Natural killer (NK) cells do not express variable antigen-specific receptors but are activated by combinations of germ-line encoded receptors. How activation is achieved and controlled during encounter of NK cells with target cells is unclear. We showed here that co-engagement of receptors NKG2D and 2B4 triggered synergistic activation of PLC-γ2, degranulation and cytotoxicity, which were controlled positively by Vav1 and negatively by the E3 ubiquitin ligase c-Cbl. Knockdown of c-Cbl blocked ubiquitylation of Vav1 and bypassed the requirement for synergy, as NKG2D and 2B4 could induce degranulation on their own. The enhanced degranulation obtained after c-Cbl knockdown was still Vav1-dependent. Inhibition of cytotoxicity through binding of CD94-NKG2A to HLA-E on target cells was independent of inhibition by c-Cbl. Therefore, natural cytotoxicity is controlled not only by dominant inhibitory receptors, but also by an activation threshold set by c-Cbl, which is overcome by Vav1-dependent synergy of coactivation receptors.


The utility model discloses an intelligent storage control system. The intelligent storage control system comprises a movable goods shelf, a drive motor, a goods shelf end signal module, carrying equipment, a carrying end signal module, a main control module, a remote network control module and a touch screen, wherein the drive motor is arranged on the movable goods shelf and is connected with the main control module by the goods shelf end signal module; the carrying end signal module is arranged on the carrying equipment and is connected with the main control module; the main control module is connected with the remote network control module; and the remote network control module is connected with the touch screen. According to the intelligent storage control system, the movable goods shelf is adopted; the movable goods shelf is moved by calling the operation information by the remote network control module, so that the carrying equipment can work conveniently, and therefore, the storage efficiency is improved; and meanwhile, as the storage density of goods can be increased by the movable goods shelf, the storage area of a warehouse is increased, and the inventory cost is saved.


Electronic Government (E-government) is becoming an important project that all levels of Chinese governments push hardly forward. E-government doesn't mean to abolish the actual government institutions in any case. It's rather to conduct those government affairs through net, which are applicable. This article expounded the status and the orientation of E -government, and made an analysis on the problems occurred in the process of development. In the end of the article some constructive suggestions on the development of Chinese E-government are put forward.


Caves provide a niche to several kinds of microorganisms. Nowadays cave ecosystem is attracting microbiologists to study the microbial diversity present inside the cave. These includes Bacteria, fungi, actinomycetes etc. In Chhattisgarh state of India there is a huge cave located in deep forest in Salewara mountain range known as Mandeepkhol cave which is nearly 100 km away from Durg dictrict. The longitude of cave is and latitude is. The present paper deals with the bacterial diversity found inside the cave. Thirty two different bacterial species were isolated from different parts of cave. Bacteria were got identified by help of morphological and microscopic characteristics.


A series of fluorinated trans-1,4-diphenylcyclohexane liquid crystal compounds are synthesized.The GC purity of the products reach to 99.8%,the yields are 67.0%.The properties are also researched.


Abstract:This article turns to the vast and versatile premodern tradition of assigning femininity to the church in order to unsettle modern and patriarchal constructions of Ecclesia as "Mother Church" or "Bride of Christ." Through an analysis of the second-century text The Shepherd of Hermas and Catherine of Siena's fourteenth-century Dialogue, this examination of Ecclesia—the feminine figure of the church—first identifies the strategies for feminizing the church practiced by premodern ecclesiastical reformers. Walsh then argues that a historical understanding of Ecclesia can strengthen broader feminist critiques and insights about ecclesiastical governance and gendering the divine by giving them a potent symbolic form. While avoiding a reinscription of gender as a primary or universal site of difference, this article reclaims Ecclesia as a powerful symbol and an ally of such feminist theological concerns as economic justice and resistance to patriarchal models of teaching authority and sacramental leadership.


A literature search for the past 2 years in the MEDLINE database, with the search terms "depression" and "stroke" and "rehabilitation," yielded 241 articles. Of these, some examined patients' access to effective services, and others showed clear correlations between functional impairment and depressive symptoms. Many presented in more detail the impact of depression on recovery, and others showed that depressive symptoms and illness behaviour can assist in predicting response to rehabilitation. There is clear evidence that active interventions reduce the incidence of depression among stroke survivors. This wealth of information indicates that this topic deserves our attention, especially given that we Canadian physicians already know how to treat depression. A single reference to the psychosocial impact of stroke on caregivers in the CMAJ editorial seems inadequate to capture the breadth and depth of this area.


In recent years, the interest in the assessment of hazard and risk of land sliding and in developing a warning systems and land utilization regulations aimed to minimizing the loss of lives and property without investing in long‐term, costly projects of ground stabilization has increased greatly. To be able to quantify both landslide hazard and risk a comprehensive landslide inventory is needed. A method used worldwide these days is to portray the spatial distribution of the landslides hazard and risks in maps. This paper presents in a case study for a territory from Republic of Moldova ‐ the types of works performed and the results for evaluating the trends in the evolution of exogenous geological processes (PGE) and the changes in the geological environment over time. All the results were used to make an annual forecast of the land sliding processes that could be use by interested state structures in order to establish a program of measures to protect the environment against sliding.


This paper presents a general electricity-CO2 modeling framework that is able to simulate interactions of the energyonly market with different forms of national energy market policy measures. We set up a two sector model where players can invest into various types of generation technologies including renewables, nuclear and Carbon Capture, Transport, and Storage (CCTS). For a detailed representation of CCTS we also include industry players (iron and steel as well as cement), and CO2 transport and CO2 storage including the option for CO2 enhanced oil recovery (CO2-EOR). The players maximize their expected profits based on variable, fixed and investment costs as well as the price of electricity, CO2 abatement cost and other incentives, subject to technical and environmental constraints. Demand is inelastic and represented via a selection of type hours. The model framework allows for regional disaggregation and features simplified electricity and CO2 pipeline networks. The model is balanced via a market clearing for the electricity as well as the CO2 market. The equilibrium solution is subject to constraints on CO2 emissions and renewable generation share. We apply the model to a case study of the UK Electricity Market Reform to illustrate the mechanisms and potential results.


Silicon phthalocyanines have been identified as a potential non-fullerene electron acceptor in organic photovoltaics. Bis(tri-n-butylsilyl oxide) silicon phthalocyanine ((3BS)2-SiPc) is shown to be a direct replacement for phenyl-C61-butyric acid methyl ester (PC61BM) with poly(3-hexylthiophene) (P3HT) in bulk heterojunction organic photovoltaics. Devices fabricated with a P3HT:(3BS)2-SiPc active layer displayed a power conversion efficiency (PCE) of 3.6% alongside a Voc of 0.76 V. These novel devices exhibited higher PCEs over a wide range of incident angles and light intensities, while also operating at longer wavelengths compared to devices with a P3HT:PC61BM active layer. This merits future investigation into commercial applications.


AXL and its corresponding ligand growth arrest–specific 6 (GAS‐6) are critically involved in hepatic immunomodulation and regenerative processes. Pleiotropic inhibitory effects on innate inflammatory responses might essentially involve the shift of macrophage phenotype from a pro‐inflammatory M1 to an anti‐inflammatory M2. We aimed to assess the relevance of the AXL/GAS‐6‐pathway in human liver regeneration and, consequently, its association with clinical outcome after hepatic resection. Soluble AXL (sAXL) and GAS‐6 levels were analyzed at preoperative and postoperative stages in 154 patients undergoing partial hepatectomy and correlated with clinical outcome. Perioperative dynamics of interleukin (IL)‐6, soluble tyrosine‐protein kinase MER (sMerTK), soluble CD163 (sCD163), and cytokeratin (CK) 18 were assessed to reflect pathophysiological processes. Preoperatively elevated sAXL and GAS‐6 levels predicted postoperative liver dysfunction (area under the curve = 0.721 and 0.722; P < 0.005) and worse clinical outcome. These patients failed to respond with an immediate increase of sAXL and GAS‐6 upon induction of liver regeneration. Abolished AXL pathway response resulted in a restricted increase of sCD163, suggesting a disrupted phenotypical switch to regeneratory M2 macrophages. No association with sMerTK was observed. Concomitantly, a distinct association of IL‐6 levels with an absent increase of AXL/GAS‐6 signaling indicated pronounced postoperative inflammation. This was further supported by increased intrahepatic secondary necrosis as reflected by CK18M65. sAXL and GAS‐6 represent not only potent and easily accessible preoperative biomarkers for the postoperative outcome but also AXL/GAS‐6 signaling might be of critical relevance in human liver regeneration. Refractory AXL/GAS‐6 signaling, due to chronic overactivation/stimulation in the context of underlying liver disease, appears to abolish their immediate release following induction of liver regeneration, causing overwhelming immune activation, presumably via intrahepatic immune regulation.


Diethyl succinate was prepared using succinic acid and ethanol as raw material,cation exchange resin NKC-9 as catalyst and with 3A zeolites as dehydration adsorbent.Effects of reaction conditions,such as mole ratio of ethanol to succinic acid,catalyst dosage and reaction time,were investigated.The optimum reaction conditions were identified,which are n(ethanol)∶n(succinic acid)=2.5∶1;catalyst dosage 6.0%(refer to total mass of succinic acid and ethanol);reaction temperature≤120 ℃;reaction time 3.0 h.Conversion of succinic acid by the process could achieve 98.8%,and activity of catalyst can be kept at 98.5% after 6 times repeated uses.


COCHRANE Nursing Care Field• The Cochrane Nursing Care Field writes exclusively forNursing TimesreadersA Cochrane review explored the evidence for brief interventions undertaken in schools to reduce substance misuse and other problematic behavioural outcomes for adolescents who use substances


The invention relates to a device (12) for controlling a continuously variable transmission which performs a feedback control so that an actual shift control value is equal to a target shift control value. The controller (12) is provided with phase advance compensation units (136, 137) for compensating the phase advance of a feedback control, phase delay compensation units (145) and , 146) for compensating the phase delay of a feedback control, and a phase compensation on / off determination unit (133) for stopping compensation by the phase delay compensation units ( 136, 137, 145, 146) when a state of unstable movement of the vehicle is detected and to restore the delay compensation when the state of movement of the vehicle has changed. A damping effect is achieved while ensuring the stability of the gearshift ratio of a continuously variable transmission which performs advance compensation.


When reviewing scientific literature, it would be useful to have automatic tools that identify the most influential scientific articles as well as how ideas propagate between articles. In this context, this paper introduces topical influence, a quantitative measure of the extent to which an article tends to spread its topics to the articles that cite it. Given the text of the articles and their citation graph, we show how to learn a probabilistic model to recover both the degree of topical influence of each article and the influence relationships between articles. Experimental results on corpora from two well-known computer science conferences are used to illustrate and validate the proposed approach.


Background: Pomalidomide is the newest IMiD approved for the treatment of patients with relapsed/refractory multiple myeloma (MM). Pomalidomide undergoes hepatic metabolism, and as such is not expected to accumulate as its predecessor lenalidomide, in patients with impaired renal function. Renal insufficiency is common in patients with myeloma, and is generally associated with poor outcomes. Previous studies have shown that renal dysfunction is not associated with increased toxicity in these patients. Here we evaluate the impact of renal and hepatic function on dose level of pomalidomide in our cohort of patients receiving ClaPD (clarithromycin, pomalidomide, dexamethasone). Methods: One hundred twenty patients with relapsed/refractory MM were enrolled in a phase II trial of ClaPD: clarithromycin 500mg PO BID, pomalidomide 4mg PO daily, dexamethasone 40mg PO weekly. We evaluated renal and hepatic function, as well as bone marrow involvement in all patients at baseline and throughout the study, and evaluated how this correlated with dose reduction requirement. Results: Renal function was evaluated based on creatinine clearance. Hepatic function was evaluated by albumin, bilirubin, and transaminases. At baseline renal dysfunction was seen in 37 (31%) patients, and hepatic dysfunction was seen in 7 (6%) patients. Neither was significantly associated with pomalidomide dose reductions. Treatment emergent cytopenias and dose reduction were not associated with baseline neutropenia. However, thrombocytopenia at baseline did correlate significantly with dose reduction (p Discussion: Lenalidomide is excreted by the kidneys largely unchanged, and renal dysfunction has been shown to result in elevated circulating levels producing greater myelotoxicity [BJH, 138: 640–643]. Pomalidomide is a newer generation IMID, which undergoes extensive hepatic metabolism by CYP1A2 and CYP3A4, and thus is predicted not to accumulate due to renal insufficiency. In our cohort of 120 patients, pomalidomide dose reductions were required for cytopenias, however baseline hepatic and renal dysfunction were not predictive. Coincident baseline renal dysfunction and thrombocytopenia likely represent patients with greater disease burden. Pomalidomide is now a standard for patients with relapsed/refractory MM, and dosing should not be limited by renal or hepatic dysfunction. Prospective studies evaluating the safety and efficacy of pomalidomide in special populations are warranted and ongoing. Disclosures Rossi:millenium: Speakers Bureau; celgene: Speakers Bureau. Mark:Millennium: Membership on an entity9s Board of Directors or advisory committees, Speakers Bureau; Celgene: Membership on an entity9s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Onyx: Research Funding, Speakers Bureau. Pekle:Millennium: Membership on an entity9s Board of Directors or advisory committees, Speakers Bureau; Celgene: Membership on an entity9s Board of Directors or advisory committees, Speakers Bureau. Perry:celgene: Speakers Bureau. Coleman:Onyx: Speakers Bureau; Millennium: Membership on an entity9s Board of Directors or advisory committees, Speakers Bureau; Celgene: Membership on an entity9s Board of Directors or advisory committees, Speakers Bureau. Niesvizky:Onyx: Membership on an entity9s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Millennium: Membership on an entity9s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Celgene: Membership on an entity9s Board of Directors or advisory committees, Research Funding, Speakers Bureau.


The natural history of diffuse large B-cell lymphoma (DLBCL) is heterogeneous. Several prognostic models have been investigated to predict treatment outcomes of patients with DLBCL. Endothelial activation and stress index (EASIX) is a surrogate of endothelial dysfunction as noted in various inflammatory states including malignancy. The elevated EASIX score was demonstrated to be associated with inferior outcomes in patients with multiple myeloma, low-risk myelodysplastic syndrome and patients treated with cell-based immunotherapy. However, the implication of EASIX on the prognosis of DLBCL is limited and warrants exploration.


Every child has human rights as well as the rights of adults, so respecting children's rights is the same as respecting human rights. This paper aims to compare the policy of imposing the death penalty on a child between Iran and Indonesia. This research is a normative legal research conducted by examining library materials or secondary data. The approach used is a comparative approach, which is to compare child protection laws between Iran and Indonesia. The regulation of criminal penalties against children in Iran is regulated in Article 91 of the Iranian Islamic Criminal Code in 2013 and in Indonesia it is regulated in Law Number 35 of 2014 concerning Child Protection and Law Number 11 of 2012 concerning the Child Criminal Justice System. The regulation of legal protection for children in Iran and in the State of Indonesia, when compared, has quite basic differences in several aspects of the provisions of criminal acts and the criminal system. In the criminal setting in Iran, it justifies the application of the death penalty for crimes committed by children under 18 years of age. In the last 7 years, almost all juvenile offenders who were executed were sentenced to death based on qisas and hudud verses. Meanwhile, in Indonesia, it does not apply the death penalty to children but prioritizes restorative justice and diversion which is intended to avoid and keep children away from the judicial process so as to avoid stigmatization of children in conflict with the law and it is hoped that children can return to the social environment naturally.


Orbitals of the extended Huckel theory have been used to calculate some EPR spin—spin coupling constants. The results are similar to those obtained by the hyperconjugation approach. The computer programs used make the method easy to apply, and the results show substantial agreement with experiment.


The current revolution in Materials Science leading to vast advances in pre-existing and emerging technologies had significantly impacted all aspects of our modern life. The continuous efforts in searching for new functional and smart materials facilitated the design of miniaturized and more efficient devices, and led to great advancements in pharmaceutical, medicinal, agricultural, energy related industries, and many more. Before employment in a given application, a newly developed material needs to be fully characterized and tested for efficient delivery and fulfillment of industrial and technological requirements. This calls for establishing experimental setups equipped with modern testing facilities that could be exceedingly expensive, and time consuming. In addition, the cost of materials for experimental work could be high in some cases. The financial limitations, however, make it difficult to construct such facilities for a large fraction of researchers worldwide, especially in nations with limited financial resources. Accordingly, computational techniques have been developed to provide efficient materials characterization, and design of smart materials and devices for practical applications at a relatively low cost. These techniques are also crucial in providing detailed information about the structural and physical properties of the material at the molecular level, thus allowing for better understanding of how the material functions, and facilitating the tuning and improvement of the material's characteristics for a specific application. However, comparison of the results of the computational techniques with experimental results is crucial to examine the reliability of the computational techniques, at least in its initial stages.


The utility model discloses a cigarette packing box. The cigarette packing box comprises a box body, and the box body is provided with a first pattern layer. The packing box further comprises semi-transparent wrapping paper wrapping the box body, and the semi-transparent wrapping paper is provided with a die cutting line matched with the appearance of the box body and a second pattern layer printed on the semi-transparent wrapping paper. The second pattern layer is provided with a blank part enabling patterns of the first pattern layer of the box body to be seen. A bonding piece is arranged on the left side or the right side of the semi-transparent wrapping paper. When the semi-transparent wrapping paper is arranged on the box body in a wrapping mode according to the die cutting line, anti-fake seal paper is arranged on the upper end face of the semi-transparent wrapping paper and the lower end face of the semi-transparent wrapping paper respectively so as to enable the upper end of the semi-transparent wrapping paper and the lower end of the semi-transparent wrapping paper to be fixed. The semi-transparent butter wrapping paper is adopted in the cigarette packing box to enable the cigarette packing box to have the damp-proof function; the patterns on the box body can be seen faintly through the butter wrapping paper, so that the sense of mystery is enhanced, eyeballs of consumers can be attracted easily, and the grade of cigarettes is improved.


The effective use of anaerobic passive treatment systems (APTS), such as sulfate-reducing bioreactors, to treat acid mine drainage will help to mitigate water contamination from mines located in remote areas as well as cut current treatment costs. One drawback to APTS has been an observed decline in longterm performance. Several environmental factors, such as initial metals concentration and temperature, may contribute to observed declines in sulfate reduction carried out by the microorganisms. APTS contain a complex microbial ecosystem, and metal toxicity could be indirectly affecting sulfate-reduction by inhibiting other important microbes. Previous research has found that organisms capable of degrading cellulose (cellulolytic-fermenters) are dominant within a sulfate reducing bioreactor (Pruden et al., 2005), and their ability to produce viable substrates for the sulfate-reducing bacteria is the rate-limiting step in sulfate reduction (Logan, 2003). This investigation examines the individual effect of zinc and copper, and then the combination of both metals, on a pure culture of cellulolytic fermenters, specifically Cellulomonas flavigena (ATCC 482). C. flavigena exhibited 50% growth inhibition between a copper concentration of 0.00188 mM and 0.0038 mM. Further investigation of growth inhibition within this range of copper concentrations is currently underway. Glucose consumption was also much less in the copper containing bottles, as expected due to the low biomass observed in these bottles. The pH remained relatively constant throughout the experiments, staying within an optimal microbial growth range between pH 6 and 7. Possible changes in solution phase metals concentration and organic acid production throughout the experiments were monitored, and these results will be available during the conference. Concentrations of Zn(II) at 0, 0.125, and 0.25 mM were also examined to determine the effects on cell growth for C. flavigena. The results for zinc toxicity and a binary metal mixture will be presented at the conference. Additional


PURPOSE
The purpose of this study was to report any differences found among the mean percentages of procedures performed by three types of dental providers for each type of service performed. The study focused on the types of services provided by dentists to Medicaid children in Virginia.

METHODS
Medicaid claims field for dental patients younger than age 21 were obtained and analyzed for fiscal years 1994 and 1995. Dental providers were categorized according to their practice: general practice (GP), pediatric dentist (PD) and public health dentist (PH). Each type of practitioner (GP, PD, and PH) was evaluated for percentages of diagnostic, preventive, and corrective services provided to their Medicaid patients. The preventive category was subdivided into preventive services (scaling, prophy, fluoride and oral hygiene instruction) and sealant services.

RESULTS
For each type of service, the mean percentages of procedures performed were compared among the three types of dental providers. The evaluation of the diagnostic procedure variable resulted in the finding that GP practitioners performed a significantly greater percentage of diagnostic procedures to their Medicaid patients than do PD and PH dentists (p < 0.0001). The percentage of preventive procedures performed by PD and GP dentists was not significantly different but was significantly lower than those performed by PH dentists (p < 0.0001). Finally, PD dentists performed a significantly greater percentage of corrective procedures than both GP and PH dentists (p > 0.0037).

CONCLUSION
Differences were found among the mean percentages of procedures performed by the three types of dental providers for each type of service performed.


D r. Kerr White, the former deputy director for health services at New York s Rockefeller Foundation, isn t likely to forget that talk he gave in 1976 on evidence-based medicine. He was telling his audience that only 15 to 20 percent ofdoctors interventions had been proven to do more good than harm, when a voice called out in midsentence: Ker r: you re a damned liar. You know perfectly well that it isn t more than 10 percent! Unmistakably, the voice belonged to Dr. Archie Cochrane noted British epidemiologist, pioneer of evidence-based medicine, and a man never afraid to speak his mind. It was Archie who famously observed in 1979 that the medical profession lacked a critical summary ofrandomised controlled trials (RCT)s. His words led to the formation of the first Cochrane Centre, launched 10years ago in Oxford, England. Today,there are 15Cochrane Centres around the world which facilitate the work ofan international group of researchers inspired by Archie s vision. Archibald Leman Cochrane was born in 1909 in Scotland. From his autobiography, One Man s Medicine, emerges the picture of an independent-minded, eternally curious person who possessed a quick wit and suffered no fools. (Having met Ernest Hemmingway, Archie dismissed him as an alcoholic bore.) Archie was also capable ofgreat kindnesses: as a medical officer in a prisoner-of-war camp, he held a screaming, dying Soviet soldier in his arms to comfort him; and later, as a medical professor, he discreetly counselled students who broke into tears due to unwanted pregnancies. Archie had a great desire to stimulate and challenge others. He was a delightful conversationalist, recalls Dr. Peter Elwood, a former colleague and friend, who succeeded Archie as director ofthe Medical Research Council Epidemiology Unit in Penarth, Wales. Sometimes, that desire backfired. At meetings he would occasionally attack a clinician, asking, Why did you not randomise? Dr. Elwood says. This often irritated the speaker rather than stimulating discussion. Whenever Archie indicated that he wanted to ask a question, I would duck! In those days, the RCT was a new innovation, Dr. Elwood adds, and many a clinician did not understand this research strategy, let alone what the single word randomise might mean. According to Bandolier editor Andrew Moore, Archie could think the unthinkable, question the unquestionable, and be thoroughly interesting. Moore has said that ifhe had to choose one book to take to a desert island, it would be Archie s Effectiveness and Efficiency: Random Reflections on Health Services. Ifthis seems an unusual choice, it s a tribute to Archie s wit and his call-it-as-you-see-it style. Effectiveness and Efficiency. published in 1972, caused a stir by arguing that the British National Health Service (NHS) could be vastly improved by using RCTs to test interventions. One chapter tells of a crematorium worker who found his job extremely satisfying because of the way in which so much went in and so little came out. Commented Archie: I thought of advising him to get ajob in the NHS. Archie began his colorful career by studying medicine in London in the 1930s. During that decade, he underwent psychoanalysis for two years and followed his analyst from Vienna to Holland. He also volunteered with a field ambulance unit in Spain during the Spanish Civil War.Along the way, he learned fluent German, Dutch and Spanish (and later, Russian and Yugoslav).


Objective: Investigate the influence of education levels on gains in executive function after dual-task (DT) training. Method: Exploratory study carried-out with 31 old women, who had ≥3 years of education and without cognitive deficits, as screened by the Mini-Mental State (MMS). The participants were distributed in two groups: group 1: 3 to 7 years of education (n=17) and group 2: ≥8 years of education (n=14). Measures of executive function ( Stroop, Addenbrooke's Cognitive Examination - Revised ( ACE-R ) , and Trail Making Test – B (B-Trails)) were obtained before and after training. The intervention protocol consisted of three weekly sessions of 50 minutes each and included cognitive and motor DT training, associated with walking, over 12 weeks. Results: ANOVA indicates that DT training improved the performance of Stroop (F=5.95; p= 0.02) and ACE-R (F=18.33; p <0.0001) tests, regardless of the education level. The effect of the ACE-R test group (F=14.65; p <0.001) and B-Trails (F=18.74; p <0.001) was verified. In none of the investigated tests, the interaction effects between groups and time (0.04<F<2.14; 0.15< p <0.95) was observed. Conclusion: DT training has the potential to generate effects and can positively improve the executive function of older women, regardless of educational level and may be used within clinical practice,


The utility model discloses a novel desk lamp. The novel desk lamp comprises a base, and a desk lamp body, a note board, a saving box and a pen container which are fixedly connected to the upper surface of the base, wherein the side surface in the front of the desk lamp body is fixedly connected with an electronic meter; the base has a hollow structure; a drawer is internally arranged in the hollow cavity of the base; and a sucking disc is arranged at the bottom of the base. The novel desk lamp has the advantages of simple structure, convenience and practicability.


Silk is a natural biopolymer with outstanding physical and mechanical properties.Raw silk fibers were took off the sericin at alkalescence environment in the experiment.Then,they were soaked in Simulated Body Fluid(SBF) of definite concentration to carry through experiment outside body.Finally,the configuration and component of the materials treated were analyzed by environmental scanning electron microscopy(ESEM) and infrared(IR) spectroscopy.The result indicated that the silk fibers took off sericin have better bioactivity and inductivity to mineral ion on surface.It could provide a certain academic enlighten for biological approach and application of the natural silk.


Seed priming is known as a seed treatment which improves seed performance under environmental conditions. Objective of this study was to evaluate the effects of different priming treatments on seed germination behaviour of two genotypes of Bromus under laboratory conditions to find out the most effective priming treatment. Seeds were treated with the following seed-soaking media: (i) unsoaked seed (control); (ii) hydropriming with distilled water for 4, 8, 12 and 16 hours, (iii) osmopriming treatments with PEG 6000 for Bromus tomentellus were -0.6, -0.8, -1.0 and -1.2 MPa osmotic potentials with duration of 12, 24 and 36 hours and for Bromus inermis osmoticpotentials were the same as B. tomentellus but duration of priming treatments was soaking seeds for 12, 24, 36 and 48 hours. Seeds of both genotypes were placed in liquid priming media at 25oC. Priming treatments significantly affected germination vigour of both genotypes. The response of both genotypes to different priming techniques approximately was similar. Osmopriming treatment (-0.6 MPa and 12 h) increased final germination percentage of B. tomentellus. Priming treatments increased coleoptile length significantly comparing to control but hydropriming for 4 h exhibited longer coleoptile than others. Higher vigour index was observed in hydropriming for 12 h but this difference was not significant with osmoprime treatment (12 h-0.6 Mpa). B. inermis produced more germinated seeds and vigourous seedlings than B. tomentellus but germination rate was higher in B. tomentellus.


by nail acrylates in Europe. An EECDRG study. Contact Dermatitis. 2018;78(4):254-260. 5. Scientific Committee on Consumer Safety. Opinion on the safety of cosmetic ingredients HEMA and Di-HEMA trimethylhexyl dicarbamate. https://ec.europa.eu/health/sites/health/files/scientific_committees/ consumer_safety/docs/sccs_o_214.pdf. Accessed September 24, 2019 6. Raposo I, Lobo I, Amaro C, et al. Allergic contact dermatitis caused by (meth)acrylates in nail cosmetic products in users and nail technicians – a 5-year study. Contact Dermatitis. 2017;77(6): 356-359. 7. Rolls S, Chowdhury MM, Cooper S, et al. Recommendation to include hydroxyethyl (meth)acrylate in the British baseline patch test series. Br J Dermatol. 2019;181(4):811-817.


A soap composition is provided to exhibit excellent moisturizing effect, antioxidant activity, immunity, skin firmness and anti-wrinkle effect and to show remarkable effect on atopic skin or sensitive skin. A soap composition comprises base oil, sodium hydroxide-deep sea water solution, and marine collagen. The base oil is one kind or greater selected from the group consisting of coconut oil, palm oil, caster oil, olive oil, sweet amond oil, grape seed oil, seed oil of Simmondsia chinensis, sunflower seed oil, camellia oil, avocado oil, calendula oil and rice bran oil.


Within a relativistic framework, the ground-state energy difference between left and right isomers of a chiral molecule is calculated. This energy difference is due to parity non conserving, electron-nucleus interaction. The influence of high-Z atoms, up to lead (Z=82) is investigated, for elements belonging to to groups 14 and 16, as well as Pt. Electron-nucleus overlaps are systematically calculated in a Dirac-Hartree-Fock scheme, showing a relativistic increase of the overlap of the order of 10 for Z∼80.


The cup-i products in semi-simplicial sets are developed following the work in [1]. The category of signed simplicial sets is presented, and using the cup-i product formulas, we find an operation in the cochain complex of a signed semisimplicial set that gives rise to the Steenrod squares. Explicit formulas are given to compute them.


In previous publications we described the kinetics of tryptophan uptake and of indole excretion during growth of Bacillus alvei (J. A. Hoch and R. D. DeMoss, J. Bacteriol. 90:604, 1965, 91:667, 1966). In this organism the action of a constitutive tryptophanase results in excretion, as indole, of a portion of the tryptophan taken up by the cell. An investigation of the indole excretion kinetics with isotopic tryptophan resulted in the hypothesis that tryptophanase served as an "overflow valve" to maintain the internal metabolic pool of tryptophan below a particular physiological maximal level. The maximal level was postulated always to be sufficiently low to permit endogenous synthesis of a small amount of tryptophan. This conclusion was adduced from a small but significant dilution of the isotope in excreted indole as compared with that expected from the labeled exogenous tryptophan, and from other lines of evidence (Hoch and DeMoss, J. Bacteriol. 91:667, 1966). Thus, even when tryptophan is present in excess, the metabolic pool of tryptophan is postulated to be of a constant size as a consequence of tryptophanase activity. The physiological reasons for maintaining a low level of endogenous tryptophan synthesis have been discussed (Hoch and DeMoss, J. Bacteriol. 91:667, 1966). Of central importance to the hypothesis is the need for showing that a low level of endogenous tryptophan synthesis does occur constantly. If the internal metabolic pool of tryptophan is of a constant size, the rate of tryptophan uptake into protein can be calculated as the value difference between excreted indole and tryptophan consumption. To evaluate the amount of tryptophan being incorporated in the absence of endogenous tryptophan synthesis, we used data obtained from experiments with a mutant unable to synthesize tryptophan. The mutant (TS-2) used in this study responds to anthranilic acid, indole, or tryptophan and has been described (Hoch and DeMoss, J. Bacteriol. 90:604, 1965). Tryptophan incorporation as a function of absorbancy of the culture is depicted in Fig. 1. The rate of tryptophan incorporation reaches a constant value (115 m,umoles per absorbancy unit) soon after the onset of tryptophan utilization from the medium. Since the mutant is unable to synthesize tryptophan, this rate represents the rate of total tryptophan incorporation per absorbancy increment of growth. It is now possible to relate this value to the rate of tryptophan incorporation observed in the wild-type organism. The results obtained are also shown in Fig. 1. By application of Student's t function, it can be demonstrated that the rate of tryptophan incorporation calculated for the wild-type organism (99 mAmoles per absorbancy unit) is significantly different (P = 0.058) from that obtained with the mutant. Since the rate of tryptophan incorporation from the medium is lower in the wild type than in the tryptophan auxotroph, the difference between the two rates must reflect the contribution of endogenous synthesis to the total rate of tryptophan incorporation. Figure 2 shows the calculation of the rate of endogenous synthesis in the wild-type strain by use of the difference between the observed rate and the assumed theoretical rate, the latter calculated from the results obtained with the mutant (Fig. 1). During the early phase of growth, the tryptophan requirement of the cell is satisfied from the internal metabolic pool of tryptophan and endogenous synthesis. When tryptophan utilization from the medium begins, the rate of tryptophan incorporation from the medium quickly reaches a constant value, as does the endogenous rate of tryptophan synthesis. The endogenous synthesis of tryptophan supplies about 141% of the total tryptophan requirement of the cell during this period. The underlying assumptions in a calculation of this kind are: (i) that tryptophan is either incorporated as such into protein or degraded via the tryptophanase catalyzed reaction, and no other mechanisms exist for tryptophan utilization; and (ii) that the mutant differs from the wild-type organism only in the inability to synthesize tryptophan. This assumption does not seem


In Old Russian written language we come across the words, the meaning of which cannot be derived from the context. Analyzing semantic and word-formative links of such words can help to determine the area of their functioning and to come closer to their definition.


Oil-induced mononuclear phagocytes (MN) were quantitatively assayed for various hydrolases as unfractionated suspensions of frozen and thawed cells. They apparently contain two proteases. The first, measured with urea- or acid-denatured hemoglobin, was similar to purified Proteinase I of lung with respect to pH optimum (pH 4), stability, hydrolytic and polymerizing activities, and reactions to various inhibitors. The second protease resembled chymotrypsin in its hydrolysis of glycyl-L-phenylalanine amide, acetyl-L-tyrosine ethyl ester and N-benzoyl-DL-phenylalanine-β-naphthol ester (BPN). With the latter, its pH optimum was between 5.0 and 5.8, and its action was inhibited by diisopropylphosphorofluoridate (DFP) and p-chloromercuribenzoate. When assayed under the above conditions, polymorphonuclear exudate cells (PMN) and red blood corpuscles (RBC) manifested little or no hydrolysis of either hemoglobin or BPN. MN also contained esterases that split methyl butyrate and β-naphthyl acetate. The pH optimum with the latter was 7.4, and its hydrolysis was partially inhibited by DFP, fluoride, taurocholate, and eserine. PMN had low esterase activity; RBC had little or none. MN, but not PMN or RBC, contained a stable lipase with a pH optimum of 6.1 in maleate buffer. Protamine, NaCl, heat, p-chloromercuribenzoate, ethylenediamine tetraacetate, taurocholate, and DFP were inhibitory, but no appreciable activation occurred in the presence of heparin or serum. Thus it possessed some of the characteristics of Korn's lipoprotein lipase, but not others.


AN IMPORTANT POINT IN THE IMPROVEMENT OF DRIVER TRAINING AND TESTING LIES IN INCREASED PROMOTION OF THE UNDERSTANDING OF TRAFFIC AND TRAFFIC PARTICIPATION BY DRIVING SCHOOL STUDENTS. THIS UNDERSTANDING CAN ONLY BE ACHIEVED BY SETTING IT APART WITH CONCRETE TRAFFIC SITUATIONS. THE PICTORIAL MEDIUM IS PARTICULARLY SIGNIFICANT IN THIS RESPECT. RULES OF GOOD BEHAVIOUR AND GENERAL PRECEPTS SHOULD REMAIN IN THE BACKGROUND. BY AN INCREASED USE OF FILMS IN THEORETICAL TRAINING AND ALSO IN TESTING THE INTEREST OF THE STUDENT MAY BE RETAINED. ALL MEASURES WHICH HELP TO MAKE THEORETICAL STUDY MORE GRAPHIC AND THEREFORE OF A LESS THEORETICAL NATURE WILL EVENTUALLY IMPROVE ROAD SAFETY.


Continuous phonation, though not always apparent to a listener, is frequently present in the speech of patients with congenital or long-standing profound hearing loss. Major effects of such continuous voicing are to transform unvoiced speech sounds into their voiced counterparts and to make more difficult the perception of the end of one word and the beginning of the next. These effects greatly reduce the intelligibility of speech. A procedure is described which has dramatically improved the speech of several hard-of-hearing patients with long histories of poor speech intelligibility.


The use of ultrasound for therapeutic and diagnostic applications has become common and it has been shown that High Intensity Focused Ultrasound (HIFU) could be a new therapeutic tool to relieve several cardiovascular diseases. For this reason, it is imperative to investigate different hydrodynamic and acoustic aspects related to focused ultrasound. In this context, an experimental study of acoustic streaming, was performed. In order to determine velocity field driven during ultrasound application, Particle Imaging Velocimetry (PIV) technique was used. Tests were conducted using a focused transducer that emits at a 500 kHz frequency, and which was immersed in a degassed and filtered water tank. Water was seeded with spherical Polyamide Seeding Particles. For PIV analyses and post processing, an open-source tool (PIVlab in MATLAB) [1] was used for image cross-correlation and velocity field resolution. Otherwise, these tests were performed with a parametric variation, namely, the imposed acoustic pressure (varying from 2.3 to 7.4 bars) and the seeding particles size (ranged from 5 to 50 μm diameter with a respective concentration of 0.09 to 0.18 g/m3). Experimental results allowed us to conclude that: (i) Ultrasound radiation force acting on the seeding particles can influence their behavior: According to the tests performed, 5μm-diameter seeding particles seem to be the most reliable and the most appropriate to characterize the flow, while 20 and 50μm-diameter particles are dispersed and removed from the ultrasound focal zone to the shearing zone due to interactions with the acoustic field. (ii) For ultrasound-subjected flow, streaming axial velocity is of the order of millimeters per second, and this streaming velocity is increasing with ultrasonic amplitude. As expected, the velocity field has the shape of the ultrasonic intensity field in the focal area, with a downstream shift of the maximal velocity position compared to the focal position.


Germanists in the post-holocaust era have assiduously searched the canon of German literature for other images besides the conventional demonization of the Jew. The legacy of Gustav Freytag's Veitel Itzig and Wilhelm Raabe's Moses Freudenstein – two of the most famous of such demonizations – however, remain representative figures for the image of the Jew in 19 th century German fiction, although in both novels, other Jewish figures appear which reveal further aspects of anti-Semitic stereotyping.


he FuShan tunnel is a large building that the south-to-north water transfer,This paper give a brief introduction of its deg the desin and construction technique method,The author proposes a few problems that demend notice,Sum up the large irrigation tunnel the experience of the different rock construction.


Continuous-time Delta Sigma Modulators (CTDSM) have "Implicit Anti-Aliasing" - is a commonly heard refrain in the data-converter design community. We show that this is not the case when a switched capacitor (SC) feedback DAC is used, thereby nullifying one of the principal advantages of continuous-time operation. We give an intuitive understanding of this phenomenon, and propose a power efficient circuit technique to improve alias rejection.


The MRS medium was used as basal medium,and the nutritional conditions for the biosynthesis of CLA by whole cells of the mixed bacteria strains(Lactobacillus plantarum and Lactobacillus acidophilus)were studied using single factor test and orthogonal test.The optimal nutrition for the whole cells converting LA to CLA were as follows:glucose concentration 20g/L, peptone concentration 15g/L,beef extract concentration 5g/L,yeast extract concentration 5g/L, sodium acetate concentration 7.5 g/L,tween-80 concentration 1.5 g/L,diammonium citrate concentration 3g/L,K2HPO4 concentration 3.93g/L,MgSO4concentration 0.58g/L,MnSO4 concentration 0.3g/L.The CLA concentration was up to 81.38μg/mL at the best culture condition, and the CLAwas increased by 11.34μg/mL compared with the basal medium.


The c‐Met oncoprotein is a cell‐surface receptor for hepatocyte growth factor (HGF). Signals through HGF and c‐Met have been appreciated for their crucial roles in the development of many cell types, including liver cells. The present study examined whether c‐Met is expressed in the thymus and whether c‐Met/HGF signals can regulate T‐cell development in the thymus. We have found that mRNA transcripts encoding c‐Met are expressed in mouse thymus. The c‐Met transcripts were expressed at higher levels in fetal and neonatal thymus than in adult thymus, and were mostly expressed by lymphoid cells rather than by stromal cells. Interestingly, the addition of HGF to fetal thymus organ cultures increased the generation of mature T cells expressing high levels of T‐cell antigen receptors. These results indicate that c‐Met is expressed in the thymus during early ontogeny, and that c‐Met/HGF signals can promote T‐cell development.


In this research the Kardar-Parizi- Zhang equation for surface growth has been analyzed in the regime where the nonlinear coupling constant, λ , is small (Edwards-Wilkinson equation) and also by using Fourier Transformations the finite size correction on the mean-square width has been calculated. It has found that the calculated interface width for 0 ~ → t behaves as


The effect of preirradiation with γ-rays from cobalt-60 and ultraviolet light from a low-pressure source on the exchange between benzene and heavy water in the presence of self-activated platinum oxide has been studied. Both rates of multiple and stepwise exchange processes are accelerated under these conditions. Of 14 oxides examined, including the Group VIII transition metals, platinum is the only one to catalyse exchange up to 130°. Preliminary experiments indicate that radiation-induced oxygen desorption from the surface of the oxide is responsible for the accelerative effect. Internal radiation sources such as tritium oxide also increase initial exchange rates. Cholesterol, naphthalene, dibenzyl, diphenyl, benzoic acid, and diphenyl ether have been studied with tritium oxide. The results can be rationalized in terms of π- complex mechanisms for exchange. A catalytic model for the mechanism of the radiation-induced effect is proposed.


A method based on the B-spline basis set is developed that significantly simplifies the Bethe-logarithm calculations for the atomic hydrogen. Without any auxiliary optimization and extrapolation, this method not only can calculate the Bethe logarithms of low-lying states to high precision using relatively small basis sets, but can also calculate high-lying Rydberg states efficiently. For the ground state, the Bethe logarithm is calculated to 24 significant figures using 450 B-spline functions. For high-lying Rydberg states, we can reproduce all the results of Jentschura and Mohr [Phys. Rev. A 72, 012110 (2005)]. DOI: 10.1103/PhysRevA.87.022510


Design has been described as making inspire decisions with incomplete information. True, we may use prior knowledge, we may even think we understand the causalites involved, but what really matters is exploration: of new forms, of new materials, and speculation about the response to the resulting effects. Essentially, this exploration has its own dynamics, involving intuition and spontaneity, and without which there is no design. But of course we all know that this is not the whole story. Design is different to 'craft'; to directly 'making' or 'doing'. It necessarily has to be predictive in order to anticipate what the consequence of the 'making' or 'doing' will be. Therefore we inevitably have to counter balance our intuition with a well developed sense of premeditation. We have to be able to reason about future events, about the consequence of something that has not yet being made. There is always going to be an advantage if this reasoning can be achieved with a degree of precision. So how can we progress from intuition to precision? What abstractions can we use to represent, externalize and test the concepts involved? How can we augment the cognitive processes? How can we record the progression of ideas? And, how do we know when we have arrived? Design has a symbiotic relationship with geometry. There are many design issues that are independent of any specific configurations. We might call these "pre-geometric" issues. And having arrived at a particular configuration, there may be many material interpretations of the same geometry. We might call these "post-geometric" issues. But geometry is central to design, and without appropriate geometric understanding, the resulting design will be limited. Geometry has two distinct components, one is a formal descriptive system and the other is a process of subjective evaluation.


This paper proposes a cloud rendering framework for three-degree-of-freedom-oriented standalone virtual reality headset which worked on wireless network to solve the shortcomings of VR devices using cables connections and insufficient local rendering capabilities. This framework not only solves the problem of the VR experience being affected by cables, but also improves the image quality of the standalone headset. In this solution, we use the standalone headset as the client, the Unreal Engine 4(UE4) as the rendering engine and the server combining Asynchronous TimeWarping (ATW) and Fixed Foveated Rendering (FFR) technology to achieve cloud rendering. The results show that the solution can support the 2560×1440 resolution. Experiments show that the framework can significantly improve the image quality of the standalone headset, and it can also maintain a frame rate of 70Hz.


Field monitoring of black beetle, Heteronychus arutor (F.), populations in Waikato pasture showed a strong association between black beetle numbers and the presence of Paspalum dilatatum Poir. Increasing paspalum gave higher adult numbers in spring resulting from increased overwintering survival, and in some seasons, reduced autumn dispersal. Numbers of larvae damaging pasture in February were directly related to adult numbers in September. Black beetle preferentially select paspalum plants in mixed pasture. This can place paspalum at a competitive disadvantage relative to other pasture species, but also permits the retention of higher adult black beetle numbers, even at low paspalum levels.


Abstract Forty two empirical studies over a 10 year period, on stepparenting adolescents, were assessed regarding their usage of theory. Although a majority of the authors responsible for the evaluated articles utilized some type of theory in their studies, 50% did not employ theory explicitly in either the introduction or discussion sections. Systems the ory and role theory, were the most frequent explicitly used perspectives. The findings of this study suggest that the link between theory and re search in family studies, more specifically in regard to stepfamilies and adolescents, needs more attention and focus. The authors of this article recommend future researchers utilize theories more explicitly to guide and connect ideas in regard to their empirical studies.


A current bleeding CMOS mixer with complementary transconductance stage is designed.The conversion gain of the mixer is increased and the flicker noise of the mixer is reduced by inserting the PMOS to form current bleeding circuit at the source ports of the switch transistors in Gilbert mixer.The circuit is designed using SMIC 0.18 μm CMOS process.The LO frequency is 1.571 GHz,RF frequency is 1.575 GHz,simulation results show the conversion gain of the mixer is 17.5 dB,NF is about 8.35 dB,and input power of third-order intercept point(IIP3)is-4.6 dBm.The mixer consumes 8.8 mA at 1.8 V power supply and the size of the mixer is 0.63 mm×0.78 mm.


A blend of polyester staple fibers and insulation fill materials useful as a replacement for natural down in articles such as outdoor apparel, sleeping bags, bedding, etc. The blend includes first, second and optionally third polyester staple fiber formats that differing in terms of average diameter. A length of substantially all the fibers of the blend is in the range of about 16 to about 63 mm, alternatively 20 - 40 mm. At least a majority of the fibers of the blend are opened. In some embodiments, some or substantially all of the fibers of the blend are crimped and/or include a lubricant (e.g., siliconized). One non-limiting example blend includes 20 - 30 weight percent of not greater than 1 Denier fibers, 20 - 30 weight percent of greater than 1 up to 2 Denier fibers, and 40 - 60 weight percent of greater than 2 Denier fibers.


For the Arctic exploration it is necessary to provide polar explorers with reliable high-quality communication equipment: satellite complex, router, wireless network. To supply with communications equipment and computer network a stable power supply is needed. A possible solution of the problem is the usage of alternative energy sources (solar panels, wind generators, batteries). In this paper we study the possibility of installing the system in the Arctic for making alternative power supply. Tests showed that during polar day the best way is to use solar panels, during the polar night vertical wind turbines are better.


Changes have occurred in private research in France since 1990, with the creation of in-house ethics
 committees defending the rights of laboratory animals.
 This voluntary process was initiated and carried through by the think tank GRICE (Groupe de
 Reflexion Interprofessionnel sur les Comites d'Ethique) which has so far overseen the creation of
 twenty or so ethics committees within private research laboratories.
 By harmonizing practices, stimulating exchanges on know-how and experiences, and improving
 communication between its different members, GRICE was able to unite the committees as well as
 win the support of the scientific community to implement its ethics principles.


Predictive process control is a method of regulation suitable for controlling various types of systems, which is based on the idea of using the prediction of future system behavior and its optimization. Normally, a system model is used to predict behavior, and therefore it is necessary for the correct function of predictive control to make its correct selection and determine its parameters so that the controlled system is described as accurately as possible. Another advantage of predictive control is the possibility of including signal restrictions directly in the controller. The result is the application of some elements of artificial intelligence in suitable areas of predictive control, especially the use of simple evolutionary algorithms in optimization and neural networks as nonlinear models. One of the chapters of the article describes the possibilities of using these elements. It is proved that in addition to classical optimization algorithms, it is also possible to use simple evolutionary algorithms for optimization of prediction, while the computational complexity can be comparable depending on the type of solved problem and settings. The article describes a suitable selection of model systems with slow dynamics, their derivation, and the creation of nonlinear models in the form of scalable neural networks. The potential advantage of this approach for the control of systems that are difficult to describe or for the control of systems whose mathematicalphysical description is not known. The chapter of the article also deals with the possibility of using the found models on real systems and determining the necessary conditions and requirements for their application.


The J-integral used as a ductile crack initiation criterion has been discussed for the impact loaded elastic-plastic 3PB specimens. The experimental method to measure or estimate the J-integral history has been investigated and its result has been compared to the obtained elastic-plastic values by the finite element model of this study. These numerical results and the experimental curves are found to agree closely. J-integral can be calculated by only numerical analysis with the finite element model. It is proved that simple calculation can be made in order to find the possible value of J-integral by crack mouth opening displacement(CMOD) in the dynamic nonlinear fracture experiment of 3-point bend(3PB) specimen. The property of elastic-plastic material is considered at different impact velocities. The J-integral may be estimated from the crack mouth opening displacement which can be measured directly kom photographs taken during impact experiments.


Manipulation of the EOF is essential for achieving optimal separations by MEKC. In this paper, we present an extensive investigation of the effect of common experimental conditions on the EOF observed in a capillary coated with poly(diallyldimethylammonium chloride) (PDADMA) polyelectrolyte under MEKC conditions. It was found that highly reproducible cathodal EOF is achieved approximately at or just below the conditional CMC value of SDS in the electrolytes used. At concentrations of SDS greater than the CMC the EOF is independent of pH. The impact of common organic modifiers (ACN, methanol, urea, β‐CD and nonionic surfactant) on the EOF behavior in both a PDADMA‐coated capillary and a bare silica capillary is compared. The suppressing effect of organic modifiers on the EOF is much stronger for coated capillary indicating that these compounds additionally reduce the negative charge density on the capillary surface due to alteration of the surfactant coating.


In 1993 Wickman reported that Olof E. Willman's publication of 1667 is trustworthy and that a meteorite in 1648 killed two seamen aboard a Dutch ship, Malacca, en route from Europe to the East Indies. Willman's description of the event has been rendered correctly in several publications in Swedish, but in Alexander von Humboldt's famous book Kosmos and in all other non‐Swedish publications it is incorrect, since they were based on Chladni's 1819 report which contains a mistranslation of Willman's 1667 text. Although a meteorite impact cannot be excluded, it is concluded that it is more probable that a volcanic bomb killed the two seafarers in 1648. At least 20 active volcanoes made the East Indiamen's voyage from Europe to Insulinde hazardous. Laufeld, S., 1994: Were two people killed by a meteorite in 1648? GFF, Vol. 116 (Pt. 1, March), pp. 37–38. Stockholm. ISSN 1103–5897.


Building regional brands of agricultural products has become an important means of agricutural production.It is necessary to build strong regional brands of agricultural products.There are rich resources of agricultural products in Hubei Province.It is an inevitable trend to accelerate the implementation of strong regional brands of agricultural products in Hubei Province.


MO: Well, I find it very lyrical, and I very much enjoy the very strict structuring of it. DY: I especially like the poems he writes for you. I took a class about two years ago that focused on George and Mary Oppen, not just George Oppen. I thought it odd at first that we would be focusing on the two of you, because I can't recall any other time the whole time I've been study ing literature that we focused on the life and wife of the poet along with the collected works. What is it that made that relationship "two"? I mean "two" in every way. You were with him. As he says, your words are "en tangled inextricably among my own." MO: Right. They were. For me as well as for him. I think it came from . . . really, you know we lived together from the time we were eighteen, and we wished the best for each other and helped each other and it was just a joint life. DY: What's the secret? (laughter) Is there any secret? MO: I don't know, we had an awful lot of fun. DY: You did. Whoever gets to write the biography of George and Mary Oppen is going to have a good time, I think. After reading your autobiog raphy, it seems more exciting than the lives of any of the other poets. MO: I think so. (laughter) DY: In Meaning a Life I noticed that you mention sailing and the sea a lot. At one point you say: "This experience is one which holds our world to gether." MO: The boat was very central and very important to us. We always had some kind of a little boat. And we could get just clear away and a part was


Arbitration is so prevalent that one can find arbitration agreements in many different types of contracts involving consumer goods, employment, bank deposits, credit cards, and a whole host of other arrangements. Frequently, businesses place non-negotiable arbitration agreements in their consumer and employment contracts, thereby, creating a mandatory arbitration system for disputes arising under such contracts. Courts readily enforce these arbitration agreements, mostly in furtherance of the Supreme Court-created federal policy in favor of arbitration. Some of the enthusiasm for arbitration is premised on allegations that it reduces litigation cost and provides speedy resolutions of disputes. But, there is much controversy about mandatory arbitration and some unresolved issues that are worthy of consideration by courts and others who are involved in this important debate. For example, there is still a disagreement over whether arbitration is a neutral process or one that is biased in favor of corporations and other repeat defendants. The available evidence is inconclusive, allowing arguments for both sides. Thus, some contend that the arbitration of employment disputes favors employers whereas others assert that arbitration offers benefits that employees might not otherwise obtain. The same lack of consensus exists over the arbitration of consumer disputes.

Despite the lack of clarity on these issues, opponents of mandatory arbitration do raise several important arguments about process dangers to consumers, employees, and other plaintiffs who must accept arbitration under adhesion agreements. This article discusses some of the dangers posed by mandatory arbitration.


Mesocolic plane surgery with central vascular ligation produces an oncologically superior specimen following colon cancer resection and appears to be related to optimal outcomes. We aimed to assess whether a regional educational programme in optimal mesocolic surgery led to an improvement in the quality of specimens.


Michael Schmitz (email@example.com) is a lecturer in mathematics at the University of Flensburg, where he received his Ph.D. in 2014. At the small university in the northernmost city of Germany he is busy educating ongoing primary and secondary mathematics teachers. Together with befriended mathematicians from several countries he regularly organizes and runs math camps for school kids in different locations. When he is not doing or teaching mathematics, he likes traveling, long distance running, reading, and spending time with his four girls (wife and three daughters).


Adults of pine root collar weevils, Hylobius radicis Buchanan, usually spend the daylight hours beneath the duff on the soil or in crevices near the base of the host. Adults are both thermophobic and photophobic. In an attempt to utilize these facts to cause a population reduction. the following treatments were assigned to 4 plots in 4 red pine, pinus resinosa Aiton, plantations: (1) undisturbed trees (checks), (2) branches pruned (up to 3 feet). (3) branches pruned plus duff removed around the base, and (4) branches pruned plus duff removed and ground scraped to bare mineral soil. Samples revealed that both egg and larval populations were inversely related to intensity of treatment, suggesting that the greater exposure to light or heat, or both, at the tree base, the less favorable was the habitat to the insect. At the end of the season, larval counts averaged 6.8, 4.1, 2.6, and 1.2 per tree, respectively, for the 4 treatments. Using a larval damage index, it was concluded that the branch-duff and branch-duff-soil treatments reduced larval populations, at least for the 1st year, below an economic level.


A branch-and-bound method for solving the min cut with size constraint problem
 is presented. At each node of the branch-and-bound tree the feasible set is
 approximated by an ellipsoid and a lower bound is computed by minimizing the
 quadratic objective function over this ellipsoid. An upper bound is also
 obtained by a Tabu search method. Numerical results will be presented.


Dispersionpolymerization isaversatile methodfor thepreparationof monodisper se polymer particles in the 0.5– 10 lm sizerange.Especially thepolymerization of styrene andmethyl methacr ylate in polar mediahasbeenextensivelystudied.To disperseparticlesstably, asuitablesteric stabilizerwasused,suchaspolyethyleneoxide, poly(vinylpyrrolidone), poly(2-ethyl-2-oxazoline), hydroxypropyl cellulose andpoly(acrylic acid). In this study, weemployedanaromaticpoly(amicacid)(PAA) asthestabilizer in thedispersionpolymerizationof styrene(S).PAA issolublein alkalineethanol-wat ermixturesduetothependantcarboxylic acidgroupsandworksasastericstabilizer for dispersionpolymerization.Furthermore,PAA is easily converted to polyimide (PI), which is one of the most importanthighperformancepolymersprovidinghighthermalstability, excellent mechanical properties,highsoftening temperaturesandgoodelectricproperties,andhasbeen utilized for aerospacematerials anddielectric insulatorin thesemiconductorindustry. After thepolymerization,the PAA incorporated into theparticlescanbeconverted into polyimide (PI) to yield core-shell PS-PI particles (Scheme1). ThusPAA couldplaytwo important roles,i. e., asasteric stabilizer duringpolymerization,andto improve mechanicalandthermal propertiesof particlesbymeansof imidizationof PAA after thepolymerization.For this purpose, PAA must be incorporated into the particles effectively. In general,moststabilizersfor dispersion polymerization are not incorporated into the particle and a large amount of stabilizer is neededto disperseparticlesstably. For an effective incorporationinto the particles, reactive stabilizersbearingpolymerizablegroups or radical transferagents(mercaptogroup) wereusedin thepolymerization. Thesecompounds stabilizedparticles even in low concentrationbecausetheyreactwith themonomerandget incorporatedinto the particles. In this study, the cationic comonomer 4-vinylbenzyltrimethylammonium chloride (VBA) was employed in the dispersion polymerization. VBA might copolymerizewith S, andabsorban anionic PAA effectively viaelectrostaticattraction. Communication: Dispersionpolymerization of styrene (S) and vinylbenzyltrimethylammoniumchloride (VBA) wasconductedin an ethanol-watermediumusingan aromaticpoly(amicacid) (PAA) asthestabilizer. Whenequimolar amountsof VBA and the carboxylic acid of PAA wereused,monodisperseparticleswith high PAA content wereobtainedquantitatively. The imidization of PAA on the particles proceededwith acetic anhydrideand N,Ndimethylaminopyridineto form core-shellPS-polyimide particles.


Provided results of CRMs certification. Tested CRMs of surface density, thickness and mass fraction of tin-bismuth alloy coating on copper using the state primary measurement standard of surface density and mass fraction of coatings GET 168-2015.


The 1993 Turkish Demographic and Health Survey (TDHS) was conducted to collect data on subjects like the level of fertility and the change in fertility in ever-married women younger than age 50 years infant and child mortality family planning and maternal and child health. A calendar was used in the 1993 TDHS to collect monthly data for each method used from January 1988 to the date of the survey. Findings are presented on contraceptive discontinuation rates contraceptive discontinuation rates by reason for discontinuation contraceptive switching behavior contraceptive failure rates method adoption rates following a live birth and the fertility effects of contraceptive use. A closing section of conclusions and recommendations summarizes discontinuation and switching behaviors for the IUD oral contraception condoms and withdrawal in the context of their probable relationship with family planning policies.


•Ideally, elections are the best way to proceed. They would enhance the status of the local Palestinian leadership, shifting the balance of forces within the PLO in favor of the insiders who are more supportive of interim arrangements. But any agreement on elections is probably months away; in the meantime, to avoid further deterioration of die situation, the United States should encourage an initiative to complement diplomatic efforts to reach an Israeli-Palestinian understanding on elections*


Deng Xiaoping's some opinions on ideological and politial work are the most important parts of Deng Xiaoping's Theory.The precious material riches for ideological and political work in the new stituations;riches for Deng Xiaoping's uncommon courage and wisdom of politics.It shows Deng Xiaoping's great quality and style of politics.


The influence of the miscut angle of GaN substrate on compositional and optical properties of InxGa1−xN epilayers (0.05<x<0.1) was examined using x-ray diffraction, photoluminescence (PL), cathodoluminescence, and Z-contrast scanning electron microscopy. We show that single atomic steps bunch during growth of InGaN and form macrosteps. Indium is incorporated differently at treads and risers of these macrosteps, which causes the layer to decompose and induces the formation of compositional growth striations. Since the growth step density increases with growing miscut angle of the substrate, the average indium concentration decreases and the average PL peak energy blueshifts and broadens with increasing miscut angle. The presented work enables understanding on microscopic scale effects related to the inhomogeneous distribution of indium in InGaN layers on miscut substrates, which is significant from the point of view of optoelectronic applications.


This study investigates symmetrical Lamb wave behavior across varying state-of-charge levels in lithium-ion batteries. Utilizing piezoelectric transducers, the research focuses on inducing and detecting Lamb waves in lithium-ion batteries. The outcomes uncover correlations between Lamb wave characteristics and state-of-charge variations, revealing insights into the potential of Lamb waves as indicators of internal changes in battery structures. Furthermore, the influence of chemomechanical alterations within battery structures on Lamb wave properties is explored. The insights gained offer valuable implications for understanding battery performance dynamics and internal transformations.


Abstract Thermo-mechanical characteristics significantly impact the operating performance of the friction pairs in hydro-viscous drive. A three-dimensional transient thermo-mechanical coupling model was established for investigation of the distributions and coupling relationships of the temperature, stress, and displacement generated by the combination of the thermal and mechanical loads under soft startup condition. Then, the time-dependent contact pressure and velocity were extensively examined, as well as their effects on the thermo-mechanical coupling characteristics. Finally, the effects of the material and structural parameters were analyzed by the one-factor-at-a-time method. The observations confirmed plastic deformation of the steel disc will occur when the steel disc and friction disc are, respectively, restrained at the outer and inner diameters. However, there is a low likelihood of plastic deformation of the friction lining occurring. The thermal load and constraint locations were also found to crucially affect the stress and displacement distributions. Moreover, the circumferential stress was determined to be the most important stress component, and can thus be used as a basis for judging whether plastic deformation will occur. The results provide theoretical reference for predicting the thermal characteristics of the friction pairs, as well as a foundation for selecting the material and structural parameters.


INTRODUCTION: ORALLY DISINTEGRATING TABLETS: Among the different routes of administration, the oral route of administration continues to be the most preferred route due to various advantages including ease of
ingestion, avoidance of pain, versatility and most importantly patient compliance. The
important drawback of tablets and capsules dosage forms for pediatric and geriatric
patients is they are facing difficulty in swallowing.
Nearly 35% of the general population, especially the elderly patients and children suffer from
dysphasia or difficulty in swallowing, which results in high incidence of noncompliance and
ineffective therapy. Swallowing problems also are very common in young individuals
because of their poorly developed muscular and nervous systems. Other groups who may
experience problems in swallowing conventional oral dosage forms are the patients with
tremors of extremities, mentally ill, developmentally disabled, non co-operative patients and
patients with reduced liquid intake plans or patients suffering from nausea. The swallowing
problems are also common in some cases such as patients with motion sickness, sudden
episodes of allergic attack or coughing and due to lack of water. AIM OF STUDY: Dexibuprofen is an non-steroidal anti-inflammatory drug (NSAID) , a propionic acid
derivative with analgesic and antipyretic properties. Dexibuprofen, (S(+)-ibuprofen) is a
pharmacologically active form and is more potent than Ibuprofen, which contains equal
quantities of R(−)- and S(+)-enantiomers. It is a bitter drug. Dexibuprofen inhibits
cyclooxygenases and activates peroxisome proliferators-activated receptors; both of these
actions result in reduced inflammation.
The aim of present work was to design and evaluate orally disintegrating tablets
(ODTs) containing Dexibuprofen using superdisintegrants and wherein its bitter taste is also
masked. OBJECTIVES OF THE RESEARCH WORK: Broadly, the work would endeavour to achieve the following objectives:
1. Selection of a model non-steroidal anti-inflammatory drug (NSAID), (Dexibuprofen)
based on pharmacokinetic parameters suitable for formulating into an ODT.
2. Selection of appropriate excipients including superdisintegrants (crosscarmellose
sodium, crospovidone, sodium starch glycollate) to develop the dosage form based on
physico-chemical properties and compatibility of the Active Pharmaceutical
Ingredient (API) and excipients.
3. Preparation of standard calibration curve for Dexibuprofen.
4. Formulation development of fast disintegrating tablet by direct compression
method.
5. Characterization and evaluation of the formulations
I. Pre-compression parameter:
a. Drug excipient compatibility studies: Comparison of drug and its
combination with various polymers with FTIR.
b. Evaluation of powder: Bulk density, Tapped density, Angle of repose,
compressibility index.
II. Post compression parameters:
a. Appearance and its dimension measurements b. Weight variation test
c. Wetting time
d. Water absorption ratio
e. Hardness test
f. Friability test
6. In vitro evaluation of formulation
a. In vitro disintegration studies
b. In vitro dissolution studies and curve fitting analysis
7. Optimization of the dosage form based on evaluated parameters to meet official &/or
pharmacokinetic specifications.
8. Stability Study of the formulation as per ICH guidelines. SUMMARY: Dexibuprofen is an non-steroidal anti-inflammatory drug (NSAID) , a propionic acid
derivative with analgesic and antipyretic properties. Dexibuprofen inhibits cyclooxygenases
and activates peroxisome proliferators-activated receptors; both of these actions result in
reduced inflammation.
Dexibuprofen is an NSAID that is advocated for the treatment to relieve pain
and inflammation associated with osteoarthritis, dysmenorrhea. Apart from pain it is
also used in treatment of pain associated with toothache and other painful problems
of the muscles and bones. Dexibuprofen is rapidly eliminated from the body due to
hepatic metabolism. Thus by formulating it as ODT its degradation by liver can be
bypassed and thus, its bioavailability can be increased
The present study is an attempt to develop and formulate fast dissolving tablets of
Dexibuprofen with superdisintegrants which disintegrates in matter of seconds in the oral
cavity, thereby reducing the time of onset of pharmacological action and to prevent the first
pass metabolism of Dexibuprofen.
In this system direct compression was used, Microcrystalline cellulose (MCC) is
used as a diluent, sodium starch glycollate (SSG), croscarmellose sodium and
crospovidone(CP) were used as superdisintegrants, aerosil are used as flow promoter,
magnesium stearate was used as lubricant, aspartame as sweetener.
The drug- polymer compatibility was confirmed by FTIR studies. The results
obtained by FTIR studies revealed that there was no chemical interaction between the pure
drug and excipients. Direct compression method was employed to formulate the tablets,
because of its cost effectiveness and due to reduced number of manufacturing steps.
The pre-compression parameters like bulk density, tapped density, Carr's 'index and
angle of repose were determined. The final formulation showed acceptable flow properties.
The post-compression parameters like the thickness, hardness, friability and in vitro
disintegration time, wetting time, water absorption ratio and in vitro drug release were carried
out and the values were found to be within IP limits.
The final optimized formulation of Dexibuprofen tablets containing 8% Sodium
starch glycollate (F12) revealed that formulated rapid dissolving tablets of Dexibuprofen were
effective and better to meet patient compliance. CONCLUSION: The present work was aimed to develop a stable, safe and convenient orodispersible
tablets of Dexibuprofen for rapid therapeutic action and to avoid first pass
metabolism.
Dexibuprofen is a BCS class II drug, So rapid disintegration of the tablet was desired
for achieving quick onset of action. For this purpose, suitable super disintegrants were added
and tablets were disintegrated within seconds.
Twelve formulations of fast dissolving tablets of Dexibuprofen were successfully
prepared using sodium starch glycollate, croscarmellose and crospovidone by direct
compression method. We have manufactured ODTs with quality and product consistent by a
production friendly direct compression technique which avoids costly technology, equipment
and lengthy manufacturing process.
The tablets were evaluated for parameters like thickness, hardness, friability, in- vitro
disintegration time, wetting time, water absorption ratio, and in- vitro drug release studies.
Based on the results, formulation containing 8% Sodium starch glycollate (F12) was
identified as ideal and better formulation among all formulations developed for Dexibuprofen
tablets.
In vitro release of optimized formulation of Dexibuprofen fast dissolving tablets of
F12 was found to be 98.86% drug release within 6 min.
The optimized formulation was subject to stability studies for 1 month by storing
them at 40C/75%RH. Results of physical appearance, hardness, friability, disintegration test,
and % drug release have shown that there was no significant change at storage condition.
They were within the limits as per stability protocol given in ICH guide lines in formulations.
Thus, Dexibuprofen oro-dispersible tablets were successfully developed.


Vehicle–road coordination is an important application scenario in the sustainable development of urban transportation. In this scenario, by navigating the vehicles in the road network, the vehicles can run more smoothly in the city, reduce unnecessary detours and parking, and realize energy savings and emission reductions. Although vehicle–road coordination in a large area has not been fully realized, people's travel is increasingly dependent on navigation. If the trips of most vehicles follow the same navigation suggestion in a short period of time, some sections in the given route of the navigation will bear excessive traffic load. In order to solve this potential problem, this paper relies on the vehicle–road collaboration scenario and combines the service level of the road network factors between vehicles to plan the travel path of the vehicle. This keeps the traffic load of each road section in the path at a reasonable level. Within the scope, considering the overall utilization of road resources and the efficiency of road network traffic, we established the road network evaluation index through the simulation comparison with the Dijkstra algorithm. Under the path planning method proposed in this paper, the total travel time of the vehicle is reduced by 23.4%, and the road network operation efficiency is improved by 6.6%, which proves that the method can be used. This method can effectively alleviate the load of the road network, improve operation efficiency, and finally achieve the purpose of energy saving and emission reduction.


GENESIS OF THE CARBONIFEROUS TROUGHS IN THE AREA OF THE NOW A RUDA GABBRO-DIABASE MASSIF In the present article the author discusses the genesis of the depressions occurring in the area of the Nowa Ruda gabbro-diabase massif, which are filled up with the Carboniferous deposits. Moreover, an opinion on their erosional origin is given, too. They would correspond to the filled up river valleys formed at the Devonian period. The initial stages of the filling up process of these valleys, this the age of the oldest deposits occurring in these forms, fall on the decline of the Lower Carboniferous period.


Currently, most wastewater treatment plants do not meet the legal requirements, especially regarding phosphorus and nitrogen contents. In this work, real primary urban wastewater (P-UW) was used as culture medium for the growth of Chlorella vulgaris. Experiments were carried out in batch photobioreactors at laboratory scale. To determine the maximum nutrient removal levels and the optimal pH value for C. vulgaris growth, the following pH values were studied: 5, 6, 7, 8, 9, 10, and 11. Additionally, two control experiments were conducted using UW and tap water at the same conditions but without microalgae inoculation. The operational conditions were agitation rate = 200 rpm, T = 25 °C, aeration rate = 0.5 L/min, and continuous light with illumination intensity = 359 µE m−2 s−1. Significant higher growth was obtained at pH = 7. The direct use of C. vulgaris for P-UW treatment demonstrated high removal percentages of organic (COD and BOD5 removal = 63.4% and 92.3%, respectively) and inorganic compounds (inorganic carbon removal = 99.6%). The final biomass was characterized by an accumulation of high energetic compounds, mainly carbohydrates, which ranged between 63.3% (pH = 5) and 82.8% (pH = 11) and represent a source of biofuels. These new achievements open up the possibility of new horizons in urban wastewater treatment.


Xnalysis of fluids in minute amounts or from sharply localized regions permits definition in corresponding detail of respiratory gradient,s and quantit,ies. The method here described permits sampling, transfer, and analysis of 0.7 t,o 0.14 c.mm. blood samples for carbon dioxide and oxygen wit,h an accuracy of kO.6 per cent for the larger samples and *1.5 per cent for the smaller samples. Nitrogen determinat)ions are less accurate. The analysis takes 15 to 20 minutes. Principle-The blood is sampled into a tine glass capillary and transferred directly to a mercury-filled micrometer burette needle of 1 c.mm. capacity, accurnt,e t'o approximately I in 3000. I<et,ween the buret,te needle a,nd the micrometer is interposed a mercury-filled detachable extraction tube which on its walls has a coating of dried acid and ferricyanide. The tip of the needle, containing the blood sample, is capped with wax, and the needle-extraction tube unit is detached from the micrometer and placed in a centrifuge tube with the lower end of the extraction tube dipping into the mercury. Ry the force of cent,rifugation, the mercury falls from the needle into the extraction tube, t'he blood dissolves the reagents, and the gases arc released into the vacuum space. R.eabsorption of the extracted blood gases is prevented by suddenly stopping the centrifuge, whereby the rising mercury shoot,s past the blood and reagent solution, sticking t,o the walls of the tube, leaving the extracted gas in contact only with mercury. The burette needle is detached from the extraction tube and put onto t,he micrometer burett,e. The wax tip is removed in a drop of acid solution and the gases are analyzed as described in t,he preceding paper (1). ApparcstzLs-The micrometer burette used is the same as that described in the foregoing paper (I). It is necessary for this method t,hat the micro plunger be made of st.ainless steel. If plain steel is used, lactic acid in the reagent,s will produce hydrogen bubbles in the burette needle and spoil the analysis. For the analysis of blood or other liquids the following additions are necessary. The eztruction tube (Fig. 1, A) is made from a 1.5 mm. bore glass tube. The shoulder is prepared wit,h t.he jig used for micro gas analysis (1). The burette end of the tube is ground flat and straight in a jig (Fig. 2, C, D,


The Web services are applications that perform specific tasks and are accessible via the network through a communication protocol. QoS plays an important role in finding out the performance of web services. Multi-layer perceptron neural network (MLP) is the most popular and widely used nonlinear network for solving many practical problems in applied science, biology, and engineering. In this paper, hybrid Particle Swarm Optimization (PSO) with MLP is performed for medical web-service classification. MLP performance is based on initial weights setting. Conventional training algorithms like Back propagation (BPP) and LevenbergMarquardt (LM) have slow convergence and local minima problems. Results show that the proposed method performs better accuracy, average precision, average recall and RMSE.


RFID is one of the most prominent identification schemes in the field of pervasive systems. Nonline of sight capability makes RFID systems much better choice than its contended systems (such as barcode, magnetic tape, etc.). Since the RFID uses wireless channel for communication with its associated devices, there should be some optimal encryption methods to secure the communicating data from adversaries. Several researchers have proposed ultralightweight mutual authentication protocols (UMAPs) to secure the RFID systems in cost effective manner. Unfortunately most of the previously proposed UMAPs are later found to be vulnerable against various desynchronization, Denial of Service (DoS), traceability, and full disclosure attacks. In this paper, we present a more sophisticated UMAP to provide Strong Authentication and Strong Integrity (SASI) using recursive hash function. The proposed protocol incorporates only simple bitwise logical operators XOR, Rot, and nontriangular function (recursive hash) in its design, which can be efficiently implemented with a low cost passive RFID tag. The performance analysis of the protocol proves the conformation of the proposed protocol with EPC-C1G2 passive tags. In addition to privacy and security, small chip area (miniaturization) is another design constraint (which is mandatory requirement for a protocol to be considered as ultralightweight authentication protocol). We have also proposed and implemented the efficient hardware design of the proposed protocol for EPC-C1G2 tags. Both the FPGA and ASIC implementation flows have been adopted. The FPGA flow is primarily used to validate the functionality of the proposed hardware design whereas ASIC flow (using TSMC 0.35 μm library) is used to validate the gate count. To the best of our knowledge, this is the first FPGA and ASIC implementation of any ultralightweight RFID authentication protocol.


This paper presents a new and efficient approach for capacitor placement in radial distribution systems that determine the optimal locations and size of capacitor with an objective of improving the voltage profile and reduction of real power loss. The solution methodology has two parts: in part one the loss sensitivity factors are used to select the candidate locations for the capacitor placement and in part two a new algorithm that employs cuckoo search algorithm is used to estimate the optimal size of capacitors at the optimal buses determined in part one. The developed algorithm is tested for IEEE 15 and 34 bus radial distribution systems.


ABSTRACT In this study, a hybrid method based on extreme learning machine (ELM) method and artificial bee colony (ABC) algorithm was proposed to forecast small hydropower plant generations. The input weights and biases of ELM were optimized by ABC algorithm to achieve more accurate forecasting results. The forecasting performance of the proposed method was compared with benchmark methods, namely backpropagation-based artificial neural network (ANN), radial basis function-based ANN, and long short-term memory. The experimental results verified that the proposed method significantly outperformed the benchmark methods. Specially, when the proposed method was compared with ELM, the improvement percentages in correlation coefficient, root mean square error, and mean absolute error values were calculated as being 6.20%-29.08%-26.29% for 14 days ahead and 5.47%-24.42%-20.33% for 21 days ahead, respectively.


Considering that application security is an important aspect, especially nowadays with the increase in technology and the number of fraudsters. It should be noted that determining the security of an application is a difficult task, especially since most fraudsters have become skilled and professional at manipulating people and stealing their sensitive data. Therefore, we pay attention to trying to spot insecurity apps, by analyzing user feedback on the Google Play platform and using sentiment analysis to determine the apps level of security. As it is known, user reviews reflect their experiments and experiences in addition to their feelings and satisfaction with the application or not. But unfortunately, not all of these reviews are real, and as is known, the fake reviews do not reflect the sincerity of feelings, so we have been keen in our work to filter the reviews to be the result is accurate and correct. This study is useful for both users wanting to install android apps and for developers interested in app optimization.


This paper propose a fast human detection algorithm of video surveillance in emergencies. Firstly through the background subtraction based on the single Guassian model and frame subtraction, we get the target mask which is optimized by Gaussian filter and dilation. Then the interest points of head is obtained from figures with target mask and edge detection. Finally according to detecting these pionts we can track the head and count the number of people with the frequence of moving target at the same place. Simulation results show that the algorithm can detect the moving object quickly and accurately.


After the First World War and the signing of the treaty of Versailles, the German army was forced to rethink its guidelines and restructure its forces. Generaloberst (Colonel-General) Hans von Seeckt had a special role in the development of the Reichswehr in the Weimar Republic. His influence was of such importance that he has been called the 'creator of the Reichswehr'. As an answer to Germany's changed geopolitical and military situation after the First World War, Seeckt developed the structure of the Neuzeitliches Heer or 'modern army', which distinguished itself fundamentally from the prevailing military doctrine in the German army. His vision of this modern army was of special importance to him and became the core of his innovative thinking, even if the restrictions of the Versailles treaty made sure it remained only a vision. This army would be characterized by a small number of soldiers, who would be well trained and equipped. This would enable the army to conduct a highly mobile war, which Seeckt saw as the key to success in future conflicts. This article examines Seeckt's model and the implications this would have had on a future war.


: This paper discusses two neomarxist theories of ecological crises – theory of metabolic rift and the second contradiction of capitalism theory. The goal of the paper is to present two critical theories and to confront them so similarities, differences, flaws and contributions of those theories can be identified. In the first part of the paper author classifies different approaches to ecological crisis and sustainable development in order to relate two neomarxist theories to other approaches to the topic. In the second part, author discusses theory of metabolic rift, which is a heuristic analysis of Marx's original work. In other words, this theory represents a new reading of the classic and tries to integrate it's new findings about envirnmental side of Marx's thought into a contemporary marxist theory. Third part of the paper is reserved for the second contradiction of capitalism, a neomarxist theory of economic crisis which can be applied as a theory of ecological crisis. Two theories are then confronted after which similarities and differences between them are pointed out. The author concludes the paper by stressing out the flaws and scientific contributions of the two theories.


The AWRE Punched Card Library of gamma scattering data is described. It is arranged on similar lines to the AWRE Library of Neutron Cross Sections. Full details of the card layouts are given. (auth)


In this paper, speech recognition techniques are applied to automatically evaluate children's performance in a syllable blending task. Word verification is performed to filter out utterances pronounced incorrectly. For valid words, forced alignment is applied to generate syllable segmentations and produce the corresponding HMM log likelihood scores. Normalized spectral likelihoods and duration ratio scores are combined to assess the overall quality of children's productions. Speaker-specific information is further incorporated to optimize performance. Experimental results show that the automatic system correlates well with those of teachers, but requires no human supervision.


Nondestructive assay (NDA) techniques are available both for fresh and spent fuel, but generally are too time consuming and do not uniquely identify an assembly. A new method is reported to obtain a signature from a magnetic scan of each assembly. This scan is an NDA technique that detects magnetic inclusions. It is potentially fast (5 min/assembly), and may provide a unique signature from the magnetic properties of each fuel assembly.


In the reform of PE,teachers should transform their concepts in teaching,namely,from imparting PE knowledge to the cultivation of PE ability,from unified teaching to individual teaching,from teacher-oriented to students-oriented,and from single teaching mode to the teaching mode with personality.


The paper addresses the question of literary genres that with their different strategies contribute to the formation of Xenophon's Anabasis and in particular the geographical and ethnographic sections. If the theme of travel brings with it a Homeric, and in particular Odyssean, memory, this memory is overlapped by the Herodotean model in the description of the customs of non-Greek peoples. Herodotus and Xenophon have different aims and interests and the paradigms they propose are different. The geographical and ethnographic sections can be investigated as examples of descriptions, which should not be considered as digressions, but interact with the narrative with their own strategy and literary code.