This study aims to identify the motif in woven bamboo products, construct community creative ideas to find the identity of motifs in woven bamboo crafts, and communicate the findings of motifs to users of woven bamboo products. Method of this research used participatory action research. The subject research are community of woven bamboo craftsmen in the Jepang Regency of Mejobo District, Kudus. The research stages were carried out by identifying woven bamboo motifs, negotiating the search for woven bamboo motifs, finding the format and implementation of woven bamboo motifs. The relationship between researchers and the community is reciprocal to conduct systematic investigations of each other and produce products with the identity of the Kudus city. The results of this research showed that the characteristics of the bamboo woven using basic weaving and braiding techniques, densely spaced strands and tight strand widths, as well as the natural color of bamboo. Exploration of woven bamboo motifs is carried out by craftsmen and researchers to determine the woven pattern and design of the motif in the form of Menara Kudus to provide product identity.


As a branch of architecture industry,curtain wall appeared not long before in China. Domestic curtain wall industry develops gradually as reform and opening-up proceeds and economy booms. From the primitive foreign technology to absolutely independent intellectual property rights and products RD presently,the technique level and production capacity of China curtain wall industry have been in leading position of the world. The economy take-off makes curtain wall industry get great progress. As one of the main materials of curtain wall,architectural glass has made significant development. Previously,it changed from single glass to insulated glass. Resources are limited,but the theme of energy-saving is eternal,more and more energy-saving products appeared recently. Nowadays,with the enhancing of energy saving awareness,Low-E glass is used more and more frequent.


dUTPase is an enzyme found in all organisms that have thymine as a constituent of DNA. Through evolution, humans have two major isoforms of dUTPase: a mitochondrial (mDut) and a nuclear (nDut) isoform. The nuclear isoform of dUTPase is a 164‐amino‐acids‐long protein containing three cysteine residues. nDut's starting methionine is post‐translationally cleaved, leaving four unique amino acids on its amino‐terminus including one cysteine residue (C3). These are not present in the mitochondrial isoform (mDut). Using mass spectrometry analyses of recombinant dUTPase constructs, we have discovered an intermolecular disulfide bridge between cysteine‐3 of each nDut monomer. We have found that these two residues stabilize a dimer configuration that is unique to the nDut isoform. We have also uncovered an intramolecular disulfide linkage between cysteine residues C78 and C134, stabilizing the monomeric state of the protein. Of note, both disulfide linkages are essential for nDut's enzymatic activity and dimeric formation can be augmented by the addition of the oxidizing agent, hydrogen peroxide to cells. Analyses of endogenous cellular dUTPase proteins confirm these differences between the two isoforms. We observed that mDut appears to be a mixture of monomer, dimer, and trimer conformations, as well as higher‐order subunit interactions. In contrast, nDut appeared to exist only in monomeric and dimeric forms. Cysteine‐based redox "switches" have recently emerged as a distinct class of post‐translational modification. In light of this and our results, we propose that nDut possesses a redox switch whereby cysteine interactions regulate nDut's dUTP‐hydrolyzing activity.


About the Author Introduction Vocabulary Pre-Test 1. What Is Motivation and Why Does It Matter? 2. What Are the Roots of Motivation? 3. Motivation to Begin a Lesson or Task 4. How Do We Encourage Students to Finish the Task? 5. A Model for Developing Motivation in the Classroom 6. A Model for Facilitating Motivation Glossary Vocabulary Post-Test Bibliography Index


Abstract:The winner of this year's prize is Annabel Williams's "Fantasias on National Themes: Fantasy, Space, and Imperialism in Rebecca West." The judge is Wai Chee Dimock, William Lampson Professor of English and American Studies at Yale University and editor of PMLA. Her books include Residues of Justice: Literature, Law, Philosophy (1996), Through Other Continents: American Literature across Deep Time (2006), Shades of the Planet (2007), and a team-edited anthology, American Literature in the World: Anne Bradstreet to Octavia Butler (2017). Other writings have appeared in the New York Times, New Yorker, Los Angeles Review of Books, and Chronicle of Higher Education. Her new book, Weak Planet: Literature and Assisted Survival (2020), was just published.


This paper comprehensive analyzed the key factors of regional logistics development. On the basis of these, the evaluation index system of regional logistics development was established. Then the measuring model was proposed based on the AHP, and the six typical regions were chosen as the evaluation objects. Finally, according to the evaluation results, a brief analysis was given and suggestions were presented.


ABSTRACT: This paper presents the ten papers from the Journal of Emerging Technologies in Accounting with the most Google Scholar citations. I find that nine out of ten papers from the 2009 list are on this 2011 list, suggesting that the most-cited papers are a relatively stable set at this time. Further, I find that the ten most-cited papers account for roughly 70 percent of the citations for the journal, to-date. Finally, over the last two years eight of the ten most-cited have at least as many citations as they did over the first five years of the journal and, for that eight, there were twice as many citations from 2009 to 2011, as there were from 2004 to 2009.


The effects of crystallographic texture and deformation microstructure on the flow stress anisotropy in aluminium are reviewed. The texture is measured by neutron diffraction and the textural contribution to the anisotropy is determined by model calculations. It was found that texture can have very large effects on the anisotropy. However, for most experimental conditions, texture effects alone cannot explain the observed anisotropy. In those cases the non texture part of the anisotropy is caused by microstructural effects, and the relation between development of macroscopically oriented microbands and the "microstructural anisotropy " is discussed. Finally the effects of various materials and processing parameters on the flow stress anisotropy, the texture, the microstructure and on the relative importance of texture microstructure effects on the anisotropy is discussed.


Serving every origin-destination pair with direct service would be unmanageable for a transit agency, so it relies on the willingness of passengers to transfer. However, a connection adds time, money, and discomfort to a trip, and many passengers are unwilling to make a transfer. This research develops a process for assessing the quality of transit service connectivity and comparing different improvement strategies. Previous research has explored passenger dissatisfaction with the transfer, also known as the interchange, and joint optimization of connecting routes. Three types of elements affect every transfer. System elements include fare policy and pre-trip information. Facility elements include elements like weather protection and enroute information. Service elements include span of service and transfer waiting time. Services generally have the most opportunities for improvement, especially for agencies that schedule many trips but which have not built them around connections. There are generally many opportunities for facility improvements; while expensive, the benefits to transferring passengers will accumulate quickly at well-used transfer facilities. There are fewer opportunities for improving system elements, but they have the potential to improve transfers throughout the metropolitan region. This research explores guidelines and standards for these elements of connectivity and a way to monitor their change. An application of the process to the Chicago Transit Authority (CTA) showed that the CTA could improve connectivity by lowering the price of the transfer; improving weather protection, en-route information, and concessions at the transfer facilities; and reducing transfer waiting time. The fare is likely to increase in the future, and this is an opportunity for eliminating the price of a transfer for many passengers without creating a drop in revenue. 47% of transferring passengers currently have no weather protection at their transfer facility. The majority of transferring passengers do not have access to waiting time information or shopping opportunities when they travel. Building shelters or covered walkways, posting more schedules, providing more up-to-date information, and leasing out more space to businesses would reduce these problems. The majority of transferring passengers make transfers that are neither coordinated nor to high frequency routes, and through modifications to schedules and service management, the transfer waiting time can be reduced for many passengers, especially those on low frequency routes. Thesis Supervisor: Nigel H.M. Wilson Title: Professor of Civil and Environmental Engineering Thesis Supervisor: Kenneth E. Kruckemeyer Title: Research Associate, Center for Transportation Studies


The invention relates to a reaction device for preparing lower olefins by converting oxides, which mainly solves problems of the prior art, such as inconvenient control of regenerator charcoal-fired degree, and unstable average activity of catalyst in a reactor. The invention solves the problems by using the reaction device for preparing lower olefins by converting oxides, wherein the device mainly comprises a reactor 1, a spent catalyst stripper 7, a regenerator 9, a regeneration catalyst sedimentation segment 11 and a regeneration catalyst stripper 12; if the average carbon deposit amount of the catalyst at an outlet of the regenerator 9 is higher than a predetermined value, the partial or full catalyst can be returned to an inlet of the regenerator 9 to perform regeneration again, the regeneration catalyst which reach the carbon containing request is stripped and then entering into the reactor 1 through a catalyst conveying pipeline 13 to mix with the present catalyst, thereby realizing the desired average carbon deposit amount, finally the catalyst is contacted with the material. In this way, the invention is useful in industrial production of lower olefins.


High-performance parallel computer architecture and systems have been improved at a phenomenal rate. In the meantime, VLSI computer-aided design (CAD) software for multibillion-transistor IC design has become increasingly complex and requires prohibitively high computational resources. Recent studies have shown that, numerous CAD problems, with their high computational complexity, can greatly benefit from the fast-increasing parallel computation capabilities. However, parallel programming imposes big challenges for CAD applications. Fully exploiting the computational power of emerging general-purpose and domain-specific multicore/many-core processor systems, calls for fundamental research and engineering practice across every stage of parallel CAD design, from algorithm exploration, programming models, design-time and run-time environment, to CAD applications, such as verification, optimization, and simulation. This journal special section will cover recent progress on parallel CAD research, including algorithm foundations, programming models, parallel architectural-specific optimization, and verification. More specifically, papers with in-depth and extensive coverage of the following topics will be considered, as well as other topics relevant to the design of parallel CAD algorithms and software tools. 1. Parallel algorithm design and specification for CAD applications 2. Parallel programming models and languages of particular use in CAD 3. Runtime support and performance optimization for CAD applications 4. Parallel architecture-specific design and optimization for CAD applications 5. Parallel program debugging and verification techniques particularly relevant for CAD The papers should be submitted via the Manuscript Central website and should adhere to standard ACM TODAES formatting requirements (http://todaes.acm.org/). The page count limit is 25.


The present invention relates to a production method using the SRF landfill waste and new MSW was pre-stabilization. The configuration of the present invention is put into the pre-processing stage for sorting, separating and crushed while removing the organic material and moisture contained in the waste to the waste and new fetch MSW obtained by drilling an existing landfill through the pre-stabilized stage of short-term odor and re-buried in the way to produce high-quality SRF to classify the quality combustible materials without harmful gas explosion hazard and these SRF production process, separate the good earth and sand or cheoljaeryu is removed fracturing of the discharge incombustible in the waste excavated landfill by performing the step of improving the soil by itself, while improving the pollution of landfills continue to be the method characterized in the invention to enable the production and SRF new waste brought.


The main purpose of this paper is to show an existing level from which economic transformation will lead to income inequality alleviation. It makes use of the Panel Smooth Transmission Regression (PSTR) of Gonzalez et al. (2005). Applied to panel of 19 African countries from 1960 to 2012, findings suggest that economic transformation will lead to income inequality alleviation only if it reaches the level of 10.8%. Below this level, 1% of economic transformation will increase income inequality about 1.3892%, while it will be reduced about 0.8183% above the level of 10.08%. African countries have therefore, to accelerate their economic transformation process to reduce the income inequality and enhance its economic growth by making it inclusive, durable and fair.


Aerial inner ballistics in the forcing period mainly studies the moving resistance of bullet forced into chamber,which have a great significance to do with study and maintenances of barrel natural life,ballistic maintenances of barrel in the firing period,intension calculating of barrel and bullet and bullet firing precision as well.Therefore,forcer computing which has no perfect method is very important.According to mentioned above,in this paper,the forcer modeling of aerial automatic weapon is discussed by the analyzing method which gains the values of forcer inosculates practicality.


Aim. The presented study aims to assess economic damage to the health care system caused by climate change in Moscow.Tasks. The authors examine methods for assessing economic damage to the health care system caused by climate change; describe research methodology; assess economic damage to the health care system caused by climate change in Moscow in 2010–2020.Methods. To assess economic damage, this study uses the method of calculating the cost of the disease and the methodology of the World Health Organization (WHO), which involves analyzing many statistical indicators of the health care system collected by national statistical agencies. The period of study is from 2010 to 2020.Results. Climate change in Moscow can cause significant economic damage, which varies depending on the number of dangerous weather events from 0.05 to 5.63% of Moscow's gross regional product (GRP) (7.78–471.87 billion rubles). The greatest economic damage was in 2010, when the number of days with dangerous weather events in Moscow exceeded 180 days.Conclusions. Significant economic damage to the health care system caused by climate change in Moscow manifested by dangerous weather events calls for an effective climate policy. Further studies should assess the city's current climate policy, focusing on the implementation of adaptation measures and recommendations for its improvement.


Objective The study was conducted to early detect natural focus and to control the incidence and spread of cholera by establishing a surveillance system in Guangxi.Methods Thirty selected areas were classified and managed,and the objects and tasks were confirmed and implemented;the surveillance results of 8 years were analyzed and evaluated.Results A total of 561 147 samples were tested during 8 years;the total detection rate of cholera was 0.051%,and the culture-positive rates in patients with diarrhea,suspected cases,high-risk population,water,food and other environmental samples were respectively 0.061%,0.032%,0.099%,0.055% and 0.115%.All Vibrio cholera isolated between 1999 and 2001 were epidemic strains or toxic strains,while between 2002 and 2006 all the Vibrio cholera strains were only isolated from environmental samples and 92.31% of them were non-epidemic or non-toxic strains.For the samples collected in the three types of areas,the culture-positive rates were respectively 0.061%,0.043% and 0.134%.All the first-reported cases in the three years when epidemics occurred were detected by the surveillance system,and 93.23% cases of vibrio cholera were detected at the diarrhea clinics.The majority of positive cases of Vibrio cholera were found in epidemic areas,where the culture-positive rate(0.378%) was higher than that in non-epidemic areas(0.005%).The overall positive rate was positively correlative with the epidemic intensity,which was consistent with the epidemic situation.Conclusion The sensitivity of case detection at diarrhea clinics has been improved.The data collected through the surveillance system reflected the true prevalence and provided effective directions to control policy making.It is urgently necessary to establish more diarrhea clinics and to make proper guidelines for implementing the surveillance in medical institutions at all levels.


In this paper we present a motion control method for mobile robots in partially known indoor environments based on integration of focussed D* search algorithm and dynamic window local obstacle avoidance algorithm. While focussed D* generates global path, dynamic window local obstacle avoider generates the admissible robot trajectories that ensure safe robot motion. A simple and efficient procedure to the selection of appropriate motion commands based upon alignment of acquired trajectories and global geometric path is proposed. The initial a priori knowledge is used about the environment in the form of the occupancy grid map that is incrementally updated in runtime. The algorithms are verified both by simulation and experiments with a Pioneer 2DX mobile robot equipped with laser range finder.


Abstract This article reports an empirical research project that investigated the ways in which people's commitment to Christian faith content influenced their ways of learning. The project was set in a context of theories of adult experiential learning, and took the concept of the processes of internalization and externalization as its major focus. Within this paradigm, the external nature of Christian faith content is emphasized, together with its potential to exert an authoritative influence that in turn affects a variety of aspects of human growth and development. A typology of four "ways of believing" is offered, whereas the final discussion relates these to issues of faith development and theological reflection.


The most likely pathogenic mechanism behind recurrent spontaneous abortion is a multifactor mode of inheritance. Since the fetal causes are usually ignored, it has been almost impossible to show that any treatment has an effect. The fetal causes of embryo loss include structural malformations that are incompatible with life and chromosomal aberrations at least. However, the latter is not considered to be the case with recurrent miscarriage. The heart is the first functional organ formed during higher vertebrate development. Cardiac abnormalities may have the most embryonic lethality in all of the developmental defects. GATA-4 is by far the most extensively studied gene controlling embryogenesis, and it is thought to have a dominant role in heart development. Since numerous mutations in GATA-4 have been recognized in a wide range of congenital heart diseases, we hypothesized that some mutations in the GATA-4 gene of the chorionic villous result in lethal cardiac defects and constitute the primary cause of death in the uterus. We screened GATA-4 in 50 chorionic villous samples from recurrent spontaneous abortion patients by direct sequencing. Two novel mutations (c.-156 A>C; c.998-1 G>A) were identified. These two mutations were not found in 60 unrelated chorionic villous samples from induced abortion subjects. As the c.-156 A>C was located in the 5' untranslated region, we speculate that it influences the expression of GATA-4 protein. And the c.998-1 G>A mutation was against to the "GT-AG rule" of splicing. These discoveries may lead to the identification of new genes involved in recurrent spontaneous abortion.


The invention provides a multi-party distrust-based password split managing method. The method includes the following steps of: multi-party management of a password data plaintext of a mobile device end: the password data plaintext is divided into a plurality of parts which are respectively stored in the mobile device end and a could end; and network data packet segmentation and combination: the plurality of parts are divided into a plurality of portions, and the plurality of portions are respectively stored on physical devices which do not trust each other. According to the method of the invention, one password is divided into the plurality of portions parts which are respectively stored in the plurality of physical devices which do not trust each other, and therefore, the security of the password data plaintext of a user can be ensured when any one party is under an attack; the splitting and combination of the password of the user can be realized through an existing network layer data packet splitting and combination mechanism, and therefore, the method can be compatible with existing applications, and an application preprogram which uses the password is not needed to be modified, and a service-end program of a relevant application program is also not needed to be modified; and the security of the integrate plaintext of the password data of the user can be greatly enhanced under the premise that the use habits of the user and the operating performance of the applications are not affected almost.


Antidiabetes is a treatment that is currently much needed for diabetics, because the cost of treatment is getting higher, so it is recommended to use herbs as an alternative treatment. This study aims to determine natural ingredients that have the potential as antidiabetic. The method used is a systematic review by collecting, analyzing and summarizing 25 journals with the publication year 2016-2021 with keywords namely Antidiabetes, Natural Ingredients, and In Vivo. The results of the journal analysis are Beluntas leaves 0.9 mg/20 gBW, Kecombrang leaves 100 mg/kgBW, Keji Beling leaves 300 mg/kgBW, Kembang Bulan leaves 5.14 ml/200gBW, Kenikir leaves 1400 mg/200gBW, Mango leaves 105 mg /kgBW, Pucuk Merah leaves 100 g/kgBW, Rambutan leaves 50 mg/kgBW, Sambiloto leaves 40 mg/kgBW, Breadfruit leaves 600 mg/kgBW, Avocado seeds 150 mg/kgBW, Kebiul seeds 51mg/20gBW, Green Coffee Beans Arabica 400 mg/kgBW, Dates seeds 10 mL/day, Pumpkin seeds 720 mg/kgBW, Okra seeds 5,46 mg/gBW, Areca seeds 750 mg/kgBW, Buni bark 200 mg/kgBW, Faloak bark 150 mg /kgBW, Surian bark 150 mg/kgBW, Bilimbi fruit 750 mg/kgBW, Purple Sweet Potato fruit 150 mg/kgBW, Papaya flower 200 mg/kgBW, Pineapple peel 250 mg/kgBW and Black Garlic tuber 300 mg/kgBW with this optimal dose can reduce blood glucose levels.


A structural and electrochemical investigation of dimerization and Baker-Figgis (rotational) isomerization in the tri-ferric-substituted silicotungstates has been undertaken because these phenomena are important in a large number of polyoxometalates. A single-crystal X-ray diffraction analysis of K4Na7[(β-SiFe 3 W 9 (OH) 3 O 3 4 ) 2 (OH) 3 ] (β1) has been carried out [α = 12.9709(7) A, b = 38.720(2) A, c = 21.4221(12) A, orthorhombic, Pbcm, R 1 = 8.48%, based on 13809 independent reflections]. The complex is isostructural with [(a-Si-Fe 3 W 9 (OH) 3 O 3 4 ) 2 (OH) 3 ] 1 1 - (al) except that the edge-shared W 3 O 1 3 caps in each [SiFe 3 W 9 (OH) 3 O 3 4 ] 4 - unit are rotated by 60°. Electrochemical measurements, performed in a pH 5 acetate buffer, indicate a positive shift in the Fe I I I -based peak potential (and no change for the W V I -based potential) upon going from al to its monomeric derivative [(α-Si(FeOH 2 ) 3 -W 9 (OH) 3 O 3 4 )] 4 - (a2) (-0,484′0.005 V and -0.474′0.005 V, respectively). In contrast, the peak potentials of the Fe I I I - and W V I -based redox processes of pi are both found at more negative values than its rotational isomer al. The absolute values of the reduction peak potential differences are 0.022 V for Fe I I I and 0.162 V for W V I .


The purpose of this paper is to classify Interbrand's Top 100 Global brands based on their logo design. Content analysis was used as the analysis tool in this study. It is a commonly used technique in corporate branding. All data, including brand logos, were collected from Interbrand's official website. This study used longitudinal data of 20 years (2001 to 2020) by Interbrand. During this period, 177 brands appeared in the Top 100 Global Brands list. Four major logotypes were observed. First, "Shape only Logos" are logos with distinct shapes and intensely work independently without using its brand name like Audi, Mercedes, Apple, McDonald's, and Nike. Second, "Text Only Logos" are logos made of simple and clear typography with a potent color combination like Samsung, Intel, Uber, and Nokia. Third, a combination of text and image represents the brands and logos, but the text is placed outside the distinct Shape like Amazon, Microsoft, Toyota, Cisco, LG, and Puma. Fourth, also a combination of text and image used to represent the brands and logos is made up of text inside a distinct shape like BMW, SAP, GE, UPS, Ford, Volkswagen, and Kia.


This discussion paper introduces some important issues regarding European nursing education, namely the career pathways available to nurse educators within the European Economic Area in the context of the Bologna declaration (1999). This paper outlines some nurse education literature related to European nurse education career pathways, complemented by a focus group of nurse educators from seven countries in Europe. The paper commences with a brief outline of some of the European networks in nursing and the Tuning Project. The literature review is conveniently summarised, although it is not critically analysed when compared with Davies' (2008) recent work. This paper is not a research paper, hence the details concerning the composition, content and analysis of the focus group were not disclosed. The paper points out that there is little published with respect to Bologna and nurse education. To some extent this is inevitable given the national structural higher education reforms that are required prior to any specific discipline implementing Bologna. A review of the nursing section on the Tuning website outlines the nature of these reforms, and the then state of play of 14 countries in 2005. These data have not been incorporated in this paper. Similarly, the impact of the accession countries of 2004 and 2006 has been neglected, particularly, with respect to mobility and the legacy and reform of 'Soviet' models of nursing education. The Europe of 2008– 2010 has a different flavour to that of the early part of the century and certainly that of the 20th century. In many countries, substantive reforms of both education and nursing education are emerging or have taken place, for example, the utilisation of the Tuning nursing competences in Denmark and the rapid implementation of graduate education for nurses in many former accession countries. It is in this context that nurse educators experience their career pathways, choice and restraints. Indeed, in some countries at the university level, one needs to distinguish between nurses who teach, those who teach nurses (who are not nurses) and those who are both qualified/experienced nurses and educators. This is a fast moving scene; although, the authors have appropriately reviewed some nursing literature to 2007/2008, they have neglected to consider the broader political and educational impacts of the Bologna declaration, Lisbon agenda (knowledge economy) and the Berlin communiqué, with respect to doctoral education. It is also difficult to discuss mobility of nurse educators without an acknowledgement of Journal of Research in Nursing ©2009 SAGE PUBLICATIONS Los Angeles, London, New Delhi and Singapore VOL 14 (2) 123–124 DOI: 10.1177/ 1744987108102083 R E V I EW


The aim of this work is to solve an optimization problem using the genetic method. This could be considered similar to the Traveling Salesman Problem (TSP), as the topic is route optimization. The study is based on the Formula 1 race calendar and the geographical location of the Grand Prix venues. The optimization was done in two ways, with an add-on of Microsoft Excel, Excel Solver, and a program written in MATLAB. Excel Solver is based on: examining the possible solutions taking into account the constraints, then selecting the one that fits the most. The program written in MATLAB uses methods used in the genetic algorithm, such as selection, mutation, crossover and insertion.In this work, the results obtained in the two programs are compared and summarized. The Traveling Salesman Problem has been used many times to solve problems, but for this specific problem it has not been used yet.


Patient-reported outcome is a way to evaluate the clinical effectiveness through searching for patient relevant health data.The definition and the studying significance of patient report outcome are introduced,relevant patient report outcome instruments is gained by researching the documents,and the thoughts on patient report outcome applying to the clinical effectiveness assessment of traditional Chinese medicine are proposed.


Abstract— Thin films from low‐density networks of single‐walled carbon nanotubes (SWNTs) are intriguing new two‐dimensional electronic materials because they have excellent tunable electrical, optical, and mechanical properties. Such properties coupled with room‐temperature deposition from solution ensure that the material will have profound impact on emerging technologies such as cheap, flexible plastic electronics and smart fabrics and windows. These optoelectronic properties of SWNT thin films make them a potentially good replacement for indium tin oxide (ITO), used widely in photovoltaics, organic, and inorganic light‐emitting diodes, displays, touch screens, and smart windows.


As the world population exponentially grows, food production must increase to supply adequate nutrition to meet basic needs and optimize health outcomes. Developing economies around the world are expected to increase in both size and wealth as the population continues to rise, creating a global demand for dairy products due to their nutritional value, flavor, and affordability (United Nations 2013). Dairy products are a feasible means to help meet the demands of a growing world market as well as the nutritional needs of the globalpopulation.Forinstance,dairyproductsprovideanadequate source of protein that can help meet daily protein requirements to maintain positive protein balance and prevent muscle loss. Dairy proteins are of the highest quality and are considered complete proteins that contain all essential amino acids necessary to support muscle growth and maintenance. Dairy proteins such as whey and casein, derived from milk, have been shown to be superior to other protein sources in stimulating and improving muscle protein synthesis under both resting and exercise conditions (Burd and others 2012), allowing dairy to be considered an optimal protein source for regulation of muscle mass throughout the human lifespan. In addition to the role dairy proteins play in daily muscle protein synthesis, additional benefits in bone and metabolic health have been attenuated by the consumption of dairy products. Dairy products (milk, cheese, and yogurt) and their milk proteins, when consumed as part of a higher protein diet, have been shown to promote satiety (Lorenzen and others 2012), enhance glycemic regulation (El Khoury and others 2014), reduce blood pressure (Machin and others 2014), and improve body composition by preserving or increasing lean muscle mass and enhancing the reduction of fat mass during weight loss and maintenance (Josse and others 2011). Also, when consumed as part of a higher-protein diet, dairy has been shown to further enhance calcium retention and bone integrity due to the high-quality protein and calcium content of dairy products (Thorpe MP and others 2008), thereby resulting in greater long-term bone health. These metabolic and health advantages of dairy protein have led the global food and beverage industry to isolate or concentrate the protein components from milk to incorporate as value-added ingredients in a variety of different food and beverages. Dairy proteins are versatile and used by product developers to produce


Aim: The aims of this study were to evaluate the health-related quality of life (HRQOL) and make the treatment decision less difficult. Methods: Between 2007 and 2009 radical retropubic prostatectomy (RRP) was performed in 96 patients and permanent prostate brachytherapy (PPB) in 88 patients at our hospital. The general and disease-specific HRQOL was measured using two instruments, the Medical Outcome Study 8-Item Short-Form Health Survey (SF-8) and the expanded prostate index composite (EPIC). Results: Comparing RRP and PPB, there were significant differences in all scores except for general health in the 1st month after treatment which had the same score in both groups. The baseline quality of life scores in physical function (p < 0.05), physical role (p < 0.01), social functioning (p < 0.01), emotional role (p < 0.01) and mental health (p < 0.01) showed significant differences between the group and were better in the PPB group than in the RRP group. The physical component summary score in the PPB group was better than in the RRP group in the 1st month (p < 0.01) but recovered up to 3 months in the RRP group. The urinary bother and irritative/obstructive scores in the 1st month were worse from baseline in both groups (p < 0.05) and remained significantly worse up to 6 months in the PPB group than in the RRP group where these scores recovered within3 months. The urinary incontinence score in the RRP group was still worse than in the PPB group up to 12 months (p < 0.01). Bowel function and bother were significantly better in the RRP group at 3 (p < 0.05) and 6 months (p < 0.01) than in the PPB group where bowel function at 12 months was worse than at baseline and in the RRP group. Sexual function (p < 0.01) and sexual bother were better in the PPB group and did not change until 12 months. Conclusion: The difference in disease-specific quality of life has become clearer using EPIC. As with other published studies, our results provide important information that will therefore be useful for selecting the optimal treatments for localized prostate cancer.


Alkylphosphate self-assembled monolayers (SAMs) were prepared on Nb-doped SrTiO(3) (Nb-STO) conducting metal oxide substrates. Unlike thiols on gold, the alkylphosphate SAMs on Nb-STO exhibited an electrochemical stability over a wide voltage range from -2 to 2 V. Cyclic voltammetry showed that the SAM modification inhibited the electrochemical activity of the underlying conducting substrate with an efficiency dependent on the chain length. Impedance spectroscopy showed that SAM-modified Nb-STO substrates have a significantly higher resistance than bare substrates.


Modem measurement systems being implemented in power systems worldwide provide the unprecedented possibilities of analyzing the electromechanical transients and especially the oscillatory processes. As the communication and data processing technologies are being advanced at a quick pace, the possibilities of detecting and characterizing the low-frequency oscillations, which may threaten the power system stability and reliability, grow even wider. The two methods of timely detecting the oscillatory components have been developed on the basis of the approaches commonly utilized for solving the relevant tasks — the discrete Fourier transform and the Prony transform. The basic features of the methods are described and they are compared in terms of results quality and speed of operation for subsequent on-line application.


Museums have never been neutral. Public museums and exhibitions that originated in colonial times are accused of passing on biases that feature Euro-centric interpretations of history. This paper investigates the nature of bias and the history of museums and their biases, and then focuses on the representation of China in the British Museum as an elaborate case study. The paper argues that from the British Museums virtual collections and public resources, the descriptive text and collection highlights in the China galleries reflect implicit and biased historical perspectives of China in the UK, exhibiting a contrast between the British appreciation of exotic Chinese art and contempt towards Chinas social status arising from colonial trade. This paper provides a specific statement and analysis of western biases for colonial discussions and could contribute to decolonization actions taken in museums.


The apparent thermal conductivity of a polyatomic or isomerizing gas (as measured in a given apparatus) may decrease at low pressures for two distinct reasons. There may be accommodation effects at boundary surfaces, and there may be relaxation effects arising because molecules with excess energy do not yield it up fast enough to maintain local "chemical" equilibrium. If the apparatus is such that the temperature is measured at points in the gas and not in the walls, relaxation effects may be observed directly, and accommodation effects are (in the absence of relaxation effects) absent. A detailed analysis is made of the apparent thermal conductivity measured in such an apparatus with cylindrical symmetry. Expressions are obtained in closed form. Numerical calculations show that, for a gas of relatively long relaxation time in an apparatus of reasonable dimensions, the apparent thermal conductivity would decrease appreciably at readily-attained pressures.


: The aim of the current research is to present A Diagnostic Test of Children with a Learning Disabilities in Pre-academic English Language Sills of the Early Childhood Stage and the researcher used the descriptive approach to determine the items of that diagnostic test، its validity and reliability were confirmed, and the researcher recommended emphasizing the importance of using a pre-academic diagnosis test for children with a learning disabilities. In English language skills in early childhood for the competent authorities such as: (Ministry of Education, Department of Kindergarten).


Present study examined the relationship between perceived stress, emotional intelligence and self-efficacy among nursing students during the COVID-19 Pandemic. The questionnaires used were the PSS (Perceived stress scale) to measure perceived stress, the Emotional intelligence scale to measure emotional intelligence and SES (Self-efficacy scale) to measure self-efficacy, the data has collected from 120 nursing students from south India. Descriptive correlational research design was used and convenient sampling technique was employed to select the sample. The results showed that there is a positive correlation found between emotional intelligence and self-efficacy among nursing students during the pandemic. On the other hand there is no correlation found between emotional intelligence and Perceived stress. Also self-efficacy and Perceived stress is not found to be correlated among nursing students which shows the emotional intelligent and self-efficacy is not helping them to manage stress during the pandemic. Meanwhile according to the finding the emotional intelligence would help them to have more self-efficacy.


In 1974, producer Hulki Saner hired acclaimed director Metin Erksan to direct an unofficial remake of William Friedkin's The Exorcist (1973). The resultant film, ?eytan, took the plot, characters and set-pieces from the prior film and translated them into a predominantly Islamic setting. This process of intercultural dialogue exemplifies Yesilcam, a cycle of low-budget cinema from Turkey that flourished throughout the 1960s and 1970s in which elements of Western popular culture were being borrowed and remoulded into the Turkish context. Drawing on Tom O'Regan's model of cultural exchange and transmission, this article seeks to build a model of intercultural dialogue attendant to the underlying tensions and negotiations within this hybridised cultural text, an issue of particular contemporary resonance at a time when the EU is proposing 2008 as the 'Year of Intercultural Dialogue' and Turkey is itself in talks over its accession to the EU. Building upon that oft used model of Istanbul as a 'cultural bridge' between East and West, this article shall examine how Turkish cinema of the 1970s drew upon and appropriated elements from US popular culture. While ?eytan has been dismissed by some cultural commentators as derivative plagiarism, this article argues for a more nuanced model of cross-cultural exchange based around dialogue and interaction, attendant to the interstitial relationships through which cultures meet and interact.


The present invention is in-situ fibrillation method of recovering waste thermoplastic plastics. Washed and dried waste thermoplastic engineering plastics and waste thermoplastic common plastics aremixed in certain ratio; the mixture is molten, extruded and stretched in selected technological conditions; and the stretched material strips are forced cooled in cooling water tank and pelletized toobtain the in-situ reinforced and toughened plastic alloy with excellent comprehensive performance. The said production process has low cost and high production efficiency, solves the environmental pollution caused by waste plastics and utilizes the resource of waste plastics in high additional value.


We previously reported a long-term potentiation (LTP)-like facilitation invivo, known as synaptic plasticity, through GABA A receptor blockade by bicuculline in the mouse dentate gyrus, and protein expression profiles in the hippocampus of mice overexpressing human APP with the E693∆ mutation (APP OSK -Tg) as Alzheimer's disease model showing impaired synaptic plasticity. In this study, we investigated whether bicuculline ameliorated impaired synaptic plasticity, and analyzed its mechanism involved with this improvement by proteome analysis. Electrophysiological study showed that the LTP-like facilitation in vivo induced by bicuculline was significantly greater than impaired tetanic LTP in APP OSK -Tg mice, which was improved by bicuculline. Proteomic analysis showed that significant changes 8 h after bicuculline application in expression of 11 (9 up- and 2 downregulated) proteins in the hippocampus of APP OSK -Tg mice. The identified proteins could be functionally classified as chaperome, cytoskeletal protein, energy metabolism, metabolism, neuronal development, and synaptic component. Thus, these results show that bicuculline improves impaired tetanic LTP in the dentate gyrus and changes the expression of proteins in the hippocampus of APP OSK -Tg mice. We propose that the improvement of impaired synaptic plasticity through GABA A receptor blockade could be mediated by alterations in expression levels of these proteins.


Objective:To explore the effect of bone marrow stem cell mobilization in resolution of deep vein thrombosis.Methods:The SD adult rats were randomly divided into normal,sham,surgical and mobilization group(with subcutaneous injection of rhG-CSF).The peripheral blood mononuclear cell count,pathological change and thrombus organization rate in different time were examined.Results:The peripheral blood mononuclear cell count in mobilization group was significantly elevated,and there was no significant change in other groups.Compared with surgical group,there were more inflammatory cells in thrombus of mobilization group at 7th postoperative day,and the organization area of thrombus was wider and the organization rate was significantly different in mobilization group at 14th postoperative day(P0.05).Conclusion:The bone marrow stem cell mobilization contribute to the resolution of deep vein thrombosis.


The present invention relates to a microbial delivery of obesity related peptides. More particularly, the present invention relates to the use of genetically modified yeasts and / or lactic acid bacteria for food intake and / or energy homeostasis stimulation or delivery role neuropeptides and / or peptide hormones in inhibiting.


The invention provides a resistance test device and belongs to the technical field of agricultural machinery. The resistance test device comprises a frame, a walking device, an accommodation groove, a traction table, slide rails and a test device. The accommodation groove is arranged in the frame; the slide rails are arranged along the two sides of the accommodation groove respectively; the traction table is arranged on the slide rails; the walking device is arranged along one side of the frame; a driving motor of the walking device is connected to the traction table; and the test device is connected to the place, used for hanging a test part, of the traction table. During testing, the accommodation groove accommodates water or soil; the test part is connected to the traction table; and the motor of the walking device operates to drive the traction table to slide along the slide rails. The rotation speed of the motor is controlled through a control device, and the traction table is driven to slide along the slide rails through the motor and a tooth bar guide rail, so that working speed can be controlled and regulated automatically; and the resistance test device is simple in structure and convenient to operate. The tested resistance precision of the working part is high; and the test device is suitable for carrying out test on different agricultural machinery working parts under different soil and water quality conditions.


Molybdenum disulfide, MoS2, nanoparticles can be synthesized either at high temperature as mono- and polycrystalline materials or at low temperature using various (electro)chemical routes. In the work presented, MoS2 nanoparticles were obtained using a low temperature (140 °C) method via a chemical solution reaction route between the organometallic precursor Mo(CO)6 and sulfur in p-xylene. As obtained, the MoS2 nanoparticles of 10–30 nm diameter were mostly amorphous with a rounded shape. Upon annealing at 550 °C under vacuum, the nanoparticles lost their rounded shape and became slightly crystallized with curved (002) basal van der Waals planes (2H hexagonal structure). An increase of 2–4% in the d(002) spacing of the annealed MoS2 nanoparticles compared to polycrystalline MoS2 was observed.
The size and shape of these nanoparticles play an important role for their properties, e.g. in catalysis and lubrication.


In view of the limitation of signal dotting and phonetic communication device used for coal mine,a kind of flameproof signal dotting and phonetic carrier-current communication device especially suited to satisfy the current needs of modernization mine production with high-capacity and high-efficiency is designed,its effects and performance has been validated.


The main purpose of this paper is to explore the use of '-yo(- 요)' from the following perspective: 1) its grammatical category, 2) its origin, 3) its time of appearance and usage, 4) its distribution and types of combination in use, 5) the relation between its distribution and selectional restriction, 6) the semantic function of -yo, and 7) the underlying motivation of its frequent use in modern Korean. 1. '-yo(- 요)' primarily serves the function of a particle, especially in a spoken form. The secondary function of -yo has something to do with syntactic and pragmatic uses. 2. Morphologically, -yo as a particle[a word of addition] serves two grammatical functions: a auxiliary postposition added to the nominal and a sentence ender added to the verbal. In other words, it is widely used as postposition, ender, or suffix, which all reflects the agglutinative characteristic of Korean well. 3. -yo is used to serve a variety of syntactic and pragmatic functions: 1) question, 2) exposition, 3) exclamation, 4) order, 5) asking, 6) emphasis, 7) humbleness, 8) half-talk, 9) assertion, 10) listing, 11) pause, 12) connective, 13) presupposition/prediction, 14) phatic, 15) softener, 16) familiarity, 17) no propositional meaning, 18) turn continuation and 19) sentence ender. 4. -yo, a non-independent word, has little or no propositional meaning. As a additional particle, however, it conveys various semantic functions in a given context. Its use makes the conversation much more lively singalling a lots of interactional functions. 5. The frequent use of -yo in modern Korean is: 1) informality [casual style] - avoiding formality, 2) familiarity (closeness) - narrowing down the relational distance in conversation, 3) softness - signifying the flexibility in conversation, 4) spoken-oriented - structurally more productive in a spoken form. and 5) additional nature - showing a strong agglutinative nature added to various word or sentence combination. 6. The main goal of the present paper is twofold: to explore the exact semantic use of -yo and to make the suggestion that its mistaken abuse be avoided. In a word, this paper is for educational purpose by providing the proper uses of -yo in terms of its essential meanings. This is all for the correct use and expression of Korean especially in educational environment.


The utility model relates to a hybrid dust collector, wherein the shell is provided with a medium inlet, a medium outlet and a dust discharge outlet thereon, as well as an electrostatic dedusting device therein. The medium inlet, the medium outlet and the dust discharge outlet are respectively located on the top, the side and the bottom of the shell. The inside part of the shell is provided with an electrostatic dedusting plate and a cyclone spiral leaf from outward to inward, the upper end of the cyclone spiral leaf is communicated to the medium inlet, and the lower end thereof is connected with the dust discharge outlet. The upper side of the inner cavity of the shell is provided with a water spray device. The bottom of the shell is provided with a spray water outlet, which is communicated with the water spray device via an aqueduct, a water storage tank and a power pump. The utility model has the functions of cyclone dedusting, electrostatic dedusting and water bath spray in one system and has the advantages of simple and compact structure, convenient installation, regulation and maintenance, low energy consumption of operation cost and effective dust removal, which can be widely used in dust removal for industrial flue gas and other mediums.


In this paper, nonlinear variable structure control systems are considered, and a dynamic sliding mode compensator is proposed. It makes it possible to design nonlinear variable structure control systems with parameter variations and disturbances. In some cases, control laws can be designed simply.


A brief resume is given of research done on the bee using radioisotopes. The labeling of the bee with radioactive gold, the radioresistance of the bee, the structure of the hive, and the food exchanges within the hive are the topics discussed. (J.S.R.)


Cayuse News is your source for information on the new Mines proposal and award management system, called Cayuse. Progressive rollout to campus Summer/ Fall 2014 User testing and data integrity checking Spring/ Sum 2014 Legacy award and proposal data transfer Jan 2014 Cayuse Research Suite purchase Fall 2013 Software review by Deans, Res. Cou., CCIT & the Administration We will have better communications, easier transparency and greater accountability and tracking. Cayuse is a web-based platform for proposal and award management. From proposal development and submission to complete sponsored project lifecycle management and analytics, the Cayuse Research Suite will simplify research administration.


This paper makes a full analysis of the present situation and the knotty problems in the supervision on maintenance of the capital construction in university,and puts forward some measures for these problems so as to make rational use of the capital and reap the fullest benefits


In 2015, Revive & Restore [5] launched the Woolly Mammoth Revival Project with a goal of re-engineering a creature with genes [6] from the woolly mammoth and introducing it back into the tundra to combat climate change. Revive & Restore is a nonprofit in California that uses genome [7] editing technologies to enhance conservation efforts in sometimes controversial ways. In order to de-extinct the woolly mammoth, researchers theorize that they can manipulate the genome [7] of the Asian elephant, which is the mammoth's closest living evolutionary relative, to make it resemble the genome [7] of the extinct woolly mammoth. While their goal is to create a new elephant-mammoth hybrid species, or a mammophant, that looks and functions like the extinct woolly mammoth, critics have suggested researchers involved in the project have misled and exaggerated the process. As of 2021, researchers have not yet succeeded in their efforts to de-extinct the woolly mammoth, but have expressed that it may become a reality within a decade.


In order to study and evaluate the indirect immunofluorescent test and the ratio of CD41ymphocytes to CD� lymphocytes, '}7 cases of positive candida cultures were selected from among 400 patients referring to the hospital and suspected of candidiasis. In this study 39% of the patients had an antibody titer less than I: IIiO. No significant correlation was seen between canclidiasis and the results of the indirect immunofluorescent test. But, considering the site of isolation, the antibody titer was above I: 160 in all cases in· which candida was isolated from blood, whereas only4X'Y, of samples in which candida was isolated from urine had an antibody titer above I: 160; 7% of cases in which candida was isolated from the vagina had an antibody titer above I: 160. Patients suffering from systemic candidiasis had a decreased CD4/ CD8 lymphocyte ratio compared to normal subjects, whereas in vaginal and skin candidiasis, the ratio had not differed significantly. M.lIRI, Vol. 9, No.3, 205-208, 1995. INTRODUCTION MATERIAL AND METHODS Selection of patients and culture V"hll11l,Q NUlIlhcr'l rJII 1J7� N'ovcmt .... ·r r 'J'IS C.mdiua organisms are fungi yeasts that exist prcdomi IHUllly in a unicellular form. There arc more than IS()spccics of candida. but only 10 are regarded a., important pathogens for hum;.ms. TcchnicaJ adv<mccs have madl!derinitivespl!ci fication possible .within two days. Thl! incidence of diseasl! has increased in frequency over the past 20 years. and this may have been due to diagnostic methods. immunosuppressives ,md the "ppeanUlce of AIDS. thus highlighting tlte role oflymphoeytcs in host defense against this opportunistic infection. , Considering the import,mce of the role of cellular and humoral immunity in the prevention :md eradication of infection, we have undcnaken the study of the humoral response and CD4/CD8 ratio in patients infected with e,mdida. Fnlln mnong 4(}() patil!nlS refering 10 hospit,tls iLlTili:lteu to tlu; inUl Uni versity of Medical Sciences. and sllspectl!d or having candidiasis, a wtld of lJ7 c,lnuid,l-pnsilive sampks were iSlllatt.:d 1'1'0111 hlond. mint.:. vagina amI skin. D irec l and cuhun.; sample lests on two separah.! Illt.!dia. Sahouraud's dextrose agar :Uld Sahnur:lIJt.l's dexlmsl; ag:u' with Cydllhl..:x imide :Uld chlor.unphl..:nicol wl..: rl..: perfnrlTwd I'm all P,lt ients, If yeast growth was seen. it was transfern.:d Ul Cllnlllleal agar media with I IX! tween XO and supplementary tl..: sts including assimilation of carbohydrates and nitr:lll..:s. carhohydrate fermentation. urea hydrolysis and germ t uhl..: product it III test for species Liiagnosis were pt,;rfonned under sterile condi lions. Correspondence: A.A. Pourfalhollah. Immunology Dept.. School of Medical S(;icnccs. Tarbial Mod:lITcss University. P.O. Box )·tl55-lX�R. Tehran. Islamic Republic of Iran. 205 Indirect immunnl1uoresccnt test In this method suspensions of candida isolateu from eilch raticnt's culture were cuateu on slides a.-; antigen :U1d a Indirect It11lmrnofluorescence and CD4/CD8 in Candidiasis Table I. Frequencies of different species relative ttl Ihe area uf clinical infecliun Candida aibiculls Site of isolation No. % Urinary lraci inrct.:tion 18 58 Vulvovaginitis 21 75 Scpli(.;cmia 13 100 Esuphngitis 4 50


It is shown that the classical controllers for dead-time systems, known as Smith predictors, provide a suitable basis for the design of optimal robust stabilizing controllers. Only in the case of an unstable plant a modification of the Smith predictor is necessary. A simple first order dead-time system serves as an illustrative example.


Methods and techniques of calculating power series and function are diverse. It is a more difficult and higher skillful task for students. In the method for calculating the power series sum function, there is an interesting method of using the termwise integration. The students are confused about the lower limit of the integral selected as 0 in this method. This article discussed the reasons of the lower limit of integration is selected as 0 and the selectting scope of the lower limit of integration.


Aim : Aim of the study is to examine the profile of participants attending the outpatient of HHMH & R, Shimla. Material and Methods : Cross sectional analysis was done and patients attending the outpatient department of our hospital from Feb 2021 to Oct 2021. Results : A total of 668 patients attended outpatient of our centre during above duration. Diagnosis was confirmed as per DSM-V criteria by consultant psychiatrist. All details were collected and analysed by using SPSS version 20. Around 84% patients were males and 15 % were females. Majority of patients from 21-40 years age group and came by themselves. Most common diagnosis was substance use disorder (34%) followed by schizophrenia (16.91%), Bipolar disorder (14.6%). Conclusion: Majority of patients were from the middle age group which constitutes the most productive part of society which is of concern and most of them were not referred by anyone and sought help by themselves. Substance use contributes to majority of OPD which also implies to the upcoming epidemic of substance use.


Mango fruits have a short shelf life and hot water is considered as one of some techniques to improve general appearance and maintain fruits quality. The effect of postharvest applications of hot water treatments were applied to Diab mango fruits at the two successive seasons of 2015 and 2016. Hot water dipping (HWD) at a range of treated temperatures at 50°C or 45°C for 5 and 10 min were applied to mangoes cv. Diab after harvest and some were also left on control without hot water dipping. Both treated and untreated fruits (control) were stored at 10°C for 3 weeks and then ripened at 20°C for 7 days. The fruits quality properties (weight loss, decay percent, fruit firmness, ethylene production, soluble solid content (SSC), titratable acidity (TA) and ascorbic acid content) were investigated periodically for a storage period of 7 days for 3 weeks and after ripe at 20°C. the results clear that, Fruit loss percentage was lower in fruit treated with HWD treatments as compared to control (untreated) which having higher percent. On the other side, treated fruits indicated less weight loss at 10°C and higher weight loss in ripening at 20°C. Mango fruits dipped in hot water at 50°C or 45°C for 5 and10 min had no decay percent at 10°C of storage for one week. All HWTs achieved the highest value of firmness with significant differences compared with untreated fruits (control) at the end of storage period and ripening at 20°C Moreover, mango fruit which dipped in hot water at 50 C for 10 min showed firmer fruits than those dipped at 45°C. Mango fruits treated with hot water at 50°C for 10 min showed a little rise in production of ethylene during the storage period at 10°C and ripening at 20°C for 7 days. Fruits treated with HWD at 50°C for 10 min recorded the better content of soluble solid and the lower titratable acidity. In addition, significant decline in content of ascorbic acid was observed during storage period at 10°C as well as ripening at 20°C compared with a sharp reduction in control fruit.


The invention relates to a method for producing adhesive blanks with internal openings (3), from an endless band (1) comprising a support layer (4), at least one adhesive layer (5) and optionally a matrix layer (6), as well as to a blank produced according to said method. In order to produce a blank with an internal opening (3) without using a sucking punch, the internal opening contour (17) and the external contour (10) of each blank are punched one after the other in the adhesive layer (5) and optionally in the matrix layer (6), the external contour (10) having no common point with the punch line of the internal opening (3). Said support layer is removed with the punching residues from the internal opening (3) over a stripping edge and the rest of the band is transferred onto a protective film (8).


Previous numerical studies have focused on the direct impact of microphysics schemes on multiscale atmospheric systems that produce rainfall. However, the indirect impact of microphysics schemes on the key large‐scale circulation around areas of extreme rainfall has not yet been examined systematically. We used the ARW‐WRF (Advanced Research WRF (Weather Research and Forecasting) Model) to simulate the extreme rainfall event in Henan province, China from 19 to 21 July 2021. Experiments were conducted to investigate the sensitivity of the simulation to the three popular double‐moment microphysics parameterizations: the Thompson, Morrison and WDM6 (WRF Double‐Moment 6‐Class Microphysics Schemes). We found significant sensitivity to the microphysics parameterization, with the maximum precipitation varying by up to 400 mm and the area‐averaged precipitation by 33 mm. The Thompson and Morrison microphysics schemes produced the largest amount of precipitation, whereas the WDM6 scheme produced the smallest amount of precipitation. The simulated southerly flow varied substantially between the different microphysics schemes. This is due to the ability of the microphysics schemes to produce latent heat, which enhances the southerly flow, leading to more intense precipitation. The higher the parameterized latent heat, the stronger and more obvious the southerly flow over southern Henan province, with the WDM6 scheme simulating a much weaker southerly flow and the Thompson scheme producing the strongest southerly flow. These results indicate that the indirect effects on the key circulation patterns can be just as sensitive to the formulation of the microphysics scheme as the direct effects on extreme rainfall. These results may help to improve the prediction of extreme rainfall events.


The normalized cut criterion measures the total dissimilarity between the different groups as well as the total simila-rity within the groups.The algorithm and how to apply it to segmenting different kinds of images are introduced in this paper.Valuable experimental results are obtained.


Video copy detection is a complementary approach to watermarking. As opposed to watermarking, which relies on inserting a distinct pattern into the video stream, video copy detection techniques match content-based signatures to detect copies of video. Existing typical content-based copy detection schemes have relied on image matching. In this we try to implement a technique to detect copying of videos in distributed environment using content based fingerprints.


A general purpose computer performs mutual authentication with the external storage medium can be detachably loaded therein, is stored directly into its interior storing the external storage medium copyrighted loading the data from the given device. Internal storage means of the general-purpose computer, the HDD holds such data protected by copyright as music data. The memory card driver controls the memory card to store data from the HDD at the time of performing the direct mutual authentication with the memory card, the external storage medium, a successful mutual authentication. An external storage medium, the mutual authentication, the internal storage unit, the copyright, the memory card


Abstract This paper first summarizes the characteristics and distribution of water resources in China and then addresses the three major types of water problems from both historical and geographical perspectives. Major water problems, i.e. floods, droughts and water shortages, and water pollution, have tremendous impacts on the economic development and social well being in China. Analyses of water problems in the context of natural causes and human influences lead to the discussion of the role of the hydrological sciences in sustainable management of water resources, with an example of the preliminary findings of a study of water resources renewability in the Yellow River basin. Finally, challenges and opportunities for hydrologists are highlighted to present a brief summary and prospect on the development of the hydrological sciences in China.


A case of successful treatment of orbital echinococcosis without evidence of recurrence on prolonged follow-up is presented. The management of orbital hydatid cyst is discussed. ¿ 2000 The British Infection Society


Patient: Female, 67-year-old Final Diagnosis: Heart failure Symptoms: Chest pain • dyspnoea • poor exercise tolerance Medication: — Clinical Procedure: Intraoartic baloon pump insertion – new technique Specialty: Cardiac surgery Objective: Management of emergency care Background: The use of an intra-aortic balloon pump (IABP) in patients with advanced heart failure can provide interim mechanical support as a bridge to further treatment, including cardiac transplantation. The femoral artery, axillary artery, and subclavian artery are the main approaches to IABP catheter placement. A case is reported of the use of a left external iliac artery approach to IABP catheter placement using a subcutaneous channel in a patient with chronic heart failure. Case Report: A 67-year-old woman presented with a history of heart failure. She had New York Heart Association (NYHA) Functional Class IV symptoms. The patient had a history of chronic heart failure due to dilated cardiomyopathy with a left ventricular ejection fraction of 25%, severe mitral regurgitation, paroxysmal atrial fibrillation, and hypothyroidism. Immediate pharmacological treatment began, and an IABP catheter was initially inserted using femoral artery access. During 115 days of hospital treatment, several unsuccessful attempts were made to remove the IABP catheter. Due to prolonged patient immobility, the IABP catheter access was changed from the femoral artery to the external iliac artery. A prosthetic Dacron graft and a subcutaneous channel were used. Optimal pharmacotherapy commenced, and the patient underwent rehabilitation and mobilization with significant improvement in cardiac function. At 195 days after changing the IABP catheter access, the patient underwent successful heart transplantation. Conclusions: This report demonstrated that in a patient with chronic heart failure requiring long-term femoral IABP catheter placement, an external iliac artery approach using a subcutaneous channel provided a bridge to cardiac transplantation.


Su Shi,a wizard in the Chinese history,has been viewed as a great writer who knew numerous difficulties and setbacks in his life.Deeply influenced by the doctrine of Zen Buddhism,Su Shi filled his creation with the doctrine of Zen Buddhism.And his many poems were filled with the mentality of Zen Buddhism,such as"living or doing things accrding to the arrangement of fate" and "being detached from reality",expressing the philosophy of conforming to nature,showing disdain for misery and being sensible and optimistic.


The invention relates to a high-frequency coupler for connecting a coaxial plug (38) to a high-frequency transmission line on a printed circuit board (32). To this end, the HF coupler comprises at least one pair of spring lamellae (12, 14), which are arranged and designed for electrically contacting a middle conductor (40) of the coaxial plug (38), and comprises at least one second pair of spring lamellae (16, 18), which are arranged and designed for electrically contacting an outer conductor (42) of the coaxial plug (38), whereby at least one spring lamella (12, 14) of the first pair has, at an end facing away from the coaxial plug (38), a contact surface (24) for electrically connecting the HF coupler to the HF transmission line on the printed circuit board (32) and for mechanically connecting to the printed circuit board (32), and at least one spring lamella (16, 18) of the second pair has, at an end facing away from the coaxial plug (38), a contact surface (22, 26) for electrically connecting the HF coupler to a ground contact on the printed circuit board (32) and for mechanically connecting to the printed circuit board (32).


Liudprand of Cremona is among the most famous early medieval chroniclers. He learned Greek during his first stay in Constantinople in the late 940s and used it extensively in his various written wo...


Skin with acne, the presence of matrix degrading enzymes, such as MMP and neutrophil elastase, induction of neutrophils was found that with a decrease in procollagen biosynthesis. The present invention, by administering (i) and inhibitors of matrix-degrading enzymes, reduces (ii) inflammation, thus at least one of cytokine inhibitors that reduce the infiltration of neutrophils, locally or systemically, it is intended to treat inflammation associated with scarring and acne. Reduce matrix degradation, by the normal biosynthesis of procollagen again, to reduce inflammation, a skin with acne can be naturally restored. By inhibiting cytokine, relieve MMP is resident skin cells, also reduces inflammation leading to neutrophils from the bloodstream carrying MMP and elastase in acne lesions. By reducing the abundance of matrix-degrading enzymes in acne lesions, incomplete repair of the skin is reduced, scarring is reduced in skin with acne.


This article provides a comparative analysis of 2 experiments on procedures to increase the capacity of closely spaced parallel runways under low-visibility conditions. The common goal for both studies was to achieve visual meteorological capacity under instrument meteorological conditions, when landing aircraft on parallel runways 750 ft apart. Using a high-fidelity flight deck simulator, both studies investigated procedures related to breakout maneuvers on final approach during off-nominal conditions. The first study investigated procedures for 2 parallel runways (involving a leading and trailing aircraft) and the second study examined 3 parallel runways separated by 750 ft, investigating procedures for 3 simultaneously arriving aircraft (leading, center, and right aircraft). In both studies, off-nominal events were introduced during the approach. In some cases the wake of the leading aircraft drifted too close to the aircraft behind. In others, the leading aircraft deviated off its course and blundered toward the trailing aircraft. Statistical analysis examined the effects of approach echelon (2-runway vs. 3-runway), breakout cause, and breakout location on the dependent measures of breakout trajectory cross-track error, breakout trajectory track angle error, pilot workload, and pilot situation awareness. Although revealing differences between the study conditions, results also show accurate cross-track and track angle error levels (i.e., high levels of breakout trajectory accuracy), manageable pilot workload, and high levels of pilot situation awareness across all conditions in both studies. Results suggest possible avenues of future adaptation of dual and triple parallel runway operations (e.g., improving pilot training) and also show potential promise of the concept.


Scholars have explored many ways to rearrange risk outside of traditional insurance markets. An interesting literature addresses a range of innovative alternatives, including the sale of unmatured tort claims or chances at windfalls, "anti-insurance," or "reverse insurance," and index-based derivatives that address routine (but lifealtering) risks, such as those to home values or livelihoods. Because most of this work grows out of a conviction that specific risk allocations embedded in law could be improved upon, the merits of the newly proposed risk arrangements have taken center stage. This Article, in contrast, examines questions surrounding risk customization itself such as the optimal amount of stickiness in society's default risk allocations, the effects of heterogeneity in risk arrangements, and the implications (cognitive and otherwise) of Copyright @ 2011 by Lee Anne Fennell. t Professor of Law, University of Chicago Law School. For helpful questions, comments, and conversations about this project, I am grateful to Ian Ayres, John Bronsteen, Rosalind Dixon, Frank Easterbrook, Mark Fenster, Christopher Fennell, Louis Kaplow, Victor Goldberg, Jeffrey Gordon, Saul Levmore, Alison Morantz, Jonathan Nash, William Page, Mitchell Polinsky, Ariel Porat, Alex Raskolnikov, Daniel Schwarcz, Alan Schwartz, Steven Shavell, Michael Wolf, Michael Zimmer, and participants in presentations and workshops at Columbia University School of Law, Harvard Law School, Florida State University College of Law, Loyola University Chicago School of Law, Stanford Law School, Tel Aviv University Faculty of Law, the University of Chicago Law School, the University of Florida College of Law, the University of Illinois College of Law, and the 2008 Midwestern Law and Economics Association Meeting. I thank the Stuart C. and JoAnn Nathan Faculty Fund for financial support. Prisca Kim, Catherine Kiwala, and Eric Singer provided excellent research assistance.


A damper device based on shape memory alloy (SMA) wires is developed for vibration control implementation of large bridges as well as high rise buildings. The proposed damper was characterized by good energy dissipation mechanism and can be installed in the diagonal positions of the frame storey as well as below the main span of bridge decks. As a case study, two such SMA dampers were installed in a cable stayed bridge model to verify the effectiveness of the damper devices. The experimental results illustrate that the developed SMA dampers are very effective to reduce structural response and have great potential for use as efficient energy dissipation devices.


Spray drift models are commonly used to determine buffer distances between target areas (e.g., crops, forests) and non-target areas (e.g., streams, neighboring crops, urban areas). Most current modeling of spray drift uses a single droplet approach that treat the atmosphere around the droplet as if it were not influenced by other droplets. This lack of a 'neighborhood' or 'cloud' effect leads to the over estimation of evaporation as the elevated humidity caused by the other droplets in the droplet cloud is not considered. Here, we evaluate spray cloud thermodynamics in an effort to improve spray drift models. We compare pesticide drift models to dense gas models over a range of ambient meteorological conditions for simple spray configurations (i.e., one nozzle with zero crosswind). Models compared well for high relative humidity but diverged for low relative humidity. We attribute the divergence to an over prediction of droplet evaporative loss in spray drift models.


Background: Liver transplantation is a therapeutic modality in situations of advanced liver disease whose success depends on how patients deal with a new and complex therapeutic regimen in their daily lives. Objectives: To develop a flowchart to support nursing decision-making on the therapeutic self-management of liver transplant patients. Methodology: Qualitative longitudinal study conducted between January and December 2013 in a transplantation center, using retrospective content analysis of nursing records and consensus meetings with nurses. Results: The flowchart included the following areas: medication regimen, dietary regimen, lifestyles, and complications. Nurses reached a 90% consensus on the specifications of each intervention included in these areas, with the purpose of achieving continuity of care. Conclusion: The systematization of information in a flowchart allows for a better identification of each patient's needs with a view to preparing discharge, the continuity and quality of care.


Information on the biology and fishery resources of two common species of western Atlantic porgies, Calamus areli/rons and C. proridens, is compiled, reviewed, and
analyzed in the FAO species synopsis style. (PDF file contains 25 pages.)


High purity nanomaterials (silicon, tungsten carbide, oxides of silicon, tin, iron, titan) are widely used in the innovative and science-intensive fields of economy. In manufacture of these substances it is exceedingly important that a by-product of synthesis should not contaminate the target products or interact with process equipment. Otherwise it will take up an additional amount of impurities. A promising way to tackle with this problem is application of low-temperature plasma. It allows to create a set of modern apparatus with the minimum microimpurity background. The advantage of this technique is that it can yield nanodispersed powders which is virtually impossible with other high purity technologies.It is known that plasma allows receiving a various level of structural conditions. But difficulties of realization of the given conditions always rested against necessity of their instant fixing. However, it is possible only in cryogenic jets of hydrogen, nitrogen, oxygen, argon, helium, etc. Reactors used earlier had a lack of this possibility. Creation of a new class for cryogenic plasmachemical technologies for obtaining of the high purity nanomaterials was the purpose of the given work.During the researches there was examined the influence of the following 3 factors for the dispersion of the final product: the aggregate state of the original substance, the components ratio (heads of high-speed plasma jet and jet injected gas) and the speed of cryogenic tempering. Development of cryogenic plasmachemical nanotechnologies was spent on the basis of the CALS-technologies (Continuous Acquisition and Life cycle Support).


The deep demographic transformations that Brazil comes, with alterations in its age structure, must be subject of studies for reorientation of the public politics. The announced crisis, caused for the aging of the population, can be prevented with the qualification of the future force of work that is essential for the social and economic balance. The increase of the fecundity, fall of mortality, the demographic explosion, the increase of the life expectancy, the posterior fall of the fecundity, is boarded in the work with the objective to search an agreement of the process of population aging. Its may to call attention to use to advantage the demographic bonuses that we find in them today (population in productive age), and that through estimates goes to continue growing up to 2025, for we reevaluate the public politics and to break paradigms, giving priority at social and social security, education and health.


In this paper, I explored the significance of Samcheok Ohwa-ri mountain fortress, located in the southern cape at the mouth of Osipcheon which traverses Samcheok, in Shilla history. For this, I first analyzed archeological data and literary materials to prove that the Ohwa-ri mountain fortress was a Shilla fortress. With the archeological data, I was able to analyze the Shilla pottery excavated from the fortress and studied construction method at the earthwork walls with peeled stones and estimated that Ohwa-ri mountain fortress was a Shilla fortress from the fifth and sixth centuries. With the literary materials, I studied Shilla names around the Ohwa-ri mountain fortress and book records proved that Ohwa-ri mountain fortress was in fact a Shilla fortress. Because Ohwa-ri mountain fortress is estimated to be a Shilla fortress, this fortress can be regarded as the Siljik(ju) fortress specified in Samguksagi, and furthermore, a fortress where Silji-Dosa and Silji-Gunju of Uljinbongpyeongshillabi resided. As for the significance of the fortress in Shilla history, it most likely reflected the eastern coastal navigation of Shilla as it was located in the southern cape at the mouth of a river, and according to a more recent findings, connected with Gangmundong Shilla earthen fortress adjacent to Gyeongpoho, Gangreung. In summary, it is estimated that the general area of Ohwa-ri mountain fortress served as a port of call for coastal navigation in the process of developing routes between Shilla and Goguryeo along the eastern coast, and later, functioned as a defensive strongpoint as the two nations opposed each other. Because such historical function was signified, it is estimated that the general area of the Ohwa-ri mountain fortress was selected as a stage of Bile Mountain for jungsa in Bukhae during the Unified Shilla period.


Restructuring real property taxation has become a common strategy for reforming local public finance in many transition economies (Bird and Slack 2004; Malme and Youngman 2003). China is no exception. In 2003, the Standing Committee of the National People's Congress of China issued a general directive for creating a uniform property tax to consolidate numerous taxes and fees on real estate. Following the announcement, the central government proposed to combine the Building Tax 1 , Urban Real Estate Tax (URET) and Urban and Township Land Use Tax (LUT) into a single levy (see Appendix A for the definition of these taxes). 2 Immediately, this suggestion has generated many public inquires. 3 This paper deals with an important, yet currently overlooked, issue: How would the new property tax system affect the production and tax burden of industries in China? There are three reasons for choosing this topic. First, many policymakers have suggested that the proposed real property tax should, in its initial stage of implementation, be applied only to income-generating real estate, including factories, commercial offices and rental residential buildings. If the central government accepts this recommendation, 1 The Building Tax is also referred to as House Tax in the literature. 2 This information was obtained from interviews with senior tax officials from the State Administration of Taxation of China. There are other proposals as well. For instance, one unofficial suggestion is to include the land leasing fees in the property tax payment, which lessees would pay annually instead of a lump sum. Yet, government officials have been arguing against this idea. 3 Some of the most common questions include: 1. How would the proposed property tax system affect local public finance in general, and fiscal relations between different levels of local government in particular? 2. Which existing property related taxes and fees should be consolidated into the new unified tax? 3. How would the new tax on land and buildings be integrated with the existing public leasehold system (Hong 2005)? 4. Would the new property tax reduce real estate prices? If so, would real estate developers or homebuyers be major beneficiaries of price changes, thereby influencing the pace of property development and homeownership? 2 industries would be affected first by the property tax reform. Hence, it would be useful to assess how different policy designs would alter industrial production and tax burden allocation among sectors, both of which are the …


Alcohol and Drug Problems in Women is an excellent, well-organized book. Ambitious in scope, it is impressive in its accomplishment, which is to assess and report the state of knowledge about a badly neglected area, to clarify directions for further work, and to pose questions about why some beliefs persist and some areas are never studied. The book consists of 17 chapters, each extensively referenced with a summary by different authors on different topics. But it is more than a collection of papers. Dr Kalant's introduction and overview ties together the different sections and gives the whole coherence. Cohesion is further reinforced by the selection of authors and the framework of critical vision of the editorial advisory board of the Addiction Research Foundation, Toronto. The central point of the book is that drug and alcohol use and abuse are different for women than for men, that women's drug and alcohol use is important, and, because it is so little studied, we do not know much about it. The book avoids facile transmis¬ sion of unexamined assumptions and cheerfully and competently blasts some beloved myths. For example, Harry Levine's thoughtful historical essay on how women used the temperance issue both in its own right and as a lever to battle for larger political and econom¬ ic integrity is a pleasure; it is respectful of women and humane. In the chapter on sex differences in prevalence of problem drinking, Fer-


The presence of meconium at the onset of labour and its obstetric outcome was studied over a 3 month period. Out of the 1267 deliveries that occurred during this period, 100 (7.89%) had meconium staining of liquor. These were compared to the remaining 1167 patients with clear liquor. Monitoring included cardiotocography, scalp pH estimation when required and optimal care at delivery.The fetal heart rate abnormalities were more common in meconium stained patients. Thick meconium staining was associated with higher cesarean section rate, low Apgar score at one minute and more admissions to the neonatal intensive care unit.All women with meconium staining of liquor should be cardiotocographically monitored in labour and managed by optimal timely intervention in order to avoid severe asphyxia and meconium aspiration


In the post – genomic era the understanding of gene regulation has become a challenge and a research priority. In this research, we performed a comparative study of the regulator sequences of the chalcone synthase gene across plant families. Twenty-two sequences of chalcone synthase promoters were compared considering three regulator Cis elements: G-Box, H-Box and TATA Box. Our results show that these Cis elements are conserved among species and even at the family level. However, in some species all of the Cis elements were not found, showing that the expression and regulation of these promoters via the Cis elements can be variable. Additionally, a comparison between promoters from a species with a chalcone synthase multigene family showed that the duplicate genes are variable in the composition of the Cis elements, suggesting that these genes could be expressing in different ways.


The invention belongs to an alpine bolter miner back affiliating device, in particular relates to an alpine bolter miner back affiliating travel type breaking and transhipping continuous transporting device, and solves the problems that the back affiliating manner the existing alpine bolter miner is long in auxiliary time, production efficiency of alpine bolter miner is affected and potential safety hazard is existed. The device comprises a track travel type receiving transfer breaker, a large-span bridge conveyor and a rigid structure frame. The track travel type receiving transfer breaker comprises a receiving part, a breaking part and a discharging part. The large-span bridge conveyor is a bridge truss beam structure with adjustable upwarp degree. The rigid structure frame comprises a plurality of central frames with a skidding support as well as a tail roller. The invention is an assembly equipment set specially developed for coal mine underworkings drifting equipment alpine bolter miner set, can realize mechanical continuous operation of driftage of drifting, rock bolting, material breaking and transporting after being matched with the alpine bolter miner and a main transporting device, and can greatly improve driftage efficiency and security, so that the alpine bolter miner can develop production capacity thereof.


BACKGROUND
Maculopapular drug eruptions (MPE) to antibiotics are associated with enhanced expression of Th1 cytokines like IFN gamma or Th2 cytokines like IL-5. Identifying the culprit drug usually involves re-challenge, which may not be forthcoming. Memory lymphocytes remain responsive to the culprit drug long after the reaction has resolved. Upon reactivation in-vitro, there is increased proliferation and expression of certain markers which provides us with an opportunity to predict the causal drug.

OBJECTIVE
The study aimed to assess drug-specific cytokine production (IL-5 and IFN-gamma) in peripheral blood mononuclear cell culture supernatants to predict the causal the antibiotic in maculopapular drug eruptions.

METHODS
Peripheral blood mononuclear cells of 20 patients who developed MPE to various antibiotics and 11 drug-matched healthy controls were incubated for five days with the respective drugs at two different concentrations. Cytokines secreted were measured in the supernatants at 6 hours, day 2 and day 5 using enzyme-linked immunosorbent assay (ELISA) for IL-5 and IFN-gamma.

RESULTS
Drug-specific IL-5 and IFN-gamma production could be demonstrated in 65% and 73.6% of the cases, respectively. Maximal secretion of IL-5 and IFN-gamma were observed on day 5 and day 2 of incubation, respectively. The cut-off Delta values, which are the difference in cytokine concentration of the drug-stimulated and unstimulated samples, were 4 pg/ml and 6 pg/ml for IL-5 and IFN-gamma, respectively.

CONCLUSION
The measurement of drug-specific secretion of IL-5 and IFN-gamma using ELISA is a valuable method for detecting antibiotic-induced maculopapular exanthema.


A rich class of network models associate each node with a low-dimensional latent coordinate that controls the propensity for connections to form. Models of this type are well established in the literature, where it is typical to assume that the underlying geometry is Euclidean. Recent work has explored the consequences of this choice and has motivated the study of models which rely on non-Euclidean latent geometries, with a primary focus on spherical and hyperbolic geometry. In this paper, we examine to what extent latent features can be inferred from the observable links in the network, considering network models which rely on spherical, hyperbolic and lattice geometries. For each geometry, we describe a latent network model, detail constraints on the latent coordinates which remove the well-known identifiability issues, and present schemes for Bayesian estimation. Thus, we develop a computational procedures to perform inference for network models in which the properties of the underlying geometry play a vital role. Furthermore, we access the validity of those models with real data applications.


The uniformity of phosphorus concentration produced by nuclear transmutation and the distribution of other elements such as gold have been studied to observe the possible influence of the neutron flux at a microscopic level in neutron irradiated silicon. Two techniques were used : i) electrochemical sectioning and ii) mechanical sectioning. Both methods show that the phosphorus concentration is uniform throughout. Gold, on the other hand, is concentrated at the surface.


Unlike the conventional transmission lines and waveguides, in which, as a rule, the wave propagates only in one region, in slow-wave structures (SWSs) with the electron beam (e-beam) the wave propagates or concentrates at least in three regions. Besides, in the most cases slow waves are represented by components of the E- and H-waves, each of them with different boundary conditions. This doubles the number of the boundary conditions, which achieves 16 for two regions SWSs plus 4 boundary conditions for the e-beam.


The utility model discloses a virtual reality glasses, including glasses body and bandeau, the glasses body includes the eyeshade, the optical enlargement eyepiece system that is connected with the eyeshade, but folding joint cover, a back lid that is used for holding display terminal's terminal to place the frame and place the frame with the terminal and be connected, but the material of folding joint cover is made for having pliable and tough elastic plastic, optical enlargement eyepiece system is equipped with eye illness lens installation department, the terminal is placed the frame and is equipped with the gesture response window corresponding with display terminal's gesture inductor position, the bandeau is including setting up the right side area at glasses body right -hand member, the setting is in the left side area and the last apical string of setting in glasses body upper end of glasses body left end, the utility model discloses be convenient for take in carry, wear adjust convenient, lightened virtual reality glasses to the constriction of head, can use gesture and button to carry out the patient that operation controls, order have an eye illness to virtual reality glasses's display terminal can to watch complete clear virtual reality picture like normal person's eyes.


Objective
To evaluate the relationship between autophagy and diabetes mellitus-caused influence on ischemic preconditioning(IP)-induced cardioprotection in rats.

Methods
Clean-grade healthy male Sprague-Dawley rats, aged 12 weeks, weighing 290-320 g, were used in this study.Diabetes mellitus was induced by high-fat and high-sucrose diet (lasting for 1 week) and intraperitoneal streptozotocin 50 mg/kg (for 2 consecutive days) and confirmed by fasting blood glucose level≥16.65 mmol/L (for 1 week). Thirty rats with diabetes mellitus, weighing 350-450 g, were divided into 3 groups (n=10 each) using a random number table method: sham operation group (DM-S group), myocardial ischemia-reperfusion (I/R) group (DM-IR group) and IP group (DM-IP group). Another 30 non-diabetic rats were selected and divided into 3 groups (n=10 each) using a random number table method: sham operation group (S group), myocardial I/R group (IR group) and IP group.Myocardial ischemia was induced by ligation of the anterior descending branch of left coronary artery for 30 min followed by 120 min reperfusion.IP was produced by 3 cycles of 5-min ischemia followed by 5-min reperfusion prior to establishment of myocardial I/R injury model in IP and DM-IP groups.Blood samples were collected from the internal jugular vein at the end of reperfusion for measuring serum concentrations of cardiac troponin I (cTnI) and creatine kinase-MB (CK-MB). The rats were then sacrificed and myocardial tissues were obtained for determination of myocardial infarct size and expression of microtubule-associated protein 1 light chain 3 Ⅱ (LC3 Ⅱ), Beclin-1, phosphatidyl-inositol 3-kinase (PI3K), protein kinase B (Akt), phosphorylated Akt (p-Akt) and mammalian target of rapamycin (mTOR) (by Western blot). p-Akt/Akt ratio was calculated.

Results
Compared with S group, the serum cTnI and CK-MB concentrations were significantly increased, the percentage of myocardial infarct size was increased, the expression of LC3Ⅱand Beclin-1 in myocardial tissues was up-regulated, the expression of PI3K and mTOR was down-regulated, and p-Akt/Akt ratio was decreased in IR group (P 0.05).

Conclusion
The mechanism by which diabetes mellitus abolishes IP-induced cardioprotection may be related to inhibiting activation of PI3K-Akt-mTOR signaling pathway and enhanced autophagy in rats.

Key words:
Autophagy; Diabetes mellitus; Ischemic preconditioning; Myocardial reperfusin injury


Based on analytical hierarchy process and fuzzy comprehensive evaluation,applying GIS as the data processing platform,a comprehensive evaluation model was established to judge ecological carrying capacity in Baotianman Nature Reserve in Funiu Mountain,Henan Province,China,which was seriously interfered by tourist activities.It was found out that the reserve was in the state of potential overload,ecological environment exhibited vulnerability,indicating that the ecosystem of vegetation landscape did not essentially deteriorated.However,some "quantitative" deterioration existed.


Proton exchange membranes based on polyacrylonitrile(PAN)/silica composites doped with heteropolyacids such as phosphotungstic acid(PWA) or silicotungstic acid(SiWA) were prepared by sol-gel method.The proton conductivity,water retention and chemical oxidation resistance of these composite membranes were investigated.The composite membranes can exhibit an anhydrous proton conductivity as high as 10~(-6) S·cm~(-1) at room temperature,and increases to 10~(-4) S·cm~(-1) order of magnitude at an intermediate temperature of 140 ℃.The water retention of the composite membranes at higher temperature can be improved by the addition of silica and heteropolyacids.Compared with pure PAN membranes,the chemical oxidation resistance of the composite membranes is improved significantly.


Method, and determining at least one valid network control function instances within the measurement interval, selecting measurement data of the next measurement interval with respect to at least one of the following features, the measurement data of the next measurement interval dependence to, and executing at least one of the following features. .FIELD 7