This article discusses the Qu'ran from the perspective of the Kejawen Islamic community and its implications in the lives of praxis. This research is a type of field research with the theory of social construction from Peter L. Berger that emphasizes the meaning and a shared-interpretation constructed in community networks. The results showed that the syncretic Kejawen Bonekeling Islamic community had its own views and beliefs about the Qur'an, not as a way of life like Muslims, but as a holy book that would be asked by angels in the grave. This view has implications for their lives. They understand the teachings of Islam in the Qur'an, such as prayer and aurat, different from Muslims in general. Prayer as sembahyang is interpreted as doing good to fellow human beings, getting along well, helping each other to help and protect the traditions of their ancestors. While regarding aurat, they do not have boundaries that must be covered, but they emphasize that the most important thing is to improve themselves first to become a good human being


The current study aimed to evaluate the role and gene target of miR-126 in Iraqi patients with Coronary Artery Disease (CAD) and atherosclerosis (AS). By coverage average age (35 to 65) years old of both genders, a total of 40 patients with CAD and 40 healthy people as a control group were enrolled in this clinical study. The blood samples of patients were taken from Ibn Al-Bitar Diagnostic Center for Heart Surgery in Baghdad/Iraq in December 2020 to April 2021. Overall, the CAD patients had significantly higher (except HDL) total lipid profile (total chol., total Trig., LDL, and VLDL, age, and IL6 levels). Statistically no significant correlation was found between miRNA-126 and lipid parameters in all studied subject. The correlation was found between Triglycerides and his-Troponin (r=-0.521, pv=0.032). The ROC analysis of mRNA126 at UAC 0


SUMMARY In order to enhance the brain-specific delivery, in this study we developed a targeting carrier system, which consists of CPEGGMPDSGM polymersomes with the conjugation of des-octanoyl ghrelin. To qualitatively and quantitatively investigate this carrier's properties, Cy5.5 and met-enkephalin were individually encapsulated in these polymersomes. Our results indicate that desoctanoyl ghrelin-conjugated polymersomes is a highly promising drug carrier for brain delivery, especially for peptide drug accessible to the central nervous system (CNS), since most peptides with considerable potential in the treatment of CNS diseases are susceptible to endopeptidases and hold a poor passage across the BBB. INTRODUCTION The effective protection of the BBB from tight junctions and efflux transport systems ultimately results in the limited entry of 95% of drug candidates, which are potentially beneficial for CNS diseases. The concentration in human plasma for endogenous des-octanoyl ghrelin is much lower than endogenous lactoferrin. This low concentration in plasma can effectively avoid the competitive inhibition to des-octanoyl ghrelin conjugated drug carrier system. Furthermore, des-octanoyl ghrelin was observed to transport only in the blood-to-brain direction and this can result in a higher accumulation of the conjugated carriers in the brain. The main objective of this study is to develop a polymersomal drug delivery system that can target the endothelial cells of the BBB and cross over it more effectively. EXPERIMENTAL METHODS The PGA (2g) with the NHS (1.8g) in the DMSO/pyridine mixture solution stirred, using DCC (3.2g) as an coupling agent. The PGNHSPDSGM (2g) was subjected to partially transesterification with the alpha-Aminoomega-carboxyl poly(ethylene glycol) hydrochloride (1.2g) in the DMF, with TEA (1.2mL) added. The stock solution of desoctanoyl ghrelin peptide was prepared in the DMSO solution. The CPEGGMPDSGM copolymer was dissolved in DMSO solution and incubated with EDC and NHS. The solution of des-octanoyl ghrelin peptide was then added to the activated CPEGGM-PDSGM solution. Desoctanoyl ghrelin-PEGGM-PDSGM (0.3g) and Cy5.5 (0.03g) were dissolved in a mixture THF and chloroform. The copolymer solution was then injected slowly into phosphate buffer under sonication with mild stirring to induce polymersomes self-assembling. Met-enkephalin (0.1 g) was dissolved in a phosphate solution to give a drug solution with 100 mg/mL in concentration. Des-octanoyl ghrelin-PEGGMPDSGM (0.35g) was placed in a ZrO2 mortar and mixed with a met-enkephalin solution (0.5mL). The mixtures were ground in the planetary ball mills to form a sticky paste. The paste was then placed in a flask and weighed. The phosphate solution was added to the flask to form a suspension of polymersomes encapsulated with met-enkephalin. RESULTS AND DISCUSSION This animal test model exhibited an earlyphased pain induced by the central nervous system and a late-phased pain by the central and the peripheral nervous system. Suppression of the early-phased pain reveals that the drug has an analgesic effect on the central nervous system. If the total licking duration was short, the analgesic effect of the drug was promising. Fig. 1 shows the results of antinociceptive effects for GPE, PE, saline and met-enkephalin solution after an intravenous injection for mice. It can be seen that both saline and metenkephalin solution did not reduce the nociceptive response of mice. The results also show that the licking duration of early and late phases for the GPE group is 2.7and 2.4-folds analgesic potency of those for the PE group, respectively. These data indicated that GPE could better deliver met-enkephalin across the BBB to the central nervous system. Fig. 1. Antinociceptive effects of saline, metenkephalin (Enk), PE and GPE on male ICR mice determined by formalin test after an i.v. injection with a dose of 15.0 mg/kg met enkephalin. In Fig. 2, in-vivo fluorescence image of GP5 versus P5 at different time points showed that the fluorescence intensity of GP5 in the brain was stronger as compared to P5 and the maximum fluorescence was observed at 60 min after administration. The intensity of GP5 was 2.3-folds as compared with that of P5. The fluorescence intensity of brain decreased about 120 min after injection and the decrease of fluorescence in brain with time might be explained by increased elimination of polymersomes from the body with time. The results provide strong evidence suggesting that des-octanoyl ghrelin-conjugated nanocarrier was able to deliver more Cy5.5 fluorescence to the brain than non-conjugated nanocarrier. Fig. 2. (1) In-vivo fluorescence images and (2) temporal responses of the region of interest in brains for the mice treated with P5 or GP5. CONCLUSION In conclusion, the des-octanoyl ghrelinconjugated polymersomes shows great potential in targeted drug delivery across the blood brain barrier, leading to a significant higher in-vivo brain accumulation. Our results indicate that des-octanoyl ghrelin-conjugated polymersomes is a highly promising drug carrier for brain delivery. REFERENCES 1. Tschöp, M.; Weyer, C.; Tataranni, P.A. Diabetes 2001, 50(4), 707-709. 2. Talukder, M. J.; Takeuchi, T.; Harada, E. J. Vet. Med. Sci. 2003, 65(9), 957-964. 3. Banks, W. A.; Tschöp, M.; Robinson, S.M.; Heiman, M. L. J. Pharmacol. Exp. Ther. 2002, 302(2), 822-827. Acknowledgments This work was supported by the National Health Research Institutes (No NHRI: ME-101PP-13) and the National Science Council of Taiwan (No NSC: 1012221-E-002-015-MY3).


In recent years,under the influence of global financial crisis,the molybdenum supply and demand condition has undergone profound changes.The price presents to oscillate to circulate a situation.By analyzing the supply and consumption situation in the world,movement regulation and impact factor of molybdenum price were found,and the molybdenum market trend in the world was pointed out.


Postnatal subventricular zone (SVZ) neural stem cells generate forebrain glia, namely astrocytes and oligodendrocytes. The cues necessary for this process are unclear, despite this phase of brain development being pivotal in forebrain gliogenesis. Galectin‐3 (Gal‐3) is increased in multiple brain pathologies and thereby regulates astrocyte proliferation and inflammation in injury. To study the function of Gal‐3 in inflammation and gliogenesis, we carried out functional studies in mouse. We overexpressed Gal‐3 with electroporation and using immunohistochemistry surprisingly found no inflammation in the healthy postnatal SVZ. This allowed investigation of inflammation‐independent effects of Gal‐3 on gliogenesis. Loss of Gal‐3 function via knockdown or conditional knockout reduced gliogenesis, whereas Gal‐3 overexpression increased it. Gal‐3 overexpression also increased the percentage of striatal astrocytes generated by the SVZ but decreased the percentage of oligodendrocytes. These novel findings were further elaborated with multiple analyses demonstrating that Gal‐3 binds to the bone morphogenetic protein receptor one alpha (BMPR1α) and increases bone morphogenetic protein (BMP) signaling. Conditional knockout of BMPR1α abolished the effect of Gal‐3 overexpression on gliogenesis. Gain‐of‐function of Gal‐3 is relevant in pathological conditions involving the human forebrain, which is particularly vulnerable to hypoxia/ischemia during perinatal gliogenesis. Hypoxic/ischemic injury induces astrogliosis, inflammation and cell death. We show that Gal‐3 immunoreactivity was increased in the perinatal human SVZ and striatum after hypoxia/ischemia. Our findings thus show a novel inflammation‐independent function for Gal‐3; it is necessary for gliogenesis and when increased in expression can induce astrogenesis via BMP signaling.


It is for the first time that a problem of cultural relations in the history of one of the most significant monuments of Petersburg Michailovsky Castle since its foundation up to nowadays is considered in this article. "A dialogue of cultures" was brightly revealed in the history of designing of this monument, its architectural image being shaped under the influence of the best samples of European architecture. The article contains analysis of the prototypes of the favorite residence of Paul I and evaluation of both the role of European traditions in the system of its ceremonial decoration and the extent of participation of European craftsmen in it. All that as well as West-European works of art abundantly introduced into decoration of the palace interiors, and especially the fact of conversion of the Emperor''s residence into a seat of the great grandmaster ofMaltese order make it possible to speak about Michailovsky Castle as of a monument of European culture in the broad sense of the word.


Over the past few years there has been increased interest in semantic technology as a foundation for metadata registries (MDR) in general and clinical data standards in particular. In this paper we will introduce the principles of RDF and Linked Data, and show how they can be applied to metadata management. We also highlight its role in a number of projects and initiatives, such as the Roche MDR for clinical data standards, the FDA/PhUSE Semantic Technology project, and a number of public initiatives. Of particular interest may be the use of RDF to represent CDISC standards such as SDTM and how RDF is well positioned to represent and link different types of metadata related to domains, variables, controlled terminology, and validation checks.


As a result of increased human lifespan, dementia becomes a national public health and social care priority worldwide. Although, there is no cure for dementia, the wandering behavior of dementia patients can be managed by an ambient assisted living system. In this paper, Wandering Behavior Ontology (WBO) used for dealing with wandering behavior seen in early stage dementia patients is proposed. WBO is used in iCarus, which is an intelligent ambient assisted living system, for providing context-aware services to dementia patients and their caregivers. Knowledge sharing, knowledge reuse and logical reasoning are provided by using ontologies. iCarus aims to reduce the problems and financial burden associated with a wandering episode for the patients and their caregivers. It provides longer independent living for the elderly people and a cost-effective way of remotely monitoring them. The actions that are to be taken are determined by rule-based reasoning. These actions are sequential and they are defined in the developed ontology. These actions include warning the patient and informing the caregiver and the emergency service.


The ability to recognize student composing as creative is central to supporting students' creative development as writers and meaning makers. Teachers who are able to recognize creativity in student compositions can play an important role in supporting their development as creative composers. The way that teachers conceptualize creativity, then, is crucial, since our conceptions of creativity affect how we recognize creativity in our students' work. Creativity is often perceived as a possession of a few who have been born with inherent creative abilities (Banaji & Burn, 2007). This perspective mystifies creativity, leaving students' creative writing and multimodal composing processes to go unrecognized and unsupported. However, Vygotsky's (1950/2004) discussion of an "everyday idea of creativity" (p. 10) offers a different perspective, and a very useful one for teachers:Creativity is present, in actuality, not only when great historical works are born but also whenever a person imagines, combines, alters, and creates something new, no matter how small a drop in the bucket this new thing appears compared to the work of geniuses. (p. 11)This conception of everyday creativity is important. It helps us understand that creativity is not just a privileged ability that some students have and others don't; it emphasizes that we all exhibit acts of creativity throughout our everyday lives and in many different ways. In this column, I will develop the concept of everyday creativity by exploring sociocultural theories of communication and thought that describe how individuals draw upon elements of their material and social environments in the making of signs and meanings (Bakhtin, 1935/1981; Vygotsky, 1950/2004, 1978). Central to this perspective is the idea that our thoughts, ideas, ways of understanding, and means of expression-as well as our creative acts-originate from our social interactions and participation in culture and everyday life. This sociocultural perspective on creativity and student composing comes with the assumption that "children's culture needs a much more central place in explorations of childhood and creativity" (Marsh, 2010, p. 50). A sociocultural perspective on creativity conceives of student composing as a complex process in which the creator draws upon previous experiences, events, and contexts as sources of meaning, which are then creatively put to new uses in the text being composed (Banaji & Burn, 2007; Marsh, 2010; Pahl, 2007; Ranker, 2007; Walsh, 2007). Banaji and Burn summarize a sociocultural perspective on creativity as follows:For the purposes of teasing out some relationships between media literacy and creativity, then, the most productive approaches to invoke are likely to be the culturalist and cultural psychology approaches. These have the advantages of emphasizing cultural contexts and resources, of theorizing the social development of identity and of providing a dialectical account of how imaginative work, play, and intellectual development together make up the creative process. (p. 67)I draw upon this sociocultural perspective on creativity to consider the question of how to recognize creativity in student writing and multimodal composing. From this perspective, at its center, creative composing is a process of creating new combinations of images, ideas, and other composed elements. Thus, creativity can be seen not as some mysterious process, but instead as the creator's process of transforming and assembling images, ideas, experiences, and events, and then recombining them into a new, creative whole. Following from this, I will also discuss how our conceptions of "originality" factor into teachers' recognition of student creativity.We often look for originality in highly unusual and never-before- seen types of compositions. However, from a sociocultural perspective on creativity, students can fashion highly original compositions by "redesigning" (New London Group, 2000) or "orchestrating" (Kress, 2010) seemingly ordinary and everyday aspects of their experiences and ideas. …


Exponential smoothing methods are widely used for forecasting demand because they are very efficient and easy to apply. Holt Winters algorithm can be classified into Additive and Multiplicative seasonal Variations. In this algorithm there are three smoothing parameters associated with level, trend and seasonal factors. Among the seasonal variations Multiplicative method is the widely used for forecasting purposes as it works better than additive in most of the cases. The problem lies when the data series contains some values equal to zero, then the multiplicative HW algorithm cannot be applied. In this paper we propose an improved additive HW method and we treat the initial values for the level, trend and seasonal components as well as three smoothing constants as decision variables. The presented new method is applied to the rainfall dataset and comparisons with other methods are made on this case study data.


The invention discloses a safe and environment-friendly oil refining technology achieving cracking recycling of waste organic matter by means of continuous feeding and slag discharging.The waste organic matter is sequentially treated with a stock bin, a crushing device, a magnetic separator, a drying device, a cracking catalyst stock bin, a constant-temperature efficient auger-type liquid heat-conducting medium heating device, a heat-conducting medium heating device, a liquid adsorption-type gas dedusting device, a carbon black collecting device, a catalytic restructuring device, a first-stage constant-temperature gas-liquid separation device, spray devices, high-temperature heat exchange devices, oil product neutralization devices, impurity filtering devices, finished product collecting devices, a second-stage gas-liquid separation device, a room-temperature gas-liquid separation device, an oil-water separation device, a tail gas treatment device, a tail gas recycling device, a waste water treatment device and a safety pressure relief device.By means of the safe and environment-friendly oil refining technology, the full set of functions from recycling to production oil refining of the waste organic matter can be achieved, continuous operating of the whole set of the functions is guaranteed, and therefore the production efficiency is greatly improved, and the production technology is optimized.


The increasing use of Social Media has transformed them into valuable tools, able to provide answers and decision support in public policy formulation. This has resulted in the emergence of new e-participation paradigms, such as crowdsourcing approaches, aiming to drive more constructive interactions between governments and citizens or experts, in order to exploit their knowledge, opinions, and ideas when tackling complex societal problems. However, the continuous exposure of the average users, without or with limited awareness of the dangers of the disclosure of sensitive data, remains a threat to the preservation of their information privacy. The upcoming EU General Data Protection Regulation (GDPR) about the protection of personal data is especially well timed, and forces for revision of the processes followed related to the manipulation of personal data within public participation methods. Towards this direction, a thorough examination of three advanced methods of crowdsourcing in public policy-making processes is conducted in the current paper, analysing the data collection and processing methods they encompass. Then, an assessment of their compliance with fundamental privacy requirements is presented. The research contributes to the identification of challenges that crowdsourcing, and in general, e-participation approaches impose with regard to privacy protection. Further research directions include the implementation of techniques that can satisfy the identified requirements.


The characteristics of the ion source determine the writing soeed and resolution that can be realized in direct writing ion beam lithography with focussed ion orobes. We have developed an H2+ ion source with very high brightness and low energy snread.1 Two ion beam lithography systems based on this source are being develoned. CAD has been used to design two ion optical-deflector systems to focus this source to high resolution, high current density Probes. The desicn narameters are calculated to produce ion probes 10 to 50 nm in diameter with current densities 100 amn/cm2. The systems will be use 1. to investigate and a' my ion beam lithogranhy: ion-resist interactions, resist eNnosure and develonment characteristics, resolution limits, ion beam structuring of devices, etc.


The format of the Chernorizec Hrabar Math Tournament includes 5 divisions for students of two consecutive grades, e.g. 5th and 6th grade students. A natural question is how appropriate is the common competition paper for any of two age strata. To clarify this issue we introduce the notion of age-factor index as the difference of the test-item difficulties calculated separately for any age stratum, e.g. ∆ = T k 5 − T k 6 where T k 5 and T k 6 stand for the test-item difficulty of the k-th test item for the 5th and 6th grade students' variation row respectively. The average value of ∆ for the contest paper could be considered as a relative measure of reliability and uniformity of the contest paper for a particular target group. The study presents details about 2015 Chernorizec Hrabar contest paper for 5th and 6th graders and the application of the new concept in didactical analysis.


This study presents the results of training designed to enhance students' awareness of gender consciousness and gender attitudes in counseling. The participants were 49 master's degree students (19 male; 30 female; average age, 34 years). We adopted the methodology of action research and took a feminist standpoint. Five focus-group interviews were conducted with students to discuss and share what they learned from the new 'Gender and Counseling' unit. The results suggest that some graduate students were able to accept gender pluralism, some expressed astonishment at being in contact with lecturers, and others displayed the profound influence of traditional Chinese culture and insisted that gender pluralism breeds social unrest. © 2016 Published by Future Academy www.FutureAcademy.org.uk


Introduction: Skeletal homeostasis is normally maintained by the stability between bone formation by osteoblasts and bone resorption by osteoclasts. However, the correlation between the inflammatory reaction and osteoblastic differentiation of cultured osteoprogenitor cells has not been fully investigated. This study examined the effects of inflammatory cytokines on the osteoblastic differentiation of cultured human periosteal-derived cells. Materials and Methods: Periosteal-derived cells were obtained from the mandibular periosteum and introduced into the cell culture. After passage 3, the periosteal-derived cells were further cultured in an osteogenic induction Dulbecco's modified Eagle's medium (DMEM) medium containing dexamethasone, ascorbic acid, and β-glycerophosphate. In this culture medium, tumor necrosis factor (TNF)-αwith different concentrations (0.1, 1, and 10 ng/mL) or interleukin (IL)-1βwith different concentrations (0.01, 0.1, and 1 ng/mL) were added. Results: Both TNF-αand IL-1βstimulated alkaline phosphatase (ALP) expression in the periosteal-derived cells. TNF-αand IL-1βincreased the level of ALP expression in a dose-dependent manner. Both TNF-αand IL-1βalso increased the level of alizarin red S staining in a dose-dependent manner during osteoblastic differentiation of cultured human periosteal-derived cells. Conclusion: These results suggest that inflammatory cytokines TNF-αand IL-1βcan stimulate the osteoblastic activity of cultured human periosteal-derived cells.


The solution of hydroelastic oscillations problems of complex stiffened non-prismatic thin-shelled structures of a whole ship hull is examined Ine solution of the problem is achieved by a combination of module element method (to present the behaviour of the elastic structure) and boundary element method (to present the behaviour of adjacent fluid) The equations describe coupled oscillations of the system "structureliquid without preliminary determination of the added fluid mass The results of practical calculations are given.


RapidSmith is an open-source framework that allows for the exploration of novel approaches to the FPGA CAD flow for Xilinx devices. However, RapidSmith has poor support for manipulating designs below the slice level. In this paper, we highlight many of the projects RapidSmith enables and present extensions incorporated into "RapidSmith 2" that expose LUTs and flip-flops for direct manipulation in custom-built CAD tools. To demonstrate the utility of RapidSmith 2 we present the results of work to identify BELs in a design which must be clustered together and a tool that does pre-packing clustering accordingly.


As a first step towards the general global-in-time stability for the Boltzmann equation with soft potentials, in the present work, we prove the quantitative lower bounds for the equation under the following two assumptions, which stem from the available energy estimates, i.e. (ⅰ). the hydrodynamic quantities (local mass, local energy, and local entropy density) are bounded (from below or from above) uniformly in time, (ⅱ). the Sobolev regularity for the solution grows tempered with time.


As a form of government's commitment to achieving the Millennium Development Goals (MDGs), immunization activities is one of the priority activities of the Ministry of Health. Until now, Indonesia is still the fourth largest country in the world b


Objective:
 Heart failure (HF) is a major and growing public health problem worldwide. Recently our lab has identified HIPK2 as an essential kinase to maintain basal cardiac function. However, the role of cardiomyocytes specific HIPK2 (CM-HIPK2) in myocardial inflammation is unknown.

 Methods:
 α-MHC promoter-driven, Cre mice were crossed with HIPK2
 fl/fl
 mice to generate CM-HIPK2 KO. Echocardiography was performed to assess cardiac function. Immunoblotting assays were performed to determine the expression of HIPK2, CD39, CD73, and other signaling pathway . Flow cytometry and ELISA were performed to study the dynamics of inflammation.

 Results:
 Consistent with our previous report
 ,
 echocardiography confirmed an impaired cardiac function in 3 months old CM-HIPK2 KO as compared to their littermate controls. Importantly, cardiac function in the KOs starts to deteriorate at ~2.5 months of age, thus, at two months of age, the cardiac function of KO and littermate control was comparable. Comprehensive immune profiling of CM-HIPK2 KO and littermate control hearts were performed at two months of age. We observed an increased frequency of infiltrated CD45
 +
 leukocytes, CCR2
 +
 pro-inflammatory macrophages, Th17
 +
 , Th9
 +
 , CD45
 +
 TNFα
 +
 , CD45
 +
 IL1β
 +
 , CD45
 +
 Ki67
 +
 cells but diminished frequency of Myeloid-derived suppressor cells (MDSCs), TCRαβ
 +
 CTLA-4
 +
 and TCRαβ
 +
 PD-1
 +
 in the CM-HIPK2 KO hearts. Mechanistically, we observed a significantly reduced expression of CD39 and CD73 over HIPK2 deleted cardiomyocytes. Indeed, CD39 and CD73 are the key players of purinergic signaling regulated inflammation response.
 In-vitro
 studies with neonatal rat ventricular cardiomyocytes (NRVMs) corroborated the
 in-vivo
 findings. Specifically, adenovirus-mediated overexpression of HIPK2 significantly increased CD39 expression. Consistently, Ad-shRNA-HIPK2 expression suppressed the CD39 expression. Taken together, our findings suggest a critical role of CM-HIPK2 in purinergic signaling mediated myocardial inflammation.

 Conclusions:
 CM-HIPK2 maintains basal cardiac function by controlling purinergic signaling regulated myocardial inflammation. Future work will explore the underlying mechanism of HIPK2 mediated regulation of CD39 and CD73.


Design rules and the problem of design rule checking are introduced. The critical problem of design rule checking is the execution time required to check a complete chip. Proposed solutions try to take advantage of hierarchical aspects of a layout. The algorithm presented in this paper proposes a different approach. Observing that design rule checking is a very local operation, a method is described for partitioning a design for checking on a multiprocessor. An implementation is described and results are given for runs on a single processor. These results indicate that speedup proportional to the number of processors is possible.


Vertically unstable and complex bilateral sacral fractures are a result of high-energy mechanisms that are often associated with other injuries1-19. Vertically unstable sacral fractures result in the separation of the hemipelvis from the lumbar spine, whereas complex bilateral fractures result in a complete dissociation of the appendicular and axial skeleton. Recently, the surgical treatment algorithm for these fractures has changed, with an increasing number of surgeons advocating for the use of spinopelvic fixation or triangular osteosynthesis, a combination of spinopelvic fixation along with sacroiliac or transsacral screw fixation, to increase the stability of the construct and to allow for early weight-bearing with decreased concern for secondary displacement1-19.

### Osseous and Ligamentous Anatomy

The sacrum is a rhomboid-shaped bone consisting of five fused segments that is the lowest functional section of the spinal column and acts as the keystone of the pelvic ring20. When force enters the sacrum, it propagates laterally across the sacroiliac joints into the pelvis. Because of the shape of the sacrum and the orientation of the sacroiliac joints, axial forces stabilize the sacroiliac articulation in the pelvic outlet plane; however, in the pelvic inlet plane, the osseous configuration lacks inherent stability. The interosseous ligaments and posterior sacroiliac ligaments provide the majority of the intrinsic stability. Comparatively, the sacrospinous and sacrotuberous ligaments provide the extrinsic stability21.

The osseous architecture of the sacrum can be …


Background. Linguo-cultural approach to the description of new metaphorically motivated meanings that are emerging in the modern Russian language allows to reveal to foreign students the implicit aspect of the semantics of Russian vocabulary. Relevancy of the linguo-cultural approach to the description of new metaphorically motivated meanings in educational purposes is based on the fact that the majority of new word meanings is characterized by national and cultural specifics and therefore comprises an implicit, «encoded» aspect of the Russian word semantics for foreign students of philology. The article offers different explication ways of national and cultural connotations which underlie the figurative meanings relevant for native speakers. Materials and methods. Analysis and comparison of materials from lexicographical sources; component analysis of vocabular meanings; analysis of associative and verbal fields; free association experiment; Russia National Corpus data analysis with the approach of contextual use of vocabulary. Results. Many semantic neologisms that have emerged at the turn of XXI century contain in their meanings connotations and assessments that reflect the axiological hierarchy of Russian linguoculture however have not been expressed in the dictionary definition of a word. This is why these connotations and assessments need to be revealed in the educational dictionaries oriented at foreign students. Conclusions. It is the linguocultural approach aimed at discovering the reason of the national and cultural connotation emergence (that are «encoded» for foreign students) which allows to develop ways of revealing the content of new metaphorically motivated meanings in educational purposes.


With present domestic the pipeline has constructed to compare,the alloy steel used is the highest Level(API-5L)X80 Pipeline,with the largest diameter(1 219 mm),and the highest design pressure(12 MPa).How to ensure the welding quality is the key to this project.The author has done a lot of tests on the Second West-East gas X80 alloy steel pipeline using the metal powder core flux-cored wire welding,test results show that high-performance welding process optimization,the strict control welding process for welding of X80 alloy steel pipeline is feasible,it provides a method for the welding of high strength steel,too.


This paper examines hedge funds'relation to systemic risk, and how hedge funds with a high systemic risk contribution perform during the times of …nancial distress. I measure hedge funds' systemic risk contribution using an approach related to the Acharya, Pedersen, Philippon, and Richardson (2010) and Adrian and Brunnermeier (2009) approaches. The …ndings suggest that hedge funds'systemic risk contribution vary signi…cantly based on the fund characteristics that are associated with the fund capital structure. In addition, I …nd that the hedge funds having a high systemic risk contribution are not usually exposed to high idiosyncratic fund-level risk. Using multivariate regressions and portfolio sorts, I …nd that hedge funds with a high systemic risk contribution deliver signi…cantly lower risk-adjusted returns than their peers especially during the times of systemic episodes. Finally, …nancial and operational risks, but not systemic risk contribution, remain the main explanatory variables in predicting fund failures. JEL Classi…cations: G23, G28, C29. …


For any type of target tracking and navigation, the localization is critical for tracking/navigation missions. The real-time localization error correction for the atmospheric refraction can be achieved through the ray bending compensation by the refractivity profiles or ray-tracing. Ray-tracing can be computed through the real-time weather data (surface temperature, pressure, and relative humidity or dewpoint) from daily/hourly, local meteorology, or global climatology data. Operational results of this new technique Indicate that the time difference of arrival (TDOA) of radio-waves vary dynamically in hours, days, months, seasons and geographically. Errors for the low elevation angles less than 10 degrees are much higher than expected for higher frequencies above 300 MHz, and it should be calibrated or corrected in tactical operation and strategic system implementation. The localization of tracking and navigation mission can be achieved within a couple of hundred meters if the integrity of measured tactical data is well within the confidence boundary.


3970 feed samples were analysed for the fusariumtoxins deoxynivalenol and zearalenone. 979 (24.6%) of the submitted feed samples from farms with case history (swine herds: decreased feed intake and daily weight gain, vomiting, cannibalism, impaired fertility, small litter size, weakness of newborn piglets, prolonged oestrus of sows; cattle: persistence of follicular ovarian cysts, enteritis, decreased slaughter weight, feed refusal). 74% of the samples contained cereal and corn ingredients respectively or were complete diet samples from swine herds. Based on economic losses the fusariumtoxin deoxynivalenol is most important in Austrian husbandry and particularly found in maize, cornsilage, wheat and oat.


We describe a novel coincidence addressing plan for multiplexing multi-element liquid-crystal matrix displays which depend upon dynamic scattering (electrohydrodynamic turbulence) to achieve a light-scattering state. This plan exploits the qualitatively different responses of certain nematic liquid crystals to electrical signals of different frequencies. The approach was motivated by the absence of a sharp threshold in the scattering versus voltage characteristic, an attribute which has impeded the use of voltage half-select schemes.


This paper investigates the finite time fault-tolerant attitude control for rigid-flexible coupling satellites in large angle rapid maneuver when some of the actuators are in the fault condition. Based on the first-order approximate method, a more accurate dynamic model for rigid-flexible coupling satellites is set up. Then, Legendre polynomial-based neural network is introduced to estimate the lump perturbation including the estimation error of the fault control torque, high-order flexible coupling terms, external disturbances, and model uncertainties. With the estimation value as the compensation effort, a finite time fault-tolerant attitude controller is designed based on the nonsingular fast terminal sliding mode. And in order to guarantee that the output of the Legendre polynomial-based neural network stays inside the bound of the lump perturbation, a switch mechanism is introduced to generate a switching between the proposed fault-tolerant attitude controller and a robust controller. The proposed fault-tolerant attitude controller is shown to have the finite time stability, with fast convergence rate, high accuracy, disturbance rejection, chattering attenuation, flexible vibration damping through theoretical analysis and simulations, meanwhile the better representation capability of the Legendre polynomial-based neural network, whose basic functions are implemented using only the desired attitude, makes the controller design simple and efficient.


Fulfilling the recent needs of visualization of variable in time 3D objects in virtual reality environment requires development of new approach towards combining rapid 3D shape measurement with data filtering, coding and streaming. These operations have to enable performing real-time transmission and visualization of 3D data in virtual reality. In the paper the novel system based on digital structure light projection applied to gather 3D data representing variable in time objects and extended numerical procedures coupled with virtual camera concept for interactive object visualization is presented. The proposed measurement and data processing methodology has been verified successfully at computer generated models of moving and morphing 3D objects. Both types of data have been visualized with the average frequency of 10 frames per second in virtual reality environment.


Availability of water is one of the key factors influencing the location of various industries at a given site. However, the importance of water to different industries does vary ranging from being an ingredient in the output of the firm, to that needed for sanitational purposes. As demand for water increases, competition for its use also does. This study examines the present level of water use, particularly the industrial use of water in Saskatchewan. Total water use is estimated at 677.5 thousand cubic decameter, of which only 3.4 percent is for industrial and commercial purposes. The industrial water use is projected to increase by about 95 percent of its present level by the year 2000. Different industries had different levels of water need. Higher level of water use was estimated for slaughtering and meat processing, poultry processing, flour and breakfast cereal industry, and vegetable oil mills.


Elemental and isotopic abundances of Ar and Xe were measured in three grain-size separates in the dark phase of the enstatite achondrite Pesyanoe by stepwise heating, using a combination of pyrolysis and combustion steps. The data reveal a low-temperature gas fraction with Ar/Xe ratios close to the solar ratio and isotopically similar to solar-type Ar and Xe observed in lunar samples. The gas released at intermediate temperature steps shows that Ar and Xe are isotopically fractionated, compared to the low-temperature components. Pesyanoe does not have excess Ar-40 and fission Xe, which means its parent body was too small for ion reimplantation. It is concluded that solar-type Xe isotopic abundances can be inferred from the low-temperature component. A comparison of Pesyanoe and lunar data shows that isotopic signatures of solar-wind Xe, as sampled at two different points in solar system space and time, are identical within experimental error.


The information to InClude m a summary vanes depending on the author's mtentmn and the use of the summary To create the best summaries, the appropriate goals of the extracting process should be set and a guide should be outlined that instructs the system how to meet the tasks The approach described m thin report m intended to be a basic archltecture to extract a set of concme sentences that are indicated or predlcted by goals and contexts To evaluate a sentence, the sentence selection algorithm simply measures the mformatlveness of each sentence by comparing with the determined goals, and the algorlthm extracts a set of the hlghest scored bentences by repeat apphcatmn of thin com-


JEADV 2006, 20, 999–1032 © 2006 European Academy of Dermatology and Venereology 1011 In 1957, Ronchese and Kern reported a 'lymphangiomalike' variant of KS; since then, some other authors have reported it as 'bullous KS'. Davis et al. stated that the word 'bullous' is only an inaccurate clinical description that is best not used. Cossu et al. stated that a 'bullous' clinical appearance may be indicative of a specific histological presentation. We agree with these observations and therefore named it as lymphangioma-like KS. Kaposi's sarcoma can present as many types of primary lesions. However, bulla-like lesions of KS have been only infrequently reported in the literature (21 cases). The histological findings of the lymphangioma-like variant have been described as the presence of vascular channels lined by banal-appearing endothelia permeating the dermis in the absence of a spindle cell proliferation. These vascular channels are dilated and bizarrely shaped and are located in the upper portion of the dermis. Clinically, lymphangioma-like KS can present as a typical-appearing KS but also has a unique clinical appearance termed bullalike. However, a bulla-like clinical appearance may be indicative of this histological pattern. The most common clinical presentation is a bulla-like lesion (12 out of 25 cases). The formation of bulla-like lesions in the lymphangioma-like variant is poorly understood. Chronic lymphoedema and unique lower extremity haemodynamics have been implicated. Two of our reported patients presented oedema associated with KS lesions. Likewise, the lower extremities are the predilected site of presentation of this KS variant (21 out of 25 cases). One of our patients presented rapid deterioration associated with the presentation of bulla-like lesions. It has been reported that lymphangioma-like KS can result in a fatal outcome. All the remaining cases showed a slowly progressive course. Davis et al. reported that the location of the lymphangiomalike spaces and their predilection for sites of extensive papillary dermal fibrosis suggest a relationship between electron beam therapy and lymphangioma-like KS in their patient, as in the last patient described in this report. In conclusion, lymphangioma-like KS can present as a typicalappearing KS but a bulla-like lesion may be indicative of this histological pattern. The lower extremities are involved in the majority of cases and oedema can also be seen.


Burr (Burr) removal device in accordance with the present invention, to form a certain height, the upper surface is a flat table, formed on the upper surface of the table, and a jig for fixing the workpiece, is provided at the top of the table, according to the table long side the mobile frame so as to be movable along the guide rail movably arranged movable frame and, is provided respectively on the table top on both sides or both sides of which, is provided in the guide rail for guiding the moving frame, one side of the movable frame, a movement motor for generating a power, and for rotation by a motor provided on the moving frame inner side, for rotation by a motor in the first polishing unit for deburring the upper end surface of the work piece at the top of the table, the moving frame inside it is provided, the second polishing unit, said mobile frame for polishing work on the top surface of the workpiece at the top of the table Side the top and, is provided between the first polishing unit and the second polishing section top, is formed at a side of the first polishing unit and the second buffer unit, and the mobile to dampen vibration generated by the polishing part frame, wherein It relates to a jig, motor movement, the first polishing section, the member being configured to include a control box for controlling a second operating grinding portion (burr) removal device.


Abstract Background: Despite several empirical studies that have emphasized the problematic and ineffective way in which health organizations 'correct' information which does not come from them, they have not yet found ways to properly address vaccine hesitancy. Objectives: (1) Examining the responses of groups with different attitudes/ behaviors regarding vaccination; (2) Examining the effect of the common methods of correcting information regarding the response of subgroups, while examining issues of reliability, satisfaction, and information seeking, as well as how health organization tools aid the decision-making process regarding vaccines. Methods: A simulation study that included 150 parents of kindergarten children was carried out. Results: Significant difference was found among the various groups (with respect to vaccination behavior) regarding the extent of their trust in the Ministry of Health (χ2(3) = 46.33; P < 0.0001), the reliability of the Ministry of Health's response (χ2(3) = 31.56; P < 0.0001), satisfaction with the Ministry of Health's response (χ2(3) = 25.25; P < 0.0001), and the level of help they felt the Ministry of Health's tools provided them regarding vaccine-related decision making (χ2(3) = 27.76; P < 0.0001). Conclusion: It is important for health organizations to gain the public's trust, especially that of pro-vaccination groups with hesitant attitudes, while addressing the public's fears and concerns.


Since 1950s,classical modernization theory as the generalization of the process of Europe society modernization has been affected by Social Darwinism obviously.Two defects of the Social Darwinism have determined that classical modernization theory's explanation is weak and room for the explanation is small.After 20th century,non-western countries are engaged in the modernization practice.As perspective is single,analysis method is limited,analysis conclusions are absolute,analysis model is dual,Classical modernization theory encounters the explained plight unprecedented.Today,further reflection on the explanation plight of classical modernization theory will deepen the understanding of modernization,and give new times information to modernization theory.


Probably the first concrete evidence of presynaptic receptors was published in a classical paper by Masland and Wigton in 1940.' The authors reasoned that the fasciculation, rather than fibrillation, that follows the intraarterial injection of acetylcholine (ACh) or an anticholinesterase (anti-ChE) agent (physostigmine, neostigmine) into a skeletal muscle must reflect the synchronous firing of entire motor units rather than activation of individual muscle fibers. In support of this concept they quoted a much earlier study by Langley and Kato in 1915, in which it had been shown that injection of physostigmine does not produce fasciculation in chronically denervated muscle.2 Richard Masland (a University of Pennsylvania neurologist, who subsequently became director of the then National Institute of Neurological Diseases) and Wigton monitored both muscle action potentials and antidromic firing along the corresponding motor nerve; following the injection of ACh or an anti-ChE agent, they recorded synchronous bursts of activity a t both. Furthermore, both were blocked by curare. Therefore, they concluded that cholinergic nicotinic receptors are present in both presynaptic motor nerve terminals and the postsynaptic portion of the motor end plate. A number of confirming reports followed. Abdon and Bjarke concluded that tubocurarine exerts its blocking effect predominantly at the presynaptic motor terminal, probably by interfering with the release of ACh.' Walter Riker and associates examined a number of analogues of neostigmine, with and without anti-ChE activity, and arrived at similar conclusions.4~s The first suggestion of presynaptic receptors in autonomic ganglia was published in I950 by Laporte and Lorent6 de No, who showed that transmission in a turtle ganglion was blocked by tubocurarine a t a predominantly presynaptic site.' Unlike what occurs a t motor end plates of skeletal muscle, ACh and anti-ChE agents fail to induce retrograde preganglionic firing when injected into normal mammalian sympathetic ganglia.' This is probably due to the difference i n the geometry of the two presynaptic sites: whereas motor nerves terminate in sizable structures a t the motor end plate, the overwhelmingly axodendritic synapses of preganglionic terminals are extremely small twigs.' However, following infection with pseudorabies virus, such an action is apparcntly unmasked in ganglia. In the late 1950s John Dempsher and associates showed that when pseudorabies virus is introduced into the eyc of an anesthetized cat, it passes via the postganglionic sympathetic fibers to the superior cervical ganglion (SCG).9-" After a few days' latency, spontaneous, continuous bursts of firing develop synchronously in the postganglionic (anterograde) and preganglionic (retrograde) trunks. Simultaneously, show waves of localized depolarization, probably representing generator potentials, were detected at both poles of the ganglion. All this activity was suppressed by tubocurarine, suggesting that it was due to the action of ACh at both preand postsynaptic receptors.


This paper studied the promotion of whey protein hydrolysate (WPH) by Neutrase for yogurt fer- mentation and its effect on the sensory quality and water holding capacity of yogurt. The results showed that, WPH obviously promoted the fermentation of yogurt, resulting in a shorter fermentation time. Within the concentration of 6%(w/w), the more the hydrolysate, the faster the fermentation speed. Moreoer, WPH with this rang of concentation can maintein the natural sensory of yogurt. Hydrolysate with the concentration 2% lowered the water holding capacity (WHC) of yogurt,and with the increasing of WPH, WHC decreased. WPH with the concentration of 6% can significantly promote the growth of Streptococuus thermophilus in yougurt (P0.05), thus can reduce half of the amount of inoculation in the industry production of yogurt.


One embodiment of the present invention, with respect to a call receiving method of a UE in a wireless communication system, a call receiving method of a UE comprises the steps of: establishing a one-to-one connection with a relay UE; transmitting an SIP register message including information pertaining to an IMS registration cancellation of the relay UE to an SIP server; and receiving a call from the SIP server, wherein when a connection between the UE and the relay UE is cancelled, the relay UE is IMS registered.


A variety of restrictions was put forward,which can influence the result of object-selection of LAMOST.An object-selection model was established based on static restrictions.The effects of each restriction were analyzed by means of simulation.


We obtain positronium Hyperfine Splitting owing to the non-commutativity of space and show that, in the leading order, it is proportional to $\theta \alpha^6$ where, $\theta$ is the parameter of non-commutativity. It is also shown that spatial non-commutativity splits the spacing between $n=2$ triplet excited levels $E(2^3S_1)\to E(2^3P_2)$ which provides an experimental test on the non-commutativity of space.


Introduction: The incidence of Non-Hodgkin Lymphoma (NHL) is increasing, especially in people over 60 years of age. This population usually has a worse prognosis, probably due to comorbidities, functional deterioration and decreased tolerance to treatment. Therefore, a pre-therapeutic evaluation would be important to make decisions. The Comprehensive Geriatric Assessment (CGA) is the recommended tool for this evaluation, but it is a complex process that demands time and resources. We performed a study to evaluate the characteristics of the CGA in patients >64 years of age with NHL and to determine which domains can constitute a simplified model.
 Methods: This is a cross-sectional study with retrospective data collection of geriatric evaluations performed in >64 years with aggressive NHL (90% DLBCL, 10% PTCL) admitted to our institution between September 2015 and August 2017. Number of drugs, prescriptions in older adults was evaluated (STOPP), Lawton scale, Barthel scale, KATZ index, walking speed, Up and Go time (TUG), Mini-mental test, Yesavage scale, Gijón scale, Mini-nutritional, Geriatric syndromes (Incontinence, Falls, Pressure ulcers, Immobility, Sensory Deficits, Osteoporosis), and Accumulated Disease Scale in Geriatrics (CIRS-G). The CGA included 9 domains, and fragility was defined as deterioration in >2 domains. The different evaluations were compared with fragility. Multivariate models were constructed using logistic regression.
 Results: We included 253 patients with an average age of 76 years. 62% had >1 affected domain, and 40% were considered fragile (>2 affected domains). In the bivariate analysis, age >85 years, and all the geriatric scales except STOPP, were strongly associated with fragility. The final model had 6 variables: Use of >5 drugs ( OR 773.1, 95% CI,4.5-132134.4;p=0.011), Lawton scale <7 (OR 385.2,95%CI, 20.1-7363.5;p<0.001), TUG >20 (OR 124.6,95%CI, 6.2-2489.8;p=0.002), Mini-mental <23 (OR 53.5,95%CI, 3.7-778.8;p=0.004),Yesavage scale >5 (OR 118.7,95%CI, 11.2-1254.5;p<0.001), and presence of at least one geriatric syndrome (OR 235.6,95%CI, 13.3-4158.7;p<0.001). Removing the Mini-mental minimally affected the model, but suppressing two or more variables does weaken the model.
 Conclusions: In our cohort of patients older than 64 years with aggressive NHL, a model based on five measurements (i.e. number of drugs, TUG, Lawton scale, Yesavage scale and Geriatric Syndromes) could constitute an evaluation with an efficiency similar to a complete CGA.

 Castillo: Pharmacyclics: Consultancy, Research Funding; Genentech: Consultancy; Millennium: Research Funding; Abbvie: Consultancy, Research Funding; Janssen: Consultancy, Research Funding; Beigene: Consultancy, Research Funding.


Computed tomography (CT) streak artifacts caused by metal implants have long been recognized as a problem that limits various applications of CT imaging. An effective and robust algorithm is highly desirable to minimize metal artifacts and achieve clinically acceptable CT images. In this work, the raw projection data is viewed as "incomplete" in the presence of metal shadows. Shape and location of metal objects are automatically identified and used as prior knowledge for accurate segmentation of metal shadows in projection domain. An iterative algorithm based on constrained optimization is then used for the image reconstruction. This algorithm minimizes a quadratic penalized smoothness measure function of the image, subject to the constraint that the estimated projection data is within a specified tolerance of the available metal-shadow-excluded projection data, with image non-negativity enforced. The constrained minimization problem is optimized through the combination of projection onto convex sets (POCS) and steepest gradient descent of the smoothness measure objective. Digital phantom study shows that the proposed constrained optimization algorithm has superior performance in reducing metal artifacts, suppressing noise and improving soft-tissue visibility. Some comparisons are performed with the filtered-back-projection (FBP), FDK, POCS and constrained optimization with total-variation (TV) objective. Although the algorithm is presented in the context of metal artifacts, it can be generated to image reconstruction from incomplete projections caused by limited angular range or low angular sampling rate in both 2D and 3D cases.


Carbon fiber composites, particularly those with polymer matrix, have become the dominant advanced composite materials for aerospace, automobile, sporting goods, and other applications due to their high tensile strength, high modulus, low density, higher strength to weight ratio and reasonable cost This paper presents the development of mathematical model to predict mechanical properties of nano copper oxide (CuO) filled carbon fiber reinforced plastics (CFRP). In this work composites are fabricated from PAN based unidirectional carbon fiber and different wt % of nano CuO particles dispersed in Araldite LY556 Epoxy resin through compression molding technique. As per ASTM standards tensile and compression test are carried out in Universal Testing Machine. Microstructure of samples has been investigated by scanning electron microscope (SEM). Hence the dispersion of reinforcement was noted. The results indicated that increase in weight % of nano CuO particles improves the the mechanical properties.


The presence of distinctive internal membrane compartments, dynamically connected via selective transport pathways, is a hallmark of eukaryotic cells. Many of the proteins required for formation and maintenance of these compartments share an evolutionary history. We have recently identified a new conserved protein complex – the SEA complex – that possesses proteins with structural characteristics similar to the membrane coating complexes such as the nuclear pore complex (NPC), the COPII vesicle coating complex and HOPS/CORVET tethering complexes. The SEA complex in yeast is dynamically associated to the vacuole. The data on the function of the SEA complex remain extremely limited. Here we will discuss a possible role of the SEA complex based on the data from genetic assays and a number of functional studies in both yeast and other eukaryotes.


Ajmaline decreased the upstroke velocity of action potential
and its amplitude, very likely by inhibition of sodium current
INa. The observed prolongation of action potential was probably
related to the inhibition of transient outward potassium
current Ito, the main repolarizing current in rat. This effect
predominates over the opposite effect of the inhibition of
calcium current ICaL, partly because of lower IC50.


This work was carried out to study the effect of photoperiod on Trichogramma cordubensis Vargas & Cabello biology. T. cordubensis was reared on Ephesiia kuehniella Zeller eggs at 20°C and 75±5% of HR. The essay compnsed diiferent photophase (L): scotophase (D) combinations that simulated the day length of summer (16:8), winter (8:16) and spring or autumn (12:12) seasons in the Azores. Photoperiod did not influence the parasitoid longevity, emergence rate and parasitism. However, it had a significant effect on the parasitoid egg to adult developmental time, the last enJarging with increasing photophase.


Suaeda fruticosa (L.) Forssk plants grown in saline conditions (200 to 400 mol m !3 NaCl) had greater fresh and dry weights than those grown in non-saline controls, and 600 to 1000 mol m !3 NaCl inhibited growth. Gibberellic acid and kinetin both alleviated some of the inhibitory effects of salinity at 800 mol m !3 NaCl on shoot growth of S. fruticosa while root growth was promoted by kinetin. Tissue water content increased in up to 200 mol m !3 NaCl but decreased with a further increase in salinity. Water potential and osmotic potential of plants became more negative with an increase in salinity. Leaf Ca 2 ' ,M g 2 ', and K' concentration decreased with increasing salinity, while both Na' and Cl ! increased and reached 1391 and 1673 mmol kg !1 dry weight, respectively. Total glycinebetaine content of shoots was highest at 600 to 1000 mol m !3 NaCl. ( 2000 Academic Press


The operating environment of cellular networks can be in a constant state of change. One Singaporean operator expressed difficulty with the coverage assertion (CA) problem of whether regulated minimum coverage is met, especially in urban areas. Currently, the operator manually appraises coverage through laborious and expensive walk/drive-tests. In this paper, we propose Tattle, a distributed, low-cost and comprehensive cellular network measurement collection and processing framework. We exemplify Tattle by leveraging on participating UEs to report on network coverage in real-time. Tattle exploits wireless local-area interfaces to exchange RSCP measurements amongst devices to preserve the co-locality of readings and conserve power. We propose U-CURE, a clustering algorithm which considers sample location uncertainty and the knowledge of device co-location to remove erroneously localized readings. We develop a prototype app on the Android™ platform as a proof-of-concept of the Tattle framework. We then use the Tattle framework to perform extensive RSCP measurement collection and processing in various areas in Singapore, collecting over 3.78 million readings. We present visualizations of mean signal coverage and RSCP CDFs for various areas of interest. The latter is a key output of Tattle, which helps operators to appraise coverage and solve the CA problem by relying on subscriber measurements, instead of expensive, laborious and limited-scale walk-/drive-tests.


The Australian heath plant, B. ornata (Proteaceae), has been grown in water culture at a low phosphate level (0·001 p.p.m. phosphorus). Such plants, 22 weeks or more in age, have been used for 24-hr uptake experiments with 3l1P-labelled orthophosphate. Characteristics of 32p distribution are a low translocation from roots to tops, and the formation of a large fraction of trichloroacetic acid-insoluble phosphorus in the roots.


This article explores a counterintuitive intersection of class, gender, and race within two politically antagonistic white movements—white nationalists and white antiracists. Ethnographic field-notes, in-depth interviews, and content analysis provide comprehensive data and triangulation for how implicit perceptions of class and gender are intertwined with the social construction of an ideal white, male, middle-class identity. While both organizations express antithetical political goals, they together reinforce broader discourses about whiteness and white supremacy. In so doing, these two organizations present an empirical and theoretical puzzle: How and why do two supposedly antithetical and divergent white male organizations simultaneously rationalize the inclusion and exclusion of women and the lower class from their ranks? Findings gesture toward tempering conceptual models of white male identity formation to further explore how cultural schemas are utilized toward the construction of both identity formation and interest protection.


It is shown that the feasibly constructive arithmetic theory IPV does not prove (double negation of) LMIN(NP), unless the polynomial hierarchy CPV‐provably collapses. It is proved that PV plus (double negation of) LMIN(NP) intuitionistically proves PIND(coNP). It is observed that PV + PIND(NP ∪ coNP) does not intuitionistically prove NPB, a scheme which states that the extended Frege systems are not polynomially bounded. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


Our home is becoming more and more intelligentized. In the home network, the residential gateway plays a key role in the data interchange between external networks and home network, this paper proposes an idea that the home network should guarantee a unique visiting interface. Furthermore, this paper designs and implements the central forwarding mechanism of the residential gateway, and exchanges between outer networks and home network must be through the residential gateway. This paper is of valuable reference for network researchers and engineers to be engaged in the further study on the home network.


issue. If such arbitrary and vindictive punishment was possible then, it is possible now. As a historian who has crossed swords with Andrew Moore in the past, it is pleasant to be able to commend this book. With a few unimportant exceptions, such as gratuitously describing a conservative politician as 'widely regarded as a closet Nazi by left-wing Australians' (174), this is a well-written, nuanced and fair-minded history. Taking the reader into the heart of a near-forgotten controversy, Moore has made a significant contribution to our understanding of the history of politics and free speech in Australia.


The transpiration cooling method was considered for a scram-jet engine to accommodate thermally the situation where a very high heat flux (200 Btu/sq. ft sec) from hydrogen fuel combustion process is imposed to the engine walls. In a scram-jet engine, a small portion of hydrogen fuel passes through the porous walls of the engine combustor to cool the engine walls and at the same time the rest passes along combustion chamber walls and is preheated. Such a regenerative system promises simultaneously cooling of engine combustor and preheating the cryogenic fuel. In the experiment, an optical heating method was used to provide a heat flux of 200 Btu/sq. ft sec to the cylindrical surface of a porous stainless steel specimen which carried helium gas. The cooling efficiencies by transpiration were studied for specimens with various porosity. The experiments of various test specimens under high heat flux have revealed a phenomenon that chokes the medium flow when passing through a porous structure. This research includes the analysis of the system and a scaling conversion study that interprets the results from helium into the case when hydrogen medium is used.


Background: The distribution of house dust mite allergen (Der p1) in living rooms with smooth floor coverings, as measured in the middle compared with the border of the floor was investigated. It was hypothesized that activity causes displacement of Der p1, from the middle towards the border.


Abstract : Vehicles traveling through an atmosphere at hypersonic speeds generate strong shock waves. These shock waves generate extremely high gas temperatures within the shock layer between the shock itself and the surface of the vehicle. As the gas reaches such high temperatures, its vibrational degrees of freedom become excited and diatomic and polyatomic molecules dissociate into reactive atomic species. At high altitudes characteristic of hypersonic flight where the free-stream density is low, these reactive species diffuse through the boundary layer and may chemically react with the vehicle s thermal protection system (TPS). Many TPS materials act as a catalyst for the heterogeneous recombination of dissociated species back into molecules. Such exothermic surface reactions transfer additional energy to the vehicle surface and thus contribute to the heat flux and overall heat load that the TPS must withstand. For example, studies have shown that surface catalysis can contribute up to 30% of the total heat load for Earth reentry [1].


Palindromic rheumatism was first described by Hench and Rosenberg in 1941, and three years later a detailed account of their 34 cases appeared in the Archives of Internal Medicine (Hench and Rosenberg, 1944). A number of individual case reports subsequently appeared in the literature (Ameen, 1954; Cain, 1944; Ferry, 1943; Ginsburg, 1948; Grego and Harkins, 1944; Gryboski, 1948; Hopkins and Richmond, 1947; Lewitus, 1954; Mazer, 1942; Neligan, 1946; Paul and Logan, 1944; Paul and Carr, 1945; Perl, 1947; Rotes Querol, 1956; Salomon, 1946; Scheinberg, 1947; Thompson, 1942; Parkes Weber, 1946; Wingfield, 1945; Wirtschafter, Williams, and Gaulden, 1955; Wolfson and Alter, 1948; Wassmann, 1950; Zentner, 1953). However, there have been few reports of series of patients with this syndrome (Ansell and Bywaters, 1959; Dames and Zuckner, 1961; Rotes Querol and Lience, 1959) and although reference is made to 140 cases seen at the Mayo Clinic (Ward and Okihiro, 1959) these have not yet been reported in the literature (Ward, 1965). Hench and Rosenberg (1941) coined the term "palindromic rheumatism" to describe recurring attacks ofjoint pain and swelling. Usually only one joint was affected at a time, although practically every joint in the body had been affected, including the temporo-mandibular joint. The shoulder, knee, wrist, and small joints of the hand were most frequently involved and pain in the neck was common. The onset was often sudden and although an attack could start at any time of the day or night it frequently began in the late afternoon. Each attack lasted a few hours or a few days, but rarely as long as a week. Pain was most severe a few hours after onset and often prevented sleep; it could be very disabling and even lead to admission to hospital. Joint swelling was usually evident and the overlying skin was often red. The interval between attacks was very variable and irregular, unlike that in intermittent hydrarthrosis, and between attacks the joints appeared normal. One third of their patients experienced so-called "para-articular attacks" affecting the soft tissues near joints or even overlying muscles away from joints. Painful non-pitting tender swellings an inch or more in diameter, and occasionally much larger, appeared over the forearms, back of wrist, or heel. Sometimes the finger tips became swollen and transient intra-cutaneous or subcutaneous nodules were observed on the hands, but usually disappeared within a few days. Patients suffering from palindromic rheumatism remained well and did not lose weight. Attacks were usually afebrile. Radiographs were normal in most cases or showed coincidental degenerative changes. Laboratory investigations usually gave normal results, although there was sometimes a transient rise in the erythrocyte sedimentation rate during an attack, the white cell count might show a relative lymphocytosis, and the serum fatty acids were increased in some patients. In a few cases, biopsy of a joint during an attack revealed a non-specific acute inflammation which subsided rapidly; the fibrinopurulent joint fluid contained many polymorphs but was sterile on culture and contained no urates. Most patients experienced a succession of attacks affecting different joints at irregular intervals; they might occur a few times a year or many times a week, and might continue indefinitely over 20 years or subside spontaneously. No treatment was of value. Hench and Rosenberg (1944) concluded that "despite thousands of attacks suffered during a grand total of 307 years of illness, not a single joint had been crippled permanently". The characteristics of palindromic rheumatism as described by Hench and Rosenberg (1944) may be summarized as follows:


Abstract The paper is devoted to development of tracking control system for plasma shape and current of tokamak-reactor as a future practically inexhaustible source of energy production. The aim of the plasma magnetic control system is to track scenario currents in poloidal field coils, some magnetic surface or separatrix and plasma current during phase of plasma current ramp-up. This aim is achieved by cascade control scheme which consists of multivariable loop of tracking system for scenario currents and the second loop for plasma current and shape control. Two basic approaches are used for cascade control: decoupling and robust H ∞ loop shaping design. In doing so, the scalar proportional and robust controllers are applied to stabilize plasma vertical speed around zero of unstable vertical plasma position. The simulation results of closed loop systems obtained on linearized models of nonlinear plasma-physics DINA code are presented.


Facebook has revolutionized the world in which we communicate. In just a few mouse clicks, you can access personal information, pictures, recent conversations, and much more about your Facebook "friends." With these things in mind, it is important to carefully consider the implications of becoming a Facebook friend. This 4-page fact sheet discusses professionalism and legal considerations for using Facebook as a tool to promote Extension programs. Written by Amy Harder, Hannah S. Carter, and Christy Chiarelli and published by the UF Department of Agricultural Education and Communication, April 2011.


As mentioned in the previous chapter, series of primary statistical analysis, followed by an estimation of measurement models, which is required prior to estimating the proposed structural model were evaluated. The requirements of the unidimensionality, reliability and validity were satisfied by the measurement model and hence, the hypothesized relationships among the constructs can be studied further. This chapter is organized into three phases. In the first phase, a second-order factor model of TQM was tested. The second-order factor model of TQM as a latent factor, consisted of nine first order-factors such as continuous improvement, process management, customer focus, empowerment, feedback, teamwork, relation, involvement, and top management support. The second phase of the study in this chapter, hypothesis direct relationship between the TQM, job satisfaction and school performance factors and lastly,


In this work, solar radiation availability has been estimated for south‐facing inclined surfaces in India. Five different climatic zones prescribed by Energy Conservation Building Code (ECBC) for India have been considered. A comparison of optimum tilt angles and corresponding incident solar radiation for representative locations under different climatic zones, that is, Srinagar (cold), Delhi (composite), Jodhpur (hot and dry), Mumbai (warm and humid), and Bangalore (Temperate) has been established. Gains in the availability of incident solar radiation in comparison with a horizontal surface observed for Jodhpur and Bangalore were found to be maximum (15.77%) and minimum (7.57%), respectively, on monthly optimum tilt angle. A loss of 5.74% for cold climate, 7.49% for composite climate, 6.16% for hot and dry climate, 4.30% for warm and humid climate, and 4.39% for temperate climate were estimated with surface tilted at annual optimum tilt in comparison with a surface at monthly optimum tilt angle. A linear relationship was observed between annual optimum tilt angles and locations latitude as βopt(annual) = 0.671 ϕ + 9.087 with R2 = 0.9984. It was concluded that climatic conditions can considerably affect the availability of incident solar radiation under different climatic zones. ' 2018 American Institute of Chemical Engineers Environ Prog, 38:e13050, 2019


The ongoing Quaternary period is marked by several glacial and interglacial cycles. These long and short-term variations are well preserved in the proxy record. Long-term proxy climate records provide a perfect setup to understand the response of earth towards these long and short-term variations in climate.


Sprinkler is a key component for farms and gardens. However, conventional sprinkler systems have limitations: underwatering and overwatering under evolving weather, not considering plant conditions, and burden of manual scheduling. We developed Autonomous Sprinkler System to remedy the limitations. We acquire environmental contexts with loT sensors, cameras, and actuators, and apply MAPE-K for autonomic control. We implemented the Knowledge with a SVM classifier for inferring the situations and a Fast R-CNN model for determining plant condition. Our experiments show the system yields a considerable savings of water consumption and promotes the plant health, all without human users' interventions.


Carcinoid tumours have the ability to secrete various peptides and bioamines that lead to carcinoid syndrome manifested as cutaneous flushing, diarrhoea, bronchial constriction and cardiac involvement. The deficiencies of vitamins D and B12 have previously been reported in patients with carcinoid tumours presumably due to chronic diarrhoea associated with the carcinoid syndrome. Herein, we chronicle the case of a patient with opioid use disorder who presented with small bowel obstruction that was found to be caused by a midgut carcinoid tumour. Laboratory studies revealed deficiencies of vitamins D and B12 even though he denied diarrhoea and had no other aetiology of deficiencies of these vitamins. Additionally, this paper presents a review of the published medical literature pertaining to clinical features, diagnostic investigations and treatment of intestinal carcinoid tumours and explores possible explanations for the observed deficiencies in these patients.


The Maocun underground karst river system in the peak cluster depression is an important source of groundwater in southwest China. Multitracers and high resolution water‐level‐monitoring technology were used to assess and evaluate the hydrogeological structure and flow dynamics. The results showed that the spatial geological structures of the sites had high heterogeneity. Scatter plots of environmental tracers divided the sampling points into groups under different water flow patterns. The karstification was found to increase from sites XLB and LLS to sites BY, SGY and BDP to sites CY and DYQ, where the main water flow patterns at these site groups were diffuse water, both diffuse water and conduit water, and conduit water, respectively. The response times of the subsystems were found to be influenced by the spatial structure, the degree of karstification, and the volume of precipitation and frequency. The average response times of SGY, BDP, ZK, and Outlet in the selected precipitation scenarios were 5.17, 4.08, 16.42, and 5.83 h, respectively. In addition, the EC, δ13CDIC, 222Rn, and δ18O exhibited both linear or exponential relationships. Overall, three hydrogeological conceptual models were constructed showing: (1) high precipitation driving the deep water, resulting in a concentrated flow regime and regional groundwater flow field; (2) both concentrated and diffuse water flows existing under moderate precipitation, resulting in mixed water flow field; (3) the water cycle in the shallow karst aquifer system under low precipitation causing the local groundwater flow field to be dominated by diffuse water flow.


In today's "呆" reading dāi,"待" reading "dāi" and "dai".Dāi sound in "stay" the meaning of the word there is the case mix."待" than the word "呆" there early,there is the word "待" in the pre-Qin,and "呆" was the classical Chinese of the "保",to the Yuan Dynasty is a "silly" significance.Before the Ming and Qing Dynasties,"待" had not the meaning of the word "stay" meaning,the meaning has begun since the Ming and Qing Dynasties.In the Ming and Qing Dynasties,"呆" only had the meaning of "stupid",but before and after the liberation in the contemporary literature it had the meaning of "stay",also at this time,"呆" "待" could be mixed."待" was read "dāi" after the mix by the impact of "呆".


Through analyzing reasons for the corrosion of cyclone separator for oxychlorination reactors,the material selection scheme and the installation improvement measures for cyclone separator were put forward.


As further plans develop, they will be posted on the SIGAPL web page; bookmark "www.aem.org/sigapl". • T HE NY/SIGAPL GRouP presented their 10th annum APL conference which they entitled APL as a Tool of Tkought, on January 31, 1998. This year, the conference was held at Stevens Institute of Technology in Hoboken, New Jersey. The conference chairman was Phil Benkard, and the program chairman was David Siegel David arranged the program so that several of the presentations were repeated, since the day consisted of five tracks.


Acquisition is the form of takeover of company's ownership by the acquirer so it results in the change of control on the company which has been taken over. This research is conducted in order to study the impact on the acquisition to the company's financial performance of Bank Rakyat Indonesia, Tbk. Using paired sample t test to find out whether there are differences in financial performance before and after or not. The assesment of financial performance is carried out by using financial ratio. Current Ratio undergoes enchancement. Debt to Equity undergoes declination while Debt to Total Asset ratio undergoes enchancement. Net Profit Margin and Return on Assets undergoes enchancement while Return on Equity undergoes declination. It has been found from the calculation of paired sample t test on the period before and after the acquisition from the calculation from 6 tested ratios, 4 ratios heve no significant defferences, only Debt to Equity and Net Profit Margin ratio which have significant differences. It can be concluded that there are no significant differences to the company's financial performance before and after the acquisition on Bank Rakyat Indonesia, Tbk. Keywords : Acquisition, Financial Ratio, and Paired Sample T test


Objective To explore the value of PCR for analyzing the pathogenic spectrum of bloodstream infection(BSI) in children, and to provide a new thought for epidemiological survey of BSI. Methods A total of 100patients in PICU with suspected bacterial infections were included, and then performed blood cultivation(BC) and analyzed by 16S rDNA-PCR following by sequencing and BLAST. At the same time, the results of two methods were compared. Results Among the 100 specimens, the positive rate of BC and PCR are 11% and 23%, respectively.There was significant difference between the two methods(χ2=10.08, P0.05). Gram-positive bacteria and Gram-negative bacteria accounted for 65.2% and 34.8%, respectively, in 23 bacteria. The predominant pathogens were Staphylococcus epidermidis(26.1%), followed by Escherichia coil(17.4%). Conclusions Compared with BC, 16S rDNA-PCR and sequencing which provide a new way of analyzing the pathogenic spectrum of BSI might be effective for epidemiological investigation. The pathogens of BSI are mainly gram-positive bacteria in PICU, and Staphylococcus epidermidis is the most common one.


Glycolic acid was polymerized under vacuum in the presence and absence of nano sized clay. The added clay catalyzed the condensation polymerization which can be confirmed by recording FTIR spectroscopy and intrinsic viscosity (IV) values. The relative intensity of C=O/CH is increased while increasing the amount of clay. DSC showed the appearance of multiple endotherms of poly(glycolic acid). TGA showed the percentage weight residue remain above 750°C for polymer-nano composite system was 21% and hence proved the flame retardancy (char forming) nature. TEM confirmed the nano size of the clay used to catalyze the condensation reaction. The intrinsic viscosity value was increased with the increase of percentage weight of Hectorite type clay.


Lesehan Sego Wiwit Prambanan Restaurant is a company engaged in the field of culinary in Prambanan. Lesehan Sego Wiwit Restaurant is a restaurant with traditional culinary of Central Java. This research discuss about the promotion strategy of Lesehan Sego Wiwit Prambanan restaurant in increasing the number of consumers in 2016. As a company that engaged in the field of culinary, Lesehan Sego Wiwit Restaurant of course has some ways to increasenumber of consumers, and one of those ways is formulating the strategy with effective ways. The aims of this research is to describe the promotion strategy that done by Lesehan Sego Wiwit Restaurant in increasing the number of consumers in 2016.
The method used is descriptive with qualitative approach of data collected through indepth interview supported by analysis technique which is done by collecting data, analyzing data and draw conclusion
The result showed, that the srtaregy undertaken by the Restaurant Lesehan Sego Wiwit Prambanan in palanning it using effective communication which has eight programs. Implementation is done by using the media internet and social media such as fanpage facebook and website. The most promotional mix influential in the promotion is to use direct discount (sales promotion) futhermore, the evaluation phase in carried out by holding regular meetings every six monthly.


Angular distributions in stripping reactions on Cd/sup 111/, Sn/sup 117/ , and Sn/sup 119/ were studied at deuteron energies of 13.6 Mev, and spins and parities of Cd/sup 112/, Sn/sup 118/,andSn/sup 120/ were measured in order to verify the data of G. R. Satchler (Ann. Phys. 3, 275, 1958). (R.V.J.)


Novel benzo[f]quinoxalino[2,3-β]porphyrin carboxylic acid (ZnBQA) and cyanoquinoxalino[6,7-β]porphyrin carboxylic acid (ZnQCA) have been synthesized to evaluate the effects of the π-elongation and the fused position of quinoxaline-fused porphyrins on the optical, electrochemical, and photovoltaic properties. ZnBQA showed a split, red-shifted Soret band relative to that of quinoxalino[2,3-β]porphyrin acid (ZnQMA), while the Q bands are rather blue-shifted. On the other hand, both Soret and Q-bands of ZnQCA are red-shifted compared to those of ZnQMA. The optical HOMO−LUMO gaps are consistent with those estimated by density functional theory calculations. The photovoltaic properties were compared under the optimized conditions in which a sealed device structure with TiCl4-treated, TiO2 double layers was used. The ZnBQA cell exhibited a relatively high power conversion efficiency (η) of 5.1%, while the ZnQCA cell yielded a low η value of 0.80%. Both of the η values are smaller than those of reference cells un...


Dubin–Johnson syndrome (DJS) is a recessive inherited disorder characterized by conjugated hyperbilirubinemia. It is caused by dysfunction of adenosine triphosphate‐binding cassette, sub‐family C, member 2 (ABCC2/MRP2) on the canalicular membrane of hepatocytes. We performed mutational analysis of the ABCC2/MRP2 gene in a Japanese female with DJS. Furthermore, we investigated the effects of the two identified DJS‐associated mutations on MRP2 function. We found a compound heterozygous mutation in the patient: W709R (c.2124T>C), a missense mutation in exon 17, and R1310X (c.3928C>T), a nonsense mutation in exon 28. DJS‐associated mutations have been shown to impair the protein maturation and transport activity of ABCC2/MRP2. We established HEK293 cell lines stably expressing one of the two identified DJS‐associated mutations. Expressed W709R MRP2 was mainly core‐glycosylated, predominantly retained in the endoplasmic reticulum, and exhibited no transport activity, suggesting that this mutation causes deficient maturation and impaired protein sorting. No MRP2 protein was expressed from HEK293 cells transfected with an R1310X‐containing construct. This compound heterozygous mutation of the MRP2 gene causes dysfunction of the MRP2 protein and the hyperbilirubinemia seen in DJS.


Leisure should be part of the daily life of the population, as guaranteed by the Federal Constitution (Brazil, 1988), however, not everyone has access. It is a qualitative research with a focus group approach with eight participating professors. The main findings were that leisure time experiences should not be related to work, as leisure is the distance from obligations, it is physical and mental rest. Main experiences in leisure time are: bathing, traveling, watching movies, reading, physical exercise and listening to music. Leisure is fundamental to the teacher's health, as reports of illness are increasing in this population.


This study compared the efficiency of the multigroup method to the finite-element-with-discontiguoussupport multigroup method (FEDS) for discretizing the energy domain for radiation transport simulations. FEDS is similar to multigroup in that the energy domain is first partitioned into coarse groups, but is different than multigroup in that it further partitions the coarse groups into discontiguous energy elements within each coarse group. This paper presents a procedure for propagating uncertainties for FEDS, followed by two verification problems to test if the uncertainty propagation routines were implemented correctly. The absolute error in the verification problems were 6 × 10−8 and 5 × 10−8, respectively. Next the paper uses two criticality benchmarks which demonstrate that FEDS converges faster than multigroup to an energy-resolved solution. The absolute error in the two validations problems were 2 × 10−4, and 4 × 10−3, respectively.


The author presents a novel table to determine the number of roots of a real polynomial in the right half of the complex plane. The new table is based on the Sturm theorem and Routh theorem. The table presents some advantages: it is fast and also the robust stability of linear time invariant systems with parametric uncertainty is possible to determine necessary and sufficient conditions by means of "Sign Decomposition" (C. Elizondo-Gonzalez, 1999; 2000; 2001).


Properties of nonrecursive filters appropriate for noise shaping coders and oversampling data converters are presented. When the noise shaping filter has optimal minimum phase, the number of quantizer levels required for loop stability is also minimized. Just as with infinite impulse response (IIR) noise shapers, the channel tones can appear in the baseband. These tones are diminished if at least one passband zero is reflected outside the unit circle. However, the filter is no longer minimum phase. This substantially increases the number of quantization levels required for stability. A better alternative is to use proper dithering in conjunction with a minimum phase filter. A stability test is derived which takes the dithering into account.<<ETX>>


Abstract The formulation of a physical problem in terms of a variational (or action) principle conveys significant advantages for the analytical formulation and numerical solution of that problem. One such problem is ice-sheet dynamics as described by non-Newtonian Stokes flow, for which the variational principle can be interpreted as stating that a measure of heat dissipation, due to internal deformation and boundary friction, plus the rate of loss of total potential energy is minimized under the constraint of incompressible flow. By carrying out low-aspect-ratio approximations to the Stokes flow problem within this variational principle, we obtain approximate dynamical equations and boundary conditions that are internally consistent and preserve the analytical structure of the full Stokes system. This also allows us to define an action principle for the popular first-order or 'Blatter–Pattyn' shallow-ice approximation that is distinct from the action principle for the Stokes problem yet preserves its most important properties and elucidates various details about this approximation. Further approximations within this new action functional yield the standard zero-order shallow-ice and shallow-shelf approximations, with their own action principles and boundary conditions. We emphasize the specification of boundary conditions, which are problematic to derive and implement consistently in approximate models but whose formulation is greatly simplified in a variational setting.


Background: The global population continues to rise at different rates in different parts of the world. While some countries are seeing a fast population increase, others are experiencing population loss. Significant ramifications of such changes in the global population distribution would be felt, as they are critical for meeting the Sustainable Development Goals (SDGs), or we might say that rapid population expansion poses obstacles to sustainable development.
Estimating the population size and composition by age, sex, and other demographic parameters is crucial for analyzing the country's future influence on poverty, sustainability, and development. This study tries to look at these parameters covered by the National Family Health Survey- 5 (NFHS 5) to see how accurate and trustworthy the predictors of district population size are.
Methodology: The study assessed the predictors of the population size of any district. It was conducted using the secondary data of phase 1 of NFHS-5. The outcome variable is the population of each district. Household profiles, literacy among women, their marriage and fertility, contraceptive usage, and unmet need for family planning were considered to assess their potential as a predictor of the district's population size. Principal component analysis (PCA) was conducted to identify the predictors.
Result: PCA was conducted on 18 variables, resulting in 7 principal components. Cumulatively, these components explained 77.6% of the total variation in data. On multiple linear regression, four principal components were found significant and these were related to women's literacy, contraceptive usage, early pregnancy, the marriage of fewer than 18 years, and those using health insurance.
Conclusion: Thus, women's literacy plays a pivotal role in determining a region's population size.


The rise of cardiovascular disease (CVD) as a leading cause of medical morbidity and mortality worldwide has long been thought to be a consequence of industrialization.1 As industrialization has spread globally, CVD has risen as a worldwide cause of illness and death. Diets higher in saturated fat and salt, sedentary lifestyle, tobacco use, and obesity, known cardiovascular risk factors, all appear to accompany industrialization. However, it is unlikely that a "return to nature" will solve the CVD problem. A positive consequence of industrialization is a longer life expectancy in part as a result of a more stable food supply, modern control of infectious diseases, and reduced perinatal morbidity. Because CVD has a long incubation period, perhaps the most potent cardiovascular risk factor is age. One "cause" of higher disease rates may be simply living long enough to acquire heart disease.

Article see p 245

If the oversimplifications above told the entire story, CVD rates would affect the population equally across all social strata and in all countries. However, this is not the case. After age, the second most ignored cardiovascular risk factor is socioeconomic status, with those at the lower end of the spectrum having dramatically higher rates of CVD.2 Although the upper classes might have been the first to experience the rise in CVD rates early in the course of industrialization, the lower classes have suffered disproportionately as industrialization progressed.1 In analyses structured to emphasize the impact of socioeconomic status on risk, the gradient from the lowest to the highest classes may be as much …


Purpose . The purpose of the article is to analyze the anti-etiquette forms of communication in the novel J.D. Selinger "The catcher in the rye", which provided for solving the following tasks: 1) to find out the basic approaches to the definition and refinement of the concept of "anti-etiquette forms of communication"; 2) characterize the forms of anti-etiquette communication; 2) classify them on a semantic basis. Methods of research: analysis and synthesis, inductive and deductive methods have allowed theoretically to comprehend modern research approaches to the formation of anti-etiquette speech behavior of the individual; the method of continuous sam-pling and contextual-interpretation analysis was applied to the formation and processing of the research corps of the actual material. Results. The author classified the anti-etiquette forms of communication into invective, slang, parasite words, nega-tive-grade vocabulary, as well as characterizing the tendencies of speech formation of characters, namely, Colhild Holden, in the image of which J.D. Selinger clearly reflected the non-conformist attitude. Holden's behavior is a challenge to the non-spiritual existence of society and the conformism of the layman. It is proved that the writer's aesthetic views are manifested in his philosophical consciousness through the sensory knowledge of the world, contemplative and creative attitude of man to reality, in the subjective development of the environment through the state of spiritual-sensory euphoria, elevation, catharsis, spiritual enjoyment, etc. The peculiarity of the language picture of the world of J.D. Selinger is the innovative approach to manners of the narrative, the depiction of characters, their language, the way of representing reality, the attitude of the protagonist to life. The study found that anti-etiquette forms of communication acquire a bulky artistic-figurative subtext value, become semantically multidimensional. Most of them, characterized by semantic visage, are marked by social magnetization. The internal individual and authorial form of them is conditioned by the system-shaped Holden attitude to reality. Conclusions. The analyzed material allowed to classify anti-etiquette forms of communication in the following groups: 1. aggressive (directed to a person, used for drawing images); 2. explosive (lexical units aimed at the situation, used for expressing emotions); 3. invective; 4. slang; 5. parasite words. Thus, anti-etiquette communication manifests itself in stylistically reduced vocabulary, image, negative comparisons, etc.


The invention provides a temperature control shell for a lithium battery pack. The shell comprises a shell body and a cover plate arranged at the opening of the shell body, the shell body comprises an external layer of the shell body and an internal layer of the shell body, and the external layer and the internal layer are connected with each other, thus forming a cavity. Phase change materials are filled into the cavity to control the temperature. The temperature control shell has good temperature control effect and simple structure.


The EDA industry offers a wide variety of software licensing models. However, the definitions of these licensing models and their applicability is neither consistent nor commonly understood amongst the EDA vendor and user communities. This paper broadly characterizes each of the common software licensing models in the EDA industry, illustrates the selection of specific licensing models through a set of criteria and case studies, and proposes solutions to some of the common problems with the current software licensing models.