The uses of traditional plant extract in the treatment of various diseases have been flourished. The present study was aimed to evaluate the effect of Lepidium sativum aqueous extract on the fertility criteria in male mice. Forty-eight mice used in this experiment divided into four groups (12 mice each group). Group 1 (Control), group 2 treated with L. sativum aqueous extract for 2 weeks, group 3 treated with the sulpiride drug to conduct over weight and hyperprolactinemia for 6 weeks and finally group 4 treated with the sulpiride drug for 6 weeks and then with L. sativum aqueous extract for 2 weeks. The results show that the weight does not change over the first three weeks, but there is a significant increase in body weight at the fourth week, especially in the groups (3 and 4). The groups treated with the drug sulpiride showed body weight higher than that of the control group. The group treated with both, drug and LS was showed the higher level of LH, while the group which was treated with LS only showed the higher level of FSH. Prolactin showed its lowest level in the group treated only with LS extract when compared with treated groups. Testosterone showed the higher level in the group treated only with LS extract. The group treated with the drug sulpiride and have a high level of prolactin showed a decline in all the parameters related to infertility. This group had the lowest sperm count (53.33 ± 1.76) sperm/ml, motility (33.33 ± 3.33) % and viability (46.67 ± 1.67) %, in comparison to other groups. In general, there is a significant difference in all the parameters comparison with control group. The group treated with sulpiride drug and has high level of prolactin, showed a decline in all the parameters related with infertility. On the other hand, all the infertility parameters enhanced in the hyperprolactenimic animals which were treated with LS extract. In general there are significant differences in all the parameters comparison with control group. Histological sections for the testis in the group treated with LS only showed a look-like normal appearance of seminiferous tubule with presence of high number of sperms, while sections of hyperprolactinemic mice testis showed partial degeneration and damage of dispersed spermatogonia cells with still presence of sperms inside the lumen with certain morphological abnormality in the shape of the sperms. Sections of treated mice testis showed a look like normal shape and structure of seminiferous tubules with the presence of normal morphology shape sperms in the lumen. The findings of this study highlight the usefulness of using local and easily available plant products and constituents in treating or preventing diseases. The findings are encouraging and warrant further work on the aqueous extract of L. Sativum seeds and its effects


Visceral leishmaniasis (VL), a phlebotomine-borne neglected tropical disease, is caused by parasites of the Leishmania donovani complex. While L. donovani infection is restricted to the Indian subcontinent and East Africa, where transmission is anthroponotic, Leishmania infantum occurs in Europe, North Africa, and parts of Latin America, where it is zoonotic in nature with dogs as reservoir hosts. Though the incidence of VL caused by L. infantum has been on the decline, L. donovani continues to cause epidemics periodically. By and large, a small proportion of L. donovani infection manifests as clinical disease but majority of the infected individuals remain asymptomatic and contribute to the perpetuation of the VL transmission cycle via the sand fly vector. This is one of the major stumbling blocks to World Health Organization initiatives to eliminate this deadly disease by 2020. These parasites reside within the host macrophages and impair the immune system of the infected individual, which ultimately results in marked immunosuppression. In the absence of any safe and effective vector control measure, attempts have been made to design therapeutic vaccine(s) that can exclusively target infected macrophages. So far, two vaccines – a glycoprotein complex from L. donovani promastigote, fucose–mannose ligand with saponin, commercialized as Leishmune®, as well as a polyprotein vaccine formulation, Leish-111f + monophosphoryl lipid A plus squalene emulsion in combination with glucantime, have been successfully evaluated for their immunotherapeutic potential against canine VL. However, encouraging results obtained from several experimental trials so far against human VL are still to be translated clinically. This review provides an overview on the various strategies tried and tested for developing therapeutic vaccines against this dreaded disease.


Magnetism is a collective phenomenon. Hence, a local variation on the nanoscale of material properties, which act on the magnetic properties, affects the overall magnetism in an intriguing way. Of particular importance are the length scales on which a material property changes. These might be related to the exchange length, the domain wall width, a typical roughness correlation length, or a length scale introduced by patterning of the material. Here we report on the influence of two artificially created length scales: (i) ion erosion templates that serve as a source of a predefined surface morphology (ripple structure) and hence allow for the investigation of roughness phenomena. It is demonstrated that the ripple wave length can be easily tuned over a wide range (25–175 nm) by varying the primary ion erosion energy. The effect of this ripple morphology on the induced uniaxial magnetic anisotropy in soft magnetic Permalloy films is studied. Only below a ripple wavelength threshold (≈60 nm) is a significant induced magnetic anisotropy found. Above this threshold the corrugated Permalloy film acts as a flat film. This cross-over is discussed in the frame of dipolar interactions giving rise to the induced anisotropies. (ii) Ion implantation through a lithographically defined mask, which is used for a magnetic property patterning on various length scales. The resulting magnetic properties are neither present in non-implanted nor in homogeneously implanted films. Here new insight is gained by the comparison of different stripe patterning widths ranging from 1 to 10 μm. In addition, the appearance of more complicated magnetic domain structures, i.e. spin-flop domain configurations and head-on domain walls, during hard axis magnetization reversal is demonstrated. In both cases the magnetic properties, the magnetization reversal process as well as the magnetic domain configurations depend sensitively on the artificially introduced length scale.


This study was aimed to present a basic data to suggest the direction of making good use of leisure-time for high school taekwondo athletes by investigating the relationship between leisure constraints and satisfaction based on the types of leisure. This study was on the assumption that taekwondo athletes would improve on their performance. For this study, the data of 404 was collected from high school taekwondo athletes in Seoul and Kyeonggi area, and data was analyzed with SPSS 15.0 and AMOS 7.0 program for the descriptive, exploratory factor analysis, reliability analysis, ANOVA, and correlation analysis. The results of this study were as follows: First, leisure constraints was the most affected by recreational type of leisure activity, active type of leisure activity was located in the highest rank in the leisure satisfaction. Second, the influence of mediator was verified that the effect of leisure satisfaction according to leisure activity types comes from leisure constraints. In conclusion, coaches should need to encourage taekwondo athletes to active type of leisure activity in order to raise the leisure satisfaction.


Optimal productions of tannase by Aspergillus niger B0201 using uncooked material and solid-state fermentation with shallow trays were studied through single factor experiments in this paper.The results showed that the optimal fermentation conditions were as follows: seed age 30 h,inoculum 20%,gallnut content 30%,the ratio of solid to liquid 1.61,temperature 35℃(0 h~48 h),25℃(48 h~96 h) and 30℃(96 h~120 h),medium content 100 g and stirring every 24h during fermentation.Under these conditions,the enzyme activity reached 21.08 U.


The digital transformation of society is leading to the creation of a large number of distributed automated information systems in various areas of modern life. The need to meet security and reliability requirements prompts the creation of tools for their automated testing. Fuzzing within the security development lifecycle (SDL) is a strictly required tool for solving this problem. Tools for fuzzing binary-only applications are in demand too. These kind of fuzzing tools provide the search for critical defects in already functioning systems. It is especially acute when researching the security of proprietary systems operating using closed protocols. In the course of the research, it was found out that for fuzzing network applications in the absence of source codes, the use of universal fuzzers is complicated by many factors. These circumstances are pushing for the creation of an easy-to-use tool for network applications fuzzing. The paper discusses the features of fuzzing of this kind of programs and suggests possible solutions to the identified tasks.


The invention discloses a lighting device. The lighting device comprises a first slight light-emitting unit, a second slight light-emitting unit, a first voltage feeding point and a second voltage feeding point, wherein the first slight light-emitting unit comprises a first pair of diode micro-gains reversely connected in parallel, and the second slight light-emitting unit comprises a second pair of diode micro-grains reversely connected in parallel. By the lighting device, first loop selection and second loop selection can be provided, the first loop selection comprises the first voltage feeding point, the second voltage feeding point, the first slight light-emitting unit and the second slight light-emitting unit, and the first slight light-emitting unit and the second slight light-emitting unit are connected in series in the first loop selection; and the second loop selection comprises the first voltage feeding point and the first slight light-emitting unit and does not comprise the second voltage feeding point and the second slight light-emitting unit.


According to various surveys, the percentage of women editing Wikipedia barely reaches 10 percent.1, 2 The issue of gender distribution on Wikipedia was first brought to public attention by an article in the New York Times on January 2011. The article, titled "Define Gender Gap? Look Up Wikipedia's Contributor List,"3 started by highlighting how, in just ten years, the Wikipedia community accomplished some remarkable goals, such as reaching more than 3.5 million articles in English and starting an online encyclopedia in more than 250 languages. Yet Wikipedia failed to reach at least a minimal gender balance: according to the United Nations and Maastricht University 2010 reported survey, less than 13 percent of contributors were female. A more recent survey carried out in 2011 by the Wikimedia Foundation, the nonprofit organization that coordinates the various Wikipedia projects,4 reported even a steeper gender gap: women account for just 9 percent of editors. The importance of Wikipedia editors' diversity is relevant since Wikipedia is increasingly becoming one of the most accessed Web sources for information needs. Some 53 percent of American Internet users searched for information on Wikipedia as of May 2010; 88 percent of 2,318 university students used Wikipedia during a course-related research process, and finally, Wikipedia is the sixth most visited site on the entire Web.5 Thus, because so many people read the content of Wikipedia pages, it is important to become aware that these pages reflect the point of view of a predominantly male population. This issue has also been addressed by the Wikimedia Foundation, and in fact they have devoted attention to gender balance on Wikipedia as one of the key points of their five-year strategic plan of 2010: "Doubling the percentage of female editors to 25 percent by 2015."6


The history of IUCD insertion can sometime come into highlight only after imaging is done. Patient tends to forget about their IUCD.


Level of service predetermines consumer's tendency to acquire product. Redundancy of offers at market makes companies seek for additional competitive advantages to emphasize their product among the majority of similar ones. This is what comprises relevance of the work. Its goal implies target parameters of product service as an element of innovation activity of enterprise. In the modern context the service is the one of significant sources of income for equipment manufacturers. International competition provides the necessity of putting emphasis just on the service. This, in turn, stipulates the necessity of goal-oriented service management and, correspondingly, makes issues of revealing key indicators of service activity actual. Authors of the paper represent existing models of innovative product service, offer authors' goal-setting model for product service at enterprise, describe current limitations and conditions of applying the model. There are also requirement to production of enterprise for different service levels.


The design and performance of a circularly polarized microstrip patch antenna, for the application in Wireless Local Area Network (WLAN), are reported here. The antenna is a proximity coupled microstrip patch antenna where the radiating patch is loaded by a V-slot. This miniaturized microstrip antenna has wide bandwidth in the frequency band of WLAN and exhibits circularly polarized far field with very good axial ratio bandwidth. The simulated results using IE3D software are verified by measurement.


Chicago, Sept. 26, 1903. To the Editor: —InThe Journal, Sept. 26, 1903, appears an editorial under the above heading, which challenges some comment.... Hypnotism, as now understood by men who have had personal experience with it, is really synonymous with suggestion. The Charcot school is responsible for the term artificial hysterical state occasionally cropping up in medical literature. Charcot conducted his experiments with hypnotism on about a dozen or more hysterical patients which were demonstrated to the whole world in order to prove his theories. The peculiar method used and the frequency with which these patients were hypnotized contributed toward their becoming perfect automatons of unconscious suggestion. Hypnotism as practiced now is nothing else but suggestion administered during a state of greatest susceptibility to suggestion. I can not conceive how you can recommend suggestive therapeutics and condemn hypnosis when to successfully practice the first the second is often an


Rose Brister is Adjunct Professor of English at Stevenson University. She received a Ph.D. in English from the University of North Carolina at Greensboro. Her research explores the ways that postcolonial and Anglophone literatures of the late twentieth and twenty-first centuries imagine competing claims to place. Her work has appeared or is forthcoming in the journals College Literature, Signs: Journal of Women in Culture and Society, and South Asian Review.


Abstract : In a real gas, in the presence of a temperature gradient, the relative concentrations of the molecular clusters vary from point to point; this leads to a diffusion of the larger clusters towards the warm regions and of the smaller clusters and monomolecules towards the cold parts of the apparatus, where they respectively dissociate or recombine with the absorption or liberation of the heat of formation. The increase in the thermal conductivity of the gas resulting from this circulation of the heat of formation of the clusters can be evaluated with reasonable accuracy at low pressures when only simple and double molecules need to be taken into account. This effect is negligible at high temperatures (above the Boyle point), where the variation of thermal conductivity with pressure can be represented to a high degree of accuracy by Enskoyg's theory; it increases with decreasing temperature, and becomes approximately equal to Enskog's effect in the neighborhood of the critical temperature; it is evaluated that in the case of argon the increase is of the order of 6% per atm. at the boiling point.


Secondary ion mass spectrometry is employed to investigate diffusion of H2 implanted in hydrothermally grown single crystal ZnO. Diffusion profiles have been studied after 30 min isochronal heat treatments from 100 to 400 °C and evaluated using three different models: the infinite source model, a solid solubility limited model, and a trap limited model. Only the latter one reproduces closely the measured values. From this model an activation energy Ea=0.85 eV is extracted, and it is speculated that trapping may be a source of the discrepancies between the reported values of Ea in the literature.


Background. The article presents the results of research into the concept of existential guilt in foreign psychology. Currently, the problem of experiencing existential guilt occupies one of the central places in psychological research. This is due to the fact that in extreme life situations (war, pandemic, economic and social danger, etc.), a person's experience of a sense of guilt, and especially existential guilt, increases sharply. The purpose of the study: to reveal the meaning of the concept of guilt and its types, the peculiarities of the individual's experience of existential guilt. Methods. To solve the tasks, the work used methods of theoretical and empirical research: a) theoretical methods analysis, classification, types, generalization made it possible to scientifically and theoretically substantiate the data we received; b) empirical methods - diagnosis of self-actualization of students, content analysis of the experience of guilt in students with a high and low level of self-actualization of the personality. Results. Analyzed concepts: guilt, fear, anxiety, existential guilt, shame. A comparison of the emotions of shame and guilt shows that the feeling of shame often activates defense mechanisms, leads to distancing from the situation, while the feeling of guilt causes constructive responses and a desire to correct the situation; guilt is positively related to empathy, and shame is inversely related to it; finally, the feeling of shame can lead to psychological distress - depression, anxiety, obsessive states, low self-esteem, eating disorders, etc., while with regard to the feeling of guilt, similar connections have not been recorded Conclusion. The general conclusion is that the feeling of guilt is positive from the point of view that it not only keeps a person within a moral framework, but also motivates to act correctly and strive to correct the situation.


The age of globular clusters inferred from observations depends sensitively on assumptions such as the initial helium abundance and the mass loss rate. A high helium abundance (e.g., $Y\approx$0.28), as well as an inclusion of helium diffusion and oxygen-enhancement in stellar models, can lower the current age estimate for metal-poor globular clusters from 14$\pm 1.5$ Gyr to about 11$\pm 1$ Gyr, significantly relaxing the constraints on the Hubble constant, allowing values as high as 60km/sec/Mpc for a universe with the critical density and 90km/sec/Mpc for a baryon-only universe. The uncertainties of a high helium abundance and an instability strip induced mass loss near the turn-off in globular clusters are discussed. Ages lower than 10 Gyr are not possible even with the operation of both of these mechanisms unless the initial helium abundance in globular clusters is $>0.28$, which can hardly be accomodated by indirect inferences of helium abundances in globular clusters.


The significance of the reign of Alexander III as a turning point in the history of Russian Jewry is beyond dispute. This reign witnessed a sharp deterioration in the Jews' economic, social, and political condition. Jewish hopes for emancipation from the prevailing discriminatory legislation were dashed. Instead of emancipation, the Jews were presented with new restrictions, on their residence rights, educational opportunities, economic and professional pursuits, and participation in the institutions of local government. Faced with starvation, many thousands of Jews chose to leave the Russian Empire. Others chose to convert to Christianity in order to throw off the yoke of persecution. Moving in the opposite direction, many Jewish intellectuals who had previously believed in the beneficial results to be achieved by assimilation began to question this assumption. Some began to turn to Zionism. Others turned to active Jewish self-defense.


Some deem the Bolsa Família program (BF) in Brazil to be a quintessentially clientelistic tool, thought to have produced colossal sociodemographic transformations in the base of support of President Luiz Inácio Lula da Silva, particularly in the 2006 election. An earlier article (Bohn 2011) maintained that significant changes in Lula's electoral base took place prior to his reelection; other social policies, such as the Benefício de Prestação Continuada, contributed significantly to the changes in Lula's camp; and, most important, that the link between the receipt of social benefits and vote is less straightforward than those who view Bolsa Família as a clientelistic program assume it to be. This work addresses some of the criticisms that the article received and reinforces the need for further research that uses individual-based data to disentangle the complexity of the electoral behavior of the poor in highly unequal societies.


Listening is one of the most important parts of college English teaching.Due to the lack of necessary language environment,students are inclined to meet with various barriers in their learning.From the perspective of bar- tiers in the listening comprehension process,some feasible strategies for improving the listening ability are concluded as follows:to provide abundant language materials;to focus on the training of listening skills;to lay emphasis on the com- bination of"listening,speaking,reading,writing,and viewing";and to adopt the multimedia assisted training.


The government has conducted the program of systematic and complete land registration (PTSL) in order to have a legal certainty guarantee and protection of human rights in owning land fairly and evenly, as well as to encourage the state economic growth generally and the community economy in Indonesia. The registration system is regulated by the Ministry of Agrarian and Spatial/ the head of BPN No.12 in the Year 2017 regarding the acceleration of systematic and complete land registration. The study examines the implementation of the PTSL program in Surabaya. This is a literature study that describes and analyzes by using policy implementation theory in George C. Edward III. The variables are communication, resources, disposition, and bureaucratic structure. The results explain that Surabaya has conducted a PTSL program which is begun from 2017 to recent years. The program continues to be carried out, so that the implementation of PTSL program in Surabaya has been done properly. The supporting factors in PTSL implementation re communication, i.e. the definite program, and bureaucratic structure in Standard Operating Procedure (SOP). Whereas, the inhibiting factors are the human resources, for example, the staff, budget, and the information. In addition, human resource is the most inhibiting factor in the process of PTSL implementation in Surabaya. The study also suggests that it is important to have management information system in land registration for supporting PTSL implementation.


In recent years, humanoid robot soccer robots have shown increasingly robust and fast locomotion, making perception, world modeling and behavior control important. In this paper, we present the world modeling approach of the Darmstadt Dribblers humanoid robot team, which won the competitions in the RoboCup Humanoid KidSize League in 2009 and 2010. The paper focuses on modeling observation uncertainties originating from different contributing factors centrally in one module. This allows different state estimators to use this data in a consistent way, independently of the specific state estimation approach used.


In the work by Cannon, amolecular mechanics model was developed for sulfate in waterbased on Hartree-Fock (HF/6-31+G*) geometrical and fourth-order Moller-Plesset (MP4) energetic results for the monohy-drate. Our work will verify these calculations and extend them,both in the optimization and the frequency calculation up toMP2/6-31+G* levels and by extending the cluster size tocontain up to six waters.2. Materials and MethodsCalculations were performed using Gaussian 92,


Chemokine (C-X-C motif) receptor 4 (CXCR4) has been reported as a poor prognostic biomarker in human breast cancers, and has been suggested as a promising therapeutic target of breast cancer treatment. The present study aims to investigate the delivery efficiency of siRNA by chitosan into breast cancer cells, and then to examine the regulatory role by chitosan nanoparticle-delivered siRNA on CXCR4 expression and on the chemosensitivity of breast cancer cells. Our results demonstrated that the siRNA could be capsuled by chitosan into nanoparticles with a diameter of 80–110 nm, and with a zeta potential of 20–50 mV. The chitosan nanoparticle delivered siRNA efficiently into breast cancer MCF-7 cells significantly reduced the expression of CXCR4 in both mRNA and protein levels. Moreover, the reduced CXCR4 by chitosan nanoparticle-delivered siRNA was associated with increased sensitivity of breast cancer cells to cisplatin. Reduced growth and increased apoptosis of MCF-7 cells were observed in the CXCR4 siRNA group than in the control siRNA group. Taken together, our results present the treatment potential of chitosan nanoparticle-delivered siRNA targeting CXCR4 in breast cancers.


The World Bank has announced a dramatic shift in water policy that will nearly quadruple its spending in this area while it shifts the emphasis toward sustainable development. Instead of financing project-oriented investments in irrigation, water supply, sanitation and hydropower, the Bank will lend for environmentally sustainable, river-basin-wide water resource management. Privatization and decentralization are other aspects of the new policy. The implications of water policy are particularly important in the Middle East, where in the long run peace may depend on the way in which available water is allocated; proposed projects in the region are discussed, as is the need for improved data on surface and groundwater.


This chapter classifies the risk and fundamental elements necessary to manage it. It presents the individual stages of the procedure and standards of conduct in risk management. In accordance with the EU accession agreement, Poland has developed and implemented a system of financial management and control standards in public finance sector units. This chapter presents the risk assessment tools that can be customized to the needs of a specific organization, including public sector entities. Information about how to manage risk in each EU country are made available because of the desire to show the stability and proper monitoring of the risks in order to fulfil the given tasks. This affects the perception of stability in the country, which has a direct impact on the economic effects.


Various investigators have presented evidence to show that the hypophysis plays an important role in carbohydrate metabolism. Houssay (1) and his coworkers were the first to show that extracts of the anterior lobe of the hypophysis, when injected into normal dogs, produce hyperglycemia, glycosuria and ketonuria (2). Furthermore, these extracts, when given in high doses, inhibit dextrose utilization and a diabetic condition is produced. The ablation of the pituitary leads to hypersensitivity to insulin, hypoglycemia, convulsions during fasting, and an increase of dextrose tolerance (3, 4). All these findings have received adequate confirmation. In depancreatized dogs the removal of the hypophysis restores carbohydrate metabolism to an approximately normal condition but on the other hand renders the animal hypersensitive to insulin (5, 6). The injection of the anterior lobe extracts to the depancreatizedhypophysectomized animal causes a reappearance of the symptoms of diabetes. This subject has been reviewe...


"KNOW, MY BROTHER, that you will find great differences in interpretation of the Song of Songs. In truth they differ because the Song of Songs resembles locks to which the keys have been lost." So wrote Rabbi Saadia Gaon al-Fayyumi in the tenth century, in words that still ring true. Few texts in the Hebrew canon have been so impervious to our critical inquiries as the Song. Scholars versed in this interpretive quagmire know the score. The text of the Song is perennially enticing, as it constantly invites the reader into a narrative-like context that never quite takes shape. Is the Song a drama performed by two or even three characters, or is its narrative flavor an illusion played on us by a collection of disparate love songs? Is the text about human love, about divine love, or is it perhaps a political allegory? For answers to these questions, modern scholars have frequently turned to comparative literature from the ancient Near East, but this has often served as a two-edged hermeneutical sword. Although comparative considerations have eman cipated us from rigid allegories, which preclude an appreciation of the Song's vivid portrayal of human love and sexuality, the comparative evidence has at the same time introduced a degree of generic confusion. On the basis of the ancient Near Eastern context, the book has been construed as a sacred marriage text (like the Inanna/Dumuzi texts), as a royal love song (like the Sumerian royal love songs),


The Bluest Eye written by African American writer Toni Morrison narrates a tragic story about a black girl who longs for a pair of blue eyes owned exclusively by white people.Strongly influenced by white dominated culture,many other black women are also lost in the myth of white beauty.However,in addition to the description of this negative impact,Morrison,in her novel,also explores effective approaches to demystify the myth of white beauty and maintain the real-self of the black people through the voice of a rebellious narrator.


Bacillus aciditolerans YN-1T was isolated from Jietou town, Yunnan Province, China and exhibited various lignocellulolytic activities which had the ability to decompose straw. In this work, we found that strain YN-1T was capable of degrading
 different types of straw and showed the highest efficiency to the degrading of corn straw. We also draw the draft genome sequence of strain YN-1T , which composed of 4,633,983 bp chromosome. Results showed that Bacillus aciditolerans YN-1T contains
 3455 protein coding sequences and 249 were associated with the carbohydrate metabolism. Meanwhile, CAZymes analysis also showed that strain YN-1T contains 60 coding genes of glycoside hydrolase (GH) family, implying that Bacillus aciditolerans YN-1T
 has broad applications in the degradation of straw.


Temporal arteritis, or giant cell arteritis, is an important disease erroneously considered to be rare because of lack of awareness and recognition of the disease by physicians. According to the authors, their primary aim is to increase physicians' awareness of temporal arteritis and to help them recognize and treat the dreaded disease. This monograph is essentially a review of most of the literature on systemic manifestations of temporal arteritis, with occasional reference to the authors' experiences with the disease. After a historical review, various systemic clinical manifestations of temporal arteritis, eg, myalgia, malaise, anorexia, weight loss, fever, anemia, malignancy-like presentation, cranial and neurological manifestations, aortic arch syndrome, and cardiac disorders are discussed. There is a detailed account of the clinical picture of polymyalgia rheumatica. Whether polymyalgia rheumatica is always a manifestation of temporal arteritis or not is discussed at length; the conclusion is that the question cannot yet be answered


ABSTRACT The aim of this research is to utilize a novel approach called geographically weighted shift-share (GWSSA) analysis to estimate the degree and manner to which recent destination redevelopments have played a role in changing the characteristics of the nearby population and housing in Detroit between 1990 and 2010. The main benefit of geographically weighted shift-share analysis is that this technique isolates the local changes due to such projects while simultaneously controlling for the amount of the change expected for unrelated factors (e.g., the exodus of people leaving Detroit due to its overall negative reputation). Results suggest that such destination redevelopments in Detroit seem to be connected to a number of surprising positive local impacts during this period related to total population, 18-to-29-year-olds, non-Hispanic whites, employed civilians, unemployed civilians, households earning between $50,000 and $100,000 in annual income, total housing units, occupied housing units and vacant housing units.


Distortion allocation varying with wavelength in lossy compression of hyperspectral imagery is investigated, with the aim of minimizing the spectral distortion between original and decompressed data. The absolute angular error, or spectral angle mapper (SAM), is used to quantify spectral distortion, while radiometric distortions are measured by maximum absolute deviation (MAD) for near-lossless methods, for example, differential pulse code modulation (DPCM), or mean-squared error (MSE) for lossy methods, for example, spectral decorrelation followed by JPEG 2000. Two strategies of interband distortion allocation are compared: given a target average bit rate, distortion may be set to be constant with wavelength. Otherwise, it may be allocated proportionally to the noise level of each band, according to the virtually lossless protocol. Comparisons with the uncompressed originals show that the average SAM of radiance spectra is minimized by constant distortion allocation to radiance data. However, variable distortion allocation according to the virtually lossless protocol yields significantly lower SAM in case of reflectance spectra obtained from compressed radiance data, if compared with the constant distortion allocation at the same compression ratio.


The control of finite automata under modeling assumptions and specifications represented by Rabin acceptance conditions is considered. The controllability subset of an automaton-the set of states from which it can be controlled to the satisfaction of its specification-is characterized as a fixpoint of an operator on state subsets.<<ETX>>


The utility model discloses a hydraulic clutch soft-start device with a speed reducer, which is provided with a box body. A driving gear is arranged on a driving shaft of a coupler in the box body; a driven gear is arranged on a driven shaft of the coupler; a driven gear is arranged on a driving shaft of a clutch; a driven gear is arranged on a driven shaft of the clutch; the center distances of the two gear trains are equal, but the transmission ratio is not equal; a driving friction disc and a driven friction disc can axially slide under the action of a piston; a control oil circuit is arranged in the driving shaft of the clutch; and a lubricating oil circuit is arranged in the driven shaft of the clutch. The utility model enables the clutch, the coupler and the speed reducer to be integrated into a whole, so that the hydraulic clutch soft-start device has the advantages of high transmission efficiency, compact structure and less calorific power, can provide the smooth and impact-free starting torque and also can realize the overload protection and power balance.


Based on "Accounting Standard for Business Enterprise-Inventories",the purchasing agent's allowances for a business trip and expenses of purchasing organ,and expenses on goods in storage in initial stage are analyzed from theory and practice.In the end,new viewpoints are put forth.


i Purpose of the Assessment System 2 Conceptualizing Construct Validity for State Testing 3 Overview: Two reconstructions 3 Purpose of This Study 4


Objective To explore the effects of the triple drug therapy in treatment of intractable chronic cough. Methods One hundred and twenty cases of intractable chronic cough were chosen as study subjects and were divded into two groups( n = 60,each). The treatment group was treated with the triple drug therapy of chlorpheniramine,aminophylline,lidocaine,while the control group was treated with the conventional therapy. The two groups were compared for the clinical effect,the treatment time,psychological status and quality of life. Results The total efficiency rate of the treatment group was 96. 67%,higher than 71. 67% of the control group( P 0. 01). Both the scores of quality of life and normal psychological status rate of the treatment group were higher than those of the control group( P 0. 01). Conclusion The triple drug therapy in treatment of intractable chronic cough is effective and of clinical value.


The utility model discloses a liftable table for children. The liftable table comprises a support, a face plate and a bookshelf. The face plate and the bookshelf are mounted on the support, the support comprises a support frame and a base connected through a lifting column, table legs are arranged on the base, a leg pad is arranged on each table leg, the face plate is fixed on the support frame through telescopic dampers and a support connecting rod which are arranged on the support frame, and a retaining plate is further arranged on the face plate. Overall height of the table and inclination of the tabletop can be adjusted as required so as to adapt to the characteristic of fast growth of children, myopia and hunchback of children due to inappropriate desktop height and inclination are prevented, and comfortableness is high.


Notion of effective size of support (Ess) of a random variable is introduced. A small set of natural requirements that a measure of Ess should satisfy is presented. The measure with prescribed properties is in a direct (exp-) relationship to the family of Renyi's $\alpha$-entropies. Question of selecting the value of $\alpha$ most appropriate for the purpose of measuring Ess is briefly addressed.


www.unclosuk.org website developed to support National Oceanography Centre impact review, where UNCLOS activities were highly rated, and to provide up to date information relating to activities related to Law of the Sea.


This year marks the final year for the present editorial team. The four editors were chosen in part for their individual expertise in areas of global governance. For four years, as a matter of policy, the editors have refrained from submitting any of their own articles to the journal. In this final year, they have decided to write one Global Forum essay each as a way of saying farewell. This following is the first such essay by Ramesh Thakur.


FIELD: physics. SUBSTANCE: invention enables to determine the measure of concordance of wave signals in the frequency domain, involving construction, in the frequency domain, of at least one amplitude non-conformity functional and a cross-phase functional between entries. Parameters of the source and/or parameters of the model are then estimated from the found parameters with subsequent display thereof. EFFECT: high accuracy of probing data. 31 cl, 12 dwg


Many have criticized the centralized and unaccountable governance of prominent online social platforms, leading to renewed interest in platform governance that incorporates multiple centers of power. Decentralization of power can arise horizontally, through parallel communities, each with local administration, and vertically, through multiple hierarchies of overlapping jurisdiction. Drawing from literature on federalism and polycentricity in analogous offline institutions, we scrutinize the landscape of existing platforms through the lens of multi-level governance. Our analysis describes how online platforms incorporate varying forms and degrees of decentralized governance. In particular, we propose a framework that characterizes the general design space and the various ways that middle levels of governance vary in how they can interact with a centralized governance system above and end users below. This focus provides a starting point for new lines of inquiry between platform- and community-governance scholarship. By engaging themes of decentralization, hierarchy, power, and responsibility, while discussing concrete examples, we connect designers and theorists of online spaces.


The present invention provides a water stream is removed from one or more contaminants, comprising: one or more hydraulic binders and one or more promoters are added to the water stream, and from the separating the contaminant stream. The method may be used to remove arsenic-based, based on selenium, cadmium-based, zinc-based, mercury-based, iron-based, chromium-based and / or phosphate-based contaminants.


Polyamide 1010(PA1010)/nano-ZrO2 composite coating was prepared by flame sprayed.The processes of non-isothermal crystallization,the melt behavior of PA1010/nano-ZrO2 composite coatings were investigated by differential scanning calorimeter(DSC).The experimental results show that the crystallization temperature of PA1010/nano-ZrO2 composite coating increases due to the heterogeneous nucleation of nano-ZrO2 particles compared with pure PA1010 coating.A phenomenon of dual melting peaks appears during the melting process of pure PA1010 and PA1010/nano-ZrO2 composite coating.And the low melt peak temperature of the PA1010/nano-ZrO2 composite coating increases obviously as a result of the addition of nano-ZrO2 particles.Meanwhile,nano-ZrO2 particles act as a nucleation agents in the PA1010 matrix.


The Article focus mainly on the constitutional provision for women to get representation in Panchayat Raj Institutions. The 73 rd amendment to the constitution provides reservation for women which opens up the avenues to participate in preparing action plan, collection of revenue, allocation of resources, identification of beneficiaries at village level. These representatives have a "big say'' in the decision – making process. The Researcher has the primary objective of examining the aspects live; a) to see whether reservation for women in Panchayat Raj Institutions have enabled them to realize their potential as decision-makers. C) To understand to what extent women members participate in the process of decision-making. An empirical study was conducted in shivamogga District of Karnataka. The study covered one Zilla Panchayat, three Taluk Panchayat Samithies and 15 Grama Panchayats. Few women members were more dynamic in carrying out their roles and responsibilities. The important causes for representation being only nominal are: lack of education, patriarchal society, absence of courage and boldness, prevalence of shyness and inhibition, familial responsibilities etc. As a result women members have not completely succeeded in taking proactive participation in the administrative and developmental affairs of PRIs.


Background Introgression of the insect bacterium Wolbachia into Aedes aegypti mosquito populations been shown in randomised and non-randomised trials to reduce the incidence of dengue in treated communities, however evidence for the real-world effectiveness of large-scale Wolbachia mosquito deployments for arboviral disease control in endemic settings is still limited and no effectiveness studies have been conducted for chikungunya virus. A large Wolbachia (wMel strain) program was implemented in 2017 in Rio de Janeiro, Brazil. Here we assess the impact of the release program on dengue and chikungunya incidence. Methods and findings The program released 67 million wMel infected mosquitoes across 28,489 release locations over a 86.8km2 area in Rio de Janeiro between August 2017 and the end of 2019. Following releases, mosquitoes were trapped and the presence of wMel determined. To assess the impact of the release program on dengue and chikungunya incidence, we used spatiotemporally explicit models applied to geocoded dengue (N=194,330) and chikungunya cases (N=58,364) from 2010 (2016 for chikungunya) to 2019 from across the city. On average, 32% of mosquitoes collected from the release zones between 1 and 29 months after releases were positive for wMel. Reduced wMel introgression occurred in locations and seasonal periods when dengue and chikungunya cases were historically high. Despite incomplete introgression, we found that the releases were associated with a 38% (95%CI: 32-44%) reduction in dengue incidence and a 10% (95%CI: 4-16%) reduction in chikungunya incidence. Conclusions Stable establishment of wMel in this diverse, urban setting appears more complicated than has been observed elsewhere. However, even intermediate levels of wMel appear to reduce the incidence of two different arboviruses.


Photosystem II particles having an oxygen evolution activity as high as 300,ulnol mg-1 chlorophyll hr -1 were prepared from spinach chloroplasts using Triton X-IOO. The oxygen evolution system in these particles was stable; 70% of the original activity remained after storage of the particles at O°C for 7 days. When the particles were treated at pH 9.3, the oxygen evolution was specifically inactivated and three polypeptides having apparent molecular weights of 32,000, 24,000 and 15,000 were simultaneously released. This observation suggests that these polypeptides are associated with the oxygen evolution system of photosynthesis.


Some regular problems of natrium reagent used in spectrophotometry were discussed.The pH value was controlled to improve natrium reagent to get better complex solution.


ABS TRACT Ob jec ti ve: Re sin-mo di fi ed glass io no mer ce ments we re de ve lo ped by ad ding re sin to con ven ti o nal glass io no mer ce ments to im pro ve its physi cal and mec ha ni cal pro per ti es. Ho we ver this al so pro du ces ne ga ti ve pro per ti es such as po or bi o com pa ti bi lity. The po ten ti ally cyto to xic effects of re sin ce ments are pri ma rily du e to the 2-hydrox yethyl met hacr yla te con tent. The pur po se of this study was to de ter mi ne and com pa re the cyto to xi city of thre e dif fe rent re sin-mo di fi ed glass io no mer ce ments. Ma te ri al and Met hods: Thre e dif fe rent re sin-mo di fi ed glass io no mer ce ments; Ad van ce (Dentsply-Ca ulk, Mil ford, USA), Vit re mer (3M Den tal Pro ducts, St. Pa ul, USA), and Protec-CEM (Vi va dent Ets., Scha an, Li ech tens te in) we re used in this study. Spe ci mens of each type we re pre pa red, each with 10 mm. di a me ter and 1mm. depth. The se spe ci mens we re sto red in de i o ni zed wa ter for 10 mi nu tes, 1 ho ur, 24 ho urs and 7 days. Elu a tes we re col lec ted and se ri al di lu ti ons of the ori gi nal (un di lu ted) elu a tes (1:2, 1:4, 1:8, 1:16) pre pa red. So lu ti ons we re pas sed thro ugh 0.22 μm (Mil li po re) ste ri le fil ters. Cyto to xi city le vels we re de ter mi ned using the MTT met hod on L929 fib rob las tic cell cul tu res in 96 well pla tes. Re sults: Eva lu a ti on of the da ta with the Krus kal-Wal lis test re ve a led sig ni fi cant dif fe ren ces bet we en the ma te ri al gro ups and di lu ti on sub gro ups we re im por tant (p< 0.05). Vit re mer (3M) was the most cyto to xic for all fo ur de i o ni zed wa ter sto ra ge ti mes. Elu a tes of Ad van ce (Dentsply-Ca ulk) sho wed lo wer cyto to xic res pon se than elu a tes of Pro tec-CEM (Vi va dent Ets) from 10 mi nu tes to 1 ho ur, (p< 0.05). Conc lu si on: Wit hin the li mi ta ti ons of this inves ti ga ti on, elu a tes from thre e re sin-mo di fi ed glass io no mer ce ments (Ad van ce, Vit re mer, and Protec-CEM) we re fo und to be cyto to xic to L-929 cell cul tu res.


Particle swarm optimization (PSO) is a population-based stochastic optimization technique, inspired by the social behavior of birds (flocking) or fish (schooling), which is applied to various problems in the optimization of nonlinear systems. The inertia weights approach (IWA) and the constriction factor approach (CFA) are improved methods in PSO. The IWA searches the problem space globally in the early steps, and finally searches locally near the optimal solution. CFA is a method that introduces a new parameter into velocity update equation.

This paper proposes a combination of IWA and CFA (the Inertia Weights Constriction Factor Approach: IWCFA), and PSOrank, whose objective is the ranking of individuals in the population. These two proposed methods are applied to function optimizations and to the portfolio selection problem, which is a typical mathematical problem in securities finance. The results show that the original PSO finds better solutions than the GA, and the proposed method finds better solutions than the original PSO. © 2006 Wiley Periodicals, Inc. Electron Comm Jpn Pt 3, 90(3): 13–25, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecjc.20263


Production from the Schoonebeek heavy oil steam flood in northeast Netherlands was historically curtailed because of limits on H2S and water production. The interdependence of various permit and facility constraints makes production optimisation for Schoonebeek extremely challenging. So much so, that the conventional IPSM approach does not apply. To understand the field's production potential and to reach it, the team developed a novel Production System Optimisation (PSO) workflow using techniques from machine learning and operations research. In this paper we explain the details of this PSO workflow, the mathematics behind it, and share our results and learnings. The algorithm runs in 5 minutes and is used in daily optimisation. The application of this new workflow in combination with the successful deployment of a novel H2S scavenger, resulted in a Schoonebeek production uplift of 50%.


This paper examines how pupils with learning difficulties (LDs) used smartphones as supportive learning tools in an inclusive science class and how the usage developed over a two-year period. The case study was conducted in a Finnish primary school, where nine LD pupils' smartphone usage was followed in three science learning practices that supported LDs. The data consisted of repeated smartphone questionnaires, interviews, learning outcomes, and teachers' memoranda. The content and co-occurrence network analysis revealed that the smartphone usage varied in different practices, and its benefits developed gradually during the research period. Research highlights that teachers' and pupils' engagement with a dedicated, collaborative, and long-lasting process of smartphone usage in teaching and learning enables the achievement of change.


An asymmetric least squares estimation method has been employed to estimate linear models for percentile regression. An asymmetric maximum likelihood estimation (AMLE) has been developed for the estimation of Poisson percentile linear models. In this study, we propose generalized nonlinear percentile regression using the AMLE, and the use of the parametric bootstrap method to obtain confidence intervals for the estimates of parameters of interest and smoothing functions of estimates. We consider three conditional distributions of response variables given covariates such as normal, exponential, and Poisson for three mean functions with one linear and two nonlinear models in the simulation studies. The proposed method provides reasonable estimates and confidence interval estimates of parameters, and comparable Monte Carlo asymptotic performance along with the sample size and quantiles. We illustrate applications of the proposed method using real-life data from chemical and radiation epidemiological studies.


The Tamil writer P. Sivakami's sequential novels The Grip of Change (Pazhaiyana Kalithalum, 1989) and Gowri: Author's Notes (Gowri: Aasiriyar Kurippu, 1999) were written in the wake of the Bodi caste riots in Tamil Nadu between Pallars (a Dalit caste group) and Thevars. Dalits mobilised themselves around a Dalit leader when she was raped and killed by upper caste landlords for demanding higher wages. At a protest meeting, a Dalit political leader is reported to have said, "What would happen if all Dalit men were to marry upper caste women?" This led to a violent backlash resulting in the loss of Dalit lives and property. The reasons for raping the Dalit leader lay in suppressing a Dalit woman who was overstepping her subordinate status by publicly demanding higher wages. Thus caste functioned in markedly gendered ways in public spaces.
As a response to this event, Sivakami's novels focused on the body of the Dalit woman as a fictional and rhetorical figure for the fraught relationship between caste, gender and sexuality. The novel centers on the exploited and supposedly violable body of the Dalit woman, which is inscribed with inter-caste struggles for power even as it is constituted as a site of resistance. Over the course of the narratives, it becomes impossible to articulate caste and gender and sexuality at once. Caste turns out to be the overarching structure that regulates gender and sexuality primarily through the body of the (Dalit) woman. There is no space in this structure to articulate questions of sexual violence, that are clearly elided by caste violence, which subordinates the Dalit woman to the male interests of the Dalit community. The second novel is the author's reflection on the possibility of re-imagining the inter-sectionalities between caste, gender and sexuality.


The invention discloses a terminal capable of automatically recognizing a headset microphone and karaoke devices, and a recognition method thereof. The terminal comprises a detection module, a terminal MIC input module, a speaker, an audio processing module, and a processing unit. When the detection module detects plugging of an external device, a detection signal is output to the processing unit; the processing unit judges whether the plugged device is the headset or a karaoke device according to the level of the detection signal; when no device is plugged, the audio processing module controls an audio signal as input of the terminal MIC input module, and the audio signal is output by a speaker; when the karaoke device is plugged, the audio signal is switched to karaoke input and is output by the speaker; when the headset is plugged, the audio processing module judges whether the headset is provided with a microphone or not; if yes, the audio signal is switched to be input by the headset microphone and output by the headset; if not, the audio signal is controlled to be input by terminal MIC and output by the microphone. Therefore, the functions of the headset, the headset microphone and karaoke are achieved through a headset socket.


Thai Sign language is a sign language used in Thailand to communicate within the group of people with hearing losses or between ordinary people and people with hearing losses. For a given handshape, it is detected by a camera/webcam. 21 landmarks of a detected hand are inferred as a 3-tuple by MediaPipe. Some of angles between these landmarks are computed using Python programming. The angle set is compared with the training set and classified as a word by K-Nearest Neighbors algorithm. The dataset of Thai sign language used in this research is limited to the vocabularies that can be interpreted by one movement of handshape only. The accuracy of the interpretation in this research is about 84%.


A kind of polyurethane membrane with thermal sensitivity and pH response was successfully prepared by using thermal sensitive polyurethane(TSPU) material as the matrix membrane and through the surface graft modification technology to induce and graft functional group(acrylic acid) of pH response on the surface of matrix membrane.The IR analysis shows that the characteristic absorption peaks of carboxyl appear on the spectrum of the graft membrane,so that acrylic acid is successfully grafted on the TSPU membrane.The graft membrane morphology was observed by SEM.The results show that there is obvious existence of the poly-acrylic acid graft copolymer on the surface of the TSPU membrane.DSC analysis shows that surface graft modification has a little influence on the microphase-separated structure of the TSPU membrane and crystallization properties of soft segment.When the grafting time was controlled between 15min to 20min,and the temperature increased from 45℃ to 55℃,the water permeation flux of graft membrane changed markedly.On the other hand,when the pH changed from 4 to 5,the water permeation flux of graft membrane also changed remarkably.Therefore,the intelligent membrane materials with better thermal sensitivity and pH response can be successfully prepared by suface graft technology modifying TSPU membrane.


Last week, a three-judge panel on the U.S. Court of Appeals for the Fifth Circuit in New Orleans unanimously upheld Texas physician and microbiologist Thomas Butler9s conviction and 2-year prison sentence for illegally shipping bacteria to Tanzania and defrauding his former employer.


To set up a new method for rapid screening of recombinant clone.By taking the sequences from the plasmid vector and sequences from the inserted gene as the primer pairs,a method has been constructed with 5% Triton X-100 lysis buffer and PCR for scalping and identifying positive recombination plasmids conveniently and fast.The positive clone and orientation of DNA insertion were conveniently determined and the results were in good accordance with those by traditional restriction enzyme methods.This method could screen recombinant clone rapidly,while identifying the orientation and length of the inserted sequence.


Introduction The purpose of this literature synthesis is to highlight some of the challenges faced by internationally educated nurses with English as a second language when integrating into the Canadian health-care environment and to suggest educational strategies that work to support these diverse learners to acculturate and fill gaps. Methodology: A search of Google Scholar, PubMed, CINAHL, MEDLINE, and ProQuest Nursing and Allied Health databases, as well as reference lists, conference presentations, and gray literature produced pertinent research studies and commentary published between 2008 and 2018. Results Common themes in the literature include challenges relating to communication, cultural competence, and critical thinking. Discussion Some strategies that should be included in bridging education programs to address these challenges are evolving case studies, simulation and role-play, and practice performing multiple-choice tests. Research is needed examining the effectiveness of experiential techniques in preparing internationally educated nurses for nursing in the Canadian context.


Sexual violence in the context of the COVID-19 pandemic has greatly increased. This is certainly very threatening the existence of the child. The purpose of this study was to determine the factors that cause children to become victims of sexual violence and to take action against children as victims of sexual violence in the COVID-19 pandemic situation. This research method uses empirical juridical. Data collection is done by literature study and interviews. Data analysis used descriptive analytical method with a qualitative approach. The results of this study indicate that the cause of the increase in children as victims of sexual violence in the Covid-19 pandemic situation is because the implementation of the action still does not provide preventive and repressive protection. Victims and families of victims of sexual violence who are unable to report and do not know how to report the procedure for sexual violence experienced by the child, victims of sexual violence against children who often do not provide information openly, lack of facilities and infrastructure as well as human resources in regional institutions, are the obstacles found. Thus, there is a need for socialization and new innovations to the community, as well as the allocation of funds to regional institutions to maximize prevention and prosecution of children as victims of sexual violence in the COVID-19 pandemic situation.


Takes DICOM images as study objects, discusses a special way on the basis of an algorithm for extraction of fuzzy boundary to realize the extraction of boundary in medical image. By using this method, a DICOM image can be conversed into the BMP image format and be saved. At last, the effect of the method was showed by an instance.


The concept of network connectivity is applied to inorganic oxide glasses of hybrid structure. In order to describe these materials which are ripe for investigation, a new terminology is put forward. By using this terminology, some new lines of research can be readily identified. The way in which the physical properties of these novel materials will change with structure is discussed in broad terms, with particular reference to the glass transition temperature.


The ability of distributed generation sources to enhance the power quality of micro-grids is an important issue for the emerging power grid. This paper proposes a decentralized approach for power quality improvements in smart micro-grids. In this scheme, a modified reduced-order digital adaptive notch filter has been introduced and employed to extract the harmonic content of power system variables such as current or voltage. A universal digital power processor has been developed accordingly to intensify the power quality enhancement capabilities of distributed generation systems. The proposed technique allows for compensation of either particular unwanted frequency components or a wide range in the spectral content of the injected current. Current harmonics of non-linear local loads have been therefore compensated by the distributed generation source and a quality electric power is injected to the grid. Simulation results verify the accuracy and validity of the proposed scheme.


This chapter examines masters' statements on the specific structure of human speech and their views on the vocal utterances in the animal kingdom. The expressions of human are based on a wide range of terminological and conceptual instruments. The key words in it are its Latin form according to vox ("vocal utterance", "word") and sermo ("speech", "talk") or locutio (loquela, loqui) ("speaking"). The chapter presents a discussion on origin of speech and language and linguistic diversity. According to Albert the Great, the ability to speak is a uniqueness of human capability, the concept of the order of nature. Through them he shares his peers, his thoughts and emotions. The chapter analyses the differences between human and animal vocal utterances. It observes that certain animals seem to mimic human speech and understand in some way. The original text of the chapter is in German.Keywords: animal kingdom; human speech; language diversity; linguistic diversity; vocal utterances


A series of eighteen novel 3,5-bis(arylidiene)-4-piperidone based symmetrical monocarbonyl analogs of curcumin were synthesised and a subset was screened by National Cancer Institute (NCI), USA for their anticancer activity. Dose–response studies and the mechanism of action investigation suggest that most active compounds are apoptosis inducers.


With social- economic development, people's wealth accumulation continuously accelerates, making them pay attention to their asset allocation. There are many ways people can allocate their personal assets. Such as stocks, funds, bonds , and so on. But at the same time, a large number of people do not know how to use these tools correctly to make their asset allocation situation better. More professional and systematic educational guidance may lead people to allocate the most suitable asset allocation portfolio for them.


We present an effective method to suppress the hole overflow in Si quantum dots-based silicon nitride (SiN) light-emitting diodes (LEDs) by employing nanocrystalline Si (nc-Si) layer as hole blocking layer inserted between the SiN luminescent active layer and p-Si anode. The proposed devices exhibit strong white light emission under forward bias conditions. In comparison to the LEDs without nc-Si interlayer, a significant enhancement of more than 200% in light emission efficiency is achieved from the proposed devices. The increment in EL efficiency is found to strongly depend on the thickness of nc-Si interlayer. Besides, the proposed devices show a low turn-on voltage of 6 V, which is the same as that of the device without nc-Si interlayer. The analysis of the dominant recombination process indicates that the improved emission efficiency is resulting from the increased bimolecular radiative recombination probability, which is attributed to the effective hole-blocking effect of nc-Si barrier that mitigates the unbalance injections between electrons and holes in the SiN active layer by suppressing hole overflow.


Measurements of absolute cross sections for the single electron detachment ({sigma}{sub -1,0}) in collisions between H{sup -} and Ar in the energy range 5-50 keV are reported. A well-collimated H{sup -} ion beam is directed toward an Ar gas target and all three of the exiting scattered beam components (i.e. H{sup 0}, H{sup +} and H{sup -}) are measured simultaneously. Using the closure relation among the collision beam components, (H{sup 0}, H{sup -} and H{sup +}) the neutral detection efficiencies are determined at each energy and thereby we are able to report absolute single detachment cross sections. The single detachment cross sections {sigma}{sub -1,0} exhibit a broad maximum with a value of 1.78 x 10{sup -15} cm{sup 2} at an impact energy of 25 keV.


Karel "Vet Piet" Kleinman shows a small assegai and an whetstone of San origin found at the archaeological site of the ǂKhomani San 's former living area near Mbiwe.Images from this trip document the first excursions into the Kgalagadi Transfrontier Park and were a central part of the work on oral history and mapping in the first years of research.


Introduction:  Cumulative sum (CUSUM) analysis is used to assess competency in practical procedures. Previous studies have used CUSUM to assess competence in administering labour epidural, but these assessments were mainly performed with novice trainees. Different acceptable failure rates for the same procedure, such as administering labour epidural, have been used. In this article, we describe our experience of using CUSUM for the continuing assessment of competence among experienced trainees. We also tested the hypothesis that setting different failure rates can lead to different conclusions about a trainee's competency.


Dames and Moore assessed the environmental impacts associated with development of 37 projects planned or conceived for Commencement Bay study area. Elements of the natural and human environments assessed for each project included fish, invertebrates, birds, water quality, sediment quality, wetlands, land and water use, noise, and recreational, historic, archaeological, and aesthetic resources. Baseline data against which project impacts were assessed were developed from the COBS I effort and other studies performed in the study area.


Traditionally, the literature on water management has considered water from a techno-realist point of view by focusing on finding the most effective technical solutions to distribute the largest quantities of water among populations. This paper takes an alternative position by suggesting that particular "ways" of managing water are culturally embedded and that water management practices stem from an underlying hydro-mentality among water users and system designers. To this end, we explore two different water systems in Sri Lanka and argue that each system is underpinned by a particular hydro-mentality that influences the ways in which water is managed by downstream communities.


This study aims to: first, find out the types of soft skills needed by FKIP UMS accounting education students in 2018. Second, know the accounting learning model in an effort to instill soft skills for students in accounting learning in KD financial statements. Third, know the obstacles and evaluation in developing soft skills of accounting education students of FKIP UMS 2018 in learning accounting in KD financial statements. This type of research is a qualitative approach. The objects of this research are Accounting Education Students of FKIP UMS the 2nd semester and the 6th semester, Lecturers of Trade Accounting and FKIP UMS Accounting Education Services. The results of the study revealed the soft skills instilled by lecturers to students include the ability of honesty, accuracy, discipline, tidiness, skills, and cooperation. The way to instill soft skills is by using lecture learning models and problem based learning, namely by directly delivering values and assigning tasks and discussions. Obstacles in the effort to plant are the lack of facilities from the university and the allocation of time that is not in accordance with the amount of material. Evaluations carried out: 1) give subtle rebuke to students who are not focused, 2) give routine assignments to students, 3) ask students to document the results of their work.


Abstract : SPACECAST 2020 was a Chief of Staff of the Air Force (CSAF)-directed space study, challenged to identify and conceptually develop high-leverage space technologies and systems that will best support the warfighter in the twenty-first century. The study produced a series of white naners which have been assembled into clusters of concern for future space capabilities. Volume I consists of 11 unclassified white papers: Leveraging the Infosphere: Surveillance and Reconnaissance in 2020; Space Traffic Control: The Culmination of Improved Spave Operations; 21st Century Weather Support Architecture; Space-Based Solar Monitoring and Alert Satellite System; Space Weather Support for Communications; Spacelift: Suborbital, Earth to Orbit, and On Orbit; Unconventional Spacelift; Rapid Space Force Reconstitution (RASEOR); Space Modular Systems; Professional Military Education (PME) in 2020; and Preparing for Planetary Defense: Detection and Interception of Asteroids on Collision Course with Earth. The Volume also contains an Operational Analysis and listings of Project Contributors and Project Participants.


A series of poly(propylene) silica-grafted-hyperbranched polyester nanocomposites by grafting the modified hyperbranched polyester (Boltorn™ H20), possessing theoretically 50% end carboxylic groups and 50% end hydroxyl groups, which endcapped with octadecyl isocyanate (C19), onto the surface of SiO2 particles (30 nm) through 3-glycidoxy-propyltrimethoxysilane (GPTS) was prepared. The effect of silica-grafted-modified Boltorn™ H20 on the mechanical properties of polypropylene (PP) was investigated by tensile and impact tests. The morphological structure of impact fracture surface and thermal behavior of the composites were determined by scanning electron microscopy (SEM) and differential scanning calorimetry (DSC), respectively. The melt viscosity of composites was investigated by melt flow index (MFI). The obtained results showed that: (1) the modified Boltorn™ H20 was successfully grafted onto the SiO2 surface confirmed by FT-IR and X-ray photoelectron spectroscopy (XPS) analysis; (2) the incorporation of silica-grafted-modified Boltorn™ H20 (3–5 wt% SiO2) greatly enhanced the notched impact strength as well the tensile strength of the composites; (3) the incorporation of silica-grafted-modified Boltorn™ H20 had no influence on the melting temperature and crystallinity of PP phase; (4) the MFI of PP composites increased when the silica-grafted-modified Boltorn™ H20 particles were added compared with PP/SiO2 or PP/SiO2-GPTS composites. Copyright © 2004 John Wiley & Sons, Ltd.


Summary. Absolute and mutual constraints on radioactive heat productivity, plate thickness and steady state continental geotherms are demonstrated for a model in which heat productivity comprises a near-surface, exponentially decreasing component and a component independent of depth. For a given surface heat flux there are separate upper limits on each component and a limiting trade-off curve between them. Below these limits there are linear trade-offs imposed if either the plate thickness or the temperature at a given depth are known, and, in principle, tighter bounds are imposed on each component. Preliminary application of the model shows that a kimberlite pyroxene geotherm requires a plate at least 200km thick and that lower plate (upper continental mantle) heat productivities may be (but are not required to be) as great as about 0.1 yW m3, which is about ten times the heat productivity of chrondrites. The estimation of continental geotherms depends strongly on assumptions about the vertical distribution of radioactive heat sources in the continental plates and on whether or not a steady state is assumed to have been achieved. The thickness of the plate is also directly involved, since the base of the plate can be defined as the depth at which a characteristic temperature is reached. It is the purpose of this paper to demonstrate, using a simple but plausible model, the relationships between temperature, heat production and plate thickness, including some absolute limits on heat production. The relationships can be used to evaluate the implications of various independent estimates of these quantities, and some examples are discussed here. An obvious limit on heat production is that in the steady state no more heat can be generated in the plate than emerges at the surface. A constraint with less obvious implications is that the geotherm must reach the mantle temperature at a reasonable depth. These constraints will be demonstrated here using a simple model of heat source distribution which is nevertheless plausible enough to give quantitatively useful results. Attention will be confined here to steady state models. Although the possibility of indefinitely continued cooling and thickening of the continental plates has been discussed (Pollack & Chapman 1977), a severe problem with this hypothesis is that the associated thermal subsidence should be accompanied by lOkm or more of crustal thickening, a


A new type of 3-phase AC 2-degree freedom radial hybrid magnetic bearing(HMB) is proposed,for which the embedded permanent magnets provide a constant static biased flux and 3-phase coils generate the control flux.The mathematics expressions of biased flux were deduced by using the method of equivalent magnetic circuits,and mathematics models of radial magnetic suspension forces were deduced.According to the performance demand of the experiment rig,the parameters of the HMB and the control system were designed,the control system was constructed with Matlab/Simulink toolbox,and the start-up performance of the rotor suspension and character of rejection disturbance were simulated.The flux of prototype and attractive of the rotor were calculated and analyzed by using ANSYS8.0 finite element analysis software,and the results show that the design on this HMB is correct.


The invention discloses an automobile cigar lighter connecting line. The automobile cigar lighter connecting line includes a cigarette lighter plug, a transmission line and a plurality of adapter plugs; one end of the transmission line is connected with the cigarette lighter plug, and the other end of the transmission line is connected with the plurality of adapter plugs; the cigarette lighter plug is provided with an indicating lamp; the joint of the cigarette lighter plug and the transmission line is sealed through an insulating rubber sleeve; the conductor of the transmission line is sleeved with an insulating layer; the insulating layer is sleeved with a hard protective layer; the protective layer is sleeved with a middle wrapping layer; the middle wrapping layer is sleeved with a fire-proofing high temperature resistant layer; and the fire-proofing high temperature resistant layer is sleeved with an outer sheath. The automobile cigar lighter connecting line of the invention is advantageous in higher safety.


Objective To discuss the affection of cesarean for gynecological re-operation.Methods 58 patients after conventional cesarean section,76 patients after modern cesarean section,and other 60 patients without surgery before,were compared the situation intraoperative and postoperation with gynecological surgery again.Results Compared with normal control group,patients with cesarean section before that have significant difference in open time,bleeding,operation time,pelvic and abdominal conglutination and postoperative recovery (P 0.05 or P 0.01).And there were more serious in pelvic and abdominal conglutination in modern cesarean section group (P 0.05).Conclusion Cesarean section will increase the difficulty and risk in gynecological re-operation.


We study the relatively isolated galaxy NGC 3344, classified as SABbc, as part of our study of ringed isolated non- barred galaxies. This galaxy shows an inner and an outer ring, together with a small bar inside the inner ring. This bar is too small to relate it directly to the formation of the outer ring and we explore here its origin through HI (WSRT) line data together with broad band BR CCD-photometry and optical spectroscopy. We show that the bar is exponential and dominates the cen- tral parts, while the bulge component is small. This suggests a morphological type later than Sbc for NGC 3344, further sup- ported by the strong abundance gradient reported in the literature for this galaxy. The inner ring defines the beginning of the spiral structure which partially wraps around this ring at small radii. Less than 1% of the HI is located in this ring which is mostly composed by a young stellar population. The outer ring shows colours similar to those of the inner ring, indicating that is actively forming stars. It is not located symmetrically with respect to the center of the galaxy, its center being shifted by about 18 00 . Twenty percent of the HI emission is concentrated in this ring. The atomic gas is distributed asymmetrically in NGC 3344, extending 20% farther to the SE than in the opposite direction. The outer parts of the velocity field also deviate from that of a disk in circular rotation, with a pronounced warp especially abrupt to the SE. We derive a mass model for this galaxy, but the deviations from axisymmetry prohibit a good determination of a single pattern speed explaining the location of the rings.


Every modern-day nation state conducts nowadays social policy. However, it is on the basis of the "principles of equality of opportunity, equitable distribution of wealth, and public responsibility for those unable to avail themselves of the minimal provisions for a good life" (Britannica Online Encyclopaedia, 2014) that make him a welfare state. In this vein British sociologist Thomas Humphrey Marshall (1950) identified the welfare state as a special and distinctive combination of democracy, welfare and capitalism. Building on this, welfare states and their services all across the European Union have been facing several challenges and pressures since the 1975s. Theoretical questions centre if voters are therefore satisfied with what the welfare state services (still) achieves and if not if they hold politicians for their respective actions account. Conducting multiple regression analysis showed that there is link between welfare state service satisfaction and support for the governmental parties during elections through EU15 countries. However, analysis also implies that there is significant country variation in their actual magnitude. In addition to that the increasing embedded nature of the welfare state in the multi-level governance system of the European Union has hardly any influence on the relationship but instead other variables like the educational level of the voter and the trust in the countries parliament has a significant influence on the relationship.

Keywords: Welfare State Service Satisfaction, Electoral Accountability, EU15, Representative Democracy


Cationic polymers are being developed quickly as gene delivery vectors. For in vivo gene delivery, the cationic polymers are usually further modified by hydrophilic polymer grafting or ligand conjugation, which have been shown to increase the vector stability, gene delivery efficiency and specificity greatly. Some previous research had shown that modified hydrophilic polymer may partly shield the targeting ligand and result in poor delivery specificity. Developing a method to evaluate the influence of PEG modification on targeting delivery is particularly critical to cationic polymer design and gene therapy development. One of most commonly used cationic polymer polylysine (PLL) was chosen as a model. Targeting ligand epidermal growth factor(EGF)was conjugated with PLL to form PLL-EGF. Then hydrophilic polymer polyethylene glycol (PEG) with molecular mass 7 000 and 20 000 were used to modify PLL-EGF respectively to generate PEG7000-g-PLL-EGF and PEG20000-g-PLL-EGF. In BIAcore experiments, epidermal growth factor receptor (EGFR) was conjugated onto BIAcore chip and various PEG modified PLL-EGF solutions were flowed over the chip. By observing the change of RU value, the specific interaction of EGF to EGFR was compared. Compared with PLL-EGF, PEG modified PLL-EGF showed lower association rate and higher disassociation rate to EGFR. Furthermore, compared to PEG7000 modified PLL-EGF, PEG20000 modified PLL-EGF got lower association rate and higher disassociation rate to EGFR. The Scatchard analysis results showed that the interactions between EGFR and PLL-EGF or PEG-PLL-EGF are non-linear. It can be concluded that PEG modification indeed reduced the association rate and enhanced the dissociation rate of EGF to EGFR. The length of PEG chain was also a key factor to influence interaction between ligand and receptor. The results showed that it was critical important to evaluate the influence of PEG modification on delivery specificities. The BIAcore method developed in this paper can successfully evaluate the influence, which would be important for cationic polymer design and its application as potential non-viral gene delivery vectors.


The evaluation of an advanced software engineering (SE) course is a challenging task that should be addressed as part of the course design. In this paper, we describe an implementation of the reflective practitioner perspective as part of an advanced SE course and introduce its use for feedback purposes. Reflective feedback goes beyond merely using feedback questionnaires. Furthermore, we show, using both qualitative and quantitative empirical data, that the course on which the perspective was applied meets its objectives and fosters students' awareness to the multidimensional nature of SE.


Doctors deal with complementary medicine in a variety of professional situations. Patients may ask for advice about whether to pursue complementary therapies or which therapist to consult; they may request referral or delegation, either privately or on the NHS; or they may want to discuss treatment or advice given by complementary practitioners. Doctors prescribing drugs to patients taking complementary treatments may have concerns about possible interactions. Doctors should therefore consider strategies for minimising risk and facilitating sensible and appropriate discussions with patients and complementary practitioners.

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Most patients do not tell their general practitioner if they are using complementary medicine. This may place some at unnecessary risk

Surveys of doctors' attitudes to complementary medicine show that, overall, physicians believe it is moderately effective, but low response rates make some studies unreliable. Although hospital doctors and older general practitioners tend to be more sceptical than younger doctors and medical students, most respondents believe that some of the more established forms are of benefit and should be available on the NHS. Younger doctors and medical students are more likely to perceive their knowledge of complementary medicine as inadequate and to want more tuition in the subject.

#### Common concerns of doctors about complementary medicine

Qualitative research shows that many doctors want to be supportive of patients' choices and would welcome further information, although they generally regard complementary therapies as scientifically unproved. Doctors' concerns about such therapies include whether they are used as an adjunct or an alternative to conventional care, how effective conventional treatments are in the given condition, and the possibility …

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Purpose: To investigate the expression of IRF-1, IRF-7 and iNOS in the mice model of Pseudomonas aeruginosa keratitis. The enzymatic activity of iNOS and its expression were also investigated. Methods: With western blot analysis, the protein expression of IRF-1, IRF-7 (at 24 hours), and iNOS (at 12 hours and 24 hours) were evaluated in the mouse model of P. aeruginosa keratitis. iNOS enzymatic activity was determined with a scintillation counter. IRF-1 and IRF-7 expression were localized with immunofluorescent labeling. The wounded control group was given the same corneal wound without bacterial inoculation, and the fellow eyes served as normal controls. Results: Expression of IRF-1, IRF-7 and iNOS was highly upregulated in corneas with P. aeruginosa keratitis compared to normal or wounded corneas. iNOS enzymatic activity also was higher in infected than normal corneas. In wounded corneas, NOS2 expression and activity slightly increased at 12 hours after the infection. Intense IRF-1 immunopositivity was seen in the epithelial layer of infected corneas. Some corneal stromal cells and endothelial cells showed moderate positive labeling in infected corneas. IRF-7 showed intense labeling in the epithelial layer and endothelial cells of normal as well as infected corneas. Increased IRF-7 labeling was observed in epithelial cells in the ulcerated region of infected corneas. Conclusions: These results suggest that IRF-1, IRF-7 and iNOS may play a regulatory role in the immune responses and wound healing process in P. aeruginosa keratitis.


In this paper, the uncovered interest rate parity (UIP) assumption, using a well-known 3D chaotic dynamical system, which describes the variations of the interest rate, is studied. More specifically a 4D novel hyperchaotic financial system is proposed by introducing the exchange rate, due to the fact that the difference in interest rates between two countries is equal to the relative change in currency foreign exchange rates over the same period. The novel 4D financial dynamical system is investigated in two different cases with and without a base interest rate. The system's hyperchaotic behavior and a route to chaos through a crisis phenomenon and quasiperiodic behavior are observed through the simulation results. Keywords—Econophysics, exchange rate, hyperchaotic finance system, interest rate.


The present study tried to identify the whole experience of care of a terminal ill person with an imminent death phase, by means of a qualitative design, with kind of phenomena focusing, in order to strengthen the nurse care starting from the person's reality. It is made from a state of art exhaustive review, which is part of the study of phenomena, which enables to validate and make a contrast by the results done through the research. In the study, 13 people with chronic illness and imminent death phase participated, with whom a saturation of information was reached; the interviews were transcribed and analyzed, using the phenomenal analysis method in accordance with Streubert (1991). The result of the research was done with an ample description of the different categories, which defined the experience of home care from the psycho-emotional and physical point of view, and which at the same time have a relationship between them and requires of an emotional care, as an indispensable component within the death phase experience in a honorable way, most remote as possible from suffering.


sentatives should choose among competing alternatives in matters of public policy. Are representatives to choose what is in the people's true interest or are they to choose the expressed desires of the people? People normally understand a representative as someone who does solely what her constituents expressly demand or desire. Sometimes, as a result of lack of adequate knowledge of their true interest, it may turn out that their expressed interest or desire may not capture their genuine or true interest. It is also sometimes difficult to know what people's desires are with respect to matters of public policy, because there is usually no approximate unanimity or majority agreement on a specific desire or interest. Moreover, their desires or interests may be at odds with the national interest. The contemporary American philosopher J. Roland Pennock addresses these problems regarding political representation. He starts by addressing the question of what it means to represent others. In doing so, Pennock does a conceptual analysis of the notion of representation by articulating what a representative must do in order to be deemed a responsible official who truly represents other people or their interests. Pennock articulates a set of norms or prescriptions that officials must abide by in order to truly undertake the task of representing others. The set of norms, Pennock argues, applies to all people or officials in government—even those who are not elected. He argues that the normative notion of representation applies to both elected officials in a democratic context and non-elected officials; indeed, all officials in government may serve in representative functions without being necessarily elected. They are representatives in the normative sense of abiding by a set of norms. Pennock argues that a Hobbesian Leviathan or medieval king had some legitimate authority in the sense in which he may be said to be representative of the people he has authority over. The notion of legitimacy or representation has a normative basis which requires that a representative supports, stands for, and is responsive to the interest of the represented, and that the representative is in some sense authoPOLITICAL REPRESENTATION: AN OVERVIEW J. Roland Pennock


Low error rates were obtained from the transmission of twenty 10 Gb/s channels with 100 GHz spacing over four 80 km (25 dB) spans of dispersion shifted fibre (DSF) in the lower wavelength region of the L-band where the effects are largest due to lower dispersion.


After a discussion of the two concepts of college knowledge management and knowledge management culture, the present author points out that learning and research is the core of knowledge management culture and that thus, the most successful college in the 21st century is the learning-type organization with learning-research culture. The article also illustrates the approach to the establishment of knowledge management system in college.


Hydrogen embrittlement of high-strength steel (4340M) was quantified through tensile testing and fractography (SEM). Three types of samples were obtained: rotating beam fatigue specimens, round (notched) tensile specimens, and flat panel specimens. In addition, three different plating types were analyzed (Ni, Cr, Cd-Ti) with a set of samples that was shot peened and a set that was not. Since some of the samples went through a hydrogen relief bake, another factor in our experiment was the amount of time it took for the samples to reach the baking process after they were electroplated (bake delay). There were three levels of bake delay that were studied for each type of plating: specified bake, delayed bake, and no bake. The notched tensile specimens and the rotating beam specimens were tensile tested, and their fracture surfaces were imaged and analyzed. The flat panel specimens were notched and manually fractured in a vise, and fractography was performed to characterize failure modes. To determine the amount of hydrogen input and release from the various samples, LECO combustion analysis was performed. The hydrogen content was used to correlate the various processing conditions (electroplating type, shot peening, bake delay) to their tensile properties and failure modes. ii Acknowledgements We would like to thank The Boeing Company for sponsoring this project, and especially our industry contacts Craig Dickerson and Bob Weiss. We appreciate the opportunity and the help received throughout the process of completing this project. We would also like to thank the Materials Engineering department for allowing us to utilize their equipment and facilities. We would also like to thank Luka Dugandzic for manufacturing the attachments for the button head fixture and Wyoming Test Fixtures for providing this fixture. Lastly, we would like to thank Professor Blair London, our senior project advisor, for his support and guidance in completing the project.


In brief The effects of routine IV fluid therapy on blood biochemical values in collapsed runners have not been studied. We measured serum sodium concentrations and other indicators of fluid status in 32 collapsed and 16 noncollapsed runners after a 56K race. Twenty-six (81%) of the collapsed runners received IV fluid therapy, some at the discretion of the attending physician. Profound hyperglycemia developed in all 26 and marked hyponatremia in 14 (54%), whereas blood glucose and serum sodium values remained within the normal range in the 6 untreated collapsed runners.


We consider a system composed of two different types of particles that have different radii, but equal density. Both particles experience gravity and a linear drag force from the interstitial fluid. They are excited by a boundary that vibrates with high frequency and adds sufficient energy that the particles near the boundary become highly dilated. For moderate energy input rates we show that a single large particle introduced into a large number of small particles will rapidly move to a fixed height and remain approximately stationary. In particular, the large particle will never come into contact with the vibrating base. If there are a large number of large particles, then this behavior leads to a very distinct segregation in which the large particles are sandwiched between two layers of small particles. We show that this behavior occurs as a direct result of non-equilibrium effects and develop a simple phenomenological model that gives good predictions of the height at which the sandwiched layer occurs.


Graphene nanoscroll (GNS) is an important one-dimensional tubular form of graphitic carbon with characteristic open topology. It has been predicted to possess extraordinary properties that are significantly different from the analogical multiwalled carbon nanotubes. However, comprehensive experimental investigations on its properties and applications are still hindered by the lack of its reliable synthesis in high yield. To efficiently transform the scalable graphene oxide sheets into GNSs, here, we proposed a well-controlled lyophilization that comprises four sequential steps: chemical reduction of giant GO, freezing isolation of reduced graphene sheets, freeze-drying, and thermal annealing. The combined method has an extremely high efficiency, up to the record 92%. Systemic control experiments and cryo-SEM inspections revealed that the topological transformation from 2D sheet to 1D scroll is the sublimation-induced scrolling of individually confined graphene sheets in ice, which was controlled by chemic...


Biomaterial surface properties, via introduction of specific signal biomolecules can influence cell adhesion and differentiation processes. Inspired by the monosaccharide motifs found in collagen glycosylation patterns, galactose being one of the most commonly found saccharidic residues, collagen matrices were modified in order to expose galactose residues to cells. The interaction of chemically neoglycosylated matrices was evaluated with osteosarcoma-derived cell line MG63.


Noise measurements on a distributed erbium-doped fibre amplifier are reported for the first time. Data are presented for fibre lengths up to 54 km, and are in good agreement with theoretical predictions. >


The last 15 years have brought cellular voice and SMS communications to the masses with 5 billion connections worldwide. An extensive supply ecosystem is facilitating a new revolution in wireless with smartphones and mobile broadband. Innovation in wireless, as with the Internet, is being driven by "upstream" specialists including global technology vendors, overthe-top mavericks and a plethora of applications developers in all shapes and sizes. Carrier innovations tend to be commercial rather than technological.


Abbreviations Preface 1. The World and the Thing: Of Signification and Nature 2. Lacan and Heidegger on the Thing 3. Levinas and Heidegger: The One and the Incompleteness of Beings 4. Between Nature and Culture: Heidegger and Zizek on the Thing and the Subject 5. Heidegger and Marxism: 'a productive dialogue' Bibliography Acknowledgements Index


According to specialities and practical requirements of enterprise manager assessment and evaluation,a B/S-based assessment and evaluation system was designed on.Net platform.Adopting a three-layered architecture containing Representation Tier,Business Tier and Data tier,the services application was designed on the server with modularization and component method.Combining a factory design pattern and the reflection mechanism,a dynamic data access tier was produced,which really separated the implements of data tier and upper tiers.