA) system. Assuming quasi-synchronous users, LPTVMA systems can be considered as Multi User Interference (MUI) free systems. Hence LPTVMA systems can be equalized. In multipath channels the equalization step uses a Zero Padding (ZP) technique. The equivalent channel to equalize is a zero-pad channel. For such zero-pad channels the MLSE can be efficiently implemented by using a parallel trellis Viterbi algorithm. The complexity of the MLSE can be further reduced because the padding zeros have known positions in the received signal. The proposed MLSE uses a periodic time-varying trellis. Thus the number of states of the MLSE can be reduced. The performances of LPTVMA systems using the proposed MLSE are evaluated by simulations.


The best mental health care service in my community is my local park. During our recent summer holidays, people of all ages were out in the park kicking and hitting balls, laughing, reading books, cuddling, doing tai chi, picnicking, pushing prams and walking dogs.


A major research university recently redesigned the new transfer student orientation program to provide more one-on-one attention to incoming transfer students. Concurrently, a new student seminar course specifically for transfer students was being implemented. These combined efforts were submitted to the National Academic Advising Association (NACADA) as a best practice for new transfer students and have yielded positive results in relation to students' connection to campus and satisfaction with orientation/advising. Additionally, analysis of both grade point average and first semester retention ofstudents enrolled in the new transfer student advising seminar have been higher than those not enrolled. The implementation of these practices, as well as their analyses, begin the discussion upon which further research efforts pertaining to transfer student transitions can be explored.


For some twenty plus years, infrared glasses have been one of the coming new materials. They have always had a lot of promise but, except for some military applications of bulk components, infrared glasses have not been commercialized. There is now a new wave of attempted commercialization with groups in France, and the USA building embryonic businesses in heavy metal fluoride fibers, and groups in Japan, USA, and Russia beginning to develop marketable chalcogenide fiber. Some work is also being done with modeled chalcogenide glass lenses. The major applications for the fiber are chemical sensing (spectroscopy), temperature sensing (pyrometry), and low-level laser power delivery. Telecommunications and long lengths of ultra-low loss fiber are not a significant factor in today's market, indeed the loss requirements for most applications are in the 100s of dB/km. Even at those levels, however, heroic efforts of raw material purification are often required to obtain the necessary properties. All infrared glasses have characteristics that make them more difficult to work with than conventional glasses. Against this is the advantage that these materials, to a greater or lesser extent, transmit in the infrared region of the spectrum and may be used to make fibers or optical components with characteristics that are otherwise not available.


Abstract Catalpa ovata is an ornamental tree species belonging to the Bignoniaceae family and also a valuable wood production plant. In this study, we sequenced the complete chloroplast genome of C. ovata and discussed its phylogenetic relationship. The complete chloroplast genome of C. ovata is 158,279 bp in size, comprising of a large single-copy (LSC, 85,004 bp) and a small single-copy (SSC, 12,675 bp) regions, separated by two inverted repeat regions (IRs, 30,300 bp each). The total GC content was 38.1%. The chloroplast genome contains 131 genes, including 86 protein-coding genes, 37 tRNA genes, and 8 rRNA genes. Phylogenetic analysis showed that the complete chloroplast genome sequence of C. ovata can be used as a super DNA barcoding to distinguish it from other plants. This study will provide genetic resources for species identification of C. ovata.


To address the route optimization problem of general aviation emergency rescue under major disasters, this study uses GIS and SuperMap for route selection of general aviation emergency rescue. And then it proposes a three-dimensional improved $\mathrm{A}^{\star}$route optimization algorithm based on the performance of rescue aircraft, so as to plan a three-dimensional shortest route that meets the actual complex flight situation. The traditional $\mathrm{A}^{\star}$ algorithm is known for its drawbacks such as high search node count, slow computation speed and restricted two-dimensional space. In order to overcome these challenges, this paper considering its performance limitations in actual rescue flights, such as steering radius, climb/descent angle, and then reducing search nodes from the horizontal and vertical directions, respectively. It proposes cost function improvements that consider actual rescue costs and heuristic function improvements that consider estimated rescue costs. This paper takes M-26 as the research object, simulation results show that the improved algorithm can scientifically plan the route of the rescue aircraft and effectively reduce the route planning time and planning length. The research results can provide a theoretical basis for improving the efficiency of rescue under major disasters and have certain reference significance.


As studied previously, the dialectal expression [teru] used in the words such as [kiteru], [saiteru], meaning the state of either 'finished' or 'continuing' is generally used in East Japan, and [toru] used in such words as [kitoru], [saitoru], meaning the state of 'finished'' and [joru] in such words as [kijoru], [sakijoru], meaning 'continuing' state are are spoken in West Japan, where they use two expressions each in its proper way.In this paper, the writer reports on the distribution of [t∫oru] used in such words as [kit∫oru], [sait∫oru], another expression meaning the state of 'finished', in Chugoku and Shikoku, West Japan.The expression [t∫oru] is spoken in Central Sanin, Yamaguchi prefecture, Central Geinan and South Shikoku, that is to say, in the fringes of Chugoku and Shikoku except Central Geinan. Each line of demarcation between [t∫oru] and [toru] roughly runs along the watersheds, but circumstantially that has been affected by traffic routes and by marital relations since old times. The use of the expression [t∫oru] in those [t∫oru] areas generally tends to fall off slowly, and it is mingling more or less with [toru] in each [t∫oru] area. In Fig. I, I can say that [toru] has generally extended westward from east, for the reason that [t∫oru] areas persist in the fringes of west, north and south, excepting east. Besides, in Fig. II, I see that [toru] has extended dualistically in 'Chugoku Shikoku' and 'Kyushu', for the reason that [toru] areas in 'Chugoku Shikoku' are separated from [toru] areas in 'Kyushu'.


The balanced scoring card is a series of financial and non-financial evaluation systems,in terms of financing,clients,internal process,learning and growth.It combines performance measurement and performance management.The display system reflects the scorecarding principle,and weights are decided by analytical hierarchy process to review the levels of learning,professional skills,and initiatives of the subjects.Then the major factors are singled out,and credibility of the evaluation ensured.The evaluation method provides with a new concept of performance evaluation of commercial banks.


Purpose: The study examines the effect of a role-playing intervention on the self-concept and career maturity of Chinese primary school students. The research issue is if a role-playing-based education paradigm improves students' self-concept and career maturity compared to conventional methods. Method: The study involved a sample of 112 children aged 10 to 12 years from a primary school in inland China, who were randomly assigned to either the experimental or control group. Adapted versions of the Chinese Career Maturity Questionnaire - Children (CCMQ-C) and the Chinese Self-Concept Scale - Children (CSCS-C) were used to assess self-concept and career maturity, respectively. ANOVA was used to analyze the data, with gender as a factor. Results: (1) The experimental group demonstrated significant improvements in both career maturity (t=-22.624, p<0.001) and self-concept (t=-12.973, p<0.05), while the positive effects of the intervention were sustained over time. (2) The experimental group, retested after one month, demonstrated a small but significant increase in career maturity (t=-2.383, p<0.05) and a significant elevation in self-concept (t=-12.57, p<0.05) compared to the pre-experimental test. In contrast, the control group did not experience significant changes in career maturity or self-concept after the same period. (3) Despite not being statistically significant (p>0.05), it was found that self-perception had a greater impact on women than on men, and this effect persisted even after one month. Conclusions: Role-playing was statistically significantly superior to traditional teaching methods in improving self-concept and career maturity, but gender was not affected.


The objective of this four-year research effort was to develop and test a methodology to estimate the economic impacts of median design. This report summarizes the activities and results for the entire four-year project. The primary task in the fourth year of the study was to collect post-construction data on the Texas Avenue corridor in College Station, Texas. The research team also collected customer survey information at five business types at the College Station corridor and performed interviews at several locations in Amarillo, Texas, where the raised median was removed. Final analyses on the entire eight-city data set from throughout Texas were performed in the final year of the study. The results of this research effort will provide insight to planners, engineers, and researchers investigating the economic impacts of raised median projects. This information is expected to be especially useful in communicating potential economic impacts to business and property owners prior to construction.


These notes arise from a minicourse given by the two authors at the Summer School on Poisson Geometry, ICTP, 2005. The main reference is our recent monograph "Poisson structures and their normal forms", Progress in Mathematics, Volume 242, Birkhauser, 2005. The aim of these notes is to give an introduction to Poisson structures and a study of their local normal forms, via Poisson cohomology and analytical techniques.


An embedded gateway of CAN/Ethernet is designed and used in remote video monitoring.The camera captures video signal which is compressed and exchanged via the CAN/Ethernet embedded gateway to the Ethernet.Its hardware system consists of the LPC2294 ARM MCU which includes four controllers of CAN bus,the RTL8019AS NIC and the transceiver of CAN field bus.The software system includes three parts: protocol transition module,CAN protocol module and Ethernet protocol module.In order to improve the stabilization and dependability of the system,the embedded RTOS μC/OS-Ⅱ is adopted.


This reports summarises and syntheses the results of household surveys on the use and trade in marula products from three sites in southern Africa: Makhatini and Bushbuckridge in South Africa, and the former Ovamboland in North-Central Namibia. A minimum of 60 and a maximum of 142 household interviews were conducted to establish the uses of marula, the quantities used/made of each marula based product, sales and income figures, cultural and social value, access and management issues, and resource availability in each of the three sites. The current role that marula plays in local livelihoods, and the positive and negative impacts of marula commercialisation on the social, financial, physical, natural and human capital of local households were explored. In this report the commonalities and differences between sites are highlighted. The survey forms part of a larger collaborative project on "Winners and Losers in NTFP Commercialisation" which seeks, through detailed study of selected species, to assess the social and economic impacts and benefits of NTFP commercialisation for the livelihoods of the rural poor. In all sites extensive use was made of a wide range of marula products including fruit, juice, beer/wine, kernels and wood. In addition, in Namibia, all households were also producing an oil from the kernels, mainly for cooking purposes. The cake made from the residue after oil extraction was also widely consumed or fed to livestock. The quantities of fruit used (on average just over one tonne per household per season) and beer/wine produced (on average between 150 and 350 l per household per season) were within the same range in all three sites, but households in Namibia were using up to ten times the amount of kernels (about 70 l per household per season) that households in South Africa did. In all sites, marula was found to form an integral part of the livelihoods and culture of residents, many of whom were living below the poverty line and dependent on natural resources to meet a range of basic needs. Of particular significance in all three sites were the neighbourhood marula parties where the beer/wine was drunk. These are important in building social networks and reciprocal relations, and are a key form of social capital. The potential demise of these 'get-togethers' was one of the main concerns linked to marula commercialisation. In South Africa, almost all households using marula harvested the fruit from the communal lands even when they had trees at home or in their fields. By contrast, in Namibia almost all marula trees were 'privately' owned and were found in people's fields. There were practically no trees in the communal lands. Consequently, in Namibia, a number of informal institutions have evolved to ensure equity and sharing of the marula resource. Beer/wine is brewed under the marula trees in owner's fields and is a social event in which other women partake and provide their labour in order to receive a share of the benefits. In South Africa, people generally make the beer/wine at home, sometimes with help from family members, using fruit collected from the commonage. Of significance, is that in South Africa anyone can access marula and use it at their own discretion, whereas in Namibia a certain proportion of villagers depend on the good will of friends and neighbours for marula products. In terms of commercialisation, only two households were selling marula products in Makhatini, where this activity was generally not supported by the community leadership. In Bushbuckridge and Namibia, households were selling both in the local market and to commercial producers. Fruit, kernels and beer/wine were sold in


The article presents a social analysis of global transformation processes. The global transformation processes are treated as contradictory. These processes are not as positive as the negative impact on the system of modern societies. Globalization as a popular ideology is based on the mythologizing of global neoliberal pseudo-integration, standardlization and unification. Thus it was formulated mythological discourse of global changes research. Apology of this mythological discourse became the intellectual foundation of globalization as a new social utopia. The article presents a critique of the mythological discourse of globalization. The ideology of globalization is interpreted as social dystopia.


The present invention provides methods of treating and preventing useful novel creatine analogs, and compounds and creatine deficiency by utilizing the pharmaceutical composition or formulation of the present invention to treat any creatine deficiency. In certain embodiments, the lipophilicity of the novel creatine analogs, in order to improve their bioavailability, which seek to increase.


retractable side barrier bed composed of parallel bars that may be grouped in the lower position along the lying surface. To minimize the height of the folded barrier in the lowered position, at least two bars (15, 16) have their own profiles and orientations as to allow their mutual embedding longitudinally.


A new algorithm is presented for constructing nearly optimal prefix codes in the case of unequal letter costs and unequal probabilities. A bound on the maximal deviation from the optimum is derived and numerical examples are given. The algorithm has running time O(t \cdot n) , where t is the number of letters and n is the number of probabilities.


We have measured nuclear quadrupole resonance (NQR) for 63Cu nuclei under high pressure up to 4.8 GPa. A linear increase in NQR frequency $^{63} \nu _{\rm Q}$ of 63Cu nuclei was observed below 3 GPa. However, $^{63} \nu _{\rm Q}$ deviates gradually from the linear relation above 3.5 GPa. The downward deviation is associated with a change of valence and consistent with the results of band calculations with the structural parameters under pressure. Antiferromagnetic (AFM) spin fluctuations are drastically suppressed with increasing pressure, whereas Tc increases from 0.7 K at ambient pressure to 1.64 K at 4.2 GPa. We have found that bulk superconductivity suddenly disappears at 4.8 GPa accompanied with a rapid decrease in the density of states at the Fermi level.


This chapter explores newcomer identity with a group of male undergraduates undergoing the transition into higher education. Through examining the performance of gendered identities among the male participants in an academic writing classroom, the chapter considers their orientation to academic community practices and the settling in process. In the classroom data hegemonic masculinity is primarily constituted through doing being a lad which not only serves immediate functions of acting cool and having a laugh, but also acts as a way of masking vulnerabilities and resisting institutional practices perceived as face-threatening and/ or alienating.


FFT is the fundamental unit of any signal processing system. Performance characteristics like speed, computational complexity and power consumption are dependent on FFT calculation. Optimizing FFT algorithm plays a significant role in optimizing the signal processing system. Hardware implementation of FFT follows a strict mathematical sense and hence has many problems with its VLSI realization. This paper presents the implementation of FFT algorithm based on pipeline architecture using the polyphase decomposition concept. The proposed architecture is designed to reduce the computational complexity and at the same time not compromising the speed of the overall DSP system. Polyphase decomposition is used to segment the long input sequence into P sub sequences by using decimation factor 'P'. The FFT of these segmented sequences is computed serially by using pipelined Radix-2 MDC architecture with higher throughput rate. Finally, results are combined to get complete FFT of original sequence by using (P-1) adders and multipliers. In addition to this, the proposed architecture also allows the calculation of any "even-length" point FFT within a specified range which depends on the decimating factor. The computational complexity is reduced by a large factor when compared with the existing FFT algorithms. The use of MDC architecture ensures higher throughput compared to other existing architectures. The proposed architecture is more efficient than existing in terms of throughput rate and maximum clock frequency.


A Smart spaces infrastructure is becoming popular due to high abstraction level of information that can be stored and retrieved from such environments. Since the amount of information is growing rapidly in modern world and one of the targets of the Smart spaces is to leverage the level of information between many information sources and consumers, it is crucial to provide efficient and reliable mechanism for information dispersing, processing and assembling around the number of physical or logical entities. Approach presented is targeted for the determining information signatures in Smart spaces which are the entities that are generated by means of isomorphic transformation thus represent information domain independent fragments and could be interpreted in some cases as a least meaningful information sets.


RCRA regulations require closure of permitted treatment, storage and disposal (TSD) facilities within 180 days after cessation of operations, and this may essentially necessitate decommissioning to complete closure. A more cost effective way to handle the facility would be to significantly reduce the risk to human health and the environment by taking it from its operational status to a passive, safe, inexpensive-to-maintain surveillance and maintenance condition (deactivation) prior to decommissioning. This paper presents an innovative approach to the cost effective deactivation of a large, complex chemical processing facility permitted under RCRA. The approach takes into account risks to the environment posed by this facility in comparison to risks posed by neighboring facilities at the site. The paper addresses the manner in which: 1) stakeholders and regulators were involved; 2) identifies a process by which the project proceeds and regulators and stakeholders were involved; 3) end points were developed so completion of deactivation was clearly identified at the beginning of the project, and 4) innovative practices were used to deactivate more quickly and cost effectively.


Ship navigation demands position fixing with a high degree of accuracy to enter the harbor mariner. The International Maritime Organization (IMO) has set a list of requirements which must be met by any electronic positioning system to be used on ships. The Global Positioning System (GPS) is most often the primary source of Position, Navigation and Timing (PNT) information. Due to the low levels of GPS signal strength at the surface of the earth and low jamming immunity, the recent concerns about vulnerability of GPS has sparked a renewed interest in the Loran PNT system. Enhanced Loran or simply "eLoran" is the latest version of Loran PNT for longstanding and proven series of low frequency navigation systems which are used to provide back-up capabilities to GPS in maritime navigation. In this paper, we present a detailed proposal study to establish eLoran navigation system for Egyptian maritime harbors. This study uses the performance requirements for both nonprecision approach (NPA) and maritime harbor entrance approach (HEA). The primary requirements of concern for NPA or HEA are the accuracy, integrity, availability and continuity. In the maritime sector, accuracy requirements are the most stringent and are considered the greatest challenge for eLoran establishment. Mitigating the sources of variation and error on Loran signal guided the design of eLoran. The simulation results for this proposal of Egyptian eLoran achieved the IMO's accuracy requirement of better than 20m.


From the Publisher:
E-Commerce Management: Text and Cases was designed to help the managers of today and tomorrow better direct the E-Commerce process by integrating business models, marketing, and Internet technology. The integration of text and cases helps make this a perfect choice for instructors seeking one primary text for use in both graduate and undergraduate level E-Commerce and E-Marketing courses. Each case study provides readers with an in-depth analysis of well-known companies that have developed into e-successes or e-failures.


AimThe aim of the study was to evaluate the diagnostic potential of immunohistochemistry using an antibody to the secreted mycobacterial antigen MPT64, specific for Mycobacterium tuberculosis complex organisms, on formalin-fixed biopsies from patients with pleural tuberculosis (TB) from a high TB and HIV endemic area. Methods and ResultsPleural biopsies from 25 TB cases and 11 non-TB cases were studied. Ziehl-Neelsen staining for acid-fast bacilli and immunohistochemistry with anti-MPT64 and anti-Bacille Calmette-Guérin (BCG) antibodies was performed. Nested polymerase chain reaction (N-PCR) for IS6110 was performed for comparison. Acid-fast bacilli were detected in only 2 cases and 3 biopsies showed granulomas with caseous necrosis. Immunostaining with anti-MPT64, anti-BCG, and N-PCR were positive in 20 (80%), 12 (48%), and 16 (64%) of the cases, and 0, 3 (27%), and 2 (18%) of the non-TB controls, respectively. The diagnostic validity of immunohistochemistry was calculated by comparison with N-PCR–positive TB cases and N-PCR–negative non-TB controls. The sensitivity of immunohistochemistry with anti-MPT64 and anti-BCG were 81% and 56% respectively, and the corresponding specificities were 100% and 78%. ConclusionsDetection of the MPT64 antigen by immunohistochemistry improves the diagnosis of TB pleuritis caused by M. tuberculosis complex organisms in patients living in HIV-endemic areas with atypical histology and negative staining for acid-fast bacilli.


We present a data-driven method to analyze functional magnetic resonance imaging (fMRI) time-series where multiple hypotheses are generated for inferential methods from the data itself without any assumptions on the time-series. The method does not require the number of clusters to be defined a priori. Activation detection is based on region growing which specifically suits the spatiotemporal characteristics of fMRI data. Results presented for simulated as well as real fMRI data show that the proposed method efficiently segments fMRI data into regions of distinct functional activity.


In 2008, the Integration and Trade Sector (INT) of the Inter-American Development Bank (IDB) designed an innovative project in Central America called International Goods in Transit (or TIM, its Spanish acronym), which has dramatically improved the speed and efficiency of border clearance for goods in transit. The TIM is an electronic system for managing and controlling the movement of goods in transit that harmonizes previously cumbersome procedures into a single electronic document, consolidating information and certifications from various authorities including migration, customs, and health/agriculture. The project is based on three main pillars: (1) process reengineering: TIM harmonizes multiple paper-based declarations into a unique and comprehensive electronic document that gathers all data needed by customs, migration, and phytosanitary agencies; (2) information technology: TIM connects the intranet systems of all agencies participating in the project. It includes state-of-the-art risk analysis and cargo control systems; and (3) cooperation: TIM improves cooperation within the country and between the different agencies operating at border crossings in the Mesoamerican region.


This paper considers the single machine scheduling problem with linear earliness and quadratic tardiness costs. The research on the version with an inserted idle time focused on an exact approach, while several heuristics were already proposed for the version with no idle time. These heuristics were then the basis for the development of new heuristic procedures for the version with idle time. Some improvement procedures were also considered. The new heuristics outperformed the existing procedures. A genetic algorithm provides the best results in terms of solution quality, but is computationally intensive. One of the backward scheduling dispatching rules provides results of similar quality and can quickly solve even large instances. The new heuristics were also applied, with the appropriate modifications, to the version with no idle time. Again, the new procedures provided better results than the existing heuristics. Therefore, the procedures developed in this paper are the new heuristics of choice for both versions of the considered problem. [Received 09 October 2008; Revised 02 February 2009; Accepted 20 February 2009]


Vehicle intelligent front light system is one of the advanced driver assistance systems. Vision based intelligent front light system is currently the research focus in this field. The purpose of this paper is to present a comprehensive survey of the vehicle front light system development and the latest vision based key technologies and proposals. By analyzing the significant disadvantages of traditional intelligent light systems, some possible improvement proposals and algorithms for lane, vehicle lamp recognition and track are provided. This survey shows that the Matrix-LED system could make the system more flexible and more effective.


Background The NOR-SWITCH study was a 52-week randomized, double-blind, non-inferiority, phase IV switch trial in patients with Crohn's disease (CD), ulcerative colitis (UC), spondyloarthritis (SpA), rheumatoid arthritis (RA), psoriatic arthritis (PsA) and plaque psoriasis (Ps) on stable treatment with originator infliximab (Remicade®, INX) and was funded by the Norwegian government. Previously, the primary analyses of the pooled indications have been published1. Objectives To investigate efficacy, safety and immunogenicity in RA patients treated with continous INX vs patients switched to CT-P13 (biosimilar infliximab, Remsima®) in the NOR-SWITCH study (explorative analyses). Methods Patients were randomized 1:1 to continued INX or switch to CT-P13. Serum drug levels were analysed in automated in-house assay. The primary endpoint was disease worsening according to disease-specific composite measures and/or consensus between investigator/patient leading to major treatment change. Exploratory subgroup analyses examined disease worsening and safety in RA. The primary endpoint was analysed using logistic regression, adjusted for diagnosis and disease duration. Results Demographics, occurence of disease worsening, change in disease measures and treatment-emergent adverse events (TEAE) were similar (Table). Serum drug levels for INX and CT-P13 were similar throughout the study (Figure)Table 1. Demographic and baseline characteristics (FAS), percentage of RA patients with disease worsening and change in disease measures during 52 weeks follow-up (PPS) Demographics and baseline characteristics INX CT-P13 Total number of RA patients PPS/FAS 30/39 30/38 Age (years) mean (SD) 59.9 (11.5) 60.4 (11.4) Females 31 (79%) 25 (66%) Duration of ongoing infliximab treatment (years) mean (SD) 8.2 (3.7) 9.9 (3.4) Concomitant immunosuppressive medication 27 (69%) 34 (89%) ACPA pos 25 (83%) 20 (74%) Disease worsening 95% CI of group difference after 52 weeks  All study patients 53 (26.2%) 61 (29.6%) -12.7–3.9%  RA 11 (36.7%) 9 (30.0%) -20.3–29.3% Change in disease measures from baseline  Physician Global Assessment of Disease Activity (0–10) -0.1 (1.3) 0.1 (1.4) -0.58–0.68  Patient Global Assessment of Disease Activity (0–10) 1.1 (1.4) 0.4 (1.9) 0.21–1.91  Log10 erythrocyte sedimentation rate (mm/h) 0.0 (0.3) 0.0 (0.3) -0.08–0.16  Log10 C-reactive protein (mg/L) 0.1 (0.3) 0.0 (0.5) -0.11–0.22  DAS28 0.2 (0.9) 0.2 (0.9) -0.30–0.50 TEAE (FAS) 94 62 Data are n (%), mean (SD) or median (25–75 percentiles). 95% CI, 95% confidence interval of the adjusted treatment difference. DAS28, Disease Activity Score in 28 joints. FAS, Full Analysis Set. PPS, Per Protocol Set. TEAE, treatment emergent adverse events. Conclusions Explorative analyses in the NOR-SWITCH study showed similar efficacy, serum drug levels and safety in RA patients switched to CT-P13 as those on continuous INX. The study was not powered to show non-inferiority within each diagnosis. References Jørgensen KK et al Switching from originator infliximab to biosimimlar CT-P13 compared to maintained treatment with originator infliximab (NOR-SWITCH): a 52-week randomized double-blind non-inferiority trial. The Lancet, in press. Disclosure of Interest G. Goll Consultant for: Orion Pharma, Pfizer, Novartis, Boeringer Ingelheim, AbbVie, I. Olsen: None declared, N. Bolstad: None declared, K. Jørgensen Consultant for: Intercept, Celltrion, Tillot, M. Lorentzen: None declared, C. Mørk Consultant for: Cellgene, AbbVie, Novartis, LeoPharma, ACOhud, Galdena Nordic, J. Jahnsen Consultant for: OrionPharma, Celltrion, Pfizer, MSD, AbbVie, Takeda, NappPharma, AstroPharma, E. Haavardsholm Consultant for: AbbVie, UCB, Roche, MSD, Pfizer, T. Kvien Consultant for: Biogen, BMS, Boehringer Ingelheim, Celltrion, Eli Lily, Epirus, Hospira, Merck-serono, Novartis, Orion Pharma, Pfizer, Sandoz, UCB


A person may be a heavy drinker and smoker for years and never notice any depreciation of vision. A diabetic person may go through life and suffer no visual disturbance. However, if the heavy smoker and drinker acquires diabetes, this relative immunity is apt to change. The report of the following case exemplifies this apparent relationship between diabetes and toxic amblyopia. REPORT OF CASE Mr. H. F., aged 42, was first seen on May 3, 1933, with the complaint of poor vision in both eyes. The onset was sudden, beginning three months before consultation. At this same time, the patient also learned that he had diabetes. He had been a heavy drinker and smoker for over fifteen years, consuming about a pint of whisky and smoking from fifteen to twenty cigars a day. The vision had apparently been normal all this time until about three months before consultation, when


<jats:p>Let <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1">
                        <mi>A</mi>
                     </math>
                  </jats:inline-formula> be a ring with identity, <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M2">
                        <mi>σ</mi>
                     </math>
                  </jats:inline-formula> a ring endomorphism of <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M3">
                        <mi>A</mi>
                     </math>
                  </jats:inline-formula> that maps the identity to itself, <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M4">
                        <mi>δ</mi>
                     </math>
                  </jats:inline-formula> a <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M5">
                        <mi>σ</mi>
                     </math>
                  </jats:inline-formula>-derivation of <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M6">
                        <mi>A</mi>
                     </math>
                  </jats:inline-formula>, and consider the skew-polynomial ring <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M7">
                        <mi>A</mi>
                        <mfenced open="[" close="]" separators="|">
                           <mrow>
                              <mi>X</mi>
                              <mo>;</mo>
                              <mi>σ</mi>
                              <mo>,</mo>
                              <mi>δ</mi>
                           </mrow>
                        </mfenced>
                     </math>
                  </jats:inline-formula>. When <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M8">
                        <mi>A</mi>
                     </math>
                  </jats:inline-formula> is a finite field, a Galois ring, or a general ring, some fairly recent literature used <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M9">
                        <mi>A</mi>
                        <mfenced open="[" close="]" separators="|">
                           <mrow>
                              <mi>X</mi>
                              <mo>;</mo>
                              <mi>σ</mi>
                              <mo>,</mo>
                              <mi>δ</mi>
                           </mrow>
                        </mfenced>
                     </math>
                  </jats:inline-formula> to construct new interesting codes (e.g., skew-cyclic and skew-constacyclic codes) that generalize their classical counterparts over finite fields (e.g., cyclic and constacyclic linear codes). This paper presents results concerning monic principal skew codes, called herein monic principal<jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M10">
                        <mfenced open="(" close=")" separators="|">
                           <mrow>
                              <mi>f</mi>
                              <mo>,</mo>
                              <mi>σ</mi>
                              <mo>,</mo>
                              <mi>δ</mi>
                           </mrow>
                        </mfenced>
                     </math>
                  </jats:inline-formula>-codes, where <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M11">
                        <mi>f</mi>
                        <mo>∈</mo>
                        <mi>A</mi>
                        <mfenced open="[" close="]" separators="|">
                           <mrow>
                              <mi>X</mi>
                              <mo>;</mo>
                              <mi>σ</mi>
                              <mo>,</mo>
                              <mi>δ</mi>
                           </mrow>
                        </mfenced>
                     </math>
                  </jats:inline-formula> is monic. We provide recursive formulas that compute the entries of both a generator matrix and a control matrix of such a code <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M12">
                        <mi mathvariant="script">C</mi>
                     </math>
                  </jats:inline-formula>. When <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M13">
                        <mi>A</mi>
                     </math>
                  </jats:inline-formula> is a finite commutative ring and <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M14">
                        <mi>σ</mi>
                     </math>
                  </jats:inline-formula> is a ring automorphism of <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M15">
                        <mi>A</mi>
                     </math>
                  </jats:inline-formula>, we also give recursive formulas for the entries of a parity-check matrix of <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M16">
                        <mi mathvariant="script">C</mi>
                     </math>
                  </jats:inline-formula>. Also, in this case, with <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M17">
                        <mi>δ</mi>
                        <mo>=</mo>
                        <mn>0</mn>
                     </math>
                  </jats:inline-formula>, we present a characterization of monic principal <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M18">
                        <mi>σ</mi>
                     </math>
                  </jats:inline-formula>-codes whose dual codes are also monic principal <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M19">
                        <mi>σ</mi>
                     </math>
                  </jats:inline-formula>-codes, and we deduce a characterization of self-dual monic principal <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M20">
                        <mi>σ</mi>
                     </math>
                  </jats:inline-formula>-codes. Some corollaries concerning monic principal <jats:inline-formula>
                     <math xmlns="http://www.w3.org/1998/Math/MathML" id="M21">
                        <mi>σ</mi>
                     </math>
                  </jats:inline-formula>-constacyclic codes are also given, and a good number of highlighting examples is provided.</jats:p>


The main concern of kinetic theory over the last 35 years has been to understand the properties of dense gases and liquids in terms of the interactions and motions of the molecules. For dilute gases, the Boltzmann equation has provided a basis for a kinetic description of nonequilibrium properties, and although there are still many unresolved questions, there is little doubt that this equation is the correct starting point for an understanding of dilute gases. In spite of numerous efforts, no one has yet succeeded in deriving a comparable equation for dense gases or liquids. Several generalizations to higher densities of the Boltzmann equation have been found, and many interesting and unexpected results have been discovered, but something we could call a systematic and complete theory has so far eluded us. I want to emphasize that this article does not pretend in any way to be a survey of kinetic theory. I shall only try to sketch a few of the most striking developments in the kinetic theory of dense flui...


To explore the protective function on nervous system of compound Chinese herbal and active ingredient,we has concluded positive effects on nervous system of compound Chinese herbal and active ingredient by collecting relative papers reported in recent years.This provides a reference to research further the mechanism of other compound Chinese herbal and active ingredient on protection of nervous system.


Treatment of 2-cyano-3-phenyl-2-pentenedinitrile with some heterocyclic diazonium salts afforded the corresponding heterocyclic hydrazones. Some of the latter hydrazones were converted into fused polyaza-heterocycles upon boiling in pyridine. Reaction of 2-cyano-3-phenyl-2-pentenedinitrile with phenylisothiocyanate gave a tricyano-thiole derivative which on treatment with hydrazonoyl chlorides and 1-(benzothiazol-2-yl)-2-bromoethanone furnished 1,3,4-thiadiazole and thiazole derivatives, respectively.


To restrict COVID-19, individuals must remain two meters away from one another in public since public health authorities find this a healthy distance. In this way, the incidence of "social distancing" keeps pace with COVID-19 spread. For this purpose, the proposed solution consists of the development of a tool based on AI technologies which takes as input videos (in real time) from streets and public spaces and gives as output the places where social distancing is not respected. Detected persons who are not respecting social distancing are surrounded with red rectangles and those who respect social distancing with green rectangles. The solution has been tested for the case of videos from the two Holy Mosques in Saudi Arabia: Makkah and Madinah. As a novel contribution compared to existent approaches in the literature, the solution allows the detection of the age, class, and sex of persons not respecting social distancing. Person detection is performed using the Faster RCNN with ResNet-50 as it is the backbone network that is pre-trained with the open source COCO dataset. The obtained results are satisfactory and may be improved by considering more sophisticated cameras, material, and techniques.


Gold nanoparticles are one classic and the most stable metal nanoparticles, which have attracted great interest due to their potential applications in electronic, optical materials and in catalysis [1]. The use of thiols, polymers, surfactants and other ligands as capping agents in the preparation of these particles can not only control the particle size and shape and prevent agglomeration but also can introduce functional groups to the surface, favoring the application in biomedical materials. What's more, thiol surfactants seem to be able to induce permanent magnetism in gold nanoparticles [2]. In order to study the influence of the thiol agent in this behaviour, we have prepared other capped metals. Here we present the synthesis, caracterization and magnetic behaviour of silver nanoparticles, comparing these results with those obtained from gold nanoparticles. What's more we present Au Mössbauer spectroscopy at 5 K for one sample of gold nanoparticles.


The work to be presented herein is a Computational Fluid Dynamics analysis of flow over a 20-degree half angle cone for a compressible air, with Mach number of 3.0. The problem to be solved involves formation of shock waves so that the general characteristics of supersonic flow are explored through this problem. Shock waves and slip surfaces are discontinuities in fluid mechanics problems. It is essential to evaluate the ability of numerical technique that can solve problems in which shocks and contact surfaces occur. In particular it is necessary to understand the details of developing a mesh that will allow resolution of these discontinuities. Results including contour plots of pressure, temperature, density and Mach number will show that CFD is capable of predicting accurate results and is also able to capture the discontinuities in the flow, e.g., the oblique shock waves. The global comparison between the numerical and the analytical values show a good agreement.


Dual-cavity macrocycles with extended π-conjugation are synthetically challenging yet attractive targets, exhibiting intriguing topologies and functional properties. In this work, a series of conjugated figure-of-eight macrocycles consisting of fused aromatic...


Affective computing has strong ties with literature and film studies, e.g. text sentiment analysis, affective tagging of movies. In this work we report on recent findings towards identifying highlights in movies on the basis of the synchronization of physiological and behavioral signals of people. The proposed architecture is utilizing dynamic time warping for measuring the distance among the multimodal signals of pairs of spectators. The reported results suggest that this distance can be indicative for the dynamics and existence of aesthetic moments in movies.


Abstract The photochemical formation of silicon-carbon double-bonded intermediates from phenyl, tolyl, naphthyl, 1-alkenyl and phenylethynyl substituted disilanes and their reactions are described. The silicon-carbon double-bonded intermediates generated from phenyl, tolyl and 2-naphthyldisilanes reacted with many organic substances to give 1:1 adducts; the mode of their addition reaction is very different from that of a hitherto reported dimethylsilaethene type of silicon-carbon double-bonded intermediates. Photolysis of 1-naphthyldisilane derivatives in the presence or absence of trapping agents led only to an isomer, 1-hydrosilyl-2-silylnaphthalene. The chemical nature of intermediates from vinyl- and α-styryldisilanes was rather similar to that of the thermally generated dimethylsilaethene-type intermediates. Photolysis of (pentamethyldisilanyl) phenylacetylene gave 1-silacyclopropene and 1-sila-1,2-propadiene which could be trapped by acetone or an alcohol.


George Eliot and Florence Nightingale were certainly two of the most influential women of their Era. George Eliot was known for her genius at writing intelligent novels that address societal and historical issues, and Florence Nightingale was known for her work in sanitation reform, hospital design, and as the founder of nursing as a profession. These two women met when they were thirty two years old, and from that meeting onwards, they shared a friendship and a high regard for each other's work. This paper explores the influence that Nightingale had on George Eliot's novel, Middlemarch, and it explores the influence Middlemarch had on Nightingale's work with educating nurses. George Eliot respected Nightingale's efforts in sanitation reform and hospital design. This respect is apparent in Middlemarch as George Eliot promotes sanitation reform and Nightingale's recommendations for hospital design. However, George Eliot also promotes germ-theory a subject that Nightingale opposed. This paper suggests that after reading Middlemarch Nightingale changed her position on germ-theory and took action to educate her nurses about contagions even though it was expedient for her to publicly dismiss the notion of contagions spreading disease in order to encourage support for sanitation reform. This paper demonstrate how respect and friendship between a writer and a social activists is able to promote an outcome that benefits many. TABLE OF CONTENTS Introduction ........................................................................................................................5 Chapter One Literature Review .......................................................................................7 Recent Scholarship on Nightingale's Criticism of Middlemarch .....................................7 Nightingale's position on Contagions Prior to Reading Middlemarch ...........................12 Nightingale Hires Croft After Reading Middlemarch.......................................14 Friendship, Respect and Influence............................................................. 16 Spiritual Crisis and Commonalty of Beliefs...................................................23 Nightingale as Dorothea in Middlemarch .....................................................25 Eliot's support of Medical Reform in Middlemarch..........................................28 Nightingale Reforms Nurses Training After Reading Middlemarch ......................30 Chapter Two Analysis ............................................................................35 Nightingale as a Model for Eliot's Dorothea..................................................37 Similarities Shared by Nightingale and Dorothea ...........................................38 Designing Cottages and Sanitation Reform...................................................41 Location of Middlemarch's Hospital ..........................................................46 Lydgate and Germ-Theory ......................................................................50 Nightingale's beliefs about Contagion Theory ...............................................51 Nightingale Hires Croft and Makes Changes to Nursing Education .......................53 Works Cited ........................................................................................55 Works Consulted ..................................................................................59 Appendix


This discussion explores the ways in which the multiple roles that analysts assume in their training years and beyond (analyst, patient, supervisor, supervisee, student, and teacher) are complementary and mutually enhancing. I suggest that our patients' personal growth, expanded and enhanced sense of self, and healing of old wounds are integrally linked to our own. Our work with our patients informs our personal analytic work, which expands our work with patients, deepening our capacity for knowing ourselves and others, in a continuous mutually enriching loop of psychoanalytic exploration.


The second generation antipsychotic of clozapine has superior efficacy compared to other antipsychotics especially for treatment-resistant schizophrenia. In up to 20% of patients receiving clozapine treatment, the side effect of obsessive compulsive symptoms or obsessive compulsive disorder occurs. These obsessive compulsive side effects sometimes cause cessation of the use of clozapine and sometimes causes difficulties in treating the psychotic symptoms due to dose reductions. This manuscript presents a case with resistant schizophrenia who developed obsessive compulsive disorder secondary to clozapine treatment and was successfully treated with clomipramine and aims to discuss the case accompanied by the literature.


The MESFET as an optically sensitive microwave element in MMICs has attracted much attention. The theoretical modeling of the device, however, needs more consideration. The authors propose an analytical model for the illuminated MESFET, complete in that all major contributions to the optical response are considered. The dependence of the response on bias conditions, the wavelength and intensity of the optical input, and the particulars of device structure, are incorporated in the model. The importance of the internal photovoltaic effect, which has not been properly modeled previously, is emphasized. The novel theoretical model is verified by experimental results. >


Psalm 53 is an adapted version of Ps 14, crafted to fit in among a cluster of psalms consisting of Pss 52–55. Each of these psalms is described in their respective headings as a "Maskil," while Pss 52 and 54 each also have a biographical link to the time of persecution of David by Saul. It is argued that various contexts have to be taken into consideration for a full understanding of Ps 53: the differences between Pss 14 and 53; Ps 53's links to the cluster of Pss 52–55; the connections it has with Proverbs, and the connections it has with the history of David in 1 Samuel via the two biographical notes in the cluster which seem to apply to it as well. When all these contexts are taken into consideration, Ps 53 appears to be an explication of certain texts in Proverbs, as if applying the truths of wisdom teaching to the experiences of David. A INTRODUCTION


While developing a measurement acquisition system to be used to retrofit aging aircraft with vehicle health monitoring capabilities, Langley Research Center developed an innovative wireless fluid-level measurement system. The NASA technology was of interest to Tidewater Sensors LLC, of Newport News, Virginia, because of its many advantages over conventional fuel management systems, including its ability to provide an accurate measurement of volume while a boat is experiencing any rocking motion due to waves or people moving about on the boat. These advantages led the company to license this novel fluid-level measurement system from NASA for marine applications.


In order to improve the prediction accuracy of short-term load, this paper puts forward a model of short-term load prediction (VPQPSO-BPNN) based on the optimized BP neural network. Firstly, by phase-space reconstruction, it conducts reconstitution for the historical data of short-term load, and then through VPQPSO algorithm, it finds the optimal parameters of BP neural network, and finally establishes the optimal short-term load prediction model, and test the model performance by simulation experiment.


Edge computing is becoming increasingly popular in artificial intelligence (AI) application development due to the benefits of local execution. One widely used approach to overcome hardware limitations in edge computing is heterogeneous computing, which combines a general-purpose processor with a domain-specific AI processor. However, this approach can be inefficient due to the communication overhead resulting from the complex communication protocol. To avoid communication overhead, the concept of an application-specific instruction set processor based on customizable instruction set architecture (ISA) has emerged. By integrating the AI processor into the processor core, on-chip communication replaces the complex communication protocol. Further, custom instruction set extension (ISE) reduces the number of instructions needed to execute AI applications. In this paper, we propose a uniprocessor system architecture for lightweight AI systems. First, we define the custom ISE to integrate the AI processor and GPP into a single processor, minimizing communication overhead. Next, we designed the processor based on the integrated core architecture, including the base core and the AI core, and implemented the processor on an FPGA. Finally, we evaluated the proposed architecture through simulation and implementation of the processor. The results show that the designed processor consumed 6.62% more lookup tables and 74% fewer flip-flops while achieving up to 193.88 times enhanced throughput performance and 52.75 times the energy efficiency compared to the previous system.


Purpose: To analyze the factors related to primary corneal graft failure after penetrating keratoplasty in the Corneal and External Diseases Section of the Federal University of Sao Paulo, Brazil. Methods: A retrospective study was performed using the charts of patients submitted to penetrating keratoplasty from July 1999 to March 2001. Cases of primary failure (group I) and patients submitted to the surgical procedure at the same period (group II) were selected and compared. Information collected from donors were age, cause of death, endothelial cell count, time between death and enucleation (T1), time between enucleation and preservation of the graft (T2) and time of tissue preservation until surgery (T3). Results: 164 patients were analyzed with 21 cases of primary failure (12.8%). The mean age of the donors of group I was 43.1 years (±22.0) and from group II was 47.9 years (±18.9). There was no statistical difference between the two groups considering the time intervals (T1, T2, T3). Causes of death included trauma, cancer and heart diseases. Conclusion: Differences in all analyzed factors were not significant between both groups. The difficulties in determining the causes of primary corneal graft failure suggests a multifactorial process involved in this problem. Well-trained Eye Bank staff and notifications about postoperative complications are important to decrease the primary failure incidence.


Abstract Improving the gasoline fuel combustion, reducing gasoline fuel consumption and reducing vehicles exhaust emissions pollution associated with gasoline combustion become growing interest locally and global-wide. To satisfy the exhaust gas emissions rules and regulations and reducing fuel consumption, it is very significant and critical to determine and understand the gasoline fuel quality impact on fuel consumption, air-fuel ratio (AFR), lambda (λ) and exhaust emissions of gasoline-fueled vehicles. Therefore, studying the impact of gasoline fuel quality on fuel consumption, the air-fuel ratio (AFR), lambda (λ) and exhaust emissions of gasoline-fueled vehicles is very important and necessary. A sensitive and detailed analysis conducted to analyze and determine the impact of gasoline fuel quality on fuel consumption, air-fuel ratio (AFR), lambda (λ) and exhaust emissions of gasoline-fueled vehicles. The study results indicated a direct impact of gasoline fuel quality on fuel consumption, the air-fuel ratio (AFR), lambda (λ) and some vehicle exhaust gases emission including carbon dioxide (CO2), oxygen (O2) and nitrogen oxides (NOx). Also, the results indicated the indirect impact of gasoline fuel quality on hydrocarbons (CxHy) vehicle exhaust emission. The results of this study can help in reducing fuel consumption, improving the quality of fuel combustion and reducing vehicle exhaust emissions.