In order to estimate energetic relationship, microphytic and benthic bivalve levels of a shallow (1.5 m), sandy ecosystem near Marseille (Gulf of Fos, Southern France) were sampled monthly during 1.5 year, in two sites differing by their wave exposure. In the sheltered area, the bivalve Ruditapes decussatus was the dominant species, while another bivalve, Donax trunculus, was found in the open, wave exposed site. Chlorophyll a and primary production of the phytoplankton and the microphytobenthos, as well as population dynamic, growth and biochemical composition of bivalves (lipids, proteins and carbohydrates) were monitored. Assessments of functional chlorophyll a and pheopigments were made before and after acidifying the acetonic extracts. Primary production was estimated using


This study analyses Ignatius' practice and understanding of mortification and discernment in his Autobiography. It notes a shift in focus as Ignatius learns to discern - from internal to external, from personal to communal, and from subjectivity to objectivity. It also notes a shift in the focus of his motivation for mortification - from self-hatred to penance to a more discerned and moderate practice of mortification for mission. The study also show the ways in which mortification and discernment became more inter-connected.


During this work i'll talk about two famous models in epidemiologe, SIS and SISV models.
Starting with a system of coupled differencial equations, that will describe each model
dynamics, analitical and numerical solutions will be searched. We then proceed to compare
this solutions with different sorts of simulation results.
I'll be studying situations where we should've the presence of a phase transition, enriching
our analysis close to those critical points. In this case, we will engage our efforts in
comprehending the behave of the model dynamics. Given such circumstances of a system
in criticality, let us extract some critical exponents that will be of much value to elucidate
our understanding.
Lastly, keeping in mind that this work is in the realm of physics, after we pull out every
data and simulation relative to the models, I'll be always trying to provide interpretations
about obtained results.


This report is intended to be a primer on the characteristics that affect the design, use and operations of changeable message signs (CMSs), and to provide guidance on the selection of the appropriate type of CMS display. Guidelines on the selection and design of CMS messages are presented in a companion Report No. FHWAjTX-92/1232-10 entitled, "Guidelines on the Selection and Design of Messages for Changeable Message Signs•.


Proper names have meaning,including very possibly naming meaning and feature meaning,etc.The referential theory of meaning does not apply in the case of proper names.Translated proper names,on the other hand,might contain individual and general translational meaning as well as the meaning the SL names have already had.Translation,as it creates and bestows meaning,is an independent act of creativity and a process of meaningful behavior.


Introduction: one problem faced in many hospitals and public health services is to select the drugs that will be part of the therapeutic arsenal of these institutions. This way, an appropriate and rational method of selection of these drugs is required. The drug screening a routine minimizes the subjectivity and enables a decision-making effectiveness maximum, thus reducing the use of resources, with a higher quality of pharmacotherapy at the lowest cost. Objective:The aim of this study was to evaluate the applicability of Multiattribute Utility Theory (MAUT) as a method able to analyze systematically and quantitatively medicines considering several different factors at the same time and which may be useful in drug screening in hospitals. Methodoly: heparins were chosen for this evaluation because of the diversity of existing variables on the use of unfractionated heparin and low molecular weight. Heparins were evaluated through literature review, aiming to identify useful variables that define their use as anticoagulants and antithrombotics. The variables were measured and analyzed using the multi-attribute decision model and developed in 10 phases. The attributes selected were: effectiveness, cost, safety, and experience with the drug and convenience


Scholars and journalistic accounts have devoted growing interest to the centralizing trends characterizing platforms and the "platform society." They often oppose this model to the alleged openness, horizontality, and "equality" they attach to "networks." Such depictions seem willing to give up on a thorough consideration of network structure, which appears nowadays less fundamental to reflect on the digital world (and society) than it was 25 years ago. Or even question whether the network society model, as proposed by Castells, is unsuitable for describing contemporary society. In our opinion, the dichotomy opposing the (alleged) openness and egalitarian nature of networks (and of the network society), to the current centralization trends characterizing the platform society, as well as the subsequent assumption that networks are an outdated heuristic tool, derive from a misunderstanding of networks' structure and dynamics. Scholars have shown that the structure of most complex networks can be defined as "scale-free," following a power-law distribution. Complex networks, indeed, show the tendency for some nodes to become more interconnected than others (thus becoming "hubs"). In this, the understanding of network structure proposed in Castells (1996), contrary to the rhetoric considering networks intrinsically as "egalitarian," is still a conceptual and analytical tool of the utmost importance for understanding the so-called "platform society." This paper focuses on networks, network models, and the network society, reviewing what was proposed in Castells (1996). We argue that the social and platform ecosystem we are witnessing today can be understood from the perspective of scale-free networks and is, indeed, consistent with the premises provided in 1996. When observing networks, we address both structure and agency, and both the macro (network morphology) and micro (networked individualism and sociability) levels


Community welfare is one of the goals expected by each region including in Padangsidimpuan city. Based on data obtained the amount of poverty in Padangsidimpuan city experienced fluctuations from 2008 to 2015. The formulation of the problem in this study is whether there is an effect of the effectiveness of village fund management on improving the welfare of rural communities in Padangsidimpuan city. Does the manager's religiosity behavior moderate the influence of village fund management by increasing the welfare of rural communities in Padangsidimpuan City? This type of research is causality research using quantitative data. The population of this study is the village community in the city of Padangsidimpuan with a total of 41 villages. Given the limitations of the author, the sample in this study was taken by 5 people from each village, namely 5 x 41 villages = 205 villagers. Data collection techniques used were questionnaires and data analysis conducted with Smart PLS. Based on the results, it was found the value of the village fund management pathway affected the welfare of the village community of 5.875 with a probability value of 0.024. Because the t-count value (5.875) is greater than critical t (1.96) at the 5% error rate, it can be concluded there is an effect of the effectiveness of village fund management on improving the welfare of rural communities in Padangsidimpuan City. And the t-count value of the manager's religiosity behavior trends moderates the relationship of village fund management to rural community welfare of 0.458 with a probability value of 0.031. Because the t-count (0.458) is greater than the critical t (1.96) at the 5% error rate, it can be concluded that the manager's religiosity behavior can moderate the relationship between village fund management and the improvement of the welfare of rural communities in Padangsidimpuan City.


The estimation of Terizidone in pharmaceutical dosage form by using High Performance Thin Layer Chromatography was done using CAMAG HPTLC system. The separation was achieved using precoated silica gel 60 F 254 aluminium plates with mobile phase Toluene: n-Butanol 9:1 ml % v/v at wavelength 268 nm. The linearity range was found between 50-300 ng/ml-band having correlation coefficient 0.997. The recovery study of method showed the recovery between 99.3-101.6%. The LOD and LOQ values for method were 0.981 and 2.973 respectively. The R.S.D. of precision study was less than 2. The method parameters were validated as per ICH guidelines. The forced degradation studies revealed that the drug found stable in acidic, thermal and photo degradation. The LC-MS/MS study of degraded products gave the idea about the fragmentation patterns of degraded products.The developed method can be used for routine analysis of Terizidone and its formulations.


The concentration of vacancies (for the growth rate V over the critical value Vt) and of self-interstitials (for V<Vt) incorporated into growing silicon crystals is obtained numerically by solving the axial diffusion problem for fast-recombining point defects. An analytical solution is obtained for the important near-critical case. A simple but quite precise interpolation expression is found. The critical growth rate Vt for the changeover from interstitial to vacancy incorporation is proportional to the near-interface temperature gradient G0 even if the axial profile of the gradient, G(z), is of considerable nonuniformity. The experimental critical ratio V/G0, together with the observed amount of vacancies in voids, provides a good estimate for the interstitial self-diffusional product at the melting point, 3×1011 cm−1 s−1, in accord with reported data.


In this paper,a brief introduction of cloud computing and cloud security is given firstly,and considerations about the architecture of cloud security are discussed.Then,two kinds advanced architectures of cloud security are introduced and key technologies of cloud security are analyzed.


This experiment showed that mutagenicity of fly ash derived from different coal conversion technologies, as determined by the Ames plate incorporation test, was similar in all three laboratories. The differences in mutagenic activity of each fly ash between laboratories with different solvent extraction methods were no greater than one order of magnitude. In addition, there were much smaller, but still significant differences in mutagenic activity between laboratories when the same solvent extract of a particular fly ash was tested in each laboratory. There were also significant differences in mutagenicity of the positive control mutagen (maximum of fivefold) between laboratories. Because of this difference in Ames test sensitivity between laboratories, the influence of the solvent extraction methods on differences in mutagenicity was not clear. However, the data suggested that either there were significant differences in the degree of sensitivity of Ames tests for different complex mixtures within each laboratory, or else there were differences in mutagen extraction efficiency between different solvent extraction methods. Both Ames test sensitivity and solvent extraction may be important. Further work would be necessary to separate the contribution of these two factors. An important aspect of further work would be to separate the contribution of the innatemore » sensitivity of substrains of Ames tester strains in each laboratory from the possible effects of differences in Ames testing methodology. This could be done by testing the same extracts of fly ash and positive control mutagens with substrains of tester strains exchanged between laboratories. This work also implies that caution should be exercised in assuming that the same solvent would have the same efficiency for extraction of mutagens from different fly ashes even within the same laboratory.« less


Bacteriological evaluation of contact surfaces (counters, chairs/benches, railings, poles, tables and door handles of rest rooms) at selected bus terminals in Uyo metropolis was carried out using standard procedures. Counters and poles revealed highest (log10 6.3 ± 0.7CFU/cm2) and least (log10 1.5±0.3 CFU/cm 2 ), total heterotrophic bacterial counts respectively. Bacterial isolates associated with the contact surfaces included Staphylococcus aureus, S. epidermidis, Escherichia coli and species of the genera Bacillus, Micrococcus, Streptococcus, Proteus, Pseudomonas, Klebsiella and Serratia. Bacillus sp (16.6%) and Serratia sp (2.8%) revealed highest and least frequency distribution among the isolates. The Gram positive bacteria associated with the contact surfaces showed highest susceptibility (93%) to erythromycin and least susceptibility (12.2%) to augmentin while the Gram negative bacteria revealed highest (92.3%) and least (13.8%) susceptibility to ofloxacin and augmentin respectively. This study has revealed that contact surfaces at bus terminals can harbor potential pathogenic microorganisms hence adequate and regular sanitation practices should be embraced by staff and travelers at these places to avoid possible health risk.


Monitoring is an important component of internal control system,but the component has been heavily influenced by bureaucracy management mode,so it is entirely inelastic based on assignment.Coming of knowledge economy,knowledge management mode becomes more and more important,which shakes the basement of bureaucracy management.The management mode affects the internal control,and there are many differences between knowledge management and bureaucracy management,which take great changes for the monitoring component.Firstly,the component will not be a single one,but a part of control activity component. Secondly,lasting monitoring will focus on key activities in teamwork instead of specific tasks.Thirdly,the adaptability will be the main evaluation of internal control instead of rationality and effectiveness.Fourthly,the knowledge audit will become an important part of internal audit.


The subject of the research is the scientific and technological cooperation of countries within the framework of an integration association based on the EU case study. The purpose of the research was to identify the main vectors of the coordinated scientific and technological policy of the EU with a focus on the feasibility of its application to the EAEU practices to enhance business activities of enterprises in solving their own tasks. The experience of the EU countries in the implementation of scientific, technological and innovation policies made it possible to formulate a number of principles, methods and tools that can be used in the EAEU practices. It is concluded that in terms of the achievements considered herein, the foreign practice can be useful taking into account challenges faced by countries and companies when solving common problems, and will help avoid errors in making decisions. Based on the European experience of shaping a general scientific, technological and innovation policy, it is proposed to apply the EU experience to the practical activities of the EAEU member states.


The present work is designed to investigate the concentrations of heavy metals (Cr, Mn, Fe, Co, Ni, Cu, Zn, Cd, and Pb) and physico-chemical properties including pH, conductivity, salinity, total dissolved solid (TDS), dissolved oxygen (DO), and specifi c gravity that were analyzed in fresh bovine milk samples sold in various towns of District East, Karachi. Statistical techniques, including cluster analysis and principal component analysis (PCA), were performed to organize the recorded data in such a way as to expose the internal structure of multivariate data matrix. Results of PCA revealed that conductivity, salinity, and TDS possessed strong relationships with each other. The levels of heavy metals were assessed by atomic absorption spectroscopy (AAS). The mean concentrations of Cr, Mn, Fe, Co Ni, Cu, Zn, Cd, and Pb were assessed as 0.001-0.232 mg/l, 0.001-0.460 mg/l, 0.001-3.260 mg/l, 0.001-0.108 mg/l, 0.001-0.122 mg/l, 0.001-0.098 mg/l, 2.086-5.498 mg/l, 0.001-0.053 mg/l, and 0.001-1.428 mg/l, respectively. Remarkable numbers of samples were found to be contaminated with Cd and Pb and exceeded the tolerable guidelines


Multiple-wavelength vertical-cavity surface-emitting laser (VCSEL) arrays are fabricated using a location-resolvable in situ optical calibration method and a patterned-substrate growth technique in a molecular beam epitaxy (MBE) system. The high and low wavelength limits are achieved within 0.28% accuracy and with a 2.66 A wavelength standard deviation from 4 × 35 arrays.


MathEdit (Su et al., 2006) is a browser-based tool implemented in JavaScript that provides a convenient and intuitive graphical user interface for creating and editing mathematical expressions as well as a well-defined API for interoperating with its containing Web page. MathEdit can produce MathML Content and Presentation Markup as well as infix expressions for Web applications. The results returned can be displayed in a Web page or used in further computations. Here, we describe the methods of expression editing, visual navigation, and the MathEdit API. We also present the actual use of MathEdit in such interactive Web applications as curve plotting and Math-capable BBS.


Semaphorins (sema) constitute a family of molecules sharing a common extracellular domain (semaphorin domain). This family includes several types of secreted and membrane‐associated molecules that are grouped into eight subclasses (subclasses 1–7 and viral semaphorins). Subclass 3 semaphorins are secreted molecules involved in axonal guidance, mainly through repulsive gradients and induction of growth cone collapse. More recently sema 3 molecules have been identified as positive factors in dependence of the type of neurons. Besides their axonal guidance function, some semaphorins have been implicated in apoptosis and survival. We investigated the effect of sema3C on survival and neurite outgrowth of rat cerebellar granule neurons (CGNs) in culture. 3T3 cells were stably transfected with sema3C. Several clonal lines were established and tested for their neuritogenic activity and one, S3C‐8, was selected for the bulk of experiments. S3C‐8 was co‐cultured with CGNs. Sema3C enhanced CGN viability as assessed in co‐cultures of CGNs with monolayers of S3C‐8 in comparison with co‐cultures of CGNs with control mock‐transfected 3T3 cells. Moreover sema3C induced neuritogenesis of cultured CGNs, which express neuropilin‐1 and ‐2. S3C‐8 cells, overexpressing sema3C, were significantly more neuritogenic for CGN than poly l‐lysine (PLL), a positive substrate for CGNs, as assessed by the measurement of the length of neurites and confirmed by Tau expression along the time of culture. CGNs co‐cultured with S3C‐8, showed up‐regulation of the expression of axonal microtubule‐associated proteins (MAPs) such as Tau, phosphorylated MAP2C and mode I‐phosphorylated MAP1B compared with neurons cultured on control 3T3 cells. We also found increased expression of a specific marker of neuronal cell bodies and dendrites, high molecular weight MAP2 (HMW‐MAP2). Interestingly, there was no accompanying up‐regulation of a marker enriched within the neuronal somatodendritic domain, mode II‐phosphorylated MAP1B. These data support the idea that secreted sema3C favors survival and neuritogenesis of cultured CGNs.


Abstract: Composing from sources may no longer be the exclusive domain of reading-to-write activities. The ever-increasing presence of video technology and broadcasting in academic settings could place listening-to-write tasks on a similar footing. This article describes a listening-to-write task, the video-based short comment, which (1) uses video as linguistic input, (2) honors the current upsurge of skills integration, and (3) draws on a particular view of critical thinking. The teaching context, procedure, material design, guidelines for teachers, video-based short comment samples, and student strategies round up the task description. The article aims at making a good case for the task by noting its promises and limitations and includes a preliminary research agenda. Key words: assessment, critical thinking, listening-to-write tasks, reading-to-write tasks, skills integration Language: Relevant to all languages Introduction Enthusiasm for constantly reevaluating ideas in English as a foreign language (EFL) instruction and assessment shows no signs of waning. Skills integration (i.e., reading-to-write, listening-to-talk, listening-to-write, etc.) is once again making its mark in this field as well as in the greater picture of applied linguistics. After a peak during the early years of communicative language teaching methodologies, a short-lived slump followed. However, by the turn of the century, integration of language skills appeared to have resurfaced in methodologies such as Content Based Instruction (CBI). Indeed, one of the tenets of CBI is to champion integrated-skills tasks "because this is how skills are generally involved in the real world" (Richards & Rodgers, 2001, p. 208). It seems hardly an accident that skills integration appears also to have won over the hearts of those involved with language testing and assessment, as shown by the decision of the new Test of English as a Foreign Language (TOEFL), which is called TOEFL iBT, to include integrated-skills tasks. In fact, the Educational Testing Service currently is informing the general public that the TOEFL iBT will include new integrated tasks that will specifically "ask test takers to (a) read, listen, and then speak in response to a question; (b) listen and then speak in response to a question; (c) read, listen, and then write in response to a question" (ETS, 2005, p.1). Within this renewed interest in skills integration, the reading-to-write skill is clearly the most investigated and the most familiar to teachers. In fact, a growing trend that became visible in the early 1990s has continued to expand on the pedagogical and theoretical front (see Grabe, 2001; Ruiz-Funes, 1999). In contrast, research on listening-to-write tasks seems practically nonexistent, with very little attention being paid to the wide range of possible activities that can be designed with recorded video broadcasts as linguistic input. This is clearly at odds with the much-praised and already widespread use of video in instruction in EFL and English as a second language classrooms. Hence, this article addresses a listening-to-write task, the video-based short comment, with the aim of justifying its use by noting its promises and limitations and by presenting a preliminary research agenda. The Teaching Context: The English Learning Center I accepted a commission to design a technology-enhanced English learning environment for 429 high school EFL students in Caracas, Venezuela. Booths with computers and video recorders were installed in a large, air-conditioned room labeled The English Learning Center. Along with a colleague, I designed listening comprehension materials for work with computers, video recorders and TV sets, satellite television, and DVDs. A typical set of materials included a video segment and an exercise worksheet with its corresponding answer key. These materials provided approximately 270 hours of self-directed learning to nine classes in the last three levels of the Venezuelan high school system. …


Here on the table is a complete line of the standard enclosed fuses adopted by the Underwriters National Electric Association. The collection shows clearly what has been accomplished in regard to interchangeable features. Instead of this one table half covered with fuses, it would have required at least five such tables to hold all the enclosed fuses of these exact capacities which were in the market a year ago. Thus the number of fuses has been reduced about nine-tenths. To make all enclosed fuses of any given capacity interchangeable in the cut-outs, regardless of the make or date or place of purchase, was the object constantly in view, so that they might be as interchangeable, for example, as ordinary standard pipe-fittings. In order to make the cartridge type of enclosed fuse as interchangeable as possible in the Edison plug cut-out, which was adopted as part of the standard, fuse casings have been made which will receive the cartridge fuses, and can then be screwed into the plug cut-out. With these cut-outs thus equipped with casings, it is certain that the standard cartridge fuse, up to 60 amperes, at 250 volts, will go into either of the standard cut-out bases.


The purpose of this study was to evaluate potato clones previously selected for heat tolerance as to choose the most adapted and stable ones for use as pare...


In recent years, High-G MEMS accelerometers have been widely used in aviation, medicine, and other fields. So it is extremely important to improve the accuracy and performance of High-G MEMS accelerometers. For this purpose, we propose a fusion algorithm that combines EMD, wavelet thresholding, and temperature compensation to process measurement data from a High-G MEMS accelerometer. In the fusion algorithm, the original accelerometer signal is first decomposed by EMD to obtain the intrinsic mode function (IMF). Then, sample entropy (SE) is used to divide the IMF components into three segments. The noise segment is directly omitted, wavelet thresholding is performed on the mixing segment, and a GA-BP performs temperature compensation on the drift segment. Finally, signal reconstruction is implemented. Later, a comparative analysis is carried out on the results from four models: EMD, wavelet thresholding, EMD + wavelet thresholding, and EMD + wavelet thresholding + temperature compensation. The experimental data show that the acceleration random walk change from 1712.66 g/h/Hz0.5 to 79.15 g/h/Hz0.5 and the zero-deviation stability change from 49275 g/h to 774.7 g/h. This indicates that the fusion algorithm (EMD + wavelet thresholding + temperature compensation) not only effectively suppresses the noise of high-frequency components but also compensates for temperature drift in the accelerometer.


Partial table of contents: BASIC SCIENCE. Free--Radical Polymerization (P. Lovell). Features of Emulsion Polymerization (M. El--Aasser & E. Sudol). Stabilization of Polymer Colloid Dispersions (R. Ottewill). THEORY. Harkins, Smith--Ewart and Related Theories (A. Dunn). Modelling Rates, Particle Size Distributions and Molar Mass Distributions (R. Gilbert). PRACTICE. Formulation Components (A. Klein & E. Daniels). Batch and Semi--batch Processes (P. Lovell). Control of Particle Morphology (V. Dimonie, et al.). Process Modelling and Control (F. Schork). Latex Polymer Characterization (A. German, et al.). The Formation and Properties of Latex Films (M. Winnik). MAJOR INDUSTRIAL USES. Diene--based Synthetic Rubbers (D. Blackley). Vinyl Acetate Polymerization (G. Vandezande, et al.). RELATED HETEROGENEOUS POLYMERIZATION. Miniemulsion Polymerization (E. Sudol & M. El--Aasser). Inverse Emulsion and Microemulsion Polymerization (F. Candau). Indexes.


Forty six pea genotypes were evaluated for thirteen morphological characters during Rabi season, 2010 at Sher-e-Bangla Agricultural University, Dhaka, Bangladesh. Analysis of variance (ANOVA) test revealed significant differences among the genotypes for all the traits. Days to first flowering, plant height, branches plant , pod length, hundred seed weight, pods plant , seeds plant and seed yield plant exhibited that they 1 1 1 1 were controlled by additive gene action and selection for the improvement of these traits would be rewarding. The phenotypic variance was higher than the corresponding genotypic variance for all the characters. All the characters showed moderate to low phenotypic and genotypic coefficient of variation. Genotypic coefficient of variation was the highest for hundred seed weight (37.24) followed by number of branches plant (15.96) 1 and seeds plant (15.27). Hundred seed weight had the highest heritability (95.97). Pod length, hundred seed 1 weight, pods plant and seeds plant showed significant positive genotypic and phenotypic correlation with 1 1 seed yield. In path analysis, plant height, internode length, hundred seed weight, number of seeds pod and 1 seedsplant showed positive direct effect on yield. Considering genetic variability, correlation and path 1 analysis, emphasis should be given on pod length, seeds pod , seeds plant and hundred seed weight during 1 1 breeding program to improve seed yield of pea.


Annotation. Exacerbation and aggravation of psoriasis increases the chances of neurosis, depression, can significantly impair mental health through social stigma and leads to social isolation and maladaptation, a significant reduction in quality of life. Studying this problem from the standpoint of comparative assessment of the distribution of character accentuations in patients with different dermatoses can provide insight into how a certain level of adequacy of psychological adaptive response is associated with organic pathological process or genetically existing expression of certain traits. The aim of the study was to found the features of indicators of expression and features of accentuated personality traits in men with psoriasis without taking into account somatotype and in representatives of meso- and endo-mesomorphic somatotypes. Men aged 22 to 35 years, patients with psoriasis (n=100, including 32 with mild and 68 with severe course) at the Department of Skin and Venereal Diseases with a course of postgraduate education National Pirogov Memorial Medical University, Vinnytsya and Military Medical Clinical Center of the Central Region, conducted an anthropometric survey by V. V. Bunak Estimation of the expression and features of accentuated personality traits made according to G. Shmishek The reliability of the difference between the values between the independent quantitative values was determined using the U-Mann-Whitney test. In healthy subjects, taking into account and without taking into account the somatotype, it is seen that the type of physique did not significantly affect the severity of individual traits and their combinations in this group of people. With the increase in the course of psoriasis among subjects without somatotype, there is a decrease in the percentage of persons with hyperthymic and demonstrative and an increase – with emotional, pedantic, anxious, cyclothymic, excitable, dysthymic and exalted type of character accentuation; among patients of mesomorphic somatotype there is a decrease in the percentage of people with stuck and demonstrative and an increase – with emotional, pedantic, anxious, cyclothymic, excitable, dysthymic and exalted type of character accentuation; among patients of endo-mesomorphic somatotype there is a decrease in the percentage of people with hypertension and an increase – with stuck, demonstrative and excitable type of character accentuation. All this maintains a pathologically high level of affective tension, which disrupts the autonomic balance in the body, can be a pathogenic factor in the development of psychosomatic illness and leads to ineffective treatment of psoriasis.


Roadside accidents happen when a vehicle runs off the road. The majority of these accidents are very severe because leaving the road is usually followed by hitting a solid obstacle (tree, pole, support, culvert front wall, barrier). Roadsides are some of the most important issues of road safety. They have been studied for years to identify roadside hazards and the effectiveness of road safety measures such as restraint systems. While restraint systems prevent crashes into obstacles or running off the road down steep slopes, they are obstacles themselves. If wrongly designed and located, restraints may pose a serious risk to the safety of road users. Examples of safety barrier models were analysed to understand how barriers change safety. It was found that the models differ and use different methodologies and data. In building a new analytical tool, the models' differentiating factors were combined to create a comprehensive model to match the Polish conditions.
Fieldwork focussed on sections outside built-up areas, i.e. on national roads of the total length of app. 3,000 km. The data were inventoried separately for the left and right edge of the road and for the central reservation. Potential roadside hazards were identified (e.g. trees, slopes, utility poles, engineering structures) as well as the type of cross-section and existing types of safety barriers (concrete, steel, wire rope). Using the data collected, models of road safety measures were developed. By combining the effect of the roadside and safety measures, the models will help to build tools for road network management at the operational level (concrete locations on the road network) and select the right types of restraint systems and design the clearance zone.


The invention discloses a kind of separation method of scheme for lacosamide analog.The invention provides a kind of separation method of scheme for lacosamide analog shown in formula I, it comprises the following steps:A the reaction mother liquor of scheme for lacosamide analog is carried out washing by (), pickling is washed again;B () concentrating under reduced pressure is evaporated off organic solvent, obtain grease;C described grease is carried out normal phase column chromatography or high performance liquid preparative chromatography by (), obtain compound of formula I;The preparation method of the described reaction mother liquor of scheme for lacosamide analog, comprises the steps:In the two-phase solvent of organic solvent and water, in the presence of alkali and phase transfer catalyst, Formula II compound and methylating reagent are carried out substitution reaction,.The scheme for lacosamide analog shown in formula I of the present invention is the necessary that scheme for lacosamide is carried out with quality control;The separation method of the present invention can be efficiently separating and obtain above-mentioned analog.


As a particular garden in which the principal activity is to exhibit animals,the city zoo should play its dominant with animals instead of the monotonous landscape.If animals and plants are combined together organically and perfectly in a limited space,the city zoo will have a good ecosystem environment to flack the knowledge of plants and animals to people.


Mechanism of interaction between bovine serum albumin(BSA) and isoprenaline hydrochloride (IH) was studied by fluorospectrometry and capillary zone electrophoresis.As shown by the results of fluorospectrometry,significant quenching of fluorescence of BSA was found by its reaction with IH,and as judging from the fluorescene quenching constants(K_q = 2.53×10~(13) L·mol~(-1)·s~(-1) ) obtained by Stern-Volmer equation, fluorescence quenching of BSA by IH was attributed to static quenching.The binding constant and number of binding site were found to be 1.72×10~4 L·mol~(-1) and 1 by applying the equation of site-binding mode respectively. It was shown by the results of capillary zone electrophoresis that:values of binding constant and number of binding site were found to be 4.07×10~4' L·mol~(-1) and 1 respectively.


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Hydrochlorothiazide was investigated for anti-inflammatory action on the exudative and proliferative phases of inflammation The drug exhibited significant anti-inflammatory activity which was not affected by adrenalectomy. Gastric acidity was significantly reduced and there was no evidence of ulceration.


The space curves are highly descriptive features for 3-D objects. Invariant representations for space curves are discussed. The authors introduce a complex waveform representation for space curves. The waveform is parameterized by arc length. Also proposed is an invariant representation of space curves using the 3-D moment invariants of their breakpoints. Space-curve matching using invariant global features is discussed. An algorithm for matching partially occluded 3-D curves is also presented in which an association graph is constructed from local matchings. The mixture cliques of the graph will determine the longest portion of the model curves in the scene.<<ETX>>


Image segmentation is a process of segmenting an image into non-intersecting regions containing homogeneous pixels that are inhomogeneous with those in other adjacent regions. In this paper, a possibilistic clustering algorithm incorporating grey-level histogram and spatial information (PCA_HS) for image segmentation is proposed. The grey-level histogram speeds up the algorithm and the spatial information enhances its robustness to noise and outliers. To assess the proposed algorithm, four widely used validity indexes are computed and discussed. As the experimental quantitative and qualitative results on real images with and without noise show, PCA_HS can preserve the homogeneity and integrality of the regions and hence is more effective and efficient than traditional PCA.


The writer has taken land occupation within the Yuanshi section as an example, summed up the experience from the land use of Beijing-Shenzhen Freeway, and raised the initial countermeasures for land occupation in the project of the south to north water transfer.


The road to the political benefits of the Internet is lined with believers and critics. The believers—who are, depending on the source, either labeled e-optimists or cyber-utopians —hail this new medium of communication as offering not merely new ways of obtaining information, but as revolutionizing the character of democratic society by transcending limitations of time, space, and access and interactive and deliberative citizenship, not hindered by the elite character of traditional mass media. The enthusiasm is often accompanied by the anticipation of a major increase in public engagement in political communication. "The extraordinary opportunities provided by the Internet" can be used as "an instrument of citizenship . . . in which people continually enlarge their horizons, often testing their own views by learning about alternatives" (Sunstein, 2001, p. 194). The inherently nonhierarchical character of the Internet would enable bottom-up initiatives from individuals and groups that are traditionally not interested in or often ignored by politics and politicians. The Internet would make a thousand flowers bloom: Instant and ubiquitous access to government information, political proposals, and policy options would enable citizens to discuss their ins and outs, form opinions, and make fully informed choices that can be instantly and authoritatively communicated to legislators. The idea of "e-democracy," with its implicit assumption of responsive decision making, has its e-pessimists or cyber-realists as well, as the Internet unleashes dreams as well as nightmares. They question the potential powers ascribed to the Internet in mobilizing the politically uninterested. At the same time, they point to the fact that most government sponsored initiatives are not aimed at citizen feedback, and those that are show a "tendency to seek aggregate 'consumer/citizen' views (via e.g. electronic opinion polling, referenda, etc.) on predetermined issues rather than to encourage discourse and deliberation amongst citizens and allow an input to agenda setting" (Hague & Loader, 1999, p. 13). On a global scale, the pessimists remind us that access is often only in the eyes of the beholder: The digital dream may well create new cleavages, between those who do and those who do not have access to and command of such communication resources. Central in most contributions to the debate is the concept of the "public sphere," a realm of our social life—separate from political, religious, or economic interests—where


ABSTRACT Women's professional sport has grown over the last decade and so has academic scholarship investigating it. It is timely to review and consolidate extant scholarship to identify patterns and gaps in research and future directions for research to support continued advancement in women's professional sport knowledge and practice. This paper presents a systematic quantitative literature review (SQLR) of 57 academic peer-reviewed journal articles researching women's professional sport leagues and published between 2000 and 2019. We provide bibliographic findings, extend the typical SQLR approach and provide an inductive thematic analysis of article findings to synthesise the knowledge base present in the extant research. Based on our SQLR findings, we highlight four key research directions, including the need for (1) diversity in inquiry and reflexivity by researchers, (2) innovative and enabling theories and conceptual frameworks, (3) transdisciplinary research approaches and (4) sustainable business models for women's professional sport. We emphasise that to advance our theoretical understandings and sport management practices in women's professional sport, academics must commit to exploring women's sport in new and different ways, to achieve new and different knowledge and outcomes. HIGHLIGHTS Research into women's professional sport leagues is predominantly informed by academics and research contexts from the USA and Australia, and some European countries. Mainstream theories from sports sociology, marketing and management dominate the body of knowledge and most adopt qualitative methods. There appears to be an expectation that women's professional sport should be an exemplar of diversity, inclusion and social change. Opportunities exist, moving forward, for transdisciplinary research to advance women's professional sport knowledge and practice.


The scientific conference has, on at least one occasion, been likened to a rock concert. This was when the new "high-temperature" superconductors were first presented in 1987. There was a packed theatre, where people arrived early to secure a place – many more were unable to – and, whatever the quality of the performance, the audience was always going to be appreciative.


ObjectiveTo investigate the interrelationship between the apoptosis of L78 cell-line of the lung squamous cell carcinoma and it's expression of Rb, Cyclin D 1 gene proteins induced by 9-cis-retinoic acid and to evaluate it's mechanism.MethodsL78 cell-line of the lung squamous cell carcinoma was incubated in vitro and radomly divided into two groups. Experiment group: 5μmol/L 9-cis-retinoic acid( 9-cis RA) was added; control group:0.1% Dimethylsulfoxid was added as a control. After 48 hours incubation, the Rb gene protein expression of L78 cell-line was estimated by immunohistochemistry method; the Rb, the Cyclin D 1 gene proteins and the cell apoptosis were estimated by flow cytometry, and the correlation among them was studied.ResultsThe expression of Rb gene was enhanced,the Cyclin D 1 decreased prominently, and the cancer cell apoptosis increased in experiment group than those of control group (P0.01). There was positive correlation between the expression of Rb gene and the rate of cancer cell apoptosis (r=0.854, P0.05), negative correlation between the expression of Cyclin D 1 gene and the rate of cancer cell apoptosis(r=-0.812, P0.05). ConclusionsThe growth of cancer cells is arrested at G 0/G 1 stage by the way that 9-cis RA can increase the expression of Rb gene and decrease the Cyclin D 1 and simultaneously induce the apoptosis of L78 cell-line of the lung cancer.


Rainfall, earthquakes and human activities are the most relevant factors, which cause triggering of large landslides in mountain regions. Two severe landslides occurred in November 2000 in Slovenia. They attracted the attention of the entire country and also opened some new technical questions. Both landslides were initiated by a period of heavy rainfall. The Stože landslide occurred between 15 and 17 November, 2000 close to Mt. Mangart in the Julian Alps of western Slovenia. It destroyed about 25 ha of forest as well as a considerable section of the road leading over the Predel Pass. The landslide turned to a debris flow and reached the village of Log pod Mangartom more than 4 km downstream, where it took seven lives. Approximately 1 million m of material was displaced. The Slano blato landslide appeared between 18 and 19 November, 2000 near Ajdovščina. Its area was estimated to 20 ha, mostly forest and meadow. Sliding masses were composed from clayey gravel and weathered flysch cover. It was classified as an earth flow. The landslide has not reached the village downstream yet, but it threats it. The paper describes both landslides and their particularities. Special laboratory equipment, large scale shearbox, has been constructed to test the landslide material. From the test results it was observed the landslides were of different type and behavior. Results from both landslide materials were quite different, especially in the shear properties. Key-Words: landslides, debris flow, shear-box, shear strength


instructional process ensures that educators integrate various modes of representation into mathematics instruction for teaching important concepts. Regardless of the mode of representation that the teacher selects for a particular lesson (manipulative models, pictures, or tallies), he or she also displays written number symbols to ensure that students make a connection between the conceptual and abstract representations. For example, if a teacher is using Unifix cubes to demonstrate the concept of subtraction, students should see the numerical representation of the problem (e.g., 8 – 3 =___ ), as well as the cubes. To ensure that students pay attention to the numerical representations in addition to the manipulative or pictorial models, students should read the problem aloud before and after they build the concrete or pictorial model to represent and solve the problem. Guideline 2: Consider Appropriate Structures for Teaching Specific Concepts One of the most important aspects of planning and implementing instruction intended to teach mathematical concepts is determining the appropriate lesson structures to use with a specific concept. The lesson structure is the framework, or the way that the teacher will demonstrate the concept and the way that the students will practice it to increase their conceptual understanding. Although educators agree that using manipulative devices, pictures, and diagrams to represent mathematical concepts is beneficial (Miller, Butler, & Lee, 1998), teachers must also consider the best way to use these materials. Different concepts seem to lend themselves to particular conceptual lesson structures. Included among these structures are comparing and contrasting, examples and nonexamples, and stepby-step processes (Hudson & Miller, 2006). The Compare-and-Contrast Lesson Structure The compare-and-contrast lesson structure is helpful when students need to recognize similarities and differences while they learn the target concept. This lesson structure is particularly useful when teaching geometry, numbers and operations, and measurement standards (Kamii & Clark, 1997; NCTM, 2000). For example, a teacher who is explaining the concept of weight can demonstrate by holding one object in each hand and comparing the weight of the two objects (e.g., "Hmm, which is heavier?"). The teacher can let students handle the objects, which should have distinctly different weights. After the demonstration, students can work in pairs to weigh the objects, compare them, and identify the heaviest object in a set of objects. The compare-and-contrast lesson structure is also useful when teaching such fraction concepts as equivalent fractions (NCTM, 2000). Fraction bars and plastic fraction pies, as well as number lines, are concrete and pictorial materials that allow students to compare fractions and identify equivalent fractions. At the concrete level, students can stack fraction foam pieces to observe the representation of equivalence, such as 4/8 = 2/4 = 1/2, as shown in Figure 4. The teacher can also use a fraction number line to show equivalence. The Example-and-Nonexample Lesson Structure The example-and-nonexample lesson structure is another way to teach a concept. The teacher provides multiple examples of the concept, along with nonexamples that allow the student to discriminate and identify representations of the concept (NCTM, 2000). For example, if the instruction focuses on the concept of a polygon, the teacher begins by showing many examples of polygons of different sizes and shapes, as well as examples of polygons in different positions. The teacher points out the characteristics of a polygon and then elicits these characteristics from the students. When students are consistently able to identify the concept's 30 ■ COUNCIL FOR EXCEPTIONAL CHILDREN 3 ❒ ❒ ❒ +2 ❒ ❒ ❒ ❒ ❒ ❒ 2 ❒ ❒ ❒ ❒ 4 4 ❒ ❒ ❒ ❒ –2


Author(s): Taylor, Nicole; Tamir, Orit | Abstract: The articles in this special collection were presented at the Society for Applied Anthropology meeting in 2018 on a panel affiliated with the organization's Issues in Higher Education Topical Interest Group. This topical interest group focuses on examining how ongoing shifts in student demographics, financial challenges, and national policy impact decision-making and practice at all levels of the institution in complex ways. The articles in this collection explore educational experiences and needs of college students from their perspectives within the broader context of a rapidly changing higher education landscape and with a focus on applying this knowledge to teaching practices in the anthropology classroom. The authors present ethnographic research on students' experiences, discuss implications of findings for the anthropology classroom, and provide concrete strategies that instructors can implement to address students' needs. In doing so, they bring together two fields of study that often appear in the literature as separate areas of focus – the anthropology of higher education and the teaching of anthropology.


The aim of this project is to design and analyze the propulsion system for a tugboat for optimum performance. In so doing, certain approved procedures were followed; these procedures included getting the desired tugboat dimension, using ITTC methods, Gertlers charts, Bp charts etc. to estimate the bare hull resistance of the tugboat, estimating the effective power that must be employed to overcome this tug resistance. Numerical software code was developed to determine the various performance indicators of the propulsion system. The effective power was used as a basis for selecting the main engine and designing of a suitable propeller capable of propelling the tugboat for the various sea state were evaluated. Propeller cavitation was also put into consideration during this design. Hence in matching the engine to the propeller a series of calculations were done across a speed range of 300 - 500 rpm in other to effectively ascertain the engine-propeller matching point. The result shows that the point of engine-propeller matching is at 335 rpm and 2550 KW respectively. This provides a guide for the selection of a main engine with an acceptable sea service margins. All designs were done in accordance to classification organization and regulations.


Experimentally tested RC columns demonstrate that, for large inelastic demands under cyclic loading, damage concentrates within a finite member length around the section of maximum moment. This region length is shown to increase significantly with compressive axial load. The present work addresses the need to incorporate such finding in inelastic analyses of frame buildings and bridges, in order to reconcile the simulation of local (moment-curvature) and global (drift-lateral load) responses. The proposed model combines: (i) a recently developed adaptive force-based beam element, which ensures simultaneously a high degree of accuracy for hardening behaviour and an objective response during the post-peak phase(s); (ii) a new method to estimate the damaged region length, based on the distribution of the steel strains along the compressed longitudinal reinforcement. Numerical tests and comparison with experimental results under distinct values of axial load ratio show an overall satisfactory performance of the model.


In recent years the need and possibilities of implementing the inclusive model of education which implies provision of equal rights and opportunities for education for all students (regardless personal differences) and a more flexible approach to satisfying specific educational and wider social needs of all children has attracted increasing attention in our country. School pedagogues play an important role in promoting and developing the inclusive approach to education. By the research we conducted we wanted to determine the views of students of education on the role of the school pedagogue in the application of inclusive education. Regarding the research technique, we opted for polling, i.e. we construed a questionnaire with both open and closed questions. The research comprised 87 third and fourth year students of education in the Faculty of Philosophy in Belgrade. The results indicate that the examined students do understand the gravity of the problem of students-with-special-needs education. Most of them think that they are not receiving adequate training for work with students with special needs and they singled out the types of knowledge and skills they think would be required in this respect. The paper offers some suggestions for altering the programme documents which define the work of school pedagogues, as well as for curricular changes in Education studies in order to provide better conditions for efficient work of school pedagogues in inclusive education.


This paper derives the theoretical average detection probability of the Fusion Center (FC) with linear minimum mean square error (MMSE) combiner. We consider a centralized cooperative multiple-input multiple-output (MIMO) antenna based reporting network. We assume the sensing channel as an additive white Gaussian noise (AWGN) and the reporting channel as an independent and identically distributed (IID) Rayleigh fading channel. To obtain the average detection probability of FC, average the statistical distribution of output signal-to-interference-plus-noise ratio (SINR) of MMSE combiner and the detection probability of FC over AWGN channel which is a generalized Marcum Q-function. We arrive at a closed form expression of average detection probability by making some approximations in the output SINR distribution where it involves hypergeometric function with two matrix arguments which in turn expressed as an infinite series of zonal polynomials.


We propose and evaluate by simulation a novel membrane electro-absorption modulator heterogeneously integrated on silicon. The device is based on the electron-concentration-dependent absorption of highly doped n-InGaAs. It is predicted that the modulator can be operated over a wavelength range of more than 100 nm and provides a static extinction ratio of 7.2 dB, an insertion loss of 4.4 dB, a modulation speed above 50 Gb/s, and a power consumption of 53 fJ/b. The modulator has a small footprint of 0.4 <inline-formula><tex-math notation="LaTeX">$\times$</tex-math> </inline-formula> 80 um2 (excluding contact pads) and operates on a CMOS compatible 1.5 V voltage swing.


Taking their cue from Plato's deflation of the philosophy of the historical Protagoras, modern interpreters of the Protagoras have tended to discount the significance that the Protagorian myth of the birth of culture has for understanding the discussion between Socrates and the sophist. In this paper I shall attempt to reconstruct Protagoras's approach and to confront it with that of Plato, particularly in respecto of Plato's theory of measurement. I shall contend that Plato's theory and the Protagoras's myth adress the same issue—namely, that of the relationship between good, utility and pleasure. Such a confrontation may help us better to understand the philosophical points of departure that are implicit in the thinking of both the historical Protagoras and the Socratic Plato. It is my thesis that in this confrontation each thinker is offering an alternative approach to the understanding of human nature. Plato proposes that human nature be grasped as the consequence of what the subject knows and does not know, whereas Protagoras deduces knowledge from the very structure of human nature. In the first case human nature is deduced from knowledge; in the second knowledge is deduced from human nature. Two principal issues have to be considered in elucidating the difference between Plato and Protagoras's attitudes. The first concerns the question of whether virtue is teachable. The second has to do with the unity of virtues. Both issues are connected with Plato's well-known assertion that virtue ([aqet≠g) is knowledge ([epist≠glg). Plato and Protagoras adopt different attitudes. Plato considers that virtue is teachable because it is knowledge; that is to say, there is a knowable content that is virtue. 2 The logical upshot of Protagoras's thinking is that virtue is different from knowledge (Prot. 361b 4). However this does not imply for him that virtue is unteachable. Thus, according to Plato, education is possible only if there exists a knowable content and a unity of virtues achieved by means of knowledge; whereas for Protagoras, political education can be pursued even though virtue is not knowledge and there is no unity among virtues. Socrates begins his discussion with Protagoras by raising two objections to the sophist's claim of being able to teach political virtue. Firstly, if virtue were teachable, then the task of teaching it would have to be reserved for experts. But this is intolerable for Athenians, who allow everyone to express his opinion in political matters. (Cf. Prot. 319 …