Performance of two inter se mated Brahman (B)-Angus (A) crossbred populations, 3/8B:5/8A (Brangus) and 1/2B: 1/2A (BxA), was compared at the Everglades Research and Education Center, Belle Glade, FL. Data covered six mating seasons and included 751 cow and 611 calf records. During a 70-day breeding season Brangus cows were bred to Brangus bulls and BxA F1 and F2 cows were bred to BxA F1 bulls. All herds grazed year-round on Roselawn St. Augustinegrass pastures grown on organic soils, at a stocking rate of 1.25 cow units per acre. The infer se mated BxA had a higher cow productivity performance (P<.03) and tended to have a greater cow efficiency value (P < .13) than the inter se mated Brangus. Most of the greater productivity of the BxA over the Brangus was the result of higher pregnancy rate (86.9 vs 81.2%) and a lower prenatal mortality (1.6 vs 5.3%), which resulted in a significantly higher weaning rate in the BxA (78.6%) than in the Brangus (71.2%). Comparisons among the BxA F1, BxA F2 and Brangus showed that the BxA F1 cows were superior in productivity than the two other groups. Little difference existed between the Brangus and BxA F2 cows for cow production parameters.


The protection function of flameproof switch is designed to voice promt by using digital signal conversion IC,digital storage,sound production touch and double power amplifier so as to warn the operator elimate safe problem accuratly and in time.


In an effort to identify a situated strategy for enhancement of the Valle Vitulanese, an inner marginal area of the province of Benevento (Italy), the paper structures an evaluative methodological approach that recognizes and interprets the valley as a multifunctional cultural landscape. The outcome is an enhancement strategy that leverages the specificity of each municipality to enable local networks to activate dialogue between recovery and development of tangible and intangible resources. The first territorial action develops in the old town of Tocco Caudio, one of the eight municipalities of the valley, investing on the valorisation of local resources and triggering an incremental process of revitalization, able to strengthen the system of values and relationships which characterizes the context of vast area whose Tocco Caudio is an integral part. Keywords: cultural landscape, adaptive decision-making processes, NAIADE method


Chronic limb threatening ischemia (CLTI), the most severe manifestation of peripheral artery disease, isaccompanied by high rates of limb amputation and death. There is a pressing need for novel therapydevelopment in these patients, which will require a thorough understanding of the individual cellularcontributions to ischemic limb pathology. BAG3 is a multifunctional adaptor protein that regulatesdiverse cellular functions. Mutations in
 BAG3
 now appear to be one of the most common to causedisease in the clinical setting, including predisposing Black patients to cardiovascular disease. Wepreviously identified a coding variant in
 Bag3
 that contributes to ischemic muscle necrosis after murinehindlimb ischemia (HLI) that was rescued by gene therapy, although we do not know which cell typesrequire Bag3 individually to mount efficient responses to ischemia. We hypothesized that vascularendothelial cell Bag3 would be required for both the restoration of blood flow and muscle function afterHLI. To test this hypothesis, we generated an inducible genetic model of endothelial cell
 Bag3
 deletion(Cdh5(PAC)-CreERT2;Bag3
 -/-
 ). At 20 weeks of age, mice were administered either tamoxifen (KO;
 n
 =20) orvehicle (CON,
 n
 =28) and evaluated at baseline or subjected to HLI for 7-days. Endothelial cell specific
 Bag3
 deletion was validated first by genotyping and then by qRT-PCR in flow sorted cells. KO did notalter animal body weights, heart or skeletal muscle wet weights, physiologic muscle function (extensordigitorum longus absolute or specific force) or muscle histology (no regression of limb muscle tissuevascular cells) at baseline when compared with CON. After HLI, KO did not cause limb tissue necrosis,reduce limb blood flow recovery (laser doppler perfusion imaging) or physiologic muscle function, anddid not worsen histological damage to the limb muscle when compared with CON. Our study providesevidence for the first time that loss of endothelial cell Bag3 does not exacerbate myopathy and delaylimb blood flow recovery after hindlimb ischemia and suggests that the benefits of Bag3 gene therapymay be driven by the muscle cell compartment of the ischemic limb.


Even if hardware improvements have increase the performance of embedded systems in the last years, resource problems are still accurate. In fact, the persisting problem is the constantly growing complexity of systems. In addition, new supports of service such as PDAs or smartphones increase the need for flexible and adaptable open software. Component-based software engineering tries to address these problems and one key point for development is the Quality of Service (QoS) coming from resource constraints. In this technical report, we recall the concepts behind Qinna, a component-based QoS Architecture, which was designed to manage QoS issues, and we illustrate the developpement of a image viewer application whithin this framework. We focus on the general developpement methodology of resource-aware applications with Qinna framework, from the specification of resource constraints to the use of generic Qinna's algorithms for negociating QoS contracts at runtime.


n.keiding(biostat.ku.dk SUMMARY In survival analysis of follow-up studies with staggered entry, it may be requested to examine a chance finding at an interim analysis in a confirmatory analysis based on 'independent evidence'. Keiding et al. (1987) suggested incorporating residual lifetimes of initial survivors into the confirmatory analysis and indicated heuristically that this provides valid independent evidence, assuming that the statistical model is true. The present paper provides a full mathematical proof of a much more robust result, namely that the re-use of original survivors provides an asymptotically independent confirmatory analysis even under a broad class of model misspecification, allowing unmeasured patient heterogeneity.


Modern mainstream programming languages distinguish between "atomic" (or sometimes "volatile") variables, and ordinary data. Atomic accesses are treated as synchronization constructs, and support concurrent access with well-defined semantics. In contrast, concurrent accesses to ordinary data, if at least one access is an update, constitute a data race. Code with data races does not have well-defined semantics. Such code may fail completely when recompiled or run on a different operating system version. In C and C++ data races are equivalent to assignments to out-of-bounds array elements; any data race can result in arbitrary failures, including application crashes, hangs, and inexplicably and completely wrong answers.
 These language specifications, combined with implementation realities, make it unsafe to exploit "benign" data races to obtain performance, even if we are willing to tolerate approximate answers. Furthermore, even if we happen to get lucky, and code with data races happens to execute correctly with our current compiler, data races provide at best inconsequential performance advantages over atomics. In fact, there are interesting, and probably common, cases in which data races provide only a minor performance advantage, even over pervasive locking to avoid them, it at sufficiently large core counts. We demonstrate such a case.


Post-earthquake fires cause significant harm to human populations. Based on the historical statistical data , the relation between fire number per 100 thousand square meters and peak ground acceleration(PGA) is simulated, and the fire cases are also simulated.


Hydrogen sulfide (H2S) is of vital importance in several biological and physical processes. The significance of H2S‐specific detection and monitoring is emphasized by its elevated levels in various diseases such as cancer. Nanotechnology enhances the performance of chemical sensing nanoprobes due to the enhanced efficiency and sensitivity. Recently, extensive research efforts have been dedicated to developing novel smart H2S‐triggered/therapeutic system (SHTS) nanoplatforms for H2S‐activated sensing, imaging, and therapy. Herein, the latest SHTS‐based nanomaterials are summarized and discussed in detail. In addition, therapeutic strategies mediated by endogenous H2S as a trigger or exogenous H2S delivery are also included. A comprehensive understanding of the current status of SHTS‐based strategies will greatly facilitate innovation in this field. Lastly, the challenges and key issues related to the design and development of SHTS‐based nanomaterials (e.g., morphology, surface modification, therapeutic strategies, appropriate application, and selection of nanomaterials) are outlined.


Foreword. Introduction. Part One: Evolution and Emergence of Web Services. Chapter 1: Evolution of Distributed Computing. Chapter 2: Introduction to Web Services. Part Two: Web Services Architecture and Technologies. Chapter 3: Building the Web Services Architecture. Chapter 4: Developing Web Services Using SOAP. Chapter 5: Description and Discovery of Web Services. Chapter 6: Creating .NET Interoperability. Part Three: Exploring Java Web Services Developer Pack. Chapter 7: Introduction to the Java Web Services. Chapter 8: XML Processing and Data Binding with Java APIs. Chapter 9: XML Messaging Using JAXM and SAAJ. Chapter 10: Building RPC Web Services with JAX-RPC. Chapter 11: Java API for XML Registries. Chapter 12: Using the Java Web Services Developer Pack: Case Study. Part Four: Security in Web Services. Chapter 13: Web Services Security. Part Five: Web Services Strategies and Solutions. Chapter 14: Introduction to Sun ONE. Further Reading. Index.


Published to coincide with "Private Eye"'s 30th anniversary, this contains the very best of the magazine's cartoons. It includes work by Heath, McLachlan, Larry, Ffolkes and many more.


PEACE was established by hospital administration in 2003 with the goal of addressing high cost and high volume medications and disease states. It runs parallel to the P&T Committee, and reports directly to hospital administration. In contrast, the P&T committee reports to the medical executive committee. Members of the committee include the Chief Medical Officer, the Chief Financial Officer, administrative representatives from the pharmacy and nursing departments, and the medical staff. The PEACE committee, through various benchmarking reports and internal analysis, identifies items that match the committee's goals. Following data collection and discussion, PEACE then forwards the analysis to the appropriate P&T subcommittee for further insight and guideline development. One of the first undertakings of the PEACE committee was to address the use of erythropoesis-stimulating agents (ESAs). Erythropoetin is a high cost medication used for red blood cell stimulation in patients with anemia. Given that the cost of this medication was greater than any other at the time, it became one of the committee's first projects. After identifying committee members with expertise in the area and gathering information from other institutions, PEACE chose the most appropriate agent from the class and developed evidence-based guidelines for the medication. The outcome was savings amounting to greater than half a million dollars per year.


A study from the Boston University School of Medicine shows that taking statins—usually prescribed to lower cholesterol and to reduce the risk of heart attacks and strokes—was associated with a 79% reduction in the risk of developing Alzheimer's disease.

Presented at the American Academy of Neurology's 54th annual meeting in Denver, Colorado, the as yet unpublished study confirms two previous studies that indicated a reduction in the risk of Alzheimer's disease, but this study is the largest of its kind in the …


Premise There is considerable variation in leaf lobing and leaf size, including among grapevines, some of the most well-studied leaves. We examined the relationship between leaf lobing and leaf size across grapevine populations which varied in extent of leaf lobing. Methods We used homologous landmarking techniques to measure 2,632 leaves across two years in 476 unique, genetically distinct grapevines from 5 biparental crosses which vary primarily in the extent of lobing. We determined to what extent leaf area could explain variation in lobing, vein length, and vein to blade ratio. Results Although lobing was the primary source of variation in shape across the leaves we measured, leaf area varied only slightly as a function of lobing. Rather, leaf area increases as a function of total major vein length, total branching vein length, and decreases as a function of vein to blade ratio. These relationships are stronger for more highly lobed leaves, with the residuals for each model differing as a function of distal lobing. Conclusions For a given leaf area, more highly lobed leaves have longer veins and higher vein to blade ratios, allowing them to maintain similar leaf areas despite increased lobing. These findings show how more highly lobed leaves may compensate for what would otherwise result in a reduced leaf area, allowing for increased photosynthetic capacity through similar leaf size.


A Rh-catalyzed asymmetric synthesis of silicon-stereogenic dihydrodibenzosilines featuring axially chiral 6-member-bridged biaryls is demonstrated. In the presence of Rh(I) catalyst with chiral diphosphine ligand, a wide range of dihydrodibenzosilines containing both silicon-central and axial chiralities are conveniently constructed in excellent enantioselectivities via dehydrogenative Csp3-H silylation. Absolute configuration analysis by single crystal X-ray structures revealed a novel silicon-central to axial chirality relay phenomenon, which we believe will inspire further research in the field of asymmetric catalysis and chiroptical materials.


Previous scoping studies suggested that the coal basins of the River Forth could provide a suitable site for the first UCG project in the UK. Other studies have indicated that the most significant environmental concerns for UCG are the risks of groundwater contamination through gas escape and leachate migration. Careful site selection, process control and post-gasification site management should minimise those risks.


This chapter reports on the findings of a contextual mixed-method study investigating the factors that influence how teachers at the Language Center (LC) of Sultan Qaboos University, Oman (SQU), assess students' academic writing and the features on which they focus. Results from the quantitative data analysis indicate that the influence of raters' first language (L1) is statistically significant, while the impact of their experience of teaching a particular course is effectively insignificant. Findings from the qualitative data analysis, however, reveal other influential factors, notably teaching experience in general terms, learning experience, educational background, culture, and personality. As for the features teachers focus on while assessing writing, both quantitative and qualitative data analyses show different patterns for the L1 groups involved. Findings from this study could be useful for informing decision makers on the various ways teachers from different L1 and experiential backgrounds assess writing and the constructs they follow.


Background. Development of early-ripening high-yielding cultivars of spring bread wheat is a complicated and difficult process. Striving for higher yields has triggered a trend to prolong the growing season pf the cultivars released by the Tatar Research Institute of Agriculture (TatRIA). Our breeding efforts to produce early cultivars, based on using an early-ripening sample as one of the parents, were unsuccessful. This paper presents a search for solutions to the said problem.Materials and methods. We studied spring bread wheat accessions from the collections of the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR) and Baicheng Academy of Agricultural Sciences (China) as well as promising lines developed by TatRIA. The study of the material was based on conventional spring bread wheat breeding methods. Phenological phases of wheat development were identified using the Zadoks scale.Results. An ambiguous role played by the vernalization response (Vrn) and photoperiod sensitivity (Ppd) genes in wheat earliness was shown, which is consistent with the data repeatedly presented in other publications. We identified accessions with the shortest period from sprouting to heading. Under our climate conditions, the earliest cultivars were those from Novosibirsk Province, Russia, and the North-Eastern China, where wheat development from sprouting to heading lasted 36–46 days.


We thank Power and Bird for their helpful insights and scholarly review of the literature. The question of bisphosphonate use in primary lymphoma of bone (PLB) is an intriguing one. We have not used bisphosphonates as adjunctive therapy for these patients because in our experience bone pain usually responds quickly to therapy. In absence of randomised data, perhaps the biologically closest disease from which to draw parallels is multiple myeloma, wherein bisphosphonates are used to prevent skeletal events. In PLB, unlike myeloma, recurrent skeletal events are rare. Therefore, the potential benefits of long-term therapy with bisphosphonates may be limited. Nevertheless, patients with persistent bone pain or those at risk for fracture might benefit from treatment. A direct antilymphoma effect of bisphosphonates remains a theoretical possibility that merits further study. Given the experience of Power and Healy Bird and the clinical and preclinical data they cite, shortterm use of bisphosphonates in selected patients with PLB could be justified.


Looking at the dynamics of the system described by the equation x(n + 1) = f (x(n)) one may say that coordinates of the vector x = {x 1 , x 2 ,. .. , x N } are updated synchronously. What happens with the system if coordinates of the vector x are updated asynchronously, i.e., if at a given moment n only coordinates with indices i from some set ω(n) ⊆ {1, 2,. .. , N } are changed in accordance with the law x i (n + 1) = f i (x(n)) while others remain intact? This is the main topic which is discussed in the paper.1 of the President of Russian Federation and by the project " Development of mathematical methods of analysis of distributed asynchronous computational networks " of the program of fundamental investigations of OITVS RAN (Branch of Information Technologies and Computer Systems of Russian Academy of Sciences) " New physical and structural methods in infocommunications " .


A detailed description of Nepenthes reindwardtiana Miquel is provided, and its distribution is reviewed. One new variety, N. reindwardtiana var. samarindaiensis Adam & Wilcock, from Kalimantan in Borneo is described.


The discounted value of cash flows of assets is negatively related to interest rates (i.e., the discount rate effect). However, economic activity is positively related to interest rates and positively related to the cash flows of assets with tariffs that can be adjusted to manage demand such as adjustable-rate toll roads, but uncorrelated to assets that do not bear demand risk such as non-toll roads (i.e., the cash flow effect). This effect arises in some types of assets from: (i) the positive correlation between economic activity and demand for the infrastructure assets; and (ii) the positive correlation between economic activity and inflation. We find that the cash flow effect dominates the discount rate effect for assets with tariffs that can be adjusted to manage demand and, therefore, the value of these assets increases in periods of economic expansion. Nevertheless, the opposite occurs for assets that do not bear demand risk.


A personal computer-based spreadsheet developed for an energy management program combines accounting and engineering methods to show how tracking electrical energy can keep energy management goals in focus. The author describes how to use the spreadsheet to compare power usage for each of four day types during a period when power usage has changed over the previous year. The spreadsheet has three major sections: exception tables, worksheets, and electrical energy trend graphs. Deviations from forecasted trends indicate changes in the base load can help the utility with load management. 3 figures, 3 tables.


The thesis describes various uses of clay materials in the construction of residential houses. The characteristics of the clay are described in the context of natural building materials. The following sections explain the technique of building houses by using clay materials. The main purpose of this thesis is to describe the use of clay material as a basic element of structural assemblies. The computer program U-Wert was used to calculate physical properties of heat transfer and vapor diffusion in selected cases of structural assemblies. Analyses showed that the house, built of clay and other natural materials is energy efficient and complies with all the requirements of the current Slovenian legislation. Characteristics of thermal insulation and protection against moisture are comparable to
other modern building materials. It is evident clay houses are adequate with ecological standards about transport, recycling and energy saving.


Cullingford's editorial approach sets an engaging pace in this fresh look at mentoring and education. Focusing on teacher education and choosing to introspect the differences between rhetoric and reality in all of the studies explicated, contributing authors draw our attention to the generic complexities inherent in teacher professional learning (chapters 5, 12). Although acknowledging that mentoring episodes are natural events and central to the learning processes of teachers across the globe (p. xvi), they critique the training of mentors and mentees where existing power and control mechanisms are resituated within mentoring relationships (chapters 1, 8); review the adequacy of mentoring as a stand alone, mechanism in school based teacher training (chapter 4); investigate the availability and expenditure of teacher time during mentoring partnerships (chapter 1, 2); compare the tensions and successes that arise between teaching, supervisory, peer group and mentoring roles related specifically to formal, documented national education system frameworks (chapters 2, 7, 9); and examine the efficacy of mentoring as a human resource capability building strategy, particularly during induction phases to the profession (chapters 3, 6,10) and, describe the influences of e-technologies upon mentoring relationships (chapter 11). Mentoring in education provokes interest because it places specific emphasis upon the perennial conundrum, is a teacher a mentor? Cullingford (p. 3) argues that mentors have always been supervisors in disguise and bases his claim on his derivation of the word mentor from the English monitor—a markedly different stance from most other researchers working in the field who cite its origin as mentes from the Greek for thinker. Warren (p. 12) notes that it is professionally more acceptable to have teachers who teach prospective or experienced teachers referred to as mentors. Ganser (p. 38) concurs but draws our attention to the sharp distinction observed between mentors who train pre-service teachers to those who facilitate professionally developed graduates. Jones (p. 58) uncovers the core of the problem when she discusses the ambivalence that exists between the use of the terms tutor and mentor, acknowledging that there is a tension concerning how a mentor is viewed today, not as a protector or friend but as an assessor, accreditor, head of department or supervisor (p. 59). Britton (p. 108) argues that society and the teaching profession have moved on and cites the effective use of a mentoring triad comprising a primary mentor (usually a department head), an advice and guidance coordinator (a deputy principal) and a buddy teacher (stepahead peer) to support the mentoring of colleagues being inducted to Asia-Pacific Journal of Teacher Education Vol. 35, No. 4, November 2007, pp. 455–458


The present invention relates to a nanoemulsion cosmetic composition comprising a complex fermented extract of walnuts and chestnuts as an active ingredient, having the particle diameter of 80-110 nm. The present invention comprising a fermented extract of a natural substance as an active ingredient is safe with respect to the skin, has excellent skin compatibility, absorptive capacity, and excellent long-term stability, and exhibits excellent effects in preventing skin aging and reducing wrinkles. In addition, the composition is easy to adjust the particle diameter, can be applied by skin types by applying a nanoemulsion method with excellent percutaneous absorption, and can minimize skin trouble-inducing factor by using a small amount of skin care ingredients.


The Pringle manoeuvre can be applied during liver resection to reduce blood loss. During this procedure, inflow of blood into the liver is occluded through clamping of both the portal vein and hepatic artery in the hepatoduodenal ligament. This induces portal congestion in the splanchnic bed and


Partial oxidation of methanol to formaldehyde on silver catalyst represents an important industrial process
due to the versatility of formaldehyde as an intermediate in chemical synthesis. The development of
kinetic models is essential for a quantitative description of the concentration of the chemical species
involved in the process as well as for process design and optimisation purposes. However, the
development and identification of reliable kinetic models is strictly related to the execution of informative
experiments, allowing for the elucidation of the complex reaction pathways involved in the oxidation
process and providing a precise estimation of the kinetic parameters for each model proposed in the study.
In this paper a model-based design of experiments (MBDoE) approach is used for planning optimally
informative experiments for the development of kinetic models of methanol oxidation on silver catalyst.
Experiments are carried out in microreactor platforms where better reaction temperature control,
accelerated heat and mass transfer and enhanced mixing of reactants can be achieved.


This paper investigates public opinion on the Swiss CO2 levy and its 2020 revision by using a discrete choice experiment answered by a sample of 586 respondents living in Switzerland. The experiment is designed to elicit citizen preferences among various taxation attributes and is followed by a referendum voting experiment on various CO2 levy proposals. Based on latent class modeling approaches, we find that the population is composed by two distinct but relatively preference profiles: Environmentalists and Neutrals. Respondents belonging to the first group tend to favor higher carbon tax rates and a redistribution of proceeds benefiting low-income individuals, whereas those in the second group prefer lower rates and a uniform redistribution of proceeds across all taxpayers. Findings from the voting experiment point to a general support among the Environmentalists, but an uncertain approval from the Neutral group.


A valuable approach lo understanding the forces that maintain protein structure is to analyze the thermodynamic effects of mutations on protein folding. The folding process is most often described using an energetic model that assumes a two‐state transition between the native and denatured states. However, some results obtained using this approach for mutants of the protein staphylococcal nuclease have contradicted expectations from our current understanding of protein energetics. The application of differential scanning calorimetry to a set of mutant nuclease proteins allowed us to measure directly the effects of mutations on the enthalpy and heat capacity changes of unfolding, as well as on the cooperativity. We found that most of these effects can be understood with a three‐state model of folding including a distinct intermediate, but not with the two‐state model. Use of a three‐state instead of a two‐state model leads to large differences in conclusions about the stability effects of some mutations, suggesting that réévaluation of the effects of mutations on this and other proteins may be necessary to achieve an accurate description of folding energetics. The two‐state assumption commonly used in protein stability studies may be an oversimplification in many cases.—Carra, J. H., Privalov, P. L. Thermodynamics of denaturationof staphylococcal nuclease mutants: an intermediate state in protein folding. FASEB J. 10, 67‐74 (1996)


The utility model discloses a wind power device. The wind power device comprises an energy storage air bag, a barrel shell, a rotating shaft and an impeller, wherein the impeller is arranged on the rotating shaft and in the barrel shell; the rotating shaft is arranged on the barrel shell; the barrel shell comprises two closed ports; the tangential position at one edge of the barrel shell is provided with an air inlet pipe, and the tangential position at the other edge of the barrel shell is provided with an air outlet pipe; and the air inlet pipe is communicated with the energy storage air bag through a pipeline. One end of the rotating shaft outside the barrel shell is provided with a transmission gear, and compressed air of the energy storage air bag can push the impeller to rotate directly through the pipeline so as to drive the rotating shaft; and the mechanical energy can be output by the transmission gear. The wind power device has the advantages of simple equipment, low manufacturing cost and high efficiency.


The problems of adhesive binding technology affecting books' final quality such as experience-based process controlling,poor coordination,and unfitting for product features were discussed.A set of production process optimization solution was established according to GB CY/T-series standard,combined with homemade accurate test format,and supported by martini adhesive binding linkage line.The solution has important function to improve production efficiency,reduce defective index,and strengthen enterprises' competitiveness.The purpose was to reference for improving product quality of domestic book publishing enterprise.


According to the sequence of sikSAD gene from GenBank,we cloned sikSAD gene from Sasussured involucrata Kar.et Kir though RT-PCR,and constructed the recombinant E.coli/Yeast shut-tle vector pYES2-sikSAD.Then it was transformed into S288C yeast by electroportion method,PCR and SDS-PAGE analysis indicated that sikSAD had been integrated into the genome.That the recombinant vector had been transformed into yeast.Finally,we made preliminary analysis on the resistance and analysis of variance under low temperature stress and ethanol tolerance.The results suggest that the recombinant yeast pYES2-sikSAD can not only survive in low temperature but also grow well at 28 °Cin the experiment of low temperature stress,the percentage of oleic acid have obvious change.In the experiment of ethanol tolerance,the recombinant yeast pYES2-sikSAD can tolerant certain concentration of ethanol,also the ability of tolerance increased more than 10 percentage compared with non-transformed yeast.The above testify that the recombinant yeast pYES2-sikSAD have more tolerance and excellent activity and growth advantage under the low temperature and high ethanol.This ex-periment using molecular technology to reconstruct yeast which can provide the basement for producing Saccharomyces cerevisiae with higher quality in industry.


The term "domestication syndrome" describes a range of correlated trait changes seen in domesticated populations when compared to their wild relatives or ancestors (Jensen, 2006;Wilkins et al., 2014; Zeder, 2015). Controlled experimental breeding has demonstrated rapid emergence of this syndrome in several mammal populations selected for dampened reactive aggression and stress response (Trut, 1999; Jensen, 2006; Kulikov et al., 2016). These results confirm findings of correlated change from longstanding observational research in domesticated lineages (Hemmer, 1990). Known traits include: docile behavior; reduced sexual dimorphism; reduced prognathism; smaller teeth; skeletal gracility; reduced brain sizes; altered oestrus cycles and fertility; floppy ears; elevated vocal communication; and altered pigmentation (Hemmer, 1990; Wilkins et al., 2014; Sánchez-Villagra et al., 2016; Okanoya, 2017). Many of these features are known to appear rapidly, as heterochronic shifts in ontogeny (i.e., paedomorphism or neoteny), rather than as isolated and adaptive mutations (Belyaev, 1979; Trut, 1999; Jensen, 2006; Zeder, 2012, 2015). Heritable hypoplasia of neural crest cell-derived tissues provides the most widely supported proximate explanation for these observed trait correlations (Wilkins et al., 2014). Interestingly, several traits seen in bonobos (Hare et al., 2012) and in humans (Groves, 1999; Leach, 2003; Cieri et al., 2014; Thomas and Kirby, 2018) suggest intraspecific interactions can drive a process of "self-domestication" via socio-sexual selection for higher social tolerance and less reactive aggression (Cieri et al., 2014; Hare, 2017; Wrangham, 2018). InHomo sapiens, this process is thought to have enabled an expanded cooperative ability, leading to improved language and knowledge-sharing, thereby promoting social complexity and technological advancement (Hare, 2017; Thomas and Kirby, 2018). Humans are also characterized by an outstanding capacity for integration between brain, body and tools, and the evolution of this ability is associated with neuroanatomical changes of the visuospatial association cortex (Bruner, 2018). Whilst current scholarship is yet to address the potential for interaction between self-domestication and body cognition, we hypothesize that there may be value in an examination of any overlap. As such, here, we consider whether and to what extent these phenomena shared common evolutionary factors or reciprocal influences.


The present invention relates to a method and system for enabling a user to interact with computer software running on a computer system. The interface surface including the code data includes information relating to the computer software indicative of at least one of the interacting components relating to the computer software is provided to the user. A sensing device in the form of light sensing stylus includes an identification data indicating the identity of the user. When using the write by the user with the stylus or the stylus as a pointer, the operation end of the stylus is in contact with the interface surface. It said sensing device senses the display data representative of the at least one interactive component using said at least some code data. The computer system receives the identification data and the display data from the sensing device. The interactive component in the computer system is identified by using the display data, the user data is identified using the identification data. The computer software is operating, at least in part dependent on the user data in accordance with instructions associated with the at least one of the interacting components.


Hydatid disease is a parasitic disease endemic in Romania which occurs frequently in liver and lungs, but it can also be present in almost any part of the body. We present the rare case of a 37-year-old male which was admitted in our service with a large hydatid cyst at the level of the right thoracic outlet and we were not able initially to establish its exact origin, liver or right lung. After imagistic investigations we decided for an abdominal approach considering that the cyst was liver related. Intraoperative findings showed a primary hydatid cyst of the diaphragm, a very rare entity that was successfully treated by the mentioned approach.


In the text of the Zhouyi,there are six characters of Jian 艰,specifically in the statements of hexagrams of Shike,Daxu, Mingyi,Tai,Dazhuang,Dayou and so on. It should be called Xian 限,means limitation and restriction. Character Gen 艮 and Xian 限 are cognate words with the same pronunciation. So,it is not tenable to interpret character of Jian 艰 as difficult and regard characters Han 暵 and Gen 根 as its original character.


The developmental rate of eggs and juveniles of the spider Ornithoctonus huwena was determined at five different temperature and three different humidity.The result indicated that temperature was the most important element that affected the development of this spider,and humidity influenced the stages of its eggs and juveniles remarkably.Optimum seeking method was used to calculate the threshold temperature and effective temperature sum of Ornithoctonus huwena .As the result,the threshold temperature for egg and whole generation of this spider were determined to be 14 3 ℃ and 7 0 ℃,and the effective temperature sum for these stages were 712 66 and 6161 80 degree day respectively.


The notion of normal numbers was first introduced by Emile Borel [3] in 1909. He considered the decimal expansion of real numbers in the unit interval to the base r and assuming that every digit of their decimal expansions is independent and also takes all possible values 0,1, ・ ・・ and r-1 with equal probability, he proved that almost all real numbers are normal to the base r in the sense of Lebesgue measure. For a real number w, we denote {w} the fractional part of w defined by


The world is moving towards hygienic and there is a need for hygienic products in modern lifestyle. It is an opportunity to grow the textile market by meeting the expectation through textile products finished with antimicrobial properties. Multidrug-resistant organisms are increasingly implicated in acute and chronic wound infections, thus compromising the chance of therapeutic options. This paper focuses on a wound dressing with extract from natural sources of neem leaves and turmeric. The efficacy of the product was evaluated by various physical and biochemical tests.


The weak bosons are bound states. The state with the lowest mass is identified with the boson, which has been discovered at the LHC. The p-wave excitations are studied. Specific properties of the excited bosons are discussed, in particular their decays into weak bosons and photons. The stable fermion, consisting of three fermions, provides the dark matter in our universe.


This article presents a comparison between two PM synchronous electrical motors of 0?5kW, a single phase machine and a three-phase machine designed for automotive applications. The single-phase structure developed by our laboratory displays the particularity of being completely symmetric: no mechanical or electromagnetic asymmetry. This machine starts with the maximum electromagnetic instantaneous torque and thus the corresponding current at the moment of start-up is very low. Both single and three-phase motor drives are designed with the same specifications. The calculation and optimization of electromagnetic parts are obtained thanks to the use of a corrected 2D finite element code in order to take into account the strongly three-dimensionnal aspect of these machines. The experimental results and projection made using a 3D finite element code will serve to validate our method, which includes saturation problems. A simulation of electrical equations is also developed and validated for each kind of motor inverter structure presented.


Dexrabeprazole [R(+) rabeprazole] is a novel proton - pump inhibitor which is used in treatment of acid peptic diseases, gastroesophageal reflux disease ( GERD ) maintenance therapy, erosive esophagitis, short - term treatment of active duod enal and zollinger - ellison syndrome and treatment of H.Pylori - induced ulcers. This review explains superiority of dexrabeprazole (at half the recommended rabeprazole dose) over rabeprazole in terms of favo urable pharmacokinetics, more efficacy , longer half - life, better hea ling of esophagitis, and fastly symptom control.


MC4R, обычно не сопровождается изменениями других физиологических функций. Resume. Mutations in LEP, LEPR, PNC and MC4R genes induce obesity and deterioration of other physiological functions. Blockage of LEP and LEPR expression in homozygotes leads to severe obesity, delay in sexual development, insulin resistance, decreased secretion of pituitary hormones and immunodeficiency. Mutations of POMC in homozygote variant are associated in humans with morbid obesity and acute adrenocortical deficiency. In heterozygotes mutations of POMC predispose to obesity, but have no influence on other functions. Mutations in MC4R gene are the most common cause of obesity. They are associated with severe deterioration of lipid metabolism in homozygotes, but with more mild pathology in heterozygotes. Obesity from the mutation in MC4R gene usually is not accompanied by changes in other physiologic function.


The newly dicovered complete corpus of the Jewish poll-tax lists provides a totally new outlook on Jewish autonomy in eighteenth century Poland from which a full reconstruction of the Jewish settlement can be drawn. The book includes series of tables and maps.


By carefully selecting the fluence of a nanosecond laser beam interacting with a thin indium target, we have discovered solidified fossils of micron-sized nonlinear and breaking surface waves. These are likely the result of a driven capillary-gravity wave. The physics is relevant to the area of laser-matter interactions and processing.


Hot impinging air jets are usually used to increase heat and mass transfer. The dehydration of materials is a procedure of common significance in the chemical processes, forensic science and food i...


This study explored the Fisher separation theorem and capital budgeting decisions of quoted firms on the Nigerian stock exchange. A sample of 60 questionnaires were filled and returned by staffs from particular sectors like manufacturing, health and agriculture.  Descriptive statistics was employed to illustrate the data while the Spearman rank order correlation test was used to determine if a significant relationship exist among the variables. From the estimates, the Net Present Value and Modified Internal Rate of Return are regularly employed by firms in making capital budgeting decisions. Also, when firms employ capital budgeting tools, it creates wealth for both managers and shareholders, providing support for the Fisher's separation theorem. Finally, a correlation coefficient of 0.827 reflect a positive and linear relationship between capital budgeting decision and Shareholders' value creation. Thus, an increase in capital budgeting decisions result to an increase in value creation. This outcome is consistent with findings from other economies and previous studies. It thus recommends that firms in the Nigerian environment should ensure they play down on shareholders' desire for dividends and instead redirect their funds to more investments by employing suitable capital budgeting decisions.


Sputtered amorphous Ge_4Sb_1Te_5, Ge_1Sb_2Te_4, Ge_2Sb_2Te_5, and Ag_0.055In_0.065Sb_0.59Te_0.29 thin films were studied by differential scanning calorimetry. Upon continuous heating, heat release due to structural relaxation of the amorphous phase between 0.5 and 1.0 kJ/mol was observed. This value depends on the thermal history of the sample. Preannealing of the amorphous phase revealed the glass transition temperature T _g within 10 K of the crystallization temperature upon continuous heating at 40 K/min.


In their article "The Street Performer Protocol and Digital Copyrights" (Kelsey and Schneier, 1999) suggest that copyright will become increasingly difficult to enforce. They propose a general mechanism for funding digital public works, the "Street Performer Protocol" in which authors produce their work only after they receive enough contributions to make it worth their while. In this article, I sketch out a proposal for the creation of a software completion bond market. I think such a market would be a practical implementation of the "Street Performer Protocol" for the funding of open source software. I first describe how such a bond market might work, and why I think the open source community needs a bond market. Then I examine the underlying economics of open source software. Finally, I review some of the existing and potential alternatives to a software completion bond market. [1].


El Shaddai (the name reportedly comes from that used by Abraham for God in the Old Testament) is one of the more remarkable popular religious movements in the world today. With a following of some 9 million to 11 million in the Philippines and abroad, it is signif icantly larger than other prosperity movements. Moreover, it differs from similar movements particularly in that it remains — however, uncomfortably — within the fold of an established denomination, in this case the Catholic Church. In this work, Wiegele attempts to understand, from an anthropological point of view, the dynamics of its growth and its impact on Philippine Catholicism. Begun in Manila in 1981 as a nondenominational Christian radio programme featuring sermons by "Brother Mike" Velarde, a businessman and real estate developer, El Shaddai struck a responsive chord especially among the poor in the slums. Soon after beginning his program, Velarde identified himself with the Catholic charismatic movement. After more than 20 years of phenomenal growth, his movement now brings together up to a million followers for allnight weekly prayer meetings and healing rallies in one of the largest parks in Metro Manila; the meetings are telecast and broadcast by radio throughout the country, there are El Shaddai chapters in practically every province of the Philippines and in 35 countries abroad, tapes of Velarde's sermons circulate widely, and he is a significant force in national politics. Without any formal training in theology, he appears to have derived much of the content of his preaching from American TV evangelists of the "prosperity gospel", which emphasizes healing, health, and prosperity as God's gifts to the righteous, and "positive confession" (publicly professing one's faith in the Lord's promises). He teaches that by tithing and the making of "seed faith" offerings, the faithful follower puts God in his debt, and by his "positive


The Earth's magnetic field is measured on and above the crust, while the turbulent dynamo in the outer core produces magnetic field values at the core–mantle boundary (CMB). The connection between the two sets of values is usually assumed to be independent of the electrical conductivity in the mantle. However, the turbulent magnetofluid in the Earth's outer core produces a time-varying magnetic field that must induce currents in the lower mantle as it emerges, since the mantle is observed to be electrically conductive. Here, we develop a model to assess the possible effects of mantle electrical conductivity on the magnetic field values at the CMB. This model uses a new method for mapping the geomagnetic field from the Earth's surface to the CMB. Since numerical and theoretical results suggest that the turbulent magnetic field in the outer core as it approaches the CMB is mostly parallel to this boundary, we assume that this property exists and set the normal component of the model magnetic field to zero at the CMB. This leads to a modification of the Mauersberger–Lowes spectrum at the CMB so that it is no longer flat, i.e., the modified spectrum depends on mantle conductance. We examined several cases in which mantle conductance ranges from low to high in order to gauge how CMB magnetic field strength and mantle ohmic heat generation may vary.


Conventional geotechnical instrumentation techniques available for monitoring of slopes, especially soil-nailed slopes have limitations such as electromagnetic interference, low accuracy, poor longterm reliability and difficulty in mounting a series of strain sensors on a soil nail bar with a small-diameter. This paper presents a slope monitoring system based on fibre Bragg grating (FBG) sensing technology. This monitoring system is designed to perform long-term monitoring of slope movements, strains along soil nails, and other slope reinforcement elements. All these FBG sensors are fabricated and calibrated in laboratory and a trial of this monitoring system has been successfully conducted on a roadside slope in Hong Kong. As part of the slope stability improvement works, soil nails and a toe support soldier-pile wall were constructed. During the slope works, more than 100 FBG sensors were installed on a soil nail, a soldier pile, and an in- place inclinometer. The paper presents the layout and arrangement of the instruments as well as the installation procedures adopted. Monitoring data have been collected since March 2008. This trial has demonstrated the great potential of the optical fibre monitoring system for long-term monitoring of slope performance. The advantages of the slope monitoring system and experience gained in the field implementation are also discussed in the paper.


Movement learning is one of basic methods for man to understand the world. In the field of movement learning, body is both cognitive instrument and cognitive object. The course of learning new action is the same as other kinds of cognition. It is to set up the unification relation between subject and the world, meanwhile to be existent of that relation. The process of movement learning is such a cognitive course in which subject (mind) and object (body) go from being seperate to united.


The conversion efficiency of broadband InGaAs quantum dots-in-a-well (DWell) solar cells has been improved by optimizing the p-type doping and growth temperature for the DWell. The solar efficiency (η) is 130% times of the counterpart of GaAs baseline cell. Moreover we obtain the best photovoltaic result by inserting matrix pattern instead grid pattern and using wet etching to enhance the conversion efficiency. The photovoltaic characteristics shows an efficiency of 10.86%.


In this paper, a demonstration of DNA computing for k-shortest paths of a weighted graph is realized by biochemical experiments in such a way that every path is encoded by oligonucleotides and the length of the path is directly proportional to the length of oligonucleotides. For initial pool generation, parallel overlap assembly is employed for efficient generation of all candidate answers. During the computation, after the initial pool of solution is subjected to amplification, which is polymerase chain reaction, k-shortest paths could be separated by gel electrophoresis and the selection can be made at last


Over many years, laboratory testing of platelet aggregability have been carried out in attempts to develop drugs that would prevent thrombosis in arteries. The problems encountered included the question of methodology. Blood samples have to be anticoagulated in order to study the platelets. Anti-coagulation with citrate and tests on derived platelet rich plasma did not correlate at all well with thrombus growth in the stenosed coronary arteries of experimental animals and citrate removes the calcium ions which are vital for platelet function. Anticoagulation with heparin also interfered with platelet function, so that now, hirudins are the preferred anticoagulant. However it was observed that if, instead of stimulating platelet aggregation with adrenaline or ADP, serotonin was applied to the preparation, very little aggregation took place in spite of serotonin 5HT2A antagonists being the most potent inhibitors of thrombus growth in experimental animals. Another indicator that primary platelet agggregation is not a predictor of in vivo efficacy was the finding that 5HT2A antagonism inhibited aggregate growth. In a stenosed artery the platelets are activated by increased shear stress and blood turbulence with release of platelet serotonin causing positive feedback activation of more platelets. At present, there does not seem to be a bench in vitro test that accurately predicts in vivo efficacy in stenosed artery occlusive thrombosis.


In this paper, we investigate the relationship between argumentation structures and (a) argument content, and (b) the holistic quality of an argumentative essay. Our results suggest that structure-based approaches hold promise for automated evaluation of argumentative writing.


Sheets of salt and ductile shale advancing beyond the thrust front of the Gibraltar Arc (Iberian–Moroccan Atlantic continental margin) triggered downslope movements of huge allochthonous masses. These allochthons represent the Cádiz Nappe, which detached from the Gibraltar Arc along low‐angle normal faults and migrated downslope from the Iberian and Moroccan continental margins towards the Atlantic Ocean. Extensional tectonics initiated upslope salt withdrawal and downslope diapirism during large‐scale westward mass wasting from the shelf and upper slope. Low‐angle salt and shale detachments bound by lateral ramps link extensional structures in the shelf to folding, thrusting and sheets of salt and shale in the Gulf of Cádiz. From backstripping analyses carried out on the depocentres of the growth‐fault‐related basins on the shelf, we infer two episodes of rapid subsidence related to extensional collapses; these were from Late Tortonian to Late Messinian (200–400 m Myr−1) and from Early Pliocene to Late Pliocene (100–150 m Myr−1). The extensional events that induced salt movements also affected basement deformation and were, probably, associated with the westward advance of frontal thrusts of the Gibraltar Arc as a result of the convergence between Africa and Eurasia. The complexities of salt and/or shale tectonics in the Gulf of Cádiz result from a combination of the deformations seen at convergent and passive continental margins.


The Kagome lattice exhibits rich quantum phenomena owing to its unique geometric properties. Appealing realizations are the Kagome metals AV$_3$Sb$_5$ (A = K, Rb, Cs), where unconventional charge density wave (CDW) is intertwined with superconductivity and non-trivial band topology. Several experiments suggest that this CDW is a rare occurrence of chiral CDW characterized by orbital loop current. However, key evidences of loop current, spontaneous time-reversal symmetry-breaking (TRSB) and the coupling of its order parameter with the magnetic field remain elusive. Here, we investigate the CDW in CsV3Sb5 by magneto-optic polar Kerr effect with sub-microradian resolution. Under magnetic field, we observed a jump of the Kerr angle at the CDW transition. This jump is magnetic-field switchable and scales with field, indicating magneto--chirality coupling related to non-trivial band topology. At zero field, we found non-zero and field-trainable Kerr angle below CDW transition temperature, signaling spontaneous TRSB. Our results provide a crucial step to unveil quantum phenomena in correlated Kagome materials.


One stream of research for order of entry effects focuses on the possibility that the order of entry exerts a direct impact on business performance. A second stream of research, the contingency perspective, debates the merits of whether the order of entry, in combination with other market strategy and marketplace variables, is what actually drives business performance. The findings from studies focusing on possible direct effects offer only mixed evidence in favor of a pioneering advantage. The contingency perspective, however, has not been subjected to systematic, empirical scrutiny. Against this backdrop, the authors conduct a meta-analysis of the pioneering-market share findings and an examination of the contingency perspective of order of entry effects. The findings from the meta-analysis reveal that, on average, earlier entry is associated with greater market share. The findings from the contingency analysis, however, offer evidence suggesting that the contingency perspective is the more valid perspective for capturing the association between order of entry and market share. The authors discuss the theoretical and managerial implications of their findings and several directions for further research.


Relevance feedback has proven to be a highly effective technique for improving information retrieval (IR) resuits. After presenting the basic IR models and their associated relevance feedback techniques, we show how new computational models such as genetic algorithms and connection& processing can be used to further improve relevance feedback techniques and ultimately, retrieval performance. 1 Information Retrieval Systems Information retrieval has been the subject of much research over the last several years, largely due to the imprecise nature of determining which textual records are relevant to user queries. Prior research has been involved with indexing, determining which terms to use for top ica.lly. There is consensus in the information retrieval field that relevance itself is au imprecise concept. Recent research has identified factors other than topically that h&e influenced subjects' evaluations of the relevance of information fBarrv. 1994). includinn readability, that might be qua&tied-&d indiuded in &e indexing process. One can view an information retrieval system in a variety of ways. One way is to consider it ss a set of records that are identified, acquired, indexed, and stored and as a set of user queries for information that are matched to the index to determine which subset of the stored records should be retrieved and presented to the user. The index can involve descriptive information (i.e., bibliograiphic information in the case of textual documents, such as author, title, publisher, or year of publication), and content indicators (such as keywords or subject headings) to indicate the nature of what the document is about. We can be following way 'n to model the retrieval system in the & raft., 1985): D = a set of documents or records, T = a set of index terms (single words or phrases), F = an indexing function, where F : D x T [0, l] Q = a set of user queries for documents, a = a,;u,e,ry term weighting function, where 4 : Q x T --) "Permission to copy without fee all or part of this material is granted provided that the copies are not made or distributed for direct commerical advantage, the ACM copyright notice and the title of the publication and its date appear, and notice is given that copying is by permission of the Association for Computing Machinery. To cop:y 482 otherwise, or to republish, requires a fee and/or specific permission."


The results of modern dynamics of political identity in connection with trends of party building are presented. The influence of middle class on party building is considered. Besides, the influence of changes in social-economic structure of the population on transformation of role and essence of parties as social institute is analyzed. it is marked that the same processes not equally influence on political systems of different states, being at different stages of maturity of civil society. The decrease of traditional ideologies on social-political life is shown.


We report herein a novel infinite two-dimensional water morphology, found in a metallo-organic host, made up of discrete cyclic water hexamers and which contains large circular holes defined by 18 molecules of water.


A unique assemblage of tropical and temperate marine organisms characterizes the Houtman Abrolhos Islands, four clusters of islands and reefs off the coast of mid-Western Australia. Four reef observation areas or marine protected areas (MPAs) were established in 1994 to examine their value in protecting vulnerable reef fish species, including the sub-tropical wrasse, Choerodon rubescens, and the coral trout, Plectropomus leopardus. In 1993 and 1994 (prior to protection), population densities and body sizes were monitored at two island groups (Easter and Wallabi). At each location, the MPAs and the equivalent 'control' areas to remain open to fishing were monitored by underwater visual censuses. These closed and open areas were subsequently monitored four more times between 1995 and 2002 to assess long-term trends in abundance and population structure. Populations of the wrasse, C. rubescens, did not appear to respond to protection, exhibiting irregular fluctuations in both closed and open areas throughout the study. In contrast, although there were no significant increases for P. leopardus for the first three years of closure, after eight years of protection there were significantly larger numbers of P. leopardus in the closed areas. There was a three-fold increase at the Easter Group and a seven-fold increase at the Wallabi Group, relative to open fishing areas, attributed primarily to reduced fishing mortality. Significant closed areas (17% of the P. leopardus habitat) provided substantial stock-wide impacts. The data also indicate that the MPAs can be effective where some forms of fishing (such as lobster fishing) are permitted which are compatible with the objectives of the MPA. While MPAs are clearly an effective tool for increasing the local abundance of some reef fishes, the spatial and temporal scales required for their success may vary among species.


Objective To analyze and understand the epidemic situation of intestinal helminthe infection in wild tree shrews( Tupaia belangeri Chinensis),and to provide useful reference and support for prevention and treatment of parasitic infection in tree shrews. Methods 203 wild tree shrews were used in this study. Stool ova in the smear from fresh feces and after incubation were observed and identified by routine microscopic examination. Cestodes were observed in press slide after fixation and staining,and nematodes were observed under a stereoscope after clearing. The ova were identified with corresponding adult parasites. Results In this survey,we found the total prevalence rate of intestinal helminthes in this wild tree shrew population was 75. 86%,mainly including three kinds of important parasites,namely,Hymenolepis diminuta 27. 67%,Rictularia sp. 30. 06%,and Strongyloides stercoralis 51. 52%,respectively. Mixed infection rate of the three species was 4. 55%. For Rictularia sp. and Strongyloides stercoralis,embryonated eggs were often observed in their fresh feces. Conclusions Intestinal helminth infection rate is rather high in the wild tree shrews.Quarantine inspection is necessary for new intake. Different control measures and surveillance should be taken to control the dissemination of intestinal helminth infection in tree shrews.


Parkinson's Disease (PD) is a neurodegenerative disorder characterized by symptoms like resting and action tremors, which cause severe impairments to the patient's life. Recently, many assistance techniques have been proposed to minimize the disease's impact on patients' life. However, most of these methods depend on data from PD's surface electromyography (sEMG), which is scarce. In this work, we propose the first methods, based on Neural Networks, for predicting, generating, and transferring the style of patient-specific PD sEMG tremor signals. This dissertation contributes to the area by i) comparing different NN models for predicting PD sEMG signals to anticipate resting tremor patterns ii) proposing the first approach based on Deep Convolutional Generative Adversarial Networks (DCGANs) to generate PD's sEMG tremor signals; iii) applying Style Transfer (ST) for augmenting PD's sEMG signals with publicly available datasets of non-PD subjects; iv) proposing metrics for evaluating the PD's signal characterization in sEMG signals. These new data created by our methods could validate treatment approaches on different movement scenarios, contributing to the development of new techniques for tremor suppression in patients.


Multivariate adaptive regression splines (MARS) are a useful tool to identify
linear and nonlinear effects and interactions between two covariates. In this dissertation a new proposal to model survival type data with MARS is introduced. Martingale and deviance residuals of a Cox PH model are used as response in a common MARS approach to model functional forms of covariate effects as well as possible interactions in a data-driven way. Simulation studies prove that the new method yields a better fit to the data than the traditional Cox PH approach.
The analysis of real data of the German Heart Center on survivors of an acute myocardial infarction also documents the good performance of the method.


An Artificial Neural Network based modeling technique has been used to study the influence of different combinations of meteorological parameters on evaporation from a reservoir. The data set used is taken from an earlier reported study. Several input combination were tried so as to find out the importance of different input parameters in predicting the evaporation. The prediction accuracy of Artificial Neural Network has also been compared with the accuracy of linear regression for predicting evaporation. The comparison demonstrated superior performance of Artificial Neural Network over linear regression approach. The findings of the study also revealed the requirement of all input parameters considered together, instead of individual parameters taken one at a time as reported in earlier studies, in predicting the evaporation. The highest correlation coefficient (0.960) along with lowest root mean square error (0.865) was obtained with the input combination of air temperature, wind speed, sunshine hours and mean relative humidity. A graph between the actual and predicted values of evaporation suggests that most of the values lie within a scatter of ±15% with all input parameters. The findings of this study suggest the usefulness of ANN technique in predicting the evaporation losses from reservoirs. Keywords—Artificial neural network, evaporation losses, multiple linear regression, modeling.


Currently, chemo-therapy is still the main strategy for cancer treatment. However, chemo-therapy resistance remains its main challenge. Disulfiram [DSF] is a drug approved by FDA for the treatment of alcohol addiction, but it is later discovered that it has the anticancer activity. Importantly, there have been many literatures reporting that DSF can be used as a chemo-therapeutic sensitizer to enhance the anticancer activity of chemo-drugs in a variety of cancers. Furthermore, the combinations of DSF and chemo-drugs have been tested in clinic trials. In the review, we summarized the possible molecular targets and mechanisms of DSF to reverse chemo-resistance. We also further discussed the opportunities and challenges of DSF as a chemo-therapeutic sensitizer. In conclusion, DSF could be a potential repurposed drug to sensitize cancer cells to chemo-therapy in clinic.


Studies on Eldana saccharina have shown that populations from western Africa have distinct behavioural differences when compared with populations from eastern and southern Africa. In addition, the parasitoid guilds attacking these populations in the different regions are markedly different. The parallel geographical variation in these patterns between several widespread populations of E. saccharina evoked the hypothesis of diversification. To evaluate this hypothesis, a molecular analysis of the Cytochrome Oxidase c subunit I (COI) region of the mitochondrial DNA was conducted on populations of E. saccharina from various parts of Africa. Results of the current study reveal the presence of genetic variation in E. saccharina populations, which is related to geographical distribution.


In this study, controlled release formulations for reducing environmental impact of pesticides have been produced by encapsulating as a model pesticide carbaryl (Carb) in the alginate beads. The various hydrogel bead formulations were prepared by the ionotropic crosslinking of sodium alginate (NaAlg) with calcium and nickel ions. The surface morphology of prepared beads was characterized with scanning electron microscopy (SEM). SEM confirmed the spherical nature and surface morphology of the particles. Bead characteristics, such as carbaryl entrapment efficiency, particle size, equilibrium swelling degree, and carbaryl release kinetics, were determined. The effects of the bead preparation conditions such as crosslinker concentration and type, carbaryl/sodium alginate (Carb/NaAlg) ratio and percentage of NaAlg on the carbaryl release from the calcium alginate (Ca-Alg) and nickel alginate (Ni-Alg) beads were investigated in distilled water at 25°C. It was observed that carbaryl release from the Ca-Alg beads was slower than that of Ni-Alg beads. The release results indicated that carbaryl release from both of the Ca-Alg and Ni-Alg beads decreases with the increasing crosslinker concentration, Carb/NaAlg ratio and percentage of NaAlg. The highest carbaryl release was found to be 100% for the Ni-Alg beads at 3 days whereas the lowest carbaryl release was found to be 67% for the Ca-Alg beads at 21 days. The swelling measurements of the beads were also in consistent with the carbaryl release results. The carbaryl release from most of the bead formulations followed Case II transport. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007


In Xibaipo,the organization department of CPC central committee participates in the land reform,rectification of the Party,organization construction,standardization of rules,leadership training,assessment,and coordination.All this is greatly helpful with the founding of new China.


An integrated system of vapor-compression chiller and absorption heat pump: Experiment, modeling, and energy and economic evaluation" (2015). Open Access Dissertations. 493.


We have used high-resolution seismic tomography to study the 3-D seismic velocity structure of the mantle or upper mantle beneath several intraplate volcanoes, including Erebus (Gupta et al., 2009), Yellowstone (Tian and Zhao, 2002), Cape Verde (Liu and Zhao, 2014), Tengchong (Lei et al., 2009; Wei et al., 2012), Hainan (Wei et al., 2012), as well as Changbai, Ulleung and Jeju in NE Asia (Zhao et al., 2009; Zhao and Tian, 2013; Wei et al., 2015). Beneath Erebus and Cape Verde, prominent low-velocity (low-V) anomalies are revealed in the upper mantle down to 500-600 km depths, whereas the structure in the lower mantle is not imaged because of the small aperture of the portable arrays deployed around each of the volcanoes. A significant low-V anomaly from the surface down to a depth of about 1000 km is revealed clearly beneath Yellowstone using abundant data recorded by the dense and large-aperture USArray. Beneath the Changbai, Ulleung and Jeju volcanoes, low-V zones are revealed in the crust and upper mantle down to about 400 km depth, whereas a high-velocity (high-V) zone is visible in the mantle transition zone (MTZ), suggesting that these intraplate volcanoes in NE Asia are caused by hot and wet upwelling flows in the big mantle wedge (BMW) above the stagnant Pacific slab in the MTZ. A similar feature is found for the Tengchong volcano in SW China, which may be caused by hot and wet upwelling in the BMW above the subducting Indian plate (or the Burma microplate). Beneath Hainan, a low-V zone exists in the upper mantle, which seems to extend down to at least 1000 km depth. These results indicate a great variety of the mantle structure and origin of the intraplate volcanoes.


We survey the state of research on identity-based cryptography and attribute-based cryptography.We firstly review the basic concepts of identity-based cryptographic schemes in which users' identifier information such as email or IP addresses instead of digital certificates can be used as public key for encryption or signature verification,and subsequently review some important identity-based encryption,signature and signcryption schemes.Then we give our research on Identity-Based Encryption-Signature(IBES) method.We also survey the attribute-based cryptographic schemes in which the identity of user is viewed as a set of descriptive attributes,including some important attribute-based encryption and signature schemes.We subsequently give our research on Attribute-Based Encryption and Identity-Based Signature (ABE-IBS) method.Both methods aim at efficiently improving the security of wireless sensor network.Finally,we propose a few interesting open problems concerning with practical and theoretical aspects of identity-based cryptography and attribute-based cryptography.


Sir, We read with interest the article by Pisoni et al., concerning pruritus in HD patients from an international study (DOPPS) [1]. The authors reported a high prevalence of pruritus in the dialytic population, with a wide variability among different units (10–70%) and countries (36–50%). Although many factors were related to uraemic pruritus, there was no definite conclusion drawn as to the pathogenesis of this symptom, and the large difference in its prevalence among the different countries was not explained by a comprehensive adjustment of many parameters. In our unit, among the 78 patients (age 66 14 years, vintage 70 67 months) on extracorporeal RDT, all undergoing online HDF, 28 patients (36%) had complained of generalized pruritus either continuously or close to the session in some periods while on dialysis. Pruritus disappeared in every patient by stopping antibiotics or aspitin or ticlopidine (n1⁄4 13), by avoiding fixed dressings for fistula needles (n1⁄4 14), or by avoiding woollen cloth (n1⁄4 1). No patient complained of pruritus at the time of this investigation in our unit. In agreement with other authors [2], the present observation suggests that high efficiency and biocompatibility, such as that obtained by online HDF, could decrease dialytic inflammation, and thus the occurrence of pruritus. Moreover, other factors and especially the use of fixed dressings, can cause generalized pruritus beyond the shunt arm. Therefore, in well-dialysed patients, factors other than uraemia or dialysis can play a role in the pathogenesis and persistence of pruritus in RDT patients.


ABSTRACT
 A series of fall surveys and spring resurveys from 2005 to 2010 were examined to determine whether overwinter mortality was a common occurrence in oyster populations from Delaware Bay. Box counts tended to be lower in the spring more often than expected by chance. Occasionally, counts of live oysters also declined. A proportionately larger reduction in dredge efficiency during the winter for boxes compared with live oysters was judged the most likely reason, rather than disarticulation of boxes. Little evidence for overwinter mortality was found; however, reefs in the center of the salinity range exhibited a larger decrease in live oysters than boxes in the spring resurvey. This happenstance provided the only evidence for overwinter mortality that could be distinguished above the countervailing trend provided by the decline in catchability of boxes that frequently occurred. Before ascribing variations in population descriptors during the winter to biological processes, the alternative of an overwinter change in the efficiency of the sampling gear must be excluded.


Purpose
Differently from previous works that focused on the entrepreneur and on his ability to manage social relationships, the purpose of this paper is to investigate the role of business relationships in the different stages of the life cycle of a start-up.

Design/methodology/approach
Since the paper aims to explore startups' evolutionary phenomenon, it adopts a qualitative abductive methodology, presenting an in-depth study of two innovative Italian start-ups. The research is based on two steps. In the first one, the authors collected secondary data from start-ups' reports and documents, financial indicators (when available) and processed them to understand their background. In the second one, the authors conducted ten semi-structured interviews, including face-to-face interviews, phone interviews and video conferences.

Findings
The paper presents a relationship-based life cycle model composed of four different stages, depending on the number and role of relationships developed. Indeed, since the beginning, start-ups adopt a relational approach and their evolution involves the shift from the focus on the entrepreneur to the centrality of a network approach based on interconnected relationships. The entering into a new stage of life cycle depends on relationships, mainly based on connected actors and resources shared and combined. Even if a key role is assumed by technology, the main resource is identified in the knowledge concerning the customer/user's needs that require marketing competencies, human resources, relational capabilities. Thus, the shift from one stage to the next in the start-up's life cycle is possible thanks to a parallel shift from a focus on the activities to a focus on those strategic and heterogeneous actors that ensure activities.

Originality/value
In a traditional perspective, the start-up's life cycle depends on activities, financial resources and revenues, as stated by previous life cycle models. In a different perspective, as depicted in our analysis, the evolution of a start-up depends on the portfolio of their business relationships. The role of business relationships is hence to facilitate the interconnections within specialized key actors, which allow start-ups to access strategic resources. These resources are essential in order to develop the activities that characterize the specific stage of the life cycle.


Virtual reality therapy for mental health complaints has been invented during the last two decades of the past century and has undergone a rather rapid development since then (Emmelkamp & Meyerbröker, 2021). Virtual reality not only has led to highly standardized research environments but also has created a counterpart for clinical practice for the use of exposure in vivo and for practicing social skills in real life. In the beginning, virtual environments were created to treat simple phobias. Virtual environments were built so that an individual could face his fears in virtual reality, and this was the starting point of what has been called virtual reality exposure therapy (VRET). In VRET, it is important that an individual feels present in a virtual environment and that this environment becomes dominant above the real world. This is based on the assumption that an individual is being immersed by the technical components and feels "present" (the feeling of "being there") in the virtual environment (Meyerbröker, 2014). In this virtual environment, the individual will rather respond to events in the virtual environment than to events in the real world. Thus, the consequence of immersion is that an individual feels "present" in the actual virtual environment. While VRET was at first especially used in the treatment of specific phobias and later on in more complex (anxiety) disorders, asking for different interventions than only exposure, the technological development has made more therapeutic aspects possible. It is possible nowadays to navigate through virtual environments and interact with avatars (persons in virtual reality) by speech and gestures, which avatars can react in real time. Virtual reality therapy is also applicable in patients with psychoses (see Rus-Calafell et al., 2018). Virtual reality therapy has potential for (1) cognitive rehabilitation, (2) social skills rehabilitation, and (3) vocational rehabilitation in clinical practice (Schroeder et al., preprint). As the applicability of virtual reality has broadened to more complex mental health disorders, the aim of the current special issue is to provide clinicians with an up-to-date overview on the different areas in which virtual reality already has a clinically relevant additional value. The broadened applicability of virtual reality to other disorders than anxiety disorders has also made different kind of interventions possible. Nowadays, virtual reality in clinical practice is used as an instrument to interact with others, to train certain skills (e.g., social anxiety), to learn how to react properly (e.g., autism), as an assessment tool (e.g., aggressive behavior), and also as a method how to deal with complex interpersonal situations (e.g., aggression management). Virtual reality therapy is applied not only in disorder specific interventions, but transdiagnostic factors such as limited emotion regulation can be targeted with virtual reality as well. We commence this special issue with two disorder specific overviews of (a) the use of virtual reality therapy in anxiety and related disorders (Meyerbröker & Morina, 2021, this issue) and (b) the evidence and the use of virtual reality therapy in the treatment of eating disorders (Riva et al., 2021, this issue). Further, a study about the use of virtual reality in children with aggressive behavior to assess their social information processing capacities (Verhoef et al., 2021, this issue) is included, which provides the reader with an impression on how virtual reality can be used in a quite young population (8–13 years old). We continue the special issue with a study into the therapeutic processes of Avatar Therapy to understand the evolution of avatars' and patients' speech and changes in patient responses in patients with schizophrenia (Beaudoin et al., 2021, this issue). Further, we include a review of virtual reality as a transdiagnostic intervention tool in patients experiencing emotion regulation problems (Colombo et al., 2021, this issue). It shows, that virtual reality therapy is applicable across disorders in a transdiagnostic way. While this prosperous technological development has a great potential, there is as well a pitfall in the use of virtual reality. The Received: 24 May 2021 Accepted: 25 May 2021


This paper presents the design and implementation of a virtual instrumentation system for equipment plastometer and dilatometer to determine the degree of oxidation of coal samples by analyzing its plastic properties. The experimental design and implementation of the sensing, conditioning and acquisition system of the variables that define the plastic properties of the coal supplied by the plastometer and dilatometer and then the design of the virtual instrumentation through the use of the LabVIEW platform with the functions of Capture, pre-processing, storage, visualization and identification of the properties of the coals for their characterization. The electronic instrumentation system implemented was tested using three coal samples previously collected and selected from different coal mines in the Department of Boyacá in Colombia, where satisfactory results were obtained in terms of plasticity and dilatation to determine their application. The implemented prototype applied virtual instrumentation techniques for the measurement of temperature variables and linear displacement of position proportional to the dilation and plasticity of coal using digital signal processing algorithms with benefits such as safety, portability, adaptability and reliability to estimate the rheological properties of the samples coal tested and establish their quality and industrial application. Keywords-Plastic Properties of Coal, Virtual Instrumentation, Digital Signal Processing, Data Acquisition Systems.


Deep learning-based vision is characterized by intricate frameworks that often necessitate a profound understanding, presenting a barrier to newcomers and limiting broad adoption. With many researchers grappling with the constraints of smaller datasets, there's a pronounced reliance on pre-trained neural networks, especially for tasks such as image classification. This reliance is further intensified in niche imaging areas where obtaining vast datasets is challenging. Despite the widespread use of transfer learning as a remedy to the small dataset dilemma, a conspicuous absence of tailored auto-ML solutions persists. Addressing these challenges is"Deep Fast Vision", a python library that streamlines the deep learning process. This tool offers a user-friendly experience, enabling results through a simple nested dictionary definition, helping to democratize deep learning for non-experts. Designed for simplicity and scalability, Deep Fast Vision appears as a bridge, connecting the complexities of existing deep learning frameworks with the needs of a diverse user base.


While determining the ethylene production of plant tissue incubated in 30-ml flasks stoppered with rubber injection caps, we found high and erratic concentrations of the gas. It became obvious that the source of ethylene was not the tissue but the caps which had been autoclaved. To investigate this more fully, caps which had not been used previously were wrapped in aluminium foil and autoclaved at 15 pounds pressure for 20 min. They were then allowed to cool, unwrapped, and immediately fitted to empty flasks which had not been autoclaved; Caps which had not been autoclaved were fitted to flasks at the same time. The vessels were allowed to stand for 16 hr, and the contents of the flasks were assayed for ethylene by gas chromatography (4). Control flasks were found to contain 0.01 ,u/liter ethylene, which was about the same as for normal room air. The ethylene produced by autoclaved caps varied with the cap type and with the batch of caps. Type 11 produced 0.08 ,ul/liter ethylene (10 replicates, two experiments) while one batch of type 2 produced 1.5 ,ul/liter (8 replicates, two experiments) and another batch produced 0.4 Ml/liter (9 replicates, two experiments). Most of the ethylene was evolved in the first 12 hr, but it was still being produced slowly after 24 hr, so that values higher than those given could occur after longer periods of time. Caps were routinely autoclaved for 20 min at 15 pounds pressure, but ethylene production varied with the time of autoclaving and the severity of the conditions. Both types of caps were made from compounds based on natural rubber, and one might have expected a variety of gases to be produced and to increase in proportional amounts in increasingly severe conditions. In fact, ethane, ethylene, propane, and propylene were produced, but, while increases in ethane and ethylene were parallel, increases in propane and propylene were proportionately small. These data are important because it is common practice to autoclave these caps for use in work where sterile conditions are required and because the concentrations of ethylene which accumulated in the flasks are sufficient to cause a variety of effects in plant tissues. For example, 0.02 to 1 Asl/liter can cause morphogenic effects in leaves and stems, fruit ripening, and leaf abscission


A comparison of the risk of intussusception after receipt of monovalent versus pentavalent rotavirus vaccine or versus historical background rates of intussusception found that the monovalent vaccine significantly increases that risk.


Comparison of the amino acid sequences of two families of glycosyl hydrolases reveals that they are related in a region in the central part of the sequences. One of these families (GH family 68) includes levansucrases and the other one (glycosyl hydrolase family 43) includes bifunctional beta-xylosidases and alpha-L-arabinofuranosidases. The similarity of the primary structure of proteins from these families allows us to consider the invariant glutamate residue as a component of their active center. It is shown for the first time that glycosyl hydrolases recognizing different glycofuranoside residues can have a common sequence motif.


In this paper, using the grey correlation analysis method and gravity model, analyzed the tourism development between the impact factors of tourism development in Xinjiang and around the state, according to the analysis of the problems found, some reasonable suggestions on the development of Xinjiang tourism economy.


[ILLUSTRATION OMITTED] HJHP What inspired you to accept the position as executive director of the White House Initiative on Educational Excellence for Hispanics? SEPULVEDA I was involved with the [Obama presidential] campaign from the beginning, so I'm very fortunate that I've known President Barack Obama going back to the early nineties. While involved, I ended up running the Texas [campaign], so when we won, a number of folks asked me to think about coming into the administration, and I said, "sure I'll do it." It was interesting because the president at that time got all of us as state directors on the phone and said, "I need you to do something really hard for me," and we all joked because we thought we just did that. The president said, "I need you to tell all of your staff thanks, and I need you to tell them thanks again, and then I need you to tell them thanks one more time. And then I need you to do something really hard. I need you to tell them I would love for them to work for us in the administration but only if they are qualified to do it" I think it surprised a lot of folks because it was not the old game that if you were involved in the campaign you would automatically get a job, and I think some people got frustrated by that. I was one of the one's saying, "that's why we signed up, this is about doing it different--change." I really appreciated when the president said he wanted people with expertise, and I felt fortunate when they started to talk to me about a number of positions. This position seemed to be the right combination because it would allow me to work with our community nationally on, if not the most important, one of the most important issues for our community. For me it was natural to say of all the [positions] I got offered, this was the one that hit my heart, knowing that our community is at the bottom of all communities in terms of educational attainment. That's why I decided to take this particular position. HJHP What role did your parents play in your educational attainment? SEPULVEDA My father died when I was about a year old, and my mom did not go to college. I was the first one to go to college, but what was interesting to me is that she reminds me of so many of the moms I meet around the country. She didn't even know what college was like but there was no way that I was not going to go to college. I ask my mom, now that I have kids in college, "how did you do it?" And she says to me, "I always decided I wasn't going to tell you what to do but whatever you decided you were interested in, I was going to get 100 percent behind you. The only thing was you had to go to college. That way you will have a better life than we have had." Although she didn't know the system, she helped me figure out what it was like to be at Harvard, and she made sure we had the money to come here. I had to rely on others to help me figure out the system but even though she had no clue what college meant, I was going to go. HJHP Does solving the issue of Latino parental engagement in education solve a major part of the educational attainment problem? SEPULVEDA I wouldn't say it solves a major part of the problem, but it definitely solves a part of the problem. We have to be careful in thinking that just helping parents understand the system is enough. If I understand the system, and the system is not getting me prepared to go to college or for a career or to play a role in the community, it doesn't matter how well I know the system. There is no doubt that parental involvement is critical in helping our parents understand how the system works and helping them understand which level courses their kids should be taking if they want to be a doctor or go into law. That needs to happen, but if we gave 100 percent to just helping parents feel welcomed at the school and completely understanding the system, that wouldn't be enough. …


Constitutional validity of s. 61(4) of Family Law Act 1975 — Jurisdiction of Family Court to entertain s. 61(4) applications — Right of persons other than the surviving parent to make s. 61(4) application for custody


Catalysts based on electroless nickel and bi-metallic nickel-molybdenum nanoparticles were synthesized for the hydrolysis of sodium borohydride for hydrogen generation. The catalysts were synthesized by polymer-stabilized Pd nanoparticle-catalyzation and activation of Al2O3 substrate and electroless Ni or Ni-Mo plating of the substrate for selected time lengths. Catalytic activity of the synthesized catalysts was tested for the hydrolyzation of alkaline-stabilized NaBH4 solution for hydrogen generation. The effects of electroless plating time lengths, temperature and NaBH4 concentration on hydrogen generation rates were analyzed and discussed. Compositional analysis and surface morphology were carried out for nano-metallized Al2O3 using Scanning Electron Micrographs (SEM) and Energy Dispersive X-Ray Microanalysis (EDAX). The as-plated polymer-stabilized electroless nickel catalyst plated for 10 min and unstirred in the hydrolysis reaction exhibited appreciable catalytic activity for hydrolysis of NaBH4. For a zero-order reaction assumption, activation energy of hydrogen generation using the catalyst was estimated at 104.6 kJ/mol. Suggestions are provided for further work needed prior to using the catalyst for portable hydrogen generation from aqueous alkaline-stabilized NaBH4 solution for fuel cells.


We study holographic entanglement entropy for certain logarithmic conformal field theories by making use of their gravity descriptions. The corresponding gravity descriptions are provided by higher-derivative gravity at critical points where the equations of motion degenerate leading to a log gravity. When a central charge of the dual theory is zero, the entanglement entropy has a new divergent term whose coefficient is given by the ``new anomaly'' of the logarithmic conformal field theory.


This brief investigates the positive consensus of fractional-order interval networked systems with the order <inline-formula> <tex-math notation="LaTeX">$\alpha $ </tex-math></inline-formula> meeting <inline-formula> <tex-math notation="LaTeX">$0 < \alpha \leq 1$ </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">$1 < \alpha < 2$ </tex-math></inline-formula>, respectively. Based on the theories of fractional stability and properties of Metzler matrix, by virtue of some rigorous theoretical analyses, the distributed control protocol is proposed and sufficient conditions of positive consensus for fractional-order interval networked systems with <inline-formula> <tex-math notation="LaTeX">$0 < \alpha \leq 1$ </tex-math></inline-formula> are given, which have no connection with the order. What's more, the results can be extended to conditions without using the information of Laplacian matrix with respect to networked topology. Furthermore, sufficient conditions for the systems with <inline-formula> <tex-math notation="LaTeX">$1 < \alpha < 2$ </tex-math></inline-formula> to reach positive consensus are presented in terms of linear matrix inequality. Finally, simulation examples are given to verify the effective of results.


With the continuous development of computer network technology and the large-scale popularization of smart phones, mobile phone palm technology has also ushered in a golden period of rapid development. The development and use of mobile terminals provide a broad and convenient stage for the development of APP technology applications. Based on Android phones, the development and application of mobile phone APP software can effectively improve development efficiency, promote some development activities not to be restricted by time and space, improve the flexibility of the development system, and meet the development needs of the new era. Based on this, this article deeply analyzes the background of developing Android mobile phone APP software on the computer basis, from the aspects of hardware, software and operation, detailed research on software development and application, promotes the popularization of related mobile phone software technology and product promotion, and develops mobile phones for the construction of computers. The APP mode laid the foundation.


In the article suggest the methods of strategic analysis of the milk market in the Russian Federation, the distinguishing features of which are: industry analysis of milk producers take into account a regional aspect and state support, the methodology of analysis of raw milk market associated with the industry analysis and takes into account the macroeconomic indicators, methods of strategic analysis of the market of processed milk varies by a large segment groups.


Selected swe ll wave r e cords fr om Mo nterey , Ca liforn ia a nd the a ss ociated wea the r ma ps we r e ana l yz ed t o de t e rmin~ a t what .s t age in the s torm his t or y th e peak ene r gy i n the svle ll train s vlBS produced. The a ppa r e nt orig i~ of the swe ll, de rived by fr eque nc y -time ana l ys i s of the wave r ec ord s , wa s f ound t o lie within the f e tch de t e r mi ned fr om the wea the r ma ps , and t o occur dur i ng the s t age in the s torm his tory whe n the f e t ch ve l ocity was rapidly de creas ing . The gr ou p ve locity bf the peak ene r gy swe ll was found t o equa l the f e tch ve loci t y a t the time of swe ll or i g in, a condition s uitab l e f or the ge ner a tion of l a r ge wave ene r gy be ca us e of a long e ffe ct iv e wi nd dura ti on. By as s umin g full y ., . ari se n se a s a t the a ppa r e nt swe ll sour ce , an ave rage value of the r a tio of s urface t o geos tr ophic wi nd s peed of 0.77 was ob t a ined . ' Thi s va lue was derived fr om s urfa ce winds obta i ned from the wave da t a and geos tro phic wi nd s obta ine d f rom the weat he r ma ps . These r es ults confirm th e ass umption tha t the peak e ne r gy swe ll wa s ge ne rated in fully ari se n s ea s , a nd that no s hift occ urred in th e pea k swe ll pe riod in shallow wate r off Monter ey .


The present invention is effective to catalyze the asymmetric hydrogenation reaction, the catalyst requires acid activation; effective acidic substance to activate the catalyst; and, in the presence of the acidic substance, acetal, ketals, according to the catalyst composition comprises a buffering compound can form a hemiacetal and / or hemiketal or composition. The present invention also such a catalyst composition for the asymmetric hydrogenation process using; on the use of and such catalyst composition for improving the enantiomeric excess of the desired asymmetric hydrogenation products .