High stator core losses can pose a significant problem in interior permanent-magnet (IPM) machines operating over wide constant-power speed ranges. At lower speeds, the torque ripple can be undesirably large in some IPM machine designs, contributing to acoustic noise and vibration. While previous work has addressed these two problems independently, this paper shows that the conditions for reducing stator core losses during flux-weakening operation, dominated by harmonic eddy-current losses in the stator teeth, can conflict with the conditions for reducing the torque ripple of IPM machines. It is also shown that the resulting design tradeoffs depend on the details of the IPM machine topologies that are under consideration. The appropriate IPM machine topologies that offer more favorable tradeoffs are identified to achieve the best possible compromise of high-speed stator core losses and torque ripple characteristics.


We present an image coding scheme based on the properties of the early stages of the human visual system. The image signal is decomposed via even and odd symmetric frequency and orientation selective bandpass filters in analogy to the quadrature phase simple cell pairs in the visual cortex. The resulting analytic signal is transformed into a local amplitude and local phase representation in order to achieve a better match to its signal statistics. Both intra filter dependencies of the analytic signal and inter filter dependencies between different orientation filters are exploited by a suitable vector quantization scheme. Inter orientation filter dependencies are demonstrated by means of a statistical evaluation of the multidimensional probability density function. The results can be seen as an empirical confirmation of the suitability of vector quantization in subband coding. Instead of generating a code book by use of an conventional designalgorithm we suggest a feature specific partitioning of the multidimensional signal space matched to the properties of human vision. Using this coding scheme satisfactory image quality can be obtained with about 0. 78 bit/pixel.


This paper examines the effects of differentiated urban transport policies in a real world scenario of food retailers in the city of Berlin. A microscopic model is constructed which maps several tactical and operational logistics decisions. It is an optimization problem for individual firms which is solved heuristically considering time-of-day dependent transport costs. The impacts of urban freight transport policies that differentiate between area, time-of-day and vehicle type are discussed and evaluated by the variations of distribution costs and environmental indicators. The model shows that policy measures restricted to a certain area and vehicle-types, can have significant impact on the whole area under examination.


This paper presents a new checkpointing algorithm that guarantees the semantics of reliable communication channels despite the crash and recovery of processes. This algorithm requires O(n+m) communication messages, where n is the number of participating processes, and m is the number of "late" messages. The algorithm is nonblocking, requires minimal message logging, and has minimal stable storage requirements. This algorithm is also scalable, simple transparent to the user, and facilitates fast recovery. By introducing suitable delay in the checkpointing process, the parameter m can be made small. We also describe a variant of the algorithm that requires only O(n) messages, at a cost of O(n) additional storage for each process.


The utility model relates to a hot-furnace bar changing device of a fiber drawing furnace, which is characterized by comprising an isolation sleeve. A connection plate is arranged at the lower end of the isolation sleeve and connected with a top cover of a drawing furnace; a light ring type shutter is installed at the upper end of the isolation sleeve; an air blowing pipe is arranged in the upper middle portion or the middle of the isolation sleeve along a peripheral direction; an air blowing opening of the air blowing pipe is arranged inwards; and the air blowing pipe is communicated with a pressure nitrogen source. The isolation sleeve is in a cylinder shape, a hollow sealed jacket is arranged along the wall of the cylinder; and the upper portion and the lower portion of the hollow sealed jacket are respectively connected with a water inlet pipe and a water outlet pipe. The hot-furnace bar changing device has the advantages of 1, capabilities of effectively reducing entering of air in exchanging process of pre-manufactured bars, and prolonging service life of drawing furnace graphite assemblies, and 2 capabilities of performing bar exchanging operation without furnace stoppage when the drawing furnace is at higher temperature ranging from 1200 DEG C to 1500 DEG C, effectively reducing stopping time of the drawing furnace caused by bar exchanging in fiber drawing process, improving drawing effect, and improving use efficiency of the device.


The article investigates the methodological debates that took place during the institutionalization process of the Italian Political Science in the late nineteenth and early twentieth centuries. Gaetano Mosca and Vilfredo Pareto aspired for a scientific knowledge of the policy to be built in correspondence to natural sciences practices. Mosca strongly advocated for a historical method that would find the psychological forces inside the institutions that could guarantee the regularity of the political phenomena. Pareto advocated a logical-experimental method in which abstract propositions (principles) condense the common features of many facts apprehended through experience. Both projects, however, did not distinguish precisely observation, experiment and experience. For this reason, their methodologies were not able to go beyond the hegemonic political study techniques of their time.


The purpose of this paper is to examine the current Customs broker service portfolio and the relevance of each service portfolio their business today and what type of business opportunities are they looking for int he future under the Trade Supply Chain Security. This paper consist of four main chapter. Chapter Ⅱ reviews WCO and International Trade Supply Chain Security and roles for Customs brokers in major countries. Chapter ill describes currents business environment and service offerings, potential change drivers- Supply chain security and Information communication technologies, future trend and roles for customs brokers' business. Finally, Chapter N summarizes the results of the study and suggests implications.


OBJECTIVE To investigate into the effect of different combinations of acupuncture points on the anti-oxidation system of mice with S180 ascitic tumor receiving chemotherapy with CTX. METHOD 90 Kunming mice were divided randomly into 9 groups and injected with S180 tumor strains. Chemotherapy with CTX was given and acupuncture with warming needle method at Zusanli, Mingmen and Dazhui and moxibustion were also given. The observation indexes included serum MDA, GSH-PX and SOD. RESULT Acupuncture and moxibustion have good protecting effect on serum MDA and SOD, with marked difference between the treatment groups and the control groups ( P 0.01). The contents of serum MDA in the treatment groups were also greatly lower than those in the experimental and control groups ( P 0.01). CONCLUSION Marked difference exists between different combinations of points in their actions upon the anti-oxidation system of tumor-bearing mice receiving CTX chemotherapy.


Abstract The title reaction proceeds through the formation of an intermediate [CoIII W... N3]6 formed between [ComIIIW]5- and N3- and not between [CoIIIW]5 and HN3. The absorbance measurements of the intermediate at various [HN3] yield an equilibrium constant Κ = 0.012 ± 0.001 at 35° C which compares well with the value 0.011 obtained at that temperature from the kinetics data. The reaction is first-order with respect to [ComIIIW]5- and HN3. The pH dependence of kobs, the pseudo-first-order rate constant ([HN3] > [CoIIlW]5-), is consistent with the linearity of the plots between kobs-1 and [H+] with intercepts on the rate ordinate. The inverse correlation between kobs and [H+] is traced to the equilibrium HN3 ⇄ N-3 + H+ followed by [CoIIIW]5 + N3 ⇄ [CoIIIW... N3]6 andnot through the equilibria [CoIIlW]5 + HN3 ⇄ [ColIIW ...N3]6- + H+. The high reactivity of the N-3 ion is traced to the presence of an unshared pair of electrons as in the case of NH2OH and N2H4 which seems to imply an inner-sphere mechanism with the substrate binding to the oxidant via this pair of electrons. However, in view of the well-protected nature of the central CoIII atom in [ColIIW]5- ion there is difficulty in visualising the coordination of the substrate with the Co1" ion. That the electron transfer is outer-sphere is substantiated by excellent agreement between the experimental rate of electron-transfer, 0.305 dm3 mol-1 s-1 , and the one (0.339 dm3 mol-1 s-1) calculated by the application of Marcus equations.


Classical Contract-Net protocol among the multi-Agent bidding can realize the cooperation of open heterogeneous environment. But MAS (Multiple Agent System) is a typical complex system. MAS's open, distributed and dynamic characteristics make the MAS environment filled with a lot of indeterminate factors, lead to surge in network traffic and negotiation deadlock. To solve these problems, this paper introduces the trust level domain and reputation mechanism to establish trust and reputation of the Contract-Net model. The model based on the history of cooperation experience in multi-Agent can effectively reduce network traffic, improve the efficiency and cooperation real-time of MAS.


This study introduces a hierarchical Bayesian approach, dubbed hierarchical generalization modeling (HGM), to assessing a model's generalizability between experimental tasks. The basic idea of HGM is to use a hierarchical modeling structure to evaluate the extent to which a model explains data observed in different experimental tasks and conditions that share some common underlying processes. The HGM approach represents an extension of the current methods of model selection, such as the Akaike Information Criterion and the Bayesian Information Criterion, that assess the generalizability of a model within a given experimental setting. We demonstrate the soundness and feasibility of HGM for models of risky decision making with human data from decision-from-description and decision-from-experience experiments, and also in simulations with artificial data.


This article is an introduction to the Petersson trace formula and Kuznetsov trace formula, both of which are now important, standard techniques in analytic number theory. To illustrate their applications to modular forms, we will explain their role in a proof of subconvexity bounds for Rankin-Selberg L-functions L(s, f⊗ g) on the critical line σ = 1/2, where here and throughout, we write s = σ + it for s ∈ C. Here f is a cusp form whose weight (if f is holomorphic) or Laplace eigenvalue (if f is nonholomorphic) tends to∞, while g is a fixed cusp form. There are nine sections:


A novel fusion fault diagnosis method based on IRN was presented.It adopts wavelet transform as feature extractor and IRN network as classifier respectively.Results of simulation testify that this proposed method owns good fault-tolerance and anti-jamming ability.This method is commendably practical and feasible to use.


This study investigates the determinants of corporate performance and evaluates whether ISO 9000 registration impacts corporate performance in a sample of Malaysian listed companies. A performance evaluation model was developed on the basis of four predictor variables that include return on sales (ROS), lender security, free cash flow and economic value added (EVA). The results indicate that the ROS and EVA do determine the performance of the Malaysian listed companies. We also find association between ISO 9000 registration and financial performance in the sampled companies.


Catalytic hydrogenation of several 3-acyl-4-[2-(indolyl)carbonylmethyl]-5-(methoxycarbonyl)-1,4-dihydropyridines 4 gives chemoselectively the corresponding 1,2,3,4-tetrahydropyridyl esters 5, which have been elaborated into the tetracyclic 2,3-diacylindole system 6 of oxosilicine alkaloids. Barton decarboxylation of the N-benzyl derivative 6e, followed by debenzylation and subsequent stereoselective reduction of the 5,16-double bond gives (±)-6-oxo-16-episilicine. This compound is converted into (±)-6-oxosilicine by base-catalyzed epimerization.


The theory of the superconductor–insulator–superconductor (SIS) multilayer structure for application in superconducting accelerating cavities is reviewed. The theoretical field limit, optimum layer thicknesses and material combination, and surface resistance are discussed for the SIS structure and are also reviewed for the superconductor–superconductor bilayer structure.


The tomoscopic laser detection device according to the invention comprises means (1, 2) to illuminate a target (3) at a wavelength that is unusual for a laser source, means (4) to obtain a temporal gate on the wave that is back-scattered or partially reflected by the target (3) following the laser illumination and means (5) to convert the unusual wavelength into a wavelength appropriate for an image sensor (6), enabling discretion of detection to be ensured. Application to reconnaissance, "de-camouflage", 3D navigation.


Chapter 1 1. The Theological Category-Formations of Rabbinic Midrash [1]: God and Man, God and Israel Part 1 Preface Chapter 2 2. The Theological Category Formations of Rabbinic Midrash [2]: God, Israel, and the Nations Part 2 Introduction Chapter 3 3. The Theological Category-Formations of Rabbinic Midrash [3]: God's Justice and God's Misery Part 3 Part One. The Common Theology of Rabbinic Midrash Chapter 4 4. The Theological Category-Formations of Rabbinic Midrash [4]: God's Judgment, Israel's Repentance and Atonement, God's Remorse, Israel's Consolation Chapter 5 5. The Theological Category-Formations of Rabbinic Midrash [5]: Restoration, The End of Days Part 5 Part Three. Midrash-Compilations without Conventional Theological Category-Formations Chapter 6 6. Special Cases: Theological Category-Formations Particular to a Single Document Part 9 Part Two. The Special Cases and General Conceptions Chapter 11 7. The Implicit Theological Foundations of Sifra Chapter 13 8. Midrash Without Theology: Sifre to Numbers Part 14 Part Four: Rabbinic Judaism: The Theological Construction Chapter 15 9. The Place of the Rabbinic Midrash-Compilations in the Encompassing


The division of Arts and Science in China originated from late Qing dynasty, when the Education Department submitted a memorial to the throne Proposal of Dividing the School Curriculum into Arts and Science in 1909. Then the two disciplines went through combinations and separations repeatedly over the past 100 years. This paper will investigate the separated education system's evolution history in late Qing dynasty and its resulting drawbacks ever since from a historical perspective. We can not only draw some lessons from the investigation, but also acquire a clearer understanding of the division of Arts and Science subjects when facing the same or contradicting problems nowadays.


It can be argued that the textiles and clothing industry does not neatly fit into either a lean or agile paradigm, instead, it is a combination of the two, driven by low margins and volatility of demand. A number of authors have indicated that these two concepts alone seem incomplete so that now the global approach is towards a hybrid supply chain model combining both lean and agile concepts. Apparel Industry possesses the twain lean and agile features independently and these concepts have been established to a greater extent. As cases of pure leanness and agility can seldom be found in real-world problems, considering both strategies can be beneficial. Analyzing the characteristics, trends, and relationships within an organization's internal and external environment as well as considering the impact of the new strategy on overall supply chain performance is much important when developing a supply chain model. This paper focuses on developing a framework to integrate Lean and Agile Concepts for improving supply chain performance in fashion garment manufacturing. A structured literature review is carried out in stages: identifying the relevant literature, structuring the review and developing a model to guide future research.


Pointing to the persistence in the Romantic Enlightenment of even the minor pagan gods, the essay focuses on the function of the genius loci in Shelley's 'Mont Blanc', both its subtle presence and its ghostly, quasi-theophanic intervention at the end of stanza 2. Shelley uses features of the 'Great Ode' to express his own type of religious feeling in the face of the sublime of Nature, while making of Mt Blanc a counter-Sinai. Though close to trance, he rejects the traditional response of abjection and affirms 'my own, my human mind' in a poem that is a remarkable instance of the transformed minor genre of the nature inscription and deepens our understanding of his atheism as a refusal to name the unknown power he acknowledges. Why did even the minor Classical deities retain for so long their hold on the god-making process, the theopoesis of European poetry? Why would the great Romantic poets not allow these mythical figures—often just decorative names—to 'slumber, and die in autumn umber', as Wallace Stevens mock ingly suggested more than a century later in 'Notes toward a Supreme Fiction'? Paganism permitted a deus multitude>, also in the form of a huge and variable mesocosm of semi-divine beings. 'The death of one god is the death of all' Stevens intoned. But that proved not to be the case. The theme itself of the death of God, or the twilight of the gods, attracted, in all its pathos, Continental European poetry. Not only were 'Ossian' and the non-Classical 'Northern Antiquities' very influential, not only did Shelley's Prometheus Unbound rewrite a Greek tragedy dealing exclusively with gods and lesser divinities as its on-stage protagonists, while Keats in England took up the twilight of the gods in his two Hyperion fragments,1 but the fanciful mesocosm I have men tioned, joined to folklore, gained a new and multiple infusion of life.2 I am initially interested here in the survival of this mesocosm, or lesser species of supernatural figures. By the time of the Romantic Enlightenment an airy, earthy, fiery, watery pantheon (or pandemonium) of 'middle spirits' was readily available, free of any but poetic censure, free also to be newly Literature & Theology © The Author 2010. Published by Oxford University Press 2010; all rights reserved. For Permissions, please email: firstname.lastname@example.com I The Author 2010. This content downloaded from 22.214.171.124 on Fri, 02 Sep 2016 06:00:08 UTC All use subject to http://about.jstor.org/terms GODS, GHOSTS, AND SHELLEY'S 'ATHEOS' 5 minted or augmented. Middle spirits are multitudinous minor deities, as immortal or mortal as their function; and that depends on the element or person with which they form a bond. Ghostly agents, they can be likened to good or bad angels, whether of Oriental or Classical/Pagan origin. They are beings often with fixed character or mission, except we may not always be certain about their trust-worthiness, provenance, shape, sex, or even longev ity. Named the 'machinery' for their literary usefulness3 or perhaps after the notion of deus ex machina, they include the elemental nature spirits of Coleridge's 'Ancient Mariner' as well as post-Spenserian giants and faeries exploited, for example, by Blake, but also largely dismissed by him at the end of Vala's 'Night the Ninth'. Middle spirits are often merely inflated allegorical personifications. They tend to be as rampant as cherubs or cupids, from medieval Romances to Pope's 'Rape of the Lock'. They were contemptuously denounced by Coleridge as 'godkins and godesslings'. Yet, we cannot bad-mouth them when they are used as aptly as in Shelley's Adonais, where Keats's orphaned dreams and thoughts are personified in pastoral-elegiac terms as a flock of 'Splendours, and Glooms, and glimmering Incarnations' mourning their dead poet.4 And while Coleridge's verse, like Wordsworth's, usually shuns such leftover daimons, especially in their decorative neoclassical and vers de societe usage—Wordsworth, indeed, formally banished them (for a time) as belong ing to an otiose 'Poetic Diction',5—the 'Ancient Mariner' retrieves something of their deeply human, sensory and imaginative rationale. So, starting with the epigraph quoting Thomas Bumet, that there are more invisible than visible beings in the universe, to viewing the Albatross as the emissary of the Polar Spirit (a guardian genius loci), and creating an uncanny sense of the danger of trespass in this poem's heterocosm—from such effects a polytheistic crime and punishment nightmare unfurls in 'The Ancient Mariner'. The crime committed is, basically, against the genius loci, its hos pitality. The fit punishment, therefore, is homelessness: eternal, restless wandering. One mythic poetic notion that outlives the Christian expurgation of pagan ism, is 'genius' as a daimon bonding with person or place, and marking specific spots as a source of inspiration or revelation. Such genii were a kind of soul, a special sensitivity or consciousness assigned, possibly via the stars, to inani mate as well as animate beings. Genii were also associated with the marriage bed—with fertility—and probably through that with creativity. Indeed, the 'parting Genius', which Milton (adapting Plutarch) depicted lamenting as it fled its haunts on the morning of Christ's nativity, never really This content downloaded from 184.108.40.206 on Fri, 02 Sep 2016 06:00:08 UTC All use subject to http://about.jstor.org/terms


The Appreciative Inquiry (AI) model is based on the assumption that the questions we ask will tend to focus our attention in a particular direction. Instead of asking "What is the problem?" which AI argues maintains a basis of deficiency, AI takes the alternative approach. As a self defined asset-based approach, AI starts with the belief that every organization, and every person in that organization, has positive aspects that can be built upon. It asks questions like "What is working well?", "What is good about what you are currently doing? Cooperrider, Whitney, and Stravos (2008) explain that the outcome of an AI initiative is a long-term positive change in the organization. They assert that AI is important because it works to bring the whole organization together to build upon its positive core. The AI strategic framework is ideal for leaders within the higher educational arena called upon to assess the value of business school education. One of the most common areas utilized to assess the value of a business school education is student learning. The focus of the present research is to discuss current methods and challenges associated with assessing student learning within business school education. AI will be highlighted as an alternative method for assessing the value of the business school education reflected through student learning.


Abstract : This report lays a logical foundation on which deficiencies of dynamical prediction models can be defined and dealt with on a rational basis. Measures of the quality of performance of dynamical prediction models are suggested, and a procedure with which deficiencies of the models can be diagnosed is proposed. A sample study is used to illustrate the use of the proposed procedure, and the results of the study are presented. (Author)


An environment was developed for solving the problem of selecting a proper software reliability model for a given set of software failures. The idea behind the environment developed in this dissertation was to liken a collected set of software failure data to a previous one that proved to fit well with a specified software reliability model. Software failures were assumed to have a two-Parameter exponential distribution with unequal type II censoring. A test criterion was derived for testing the equality of software failure data sets using the Maximum Likelihood Ratio criterion. The exact distribution of the test criterion was derived. An asymptotic approximation was also obtained and was found to be very close to the exact distribution when the number of failures were more than twenty. Software failure data available from "Data and Analysis Center for Software (DACS)" were used as the initial group of software failure sets. The environment was then applied, for testing the equality of several software failure sets.


In anoxic methanogenic sediments organic matter is degraded to CH4 and CO2 via intermediary metabolites. When CH4 production in slurries of littoral sediment was inhibited by chloroform, acetate accumulated with a rate (2.26 μM h−1) similar to the turnover rate (2.09 μM h−1) of [2−14C]acetate. Addition of chloroform resulted also in accumulation of propionate > 2-propanol > caproate > valerate > H2. Accumulation of H2 was small but sufficient to thermodynamically inhibit consumption of caproate and valerate by H+-reducing bacteria. Consumption stopped when the available Gibbs free energy had increased from about −16 to about −9 kJ mol−1 H2 produced. 2-Propanol increased probably mainly because of the accumulation of acetate with the available δG increasing from about −13 to −3 kJ mol−1 of 2-propanol consumed. Propionate accumulation, however, could not be explained by thermodynamic inhibition of propionate consumption since the Gibbs free energy of this reaction was generally very low (δG ≈ −3 kJ mol−1). Bacterial enrichment cultures on cellulose resulted in the production of similar metabolites as observed during the accumulation experiments. Assuming that propionat, 2-propanol, caproate and valerate were converted via acetate and H2 to CH4, their accumulation rates plus that of acetate accounted for 134% of the rate of CH4 production. Carbon flow through acetate accounted for 80–87% of the total carbon flow to CH4. This relatively high percentage may be due to the relative importance of either homoacetogenesis or of acetate-rich organic matter (e.g., chitin) in littoral sediment of Lake Constance.


This paper is concerned with the finite time identification performance of an n dimensional discrete-time Multiple-Input Multiple-Output (MIMO) Linear Time-Invariant system, with p inputs and m outputs. We prove that the widely-used Ho-Kalman algorithm and Multivariable Output Error State Space (MOESP) algorithm are ill-conditioned for MIMO system when n/m or n/p is large. Moreover, by analyzing the Cramer-Rao bound, we derive a fundamental limit for identifying the real and stable (or marginally stable) poles of MIMO system and prove that the sample complexity for any unbiased pole estimation algorithm to reach a certain level of accuracy explodes superpolynomially with respect to n/(pm). Numerical results are provided to illustrate the ill-conditionedness of Ho-Kalman algorithm and MOESP algorithm as well as the fundamental limit on identification.


Three 10 cm-diameter skin fields on shoulder, chest, and ham of 24 swine were irradiated with acute single exposures of 1700, 2300, and 2700 R. The animals were anesthetized, biopsied, and sacrificed at intervals from 1 to 70 days following irradiation. The observed histologic changes comprised a degenerative and a regenerative phase. The degenerative phase was characterized by progressive cell loss (similar for all fields), an increase in nuclear volume, and a decrease in mitotic index. The regenerative phase was characterized by the appearance of discrete islands of normal-appearing cells. Three types of islands were designated as small, large, and giant based on chord length. These regeneratiang islands increased progressively in size until the field was reepithelialized; the mitotic index was as high as 6% with a tritiated thymidine labeling index between 30 and 70%. The cell cycle time was estimated to be 15 h. The number of islands at 17 to 28 days following irradiation was dose-dependent with D/sub 0/ of 272 R for small islands, 568 R for large, 1620 R for giant islands and 337 R for the combined data. Reepithelialization was attributed to proliferation of cells in giant islands. Cells from small islands contributed little.


INTRODUCTION: The results obtained from the analysis of age dynamics are insufficient for development a program of reducing morbidity and, ultimately, mortality, since a need of medical care already indicates a problem; so prevention and screening programs should surpass the emergence of these problems. AIM: To analyze the age dynamics of the need for outpatient medical care for conditions that determine the basic value of the need in women with diseases of the circulatory system. MATERIALS AND METHODS: We used data on 780,000 visits during one year to medical organizations that provide medical care on an outpatient basis. We studied the probability of an episode and the dynamics of the frequency of episodes depending on age in six five-year age groups: 31 to 35 years, 36 to 40 years, 41 to 45 years, 46 to 50 years, 51 to 55 years, and 56 to 60 years. The dynamics of the frequency of episodes was modeled by a mathematical function with the largest value of the approximation coefficient. The dynamics of the frequency of episodes was modeled by a mathematical function with the largest value of the approximation coefficient. RESULTS: The dynamics of the need for outpatient medical care for hypertensive diseases [Diseases characterized by high blood pressure] (I10 – I15), ischemic heart diseases (I20 – I25) and vascular diseases of the brain (I60 – I69) is characterized by an increasing trend in demand indicators throughout the studied age period. The greatest increase in indicators is observed in the age groups of 31–40 years for ischemic heart diseases and vascular diseases of the brain and 41–50 years for hypertensive conditions. The greatest increase in demand is observed for coronary heart diseases (I20 – I25). The total amount of resources required increases more than 350 times over the 30-year age period, despite the stable value of the average duration of treatment. The increase in the total amount of resources required for vascular diseases of the brain is 30 times. The lowest growth gradient is registered in relation to hypertensive conditions (10-fold growth). As a critical age period, it is most appropriate to consider the age of a woman under 35 years. CONCLUSION: Mathematical modeling is optimally performed using power functions for hypertensive conditions and vascular diseases of the brain and exponential functions for ischemic heart diseases. All the proposed models are characterized by high approximation coefficients.


Miss J D aged 18. Unemployed. History: Pink urine was noticed when she was two days old but this cleared. It recurred at 4 months old, when porphyrins were demonstrated. The infant was readmitted to hospital when aged 51 months with a himolytic anemia: Hb 39%, 5 % of red cells showed red fluorescence in ultraviolet light. Since there was no improvement with transfusion, she underwent splenectomy, with a subsequent rise in platelets and h2emoglobin remaining for a time at 10 g/100 ml. The large spleen, weighing 95 gm, showed an intense fluorescence under ultraviolet light. Her teeth, which erupted at the usual time, had a pinkishbrown discoloration and fluoresced in ultraviolet light. Hypertrichosis developed on forehead, sides of face, arms and legs in the next few months. In May 1956, her first summer, blisters appeared on areas exposed to light and since that time she has remained extremelyElight sensitive. All attempts to alleviate the light damage have failed until recently. Screening creams, oral chloroquine and adenosine monophosphate internally appeared to have no beneficial effect. She has continued to suffer repeated hmmolytic crises and Hb has been 4-12, averaging 7.5 g/100 ml. She has been transfused three to five times annually though the intervals between transfusions have somewhat lengthened in recent years. When aged 5 she began to show scarring of the scalp with permanent hair loss, scarring of face and hands and, from the age of 12 onwards, she has become more and more disabled by sclerodermatous thickening on the hands. She led a completely withdrawn existence until May 1973 when, after starting :-carotene 25 mg t.d.s., she found she could leave her home in daylight without suffering blister formation. It was hoped that the heemolysis might also benefit but she recently required a transfusion and no alteration in photohmmolysis has been detected. Objective tests with ultraviolet light have not been carried out. Family history: Mother and father well. Two brothers aged 16 and 8 and twin sisters aged 5 all well. No history of light sensitivity or porphyria. On examination: Extensive scars and sclerodermatous changes in scalp and face and hands. Those teeth which are not capped show pink discoloration. Liver enlarged to 6 cm. Investigations: There is constant evidence of haemolysis with presence of nucleated red cells and reticulocytosis of6-10 %. Red cell porphyrins:


The noise produced on the ground by a jet aircraft flying overhead is a signal whose amplitude varies by as much as 40 dB and whose duration may vary from 10 to 30 sec or more. Recent specifications for aircraft noise require a 12‐oct band frequency analysis over the audible frequency range of this signal at each 0.5 sec interval of the time pattern. We describe a hybrid data analysis system used for this purpose which consists of a Hewlett‐Packard model 8054‐A Real‐Time Spectrum Analyzer controlled by a DEC PDP‐8 computer using a conversational language in the control program. The effect of analyzer time constants and various scanning rates on data repeatability and reliability are presented. These results are compared to those obtained with the more commonly used filter‐graphic level recorder combination.


This new column will give you the tools you need to diagnose and solve your office's problems. First up: Are you a high performer?


Received 6th January, 2019 Received in revised form 15th February, 2019 Accepted 12th March, 2019 Published online 28th April, 2019 The treatment of myocardial ischemia-reperfusion injury is the focus and difficulty of researchers and clinicians. With the aging of the population, the incidence of myocardial infarction is increasing year by year. At the same time of modern medical treatment of myocardial infarction, scholars pay more and more attention to the role of traditional Chinese medicine in the treatment of myocardial ischemia-reperfusion injury in order to greatly reduce the harm of myocardial ischemia-reperfusion injury. Among them, as an important part of traditional Chinese medicine, the efficacy of ethnic medicine in the treatment of myocardial ischemia-reperfusion injury has been affirmed by many people. In order to fully explore the medicinal value of ethnic medicine in the treatment of myocardial ischemia-reperfusion injury, the author reviews the recent research on ethnic medicine in myocardial ischemia-reperfusion injury, in order to provide reference for clinicians and researchers to do further research.


This paper outlines how an aerial telecommunications network can optimally meet the stringent needs of emergency relief and recovery operations. We propose a novel architecture, made of an integrated and highly dynamic multi-purpose aerial telecommunications infrastructure that can be contextually extended with fast-deploying high or low altitude platforms. In particular, we analyze the interest and challenges of adapting core concepts from substitution networks and controlled mobility mechanisms, so that a base network can be seamlessly augmented, both in terms of capacity and functions. We give an estimation of the emergency traffic supported by the lower altitude platforms in an example scenario and discuss the challenges posed by this architecture, notably in terms of disaster resilience and ability to efficiently provide sustained first responder communications.


Anaesthesia in children with upper respiratory tract infection (URTI) remains a daily challenge for the anaesthesiologist. In the recent APRICOT study, the overall incidence of peri-operative respiratory complications (PRC) was estimated at 3% while it occurred in up to 30% of children with ongoing or recent URTI symptoms. Similarly to what is reported in asthmatic patients, children with recent URTI develop airway sensitivity as a consequence of airway inflammation. Thus, we tested the ability of nebulised corticosteroids to prevent peri-operative oxygen desaturation in children with recent URTI. Corticosteroids have been employed for the prevention of PRC in children with URTI.


Iron deficiency anemia is a leading cause of death as well as health problems in the mother and fetus. Impacts that can be caused include abortion, stunted fetal growth, preterm labor, antepartum bleeding, retention of the placenta, and preterm labor. Important information about reducing anemia which can reduce the incidence. One effort that can be done is with health education. The purpose of this study was to determine the effectiveness of health education on increasing knowledge in anemia of iron deficiency anemia in pregnant women. This type of research is an experimental study with the design of one group pre-test post-test. The sampling technique in this study is the quota sampling of 50 respondents. Data collection was carried out using questionnaire sheets and analyzing data using the Wilcoxon sign test. The results showed that health counseling was effective to increase the knowledge of the respondents (0,000),with the difference between pre-test and post-test, which was 3.02. It is expected for health workers to increase health education related to anemia in pregnant women, so they have good knowledge to avoid this.


This paper presents a position tracking controller for an induction motor driving a robotic load. Using nonlinear models of the induction motor and a nonlinear observer, a focal exponential stability (ES) result for motor position tracking error is obtained. The control only requires measurements of rotor position and stator currents while utilizing exact knowledge of the system parameters. Simulation results are given to show the effectiveness of the proposed controller.<<ETX>>


I have already communicated to the Royal Society the fact that the introduction of an alkali, as the carbonate of soda, into the circulation, prevents the production of diabetes in an animal after an operation on the sympathetic nerve that otherwise occasions it. On excising, for example, the superior cervical ganglia, or dividing the ascending branches of the superior thoracic ganglia, diabetes is an almost constant result in the dog. Now, I have a record of ten experiments, in which, before attacking the superior cervical ganglia, 200 grains, or nearly so, of the crystallized carbonate of soda dissolved in a small quantity of water, were introduced into the general circulation through the jugular vein.


From three dimensions of social capital (structural, cognitive, relational) its effects in industry-university-research collaboration are explored as benefits of information, effective communication and building trust base, which are helpful to accumulate intellectual capital of firms. A case study is employed to illustrate that social capital could promote intellectual one. On the basis of the link between social capital and the main problems in I-U-R collaboration, it is proposed that fostering social capital of firms should be the key for further development of I-U-R cooperation.


Nowadays, phishing poses a big threat to people's daily network environment. By phishing, attackers obtain the network users private information by inducing them to open illegal websites. Due to the active learning ability and preferable classifying ability for many datasets, BP neural network is an important heuristic machine learning method in phishing websites detection and prevention. However, improper selection of initial parameters, such as the initial weight and threshold, will induce the BP neural network into local minimum and slow learning convergence. Aiming at these problems, this paper proposes DF.GWO-BPNN, an effective phishing website detection model based on the improved BP neural network and dual feature evaluation mechanism. Under this model, the grey wolf algorithm is firstly used to optimize the BP neural network to reasonably select initial parameters. Then, the dual feature mechanism is used to evaluate the results of the improved BP neural network. By the dual feature evaluation mechanism, the accuracy of phishing website recognition is improved. Meanwhile, the black and white list is used to improve the efficiency of the proposed model. The DF.GWO-BPNN model is compared with some existing phishing website detection models. The experimental results have demonstrated that our model is accurate and strong adaptability.


Welfare aid in the USA groups close to means-teste programs and all targeted on categories of people, and mainly on households with children. The majority of these benefits which make up "Welfare" were subject during the 1990's to various reforms which, by reinforcing the principle of counterpart and by favouring a return to employment, also modified the functions of welfare aid. In addition, the main reform of welfare aid which occurred in 1996, setting up a system of "Workfare" at the federal level, accentuated the autonomy of the States in managing and defining such programmes. Any analysis of this reform and its applications is generally made at the national level, but important differences appear when one targets study onto the welfare aid policies followed by the federal States. This is the viewpoint taken by this article which above all seeks to describe the disparities in the institutional devices set up by the federal States, their different strategies regarding welfare policy, and their impact on poverty levels. The analysis by case types allows one to illustrate the variations observed between States in more concrete terms.


The ZnO thin film was deposited on n-Si (100) by sol-gel and spin coating technique. Pd/ZnO/n-Si/Ti/A1 Schottky contact was fabricated by the thermal evaporation method using shadow mask technique. The ZnO thin film was annealed in Ar (argon) atmosphere at 450°C to enhance the structural and surface morphology. The structural and surface morphology of prepared ZnO thin film were characterized by the XRD and SEM and it was found that the thin film was polycrystalline in nature with homogeneous surface. The I-V characteristics of the device were analyzed by the semiconductor parameter analyzer. The semiconductor parameters were determined at different operating temperature in air atmosphere.


Earthquake is one of the inevitable natural disasters.Every country develops and implements different earthquake emergency response measures according to its own national conditions.Systems for dealing with earthquake disaster are relatively complete for developed and earthquake-prone countries.Based on the analysis of status quo in the US and Japan,this paper pointed out the problems existed in the emergency management in China and proposed scientific,reasonable and effective recommendations on the management,organization and legal systems.It is helpful to the improvement of China's earthquake disaster emergency management system.


Taking sub marketization as background, and rationality, economy and reliability as targets, and the technical management of the project of diverting water from Yangtze River to North Jiangsu as a practical sample, the technical management models and methods for large step pumping stations in South to North Water Transfer Project were discussed and analyzed in viewpoints of management system, operation management, daily management, maintenance and overhaul. These research results is helpful to improving water transfer reliability, reducing cost and promoting sustainable development of the project.


The biblical name of God that appears more often in the Sacred Text is LORD, or, as some versions show, Jehovah. Much has been discussed about the pronunciation of the original Hebrew YHWH. It would be really Jehovah? Since the names in the Bible are full of meaning, what the name of four letters, also called Tetragrammaton, mean? It would reveal the identity of the God of the Israelites? This article aims to answer these questions.


At present, with the continuous improvement of social and economic level, people's living and income level also show steady growth, so most families also buy vehicles to facilitate daily work and travel. However, due to excessive traffic trunk lines, the congestion of urban road sections is becoming more and more serious. As a powerful means to solve the phenomenon of urban congestion, it is necessary for public security organs and other departments to strengthen the cognition and thinking of anti-terrorist security, through the actual situation of urban traffic track, formulate reasonable and effective anti-terrorist plan to ensure traffic safety, and provide more convenient and efficient service for people.


Aimed at the problems of WWTP,such as low operation efficiency,lack of effective supervision,and extensive operation mode,an operation performance management system of WWTP was designed and developed.Based on three-tier B/S architecture,the system consists of data collection module,data management module,index algorithm module,process management module,user right management module and result display module.The system can provide a perfect digital solution for the evaluation and management of WWTP performance,and it can be used as a reference to implement the performance management in wastewater treatment industry.


The work is based on the results of treatment of 90 patients with a diagnosis of vestibular schwannoma. The analysis of an MRI, neurological status, surgical complications. We used the standard diagnostic system: neurological examination, neuro-ophthalmological evaluation, otoneurological, audiometry and neurophysiological methods. In our work we used neurophysiological monitoring includes registration acoustic stem evoked potentials, electroneuromyography facial muscles, registration of the action potential of the auditory nerve (the first time). In our study we achieved excellent performance indicators for the acoustic-facial nerve group in combination with a high percentage of radicality surgical tumor. They discussed the main aspects of surgical treatment to preserve the function of the auditory analyzer, facial nerve, and the importance of the use of intraoperative neurophysiological monitoring. The analysis of the vestibular-cochlear damage nerve depending on the size and the nature of tumor growth.


The logistics of the clothing industry in south Sichuan is facing the problem of higher cost and lower profits.In this essay it contributes a third-part joint distribution logistic model based on an extensive survey and analyzes the possibility from the perspectives of operation,cost,profit and development space to identify the feasibility of this logistic model.


The problem of testing for the exponential distribution (with scale, or both location and scale parameters unknown) against Weibull alternatives is considered. Upper bounds for the power of any invariant test are presented. Tests based upon the maximum likelihood estimator of the shape parameter, or a modification of it, are given which virtually achieve these bounds.


The invention discloses a mushroom dreg compound substrate formula for soilless culture of cucumbers. The mushroom dreg compound substrate formula is prepared through the following method: fermenting mushroom dregs, livestock excrement and enzyme microorganism powder according to the volume ratio as 3:1:0.1, mixing and preparing the fermented mixed fermentation, turf and perlite according to the volume ratio as 6:4:1, and filling a groove to be used. The formula fully uses mushroom dreg resource abandoned by edible mushroom factory production and livestock excrement resource, environment pollution is reduced, production cost is saved, and cucumbers cultivated in the mushroom compound substrate are better than those cultivated in soil and a traditional substrate in the aspects of growth index and fruit yield. A fruit quality index of content of protein, soluble sugar, free amino acid and the like exceeds that of soil cultivation and traditional substrate cultivation.


Abstract Results from two sets of field experiments carried out during 1984 and 1985 revealed that Japanese mint (Mentha arvensis L.) was associated with both broad‐leaf and grass weeds dominant in summer and rainy seasons representing the period of first and second harvests, respectively. The weed biomass exceeded that of the crop from the very beginning of the crop cycle, and the most rapid increase in weed biomass was noted between 30 and 45 days after planting in first harvest and the first 45 days in second harvest. Unrestricted weed growth significantly reduced Japanese mint oil yield by 74.4% and 70.0%, respectively in first and second harvests. The critical period of weed interference was between 30 and 75 days in first harvest and 15 and 45 days in second harvest. Weed infestation during the critical periods caused significant reduction in plant height and herb and oil yields, and weed infestation beyond the critical periods did not have any significant influence on these parameters. The leaf:ste...


With increased demand on freshwater resources for agriculture, it is imperative that more water-use efficient crops are developed. Leaf stable carbon isotope composition, δ13C, is a proxy for transpiration efficiency and a possible tool for breeders, but the underlying mechanisms effecting δ13C in C4 plants are not known. It has been suggested that differences in specific leaf area, which potentially reflects variation in internal CO2 diffusion, can impact leaf δ13C. However, at this point the relationship has not been tested in maize. Furthermore, although it is known that water movement is important for elemental uptake, it is not clear how manipulation of transpiration for increased water-use efficiency may impact nutrient accumulation. Here we characterize the underlying genetic architecture of leaf δ13C and test its relationship to specific leaf area and the ionome in four biparental populations of maize. Five significant QTL for leaf δ13C were identified, including both novel QTL as well as some that were identified previously in maize kernels. One of the QTL regions contains an Erecta-like gene, the ortholog of which has been shown to regulate transpiration efficiency and leaf δ13C in Arabidopsis. Our data does not support a relationship between δ13C and specific leaf area, and of the 19 elements analyzed, only a weak correlation between molybdenum and δ13C was detected. Together these data begin to build a genetic understanding of leaf δ13C in maize and suggest the potential to improve plant water use without significantly influencing elemental homeostasis. Article Summary Quantitative genetics approaches were used to investigate the genetic architecture of leaf stable carbon isotope discrimination (δ13C) in maize. Developing a better understanding of leaf δ13C could facilitate its use in breeding for reduced transpirational water loss. Several genomic regions were identified that contribute to the variation observed in leaf δ13C. Furthermore, contrary to what has been observed in other species, leaf δ13C was not correlated with specific leaf area. Finally, a leaf ionomic analysis indicates that a reduction in transpiration, and thus mass flow, would not result in a decrease in nutrient accumulation.


The recommendations on population protein consumption normalization, that were developed by world scientists, government, international and national organizations are analyzed in article The features of protein consumption normalization depending on age groups and health status are considered. Optimal norms of daily total protein intake, as well as the correlation of protein of animal and vegetable origin in the diet are established.


Phenotypic variation in biofilm formation is common in clinical isolates of S. epidermidis. In the current study, nearly 5% of all clinical isolates analysed showed phenotypic variation in biofilm forming ability and electrophoretic mobility (EM). This is the first report of S. epidermidis strains irreversibly switching from biofilm-positive to biofilm-negative phenotype by spontaneous deletion of icaADBC genes which represents a new, possibly common mechanism of phenotypic variation.


The aim of moral education is the embodiment of the education aim in the specific field.Essentially,it is the result of moral value,the integration of its premises,and the value pivot in the moral educating activities.The dialectical relation between the layers of moral education aim requires us to pay attention to the relationship between course aim and last aim,first aim and nonfirst aim when we are learning the moral education aim.


Though considerable research has been conducted on ethical leadership, we still know very little about the antecedents to ethical leadership perceptions. Drawing primarily from social learning theory, we propose a process model by which leader Machiavellianism affects ethical leadership, which is then hypothesized to influence psychological empowerment. In addition, we propose that team member role performance and organization-directed organizational citizenship behavior will be consequences of psychological empowerment. Drawing from a sample of 242 employees reporting to 82 leaders, our findings broadly demonstrate support for our hypotheses and advance our understanding of both antecedents and outcomes of ethical leadership. We discuss the theoretical implications of our findings, along with the practical insights, limitations, and future research opportunities.


The Dutch government is developing a policy in favour of more competition in regional public transport in order to increase the number of passengers, the quality of services and the cost effectiveness. The effectivity of this policy is, however, uncertain. The paper focuses on the key factors of successful regional public transport, and answers the question to what extent the introduction of competition has contributed to that success. The research was carried out by the Transport Research Centre of the Dutch Ministry. Five cities with experiences in competition in the public transport had been selected from a list of European cities with successful public transport and they are used for a detailed case-study. As a control group five other cities where there isn't any competition at all had been examined. The researchers conclude that competition can lead to success in public transport, but only when it is organised in conjunction with tendering. Another very important condition for success is that competition must be an element in a broader strategy. Other elements of that strategy are full integration of urban planning and transport policy, high-quality factors such as good information, speedy services, attractive image, etc. Competition however is not a necessary condition for success. Examples in Germany and Switzerland show that regional public transport can be successful without competition when there is a strong regional authority which is responsible for the public transport. The paper discusses these conclusions and various forms of competition. For the covering abstract see ITRD E105101.


A wireless sensor network is composed of a large number of low-cost devices distributed over a geographic area. Sensor nodes have limited processing capabilities therefore simplified protocol architecture should be designed so as to make communications simple and efficient. Moreover, the power supply unit is based on an energy-limited battery the networks should be aimed at minimizing the energy consumption. A forwarding scheme for WSN aimed at combining low computational complexity and high performance in terms of energy efficiency and reliability. The approach relies on a packet-splitting algorithm based on the BURST algorithm. The performance of burst is to be obtained by Shortest Path with Load Balancing (SP).The energy efficiency is low in this splitting process compare to those shortest paths. To estimation of the mean energy reduction factor achievable with the forwarding scheme should be derived and the reassembling is done in destination side, the values to be coded in code block. Simulated using MATLAB simulator. The proposed algorithm outperforms in terms of energy saving and increases the network lifetime. Index: BURST, WSN, SP, ENERGY EFFICIENCY, PACKETS.


An improved genetic algorithm (GA) for design optimization of electromagnetic devices is developed in this paper. Numerical test is done on a classical mathematical problem, and it shows that the proposed method has noticeable advantages over standard GAs. To demonstrate its applicability in engineering optimal design problems, the proposed algorithm, together with the charge simulation method, is used to solve the optimization of a bar-plane electrode model.


Vascular permeability as a function of age was evaluated quantitatively and morphologically in skin of fetal Rhesus monkeys given vasoactive mediators. The response was examined at 90, 120 or 150 days of gestation or at birth and compared to the response of yearling Rhesus monkeys. Skin sites were challenged with histamine, compound 48/80 or bradykinin. Evans' blue and horseradish peroxidase were used as markers of vascular integrity. Evans' blue was quantitated spectrophotometrically. Vascular permeability during fetal life was depressed. Fetal venules and capillaries had poorly formed basement membranes, an abundance of microfilaments within endothelial cells, occasional electron dense endothelial cells and infrequent deposits of extravascular peroxidase.


In this paper, we propose an attitude estimation method using a disturbance model. The proposed method has two parts. One is estimation external disturbance. The magnetic disturbance is augmented as states and estimated by filters. Disturbances are estimated by comparing sensor readings to criteria such as gravity vectors. The proposed method subtracts the estimated disturbance from the sensor measurement and uses it for filter update to maximize the use of measurement information. The second part is that The magnetometer measurement update is performed only on the desired state variable. In relation to magnetometer measurements and attitude, measurements affect not only yaw but also roll and pitch. The proposed method uses a partial-update Schmidt Kalman filter to minimize the effect of magnetometer measurements on roll and pitch. To evaluate the performance of the proposed method, sensor data collected during outdoor exercise by a tester wearing a smart watch was used. Experimental results indicate that the proposed method improves estimation performance.


Measurements of atmospheric near-IR emissions using a field-of-view compensated interferometer are summarized, and an airglow atlas covering the lambda0.9-2.3-microm spectral range is given.


In various application domains, recommender systems explicitly or implicitly act as virtual advice givers. They are not only used to filter large item sets or point users to unknown but relevant items, their recommendations can also help users to make a decision given a limited choice set. Such a system is usually considered effective if the users adopt the recommendations because, for example, the system's suggestions match their preferences or because they generally trust in the system's benevolence and competence. With this work we aim to further explore the persuasive potential of automated recommendations. Our specific goal was to investigate whether the mere presence of a recommendation has effects on the user's choice process. We conducted two online studies in which participants received either no recommendation or a random recommendation for a given decision scenario. The obtained results showed that the pure existence of recommendations can, depending on the decision scenario, make users more confident in their choices and reduce choice difficulty. Furthermore, we observed that in both studies even random recommendations led to an anchoring effect as the participants' choices were measurably biased by the characteristics of the recommended item.


The self-incompatibility genotypes of the parents, 'Golden Delicious' (GD), 'Jonathan' (J) and 'Fuji' (F) were established by analyzing the F2 progenies of 'Hatsuaki' (J×GD) and 'Iwakami' (F×J) derived by back-crossing the F1, 'Hatsuaki' (H) and 'Iwakami' (I) to their respective parental cultivars. That is, the F2 progenies from H×J, J×H, H×GD and GD×H were back-crossed to J and GD and those from F×I, I×J and J×I were back-crossed to F and I. The segregation ratio of compatible to incompatible plants was estimated. Among the 'Hatsuaki' progenies, the segregation ratio of compatible to incompatible from (H×J)×J and (H×GD)×GD was estimated at 1 : 1, (other 6 combinations were 1 : 0). In the 'Iwakami' progenies, those of (F×I)×J, (I×J)×F, (I×J)×J, and (J×I)×F were estimated at 1 : 1, (other 2 combinations were 1 : 0). These results suggest that Jonathan' has no common S-allele with 'Golden Delicious', and 'Fuji' has one common S-allele with 'Jonathan'.


These data include stream water chemistry from headwater streams to large rivers across three national parks in Arctic Alaska: Bering Land Bridge National Preserve, Kobuk Valley National Park, and Noatak National Preserve.


Abstract This article reviews the development of the generalized Mantel–Haenszel statistic and some of its applications. In addition, it is demonstrated that many of the better known statistics for matched sample designs are special cases of the generalized Mantel–Haenszel statistic.


Superconducting nanowire single-photon detectors (SNSPDs) are promising for future quantum technologies. Nevertheless, their performance is limited by thermal-induced latching and detection band limits. In order to overcome these limitations, we propose to develop hybrid systems based on tungsten carbide (WC) nanowires on top of a graphene field effect transistor (GFET). Electrical and electro-optical measurements will be carried out in vacuum under cryogenic conditions (4K). Introduction SNSPDs have very high performance and sensitivity. Nevertheless, their operation is restricted to very low temperatures (T<4.2K) increasing the cost and complexity. When a photon hits the nanowire, it breaks Cooper pairs, generating a hotspot with a finite resistance and, hence, a voltage pulse can be detected. They exhibit very low Dark Count Rate (DCR), low jitter, high detection efficiency, fast time response and polarization sensitivity. However, they have limitations related to the latching or reset time which originates from thermal conductance. Their operating frequency band is also limited to the superconducting bandgap. We propose a new approach based on the fabrication of hybrid systems based on WC and graphene in order to reduce latching and reset. It is known that detectors based on 2D materials exhibit remarkable optical performance. Our strategy consists of growing superconducting nanowires made of tungsten carbide on top of a GFET with superconducting sourcedrain electrodes. Due to the high thermal conductivity of graphene, a fast thermal relaxation of the hot-spot is expected and, therefore, a reduction of the latching effects. Experimental The GFET devices are fabricated by chemical vapor deposition, standard lithography and lift-off methods on SiOx/Si substrates. The WC nanowires are produced via pulsed focused electron beam induced deposition (PFEBID) onto the graphene monolayer. They are characterized by scanning electron microscopy (SEM), atomic force microscopy (AFM), optical microscopy micro-Raman, and photo-voltage time-resolved spectroscopy at low temperature (LT) and high vacuum conditions. Results and discussion The WC nanowires have been fabricated (Figure 1) onto SiOx/Si using 2ms pulsed at 2.5kV with a beam current of 220pA and a total of 200 loops. Aspect ratios higher than 2000:1 can be obtained by this method. Conclusions To our knowledge, this is the first time this fabrication scheme has been employed for the development of similar practical devices. Based on the electrical characterization, further optimization of the nanofabrication process will be performed in order to fulfil the requirements of sensitivity of the fabricated detectors. This research might contribute to the development of quantum technologies, for example, for its use as a single-photon detector in quantum key distribution experiments. Acknowledgments This work is partially supported by the Spanish MICIN-AEI through Grants DETECTA ESP2017-86582-C4-3-R and EQC2018-005134-P. Also, by the Comunidad de Madrid through Grant P2018/NMT-4291 TEC2-SPACE-CM. A.G. and D.G. acknowledge the Office of Naval Research Global for financial support through Grant ONR-G #N62909-19-1-2053 (DEFROST). IMDEA Nanociencia acknowledges support from the "Severo Ochoa" Programme for Centres of Excellence in R&D (MINECO, Grant SEV-2016-0686). A.G. acknowledges ESP2017-83921-C2-1-R, ESP2017-92706-EXP and IJCI2017-33991. References [1] Rogalski et al. Opt. Elect.Rev. 2011; 19(3):346. [2] R.H. Hadfield Nat. Phot. 2009; 3(12):696-705. [3] A Black, FJ Urbanos, J Roberts, M Acebrón, R Bernardo-Gavito. ACS Omega 2019, 4, 14, 15824–15828 [4] I. Guillamón, et al. New J. Phys. 2008; 10, 093005. 10 mm Figure 1. (Top) SEM image of a 100 μm long WC nanowire between to gold electrodes acquired ad 2.5kV with beam current of 220pA. (Bottom) Zoom-in demonstrating a wire width of <50nm. The total aspect ratio of the WC nanowire is higher than 2000:1. Langmuir-Blodgett Biosensors based on Substituted Metallic Phthalocyanines and the Influence of the Enzyme-Mediator Interaction in the Electrochemical Detection of Galactose Alfonso González1, Coral Salvo-Comino 1, Cristina García-Cabezón 1, María Luz Rodríguez Méndez 1 Group UVASens. Engineers School, Universidad de Valladolid, 47011 Valladolid (Spain). (alfonsognoinfgmail.com, coraldeugenahotmail.com, firstname.lastname@example.com, firstname.lastname@example.com) The good performance of Phthalocyanines (Pcs) in Langmuir-Blodgett (LB) films in the development of electrochemical sensors is well-known due to Pcs' electrocatalytic properties that are enhanced when in a nanostructured arrangement [1,2]. Moreover, Pcs' electrochemical properties can be modified by adding substitutents to the aromatic ring [3]. In the present work, nanostructured voltametric biosensors for the detection of galactose were developed using the Langmuir-Blodgett (LB) technique. Tetracarboxy Iron Phthalocyanines (TCFePc) were used to improve the electron transfer catalyzed by the galactose oxidase (GaOx) between the solution and the ITO substrate. The influence of the GaOx-TCFePc-ITO arrangement and interaction between the GaOx and TCFePc were studied. The GaOx-TCFePc-ITO LB films were characterized by means of their Langmuir isotherms, Brewster Angle Microscopy (BAM), UVVis, FTIR and AFM. The electrochemical performance is being studied for different enzyme-mediator configurations, as Figure shows i.e. GaOx dropcasting on the TCFePc LB film, GaOx addition underneath the TCFePc floating monolayer before LB deposition, and covalent bonding between the GaOx amino groups and the carboxy groups of TCFePc. It is expected to find a low detection limit with different sensitivity and selectivity depending on the type of configuration, due to the interaction between the layer and the biological material. Figure: Scheme of the different configuration for the LB films. Acknowledgments: MICINN-FEDER Plan Nacional (RTI2018-097990-B-100), Consejería de Educación Junta de Castilla y LeonFEDER VA275P18 and «Infraestructuras Red de Castilla y León (INFRARED)» UVA01 [1] P. Alessio, P.H.B. Aoki, J.A. De Saja Saez, M.L. Rodríguez-Méndez, C.J.L. Constantino RSC Adv. Combining SERRS and electrochemistry to characterize sensors based on biomembrane mimetic models formed by phospholipids. 2011, 1, 211– 218 [2] J.H. Zagal, S. Griveau, J.F. Silva, T. Nyokong, F. Bedioui Coord. Chem. Rev. Metallophthalocyanine-based molecular materials as catalysts for electrochemical reactions. 2010, 254, 2755–2791 [3] S. V Zaitseva, S. Bettini, L. Valli, A.M. Kolker, N. Yu Borovkov ChemPhysChem Atypical Film-Forming Behavior of Soluble Tetra-3-Nitro-Substituted Copper Phthalocyanine. 2019, 20 (3), 422-428 Hydrogen production by water splitting technique using (g-C3N4)x(CdS)1-x as photocatalyst. M. Gonzáleza, S. Díaza, V. D. Rodríguezb, P. Núñeza a Department of Inorganic Chemistry, University of La Laguna, Tenerife, Canary Island, Spain b Department of Physic, University of La Laguna, Tenerife, Canary island, Spain The present study focuses on the study of photocatalysts oriented to the production of hydrogen using solar radiation as a source of energy. Catalysts based on cadmium sulphide (CdS) and carbon nitride with graphitic structure (g-C3N4) have been synthesized. In addiction the g-C3N4 decorated with CdS have been fabricated with different ratios. The pure catalysts and their composites have been characterized by DRX, SEM and TEM. The hydrogen production was in a homemade setup designed for us. The photocatalytic setup consists of a reactor, a stainless steel ellipsoidal cylinder as reflector, two radiation lamps (Vis and UV) and a mass spectrometer for monitoring the hydrogen evolution. The decorated g-C3N4 catalysts exceed the hydrogen production rate obtained with the commercial photocatalyst P25, based on TiO2, which was used as a reference. The higher hydrogen production rate was achieved for the CdS/gC3N4 ratio of 5/3 (w/w), which was 10 times higher than the values obtained for pure CdS. This work has been financed for MINECO through MAT2016-80933 project


Major fields of improvement in version 5.02 compared to previous versions 5.01 and 3.01, and details on the Level 2 data set from the full mission reprocessing campaign version 5.02-W. Product Specification References  Product Specification: PO-RS-MDA-GS-2009, Volume 15, Issue 3L.  Algorithm Description (ATBD): Lichtenberg, G., Bovensmann, H., Van Roozendael, M., Doicu, A., Eichmann, K.-U., Hess, M., Hrechanyy, S., Kokhanovsky, A., Lerot, C., Noel, S., Richter, A., Rozanov, A., Schreier, F. and Tilstra, L.G., SCIAMACHY Offline Level 1b-2 Processor ATBD, ENV-ATB-QWGSCIA-0085, 2010, issue 1A.  Data Format Description (IODD): Meringer, M., Lichtenberg, G, SCIAMACHY Level 1b to 2 Off-line Processing: Input/Output Data Definition, ENV-ID-DLRSCI-2200-4, 2010, issue 5A. Documents can be downloaded at http://earth.eo.esa.int/pcs/envisat/sciamachy/documents/ Filled by SPPA Engineer 1 Please, note that SCIAMACHY Level 2 Fast Delivery products are not generated anymore since the end of the ENVISAT operations on 8 April 2012. It is recommended to use SCIAMACHY Level 2 off-line products, resulting from the reprocessing campaign version 5.02-W. Readme file for SCIAMACHY Level 2 version 5.02 products Issue 1.2 ENVI-GSOP-EOGD-QD-13-0118 2 Change log This document shall be amended by releasing a new edition of the document in its entirety. The table below records the history and issue status of this document. Issue Date Major Changes 1.0 04/10/2011 ENVI-GSOP-EOGD-QD-11-0110


Summary-A design method for crossed-field guns based on a space-charge-flow solution in crossed fields is given. By using the method of analytic continuation in the complex plane, it is shown that it is possible to find the exact form of the electrodes required The design results in a gun similar to the French "short gun" with the great advantage that the current emitted from the gun and the current density at the cathode can be predicted. It is also shown that by making certain approximations to the exact space-charge-flow solution, a new type of gun can be designed, a Ilong gun,' which can have extremely high convergence. The theory for this latter gun is extremely simple and the electrode shapes can be given entirely in analytic form. ITTRODUCTION HE design of electron guns for crossed-field devices, such as the M-type carcinotron, is usually based on considerations in which space charge is neglected. Consequently, it is difficult, if not impossible, when using these design procedures, to calculate the emitted current from a gun or the current density at it's cathode. iLZoreover, when it is desired to design a gun of high convergence for use in a millimeter-wave tube or a high-power crossedfield traveling-wave t'ube, space-charge density becomes of paramount importance, and the trajectories of the electrons in the gun are controlled by t'he space charge. Consequently, it would be of great help to be able to take space charge into account in the design of such guns. We shall describe here an approach to gun design which is based on the space-charge-flow solutions given many years ago by Benha,m,' by Brillouiq2 and by Slater.a We shall show that the use of such space-charge solutions makes it possible to predict a possible flow suitable for highly convergent guns, for which the current density, electron velocity, potential at any point, and any of the other required parameters of the system are known. This approach to gun design is similar to that of Pierce. Here we use a known space-charge flow in crossed electric and magnetic fields instead of Langmuir's solution as the basis of a gun design. As in Pierce's4 paper on electrode design for parallel-flow guns, we shall use the method of complex variables to find electrodes to give the right


Pessimism and skepticism dominate this most recent work by Martha Brill Olcott, one of the leading scholars of Central Asia and the Eurasian realm. Her central theme is that, even with abundant natural resources, an educated population, and a situation between East and West, Kazakhstan's seemingly bright future and promised prosperity failed to materialize. In short, political and economic corruption has dominated the transition from Soviet dependency to post-Soviet independence.


An electrostatic chuck and a substrate processing apparatus including the same are provided to uniformly and rapidly deliver heat to the substrate by setting up a heat spreading unit between a direct current electrode and a heating unit. An insulating plate(126) of the ceramic material is combined with the top of body. A direct current electrode(128) is installed inside the insulating plate. A heater(130) is built in the insulating plate at the lower part of the direct current electrode. A thermal diffusion plate is built in the insulating plate between a heating unit and the direct current electrode. The body comprises a stepped part(132) which is lower than the central part. The stepped part is united with the focus ring. The focus ring is formed of the ceramic material.


We studied the temporal and spatial dynamic evolution of seismicity factor A-value before strong earthquakes,especially before the first shock in the active period of strong earthquakes in Yunnan.The results show as follows:(1) A-value would appear evident high value near future epicenters during 1 ~ 2 years before strong earthquakes,abnormal value is A≥0.6.(2) The high value anomalous areas of A≥0.6 mainly distributed in the surrounding areas or the boundary areas of Yunnan Province,but rarely distributed in the inner of Yunnan Province during 3 ~ 4 years before strong earthquakes.With the approach of the strong earthquakes occurred,the areas in which A-value was abnormal expanded gradually and moved toward the future epicenters or the inner of Yunnan Province.During one year or 1 ~ 2 years before strong earthquakes,the unit area in which A-value was abnormal in Yunnan and the ratio of the unit area in which A-value was abnormal between inside and outside of Yunnan significantly turned and picked up.


Background: The role of Artificial intelligence (AI) which is defined as the ability of computers to perform tasks that normally require human intelligence is constantly expanding. Medicine was slow to embrace AI. However, the role of AI in medicine is rapidly expanding and promises to revolutionize patient care in the coming years. In addition, it has the ability to democratize high level medical care and make it accessible to all parts of the world. Main text: Among specialties of medicine, some like radiology were relatively quick to adopt AI whereas others especially pathology (and surgical pathology in particular) are only just beginning to utilize AI. AI promises to play a major role in accurate diagnosis, prognosis and treatment of cancers. In this paper, the general principles of AI are defined first followed by a detailed discussion of its current role in medicine. In the second half of this comprehensive review, the current and future role of AI in surgical pathology is discussed in detail including an account of the practical difficulties involved and the fear of pathologists of being replaced by computer algorithms. A number of recent studies which demonstrate the usefulness of AI in the practice of surgical pathology are highlighted. (Continued on next page) © The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. * Correspondence: email@example.com Department of Pathology and Clinical Laboratory, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan Full list of author information is available at the end of the article Ahmad et al. Diagnostic Pathology (2021) 16:24 https://doi.org/10.1186/s13000-021-01085-4


INTRODUCTION: Communication is essential to the provision of safe and high-quality patient care, especially on a busy unit such as labor and delivery. Debriefing allows for situation reflection and helps to improve interdisciplinary communication. We sought to evaluate the effect of debriefing after all deliveries on communication and perceptions of patient safety culture with the ultimate goal of improving the quality of care. METHODS: A 10-item survey was distributed to all labor and delivery staff (nursing, attending physicians, midwives, residents, obstetric anesthesiologists) before and 6 months after the initiation of universal debriefing on labor and delivery. We assessed the frequency of participation in debriefings and current perceptions of communication and safety culture. Beginning in April 2013, all staff were encouraged to have a short debrief after each delivery focusing on what went well and possible improvements. Survey data were analyzed with &khgr;2 tests. RESULTS: One hundred sixty-nine staff were surveyed and there was a 62% (n=105) and 52% (n=89) response rate before and after, respectively. Eighty percent of staff reported that they "never" or "rarely" participated in debriefings before compared with only 31% after (P<.001). After implementation, staff were more likely to agree that there was open communication during debriefings and in general (P<.001, P<.001). Staff were also more likely to strongly agree that they feel free to speak up regarding issues that may affect patient care (P=.03). CONCLUSION: Universal debriefing has improved communication on our labor and delivery unit. Staff have reported improvements in open communication, which directly correlates to improved safety culture and improved outcomes.


This experiment was conducted to determine the effects of extracts from fruit by-products on the blood characteristics, antioxidant activities, and immune response to Escherichia coli lipopolysaccharide (LPS) in growing pigs. A total of 96 pigs ((Landrace × Yorkshire) × Duroc) with an initial BW of 27.94 ± 0.92 kg were used in a 6-week feeding trial. The pigs were randomly placed into one of four treatment groups with six replications (four pigs per replication) per treatment according to their initial BW. Treatments were: 1) CON (basal diet), 2) PRO (CON + 0.5% procyanidin), 3) HES (CON + 0.5% hesperetin), 4) TAN (CON + 0.5% tannin). At the end of the sixth week, five pigs (total 20 pigs, BW = 27.94 ± 0.92 kg) were selected from each treatment and injected with LPS (100 µg/kg of BW). Blood samples were collected 3 h after LPS injection to assess anti-oxidative and inflammatory responses. After the LPS challenge, the concentration of serum cholesterol decreased with fruit by-product treatment compared with CON (p<0.05). The administration of TAN increased the concentration of blood total protein compared with the CON group 3 h after LPS challenge (p<0.05). The albumin concentration was also higher with PRO treatment compared to HES treatment (p<0.05). The concentration of IgM was increased by fruit by-product supplementation at 0 and 3 h (p<0.05). In addition, IgG concentration was higher in PRO, HES, and TAN treatments compared to CON treatment at 0 h, and IgG concentrations were also higher in the HES group compared to the CON group at 3 h (p<0.05). The concentration of IgA also increased with fruit by-product treatments at 3 h (p<0.05). In conclusion, dietary supplementation with fruit by-products may moderate the immune response after a LPS challenge in growing pigs.


: In this paper a control algorithm is presented for a nonlinear system defined by a nonlinear mapping F : Rn f--7 Rn of input states to output states of the system, for the problem of motion in the R" space of output states along the given trajectory. The application of this algorithm in nonlinear optics is presented, for the control of light polarization transmitted through the Fabry-Perot resonator filled with a material with nonlinear optical properties. The calculated trajectory in the space of polarization states of output light leads to the phenomenon of optical bistability, i.e. sudden changes of output polarization induced by small variations of the input p arameters, and the dependence of the current state of light polarization on the history of the system.


A device for the prophylactic treatment of dental caries by mechanical massage treatment of the dental enamel has a tool holder fitted with a head in which a massage cup can be fixed. In its interior the tool holder has devices for rotating the massage cup about its axis. By a translation device, the massage cup (4) is brought into an alternating rotary movement about its axis. The translation device is located in the interior of the tool holder and translates the continuous rotary movement of the motor shaft into an alternating rotary movement. This alternating rotary movement is transferred via the head of the tool holder to the massage cup.


A general superalgebra of vector type is a superalgebra obtained by a certain double process from an associative and commutative algebra.


Abstract This study aimed to evaluate changes in the attitudes of Japan's post-war youth towards gender equality and sexuality, and to examine whether these attitudes bore a relationship to school education. Different generations were delineated based on changes in courses of study and year of birth, and semi-structured interviews were conducted enquiring about experiences and opinions during secondary school days. We examined sexuality education in both junior high school (ages 12–15 years) and high school (15–18 years), views on premarital sex, views on marriage and divorce, and views on gender roles. Fifty-three survey participants were involved in the study: 30 women and 23 men. The characteristics of each generation were examined in relation to corresponding courses of study and the textbooks available in junior high and high schools, identifying both homologies and differences between the messages courses contained and the expressed beliefs of different generations of informants.


Part I Intentions and Means A Pronouncements by Members of the CCP Leadership B Offical Policy Part II Effects and Consequences C Purging the Party D Making Rebellion E Revolutionary Culture F The Economy G Mutual Perceptions: Chinese and Western Part III After the Event H The Trouble with History: Official Verdicts I Ordinary People Remember


A generic valon potential invariant under U(1)\x SO(3) is used to determine whether the horizontal symmetry of leptons is $A_4$, $S_4$, or some other finite subgroups of SO(3). Valons in the potential are assigned SO(3) spins 0, 1, and 2, for these are the only ones that can couple to the three generation of fermions with horizontal spin 1. This potential causes a breakdown into three possible phases with three different symmetries. Phase I has an $A_4$ symmetry suitable for leptonic mixing. Phase II has an SO(2) symmetry and phase III has a $Z_2\x Z_2$ symmetry, both capable of describing Cabibbo mixing of quarks. Phase II has to be rejected on phenomenological ground, but phase III yields block diagonal and hierarchical mass matrices appropriate for quarks. No other non-abelian symmetry such as $S_4$ is present.


The recently proposed topological criterion of concertedness was complemented by a procedure allowing the variational determination of reaction paths characterizing the detailed course of bonding reorganization in modified More O'Ferrall diagrams. The proposed approach, allowing the simple unequivocal classification of reaction mechanisms is demonstrated with examples of several selected pericyclic reactions, both forbidden and allowed. The mechanistic conclusions obtained are in qualitative agreement with the predictions based on expectations from Woodward-Hoffmann rules and independent theoretical calculations.


This research aims at finding out the students' ability in writing an explanation at first semester students of English Study Program of Nusa Cendana University, Kupang NTT .  The researcher focuses on evaluating the students' writing ability in five aspects of writing namely content, organization, grammar, vocabulary, and mechanics.  The researcher applied the quantitative method and descriptive analysis design. The research was conducted in August 2019. This research was conducted at First semester students of the English Study Program of Nusa Cendana University, Kupang.  The population of this research was First semester students of the English Study Program of Nusa Cendana University, Kupang in the 2020/2021 academic year. The number population is 160 in four classes. The researcher took 5 students from each class as the sample of the research.  Therefore, there were 20 students as a sample. The test was used to find out the students' ability in writing explanation text.  In collecting data, the researcher asked the students to write an argumentative essay by choosing one of the given topics. To analyze the data, the researcher focused on evaluating the students' writing in five criteria. The result of the research shows that the mean score of the test is 6.86. It shows that the students have an average degree of capability in writing explanation text.   The biggest problem for the students in developing an explanation text is the organization (43%), it followed by the language use (37%), vocabulary (33%), content (30%), and the smallest problem is mechanics (30%).  Some factors that hamper the students in writing: 1) the students face difficulties in expressing ideas, choosing appropriate words, and arranging ideas in writing, 2) the students seldom practice their writing skill, 3) the students still find difficulty in using punctuation in writing from, 4) the students do not enrich themselves with knowledge.


Although wild-type polyoma virus does not productively infect murine embryonal carcinoma (EC) cells, a number of mutants (PyEC mutants) that do infect undifferentiated EC cells have been isolated. All PyEC mutants have DNA sequence alterations within the enhancer region of the viral genome. This report describes an activity present in nuclear extracts of F9 EC cells which, by "footprint" analyses, binds specifically to a small region of about 20 base pairs (nucleotides 5180-5200) within the subregion of the polyoma enhancer designated as the B or beta element. While no difference in binding of factor was detected between wild-type polyoma enhancer and the enhancers of the PyEC mutants, PyF111 and PyF441, which had been selected for productive infection of F9 cells, definite differences between wild-type and mutants were observed in the digestion patterns of their naked DNAs with either DNAase I or exonuclease III. This difference was restricted to the region around the point mutation (nucleotide 5258) common to these mutant DNAs.


In this charming tale, the fox has terrible hiccups and decides to visit Percy to see if he knows a cure. But when the fox arrives at Percy's hut, it's so dark that he tumbles into Percy's washing and ends up giving both of them quite a fright! Nick Butterworth is one of the most successful author/illustrators today. His humour and his beautiful illustrations have made him a household name, particularly for his well-loved Percy the Park Keeper series.


Macroscopical water ecology cycling and the water parameters of increasing drought resistance of Medicago sativa were studied in arid and semi-arid agriculture regions.After conversion from farmland to grassland in arid and semi-arid agriculture regions of hilly loess regions,the authors aimed to achieve highly effective saving water and enhance yield of Medicago sativa,combined the theory of catchment agriculture with production,then through micro-rainwater catchment and furrow planting technique in rainfed cropland,selected the type of different ratio of ridge and ditch,shaped runoff region of alternating ditch with ridge and zonal region of micro-rainwater catchment,and made high effective rainwater harvesting of time and space of pasture in all-year growth periods under limited rainfall condition,then produced the potentiation of water.The ability of water ecology system of grassland were increased and the matching type of catchment and furrow planting were summarized,therefore distinctly increased water satisfied degree and water use efficiency of Medicago sativa.


Recent emphasis has been placed on the central role of the therapeutic relationship in successful treatment. One aspect of the development of an effective relationship is the clinical social worker's use of self. We argue that the use of self happens both consciously and unconsciously and is a dynamic and evolving process in psychotherapy. This evolution can result in the clinical social worker shifting from a stance of doing to being. Drawing from a Japanese tradition of learning, three stages of learning provide a framework for understanding how therapists may transition from a state of doing to being in the therapy. Through this process, the conscious use of self may develop into unconscious use of self. Two case examples demonstrate how expanding and using one's self-awareness and the new knowledge through meaningful learning experiences can shift a clinical social worker's ability to develop and enhance his or her use of self, inviting therapeutic presence and depth.


The defective response of the body tissues to insulin leads to Diabetic condition in human beings. The central nervous system which controls the entire motor unit, suffers degeneration that leads to many complications, of which Diabetes Mellitus disease lies most widespread in India. Present-day medicine such as insulin injection and vildagliptin (Dipeptidyl peptidase4 inhibitor) treatment are associated with serious neuromuscular side effects and nervous impairment. Within this context, aim of our research was to evaluate, by analysing the myocardial dysfunction complexity, the adverse effects induced by vildagliptin in combination with other antidiabetic treatment. Blood glucose level, glycosylated hemoglobin, serum insulin, systolic and diastolic blood pressure, heart rate, myocardial enzymes such as LDH, CK-MB, AST and ECG signals were measured before and after the insulin and vildagliptin treatment in patients. All the above mentioned parameters were altered significantly after the treatment with insulin and vildagliptin. This study may provide evidence to the medical society about the cardiac dysfunction complexity caused by autonomic failure of hypoglycemic actions upon combination therapy of insulin with vildagliptin in diabetes mellitus.


We present a randomized algorithm for computing portions of an arrangement of n arcs in the plane, each pair of which intersect in at most t points. We use this algorithm to perform online walks inside such an arrangement (i.e., compute all the faces that a curve, given in an online manner, crosses), and to compute a level in an arrangement, both in an output-sensitive manner. The expected running time of the algorithm is O(/spl lambda//sub t+2/(m+n) log n), where m is the number of intersections between the walk and the given arcs. No similarly efficient algorithm is known for the general case of arcs. For the case of lines and for certain restricted cases involving line segments, our algorithm improves the best known algorithm of (Overmars and van Leeuwen, 1981) by almost a logarithmic factor.


Nanoparticles are of great importance as antimicrobial, anti-fungal and anti-cancer agents. Available common chemical methods of synthesizing nanoparticles are complicated and not environmentally friendly. However, synthesis using plant extracts is easy, prompt and safe for the environment. Plants are suitable materials due to the presence of various secondary metabolites such as polyphenols, tannins and antioxidants which act as strong reducing and capping agents. We have been trying several medicinally important plants for synthesizing nanoparticles of silver and gold. In this study we have used various parts of Punica granatum plant such as young leaves and fruit as well as juicy seeds. This plant belongs to the family Punicaceae and possesses several medicinal properties. The aqueous extract of juicy seeds (here after referred to as seeds) was prepared and added to the 2% aqueous solution of HAuCl4 for about 15 minutes with vigorous shaking. The color of the solution changed from yellowish red to dark red indicating the synthesis of gold nanoparticles. Various techniques were applied to characterize the synthesis of AuNPs such as UV-Vis Spectroscopy, HRTEM and XRD.


Electrochemical carboxylation of methyl aryl ketones in the presence of atmospheric pressure of carbon dioxide using platinum cathode and dissolved magnesium anode at constant current density of 10 mA/cm 2 gave the corresponding α-hydroxy-α-methyl carboxylic acids in 79-84% isolated yields. The precursor of cicloprofen, α-hydroxy-α-methylfluorene-2-acetic acid (1a) and biprofen, α-hydroxy-α-methybiphenyl-4-acetic acid (2a) were readily obtained in good yield by a similar electrochemical carboxylation of 2-acetylfluorene (1) and 4-acetylbiphenyl (2). Cyclic voltammetric studies showed that the reaction is reversible indicating the preferential generation of stable anion radicals from methyl aryl ketones and that further addition of carbon dioxide does not take place in these electrochemical carboxylations.


98% of Serbian economy are SMEs. They make 47% of GNP, 54% of employment, 50% of revenues, 44% of profit., employing 2 employees per enterprise. There are 26,9 enterprises per 1000 inhabitants (in EU its 43, in CIT countries 31), 0,31 enterprise per square meter. According to the SMEs development index, Serbia has got 200 USA $ per capita, gray economy makes 40%, unemployment rate 30% with low entrepreneurial innovative activity, seen in added value goods and services for the export and competitiveness of the entrepreneurship sector itself. Quality of the output emphasis problems in financial, fiscal, legislative, education policy and synchronized strategic support measures of stakeholders.