e19512 Background: With the growing debate about who should oversee cancer survivors' medical care, information on who survivors see post-treatment is needed. This study describes non-Hodgkin's Lymphoma (NHL) survivors' self-reported patterns of post-treatment care.

METHODS
Using a population-based sample from the Los Angeles County Surveillance Epidemiology and End Results (SEER) registry, we surveyed survivors of aggressive NHL 2-5 years after diagnosis. Our analytic sample included NHL survivors whose cancer was in remission at study enrollment (N=363).

RESULTS
Nearly all survivors (N=334, 92%) received cancer-related follow-up care in the past year; most (N=297, 89%) were followed primarily by an oncologist and only 23 (7%) were followed primarily by a primary care physician (PCP). Of those followed by an oncologist, 92% reported more than one visit; 15% reported >5 visits. 263/297 (89%) survivors followed by an oncologist reported on additional care. Four distinct patterns of care emerged: 13% saw only oncologists; 19% saw oncologists plus other specialists; 20% saw oncologists plus PCPs; and 48% received care from oncologists, other specialists, and PCPs. Survivors with a history of recurrence, radiation treatment, or bone-marrow/stem cell transplant were more likely to see only oncologists (p < .01). Survivors who reported greater limitations due to comorbidities (p=0.001) or greater symptom burden (p<0.05) were more likely to also see other providers (PCP, other specialists, or both). Time since diagnosis, grade of NHL, health information needs, perceived health competence, perceived risk of recurrence, and sociodemographics were not related to patterns of care.

CONCLUSIONS
Most NHL survivors receive regular follow-up care from an oncologist 2-5 years after diagnosis. Survivors with greater disease risk (recurrence, radiation therapy, transplant history) are cared for in oncology only, while those with greater comorbidity and symptom burden also received care from other specialists and PCPs. Patterns of care appear to be matched to patient needs. The high proportion of NHL survivors receiving care from multiple providers suggests that special attention may need to be paid to coordinating care across specialties.


Cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4; CD152) is a member of the immunoglobulin gene superfamily with strong homology to the receptor CD28 with which it shares the ligands CD80 and CD86. Unlike CD28, a potent costimulator of T‐cell responses, CTLA‐4 is transiently expressed on the cell surface of activated T cells and appears to operate predominantly as a negative regulator of T‐cell proliferation. Signal transduction mechanisms utilized by CTLA‐4 remain unclear although several mechanisms have been implicated. In this study, we show that the cytoplasmic domain of CTLA‐4, but not of CD28, binds to STAT5 in yeast two‐hybrid assay and in coimmunoprecipitation assays. Mutations of Tyr165 and Tyr182 in CTLA‐4 did not abrogate the interaction of STAT5 with CTLA‐4. Finally, the overexpression of CTLA‐4 in Jurkat T cells inhibits STAT‐mediated activation of STAT5 responsive elements. These results suggest that CTLA‐4 and STAT5 interact in T cells and that this interaction is important for CTLA‐4 signalling.


Background and purpose: Ghrelin, a natural ligand of the growth hormone secretagogue receptor plays a major role in regulation of appetite, body fat mass, and energy balance in the body. The aim of this study was to evaluate the effects of maternal diabetes on circulatory ghrelin levels in rat newborns. Materials and methods: In this experimental study, female Wistar rats were allocated into diabetic (n=20) and control (n=10) groups and mated with males. After parturition, 16 offspring (8 males) were collected at both postnatal days (P), P7 and P14. The body weight, blood glucose and plasma ghrelin levels were measured. Data were analyzed applying two-way ANOVA using sex and group as the factors in SPSS V22. Results: At both P7 and P14, the body weight of newborns of diabetic mothers (18.49± 0.42g, 22.27± 0.43g respectively) were significantly lower (P<0.0001 each) than those of the control group (22.34± 0.402g, 30.32± 1.45g) while there were no significant differences in blood glucose levels between the two groups. At P7, plasma ghrelin levels showed no significant difference between experimental and control groups, but at P14, experimental group had markedly higher ghrelin levels than that of the control group (29.25± 3.59 pg/ml vs. 14.81± 2.75 pg/ml; P<0.0001). Moreover, at P14, male offspring had significantly higher level of ghrelin than female (29.87± 2.58 pg/ml vs. 22.62±1.68 pg/ml; P<0.0001). Conclusion: Current results clearly demonstrate that diabetes during pregnancy can influence plasma ghrelin levels with male and female offspring responding differently.


The goal of this 3-year project was to facilitate a more productive dynamic matching between resource providers and resource consumers in Grid environments by explicitly specifying policies. There were broadly two problems being addressed by this project. First, there was a lack of an Open Grid Services Architecture (OGSA)-compliant mechanism for expressing, storing and retrieving user policies and Virtual Organization (VO) policies. Second, there was a lack of tools to resolve and enforce policies in the Open Services Grid Architecture. To address these problems, our overall approach in this project was to make all policies explicit (e.g., virtual organization policies, resource provider policies, resource consumer policies), thereby facilitating policy matching and policy negotiation. Policies defined on a per-user basis were created, held, and updated in MyPolMan, thereby providing a Grid user to centralize (where appropriate) and manage his/her policies. Organizationally, the corresponding service was VOPolMan, in which the policies of the Virtual Organization are expressed, managed, and dynamically consulted. Overall, we successfully defined, prototyped, and evaluated policy-based resource management and access control for OGSA-based Grids. This DOE project partially supported 17 peer-reviewed publications on a number of different topics: General security for Grids, credential management, Web services/OGSA/OGSI, policy-based grid authorizationmore » (for remote execution and for access to information), policy-directed Grid data movement/placement, policies for large-scale virtual organizations, and large-scale policy-aware grid architectures. In addition to supporting the PI, this project partially supported the training of 5 PhD students.« less


Instead of forwarding to a specific device or to all devices in a group, anycast addresses, let network devices forward a packet to (or steer it through) one or more topologically nearest devices in a specific group of network devices. The use of anycast addresses has been extended to the Segment Routing (SR) network, wherein a group of SR-capable devices can represent a anycast address, by having the same Segment Routing Global Block (SRGB) provisioned on all the devices and each one of them advertising the same anycast prefix segment (or Anycast SID). This document describes a proposal for implementing anycast prefix segments in a MPLS-based SR network, without the need to have the same SRGB block (label ranges) provisioned across all the member devices in the group. Each node can be provisioned with a separate SRGB from the label range supported by the specfic hardware platform. Requirements Language The key words "MUST", "MUST NOT", "REQUIRED", "SHALL", "SHALL NOT", "SHOULD", "SHOULD NOT", "RECOMMENDED", "MAY", and "OPTIONAL" in this document are to be interpreted as described in RFC 2119 [RFC2119]. Status of This Memo This Internet-Draft is submitted in full conformance with the provisions of BCP 78 and BCP 79. Internet-Drafts are working documents of the Internet Engineering Task Force (IETF). Note that other groups may also distribute Sarkar, et al. Expires October 15, 2016 [Page 1] Internet-Draft Anycast Segments in MPLS-based SR April 2016 working documents as Internet-Drafts. The list of current InternetDrafts is at http://datatracker.ietf.org/drafts/current/. Internet-Drafts are draft documents valid for a maximum of six months and may be updated, replaced, or obsoleted by other documents at any time. It is inappropriate to use Internet-Drafts as reference material or to cite them other than as "work in progress." This Internet-Draft will expire on October 15, 2016.


The active control of the radial current density profile is one of the major issues of thermonuclear fusion energy research based on magnetic confinement. The lower hybrid current drive could in principle be used as an efficient tool. However, previous understanding considered the electron temperature envisaged in a reactor at the plasma periphery too large to allow penetration of the coupled radio frequency (RF) power due to strong Landau damping. In this work, we present new numerical results based on quasilinear theory, showing that the injection of power spectra with different n // widths of the main lobe produce an RF-driven current density profile spanning most of the outer radial half of the plasma ( n // is the refractive index in a parallel direction to the confinement magnetic field). Plasma kinetic profiles envisaged for the DEMO reactor are used as references. We demonstrate the robustness of the modeling results concerning the key role of the spectral width in determining the lower hybrid-driven current density profile. Scans of plasma parameters are extensively carried out with the aim of excluding the possibility that any artefact of the utilised numerical modeling would produce any novelty. We neglect here the parasitic effect of spectral broadening produced by linear scattering due to plasma density fluctuations, which mainly occurs for low magnetic field devices. This effect will be analyzed in other work that completes the report on the present breakthrough.


The paper provides a how to do it management system for small firms interested in joint venturing. The writer relates various experiences and points out practical problems to eliminate guesswork, avoid pitfalls, and reduce costly trial and error methods.


Objective
To explore the effects of clinical psychic care on the physical and mental state of the elderly patients with advanced gastric cancer.

Methods
From June 2016 to June 2017, a total of 90 cases of elderly inpatients with advanced gastric cancer in the Affiliated Tumor Hospital of Zhengzhou University were selected by convenience sampling method. According to the random number table, all the research subjects were divided into the observation group and the control group, with 45 cases in each. The control group was given routine nursing, while the observation group was given clinical psychic care on the basis of the control group. The negative emotions (anxiety, depression, fear) , physical state and quality of life of the patients were compared with Hamilton Anxiety Scale (HAMA) , Hamilton Depression Scale (HAMD) , Visual Analogue Scale for Fear (FAVS) , Karnofsky Performance Status (KPS) , Performance Status (PS) and Cancer 30-item Quality of Life (QLQ-C30) between the two groups.

Results
There was no statistical significance in the difference of negative emotion, physical state and quality of life between the two groups before intervention (P>0.05) . After the intervention, the scores of HAMA, HAMD and FAVS of the two groups were lower than those before the intervention. In addition, the scores of the observation group was lower than those of the control group, with statistical difference (P<0.05) . The KPS score of the two groups was higher than that before the intervention, and the PS score was lower than that before the intervention. The KPS score of the observation group was higher than that of the control group, while PS score was lower in the control group. All the differences were statistically significant (P<0.05) . After intervention, the scores of general health status, physical function, emotional function and social function in the observation group were higher than those in the control group, while the scores of pain, nausea and vomiting, fatigue, loss of appetite and insomnia in the observation group were lower than those in the control group (P<0.05) .

Conclusions
The use of clinical psychic care in elderly patients with advanced gastric cancer can obviously improve the mental state, physical state and quality of life of the patients, which is worthy of clinical promotion.

Key words:
Aged; Stomach neoplasms; Psychic care; Physical and mental state


The objectives of the research discussed in this report were (1) to determine typical service lives for each type of pavement marking materials now widely used in this country and (2) to develop guidelines for selecting the most appropriate materials on the basis of estimated life-cycle costs. To achieve these objectives, it was necessary to develop criteria for estimating the service life of the marking materials now in use and a method for estimating the life-cycle cost of the materials. The criteria for estimating the service lives of the materials were developed from the results of a panel study in which 16 drivers provided user ratings of lines in service in Pennsylvania. This information together with the results of the experimental test line programs in Pennsylvania, Florida, and Arizona provided the basis for the findings in this report. Volume I contains the technical report and Volume II the appendices.


Detecting concurrency relations between events is a fundamental primitive in process mining. Existing approaches to this problem identify concurrency relations between pairs of event types under a global interpretation. If two event types are found to be concurrent, every occurrence of one event type is deemed to be concurrent to one occurrence of the other. In practice, this assumption not always holds. This paper proposes a finer-grained approach, whereby two event types may be in a concurrency relation relative to one state of the process, but not relative to other states, i.e. the concurrency relation holds locally. Experimental results both with artificial and real-life logs show that the proposed local concurrency detection approach improves the accuracy of existing concurrency detection techniques.


An application concept of the MIMO technique, which is very well known from a radio transmission to increase a total information capacity of multimode fibers was discussed. The focus has been mainly on an incoherent version of this technique. Additionally an experimental setup based on the such approach has been described in a second part of the paper. The system cooperated with an OM2 50 μm GI silica fiber with 4.4 km of a length. Two digital streams with a 200 Mbit/s rate each had been transmitted simultaneously in the same band of the frequency beyond a baseband of the multimode fiber.


Multi-modal data is becoming more common than before because of big data issues. Finding the semantically equal or similar objects from different data sources(called entity resolution) is one of the heart problem of multi-modal task. Current models for solving this problem usually needs much paired data to find the latent correlation between multi-modal data, which is of high cost. A new kind latent correlation is proposed in this article. With the correlation, multi-modal objects can be uniformly represented in a commonly shard space. A classifying based model is designed for multi-modal entity resolution task. With the proposed method, the demand of training data can be decreased much.


Dr. Giuseppina Imperatore is Team Lead, Epidemiology and Statistics Branch, Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, at the Centers for Disease Control and Prevention, Atlanta, GA. Dr. Elizabeth J. Mayer-Davis is Professor and Chair, Department of Nutrition, Gillings School of Global Public Health and School of Medicine, at the University of North Carolina, Chapel Hill, NC. Dr. Trevor J. Orchard is Professor of Epidemiology, Medicine & Pediatrics, Department of Epidemiology, Graduate School of Public Health, at the University of Pittsburgh, Pittsburgh, PA. Dr. Victor W. Zhong is with the Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.


Because connected speech presented through a multichannel tactile speech aid results in a complex and rapidly changing signal, it has been assumed that subjects having no prior tactile aid experience would require considerable amounts of "analytic" tactile training with phoneme and word‐level single‐item identification tasks, before they could usefully interpret connected speech. While it is the case that subjects who receive substantial amounts of analytic training with tactile aids perform better than subjects with no training, it may be the amount of prior experience, rather than the specific training tasks employed, that determines asymptotic performance levels. In the present study, groups of subjects were trained with a multichannel tactile aid in either an "analytic" condition (a graduated series of single‐item tasks) or a "nonanalytic" condition (connected speech tracking only). Each group received the same number of hours of tactile aid experience. During the final 20 h of the study, all subjects...


This study was designed to investigate the nature of the course of functional outcome across the four patient groups with diabetic neuropathy at consequent stages of foot complications namely: diabetic neuropathy without history of plantar ulceration (DMPN), active plantar ulceration (DFU), healed unilateral partial foot amputations (PFA) and healed unilateral trans-tibial amputations (TTA). The secondary objective was to compare the functional outcome between patients with DFU and PFA and patients with PFA and TTA. Methods: In this cross-sectional case control study, 4 matched groups of patients with DMPN were studied: DMPN (n=23); DFU (n=23); PFA (n=16) and TTA (n=22). Appropriate outcome measures were used to evaluate function in 3 domains, namely Mobility and its impact on weight-bearing (sit-to-stand, standing balance, gait and plantar pressures during walking), Level of Activity (capacity and performance of walking) and H-RQOL. One-way ANOVA was used to compare 4 groups and linear polynomial contrast detected the trend across groups. In cases of significant difference between the 4 groups, an Independent sample t-test was used for specific group comparison. Results: There was a significant difference in functional outcome between the four groups demonstrating an overall decline in the level of function with the progression of impairment (standing balance: p=0.002, gait velocity: p<0.001, daily strides: p<0.001, SF-36 Physical function: p<0.001). The risk of plantar injury to the entire affected foot during walking increased from DMPN to DFU to PFA (p=0.013). There was no significant difference between the overall function of DFU and PFA. The PFA and TTA groups also varied significantly only in the domain of activity performance wherein the TTA group demonstrated a low daily walking performance compared to the PFA group (p=0.006). Conclusion: The overall decline demonstrated in this study in the three domains of function with progression of physical impairment from the DMPN to TTA group, calls for an urgent need to define a tailormade rehabilitation programme to maximise function of these patient groups. The increasing risk of plantar injury from DMPN to DFU to PFA during walking warrants a greater and precise focus on footcare of the affected as well as the contra-lateral foot.


Despite the tremendous advances that have been made recently in bringing better and safer anaesthesia to millions of people throughout the world, there is still one aspect of our speciality which receives only scant attention. Obstetrical analgesia and anaesthesia have perhaps aptly been called the Cinderella of anaesthesia. Whether it be due to economics, lack of manpower, or just lack of interest, the provision of an adequate service for pain relief in labour (organised by an anaesthetic department) is still very backward, even in some of the wealthiest countries. This symposium is designed primarily to stimulate an interest in the provision of a clinical service to alleviate the pain of childbirth. There are many ways of approaching this problem, but time allows for only a brief consideration of the most recently developed techniques. The particular method chosen by any anaesthetist must be based on experience and an intimate knowledge of


The utility model discloses a male penis body-building massage instrument, which is applied to male penis health care. A touch display screen is divided into three modules; an electrical stimulation control touch screen display interface, a sperm taking control touch screen display interface and a gas-liquid combined massage control touch screen display interface can be respectively used for electrical nerve stimulation, simulated vaginal environment sperm taking and gas-liquid combined massage health care of penis through a stimulating electrode, a sperm taking cylinder and a negative pressure cylinder; the stimulating electrode is connected and communicated with the massage instrument through an electrical stimulation output port I, an electrical stimulation output port II and an electrical stimulation output port III to act; the sperm taking cylinder is embedded into the message instrument; and the negative pressure cylinder is connected and communicated with the massage instrument through connection of a negative pressure output port and a negative pressure port of the negative pressure cylinder and connection of a liquid injection output port and a liquid injection port of the negative pressure cylinder to act. The massage instrument has the beneficial effects that electrical nerve stimulation, simulated vaginal environment sperm taking and gas-liquid combined massage health care of the penis can be realized, and the massage instrument supports video play; and through sports health care, the probability of impotence can be effectively reduced.


A new methyl-functionalized metal-organic framework, {Cu3(CMPEIP)2*2H2O}n (m-NB13, H3CMPEIP = 5-((4-carboxy-2-methylphenyl)ethynyl)isophthalic acid) was solvothermally synthesized and structurally characterized. {Cu3(CMPEIP)2*2H2O}n exhibits a high BET surface area of 3215.4 m2 g1, large H2 uptake (1.92 wt% at 1 bar and 77 K), and excellent CO2 storage capacity(9.24 wt% at 1 bar and 298 K).


Nanxi River is one of the largest tributaries in the lower reaches of Oujiang River. There are many traditional villages along the river. When there are more rainy seasons or typhoon storms, floods will occur in the basin. There is Shizhu hydrological station on the main stream of Dananxi in the lower reaches of the basin. Shizhu station is the flood control station in the middle and lower reaches of Nanxi River, which plays an important reference role in flood prevention of Nanxi River. Due to the influence of many factors, rainfall data contains system noise and measurement noise. The analysis and calculation of the model parameters from the rainfall series with noise can not truly reflect the nature of the rainfall system. The reliability of data and the accuracy of data analysis results can be improved by denoising rainfall series. In this paper, the wavelet denoising method is used to denoise the annual rainfall series of Shizhu station, and its useful rainfall data is obtained. The amount of rainfall has a direct impact on the socio-economic development along the line, the health of the ecological environment and the people's living and working in peace and contentment on both sides of the Nanxi River. The research results can provide basic data for flood control and water resources utilization of Nanxi River, and enable relevant departments to take measures in advance to ensure the safety of people's living environment and sustainable development of ecological environment, and provide technical support for Rural Revitalization in Nanxi River.


As a representative figure of the local art,Luo Zhongli has been persisting in creation about the local art since he initiated a fashion of the local art in the 1980's.Luo Zhongli successively aspires after a profound expression and originality in art:on the themes of his works takes on a change from the representation of local customs to the excavation of local culture and in his expressive mode embodies some transformations from an objective representation to a subjective expression and from the imitation of the west local art to the incessant creation in expressive form,which reflects a definite aspiration of the localization in his local art.


The effect of strengthening the fire fighting forces with science and technology was discussed based on the analysis of main idea or connotation.The suggestions of enhance the construction of talent team,science popularization and application,financial input were put forward according to the problems in strengthening the fire fighting forces with science and technology.


This paper discusses the adoption of using LED-based lamps as compared with the incandescent lamps. LED lamps contain an assortment of highly engineered components. The generic example shown here includes an array of white-light LEDs and the electronic circuitry to drive them, all packaged in a compact screw-in unit.


Objective:To explore the use of a simulation rescue training nursing staff capacity and improve the practical effect.Methods:To see clinical common dying cases of rescue,and out the rescue procedures,study and training.the demonstration.Results:Situation after implementation of training,the nurse of first aid and comprehensive quality been improved obviously(P0.05),the doctor′s care the patient′s satisfaction rate and patients to save a tremendous success rate would increase(P0.05).Conclusion:Use scenario walkthrough could improve the quality of the nursing staff and thus enhance dying the patient′s saving rate.


Extraction, isolation and purification of an antimicrobial peptide was carried out from flowers of Pisum sativum and its antimicrobial activity was assessed against Escherichia coli and Staphylococcus aureus. The results showed that Pisum sativum flowers purified extract has antibacterial activity against Escherichia coli and Staphylococcus aureus. Hence providing protection to the flowers against pathogen invasion. This also showed that an antibacterial compound has been isolated and detected.


The software product line (PL) approach promotes the generation of specific products from a set of core assets for a given domain. This approach is applicable to domains in which products have well-defined commonalities and variation points. Variability management is concerned with the management of the differences between products throughout the PL lifecycle. This paper presents a UML-based process for variability management that allows identification, representation and delimitation of variabilities; and, identification of mechanisms for variability implementation. The evaluation of the process was carried out as a case study within the context of an existing PL for the Workflow Management System (WfMS) domain. The results have shown that the proposed process includes well-defined control mechanisms that increase the possibility of identifying and tracing variabilities.


New remote sensing technologies are now available to lower the cost of doing strategic surveys. A new sampling approach for the Forest Inventory and Analysis program (FIA) of the U.S.D.A. Forest Service is discussed involving a bi-sampling unit (BSU) that is composed of a field sample unit (FSU) centered within a large scale (1:1,000 to 1:3,000) photo sample unit (PSU) of the same size and shape. Within the PSU, a circular plot size is used for timber inventory and a strip plot for riparian buffer assessment and down woody material. On PSUs in previous studies in Alaska and Washington we counted or measured individual trees, tree height, crown area by digitizing the perimeter, plot crown closure, tree crown closure, tree branch density, plot area, and tree type (species and decay class). FSUs provide ground truth for PSUs as well as permanent and forest health plot information. Data for core FIA variables such as species, diameter, crown class, rotten/missing cull, and decay class may also be furnished by FSUs. National gross board foot volume per hectare estimates will be made from PSUs. Then permanent FSUs will provide growth, mortality, and defect factor information that are combined with the PSU estimates. Integration of PSUs with simultaneously collected Lidar data is used to improve tree height measurement accuracy in dense forest stands by providing local digital elevation models. Annual national estimates of stocking, mortality, and growth by tree species or forest type are obtained on a random sample chosen from a grid. Strata will be superimposed over this grid. The FSUs collected in the past will be incorporated in the new design which has the potential to result in a 50 percent reduction in cost relative to current FIA.


We perform a beam-beam parameter study for a TeV-scale PWFA (particle-driven plasma wakefield acceleration) $\mathrm{e}^+$$\mathrm{e}^-$ linear collider using GUINEA-PIG simulations. The study shows that the total luminosity follows the $1/\sqrt{\sigma_z}$-scaling predicted by beamstrahlung theory, where $\sigma_z$ is the rms beam length, which is advantageous for PWFA, as short beam lengths are preferred. We also derive a parameter set for a 3 TeV PWFA linear collider with main beam parameters optimised for luminosity and luminosity spread introduced by beamstrahlung.
Lastly, the study also compare the performance for scenarios with reduced positron beam charge at 3 TeV and 14 TeV with CLIC parameters.


We have developed an interface for analytical scale high-performance liquid chromatography (HPLC)/NMR and flow injection analysis (FIA)/NMR. FIA/NMR is less demanding than LC/NMR, so the flow cell was designed to minimize LC/NMR problems and allow the use of a commercial NMR probe for detection. The cell reported here is simple to construct, has reasonable sensitivity, and has good resolution.


With the great progress in supercomputers and the numerical methods, the application of computational fluid dynamics are advancing rapidly in the field of ship hydrodynamics. And the dynamic overset grid method makes it possible for computing complex ship motions, e.g. ship self-propulsion with moving propellers and rudders. In the present work, CFD-based method coupling with dynamic overset grid technique is applied to investigate the hydrodynamic performance of the fully appended ONR Tumblehome ship model during selfpropulsion condition. Open water performance of propeller and towing condition of bare hull are computed before the self-propulsion simulation. The ship model is fitted with twin rotating propellers and twin static rudders, achieving self-propulsion model point at Fr=0.2 and Fr=0.3, respectively. All the computations are carried out by our in-house CFD solver naoe-FOAM-SJTU, which is developed on the open source platform OpenFOAM and mainly composed of a dynamic overset grid module and a full 6DOF motion module with a hierarchy of bodies. The CFD code naoe-FOAM-SJTU solves the Navier-Stokes equations for unsteady turbulent flows with VOF method capturing free surface around the complex geometry models. During the self-propulsion simulation, a feedback controller is used to update the rate of revolutions of the propeller to achieve the target speed. Detailed information of the flow field during the self-propulsion condition is presented and analyzed. In addition, predicted results, i.e. ship motions and force coefficients, are also presented and compared with the available experimental data. Good agreements are achieved which indicates that the present approach is applicable for the self-propulsion simulation.


Serum amino-terminal pro-brain natriuretic peptide (NT-proBNP) is considered as a prognostic marker in patients with severe sepsis or septic shock, but no data are available on NT-proBNP kinetics in hematological patients with neutropenic fever. Altogether 70 hematological patients with neutropenic fever were included in this prospective study. NT-proBNP and C-reactive protein (CRP) were determined at the beginning of the neutropenic fever (d0) and then daily up to 3–4 days. The median NT-proBNP (interquartile range) increased from 127 (57–393) ng/L on d0 to 542 (194–1385) ng/L on d4. The increment of CRP was from 35 (17–61) mg/L on d0 to 109 (56–109) mg/L on d2. Neither serial NT-proBNP nor CRP predicted development of severe sepsis, but NT-proBNP was significantly higher in patients with previous cardiovascular disease than in those without. NT-proBNP seemed to reflect cardiac distress, but it did not help to predict the development of severe sepsis in this patient group.


Five patients underwent cerebral revascularization operations during which Biemer clips were used to occlude temporarily a branch of the middle cerebral artery. Postoperative angiograms revealed stenoses at the sites where the clips were applied. Excessive clip closing forces may have caused significant endothelial injury, which then produced the stenoses. Clips that exert a minimal occlusive force would avoid this response and are recommended for temporary occlusion of cortical arteries.


Spectrum analysis of microwave signals can be performed using Bragg diffraction of light by magnetostatic waves (MSW's). MSW wave propagation must occur in a thin-film magnetic, ferrite medium, such as YIG. Since it is possible to propagate guided optical waves in the same film, rf spectrum analyzers analogous to those using guided optical wave interaction with surface acoustic waves can be constructed. Intrinsic advantages of the optical-MSW device include high center frequencies of operation, up to 20 GHz and beyond, and tunability of the center frequency. The theory of optical-MSW interactions and laboratory demonstrations of such interactions are summarized. Design considerations for a spectrum analyzer device are discussed, including materials, rf-to-MSW transduction, light sources, thin-film light coupling, and photodetectors. I. Introduction Magnetostatic waves (MSW's) are slow-velocity electromagnetic waves (velocities in the range 10^ - 10^ cm/s) propagating in a ferrite medium (a dielectric, magnetic, material such as yittrium iron garnet,Y3Fe50^2 or YIG) which is situated in an external magnetic field. Associated optical refractive-index changes occur due to the Faraday effect, and these changes act as a phase grating capable of diffracting light. Such diffraction was first observed with MSW's and magnetoelastic waves in bulk samples (bars, slabs, and rods) of ferrite materials.^"^ However, no useful devices followed from those experiments, because those bulk geometries have internal magnetic nonuniformities due to shape-factor demagnetization^ which result in differing MSW dispersion at various locations in the sample. A thin-film geometry, however, has a uniform internal field.9'10 Bragg diffraction of guided optical waves has recently been produced in thin-film geometries where the optical beam is collinear toll or transverse to 12 the MSW propagation directions. Both geometries are useful for a number of applications; rf spectrum analysis using the transverse, deflector geometry will be the primary application of interest here, although correlation/convolution, optical filtering, optical switching, and optical isolation are other potential applications. The optical-MSW interaction is in many ways exactly analogous to the opto-acoustic interaction used for rf spectrum analysis. However, use of MSW's provides several signifi cant potential advantages in addition to those already recognized for the acousto-optic spectrum analyzer.13 MSWTs can be generated at frequencies up to 20 GHz and beyond,14 whereas acoustic waves cannot be efficiently excited at frequencies beyond a few GHz due to material acoustic attenuation.15/16 The high center frequencies obtainable with MSW's can simplify an optical rf spectrum analyzer architecture. In an acousto-optic spectrum analyzer, high-frequency signals must be downconverted to a frequency that is acceptable by the acoustic cell, as shown in Fig. 1; this requires the use of filters, local oscillators, mixers and additional amplifier gain. An optical-MSW device (such as illustrated in Fig. 2) would have the advantage of directly transducting the high-frequency signals. A second advantage is that the frequency band of the MSW is determined by the strength of an applied DC magnetic field; hence, utilization of an MSW at a different frequency band simply requires changing bias-field value. In the following section, the theory of the interaction between guided optical waves and MSW's is reviewed. Next, we describe recent laboratory demonstrations and compare the results with the theory. These provide the details of performance parameters and limits of spectrum analyzer devices based on this interaction. Then an analysis is given of various technological approaches for obtaining a high-frequency, large-time-bandwidth, high-dynamic-range spectrum analyzer. II. THEORY An MSW is described by Maxwell's equations, which together with the thin-film boundary conditions of the sample geometry result in solutions for the rf fields associated with the signal and for the dispersion relation, i.e., the MSW wave vector magnitude km slj^l as a function of the microwave frequency, ft. Referring to Fig. 2, four types of solutions are_ found9/17/18 according to specific relative orientations of the biasing external field (H0), the MSW wave vector km, and the normal to the thin-film surface (n). There are two dielectric-waveguide-like waves called forward volume waves (FVW) and backward volume waves (BVW, with negative group velocity), and two types of magnetostatic surface waves (MSSW).


Nested/microcystic (NV/MV) urothelial carcinoma (UC) variants are associated with mild cytologic atypia and commonly present at high‐stage disease. The histopathogenesis is investigated using urothelial basal cell markers. Archival 14 NV/MV and three inverted papilloma (IP) were immunostained for CD44, cytokeratin 5 (CK5), CK34bE12 and p63. Twenty consecutive cases of invasive high‐grade UC including 14 superficial and 6 muscle‐invasive UC cases were used as control. Immunostaining was scored as high for staining of full or more than 50% thickness of the epithelial nest or epithelium and low for lesser immunoreactivity and negative reactivity. All 14 NV/MV, 3 IP and 6 control cases showed a high score of immunoreactivity for CK5, CD44, CK34bE12 and focally for p63. The remaining control cases showed a high score of immunoreactivity for CK34bE12, while negative or low for CK5, CD44 and p63. In conclusion, immunoreactivity CK5 and CD44 commonly immunostained NV/MV and some invasive high grade UC. Other basal cell markers (CK34bE12 and p63) appear to be non specific or non sensitive. NV and MV and some UC likely represent a subset of UC displaying immunohistochemical features of urothelial basal cells. They had tendency of endophytic growth and early invasion despite the innocuous cytologic appearance.


Objective Specific risk alleles for childhood-onset SLE (cSLE) versus adult-onset SLE (aSLE) patients have not been identified. The aims of this study were to determine if: 1) There is an association between non-HLA-related genetic risk score (GRS) and age of SLE diagnosis; and if 2) There is an association between HLA-related genetic risk score and age of SLE diagnosis.


The focus of feminist debates on social reproduction has been both conceptual (what delimits domestic/work? In what ways is it gendered? What does this gendered understanding tell us about the way in which capitalism/society reproduces itself? What are the political and discursive struggles around and against these delimitations of the domestic/work…) as well as methodological (how/can domestic work be measured? What has been less focused on is the obverse side – what happens when the domestic/work is not taken into account? Not simply in terms of policy outcomes or discursive political norms about who 'works' and who doesn't but in terms of the bodies, spaces, communities and relationships that form the network of our everyday lives. It is this aspect that I address through examining two intersecting conceptual axes – depletion and/in everyday political economy.


In previous paper score level fusion performance is tested with various matching score proportions with Iris and Palm print images. Here feature level fusion is done using fractional energy of transform with Iris and Palm print biometric traits. The benefit of energy distribution of transforms in higher coefficients is taken here to reduce the feature vector size of image. Iris and Palm print are together taken here for identification with fractional energy of Slant, Walsh, Haar, Hartley and Kekre, Sine, Cosine transformed Palm and Iris images. The test beds of 60 pairs of Iris and Palm print samples of 10 persons (6 per person of iris as well as Palm print and fused Iris: Palm print) are used as test bed for experimentation. Experimental result in feature level fusion of Iris: Palm print using Hartley transform with (1:3) threshold gives highest GAR value.


The main objective of the study is to develop a recommendation system for movies by implementing a combination of three different algorithms: Collaborative Filtering, Content Based Filtering and Pearson Correlation Coefficient. The proposed system is a web-based application that can provide recommended movie titles based on search queries, item attributes, user historical data and user preferences. The study shows that the combination of the three algorithms is effective at n and more efficient. The combination of the implemented algorithms is not limited to providing movie recommendations alone, it can also be modified and applied on different platforms such as an e-commerce, social media, news article websites and other fields.


Objective
To discuss the application and effect of formative assessment in orthopedic undergraduate clinical teaching for undergraduates.

Methods
To choose 80 clinical medicine undergraduates in grade 2012 of Wuhan University as the research objectwhich were randomly divided into experimental group and control groupwith 40 undergraduates in each group. In orthopedic undergraduate teaching, experimental group was used by the formative assessment, and control group was used by traditional summative evaluation. After teaching finished the result and effect of teaching evaluation were evaluated by the examination and questionnaire survey.

Results
The examination scores in the experimental group were significantly higher than those of the control group, which had significant statistical difference (P<0.05). The questionnaire results showed that the scores in the experimental group were significantly higher than those of the control group and the satisfaction of students in the experimental group was also significantly better than that in the control group, there were significant statistical difference (all P<0.05).

Conclusions
Formative assessment used in orthopedic undergraduate teaching could improve students' scores and improve the quality of teaching.

Key words:
Formative assessment; Orthopedics; Undergraduates; Clinical Teaching


otheroppressed groups can be refused. A telling example is the argument by some women suffragists in the late nineteenth century that an extension of voting rights to (white) women would counterbalance the electoral influence of African Americans. I found other examples less persuasive. Bob argues that western governments' support for LGBT rights in Africa and women's rights in post-9/11 Afghanistan used ''rights as dynamite,'' a practice he defines as the ''attempt to undermine or destroy a targeted culture or community'' (p. 120). But awareness that one's efforts to promote LGBTrights or women's rights will provoke cultural resistance does not mean that one promotes such rights in order to overturn another (or one's own) culture. The real issue raised in Bob's examples is not the use of rights to overturn culture but the use of coercion to promote rights—in Africa, threatened withdrawals of foreign aid, and in Afghanistan, the use of military force to prevent a Taliban resurgence. Bob argues that advocates use ''rights as spears'' when they use courtroom challenges to overturn laws and policies deemed to violate rights. As one example, he cites the NAACP legal campaign leading to the Supreme Court decision in Brown v. Board of Education that school segregation violated the Constitution. I think this argument is misleading. When rights advocates challenge laws on constitutional or human rights grounds, they do not use rights as spears, but instead use legal arguments to vindicate rights. Using Bob's logic, one could as easily say that a patient uses health as a spear when seeking medical treatment. Bob correctly notes the attraction of rights terminology for a wide variety of political actors, and he sheds valuable light on cynical and opportunistic uses of rights claims. He overstates the case (in my view) when he obscures the distinctive significance of human rights and sometimes makes mistaken attributions of instrumental reasoning. It makes a difference whether we act on behalf of human rights or unrelated demands describable, as almost any demand can be, in the formal language of ''rights,'' and it makes a difference whether those claiming to act on behalf of human rights do so genuinely and sincerely. Human rights help us with the task of sifting just from unjust political demands. We misunderstand human rights when we cast them as strategy.


A 30-year-old man had a 6-year history of episodic flushing of the face, upper chest and upper arms. This occurred especially after alcohol ingestion, but was also triggered by stress or heat; onset was within minutes and duration of each episode generally less than an hour. Until 18 months previously, he had been employed at a factory manufacturing printed circuit boards, where DMF was used as a solvent in the resin production area. The patient felt that this agent was the cause of his symptoms as he had been asymptomatic in the same occupation until DMF was introduced, about 10% of his workmates were affected, workers at European branches of the same factory had apparently experienced similar symptoms, and the symptoms had gradually become less frequent and less severe since he changed his occupation. During the period when he was still exposed to DMF, flushing episodes had also been associated with periorbital swelling, wheezing and dysgeusia. He had reduced exercise tolerance at this time and pulmonary function tests were abnormal (all expressed as a% of predicted value: FEV1 74%, FVC 85%, PEF 58%). He was not atopic and had not taken any medication known to cause flushing or bronchoconstriction; chest X-ray and total serum lgE values were normal.


Survey was conducted to gather information on potential adverse health effects of Mobile Phones, and Telecommunication Tower Base Stations in Nigeria. Data was sourced from two sampled populations. Firstly from the people living in close proximity to base stations, and secondly from cell phone users.Questionnaire was used to gathered information from 574 people on thirteen nonspecific health symptoms. Data obtained was presented and analyzed. The analysis shows that people living close to the based stations over a long period of time with or without cell phone, and also the heavy phone users with close proximity to the base stations are liable to have some potential health hazards, such as fatigue, sleep disturbances, headaches, feeling of discomfort, difficulty in concentrating, depression, memory loss, visual disruptions, irritability, hearing disruptions, skin problems, cardiovascular disorders, and dizziness.


We present cavity QED experiments with an Er:YSO crystal magnetically coupled to a 3D cylindrical sapphire loaded copper resonator. Such waveguide cavities are promising for the realization of a superconducting quantum processor. Here, we demonstrate the coherent integration of a rare-earth spin ensemble with the 3D architecture. The collective coupling strength of the Er$^{3+}$ spins to the 3D cavity is 21 MHz. The cylindrical sapphire loaded resonator allowed us to explore the anisotropic collective coupling between the rare-earth doped crystal and the cavity. This work shows the potential of spin doped solids in 3D quantum circuits for application as microwave quantum memories as well as for prospective microwave to optical interfaces.


The VISTA Variables in the V\'ia L\'actea (VVV) is a near-IR time-domain survey of the Galactic bulge and southern plane. One of the main goals of this survey is to reveal the 3D structure of the Milky Way through their variable stars. Particularly the RR Lyrae stars have been massively discovered in the inner regions of the bulge ($-8^\circ \lesssim b \lesssim -1^\circ$) by optical surveys such as OGLE and MACHO but leaving an unexplored window of more than $\sim 47$ sq deg ($-10.0^\circ \lesssim \ell \lesssim +10.7^\circ$ and $-10.3^\circ \lesssim b \lesssim -8.0^\circ$) observed by the VVV Survey. Our goal is to characterize the RR Lyrae stars in the outer bulge in terms of their periods, amplitudes, Fourier coefficients, and distances, in order to evaluate the 3D structure of the bulge in this area. The distance distribution of RR Lyrae stars will be compared to the one of red clump stars that is known to trace a X-shaped structure in order to determine if these two different stellar populations share the same Galactic distribution. We report the detection of more than 1000 RR Lyrae ab-type stars in the VVV Survey located in the outskirts of the Galactic bulge. Some of them are possibly associated with the Sagittarius Dwarf Spheroidal Galaxy. We calculated colors, reddening, extinction, and distances of the detected RR Lyrae stars in order to determine the outer bulge 3D structure. Our main result is that, at the low galactic latitudes mapped here, the RR Lyrae stars trace a centrally concentrated spheroidal distribution. This is a noticeably different spatial distribution to the one traced by red clump stars known to follow a bar and X-shape structure. We estimate the completeness of our RRab sample in $80\%$ for $K_{\rm s}\lesssim15$ mag.


The correlation matrixes are constructed based on the NCEP/NCAR global height field data and the surface pressure data and the characteristics of these two matrixes are analyzed.The results show that the correlations in all levels of height field are better in the middle-low latitudes regions and descend to the middle-high latitudes regions,presenting the characteristics of quasi-zonal distribution;in the vertical direction,the correlations in the low levels are weaker and become more and more stronger with the increase in height;and there is always a negative correlation center in all levels of height field in the north Pacific region,reflecting a certain degree of particularity.The results of the delayed correlation show that the correlation is decreased with the increasing in the delayed days,the change of correlation gradually flats when the delayed time is 15 days and there is an obvious turning point at the time of 60 days.The fact that the correlation decreased with the increasing in delayed days and existence of the decay critical point provide a theory reference for the numerical prediction of 2 weeks or longer time scale.The decay rate of correlation in the circulation system reflects the feature that the higher the latitude is and/or the lower the level is the stronger the correlation is.Changes over time in the global average correlations for the three height fields and the surface pressure field are almost the same with abrupt changes occurred during 1978-1982 and 1996-1998.


To date, our ability to speculate how species interactions will change temporally and spatially in response to WLR still inadequate, especially within large river-reservoir ecosystems. Fish communities in backwater bay of the Xiaojiang River of the TGR (Three Gorges Reservoir) were studied in 2010 and 2016 using a stable isotope approach to explore variations in fish trophic niches associated WLR. We found that fish assemblages tended to have broader trophic diversity spaces in LBAs (large backwater areas) at a water depth of 175 m, suggesting that the assimilation of food resources might come from a greater diversity of habitats or prey items with distinct isotopic signatures. Many among-fish species trophic niches tended to overlap and have broader ranges in LBAs compared to SBAs (small backwater areas) at a water depth of 145 m, which indicated that the processes of impounding at 175 m can provide more similar food resources for different fish species. Our findings highlight that WLR dynamics are typical characteristics of the backwater bay of the Xiaojiang River aquatic ecosystems caused by the operations of the TGR, which has significant ecological effects on the fish trophic structure within this community. Understanding the pattern of changes in fish trophic niche associated with WLR will be meaningful for fishery resources management of the other tributaries in the TGR.


This article presents a unified analytical solution for the analysis of thermal deformations and stresses in elastic annular disks with arbitrary cross-sections of continuously variable thickness. The annular disk is assumed to be under steady heat flow conditions, in which the inner surface of the annular disk is at an initial temperature and the outer surface at zero temperature. The governing second-order differential equation is derived from the basic equations of the thermal annular disks and solved with the aid of some hypergeometric functions. Numerical results for thermal stresses and displacement are given for various annular disks. These disks include annular disks of thickness profiles in the form of general parabolic and exponential functions. Additional annular disks with nonlinearly variable thickness and uniform thickness are also included.


Objective
To investigate the prevalence of human papillomavirus infection in women in Dongyang.

Methods
Cobas 4800 HPV detection system was used to detect 14 kinds of high-risk HPV genotypes from cervical scrapes of 15 978 women in Dongyang. And positive results of Cobas 4800 HPV were divided into HPV 16, HPV 18 and another 12 genotypes of high-risk HPV (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68).

Results
① HR-HPV DNA detection rate in the enrolled subjects was 15.4% (2 461/15 978); of the infected women, HPV 16 infection rate was 1.9% (303/15 978), HPV 18 infection rate was 0.6% (94/15 978) and infection rate of high-risk HPV of other 12 genotypes was 11.5% (1 830/15 978). Positive rate of mixed infection (no less than two genotypes) was 1.5% (234/15 978). ② In the 15 978 enrolled subjects, the positive rate of the age≤20 years old group was 40.3% (27/67), which was 16.8% (438/2 610) of 21 to 30 years old group, 13.8% (659/4 766) in 31 to 40 years old group, 13.8% (741/5 360) in 41 to 50 years old group, 18.8% (596/3 175) in the age >50 years old group (P=0.000). ③ The proportion of HPV 16 infection was 14.8%(4/27), which was the highest, among the HPV infected patients in the age≤20 years old group. The proportion of HPV 18 infection was 4.9%(29/596), which was the highest, among the HPV infected patients in the age>50 years old group. The proportion of HPV infection of other 12 high-risk genotypes was 76.8%(569/741), which was the highest, among the infected patients in 41 to 50 years old group. The proportion of mixed infection (no less than two genotypes) was 13.9%(61/438), which was the highest, among the infected patients in 21 to 30 years old group.

Conclusions
HR-HPV detection rate in Dongyang is higher than national average. The younger women have high infection rate among all ages.

Key words:
Cobas 4800; High-risk human papillomavirus; Cervical cancer


Abstract : Using a simple time dependent cold plasma density model and assuming a typical ambient radation belt environment, the authors study the evolution of the whistler mode turbulence and particle precipitation in a cold plasma release experiment similar to one which may be conducted as part of the AMPTE program. It is known from earlier work that the release of cold lithium ions can significantly lower the critical energy E sub c above which the resonant radiation belt electrons can pitch angle scatter. They study the time evolution of the one pass gain factor for a whistler wave packet and find that for parameters accessible to AMPTE type experiments the gain factor is large enough to ensure strong whistler turbulence and strong pitch angle diffusion of radiation belt particles with energies in the range between the ambient value of E sub c and the reduced value of E sub c. Estimates for the total power input to the ionospheric footprint of the release are of the order of an erg/sq cm/sec. This precipitated energy should produce a patch of visible aurora. This effect should also persist for many hours. (Author)


The results of epidemiological investigation of anaphylactoid shock prevalence in allergic and pseudoallergic diseases structure in Irkutsk, Angarsk and Meget are presented. All patients with anaphylactoid shock had accompanying gastro-enterological diseases and the low activity of hepatic monooxygenases system. The differential diagnosis criterions of anaphylactoid shock are suggested.


HERE is usually considerable variation among plant varieties T of a given species in reaction to temperature (6, 8, IO, 15),~ drought ( 5 , 16), disease (I, 9, IS), insects (3, 12, 13, 17), etc. It is likewise known that plant varieties react differently in the absorption and metabolism of at least some of the chemical elements. Such varietal differences have been noted by Anderson and Ayre (2), Burkholder and McVeigh (4), and Hoener and DeTurk (11) for nitrogen; by DeTurk, et al. ( 7 ) , Lyness (14), and Smith (18) for phosphorus; by Weiss (20) for iron, and by Allen4 for several of the major elements. Yamasaki (21) observed the differential behavior of rice and wheat varieties to copper sulfate, sodium arsenate, zinc chloride, mercuric chloride, potassium dichromate, potassium cyanide, potassium perchlorate, potassium iodate, potassium bromate, and potassium and sodium chlorate. From his experiments, he concluded that definite varietal distinctions existed only with respect to the chlorates and that the basis for this distinction is the differential ability of the plants to reduce the nontoxic chlorate ions to the toxic hypochlorite ions. With reference to the effect of the other chemicals tested for varietal reaction, Yamasaki (21) stated that, "All of the salts tested other than the chlorates, KClO, and NaClO,, injured the seedlings very seriously as a whole but never showed the varietal distinctions as observed in relation to KClO,." This statement is believed by the writer to be unjustified on the basis that Yamasaki correlated the results of an experimentally determined concentration of KClO, (0.2'37,) with those from an equal concentration of ZnC12, and concluded therefrom that the latter was incapable of inducing varietal distinction. Had he experimented as thoroughly with different concentrations of the other salts as he did with the chlorates, he probably would have discovered that varietal distinction to direct toxicants5 is a matter of salt concentration rather than salt specificity. The purpose of this paper, therefore, is to' call attention to the


In our study we describe further characteristics of a CD4+ T cell line (G‐05) isolated from lymph nodes of C3H/HeJ mice chronically infected with Trypanosoma cruzi. This T cell line secreted lymphokines such as interleukin (IL)4 and IL 5 and could be defined as a TH2 type of helper T cells. By passive transferinto naive mice, the G‐05 line was able to induce a polyclonal B cell activation in the spleen. This splenic B cell activation was quite similar to that seen in chronically T. cruzi‐infected animals, where the isotypic pattern presents a large increase of IgG2a and IgG2b isotypes. Moreover, it was possible to reproduce this kind of polyclonal B cell activation in vivo, with the supernatant of G‐05 T cells cultured in the presence of T. cruzi extract, accessory cells andexogenous IL2. Analysis of this supernatant showed the presence of large amounts of IL 4,IL 5, IL 3 and IL 6 but not of interferon‐γ, and residual IL 2 activity was not significant. These results suggest that the G‐05 T cells considered as TH2 cells on the basis of their lymphokine production are involved in the development of the in vivo polyclonal B cell activation in T. cruzi infection.


Conservative mayoral candidate and current City Hall incumbent, Boris Johnson, outlines his manifesto for Londoners with a focus on cutting waste, keeping London safer with officers on the beat and getting the best bargain from Downing Street. This post follows on from contributions earlier this week from other mayoral candidates including Brian Paddick, Ken Livingstone and Jenny Jones, with an introduction by Tony Travers


Scolopendra cingulata Latreille, 1829 is the commonest scolopendromorph species in the Mediterranean area. However, its orphological and geographic variation has not been examined so far, and therefore robust hypotheses about the factors that ave shaped that variability are lacking. We examined, using multivariate methods for 19 morphometric and meristic characters, he morphological variation of that species using a comprehensive sample of 503 adult specimens from 130 restricted geographic ocalities. The localities were distributed in three major geographic areas (Balkans, Asia Minor-Middle East, and Italy) in order o discern biological entities and to estimate the morphological relationships between populations and geographic regions. esults showed significant differences between the three geographic groups. Characters such as the distance between the aramedian sulci of the 7th and 8th tergite, the number of antennal segments, the number of spines on the dorsal side of 21st refemur and number of spines on the 21st prefemoral process significantly discriminated populations of S. cingulata along a est–east geographic gradient. Both eastern (Balkan) and easternmost populations (Asia Minor-Middle East) showed higher ean values of antennal articles and spines of 21st prefemur than the Italian populations. No significant morphological variation as discovered between the sexes of S. cingulata apart from cephalic width and distance between the two paramedian sulci of he 7th and 8th tergite. Based on certain morphometric differences among the three major geographic regions, we suggest that . cingulata originated in the east and colonized south European area from two different geographic routes. It is suggested that est–east morphological trend of S. cingulata is related either to the prominent palaeogeographic events of the area or to the ompetition with S. oraniensis Lucas, 1846 in the western Mediterranean. 2010 Elsevier GmbH. All rights reserved.


The fruit and vegetable sector must face major challenges arising from the concentration of demand in a few retail chains, the existence of an increasingly global and liberalised market, the growing demand for healthier products and adaptation to the successive reforms of the Common Market Organisation. Response to this series of problems has been to create closer ties between the production and handling/commercialisation phases, the introduction


Global and multinational corporations are increasing their overall use of logistics outsourcing, forcing corporate logistics organisations to focus on developing third-party management and governance capabilities, in addition to logistics functional expertise. What is interesting to note is that these corporations are also rationalising the global logistics providers they use at the same time.


. We give a translation of the entitled paper [Ant81]. We include an appendix that shows how to produce normal forms for each nilpotent orbit.


Climate vulnerabilities of the built environment are increasingly recognised. Mainstreaming adaptation concerns in urban development and redevelopment projects is commonly propagated as an effective policy strategy. Adaptation mainstreaming research often studies public actors. This article investigates the adaptation practices by housing associations, in the institutional and discursive developments of the social housing domain in which they are embedded. The analytical concepts of mainstreaming and adaptation barriers are combined with the discursive-institutional policy arrangement approach to answer the question: what factors influence the mainstreaming of climate change adaptation measures in development and renovation projects in the social housing domain in the Netherlands? We conclude that anticipatory and deliberate adaptation action to date was very scarce and attention limited in the social housing domain. On the project implementation level, factors that hampered adaptation mainstreaming in housing development were limited awareness, low priority in relation to other issues, financial constraints, regulatory constraints, lacking cooperation, and no materialisation of adaptation concerns in procedures and performance agreements. On the level of the policy arrangement, adaptation is weakly institutionalized in the Dutch social housing domain. The institutionalisation of a competing 'core activities' discourse hampered the legality of climate adaptation measures and eroded financial resources, dispersing the power to mobilise them over the arrangement. Uncertainty over the meaning of the new regulations, in combination with the absence of a comprehensive regulatory framework for adaptation and the self-identified culture of risk aversion by housing associations, delimits adaptation action becoming a standard operating procedure of social housing associations.


This paper contributes the new idea to the world of local search in computer science. The use of the local search is to provide the client with the most accurate information of source to destination. This paper enhances this idea and helps the client to reach its destination without any dilemma. This paper aims in providing the route to the client from source to destination with the alternative of three paths, one being the shortest distance then the other. Furthermore this paper also explains the use of local search via mobile, helping the client to reach its destination with the help of web mapping services.


With the implementation of Human Genome Project,Genomics and Proteomics has emerged,and developed rapidly.The contradiction between the complexity of object and the limitation of cognitive subject is the main motive force of science,which is the internal cause.International collaboration,government's support,enterprises and companies' devotion,development of bioinformatics and internet,attention from medium,which are the external cause.Internal and external cause form the system engineering to promote the science's progression.


It has been proven that the interactions or relationships established between humans and animals in livestock production significantly affect both. Therefore, it is extremely important that the quality of these interactions be positive and reflect a genuine sense of caring on the part of the people who deal directly with the animals. This study draws on some of the most important publications on the subject from 1986 to 2022 found in article databases; presents the main concepts used to understand the subject; lists the main reasons for what can be considered mistreatment of animals in animal husbandry (negative behaviours); and proposes solutions based on the literature and the author's experience. The purpose of this article is to help a) shift the paradigm and prioritise the definition of a personal profile that should work with animals, rather than focusing exclusively on the technical training of animal caregivers or on the common definition of "stockperson"; b) propose an analytical solution that can be applied during the recruitment process; and c) serve as a basis for the most relevant literature on the subject, given the already large number of publications, and d) encourage mutual reflection. Doi: 10.28991/SciMedJ-2022-04-03-04 Full Text: PDF


M.C., Costa M. & Cardoso M. 2004. (Prevalence of revalence of revalence of revalence of This study aimed to determine the prevalence of Salmonella positive pigs at slaughterhouses under federal inspection in Rio Grande do Sul, Brazil. Samples of feces and lymph nodes of 300 animals were collected in three different slaughterhouses, and submitted to bacteriological analysis. The prevalence of Salmonella carrier animals was 55.66%, being 17.6% of the animals Salmonella positive in lymph nodes, 18.3% in feces and 19.6% in both materials. Twenty-six different serovars were identified among 226 Salmonella isolates. The most prevalent serovars were: Typhimurium (24.3%), Agona (19.9%), Derby (13.2%) e Bredeney (12%). These results point out the need of control programs to reduce the prevalence of carrier pigs at slaughter.


Transactional memory (TM) was invented 15 years ago [1]. Recently, however, TM activity has exploded [2], as the proliferation of multicore chips has provoked researchers to revisit support for parallel programming. Since some regard me as a TM expert, most of my talk will summarize TM's goals and implementation options, primarily by developing a taxonomy and using Wisconsin LogTM [3, 4] as a case study. In particular, I will consider TM implementations via software, hardware, and hybrids, as well as important design choices, such as how to buffer TM writes and when to detect TM conflicts.

I will conclude with forward-looking comments regarding TM and database transactions. In theory, the two concepts have many similarities. In practice, however, they differ substantially. First, today's TM exclusively targets concurrency, while database transactions seek reliability first. Second, TM implementations focus in operations with caches and memory, while database transactions deal more with the more substantial access gap between memory and disks. Finally, I will speculate on cross-fertilization opportunities between TM and database transactions. I will not provide answers here, in part because you are the database experts. Nevertheless, I hope to encourage us all to ask the right questions.


Information security risk assessment is an important activity, which helps to explain risk exposure and to asset security need. However, on one hand, a lot of methods use the subjective measurements, which does not allow capturing accurate estimates. On other hand, application of the quantitative methods requires time and efforts. In order to mitigate their limitations, we discuss how to do some to combine both qualitative and quantitative methods for the security risk management. We illustrate this combination in the running example.


Abstract: With Globally Important Agricultural Heritage Systems (GIAHS) increasing in number around the world, their conservation has become a new international research theme. From the perspective of combining theoretical analyses and practical case applications, this study examines the Important Agricultural Heritage Systems (IAHS) conservation pathways and operation mechanisms through industrial integration development (IID). First, the theoretical framework of IID in IAHS sites was constructed according to the requirements of IAHS conservation, which include analyses of the connotation and basic principles of IID, the necessity of IID for IAHS sites, the resource conditions, and the IID pathways. And then based on the theoretical framework, the IID of Longji Terraces in Guangxi, Honghe Hani Rice Terraces System in Yunnan (HHRTS), Aohan Dryland Farming System in Inner Mongolia (ADFS), and Huzhou Mulberry-dyke & Fish-pond System (HMFS) in Zhejiang are analyzed systematically. The main finding is that IID is an effective pathway for IAHS conservation. However, the IID in IAHS sites must stress the ecological and cultural values of the resources; IID should be based on local resource advantages; and IID should attach importance to the combination of different policies and coordination between different stakeholders.


Pseudomonas aeruginosa and Ochrobactrum sp. were tested according to EPS production at different pH, temperatures, Remazol Blue concentrations, and incubation periods. Optimum pH was 7 for P. aeruginosa and 8 for Ochrobactrum sp. according to the highest EPS amount. P. aeruginosa produced the highest EPS (456.4 mg·l -1 ) after incubation for 48 h (40oC) and Ochrobactrum sp. gave the highest yield (404.6 mg·l -1 ) after incubation for 72 h (30oC). P. aeruginosa had a low capacity to remove Remazol Blue (12.5%); however, Ochrobactrum sp. had a significant potential to remove Remazol Blue yielded as 89.4%.


The weight of the brain in insane persons has been investigated by Dr. Parchappe in France, Dr. Bergmann in Germany, and on a larger scale, by Dr. Boyd in this country.∗ Further observations, however, were, for many reasons, to be desired; and having during many years past either weighed myself, or caused to be weighed, the brain of nearly every patient who has died whilst under my care, I ventured to think the large series of observations thus obtained, and which amount to 470 cases, were worthy of being collected, analysed, and compared with the weights recorded by previous observers.


Finds an issue going by default, namely that under the Evidence Act 2006, a statement is no longer hearsay if it was uttered by someone who gives evidence and is liable to cross-examination in the proceeding.


The dual carriageway viaduct structure has composite steel/concrete spans over the railway network, the approach spans are in-situ reinforced concrete, the whole is supported on 23 rows of columns. Constructed in 1957, the bridge had no waterproofing and inadequate detailing to control water run-off. Initial inspection in 1978 showed that reinforcement corrosion due to chloride attack was most severe in the column heads at the deck joints and the deck edges. A corrosion survey was carried out using principally electrochemical potential measurements and chloride drilling. The methods used and interpretation of results are described. The remedial work included removing twelve split hinged columns at the deck expansion joints and replacing with solid columns, the deck movement being taken by sliding bearings at the column head. Concrete columns supporting the steel/concrete portions of the deck were refaced. Treatment of steel handrails and parapet coping is also described. For working with restricted headroom a lorry-mounted lifting device was designed and manufactured. Further work which will be required is discussed. The need for design and construction of bridges to resist salt damage and thus prevent costly repair work is stressed. (TRRL)


Local festivals are increasingly being used as instruments for promoting tourism and boosting the local economy. But sometimes, some local festivals are criticized for having similarities, lack of characteristics. Recently local festival experts and media insist on merger and abolition of local festivals. This study tried to find out the reality of local festivals and opinion as to merger and abolition of local festivals in Gyeongnam. Most local residence approved of the merger and abolition of local festivals, but merger and abolition of local festivals have to be carried forward prudently. Finally, this study will be helpful for local festival manager to understand and operate of local festivals.


Within the current context of changing ecosystems, many organisms are experiencing phenological changes in the timing of migration. Here, we assessed whether the abundance patterns of two trans-equatorial migrating pelagic seabirds, the great shearwater and the sooty shearwater (Puffinus gravis and P. griseus, respectively), have changed over recent decades in the Bay of Biscay in relation to the main drivers shaping their migratory journey: climatic factors and food availability. Specifically, we studied the staging dynamic by estimating dates of arrival and departure, staging duration and abundance during a 16-year temporal window (1995-2010) based on monthly at-sea observations performed onboard a commercial ferry. Climatic effects were studied at two temporal scales: oceanic winds and global oscillations indices (North Atlantic Oscillation – NAO) that represent climate variability at short and long time scales, respectively. Based on oceanic winds, we also estimated a hypothetical cost of flying on a monthly basis considering wind speed and the angle between flight and wind direction. Our results showed that both great and sooty shearwaters were influenced by the large scale NAO index but the shape of the relationship was different, while the sooty shearwater was also influenced by food availability. Thus, each species might rely on different cues before and during their migration to adjust to optimal flying conditions and foraging grounds. Both species shape their arrival in the Bay of Biscay with periods of potential minimum flying costs, following their migration from the western to the eastern North Atlantic. We foresee that the quantification of flying costs can integrate different processes at the level of migration and provide a wider understanding of the migratory dynamic of pelagic predators within current changing ecosystems.


We study the dynamic behavior of a Neoclassical growth model with finite lifetimes and imperfect altruism in which individuals can accumulate both physical and human capital. We use the model to better understand and explain the behavior of economic miracles. Our results suggest that standard Neoclassical forces can account for the performance of the miracle economies and can explain the protracted transition that is inconsistent with the predictions of a Neoclassical set-up with only physical capital. The model is also consistent with the dramatic rise in investments in physical and human capital that these miracle economies experienced. ∗We thank NSF for financial support. Seshadri thanks the Alfred P Sloan Foundation for financial support.


Interference patterns in reflectance and transmittance of a thin platelet of CuCl in the Z 3 exciton region have been analyzed in terms of an extended version of the D' Andrea-Del Sole theory about microscopic treatment of additional boundary condition (ABC). In the extension, quantization effect has been explicitly considered with respect to exciton motion in a slab. The effect of internal multiple reflection of polariton waves and the energy dependence of exciton damping factor have been taken into account. The decay constant of the evanescent exciton wave near surface has been treated as an adjustable parameter. The observed spectra by Mita and Nagasawa are well reproduced by the simplest extreme case of this theory, i.e., the case of vanishing contribution from the evanescent wave, which is equivalent to the Pekar's ABC.


Gang-related criminal activity has become increasingly more sophisticated, taking advantage of technological advancements that have occurred during the past few decades. Among these advances, criminal gangs have begun to use the internet as an effective tool through which criminal activity can be conducted. Investigators must be adept and competent at locating and collecting gang-related evidence from the internet and from various electronic storage devices. Various techniques of investigation, the legal statutes associated with these types of investigations, and the legal parameters and limits when conducting these investigations are discussed.


Lipopolysaccharides (LPSs) were separated by SDS-PAGE, transferred onto polyvinylidene difluoride membranes, and hydrolyzed under acid conditions known to liberate lipid A from a broad variety of bacterial species. Independent of whether bis- or monophosphorylated lipid was set free, it remained bound to the membrane during subsequent immunostaining with monoclonal antibodies (MAbs) specific for the 1,4'-bis- or 4'-monophosphorylated lipid A backbone. Lipid A could be detected in the smooth (S)-form LPS from Enterobacteriaceae (Salmonella enterica, Citrobacter, Escherichia coli, Klebsiella pneumoniae, Serratia marcescens and Yersinia enterocolitica), Pseudomonas aeruginosa, Chromobacterium violaceum, Acinetobacter, Vibrio cholerae and Legionella pneumophila, thus allowing LPS-phenotype determination. The procedure can be used for the majority of Gram-negative bacteria, since LPSs containing 2,3-diamino-2,3-dideoxy-glucose or glucosamine in the lipid A disaccharide backbone could be detected. It was shown to be sensitive (up to 20 ng of hydrolyzed LPS could be detected), and could be easily performed using isolated LPS or whole-cell lysates with or without prior digestion with proteinase K. In addition to opening several other application possibilities, the procedure may be particularly useful in cases where silver-staining of the O-chain in SDSpolyacrylamide gels fails and specific antibodies against the O-antigen are not available.


A simple, descriptive and interpretable model, based on a quantitative structure-retention relationship (QSRR), was developed using the genetic algo- rithm-multiple linear regression (GA-MLR) approach for the prediction of the retention indices (RI) of essential oil components. By molecular modeling, three significant descriptors related to the RI values of the essential oils were identified. A data set was selected consisting of the retention indices for 32 essential oil molecules with a range of more than 931 compounds. Then, a suit- able set of the molecular descriptors was calculated and the important descrip- tors were selected with the aid of the genetic algorithm and multiple regression method. A model with a low prediction error and a good correlation coefficient was obtained. This model was used for the prediction of the RI values of some essential oil components which were not used in the modeling procedure.


In this second feature on American developments, David Rogers looks at convenience stores, electronic retailing, department stores and children's clothing.


In view of the fuzziness and randomness of groundwater quality evaluation and the rationality and scientificityof the weight in the evaluation process, in order to establish an objective, scientific and convenient mine waterenvironment evaluation system and improve the accuracy of the evaluation results, AHP and EWM weight method arecombined to obtain the weight value, which is coupled with Bayesian water quality evaluation model. In this paper, sevenwater quality evaluation factors and ten groups of water samples are selected to analyze the application of mine water inShengquan coal mine, Shandong Province. At the same time, the single factor evaluation method, equal weightBayesian model and fuzzy comprehensive evaluation method are used to compare with the evaluation results to verifythe accuracy of the evaluation results of the model. The results show that the water quality evaluation model ofcombined weighted Bayesian model is reasonable for mine water quality evaluation, which not only distinguishes thedifference of each evaluation factor's contribution to water quality, but also makes a more accurate evaluation of waterquality, and the calculation process is simple, which avoids the complexity of multiple indicators of traditional methods,and provides a scientific basis for comprehensive utilization of mine water in mining area, so the evaluation method ispractical.


Personalizing the learning process through mentoring-transcript programs can enhance the individual growth of educators as well as students and contribute to the revitalization of postsecondary institutions.


Large quantity and high efficient spinning technology can decrease investment of fixed assets such as equipment and factory place and save time.It also can assure the product quality,so people pay more and more attention to it.Through experiments on this technology,this paper gives the attentions and countermeasures in selecting large quantity and high efficient spinning technology and conditions.


The present paper describes the design, implementation and evaluation of a web-based tool for aiding in teaching in some experimental technical subjects. Two main concerns have been considered during the design: to reproduce as accurately as possible the experimental teaching process, training the students for the "real experience", and to be extremely easy to manage by the teachers, in order to require minimal computer skills to prepare, publish and monitorize the experiments. Therefore, the system considers the access to the information related to each experiment —theoretical basis, instrumentation, required tasks, simulations, etc.—, as well as some teaching aids which try to mimic the normal behaviour of the students-teacher relationship —messaging, phorums, etc.—. The system has been applied to a laboratory of Electromagnetism and the evaluation by the students has shown a positive response.


A method for providing a lotto game package is provided to enable a divided lotto package seller to satisfy buyer's desire wanting to increase winning probability by providing the divided lotto game packages of the lotto game package. Lotto game package information comprising a plurality of lotto games is generated(300), and the lotto game package information is provided to more than one client terminal through the wired/wireless network. A betting type purchase request for each lotto game is received from the client terminal(325). Payment for the lotto game packages is processed according to lotto game package request information(325). Lotto game package purchase details and betting details of each lotto game are stored to a database by linking with client information(345). Winning money is paid to the client based on the lotto game package purchase details and the betting details when winning of the lotto game is checked(360).


Summary We give five proofs that the coefficients in the nth derivative of exp(1/x) are the Lah numbers, a triangle of integers whose best-known applications are in combinatorics and finite difference calculus. Our proofs use tools from several areas of mathematics, including binomial coefficients, Faà di Bruno's formula, set partitions, Maclaurin series, factorial powers, the Poisson probability distribution, and hypergeometric functions.


In addition to photoperiod, thermoperiod (or thermocycle) might be an important Zeitgeber for entraining the circadian oscillator controlling adult eclosion rhythm in the Indian meal moth Plodia interpunctella Hübner (Lepidoptera: Pyralidae). This is confirmed by exposing larvae receiving diapause‐preventing treatments to various thermocycles with different means and amplitudes of temperature. The thermocycles investigated in the present study are TC 8 : 16 h, TC 12 : 12 h, TC 16 : 8 h and TC 20 : 4 h, where T and C represent thermophase (30 °C) and cryophase (20 °C), respectively. For all thermocycles, the peak of adult eclosion rhythm occurs at around the mid‐thermophase. This indicates that the larvae use both 'temperature‐rise' and 'temperature‐fall' signals to adjust the eclosion phase in each thermocycle. The absence (DD) or presence (LL) of light affects this time‐keeping system slightly under the given thermocycle. The rhythmic adult eclosion noted after exposure of larvae to 30 °C DD for 14 days is recorded in the thermocycles (TC 12 : 12 h, DD; mean temperature = 25 °C) with different amplitudes of 27.5/22.5 °C, 26.5/23.5 °C and 25.5/24.5 °C. The peak in adult eclosion advances in time as the amplitude of the temperature cycle decreases. In the temperature cycle of 25.5/24.5 °C, a peak occurs at the end of the cryophase, 2 h before the temperature‐rise. The adult eclosion rhythm is also observed under various thermocycles (TC 12 : 12 h, DD) consisting of different temperature levels (30 to 20 °C) with different amplitudes. It is found that the temporal position of the peak advances significantly when the amplitude of the thermocycle becomes lower.


Fire extinguishing apparatus comprises a housing defining a first chamber containing the gas generating agent. Device is combined operably with the first chamber, further comprising an initiator in communication with relation to initiate the reaction with the gas generating agent. Initiator, ignites at least a portion of the gas generating agent functions to form a gas during operation. The housing defines a further second chamber disposed adjacent to the first chamber. The second chamber houses a material that can be changed by endothermic reaction, and a piston assembly including a piston. In operation, the piston is moved to eject at least a part of the material can be changed by the endothermic reaction from a second chamber, as a result, materials that can be changed by an endothermic reaction which is discharged is, gas in contact with the gas formed by ignition of the generator cooling the gas. The housing further comprises at least one release hole in order to be able to issue a cooled gas from the housing. Extinguishing method corresponding or related fire is also provided. .FIELD 1


This study examines pay reward system management and staff performance in Nigeria: using the Delta sate civil service as a focus. The data utilized in this study were obtained from both primary and secondary sources. While the primary data were derived from focus group discussions, the secondary data were obtained from relevant textbooks, journals and government documents. The findings of the study indicate that the incongruence of the pay reward system of the Delta state civil service and the central guiding principles of fairness, costs of living and moderation, the in-grained culture of poor performance and the dysfunctional employee mode of entry have negatively impacted on the performance of staff. The study made some useful recommendations including the exigency of a fair, moderate, dynamic pay reward system that should be reflective of the prevailing societal costs of living, the dismantling of the culture of poor performance and a merit-based employee entry practice. Key words: Pay Reward System, Management, Staff Performance, Nigeria


The differential capacity of iron oxide microspheres and of gadolinium‐diethylenetriamine pentaacetic acid (Gd‐DTPA) to serve as contrast agents that can map the microcirculation of MCF7 human breast cancer implanted in nude mice has been examined by high resolution MRI. Modulation of signal intensity in T2*‐weighted, gradient‐echo images after iron oxide administration and the temporal signal enhancement after Gd‐DTPA administration were monitored and analyzed at a spatial resolution of 98 × 98 × 500 μm and 195 × 390 × 1,000 μm, respectively. The pathophysiologic features revealed in the contrast‐enhanced images were analyzed in reference to those obtained from the corresponding high resolution T2‐weighted, spin‐echo images and from histologic sections stained with hematoxylin and eosin and with an endothelial cell marker. The results showed that iron oxide microspheres can aid in the characterization of gross histopathologic features and in the assessment of the distribution of the microvasculature, whereas Gd‐DTPA estimates the permeability of the microvessels to this agent and determines the cellularity (cell volume fraction) in the vicinity of the vessels.


As an important measure of domestic agricultural, the Direct Subsidies of Grain can accelerate the grain input and output. However, it conceals the environment cost which can not be ignored and will threaten the ecological environment. Under WTO framework, we should take comprehensive efficiency as the basic principle of direct subsidies of the grain to ensure the overall level and to improve the comprehensive efficiency of the domestic grain support.


Abstract A statistical model for life-lengths of structures under dynamic loading is derived. The model makes it possible to express the probability distribution of life-lengths in terms of the load given as a function of time and of deterioration occurring in time independently of loading. The special case of a constant load (or of periodic loading with constant amplitude) leads to gamma distributions for life lengths.


Along with the development of the science, the communication technology has already developed from the traditional air to the outer space and submarine. So, the UAC is getting more and more attentions from the researchers for its business and military value. However the local hydrology environment and the weather must be considered when the actual UAC experiments are carried and the experimental cost is so expensive that it is hard to carry on enough experiments[1]. What's more, There isn't a software that can compare all these algorithms conveniently, although there are many algorithms nowadays for UAC[2]. This paper studies to construct a software which can combine many algorithms and compare them in one unified frame. Also the software can help us design actual experiment system to obtain more valuable data in limited time.


Significance Exercise is a powerful anti-aging intervention. In muscle, exercise remodels mitochondrial metabolism and connectiveness, but the role of dynamic mitochondrial remodeling in exercise remains unknown. Using Caenorhabditis elegans, we find that the dynamic cycle of mitochondrial fission–fusion is critical for physical fitness. Exercise induces remodeling of the proteome that depends upon mitochondrial dynamics and delays an aging-associated decline in mitochondrial connectiveness and physical fitness. AMPK, a metabolic regulator that senses low energy availability and controls mitochondrial dynamics, is needed for exercise to maintain physical fitness with age and can recapitulate this exercise benefit. Our data identify the mitochondrial dynamics cycle as an essential mediator of exercise responsiveness and an entry point for interventions to maintain muscle function during aging.


The kinetics of the polymerization of lactic acid oligomers (LAO) was studied for the first time at various microwave irradiation powers (MW) in the presence of Sn(Oct)2/benzyl alcohol (C6H5CH2OH) catalyst and toluenesulfonic acid (TSA). LAO was polymerized in a multimodal reactor in a vacuum while sparging with nitrogen at powers of 130, 280, 360 W. The optimal concentrations of catalysts and initiator were determined, which represent 0.03 % Sn(Oct)2/C6H5CH2OH and 0.3–0.4 % TSA by weight of LAO. It was established that the polymerization of LAO in the presence of TSA proceeds already at 130 W. As the MW power increases, the rate of LAO polymerization increases. When Sn(Oct)2/C6H5CH2OH was used as a catalyst, the LAO polymerization process proceeds at a noticeable rate at 280 W, and after 25 min the molecular weight was about 20,000 Da. During the polymerization of LAO in the presence of catalysts at 360 W, lactide forms along with the formation of polylactic acid (PLA). Using the methods of IR and NMR spectroscopy, the structure of the obtained substances was studied. The synthesized PLA samples are optically pure; the optical rotation angle is 156–158 degrees×ml/dm×g. It has been suggested that during LAO polymerization under MW conditions, the so-called «non-thermal microwave effect» is observed, that is, at the same temperature (215 °C), but at different powers (280 W and 360 W), the LAO polymerization proceeds at different rates.


I argue that it is hard to distinguish between public relations and much of modern politics in the UK and that an important part of this conflation is a thoroughly bad thing. The working styles and job contents of spin doctor, lobbyist, event manager, corporate re-brander, special adviser and politician are merging, and making the distinctions of former, less presentationally conscious times harder to grasp. The merging has been given the mightiest of shoves by the behaviour of New Labour and has been much encouraged by the Mountfield Report (1998) on government communications.


Both world oil production and world's known oil reserves increase persistently year after year. These increases come mainly not from new oil-producing regions but from further development of long-established regions constituting only a small fraction of the world's prospective oil territory. Many of the remaining regions have not yet been adequately reconnoitered, so odds still strongly favor additional highly productive discoveries. However, already indicated variations in oil endowment suggest also that many regions will always remain barren or poorly productive even though apparently possessing all superficial requisites. Mere sedimentary volume is no index of oil potentiality. Moreover, even presence of adequate source, reservoir, cover, and traps may be nullified by he factor of timing.


Novel and robust algorithm for face detection and tracking is presented.Moving regions are extracted based on background subtraction at first.Candidate face regions are extracted according to skin-color normalized RGB and HSV color model based on the ex- tracted motion region.Face information with certain size and some holes is used to verify the face candidates.The facial region is tracked and estimated based on skin color moment characteristics.The experimental results have shown that the proposed method not only attains high face detection rate,but also is robust to illumination and face pose variations.The processing speed is about 25f/s on an average across 480×360 images,which meets the demand of real time system for face detection and tracking.