Introduction: Known common coronary artery disease (CAD) risk variants explain only 10% of the predicted genetic heritability of the disease, suggesting that important genetic signals remain to be discovered. Hypothesis: The 1000 Genomes imputation training set, and non-additive discovery screens, may allow detection of additional CAD-associated genetic variants that contribute to missing heritability. Methods: As part of the CARDIoGRAMplusC4D Consortium, we assembled 48 GWAS of CAD that included 1000 Genomes imputed data. These consisted of 60,801 CAD cases and 123,504 controls, 23% being of non-European ancestry. In each study, GWAS analysis was carried out by assuming an additive, dominant or recessive model of inheritance, and followed by meta-analysis to combine the GWAS results for each model. Results: After QC filtering, 9.4 million variants (91% SNPs, 9% INDELs) were available for meta-analysis. 29% of these were lower frequency variants (0.005 -8 , and outside of known CAD genomic regions) under the additive model were detected for 38 variants (8% INDELs) with imputation info score of 0.94 [0.88-0.96] (median [IQR]). Of note, 34% of novel variants (N=13) were of low allele frequency (MAF Conclusions: These findings demonstrate the value of using a global imputation training set to enhance coverage of low allele frequency and incompletely tagged variants. Consideration of non-additive models of inheritance enabled identification of additional genetic variants associated with CAD.


File formats have a tendency to proliferate and the tools required to convert between formats tend to lag behind. In addition, fle conversion is often inadequate and information lossy. The Unifed File Container (UFC) is a framework for allowing existing fle formats to share content, structure, and presentation without necessarily using the same underlying fle format. Any proposed framework clearly needs to allow for modern functionality such as collaborative editing, undo/redo, version control, compound documents, object linking and embedding, document preservation, format obsolescence, cascading styles, and more. The UFC attempts to address or bypass most of these issues.


NICOLETE, V. C. Duffy blood group polymorphism and naturally acquired IgG antibodies to Plasmodium vivax Duffy binding protein (PvDBP) in rural Amazonians. 2012. 96 p. Masters thesis (Biology of the Relation Pathogen-Host) – Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, 2012. In Brazil 99, 9% of the reported cases of malaria originate from Amazon region and 90% of them are due to Plasmodium vivax. To invade their target cells, young erythrocytes knwon as reticulocytes, P. vivax merozoites recognize specific receptors on the host cell surface. One of the major parasites ligands is the Duffy binding protein (PvDBP), expressed in micronemes, which binds specifically to a erythrocyte membrane glycoprotein known as Duffy blood group antigen/receptor for chemokines (DARC). Interaction between cysteine-rich domain II of PvDBP and DARC is crucial for red blood cell invasion and DARC-negative individuals are usually resistant to blood-stage infection with P. vivax; therefore, PvDBP is a major vaccine candidate antigen. Here, we investigated IgG antibody responses to three recombinant proteins derived from PvDBP and MSP119 (19 kDa C-terminal region of the merozoite surface protein-1 of the P. vivax), in 343 subjects exposed to hypoendemic malaria in the Amazon Basin of Brazil. Both recombinant proteins Sal III-IV-GST and Sal III-His contain part (either domains II to IV or domain II alone) of the Sal I variant of PvDBP fused to either GST or a histidine tail, while OII-His contain the domain II of the PNG-O variant fused to a histidine tail; recombinant proteins Sal III-His and OII-His (but not Sal III-IV-GST) were refolded to reproduce the native conformation of PvDBP. IgG antibodies to Sal III-His, OIIHis, Sal III-IV-GST and MSP119-GST were found in 43,7 %, 39,0%, 14,3% and 38,8% of the subjects, with a strong positive correlation between antibody levels to the Sal III-His and OIIHis but a poor positive correlation between levels of antibodies to these refolded proteins and non-refolded Sal III-IV-GST (which shares the same domain II sequence with Sal III-His) and MSP119-GST. Current P. vivax infection (as detected by microscopy or PCR) and cumulative exposure to malaria (as determined by the lenght of residence in endemic areas) were significantly associated with increased antibody responses. The Duffy genotypes FY*AFY*B and FY*B ES FY*B ES [DARC negative] were the most and least common genotypes, respectively. As expected, FY*B ES FY*B ES individuals were less likely to have antibodies to PvDBP, but we found similar proportions of seropositive subjects with the FY*A*FY*A, FY*AFY*B ES , FY*B*FY*B and FY*BFY*B ES genotypes. Sequence analysis revealed several region II PvDBP variants in 41 local P. vivax isolates. The most common of them (found in 28,8% isolates) differs from Sal I and PNG-O alleles in six amino acid codons (including N417K change, which has previously been shown to be part of a linked haplotype that alters PvDBP sensitivity to inhibitory antibody). No Sal I-type variant, from which a PvDBP-based vaccine prototype currently under clinical testing has been derived, was found in local parasites.


At the outset, it seems essential to provide a working description of some of the terms that comprise the title of this article. The term diagnosis, borrowed by educators from the medical profession, means essentially the same thing as it does in medicine. That is, "the act or art of identifying an anomaly from its signs or symptoms." In the case in point, by identifying signs or symptoms we get an indication of a child's readiness for reading. The term reading readiness has been described in a number of ways; however, these descriptions appear to be more alike than they are different. The Dictionary of Education appears to synthesize these various descriptions by defining reading readiness as "the physical, mental, and emotional maturation necessary for undertaking instruction in reading at a given level of development" (Good 1959).


The invention relates to a short-circuit preventing device of a voltage dependent resistor of a large-discharge-current surge protector, comprising a voltage dependent resistor and a heating fuse wire, wherein one end of the heating fuse wire is connected with one end of the voltage dependent resistor, another two ends of the heating fuse wire are respectively connected with a failure indicator and a signal processor, one end of the voltage dependent resistor is connected with a current transformator, the current transformator is connected with the signal processor, and the signal processor is connected with a remote-signalling contact point. The invention can process the voltage dependent resistor and can be safely used in a circuit without installing a miniature breaker or a fuse wire additionally.


While checkpointing is typically combined with a restart of the whole application, localized recovery permits all but the affected processes to continue. In task-based cluster programming, for instance, the application can then be finished on the intact nodes, and the lost tasks be reassigned. This extended abstract suggests to adapt a checkpointing and localized recovery technique that has originally been developed for independent tasks to nested fork-join programs. We consider a Cilk-like work stealing scheme with work-first policy in a distributed memory setting, and describe the required algorithmic changes. The original technique has checkpointing overheads below 1% and neglectable costs for recovery, we expect the new algorithm to achieve a similar performance.


Using an image plane introduced previously by Liu [4] the original shape design problem of heat conduction is transformed into the one with known boundary and a pair of complementary variational principles (VP) for it with complicated boundary conditions are established in terms of the heat stream function and the temperature function respectively. Based upon these VP some finite element solutions to the shape design problem of heat conduction are presented. Finally, a very interesting invariance rule of inverse problem solutions with respect to the temperature-dependent conductivity is identified and numerically demonstrated.


When learning how to play a strategy board game, one can measure the relative effectiveness of the learned policies by assessing how often a player wins and how easily these wins are scored. Experimental evidence also shows that when one of the competing players is trained by a sophisticated tutor, performance benefits also flow to the opponent. We present comprehensive experimental evidence that the level of tutor sophistication is best demonstrated by the improvement of the tutored player's opponent. This performance change is termed the pendulum effect, whose rationale we also trace to game theory.


In its activity, a company always has orientation on maximum profit or goal achievement. Nevertheless, the company must try maximally to realize it well using the possessed resources. One of the main determining factors in achieving company?s goal is the availability of work capital resource that has function to fund company?s operational activity. Capital resource is a utilizing form of work capital amounts, which is used by funding company?s activity directly, giving impact on company?s profitability. The purpose of this research is to review the policy of Tempe crispy small-industry owner in Malang City to manage work capital. Secondly, to analyze work capital management efficiency related to Tempe crispy small-industry profitability. For small industry, this research result is expected to be consideration material in making decision in accordance with work capital related to company?s profitability. The analysis result regarding to the policy of Tempe crispy small-industry owner in Malang City to manage work capital can be described as follow: owner, in cash management to fund operational activity during this time, not only uses own capital or cash, but also uses debt. It is done to close the expensed fund in company?s operational activity. In receivable account management, owner applies sale system in-cash and in-credit. Owner also gives some discount in order to improve sales volume, especially for purchase in cash and in great volume. There is some weaknesses in controlling receivable account, where the company do not make any contracts or give some conditionals to consumers, who buy in credit, and it is just using reliance system. In supply management, owner is not only depended on one raw-material supplier. It is to avoid the lack of raw-materials supply. While for the finished product management, owner conducts a precise packaging system, so its product won?t be broken easily. Based on the analysis result, hence it can be known that during this time the owner has conducted an efficient work capital management. Some suggestion can be submitted from this research result: it is expected that industry owner sets work capital-budgets and conduct some reviews regarding his/her policy on the applied receivable account during this time. It is expected that the owner implements just-in-time method as the control alternative on the stock. Keyword : Modal kerja, profitabilitas Link Terkait : http://skripsi.umm.ac.id/files/disk1/296/jiptummpp-gdl-s1-2008-indahpurwa-14773-PENDAHUL-N.pdf


funding provided by participating member commissions of the National Association of Regulatory Utility Commissioners (NARUC). The views and opinions of the authors do not necessarily state or reflect the views, opinions, or policies of the NRRI, the NARUC, or NARUC member commissions.


Application of seismic attribute in subtle traps exploration makes most of seismic information,and seismic attribute analysis is a key of application of attribute in subtle traps exploration.The new method for seismic attribute analysis colligates information of seismic,logs and geology by crossplot and broadcast and cluster with the methodology of science instead of analysis with handcraft and eyeballing.With the method,seismic attribute analysis plays an important role in subtle traps exploration.


A new cascade refrigeration cycle has been proposed,which can operate in two models with an internal heat exchanger employed in the low-temperature cycle to recycle the cooling.The corresponding refrigerator apparatus was been designed and built.The feasibility and performance of the cascade refrigeration cycle were investigated through experiments.Detailed suggestions were put forward to improve the system performance on the basis of experimental data,such as increasing the efficiency of regenerator,optimizing compression ratio,enhancing the heat-exchange of condenser,optimizing the cooling output by the evaporator,and adding a bypass between the condenser-evaporator's inlet and outlet.The COP of the improved cycle is enhanced, which showed the dual model cycle for cryogenic refrigerator is feasible and has a promising foreground.


Abstract With population aging, many people can expect to spend 30 or more years in old age. The five papers included in this symposium aim at shedding light on whether and how to make plans for old age, using data from the "Aging as Future" Project. First, Park and Hess used data spanning across adulthood from Germany, Hong Kong and the USA to examine how changes experienced in domains of functioning and the importance attached to these domains influenced preparations for old age. Next, de Paula Couto and Rothermund, examining Germans aged 40-90 years, pointed out that prescriptive age stereotypes might be the main drive for why people make preparations for age-related changes. The remaining three papers use qualitative data to qualify the above quantitative findings. Adamson and Ekerdt interviewed older Midwest US residents. They observed that SES greatly impacted how older adults perceived and made plans for their future. The final two papers examined how rural vs. urban contexts might affect preparations for future. Liou interviewed older adults in rural Tainan and found that their ideal old age was one about no future preparation, at least not about making plans for themselves (called "tranquil life"). Ho and colleagues, in contrast, found that for older Chinese residing in urban Hong Kong, not preparing for the future (called "time freeze") was negatively related to physical and psychological well-being. The symposium will end with an overall discussion on future research directions on whether and how to make plans for old age.


Black spruce is the most common tree species in Canada, dominating treed peatlands where they are usually stunted. We used 495 destructively sampled trees from 56 plots to develop allometric models of aboveground biomass by components (stem, branches, and needles) for small (<5 m tall) black spruce from peatlands in the Taiga Plains and Boreal Plains Ecozones of Western Canada, for which there were no specific models available of biomass by components. We used leave-one-plot-out cross-validation to assess transferability and compare our models with existing national and ecozone-specific equations. Our models predicted total tree biomass with better accuracy and less biased estimates than the national model (relative RMSE: 30% versus 35% national; relative bias: +1% versus –12% national). Similar results were obtained in other external datasets. Existing ecozone equations performed worse than either our models or the national ones. When we applied the models at the plot level to predict aboveground biomass density (Mg·ha−1), our models outperformed the national model again (relative RMSE: 15.9% versus 18.6% national, relative bias: +3.5% versus –13.6% national). These results indicate that at least for peatlands of Western Canada, our models provide better aboveground biomass estimates for small black spruce trees than existing models.


In this article, an overview of nonparametric item response theory methods for determining the dimensionality of item response data is provided. Four methods were considered: MSP, DETECT, HCA/CCPROX, and DIMTEST. First, the methods were compared theoretically. Second, a simulation study was done to compare the effectiveness of MSP, DETECT, and HCA/CCPROX using the default settings of each program in finding a simulated dimensional structure of a matrix of item response data. In several design cells, the methods that use covariances conditional on the latent trait (DETECT and HCA/CCPROX) were superior in finding the simulated structure to the method that used normed unconditional covariances (MSP). Third, the correctness of the decision of accepting or rejecting unidimensionality based on the statistics used in DETECT and DIMTEST was considered. This decision did not always reflect the true dimensionality of the item pool. Index terms: DETECT software and method, dimensionality of item response data, DIMTEST software and method, HCA/CCPROX software and method, MSP software and method, multidimensional item response data, nonparametric item response theory, unidimensional item response data.


This paper describes the evolutionary development of adaptive signal processing algorithms which utilize spatial and spectral information provided by a passive infrared sensor to enhance the detectability of targets in clutter. Key parameters affecting the performance of multi-spectral detection processors are identified and discussed. Adaptive filtering algorithms are presented which can achieve near-optimum detection performance with no prior knowledge of the target and background spectral properties.© (1990) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.


The invention relates to a radical polymerizable polyurethane composition. The polyurethane composition comprises polyurethane containing active olefinic bond and a reactive diluent. The polyurethane containing active olefinic bond is prepared from a component comprising (methyl) acrylate. The polyurethane composition has good operable time, relatively high heat distortion temperature and relatively low exothermic peak.


Sea surface salinity (SSS) is an important parameter of the physical marine environment and its variation has significant effects on the hydrodynamic environment in the South China Sea. With the developing of sea surface salinity retrieval technology based on SMOS data, intuitive SSS could be obtained. Study on the SSS could help better understand the role of salinity in ocean circulation and the global water cycle. In this paper, multi-dimensional analysis methods will be applied to study on the temporal and spatial variability pattern of sea surface salinity from 2014 to 2019 in South China Sea. In this paper, to reveal the temporal and spatial variability of SSS in South China Sea, time series analysis, geostatistical method and EOF decomposition algorithms were adopted. The purpose is studying on the temporal and spatial variability pattern of sea surface salinity from 2014 to 2019 in South China Sea.


The timetabling problem at universities is an NP-hard problem under multiple constraints and limited resources. Thus a technique that can handle constraints is needed to optimize the problem. This paper focuses on Particle Swarm Optimization (PSO) for finding optimal solutions to the problem of course Timetabling at a Punjabi University Patiala. PSO is a promising scheme for solving NP - hard problems due to its fast convergence and fewer parameter settings . There are two objectives in this. First provide a detailed introduction to the topic of timetabling, Particle Swarm Optimization their method and their variations. The second objective is to apply them to the problem of Course Timetabling. The proposed algorithm is tested using the timetabling data from Department of Computer Science, Punjabi University, Patiala.


The present invention relates to an optical reading apparatus, when the optical reading apparatus using a processing line image arrayed light receiving element linear image sensor to read, it is possible to prevent unintended image inversion. To this end, the present invention is an optical reading apparatus, comprising: an optical reading unit in a direction having a reading target transport direction of the recording medium S is orthogonal to a linear image sensor of a light receiving element, and the linear image sensor optically reads the conveyed recording medium, and the linear image sensor of each detection value of the light-receiving element read out sequentially from one end and an output; gate array, which is generated based on the detection value of the optical read unit reading output the image data is added in the read image data generated in the information about the relationship between the representation of the pixel arrangement order of the linear image sensor having a light receiving element of the read order of read image data, and means for transmitting the other; and a CPU .


OBJECTIVE To study the effect of different anesthetic methods on postoperative lung infections in the elderly patients undergoing selective abdominal surgery so as to provide effective statistics for the best clinical anesthesia method.METHODS A total of one hundred and twenty elderly patients,who underwent the selective abdominal surgery from Mar 2011to Mar 2012,were enrolled in the study.The patients were divided randomly into three groups,including the complete intravenous anesthesia group(group A),the inhaling anesthesia group(group B),and the epidural block combined with general anesthesia group(group C),with 40cases in each;the difference in the indicators between the three groups was compared.RESULTS The incidence of postoperative pulmonary infections was 22.50% in the group A,25.00% in the group B,and 5.00% in the group C;the recovery time was(15.86±7.52) min in the group A,(16.41±8.03) min in the group B,and(8.76±3.92) min in the group C;the extubation time was(21.73±10.97) min in the group A,(23.55±11.46) min in the group B,and(13.28±6.81) min in the group C,the difference in the incidence of pulmonary infections,the recovery time,or extubation time between the three groups was statistically significant(P0.05),the incidence of postoperative pulmonary infections was significantly less in the group C than in the group A or the group B,the difference was statistically significant(P0.05).The level of CD 4 + or CD 4 + / CD 8 + decreased more significantly 6hours within the operation or 1day or 3days after the operation than before the anesthesia,the difference was statistically significant(P0.05);as compared with the group A and the group B,the level of CD 4 + or CD 4 + / CD 8 + decreased slightly in the group C 3days after the operation(P0.05).CONCLUSIONFor the elderly patients undergoing the open abdominal surgery,the epidural block combined with general anesthesia is conducive to the early extubation with the slight immunosuppression and the lower incidence of postoperative lung infections.


Taking as a case public outcry in the Netherlands in 2008 over criticism of a black mask as being racist, this paper argues for recognizing the ambiguity of this ritual symbol.


Background: The aim of this study was to measure 137 Cs levels in soil and brick samples to set the baseline data and an indicator of fallout radioacƟvity for this part of the world. This study will help to probe, if there is any health threat posed by 137 Cs exposure to the residents of the area. Materials and Methods: Twenty five samples of soil and 6 samples of bricks were collected from different locaƟons of Mirpur of Azad Kashmir. A P‐type HPGe detector was used to measure gamma spectra of samples. Results: Results showed that for soil samples acƟvity concentraƟon range from 0.076±0.071 to 2.94±0.17 Bq.Kg ‐1 with average value of 1.39±0.17 Bq.Kg ‐1 . Similarly acƟvity concentraƟon of 137 Cs in Brick samples range from 0.22±0.09 BqKg ‐1 to


As one of the most prominent writers in contemporary American literature, Don Delillo in his works has covered almost all the important American social issues since the Second World War and exhibited in them a kaleidoscopic society of "magic and dread". Focusing on Underworld, this essay selectively studies the illusiveness of an American identity, which is the premise of the logic of Us versus Them between America and the Soviet Union during the Cold War era; it also exposes the profound relationship between garbage that rapidly increases and the consumer society. The complexity and uncertainty of these questions leave much for further study in this area.


The university students' pressure has induced Mental Confusion.It has mingled Ideological and Psychological Problems.Ideological and Psychological Problems are very important for our life.Ideological is similar to Psychological Problems.In this paper,the author through the elaboration on the Psychological Problems of students that can not be confused with the Ideological Problems,and at the same time,the Ideological Problems of students that can as well as be not mistaken for the Psychological Problems.So this passage has discussed that the university students attach importance to Ideological Education Work and Mental Health Problems.


For the research of forecasting numbers of tourist in tourism destination,author takes two steps,first,constructs forecasting theory model which obeyed the rules of tourism law,then uses the corresponding mathematic theories to dispose tourists' data and forecasts the future tendency in tourism destination.In this study,author imports the concepts of velocity and acceleration and other relevant variables to construct the model for endowing the constant terms with tourism meanings,gives the conditions for using the model.Combine with the theory of tourism area lifecycle,the model can be used to forecast the max numbers and time in tourism area.


In the world today, qualities of lives among humans are decreasing at a rapid stage. This is caused by our never-ending wants and needs. And in order to satisfy our greed, our mother-earth are being destroyed at a rapid stage. More natural resources have to be harvested and of course more pollutions are being created inevitably. With this rising concerns, organizations around the world are creating awareness of this phenomenon as part of their corporate social responsibilities. The real estate industry too, is on this trends. No doubt that this industry contributed most to the environmental impacts. They can cause both direct and indirect impacts on the environment. Even the first step in planning, developing to even managing the estates cause an environmental impacts. In recent years, both developers and consumers are being aware of these negative circumstances, in response to this, they are now more concerned when buying and/or developing the real estates. This study have emphasized on the relationships between purchasing attitudes and intentions to purchase green condominiums on Generation Y. Why Gen Y? Research conducted found that this generation of people are more aware of this environmental issues and willing to act accordingly. This research is conducted based on the quantitative method and the questionnaires used to reach the respondents will be online-administered. The target group will be between 18-35 years old and live in Bangkok. After filtering the questionnaire collected, 220 sets were used in analyzing. There are 3 steps in the process when analyzing the data. The descriptive statistic were used on the first step to obtain the demographic characteristics of the respondents. While on the second and third steps, regressions and two-way Anova tests were employed respectively. The results obtained from this study found that "intentions to purchase" on green Condominium on generation Y has a positive relationship on "purchase attitude". While "environmental knowledge", "Perceived Benefits", "Environment Concern", "health conscious" and "subjective norms" also have a relationship with "purchase attitude" and direct effect with "intention to purchase".


In externally pressurized gas-lubricated circurlar thrust bearings, the occurrence of depression in the pressure profile is observed under some working conditions. Following the previous paper on the theoretical investigation of pressure depression, this paper investigates theoretically the pressure distribution in externally pressurized circular thrust gas bearings with a circular recess by assuming the generation of a normal shock wave in the bearing recess. Good quantitative agreement is found between the analytical results and available experimental data except the case of small bearing clearance height or deep recess. In order to prevent the pressure depression just after the gas supply hole, it is effective to provide a round or tapered chamfer at the entrance edge of the hole to the bearing clearance or to make the recess tapered doubly. Through these alternations, the shape of pressure distribution becomes flatter so that the load capacity can increase remarkably.


Introduction: Haemangiomas are rapidly growing vascular abnormalities that are benign in nature and often manifest in the neonatal period or during childhood. It is most commonly seen in the head and neck region (60-70%). It is rarely found in the oral cavity and occurrence in the tongue is even rarer. Haemangiomas in the oral cavity are always of clinical importance and require an appropriate treatment. Case report: A 26-year-old male patient reported to our unit with history of swelling on the left lateral surface of tongue and difficulty in swallowing and breathing since 3 months. The patient was diagnosed to have vascular lesion after FNAC and MRI report. Patient was treated by embolisation of left lingual artery followed by surgical excision. Post op biopsy report showed the features of cavernous haemangioma. Conclusion: Haemangioma continues to be used as a clinical and pathological description for many different types of vascular anomalies. The treatment modality should be planned according to the diagnosis and prognosis of the haemangioma.


Objective To research the preparation and quality control of galactophore Ⅰ decoction,and to observe the therapeutic effect on galactophore hyperplasia.Methods The shuiti's concentration is adopted to manufacture galactophoreⅠdecoction.The quality control was made through the preparation's character,pH value,comparative concentration,distinguish,animalcule limit and stability.Results The preparation method and quality standard of the decoction was constituted,and its therapeutic effect was distinct.Conclusion The preparation technique is good,and the decoction has therapeutic effect on galactophore hyperplasia.


This paper takes a systemic perspective on the design process of apartment buildings. By including the participation of different and dealing with several variables constituting a set of parts in interaction, such processes could be approximate with the notion of complex systems. It is understood that changes in the forms of organization of these design processes may favor the introduction of innovations, both for the process itself and for its products and may result in projects with better architectural quality.


Through a comprehensive study of the results of dynamic monitoring exploration for seawater in Laizhou Bay by AMT method and other original data,the authors acquired further understanding of the present situation of seawater invasion inside the study-area.Moreover,the authors divided the interface zones between the salt and the fresh water,which resulted in favorable effects of environmental geology.The results indicate that the AMT(EH-4) method is effective in determining the interfaces between the salt and the fresh water,delineating the infection tunnel of seawater and observing the regularity of interface migration.


The invention discloses an interventional anti-infective water-based adhesive which comprises the following components in parts by weight: 100 parts of n-octyl a-cyanoacrylate, 10-15 parts of polymethacrylate, 4-10 parts of tetracycline, 2-6 parts of secnidazole, 0.2-0.5 part of hydroquinone and 0.05-0.2 part of sulfur dioxide. The interventional anti-infective water-based adhesive disclosed by the invention enables the human body tissues to be easy for binding in an anaerobic and solvent environment, has counter force against anaerobes, can effectively relieve the infection of the human body tissues in or after operation, and has the function of diminishing inflammation, thereby ensuring the binding effect of the human body tissues.


Background Overweight and obesity in childhood is associated with physical, psychological and social consequences. Physical inactivity is regarded as one of the main factors that have contributed t ...


The changing rules of the landscape elements and their distribution in east Xuzhou coal mining area are analyzed by means of remote sensing images obtained in 1979, 1987 and 2001. From 1987 to 2001, the land area for urbanization and industrial purpose got expanded; the intensity of construction was becoming higher and higher; the waterlogged area resulted from mining subsidence increased; and the lands covered by plants decreased. About 9.55% of the farmland was transformed into construction land and 5.15% into waterlogged land. About 5.25% of the construction land was converted into farmlands by reclamation, being mainly derilict mining sites; and 3.21% into waterlogged land, being mainly located near mining industrial square. Some 14.86% of the subsided waterlogged land was reclaimed into farmland, being mainly located near the edge of the subsiding basin with less subsidence; and 10.88% into construction land, being mainly located near Hanqiao and Quantai coal mining industrial squares. Generally speaking, the area of farmland decreased 13.04%, construction land increased 37.62% and waterlogged land resulted from mining subsidence increased 137.62%. So, according to the land condition, it is very important to reclaim and reuse subsided waterlogged land effectively for different purposes, such as eco-agriculture, aquaculture, forestry, animal husbandry and processing industry.


The article deals with the planning and implementation of material transport. The quantity of transported material increases year after year. The article focuses on the issue of responsiveness to the crisis situation at the planning stage or during the transport process. Crisis or emergencies are common every day in road transport. Solutions and opportunities to respond to these events are inadequate. The proposed tool makes a static planning a dynamically controlled transport process.


Exact knowledge of the crystal structure of drugs and lead compounds plays a significant role in the fields of crystal engineering, docking, computational modeling (drug–receptor interactions), and rational design of potent drugs in pharmaceutical chemistry. The succinic acid cocrystal of the systemic antifungal drug, itraconazole, reported by Remenar et al. (J. Am. Chem. Soc.2003, 125, 8456–8457) (CSD: IKEQEU), represents one of the classical examples displaying a molecular fitting mechanism in the solid state. In this work, we disclose the X-ray single-crystal structure of the cis-itraconazole–succinic acid (2:1) cocrystal and found that it differs slightly from the previously reported structure by the location of the elements (C, H, and N) in the 1,2,4-triazol-5-one ring. By making use of the new solid-state structure, we have also applied an enhanced disorder model, which, in turn, uncovered the intriguing halogen bond (XB) interactions (0.86 × van der Waals distance of C–Cl···N), which were previousl...


The use of operational definitions is necessary to educational research of the "normal" kind, but can easily lead to philosophical naiveté and the misleading reporting of results. Robert Ennis's recommendations on the logical form of operational definitions are supported, as a means of avoiding constricting research dogmas, but a case is also made for reminding research trainees of the richness of many educational concepts borrowed from ordinary usage, and of what Polanyi calls the fruitfulness of concepts that are not completely specifiable.


LoRa has established itself as one of the leading technologies within evolving low power wide area networks. In the patented LoRa modulation, a linearly increasing basis chirp signal spans the LoRa bandwidth. Cyclic shifts of this basis chirp signal create a multidimensional space for the orthogonal signaling of nonbinary LoRa symbols. The number of bits per LoRa symbol as well as the symbol rate depend on an applied spreading factor (SF) that could vary between 7 and 12. In this paper, interleaved chirp spreading LoRa (ICS-LoRa) is proposed as a physical layer-inspired approach to enhance data rates of the capacity-limited LoRa networks. In ICS-LoRa, interleaved versions of the nominal LoRa chirp signals constitute a new multidimensional space with the purpose of adding one extra bit within each transmitted ICS-LoRa symbol. The proposed interleaving pattern of ICS-LoRa maintains the same communication robustness of nominal LoRa. The ICS interleaving pattern is also designed to simplify implementation where both ICS-LoRa modulation and demodulation can share the same ICS-interleaver block. An accurate approximation for BER performance of the proposed ICS-LoRa is derived in order to evaluate the underlying reception sensitivities. It is shown that the 14% capacity gain of ICS-LoRa with an SF of 7 is associated with a sensitivity loss at the scale of only 0.8 dB. On the other hand, ICS-LoRa achieves more than 8% in capacity gain with virtually no impact on sensitivity performance when using an SF of 12 that governs the maximum coverage range.


Excellent legal talent training plan brought development opportunities for legal education.The employment difficulty of law major in which the principal problem is the shortage training of professional skills,not the structure of maladjustment of supply and demand. Nowadays,the main steps of practical teaching are legal advice,court hearing,moot court,legal clinic and graduation field trip. It has an even chance of success. Bachelor of law should guide for quality-oriented education and enhance practical teaching; Juris Master should guide for vocational education and strengthen career skills training; pre-employment training should guide for vocational adaptability and take competitive training seriously.


Shelf-derived limestone boulders in debris flows of the Cow Head Group, western Newfoundland, have yielded rich mid- to Upper Cambrian trilobite faunas. The agnostoid component of Marjuman boulders consists of 23 species assigned to 11 genera; Kormagnostus boltoni and Kormagnostus? copelandi are new. Cladistic parsimony analysis of the Ptychagnostidae Kobayashi reduces this family to 3 genera: Ptychagnostus Jaekel, Pseudophalacroma Pokrovskaya and Lejopyge Hawle and Corda; Ptychagnostus includes three non-obligate subgenera: P. (Ptychagnostus) (= Tomagnostus Howell); P. (Goniagnostus) Howell and P. (Aotagnostus) öpik (= Myrmecomimus öpik). Correlation with zonations established in northern Canada and Utah indicates that the Cow Head Group includes a nearly complete sequence of agnostoid faunas from the mid-Cambrian Ptychagnostus gibbus Zone to the Upper Marjuman Cedaria brevifrons Zone.


the limitations of the TCA count method according to the current normative and methodological standards. A scoping review was carried out for TCA count methods for AE, including experimental studies and technical notes in the PubMed/Medline, Scopus, Web of Science (WoS) and Embase databases. The terms "estimation", "age" and "cementum" were used, with a complementary manual search in Google Scholar. Reviews, studies in archaeological collections, radiological studies and letters to the editor were excluded. The search yielded a total of 273 articles, selecting 27 of them that met the inclusion criteria. Most of the studies were published in Asia, particularly India (n=21). Only 6 articles declared the total number of individuals, types of teeth, and histological sections, with the premolar being the most studied. Only two articles evaluated the quality of the sample to be analyzed through the legibility of the cuts obtained. The most widely used test to assess the precision of the method was the Pearson correlation coefficient (n=21). These findings expose the high heterogeneity reported in EE methodologies by counting TCA, so there is still no standardized process that covers in all its stages and delivers reliable results following current legal standards for scientific evidence. More control of the detected technical limitations will increase the value as evidence in a legal or forensic identification context.


The present invention discloses a method for preparing an antimicrobial and catheter, a medical device field and its preparation method, the catheter comprising an antimicrobial catheter, said catheter further comprising a surface disposed antibacterial layer, the antimicrobial wrapping layer is composed of aggregate of nano metal particles of polymer, nano-sized metal is a metal having antimicrobial properties. Preparation method sequentially comprising the steps of: preparing nano metal solution; solution was added to the polymer solution and the nano metal, metal nano-modified polymer-wrapped or preparing nano metal - polymer composite, polymer-wrapped nano metal particles to obtain a solution; the polymer solution was wrapped nano metal particles attached to the surface of the catheter, i.e. washed and dried to give antimicrobial catheter. The present invention product is a simple, low cost, stable and effective long-lasting antimicrobial effect may be controlled antibacterial catheter. Preparation process of the invention, which method is simple, low cost, durable and stable final product effective antibacterial effect can be controlled.


http://ajs.sagepub.com/content/40/6/1289 The online version of this article can be found at: DOI: 10.1177/0363546512441585 2012 40: 1289 originally published online April 5, 2012 Am J Sports Med Nayana Joshi, Mercè Reverte-Vinaixa, Eugenio Wenceslao Díaz-Ferreiro and Rosa Domínguez-Oronoz Young Patients: Magnetic Resonance Imaging and Clinical Evaluation Synthetic Resorbable Scaffolds for the Treatment of Isolated Patellofemoral Cartilage Defects in


Study shows social cultural and economic background of 500 riral pregnant mothers. Findings about pattern of intranatal care and puerperium are presented.


To study the possibility of cascade refrigeration system using R744 running below R744 triple point temperature (216.58 K),the binary mixtures of R744 and nature working fluid(such as R170 and R1150) were introduced to reduce R744 triple point temperature and substitute for R13.The models of solid-liquid(equilibrium) and vapor-liquid equilibrium were proposed and mixture ratio which can make R744 not produce crystal blow its triple point temperature was found.The low-temperature cycle performance of cascade refrigeration system using mixture of R744/R170 and R744/R1150 at given component was simulated.From the calculation results at the same condensing and evaporating temperature,one of the mixtures of R744/R170 and R13 have the same compressor ratio and close pressure curve.Unit volume refrigeration capacity,unit mass refrigeration capacity and coefficient of performance(COP) of them also have little discrepancy.Then the mixture has close cycle performance to R13,and is a good alternative substitute for R13.


Two d10 complexes [Cd(abt)I2(H2O)] (1) and [Ag2(abt)2]·2(CF3SO3) (2), (abt = 4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole) have been obtained and characterized by IR, elemental analysis, and X-ray diffraction single-crystal analysis. Complex 1 is mononuclear and Cd(II) center is five coordinated, while complex 2 possesses a dinuclear structure with coordination number 4 for Ag(I) center. Solid-state fluorescence spectra of 1, 2, and abt were investigated at room temperature.


A new asterosaponin named novaeguinoside A, along with a known saponin, asteronyl pentaglycoside sulfate, was isolated from the starfish Culcita novaeguineae. The new compound was identified to be sodium 6α-O- { β-D-fucopyranosyl-(1→2)-β-D-fucopyranosyl-(1→4)-[β-Dquinovopyranosy1-(1→2)]-β-D-xylopyranosy1-(1→3)-β-D-quinovopyranosy1}-5α-pregn-9(11)-en-20-one-3β-yl-sulfate by extensive spectral analysis and chemical evidence.


Optimal nutrient delivery is one way to improve the quality and quantity of crop production. This is because the crops needs for nutrient is quite high, while the soil capacity in providing nutrients is limited. In addition to fertilization, nutrients can be given in the form of added organic material or planted as cover crop. The research took place from April to August 2016 in Bandar Pinang, Bandar Sumatera Indonesia Ltd. (SIPEF Group) plantation, with survey method. Soil samples were taken based on: Topography (flat and slope 15-30%), cover crop (with or without Mucuna bracteata) and plant age (seedling periods 1, 2 and 3). The soil sample is taken composite by zig zag method. The observed parameters were organic matter, N total, soil texture, bulk density and infiltration rate. Mucuna bracteata planting increased the contain of soil organic matter by 30.43% in flat area and 53.33% in hilly area, amount of N total soil by 27.27% in flat area and 7.69% at hilly area, bulk density 3.73 % In flat area and 0.41% in hilly area, soil infiltration by 48.88% with sandy clay dominant soil texture.


Gilyarovsky, speaking about the "form, content and course in psychosis" ("Council, not vropat., Psychiatr. And psychogyny." in psychosis and to a certain extent determines the form and content of psychosis.


Childhood medicalization: productions of meaning on the discourse of health professionals. This study aimed to understand which senses are attributed to the medicalization of care recommended to mental health in childhood by professionals who serve children and adolescents in health services. For this investigation, the methodology it was used the Discourse Analysis, thus giving visibility to the productions of meaning of each patient. The aim of this study was to understand the reasons that emerge in the speech of these professionals, when questioned, through semi-structured interviews, about the ways of care destined for childhood in relation to medicine's treatment. The findings show that the medications are pointed out as the first form of care intended for childhood. The logic that was found in this research points to the use of medicines as a means to supply the absence of one of the family figures, as well as access to information that would call into check for consumption, the pharmaceutical industry and mental health.


A new type of formal specification language ( PD_ Cal) is introduced,which is of good capacities of description and abundant types.Type- checking the theorem proof represented by the proposed calculus,we can find outwhethertheproof isthe rightone ofthe given theorem.Underthe basis of the thought,we design and implementthe PD_ Cal Theorem Proof Checker.


Roller compacted concrete road pavement more routine normal concrete with compressive,flexural,impact resistance,fatigue resistance and so on significant performance advantages.It relied on Cangxi county,Sichuan province rural highway pavement roller compacted concrete scientific research project,research on the basic performance of the pavement roller compacted concrete,analyzing factors that affect rural highway pavement roller compacted concrete workability,raw material control,and on this basis put forward rural highway pavement roller compacted concrete mixing proportion range,on this basis,the research on the dosage of fly ash pavement influence of physical and mechanical properties of roller compacted concrete.


By questioning the feasibility of the explanations of "didn't need to do" and "needn't have done" commonly used in grammar books and textbooks,the authors discuss the meanings and features of the full verb and the modal verb and thereby come up with a more acceptable explanation of the two structures.


Using the non-memory property of two-Parameter Exponential Distribution functions,the paper gives the relation about survival probability Ri in time ti.Basing on the relation we obtain the BAYES estimations about Ri in time Ti and estimate the distribution's parameter.


We prove uniqueness of equilibrium states for subshifts corresponding to intermediate beta transformations with $\beta > 2$ having the property that the orbit of 0 is bounded away from 1.


This paper presents a formal definition of the operation quality of factors that play a significant role in operations. The focus is on factors of symbolic nature, such as data, information, and rules of reasoning and/or proceeding. The definition includes a philosophical perspective of quality, communications, decision-making, implementing, and acting, which are always affected by explicit or implicit purposes. Purpose and circumstances pervade all aspects of quality assessment. The emphasis is on routine operations and assessment of quality from the operations-management perspective. Strategic management of operations requires a different perspective and a separate inquiry.


Human sacrifices were a ritual practice during the expansion of the Inka Empire. Nevertheless, the homeland of the victims has never been clearly determined. A mummy recently found in a mediterranean environment in the Andes of Argentina provides a unique opportunity to shed some light on the matter. His clothing and funerary trousseau give no evidence regarding his ethnic filiation, geographic origin, nor whether he belonged to the local population or to the Inka elite. Therefore, a decodification of his geographic origin was attempted. This was done through the reconstruction of his palaeodiet: A diet based on continental products would indicate a local origin whereas one including marine food would suggest ties with the Pacific littoral and, indirectly, a foreign origin. Carbon, nitrogen, and sulfur isotope ratios of the mummy's bone collagen and hair were compared with values from archaeological populations from littoral and altiplanic environments of South America. The carbon and nitrogen isotopic values of bone collagen were ambiguous tracers, indicating either a continental diet with a high percentage of maize, one including a certain amount of marine products, or a combination of both. The carbon and sulfur isotopic values of hair were conclusive, indicating a clear continental origin of the diet, at least during the period of a year and a half before death. © 1999 John Wiley & Sons, Inc.


With the rapid development of China's logistics,logistics enterprises are emerging in large numbers and they are very different in business type,scale and quality of service.Currently warehouse logistics enterprise generally lags behind,job division is not clear yet;warehouse employees are mostly skilled workers,business improvement should be combined with the practice;vocational college students basing themselves upon warehouse work should depend on key skills.


Abstract : The report presents a review of the various methods available for the demodulation of the angle-modulated sinusoids. Three major sections are contained in this report: Demodulation of Analog Angle-Modulated Signals (Conventional FM Discriminators) (Phase-Locked Demodulation), Special Feedback and Feedforward Demodulators for Analog Modulated Signals, and Digital Signalling. In Section 2 conventional discriminator detection is discussed along with various forms of phase-locked demodulation. These areas have received the greatest attention in the literature and consequently are given the greatestspace in this report. Section 3 describes a wide variety of special feedback and feedforward demodulation methods for angle-modulated signals. The frequency-feedback demodulator is considered here along with the numerous forms of 'modified' phase-locked loops. Feedforward demodulation methods are also discussed. Nonlinear post-detection filtering, described in greater detail in Vol. I (AD-639 787), is reviewed here for completeness. Various binary and M-ary methods of digital signalling are reviewed in Section 4. Optimum and near-optimum detection methods are described for: PCM-FM, FSK, PSK, DPSK, MPSK, M-ary coded PSK, and MFSK. (Author)


Damage growth and tolerance are major drivers to determine the frequency and cost of inspections and the lifespan of structures. The detection and identification of damages together with the assessment of structural integrity by non-destructive evaluation (NDE) methods is of fundamental importance and requires analysis towards effective solutions. Among the numerous NDE techniques, ultrasonic guided waves (UGWs) are acknowledged as one of the most effective tools to identify damage in composite structures, offering promising results and research opportunities for their nonattenuative nature and complex behavior. Generating from a well-defined interaction of ultrasonic waves with bounded media, UGWs become "naturally" supported from the structure itself and show high susceptibility to interference on a propagation path (i.e. damage or boundary) providing many advantages as large-area coverage, crosssectional area inspection, sensitivity to multiple defects and cost-effectiveness. The implementation and interpretation of UGWs, though, are very challenging, due to the infinite set of mode-frequency combinations to probe structures with. The propagation of UGWs into composite materials (multilayered, anisotropic), aircraft geometries (thin uniquely shaped components, i.e. curved skin, stiffeners, etc.) and interaction with composite impact damage (3D, highly heterogenous, load-structure dependent) add layers of complexity, as wavemode conversion and coupling, and nonanalytical solutions. More studies are needed to advance knowledge in UGWs interaction with specific composite damage modes to fully exploit the potential of this advantageous yet complex inspecting modality. Building on the experimental results of UGWs inspection by transfer function extraction in damaged aircraft panels, this work focuses on the analysis of UGWs measurements to identify impact damage signatures in a variety of impact damage energy levels and on two panel locations.


Studies of sound reception in aquatic animals are often complicated by the problem of generating a suitable acoustic stimulus at low frequencies underwater. In this study, active and passive control techniques were used to generate a traveling acoustic wave inside a water‐filled acrylic tube, at pure‐tone frequencies from 10 to 800 Hz. The compliant walls of the tube reduced the wavelength and increased attenuation, both of which helped to reduce the amplitude of any reflected waves. Above 400 Hz, a traveling wave was present without any active control. Below 400 Hz, a secondary source was used to actively absorb sound at the tube end. The active control system consisted of two hydrophones, two sound projectors, and a personal computer with digital signal processing hardware. A simple pattern search algorithm was used to adjust the secondary source amplitude and phase in order to attain the desired acoustic impedance at the test location. This technique seems well suited for underwater sound tests on fish...


Cabbage and cauliflower are grown extensively in Himachal Pradesh during winter in the mid-hill regions. The cultivation is hindered by many insect species, among which the cabbage white butterfly, Pieris brassicae (L.) is the most devastating one. The larvae are gregarious and feed voraciously. The nutritional quality of leaves as well as ecological conditions have impact on regulation over the quantum of food ingested, digested and digestibility of food in insects. In order to study the host plant relationship and feeding behavior, a study was conducted on the food (cabbage and cauliflower) utilization by the larvae of P. brassicae.


SUMMARY Despite limited preparation through formal and non-formal education, local people throughout the world are engaged in the common work of building healthier communities. Some core competencies-including community assessment, planning, mobilization, and evaluation-are needed to address the variety of issues that matter to local communities. This report describes an Internet-based support system for community work known as the Community Tool Box (CTB) [http://ctb.lsi.ukans.edu/]. We examine the idea and origins of the CTB and its core content, access features, and applications. We review evidence for its use, implementation and dissemination strategies, and discuss core values that guide this internet-based work.


We present the results of measurements of 26Al and 10Be produced in situ in 12 samples of Libyan Desert Glass by cosmic rays during the last ten million years. Based on the variability of the concentrations of 10Be and of the 26Al/10Be ratios we measured, we conclude that individual fragments of glass have experienced different exposure histories, implying several major redistributions of the glass within the past 106 years. The 26Al and 10Be concentrations are inconsistent with the theoretical estimates of the rates of in situ production. We estimate minimum production rates of 70 atoms g-1 yr-1 and 10 atoms g-1 yr-1 for 26Al and 10Be, respectively, produced in quartz at sea level between 60–90° latitude. Despite the present uncertainty in the rates of production, we feel that these results show clearly the effectiveness of in situ produced 26Al and 10Be in studying earth-surface processes.


Rice is one of the most important food crops, and the stability of its yield is crucial to national food security. Rice plant counting becomes critical in fine agriculture research and is closely related to rice yield. In this paper, we proposed a new multi-scale fusion based rice counting method (RPCNet), which consists of one feature extractor frontend and two feature decoder modules namely Density Map Estimator (DME) and Plant Object Recognizer (POR). Fineloss is introduced into DME to improve the network's ability to separate adherent plants. To verify the validity of our method, we conducted experiments on a high-throughput rice plant image dataset. Experiment results show that the MAE and RMSE of the proposed RPCNet are 2.6 and 3.4 respectively, which outperforms states-of-the-art methods. Results suggest that RPCNet can accurately and efficiently estimate the number of rice plants and replace traditional manual counting.


For EEG-based drowsiness recognition, it is desirable to use subject-independent recognition since conducting calibration on each subject is time-consuming. In this paper, we propose a novel Convolutional Neural Network (CNN)-Long Short-Term Memory (LSTM) model for subject-independent drowsiness recognition from single-channel EEG signals. Different from existing deep learning models that are mostly treated as black-box classifiers, the proposed model can "explain" its decisions for each input sample by revealing which parts of the sample contain important features identified by the model for classification. This is achieved by a visualization technique by taking advantage of the hidden states output by the LSTM layer. Results show that the model achieves an average accuracy of 72.97% on 11 subjects for leave-one-out subject-independent drowsiness recognition on a public dataset, which is higher than the conventional baseline methods of 55.42%-69.27%, and state-of-the-art deep learning methods. Visualization results show that the model has discovered meaningful patterns of EEG signals related to different mental states across different subjects.


Air-blown integrated gasification combined cycle technology can achieve high efficiencies compared with the more conventional oxygen-blown IGCC and also with Japan's current fleet of ultrasupercritical pulverised coal plants. This is the main reason why the Japanese are pursuing air-blown IGCC, with operation of a 250 MWe demonstration plant due to start in 2007.


We propose a new analysis technique for characterizing molecular interactions that combines an energy decomposition scheme, such as the Kitaura–Morokuma decomposition method, with energy density analysis, which partitions the total energy of the system into atomic contributions. The combined scheme, termed Interaction‐EDA, enables us to estimate the local contribution of interaction energy components, such as electrostatic, exchange, polarization, and charge transfer. The evaluation of the local interaction energy is rather important in large systems. For a numerical assessment, the Interaction‐EDA method is applied to the process of CO adsorption on Si(100) − (2 × 1) surface. © 2004 Wiley Periodicals, Inc. J Comput Chem 25: 1882–1887, 2004


Coercing new programmers to adopt disciplined development practices such as thorough unit testing is a challenging endeavor. Test-driven development (TDD) has been proposed as a solution to improve...


Experimental equipments are less in high education school and we can't perform an experiment remotely by an exist ing simulator.To solve these problems,we first propose the plan of implementing a remote virtual network lab by Cisco IOU and give a detailed description of the key technology in its realization.Various universities can construct the lab of his own by using these technologies.The experimental teaching will not be limited by amount of equipments,time and space.The teaching effect will be improved significantly.


The utility model discloses a far infrared sanitation healthcare cap which consists of phosphor powder, a ring-shaped plastic pipe, a healthcare layer, a brim, an upper surface layer, a moisture-proof breathable fabric layer, a nanometer far infrared fiber layer, an all natural cotton layer and a zipper, wherein the far infrared sanitation healthcare cap is provided with a cap body which has a double-layer structure; the cap body is connected with the brim; the ring-shaped plastic pipe is arranged on the brim; a cavity which is capable of storing the phosphor powder is arranged in the ring-shaped plastic pipe; the zipper is aligned and arranged on the upper surface layer of the cap body; the health layer which consists of the moisture-proof breathable fabric layer, the nanometer far infrared fiber layer and the all natural cotton layer from the top down can be arranged in the cap body; and the three layers are sewed into a whole. The healthcare layer which integrates the three layers is arranged in the cap body, so that double effects of safety and healthcare are provided when sanitation workers sweep the roads in autumn.


Geometric phases of optically driven atomic wave functions were measured using photon echo technique in a two-level atomic system. Geometric manipulations of the atomic quantum states will be discussed in the context of quantum computing


In his groundbreaking essay, 'Away from a definition of antisemitism', the historian David Engel points out that the term anti-Semitism was first coined in the late nineteenth century. This observation is not novel but, importantly, Engel encourages his readers to take some new steps. He suggests we acknowledge the contingent character of a concept - antisemitism - that is generally assumed to provide a mirror on the world rather than, as he argues, a construction and representation of it. The present essay takes Engel's insight in a different direction. For Engel's emphasis on the contingent origins and meanings of the concept of anti-Semitism suggests we stand in need of a history of the term. Put another way, we can ask whether it is really the case, as Engel seems to suggest, that the meanings of antisemitism were fixed in the 1890s and have not changed since. Focusing largely on the history of Great Britain, this essay explores this question by examining successive iterations of the concept of antisemitism alongside the history of the more recent concept of Islamophobia.


Mitochondria supply intracellular energy requirements during exercise. Specific mitochondrial haplogroups and mitochondrial genetic variants have been associated with athletic performance, and exercise responses. However, these associations were discovered using underpowered, candidate gene approaches, and consequently have not been replicated. Here, we used whole-mitochondrial genome sequencing, in conjunction with high-throughput genotyping arrays, to discover novel genetic variants associated with exercise responses in the Gene SMART (Skeletal Muscle Adaptive Response to Training) cohort (n=62 completed). We performed a Principal Component Analysis of cohort aerobic fitness measures to build composite traits and test for variants associated with exercise outcomes. None of the mitochondrial genetic variants but nine nuclear encoded variants in eight separate genes were found to be associated with exercise responses (FDR<0.05) (rs11061368: DIABLO, rs113400963: FAM185A, rs6062129 and rs6121949: MTG2, rs7231304: AFG3L2, rs2041840: NDUFAF7, rs7085433: TIMM23, rs1063271: SPTLC2, rs2275273: ALDH18A1). Additionally, we outline potential mechanisms by which these variants may be contributing to exercise phenotypes. Our data suggest novel nuclear-encoded SNPs and mitochondrial pathways associated with exercise response phenotypes. Future studies should focus on validating these variants across different cohorts and ethnicities. AUTHOR SUMMARY Previous exercise genetic studies contain many flaws that impede the growth in knowledge surrounding change in exercise outcomes. In particular, exercise studies looking at mtDNA variants have looked at very small portions of the mitochondrial genome. Mitochondria are the 'power house' of the cell and therefore understanding the mitochondrial genetics behind adaptations to training can help us fill knowledge gaps in current research. Here, we utilised a new mitochondrial genetic sequencing technique to examine all mitochondrial and mitochondrial related genetic variations. We have shown that there were no mitochondrial specific variants that influenced exercise training however there were 9 related variants that were significantly associated with exercise phenotypes. Additionally, we have shown that building composite traits increased the significance of our association testing and lead to novel findings. We will be able to understand why response to training is so varied and increase the effectiveness of exercise training on a host of metabolic disorders.


A system and method for controlling an instrumentation system, wherein the present invention includes an improved instrument driver software architecture. The instrument driver software architecture of the present invention provides a number of features, including instrument interchangeability, i.e., the use of interchangeable virtual instruments or interchangeable instrument drivers, improved performance, an improved attribute model, improved range checking, and improved simulation features, among others.


Purpose : The main objective was to research the elements and dimensions of university sustainability and to provide a comprehensive conceptual model for the realization of a sustainable university in the Iranian higher education system and to compare the approach of public and non-governmental universities. Methodology : The research approach was applied in terms of purpose and in terms of data collection method was descriptive-correlational. It was mixed in terms of qualitative and quantitative. In the qualitative section, the components of sustainable university were identified through semi-structured interviews with 17 higher education experts and policymakers selected through purposive sampling. Content analysis method was used for data analysis by inductive method. The research method was quantitative descriptive-survey. The research instrument was a researcher-made questionnaire consisting of 8 subscales and its content extracted from qualitative data. The population consisted of 322 faculty members of public and non-governmental universities selected by Cochran formula. The construct validity of the instrument was confirmed by experts and its reliability was calculated by Cronbach's alpha. Data were analyzed using SPSS and AMOS software. Findings : The results of the data analysis in the coding process finally included 8 main categories of pedagogy elements and dimensions in the processes of learning, sustainable research, functional requirements, social sustainability, economic sustainability, academic and academic identity and academic diplomacy in the age of globalization. . The results of the quantitative section also showed the difference of sustainability indices in public and non-public universities. Conclusion : Finally, the results showed that universities need to move towards sustainability in order to maintain their stability in the current situation. Sustainable research 3- Functional structural requirements4- Social sustainability 5- Economic sustainability6-Research university7- Academic identity and academy 8- Scientific Diplomacy In the age of globalization. can be achieved through the achievements of Farostokhah (2014),Targhi (2016), Javdani (2015), and Majchrzak (2014) seemed to agree, based on the qualitative findings of the study, indicators of social sustainability in most of the components of social capital production (public awareness of sustainable development through conferences and conferences, active participation in local and national development, community problem solving, solidarity and cohesion). and


Horseradish peroxidase (HRP, EC 22.214.171.124) was used in this study to catalyze oxidative cross-linking of casein in the presence of hydrogen peroxide and cross-linker ferulic acid. Cross-linking of casein was demonstrated by sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and ultraviolet absorbance analysis. Oxidative cross-linked casein mediated by hydrogen peroxide and ferulic acid was prepared at casein concentration of 5% (w/ w), HRP addition of 3 mkat·g-1 proteins, ferulic acid addition of 6 mmol·l-1, 3% (w/w) H2O2 addition of 1 ml, reaction temperature 37°C and reaction time 3 h. Analysis results showed that the emulsifying activity index and emulsifying stability index of cross-linked casein prepared were enhanced compared to that of untreated casein totally. Microstructure of chemical acid-induced gel of cross-linked casein was observed under scanning electron microscopy and appeared to be more compact and uniform than that of casein. Hydrogen peroxide and ferulic acid-mediated oxidative cross-linking of casein catalyzed by horseradish peroxidase might have a beneficial to the emulsifying property or gelation of casein.


Thesis submitted in accordance with the requirements for the degree of
Doctor of Philosophy in the School of Social Science and Policy,
University of New South Wales


A large international study gives reassurance on the safety of xenotransplantation, the use of donor organs from non-human species, to alleviate the shortage of human organs (Science 1999;285:1236-41). Patients exposed to living pig tissue do not seem to have been infected with a pig virus.

Dr Khazal Paradis, director of clinical research at Imutran in Cambridge in the United Kingdom and lead author of the study, told the BMJ: "We hope to proceed to small, well …


According to the up-down construction method in soft soil foundation treatment from design, construction and detection aspects the principle and related technical measures of this construction method are int roduced, which is directed and with short construction time and other advantages .


The invention relates to a component of the domestic appliance (1) for a domestic appliance, wherein said component of household appliance (1) having a microstructured surface (2) at least in sections. The invention also relates to a method for manufacturing a component of the domestic appliance (1) for a domestic appliance, in which a surface (2) component household appliance (1) is at least in sections microstructured.


The present invention is to be a secondary battery, the technical problem to be solved is to prevent such a protection circuit board electrically connected to the bare cell, the developing bias and improve the bonding strength between the protective circuit board and the lead plate. The present invention for this purpose is connected to the charge-discharge terminal, the conductive pads being mounted on the conductive pads, a printed circuit board electrically connected to the protection circuit, the protection circuit portion to be mounted to a printed circuit board, the printed circuit board is mounted to a printed circuit board conductive side to be connected to the pad, discloses a secondary battery protection circuit board made of a lead plate portion formed in at least one receiving solder. Thus, the printed circuit to an improvement in bonding strength between the substrate and the lead plate. Also, the secondary battery using the same are improved the binding force of the printed circuit board and the lead plates are formed in a stable structure. Lead plate, a solder receiving section, the solder flow groove, a circuit board, a conductive pad


The estimation of transport demand in an urban area with a view to planning public transport in Hyderabad, India is described. This city has recorded a population growth rate of 74% between 1981-91 with concomitant increases in the number of private vehicles. Seven transport corridors were selected for study. A bus boarding and alighting study was carried out at 10 major bus stops along a transport corridor in order to produce an origin-destination matrix. Stretches of the corridor with the maximum flow of passengers were determined with a view to timetabling buses to meet demand.


Polymorphism-based luminescence and morphology- and color-dependent optical waveguide properties were observed in two polymorphic CT cocrystals, which result from different mixed stacking structures and intermolecular CT interactions between D and A.


BACKGROUND
Most of bayesian pharmacokinetic studies and the influence of clinical variables have been carried out in adults.

PURPOSE
The aim was to estimate population-based pharmacokinetic of valproic acid (VPA) and to determine the effect of treatment and additional disease on its performance in children with epilepsy.

MATERIAL AND METHODS
For the study steady-state serum concentrations of VPA were determined from 108 epileptic patients (44 females and 64 males) who were receiving the anticonvulsant as main drug of treatment with age range since 1 to 16 years (median 4y, 6m) and weight since 5.2 to 50 kg (median 17.5 kg). All patients had their renal, hepatic and nutritional functions normal. One compartment model using interactive two-stage Bayesian approach was employed in the analysis. RESULTS; Population estimates of CL/F and V/F for VPA were 0.022 +/- 0.013 L/h and 0.217 +/- 0.134 L/kg, respectively. These estimates were significantly affected by weight, age, carbamazepine (CBZ) and gastroesophageal reflux (GER). The final regression models were: CL/F (L/h) = 0.0696 + 0.0031 (Age) + 0.0075 (Weight); and V/F (L) = 0.674 + 0.0308 (Age) + 0.0756 (Weight). Prediction of VPA serum concentration in other validation group revealed an important improvement in the predictive performance of VPA concentrations in comparison with the basic model that did not include any co-variables.

CONCLUSIONS
Based on a population model of children with epilepsy, the pharmacokinetic of VPA could be altered by weight, age and the administration of CBZ and additional GER to epilepsy.


We present the current status of our analysis of nucleon structure observables including isovector charges and twist-2 matrix elements as well as the nucleon mass. Results are computed on a large set of CLS $N_f=2+1$ gauge ensembles with $M_\pi\approx0.130\mathrm{MeV}\ldots 350\mathrm{MeV}$, four values of the lattice spacing $a=0.05\mathrm{fm}\ldots 0.09\mathrm{fm}$ and covering a large range of physical volumes. Compared to the results presented at last year's conference we have added data on a very fine and large box at small light quark mass ($T\times L^3=192 \times 96^3$, $M_\pi=172\mathrm{MeV}$, $a=0.05\mathrm{fm}$). Additional (intermediate) source-sink separations have been computed on the coarser ensembles, further increasing effective statistics and allowing for a more fine-grained control in the treatment of the excited-state contamination. Excited states in the nucleon matrix elements are tamed by a simultaneous, two-state fit ansatz using the summation method.


Modular exponentiation is the most expensive portion of Shor's algorithm. We show that it is possible to reduce the number of quantum modular multiplications necessary by a factor of , at a cost of adding temporary storage space and associated machinery for a table of entries, and performing times as many classical modular multiplications. The storage space may be a quantum-addressable classical memory, or pure quantum memory. With classical computation as much as times as fast as quantum computation, values of from 2 to 30 seem attractive; physically feasible values depend on the implementation of the memory.


Working with psychiatric patients is difficult because of the emotional energy it consumes. "Burnout" is a modern psychopa− thological concept defining physical, emotional and mental ex− haustion caused by long term involvement in emotionally de− manding situations. Contributing factors such as working with difficult client population, long hours with limited resources, ambiguous success, unreciprocated giving


In recent years, Fog Computing is introduced as a powerful extension of cloud computing and services to the edge of the network. Similar to Cloud, Fog provides data, compute, storage, and application services to end users. The fog computing is used to reduce the workload of the cloud computing by bringing basic computing services and analytic services to the edge of network, providing computing resources closer to the end devices, mobility support, improving overall network efficiency and performance and low latency. We explore the different applications of fog computing and various key comparison between cloud computing and fog computing.


In this paper, we will provide an analysis of the potential threats to the reliability and security of IP based voice systems including; voice over IP and IP telephony. For each of the threat categories we will explore the potential methods of attacks and detail various mitigation approaches. These mitigation approaches may help to minimize or eliminate the exposure. Finally, we will provide a set of summary recommendations for dealing with each of the threat categories.


Zirconia Toughened Alumina (ZTA) composites are attractive structural materials, which combine the high hardness and elastics modulus of the alumina matrix with additional toughening effects, due to the zirconia dispersion. In the present study, ZTA composites containing different amounts of zirconia (in the range 0-16 wt %) were prepared by slurry method and sintered at 1450oC and 1550oC for two hour. Microstructure of the composites was observed using scanning electron microscopy and phase content was detected by means of X- ray diffraction. Mechanical properties such as hardness, elastic modulus and flexural strength were measured. Density was increased with the increase of zirconia content for both sintering temperature, while grain size and elastic modulus was decreased with the same change of zirconia content. Hardness and flexural strength were carried out using the Vickers indentation and were discussed as a function of the ZrO2 content and sintering temperature. The toughening effect is attributed mainly to the zirconia t→m phase transformation. About 61% more flexural strength was found for 16 wt % ZTA composites when compared to the pure alumina.


A 61-year-old man, previously treated for a peripheral T-cell lymphoma, presented with symptoms suggestive of disease relapse. He had been unwell for 2 wk with a recurrence of night sweats, fever, lethargy, weight loss and a new skin rash on the torso. On admission he was pancytopenic (hemoglobin 11.2 g ⁄dL, platelets 12 · 10 ⁄L, neutrophils 1.19 · 10 ⁄L) and lactate dehydrogenase (LDH) was markedly elevated to 1593 IU ⁄L. Restaging computed tomographic scan and bone marrow examination confirmed relapsed disease. Large lymphomatous cells with basophilic cytoplasm and pleomorphic nuclei were seen on aspirate smears (Fig. 1 centre) but normal hematopoiesis was preserved. However, florid hemophagocytosis of neutrophils (Fig. 1 left) and erythroid precursors (Fig. 1 right) was present in the same aspirate and this finding in association with recurrent B symptoms and disproportionate cytopenias was suggestive of a secondary hemophagocytic syndrome. Despite the introduction of salvage chemotherapy, the patient deteriorated rapidly and died within few days of admission. Hemophagocytosis by macrophages can occur as a response to a variety of stimuli. The secondary hemophagocytic syndromes are the result of an uncontrolled and severe hyperinflammatory response, generating a constellation of fever, cytopenias and hepatosplenomegaly. The usual triggers are viral, bacterial or fungal infection and malignancy. Of the latter, lymphomas of T-cell and NK cell origin are often implicated. Malignant NK and T-cells appear to produce high levels of pro-inflammatory cytokines such as interleukin-1 and tumour necrosis factor-a leading to excessive activation of histiocytes. This case illustrates a florid example of intramedullary hematopoietic cell consumption by T-cell lymphoma stimulated hyper-reactive bone marrow macrophages.


This Economic Letter looks at how increased managerial focus on employee involvement, quality management, continuous innovation, and incentive-based compensation has boosted labor productivity and draws out some implications for future productivity gains. The research summarized here indicates that the combination of investment in new technology along with workplace innovation has had especially high payoffs to U.S. firms in the 1990s, and, with the continued reorganization of firms, high productivity growth may continue into the future.


Four-stage transistorized ac amplifier provides high input impedance and operates at low intrinsic noise levels. It is suited to carrier or narrow band sine wave applications.


Two large collections of Conus from the Galapagos Islands permitted the analysis of size, sex ratio, and food of 4 of the estimated 13 species of Conus present in the islands. The species investigated were C. diadema, C. lucidus, C. tiaratus, and C. nux. Significantly unequal sex ratios were found in the samples of C. diadema, C. lucidus, and C. tiaratus, but there was no indication of sexual dimorphism in shell sizes. Conus diadema was found to have the most catholic diet of the species, consuming mainly polychaetes of the family Terebellidae, but also sipunculids, mollusks, and eight other polychaete families. Very few food items were recovered from the guts of C. lucidus and most were polychaetes of the families Sabellariidae and Capitellidae. Conus tiaratus and C. nux were both found to feed primarily on polychaetes of the families Nereidae and Eunicidae. In both cases, the dominant species was Nereis jacksoni. Comparison of diets between cognate species in the Galapagos and the Indo-West Pacific indicated the Galapagos species consumed somewhat different prey species. Although there are significantly fewer Conus speCies peihabitafiri the Galapagos than in the Indo-West Pacific, fhere were no significant differences with respect to number of prey species consumed or prey species diversity between the areas. Thus, there was no evidence of decreased dietary specialization in the presence of fewer competing congeners. THE GALAPAGOS ISLANDS and their fauna have elicited considerable interest from biologists since the famous visit of Darwin in 1835. However, most of this interest has been directed at the terrestrial fauna and to the unique assemblage ofmarine vertebrates such as penguins, cormorants, and lizards. Relatively little attention has been paid to the marine invertebrate fauna. Most studies on the marine invertebrate fauna of the islands have been taxonomic or zoogeographic (Bowman 1966) and have generally shown that the marine invertebrate fauna is most closely related to that of the East Pacific and Caribbean (Abbott 1966) rather than the richer Indo-West Pacific. The Galapagos, together with Clipperton and Isla Rivelligegados, represent the most I Manuscript accepted 3 April 1978. 2 Central California State University and Colleges, Moss Landing Marine Laboratories, Moss Landing, California 95039. isolated outposts of the East Pacific Conus species. They are further of interest in that the marine environment is considered to be warm temperate (Abbott 1966) rather than tropical, which is the climate most other Conus assemblages exist under in the East Pacific area. It is thus of some interest to compare the ecology of Conus species assemblages on these islands with similar sets from tropical regions to see if the lack of tropical conditions and the isolated nature of the islands have affected the ecological characteristics of the assemblages. It is the purpose of this paper to begin such an ecological analysis by considering the food and population characteristics of the more common Galapagos species. The specimens upon which this paper is based were collected by J. J. Von Mol of the University of Brussels, Belgium, in 1970 and by G. M. Wellington of the University of California at Santa Barbara in 1973 and 1974. I am greatly indebted to them for placing this material at my disposal.


This case takes the poor performance of the human resources management headquarter of Dalian DG system as a starting point.Through the description of the enterprise interior environment and the whole process of the human resource plan meeting in the headquarter,the paper demonstrates this company's human resources management problems and initial solutions.It also presents the situation on how to carry out the strategic change for the human resources management department when the scale of the organization expands continuously.


Last summer holidays, I was readingthe novel "A visit at Tea-time" in which the leading character called Mr. Williams came back to his old house, where his whole family had spent a happy time fifteen years before. Now, he was an adult and re-


Mechanical Tests and Polymer Transitions * Elastic Moduli * Creep and Stress Relaxation * Dynamical Mechanical Properties * Stress-Strain Behaviour and Strength * Other mechanical Properties * Particulate-Filled Polymers * Fiber- Filled Composites and Other Composites.


The spectroscopic and chemical evidence that the dialkoxythiophosphorylsulfenyl chlorides are formed as intermediates in the chlorination of bis-dialkoxythiophosphoryl disulfides is presented


'[T]here is politics', states Jacques Rancière, 'when the boundary separating the political from the social or the public from the domestic is put into question'. In the immediate wake of the Scottish Independence referendum with the heightened awareness of the space of democracy it engendered, it is a pronouncement that rings all too true. David Greig's work has evolved a long running and complex relationship with politics; as he has said himself: 'in general, I hope to avoid overt political writing. But, I am interested in power and the way that differences in power shape relations between human beings. That inevitably makes my work political.' As a member of the National Collective of Artists and Creatives for an Independent Scotland, and with a series of Yes/No Plays for Twitter begun in December 2013 running through to the referendum in September, 2014 was a year of unprecedented direct engagement for Greig both as an artist and as a citizen. The Yes/No Plays manifestly 'put into question' boundaries in a topical way, but that project is part of what might be described as a broader dissensual tendency in Greig's work that has matured over the last decade to become one of its most distinguishing features. In borrowing some of the spatial orientation of Rancière's thought on politics and aesthetics, this article will map the ways Greig's work harnesses the energies of dissonance and empathy.


We report the temperature-pressure-magnetic field phase diagram made from electrical resistivity measurements for the ferromagnetic (FM) Kondo lattice CeRuPO. The ground state at zero field changes from the FM state to another state, which is suggested to be an antiferromagnetic (AFM) state, above \({\sim}0.7\) GPa, and the magnetically ordered state is completely suppressed at \({\sim}2.8\) GPa. In addition to the collapse of the AFM state under pressure and a magnetic field, a metamagnetic (MM) transition from a paramagnetic state to a polarized paramagnetic state appears. CeRuPO will give us a rich playground for understanding the mechanism of the MM transition under comparable FM and AFM correlations in the Kondo lattice.


Abstract Thermal performance enhancement of microchannel heat sinks for electronics cooling is becoming more and more necessary. To this end, microchannels with noncircular cross-sections conveying immiscible droplets have been employed in this study and geometric manipulations are applied to enhance fluid mixing and consequently achieve a higher rate of heat removal. Three-dimensional numerical simulations are performed using volume of fluid method for channels of 100 µm hydraulic diameter. Constant wall temperature is chosen as the boundary condition for heating section of the channels. Effects of parameters such as adding curvature to the side walls and varying the entering velocity of the base liquid on heat transfer rate are studied. A performance coefficient is used to evaluate the relative impact of increase in both the Nusselt number and pressure drop as a result of adding curvature to the channel walls. Results of the study showed that slug flow in curved channels is capable of improving the thermal performance in comparison with single liquid flow in straight channels and in best case, can improve the performance up to 50%.


Image contrast enhancement is important in medical applications. This is due to the fact that visual examination of medical images is essential in the diagnosis of many diseases. The proposed method use the applicability of the Neural Network approach for image quality classification using a set of key features extracted from the images. If the image is of low quality then it is enhanced with appropriate contrast enhancement technique. The technique can prevent over-enhancement and enhance small details of an image. We focus on chest x-ray and mammogram images. [Monali V. Panchal. A Machine Learning Approach for Contrast Enhancement of Medical Images. Biomedicine and Nursing 2016;2(3): 52-60]. ISSN 2379-8211 (print); ISSN 2379-8203 (online). http://www.nbmedicine.org. 8. doi:10.7537/marsbnj020316.08. Keywords— Contrast; Medical Images; Machine Learning; Enhancement