This article outlines the trajectory of Dionysos' myth, the deity of intoxicating ecstasy and the sacred lyricism, and investigates what distinguish as sacred Dionysian that goes beyond the limits authoritative by moderate Apollo, as well as the rudiments of ritualistic dances and the beginning of the Greek theater . For this, retraces the path of Dionysus in ancient times, exploring the imagery of creation and its various expressions ground of the mythology, the symbolism, rituals and art as conditions for its survival in Classical Greece. The main objective is to demonstrate the syncretic plot of the symbology of these elements in different cultural expressions which are rooted and originate decisions and actions that shape the boundaries between objectivity and subjectivity in the conception of artistic materiality, placing this in the transcendent area that is transfigured in real. In this discussion, it addresses the aspect of Dithyramb and agrarian rituals that revive symbolism, imagery and resignify archaic myths that reactualized and vivify prehistoric rituals in contemporary times.


This study investigated a suitable filler metal, diffusion depth of the elements of this filler metal in the base metal, and its effect on the mechanical properties of brazing bonding of sheets with different thicknesses of 304L stainless steel. For this purpose, brazing was performed with thermal induction under a vacuum of 10−5 mbar and filler metal BNi-2 at the corner structures. First, the microstructure of different joint regions including base metals, Ni affected areas, and interfaces were examined by scanning electron microscopy and then the relationships between microstructure and microhardness were compared. In sheets with different thicknesses, the differences in diffusion depth were observed. Moreover, the microhardness of different areas of the braze was revealed to be completely affected by the diffusion of nickel. Finally, it was found that, for the bonding between 304L sheets with different thicknesses, BNi-2 filler metal had reasonable strength, diffusion, and filling for vacuum applications.


1. Introduction: Cyberbullying: Development, consequences, risk and protective factors Ersilia Menesini and Christiane Spiel 2. A longitudinal study of cyberbullying: Examining risk and protective factors Kostas A. Fanti, Andreas G. Demetriou and Veronica V. Hawa 3. Recalling unpresented hostile words: False memories predictors of traditional and cyberbullying Manila Vannucci, Annalaura Nocentini, Giuliana Mazzoni and Ersilia Menesini 4. Cyberbullying and traditional bullying in adolescence: Differential roles of moral disengagement, moral emotions, and moral values Sonja Perren and Eveline Gutzwiller-Helfenfinger 5. Cyberbullying in context: Direct and indirect effects by low self-control across 25 European countries Alexander T. Vazsonyi, Hana Machackova, Anna Sevcikova, David Smahel and Alena Cerna 6. Cyber-victimization and popularity in early adolescence: Stability and predictive associations Petra Gradinger, Dagmar Strohmeier, Eva Maria Schiller, Elisabeth Stefanek and Christiane Spiel 7. Processes of cyberbullying, and feelings of remorse by bullies: A pilot study Robert Slonje, Peter K. Smith and Ann Frisen 8. How stressful is online victimization? Effects of victim's personality and properties of the incident Frithjof Staude-Muller, Britta Hansen and Melanie Voss 9. The association between the mental health and behavioural problems of students and their reactions to cyber-victimization Julian J. Dooley, Therese Shaw and Donna Cross


OBJECTIVE
A site visit protocol was developed to assess recovery promotion in the organizational climate and culture of programs for veterans with serious mental illnesses.

METHOD
The protocol was pilot-tested in 4 programs: 2 that had scored high on the pilot version of a staff survey measure of program-level recovery promotion and 2 that had scored low. Two-person teams conducted onsite visits and assigned global and organizational domain ratings. Interrater agreement was assessed by examining adjacent agreement and computing weighted kappa.

RESULTS
The on-site protocol had good interrater agreement and discriminated between sites that scored high and low on the staff survey.

CONCLUSIONS AND IMPLICATIONS FOR PRACTICE
This site visit protocol and procedure shows promise for evaluating recovery promotion in milieu-based programs. After further refinement of this tool, adaptations could be developed for accreditation protocols or for program self-assessment and quality improvement efforts. (PsycINFO Database Record (c) 2019 APA, all rights reserved).


The current oversimplification of the amnesty issue has created a narrative that international law prohibits granting and admitting the effect of amnesties for core crimes. However, even if a domestic amnesty is found illegal under international law, it is still valid at the national level. The International Criminal Court (icc) cannot ignore the existence of and the legal consequences of such 'illegal' amnesties in assessing the admissibility of a case. This article categorises amnesties into three types and clarifies the legal and factual effects of internationally illegal domestic amnesties for the icc and the legal logic under which the icc treats such amnesties at the admissibility stage based on the developing applicable laws. This study provides clear guidelines on the conditions that would make a case inadmissible before the icc for both the chambers and the domestic policy makers and legislators who design amnesties.


Chiral acrylates 4a, 4b and 4c, derived from primary alcohols with a single stereogenic centre, were studied for possible diastereoface differentiation in their Lewis acid catalyzed Diels-Alder reaction with cyclopentadiene. No relevant diastereomeric excess was observed for the tert-butyl derived 4a. On the other hand, moderate but significant diastereomeric excesses (72-76 %) resulted when the trityl derived acrylates 4b and 4c were used. The ability of enforcing a 1,3-parallel orientation between the aryl shielding group and the acrylate moiety by incorporation of a tert-butyl or trityl anchoring substituent in the connecting chain is qualitatively assessed by 1H NMR.


Imitation learning allows learning complex behaviors given demonstrations. Early approaches belonging to either Behavior Cloning or Inverse Reinforcement Learning were however of limited scalability to complex environments. A more promising approach termed as Generative Adversarial Imitation Learning tackles the imitation learning problem by drawing a connection with Generative Adversarial Networks. In this work, we advocate the use of this class of methods and investigate possible extensions by endowing them with global temporal consistency, in particular through a contrastive learning based approach.


Based on AERONET measurements, aerosol absorption properties over 23 AERONET sites are analyzed. The properties include aerosol single scatter albedo (SSA), correlation characteristic of SSA with aerosol optical thickness (AOT), absorption optical thickness and absorption wavelength index. The index is introduced to indicate wavelength-dependence of absorption optical thickness. Among the 23 sites, 8 sites locate over Asia, 3 over Africa, and 12 in USA. Some results are summarized as follows: 1)Total mean absorption optical thickness for the 440nm-wavelength changes between 0.0061 (Howland, USA) and 0.0939 (Beijing, China), and it ranges from 0.0019 (Howland) to 0.0457 (Yulin, China) for the 1020nm wavelength. There are three peaks of absorption optical thicknesses, locating over China, India and north-Africa, respectively. 2)Over all sites except for two sites (Goa-india in India and Dahkla in Africa), correlative coefficients between SSA and AOT are positive, changing from 0.048 to 0.692. This characteristic implies that relative contribution of stronger-absorbing aerosol component to total AOT decreases when the AOT increases. In other hand, correlative coefficients between Angtr&diaero;m index and AOT are usually negative, showing trendily increasing contribution to total AOT from larger particles when the AOT increases. 3)Apart from two sites of Dahkla and Ilorin in Africa, absorption wavelength index is 0.09-1.29 less than Angtr&diaero;m index, the smallness being larger for some sites in USA. Usually, the larger Angtr&diaero;m index is, the stronger the smallness.


Objective Toinvestigatetheimmuneexemptionfor islet allografts induced by the Fas ligand expressed by cotransplanted testicular Sertoli cells in rats. Methods Allogeneic islets and testicular cells were cotransplanted in diabetic recipients. Allografts survival time, the cytotoxicity of Sertoli cells to activated lymphocytes in vitro, the apoptosis of infiltrative lymphocytes in allografts and the islets function were analyzed. Results All rats receiving islet allograft alone returned to a diabetic state by several days, and mean survival time of istel allograft was (6±1)days. When islets were cotransplanted with 5×10 6 testicular cells, the mean survival time of islet allografts was (10±1)days. When the quantity of testicular cells increased to 1×10 7, all of the animals remained normoglycemic throughout the follow up period (more than 50 days). The Fas ligand expression by cotransplanted Sertoli cells induced apoptosis of activated lymphocytes and delayed islets rejection. The islets cotransplanted with testicular cells had insulin secreting function. Conclusion Fas ligand expressing testicular Sertoli cells induce apoptosis of activated lymphocytes. Cotransplantation of allogeneic islets and testicular cells allows long term survival of allogeneic islets as a result of immune exemption.


From sustainable development viewpoint the situations of building energy consumption in our country are introduced. In view of energy-saving of wall, door and windows and roof as well as the utilization of solar energy and ventilation practical energy-saving measures are proposed in order to realize double-purpose of energy-saving and environmental protection.


ABSTRACT Narrative analysis is a methodological approach that has gained popularity in the social sciences in the last 30 years. Yet, this method of inquiry has been relatively neglected by tourism scholars. While some work in tourism employs narrative analysis, there are no studies that explore the specific types of narrative analysis privileged by tourism scholars. Also, little is known about the paradigmatic beliefs that inform narrative analysis in tourism. This paper presents a critical analysis of the studies employing narrative analysis in tourism. More specifically, this work examines all the articles published in tourism and hospitality journals to identify the types, paradigms, and methods privileged by tourism scholars using narrative analysis. Overall, the results reveal that while most of the studies privilege thematic analysis as approach to narrative analysis, a conspicuous number of articles do not refer to any specific methodological approach. Moreover, this work shows that tourism scholars tend to neglect important contextual aspects of narrative work, such as researcher's reflexivity, narrator's biographies, interactional terrain, and situational context. The findings of this study are important as they provide guidelines and recommendations that tourism scholars willing to employ narrative analysis in their future research endeavours could take into consideration.


The authors develop a parallel strategy to compute K-terminal reliability in 2-trees and partial 2-trees. They also solve the problem of finding the most vital edge with respect to K-terminal reliability in partial 2-trees. The algorithms take O(log n) time with C(m,n) processors on a CRCW PRAM, where C(m,n) is the number of processors required to find connected components of a graph with m edges and n vertices in logarithmic time.


The article is concerned with three trips, which the members of the
Habsburg family took to the westernmost regions of the Czech Lands, i.e. the
Cheb region in the course of 17th and 18th centuries. The importance of Cheb
in the early Modern Times was largely strategic, so the Habsburgs visited it
mostly for military reasons: in 1647, Ferdinand III appeared in the surroundings
of the town, heading the Imperial Army in order to liberate Cheb from the
Swedish grip. In 1673, Leopold I arrived there to stage a military parade of
the Imperial Army on its way to the Holy Roman Empire against France and
in 1702, the future Emperor Archduke Joseph I passed through the town on
his way to the Rhineland Landau fortress and stopped there also on his return
journey. All of the mentioned visits to Cheb and its region had other goals, too:
for example, a diplomatic meeting with the Elector of Saxony Johann Georg
II in 1673, while other visits included spa treatments or hunting in the town
surroundings.


The Covid‐19 pandemic, and the actions associated with attempting to arrest its spread, has greatly impacted sport. How did this affect the game results this season just passed?


How to delete courses in Alma using Alma API. Analysis of Alma API and workflow for creating Python script for deletion of courses that don't have reading lists.


The first kidney donor had suffered a head injury in a road traffic accident. After donor nephrectomy the kidney was immediately perfused with Perfudex for 10-20 minutes and placed with the perfusate in a sterile bag and stored in ice until transplantation six hours later. The blood group and tissue type of the patient was Al,;RhD-; HLA-Al, 2 B5, 8, and of the donor Al, RhD (Dr Barbara Dodd, department of forensic medicine, London Hospital Medical College); HLA-Al, 2 B5A, 8 (B5A is a local "split" of HLA-B5). Eighteen days after the transplant and one day before transplant nephrectomy no RhD antibodies were detected in the patient's serum. Two months later, before a successful second graft, RhD antibodies were first detected and have remained present to the same titre (1/4 by serum albumin and indirect antiglobulin technique) in all subsequent samples tested to date. No cytotoxic antibodies were detected after routine screening of the same samples against a reference panel representing all HLA-A, B, and C antigens. The first grafted kidney never functioned and two weeks after transplantation a biopsy showed total infarction and the kidney was removed shortly afterwards. Histology of the kidney was therefore non-informative.


On applying electrical pulses to sections of guinea-pig cerebral cortex in oxygenated glucosebicarbonate media their content of Na+ increased, and their content of K+ fell from 60±4 (8) to 49 ± 4 (8) pequiv./g. wet wt. in the course of 10 min. (Cunimins & McIlwain, 1960). Rapid re-entry of K+ ensued when pulses were stopped, the average rate during the first minute being 600 /equiv./g./ hr.; this re-entry did not occur if glucose was lacking, nor if 30 uM-2:4-dinitrophenol was present. Re-entry of K+ was inhibited by the relatively low concentrations of clupein sulphate (0-1 mg./ml.) which inhibited respiratory response to pulses (Mcllwain, 1959). These concentrations had little effect on tissue K+ in the absence of pulses, nor did they prevent the loss in K+ caused by pulses. They however preserved a large part of the phosphocreatine in the tissue from the diminution which usually accompanied the application of pulses. Protamine no longer inhibited re-entry of K+ when gangliosides were added [0-3 mg./ml. of preparations containing 26-29% of N-acetylneuraminic acid; for other interactions with cerebral tissues see Mcllwain (1960)]. This was not simply due to combination between protamine and gangliosides apart from the tissue, for protamine acted also when tissue was exposed to it for only 15 min.; tissue then rinsed free from protamine-containing medium and incubated in fresh media remained inhibited. If, however, this second medium contained gangliosides, normal movements of K+ were observed. It is proposed that the native gangliosides of normal tissue offer acidic sites which function in relation to the active cation transport which utilizes energy-rich phosphate. These sites are pictured to be occupied preferentially by the polybasic protamine.


The thesis begins with an analysis of the nutritional aspects of foods. In particular, the concept of balanced diet has been discussed, by referring to the principles of "mediterranean diet".
Just from this food model, the "optimation" draws inspiration, a technique developed and used to plan meals consistent with specific nutritional standards (15/30/55 between protein, fat and carbohydrate on the total energy intake, typically Mediterranean).
These food preparations have been tested through sensory analysis methods.
The next step is the extension of "nutritional optimization" concept to the "environmental optimization" one, owing to the presumed lower environmental impact of the Mediterranean diet.
LCA (Life Cycle Assessment) is the technique used to assess the environmental impact of various food products, such as frozen vegetables, cured meats, dairy products.
A further step is the creation of a communication tool, a new environmental label, designed to be used by companies to communicate their environmental performance and therefore their commitment to continuous improvement, and by consumers to obtain more information on the environmental impact of the foods daily consumed, in order to increase their critical sense and make purchases in a conscious way.


The varying real-world road conditions (eg. slopes, speed limits) have great effects on the vehicle dynamics and fuel characteristics. The lack of consideration for these effects may lead to deteriorative fuel economy and even collisions. This paper presents a hierarchical control framework for a connected and automated vehicular platoon subject to time-vary uncertain dynamics and uniform communication delays. This control method minimizes the fuel consumptions and ensures the tracking performance on the premise of collision-free property. Firstly, a centralized ecological speed planning (CESP) algorithm based on dynamic programing (DP) is designed as the upper layer. This layer produces the fuel-optimal and feasible speed profiles, which can be followed by all vehicles, for the entire platoon based on the preview information of road conditions (eg. slopes, speed limits). Secondly, the distributed collision-free speed tracking control (DCST) method is proposed in the lower real-time control layer. The collision-free property is guaranteed by the uniform boundedness performance of the well-designed potential function of the spacing error. The convergences of all speed tracking errors are proved through barbalat's lemma. By modifying the desired spacing model, the application range of DCST is extended to the conditions with large initial deviations. Finally, the main theoretical results are verified through numerical simulations.


Abstract
 The theory of measuring economic welfare across horizontal and vertical chains is provided in this chapter. As demonstrated, it underlies the spatial price equilibrium (SPE) trade models. The vertical and horizontal chains involved in a particular trade model, referred to as the REPA model, are described as an illustration.


Nano-inkjet printing using an Electrohydrodynamic's (EHD) pulsed cone-jet approach has the potential to bring affordable additive manufacturing to the micro and nanoscale. Ink technology is a major limitation of current EHD techniques. Specifically, most EHD printing processes print either nanoparticles or polymers. The materials are structurally weak and often have poor electrical or mechanical properties. For example, printing nanoparticles effectively creates a cluster of nanoparticles that must be sintered to create a continuous material. To address these issues, we have been adapting reactive inks to work with an EHD pulsed cone-jet. Specifically, we demonstrate that silver micron-scale structures can be printed using an EHD pulsed cone-jet regime. These inks produce solid structures without sintering steps and with good electrical properties.^1,2 This work shows that reactive ink chemistries can be combined with EHD printing to produce fine-resolution features consisting of solid metal without an annealing step.


The discovery of oil and gas in commercial quantities in Ghana has given the nation a hope that a great deal of the prevailing depressive economic hardships would be greatly mitigated. This can only materialise when the wealth from the natural resources such as oil and gas is well managed in promoting a well sustained economic development. Unfortunately, every natural resource discovery comes with its own challenges. This paper seeks to identify the major challenges of Ghana's oil and gas discovery and the structures to deal with these challenges. It is concluded that the country has most of the regulations and institutions already in place and that it should ensure their functionalities.


Human life, both directly and indirectly, has been influenced by developments in the field of information and communication technology, one of which is in the library field. The library is one place where information and knowledge are easily obtained. But now libraries are still more often found in physical form where access to locations is still an obstacle. There are still many libraries that only provide a collection of printed books, making it difficult in the search process, and need more space to accommodate the collection of books. The manual lending and repayment process causes services to be less effective and efficient. The author tries to create an android application-based library system with the name Dilib-Us where there are search, loan and return features that can improve the quality of library services. This system applies the data collection method and prototype method as a system development model. The purpose of this study is to facilitate service users in finding information on libraries through the Dilib-Us application. It is expected that this application can provide facilities for prospective borrowers in the process of borrowing and returning books and for librarians in processing data, such as: adding, changing and deleting data.


Nine years ago 1Vuttall* first described the bactericidal action of the Mood, suggesting at the same time that the other fluids of the body may possess a similar action. He found later that the aqueous humor, pericardial fluid, and a pleuritic fluid poor in cellular elements also possessed bactericidal power. Prudden t determined that ascitic fluid, fluid taken from a hydrocele, and the liquor amnii of the pig had the same properties. As far as we have been able to ascertain, no systematic examination of all the body fluids, in regard to this point, has ever been made. Flexner$ found that the blood serum of the human placenta was not distinctly germicidal for the Staphylococcus aureus, but was germicidal for the Bacillus typhosus. Caution in drawing conclusions as to the germicidal action of body fluids not hitherto examined is manifestly necessary. A controversy having lately arisen as to the channels of absorption of serous fluids, it seemed to us a matter of importance to determine whether lymph from the thoracic duct possesses bactericidal powers. The possibility was present that an exchange of the bactericidal factors between the blood and lymph-lymph f~-om the interstitial spaces-might occur only through the walls of the blood-vessels. Lymph from the thoracic duct might not therefore possess any action.


The evolution of hominid behavioral ontogeny can be reconstructed using two lines of evidence: first, comparative neontological data on the behavior and development of living hominoid species (humans and the great apes), and second, comparative paleontological and archaeological evidence associated with fossil hominids. (Although behavior rarely fossilizes, it can leave significant traces.)1 In this chapter I focus on paleontological and neontological evidence relevant to modeling the evolution of the following hominid adaptations: (1) bipedal locomotion and stance; (2) tool use and tool making; (3) subsistence patterns; (4) growth and development and other life history patterns; (5) childbirth; (6) childhood and child care; and (7) cognition and cognitive development. In each case I present a cladistic model for the origins of the characters in question.2 Specifically, I review pertinent data on the following widely recognized hominid genera and species: Australopithecus species (A. afarensis, A. africanus, and A. robustus [Paranthropus robustus]), early Homo species (Australopithecus gahri, Homo habilis, and Homo rudolfensis), and Middle Pleistocene Homo species (Homo erectus, Homo ergaster, and others), which I am calling erectines.


The distributions of discrete, continuous and conditional multiple window scan statistics are studied. The finite Markov chain imbedding technique has been applied to obtain the distributions of fixed window scan statistics defined from a sequence of Bernoulli trials. In this manuscript the technique is extended to compute the distributions of multiple window scan statistics and the exact powers for multiple pulse and Markov dependent alternatives. An application in blood component quality monitoring is provided. Numerical results are also given to illustrate our theoretical results.


There are no papers examining the labellar micromorphology in Malaxidinae in detail. The aim of this paper is to present the results of labellar micromorphology of our studies on Malaxidinae . The micromorphology of nine species was examined and described (calli, nectaries, OP structures, concavities). These species are divided into six groups of which the lip morphology probably represents different forms of attracting and rewarding pollinators. Group one consists of Disticholiparis gregaria and Platystyliparis aurita with characteristic globular nectary and pad-like callus. The second group with Liparis nervosa has two conelike convexities. The third one is represented by Liparis sutupensis with spread lip, the basal callus, and the epichile often eroding with age. The fourth group ( Stichorkis cespitosum ) has a massive hypochil with basal callus and delicate epichil. The fifth group ( Microstylis ophioglossoides , Dienia ophrydis ) is characterized by a lip with developed lateral lobes, three deep concavities in the middle part, an erect callus, and many raphide cells. Crepidium cf. rheedii and Crepidium dryadum from the sixth group have a three-lobed lip with entire or toothed mid-lobe, basal callus, cavity surrounded by a rim and OP structures with raphide cells. We also emphasized the different way and place of nectar secretion in the subtribe and gave some suggestions about pollination strategies.


Finding the mechanism that will make us live a long and healthy life is the goal of medical research. How appropriate that Klotho, the Greek goddess of life is involved in vascular disease. Klotho is one of the Greek Moirai, the goddesses of fate who controlled the ultimate destiny of man: death. Klotho spins the thread of life, Lakhesis measured the thread of life, and Atropos cut the thread of life. For this reason, the gene that seemed to control aging was named Klotho when first discovered by Kuro-o et al in 19971. This klotho knock out 'aging' mouse suffered from early demise, infertility, arteriosclerosis and arterial calcification, osteoporosis, hyperphosphatemia, emphysema and skin atrophy. This landmark discovery has not (yet) extended our life span, but has opened up an amazing understanding of the role of Klotho and mineral homeostasis in the pathogenesis of cardiovascular disease. (SELECT FULL TEXT TO CONTINUE)


The Deoban structural belt of the Tons Valley is lithostratigraphically divided into three Groups-the lower Dharagad Group, the middle Deoban Group and the upper Jaunsar and Simla Groups. The contact between the Dharagad and Deoban Groups is an angular unconformity, while the one between Deoban and Sirnlajfaunsar Groups varies from disconformity to paraconformity. The rocks of the Jaunsar Group are thrust over Deoban and Simla Groups along the south hading Tons thrust. The Sherar syncline, a prominent, NE-SW trending doubly plunging syncline, affecting the Deoban and Simla Groups and truncated by the northwest trending main Himalayan folds is considered a remnant fold of an earlier orogeny.


This paper deals with sliding cause,deformed characteristics and stability of the Miaodixia landslide based on field survey and laboratory test.Control of the landslide is discussed.


Economic benefits which stem from the highway construction program and Lhe purchasing of land to be used as right of ~ay for these highways are substantial and far-reaching. There are also certain minor isolated economic detriments because of anticipated highway construction and because of the relocation of existing highways. Some of the economic benefits are clearly visible and others-even though equally as great-are not as readily discernable. At the present time, there is a great deal of talk and interest about the wonderful job that is being done to attract new industry and to otherwise stimulate the economy of the State of Kentucky. I assume that practically all far-sighted Kentuckians agree with the general philosophy involved here and are proud of the excellent progress that is increasingly evident. From time to time, we read in the newspapers thumbnail sketches of the total payroll volume, the total tax benefits, the total buying power, and the numerous other indices of benefits which stem from tMs program of growth and expansion. We also read periodically about the total dollar volume of highway construction contracts in the State of Kentucky. There are direct and rather striking economic benefits to the state stemmjng from this construction activity. A recent issue of "The Resi.clential Avvraiser" gave the following estimate :


Preface Part 1: Raising Money for your Technology Dream: Importance of Getting the First Partner Right Overview 1. Star+Globe Technologies and Virginia Cha 2. Pixelmetrix and Danny Wilson 3. Sinetics Associates and Danny Chng Part 2: Plunging into the Market: Managing Dilemmas and Keeping Afloat 4. Finesse Alliance and Chak Kong Soon 5. PlaNET Technology Solutions and Ronnie Wee 6. System Access and Leslie Loh 7. Systems@Work and Ng Fook Sun Part 3: Coaches: Modern Singapore's New Crop of Funding Schemes and Incubation Programs Conclusion Part 4: Teaching Cases


Abstract 4,4′-Dinitrodiphenyl disulfide (1) reacted with liquid ammonia to give 4-nitrobenzenesulfenamide (2) and 4-nitrobenzenethiol (3). The 4-nitrobenzenesulfenamide (2) thus formed reacted further with liquid ammonia to afford 4-nitroaniline (4) unexpectedly at relatively low temperatures. The unexpected reaction is presumed to proceed via the formation of a sulfonium intermediate (7).


Community and police are supposed to live side by side in order to maintain public order. But all of that were undeniable with the problems faced by the police. As the number of news in the media about the police who commit crimes. Because society is more critical now with the problems that occur, especially in the presence of criminal acts by police, so does society tend to view police cynical figure. Police image in the eyes of society is becoming worse.
The purpose of this study is to describe the formation of public opinion about the image of police as the impact of crime news by the police and raised in the media. The theory used is the spiral of silence theory by Elizabeth Noelle-Neumann. This study used qualitative methodology with a case study approach. This approach tries to describe in detail the topic under study.
The results showed that the process of forming opinions about the image of police as the impact of crime news by the police a little experience the difference with the process of forming opinions expressed W. P. Davidson (Kasali, 2003:25). Initial assumption that the formation process begins with the formation of perception by four factors: experience, cultural background, shared values, and the news that develop to form opinions, and opinions will be formed after the formation of consensus. In contrast to the results of research showing that perceptions are formed only from the experience and exposure to mass media so as to form an opinion. Disclosure of his opinions were not necessarily public opinion, but opinion was divided first into minority and majority opinions. Only the majority opinion was forming a consensus and public opinion.

Keywords: Image, Opinion, Spiral of Silence, Case Study, Perception


: The Ecuadorian government has carried out massive programs aimed at labor insertion for the disabled. The environment and the factors that affect the labor insertion of people with disabilities in Ecuador were analyzed. Within the results, it was found that there is a legal framework and tax incentives that promote the labor inclusion of this priority attention group, but there are no complete statistical data to confirm the results of these measures.


InAs/GaSb T2SL photodetectors offer similar performance to HgCdTe at an equivalent cutoff wavelength, but with a sizeable penalty in operating temperature, due to the inherent difference in Shockley-Read lifetimes. It is predicted that since the future IR systems will be based on the room temperature operation of depletion-current limited arrays with pixel densities that are fully consistent with background- and diffraction-limited performance due to the system optics, the material system with long Shockley-Read lifetime will be required. Since T2SLs are much resisted in attempts to improve its SR lifetime, currently the only material that meets this requirement is HgCdTe. Due to less ionic chemical bonding, III-V semiconductors are more robust than their II-VI counterparts. As a result, III-V-based FPAs excel in operability, spatial uniformity, temporal stability, scalability, producibility, and affordability – the so-called "ibility" advantages.


The formation of platelet-leukocyte aggregate (PLA) was mediated by adhesion molecules. PLA formation plays an important role in both the development and progression of atherothrombotic diseases. Clinical studies have found that PLA formation was increased significantly in patients with such diseases. The PLA formation is affected variously by various antiplatelet agents. Monitoring of PLA formation is helpful in guiding the clinical use and selection of antiplatelet agents.

Key words:
platelet-leukocyte aggregate; atherothrombotic disease; antiplatelet agent


In this study, we explain to the pricing hedging of derivatives infinite markets models. In this setting we work out of the key financial and mathematical ideas underlying modern derivatives. Asset analysis without having to deal with the technicalities stochastic calculus. We explain the notation of dynamic edging and introduce the concept of an equivalent martingale - measure. We discuss the fundamental theorem of asset pricing and derive the Risk- Neutral pricing principle. To illustrate these concepts we briefly discuss the Binomial model of Cox, Ross and Rubinstein (1979).


Objective: To evaluate the application value of SHEL model to prevent the nursing adverse events in operation room.Methods: The SHEL model system analysis of our hospital from 2011 in operation room nursing adverse events in 41 patients reported defects causes and monitoring management system,took corrective measures and track verification,carried on the comparative analysis of adverse events and take measures for rectification.Results: The improvement measures after the 2012 report,the operation room nursing adverse events in 17 patients and compared with that in 2011,reported incidence of adverse events was lower,the difference was statistically significant(P 0.05).Conclusion: The application of SHEL model to analyze the causes of adverse events,formulate effective measures according to the related factors,can reduce the adverse events.


Abstract Objective: We aimed to underline the surgical importance of the distances between the landmarks of the temporal bone, important for quantifying the benefits and disadvantages of two different cochlear implant techniques. Methods: We have gathered all data from the Radiology Department in Emergency County Hospital in Tîrgu Mureș, namely computed tomography imagistic studies in order to perform the required measurements, according to pre-defined inclusion/exclusion criteria. The time interval was 5 months. Results: The comparison between the sets of data shows a good match for the risk/benefit ratio for the two types of technique for cochlear implantation. Conclusions: The middle cerebral fossa approach for the electrode insertion into the cochlea is a viable and needed surgical technique as the classic approach has reached its boundaries and new challenges appear. As surgical decisions are largely based on radiology data, our work underlines the importance of solving the borderline pathology, the extreme cases and the role of surgery in improving the quality of life for every patient with cochlear implant indication.


From a narrative perspective, organizations' identities are discursive (linguistic) constructs constituted by the multiple identity-relevant narratives that their participants author about them, and which feature, for example, in documents, conversations and electronic media. By defining collective identities as the totality of such narratives I draw attention to their complex, and often fragmented and heterogeneous nature. My approach contrasts with much of the theorizing in this field which has tended to homogenize collective identities by emphasizing what is common or shared, failed to capture the interplay between different communities within organizations, and produced bland, undifferentiated empirical research. In particular, the theoretical framework that I outline focuses attention on the importance of reflexivity, voice, plurivocity, temporality, and fictionality to an understanding of collective identities as locales for competing hegemonic claims. In combination, these notions form a unique conceptual model for theorizing and researching collective identities. This said, a narrative approach also has its limitations, and is proposed as an additional, not exclusive, interpretive lens.


Atomistic simulation methods are used in order to investigate the surface structure of the zeoliteclinoptilolite. Clinoptilolite has been represented by mean...


8 Chapter (1) Introduction 9 1:1) Research Aim, Objectives and Research Question 13. Chapter (2) Literature Review: Includes Themes and Background Theory 17 2.1) Evolving Social Expectation from Liners to Cruise Ships 20 2.2) Marketing and Cruise Consumers 28 2.3) Marketing Nostalgia 35 2.4) Social interaction 40 2.5) Research Concept 49 Chapter (3) Methodology: Description of methodology including Data Theory & Ethics 53 3.1) Posivitism and Interpretivism 54 3.2) Ethics and Values in Research 57 3.3) Research Approach 60


This study aimed to investigate the application of a bioimpedance spectroscopy technique, based on the current response to a voltage step excitation, as a diagnosis tool to the knee osteoarthritis problem. Up to now, 14 individuals (4 men and 10 women) have participated of the study, being grouped as health subjects (NG) and subjects with knee osteoarthritis diagnosis (OG). A total of 28 bioelectrical impedance measurements in the knee joint have been made. The average value of the knee intracellular resistance was of 281 82.6 Q in the NG and 143/spl plusmn/33.9 Q in the OG. Besides this difference is statistically significant (p<0.01) between the groups, ratio between the intracellular and extracellular resistances, that was of the 1.6/spl plusmn/0.5 in the NG and 0.8/spl plusmn/0.2 in the OG, seems to be a better index to be used in the diagnosis. The results of this study suggest that the proposed method of bioelectrical impedance evaluation, when applied the diagnosis of the knee, is a valid method to determine the inflammatory pathological conditions of this joint.


There is an evident need for monitoring pollutants and/or other conditions in river flows via wireless sensor networks. In a typical wireless sensor network topography, a series of sensor nodes is to be deployed in the environment, all wirelessly connected to each other and/or their gateways. Each sensor node is composed of active electronic devices that have to be constantly powered. In general, batteries can be used for this purpose, but problems may occur when they have to be replaced. In the case of large networks, when sensor nodes can be placed in hardly accessible locations, energy harvesting can thus be a viable powering solution. The possibility to use three different small-scale river flow energy harvesting principles is hence thoroughly studied in this work: a miniaturized underwater turbine, a so-called 'piezoelectric eel' and a hybrid turbine solution coupled with a rigid piezoelectric beam. The first two concepts are then validated experimentally in laboratory as well as in real river conditions. The concept of the miniaturised hydro-generator is finally embedded into the actual wireless sensor node system and its functionality is confirmed.


Lymph node (LN) stromal cell-derived laminins α4 and α5 are differentially regulated in tolerance (α4>α5) and immunity (α4<α5). We previously showed that depleting fibroblastic reticular cell (FRC)-derived laminin α4 reduced Foxp3+ regulatory T cells (Tregs) while depleting FRC-laminin α5 increased Tregs. We hypothesized that clinically available immunosuppressants regulate immunity by altering LN structure.
 B6 mice received tacrolimus, rapamycin, prednisolone, mycophenolate mofetil (MMF), or FTY720 for 3, 7, and 30 days. Peripheral LNs (pLN) and mesenteric LNs (mLN) were analyzed by immunohistochemistry. Intestinal permeability (IP) was analyzed by FITC-dextran gavage.
 Both tacrolimus and rapamycin resulted in early, transient, mixed pro and anti-inflammatory effects on LN laminin α4:α5 ratios, but resulted in pro-tolerant LN Treg increases. Prednisolone had a pro-tolerant effect by increasing LN Tregs. MMF showed early, transient, pro-tolerant effects by increasing LN Tregs and laminin ratios. FTY720 resulted in early, transient, pro-inflammatory changes and increased IP after 7 days, but resulted in a pro-tolerant increase in LN Tregs after 30 days.
 Tacrolimus and rapamycin induced early, pro-inflammatory changes, yet both exerted later, pro-tolerant effects. Prednisolone displayed consistent pro-tolerant effects across all time points. MMF showed transient, pro-tolerant effects after 3 days, which disappeared by day 7. FTY720 resulted in early, transient, pro-inflammatory changes, later becoming pro-tolerant. Overall, immunosuppressants affect LN stromal laminin remodeling and Treg distribution. These results suggest a novel approach for evaluating the global effects of immunosuppressants in vivo.
 This study was supported by grants from the NIH (R01AI114496 and T32AI95190-10).


A review of the professional literature Widerman, 1995). I believe it is seldom suggests that many school counselors are that a school counselor can successfully receiving family counseling training and intervene in the life of a student with practicing this form of intervention with out considering the continuous influence various school problems (Ama tea & of the family as the primary social sys Fabrick, 1981; DiCocco, 1986; Hinkle, tern for the student. Failure to intervene 1993; Peeks, 1993). This development is at the level of the family system will often not surprising in view of the limited time result in limited, if any, resolution of the most school counselors have for interproblem presented by the student vention, their history of interacting with (Edwards & Foster, 1995; Walsh & Giblin, all components of the school context or 1988). system, and the unique potential that This article proposes that family coun school counselors have for the early idenseling models be developed that use the tification and resolution of emotional, school counselor's unique position as an behavioral, and social problems. The insider within the system of the school addition of a systemic lens and family (Foster, 1984). Furthermore, these fam counseling skills to a school counselor's ily counseling models should provide a repertoire seems to offer very promising framework for assessing the larger sys possibilities and outcomes (Amatea, tern within which the problem is embed 1991; Carlson, 1987; Carroll, 1993; Fine ded, for determining where the interven & Carlson, 1992; Fine & Holt, 1983; tion strategies should be directed, and Molnar & Lindquist, 1989). Although not for deciding how to assemble the neces disparaging other tasks performed by sary cast of characters. The following school counselors, the family counselfamily counseling model is an attempt ing proposed here concurs with previto offer practical guidance in making ous authors that families should become these important precounseling decisions, the primary focus of interventions per formed by school counselors (Goldenberg CUSTOME RSHIP & Goldenberg, 1981; Widerman &


This paper presents the final results of the ICDAR 2015 Competition on Video Script Identification. A description and performance of the participating systems in the competition are reported. The general objective of the competition is to evaluate and benchmark the available methods on word-wise video script identification. It also provides a platform for researchers around the globe to particularly address the video script identification problem and video text recognition in general. The competition was organised around four different tasks involving various combinations of scripts comprising tri-script and multi-script scenarios. The dataset used in the competition comprised ten different scripts. In total, six systems were received from five participants over the tasks offered. This report details the competition dataset specifications, evaluation criteria, summary of the participating systems and their performance across different tasks. The systems submitted by Google Inc. were the winner of the competition for all the tasks, whereas the systems received from Huazhong University of Science and Technology (HUST) and Computer Vision Center (CVC) were very close competitors.


In this chapter I provide a moral appraisal of the South Africa's Truth and Reconciliation Commission (trc) in the light of the indigenous1 sub-Saharan values from which it largely sprang,2 namely, those associated with talk of "ubuntu" in the Nguni languages of Zulu, Xhosa, and Ndebele as well as cognate terms such as "botho" in Sotho-Tswana. These terms literally mean humanness or human excellence, and serve as catchwords for complex African ideals that prize relationships such as communion, harmony, and cohesion. Which conception of national reconciliation follows from these relational values, and to what extent did the trc further it? Could the trc have done so more than it did, had it been configured somewhat differently? Given how discordant and fragmented South African currently is with respect to race, would a new trc be useful? I answer all these questions here, and do so by appealing to a philosophical interpretation of ubuntu. Instead of taking a given African people's understanding of ubuntu for granted, I draw on values and norms associated with it by an array of traditional southern African peoples in order to articulate a basic and comprehensive moral principle, one that even many outside the indigenous sub-Saharan tradition could find attractive. That is, I advance an interpretation of ubuntu that promises to serve as a public morality for a postindependence, multicultural South Africa (though not only it). After spelling out ubuntu as a contemporary social ethic, I indicate how it grounds a novel, communal conception of national reconciliation that is distinct from accounts that South Africa's Constitutional Court and other thinkers


High quality single lithium niobate (LiNbO3, LN) microwires and nanowires (MNWs) are synthesized by using the hydrothermal method. A propagation-distance-dependent output measurement is introduced to characterize the propagation loss in LN MNWs, and a typical loss of 0.15 dB/μm at a wavelength of 722 nm in an 830-nm-diameter LN MNW is obtained. Moreover, the advantages of wide-angle coupling and easy interconnecting are demonstrated through light transmission in a broken LN MNW optical waveguide.


A 3-layer graded-bandgap solar cell with glass/FTO/ZnS/CdS/CdTe/Au structure has been fabricated using all-electrodeposited ZnS, CdS and CdTe thin layers. The three semiconductor layers were electrodeposited using a two-electrode system for process simplification. The incorporation of a wide bandgap amorphous ZnS as a buffer/window layer to form glass/FTO/ZnS/CdS/CdTe/Au solar cell resulted in the formation of this 3-layer graded-bandgap device structure. This has yielded corresponding improvement in all the solar cell parameters resulting in a conversion efficiency >10% under AM1.5 illumination conditions at room temperature, compared to the 8.0% efficiency of a 2-layer glass/FTO/CdS/CdTe/Au reference solar cell structure. These results demonstrate the advantages of the multi-layer graded-bandgap device architecture over the conventional 2-layer structure. In addition, they demonstrate the effective application of the two-electrode system as a simplification to the conventional three-electrode system in the electrodeposition of semiconductors with the elimination of the reference electrode as a possible impurity source.


In some environments the components may not fail fully but can degrade, and there may be multiple stages of degradation. In such cases, the efficiency of the system may decrease. In this study we present a model for predicting the reliability of k-out-of-n: G systems assuming that components are subjected to several stages of degradation as well as catastrophic failures. In the analysis we consider the state-dependent transition rates for the catastrophic failures and degradation processes. We also present the expressions to determine the reliability and mean time to failure (MTTF) of the k-out-of-n systems. Reliability and M TTF expressions for a special case of the model without catastrophic failures are also presented. Several numerical examples are given to illustrate the results.


A breakdown of a benchmark score is how much each aspect of the system performance affects the score. Existing methods require internal analysis on the benchmarking program and then involve the following problems: (1) require a certain amount of labor for code analysis, profiling, simulation, and so on and (2) require the benchmarking program itself. In this paper, we present a method for breaking down a benchmark score without internal analysis of the benchmarking program. The method utilizes regression analysis of benchmark scores on a number of systems. Experimental results with 3 benchmarks on 15 Android smartphones showed that our method could break down those benchmark scores even though there is room for improvement in accuracy.


This paper aims to present the methodology for measuring an ECG signal of a patient using GSM network and very large scale integration technique. ECG signals are generated artificially using a MATLAB code and the Additive White Gaussian Noise is added to an original ECG signal. The original signal and the signal with noise are compared and the noise from the signal are eliminated using the MATLAB. Then the signal will be converted into a digital form using VERILOG and then downloaded into a FPGA kit. The ECG monitoring system is then interfaced with GSM network.


It is an effective and reasonable method to install catalytic converter to reduce the emission of motorcycle. The place where the catalytic converter is installed will affect the result directly. This article used the software gambit to modeling the pipe, then it used the software fluent to analyze the inner flowing instance. According to the distributing of the velocity and pressure, the reasonable installed place was confirmed, and the emission was better purified.


Accurate, detailed maps of total ozone were not available until the launch of the Total Ozone Mapping Spectrometer (TOMS) in late 1978. However, the Scanning Radiometer (SR) on NOAA satellites during the 1970s included a visible channel that overlapped closely with the Chappuis absorption band of ozone around 600 nm. We use a simple calculation of two-way transmittance to obtain total ozone from data taken by the Advanced Very High Resolution Radiometer (AVHRR). THe AVHRR was the successor to the SR on NOAA satellites, and because it flew during the 1980s, we are able to compare our derived ozone amounts with those derived from TOMS. Our method works only over scenes whose albedos are large and unvarying.


Steve Mister, president and CEO of dietary supplements association the Council for Responsible Nutrition, told Nutritional Outlook that his organization is "optimistic" that Gottlieb will walk a "middle ground" on regulating the supplements industry.


In this paper it is shown that for corundum boules grown in a Verneuilapparatus the experimental distribution function of the angle of inclination for the trigonal axis measured against the direction of linear growth can be explained by a purely statistical concept. The analysis is based on a model of the processes dui ing crystal nucleation. Further applications, especially on cubic crystals, are also discussed.


In the gasoline engine of fuel injection type, atomization of fuel droplet and its distribution has directly influenced the performance of engine and harmful emission. To investigate atomization characteristics of fuel spray, in this paper fuel spray of air-assisted injector is observed at the various initial conditions of ambient air temperature and air assisted pressure. Behavior of fuel spray is photographed with microscopic visualization system. The SMD of fuel droplet is measured with PMAS (Particle Motion Analysis System). The effect of air-assisted pressure and temperature of ambient air resulted in the decrement of SMD and its variation. Finally, It was found that It was found that from spray angle at the two-hole injector had measured degree the result of photographs by shadow graphy. The mean diameter of suns decreased and the of droplets increased with increasing the temperature in the spray fields by the results of PMAS measurement. It was found that the characteristics of sprays became finer by increasing the temperature of spray fields about 373K without the delivery of air-assistance.


Fatty acyl reductases (FARs) catalyze the reduction of fatty acyl-coenzyme A (CoA) or -acyl carrier protein (ACP) substrates to primary fatty alcohols, which play essential roles in lipid metabolism in plants. However, the mechanism of FARs involved in male reproduction is poorly defined. Here, we found that two maize allelic mutants, ms25-6065 and ms25-6057, displayed defective anther cuticle, abnormal Ubisch body formation, impaired pollen exine formation and complete male sterility. Based on map-based cloning and CRISPR/Cas9 mutagenesis, Zm00001d048337 was identified as ZmMs25 gene, encoding a plastid-localized FAR with catalytic activities to multiple acyl-CoA substrates in vitro, and four conserved residues (G101, G104, Y327 and K331) of ZmMs25 were critical for its activity. ZmMs25 was predominantly expressed in anther at stage 9, and was directly regulated by transcriptional factor ZmMYB84. Lipidomics analysis revealed that ms25 mutation had significant effects on reducing most of cutin monomers and internal lipids, and altering composition of cuticular wax in anthers. Moreover, loss of ZmMs25 function significantly affected the expression of its four paralogous genes and five cloned lipid metabolic male-sterility genes in maize. These data suggest that ZmMs25 is required for anther development and male fertility, implying its application potential in maize and other crops.


The face is a small part of a human, but it plays an essential role in cemmunication. An open hybrid system for facial animation is presented. It encapsulates a considerable amount of information regarding facial models, movements, expressions, emotions, and speech. The complex description of facial animation can be handled better by assigning multiple input accessories. These input accessories may be a simple script, a multi-input musical keyboard, a gesture dialogue from the DataGlove, or some other type of interactive physical or virtual device. Integration of all means of control offers flexibility and freedom to the animator. The scope of such an open system is tremendous. The system described is written in C with the interface built on top of the Fifth Dimension Toolkit. The various input components are independent processes running on UNIX workstations. Communication between the processes is done through sockets in stream mode using Internet protocol. A figure illustrates the system processes. (Contains 17 references.) (MAS) * Reproductions supplied by EDRS are the best that can be made * from the original document. *********************************************************************** Communicating with Virtual Humans NADIA MAGNENAT THALMANN MIRALab, University of Geneva 24, rue du General-Dufour, CH 1204 Geneva, Switzerland E-Mail: firstname.lastname@example.com Abstract: In this paper, we present an open hybrid system for facial animation. It encapsulates a considerable amount of information regarding facial models, movements, expressions, emotions and speech. The complex description of facial animation can be handled better by assigning multiple input accessories. These input accessories may be a simple script or a multi-input musical keyboard or a gesture dialogue from the DataGlove or some other type of interactive physical or virtual device. Integration of all means of control offers flexibility and freedom to the animator. The scope of such an open system is tremendous. Virtual worlds would be desolate indeed without things like synthetic faces that we can relate to and understand. In this paper, we present an open hybrid system for facial animation. It encapsulates a considerable amount of information regarding facial models, movements, expressions, emotions and speech. The complex description of facial animation can be handled better by assigning multiple input accessories. These input accessories may be a simple script or a multi-input musical keyboard or a gesture dialogue from the DataGlove or some other type of interactive physical or virtual device. Integration of all means of control offers flexibility and freedom to the animator. The scope of such an open system is tremendous. Virtual worlds would be desolate indeed without things like synthetic faces that we can relate to and understand.


Several measures of average farm size are developed, using resource endowment, degree of industrialization, factor proportions as the explanatory variables for 53 countries. The three determinants explain much of the variation in average farm size, using cross-sectional regression techniques.


The optical properties and sensing performances of the molecular sensors based on plasmonic Fano‐resonance (PFR) nanostructures have been numerically investigated in detail. The on‐resonance sensor, in which the Fano‐resonance position is overlapping with the absorption‐band of the detected molecules perfectly, reveals a powerful ability to detect the molecules with a low concentration or thin thickness. By the bias‐modulation of a single‐layer graphene, the Fano‐resonance position of the nanostructures can be tuned effectively. On being modulated properly, the PFR sensor shows an ultrahigh performance because of the unprecedentedly high overlap of the Fano‐resonance position with the absorption‐band of molecules, which is enabling superior signal strength in the molecular detections based on their vibrational fingerprints. Our proposed strategy may enable the development of dynamic sensors and open exciting prospects for bio‐sensing.


Income system covers the national finance income and national property income,the two of witch reinforce each other,and including the internal contradiction and unity. Taxation is the connecting point of the two. Through the tax system,the part of national property income changes into national fiscal revenue; through fiscal expenditure system,national finance income for the people,promoting the national property income growth. The legal relation of the tax revenue is the legal relationship between the taxpayer and taxpayer 's rights,definiting from the attributes,witch is the relation between thenational taxation rights and national taxation power. Tax law reform should take the humanities concern and the ultimate value of human pursuit for the route,establish the conception of the people-oriented tax rights balance,which is the national tax rights and national tax power balance theory. Based on this, taking the research of national tax power and tax right balance interaction as a logical starting point to promote the reform of the fiscal and taxation system of China,discussion on establishment of tax rights into the constitution,statutory taxation,tax fairness,budget supervision mechanism,to explore a new path of Chinese tax law reform.


Abstract Suppose LC 1 and LC 2 are two machine learning classes each based on a criterion of success. Suppose, for every machine which learns a class of functions according to the LC 2 criterion of success, there is a machine which learns this class according to the LC 2 criterion. In the case where the converse does not hold LC, is said to be separated from LC 2. It is shown that for many such separated learning classes from the literature a much stronger separation holds: (∀𝒞∈LC 1) (∃𝒞' ∈LC 2 - LC 1(( [' ⊃𝒞] It is also shown that there is a pair of separated learning classes from the literature for which the stronger separation above does not hold. A philosophical heuristic toward the design of artificially intelligent learning programs is presented with each strong separation result.


We describe an algorithm that determines the z position of primary interactions in ATLAS using only space points from the precision silicon detectors (Pixel and SCT). No prior track reconstruction is required. The algorithm can be applied to either full events or regions of interest and is suitable for use at the second level ATLAS trigger. We present results and give examples demonstrating its performance at both high and low LHC luminosity. A T L -D A Q -2 00 201 4


A simple and efficient micropropagation method is developed for Commiphora wightii from the cotyledonary nodal segments of twenty one-day-old in vitro grown seedlings. Multiple shoots were initiated on MS medium containing IAA 0.1 mgl−1, BA 1.5 mgl−1 and additives consisting of 50 mgl−1 ascorbic acid, 25 mgl−1 each of citric acid, arginine and adenine sulfhate. The isolated shoots were multiplied on MS medium containing IAA 0.1 mgl−1, BA 1.0 mgl−1 and additives as in the initiation medium. Shoots were rooted on 1/2 strength MS medium containing 0.25 mgl−1 IBA. The rooted plantlets were hardened and transferred to soil.


Within psychoanalysis, BDSM (bondage, dominance, submission, sadism and masochism) has typically been interpreted as pathological, resulting from the (gendered) tension between assertion and recognition developed in the oedipal phases and enforced in dominant ideology. To practitioners, however, BDSM recognises the physical and psychological dependence of people on each other. The tasks inherent to successful BDSM redefine traditional masculine and feminine identity; dominants recognise their own dependence and submissives are independently powerful. Expanding on feminist psychoanalytic theory, this paper argues that BDSM relations may embody the psychologically ideal state of 'mutual recognition.' Practitioners take pleasure in connection without the threat of engulfment. Significantly, the skills developed in BDSM may help mediate a variety of interpersonal and institutional power relations.


A history of the Organization of Teratology Information Services (OTIS) is presented in context of the history of teratology information services. During the late 1970s, teratology information services grew out of the need for current and accurate information about fetal effects of environmental exposures in pregnancy. Over the next decade, teratology information services networked and collaborated, developing their own professional organization. A description of the activities of OTIS is described.


AIMS
Recently, strain and strain rate have been introduced as novel parameters reflecting left ventricular (LV) function. The purpose of the current study was to assess the prognostic importance of strain and strain rate after acute myocardial infarction (AMI).

METHODS AND RESULTS
A total of 659 patients after AMI were evaluated. Baseline echocardiography was performed to assess LV function with traditional parameters and strain and strain rate. During follow-up, 51 patients (8%) reached the primary endpoint (all-cause mortality) and 142 patients (22%) the secondary endpoint (a composite of revascularization, re-infarction, and hospitalization for heart failure). Strain and strain rate were both significantly related with all endpoints. After adjusting for clinical and echocardiographic parameters, strain was independent related to all endpoints and was found to be superior to LV ejection fraction (LVEF) and wall motion score index (WMSI). Patients with global strain and strain rate higher than -15.1% and -1.06 s(-1) demonstrated HRs of 4.5 (95% CI 2.1-9.7) and 4.4 (95% CI 2.0-9.5) for all-cause mortality, respectively.

CONCLUSION
Strain and strain rate provide strong prognostic information in patients after AMI. These novel parameters were superior to LVEF and WMSI in the risk stratification for long-term outcome.


Engineering properties of bedrock materials at Badlands National Park were used to develop models for Park managers to assess slope erosion and stability for fossil resource protection. Six fully instrumented sites were used to document slope conditions. Bedrock consisted of Oligocene White River Group rocks. Bulk erosion rates correlated to grain size with silty-sandy materials producing higher mass erosion rates as a function of the silt-to-clay ratio and plastic index. Data indicated that as grain size decreased, plastic index increased leading to a decrease in erodibility. These parameters were used to construct a grain-size proxy, ψ, that was substituted for grain size, D, in Bagnold's entrainment equation and provided significant improvement in calculation of critical entrainment velocities for fine-grained materials. Hydraulic analyses of slope and pediment surface processes indicated surface roughness was a controlling factor and materials washed from rough steep slopes were effectively transported across smooth low-angle pediments with slope-to-pediment angle ratios of nearly 6:1. Slope stability modeling of ten slopes produced high factors of safety for all slopes, even under saturated conditions and was attributable to clay cohesion. All results were used to construct models that predicted years until net slope erosion equaled 2.5 cm (1 inch). Using these results, Park managers were advised to visit erosion-prone sites on a 1- to 6-year schedule, based on site geology and slope aspect, to adequately protect critical fossil resources from destruction.


The objectives of this scoping review were as follows: (1) to describe what exercises and intervention variables are used in resistance training interventions for lower limb tendinopathy,  (2) to assess the completeness of reporting as assessed by the Consensus on Exercise Reporting Template (CERT) and the Toigo and Boutellier framework, and (3) to assess the implementation of scientific resistance training principles. We searched MEDLINE, CINAHL, AMED, Embase, SPORTDiscus, and Cochrane Library databases. Randomized controlled trials, cohort studies, case series, case reports, and observational studies that reported using resistance exercises for lower limb tendinopathies were considered for inclusion, with 194 studies meeting the inclusion criteria. Completeness of the reporting of exercise descriptors and programme variables was assessed by the CERT and the Toigo and Boutellier framework. Reporting of exercise descriptor items from the Toigo and Boutellier framework ranged from 0 to 13, with an average score of 9/13, with only 9 studies achieving a full 13/13. Reporting of items from the CERT ranged from 0 to 18, with an average score of 13/19. No study achieved a full 19/19; however, 8 achieved 18/19. Scoring for resistance training principles ranged from 1 to 10, with only 14 studies achieving 10/10. Eccentric heel-drops were the most common exercise (75 studies), followed by isotonic heel raises (38), and single-leg eccentric decline squats (27). The reporting of exercise descriptors and intervention content was high across studies, with most allowing exercise replication, particularly for Achilles and patellar tendinopathy. However, reporting for some tendinopathies and content items such as adherence was poor, limiting optimal translation to clinical practice.


We say that a monoid S with identity element acts on a set Q if q(st) = (qs)t and q = q. As with groups, if we set s ∼ = t whenever qs = qt for all q ∈ Q, then ∼ = is a congruence relation and S/ ∼ = acts faithfully on Q. (1) Q is a finite set (whose elements are called states), (2) S is a monoid, (3) · is an action of S on Q, (4) q 0 ∈ Q (called the starting state), and (5) F ⊆ Q (whose elements are called final states or accept states). We define the language of M as L S (M) = {s ∈ S : q 0 s ∈ F }, and say that these elements are recognized or accepted by M. If h : T → S is a homomorphism, then T acts on Q via q * t = q · h(t). Thus we obtain another DFA M = Q, T, * , q 0 , F with the corresponding language L T (M). We are particularly interested in the case when T is the free monoid generated by some finite alphabet A. We now define a nondeterministic finite automaton (NFA) with-moves and show how one can be represented as a DFA with the same language. An NFA is a quadruple N = Q, S 0 , q 0 , F where (1) Q is a finite set, (2) S 0 is a finite set of binary relations on the set Q, with a distinguished member ∈ S 0 such that ⊇ ∆ (equality), (3) q 0 ∈ Q, and (4) F ⊆ Q.


1,25‐dihydroxycholecalciferol (1,25(OH)2D3) possesses proliferation and differentiation modulating effects in many cell types in vitro. We studied the effect of 1,25(OH)2D3 on 3H‐thymidine incorporation in FRTL5 cells, a cultured rat thyroid follicular cell line. 1,25(OH)2D3 alone at 10−11 and 10−9 M exerted no effect on 3H‐thymidine incorporation. However, at 10−7 M, 1,25(OH)2D3 slightly enhanced 3H‐thymidine incorporation. In the presence of 5% calf serum, 1,25(OH)2D3 increased 3H‐thymidine incorporation induced by calf serum in a dose‐dependent manner. 1,25(OH)2D3 also enhanced 3H‐thymidine incorporation induced by PMA, an extrinsic stimulator of protein kinase C, without directly affecting PMA‐induced protein kinase C translocation. In contrast to the stimulatory effects of 1,25(OH)2D3 on the calf serum and PMA‐induced 3H‐thymidine incorporation, 1,25(OH)2D3 inhibited the increase in 3H‐thymidine incorporation induced by TSH in a dose‐dependent manner. This effect of 1,25(OH)2D3 on TSH‐induced 3H‐thymidine incorporation may be, in part, due to post‐cAMP pathways since 1,25(OH)2D3 also inhibited the increase in 3H‐thymidine incorporation induced by Bu2cAMP without affecting the TSH‐induced increase in cAMP. The stimulatory effect of insulin on 3H‐thymidine incorporation, a cAMP‐independent process, was also inhibited by 1,25(OH)2D3. We conclude that 1,25(OH)2D3 affects 3H‐thymidine incorporation in FRTL5 cells raising the possibility of a physiologic role for 1,25(OH)2D3 in the growth and function of thyroid follicular cells.


A study was conducted in the West Rosebud and Stillwater drainages of the Beartooth Mountains, southcentral Montana, during the summer of 1974 and the winter and spring of 1975 to obtain quantitative data on populations, range use, food habits and movements of bighorn sheep in these areas. Eleven major habitat types and twelve subtypes were recognized. Canopy-coverages and frequencies of occurrence were determined for low growing plant taxa in each habitat type and/or subtype. Recent trends in total numbers of bighorn sheep on both the West Rosebud and Stillwater ranges during spring appeared directly related to the numbers of lambs produced and surviving through winter. Lamb:ewe ratios were 64:100 during the summers of 1973 and 1974 on the West Rosebud, but lamb mortalities in excess of 80 percent during the subsequent winters resulted in a declining population. The Stillwater population has generally increased since 1972 with lamb:ewe ratios ranging from 41:100 to 60:100 during winter and spring. West Rosebud bighorns appeared to lamb during the last week of June and the first week of July, nearly one month later than is thought to be "normal" for bighorns. During winter West Rosebud bighorns ranged on high alpine plateaus and were restricted to small windswept areas of the Cavex/Podi h.t. where relatively little forage of low nutritional value was available. In April these bighorns migrated down to the steep valley slopes along West Rosebud Creek, dominated by the Avtv subtype (Pipo/Feid h.t.), where forage of high nutritional quality was available. Stillwater bighorns spent the winter and spring in the valley bottom using various habitat types where forage of high nutritional quality was relatively abundant. Inferior horn growth, higher lungworm larval output and high lamb mortality on the West Rosebud probably reflected these differences in range use and forage conditions on the two areas. Food habits were determined from feeding site examination and supplemented by rumen analyses. Dried forbs dominated the bighorns diet on the primary West Rosebud winter range. On the Stillwater preferred grasses comprised most of the winter diet, though forbs and browse plants were also used. Grasses dominated the spring diet on both areas. Grasses, forbs and browse was the order of importance of forage classes used by West Rosebud bighorns during summer and fall. Mule deer generally used the same habitat types as bighorn sheep on the two areas, but there was little overlap in food habits between these two species. Mountain goats generally used the same habitat types and forage species as bighorns. Food habits of horses, cattle and domestic sheep overlapped significantly with those of bighorn sheep. STATEMENT OF PERMISSION TO COPY In presenting this thesis in partial fulfillment of the require ments for an advanced degree at Montana State University, I agree that the Library shall make it freely available for inspection. I further agree that permission for extensive copying of this thesis for scholarly purposes may be granted by my major professor, or, in his absence, by the Director of Libraries. It is understood that any copy ing or publication of this thesis for financial gain shall not be allowed without my written permission.


Not the least impressive feature of the book is the skill and understanding which Mr. Korol demonstrates in relating the ideology and objectives of the Communist party to the educational system which it has fathered. In an excellent concluding chapter he emphasizes that the main features of the system originate in the ideas and objectives of the party, that this explains its centralization, its technical emphasis, its devotion more to training than to education in the broader sense of the term. Simple quantitative comparisons of the American and Soviet systems he regards as irrelevant, since &dquo;the vital elements of American education have no place in the Soviet scheme and cannot have in any communist state. To the extent that such elements distinguish education from mere training, the greatest tragedy of this century may well ultimately be that of 40 years successive generations of the Russian peoples, ... for all the training they have so eagerly and grimly undergone, have been denied the privilege of education.&dquo; On the other hand, the Soviet leaders, however we regard their conception of education, have given impressive support to the purposes of education as they conceive it. The author's concluding sentence is therefore a sobering one: &dquo;If, in the face of the Soviets' superior power to allocate the resources under their control, democracy and economic progress for all nations are to prevail, ... we free peoples must find a way to release a larger share of our aggregate resources and energy from nonessential material uses and devote them to the service of indispensable goals.&dquo;


Purpose: This study sought to analyze the relationship between public debt and financial development in Kenya. The specific objectives were to examine the association between public domestic debt and financial development, to analyze the connexion between public external debt and Kenya's financial development. The study was underpinned on Financial Repression, Financial Liberalization, Lazy Bank Hypothesis, Demand following hypothesis, and the MacKinnon theoretical model.
Methodology: The study applied positivism philosophy and explanatory research design. The study used country data hence no need for sampling. Data was collected for 1964 to 2019 from Kenya's Central Bank. Descriptive and inferential statistics were used in the study. Diagnostic tests such as Multi-collinearity, Auto-correlation, Normality, and Unit root were performed.  Specifically, the long-run and short-run relationships were analyzed using the Auto-Regressive Distributive lag (ARDL) bound test for cointegration. An error correction model was applied to examine the short-run association.
Finding: The test suggested the presence of a stable long-run relationship between financial development, public domestic debt, public external debt, and interest rate. The study finding indicates that public domestic debt has a statistically significant negative relationship with Kenya's financial development both in the long and short run. Also, public external debt has a statistically significant positive long and short-run association with financial development.
Unique Contribution to Theory, Practice and Policy: The affirms liberalization theory by Shaw and Mackinnon (1973), advocating for a reduction in direct government participation in the financial market credit restriction In addition the study's findings are consistent with the lazy bank hypothesis by Hauner (2009) In addition, the government must ensure appropriate market-determined interest rate must be applied in domestic public debt. Furthermore, the government should continue fostering financial liberalization policies that encourage public external debt has its impacts positively on financial development.


Objective To observe the clinical effects of combined application of diethylstilbestrol and naproxen suppositories for removing IUD in postmenopausal women.Methods A total of 104 postmenopausal women required to remove IUD were randomly divided into two groups.Patients(n=59) in observation group were given with diethylstilbestrol and naproxen suppositories before removing IUD while patients(n=45) in control group were not given with drug.Results The rate of softening of cervix,analgesic effect and result of removing IUD were compared between these groups,all these parameters in observation group were better than those of control group.There was significant difference between them(P0.05).Conclusion The combined application of diethylstilbestrol and naproxen suppositories can get satisfactory effect in improving dilation and softening of cervix for removal of IUDs in postmenopausal women.


A general theory of action provides, first, a notation in which the effects of possible individual acts can be expressed and, second, a method for probability calculations of the dynamics of systems of interacting actors; this article develops the foundation for such a theory.

A framework is presented, which allows the effects of human actions to be described. The presentation is sufficiently general that other kinds of event can also be accommodated.

The framework uses a simple system of modal logic, with five axioms, to define what is meant by an effect of an event or act at any level of living system or in nonliving systems. It is proposed that, in empirical studies, the significant types of act and event should be characterized by listing their effects in the notation which the framework provides.

The application of the framework to human acts is described; and a diagrammatic method to represent the effects of these acts is given. It is shown that there are eleven fundamentally different possible relationships between acts and their effects.

For each of the eleven basic kinds of effect, an approximate formula is given to relate the expected frequency of that effect to the overall characteristics of a state of affairs within a system.

The use of the framework to draw global conclusions from local information is illustrated by showing how approximate population densities may be calculated from mechanisms for birth and death described in terms of the framework.


Psychopathology can be studied from a scientific or artistic perspective. While there are important differences between the two perspectives, similarities also exist. Recognition of these similarities and differences provides a treatment of psychopathology different than that provided by either perspective alone. The classification by the sciences of psychology and psychiatry and the art-form motion picture genre called film noir is discussed. Film noir was chosen because, like psychology and psychiatry, psychopathology plays a central role, and it is presented in a cohesive and consistent manner. Classification is discussed in the context of the Diagnostic and Statistical Manual of Mental Disorders (DSM). If film noir is classified according to DSM, it can be seen that film noir presented almost all of the classes of psychopathology and many of the categories, as well as several other important aspects about psychopathology.


Female goats at mid luteal phase were passive immunized against inhibin α subunit to determine the roles of inhibin in regulation of secretion of FSH, LH, P, and E 2 in goats. Twelve Japanese Shiba female goats at luteal phase were injected with PGF 2α (2 mg/goat) and showed estrous behavior 3 5 days after injection. Then the goats were divided into two groups with six goats for each. In the experimental group, each goat was injected i.v. at d10 (d0=the day estrus begin) with 20 mL of antiserum raised in castrated male goats against inhibin α subunit (INH AS) and blood samples were collected at immediately before and 6, 12, 24, 48, 72, 96 and 120 h after injection of INH AS. In the control group, goats were injected with control serum and blood samples were collected at the same time intervals as in the experimental group. All blood samples were treated with heparin as anticoagulant and plasma was separated. FSH, LH, P and E 2 concentrations in plasma were measured by RIA. Results showed that FSH concentration increased significantly and reached a peak level at 12 h and high level maintained until 96 h after injection of INH AS. But LH concentration did not change after injection of INH AS. Progesterone level increased till 72 h but then decreased dramatically. E 2 concentration increased dramatically 96 h after injection of INH AS. These results indicate that inhibin plays a key role in regulation of secretion of FSH and affect the secretion of progesterone and oestradiol.


A wind tunnel test was conducted to characterize the aeroacoustic environment of several configurations of the Space Launch System during ascent. The test was conducted in the 11-by-11 foot transonic and 9-by-7 foot supersonic test sections at NASA Ames research center. Throughout this experiment data was collected from several types of instrumentation including: dynamic and steady-state pressure sensors, unsteady and steady pressure sensitive paint, time-resolved shadowgraph and infrared imaging. The following details results and analysis from the time-resolved shadowgraph and infrared imaging data systems. The time-resolved shadowgraph provided a qualitative measurement of the near-field turbulent fluctuations. These results helped provide context to the relative magnitude and frequency content of the fluid-structure-interaction driving the surface pressure phenomena characterized by the discrete pressure transducers and unsteady pressure sensitive paint. The infrared imaging was used to verify boundary layer trip effectiveness and provide temperature correction for the unsteady pressure sensitive paint.


It mainly introduces collecting heat supply thermal power station control system PID collecter parameter setting using MATLAB programe making and simulink danamic imitation experiment.


Background: Antibiotics are important in the management and prophylaxis of infections in patients at a risk of experiencing microbial disease. Uses of systemic antibiotics in dentistry are limited since management of acute dental conditions is primarily based upon extraction of teeth or extirpation of the pulp. However, the literature provides evidence of inappropriate prescribing practices by practitioners, due to a number of factors from inadequate knowledge to social factors. Aim: The aim was to assess the therapeutic prescription of antibiotics in the dental office. Materials and Methods: In the current study, 42 faculty members of two dental colleges in the same vicinity were included. A questionnaire was drafted and sent to the dentists to collect data pertaining to the conditions in which antibiotics were prescribed and most commonly prescribed antibiotic. Results: During the study period, 42 faculty members from various departments in the institutes were surveyed, of which 41 questionnaires were completely filled. Amoxicillin was the most commonly prescribed antibiotic followed by other amoxicillin combinations; Metronidazole was most widely prescribed antibiotic for anaerobic infections. Conclusion: We have entered an era where cures may be few due to increasing microbial resistance. The biggest force for change will be if all practicing dentists looked at their prescribing and made it more rational.


Many pathogens exploit host cell-surface glycans. However, precise analyses of glycan ligands binding with heavily modified pathogen proteins can be confounded by overlapping sugar signals and/or compounded with known experimental constraints. Universal saturation transfer analysis (uSTA) builds on existing nuclear magnetic resonance spectroscopy to provide an automated workflow for quantitating protein-ligand interactions. uSTA reveals that early-pandemic, B-origin-lineage severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike trimer binds sialoside sugars in an "end-on" manner. uSTA-guided modeling and a high-resolution cryo–electron microscopy structure implicate the spike N-terminal domain (NTD) and confirm end-on binding. This finding rationalizes the effect of NTD mutations that abolish sugar binding in SARS-CoV-2 variants of concern. Together with genetic variance analyses in early pandemic patient cohorts, this binding implicates a sialylated polylactosamine motif found on tetraantennary N-linked glycoproteins deep in the human lung as potentially relevant to virulence and/or zoonosis. Description Glycans in the spotlight Viral infection of a cell requires a complex series of molecular recognition events, often mediated by glycoproteins and cell-surface glycans. Buchanan et al. developed a nuclear magnetic resonance analysis method to better study such interactions and applied it to influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins binding sialoside glycans. For SARS-CoV-2 in particular, they found evidence for a sialoside-binding site in the N-terminal domain of the original B-origin lineage spike protein that was lost in subsequent variants. These results were corroborated by cryo–electron microscopy structures of the glycan-bound spike protein and genetic variation analysis from patients early in the pandemic, which uncovered host factors involved in glycosylation that potentially contributed to variation in disease severity. —MAF A multidisciplinary study of viral proteins uncovers binding sites and patterns for sialoside glycans. INTRODUCTION The surface proteins found on both pathogens and host cells mediate cell entry (and exit) and influence disease progression and transmission. Both types of proteins can bear host-generated posttranslational modifications, such as glycosylation, that are essential for function but can confound current biophysical methods used for dissecting key interactions. Several human viruses (including non-SARS coronaviruses) attach to host cell surface N-linked glycans that include forms of sialic acid (sialosides). There remains, however, conflicting evidence as to whether or how SARS-associated coronaviruses might use such a mechanism. In the absence of an appropriate biochemical assay, the ability to analyze the binding of such glycans to heavily modified proteins and resolve this issue is limited. RATIONALE We developed and demonstrated a quantitative extension of "saturation transfer" protein nuclear magnetic resonance (NMR) methods to a complete mathematical model of the magnetization transfer caused by interactions between protein and ligand. The designed method couples objective resonance identification and intensity measurement in NMR spectra (via a deconvolution algorithm) with Bloch-McConnell analysis of magnetization transfer (as judged by this resonance signal intensity) to enable a structural, kinetic, and thermodynamic analysis of ligand binding. Such quantification is beyond previously perceived limits of exchange rates, concentration, or system and therefore represents a potentially universal saturation transfer analysis (uSTA) method. RESULTS In an automated workflow, uSTA can be applied to a range of even heavily modified protein systems in a general manner to obtain quantitative binding interaction parameters (KD, kEx). uSTA proved critical in mapping direct interactions between sialoside sugar ligands and relevant virus surface attachment glycoproteins, including multiple variants of both severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and influenza H1N1 hemagglutinin protein. It was successful in quantitating ligand NMR signals in spectral regions otherwise occluded by resonances from mobile protein glycans. In early-pandemic (December 2019) B-origin-lineage SARS-CoV-2 spike trimer, a clear "end-on" binding mode of sialoside sugars to spike was revealed by uSTA. This mode contrasted with "extended-surface side"-binding for heparin sugar ligands. uSTA-derived restraints used in structural modeling suggested sialoside-glycan binding sites in a β sheet–rich region of spike N-terminal domain (NTD), distant from the receptor-binding domain (RBD) that binds ACE2 co-receptor and that has been identified as the site for other sugar interactions. Consistent with this NTD site being a previously unknown sialoside sugar-binding pocket, uSTA-sialoside binding was minimally perturbed by antibodies that neutralize the ACE2-binding RBD domain. Strikingly, uSTA also shows that this sialoside binding is disrupted in spike from multiple variants of concern (B1.1.7/alpha, B1.351/beta, B.1.617.2/delta, and B.1.1.529/omicron) that emerged later in the pandemic (September 2020 onward). Notably, these variants possess multiple hotspot mutations in the NTD. End-on sialoside binding in a B-origin-lineage spike-NTD pocket was pinpointed by cryo-EM to a previously unknown site that is created from residues that are notably mutated or are in regions where mutations occur in variants of concern (e.g., His69, Val70, and Tyr145 in alpha and omicron). An analysis of beneficial genetic variances correlated with disease severity in cohorts of patients from early 2020 suggests a model in which this site in the NTD of B-origin-lineage SARS-CoV-2 (but not in later variants) may have exploited a specific sialylated polylactosamine motif found on tetraantennary human N-linked glycoproteins, known to be present in deeper human lung. CONCLUSION Together, these results confirm a distinctive sugar-binding mode mediated by the unusual NTD of B-origin-lineage SARS-CoV-2 spike protein that is lost in later variants. This may implicate modulation of binding by SARS-CoV-2 virus to human cell surface sugars as a determinant of virulence and/or zoonosis. More generally, because cell surface glycans are widely relevant to biology and pathology, the uSTA method can now provide ready, quantitative, widespread analysis of complex, host-derived, and posttranslationally modified proteins in their binding to putative ligands, which may be relevant to disease, even in previously confounding complex systems. uSTA identifies a sugar-binding site and pose in the unusual NTD of early-pandemic SARS-CoV-2 spike. (A) This site and pose, which were confirmed by cryo–electron microscopy, are heavily mutated in variants of concern. (B) Analyses reveal a loss of sialoside-spike binding, rationalized by clustering of mutations around the binding site. *All alpha-variant mutations are in >1 variant.


Introduction:
 RV dysfunction and failure is a common consequence of pressure overload associated with all types of pulmonary hypertension. Metabolic and mitochondrial structure and function alterations are further associated with RV dysfunction and failure. Mitochondrial respiratory supercomplexes (mSC) are physically associated assemblies of electron transport chain (ETC) complexes I, III, and IV which are thought to promote improved bioenergetic capacity and efficiency. We previously found reductions in mSC in animal models of PH. It is currently unknown if mSC are reduced in human right ventricle with PH and RV dysfunction.

 Methods:
 Failing hearts were harvested from patients at the time of transplant (n=20). Sample from the RV were frozen and later mitochondrial isolated and solubilized for Clear-native PAGE (CN-PAGE) to determine complex IV activity. Gels were normalized to Coomassie stained protein via far-red imaging. mSC activity was determined as amount of active CIV in the SC region (>1mD). Only patients with a recent right heart catheterization prior to transplant were used for correlation analysis. Pulmonary artery pulsatility index (PA systolic pressure-PA diastolic pressure/ right atrial pressure (PAPi)) and right atrial pressure to pulmonary capillary wedge pressure (RAP:PCWP) were used as indicators of pulmonary right ventricular dysfunction.

 Results:
 The majority of patients displayed high mPAP, however PH with RV dysfunction is associated with high mPAP and RAP:PSWP and low PAPi while high mPAP, low RAP:PSWP, and high PAPi indicate PH with normal or preserved RV dysfunction. SC activity as measured as CIV activity in SC region positively correlated with PAPI, (r=.6, P=.004) and negatively with RAP/PCWP (r=
 -
 .57, P=.009). There was no correlation with non-SC CIV activity as measured by CN-PAGE.

 Conclusion:
 The severity of RV dysfunction in humans with Group II PH is correlated with reduction in activity of mSC in RV mitochondria


The 5th and final assessment of the 12-month longitudinal study was conducted in July 2014. The IMCF impact survey commenced in August and is expected to be completed in early September 2014. The 5th and final assessment of the longitudinal study was carried out in August 2014. The IMCF impact survey is expected to start in midSeptember 2014. Agricultural input trade fairs were conducted in all nine target districts of Otdar Meanchey (OMC) and Preah Vihear (PVR) provinces in May and June 2014, with over 7,000 attendants. A second group of nutrition education sessions commenced in the 34 villages from phase 1 with a total of 443 caregivers. Highlights of food security and nutrition education interventions No.7 September 2014


1 ABSTRACT This paper deals with the development and identific a on of urban zones, which used to function as a transition zone between the historical city and the outskirts. Usually these zones contained functions like car dealers, supermarkets, hardware stores, workshops, etc.. In summary these functions have in common tha t they need space and good connectivity, while their location nearby to the city was also of importance . During the last 20 years and encouraged by rising d emand the pressure has increased on centrally locat ed areas and plots, and forced a change of usage in th ese transition zones towards functions which are mo re profitable.


The decay signal of AT and Ax emissions in KBr: Tl is studied in the temperature range 80 to 300 K. A complex decay with three time constants is observed for both the emissions. The experimental results of the lifetimes and intensities versus temperature are explained with a single model for AT and Ax emissions.

On a etudie dans le systeme KBr: Tl la decroissance de la luminescence dans l'intervalle de temperature 80 a 300 K, pour l'emissions AT et AX. Le signal de decroissance de la luminescence est complexe; il est compose de trois composantes avec differentes valeurs de la vie moyenne pour l'emission Ax et aussi pour l'emission AT. L'allure – en function de la temperature – de l'intensitye (des composantes de la vie moyenne) et des vies moyennes a ete explique avec un unique modele pour les emissions AT et AX.


A method has been worked out for correcting distortions which affect the apparent shape of a continuous $\ensuremath{\beta}$-ray spectrum. Internal conversion lines are studied in the $\ensuremath{\beta}$-spectrometer and found to have a finite width and in the case of 180\ifmmode^\circ\else\textdegree\fi{} focusing an unsymmetrical shape.