In this paper, the problem of reducing control points for surface reconstruction is addressed. A new parameterization method considered as hybrid method for NURBS surface is presented. This method allows multiple knots, and very close domain knots. The proposed method and another three conventional methods (uniform, cord length and centripetal) are applied to reduce the data point within prescribed error tolerance without sacrificing the shape of the original object. The results for different objects show that the hybrid parameterization is capable of giving reasonable reduction while preserving the object shape.


The energy of infared and millimeter radiation is well suited to elementary excitations in solids and provide in this way an excellent tool to investigate the corresponding physical mechanism by resonant and nonresonant spectroscopy. Due to the large number of competing transitions caused by different physical processes the experimentalist envisages quite often the problem to identify correctly the resonance structure in question. Magnons, quasi-free carrier transitions, phonons and impurity excitations superimpose within the spectrum of experimental data. This means that there is need for a filter to discriminate the transition in question from the other perturbing effects. In many cases magnetic fields provide this filter function, if the energy levels involved can be tuned by those fields.


Background Tocilizumab (TCZ) has proved to be effective in the management of Giant Cell Arteritis (GCA). Based on results of the GiACTA trial, it has been approved by the FDA and the European Commission for GCA treatment. Nevertheless, almost half of the GiACTA trial patients presented a short time evolution disease. Objectives Our aim was to evaluate the efficacy of TCZ according the time of disease evolution. Methods Retrospective, multicenter study of 134 patients with GCA in treatment with TCZ. A comparative study between two groups according to the time from disease diagnosis and TCZ onset was performed. Results Our study included 134 GCA patients. TABLE 1 summarizes a comparative study between: a) ≤ 6 months of disease evolution, and b) > 6 months of disease evolution. Non-significant difference in baseline characteristics was found. In terms of visual involvement, we observed more patients affected in the first group (≤ 6 months) (p=0.30). Analyzing clinical improvement non-significant difference was seen during follow-up. At TCZ onset, in the group of ≤ 6 months of evolution, the prednisone dose was higher with a mean dose of 31.3±16.5 mg/d vs 17.7±14.2 mg/d (p<0.001), however, a similar reduction of corticosteroids was achieved in both groups after 6 months of follow-up. The incidence of adverse events and severe infections was similar in both groups (p=0.132 and p=0.672 respectively). Conclusion In this retrospective analysis, our results support the previously reported efficacy and safety profile of TCZ. We can conclude that TCZ can be used in GCA independently the time of disease evolution. References [1] Calderón-Goercke M. Tocilizumab in giant cell arteritis. Observational, open-label multicenter study of 134 patients in clinical practice. Semin Arthritis Rheum. 2019Jan5. pii: S0049-0172(18)30571-7. Doi: 10.1016/j.semarthrit.2019.01.003. [Epub ahead of print] [2] Salvarani C, Magnani L, Catanoso M, Pipitone N, Versari A, Dardani L, et al. Tocilizumab: a novel therapy for patients with large-vessel vasculitis. Rheumatolgy (Oxford). 2012; 51:151-6. [3] Stone JH, Tuckwell K, Dimonaco S, Klearman M, Aringer M, Blockmans D, et al. Trial of Tocilizumab in Giant-Cell Arteritis. N Engl J Med. 2017; 377:317-28. Disclosure of Interests Monica Calderón-Goercke: None declared, J. Loricera: None declared, D. Prieto-Peña: None declared, Vicente Aldasoro: None declared, Santos Castañeda Consultant for: Amgen, BMS, Pfizer, Lilly, MSD, Roche, Sanofi, UCB, Ignacio Villa-Blanco: None declared, Alicia Humbría: None declared, Clara Moriano: None declared, Susana Romero-Yuste: None declared, J. Narváez Consultant for: Bristol-Myers Squibb, Catalina Gomez-Arango: None declared, Eva Perez-Pampín: None declared, Rafael Melero: None declared, Elena Becerra-Fernández: None declared, Marcelino Revenga: None declared, Noelia Alvarez-Rivas: None declared, Carles Galisteo: None declared, Francisca Sivera: None declared, Alejandro Olive: None declared, María Álvarez del Buergo: None declared, Luisa Marena Rojas: None declared, Carlos Fernández-López: None declared, Francisco Navarro: None declared, Enrique Raya: None declared, Eva Galindez: None declared, Beatriz Arca: None declared, Roser Solans-Laqué: None declared, Arantxa Conesa: None declared, Cristina Hidalgo: None declared, Carlos Vázquez: None declared, Jose Andrés Román-Ivorra: None declared, Pau Lluch: None declared, Sara Manrique Arija Speakers bureau: ABBvie, MSD, Janssen, Lillly, Roche, Pfyzer, Novartis., Paloma Vela-Casasempere Grant/research support from: UCB, Abbvie, Pfizer, Roche, Bristol-Myer-Squibb (another research, not BIOBADASER related), Consultant for: UCB, Lilly, Pfizer, Roche, Bristol-Myer-Squibb, Speakers bureau: Roche, UCB, MSD, Pfizer, GSK, BMS, Lilly, Eugenio de Miguel: None declared, Carmen Torres-Martín: None declared, Juan Carlos Nieto: None declared, Carmen Ordas-Calvo: None declared, Eva Salgado-Pérez: None declared, Cristina Luna-Gomez: None declared, Francisco J. Toyos Sáenz de Miera: None declared, Nagore Fernández-Llanio: None declared, Antonio García: None declared, Carmen Larena: None declared, Natalia Palmou-Fontana: None declared, Vanesa Calvo-Río: None declared, Carmen González-Vela: None declared, Alfonso Corrales: None declared, María Varela-García: None declared, Elena Aurrecoechea: None declared, Raquel Dos-Santos: None declared, Ángel García-Manzanares: None declared, Norberto Ortego: None declared, Sabela Fernández: None declared, Francisco Ortiz-Sanjuán: None declared, Montserrat Corteguera: None declared, J. Luis Hernández: None declared, Miguel A González-Gay Grant/research support from: Prof. MA Gonzalez-Gay received grants/research supports from Abbvie, MSD, Jansen and Roche., Speakers bureau: Consultation fees/participation in company sponsored speaker's bureau from Pfizer, Lilly, Sobi, Celgene, Novartis, Roche and Sanofi., Ricardo Blanco Grant/research support from: Abbvie, MSD, and Roche, Consultant for: Abbvie, Pfizer, Roche, Bristol-Myers, Janssen, Speakers bureau: Abbvie, Pfizer, Roche, Bristol-Myers, Janssen


Two online projects are described in this paper. Wara Blong Life and Sniff, Swing and Swipe were ten-week, online activity-based projects offered in 2001 to elementary, middle and junior secondary school classes from all over New Zealand.


The empirical asset pricing literature documents a myriad of anomalies. Accounting for the correlated and mean-reverting nature of these anomalies, I provide an explicit solution to the optimal dynamic investment problem of a risk-averse investor who trades in an arbitrary number of potentially mispriced assets. The solution can be characterized in terms of a passive and an active portfolio, where the active positions respond to market-timing and stock-selection considerations. Mispricing risk can have a large impact on the investor's optimal portfolio, which the investor hedges by increasing the size of the position in the mispriced asset. When the market portfolio is subject to mispricing, market-timing and stock-selection considerations interact to determined the optimal position in each asset. I show that diversification considerations can lead the investor to optimally take a positive active position in an overpriced asset, and even to increase the allocation in this asset as overpricing worsens. These results have important positive and normative implications.


Purpose: Optimal fixation for comminuted proximal humerus fractures is controversial. Complications using locked plates have been addressed by anatomic reduction or medial cortical support. The current study measured relative mechanical contributions of varus malalignment and medial cortical support. Method: Forty synthetic humeri were divided into three groups, osteotomized, and fixed at 0, 10, and 20 degrees of varus malreduction with locked proximal humerus plates (AxSOS, Global model, Stryker, Mahwah, NJ, USA). This simulated mechanical medial support with the cortex intact. Axial, torsional, and shear stiffness were experimentally measured. Half of the specimens in each of the groups underwent a second osteotomy to create a segmental defect which simulated loss of medial support with the cortex removed. Axial, torsional, and shear stiffness experiments were repeated, followed by shear load to failure in 20 degrees of abduction. Results: For isolated malreduction with the cortex intact, the repair construct at 0 degrees showed statistically equivalent or higher axial, torsional, and shear stiffness than other groups assessed. Subsequent removal of cortical support in half the specimens resulted in a drastic effect on axial, torsional, and shear stiffness at all varus angles. Repair constructs with the cortex intact at 0 and 10 degrees resulted in mean shear failure forces of 12965.4 N and 9341.1 N, respectively. These were statistically higher (p Conclusion: Anatomic reduction with the medial cortex intact was the stiffest construct after a simulated two-part fracture. This study also supports the practice of achieving medial cortical support by fixing proximal humeral fractures in varus if necessary. This may be preferable to fixing the fracture in anatomic alignment when there is a medial fracture gap.


Genotypic variation in the capacity of plants to absorb, translo cate, and use mineral nutrients has been the subject of many in vestigations since initial reports in the 1920s and 1930s (5, 6). However, it has only been within the past 15 to 20 years that researchers have made concerted efforts to understand and exploit genetic differences in plant nutrition as a means to improve crop production. Slow progress in this area can be attributed to emphasis on amending soils for plants rather than selecting plants for partic ular soil conditions (1-3, 7, 17). Lack of a clear understanding of mechanisms involved at cellular, tissue, and whole-plant levels has also impeded progress. Breeding for desirable nutritional traits in plants is, with few exceptions, a complex process, likely to involve more than one gene, and greatly affected by various environmental factors. Despite these challenges, there has been some success in breeding nutritionally improved genotypes (3, 7, 17). The use of soil amendments to replenish nutrients used by plants will always be an integral part of crop production, but it is now recognized that selecting plants for improved nutritional characteristics can be a viable and, at times, necessary alternative for increasing crop pro ductivity and enhancing crop quality. Two international symposia dealing with genetic aspects of min eral nutrition were held prior to this 1987 colloquium. A third was held in 1988. A major research focus, as reported at these meetings, has been the identification of genotypes tolerant to adverse condi tions, including salinity, acidity, alkalinity, and nutrient stresses (14, 17). Large quantities of Fe may be present in calcareous soils, for example, but the element is not available for uptake/use by many species or genotypes. Alternatively, high levels of an element in acid soils (e.g., A1 or Mn) may be present that can be toxic to some species or genotypes but not to others. The concept of efficient nutrient use, i.e., an increase in economic production per unit of available nutrient, has received considerable attention, particularly for low-input agriculture where fertilizer applications are not eco nomically feasible. Recent developments in the area of molecular biology also provide exciting possibilities for genetically manipu lating nutrient acquisition and transport by plant roots (10, 16). Proceedings from these two earlier symposia document research concerning genotypic differences in plant mineral nutrition, but few of the papers dealt specifically with horticultural crops. This is not to imply that advances in genetic control of mineral nutrition have not been made with horticultural crops. Indeed, tomato and bean plants were studied in much of the nutrient efficiency research that has contributed to renewed interest in breeding for nutritional char acteristics (8, 15). Other research with horticultural crops includes selection of salt-tolerant citrus rootstocks (12) and tomato genotypes (13) and studies showing that inefficient B transport in celery and tomato may be due to a single recessive gene (11, 18). Although progress in genetic aspects of mineral nutrition of horticultural crops has been made, there are still many opportunities for further re search. Genetic manipulation of the mineral nutrition of horticultural crops may have an important impact in many different production areas. The potential for improving nutritional traits of horticultural crops is illustrated by the following examples: a) Certain physiological


Abstract The polymerization of cyclohexene oxide (CHO) by various organoaluminum compounds such as R3Al (R = Me, Et, i-Bu), Et2AlCl, and EtAlCl2 is reported. Ethyl-substituted aluminum compounds were found to be very effective for this polymerization. As more chlorine atom is substituted on the aluminum atom, the polymer yield was increased though the molecular weight was decreased. The polymer yields at varying monomer-to-catalyst mole ratios (M/C) were similar (80–93%). The temperature and solvent effect for the present polymerization were also studied. The present poly(CHO) was a less stereoregular (atactic) isomer, regardless of catalysts and polymerization conditions. The resulting poly(CHO) was a white powder ad was soluble in aromatic and halogenated hydrocarbon solvents such as benzene, chlorobenzene, CCl4, chloroform, etc.


Objective: To introduce a new effective operation method to correct inverted nipples. Methods: An arcoda transverse incision was designed to relax the base of nipples,then double figure-of-eight suture was performed to repair and reconstruct the inverted nipple.After procedures inverted nipple was erected for one week by outside traction. Result: Twenty-one cases of inverted nipples were followed up postoperatively from 3~24 months and almost all of them achieved satisfactory efficacies. Conclusion: This method is simple, safe, effective and also has some merits such as microcncision and few complication ets.


A one-dimensional oxygen depletion model was constructed for Cayuga Lake (upstate New York) for the period of summer stratification. A primary objective was to determine the relative importance of horizontal diffusion rates to planktonic and benthic respiration in the vertical. Terms in the one-dimensional diffusion equation account for sinking rate and consumption by respiration of algae, plankton, and benthos. A separate equation computes oxygen transport. The sensitivity of the model is tested with respect to the various parameters. Practical diffusion coefficients were obtained using a combination of methods. The results indicate that in Cayuga Lake all three of the depletion agents exert a large demand in the upper 30 m, the total uptake is small in the mid 70 m, but diffusion from this region into areas of the high demand is large, and the lowest 30 m is dominated by the benthic demand.


Study Design. A retrospective long-term follow-up study. Objectives. To report minimum 10-year follow-up results of posterior dynamic stabilization using Graf artificial ligament and to evaluate the role and limitations of this procedure in the treatment of degenerative lumbar disorders. Summary of Background. Motion-preserving surgeries, including artificial disc replacement and ligamentoplasty, are increasingly gaining interest to avoid adverse effects of spinal fusion, but literature addressing long-term results is sparse. Methods. A total of 56 consecutive patients who underwent Graf ligamentoplasty were reviewed at a minimum 10-year follow-up. Forty-three patients in the original cohort had sufficient clinical and radiographic follow-up for analysis. The pathologies included degenerative spondylolisthesis in 23 patients, disc herniation with flexion instability in 13 patients, spinal stenosis with flexion instability in 4 patients, and degenerative scoliosis in 3 patients. Single-level procedures were performed in 36 patients; multilevel procedures were performed in 7 patients. Radiographic and clinical assessments were performed before surgery and at the final follow-up. Results. Disability due to low back pain and/or sciatic symptoms was significantly improved in the patients with degenerative spondylolisthesis or flexion instability. However, degenerative scoliosis and/or laterolisthesis were associated with poor clinical improvement. In radiographic assessment, segmental lordosis was maintained in 10.9°, and flexion-extension motion was averaged 3.6° at the final follow-up. Facet arthrodesis eventually occurred in 14 patients (32.6%) at an average of 82 months after surgery. Additional surgeries were required in 3 patients (7.0%) for adjacent segment pathologies. Conclusion. The long-term results showed that Graf ligamentoplasty is an effective treatment option for low-grade degenerative spondylolisthesis and flexion instability. However, this procedure has limitations to correct spinal deformity, and is not advocated for the treatment of degenerative scoliosis and laterolisthesis.


"There may not be any book on architecture so delightful to dip into; one wishes there were a pocket edition to take on an Italian vacation--not only for its information and vision but for such pleasant reminders as that the citizens of Treviso carried Tullio Lombardo's friezes through the town in triumph before they were attached to a building."--D. J. R. Bruckner, "New York Times Book Review"


Kirby and Siebenmann have recently proved that every boundaryless topological n-manifold (n ?5) having trivial 4-dimensional Z2cohomology can be given a combinatorial triangulation; they have also given an example of a topological manifold which supports no combinatorial triangulation. It is quite possible, however, that the manifold constructed might be triangulable by a complex which is not a combinatorial manifold. The main purpose of this note is to show that if this could be done in such a way that the open simplexes are locally flat, then either the 3or the 4-dimensional Poincare conjecture would be false. Let us call such a triangulation locally flat; note that we do not require that the closed simplexes be locally flat. Then our main result is:


With the development of internet technology, a distributed automatic test system works in a local area network is on the date. There are very important to resolve the follow questions, how to manage the resource in the ATS, how to find and drive the instrument in the ATS. This article designs a distributed automatic test system based on the technology of distributed component object model and active directory Service.


Ad Hoc On-Demand Distance-Vector routing protocol provides fast and efficient route establishment between mobile nodes that need to communicate with each other. Since AODV has been specifically designed for ad hoc wireless networks, it has minimal control overhead and route acquisition latency. In addition to unicast routing, AODV supports multicast and broadcast as well. Moreover, AODV can be extended to support Quality of Service (QoS). The goal of this paper is to take a closer look at these QoS extensions. Since the QoS extensions are relatively new concept, it is not that clear yet how to properly utilize them. They may introduce some problems as well.


D 0 (cid:0) (cid:22) D 0 mixing leads to the mass and width di(cid:11)erences in the mass eigenstates of D 0 and (cid:22) D 0 mesons (measured by parameters x D and y D respectively), but their magnitudes cannot be reliably predicted by the standard model. We show that it is possible to separately determine x D and y D through time-integrated measurements of the dilepton events of coherent D 0 (cid:22) D 0 decays on the (4:14) resonance at a (cid:28)-charm factory.


Abstract : An apparatus to study the generation of plasma in air was designed, fabricated, and assembled. A 400-liter test cell was developed to study plasma in air which has a pressure that can be varied from standard atmospheric pressure at sea level to 1 mTorr at 300,000 ft. Plasma is generated by impact ionization of air due to bombardment by a 100-kev electron beam. Microwave diagnostics quantify electron number density and optical diagnostics quantify ozone production. A particle in cell plasma code (MAGIC) and an air-chemistry code are used to quantify beam propagation through an electron-beam transmission window into air and the volumetric ionization rate within the test cell. Sensors were developed to monitor beam current incident on a transmission window and the resulting plasma formed in air on the transmission side of the window. Diagnostics from multiple sensors are acquired simultaneously for studies of power required to generate and maintain plasma in air on the timescale of 1 ms.


Abstract : Sufficient conditions on a pair of functions in an interval are obtained so that all continuous functions in the interval can be approximated in a continuous way to any preassigned accuracy by piecewise linear combinations of the two. (Author)


The security evaluation for Mail Distribution Systems focuses on certification and reliability of sensitive data between mail servers. The need to certify the information conveyed is a result of known weaknesses in the simple mail transfer protocol (SMTP). The most important consequence of these weaknesses is the possibility to mislead the recipient, which is achieved via spam (especially email spoofing). Email spoofing refers to alterations in the headers and/or the content of the message. Therefore, the authenticity of the message is compromised. Unfortunately, the broken link between certification and reliability of the information is unsolicited email (spam).
Unlike the current practice of estimating the cost of spam, which prompts organizations to purchase and maintain appropriate anti-spam software, our approach offers an alternative perspective of the economic and moral consequences of unsolicited mail. The financial data provided in this paper show that spam is a major contributor to the financial and production cost of an organization, necessitating further attention. Additionally, this paper highlights the importance and severity of the weaknesses of the SMTP protocol, which can be exploited even with the use of simple applications incorporated within most commonly used Operating Systems (e.g. Telnet).
As a consequence of these drawbacks Mail Distribution Systems need to be appropriate configured so as to provide the necessary security services to the users.


The Early Cambrian(corresponding to Terreneuvian and Series 2)is an important sedimentary period of marine source rocks in Tarim area.Researches on the framework of ocean and continent in Tarim area will help estimate the potential resources of the rocks.Based on previous studies,the authors investigated and analyzed 13 outcrops and 10 borehole sections,and consulted some seismic sections.By means of an analysis of stratigraphic and petrologic characteristics,the map for oceanic and continental framework and tectonic-sedimentary environment of Tarim area was compiled.It is pointed out that the area around Tiemenguan was a micro-landmass.The authors consider that both Tiemenguan micro-landmass and North Kuluketage underwater platform belonged to North Tarim passive continental margin.Furthermore,the authors divided the Tarim epeiric sea basin into different sedimentary environment areas on the basis of new data.


Productivity is still an important performance measure for the firm level and macroeconomic level. This study addresses total productivity measurement based on RAPMODS using basic accounting data for Turkish manufacturing industry for the period of 2006 to 2016. The results obtained from the analysis allows us to understand the total productivity and the source of the productivity changes related to partial productivities of the Turkish manufacturing industry. Furthermore, the potential productivity improvement areas are interpreted owing to these results.


Based on the analysis of NC's feature and NC's effect on the net system performance,the author studies on the applied mode of NC in the focused industries and the solutions according to the applied feature of China's focused industries.The study is aimed to instruct the application of NC further.


Magnetic refrigeration requires a strong magnetic field and its alternation for the magnetization and demagnetization processes. In this paper, a conduction-cooled HTS magnet system was fabricated and tested for a magnetic refrigerator. It consists of a HTS magnet, a pair of metallic and HTS current leads, and a cryocooler. The Gd-Ba-Cu-O coated conductor with polyimide tape insulation was used for the HTS magnet and wound by standard layer-wound method. Stainless steel bore was assembled with OFHC copper supporting plates of the HTS magnet. The OFHC copper strips were inserted between interlayers of the conductors to enhance axial thermal conduction. Apiezon N grease with hexane solution was applied on every layer of the HTS magnet to minimize thermal contact resistance between the conductor and the OFHC copper strips. The HTS magnet was cooled to 17 K. The charging and discharging of the HTS magnet were achieved by the unipolar power supply and an external dump resistor. Stable magnetic field of 3.25 T was achieved with 150 A. Alternating magnetic field was stably generated with the peak of 2.16 T (0.11 T/s). In this paper, the fabrication method of AC magnet and the operational issues of the conduction-cooled HTS magnet are discussed.


Objective To observe randomly Lactobacillus capsule supporting the clinical efficacy of microwave treatment of cervicitis.Method 100 out-patients with cervicitis receiving microwave treatment in our hospital from January 2008 to December 2009 were randomly divided into two groups,control group(physical therapy group) and treatment group(physical therapy plus Lactobacillus vaginal capsule).Result The treatment group supported the efficacy of microwave treatment of cervicitis,compared with the control group,with fewer adverse reactions and faster disappearance of symptoms such as vaginal bleeding and discharge.And the difference was statistically significant(P0.01),Conclusion Microwave-assisted treatment of cervicitis with Lactobacillus capsule have positive efficacy with reduced postoperative bleeding and wound fluid as well as improved wound healing.


In this article, a protocol‐based H∞ filtering problem is investigated for piecewise linear (PWL) systems with mixed delays. Stochastic access protocol (SAP) is utilized to schedule the signal transmission via a constrained communication channel, under which only one measurement value can be transmitted to the filter at each time instant following a Markov process. When SAP is applied to PWL systems, only a part of system modes can be observed due to the incomplete measurement information. Therefore, a measurement‐dependent parameter storage rule with a certain probability distribution is introduced to overcome the difficulties coming from SAP‐induced incomplete information. By resorting to the proposed mode storage rule, a novel measurement‐dependent asynchronous H∞ filter model is constructed and the problem is converted into a new switching process of a larger state space following a reconstructed Markov process. Subsequently, a sufficient condition is established to guarantee the H∞ performance, and the probability‐dependent filter parameters are obtained by applying the stochastic analysis technique. Finally, a numerical example is given to show the effectiveness of the design approach.


A system for controlling the pH of a formaldehyde-free aque ous binder composition used in the manufacture of glass fiber products. Following the formation of an aqueous binder com position, acid is added to the composition to reduce the pH to less than about 3.4. After the acid is combined with the aque ous binder composition, the pH of the composition is mea Sured and then compared within a pre-set set point. The rate of acid addition is then adjusted thereby adjusting the pH of the composition Such that the measured pH equals the set point pH. The pH measurement is preferably done before the addi tion of other additives to avoid interference by those addi tives.


This paper aimed to assess the use of biotherapics and isotherapics medicines in Curitiba. The pharmacies participants answered a questionnaire on their records and found the homeopathic prescriptions a year. The biotherapics and isotherapics represent less than 10% of all homeopathic prescriptions; Tuberculinum, Histaminum, Carcinosinum, Colibacilinum and Influenzinum were the most prescribed biotherapics and household dust, pollen and animal's hair were the most prescribed isotherapics; the liquid remedies were the most precribed; the Hahnemann's method was most widely


Based on a brief introduction of logistics and the development of regional economy,the paper analyzes the acting mechanism between west China's logistics and regional economy,analyzes the infuence factors of west China's logistics and west economy and brings forth the relevant strategies.


Masanobu NAKAMURA and Mitsuru TATE Synopsis: A mathematical model taking the flow and reactions in bath into consideration has been developed in order to investigate the decarburization process quantitatively. This model is able to simulate well the variation of process variables. The knowledges obtained from process analysis in this study are as follows: (i) the low value of oxygen efficiency for decarburization is due to the low value of absorption efficiency of oxygen, namely 50-60%, which is further caused by the relatively large resistance of mass transfer in gas phase; (ii) the fire spot occupies the area corresponding to the width of gas jet; (iii) the variation of exhaust gas composition is primarily determined by the division of unabsorbed oxygen between the combustion of CO gas and the oxidation of scattered droplets of liquid iron. Finally, the self-acceleration of decarburization in commercial converters has been pointed out.


Abstract In this article I report the findings of an intrinsic case study involving seven ecologically minded teachers who participated in a Critical Friends Group (CFG) for five months. The topic of our discussions was EcoJustice education, which involves analyzing and reframing Westernized culture. Findings are focused on how the participants grappled with what EcoJustice education means and their affective responses to both the content and the professional development experience. Analysis of the data revealed that reframing Westernized culture takes time, that it is not merely an intellectual exercise but also an emotional and psychological one, and that personal internalization comes before practical application. The participants also indicated that they valued being in a CFG where they could be honest and vulnerable as well as supported, connected, inspired, and challenged. I conclude by recommending CFGs as a model for transformative professional development in environmental education.


With the introduction of technology, which has been developed in line with the social needs, in almost every area of life, traditional agriculture has begun to lose its function. This new situation brings about the necessity of developing agricultural education programmes to be applied to the students at secondary education. For this reason, the agricultural education at each level from primary education to higher education should be reviewed and restructured in accordance with the needs of the modern age and take place more predominantly in the field of education which constitutes an important part of the improvement. The aim of this theoretical study is to explain the concept of literacy in agriculture, characteristics of agriculture literate individuals and providing recommendations for educating these people


: A molten salt reactor (MSR) is a class of nuclear fission reactors using a molten salt mixture as the primary coolant and fuel. As one of the generation IV reactors MSR has received an increasing attention. The corrosion of materials is one of the technical obstacles to the development of MSR, and thus has been investigated extensively. Up to now, great progresses have been achieved in the study of the corrosion of materials in MSR environments. This paper presents a comprehensive review of the research work on the materials corrosion in MSR.


When a country sees its sovereign credit risk rise, do companies in that country also see their credit risk increase? We show that the answer is yes. Companies with a large public-sector ownership, as well as companies that borrow heavily from banks, are most affected. This suggests that the transmission of credit risk from sovereigns to non-financial companies occurs primarily through a fiscal and a financial channel, and points to the importance of reducing such risk spillovers and thereby overall risk in the economy, e.g. by means of the capital markets union. JEL Classification: F34, F36, G15, H81, G12


To meet the new challenges of the chemical indutries, the developpement of new heterogeneous catalytic reactors and their understanding are mandatory. From these perspectives, new reactor designs based on structuring at micro or millimeter scales have emerged. They have sparked interest for their ability to decrease physical limitations for heat and mass transfers. Thus, two advanced reactor technologies for gas-liquid-solid catalysed reactions are studied. The first reactor is a micro-structured falling film (FFMR) in which vertical sub millimetric grooves are etched and coated with a catalyst. This structuration allows stabilizing the gas-liquid interface of a down flow liquid phase. A thin liquid film is generated leading to high specific surface areas. Commercially available, it represents a very good potential for performing demanding reactions (i.e.fast, exothermic) for small scale productions such as pharmaceuticals. In a second part, a new reactor concept is proposed. Open cell foams are used as catalyst support and inserted in a milli-square channel. The reactor is then submitted to a preformed gas-liquid Taylor flow. In both cases, hydrodynamics features are studied by using microscopy based methods. Their potential in terms of mass transfers are also studied by performing catalyzed α-methylstyren hydrogenation. For both reactors, it comes out that the particular flow induced by micro or milli structures leads to at least one order of magnitude higher mass transfers performances than mutliphase reactors currently used in the industry albeit it remains to be demonstrated at such scale. From all these studies, correlations, models and methods for chemical engineers (hydrodynamics, pressure drops, mass transfer) are proposed for the two reactors


This chapter is about how the memory of persecution decisively shaped 1970s homosexual politics. First, the chapter explores the 'rediscovery' of the Nazi persecution of homosexuals, explaining how the model of the Holocaust was sometimes appropriated as part of this process. The chapter then shows how memory of this persecution, combined with the experience of contemporary discrimination, produced a profound alienation on the part of left-wing gay men from the West German state. Following an analysis of how the pink triangle became a transnational symbol, this chapter evaluates discourses of victimhood in gay liberation. Though the pink triangle was reclaimed from its origins as a badge of shame in the concentration camps, it never became an unequivocal symbol of pride. Finally, the chapter explores how, in the late 1970s, activists of all stripes, the commercial gay press, and the first openly gay parliamentary candidates coalesced around making the history of past persecution a central plank in their efforts to insert themselves into the West German mainstream.


Extraction flavonoids from hemerocillis citrina baroni and then determination of flavonoids style by and chemical methods and TLC. Flavonoids was proved to be flavonol from these results.


The Revised Rokeach Value Survey was administered to 1319 Chinese undergraduates and middle school students. The result shows that the contemporary Chinese adolescent students consider home security, freedom, self esteem and national security as the most important ultimate values, and ambition, broad mindedness, competence and honesty as the most important instrumental values. The comparative study of the value outlook of Chinese adolescent students shows that in the past ten years there has been an increasing self oriented value outlook.


This study aims to determine the RADEC learning model's effectiveness in improving understanding of dynamic fluid material to XI students of Senior High School (SHS) in distance learning (distance learning). This study used a quasi-experimental method with a nonequivalent control group design. The research population was all students of XI SHS classes, totalling 154 people. The sampling technique used purposive sampling. The sample is XI-3 class as the control group and XI-4 class as the experimental group. The instrument used was a cognitive test. The data analysis technique used descriptive statistics and inferential statistics. The results showed that the two groups' average value is that the pre-test control group was 58.12, and the post-test was 78.13, while the pre-test and post-test experimental group were 76.72 and 87.19. Thus, it can be concluded that the RADEC learning model is more effective than the conventional learning model.


In this paper we present a Web-based system for annotating digitised old maps. Using bibliographic metadata and geographical reference information associated with the map, annotations are represented as spatially and temporally defined RDF resources. At the same time, named entity recognition and semantic link discovery are applied to each annotation's text content to further facilitate its interlinking within the Web of Data. To ensure quality and correctness, the system relies on human feedback. This feedback is introduced through a novel interaction metaphor: contextual link suggestions are continuously generated in the background, and superimposed on the annotated map region in the form of a tag cloud. The user can create semantic links by simply clicking on the corresponding tags. The system thus acts both as a visualisation aid for contextually relevant linked data and as a tool for authoring new linked spatiotemporal data entities.


Specific interventions included in the review Selected newer antidepressants (selective serotonin re-uptake inhibitors, serotonin and norepinephrine re-uptake inhibitors, norepinephrine re-uptake inhibitors, reversible inhibitors of monoamine oxidase A, 5-HT2 receptor antagonists, 5-HT1a receptor agonists, gamma-aminobutyric acid mimetics, dopamine re-uptake inhibitors), antagonists, herbal remedies (St. John's Wort) and older antidepressants (mixed serotonin and norepinephrine reuptake inhibitors, first-generation tricyclic antidepressants, second-generation tricyclic antidepressants, tetracyclic antidepressants, triazolopyridines, monoamine oxidase inhibitors) were investigated. All individual drugs are listed in the review article. Comparisons were made between any newer antidepressant and any other (newer or older) antidepressant, placebo, or psychosocial intervention. Studies of herbal remedies were also included.


Conclusions drawn from a series of questionnaires submitted to a national panel of chemistry department faculty regarding the nature of undergraduate chemistry.


Thirty-nine participants, 17 in a chronic steroid group (CS) and 22 in a steroid avoidance group (SA) were compared with regard to their cognitive performance. It was predicted that participants in the SA group would outperform those in the CS group on the domains of declarative memory and complex attention. For participants in the CS group, age and prednisone duration but not dose were predicted to significantly contribute to the score on the declarative memory composite score. Group-wise comparisons were not significant for the domains of declarative memory, complex attention, or processing speed. The CS group outperformed the SA group on the domain of simple attention. Regression analysis, for the CS group, indicated that duration of dialysis prior to transplant accounted for a significant portion of the variance in the declarative memory composite score. After controlling for months since transplant, prednisone dose also accounted for approximately 26% of the variance in the declarative memory score. Patients maintained on 5 mg of prednisone performed relatively worse than those maintained on 2.5 mg with regard to declarative memory. The clinical and theoretical significance of the findings relative to recent literature is discussed.


The report discusses the modernization of the linear electron accelerator MEA (Medium Energy Accelerator). The aim is to develop a set of MEA based free-electron lasers, imposed a number of emission wavelengths from infrared to ultraviolet. In work presents the results of the physical starting of the first accelerating station and status of work on the second accelerating station linear electron accelerator LINAC-800, as well as start the infrared undulator. We discuss the program of work of the accelerator.


Infrared absorption spectra have been observed in NTA and its metal chelates, in solid states as well as in solution. The results indicate that NTA does not exist as zwitter ions in the solid state, that it behaves as a quadridentate ligand for such divalent metals as copper, nickel, cobalt, zinc, cadmium and lead, but that it behaves as a terdentate ligand for the alkaline earth metals. It is also found that the wave number of the νC=O band of the coordinated carboxylate group in the NTA chelates tends to shift to a higher value with an increasing chelate stability constant.


In Response: We appreciate the comments of Drs Agarwal, Vishnu, and Srivastava. They also observed a reduction in overall stroke admissions but found an increase in the percentage of patients with hemorrhagic stroke. After the publishing of our article, coronavirus 2019 (COVID-19) continued to spread in Joinville. Until April 15, there were only 0.34 deaths per 100 000 inhabitants for COVID-19 in the city (a total of 2 cases). That number increased to 0.85 on May 1, 3.73 on June 1, 6.6 on July 1, and 22.86 on August 1 (135 cases). In our article, we reported an admission rate of 8.3 strokes per 100 000 inhabitants in the weeks following social restrictions, which started on March 17. In May, many social restrictions were lifted because of the low transmission rate of COVID-19 in the city. Also, an advertising campaign not to stay at home in case of stroke symptoms was conducted by an association of patients (Associação Brasil AVC). In the same month, we observed that the admission rate for stroke increased to 15.41, and in June it increased to 15.75. The admission rate decreased again in July, falling to 11.18 per 100 000 (a 15% reduction, when compared with July 2019). July was the month with most COVID19 cases to date, and we observed a peak of COVID-19 diagnosis at the end of the month. During that month, a series of restrictions were imposed in Joinville, such as the prohibition of public transportation, restrictions to restaurants, and limits to the operation of commerce. A reverse transcription polymerase chain reaction (RTPCR) or antibody test was requested in patients with stroke who had symptoms of COVID-19. Of all 64 strokes admitted to hospitals in July, 6 (9.1%) were also diagnosed with COVID-19. Contrary to what Agarwal et al1 report, we did not observe an increase in admissions for intraparenchymal hemorrhage. The average admission rate for intraparenchymal hemorrhage in 2019 was 6 cases per month in the city, ranging from 3 to 12. In April and May, we observed that 6 cases were admitted for intraparenchymal hemorrhage each month. In June, there were 7 cases, and 6 cases in July. From our experience, it seems that social distancing imposed by the government or self-imposed may play a role in reducing the admission rates for stroke. However, we did not observe an increase in admissions for intraparenchymal hemorrhage to date, as reported by other authors. We want to thank Drs Agarwal, Vishnu, and Srivastava for sharing their data, which are crucial to understanding the impacts of COVID-19 in stroke care.


This chapter investigates the extra Calvinisticum in the Reformed tradition after the shift to scholastic theology in the 1580s by investigating the work of French theologian Antoine de la Roche Chandieu. Chandieu is widely considered one of the fathers of Reformed scholasticism and produced the most extensive work on the extra in this period. In De Veritate Humanae Naturae Christi (1585) he offers an exposition and defense of the extra in response to the christology of Lutheran theologian Martin Chemnitz. Chandieu's work is distinguished from other treatments of the extra in both scope and depth, utilizing scholastic methodology, scriptural exegesis, and the church fathers. The work of Chandieu demonstrates the ongoing development of the extra in the period of early Reformed orthodoxy, which is in continuity with the precedent tradition and uses the new scholastic method not to unmoor it from the biblical witness but to secure it more firmly.


We were concerned to read that the paper in the March 2019 Issue of the Australian Dental Journal by Liaw et al1 made no reference to the need for all health professionals, including dentists, to be proactive in antibiotic stewardship. We are well into the post antibiotic age brought on by squandering the life saving benefits of antibiotics on non-bacterial or trivial uses.


This is an intensely personal book. It is a written record of the author's well-known style of presentation at lectures and meetings with cases. It reflects his great respect for biological data and his strong belief in oral tradition of valuable knowledge. He has followed some 200 cases of myeloma carefully during the last 30 years and tells us about them in an almost conversational manner. American readers may regret that such a vast experience has yielded relatively few crisp analyses in chart form and they may be uncomfortable with the seemingly casual writing, which makes it difficult to look up specific points. However, this book is primarily directed to hematologists who will want to read through the entire text and will be richly rewarded by Waldenstrom's perspective and his many "pearls," eg, (1) high percentage of plasma cells means poor prognosis; none of his patients with more than 30%


A model was developed to design the acoustics of a classroom and reduce the background noise level. The design allowed the reverberation time to be limited, and was based on estimation of design parameters. The maximum sound power level emitted by heating ventilation and air conditioning designs (HVAC) were calculated for the design. The formulation and validation of the model was described.


Plant G protein γ subunits have multiple functions in growth and development processes and in abiotic stress responses. Few functions of Gγ in horticultural crops have been revealed thus far. In this study, the potential function of CsGG3.1-2, one of the two alternative splice variants of Gγ gene CsGG3.1 in cucumber (Cucumis sativus L.), was investigated using transgenic plants overexpressing antisense CsGG3.1-2 under the control of the 35S promoter. The tolerance to chilling stress in transgenic plants was significantly decreased. Cold stress-related physiological parameters and the expression of CBFs and their downstream target genes were then measured. Compared with WT, the maximum efficiency of photosystem II (Fv/Fm), antioxidative enzymes activities, soluble protein, and proline accumulation decreased significantly in transgenic plants treated with cold stress, whereas the malonaldehyde (MDA) content increased. However, the overexpression of antisense CsGG3.1-2 did not affect the induction of cold-inducible genes. Quantitative real-time PCR (qPCR) analysis showed the increased expression of CBF genes and their downstream target genes in transgenic plants, suggesting that CsGG3.1-2 affects cold responses via CBF-independent pathways in cucumber. At the same time, the sucrose and fructose contents decreased in transgenic plants under both normal and cold conditions. These findings suggest that soluble sugar deficiency is associated with chilling sensitivity in transgenic plants, and CsGG3.1-2 may have a role in regulating carbohydrate metabolism in cucumber.


The most important role of the strategy of socio-economic development of the region places high demands on the quality of its. One of the mechanisms for quality control of the development of any plan, including strategic, is the evaluation of its effectiveness, carried out on the basis of implementation. However, with regard to regional strategies, the current legislation (the Federal law "On strategic planning in the Russian Federation") obliges only to assess the achievement of socio-economic development goals. Five years' experience in the development of regional strategies accumulated for the period of validity of the act allowed us to set a goal to generalize this experience in terms of compliance with the assessment of thestrategies' objectives achievement. The practical basis of the study was all regional strategies of socio-economic development, both existing and terminated (a total of 128), available at the time of writing this paper. We tested the strategies as per the existence and content of the assessment of the achievement of the socio-economic development goals of the region. According to the study, the assessment of the achievement of socio-economic development goals is carried out formally, and in most cases – is not carried out at all. Therefore, the author concludes that it is necessary to strengthen the attention of strategic planning participants to this issue. The article also raises the question of the need for regulatory and methodological backing of the assessment of the effectiveness of regional strategies of socio-economic development as a tool to improve the quality of strategy development and, as a consequence, the growth of the effectiveness of regional strategic planning. The reason for this conclusion is the presence of this mechanism in the evaluation of the implementation of state programs – planning documents lower than the strategy level, but based on the same as the strategy, methodological prerequisites.


A new species, Coenosia ungulipardus sp.nov., is described and illustrated from Sichuan Province, China. A new group C.ungulipardus-group is proposed, the main characters of which are as follows:frontal triangle of male extending to middle of frons; without outer vertical bristle; antenna normal; lower squama short and small, dc 1+3; legs black, t-3 with 2 ad; cerci and surstyli slender, epiphallus evident. The type specimen is deposited in Shenyang Normal College.


The new business-rescue regime is set to change the corporate landscape significantly. It is intended to achieve a better outcome for all creditors by re-balancing certain rights (for example the right to call up security) in the hope that either the business in question can be saved or that a greater dividend can be achieved on liquidation. This article discusses the reasons for the introduction of the business-rescue regime, and deals briefly with the workings of a business rescue.


: The Discrete Cosine Transform (DCT) is a basic transform block used in Adaptive Multicore Transform (AMT), which is a core of High Efficiency Video Coding (HEVC) and Versatile Video Coding (VVC) standards. AMT uses artificial intelligence technique to decide on the transform output. The suggested One-Dimensional DCT architecture is conceived by 8-point structure Loeffler-DCT technique and synthesized using a floating-point Arithmetic. By preserving the structural regularity as the Loeffler-based design, the optimized floating-point architecture consumes optimum space and delay thereby increasing the precision. The work focuses on obtaining high precision output without compromising on ADP (Area-Delay-Product). Due to the fact that the floating-point multiplier unit is developed using shift-add operations, the results reveal the accomplishment of better resolution output while maintaining Root Mean Square deviation as low as 0.0062. A total of 117 additions, 66 shifts are employed in the suggested architecture. The proposed 1D-DCT is used as a sub-block in developing the architecture of 2D-DCT using only 50% of the 1D-DCT subblocks that is needed for the conventional technique. The 8 X 8 2-D DCT, is computed using only 8 1-D DCT's and additions, instead of using 16 1-D DCT's, as in the traditional row-column method. The model is tested with standard images, which resulted in better PSNR and MSE compared to the standard method. In comparison to the state-of-the-art on DCT, the proposed method obtains a root mean square error that is negligible up to three decimal places resulting in improvement of PSNR by 17%, with a maximum clock frequency of 496MHz has been achieved. The proposed design strikes a balance between trade-off parameters such as area, speed, and precision.


A new fully differential CMOS dynamic comparator topology suitable for pipeline A/D converters with a low stage resolution is proposed. A thorough analysis of its function and a comparison to a widely used dynamic comparator are given in this paper. The proposed topology, based on two cross coupled differential pairs and switchable current sources, has a small power and area dissipation and it is shown to be very robust against transistor mismatch.


OBJECTIVE:  To investigate whether RNA interference (RNAi) of the ubiquitin fusion‐degradation 1‐like protein (Ufd1) could sensitize hydroxycamptothecin (HCPT)‐resistant colon cancer cell line SW1116/HCPT to the cytotoxic effect of HCPT.


London South Bank University (LSBU) is a public university in Newington, London, founded in 1892 as the Borough Polytechnic Institute. Illustrated and containing an introduction by Sidney Webb.


Metallic multilayer films consisting of ferromagnetic PtMnSb and antiferromagnetic CuMnSb were prepared by an rf sputtering method. From the x‐ray diffraction data, all the films were found to have a [111] texture of the C1b ‐type Heusler structure. The magnetization measured in PtMnSb/CuMnSb multilayers was larger than that in a PtMnSb compound. The temperature dependence of magnetization shows a bend at about 50 K near the Neel temperature of CuMnSb. This bend is explained qualitatively by using a molecular field model and assuming a trapezoidal modulation of exchange interaction.


We consider a class of differential games with transition equations that are homogeneous of degree one. For any game G with a discount rate r, consider a Markov perfect equilibrium (MPE) with strategies that are linear in the state variables. We show that the time paths of the control variables of this equilibrium constitute an open-loop equilibrium of a corresponding game Classification-JEL: C72; C73; Q30


We haven't already completely solve the problem about steel bridge deck pavement by studying the steel bridge deck pavement structure layer and pavement material.On the basis of theoretical analysis,this experiment proposes a new method that Painting SR reflection heat insulation coating on the bottom plate and web of steel bridge would reduce the temperature of the steel bridge pavement system.


In a report by Clarivate Analytics for the Brazilian Coordination for the Improvement of Higher-Level-Education Personnel (CAPES) about the Brazilian research productivity between 2013 and 2018, Brazil ranked 13th (250 680 publications) among countries with the highest research productivity, corresponding to 11% and 16% of the first ranked countries, United States and China, respectively., In that period, the publications in Brazil increased by 30%, twice the global mean, with over 50 000 articles published in 2018 only. A good example [...]


The paper explores the factors affecting the satisfaction degree of customers of food and beverage enterprise and the difference space between perception and apperception,and based on the investigation,it analyses the tendence and marketing tactics of the food and beverage industry.


Electronic Design Contest has a great influence on higher education and even the entire society.The students and docents have yielded good results from this.Electronic Design Contest promotes the Educational reform for Electronic Information Engineering of Vocational Education,and provides the effective feedbacks and ideas for the education reform in curriculum and teaching methods.


We consider observations $(X,y)$ from single index models with unknown link function, Gaussian covariates and a regularized M-estimator $\hat\beta$ constructed from convex loss function and regularizer. In the regime where sample size $n$ and dimension $p$ are both increasing such that $p/n$ has a finite limit, the behavior of the empirical distribution of $\hat\beta$ and the predicted values $X\hat\beta$ has been previously characterized in a number of models: The empirical distributions are known to converge to proximal operators of the loss and penalty in a related Gaussian sequence model, which captures the interplay between ratio $p/n$, loss, regularization and the data generating process. This connection between$(\hat\beta,X\hat\beta)$ and the corresponding proximal operators require solving fixed-point equations that typically involve unobservable quantities such as the prior distribution on the index or the link function. This paper develops a different theory to describe the empirical distribution of $\hat\beta$ and $X\hat\beta$: Approximations of $(\hat\beta,X\hat\beta)$ in terms of proximal operators are provided that only involve observable adjustments. These proposed observable adjustments are data-driven, e.g., do not require prior knowledge of the index or the link function. These new adjustments yield confidence intervals for individual components of the index, as well as estimators of the correlation of $\hat\beta$ with the index. The interplay between loss, regularization and the model is thus captured in a data-driven manner, without solving the fixed-point equations studied in previous works. The results apply to both strongly convex regularizers and unregularized M-estimation. Simulations are provided for the square and logistic loss in single index models including logistic regression and 1-bit compressed sensing with 20\% corrupted bits.


Just as the tepid bath was used in cases of dementia so in cases of rheumatism the bath of medium temperature in the range of 98°-100° F. (370-380 C.) will give the patient more relief from muscle spasm in the simplest way. The water, in addition to its sedative thermal -effect, acts as a buffer or body insulator and the more buoyant the water the more easily is a disorganized limb moved in the bath.


In the title compound, C12H11ClFN3, the benzene ring forms a dihedral angle of 72.43 (5)° with the pyrimidine ring. In the crystal, N—H⋯N hydrogen bonds link the molecules into a chain running along the c axis.


Survivin, a novel member of the inhibitor of apoptosis protein (IAP) family, is found to be expressed by a majority of human cancers but not in adult normal tissues[1]. Anticancer therapy targeting survivin has drawn considerable attention. It is a 16.5 kDa protein, which consisted of two defined domains including an N-terminal Zn2+-binding baculovirus IAP repeat (BIR) domain linked to an amphipathic C-terminal α-helix[2]. Survivin, which is situated on chromosome 17q25, is an unique bifunctional protein that inhibited apoptosis by suppressing caspase-3 and caspase-7, and modulating the G2/M phase of the cell cycle by associating with the mitotic spindle microtubules[3]. However, Thr34→Ala mutant survivin (T34A) was found to show anticancer properties in gene therapy, which is related to the loss of Thr34 phosphorylation[4]. Considering the safety of gene therapy, an anticancer protein drug targeting survivin, TATm-survivin (T34A), was reported by Ma[5,6]. TATm-survivin (T34A) is a HIV-TAT-fusion protein that contained N-terminal protein transduction domain (PTD) for the delivery of this drug into cancer cells. It was expressed highly as inclusion bodies in Escherichia coli BL21 (DE3) under the control of T7 promoter and displayed the pro-apoptotic bioactivity against various cancer cells[5,6].


Based on description and analysis of the distribution of the years and Chinese periodicals about the articles on leisure sports from 1994-2008,the author has found that the studies on the leisure sports have escalated steadily,and fundamentally come into being the hot topic,but the studies have not been the focus.And two most important journals are Journal of Guangzhou Sport University and Journal of Sport History and Culture.The author has compared and analyzed the definition and type of leisure sports which are the essential questions in the realm of leisure sports,and defined and classified the leisure sports according to the leisure time and inner experience,thereby cleared up the connotation and extension in order to promote the development of studies on leisure sports in the depth.


Results from a finite-difference Navier-Stokes code for three-dimensional, unsteady, vortical flows in unbounded domains are presented and analyzed in this paper. The vortical flows presented are representative of vortex rings and other closed vortical tubes or structures in fluid mechanics. Such structures are important elements in fluid flows such as jets, atmospheric turbulence, and the far-field wakes of aircraft, and studies of their interaction may aid in an understanding of complex fluid flows. The paper demonstrates that computational methods can be used as a viable alternative or supplement to experimental techniques for studying the physics of vortex flows. The separate visualization of vortex stretching, convection, and diffusion is presented in this paper for a single elliptical vortex ring.The calculations employ a truncated series expansion technique to simulate the unbounded nature of the fluid flow with a finite computational domain, which is a more accurate technique than the conventional freestream boundary specification. The numerical divergence of the three-dimensional vorticity field is considered as a useful estimate of truncation error, and the use of a kinetic energy decay law as a calculation check is demonstrated. Results from the Navier-Stokes code are presented for the unsteady motion of two and four vortex rings along parallel axes, and the results agree qualitatively with experimental flow visualization.


In the ice-laden polar oceans, water temperatures of — 2 °C are common. This temperature is 1.1 °C below the equilibrium freezing point ( — 0.9 °C) of the fishes' body fluids. Avoidance of freezing in these environments has been linked to the presence of unusual blood peptides and glycopeptides. These molecules have molecular masses ranging from 2.5 to 20 kDa and are viewed as having antifreeze properties because they lower the freezing point of water by a non-colligative process. A 2 % solution of antifreeze has a freezing point of — 1.2 °C and ice formed in their presence melts at —0.02 °C. Measurements of antifreeze concentrations in ice indicate that these molecules, unlike other proteins ofsimilar size and conformation, are incorporated into the solid phase during freezing and adsorb to it. Adsorption of the antifreezes to ice appears to inhibit growth along the preferred axes (a-axes) by raising the curvature of the growth steps on the basal plane. At temperatures below —1.2 °C, crystal growth occurs in the form of long spicules whose axes are parallel to the c-axis, the non-preferred axis of growth.


Summary form only given. We demonstrate the application of a variable-coherence laser source for determining the scattering parameters of a diffuse medium and the potential for imaging spatially-dependent scatter. A key concept in this work in the ability to synthesize a variable-coherence source by frequency modulating a tunable laser diode (with a center wavelength of 850 nm) at a rate much faster than the integration time of the detector. This allows for a rapid measurement and the adaption of laser coherence to the degree of scatter, which we show is critical in obtaining the necessary sensitivity.


The Open Archives Initiative - Object Reuse and Exchange (OAI-ORE) specifications provide a flexible set of mechanisms for transferring complex data objects between different systems. In order to serve as an exchange syntax, OAI-ORE must be able to support the import of information from localized data structures serving various communities of practice. In this paper, we examine the Metadata Encoding & Transmission Standard (METS) and the issues that arise when trying to map from a localized structural metadata schema into the OAI-ORE data model and serialization syntaxes.


The influences of heat treatment parameters on mechanical properties of large diameter bearing ring of 9Cr18 strainless steel are investigated,and the distortion controlling methods of the large diameter and thin wall bearing rings are discussed.The results show that after quenching,cold treatment and tempered at low temperature,the mechanical properties of the large diamater bearing ring of 9Cr18 strainless steel meet the technique requirements.The optimized heat treatment process of the rings is that after quenched at 1 060 ℃ and cold treatment at-70 ℃,the bearing ring is tempered at 160 ℃.


OBJECTIVE
To investigate the secular trend of infection rate, risk factor exposure rates for nosocomial pneumonia (NP), and to evaluate the nosocomial infection surveillance and control programs efficacy in an university hospital from 1993 to 2000.

METHODS
All 126 665 hospitalized patients from 1993 to 2000 were studied for NP. The independent risk factors for NP were analyzed by using case-control study method and logistic regression technique. The time-specific rates for NP and risk factor exposure were calculated annually.

RESULTS
The infection rates for NP were decreased by 50% from 1.20% in 1993 to 0.60% in 2000. The logistic regression analysis showed that the independent risk factors for NP were immunosuppressive therapy (OR = 2.72), chemotherapy (OR = 2.17), cancer (OR = 1.45), chronic obstructive pulmonary disease (COPD, OR = 1.88), ICU (OR = 3.18), coma (OR = 3.26), tracheotomy (OR = 14.95), hemodialysis (OR = 5.12), bone or lumbar puncture (OR = 1.82). The time-trends for exposure rates of COPD and bone or lumbar puncture were slightly decreased, however those for the others and the synthetic risk factors were not changed significantly.

CONCLUSION
The infection rates for NP were significantly decreased in the case of no change for exposure rates of risk factors for NP, this suggests that the nosocomial infection surveillance and control programs were effective for lowering infection rate for NP in this hospital.


A numerical material model for intra-laminar failure prediction of biaxial Non Crimp Fabric composites is presented. The model combines the elasto-plastic continuum damage constitutive model proposed by Ladevèze with the intra-laminar matrix failure model of Puck, and improves the shear damage representation using an exponential damage function. The work focuses on numerical model development for damage and failure prediction and validation for both unsheared and sheared fabric composites which will result from draping of the fabric preform over a double curved geometry in order to manufacture complex shaped parts. An extensive test program has been conducted using flat composite coupons with differing degrees of fabric pre-shear in order to establish a database of material stiffness, strength, and in-plane matrix shear damage evolution prior to failure. This database is used to identify parameters for the proposed 'Ladevèze-Puck' damage and failure model. Final validation has been made by implementing the model in an explicit Finite Element code and performing a series of experimental and simulation analyses on transversely loaded circular composite discs having differing degrees of fabric pre-shear.


The thermal dependence of sprint speed, exertion distance and time, and aggressive response was examined in the island night lizard, Xantusia riuersiana, over a body temperature range of 10-35 C. Critical thermal limits were 6.6 and 39.0 C. Thermal optima for sprint speed and distance approximated preferred body temperature (28.3 C) and declined at higher or lower body temperatures. Exertion time was largely independent of body temperature, and lizards ran for about 70-90 s. Speed during exertion sprinting declined exponentially with increasing time and distance covered. Maximum oxygen consumption at 30 C (V,,,,,) occurred immediately following burst sprinting and was greater than values recorded for other species of lizards of similar body mass; factorial aerobic scope relative to standard V,, was 29. Maximal aggressive responses occurred at low body temperatures which are suboptimal for sprinting, but aggressive behavior was always preceded by a sprint to exhaustion. Temperature and exercise state appear to be interacting factors influencing aggressive responses. Xantusia riversiana is a diurnal but reclusive lizard with relatively low preferred body temper- ature and low temperature optimum for sprinting. In the dense vegetative scrub and rocks that the lizards inhabit, sprint escape from predators is the initial response at all activity body temper- atures. Sprint performance also represents capacity for struggle against restraint, and the increased aggressive response of exhausted lizards at low body temperatures may be a defensive response compensating diminished capacity for struggle at low body temperatures.


Listening  Mr and Mrs Jones are in the kitchen. Listen and tick what Mrs Jones wants for breakfast today.  tomatoes  mushrooms  bacon  sausages  eggs  tea  coffee  chocolate  orange juice  milk  baked beans  toast  jam  sugar  cereal  butter  honey  cheese  biscuits  fruit Writing  What do you usually have for breakfast? (Décris ton petit déjeuner habituel à l'aide des mots ci-dessous  For breakfast I have... , ... , ... and ...)


Experimental results on the $$\Sigma^+(1189)$$ hyperon transverse polarization in photoproduction on a hydrogen target using the CLAS detector at Jefferson laboratory are presented. The $$\Sigma^+(1189)$$ was reconstructed in the exclusive reaction $$\gamma+p\rightarrow K^{0}_{S} + \Sigma^+(1189)$$ via the $$\Sigma^{+} \to p \pi^{0}$$ decay mode. The $$K^{0}_S$$ was reconstructed in the invariant mass of two oppositely charged pions with the $$\pi^0$$ identified in the missing mass of the detected $$p\pi^+\pi^-$$ final state. Experimental data were collected in the photon energy range $$E_{\gamma}$$ = 1.0-3.5 GeV ($$\sqrt{s}$$ range 1.66-2.73 GeV). We observe a large negative polarization of up to 95%. As the mechanism of transverse polarization of hyperons produced in unpolarized photoproduction experiments is still not well understood, these results will help to distinguish between different theoretical models on hyperon production and provide valuable information for the searches of missing baryon resonances.


In the fall of 2008,the cowpea growing in a greenhouse in Shanghai suburban suffered a disease characterized by chlorotic and yellowing leaves.The complete nucleotide sequence of a tomato yellow leaf curl virus was amplified from DNA extracted from diseased plants.The sequence comparisons and phylogenetic analysis revealed that the pathogen was Tomato yellow leaf curl virus-Israel(TYLCV-IL),a member of the genus Begomovirus.The genome consisted of circular ssDNA with 2781 nucleotides,which has the typical characteristic of Old World monopartite begomoviruses with six ORFs corresponding to V2 and V1(Capsid Protein gene)on the viral strand,and C3,C2,C1 and C4 on the complementary strand.This is the first report that a natural Tomato yellow leaf curl virus infected V.sinensis.


In order to get a better understanding of the effects of cleaning and restoring treatments applied on stained glass windows, systematic characterisations of treated objects have beeen performed by electron microscopy (scanning - SEM - and transmission - TEM). Researches have been focused on the ageing of applied products on the effects of supercritical drying, and on the characterisation of materials after cleaning and application of restoring (SZA) and conservation (Ormocer) products. Different treatments have been tested on samples from the Saint-Gatien cathedral of Tours and on model glasses which were references for several teams. Tests have been also performed on stained glass windows of Saint-Opportune du Bosc church (Evreux). Results allow to compare the different chemical cleanings and to characterise the layers of SZA AND Ormocer. Supercritical drying favours a better penetration of SZA, but its use is not recommended between the application of SZA and Ormocer because densification and dehydratation of the restored layer occured and then the adherence between SZA and Ormocer is not efficient.


ABSTRACT Cryptococcus neoformans var. neoformans(serotype D) and C. neoformans var. grubii(serotype A) differ in geographic prevalence and dermatotropism, withC. neoformans var. neoformans strains being more prevalent among isolates from temperate countries as well as from skin infections. Analysis of 19 strains from each serotype revealed wide variation in thermal susceptibility, with C. neoformans var. neoformans strains being more susceptible, on average, to heat killing. The results suggest a consistent explanation for the geographic differences between serotype A and D strains and for the dermatotropism of serotype D strains.


The invention discloses a method for determining a cooling temperature of carbon paste of a graphite electrode. The method is characterized by comprising the following steps: testing a power viscosity index of the rheology property of coal tar pitch serving as the carbon paste binder, establishing a mathematic model experience formula of the cooling temperature t of the carbon paste of the graphite electrode, and determining an upper limit range and a lower limit range of the cooling temperature t of the carbon paste of the graphite electrode by using a mathematic calculation method. With the adoption of the method, two mathematic model experience formulae which can be used synchronously or separately are provided, so the method is scientific and reasonable; the cooling temperature t of the carbon paste of the graphite electrode can be determined easily and accurately; the cooling temperature t of the carbon paste can be calculated accurately according to the rheology property of the coal tar pitch, and thus the method has the advantages of a small number of pilot production profiling products, low rejection rate of green-pressing, high production efficiency of profiling procedure and stable green-pressing quality of graphite electrodes and the like, and the pilot production and regulation period of the profiling procedure are shortened, and the production cost of carbon enterprises is reduced.


In this paper, we propose an emotion recognition
system from speech signal using both spectral and
prosodic features. Most traditional systems have focused
on spectral features or prosodic features. Since both the
spectral and the prosodic features contain emotion
information, it is believed that combining spectral features
and prosodic features will improve the performance of the
emotion recognition system. Therefore, we propose to use
both spectral and prosodic features. For spectral features,
a GMM super vector based SVM is applied. For prosodic
features, a set of prosodic features that are clearly
correlated with speech emotional states and SVM is also
used for emotion recognition. The combination of both
spectral features and prosodic features is done and an
SVM is trained using the combined feature vector. The
emotion recognition accuracy of our experiments allow us
to explain which features carry the most emotional
information and why. It also allows us to develop criteria
to class emotions together. Using these techniques we
achieved high emotion recognition accuracy


Background N6-methyladenosine (m6A) RNA methylation is the most common chemical decoration in mammalian RNAs which exerts vital effects on numerous cellular processes. Recently, m6A regulators have been validated to participate in promoting immune evasion and act as prognostic factors in various cancers. Nevertheless, the predictive abilities of m6A regulators for the prognosis and immunotherapy response in gastric cancer (GC) remain indistinct. Methods Herein, The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx) database, The Human Protein Atlas (HPA), and a clinical GC cohort were applied for differential expression analysis, correlation analysis, survival analysis, and hazard model construction. Consensus clustering analysis was performed to authenticate the PD-L1 (CD274) expression, stemness features, immune cell infiltration, and tumor microenvironment (TME) in GC individuals. Furthermore, protein-protein interaction, immunotherapy response prediction, and drug susceptibility prediction were performed, respectively. Additionally, tissue microarray (TMA), immunohistochemical staining, western blot assay, Transwell assay, and flow cytometry assay were adopted to evaluate the protein expression, the prognostic value, and the influence of FTO on GC malignant phenotypes as well as the expression of PD-L1. Results In agreement with the majority of m6A regulators, FTO was overexpressed and predicted poor prognosis in GC. Based on consensus clustering analysis, two independent subgroups (G1/G2) were identified. Notably, FTO was upregulated in the G1 subgroup. Meanwhile, the infiltration level of CD8+ T cells was strikingly decreased while the stemness features were enhanced in the G1 subgroup. More importantly, FTO was negatively correlated with microsatellite instability (MSI) and tumor mutation burden (TMB). Furthermore, immune checkpoint blockade (ICB) response prediction indicated that patients with upregulated FTO showed high tumor immune dysfunction and exclusion (TIDE) scores. Subsequently, FTO was confirmed to be related to multiple immune checkpoints, particularly PD-L1. Specifically, FTO was dramatically upregulated in GC cell lines and clinical cancer samples. Functional experiments illustrated that FTO acted as an oncogene to facilitate malignant phenotypes. Notably, PD-L1 was remarkably downregulated after RNA interference-mediated knockdown of FTO. Conclusion FTO can aggravate GC malignant phenotypes. More importantly, it could be utilized to predict the long-term prognosis and the immunotherapy response in GC individuals. However, larger trials should be performed to verify the prediction accuracy.


For many people, a good game is synonymous with good graphics. One thing that is often forgotten, is that the graphics only makes up one part of the games. An aspect of the games that is far to often forgotten, is the game's content and ability to tell stories. Through analyses of the games of the Zelda series, the development of content and storytelling aspects of computer- and video games, since the later half of the 1980:s and up till today, are examined.


ABSTRACT Controlling individuals' salt intakes from discretionary sources is one of Portugal's public health priority, to reduce factors risks for cardiometabolic diseases. Starter soups, turnip green (TG), Carrot (C) and Carrot with cabbage (CC), from a Portuguese university canteen, were evaluated by sodium content varying in salt addition, the usual amount of salt (R0); with 25% (R25), and 35% (R35) of salt reduction, respectively. One hundred and seven students participated in the research during lunchtime. Check-all-that-apply (CATA) was applied, as well as the acceptability and saltiness perception. There were no differences (p > 0.05) for acceptability and saltiness perception of TG and CC soups with different amounts of salt, but reduced salt samples of carrot soup were perceived to be saltier and overall more liked compared to its usual recipe. This data suggests that 35% of salt reduction is possible in complex matrices as Portuguese starter soups without a loss of acceptance by consumers.


Co-training is a popular semi-supervised learning method. The learners exchange pseudo-labels obtained from different views to reduce the accumulation of errors. One of the key issues is how to ensure the quality of pseudo-labels. However, the pseudo-labels obtained during the co-training process may be inaccurate. In this paper, we propose a safe co-training (SaCo) algorithm for regression with two new characteristics. First, the safe labeling technique obtains pseudo-labels that are certified by both views to ensure their reliability. It differs from popular techniques of using two views to assign pseudo-labels to each other. Second, the label dynamic adjustment strategy updates the previous pseudo-labels to keep them up-to-date. These pseudo-labels are predicted using the augmented training data. Experiments are conducted on twelve datasets commonly used for regression testing. Results show that SaCo is superior to other co-training style regression algorithms and state-of-the-art semi-supervised regression algorithms.


In this paper, a group acceptance sampling plan for a truncated life test is proposed when a multiple number of items as a group can be tested simultaneously in a tester, assuming that the lifetime of a product follows the Weibull distribution with a known shape parameter. The design parameters such as the number of groups and the acceptance number will be determined by satisfying the producer's and the consumer's risks at the specified quality levels, while the termination time and the number of testers are specified. The results are explained with tables and examples.


Bare land is common on hillsides and may occur due to landslides, cultivated lands, or engineering construction sites. The purpose of this study is to analyze the visual preference of treatment of bare land on hillside. The treatment methods for bare land are classified into ecological engineering, non-ecological engineering, and natural recovery or vegetation. For this study, first, several images of areas in North Taiwan that experienced landslides or engineering construction were collected, including Daan and Shilin districts in Taipei city, Wugu, Shiding and Tamsui districts in New Taipei city, and Fuxing district in Taoyuan city. Then, Photoshop software was used for image processing and for calculation of percentage of vegetation cover on the bare land, i.e., the green looking ratio (GR). Furthermore, a questionnaire survey was conducted to investigate the visual preference (P) and the cognitive factor of an image associated with the GR. Three cognitive factors, consistency (C), vividness (V), and naturalness (N), were used for the survey. A total of 131 effective questionnaires were received from survey respondents and the Likert scale was used to rate the degree of visual preference and cognition. The rating values ranged from 1 to 5. The results show that a higher N, V, and C was preferred by viewers when the bare land was covered with vegetation or high GR. The factors C, V, N, and P for treatment of bare land using ecological engineering method are higher than those using non-ecological engineering. The adopted natural or flexible methods to treat bare land prompt visual preferences from viewers and can provide important references for landscape engineering design.


Background: Chronic obstructive pulmonary disease (COPD) is currently the fourth leading cause of death in the United States. Patients with COPD experience systemic inflammation that can be evaluated by measuring the levels of Creactive protein (CRP). Recently, the development of a high-sensitivity (HS) CRP test has made it possible to assess low grades of inflammation. Because there is systemic, as well as local, inflammation in COPD patients and because the disease cannot be staged by spirometry alone. Objectives: We evaluated the usefulness of HSCRP values as a readily available and cost-effective auxiliary marker for determining COPD stages in a group of COPD patients. Patients and Methods: A cross-sectional study was conducted in 160 COPD patients who were admitted due to exacerbations of their condition to Razi Hospital in Rasht, Iran. The patients' demographic characteristics, pulmonary function tests, and laboratory results of arterial blood gases and HSCRP levels were analyzed using SPSS 16 software. Results: A significantly positive correlation was found between serum HSCRP levels and the stage of the disease (as defined by the criteria of the Global Initiative for Chronic Obstructive Lung Disease). There was a significant relationship between HSCRP levels and the patients' sex, body mass index (BMI), and smoking history. Specifically, males and smokers had higher HSCRP values, and patients with normal BMIs had lower HSCRP levels. Patients with higher pCO2 values also showed higher levels of serum CRP. Conclusions: This survey supports the role of HSCRP as a simple auxiliary marker that can be used to stage COPD and determine patient prognosis and early management.


Background: Stenotrophomonas maltophilia ( S. maltophilia ) bacteremia in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients is associated with significant morbidity and mortality rate. Although several predisposing risk factors for S. maltophilia bacteremia following allo-HSCT have been identified, there is no agreement or consistency among clinical factors on whether to predict treatment outcome or not. Methods: From January 2005 to December 2014, data on demographic and clinical characteristics, treatment and outcome were collected for all S. maltophilia bacteremia cases observed at an 800-bed tertiary care hospital with a 32-bed transplantation ward. They were analyzed with respect to incidence and 90-day mortality. The risk factors associated with 90-day mortality of allo-HSCT recipients with S. maltophilia bacteremia were also analyzed by Log-rank test according to age, sex, neutropenia, platelet, C-reactive protein (CRP), albumin, creatinine, engraftment, graft-versus-host disease, primary disease risk, severe sepsis or septic shock, complicated infection, and conditioning intensity. Significant variables in the univariate analysis were included in the multivariate Cox proportional-hazards regression model. Results: A total of 65 patients (47 patients in allo-HSCT recipients and 18 patients in non allo-HSCT recipients) with S. maltophilia bacteremia were identified, with the incidence of 1.17 cases per 100 admissions and 0.35 cases per 1000 patient-days. The incidence was significantly high in allo-HSCT recipients compared to non allo-HSCT recipients (6.53 vs 0.36 per 100 admission, p vs 0.63 per 100 admission, p In multivariate analysis, the independent risk factors associated with 90-day mortality of allo-HSCT recipients were a high CRP level (>=10.0 mg/dl) (adjusted hazard ratio [aHR], 4.43; 95% confidence interval [CI], 1.55-12.63; p p p =0.001). Among nine patients with high CRP and low albumin level, five of them had pneumonia at the onset of bacteremia and the others developed pneumonia under effective treatment in median three-days. Conclusion: The incidence of S. maltophilia bacteremia was increasing during the last 5 years and 90-day mortality was high in allo-HSCT setting compared to non allo-HSCT setting. Higher CRP value or lower albumin level as a result of more complicated infection may predict poor prognosis of patients with S. maltophilia bacteremia. Disclosures No relevant conflicts of interest to declare.


Group aspects are essential to the success of software projects; however, almost no research regarding group maturity in CMMI‐DEV Level 5 organizations has been conducted. The objective of this work is to investigate group maturity and its relationship to the efficiency and effectiveness of Agile Software Development teams in a CMMI‐DEV Level 5 organization. A case study was conducted, and three data collection methods were used: a validated questionnaire was given to nine agile software teams (59 people) to measure specific aspects of group maturity, team efficiency, and team effectiveness; the effort to develop Use Case Points and a group rate (related to productivity and salary) were collected to investigate team efficiency, and focus group sessions and semi‐structured interviews were conducted with project managers and team leaders to explore group issues in software development. Aspects of group maturity were correlated with team effectiveness and team efficiency measures. Communication was found to be strongly correlated with team effectiveness and group rate, and conformity and the clarity of roles and goals were found to be strongly correlated with team efficiency. The results suggest that group maturity has a positive influence on software teams in CMMI‐DEV Level 5 organizations.


This study aims to determine: (1) the effect of learning motivation on student achievement upscale, (2) the effect of tutoring parents on learning achievement upscale, and (3) the effect of learning motivation and tutoring parents on learning achievement upscale. This research uses quantitative research and research design Ex-Posfacto. The object of this study is upscale students (IV and V) which total number is 218 students of SD Muhammadiyah 16 Karangasem. A sample of 59 students by using proportionate stratified random sampling technique. The data analysis method is multiple regression. The results of this study indicate that: (1) there is learning motivation on learning achievement upscale in SD Muhammadiyah 16 Karangasem in 2015/2016 to obtain tcount 2,677> 2,002 ttable, and the effective contribution is 18,3458%. (2) there is tutoring parents on student achievement upscale SD Muhammadiyah 16 Karangasem in 2015/2016 to obtain tcount 2,758 > 2,002 ttable, and the effective contribution is 19,0784%. (3) there is motivation to learn and tutoring parents together on student achievement upscale SD Muhammadiyah 16 Karangasem in 2015/2016 to obtain the value of Fcount 16,744 > F table 3.15, the effective contribution of learning motivation and tutoring parents together on learning achievement is 37,4% and the remaining 62,6% is influenced by other factors. Based on the results of this study,it can be concluded that there are the effect significant of learning motivation and tutoring parents on learning achievement upscale in SD Muhammadiyah 16 Karangasem in 2015/2016.


The variation in the forms of treatment of the second person speech gives rise to several discussions (still) today. With the knowledge of the theoretical bases that support the view of the ecology of communicative interaction (COUTO, 2014), this article discusses - from the perspective of the social ecosystem of language - argumentative and interactional strategies used by law professionals to justify the use of forms of treatment in a judicial sentence available on websites and, in another case, during a session of the Supreme Federal Court. Based on the theory proposed by Couto et al. (2016), from a multi-methodological perspective, based on Critical Ecosystem Linguistics (LEC), in the perspectives of the theories of Interactional Sociolinguistics, with authors such as Kerbrat-Orecchioni (2006), Irvine (1978) Gracio (2010), Blommaert (2014), Ochs (1979), Levinson (1992), which involve concepts about argumentation and Conversation Analysis, the corpus was analyzed specifically in the cropped part exposed in some news sites - such as Exame, Terra and Epoca - and platforms for sharing digital information - like Instagram and Twitter. The methodological guidance is qualitative, documentary and bibliographic, with data collection in the virtual public domain. The analysis of the corpus includes results based on concepts in the area such as diversity, (dis)harmony, adaptation in language, communion and social suffering - the latter caused, mainly, by the repercussion of criticism in the virtual environment.


FIELD: medicine, pharmaceutics. SUBSTANCE: composition for treating oxidative stress comprises ball-shaped lipoic acid or one of salts thereof, and at least one lipophilic medium. The lipoic acid balls represent particles consisting of an inert core (a nucleus) coated with lipoic acid which is coated with a first layer of an isolating polymer, and with a second polymer layer resistant (stable) at gastric pH. What is also described is a preparation for treating oxidative stress with an unified dose containing the above composition. The preparation is presented in the form of a soft gelatin capsule. EFFECT: compositions according to the invention are stable in the lipophilic medium. 22 cl, 15 ex


This research proposes an approach towards an understanding of how Corporate Social Responsibility (csr) is dynamized in the hydrangea value chain in Antioquia´s east. An empirical study was carried out based on the Value Chain Analysis (vca), model that include csr variables, thereby the methodological design is based on a qualitative descriptive method, adopting a mixed non-probabilistic sampling approach. The data treatment and analysis was through ATLAS.ti software. The results proved that, since there are not certified csr practices, there are socially responsible attitudes and behaviors by traders and suppliers, each at different levels. In this way, it is concluded that the traders has a leading role in complying csr standards.


This study analyzes the relationship between long-term interest rates and a fiscal sentiment index originally developed by conducting textual analysis of newspaper articles from January 1, 1980, to March 24, 2017—a total of 134,742 articles. Daily frequency regression shows that the fiscal sentiment has significant effects on long-term interest rates as suggested by the conventional wisdom. Considering the literature which employs lower frequency data and concludes that fiscal conditions have statistically insignificant effects on interest rates or raises them by a statistically significant but economically modest amount, our method and results are quite novel. JEL Classification: E62, H62, H63


Objective
To explore the change regulation of periodical needs of main caregivers during transition period from being admitted to hospital to home among patients with initial stroke in 9 hospitals in Shanghai Pudong New Area and to analyze the reasons.

Methods
From May 2017 to January 2018, we selected 1 200 initial stroke patients and 1 200 main caregivers of them in 9 hospitals of Shanghai Pudong New Area as subjects by convenience sampling. The Family Needs Questionnaire (FNQ) was used to investigate the change of needs of them on admission, at discharge and two weeks after discharge. A total of 1 200 questionnaires were sent out and 1 089 valid questionnaires were collected.

Results
Among 1 089 main caregivers of initial stroke patients, the scores of importance of total demand on admission, at discharge and two weeks after discharge were (3.44±0.77) , (3.24±0.82) and (3.01±0.71) respectively with statistical differences (P<0.05) . At different stages, the need for health information and need for professional support were two dimensions with the high importance of care need of main caregivers among initial stroke patients; the stage with the highest satisfaction with the total demand was at discharge; the items with high rates of no satisfaction with needs included "to be shown that my opinions are used in planning the treatment" "to have enough resource for myself" and "to be shown what to do when the patient is upset" on admission, at discharge and two weeks after discharge.

Conclusions
The importance of total demand of main caregivers of initial stroke patients decreases with the increasing of disease course on admission, at discharge and two weeks after discharge. The need satisfaction is high at the stage of discharge and is low after discharge. Medical staff should strengthen the family follow-up.

Key words:
Stroke; Initial; Main caregiver; Periodical needs; Status analysis


In this paper,a Direct Transformation for F.Leberl Model (F.LDT) method for the solution to SAR directional parameters is introduced,which is derived from the F.Leberl equation on condition that the carrier's velocity being equal. In the experiments,we compared the results of the F.LDT method with that of the linear method. The results indicate that the F.LDT method is valid,which has the advantages of needing no initial value and no interation, What's more,it can avoid the case without convergence. Finally,we analysed the factors that affect the precision.


The football game is the most complicated sport about competitive strategy in all the sports events.The essence of football game is the team vitality confrontation.In order to form the competitive advantage,it is necessary to determine the thinking base point of the competitive strategy.By using the given method and logical analysis method,this paper will make deep research on strategy base point and method,and present that the basic points for football competitive advantage formation is the relative position of players,the ball and the goal,which should adopt space and time advantage to form dominant relative position,and form competition advantage finally.