The paper considers Wasserstein metric between the empirical probability measure of n discrete random variables and a continuous uniform one on the d-dimensional ball and give the asymptotic estimation of their expectation as n → ∞ . Further We considers the above problem on a mixed process, i.e., n discrete random variables are produced by the Poisson process.


The system includes a plurality of nozzles formed in the bottom surface of the print head, including print head. Nozzle is configured to release the liquid onto the substrate. The system is configured to provide a flow of gas through the gap between the bottom surface and the substrate of the print head, including a gas flow module. Gas flow module is configured to inject gas into the gap, it may include one or nozzle above it. Gas flow module may be configured to suction to be applied to the gap.


Background
 Chronic myelomonocytic leukemia (CMML) is a highly heterogeneous myeloid neoplasm with poor prognosis and limited therapeutic options. Tefinostat (CHR-2845) is a cell permeant ester that is converted to an active acid histone deacetylase (HDAC) inhibitor (CHR-2847) by human carboxylesterase 1 (hCE-1), an enzyme predominantly found in cells of monocyte lineage. Pre-clinical studies confirmed selective activity of tefinostat, correlating with hCE-1 expression and acetylation induction, in monocyte derived cell lines, primary CMML and AML (M4/M5) cells (1). A phase 1 study in refractory haematological malignancies showed tefinostat to be well tolerated, with complete remission reported in 1/2 CMML patients (2). Given the compelling rationale for selective activity in monocytoid malignancies, we conducted a phase 2 study to assess safety and efficacy of tefinostat in CMML.
 Methods
 MONOCLE was a single arm phase 2 trial conducted to a Bryant and Day 2-stage design with dual primary endpoints of safety and clinical efficacy. CMML-2 patients were included; additionally CMML-1 patients with symptomatic bone marrow failure or proliferative disease, symptomatic splenomegaly, extramedullary involvement, systemic symptoms or CMML-specific Prognostic Score (CPSS) int-2/high. Tefinostat was administered orally in continuous 28-day cycles starting at 360mg once daily, increasing to 480mg after 4 weeks if well tolerated. Concomitant hydroxycarbamide was permitted only with cycles 1-3. Clinical response was assessed according to International Consortium MDS/MPN Response Criteria (3); responding patients at cycle 6 were permitted to continue therapy. Toxicity was assessed according to CTCAE v4.0.
 Results
 In stage 1, 21 patients were enrolled at 9 centers (Jan-Sep 2017). 20 patients received tefinostat (median age 75 years [64-88], M/F 14/6) including 16 with CMML-1 (80%) and 4 CMML-2 (20%), 8 (40%) with myelodysplastic and 12 (60%) myeloproliferative CMML; respective proportions in CPSS low/int-1/int-2/high risk groups were 5/50/40/5%. Myeloid NGS analysis confirmed a molecularly relatively high risk population: 70% ASXL1 mutation frequency and median 4 (2-7) mutations per patient; other most commonly observed mutations being TET2 (65%), SRSF2 (50%), EZH2 (35%) and NRAS (35%). Prior therapy included azacitidine (3 patients) and hydroxycarbamide (7). 17/20 patients had high hCE-1 levels, assessed flow cytometrically at trial entry in monocytoid cells (vs bulk myeloid population). Median number of cycles of tefinostat received was 4 (1-15). Of 13 patients completing ≥3 cycles of tefinostat, 1 patient achieved clinical benefit (partial bone marrow response at cycle 6 with red cell transfusion independence sustained over 15 cycles of treatment), 9 had stable disease (of whom 1 had transient clinical benefit [MPN-SAF symptom reduction] which was not sustained to cycle 6) and 3 had progressive disease. Most frequent non-hematologic adverse events of any grade were raised creatinine (55% patients), fatigue (40%) and nausea/vomiting (30%). Grade ≥3 AEs judged potentially related to tefinostat included thrombocytopenia (3 patients), fatigue (2), raised creatinine (2), anorexia, AV block, nausea and neutropenia (1 each). Creatinine rises were in all cases reversible following tefinostat dose reduction/cessation. Induction of intracellular lysine acetylation in monocytes (a marker of HDAC inhibition) was observed in 50% of patients (including clinical responders), peaking between days 15-28 of cycle 1. While no clear relationship between baseline hCE-1 expression and clinical response was evident, reductions in marrow monocyte and myeloid blast fractions were seen in both clinical responders.
 Conclusion
 Following failure to achieve a pre-defined minimum number of clinical responses to tefinostat, patient recruitment was not continued into stage 2 of this phase 2 study. Drug tolerability was encouraging although observed renal effects will likely preclude dose escalation in this challenging, often frail patient group. Despite compelling scientific rationale and pre-clinical data favoring this monocyte targeted treatment approach we were unable to demonstrate a clinically significant single agent disease modifying effect in CMML.
 (1) Zabkiewicz J. Oncotarget 2016; 7: 16650-62
 (2) Ossenkoppele G. Br J Haem 2013; 162: 191-201
 (3) Savona M. Blood 2015; 125: 1857-65

 Knapper: Novartis: Honoraria, Membership on an entity's Board of Directors or advisory committees; Celgene: Other: Meeting and travel support; Jazz: Other: Meeting and travel support; Daiichi Sankyo: Other: Meeting and travel support; Chroma Therapeutics: Research Funding. Hills:Daiichi Sankyo: Consultancy, Honoraria. Dillon:Teva Pharmaceuticals UK: Consultancy, Honoraria; AbbVie UK: Consultancy, Honoraria. Pocock:Kent & Canterbury Hospital: Employment. Culligan:Pfizer: Honoraria; Takeda: Honoraria, Other: Support to attend conferences; JAZZ: Honoraria; Merck Sharp & Dohme (MSD): Honoraria; Abbvie: Other: Support to attend conferences; Celgene: Other: Support to attend conferences; Daiichi-Sankyo: Other: Support to attend conferences.


Seasonal variations of renal colic have been described by many authors throughout the world for different countries. No such evaluation has yet been made for Germany. We have collected data to analyse whether such seasonal variations of renal colic are relevant in Germany as well.Prospectively, we have studied n=1049 calcium oxalate stone formers with symptoms of renal colic treated in our department. We have divided them into four groups according to the quarters of the year. For stone analysis, x-ray diffraction / polarizing microscopy was used. Furthermore, the following general parameters have been examined in all patients: age, BMI, blood pressure, stone frequency, diabetes mellitus; blood: creatinine, glucose, uric acid, calcium, sodium and potassium; urine: pH, volume, calcium, uric acid, citrate, ammonia and urea. Using the statistic programme Prism 5 (GraphPad), significant differences between the four groups were calculated by the Kruskal-Wallis-test.In Germany no seasonal variations of renal colic in calcium oxalate stone formers have been found. We have also not found seasonal variations in metabolic parameters or urine composition. Low temperature fluctuations could be a potential explanation. However, there are countries with similar climate conditions showing seasonal variations of acute stone episodes. Another possible explanation for the missing variation in colic is the constant urine composition throughout the year. This was shown for other regions with a constant frequency of acute stone episodes. Further investigations are required to support this hypothesis.


4 workers had dermatitis of the face, and cases 1-4 and 6 were employed in jobs involving charging 4,7-dichloroquinoline to a hot reaction vessel. This operation was performed manually by shovelling from a fibreboard drum. Dermatitis was not seen amongst other workers handling this substance. Further investigations indicated that this material could sublime at high temperatures, and it is possible that this property played a part in the production of the facial dermatitis. Inevitably small quantities of the material would fall upon the outside of the hot vessel and sublime. This could result in sufficient dichloroquinoline in the atmosphere to produce facial dermatitis. 4,7-dichloroquinoline is encountered as an organic intermediate in the manufacture of chloroquine and other quinoline derivatives.


Ballying in school happened not without of couse, but happened because accumulation from problemss in process of educations which have taking place. We cannot adjudg to one of aspect as source cause . One of alternative of which can be gone through for anticipating the happening of ballying in school is with looking for source of root of problem, that is revising function and role of education in family, school, and public. Third this component have to be powered in an optimal fashion, especially area of family, where role of parents in giving" affection" or education of social-emotional which recently don't touch student. Any form of behavior of student in this time is result from education process which have taking place in this country, where parents, teacher and public held responsible. Keywords : education of social-emotional, family, school, public


reactive chemical properties.1 It has bactericidal, sporicidal and fungicidal properties, and is used as a cold sterilizing agent especially for medical, surgical and dental equipment. Its vapors are irritant to skin, eye, nose and lungs. As far as we know there have been no reports that it can cause pneumonia. Here we report a child with chemical pneumonia as a result from glutaraldehyde who presented with acute respiratory failure and was successfully treated with noninvasive mechanical ventilation via a nasal mask.


To improve the dynamic performances of Permanent Magnet Synchronous Motor (PMSM) drive, a novel implementation of speed controller based on adaptive fuzzy logic is presented in this project. Using the output of the fuzzy speed controller (FC), the quadrature axis current reference value can be obtained.
The basic principle of vector control is to decouple the stator current to get direct axis and quadrature axis components. The vector control strategy is formulated in the synchronously rotating reference frame. The steady-state response of the predictive control can be effectively improved by using a simple time delay control approach. To increase the performances of PMSM drive, an adaptive speed controller based on fuzzy logic is proposed. The availability of the PMSM parameters is confirmed by computer simulations. The results of simulation have shown that the PMSM drive with the proposed control scheme has the merits of simple structure, robustness, quick tracking performance.
In this project, the conventional PI speed controller has been replaced by the fuzzy controller. It combines the capability of fuzzy reasoning in handling uncertain information and the ability to compensate of the disturbance voltage observer on-line. The proposed control scheme has been testified by simulation, the results indicate the PMSM drive with the adaptive fuzzy controller will have the ability of quick recovery of the speed from any disturbances and parameters variation. Accordingly, the proposed PMSM drive will have better dynamic performances and robustness.


Epidemiological data regarding antipsychotic initiation in elderly patients with stroke are limited. We aimed to investigate the incidence, prescription patterns and determinants of antipsychotic initiation in elderly patients with stroke.


OBJECTIVE
Previous studies have demonstrated that the lower renal excretion of urates in patients with hyperuricaemia is inversely related to plasma very low-density lipoprotein (VLDL) levels, and the different genotypes of the apolipoprotein E gene are related to the plasma levels of lipids. The aim of this study was to determine the prevalence of apolipoprotein E in hyperuricaemic patients and to investigate whether the renal excretion of urates is conditioned by the apoliprotein E genotype.

METHOD
The plasma levels of lipoproteins, cholesterol, triglycerides and uric acid, and the renal excretion of uric acid were studied in 68 patients with gout and in another control group of 50 healthy subjects. Both groups were genotyped for apolipoprotein E by means of an amplification technique and inverse hybridization.

RESULTS
The prevalence of the E2 allele was greater in the patients than in the control group. The levels of cholesterol, triglycerides and uric acid were greater in the patients, whereas the levels of high-density lipoprotein were lower. The patients with the E2 allele had higher levels of triglycerides in VLDL and intermediate-density lipoproteins and a lower renal excretion of urates.

CONCLUSIONS
These results show that the reduced renal excretion of uric acid in patients with gout is mediated by high levels of VLDL and by the high prevalence of the E2 allele of apolipoprotein E.


The method of power network partition evaluation and N-1 checking on important lines or equipments is adopted to explore the risk evaluation and countermeasures of Guangzhou power network at shortage of high-voltage direct-current(HVDC) power capacity.According to the rules of power balance and control during power shortage,and combined with the load prediction of power network areas,the scheme of power dispatching and balancing is made from the central,northern and southern power network of Guangzhou,local power plants and area load control.N-1 checking is made on some important lines and equipments,including Tianguang HVDC blocking,main transformer of Beijiao Substation,Huangpu Power Plant B,Guangrui Line,Zengtang Line;corresponding countermeasures are formulated.The practical operation of power network shows the combination of partition evaluation and N-1 checking on important equipments is effective to prevent power network risk.


The recently released Bluetooth 5.1 specification introduces fine-grained positioning capabilities in this wireless technology, which is deemed essential to context-/location-based Internet of Things (IoT) applications. In this paper, we evaluate experimentally, for the first time, the accuracy of a positioning system based on the Angle of Arrival (AoA) mechanism adopted by the Bluetooth standard. We first scrutinize the fidelity of angular detection and then assess the feasibility of using angle information from multiple fixed receivers to determine the position of a device. Our results reveal that angular detection is limited to a restricted range. On the other hand, even in a simple deployment with only two antennas per receiver, the AoA-based positioning technique can achieve sub-meter accuracy; yet attaining localization within a few centimeters remains a difficult endeavor. We then demonstrate that a malicious device may be able to easily alter the truthfulness of the measured AoA, by tampering with the packet structure. To counter this protocol weakness, we propose simple remedies that are missing in the standard, but which can be adopted with little effort by manufacturers, to secure the Bluetooth 5.1 positioning system.


From an analysis of the design assembly lines method, we concluded that beyond formal data intervene informal data which are important for the choice of solutions and the taking of decisions. It's why we propose a new methodology which breaks with classic approaches and is based on a systemic knowledge approach. The design of assembly lines is reduced to a construction of semantic model by the estalishment of associations bonds between entities emaning from a vocabulary base (which contains trade vocabulary), technologic referentials (which contains validated projects and formal or informal rules) or entities created dynamicaly by an expert.


This abstract presents the authors' recent results on noise-enhanced computation, with specialized application to an error-correction decoding algorithm widely used in digital communication systems. Random defects are an increasingly troublesome problem for densely integrated electronic circuits. In this work we focus specifically on noise-induced transient upsets that can occur in nano-scale switching devices. There has recently been increasing interest in noise-tolerant design, since there is continual pressure to reduce the signal energy in electronic circuits, and eventually it will be necessary to perform computation at a very low signal-to-noise ratio. Some researchers propose sacrificing reliability in order to reduce energy consumption, which is acceptable for some applications that are inherently tolerant to momentary or intermittent faults (audio or image processing, for example). In contrast to noise-tolerant design, some researchers argue for noise enhanced solutions by using algorithms that benefit in some way from random upsets. Noise-enhanced solutions are partly motivated by biological examples, particularly neural signal processing, in which there are several instances where neural function is enabled or improved by some form of noise [3]. In this work, we present a case study showing how one algorithm is transformed into a noise-enhanced form. The transformation is not quite automatic, but nevertheless sheds light on a heuristic procedure that may be applied more broadly. The transformation is based on the stochastic gradient ascent heuristic, which is a well-known method for constrained optimization problems. The challenge is to transform the problem into a form suitable for applying the stochastic gradient ascent heuristic.


A novel very‐high frequency (VHF) band spaceborne phased antenna array for satellite‐automatic identification system/VHF data exchange (SAT‐AIS/VDE) applications operating at 159 MHz is proposed in this letter. Element phase shifting is achieved by controlling each element mechanical rotation angle rather than the phase shifter behind each element. Thanks to the new working scheme, the proposed array shows several advantages over its former counterpart, including low cost, high power capacity, and broad phase‐shifting bandwidth. This letter explains the basic principle, and presents a preliminary study on element rotation angle controlled phased antenna array technology, and an eight‐element‐array which is implemented on solar panel supporting plate is designed to validate the concept.


The "hopping" phenomenon in the phase space of a ship rolling model with two coexisting attractors, representing the heave and heavelroll responses, is investigated. The noise-induced erosion of basins of attraction is studied using the simple cell-to-cell mapping technique. The power spectra of a function, which monitors the hopping phenomenon and determines the phase durations of roll motions, are shown to exhibit 1/f noise, or power-law behaviour. The behaviour is interpreted using a recently proposed general principle based on the extremal dynamics; the related implication is also discussed. PARAMETRICALL Y EXCITED SHIP ROLLING The governing equation for roll, Eq. 1, is coupled with the (3) (2) (1) 1 (b)2 GMo=zf-0.5+ 12 d As described in a previous paper (Liaw, 1994), the coupled heave and roll motions can be represented by the following equations of motion: where the dots denote derivatives with respect to time t; e and Z are respectively the roll and normalized relative heave displacements; (i)r and (i)h ' the linear roll and heave frequencies; ~r and ~h' the linear roll and heave damping ratios; d, band zf represent respectively the draught, beam and water surface elevation. The static metacentric height, GMo' for a ship with a rectangular crosssection is given as: ... {I [1 (b)2 e+2~,(i),e+(i);sine 1+-tane2 2GMo 12 d Following an idea suggested by Rainey and Thompson (1991), the stability behaviour of a ship can be evaluated by studying the evolution of its safe basin (e.g., the basin of the H-attractor). As pointed out by Sanchez and Nayfeh (1990), attractors associated with large roll responses can, in some cases, go through bifurcations and crises and lead to capsizing. The above-mentioned studies were all based on the assumption that the heave excitation is harmonic, or at least periodic. In actual sea environments, the heave excitation will not be periodic; noise is always present. It would therefore be interesting to know how the parametrically excited system is affected by additive noise in the heave excitation. A significant number of research works have been presented in the last decade in the challenging area of noisy nonlinear dynamic systems, e.g., Moss and McClintock, 1989; Pike and Lugiato, 1987; Kapitaniak, 1988. For dynamical systems with multi-attractors, noise-induced hopping phenomena (Arecchi and Califano, 1984) are directly relevant to the problem of parametric resonance. This paper investigates the hopping behaviour in parametrically excited ship rolling when the system has two coexisting attractors, e.g., Hand HR. In recent years, attempts have been made to interpret the qualitative behaviour of ship instability in terms of the safe basin of attraction in the phase space (Thompson, Rainey and Soliman, 1990; Nayfeh and Sanchez, 1990). For the well-known instability phenomenon of large rolling motions of ships in longitudinal waves, the problem has been studied using coupled heave-roll models of parametric excitations (Sanchez and Nayfeh, 1990; Liaw, Bishop and Thompson, 1993). In the case when the natural frequency of a ship in heave is about twice its roll frequency and is close to the wave frequency, large-amplitude roll motions, attributable to "principal parametric resonance," and capsizing can occur even if there is no direct roll excitation. The equations of motion governing the parametric resonance phenomenon described above are usually derived based on an idealized two-dimensional model of the ship. Heave excitations are necessarily simplified in order to keep the numerical efforts of solving the nonlinear dynamic problem to a manageable level. The heave excitations due to regular longitudinal waves are very often represented by harmonic forces. If only the instability conditions for parametric resonance are of interest, the roll angle responses are assumed to be small and the governing equations can then be simplified to either a Mathieu or Hill equation (Liaw, 1994). Analytical solutions for the instability conditions can be readily derived from the Mathieu or Hill equation. However, if one is interested in the large roll responses and not just the conditions for roll responses to occur, nonlinear equations including large-angle effects have to be considered. Numerical analyses of the coupled heave-large roll system have shown that the system can have more than one steady-state response or attractor (Liaw et ai., 1993) near the principal resonance region. Besides the heave-only response (H-attractor), which is the steady-state heave response without roll, there are also the coupled heave and subharmonic roll response of order 2 (HR-attractor). Each attractor has its own basin of attraction, Le., the set of initial conditions which lead to the particular attractor. Within the resonance region, the ship can have large rolling motions, even without direct roll excitation, if its initial conditions are inside the basin of the HR-attractor. INTRODUCTION *ISOPE Member. Received January 20, 1995: revised manuscript received by the editors March 27, 1995. The original version (prior to the final revised manuscript) was presented at the Fifth International Offshore and Polar Engineering Conference (ISOPE-95), The Hague, The Netherlands, June 11-16, 1995.


A general consideration of the three-terminal silicon piezotransducer (TTSP transducer) is described in the paper. The boundary problem is established and solved for the TTSP transducer with classic rectangular form of the current spread region (CSR), the analytical equations for potential distribution are obtained. The linear model of TTSP transducer presented in the paper allows us to describe the TTSP transducer as an external electrical circuit element, to calculate the difference between output currents and voltages on output contacts as a function of strain as well as the sensitivity of the transducer. The geometrical correction function is calculated in this paper for the considered classic rectangular form of the CSR. The sensitivity of the TTSP transducer is compared with the sensitivity of a four-terminal transducer with classic rectangular form. It follows from this comparison, that the four-terminal silicon transducer can be considered as a full analog of the piezoresistive Wheatstone bridge, whereas the TTSP transducer can be considered as an analog of a half-bridge circuit only.


Cryptographic voting protocols have recently seen much interest from practitioners due to their (planned) use in countries such as Estonia, Switzerland, France, and Australia. Practical protocols usually rely on tested designs such as the mixing-and-decryption paradigm. There, multiple servers verifiably shuffle encrypted ballots, which are then decrypted in a distributed manner. While several efficient protocols implementing this paradigm exist from discrete log-type assumptions, the situation is less clear for post-quantum alternatives such as lattices. This is because the design ideas of the discrete log-based voting protocols do not carry over easily to the lattice setting, due to specific problems such as noise growth and approximate relations. This work proposes a new verifiable secret shuffle for BGV ci-phertexts and a compatible verifiable distributed decryption protocol. The shuffle is based on an extension of a shuffle of commitments to known values which is combined with an amortized proof of correct re-randomization. The verifiable distributed decryption protocol uses noise drowning, proving the correctness of decryption steps in zero-knowledge. Both primitives are then used to instantiate the mixing-and-decryption electronic voting paradigm from lattice-based assumptions. We give concrete parameters for our system, estimate the size of each component and provide implementations of all important sub-protocols. Our experiments show that the shuffle and decryption protocol is suitable for use in real-world e-voting schemes.


ABSTRACT We examined the concept of vegetation convergence—similar vegetation in similar, but disjunct, environments—using chaparral as it occurs on five continents (chaparral, fynbos, garrigue, kwongan, maquis, mattoral) as a case study. Research on chaparral in the past two decades has generated sufficient information to make a detailed comparison possible. The degree of convergence was found to be superficial; significant differences exist in physiognomy, leaf and life-form spectra, species richness, morphological adaptations to fire, phenology, biomass, and productivity. In addition, ecologically important differences in such abiotic environmental factors as intensity of summer drought, fire frequency and intensity, and soil nutrient status were apparent. Finally, the traditional linkage of chaparral vegetation with mediterranean-type climate does not consistently exist in North America; chaparral ranges beyond the limits of mediterranean climate areas. We need to reexamine not only our ideas about co...


The objective of the present study was to investigate the relationship between servant leadership and intrapreneurship by the explanation of the role of organizational culture in the private banks (Pasargad, Parsian, Eghtesad-e Novin, Dey) of districts one, two and, three of the city of Tehran. The population of the study includes the entire employees of the banks of Pasargad, Parsian, Eghtesad-e Novin, and Dey located in districts one to three of Tehran, counting as 616 individuals. In terms of objective, the present study is a developmental applied study. Through the application of the Cochran's formula, the research sample size was determined as 425 individuals. The samples have been collected through the application of stratified sampling method and the required research data were collected through the application of the servant leadership, intrapreneurship and, organizational culture inventories. For the purposes of analysis of the yielded information and testing of the hypotheses, the statistical tests of K-S, ANOVA and Pearson's correlation coefficient were made use of. Findings revealed that the culture of the Pasargad Bank is a compatible culture in which there exists a statistically significant relationship between the variables of servant leadership and intrapreneurship (0.82). The culture of the Parsian bank, on the other hand, does not hold any statistically significant relationship between the former and latter variables. Not unlike the Pasargad Bank's, the culture of Eghtesad-e Novin Bank is also a compatible one in which there is a statistically significant relationship between the former and latter variables (0.78). Lastly, it has been found out that similarly to the Parsian bank's, the culture governing the atmosphere of The Dey bank also lacks any statistically significant relationship between the variables under study.


Abstract: This paper investigates the problem of global finite-time stabilization by state feedback for a class of stochastic nonlinear systems with low-order nonlinearities, to which the existing control methods are inapplicable. By skillfully adopting the method of adding a power integrator and constructing twice continuous differential Lyapunov functions, a stepwise constructive continuous state feedback control methodology is proposed. Based on stochastic finite-time stability theorem, it is proved that the solution of the closed-loop system is finite-time stable in probability. Two simulation examples are provided to illustrate the effectiveness of the proposed approach.


The paper compares two different approaches to design an innovative probe with optimized heated area for laser ablation of solid tumors: micro-patterning of the fiber delivery tip, and exploitation of the dissipation of plasmonic waves at the metal-dielectric interface. Both probes integrate a fiber Bragg grating for real- time monitoring of the obtained temperature increase to provide feedback to surgeons in practical applications. Experimental characterizations carried out using liver phantoms and ex-vivo porcine livers have demonstrated that both approaches can be used for the devised application, although further optimizations and tests are still necessary before clinical assessment.


1. Engelbrecht E, Heinert K. Klassifikation und Behandlungsrichtlinien von Knochensubsanzverlusten bei Revisionsoperationen am Huftgelenk mittelfrsige Ergebnisse. Primare und Revisionsalloarthroplastik Hrsg-Endo-Klinik, Hamburg: Springer-Verlag, Berlin; 1987:189. 2. Merle d'Aubigne R, Postel M. Functional results of hip arthroplasty with acrylic prosthesis. J Bone Joint Surg Am 1954;36:451. 3. Hood RW, Wright TM, Burstein AH. Retrieval analysis of total knee prostheses: a method and its application to 48 total condylar prostheses. J Biomed Mat Res 1983;17:829. 4. Carlsson AS, Gentz CF, Stenport J. Fracture of the femoral prosthesis in total hip replacement according to Charnley. Acta Orthop Scand 1977;48:650-5. 5. Chao EYS, Coventry MB. Fracture of the femoral component after total hip replacement. An analysis of fifty-eight cases. J Bone Joint Surg Am 1981;63:1078-94. 6. Charnley J. Fracture of femoral prostheses in total hip replacement. A clinical study. Clin Orthop 1975;111:105. 7. Buttaro M, Mayor M, Van Citters D, Piccaluga F. Fracture of a proximally modular, distally fluted uncemented implant with diaphyseal fixation. J Arthroplasty 2007;22(5):780-3. 8. Bohm P, Bischel O. Femoral revision with the Wagner SL revision stem: evaluation of one hundred and twenty-nine revisions followed for a mean of 4.8 years. J Bone Joint Surg Am 2001;83(7):1023. 9. Woolson ST, Milbauer JP, Bobyn JD, Yue S, Maloney WJ. Fatigue fracture of a forged cobalt-chromium-molybdenum femoral component inserted with cement. A report of ten cases. J Bone Joint Surg Am 1997;79(12):1842.


...................................................................................................................... II CHAPTER 1: INTRODUCTION ................................................................................................. 1 1.1. Background and problem statement ............................................................................... 1 1.1.2. Background .................................................................................................................... 1 1.1.2. Problem statement ........................................................................................................... 4 1.1.3. Preliminary literature study ............................................................................................... 4 1.2. Aim and objectives ........................................................................................................... 6 1.2.1. Aim ....................................................................................................................... 6 1.2.2. Objectives ....................................................................................................................... 6 1.3. Central theoretical argument ........................................................................................... 6 1.4. Research design/Methodology ........................................................................................ 7 1.5. Concept clarifications ...................................................................................................... 7 1.6. Ethical considerations ...................................................................................................... 8 CHAPTER 2: HISTORICAL BACKGROUND ........................................................................... 9 2.


Guide to assist students with the final project of researching 20th century music. Students will explore two dominant and antagonistic approaches to composition: extended tonality and serialism, in addition to texturalism, experimentalism, and minimalism Selections of musical compositions, biographies and more.


Siemens is currently preparing, installing and commissioning three IONTRIS particle therapy accelerator systems – two in Germany, in Marburg and Kiel, and one in Shanghai, China. Siemens IONTRIS is based on a synchrotron to accelerate protons and carbon ions for clinical applications up to 250 MeV resp. 430 MeV/u. The injector part consists of an RFQ to accelerate protons and light ions up to 400 keV/u followed by an IH-cavity, wherein the particles reach an energy of 7 MeV/u. The results of the commissioning of the RFQ at a test facility in Denmark will be presented.


The results of ultrasonic and volumetric measurements were
 used to obtain the excess molar enthalpies for binary liquid mixtures containing
 cyclohexane, as the common component, and primary aliphatic alcohols
 (n-propanol, n-butanol and n-pentanol) at 293.15 K. The
 excess molar enthalpies of those systems are positive in the whole
 concentrations range and show evidently different concentration dependences. The
 excess internal pressure of the liquid mixtures, determined in a few different
 ways, are negative for all the systems. The behaviour of those excesses are
 discussed in terms of intermolecular interactions in the binaries and the
 self-association potential of the alcohols.


Using state-of-the-art techniques in hair transplantation, a natural-appearing result should be the expected outcome. Older techniques of hair transplantation usually did not produce this level of excellence, and poorly performed procedures usually result in an unnatural appearance as well. As a consequence, there are a considerable number of patients who have a cosmetically unsatisfactory, hair-transplant result (Figs 21.1A and B). These unfortunate patients often have unnatural-appearing hair grafts as well as emotional wounds as a result of a previous, adverse experience with their original, or several previous, hair-restoration surgeons. In addition to any technical considerations, managing the patient with cosmetic disfigurement Managing Aesthetic Problems following Hair Transplantation 21


ABSTRACT The paper is a rudimentary attempt to present a nonrepresentational, Affordance-Effectivity-Context (AEC) framework of object perception and use, in children's pretend play. The aim is to invoke AEC as an alternative explanatory framework, in contrast with the dominant symbolic explanation of pretend play.


Digitalization has been the need of the modern era but yet the most important fact lies in the behavioral aspect of the consumer, whether consumer is ready to accept or has acknowledged himself/herself with the digital instrument available in the economy whether in the retail or any other medium of financial transaction. The study identifies that only 2.02% of digital transaction is catered by India in the world Economy. Cashless economy is the need and has become the most vulnerable to the aspect of perception and attitude of the individuals who are still in a way of promoting liquid or cash mode of payment. This provide a major emphasis to the point supported by previous studies as well as market research done on the basis of survey method, that cashless economy is not yet prevalent within our very own nation as consumer behavior and its different components cater the major challenge for the esteemed cause and a serious initiative led by our own prime minister Narendra Modi. The money supply and demand chain have to be circulated in the economy as well as the individuals in such a way that traditional approach of consumer behavior should be transformed to the current demanding and modern digital economy. Thus, the finding of this research paper identifies the challenges of transforming or shifting the mode of payment to digitalization on the note of changes in consumer behavior and its components. This is a research based on primary data obtained by survey method on the basis of questionnaire as the key instrument over a sample size of 101 individuals and analyzed using the digital software Microsoft Excel 2019.


Taking the Liaoning Technical University as an example, this paper studies and analyzes the learning condition of elective tennis course for female students of ordinary universities. The result showed that the teaching effect and learning condition was unoptimistic, student's learning interest tended to decrease. This paper carried out the experimental research in the feasibility of adopting shorts tennis teaching in elementary stage for female students. It concludes that it can help to improve students' learning interest and make the students master tennis technique better by adopting short tennis and transitional ball teaching.


High performance computer technology is the base of the modern scientific and technological researches, engineering development and large-scale data processing. By using high performance computers, we can solve problems that could not be solved by conventional theoretical and experimental methods ,and can also treat enormous data that can not be processed by traditional technology. The parallel computing is an important approach to realize high performance computation. This paper mainly discusses how to make a parallel computation by MPI technique on SGI Origin 2000. With an example, we also introduce how to convert a serial Jaobi's iterative program into a parallel one.


Abstract An approach is presented to formulating the optimization problem of linear discrete-time systems in the presence of both waveform-type and noise-type disturbances. In addition, the plant output measurements are allowed to be corrupted by additive noise. It is shown that the optimal control, which minimizes the specified performance index and ensures that all closed-loop poles lie inside a circular region within a unit circle, can utilize the energy stored in waveform-type disturbance. An illustrative example is provided and simulation results are included to demonstrate the effectiveness of the presented approach.


Summary The literature indicates that dantrolene sodium has produced negligible cardiovascular changes in intact dogs and in patients, but caused depression in the isolated perfused heart. In nine consecutive experiments rat hearts were perfused by means of a modified Langendorff preparation with 3.5% bovine albumin in buffered, mammalian Ringer's solution. Perfusion pressure and temperature were kept constant. Flow was measured with an infrared drop counter. Continuous recordings were made of heart rate, coronary flow, resting length, intraventricular pressure, force displacement and their first derivatives. Statistical analysis of all parameters before and during the perfusion with dantrolene sodium solution showed no significant changes for the same period of time. These results show that dantrolene sodium has no effect and do not confirm recent publications which reported a marked myocardial depression by dantrolene sodium.


Introduction. In a birational transformation between two surfaces to certain curves of one of the surfaces may correspond simple points of the other. Such curves have been called exceptional curves. Exceptional curves have been subdivided into those of the first or second kind according as a point of the curve is not or is transformed into a curve of the other surface. The ones previously considered have either been irreducible or consisted of at most two components. A treatment of reducible exceptional curves with components all simple is found in (4, Chap. II, 6). We shall consider exceptional curves of the first kind with s irreducible components, each counted a certain number of times. This case arises when the birational transformation possesses infinitely near fundamental points on one or several irreducible algebroid branches. In the sequel we shall use some fundamental notions of linear systems of curves on an algebraic surface and the theory of singularities as developed by Enriques (3, pp. 327-399). Sections 1 and 2 of this paper are devoted to definitions and the derivation of the virtual degree and genus of an exceptional curve of the first kind; the presenitation here is parallel to but more complete than that found in (4, Chap. II, 6). In sections 3 and 4 we introduce s fundamental points of the birational transformation, mentioned above, on that surface where the given exceptional curve has been changed into a point, and limit ourselves to the case in which these fundamental points lie on a single irreducible algebroid branch. In 5 we consider the correspondence between the irreducible components of the given curve on the one surface and the immediate neighborhood of each of the fundamental points on the other surface. In 6 we determine the multiplicities of these fundamental points on branches of lowest order passing through the first a (ca,? s) of them. In 7 we describe the intersections of the irreducible components of the given exceptional curve, using extensively the notion of proximate points introduced by Enriques in his theory of singularities (3, p. 381) ; in 8 we study the classification of the s fundamental points as free points or satellites when the intersection numbers


By analyzing the characteristics of problem-based learning and the subject of plant pathology,and their correlation,it was proposed that problem-based learning is useful in the teaching of plant pathology,which would be important for quality education and cultivating the students' ability to solve concrete problems independently.


After tanning the tussah silk,it becomes a certain against germs.In the test,the tussah silk has much more to restrain the germs which infected the many kinds of skin diseases.


The Military Culture of the Adyges occupied a significant place in their lives. In this regard, particular scientific interest has a horse as a part of the Military Culture of the Circassians. It was not only the means of transportation, but also played a huge role in the military and physical training of the younger generation. A horse and a rider were one unit, they showed an example of bravery and courage.


Image feature selection is the significant part in pattern recognition,image understanding and so on.The relief algorithm has a blind deficiency in training feature weight.Q-relief was a new algorithm which was based on dividing instance set in self-adapting.Q-relief was proposed to solve the blind selection problem in the original relief algorithm.The presented algorithm was applied in Trouble of Moving Freight Car Detection System(TFDS).The classification results show that the Q-relief algorithm can improve the accuracy of recognition compared with other algorithms.


Conductive polymer-based hydrogels (CHs) have gained increasing attention as flexible electrode materials for making high-performance flexible supercapacitors (FSCs). However, the amorphous nature ...


The strength of reinforced concrete slab can fail because of over loading. One way to continue without any rebuilding is by doing structural strengthening. This experiment's aim is to know the enhancement of flexural capacity, stiffness, ductility and failure pattern of a bridge slab which is strengthened by using additional reinforcing bar on the tensile zone and epoxy adhesive material. Four reinforced concrete slabs, consisted of two slabs without strengthened (PK), two slabs were strengthened equal to 60% (PPTT 60%) and 120% (PPTT 120%), were made in order to know the difference happened as the result of the increasing of strength given. All specimens had dimensions of 1000 mm x 1800 mm x 100 mm. Specimen was placed on the loading frame with simply supported edge on both ends and was given static load as wide as tire on the middle of the slab span. Numerical approach using ATENA 3D non-linear analysis program was done in order to give comparison to the result of experiment. The result of the flexural capacity of PK, PPTT 60% and PPTT 120% successively are 38.2 kNm, 60.4 kNm, and 67.6 kNm. By comparing them to control slab (PK), flexural capacity of the reinforced concrete slab with additional bar for PPTT 60% and PPTT 120% increase, each of 58.12% and 76.96%. The increase of stiffness of the reinforced concrete slab is 66.996% and 70.689%, each for PPTT60% and PPTT 120%. The ductility factor of PPTT 60% and PPTT 120% decrease, each of 25.124% and 63.859%, compared to control slab. PK slabs experience flexural failure pattern, while flexural strength PPTT 60% slab and PPTT 120% slab experience combination failure pattern between flexure which is more dominant and shear.


Utilizing rubber shreds in civil engineering industry such as geotechnical structures can accelerate generated waste tire recycling process in an economical and environmentally friendly manner. However, understanding the rubber grains strength parameters is required for engineering designs and can be acquired through experimental tests. In this study, small and large direct shear test was implemented to specify shear strength parameters of five rubber grains group which are different in gradation and size. Moreover, artificial neural networks (ANN) are developed based on the test results and optimized networks which best captured the shear stress (τ), and vertical strain (ev) behavior of rubbers, are introduced. Additionally, a prediction model using the combinatorial algorithm in group method of data handling (GMDH) is proposed for the shear strength and vertical strain in the arrangement of closed-form equations. The performance and accuracies of the proposed models were checked using correlation coefficient (R) between the experimental and predicted data and the existing mean square error (MSE) was evaluated. R-values of the modeled τ and ev are equal to 0.9977 and 0.9994 for ANN, and 0.9862 and 0.9942 for GMDH models, respectively. The GMDH proposed models are presented as comparatively simple explicit mathematical equations for further applications.


The set of two partial differential equations for the Appell hypergeometric function in two variables F_4(a,b,c,a+b-c+2-h,x,y) is shown to arise as a null vector decoupling relation in a 2h-dimensional generalisation of the Coulomb gas model. It corresponds to a level two singular vector of an intrinsic Virasoro algebra.


As statistical time series social indicators are used to monitor the social system helping to identify changes and guide interventions to alter the course of social change. Extending time series into the future while an imperfectly developed art enables more realistic planning. The geographic allocation of resources by governments through ecological indicators redistributes funds more equitably. Social indicators lend themselves to geographic disaggregation and analysis by successively smaller area units: nation region state subregion district or county. Cities are similarly into ecological areas. Such detail makes possible comparison of trends of ecological units and opens the analytical possibility of interrelating social with physical and biological indicators. This yields insights into the influences of population social organization technology and environmental effects upon a public problem or concern. By combining with programmatic activities to alter the rate and direction of change social indicators may play a role in social transformations. The social indicator "movement" has led to improvements in social measurement social reporting and social accounting and has stimulated measurement of the quality of life. By employing social indicators sociological research should include the time dimension ecological variables and should attempt forecasts of the furture.


The invention discloses an optical fiber gyroscope with an optical fiber ring adopting a double-ring design. The optical fiber gyroscope comprises a light source, a photoelectric detector, an optical fiber coupling device, a signal processor, an optical modulator and an interference part, wherein the interference part comprises two optical fiber rings and a heat insulation device; the heat insulation device comprises an inner cavity and an outer cavity; a hard insulating ring is mounted between the inner cavity and the outer cavity; a heat guide groove is mounted in the inner cavity; the two optical fiber rings are symmetrically mounted on the two sides of the heat guide groove; a small hole is formed in the heat guide groove; corresponding ends of the two optical fiber rings are spliced and a splicing point is located in the small hole of the heat guide groove; leading-out ends of the two optical fiber rings are led out from other small holes of the heat guide groove and penetrate through the inner cavity and the outer cavity respectively; the leading-out end of one optical fiber ring is connected with a first output end of the optical modulator and the leading-out end of the other optical fiber ring is connected with a second output end of the optical modulator; and the small holes on the heat guide groove are sealed, and the inner cavity and the outer cavity are sealed. The optical fiber gyroscope has the advantages of high temperature stability.


Tropical-like cyclones occasionally develop over the Mediterranean Sea, sometimes attaining hurricane intensity and threating the islands and coastal regions. These small-scale warm-core storms, called medicanes (MEDIterranean hurriCANES), operate on the thermodynamic disequilibrium between the sea and the atmosphere and in this respect, as well in their visual appearance in satellite images, are much like tropical cyclones.


In this paper the technical criteria for choosing the optimal fuel cell for application in stationary field is presented, being developed particularly for application in passive houses domain. In this matter the initial context has been set, respectively the technical characteristics of object to which implementation of a system based upon the fuel cell is wanted, and also the specific characteristics of fuel cells and the decision criteria of the technical solution have been set. In order to choose the right version, two multicriteria methods to rationalise the decision have been applied, after analyzing the existent typologies and establishing the compatible versions with the demands from the stationary domain, and in the end the obtained results have been compared. Key-Words: fuel cell, choosing the optimal technology, Onicescu Method, global evaluation of performance technology, stationary fuel cells, passive house.


Two mucin‐producing cell clones (16.2 and 12.2) and a mucin‐deficient clone (15.2) were selected from the established human adenocarcinoma cell line HT‐29 by limiting dilution and Alcian blue staining. The amounts of the mucin antigen detectable on the cell surface with the monoclonal antibody (MAb) AM‐3 decreased in the order HT‐29 > 16.2 > 12.2 > 15.2 = 0. The binding avidity of AM‐3 antibody to cells as well as to mucin extracts from each cell line decreased in the same order, indicating that the epitope density on the cell‐bound mucins was highest in HT‐29 and lowest in 12.2 cells. The parental line and the mucin‐producing cell clones 16.2 and 12.2 showed no contact inhibition and grew as aggregates, while the 15.2 cells were well spread and formed a regular monolayer. The mucin‐producing cell lines injected into nude mice yielded solid tumors with different growth rates (HT‐29 > 16.2 > 12.2), while the 15.2 cell clone was not tumorigenic at all. The relative amounts of total mucin‐bound hexoses and of the mucin epitope AM‐3 decreased in the xenografts in the order HT‐29 > 16.2 > 12.2. The present system is suitable for investigating the role of mucins in growth of colon carcinoma cells and indicates that increased tumorigenicity in nude mice coincides with the increase in total mucin expression and the expression of the AM‐3 mucin epitope in tumor tissue.


The concept of "High Conservation Value" which was initially used by the Forest Stewardship Council, now plays an increasingly important role in several areas, and most significantly in the design and implementation of development projects. Within the framework of certification of community forests in Cameroon, this concept has been implemented in close collaboration with interested communities. Based on the activities conducted, it is worth noting that the consideration of informal management methods appear to result in better protection of biodiversity. Several categories of High Conservation Values were identified in 2 community-managed forests (Cooperative des Paysans de la Lekie & Bimbia Bonadikombo Community Forests) in Cameroon. Rare or endangered ecosystems, more than 300 plant species and more than 20 wildlife species, including endemic, rare, threatened or endangered species were found. Traditional conservation methods based on culture, as well as some ancestral practices and beliefs help to achieve this protection. Decision-makers and academics should learn from this empirical knowledge for protection programmes and projects of biodiversity.


Drug teratogenicity has been demonstrated experimentally for more than 20 years. However, the clinical implications of the experimental results have only been fully recognized since the discovery of the thalidomide-induced embrxopathies. At that time, the potential danger for the fetus of drugs taken by the mother was so overemphasized that therapeutic progress was markedly retarded . Eight years after the thalidomide accidents, experimental and clinical data have led to a less pessimistic appreciation of the teratogenic danger of drugs. It is now understood that very complex conditions have to be fulfilled in order to compete with the various mechanisms which control prenatal development. To produce a congenital malformation, the teratogenic drug not only has to be given at an appropriate dosage, but it also has to act at a very precise moment in the morphogenesis of the embryo. In addition, the embryo must have a suitable genetic susceptibility to be capable of reacting to the teratogenic agent. All of these conditions, which can be easi ly attained in large numbers of experimental animals, occur only exceptionally in the development of the human fetus. No wonder, therefore, that, among the large variety of drugs which are capable of producing congenital malformations in animals, only for a few has it been possible to prove a teratogenic action in humans. The reactions of the fetus to drugs taken by the mother will be examined here under three headings: the teratogenic conditions, the teratogenic agents, and the experimental approach of drug testing.


The thermal stability of the physical, chemical, and electrical properties of W thin films sputter deposited on GaAs were investigated. A variety of characterization methods, including thin film stress analysis, Auger analysis, Rutherford backscattering spectrometry (RBS) analysis, and Schottky barrier measurements showed that the W/GaAs interface remains stable after high‐temperature furnace annealing at 900 °C for 15 min or rapid‐lamp annealing at 1000 °C for 11 s. Some refractory metal compounds were also investigated, including, WSi, WNx, and TaSix. Pure W films produced the best Schottky diode characteristics. The average Schottky barrier height was 0.70±0.009 V across a 2‐in wafer after furnace annealing at 800 °C/15 min. Pure W self‐aligned gate (SAG) metal‐semiconductor field‐effect transistors (MESFET) and digital circuits were also fabricated. Transconductances as high as 300 mS/mm (Lg =1.0 μm) were measured for enhancement mode SAG MESFET's. Circuits were fabricated with SAG MESFET enhancement‐...


Celiac Disease (CD) or gluten sensitive enteropathy is an autoimmune disorder characterised by variable presentations which respond to exclusion of wheat and other gluten containing products [1]. While exclusion of gluten is the corner stone in the management of this entity, newer therapeutic approaches are now being investigated. These include use of elemental diets, oral prolyl-endopeptidases, IL-15 blockage, transamidation of wheat and use of probiotics [2]. With newer therapeutic approaches it might be possible in future for patients with CD to continue to take gluten while remaining symptom free.


A low noise amplifier comprising a first signal amplifier stage, a second stage signal amplifier and a gain control unit. A first signal amplifier stage for receiving an input signal, and outputting a first output signal. The second-stage signal amplifier coupled to the first signal amplifier stage for a first output signal, the output of the second output signal, a second output signal wherein the output signal of the second amplifier stage comprising a first output transistor, according to. The first gain control unit comprises a variable resistance element, and the first variable resistance element coupled to the input terminal of the first output transistor to adjust the voltage gain of the second output signals.


The main drawback of orthogonal frequency division multiplexing (OFDM) systems is the high peak-to-average power ratio (PAPR), which leads to performance degradation and power inefficiency. Tone injection (TI) is a distortionless technique that can reduce PAPR efficiently without incurring data rate loss or extra side information. However, optimal TI requires an exhaustive search over all combinations of possible constellations, which is an NP-hard problem. Suboptimal algorithms, achieving different tradeoffs between the PAPR reduction and complexity, have thus been developed. In this paper, we introduce a novel parallel tabu search algorithm for TI. Simulation results show that the proposed algorithm achieves significant PAPR reduction while maintaining low complexity.


Feminists have coined the term 'compulsory monogamy' to describe the deeply normalised status of coupling, especially for women. To say that monogamy is compulsory is to call attention to constraints on our ability to imagine alternatives. The visibility of alternative relationship models can challenge monogamy's grip on our imaginations, but it can also reinforce its status. This paper explores how normative femininity functions to code monogamous and non-monogamous possibilities as desirable and undesirable, respectively. While both are possible, monogamy is reinforced as healthy adult sexuality – for women and men – through the policing of femininity. The paper grounds this discussion in a reading of a film – Two Girls and a Guy – in which the possibility of a non-dyadic relationship is on the table and at the same time rendered implausible. The analysis has implications both for further unpacking cultural investments in coupling and for resisting compulsory monogamy.


The invention discloses a dispersible tablet of codonopsis pilosula and bergamot. The dispersible tablet comprises the following components in parts by weight: 200-300 parts of Chinese yam, 200-300 parts of Chinese angelica, 200-300 parts of the codonopsis pilosula, 100-200 pats of the bergamot, 40-60 parts of microcrystalline cellulose, 0.12-0.32 part of trametes versicolor extract, 0.12-0.32 chitosan, 1-2 parts of vitamin C, 0.1-0.2 part of calcium carbonate, 100-170 parts of mannitol, 10-15 parts of sucralose, 10-50 parts of superfine silica powder, 3-5 parts of carboxymethylcellulose, 55-80 parts of sodium carboxymethyl starch, and 4-6 parts of magnesium stearate. The dispersible tablet has the effects of enriching blood and replenishing qi, increasing the bone mineral density, enhancing the immunity and the like. The dispersible tablet is suitable for postpartum abdominal pain, and the symptoms include gripping pain of the lower abdomen, comfortable feeling when the lower abdomen is pressed, little and light lochia, dizziness, tinnitus, fence dregs, pink tongue, thin fur and the like; the dispersible tablet is used for auxiliary rehabilitation.


In the last decades, mathematical models have become of great importance in the context of diabetes treatment planning. Several modeling approaches based on first principles or input-output techniques have been proposed. However, a relevant open problem common to all these approaches is that they are not able to recover or to systematically account for the various unmeasured signals that affect a diabetic patient (e.g., food, physical activity, and emotions). A novel blind identification approach is introduced in this brief, allowing us to model type 1 diabetic patients and to effectively recover the unmeasured input signals. The approach is applied to an experimental study regarding identification and prediction of the blood glucose concentration in five type 1 diabetic patients.


Recent theorizing on second language (L2) motivation has proposed viewing motivation as a function of the language learners' vision of their desired future language selves. This would suggest that the intensity of motivation is partly dependent on the learners' capability to generate mental imagery. In order to test this hypothesis, this study investigates whether learner characteristics are related to sensory and imagery aspects with indices of the strength of the learners' future L2 self-guides (ideal and ought-to L2 selves) and how these variables are linked to learning achievement in two target languages, English and Mandarin, assessed both by self-report and objective measures. One hundred seventy-two Year 8 Chinese students (ages 13–15) completed a questionnaire survey, and the results reveal several significant associations between the future self-guides and intended effort and actual grades, including a consistently positive relationship between the ideal self and the criterion measures. The findings also confirm the multisensory dimension of future self-guides, suggesting the importance of a broad imagery capacity (including both visual and auditory components) in the development of individuals' future self-identities. Finally, the ideal-self images associated with different languages were shown to form distinct L2-specific visions, which has various implications for future research with regard to the potential positive or negative interaction of these self images.


Abstract: Nowadays, holdup has become one in every of the foremost critical problem thanks to increasing population and automobiles in cities. Hold up causes delay and stress for drivers and increases pollution and carbonic acid gas emissions. The traffic controller is one in all the critical factors affecting the traffic flow. This paper proposes a control system supported image processing including video processing within which traffic signals change accordingly the density of traffic and it will make use of Arduino UNO board for Traffic Lights, Emergency Vehicles and Barrier. A video camera and traffic lights are interfaced with Arduino UNO. The video is processed and Arduino enables the traffic lights to vary when required. Along with this, barrier at zebra crossing and emergency vehicle passing are the best concept for today's smart city. Keywords: Image Processing, Time, Signals, Emergency Vehicles, Barrier


Electrical resistivity measurements of the system Mn5(SixGe1x)3 are performed over the complete concentration range 0 ≦ x ≦ 1, between 4.2 and 350 K. The phenomenological law (ϱ—ϱ0)/ϱ0 = ATn is deduced from the low temperature curves ϱ(T). The exponent n is about 2 for all concentrations in the range 0 ≦ x < 1. The values obtained for A show that three domains of concentration can be distinguished: 0 ≦ x < 0.4; 0.4 ≦ x < 0.8; 0.8 ≦ x ≦ 1 with different magnetic ordering. In the range 0 ≦ x ≦ 0.9 the curves ϱ(T) are characterised by a break in their slope corresponding to the transition order—disorder. The behaviour of the Mn5Si3 compound is very different, the ϱ(T) curve shows two successive minima at 74 and 105 K, the latter singular point corresponding to the Neel temperature.

Des mesures de resistivite electrique ont ete effectuees entre 4,2 et 350 K dans l'intervalle de concentration 0 ≦ x ≦ 1 du systeme Mn5(SixGe1x)3. Une analyse des courbes obtenues a basse temperature nous a permis de deduire la loi phenomenologique suivante: (ϱ — ϱ0)/ϱ0 = ATn. l'exponant n est de l'ordre de 2 dans tout intervalle 0 ≦ x < 1. Les valeurs obtenues pour A permettent de distinguer trois regions de concentration 0 ≦ x < 0,4; 0,4 ≦ x < 0,8 et 0,8 ≦ x ≦ 1 qui se manifestent par des interactions magnetiques differentes. Dans le domaine 0 ≦ x ≦ 0,9 les courbes ϱ(T) presentent toutes une rupture de pente correspondant a la disparition de l'ordre magnetique. Le comportement de Mn5Si3 est tres different: la courbe ϱ(T) presente deux minima successifs a 74 et 105 K, le dernier correspondant a la temperature de Neel.


The concept of isotropically random mosaic introduced by Pielou, is recalled. The notion of anisotropically random mosaic with respect to a point is defined. An example is given.


In Part 1 of this series, we formulated a porous electrode model including multiple lithium-insertion species and associated electro- chemical and homogenous reactions. In this paper, the multi-species multi-reaction (MSMR) model is used to simulate linear-sweep voltammetry (LSV) data of a porous electrode of spinel lithium manganese oxide (LMO) at different scan rates, and values of trans- port, kinetic, and thermodynamic parameters are fit to the measured data. Twenty model parameters are optimized to simultaneously fit the slowest and fastest sweep rates. The optimization is computationally intensive, but the calculation times were reduced by almost one half using a perturbation formula valid at the lowest sweep rate, developed in Part 1, together with numerical solutions at higher sweep rates. A sensitivity analysis determines the importance of different model parameters on the results. The fitting is most sensitive to the values of the Open Circuit Voltage (OCV) and it was necessary include a small amount of hysteresis, so that the OCV is slightly different on forward and backward scans. The next most important fitting parameter was the solid phase diffusion coefficient. Of smaller importance are the kinetic parameters and ohmic losses in the solid and liquid phases of the electrode. Part 2 of a two-part series on fitting material parameters to voltammetry data for a porous electrode of spinel lithium manganese at different scan rates. multi-species, multi-reaction


The impact damage response of balsa core sandwich composite plates with S2-glass/ epoxy reinforced facesheets is evaluated by impacting them with a spherical steel projectile at single impact locations. The impact damage can significantly reduce the structural integrity and load bearing capacity of a composite structure. Under high velocity impact loading, laminated composites experience significant damage causing fiber breakage, matrix cracking and delamination. Energy absorption and delaminations from high velocity impacts with spherical projectile of .30 caliber is discussed. Finite element modeling was used to gain insight into failure modes, energy absorption, and damage prediction. During high velocity impact, composite laminates undergo progressive damage and hence, Material Model 162, a progressive failure model based on Hashin's criteria, has been assigned to predict failure of the laminates. The laminates, the projectiles and the balsa wood core are meshed using brick elements with single integration points. These results were then compared with experimental data obtained from three layer S-2 glass/epoxy facesheets balsa core sandwich structures. An excellent correlation between experimental and numerical results had been established.


This paper introduces the problems of production system before technical innovation in Gaozhuang Preparation Plant;the technical process of technical innovation project of production system of pressureless feed three products dense-medium cyclone that consumed 4 millions yuan and processing power is 214 ton feed coal per hour,and the benefit achieved by adjusting clean coal index in jigging and dense-medium separation paralleled connection after technical innovation.


June 24, 2008

Dear Dr. Harris:

Your editorial entitled "Plantar Fasciitis: What's an Evidence-Informed Consumer To Do?"1 is a suitable companion piece to your controversial 2005 editorial.2 It was intended to demonstrate to clinicians how to conduct research using widely available Internet tools. What is interesting is that your self-styled plantar fasciitis treatment program does not actually include any physiotherapy. Beyond perhaps one session for a therapist to diagnose the problem, show you stretches, and send you to the pharmacy for your orthotics, your recommendation to an "evidence-informed consumer" is to deal with the problem independently. This is remarkable, to say the least, coming from the chief editor of our national journal.

Your recommendation may preserve your integrity in a purely research-oriented sphere, Dr. Harris, but have you thought of the implications of this? What you have stated is, in effect, that what I and fellow clinicians are doing is insufficiently researched, so therefore not worthy of your time. Are you intending to produce a regular feature in Physiotherapy Canada, in which you conduct your searches, and conclude that taking medication, reducing activity, and doing a home stretch or two for a gamut of musculoskeletal disorders is a "smart choice" for the health care consumer? If government agencies, third-party insurers, and consumers follow your direction, and do not pay for or attend treatment because literature searches do not reveal randomized controlled trials and strong evidence of efficacy, how would this affect our profession?

Please understand: I am not an opponent of evidence-based practice (EBP). I understand the need for studies supporting our management of orthopaedic conditions, and ones that suggest improvements to practice and directions for future care. Your citations of studies about fascia-specific stretching and orthotics are well taken. There are definite limitations to EBP, however, and I think you should reread Eric Baker's excellent response3 to your previous contentious editorial about EBP1 – you appear to have forgotten some of the thoughtful points he made.

All the best in your recovery! I sincerely hope you do not end up in the same situation as so many of my clients over the years, who have followed the same prescription of anti-inflammatories and reduced activity. They present in the clinic at 3 or 4 months post–flare up, with sore stomachs to go along with the sore heels, courtesy of the medication that has not really worked, frustrated at their lack of progress. I tell them to stretch, to wear their orthotics, advise them of the biomechanical problems they had before or have developed from limping around, and recommend the ultrasound that will almost certainly help. A great majority of them do find benefit. Perhaps your scientific rigour will relax if you end up in their situation and discover your heel pain has not heeded the evidence and now your treatment options are few. My card is enclosed – first treatment on the house.


The author discusses the musical trajectories of several avant-garde English composers, in particular their increasing attention to works for piano. She analyzes the historical roots of this new movement and its relation to the experimental tradition from which it developed, finding continuities perhaps not often recognized or understood.


PANDA is a large-scale, low-pressure test facility for investigating passive decay heat removal systems for the next generation of LWRs. In the first series of experiments, PANDA was used to examine the long-term LOCA response of the Passive Containment Cooling System (PCCS) for the General Electric (GE) Simplified Boiling Water Reactor (SBWR). The test objectives include concept demonstration and extension of the database available for qualification of containment codes. Also included is the study of the effects of nonuniform distributions of steam and noncondensable gases in the Dry-well (DW) and in the Suppression Chamber (SC). 3 refs., 9 figs.


ABSTRACT Recent critiques voiced by students in both the Global South and North have turned attention to the ways in which higher education practices have been informed by, and continue to perpetuate, a series of assumptions that favour particular epistemological perspectives. Across the world, students have criticised universities for the content of their curricula, institutional cultures, and pedagogic practices that perpetuate the attainment gap and exclusion. In response, curricula and pedagogic change is being debated and promoted on campuses. This introductory article lays the theoretical groundwork for a volume that brings decolonial theory into concrete engagement with the structural, cultural, institutional, relational, and personal logics of curricula and pedagogic practice. The article examines the relationship between decolonisation as a theoretical concept, and the practices of decoloniality unfolding in pedagogical practice.


In this paper we argue that gestures based on non-accidental motion features can be reliably detected amongst unconstrained background motion. Specifically, we demonstrate that humans can perform non-accidental motions with high accuracy, and that these trajectories can be extracted from video with sufficient accuracy to reliably distinguish them from the background motion. We demonstrate this by learning Gaussian mixture models of the features associated with gesture. Non-accidental features result in compact, heavily-weighted, mixture component distributions. We demonstrate reliable detection by using the mixture models to discriminate non-accidental features from the background.


Scheduled railroading refers to creating dock-to-trip plans for individual railroad shipments. It is not simply a matter of scheduling terminal-to-terminal transit for trains. The concept has been around since the late 1980s and is being effectively used at the Canadian National Railway Co. (CN). This article describes how scheduled railroad can help keep a railroad on a continuous-improvement track.


BACKGROUND
To analyze the factor structure and psychometric properties of the TFEQ in a morbid obese Spanish sample of bariatric surgery candidates.

METHOD
Multi-trait/ multi-item analyses and alpha coefficients were conducted to test the convergent /discriminant validity and the internal consistency reliability. Principal components analyses (varimax) were used to explore the factor structure. Sub-group factor analyses by gender, age and body mass index (BMI) were conducted to identify unstable items.

RESULTS
The internal structure of the original TFEQ factors was unsatisfactory, especially the Disinhibition Scale. Most Disinhibition and Hunger items were grouped on one factor labeled "Dysregulation Eating". Cognitive Restraint was split into two factors. The first one, related to the behavioral component of Restraint, labeled "Restrained Behaviour" and the second one related to weight and eating concerns called "Predisposition to Restraint".

CONCLUSIONS
The original factor structure of the TFEQ was not replicated. A revised 23-item instrument, representing the three new derived factors is offered as a valid screening instrument for severely obese patients.


Objective To summarize the experience of 5 patients with cardiac anomaly complicating thoracic deformity neoplasty by thoracoscope completely and auxiliary thoracoscope.To discuss the thoracoscopic application in cardiac anomaly complicating thoracic deformity neoplasty.Methods From May 2010 to November 2011,atrial septal defect complicating pectus excavatum neoplasty in 2 cases,ventricular septal defect complicating pectus excavatum neoplasty in 2cases,ventricular septal defect complicating pectus carinatum neoplasty in 1case by thoracoscope.Men in 3cases,women in 2cases,age 2.5 years~15 years old,weight 15~35 kg.Results Without expanding incision and secondary open-chest bleeding intraoperatively,the time of the operation 3.5 to 5.5 h,the average 4.6 h,extracorporeal circulation time 50~70min,the average 45min,aorta blocking time 30~45min,the average 36min.Postoperatively patients recovered well and were satisfied for treatment effect.Conclusions It was safe and effective that treated cardiac anomaly complicating thoracic deformity neoplasty by thoracoscope and auxiliary thoracoscope.


High-performance CoO–Cu2 O/SiC is prepared for the gas-phase aerobic oxidation of benzyl alcohol of benzaldehyde, which delivers much higher catalytic performance (92% benzyl alcohol conversion and 99% selectivity at 260 °C) than the solo CoO/SiC and Cu2
 O/SiC. TEM image indicates that the small size CoO and Cu2 O nanoparticles are homogeneously distributed on the support. Control experiments indicate that Cu2 O–CoO interfaces are responsible for their better reaction performance.


A description is given of a test for determining the ouflow of the aqueous humour. The test consists of compressing the eyeball with a metal funnel attached near the limbus of the cornea by suction. The intraocular pressure increased in this way is kept constant during the test by increasing the suction. The inraocular pressure value is continuously conrolled by an applanation tonometer. The results are based on the amount of extra suction that is necessary to keep the inraocular pressure consant.


angela Senander's short book on scandal is valuable for scholars and nonscholars alike. She demonstrates how scandal, whose etymology is "stumbling block" (to one's faith or trust), has been employed by the church as a catalyst and as a rationalization for many decisions. She ultimately concludes that, ironically, many attempts to eliminate threats of scandal have historically caused even greater scandals, as best illustrated in the Roman Catholic Church's institutional attempt to avoid scandal in the case of clerical sexual abuse (25). Senander begins with a sociological analysis of scandal's four components: the act, the agent, the announcer, and the audience. This sociological analysis, offered with biblical texts to illustrate each component, provides the background for her discussion of various "sources of scandal," including divisions within the Church, certain Church teachings, and the Church's public stance when confronted with scandal. Her main focus is to examine these "obstacles to faith" from a theological and catechetical perspective. She begins with aquinas, who defines scandal as "something less rightly done or said that occasions another's spiritual downfall" (15). She notes his observation that not only can one's wrong actions tempt another to sin but so can actions that only appear wrong, even if fundamentally good (15). This latter category aquinas attributes to either the malice or ignorance of the audience, labeling it "passive" scandal, and urging education of the ignorant to combat it (17). Senander points out that the description of scandal by both Trent and vatican ii has slightly changed because of such events as dissension over Humanae Vitae; legalization of abortion, divorce, and euthanasia; and cases of clerical sexual abuse. The wording of the Catechism shifted from the traditional "word or deed" to "attitude or behavior." in response, Senander raises the problems of how one could know another's "attitude" and the possibility of indicting the agent for another's malice in misinterpreting potentially good acts as scandalous (e.g., making Jesus responsible for leading the Pharisees into temptation by proclaiming the kingdom of god). each of Senander's considerations relating to scandal could serve as the basis for much lengthier treatises. For example, she challenges the Catechism's endorsement of withholding truth to avoid scandal (27), and questions the


The flow control component of a transport layer protocol regulates the natural data transmission rate of an application to match the service rate offered by the network. In this paper, we study the problems that arise when a flow control protocol has to deal with long delays in receiving information about network state, and has large amounts of data transmitted but unacknowledged. We describe three representative flow control protocols, and study their behavior on a suite of three benchmark scenarios. Our simulations indicate that in networks with large delays, protocols that are insensitive to the state of the network, or that require multiple round trip times to attain the optimal transmission rate, will perform poorly. The packet-pair protocol, which avoids these problems, is shown to perform well under rather adverse conditions.


This paper analytically derives the torque density expression from the perspective of active material mass for surface-mounted permanent-magnet machines with non-overlapping windings. Based on this, the influence of key parameters, including the split ratio, aspect ratio and PM thickness to air-gap length ratio (hm/g), on the torque to mass ratio (TMR) is investigated under fixed copper loss and rated torque conditions. Guidance of selecting these parameters is given. Moreover, further analysis is carried out when the volume and rated torque are flexible in order to verify applicability of conclusions. Results show that TMR is a concave function of the split ratio, which means the split ratio at ends within the adequate scale can achieve the lightest machine. In addition, TMR increases and then may level off as the machine becomes flatter. Besides, a negative correlation is found between TMR and hm/g. The analytical results are validated by finite element analysis.


So much of my travelling is done on foot, that if I cherished betting propensities, I should probably be found registered in sporting newspapers under some such title as the Elastic Novice, challenging all eleven–stone mankind to competition in walking. My last special feat was turning out of bed at two, after a hard day, pedestrian and otherwise, and walking thirty miles into the country to breakfast. The road was so lonely in the night, that I fell asleep to the monotonous sound of my own feet, doing their regular four miles an hour. Mile after mile I walked, without the slightest sense of exertion, dozing heavily and dreaming constantly. It was only when I made a stumble like a drunken man, or struck out into the road to avoid a horseman close upon me on the path—who had no existence—that I came to myself and looked about.


The Krasnaya Gorka grave field located in Central Tuva on the left bank of the Ulug-Khem (Yenisei) in the Bai-Bulun area was studied by the Tuva archaeological expedition of the Institute of the History of Material Culture of the Russian Academy of Sciences (St. Petersburg) in 2015. The article presents a full publication of the materials of two Objects (Nos. 3 and 5) of the Krasnaya Gorka-19 monument, which belongs to the Turkic period. Object number 3 – undermound burial in the grave with two accompanying horses and the stele installed in 3 m to the east – south-east made of a "deer" stone, dug upside down. The burial is not robbed, all the equipment is presented. Anthropological and paleozoological determinations are given, a brief interpretation of the complex is given and its place is noted in the circle of synchronous monuments of Tuva and Central Asia. Special attention is given to the carved signs (possibly tamgas) on the central horn overlays on the bow. There is a lack of direct analogies to these signs in the Orkhon and Yenisei alphabets, as well as in the body of well-known tamgas and tamga-like signs of Tuva and adjacent territories.


I'm a student from Longkou Middle School.The things here were bad when I began to study in this school over two years ago.There was neither enough water nor green trees.What Was worse,the students didn't have a good condition to study.


Each Android application requires accumulations of permissions in installation time and they are considered as the features which can be utilized in permission-based identification of Android malwares. Recently, ensemble feature selection techniques have received increasing attention over conventional techniques in different applications. In this work, a cluster based voted ensemble voted feature selection technique combining five base wrapper approaches of R libraries is projected for identifying most prominent set of features in the predictive modeling of Android malwares. The proposed method preserves both the desirable features of an ensemble feature selector, accuracy and diversity. Moreover, in this work, five different data partitioning ratios are considered and the impact of those ratios on predictive model are measured using coefficient of determination (r-square) and root mean square error. The proposed strategy has created significant better outcome in term of the number of selected features and classification accuracy.


The present study is a comprehensive analysis of the cultural dimension "distance towards power" in Suceava county organizations, developed in accordance with the processing research methodology of COMOR. The COMOR Project – The managerial behaviour in the organizations from Romania is a complex exploratory research carried out at a national level, in economic organizations from all fields of activity, and it was initiated in 2008 by the Scientific Society from Romania. Its objective is to identify the cultural dimensions that characterize the Romanian organizational management, the analysis of the way in which leadership is perceived, as well as the influence exercised by the national culture on the organizational practices and the behaviour of the managers. Key-Words: COMOR project, cultural dimension, managers, managerial behaviour, distance towards power, scores, hierarchy, organizational management


: This paper aims to prove the influence fundamental factors that consist of profitability, liquidity, leverage and activity to towards the stock price at mining companies listed on Indonesia Stock Exchange in 2013-2015. Profitability was measured by Return on Asset (ROA), liquidity was measured by Current Ratio (CR), leverage was measured by Debt to Equity Ratio (DER) and activity was measured by Total Asset Turnover (TATO). This research used descriptive study with verification method and documentation technique for collecting data. This research also used secondary data which financial report and annual report from mining companies in 2013-2015. The technique for collecting sample is based on purposive sampling to get 24 companies in three years from 2013 to 2015 with 72 observation data. The statistic analysis is used panel data regression. The conclution of this research is in a simultaneously fundamental factors that consist of profitability, liquidity, leverage and activity have a significant effect on stock price. In partially profitability and activity has positive significant e ffect on stock price, liquidity hasn't positive significant effect on stock price and leverage has negative significant effect on stock price.


Background: It is predicted that artificial intelligence (AI) will transform nursing across all domains of nursing practice, including administration, clinical care, education, policy, and research. Purpose: This study examined the impact of an AI course in the nursing curriculum on students' medical AI readiness. Design and Methods: This comparative quasi-experimental study was conducted with a total of 300 3rd-year nursing students, 129 in the control group and 171 in the experimental group. Students in the experimental group received 28 hours of AI training. The students in the control group were not given any training. Data were collected by a socio-demographic form and the Medical Artificial Intelligence Readiness Scale. Results: An AI course should be included in the nursing curriculum, according to 67.8% of students in the experimental group and 57.4% of students in the control group. The mean score of the experimental group on medical AI readiness was higher (P < .05) and the effect size of the course on readiness was −0.29. Conclusions: An AI nursing course positively affects students' readiness for medical AI.


Consider the following boundary value problem in the exterior space 5'd~1 = {x e : |x| > 1} of a sphere in two and three dimensions (d — 2,3): Given a vector field D : Sd~1 —> we ask for all harmonic vector fields B : Sd~l —* IRd which decay at least as fast as a dipole field at infinity and are parallel to D on 5d_1; i.e. there is / : Sd~l —> R such that B = / D. For d = 3, this problem is related to the problem of reconstructing the geomagnetic field outside the earth from directional data measured on the earth's surface. The question for uniqueness or non-uniqueness is of particular interest here. In this paper we characterize the solution space of the boundary value problem as orthogonal complement of a certain set of functions determined by the vector field D in an appropriate Hilbert space. Based on the Hilbert space approach we determine and its dimension dim for certain classes of vector fields D. In particular, we find in d = 2 for those fields D^v which are obtained by restricting a 2jV pole field on S1, dim VpN — 2(N — 1) + 1. This result is robust in the sense that perturbations of Djy which are small in a certain norm do not change the dimension of the solution space. In d = 3 we consider only the axisymmetric situation. Here, we find in the case that D is given by polynomials of order not larger than N the upper bound dim < N and in the 2^—pole case dim = N. For N = 1 (dipole field) the result is proved to be robust, which implies uniqueness of the boundary value problem for all vector fields D close to Di. For Djv with N > 2 it is shown that uniqueness can be enforced if either the Hilbert space is truncated or if stronger decay conditions at infinity are imposed.


A series of alkyl carbamate ionic liquids (ILs) have been prepared from CO2 and an amine, including a number of novel members of the family, in order to provide a range of solvent properties that have the potential to improve the sustainability of natural product extractions. Whereas the dimethylcarbamate ionic liquid is a low boiling hydrophilic and water-soluble liquid, the higher homologues become water immiscible but remain easily distillable. By way of example, it is shown that the dipropylcarbamate analogue was optimal for the selective extraction of curcumins as active pharmaceutical ingredients. Product separation from these ILs can be achieved by complete distillation of the ILs.


Commitments from Festina France on its distribution agreements, accepted by the French Competition Council (Conseil de la concurrence) in a decision of 24 July 2006, are the first ones to be…


PROBLEM TO BE SOLVED: To provide a digital video camcorder in which a high picture quality moving image and a low bit rate moving image are simultaneously recorder on respective recording media with respect to one and the same photographing target. SOLUTION: The digital video camcorder includes: an imaging device for applying photoelectric conversion to light image formed by a lens; an image pickup processing circuit for converting a photoelectric converted electric signal into a digital video signal; a first generating means for generating a moving image signal having a subband component by applying hierarchical coding to the digital video signal converted by the image pickup processing circuit; a second generating means for generating a moving image signal having a full band component; first and second recording means for simultaneously recording outputs from the first and second generating means onto the plurality of respectively different recording media; and a reproducing means for respectively reproducing the moving image signals of the subband and the full band from the signals recorded on the plurality of recording media. COPYRIGHT: (C)2004,JPO


Made in 1926, the first film version of The Great Gatsby has sadly been lost, but contemporary reviews and a surviving trailer give a flavour of what it must have been like


I address here the question what sense to make of the idea that there can be thought prior to language (both in ontogeny and among nonlinguistic animals). I begin by juxtaposing two familiar and influential philosophical views, one associated with the work of Paul Grice, the other associated with the work of Donald Davidson. Grice and Davidson share a broad, rationalist perspective on language and thought, but they endorse conflicting theses on the relation between them. Whereas, for Grice, thought of an especially complex sort is a precondition of linguistic meaning, for Davidson, there can be no genuine thought without language. I argue that both views present us with unpalatable alternatives concerning our understanding of the natural origins of objective thought and meaningful language. Drawing on what I take to be key insights from Grice and Davidson, I then lay out some broad desiderata for an intermediate position. I finally turn to a certain form of nonlinguistic communication of the sort of which both prelinguistic children and languageless animals are capable, viz., expressive communication. I propose that a proper appreciation of the character and function of expressive communication can help us trace the outlines of the desired intermediate position.


The lack of statistical information, trustworthy market, and the great dispersion that has existed in public and private entities in Mexico, has halted the concentration of relevant information for making strategic decisions. With that, the thematic factor of the market investigation was analyzed to find out acceptations of touristic products and services. Also, the collection of information through a methodic model consisted of a market study combined with empirical factors. On the other hand, the subject of the study was focused on environmental factors of the touristic sector of the Kino Bay region, Sonora, Mexico. Considering the evaluation of the demand for recreational activities offered by the touristic industry in the community, the investigation allowed a clear establishment of the behaviors of the consumers and their necessity for recreational activities that interact with the environment.


Thank you for reading histochemistry of secretory processes. As you may know, people have look hundreds times for their chosen books like this histochemistry of secretory processes, but end up in malicious downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they juggled with some malicious bugs inside their desktop computer. histochemistry of secretory processes is available in our book collection an online access to it is set as public so you can download it instantly. Our digital library saves in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the histochemistry of secretory processes is universally compatible with any devices to read.


In Ciona intestinalis, sperm penetration through the egg vitelline coat is an essential event of fertilization. We investigated whether trypsin‐ and chymotrypsin‐like enzymes are involved in this event. Inhibitors and peptide substrates for chymotrypsin‐like enzymes blocked the overall process of fertilization in a concentration‐dependent manner. The inhibitory activity was specifically exerted on the step of sperm penetration. Chymotrypsin‐like protease activity was identified in spermatozoa with the fluorogenic synthetic substrate Suc‐Ala‐Ala‐Phe‐AMC, which was the most effective substrate in blocking sperm penetration. These data indicate that a chymotrypsin‐like protease activity is a sperm lysin of Ciona intestinalis.


Three Cd(II)-based coordination polymers 1–3 with unique structures and topologies have been successfully constructed under solvothermal conditions by use of a newly designed N-containing rigid triangular ligand tris(4-(4H-1,2,4-triazol-4-yl)phenyl)amine (TTPA-4), wherein the structural interpenetration can be modulated by aromatic dicarboxylate coligands including thiophene-2,5-dicarboxylic acid (TDA) and terephthalic acid (TPA). Without using coligands, a noninterpenetrating porous 3-D network of 1 with nia topology was obtained. With the aid of the V-shaped TDA coligand, a 4-fold interpenetrating 3-D network of 2 resulted that is built from (2,3,7)-connecting (42.6)(188.8.131.52.124)(4)2 net. In the presence of the linear TPA auxiliary ligand, an 8-fold interpenetrating 3-D network of 3 was produced that is assembled by 3-connecting uninodal srs net. Particularly, compound 1 displays interesting dual function as the result of its unique structural attributes, which not only shows superb sensitivity for ...