The health service of EU member states facing numerous challenges. Hospitals have a catastrophic shortage of medical personnel; meanwhile, the demand for medical services caused by the SARS-CoV-2 virus is increasing. Hospitals' pursuit of recruiting staff with a high level of professional education is more likely to be successful with potential candidates in a competitive talent market in institutions where a cultural organization, innovative treatment as a patient-centered approach is included in top priorities. The survey was conducted in the pre-COVID time with the use of the proprietary questionnaire in a traditional way. 204 employees of the Prof. dr Stanisław Popowski Regional Specialized Children's Hospital in Olsztyn were the respondents. The paper uses the r-Pearson correlation analysis. IBM®SPSS®Statistics, version 18.104.22.168, was used to develop the correlation results. After verification of the research hypotheses, it was shown that there is a statistically significant relationship between inappropriate activities of employer branding and reduced employee retention. It has been demonstrated that there is a discrepancy in the offered and actual working conditions. The discrepancies concerned the atmosphere at work (31.4%) and the inability to develop a career path (8.3%). 19.1% are willing to change jobs due to inadequate remuneration. For the respondents, factors important in choosing a workplace included remuneration, organizational culture, and the availability of the benefits package. One hypothesis was confirmed, another was partially confirmed.The proposals presented in the paper could significantly contribute to shaping a good image of hospital employers and increasing employee satisfaction.
AcknowledgmentThe study was conducted at the Prof. dr Stanisław Popowski Regional Specialized Children's Hospital in Olsztyn.


rules and from which semantic content can be derived. The alien might not have any a priori clue as to how human languages are expressed, parsed, and give rise to semantic meaning. If the alien itself has language, it might adopt a protocol for human language discovery, starting, for example, with self-identification. This made me wonder whether some of our unsupervised patterndetection mechanisms used in machine learning could be used to discover plausible phonemes in bird songs without making arbitrary judgments as to how to segment the patterns by pitch, duration, and repetition. In another lecture by Con Slobodchikoff, the warning signals of prairie dogs were analyzed and correlated with the arrival of identifiable predators. Evidence was offered from which we could infer the signals had sufficient descriptive capacity to distinguish among various predators, their size, location (for example, ground direction or airborne), and possibly other characteristics. Other efforts analyzing gray parrots


Placenames of Alava with anthroponymical bases and ending in –iz, -ez and –ona / -oaIn this work we analyze the alavese toponyms that are based on a person name, whose origin is usually Latin, in addition to these toponyms having suffixes like –iz (Basque and Spanish), -ez (Spanish) on the one hand, and –ona (Spanish), -oa (Basque) on the other. After dealing with what various authors have claimed about the origin of said suffixes, we propose the Latin genitive ending –(o)nis for –ez, -iz, albeit the genitive form –ici of the suffix –icus can not be discarded here either. It is clear, in any case, that from some point on the –(i)(t)z suffix that denoted ownership became an independent suffix on its own right, being subsequently applied to native names, which shows us that it is not always necessary to resort to Latin. On the other hand, regarding the suffix –ona, -oa, which also denotes ownership, we propose, following what other authors have claimed about its origins, the accusative ending –one(m) as the original form, which appeared first in names declined following the pattern –o, -onis and eventually became adapted to the declension –ona, -onae.


Organisations are intricate systems with various components interacting in diverse ways, making it impossible for any member, including the directors and the CEO, to have a complete picture of the organisation, despite all efforts to collect data and information. Consequently, all members inevitably focus on partial observations of what happens and fill in the gaps of unobserved reality with their own beliefs and assumptions.


The tremendous changes of time and space which arose by globalization bring the sense of intensity and tightness,thus lead to the difficult position of national spiritual home.Bewilderment and challenge in the era of globalization,as well as multiple and symbiotic value need renaissance and reconstruction of national spiritual home,therefore we can find spiritual backbone and vitality for the development of a nation.The awareness and verification of life consciousness which brought by cultural value critique in the theory of Marxist critique of modernity present the wise pursue of spiritual ontological domain.The examination and expectation of daily life critique to life world imbue the virtue consideration of the significance of spiritual home.And the longing and construction of ecological harmony of ecological critique cast light on ultimate pursuit of spiritual home.


Abstract : The hybrid threat construct is the future model that the US Army will use to focus their training efforts. Units will develop techniques and capabilities to defeat this model, both at home station and Combat Training Center (CTC) rotations. Although considerable discourse highlights that this is a new way of war, history says otherwise. The hybrid threat concept is not a new form of warfare; history marks multiple examples and variations of this construct. From Napoleon's Peninsular Campaign (1808 to 1814) in Spain to the 2006 Hezbollah-Israeli War, hybrid threats are prevalent on the battlefield. Furthermore, military engineers served with distinction in hybrid threat environments, significantly enhancing a force's capability in a conflict. Military engineers are capable of supporting operations against a hybrid threat, through synchronized and simultaneous actions. The integration of combat, general, and geospatial engineering along with the engineer line of efforts will support operations in this environment. Furthermore, military engineers enable the application of operational art, which supports commanders as they combat hybrid threats to achieve their desired state.


Once again the Stirling Prize shortlist is out, and once again one sees a varied lot of building typologies and approaches. Of course the House in Essex deserved to be on the list, but instead of beating that drum, I am going to look at the shortlist and rate them in terms of their response to their urban (or rural) context.


Summary The available archaeobotanical evidence from Viking Age sites lying within the boundaries of present day Denmark is summarized and commented upon. The exploitation of both cultivated and wild plant resources is dealt with under the headings - the agrarian economy (crops and weeds), imported plants, collected food plants, brewing, medicinal plants, religion and ritual, wetlands and heaths.


There are about 60,000 Ethiopian Jews living in Israel today, many of whom emigrated in two governmentsponsored rescue missions. The first of these, Operation Moses, in 198485, secretly brought 6,500 Jews who had fled from Ethiopia to Sudan. The second, Operation Solomon, in 1991, airlifted 14,000 Ethiopian Jews from Addis Ababa to Israel in a span of 36 hours. In the summer of 1997 I interviewed nine pairs of Ethiopian Jewish mothers anddaughters in 1srael.Their community, called Beta Israel, traces its history back to the liaison between the Queen of Sheba and King Solomon or perhaps to the lost tribe of Dan.1 Because of their isolation from the other Jewish communities around the world they have retained a Jewish heritage similar to biblical Judaism but which is also informed by the African milieu. The stories of mothers (aged 38-75) and daughters (aged 20-32) reflect the construction of their identities as women and as Jews and demonstrate women's strength and survival skills. As women refugees fleeing war, famine, and religious oppression, they relate tales of resistance and survival against harrowing circumstances and conditions. The daughters' repeated enjoinders that their mothers' heroism be transvictims or refugees but as agents of their own survival and of the survival of their children.


This paper enumerated the definition and main factores of the hospital core competence,pointed out the function of medical equipment purchase work at promoting hospital core competence and discussed the purchase principle,purchase procedure of the medical equipment.Finally,the paper proposed that only by developing and useing advanced function of medical equipments we promote hospital core competence.


BACKGROUND
Primary focal segmental glomerulosclerosis (FSGS) is a glomerular disease that frequently does not respond to treatment and progresses to kidney failure. FSGS can be of either genetic origin, caused by mutations in slit diaphragm proteins, such as podocin, or idiopathic origin of unknown cause.

STUDY DESIGN
Case series.

SETTING & PARTICIPANTS
Children with FSGS (aged 3-18 years); 15 with idiopathic and 11 with genetic forms of FSGS.

PREDICTOR
Genetic versus idiopathic forms.

OUTCOMES & MEASUREMENTS
Differentially expressed proteins in the plasma proteome, detected using 2-dimensional electrophoresis and identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, Western blot, and liquid chromatography electron spray ionization tandem mass spectrometry for fragmentation and identification of the peptides.

RESULTS
We found 3 very low-molecular-mass (9.2, 6.9, and 4.7 kDa; isoelectric point, 5.7) spots that were present in pooled samples from patients with genetic FSGS, but missing in patients with idiopathic FSGS and healthy individuals. Spots were identified using mass spectrometry as fragments of albumin, 2 of them apparently containing peptides from both C- and N-terminal parts of the whole protein. Proteomic analyses were carried out on all genetic patients individually; of these, 10 of 11 patients had > or =1 albumin fragment detected in the pool. We did not find an evident relationship between type of mutation or clinical status of patients and albumin fragments observed.

LIMITATIONS
Very low-molecular-weight albumin fragments also can be produced by other diseases.

CONCLUSIONS
We describe for the first time the presence of very low-molecular-mass albumin fragments in plasma of patients with FSGS with podocyte protein mutations that are absent in patients with idiopathic FSGS or healthy individuals. Additional studies are necessary to determine whether these fragments could be potential biomarkers to distinguish between genetic and idiopathic forms of FSGS.


Bremsstrahlung cross section calculations are still attracting attention because of the inadequacy of the existing formulae. The Sommerfeld-Elwert formula holds good up to 0.1 MeV. Bethe and Heitler gave a relativistic expression for the bremsstrahlung cross sections using Dirac's electron theory and Born approximation. Coulomb and screening effects were not included in their calculations. Calculations of the bremsstrahlung cross sections using the B-H formula are tedious. Approximations of the B-H formula in the nonrelativistic and extreme relativistic regions exist. But no such approximation is available in the intermediate energy region. An attempt is made to obtain an approximation of the B-H formula in the intermediate energy region. Several approximations are made to reduce the B-H formula into a polynomial in x, the ratio of the photon energy to the total energy of the incident electron. The coefficients of the polynomial turn out to be a long series of terms which are functions of incident electron energy. The validity of the approximate formula in the intermediate energy region will be discussed.


This evaluation examined World Bank and the International Finance Corporation (IFC) support to health financing through lending, investment, policy dialogue, and analytical work. Over FY03–12 the World Bank supported health financing reforms through 188 operations in 68 countries and provided an active analytical program. The IFC delivered a small program with six investments and nine advisory services. The Bank's Health, Nutrition, and Population (HNP) 2007 strategy sees health financing as a comparative advantage for the Bank because of its analytical capacity and multisector nature. The Bank and IFC do not have a joint strategy or strategic approach about the mix of public and private health insurance. The Bank Group did not take an ideological stance in its work in revenue collection and different risk pooling arrangements; rather, it worked within the different country contexts. In line with the Bank's health strategy, the Bank did promote a focus on improved results and performance in health facilities by helping governments and insurers change the way they pay providers. An increasing number of this work is implemented with the support of results-based financing (RBF) operations. The Bank's 2007 health strategy remains valid to guide support to health financing reforms. However, the evaluation finds that key elements of the strategy have proved to be elusive in its implementation, including integration and monitoring and evaluation (M&E). The reasons mainly evolve around capabilities and cross-sector collaboration and are areas for further reflection for the global practices. The factors for successful Bank support include government commitment to address the many challenges in revenue collection for health and risk pooling, ensure pro-poor spending, introduce institutional reforms, and build technical and information capacity. Purchasing needs to be integrated with risk pooling to address financial barriers for poor individuals in accessing care and with public finance to manage adverse effects. Bank analytical work and collaboration across teams helps inform governments in these health financing decisions. These health financing functions heavily depend on information systems, M&E, technical capacity to analyze performance, and government commitment to sustain reforms. The evaluation recognized that reforms in health financing only are insufficient, and additional investments are needed to ensure the supply of health care. But health financing decisions are necessary to influence the provision and use of health care and ensure financial protection. They include decisions about how to mobilize and


Children boarding a Department of Education school bus, probably travelling between Paemako and Piopio School. Taken between 1924-1925. Photographer unidentified.
Note on back of file print reads "`NZ' number plates in use from mid 1924 to mid 1925"
Quantity: 1 b&w original negative(s).


Objective: To evaluate the dimensions of the incisive canal (IC) and incisive foramen (IF) in dentate and maxillary anterior edentulous (MAE) individuals using cone-beam computed tomography (CBCT). Methods: This retrospective, cross-sectional study analyzed dentate and MAE individuals aged ≥ 50 years of both sexes. Using CBCT, we measured the buccal-palatal (BPW) and mesial-distal (MDW) widths of the IF and the length of the buccal cortical (BC) and palatal cortical (PC) bones and the angulation (A) of the IC in relation to the nasal floor. Results: 151 CBCT were analyzed, of which 74 were MAE and 77 dentate with a mean age of 63.3 ± 7.9 and 61.4 ± 9.3, respectively. Compared to the dentate group, the MAE group showed higher MDW of the IF (p = 0.034) and, in the IC, lower BC (p = 0.000), PC (p = 0.006), and A (p = 0.000). In the MAE individuals, the PC was higher in men when compared to women (p = 0.030). Conclusion: IC dimensions were smaller, MDW of the IF was greater in Brazilian MAE, and the PC was greater in male MAE, highlighting the importance of CBCT in planning, in the absence of maxillary anterior teeth.


The invention relates to identification, screening and variety breeding of crop genetic resources, and particularly relates to an identification method of salt tolerance of barley. The method comprises the steps of preparing a barley nutrient solution, preparing a barley germination substratum, germinating barley and identifying salt tolerance of barley. The method provided by the invention can ensure normal growth of barley during a growth period, avoid influence of environment difference for test results, reduce test errors and drastically improve screening efficiency of barley genetic resources.


The article discusses an original approach that allows the formation of signals based on wavelets by digital synthesis. Its essence lies in the fact that they take the original wavelet and reset its time counts, which have a small amplitude. Then form a spectral representation of the truncated structure and zero the spectral coefficients with a small amplitude. These procedures are repeated until no beats in the spectrum are excluded. Implementation of this approach allows one to obtain signals with new physical properties. In addition, the possibility of synthesizing signals from wavelet fragments has been investigated. It is substantiated that the signal structures obtained on the basis of wavelets have a higher noise immunity, which is achieved by increasing the occupied frequency band. The analysis of the general properties of wavelets is carried out, including the possibility of reconstruction in the time domain from their spectra. The parameters of wavelets that can be modulated by information messages are considered. It is substantiated that the operation of scaling wavelets can be considered as an analog of the frequency for harmonic oscillations. It is shown how it is possible to synthesize manipulated signals with given frequency properties from wavelet fragments. It is shown that when the time periods of the existence of a sinusoid and a wavelet are equal, the spectrum of the latter occupies a much wider band. The results of the analysis of the energy distribution of the spectrum of the sinusoid and wavelet over the duration of their period are presented. An interesting point is considered, when the 15% of the time interval for a wavelet has an energy gain of only 0.7%, while for a harmonic pulse under the same conditions, the gain will be 10%• This fact served as the basis for digital synthesis of wavelets with new properties. The synthesis itself is defined in three stages. First, the initial wavelet is formed in the time domain and the time interval is set, within which no less than 99.3% of its energy is concentrated. Then the amplitude values are zeroed outside the allocated interval. After that, by means of Fourier transform, a frequency representation of a new design is formed, in which all spectral coefficients located outside the main lobe are also zeroed, thus ensuring the smoothness of the function. And at the last stage, the modified structure is again transferred to the time domain.


The Logic of Epistemic Inconsistent (LEI) Pequeno & Buchsbaum 91] is a paraconsistent logic rstly proposed to properly represent a scenario where connicting evidences arise from practical reasoning under incomplete and inaccurate knowledge. In such a situation, it is reasonable to take the attitude of tolerating epistemic contradictions under the same set of knowledge without trivialising it. Although LEI may be suitably used as an underlying logic able to represent situations of multi-agents within Artiicial Intelligence, one of the central topics nowadays, it was proposed as a monotonic basis for the Inconsistent Default Logic (IDL) Pequeno 90]. Therein, plausible conclusions are obtained from default rules based on what is generally assumed and are marked with a pos-xed operator`?' to allow a distinction between plausible and irrevocable knowledge. LEI opens up a series of interesting questions, concerning conceptual and technical aspects, as a paraconsistent formal system. Among the technical issues, we are particularly interested in an analysis of the epistemic paraconsistent negation`:' and of the plausibility operator`?', above mentioned, through a proper characterisation of their deductive power. LEI was rstly presented by an axiomatics. However, aiming to enable an investigation of each LEI operator individually, we will conduct our investigation through a LEI sequent calculus. The cut-free calculus to be presented here will allow us to prove some LEI general properties as the consistency of the calculus, the inversion principle and the subformula property, for instance. This sequent calculus formulation diiers from our previous one ((Martins & Pequeno 94] and Martins & Pequeno 93]) in the way the rules for`?' were deened. With this more concise and elegant formulation, cut proofs are now fully eliminated. The older version kept a controlled case where cut was not ruled out. In fact, if such speciic cut proof were translated to a natural deduction style, a redundancy would not be characterised and those just cited desirable properties, consequences of cut elimination, would still be satissed. Basically, Paraconsistency in LEI is attained, as in da Costa's calculi da Costa 74], by imposing restrictions 1 on reductio ad absurdum axiom. This is reeected in the sequent calculus formulation through the left rule for`:'. Although adequate to achieve paraconsistency, such restriction weakens too much LEI paraconsistent negation. Therefore, some classical theorems, as the double negation and the distribution of`:' over`!', `^' and`_', must be introduced as LEI axioms in order to recover`:' deductive power. It is tacitly …


Plato's position on the knowledge of nature has been the subject of divergent evaluations. Many scholars believe that Plato's influence in this area was disastrous, in that the central hypothesis he defends, that genuine reality is represented by intelligible forms, of which sensible things are mere images, leads more to metaphysics and even to mysticism than to the study of natural phenomena (e.g., Lloyd, 1968, 1991). It may be, however, that Plato's procedure of making mathematics the model of knowledge and describing the stability manifested in the sensible world in mathematical terms, makes him a precursor of modern science (Brisson, 2000). These two contradictory positions can be explained by the very structure of Plato's thought. In this regard, I would like to develop the following three positions:


The article describes the need for multiple passes with disc harrows to increase the degree of grinding of crop residues when preparing the soil for sowing winter cereal crops after row crops. The effectiveness of using additional grinding units for disk harrows is indicated in order to increase the technological efficiency and reliability of the soil preparation process. The analytical dependences are proposed for determining the radius of the grinding unit and the number of bars depending on the structural and technological parameters of the process, biometric parameters of the cut stems and soil hardness, subject to the established cutting value. As an example, a calculation based on the initial data from the reference literature is presented. Based on the obtained dependencies, graphs were constructed, and their analysis was carried out in order to determine ways to increase the efficiency of using the grinding unit. To increase the efficiency of the grinding unit, additional ballast weights and the manufacture of bar fasteners at different distances from the axis of rotation are proposed as technological adjustments.


ICAS recently hosted a live webinar featuring presentations from a group of experts on the Task Force recommendations and the implications for the accounting profession.


The goal of this study is to identify on-line a dynamic model of biodegradation in soil to optimize biological processes by the implementation of advanced control strategies. Namely, the theory of adaptive systems leading to the development of software sensors is investigated to deal with non-measured state variables and unknown parameters involved in the hydrodynamic and biokinetic models. A numerical model capable of describing water flow and biodegradation in porous media is developed and calibrated using laboratory experiments. First, an estimator based on the suction measurement is able to estimate on-line the hydraulic conductivity in steady-state but faces oscillation problems in unsteady-state. Second, using on-line carbon dioxide measurements, an asymptotic observer allows the estimation of hexadecane depletion with a relative error below 5% on the overall time trajectory. This result is significant, as it indicates the potential for real-time monitoring of the performance of treatment bioprocesses in unsaturated soils. Finally, these results demonstrate that the theory of adaptive systems could provide a valuable tool for implementation of advanced control strategies in soil bioremediation processes.


There have been various studies of a propagating beam wave passing through a random inhomogeneous medium and then being reflected back through the same medium.1 The intensity statistics in the far field display an enhancement caused by the double passage through the medium. This enhancement occurs because of single or multiple inhomogeneities, depending on the mirror's position relative to the screen's focus plane. The enhancement has been confirmed in previous theoretical and experimental work. We have developed a computer simulation of this phenomenon, which is known as enhanced backscatter. Although there are many concerns with this phase screen, the assumption made in the simulation is that the phase screen has a power-law spectrum with an 11/3 spectral index. This simulation has been tested with theoretical work2 and has provided a useful tool to study different types of reflectors, along with the general enhanced backscatter configuration.


The existence of multi-resolutions for the perspective-n-point (PnP) problem makes the position-based visual control based on PnP positioning method difficult for practical applications. In this paper, two simple four-point patterns are designed to ensure unique solution for the PnP problem. One is a triangle planar pattern, which consists of three points and their centroid. Another is quadrangle planar pattern. A recursive least square algorithm with a forgetting factor is introduced to improve the solution accuracy. The positioning accuracy based on PnP positioning method is investigated for the two patterns. The method presented in this paper has the advantages of minimum set of known points providing unique solution and linear pose estimation. Experiments are performed to verify the effectiveness of the proposed patterns and method.


Once permitted as a statutory exception to select class of personnel, the amended rules of the Bar Council of India do not permit a person engaged in full time employment to enroll as Advocate and thus practice in India. Recent decisions of the Bombay High Court and the Madras High Court holding that practice in this context implies both litigative practice – i.e. appearance before Courts, tribunals, etc. – as also non-litigative practice – i.e. drafting, providing legal opinions etc. – and their interim affirmation by the Supreme Court, has serious implications on these position. In this paper the author has made an attempt to trace the changes in legal position.The paper examines the legal position under the Advocates Act, 1961 which governs the enrollment and conduct of advocates/lawyers in India, the changes introduced by the Bar Council of India from time to time and recent decisions of the Bombay and Madras High Court relating to practice of foreign law firms in India to examine the currently applicable legal position. Upon appraisal of the various factors affecting the provisions, this paper concludes that Enrollment as Advocate under the provisions of the Advocates Act is essential to carry out litigative or non-litigative practice; and Employees cannot be enrolled as Advocates. Therefore employees cannot carry out either litigative or non-litigative practice.


INTRODUCTION Non-alcoholic fatty liver disease (NAFLD) has been described as the hepatic manifestation of the metabolic syndrome and its prevalence has increased together with obesity and diabetes rates worldwide1,2. Population-based studies describe the prevalence of NAFLD to be between 14-31% in Europe and America3. In Asian-Pacific countries, it been estimated at 9-30%, with higher rates of 10-80% amongst obese patients, 30-90% in patients with diabetes and 15-69% in patients with dyslipidaemia4. NAFLD is a common medical condition, especially among patients who are have the metabolic syndrome, and will frequently present to the family physician. The purpose of this clinical review is to outline an approach to the diagnosis and management of NAFLD in primary care.


The assays that have one of the reactant species immobilized onto a solid support are described as solid phase assays. During the last 20 years a large number of such assays has been developed, the majority of which are quantitative analytical methods known under the general term ELISA (Enzyme Linked ImmunoSorbent Assay). Solid phase assays, in general, have widely been used in Biochemistry, Clinical Chemistry, and Biotechnology, mainly for analytical purposes, and for the detection of specific macromolecules or the study of interactions between various molecules, as well.


Since the end of the 20th century the historical cognition has been enduring essential transforming changes, which occur to the terms the crisis of history, the radical turn inside various challenges. And the investigators pay attention to the plurality of all these processes. According to it the cognitive and structural components of the crisis itself are singled out. It's also called the crisis of growth and the methodological crisis and the crisis of the social function of history. As a result the condition of the science it self is considered by many investigators as a critical one. And the crisis itself become a constant in the history of the historical science. In fact the crisis of the historical science tends to be the crisis of the social institution. It can be overcome only by changing the forms of its institutualisation in the society such a way, that the «producing» of new knowledge about the past will be done in the unity of its formal and pithy features.


School physical education, through its objectives and contents, efficiently valorizes the pupils' abilities, developing them, especially the coordinative skill component, which is the basis of movement learning, of the development of the daily motility and also of the special, refined motility required by the practice of certain sports. Medium school age offers the nervous and motor substratum needed for the acquisition of complex motor habits, a substratum that is essential for the coordinative skill. Individuals differ as to the level at which this function is performed, the extent to which this function turns an individual into a person that is adapted and adaptable to complex and various situations. Spatio-temporal orientation, together with movement combination and coupling, and with kinesthetic, balance, motor reaction, movement transformation and rhythm differentiation form the coordinative skills. From our viewpoint, these are characteristic features with high levels of manifestation in a complex psychomotor act valorizing the quality of one's talent as well as indices pertaining to one's psychomotor intelligence and creativity. Keywords—development, lesson, spatio-temporal orientation, physical education.


There are three accepted methods of recovering storage piles. They are surface reclaiming, sub-grade hopper sections or bins, and flat surface storage with ground level ports. In general, the decision to use either approach is a matter of economics, reliability, labor intensity, and other related practical factors. The concept of induced vertical flow of bulk solids was initiated in 1962 with the birth of the bin activator. Its performance was at times questionable until the elusive cycle type operation was finally discovered. This solved the problems of coupling induced vertical flow units with feeders. Surprisingly, an operator in a cement plant was the first to demonstrate this principle of operation in 1965, but it needed at least five more years for it to be fully understood. The storage pile discharger with its drawdown skirt and unique stroke action was developed out of sheer necessity in 1964. However, it was not until 1979 that the railcar discharger was introduced. Frankly, it took that long to recognize a railcar could be temporarily converted to a huge rectangular shaped activated binexclamation Significantly, all induced vertical flow units are designed and operated for the sole purpose of bulk solid storage withdrawal. They have nomore » other function. For many reasons, the successful evolution of the concept of induced vertical flow of bulk solids has been one of more perspiration than of meditation. Armed with time proven application guidelines and cycle type operation to minimize the effects of feeder flow streams, bin activators, activated bins, storage pile dischargers, and railcar dischargers can be applied confidently and predictably.« less


The modeling of electromagnetic and thermoelectric processes on the basis of numerical realization by finite element method of the generalized three-dimensional models of DC and AC graphitization is proposed. The features of furnace structure and side busbar packages, spatial arrangement of the electrodes blanks in the conductive backfill of core, temperature dependence of the electromagnetic and thermal properties of materials, technological regimes of graphitization are taken into account. The high accuracy and efficiency of numerical implementation are provided. The character and regularities of the spatial distribution of specific thermal power in the core at the vertical and horizontal location of the electrode blanks in the core are defined. It is revealed that the specific electric resistance of the core is determined by the ratio of specific electric resistance of electrode blanks, backfill materials, shunt layers and don't practically depend on the orientation of the electrodes blanks in the Acheson furnace. It is found that in vertical stacking of blanks in the Acheson furnace core at diametric section blanks more heating capacity is allocated compared with the horizontal transverse stacking. Intensification of the heating, reduction in the duration the campaign and energy are provided


In this article the method of formation of methodical competence of students of pedagogical university is developed. The task of the higher school is to raise a new generation of professionally competent mathematics teachers. In this regard, there is a need to develop effective methods of training prospective teachers. The aim of the study is to develop a methodology for the use of mathematical modelling for the formation of methodical competence of the prospective teacher. The study used research methods such as theoretical analysis of scientific literature, observation, generalization. As a result, a method of using mathematical modelling as a means of forming the methodological competence of the prospective teacher was developed. Every method of scientific research, both theoretical and experimental, is based on the method of modelling, since in sign modelling, models appear in the form of graphs, drawings, formulas, systems of equations, sentences in natural or artificial (symbols) language.


Due to the rapid growth of Internet, most of the data that is available in the Internet that is archived/ analyzed, is graph structured in nature as graphs form a powerful modeling tool. The problem of graph pattern matching is to find all the tuples that match a user-given graph pattern from a large directed graph. For faster access of paths in the large directed graph, transitive closure of the graph is compressed and maintained using 2-hop reachability labeling technique by assigning every node a 2-hop label. These 2-hop labels are computed using a geometry-based approach that will be useful in solving the graph pattern matching problem. In this paper, a geometry-based approach that computes the 2-hop reachability labeling is described. The experimental results show that the proposed approach efficiently computes the compressed transitive closure technique of reachability labeling. Keywordsgraph pattern; graph matching; 2-hop cluster; 2-hop labeling; 2-hop cover.


The objective of this report is to investigate how electrical vehicles can be used as taxis and to find a solution that will make the charging process better adapted for the taxi agency. The method used to achieve this is that via user studies and information acquirement through observations and internet create an account for how the taxi business works today and how electrical vehicles is used.The result of this is a fast charging station that can bee placed right next to a waiting area for taxis in a city center. The system is developed to blend in well in an urban environment without being bulky or causing to much attention.The conclusion of this its that any similar solution does not exist today in this form even though this does not implement any new technical solutions. This means that this solution easily could be developed into a finished product and could easily be implemented in cities today. This makes this a solution that is both interesting and topical.


The impact that the theory of automaticity has traditionally had on the explanation of reader development, together with the rise of concern that schoolchildren should acquire greater reading fluency, has caused a proliferation of studies that focus their attention on the speed of the readers. In general, however, these works have forgotten to interpret how reading prosody affects comprehension. The purpose of this paper is to explain how the variables of speed and prosody affect comprehension on a sample of 72 primary school students. A quantitative correlational method is used for this. The results point out that it is the prosody (and not the duration of the reading) what affects the quality of understanding in reading.


Hymenoptera (O'Donnell 1998). In certain Diptera, such as sand flies (Psychodidae: Phlebotominae), the composition of the sugar might affect the development of medically important trypanosomatids (Leishmania) in the gut (Cameron etal. 1995). Polistes eiythrocephalus Latreille (Hymenoptera: Vespidae) was not known to tend or collect honeydew from aetalionids. On March 23, 2004, at 1243h, we observed four aggregations of Aetalion reticulatum (L.) (Hemiptera: Aetalionidae) feeding on a tree, most likely Solanaceae, in Agua Caliente, Department of Cusco, Peru. Each aggregation consisted of approximately 30-40 individuals, including nymphs, and adult males and females. A single female P. eiythrocephalus was standing among or below each of the aggregations of A. reticulatum. Polistes eiythrocephalus touched individuals of A. reticulatum with their antennae but the homopterans did not directly feed the wasps honeydew. Honeydew accumulated below the aggregations of A. reticulatum, and P. eiythrocephalus gleaned the honeydew from the branch directly below the homopteran aggregation (Figure 1 ). Wecollected and tasted the honeydew from the branch to verify that it was honeydew and not rain water. When P. eiythrocephalus was collected, it regurgitated a drop of honeydew from its mouth. This is the first account of P. eiythrocephalus tending A reticulatum and is further evidence that this homopteran is tended by wasps throughout its range. Aetalion reticulatum ranges from Mexico to Brazil and is tended by vespids in Costa Rica (Letourneau and Choe 1987). Voucher specimens of P. eiythrocephalus and A reticulatum are deposited in the American Museum of Natural History (Division of Invertebrate Zoology) and in the Clemson University Arthropod Collection.


Introduction
Aspergillosis of Larynx is very rare and may present with symptoms suspicious of malignancy. Prevention of dissemination warrants early diagnosis. It is found mainly in Immunocompromised patients and is usually necrotizing, invasive with disseminated systemic infection, associated with poor prognosis. In Immunocompetent patients it is extremely rare and may present as colonization associated with excellent prognosis.
Case Report
A 43 year old male patient presented with hoarseness of voice for about 3 months with whitish irregular lesion that involved the anterior 1/3 of both the vocal cords. A cheesy material was found covering indurated lesion of both the vocal cords, intraoperatively. Stripping of mucosa over vocal cords was done and cheesy material collected and sent for HPE which revealed Aspergillus hyphae overlying Mild dysplastic changes. Following diagnosis the patient was followed up with oral dosages of Itraconazole.
Discussion
The primary Aspergillosis of larynx is extremely rare. Involvement is always secondary to immunocompromised states like AIDS, malignancy, Diabetes, etc. This was a rare case in Immunocompetent patient.
Management constitute removal of the vocal cord lesions during biopsy. Amphotericin B is first-line agent for this infection, however aerosolised and liposomal amphotericin B offer effective dosing with less toxicity. Newer antifungal Itraconazole may produce more reliable results.


Starting in 2000, the growth of population and industries sector rapidly increased in Brantas Hulu's river. This phenomenon brought environmental issues since most of industries dispose of their waste including organic-based pollution to the surrounding river. It contaminates the river and lowers the water quality. Minimum assessment on water contamination in Brantas River attracts the research on the area. The study aims to assess water quality on Brantas River based on several parameters: water quality pattern using QUAL2Kw model, determine of pollution level using pollutant index and pollution load capacity. The research relied on a quantitative description by measuring pollution level and calculating acceptable pollution load. The result shows that 10 from 12 sampling areas produced low pollution levels, while the others are moderate level of pollution. The most pollutant found in the Brantas River were BOD, nitrate, ammonia and phosphate. Simulation results from QUAL2Kw model accounted for 10.7% of error rate.


Facial expression recognition is one of the types of non-verbal communication that is not only commons for human but also plays an essential role in everyday lives. The development of science and technology allows the machine to automatically detect human facial expressions based on images and videos. Numerous facial expression detection methods have been proposed in the literature. This paper presents a method to find three basic facial expressions (neutral, happy, and angry) from two parameter values: smile and eyes-open. The analysis involves a preprocessing step using a combination of pre-designed proprietary algorithm and Luxand library. Firstly, the parameters were mapped into two-dimensional space and then grouped into three clusters using K-means, a popular heuristic clustering method. Secondly, more than 50,000 frames for each video were experimented using the proprietary research data. The result shows that the proposed method successfully performed a simple video analysis of facial expressions.


This study was undertaken to evaluate whether exosomes from human adipose‐derived stem cells (ASC‐exo) can stimulate the regeneration of human dermal fibroblasts (HDFs). Immunoblotting and FACS analyses showed that ASC‐exo was positive for exosome markers. Fluorescence tracking revealed that the contents of ASC‐exo were transferred into the HDFs. ASC‐exo treatment also stimulated the proliferation and migration of HDFs in a dose‐dependent manner. Similarly, the expression levels of genes involved in skin cell proliferation were increased by ASC‐exo. Microarray analysis showed an enrichment of microRNAs that have regenerative function. We suggest that the ASC‐exo can stimulate skin cell proliferation.


The utility model provides a two-dimensional sensing structure of capacitive touch control panel, which can save multi-way manufacture processes by a special design of insulating layer pattern. The two-dimensional sensing structure comprises a base-plate, a punctate insulating layer and an electrode layer, wherein a plurality of first metal structures and a plurality of second metal structures are arranged on a first surface of the base-plate; the punctate insulating layer is arranged on the base-plate and comprises a plurality of insulators, each insulator respectively corresponds to each respective first metal structure; the electrode layer is arranged on the punctate insulating layer and consists of a plurality of sensing areas, a first part in the sensing areas are mutually and electrically connected to a first direction by the first metal structures, and a second part in the sensing areas are mutually and electrically connected to a second direction.


Earlier this year, Swedsoft (an industrial network of large Swedish software developers) called for an order of magnitude improvement in software development productivity over the next decade, if Sweden is to remain competitive. Coincidentally, an improvement of roughly an order of magnitude in productivity over conventional programming languages is the claim that has been made for functional programming since the 1980s. In the early days, that claim was based on the brevity of functional programs—the implementation of QuickSort is two lines in Haskell, but twenty lines in Java—and the well-known observation that developers produce approximately the same number of lines of code per day, regardless of programming language. Today, evidence of improved productivity is much more direct.


Current models of the risk of COVID-19 and other airborne infections often are inaccessible to those without a scientific background, rely on assumptions that are not always accurate, and do not provide confidence intervals. This project created a smartphone app design that is able to provide users with a means to determine their risk of infection of airborne diseases with confidence intervals for any room. This was accomplished by using a Dose-Response along with simple and qualitative user inputs (e.g., room geometry, ventilation, number of occupants) to output a probability of infection with confidence intervals.


Held at the University of Bradford, on 1 November 1972, the Immediate Past President of the Society, Mr R. K. Foumess in the chair

A dyeing technologist's view of the development of reactive dyes over the 16 year's of their use, particularly in the package dyeing of sewing threads.


In the scenario of drug discovery, the challenge is to fully understand and elucidate the mechanism of action to identify, with high resolution, the molecular determinant(s) targeted by the drug and responsible for its pharmacological activity. Cancer offers scientists an almost infinite arena of signaling pathways, targets and small molecules for therapeutic intervention. Among the multiple chemotherapeutic strategies to combat cancer, synthetic lethality remains underexplored. Casein kinase 1 ε (CK1ε) is a serine/threonine protein kinase that has been described as a synthetic lethal partner of the Wnt/β -catenin signaling pathway. Despite its potential as a desirable therapeutic target, only two selective inhibitors are available: PF-4800567 and GSD0054. Until the discovery of GSD0054, CK1ε inhibitors have been considered candidate drugs exclusively in psychopharmacology. In this review, we focus on three key points which we consider essential to define the scope of CK1ε as a synthetic lethal partner and its inhibitors as chemotherapeutics: the therapeutic relevance of this kinase, the scarce availability of selective inhibitors (due to the high homology with its sibling isoform CK1δ ), and the constraint of existing computational tools. This paper represents the first review covering the potential of CK1ε as a druggable target for cancer treatment.


By using immunoblotting technique, antigenic structures of various U small nuclear RNPs (UsnRNPs) were analysed which reacted with autoantibodies in sera from patients with collagen diseases. Based on these antigenic structures of UsnRNPs, anti-U1RNP antibodies could be more clearly differentiated from anti-U1U2U4-6RNP [Sm] antibodies. However the reactivity of anti-U1RNP antibodies with each antigenic popypeptides of U1RNP showed marked heterogeneity. An anti- (U1U2) RNP antibody system was newly described with a possible clinical association of the system.Immunoblotting technique was shown to be useful as a sensitive test for screening various anti-ENA antibodies in clinical laboratory. However the sensitivity of the test depended on the concentration of antigens bound to the nitrocellulose membrane.


Global illicit drug addiction has serious negative effects on our society's health, prices of medical care, economy, and level of crime, as well as the environment due to contamination of wastewater, surface waterways, and soil. Therefore, it is crucial that illicit substances can be found in biological fluids and wastewater, as well as in street samples that have been confiscated in order to limit and prevent trafficking and use. By analysing wastewater streams (wastewater-based drug epidemiology), which is one of the key areas of interest for the European Monitoring Centre for Drugs and Drug Addiction, it may also be possible to estimate the total amount of drugs consumed in a certain area [1].


To achieve the stable atmospheric pressure glow discharge(APGD) in air is always a difficult problem,it is easy to converter into arc,and the process is very quick.Based on two electrode structure as needle-needle and needle-plate,MAXWELL 2D was used to analyze the distribution of electric field between electrodes;the breakdown of electric field about nitrogen and oxygen was calculated,and through pulsed power,the conversion time of the discharge was measured.The research shows that the electric field distribution and the maximum electric field are different between two electrodes,and the conversion times are tens of nanoseconds.The needle-plate electrode has the greater maximum field than the needle-needle electrode at the same condition;the conversion times of needle-needle electrode is 25 ns,and the needle-plate electrode are 20 ns.A time parameter was provided to study the basic theory of APGD,and develop the nanosecond pulse power supply.


: Taguchi's T-method belong to the MT System, which is a representative method in quality engineering. Another relevant technique is multiple single regression (MSR), which incorporates the concept of the resistance line. These methods are used to make predictions when there is one output. In addition, multivariate multiple regression analysis is used as a prediction method when there are multivariate outputs. This study proposes methods that apply the T-method and MSR to multiple outputs. The proposed methods are: "independent multivariate T-method" (iMvT), "multivariate T-method" (MvT), "simple multivariate T-method" (MvT+), "independent multivariate multiple single regression" (iMMSR), "multivariate multiple single regression" (MMSR), and "simple multivariate multiple single regression" (MMSR+). iMvT and iMMSR combine predictions simply, MvT and MMSR apply generalized least squares, and MvT+ and MMSR+ apply Moore–Penrose's generalized inverse matrix. We compared the accuracy of the proposed methods with that of multivariate multiple regression analysis. Artificial data analysis was performed by changing the number of training data and correlation. We also performed analyses on the actual data. The results indicate that the proposed methods are more accurate than the existing methods.


The study aims to compare different designs for the World Men's Handball Championships. This event,
organized in every two years, has adopted four hybrid formats consisting of knockout and round-robin stages
in recent decades, including a change of design between the two recent championships in 2017 and 2019. They
are evaluated under two extremal seeding policies with respect to various outcome measures through Monte
Carlo simulations. We find that the ability to give the first four positions to the strongest teams, as well as the
expected quality and outcome uncertainty of the final, is not necessarily a monotonic function of the number
of matches played: the most frugal format is the second best with respect to these outcome measures, making
it a good compromise in an unavoidable trade-off. A possible error is identified in a particular design. The
relative performance of the formats is independent of the seeding rules and the competitive balance of the
teams. The recent reform is demonstrated to have increased the probability of winning for the top teams. Our
results have useful implications for the organizers of hybrid tournaments.


The objective of this study is to evaluate the value of flexibility for cropping system with greenhouse facilities that farmers can take contingent on market condition. A concept of switch option, a kind of Real Options(RO) approach, is adopted to evaluate the option value of flexible cropping system. For the simplicity, region is limited to Chungbuk province and crops for cropping systems are limited to watermelon and melon. Prices of both crops are assumed as stochastic variables and proved to follow mean-reverting process. Results show that farmers choose crops based on relative prices for the first crop. On the other hand, watermelon is hardly chosen for the second crop because the price of watermelon far below than that of melon. The value of flexibility, defined as the difference of the value of flexible cropping system and the value of inflexible cropping system, is 1,583 thousand won during three business years. Sensitivity analysis show that the flexibility value increases with melon production and volatility of melon and decreases with production cost of melon. The results imply that the value of flexibility for cropping system should be reflected in the investment analysis of fruit vegetable farming with greenhouse facilities.


This study described the level of work engagement and areas of worklife of 294 call center agents in Ortigas, Pasig City, Philippines. It also investigated the relationship between work engagement and areas of worklife when grouped according to gender, age, tenure at present job and course. In addition, it also explored the differences in the perception of the call center agents when grouped according to the demographic profile. Gamma correlation was carried out to check if correlation exists between the variables of work engagement and variables of areas of worklife. Mood's median test was conducted to test the differences in the level of engagement and areas of worklife when grouped according to demographic profiles. Results of work engagement showed that those who were aged 31-35 and those who stayed for less than a year in the organization had a high level of dedication. Commerce or Business graduates had a high level of absorption. Results of the areas of worklife showed that majority of the respondents when grouped according to their demographic profile had a match with the variables of fairness, control, values, workload, and community except for the age group of 36 and above who had a mismatch for the variable control. No relationship existed between work engagement and the areas of worklife. Male call center agents are perceived to be more energetic, dedicated and absorbed than female call center agents. Lastly, the areas of control and fairness were reported to differ across all demographic profile of gender, age, tenure at the present job and course.


This work studies the patterns emitted by broad-area VCSELs with a square aperture of 40 /spl mu/ by 40 /spl mu/. The devices are oxide-confined top-emitters lasing at around 780 nm. By controlling the device temperature the above mentioned detuning can be changed and thus the length scales of the patterns. For decreasing temperatures the divergence angle of the emission (the transverse wave number) increases and fewer modes are selected resulting in a less complex pattern. This paper studies these relationships quantitatively and considers how to extract the value of the detuning experimentally. In the theory, phase lag in the spacer layer as well as the one in the Bragg reflector is taken into account. Additionally, this study looks into the polarization properties of the emission.


A finite element model of coach body structure was established based on ECE R66 regulations, and verified through comparisons of front and rear axle load distribution ratio, deformation and modal frequency of simulation and experimental results. After the set up of coach-highway slope collision system, rollover of coach body was carried out by simulation methods, and the movement posture of coach in rolling and intrusion amount of survival space were obtained. The results show that the large deformation of the upper part of coach body is mainly due to plastic crushing of side wall pillars and roof joints; the slope height and gradient have a significant influence on the roll posture, deformation and intrusion amount of occupant's survival space; the occupant's survival space has been invaded, therefore, the coach body structure does not meet the rollover safety requirements.


Both U.S. and world economies have long depended on fossil energy (coal, oil, and natural gas). Supplies of fossil energy are expected to decline in the future and become more expensive. Meanwhile, their use contributes to the accumulation of greenhouse gas in the atmosphere. Therefore, an urgent need exists for renewable energy sources. In order to enhance the global competitiveness of the U.S. in renewable energy manufacturing, there is a dramatic need for a skilled workforce that has been trained in this field. A survey on renewable energy courses at more than 100 U.S. universities has been conducted. It is found that manufacturing aspects of all forms of renewable energy are not emphasized, and there are no sophomore-level courses that cover manufacturing of all forms of renewable energy at these universities.Copyright © 2011 by ASME


OBJECTIVE To observe the effects of chloroprocaine used in clinical epidural analgesia for the elder who had accepted transurethral resection of the prostate(TURP).METHODS Eighty patients of 60-75-year-old were enrolled in the randomized and double-blind study.They were divided into A,B,C and D four groups(n=20).All patients accepted L3-4 3% chloroprocaine epidural anesthesia.After they were undergo TURP,the patients remained the epidural catheter for continuous epidural chloroprocaine hydrochloride analgesia for 3 days according to different doses: A group: 0.9% NS;B group: 1% chloroprocaine;C group: 1.2% chloroprocaine and D group: 1.5% chloroprocaine.We monitored the blurred vision score(VAS score),modified Bromage score,the number of bladder spasms,respiratory and circulatory changes,central nervous system reactions,and degree of satisfaction for all the patients.RESULTS For the VAS score and frequency of bladder spasm,the means of A group were less than those in B,C,and D group with significant statistics difference(P0.01),the means of B group was less than those in C and D groups,but no statistical difference.Though C and D groups had no difference in VAS score,but the number of bladder spasm of D group was less than C group.The Bromage score of four groups were 0 in postoperation-6h.Nearly 11 patients in A group had low satisfaction and could not tolerate,most patients with continuous epidural chloroprocaine hydrochloride analgesia had satisfied with the analgesic effect.All patients had no respiratory and circulatory changes and the adverse reaction in the central nervous system.CONCLUSION The chloroprocaine used in epidural analgesia after TURP for the elder had good analgesia effect and safty.


German departments in the United Kingdom often still have a traditional canon when it comes to their pre-twentieth century syllabus. This came into being when the history of German literature was established at the end of the eighteenth and the beginning of the nineteenth centuries. This 'official' German literature excluded women writers, even though in this period there was a great number of them, for reasons which the article discusses. The article then attempts to demonstrate what is lost if female voices are excluded from the canon. Attempts to extend it are, however, usually countered either by assumptions that women's writing must be of lesser quality than men's, simply because it is not canonical, or by assump tions that, because German literature is full of depictions of women, women's experience is thereby taken into account. The article questions these two responses and then goes on to posit that feminism will not only change and expand what students of German read but must also profoundly alter how canonical works and authors are taught. Ultimately, this will lead to a questioning of all working practices within academic institutions.


Abstract This article is about some of the governmental experiences of the jurist/diplomat/minister M.C. Chagla, through which, it seeks to cast a certain light on the possibilities and limits of relations between a majority state and a minority individual, albeit of the privileged kind. Chagla's pre-eminent presence in Bombay's legal fraternity from 1922 and the High Court from 1941 bequeathed to him a sense of belonginess, which was largely untouched by the upheavals of 1947. His 11 years as Chief Justice, followed by five years as India's envoy in U.S./U.K., saw him being elevated to the central cabinet, but not without a question mark at his non-party and non-majority identity. His short ministerial stint till 1967 ended over two issues of identity politics—a domestic language policy and an international crisis—providing a prism to see the coming together of competence, concerns and convictions around cooperation across parties, classes and communities.


To review relevant national and international research in order to classify animal models of intraocular hypertension into acute and chronic types. The establishment and characteristics of the models are discussed. Anterior chamber irrigation and methylcelulose induction were considered to be the most effective methods in establishing acute and chronic intraocular hypertension models. [FK(WB80011?6]


Objective To investigated the effect of study on establishment of diabetic neurogenic bladder of rat model induced by streptozotocin. Method Male Sprague-Dawley(SD)rats of eight-week-old were randomly assigned into normal control group(group NC) and diabetic mellitus group(group DM). Diabetic rat was established by single intrapertoneal injection of 2% streptozotocin. The body weight was examined in 1, 2, 3, 5 and 8 weeks. The volume diet and water intake were analyzed in 3, 5 and 8 weeks. blood glucose was examined in 1 and 8 weeks. The residual urine volume and bladder weight were obtained in all subject at 8thweek. Bladder tissues were studied histologically after the experiment using light microscope. Results Compared with group NC, significantly elevated blood glucose, bladder weight were revealed in group DM(P 0.05). Also significantly increased volume diet, water intake and residual urine volume were revealed in group DM(P0.05). Furthermore, derangement, loosed structure and muscle bundle rupture were observed in detrusor muscle of diabetic rats. Conclusion The method of streptozotocin including diabetic neurogenic bladder of rat model is simple, reliable and stable.


One of the ideas behind vegetation monitoring is the ability to identify different vegetation units, such as species, communities, habitats, or vegetation types. Remote sensing data allow for obtaining such information remotely, which is especially valuable in areas that are difficult to explore (such as mountains or wetlands). At the same time, such techniques allow for limiting field research, which is particularly important in this context. Remote sensing has been utilized for vegetation inventories for many decades, using airborne and spaceborne platforms. Developing newer tools, algorithms and sensors is conducive to more new applications in the vegetation identification field. The Special Issue "Remote Sensing Applications in Vegetation Classification" is an overview of the applications of remote sensing data with different resolutions for the identification of vegetation at different levels of detail. In 14 research papers, the most frequent different types of crops were analysed. In three cases, the authors recognised different types of grasslands, whereas trees were the object of the studies in two papers. The most commonly used sensors were Copernicus Sentinel-1 and Sentinel-2; however, to a lesser extent, MODIS, airborne hyperspectral and multispectral data, as well as LiDAR products, were also utilised. There were articles that tested and compared different combinations of datasets, different terms of data acquisition, or different classifiers in order to achieve the highest classification accuracy. These accuracies were assessed quite satisfactorily in each publication; the overall accuracy (OA) for the best result varied from 72% to 98%. In all of the research papers, at least one of the two commonly used machine learning algorithms, random forest (RF) and support vector machines (SVM), was applied. Additionally, one paper presented software ARTMO's machine-learning classification algorithms toolbox, which allows for the testing of 13 different classifiers. The studies published in this Special Issue can be used by the vegetation research teams and practitioners to conduct deeper analysis via the utilization of the proposed solutions.


An impact assessment of the beneficiaries of 'e-Velanmai' was undertaken in Palar sub-basin district of Tamil Nadu. Palar sub-basin consists of 3 Water user Associations (WUA). About 20 respondents were drawn randomly from each WUA making the total sample size to 60 beneficiaries of 'e-Velanmai' project. Partial budgeting technique was used to assess the impact of e-Velanmai. The study compared conventional approach of extension with e-Velanmai approach on various dimensions. The study also explored and presented the strengths, weaknesses, opportunities and challenges (SWOC) of the ICT enabled extension model. Findings from the research showed that e-Velanmai has positively impacted farmers and improved their income. The comparative analysis shows that e-Velanmai is comparatively effective method of extension approach in various aspects.


In a recent issue of thisJournal, Mohabbat and Simos (1978) provided estimates of the rate of discount using Kendrick's (1976) series of total private wealth. Since Kendrick also provides estimates of the division of total wealth between human, Wh, and nonhuman, W,, wealth, it should be of interest to investigate how the discount rates differ between the two components of wealth. In order to accomplish this, it is necessary to divide the total income into two parts-one corresponding to the human wealth, Yh, and the other to the nonhuman wealth, Yn. Kendrick (1976, p. 22) and Christensen and Jorgenson (1973) provide an outline of the method for such a division of the total income. Following them, the time series for Y'h and Y1, were estimated. The estimated series closely approximate the estimates for "labor compensation" and "property compensation" given by Kendrick and Christensen and Jorgenson. As suggested in Mohabbat and Simos, the time-series estimates of the rate of discount for Wh and Wn were computed using the varying parameter regression technique. These series are given in table 1. The obvious inference that can be drawn from the results given in table 1 is that the discount rate on Wh is consistently higher than the rate on Wt. This evidence is important by itself. In the absence of direct empirical estimates, as provided here, economists had to make assumptions about the behavior of the two rates (see Pesek and Saving 1967). Additionally, since the major portion of WI, is education, the results provide further evidence on what Welch has called "one of the most important phenomena of our time . . . that the rates of return to investments in schooling have failed to decline under the pressure of rapidly rising average educational levels" (Welch 1970, p. 54). The existence of a relatively higher rate on Wh confirms the conclusions about the behavior of the rate of return on education arrived at by Griliches (1970, 1977), Welch (1970), Becker (1975), and others.


: This article takes A-share listed companies in the Shanghai and Shenzhen stock markets of China from 2006 to 2021 as research samples to evaluate the impact of total factor productivity on real earnings management of enterprises. The research has found that: (1) Improving total factor productivity in enterprises will reduce real earnings management of enterprises. (2) Mechanism analysis shows that an increase in total factor productivity of enterprises will lead to an increase in revenue growth rate, thereby inhibiting the real earnings management of enterprises. The conclusion of this article indicates that in good operating conditions, companies will reduce real earnings management of enterprises.


BACKGROUND
Previous studies have shown that latex proteins from Plumeria pudica (LPPp) have anti-inflammatory and antioxidant activity. Therefore, the aim of this study was to evaluate the effects in rats of LPPp on ligature-induced periodontitis, an inflammatory disease.

METHODS
The animals were divided into groups: saline (animals without induction of periodontitis); periodontitis (induced periodontitis and untreated) and LPPp (induced periodontitis and treated with 40 mg/kg). The following parameters were evaluated after 20 consecutive days of treatment: gingival bleeding index (GBI), probing pocket depth (PPD), alveolar bone height (ABH) and gingival myeloperoxidase (MPO) activity. In the hepatic tissue, malondialdehyde (MDA), glutathione (GSH) and histopathological alterations were evaluated. Blood levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured.

RESULTS
Significant reduction of GBI, PPD and gingival MPO activity and ABH was seen in animals treated with LPPp compared to periodontitis. Values of GSH, MDA, ALT and histopathological evaluation were preserved in animals treated with LPPp.

CONCLUSIONS
Treatment with LPPp improved clinical aspects of periodontitis, reduced the blood and hepatic alterations and prevented alveolar bone loss. Data suggest that LPPp have potential for treatment of periodontitis.


If, in a figurative sense, a writer is either a hedgehog who knows one big thing or a fox who knows many things, Professor Mitchell certainly displays fox-like characteristics. Upward o'f thirty years' involvement in the Caribbean, together with wide reading, enables him to discourse intelligently on a variety of topics. One may learn about Castro's Cuba, Duvalier's Haiti, Trujillo's Dominican Republic, Munoz's Puerto Rico, Williams' Trinidad, Jagan's British Guiana, Bustamante's Jamaica, not to mention such small islands as St. Croix, Martinique, Barbados, Curacao, and Grand Bahama. For each of these and other territories there are short historical introductions followed by fuller treatment of contemporary politics and economics. Given the patchwork nature of the Caribbean, one may understand the author's interest in unique and particular aspects of a region that has been and remains a storm center of nature and man alike. But the test of a good book is its ability to relate the unique and particular to the uniform and general, and for this purpose one needs a hypothesis, or a tentative theory which is provisionally adopted to explain certain facts and to guide in the investigation of others. Unfortunately, the lack of a hypothesis in the book under review leads to a patchwork view of the Caribbean on the one hand, and rather superficial and ambiguous generalizations on the other* The chapters on agriculture arid economic development illustrate some of the weaknesses in the generalizing section of the book. Most of the Caribbean territories are plagued with limited supplies of good agricultural land, rapidly growing populations, migration from farm to cities, and high levels of unemployment and underemployment. Alternative proposals to alleviate these problems by either continuing the sugar export pattern or encouraging crop diversification and land reform are considered but not analyzed in much depth. While the author realizes the limitations of the Puerto Rican model of industrial development for the small territories in the Caribbean, one may question his qualified enthusiasm for tourism as a builder of viable economies. Dependence on external capital to diversify old rnonocrop economies may be unavoidable. But diversification and industrialization may be purchased at so high a price that the search for an alternative strategy of development must continue.


In the early half of 1922 a boring ("jumped") was made by Mr. H. G. Godwin, of Quenington, Fairford, Gloucestershire, for Mr. Oswald Collier, of Calcutt, in search of water. The site of the borehole is at Calcutt—¼ in. above the "C" in Calcutt on 6 in. map, 5 S.W., Wilts.


Despite relating to so-called 'second-order' elections, by contrast to 'Ž rst-order' parliamentary and/or, where applicable, presidentia l elections, these books make important contributions to understanding contemporary Italian politics. As studies of political opportunity structures have shown, subnational and European elections can be important access points for new political actors and hence are important for their role in party system and political change. Over the last decade, of course, electoral outcomes in Italy have been transformed, albeit there is a school of thought that electoral behaviour has changed remarkably little. At any event, in this period at least, local elections have mattered for more than just local politics. The interplay of local and national politics has been, and remains, highly signiŽ cant and Baldini and Legnante identify several examples of this: the upsurge of the Lega Nord which became unstoppable from December 1992, and the rise of Alleanza Nazionale in 1993 which demonstrated—to those who wanted to see—that it could not be ignored in planning for future parliamentary elections; the experimentation of 1995 that led to the formation of the Ulivo centre-left alliance; Cossiga's mistaken interpretation of the 1997 results such that he believed he could restructure Italian politics, marginalizing both Rifondazione Comunista and Alleanza Nazionale; the formation of the Democratici in 1999 in which the mayors' movement Centocittà played a major part (albeit another (European) second-level election was crucial); the 2001 elections in which the mayor of Rome, Francesco Rutelli, was but the most prominent of many mayors who were forced to stand down after reaching the two-term limit and who moved into national politics. The Ž rst of these volumes, Città al voto, is typical of the ecologically based electoral studies published by Il Mulino. Clearly written, analytically thorough,


Higher Education is undergoing continuous changes in the process of Globalization as it brings rapid development in the technology and communication skills through changes in the learning system across the world. Higher Education is a vital sector for economic growth and development of a nation. The report of the Education Commission (1964-66) under the chairmanship of Dr. D.S. Kothari symbolized the symbiotic relationship between education and national development. The capitalist economy strongly focused in free trade, "Due to this increasing free trade around the Globe, that end protection of many sectors so that there is more competition and privatization of education is increasingly being drawn into this Global capitalist competition. A study done by Dr. Pulkit Agarwal, Miss. Taiba Ahmad and Miss. Dalgindar Kaur, has analyzed that India has a low rate of enrolment in Higher Education at only 18% compared with 26% in China and 36% in Brazil. There is enormous unmet demand and supply gap for Higher Education. By 2020 the Government aims to achieve 30% gross enrolment which will mean providing 40 million University places an increase of 14 million in six years. India is currently at the stage of demographic transition population. Government of India aimed to increase 25.2% by 2017-18 and reach the target of 30% by GER 2020-21. To achieve this, the enrolments need to be substantially revised in Universities / Colleges to reach the target by 2017-18. The paper will concentrate on the analysis of this matter.


timeliness of Financial Statements is the audit report lag. Audit report lag is also affected by many factors and one of these factors is adopting corporate governance principles. Corporate governance consists of several principles that provide less arbitrary and transparent organization management regarding to rules and law and form a powerful control and review system. From this point of view, this study investigates the relationship between audit report lag and corporate governance level of companies that are not liable to prepare consolidated financial statements and listed on Istanbul Stock Exchange between years 2006-2011. Also this study analyzes the effects of factors that mentioned in literature on audit report lag. Results of this study show that "to be listed in Corporate Governance Index" relates negatively with audit report lag. "Number of segment reporting" and "listed in Industrial Index" also reduce audit report lag. On the other hand, it's revealed that "high number of subsidiaries" and "auditing by big four auditing firm" increase audit report lag.


VIDEO DESCRIPTION: Our technique for large paraoesophageal hernia repair and gastropexy shown step by step. This approach takes components of a series of historical anti-reflux operations and can be seen as a hybrid of Hill, Toupet and Nissen with anterior and posterior hiatus repair.
 1. Sac approached infero-posteriorly on the right crus after phreno-esophageal ligament identified and separated at the V.
 2. Sac separated from the pleura in the mediastinum.
 3. Sac dissected from right to left along the edge of the hiatus.
 4. Short gastric taken, posterior component of the sac dissected.
 5. Sac reduced and completely excised.
 6. OGJ identified.
 7. Hiatus repair: posterior and (mainly) anterior.
 8. Mobilised fundus slid behind the oesophagus.
 9. Angle of His reconstituted.
 10. Lateral and posterior fundo-pexy (Toupet).
 11. Mediastinal drain.
 SEE DESCRIPTION: Esophago-Gastric Junction-plasty with anterior and posterior hiatal repair is an anatomical anti-reflux procedure which can be performed for large paraoesophageal hernias.


Distributed storage systems with replication are well known for storing large amount of data. A large number of replication is done in order to provide reliability. This makes the system expensive. Various methods have been proposed over time to reduce the degree of replication and yet provide same level of reliability. One recently suggested scheme is of Regenerating codes, where a file is divided in to parts which are then processed by a coding mechanism to provide large number of parts. These are stored at various nodes with more than one part at each node. These codes can generate whole file and can repair a failed node by contacting some out of total existing nodes. This property ensures reliability in case of node failure and uses clever replication. This also optimizes bandwidth usage. In a practical scenario, the original file will be read and updated many times. With every update, we will have to update the data stored at many nodes. Handling multiple requests at the same time will bring a lot of complexity. Reading and writing or multiple writing on the same data at the same time should also be prevented. In this paper, we propose an algorithm that manages and executes all the requests from the users which may reduces the update complexity.We also try to keep an adequate amount of availability at the same time. We use a voting based mechanism and form read, write and repair quorums.


For the study of the economic development of modern China the scholars have different views from different angles.This paper attempts to study from the perspective of the role of government management and institutional change.We find that in modern China's economic development,macro-formal institutions and informal institutional change,and the government has played a huge role in economic growth,but also caused confusion in the economic development.of modern China.


A centralized computer system is provided to operate and manage a computer main unit in a state separating computer peripherals like a monitor, a keyboard, or a speaker from the computer main unit over a predetermined distance to integrally manage a plurality of computers installed in an office, an Internet cafe, or a school. A computer main unit(100) includes a main board(110), and a main connection port(120) for controlling a computer peripheral(400) or receiving a signal from the computer peripheral. The main connection port and a first transceiver(200) input/output the signal through a first cable(500). The first transceiver and a second transceiver(300) are separated in a distance, and input/output the signal through a second cable(600). The second transceiver comprises a case, a second control PCB(Printed Circuit Board) processing the signal in the case, a third interface inputting/outputting the signal to a second control PCB by connecting to the second cable, a slave connection port inputting/outputting the signal of the second control PCB by connecting to a cable of the computer peripheral, power and reset switches for operating the computer main unit, and an LED(Light Emitting Diode) for checking an operation state of the computer main unit.


Introduction: Infections caused by Acinetobacter species have now been becoming troublesome due to their ability to develop resistance. Current study was aimed and to find microbiological cut-off of Elores against Acinetobacter species. Material and Methods: In this study, 457 clinical isolates of Acinetobacter species recovered from patients were involved. Breakpoint of Elores was established using the methods of pharmacokinetic and pharmacodynamic correlation. Results: Among 457 isolates, 26.9% were ESBL (Extended Spectrum Beta-Lactamases) positive, 51.2% were MBL (Metallo Beta-Lactamases) positive and remaining 21.8% isolates were ceftriaxone susceptible. Out of identified ESBL and MBL producers 20 strains (10 ESBL and 10 MBL) were picked randomly for gene characterization and it was observed that 3 were TEM-1 positive, 1 was SHV-1 positive, 1 was AMP-C positive, 2 were OXA-1 positive, 3 was CTX-M positive, 3 were VIM-1 positive, 4 were IMP-1 positive, 3 were NDM-1 positive. In ceftriaxone, resistant Acinetobacter group, the MIC50 and MIC90 for ceftriaxone were 16 and 128 μg/ml and for Elores MIC50 and MIC90 were 4 and 8 μg/ml, respectively. The MIC cut off for Elores against ceftriaxone resistant Acinetobacter species was ≤8 μg/ml. Similarly, the AST cut off for Elores against ceftriaxone susceptible Acinetobacter species was ≥21 mm. The AST and MIC cut off for Elores against ceftriaxone resistant was same as of ceftriaxone susceptible. Conclusion: Our data apparently indicates that Elores could be a better option to curb ESBL and MBL producing pathogens which synergistically provides clinically relevant concentration at higher susceptible MIC values.


The paper discusses the problem of rotor position estimation for the nonsalient permanent magnet synchronous motor (PMSM) and presents a Sliding Mode (SM) EMF observer that is based on the machine's model in the stationary reference frame. The speed of the PMSM which is an input of the proposed sliding mode observer is obtained from a speed estimator. The paper assumes that the speed estimate is different from the real speed and shows that the gains of the SM observer can be designed such that the EMF estimates produced by the SM observer tend to the real EMFs. The observer is designed and analyzed in the framework of nonlinear control using Lyapunov's theory and is validated using simulations. The method proposed is relatively simple and can be used to estimate the rotor position of the PMSM in a sensorless drive.


Polygonum papillosum, a woody species of Polygonum sect. Polygonum from serpentine soils in Central Greece, is described as a species new to science and illustrated. It is related to the Anatolian P. setosum, but differs in leaves with very dense and prominent, papillose veins, strongly splitting ochreas and numerous elongated vegetative shoots


A pulsed HF chemical laser utilizing the chain reaction between H2 and F2 has been operated with electric discharge initiation. A uniform transverse discharge is made possible through the use of spark preionization. For the mixture 1:1:10:0.06 (F2:H2:He:O2) at 120 Torr total pressure an output energy 1.01 times the electrical input has been achieved. The corresponding chemical efficiency was ∼1.0%. A tradeoff is observed between electrical efficiency and chemical efficiency with the maximum chemical efficiency of 2% being achieved at an electrical efficiency of 25%. Even higher electrical efficiencies are expected with further device optimization.


In a withering critique of statistical praxis, Gary King (1986) has recently warned modelers off standardized regression coefficients, bivariate correlations, and coefficients of determination (R2s). Without denying that these particular statistics are frequently abused (and without taking issue with any of King's other admonitions), I want to argue here that they are not therefore useless-and, in the process, to sketch their legitimate uses.


This report primarily pertains to the non-destructive13; evaluation of candidate CFRP components chosen for the demonstration of various repair schemes . Nondestructive13; evaluation involved through transmission C-scan inspection . The purpose here was two-fold : to map the extent of damage and to assess the efficacy of the repair scheme . A few destructive tests were also performed in the case of bonded scarf repair of CFRP laminates for assessing the repair scheme


In this paper, we study a class of naturally ordered abundant semigroups with an adequate monoid transversal, namely, naturally ordered concordant semigroups with an adequate monoid transversal. After giving some properties of such semigroups, we obtain a structure theorem for naturally ordered concordant semigroups with an adequate monoid transversal.


In this article we examine the notion of 'harmonisation' in its interplay with the application of provisions on the free movement of goods. Due to the introduction of the European unitary patent protection system, we are witnessing the first cases of adopting enhanced cooperation in the internal market. This fact raises new, systemic questions concerning the concept of 'harmonisation' in European Union law. Are only legal, substantive aspects covered by its definition or should the territorial range of a legal act be taken into account? If yes – to what extent? Since the adoption of enhanced cooperation covers the field of intellectual property rights, the above questions concern the relationship between exercising those rights on the one hand and the principle of free movement on the other. A closer look at this matter leads to the conclusion that the unitary patent might not provide the solution to one of the problems that created for. More generally, in this article we conclude that when defining the concept of 'harmonisation', one should take its territorial scope into account narrowly, so as not to infringe the principles of EU law.


Instead of stiched simple catenary, heavy simple catenary and diamond type simple catenary were newly developed to improve anti-wind performance. Contact loss, uplift and anti-wind characteristics were tested, and these catenaries showed satisfactory results.


The provision of data with information management are a significant challenge for the digital developing construction industry. The utilisation of data from a built asset's planning, design, and construction phases to the operations phase core and to the facility management function of building and integration in supporting core business and support services is frequently limited due to technical obstacles in information management. The paper presents the second of three stages of design science research to propose a conceptual approach for the implementation of the "as-a-service" method for the construction industry, namely "Building-as-a-Service" (BaaS). BaaS involves a shift in the concept of services: users become recipients of services generated by the building, not only services provided in the building. The paper shows the interdependencies between these various concepts and suggests a possible framework for the inclusion of these "as-a-Service" approaches for enabling a Digital Twin based on Building Information Modelling, which is becoming mandatory in several European states. The study gathered the foundational theoretical constructs through a literature review and elucidated them to make the proposed framework feasible. The theoretical foundations comprise Building Information Modelling (BIM), the Digital Twin (DT), the interconnecting technology of smart applications and the practical application in projects. The approach of "Building-as-a-Service" in combination with smart applications can be an approach to making the use of buildings available in a resource-saving way to clients, building owners and users.


Antituberculosis drugs (ATD) used as standard drugs for the treatment of deadly disease tuberculosis, cause blood disorders. The present study was conducted to investigate the efficacy of propolis against ATD induced alteration in blood parameters in rats. Rats were administered with ATD for 8 weeks (3 days/week) followed by propolis at three different doses (100, 200 and 400 mg/kg) conjointly for 8 weeks (3 days/week) orally. Silymarin (50 mg/kg) was used as positive control in the study. After 8 weeks, animals were euthanized; blood was collected by retro-orbital sinus method for analysis of hematological parameters. The results of this study show a decrease in red blood cells, hemoglobin, hematocrit, mean corpuscular volume, red blood cell distribution width alongwith increase in the number of lymphocytes in ATD induced rats. Treatment with propolis extract encountered ATD induced blood parameter alteration which was evident by significant reversal in hematological indices towards control in a dose dependent manner. Thus, it can be concluded that propolis may be an agent of therapeutic choice in case of ATD induced hematological alterations.


Any possible visitors to the exoplanet, called Kepler-13Ab, would need to bottle up some of that sunscreen from the nighttime side, because they won't find it on the sizzling hot, daytime side.


Within a large space of tests, many variables may have the same settings. AI researchers report that when solutions share settings, then solutions can be found, faster, by rst nding and setting just a few of the shared variablesa phenomenon they call "backdoors". This paper shows that backdoors can dramatically improve test case generation. If backdoors exist, then they exist in most solutions. Hence, test suites can be quickly generated just by sampling around average values seen in a few randomly selected valid tests (as done by our new algorithm called S). When applied to 27 real-world test case studies S ran 10 to 3000 times faster (median to max) than a prior report (at ICSE'18). While prior work found tests that were 70% valid, all S's tests were valid Test engineers would nd it easier to use S's tests since those test suites are 10 to 750 times smaller (median to max) than those found by prior work.


It is discussed the LQR semi-active control algorithms and calculation model of seismic response in the elevated highway bridge under the logitudinal forces,and numerical simulative calculation is carried out by Matlab program.The results of the calculation show that it is effective to reduce seismic response of the elevated highway bridge by combining vibration insulation with semi-active control technique under the earthquake.The location of MR damper and structural parameters have great influence on the effects of structural control.


Fluorine-terminated chemical bonds and dipole structures within an Al2O3 layer were investigated in this study. Spectroscopic ellipsometry (SE) was employed to estimate the characteristics of fluorinated Al2O3. The parameters S0 and λ0 extracted from SE were analyzed to detect the influence of F-terminated bonding. Al–O bonds were replaced by the Al–F bonds after fluorine was implanted on the silicon substrate. A physical model of dipole structures was proposed explaining the F incorporation phenomenon.


LONGITUDINAL PREDICTORS OF QUALITY OF LIFE IN ADOLESCENT SURVIVORS OF CHILDHOOD CANCER: A REPORT FROM THE CHILDHOOD CANCER SURVIVOR STUDY By Claire C. Russell, M.S. A Dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University, 2013 Major Director: Marilyn Stern Professor, Department of Psychology Objective: The impact of childhood cancer on future quality of life (QoL) in survivors is unclear. Current studies focus on comparing outcomes to healthy peers and identifying related treatment and demographic variables, but a shift in our approach is necessary. This study is guided by the Wilson and Cleary Model (WMC) and seeks to identify longitudinal predictors of QoL in adolescent survivors of cancer that explain variance in QoL beyond the impact of treatment and demographic variables. Methods: The Childhood Cancer Survivor Study (CCSS) is a multiinstitutional longitudinal study following a cohort of childhood cancer survivors. This study focuses on the CCSS cohort (N = 305) who completed the baseline survey in 1994 and the Teen survey in 2001. The baseline survey assessed parent-report of child's psychological and physical symptoms, functional status, and health perceptions. The Teen survey utilized the Child Health and Illness Profile – Adolescent Edition (CHIP-AE), a self-report measure assessing QoL in six domains: achievement, resilience, satisfaction, discomfort, disorders, and risk. The primary hypothesis was that psychological and physical symptoms, functional status impairment, and health perceptions as rated by parents at baseline would predict variance in quality of life as rated by adolescents at follow-up after adjusting for demographic and treatment-related variables. Six separate hierarchical regressions were analyzed for each of the QoL domains. Results: The main hypothesis was supported. For each QoL outcome, a significant amount of variance was predicted: achievement, F (6, 259) = 8.90, p < .001, adjusted R 2 = .152, resilience, F (12, 209) = 3.47, p < .001, adjusted R 2 = .118, satisfaction, F (6, 265) = 8.73, p < .001, adjusted R 2 = .146, discomfort, F (7, 273) = 6.75, p < .001, adjusted R 2 = .126, disorders, F (9, 212) = 6.47, p < .0001, adjusted R 2 = .182, and risk, F (7, 238) = 4.81, p < .001, adjusted R 2 = .098. Furthermore, for all outcomes, psychological and physical symptoms, functional status impairment, and health perceptions predicted variance above and beyond the impact of demographic and treatment variables. These factors accounted for an additional 9.5% of the variance in the achievement domain, 6.2% for resilience, 10.8% for satisfaction, 6.5% for discomfort, 12.4% for disorders, and 6.1% for risk. Conclusions: Results suggest that psychological and physical symptoms, functional status and health perceptions should be assessed and targeted in interventions for childhood cancer survivors to promote future positive QoL. Future studies need to continue identifying factors related to positive long-term functioning in diverse samples of childhood cancer survivors.


OBJECTIVE
The role of p53 mutation in renal cell carcinoma (RCC) is not fully understood particularly among Japanese, although frequent loss of heterozygosity (LOH) has been demonstrated at polymorphic exon 4.

METHODS
We examined the p53 gene in 43 primary RCC samples by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) analysis for exons 4-9 and restriction fragment length polymorphism (RFLP) analysis.

RESULTS
In PCR-SSCP analysis, no apparent mobility shift was observed regardless of the clinical stage of the disease, histological subtype or malignancy grade of the tumor. In RFLP analysis, none of 13 informative cases showed gross alteration of the gene.

CONCLUSION
We conclude that mutations of the p53 gene are not major events in the development and progression of RCC among Japanese.


A 219 MHz, β = 0.303 superconducting triple-spoke cavity has been designed to be used as a rebuncher for intense uranium beams at RIKEN RI-Beam Factory. Shapes and positions of spokes has been optimized reducing peak surface electric field and a diameter of the cavity. For the purpose to establish a fabrication method, and to check accuracy of calculation, a single-spoke copper model is planned to be constructed.