The title reaction has been investigated in the temperature range of 403–446 K. Monoiodogermane and di-iodogermane together with hydrogen iodide were the main products, although at high conversions at least one other product was formed. GeH3I is clearly the primary product. Initial rates were found to obey the rate law

over a wide range of initial iodine and monogermane pressures. Secondary reactions (of GeH3I with I2) affect the subsequent kinetics, although at sufficiently high initial reactant ratios ([GeH4]0/[I2]0 ≥ 100) an integrated rate equation fits the data with the same rate constants as the initial rate expression.

The observed kinetics are consistent with an iodine atom abstraction chain mechanism, and for the step

log k1 (dm3/mol·s) = (11.03 ± 0.13) – (52.3 ± 1.0 kJ/mol)/RT ln 10 has been deduced. From this the bond dissociation energy D(GeH3H) = 346 ± 10 kJ/mol (82.5 kcal/mol) is obtained. The significance of this value, together with derived values for Ge–Ge and Ge–C bond strengths, is discussed.


A frequency domain measurement around 60 GHz is described to evaluate the effectiveness of frequency diversity in mitigating the effects of multi-path fading in indoor microcellular channels. The frequency diversity for 150 MHz and other channel bandwidths to accommodate modulated signals with data rates up to 150 Mb/s is presented. Measurements are repeated under identical test conditions. The receive omni-directional antenna replaced by a directional horn to characterize the effect of the receive antenna radiation pattern on the indoor channel.


We propose and experimentally demonstrate a service‐aware optical transport system. The proposed service‐aware optical transport system makes a flow based on service type and priority of traffic. The generated flow is mapped to a corresponding sub‐λ for transport over an optical network. Using sub‐λ provided by the centralized control plane, we could effectively provide quality‐of‐service guaranteed Ethernet service and best‐effort service simultaneously in a single link. The committed information rate (CIR) traffic and best‐effort traffic are assigned to different sub‐λs. The bandwidth of the CIR traffic is guaranteed without being affected by violation traffic because the bandwidth is managed per each sub‐λ. The failure detection time and restoration time from a link failure is measured to be about 60 µs and 22 ms, respectively, in the ring network. The measured restoration time is much smaller than the 50 ms industry requirement for real‐time services. The fast restoration time allows the proposed service‐aware optical transport system to offer high availability and reliability which is a requirement for transport networks.


A functional division within the immune response has become generally accepted in recent years. Functions associated with cell-mediated immunity are mainly dependent upon the thymus-influenced (T) lymphocyte (1, 2), whereas antibody production is generally dependent upon the non-thymus-influenced (B) lymphocyte (3). However, there is considerable evidence that, for at least some antigens, T cells also participate in the antibody response (4, 5). A considerable body of knowledge regarding the nature and function of the two cell types has accumulated, but little is known concerning their relative specificities. Several reports have dealt with cellular cross-reactions between antigens which exhibit little or no humoral cross-reactivity (6-8), a phenomenon which suggests differences in the specificities of the two cell types. A report from this laboratory (9) demonstrated a similar phenomenon with egg white lysozyme and its reduced and carboxymethylated derivative, CM-lysozyme. These two forms of lysozyme, which are well documented to be non-cross-reactive at the humoral level (9-11) were shown to cross-react with respect to several parameters of the immune response, namely delayed skin reactivity, migration-inhibitory factor production, stimulation of splenic lymphocytes, and cyclophosphamide-induced tolerance. The experiments presented herein demonstrate that this crossreactivity extends to neonatally and adult-induced tolerance.


Modern language is exposed to strong intra structural and functional differentiation, therefore, sexual stratification does not play a significant role in language matters. However, owing to some social reasons, among which social organization, social inequality, and psychological features are considered to be of primary importance, any language has manifestations of male / female variability.


This paper introduces the characteristics and properties of color model, and presents the definition of color model,mainly study the description method of surface - color model based on STL files. The experimental results showed that this description method is effective.


Conclusion Chronic erythrocytic polycythemias were produced in adult female domestic fowl (chicken): (a) hormonally (by androgen injection) at sea level, or (b) by protracted high-altitude (12,500 ft) exposure. Plasma volumes were determined directly by injected 131I human serum albumin dilution methods. Total body erythrocyte and blood volumes were calculated from plasma volumes and adjusted peripheral hematocrits. Androgen treatment or high-altitude exposure similarly increased the hematocrits approximately 45% and the body erythrocytic volumes approximately 65%. These two procedures, however, affected the plasma volumes differently. No change in plasma volume was found at high altitude; however, there was a significant (17%) reduction in plasma volume in the androgen-treated birds as compared with either the sea-level controls or the high-altitude birds. It appears, therefore, that the vascular system of the body accounts for an increase in erythrocytic mass by either (a) a reduction in plasma volume or (b) no change in plasma volume, in which case differential changes occur in total blood volumes.


CONCLUSIONS:
GIST in Indian population shows slight male preponderance. Also, GI bleeding as a chief presenting complaint, while not infrequent, is superseded by abdominal pain, which was the most common presenting complaint in our study. In most Indian series, including our study, small intestinal and stomach GISTs have similar incidence; also, extraintestinal GISTs appear to be more common in India. The incidence of metastatic disesase and unresectable disease also seems to be lower in the Indian population. Most gross and microscopic histopathological data Indian studies appear to be correlating well with international studies.


Mergers and acquisitions are the revolution strategies to restructure a business where the competitions are reduced and existing markets are protected. In the recent years Indian Banking industry had also adopted the strategies to increase the market share of the business and to control the competition. The study is an effort to analyse the financial performance and shareholder value of the select banks. The share holder value of the select banks are calculated through economic value added (EVA) tool. The performances of the banks are measured with profitability and productivity ratios. Paired t-test is used for testing the statistical significance of the ratios of the select banks. Mergers help banks to strengthen their financial base to expand their operation and reduce their cost of operation. The study covers a public sector bank and a private sector bank which were involved in merger during 2006-07 and 201011 respectively. The results suggest that banks had improved efficiency and increased the shareholders value through strategic mergers. Required data were collected from the Capitaline Plus Database. It was found that the in post merger period there is increase in the economic value added of the banks under the study.


OBJECTIVE: To explore the resource and solution of the expired drugs in citizen family through investigating its constituents and expired time.METHODS: By a random sampling,the records of the reclaimed drugs of a total of 1 000 cases collected from 6 drugstores were analyzed statistically.RESULTS: The main expired drugs reclaimed from citizen family were cardiovascular and cerebral vessels drugs,drugs for respiratory disease,and reinforcing and regulating drugs,and most of which were overdue 50 months ago.CONCLUSIONS: The situation of expired drugs in citizen family is serious,thus measures such as reclaiming expired drugs and popularizing knowledge about taking drugs should be taken to tackle the problem of expired drugs.


The West is not the only interlocutor of, nor the singular anchor for, self-imagination of the Third World. Now, we are meeting another "other", from the grassroots level to the level of knowledge production. These sorts of "other-other" encounters not only generate new questions, theories, research practices and teaching methods, but also demand that we reconsider our position and positionality beyond the classic contexts of "West/ Rest" or the "native back home". On 17 January 2020, a group of early-career, Westerntrained "Chinese" scholars gathered together at SOAS, University of London to attend a workshop on "Chinese Positionality: A Reflexive Discussion on Conducting Research in/ on Africa", which, as a peer put it, provided a "rare comfortable place" to talk about our experiences, struggles and reflections on doing research overseas and in particular in locations across Africa. Our panellists were invited to reflect on our position (both self-positioning and how we are positioned) in the "field" and in the knowledge production regime, and on the impact of our position and biographies on the research process. Despite the popularity of ethnographic methods in many areas of study, these kinds of reflections are often excluded by the social sciences as unwanted "noises" and end up as anecdotes, complaints and gossip around private dinner tables. Whereas the discussion was heated, the workshop actually ended up being "very Chinese, very white". When I was confused by the possible lack of interest of African scholars in "Chinese positionality", a peer in African studies said: "How many African scholars are there in London?! They are busy in re-constructing African knowledge, which has always been subjected to Western epistemic violence. And, probably, China, to African scholars, is just another superpower". If position and positionality are relational, there are barriers between different bodies of knowledge, preventing us from getting a full picture of knowledge production about Africa and an understanding of our location within it. One may ask then: why "Chinese positionality"? Both African and Western scholars have written on how value orientations and research agendas are dependent on the perceived positions of the authors in society as well as the politics of knowledge production (e.g. Mama 2007; Mkandawire 2006; Vanner 2015). Meanwhile, scholars have also questioned the potential that essentialism has to shape how we think about human identity and power asymmetry in relation to "positionality" (Robertson 2002). Probably one of


A purely electronic mechanism for superconductivity in disordered Fermi systems is given. It is based on long-time-tail effects in electronic correlations, is strongest in two-dimensional systems, and leads to spin-triplet even-parity pairing. Estimates are given for the mean-field transition temperature to the superconducting state. The superconducting state is discussed in detail. In particular, the superconducting gap function, the tunneling density of states in the superconducting phase, and the low-temperature specific heat are computed. We compare and contrast these results with those for conventional superconductors. We also discuss which classes of materials might provide an experimental realization of the superconducting state discussed here.


The first resonance of the tyre air cavity can significantly affect vehicle interior noise at frequencies around 200 Hz. The insertion of a sound absorbing liner inside a tyre is known to be an eff ...


'The authors are developing advanced seismic data processing, imaging, and inversion methods for high resolution seismic reflection/refraction imaging and material property estimation of the shallow subsurface. The imaging methods are being developed to map the structural and material properties of aquifers and aquitards. This report summarizes work completed in the first seven months of a three year project which began in November 1997. The research is proceeding along three lines: data acquisition, data processing, and algorithm development.'


The acoustic energy loss in surface acoustic wave filters using grating waveguides is investigated experimentally. The propagation loss in the waveguide formed on a ST-cut quartz with aluminum grids, which have the period detuned from that of the Bragg condition, is evaluated to be small as 2×10-3 dB/wavelength. However, it is revealed that the extra energy loss arises with a short waveguide length and before surface acoustic waves (SAWs) launched by the interdigital transducer (IDT) enter the waveguide. Based on the experimental studies on these extra energy losses, the insertion loss in the reflector filter using a SAW grating waveguide is reduced by 2 dB by increasing the aluminum film thickness.


The development of drones has captured the attention of hobbyists and investors alike; drones now have greater commercial and military applications owing to their relatively small size and ability to fly without an on-board pilot. However, certain drone applications may pose serious threats to public safety. The most important problem to be addressed is the recognition of drones in security-sensitive areas. This paper presents an approach to recognize drones through sounds emitted by their propellers using Mel frequency cepstral coefficients (MFCCs) technique for feature extraction and the hidden Markov model (HMM) approach for classification. In the feature extraction stage, two schemes for feature vectors (one using twenty-four MFCCs and the other using the proposed thirty-six MFCCs) are applied, where additional dynamic information of the features is added in the latter. The classifier based on HMMs is then trained using the extracted features according to different training datasets in order to validate the effect of the number of sound types in each cluster on the recognition rate performance. We perform experiments for drone sound recognition utilizing various training datasets for the purpose of classifier optimization, as well as for the two MFCC schemes that are applied in each trial, using the same training datasets for a fair comparison. The experimental results finally validate the feasibility and effectiveness of our proposed methods with relatively high recognition rates, even in noisy environments.


PT. X running an examination page hit process in a portal application, to test server performance. Previously, the process is carried out manually. Page Hits Monitoring System is an integrated system to assist management system controls all applications in Pygmalion Scheduled Synchronization (PSS) portal in IT division. The system consists of four applications, namely SQL Server Integration Services (SSIS), SQL Server Analysis Services (SSAS), SQL Server Reporting Services (SSRS), and Monitoring PSS. Monitoring PSS serves to determine count, average, max and min hit of every page accessed by users. Monitoring PSS application developed with ASP.NET programming language Framework v4, IIS 7 web server, and database SQL Server 2008 R2. The system successfully accelerate time uploading data to database server. In addition, data hit reports can be seen by the interval of time specified by users. And if there is a failure process, then data will be stored in a log status.


"Radiographic Testing is a NDT method to detect inherent volumetric discontinuities in materials such as castings and welds" A common type of discontinuity found and most often misinterpreted and evaluated is rounded indications, whether isolated, aligned or clustered. This paper addresses the acceptance criteria of rounded indications based on various codes and standards and intends to lay at rest the confusion related to this type of discontinuity. The following are important considerations: 1. Interpretation of rounded indications based on codes and standards used in the various sectors of NDT. 2. What types of discontinuities can be regarded as rounded indications? 3. What discontinuity sizes can be regarded as relevant discontinuities? 4. What are the acceptance and rejection criteria for relevant rounded indications 5. Compiling relevant student assignments to facilitate the proper understanding of this aspect. Introduction A common type of discontinuity found and most often misinterpreted and evaluated id rounded indications, isolated, aligned or clustered. The goal of non-destructive examination for discontinuities in materials and welds are to determine whether or not the continuity and homogeneity of a component are adequate for its use. Identified discontinuities are relevant as either rejectable or nonrejectable conditions in a part. An evaluation usually is made with reference to a design basis and may include a code or rule-based criteria for acceptance and rejection. The evaluation of a discontinuity generally requires an adequate measurement of its size and location and identification of its character. Discontinuities are evaluated completely by determining their location, number, shape, size, orientation, and type. The term defect has many meanings and is used to describe almost any variation in metal structure: discontinuity, imperfection, flaw, inhomogeneity or heterogeneity. Defects may be of mechanical or metallurgical types. 1.Porosity Porosity pockets or voids usually spherical in shape – is caused by entrapment of gas evolved during weld metal solidification. Spherical gas pockets, non-spherical voids, elongated tubular gas pockets (described as worm holes or tunnelling) can occur. A large isolated gas pocket is also referred to as a blowhole and may be partially filled with slag. More info about this article: http://ndt.net/?id=19589 2 2.Elements causing porosity A major element causing or contributing to formation of porosity is hydrogen, supplied by: 2.1 The gas atmosphere surrounding the arc zone and weld deposit area; 2.2 The presence of moisture in the atmosphere, flux or electrode coating, or water in the area being welded; 2.3 Cellulose or other hydrogen-forming constituents in the flux or electrode coating; 2.4 The base metal itself. The welding arc's intense heat dissociates the water vapour and other hydrogen-bearing constituents. In the atomic state, hydrogen diffuses readily into the molten material. As the molten metal cools, the solubility of hydrogen decreases for several common metals. As molten weld material decreases, hydrogen tends to diffuse out of the weld deposit into the atmosphere and also into the adjacent heat-affected zone of the base material. Temperature decreases, however, generally occurs so rapidly that diffusion does not take place fast enough to allow hydrogen content to remain within its solubility limits in the molten metal. The resulting super-saturation causes the combination of hydrogen and porosity formation. Being lighter the molten metal, gas bubbles tend to rise to the weld deposit's surface. If the bubbles fail to reach the surface before solidification, they will be entrapped as internal porosity. If they reach the surface, they may appear as external or surface porosity. When weld solidification occurs as dendritic growth, the voids may also become entrapped along the grain boundaries. Other impurities may also precipitate out. Gas bubbles may also form by chemical reactions. Thus, porosity tends to form when oxides in the weld puddle are reduced by hydrogen or carbon at or slightly above their melting point. Thus, the presence of deoxidisers, when added to filler metals, may reduce the oxide reducing actions, minimizing in turn the tendency toward porosity formation. Worm holes or tunnelling can be caused primarily by turbulence in the weld pool, usually a result of excessively high welding currents. Among the welding processes, the tendency for porosity formation is greatest in manual metal arc welding with coated electrodes. This is due to the moisture in the coating and the heavier than normal surface oxidation of the core wire. The tendency for porosity is somewhat less with Mig welding. Nevertheless, porosity can form, particularly with the smaller diameter wires which have a high surface-to volume ratio, and may thus contain significant oxidation and absorbed moisture. Grease and oil lubricants on the wire may also provide the hydrogen resulting in significant porosity. The tendency for porosity formation is least with Tig welding. To minimize porosity in aluminium welds, surface treatment is particularly important to minimize the presence of oxides, moisture and other sources of hydrogen. Very rarely has porosity been associated with actual service failures. No failures have been reported in welds where the porosity was applicable code requirement. Quite likely, porosity limits two to four times those now established in codes could be tolerated in the majority of critical service applications. There is significant divergence among the major codes on the acceptability limits applicable to porosity. Porosity, even under the most liberal acceptability limits of the standards, is not likely to result in service failures so long as it is removed from the surface. Far more critical are surface conditions or notches, which can trigger mechanical or metallurgical failures. Latest results and codes should however be checked.


Blue-tailed forest hawk dragonfly (Orthetrum triangulare) wings exhibit a high transparency at wide viewing angles. The broadband omnidirectional antireflection behaviors of dragonfly wings result ...


AbstractThe application of nanocomposite materials in membrane bioreactors (MBRs) is attractive because of their great potential to enhance the filtration performance and antifouling. This study mo...


where the encoder function fe(·,W) takes the corrupted content vector X0,i∗ of item i as input and computes the encoding of the item, and the function fr(·,W) also takes X0,i∗ as input, computes the encoding and then the reconstructed content vector of item i. For example, if the number of layers L = 6, fe(X0,i∗,W ) is the output of the third layer while fr(X0,i∗,W) is the output of the sixth layer. For φi and η, since we cannot directly take the gradients of L with respect to φi or η and set them to zero, gradient descent is used given the current W. The gradient of L with respect to η is: ∇φiL = ∑


Objective:To observe effect of Winter Disease Cured in Summer Which based on "Method of Nourishing Yang to Dispel Cold"and Acupuncturetherapy in Pulmonary Function and Quality of Life of Chronic Obstructive Pulmonary Disease of Spleen and Kidney Yang Deficiency,and explore the possible mechanism and value in Chronic Obstructive Pulmonary Disease. Methods:Seventy-two cases were randomized into two groups:the control group in which 36 cases were treated with Western medicine.And the treatment group in which 36 cases were treated with times/week.Observe and compare the two groups before/after treatment and at the end of 6 months after treatment with Clinical symptoms,Quality of life,pulmonary function(FEV1/pre,FEV1/FVC,FVC/pre,IC),acute exacerbation of COPD. Results:after treatment;compared with before treatment of cough;expectoration;gasp;the total score of clinical symptoms,daily living,anxiety symptoms score the treatment group were reduced(P0.05) vs the control group there was no significant difference(P0.05),there was no significant difference(P0.05)between two groups.After treatment for 6 months,compared with before treatment of cough,expectoration,gasp,chest tightness,the total score of clinical symptoms,Quality of life in the amount of daily living,social activities,psychological symptoms of depression and anxiety symptoms score and total score,FEV1/pre,FEV1/FVC the treatment group were reduced(P0.01) vs the control group there was increased on chest tightness(P0.01) and reduced in total score of clinical symptoms(P0.05).Treatment group had better reducement than control group.Acute exacerbation of COPD From the income group to the end of treatment after 6 months follow-up results indicated that there was no significant difference on acute attack frequency between two groups(P0.01).the treatment group was significantly lower than the control group. Conclusion:Winter Disease Cured in Summer Which based on "Method of Nourishing Yang to Dispel Cold"and Acupuncturetherapy features full distinct characteristics of Traditional Chinese Medicine(TCM),can improve Pulmonary Function in patients with airway effects,may delay or prevent the function of COPD airway gradual obstruction,also can reduce the effects of acute exacerbation and improve the quality of life of COPD patients,possibly through neural,endocrine,immune network combined effect to play.


Objective To investigate the situation of reproductive health of postmenopausal women in Chongqing and to provide a basis for planning reproductive healtth care for these women.Methods A questionnaire of more than 500 cases in Chongqing with postmenopausal women was porformed .Results The mean age of menopause was 48.18 years. National menopause was 94.02%.Optional menopause was 5.98%.Conclusion We found that middle-aged and older women have many symptoms related to menopause. It is necessary to provide reproductive health care for them.


Located in the metallogenic belt on the northern margin of North China Plate,the Xishadegai deposit is a medium-sized porphyry-type Mo deposit recently discovered in Urad Front Banner,Inner Mongolia.The ore deposit is temporally and spatially associated with the potassium feldspar granite.This study provides highly precise dating of molybdenites and host granite.The dating of zircon from Xishadegai granite determined by LA-ICP-MS yielded an age of 245 Ma±10 Ma.Re-Os isotopic dating on seven molybdenites defined model ages from 223.2 Ma to 232.6 Ma and outlined a good isochron age of 225.4 Ma±2.6 Ma(MSWD=0.30).The consistency of the above dating data indicates an accurate time limit for the formation of the Xishadegai Mo deposit and its host granite.Both of them were formed at the end of Triassic and related to the Indo-China acid magmatic activities under the post-collisional extensional setting.Considering other reported data,it can be inferred that a significant magmatism-mineralization(Au and Mo) event occurred during Indo-China Period.This event,however,was modified or destroyed later,and could still be recorded in some area of the north margin of North China Plate It should be highly valued in the future ore prospecting.


This study examines the mobilizing effects of informal political discussions among African-American church attenders. Specifically, I focus on indirect political encouragement through congregant social networks. I utilize data from the 1993-1994 National Black Politics Study to test models of indirect mobilization effects on voting and non-voting political activism. Findings from regression analyses demonstrate that informal political communication in churches is a more effective stimulus of political involvement than clergy messages. In particular, I argue that discussions in religious social networks increases black activism by overcoming the paradoxes of participation, developing a motivating political consciousness in citizens, and producing responsiveness to religious group civic norms. My results suggest that frequent church attendance and expectations of regular con-tact with fellow parishioners serve as important mechanisms for monitoring and re i n forcing civic norms, while clergy messages may be less effective due to their more detached connection with black church attenders.


....................................................................................................................................................... iii Acknowledgement ........................................................................................................................................ v List of Figures .............................................................................................................................................. xi List of Abbreviation .................................................................................................................................... xv Chapter 1 : Introduction ................................................................................................................................ 1 1.1. RA metabolism and signaling ....................................................................................................... 2 1.2. Cardiogenesis and its dependence on RA signaling ..................................................................... 9 1.3. RA and early cardiogenesis ........................................................................................................ 12 1.4. The role of RA in specification of cardiac progenitor pool ........................................................ 13 1.5. The role of RA in determining the A-P patterning of heart tube ................................................ 17 1.6. RA and the formation of outflow tract (OFT) ............................................................................ 22 1.7. RA and the myocardial proliferation in the ventricle ................................................................. 24 1.8. RA and the development of coronary vessels ............................................................................. 29 1.9. RA and the heart regeneration .................................................................................................... 34 1.10. Conclusion .............................................................................................................................. 36 Chapter 2 : Roles of DHRS3 in Retinoic Acid Metabolism in Early Embryogenesis ................................ 38 Abstract ................................................................................................................................................... 38.................................................................................................................................................. 38 2.


Assimilation of ionic cobalt by axenic cultures of four species of anaerobic rumen bacteria was measured using 6oCo as cobalt (II) chloride. Uptake could be measured in all four species but may not represent active accumulation in the case of Lactobacillus casei and Propionibacterium acnes. Significant uptake (89.5% of 6oCo present) was demonstrated by Selenomonas ruminantium from media containing nanomolar concentrations of inorganic cobalt and it was present within the cell as an organic cobalt complex in both lag and log phases of growth.


At frequencies currently used by mobile communications, many of the microstrip half-wavelength resonators are too large to realize miniaturized filters. For this reason, very small-sized microstrip spiral resonators and filters, using high-temperature superconductors (HTS), have been studied recently. In this paper, the resonant and coupling characteristics of microstrip G-type and S-type spiral resonators are investigated first by using an electromagnetic simulator. Then small-sized 4-pole, 8-pole. and 16-pole Chebyshev bandpass filters using S-type spirals are designed, respectively, with a midband frequency f 0 = 1.93 GHz. The frequency responses of the filters satisfy well the desired specifications, and the measured frequency response of the 8-pole HTS filter agrees well with the theoretical prediction.


The vector-like quarks are predicted in many new physics scenarios beyond the Standard Model~(SM) and could be seen potential signatures of new physics at the TeV energy scale. In this work, we study single production of exotic singlet and doublet vectorlike bottom quarks (VLQ-$B$) at future Compact Linear Collider~(CLIC) via the process $e^{+}e^{-}\to B\bar{b}$ with the decay channel $B\to bZ$ and two types of modes: $Z\to \ell^{+}\ell^{-}$ and $Z\to \nu\bar{\nu}$. We calculate the cross sections of signal and relevant SM backgrounds. After a fast simulation of the signal and background events, the exclusion limit at 95\% confidence level and $5\sigma$ discovery prospects on the parameters (the coupling strength $\kappa_{B}$ and the VLQ-$B$ mass) have been, respectively, presented at the future CLIC with centre of mass energy $\sqrt{s}=3$ TeV and integrated luminosity of 5~ab$^{-1}$.


The utility model discloses a leakage protection device for a mine channel power device, comprising an alternating-current and direct-current conversion device (1), a control device (2) and a detecting device (3), wherein the input end of the alternating-current and direct-current conversion device (1) is set to be connected with a three-phase alternating-current power supply of the power device, and the output end of the alternating-current and direct-current conversion device (1) is set to be connected with the detecting device (3); the output end of the detecting device (3) is set to be connected with the control device (2); the output end of the control device (2) is set to be connected with a driving relay; and the detecting device (3) is internally provided with a resistor capable of adjusting a standard direct current value. Therefore, according to the leakage protection device disclosed by the utility model, the leakage protection performance is improved.


This study entitled "Analysis of Factors - Factors Affecting Visits InSangiran Museum of Sragen Regency". The purpose of this study is to analyze the influence of income, distance, age, tourist status, and the tourist category on the frequency of visits at tourist attractions of SangirankonSragen regency. The samples taken in this research are 71 respondents with 46 respondents distribution of local tourists and 25 respondents of foreign tourists. The data of this research were obtained by spreading questionnaires and interviews. In this study using multiple linear regression analysis method Ordinary Least Square (OLS).
The results of the analysis are: (1) The result of normality data test with JarqueBera model is normally distributed; (3) The result of the classic assumption test shows that there is no multicollinearity problem, the problem of heterokesdastisitas, and there is no problem of autocorrelation, (4) The result of t test can be seen that the variables that have significant influence (5) F test results show that the model used exist (6) R2 get the value 56.55% y6ang means 56.55% of variation in the frequency of tourist visits can be explained by income variables, mileage, age, tourist status, and tourist categories, while the remaining 43.45% can be explained by other independent variables beyond the estimated model.


This article investigates aspects of the human relationship with sound and how the acoustic horizon of different communities can represent a cultural reflection of the reality of nations. The work analyzes, from a semiotic and aesthetic perspective, an audiovisual work of great humanitarian importance: Feel the Sounds of Kenya, created by the Swiss artist Cee-Roo. The study considers the treatment of the sound elements of the work, such as the selection of timbres, rhythm, intensity and melody in the composition of an original soundtrack, and also looks at aspects of visual language, such as colors, mise en scene and edition, which end up making the project an admirable tribute to Kenya.


This paper proposes a functional architecture on MS (Mobile Station) for MS. The proposed MS has several management modules and binding tables about authentication and session to provide seamless multimedia services. The binding table about authentication and session to provide seamless multimedia services. The binding table is managed in the MSS(Media Streaming Server) as well as HG(Home Gateway). The MS receives suitable multimedia services by measuring the available bandwidth between the MS the MSS. We implemented testbed which consist of simple home network environment including the prototype mobile station, media server and home gateway.


A case of bilateral hydronephrosis due to a congenital hereditary anomaly was reported. The operation was performed to remove the right kidney and ureter. Correction of the obstruction in the left ureter resulted in the better functioning of the left kidney, although we cannot be sure in the long run. Received 11th August 1978. 112 I .G .N. w i l a w i r y a a n d h a r i a r t i


Traditionally, the UK has been regarded as good at innovation - with many inventions and scientific breakthroughs. So, can this nation rest easy? No. Based on extensive research by the Advanced Institute of Management Research (AIM), it would appear that the agenda for keeping Britain competitive is a demanding one. Six AIM authors report on what the UK needs to know, and do.


The Internet changes everything. It has become more than a simple and an effective way to exchange emails and documents, it is emerging as a critical backbone of commerce. And, it is happening at a faster pace than many thought possible and with which few feel comfortable. And in these heady days of E-everything agricultural economy in India cannot be left behind. Indeed why should it remain behind when it engages around 65 percent of India's population. Agriportals are but the logical step towards modernising Indian agriculture and making agricultural development a nation wide phenomenon.There are around 12 agriportal already in being in India today. Agribusiness's i.e. agrochemical, fertilisers and tractors, seed and other input companies, are promoting majority of them. Some portals are also promoted by agribusiness consulting groups.But if you ask the managers about their Internet businesses, you will get a bewildering array of responses. Some mention the functionality of the web; some highlight their choices of platform. Some trumpet how they use the web to enhance customer service, whereas others point to their success in integrating the physical and digital infrastructure to provide seamless service. Some mention their initial success in creating customer communities. Though some managers do discard the role of the net in Indian agri-businesses pointing towards the dismal state of rural infrastructure in the country and disparate levels of development.These different observations point towards important characteristics of the net; its potential functionality is so broad and varied that we should not and cannot restrict our attention to a few narrow domains. Indeed it is like the proverbial blind men describing their elephant: Different managers see different facets of benefits but do not see the complete picture. Although most businesses are cognisant of the impending changes, the business landscape is fuzzy and fast changing. We are navigating in uncharted waters.How should companies develop effective portal strategies in such a situation? Given uneven development of the rural economy and extremely low telecommunication networks, how is Internet going to add value to those agribusiness which are going digital to support and enhance their business value? Does it make any business sense to go digital? What's going to be the basic business model for independent agriportals promoted by independent promoters? What could be done to make these agriportals and their strategies work?This paper is an attempt to answer above raised questions.


Objectives The aim of this study was to demonstrate the effect of a novel permeation enhancer system using two existing marketed nail lacquers and the delivery of terbinafine through human nail samples in vitro.


In Metoprolol Succinate the Court of Appeals for the Federal Circuit (CAFC) considered whether a later issued patent claiming the compound metoprolol succinate was invalid for obviousness-type double patenting over an earlier patent claiming a specific composition containing metoprolol succinate. In re Metoprolol Succinate Patent Litigation, 494 F.3d 1011, 1015 (Fed. Cir. 2007). The CAFC held that the patent was invalid for obviousness-type double patenting because it claimed an obvious variation of the earlier issued patent. Id. at 1017.


The aim of this study is to analyze at the effect of competence, professional skepticism, integrity and objectivity on audit quality. The research's object is the Auditors of Public Accounting Firms in Surabaya, specificaly senior auditors, supervisors, managers and partners. Using questionnaires data collection and convenience sampling method, which the final samples are 18 Public Accounting Firms, this study finds that professional skepticism and integrity significantly affect audit quality. However, this study fails to prove that objectivity has significant affect on audit quality. Meanwhile this study could not analyze competence because based on validity test, the variable was not qualified. Keywords : Audit quality, Competence, Integrity, Objectivity, Professional Skepticism. ..


This paper was presented at 15:00 hours local time in Ankara, Turkey on 11th September 2001. On the basis of an economic analysis of the world economy it surmises an entry into an 'age of war' – a period of financial and military competition between advanced countries comparable to the period of classical imperialism from 1893-1918. At the close of the session which was 17:00 hours local time, being 8 hours ahead of Eastern time, hence 9:00am Eastern time, I was scheduled for an interview on Turkish television. 'First, there is something you should see', said the reporter. He led me to the television van where CNN footage showing an aircraft impacting the first trade tower. The second impact occurred as I watched. I emerged from the van five hours later and the interview never took place.


ABSTRACT This study presents the extreme gradient boosting (XGBoost) and random forest (RF) models to predict tourism demand by incorporating international COVID-19 cases, international tourist arrivals, and the destination's quarantine policy predictors. Unlike other 'black box' machine learning models, those two tree-based models offer better interpretability with explicit feature importance and tree structure representations. This paper evaluates the accuracy of these models in predicting international tourist arrivals in Indonesia during the COVID-19 pandemic using long-range (January 2008–June 2021) and short-range (January 2018–June 2021) training datasets. The performance of these two models is compared with benchmark models, such as the artificial neural network, autoregressive integrated moving average, and seasonal ARIMA models. In general, the tree-based machine learning models outperformed all benchmark models. International COVID-19 cases and tourist arrivals predictors have dominating feature importance scores in XGBoost models. Meanwhile, Google trends keywords on quarantine policies show significant importance in RF models but not in the XGBoost models. Moreover, RF models are better than the XGBoost models in terms of accuracy and overcoming overfitting cases.


Background: Posyandu is a maternal and baby clinic to decline the infant mortality rate, infant birth rate, and maternal mortality. The success of activities in Posyandu depends on the cadre's activeness. Data obtained from Banyumas district office in 2013 showed that Puskesmas 1 Wangon hads the lowest percentage of active cadres in Banyumas district, especially posyandu in Pengadegan Village (36 cadres) (60%).Aims: This research aimed at identifying some factors related to the activity of cadres in Posyandu of Pengadegan Village, Banyumas Disctrict.Method: This study used an analytic survey method with total sampling of 60 cadres. The independent variables of this research are knowledge, occupation, motivation and government's support while the activeness of cadresis as a dependent variable. The research instruments were questionnaire and cadre attendance document. Data were analyzed descriptively by using Chi Square.Results: The result shows that knowledge, work, motivation and support of posyandu are related to the activity of cadres in Posyandu of Pengadegan Village, Banyumas Disctrict. Cadres' high activeness is influenced by good knowledge about maternal and baby clinic, high motivation, and unemployement.Conclusion: Knowledge, job, motivation and support from other stakeholders are needed to encourage cadres' participation in the maternal and baby clinic. Coaching and refreshing cadres on an ongoing basis and giving them an award can be alternatives to improve their active participation.Keywords: activeness, cadre, Posyandu


Sustainable development of combined electricity and heat system (CEHS) can effectively facilitate the energy transition from fossil energy consumption to comprehensive utilization of multiple energy. The coupled energy system, featured with the risk of components failure and the integrated uncertain renewable energy sources (RESs), can face a safety and reliability operation challenge. Therefore, achieving the tradeoff between the economy and risk aversion for the CEHS operation is an urgent issue to be settled. This paper proposes a contingencies-based distributionally robust co-risk operation model (DRCROM) for the CEHS, which provides the failure risk sample of components applied by the non-sequenced Monte Carlo simulation (MCS) method and the penalty of energy spillage (including wind spilling and load shedding) under contingencies. Moreover, the uncertain power output risk of RESs can be addressed by using the distributionally robust individual chance-constrained (DRICC) methodology with Wasserstein metric ambiguity set. As a result, incorporating the uncertain component state and power output of RESs into the risk operation can be considered in this paper. Case studies can be conducted to give risk analyses that the average violation probability <inline-formula> <tex-math notation="LaTeX">$V_{p}$ </tex-math></inline-formula> and the total co-risk dispatch cost <inline-formula> <tex-math notation="LaTeX">$C^{\text {Obj}}$ </tex-math></inline-formula> are mainly affected by <inline-formula> <tex-math notation="LaTeX">$\varepsilon $ </tex-math></inline-formula>. Contingencies can also increase risk indices and influence the dispatch energy and energy spillage.


This article aims at measuring and comparing the fatigue strength with fully reversed push-pull tests in the case of two different cast irons: ductile and vermicular. Spheroidal Graphite Iron (SGI), also known as ductile cast iron, is nowadays used in a very large variety of applications. It represents a valid option when strength and stiffness are required, namely, when high values of tensile strength and Young's modulus are coupled with appreciable deformation before failure. By contrast, a different cast iron, known as Compacted Graphite Iron (CGI) or vermicular cast iron, presents its benefits in replacing SGI with respect to specific applications. In particular, with better castability, machinability and thermal resistance, SGI is ideal when components suffer simultaneous mechanical and thermal loadings, such as cylinder blocks and heads. While SGI benefits of a wide scientific literature, CGI is a relatively unknown material, especially referring to its response under fatigue loads.


Variable antenna directivity is seen to be one of the keys to achieve multifunction terminals. For consumer terminals, the properties, such as small size, light weight, low price, and low power consumption, are also indispensable. An electronically steerable parasitic array radiator (ESPAR) antenna has been well researched and developed as an antenna satisfying such properties [1]. However, a high-gain ESPAR antenna, for example, an antenna with gain greater than 10 dBi, has not yet been developed. In order to achieve higher gain, the number of elements must be increased. Therefore, we proposed an antenna arrangement involving some Yagi-Uda antennas with a common feed dipole [2]; the beam direction of this antenna can be switched by transforming the dipole elements, except one Yagi-Uda antenna, to electrically invisible state. The advantage of this antenna is that the desired performance can be realized by appropriately designing the unit Ygi-Uda antenna. However, this antenna has drawbacks with regard to mechanical stability, mass production, and compactness. Therefore, a Yagi-Uda sectored antenna with a planar structure is proposed, and its basic performance is investigated.


Based upon the existing theoretical framework, empirical research on successful generic strategies has resulted in various recommendations for strategic management in declining sectors. However, these studies do not consider (aspects of) strategy implementation, and thus ignore the importance of aspects of the implementation for the ultimate success of the proposed strategy. Consequently, it is difficult to uncover some important factors that contribute to the success or failure of the proposed strategies. One such factor is the congruence between the generic 'decline strategy' and its concurrent social strategy. Although some theoretical proposals on this congruency exist, empirical studies on this topic are lacking. Given the exploratory, 'real-life' and process nature of the study, the case-study method is used. This allows us to establish a dialectic relationship between the theoretical proposals available and the empirical observations. The company that is studied is a Spanish state-owned shipyard. F...


Ahnost everyone has watched a local television weather forecast. Observing the maps closely, it is noticeable that the city tends to be 2-10 ° F wanner than the surrounding suburbs and rural areas. This is due to the so-called "urban heat island" effect. In urban areas, there is typically a large number of buildings, roadways, cars, and artificial surfaces. The heat-retaining properties of these surfaces contribute to the formation of the "urban heat island." A good way to understand these properties is to think about how uncomfortable it is to walk on hot pavement without shoes. It is estimated that by year 2025, 80% of the world's population will live in cities. As cities continue to grow, urban sprawl creates unique problems related to land use, transportation, agriculture, housing, pollution, and development. Urban expansion also has measurable impacts on the environment.


interactive system for priority traffic lights applied to public services, the operation is as follows, the vehicle of choice (1), in its approach to the crossing regulated, flowing past the beacon (3). In step, the infrared beam emitted by the beacon (3), located in post or facade, is captured by the reflecting strip (2) adhered to prioritize the vehicle (1). So once the beam reflected on the reflecting strip (2) is sent to the beacon (3). The beacon (3) upon receipt of the infrared beam, sends the detection signal to the controller (4), and based on the schedule set in the same, generates the commands, via a cable (7), both on / intermittence special semaforica head (6), as the green signal, if appropriate, the semaphoric element (5) prioritize the route at the intersection.


A mechanism for maintaining the same communication identity number when intercepted calls are forwarded is embodied in various methods, devices and media- storing software.


This article has examined the local practice of granting permission to bring personal property into prisons. In this regard, the legal and sub-legal regulatory framework governing the range of goods that can be received in prisons and the procedure for granting this permission were studied. Likewise, the main practical shortcomings in the introduction of assets in prisons were highlighted, as well as the long-term effects that this permissive policy of the criminal executive legislator has generated. Finally, recommendations were formulated in solving the theoretical-practical problems addressed in the paper, as well as proposals to amend the regulatory framework in this regard.


A thesis submitted in partial fulfilment for the award of the degree of doctor of philosophy in the school of education, department of special needs education, Kenyatta University. December, 2017


A system of overlapped Raman spectra was formed on the basis of three experimentally recorded basic bands and quantitatively analysed by two statistical methods: target factor analysis (TFA) and evolving factor analysis (EFA). The results were compared with one another and with the true values. For intense bands, the values obtained by both methods were in good agreement with the expected values, while for small shoulders of strong bands quantitative analysis by EFA apparently gave better results than TFA.


Comprehensive network modeling remains a challenge for the security analyst. Complete coverage and depth of detail in network models is difficult to achieve for large and complex networks, especially when significant effort in manual elaboration is required. This paper describes an automated approach to network model acquisition using coordinated bump-in-the-wire devices. The system described here relieves a substantial burden from the modeler while offering improved visibility over competing solutions.


The bond energy density analysis (Bond-EDA), which can evaluate bond energies in molecules by using the results of theoretical calculations, is applied to investigate chemical bonds in Diels-Alder (DA) reaction. Evaluation of the bond energies confirms the bond alternation in the reactant and product quantitatively, and shows that the TS structure is close to the reactant. In the case of regioselective reaction, local stabilities in newly formed bonds in the TS show significant differences, which correspond to the relationship of the bond distances.


A Cartesian grid method for computing flows with complex immersed, stationary and moving boundaries is presented in this paper. We introduce an augmented projection method for the numerical solution of the incompressible Navier-Stokes equations in arbitrary domains. In a projection method an intermediate velocity field is calculated from the momentum equations, which is then projected onto the space of divergence-free vector fields. In the proposed augmented projection method, we add one more step, which effectively eliminates spurious velocity field caused by complex immersed moving boundaries. The methodology is validated by comparing it with analytic, previous numerical and experimental results.


The speed control of induction motor (IM) continued to be developed, especially on electric drive systems. PID control is very popular and is widely used because of its simple structure and robustness. However, those controls will be disrupted when parameters change occurs in the case of dynamic speed. This paper proposed the simplified control strategy using Fuzzy Prediction Gain Proportional (FPGP) of PID control. It has better performance results when it is implemented for IFOC modeling system for the dynamic induction motor of speed control. The rule and prediction of fuzzy logic are used to arrange the scheduling system or to determine the gain value when there is a modification of parameter systems so that the optimal result is obtained. The experimental result of FPGP-PID and PID-ZN systems are compared in terms of transient condition when dynamic speed involve (settling time, overshoot and, undershoot). The output response using proposed method optimation can minimize overshoot to 12% and undershoot to 80%.


China's Anti-Japan War, a great part of the World Anti-Fascist War, is now depreciated by some people. This paper, through revealing many facts, demonstrates the great contributions China had made.


Pharmacological induction of muscle paralysis with PB is frequently used in the newborn to facilitate artificial ventilation. Cardiovascular responses to this drug have not been as well documented in the neonate as in the adult. Sixteen newborn piglets (wt 800-2300 gms) were anesthetized with ketamine (IM) and placed on a Bourns LS-105 ventilator. Heart rate, systolic, diastolic and MAP were continuously monitored. PB was given IV in varying dosages (.03-.72 mg/kg)for induction of complete paralysis. Acid-base imbalance (pH 7.03-7.65) was produced by altering ventilator settings and by lactic acid infusion. Fifty-eight percent of PB injections resulted in an increased MAP (↑X 12.9 mmHg),9% lowered MAP(↓X 16 mmHg)and in the remaining 32%,MAP continued unchanged. The following variables were also analyzed: weight, drug dosage, blood pH and change in heart rate (HR). Analysis of variance revealed that HR changes were the only statistically significant variable (p<.05). A significant rise in HR was noted with either an increase or decrease in MAP, while the HR remained relatively constant when MAP was unchanged. In adults, PB increases HR and MAP; however, in the newborn piglet, the response to PB is variable. Alterations in MAP have significant effects on tissue-organ blood flow. If the variable HR and MAP responses to PB seen in the newborn animal model can be extrapolated to humans, careful monitoring of cardiovascular function is advisable in neonates undergoing muscle paralysis.


This work focuses on a control technique extended second-order generalized integrator with frequency locked loop (Ext-SOGI-FLL) for the synchronization of power converter-based equipment because of ease in digital execution and satisfactory performance. In the existing phase-locked loop (PLL) based control, the loop filter used cannot entirely remove harmonics. Hence, the harmonics in voltage considerably affects the frequency as well as phase extraction, both in dynamic and steady-state situation. To deal with this problem in the implemented system, the VSC (Voltage Source Converter) is gated in the grid-connected mode by Ext-SOGI-FLL control and for an islanded mode, VSC is switched to the PI (Proportional Integrator) control. The implemented control algorithm extracts the fundamental load voltage and current for assessment of phase angle and reference grid current (maintaining the required IEEE power quality standard-519). The FLL based control is also cable of estimating the exact frequency and phase magnitude, which suffer from phase offset due to frequency change. The comparative results validate that the response of Ext-SOGI-FLL in comparison to the existing control algorithm is faster at load and generation perturbations. Simulated results for single-stage solar photovoltaic (PV)-SyRG (Synchronous Reluctance Generator) for pico-hydropower generation, and BES (Battery Energy Storage) based microgrid is simulated in MATLAB/Simulink platform and it is validated it works successfully while feeding local loads uninterruptedly.


Japanese oil companies play the role of maintaining or extending the amount of reserves both domestically and overseas for Japan.In recent years, exploration and development cost have increased dramatically as the well depths are much extended, well locations move further to remote areas and water depths go deeper. Environmental protection requires more complicated techniques and careful management of drilling activities, which boost up total expenditure of projects incurred. These trends make the finance of operators greatly tight and restricted. Besides, these difficulties are compounded by an upsurge of resource nationalism among the oil-producing countries, the price of oil hovering the lower level, and the unfavorable exchange rates for Japanese yen to U. S. dollar. Under such desperate circumstances we are demanded to complete our objectives more precisely and efficiently than ever by devoting our abilities to the work. Thus a comprehensive educational program must be one of the key issues to achieve our goal by cultivating knowledge of individuals.In view of the above, this paper introduces an in-house training program of JAPER (Japan Petroleum Exploration Co., Ltd.) that is composed of the followings:1) education for new employee2) education for drilling engineer3) training for dirlling crew4) in-house seminar


I have noticed a few misprints. In the text, 551 KaXTqTai, 611 comma misplaced, 996 p ap ; in the critical notes, 331 Trpocrtparov y, 632 KiKtWev, 882 ' Wunder wrote ' etc. belongs to preceding verse, 964 /Jao-i?; in the commentary, 80 f. vo-repov, 83—85 ctris, 149 f. ev, 679 \6yov, 801 read '1st. pers. sing.', 898 irofw, 947 transposition necessary, 1238 <Ls; in Appendix, p. 207, 1. 18, insert ' no t ' before ' toHyllus. ' In critical note on 1183, 'Blaydes dp«s, which Nauck and Mekler cite without noticing the a,' the editor is the guilty one. apS> from aupu> has a; cf. Pers. apovp,€v <TT6XOV and Ran. 377. A similar confusion occurs in the index to the Antigone, where under alpta is given a reference to the usage of aupoi.


At the present there exist two different types of riot helmet shells, a thermoplastic and a composite shell. The composite shell is believed to be superior in impact performance, but more expensive and complicated in manufacturing partially due to the fact that the textile reinforcement material has to be cut into pattern pieces before they can be applied to the helmet shaped mould. However, the discontinuation of fibers is likely to reduce the level of protection and shorten the lifetime of a helmet. The aim of this research is to develop a helmet shell consisting of a single-piece of fabric without creating wrinkles and without the necessity of cutting the fabric. For this purpose, a new type of woven fabric has been developed and an apparatus has been set up to drape the fabric to a helmet shell. The helmet shell was manufactured using a single piece of Kevlar woven fabric. In parallel the finite element method is applied to investigate the shock absorption behaviour of the helmet shell made from both multi-piece and single-piece fabric reinforcements. The results show clearly the advantage of the single-piece helmet shell over its existing multi-piece counterpart


BACKGROUND:
Migration is increasing worldwide. In developing countries, more than half of the migrants engages in informal work and short term migration is the trend in India nowadays. Mostly the migrant informal workers engages in construction and manufacturing industry. But the construction workers are disadvantaged, due to the dangerous insecured job, poor living conditions, inadequate social security schemes and have limited access to affordable, quality health care.
OBJECTIVES:
1. To determine the health seeking behaviour among the migrant construction workers at Chennai.
2. To determine the factors influencing health seeking behaviour among migrant construction workers.
MATERIALS AND METHODS:
A cross sectional survey was conducted using a semi – structured questionnaire among 418 migrant construction workers of 16 years and above working in two construction sites in Chennai to determine the health seeking behaviour and the factors influencing the health seeking behaviour among the study population.
RESULTS:
Nearly 89% of the study population were between 16 to 45 years of age. About 30% of them were intra-state migrants and most of the inter-state migrants were from Jharkhand, West Bengal and Orissa. Almost 28% of study participants had no formal education. About 62% of them were working for more than 9 hours a day. The health seeking behaviour seemed to be better for injuries when compared to illness. The migrant workers seek health care when the illness is getting worse. Only 4% perceived their illness as very serious. Majority of them (48%) sought healthcare within 3 days of illness and two thirds among them visited private healthcare facility. Nearly 33% did not seek healthcare facility at all for their illness.
CONCLUSION:
The health seeking behaviour depends mainly on the perceived severity of the illness. Financial constraint was cited as a reason for not seeking healthcare. This should be addressed to the employer and necessary healthcare facilities should be made available for vulnerable low income group. Health education regarding Ergonomics is important in reducing risks to worker's health and also to improve their health seeking behaviour.


This paper presents a method for the design of an indirect model reference adaptive control (MRAC) system for a plant with deterministic disturbances, robust to modeling errors due to unmodeled dynamics and observation noise. In the proposed method, the structure of the controller is determined on the basis of the internal model principle to reject the deterministic disturbance, and its parameters are adjusted by using the estimated plant parameters. Robustness to the modeling errors is ensured by the use of the adaptive law with a dead zone and a fixed compensator of integral type. The adaptive law prevents the adjustable parameters from drifting and the fixed compensator improves the control performance degraded by the use of the dead zone. Stability of the MRAC system is analyzed using the concept of the ℒ2δ norm and the Bellman–Gronwall lemma, based on the properties guaranteed by the adaptive law. Effectiveness of the proposed method is demonstrated by the simulation carried out for a plant with second‐order nominal part and a step disturbance. © 2004 Wiley Periodicals, Inc. Electr Eng Jpn, 146(4): 65–75, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.10190


The product of monotritylation of 3β,19-dihydroxyandrost-5-en-17-one is the 3β-trityl ether, not the 19-trityl ether as previously proposed. In consequence the product of acetylation of the monotrityl ether is 19-acetoxy-3β-trityloxyandrost-5-en-17-one and thus acid-catalysed detritylation of this compound yields directly the 19-acetoxy derivative without the invoking of an acid-catalysed rearrangement. The isomeric 3β-hydroxy-19-trityloxyandrost-5-en-17-one has been prepared as well as a number of 3β-tritylated Δ5-steroids which have been used to study the influence of the trityl ether group upon p.m.r. chemical shifts in this series.


Objective:This study tested the reliability of DNA,which using NaOH method extract from FTA card and kit extraction,in PCR reaction,PCR-SSCP reaction.Method:The concentration and purity of DNA,which extracted in two different methods,was tested by spectrophotometer.Then PCR reaction and PCR-SSCP reaction were proceed and the results were checked up.The samples were the same and the two reactions were proceed in same conditions.Result:The purity of DNA were OD260/280=1.817 and OD260/280=1.806,respectively.The results of PCR and PCR-SSCP indicated no difference between them and success rate is 100% in all 48 samples.Conclusion:Therefore,the DNA samples adhered properly to FTA card,it is reliable which using NaOH method extract DNA,and more simple and inexpensive.It's worth to popularize this method.


In the late Pleistocene, the atmospheric carbon dioxide concentration (pCO2) is thought to be a primary driving force for tropical sea surface temperature (SST) change because glacial‐interglacial changes in tropical Pacific SST covary with pCO2. However, if the regional radiative effects of pCO2 were the only agent of change, tropical SST gradients should have remained similar as pCO2 varied with time. Instead, a new record of SST from the west Pacific shows that tropical SST gradients were different, even reversed, in the past, suggesting an important role for dynamical circulation changes. Specifically, changes in the temperature of upwelled source water, in addition to local pCO2 forcing, influenced tropical Pacific SST. These dynamical changes, rather than pCO2, may have shifted the background state of the tropics and even helped set the stage for the mid‐Pleistocene transition.


Despite the growing attention being paid to the use of Automated Writing Evaluation (AWE) in China, it is still uncertain what factors lie behind EFL (English-as-a-foreign-language) learners' continuance intention to use it. To this end, by adding two external factors (i.e., computer self-efficacy and perceived ease of use) to the expectation confirmation model (ECM), we surveyed 345 Chinese EFL learners and tested a number of proposed hypotheses using their response data. Data were analyzed using descriptive statistics and structural equation modeling (SEM). Results demonstrated that four factors directly influenced EFL learners' continuance intention to use AWE, of which perceived ease of use was the most significant factor. Furthermore, confirmation was the most important factor impacting on EFL learners' satisfaction and perceived ease of use of AWE. Perceived ease of use of AWE played an important role in influencing EFL learners' perceived usefulness of AWE. Implications regarding the findings were also discussed.


Over the past few years an overhaul of the European data protection edifice has been under way. Practically all basic data protection regulating documents in effect until today have either already been replaced or are in the process of being thoroughly amended. This is probably a development that was long overdue, given that all of them have an age of several decades while none of them has been released taking the internet into account. The OECD is the first international organisation that issued any data protection regulations at all: it did so in 1980, and its Guidelines remained unchanged until 2013, when their amendment process was completed. The Council of Europe released its own data protection regulations, formulated in Convention 108, only a few weeks after the OECD; they too remained in effect unchanged over the decades that passed, admittedly complemented by rich secondary legislation, and are now in the process of being amended. However, most of the data protection work undoubtedly takes place within the EU which chose to dominate the international field since it became involved in it, through the EU Data Protection Directive in 1994. The Directive set the EU and international, through its "adequacy" criterion, data protection standard. However, it remained hopelessly outdated, because it was released before the advent of the Internet (although the Court of Justice through its recent Google Spain case showed that there is still some life left in it). The European Commission seized the opportunity presented by the Treaty of Lisbon, and its Article 16 TFEU, and took upon itself the herculean task of reconstructing the whole EU data protection edifice, both from an architectural and from a substantive law point of view


Objective To observe effects of Xinfeng Capsule(XFC) on changes of neuroendocrine-immune(NEI) network-related indicators in adjuvant arthritis(AA) rats,and explore the mechanism on the basis of NEI network.Methods Sixty rats were averagely randomized into normal control(NC) group,model control(MC) group,methotrexate(MTX) treated group,Tripterygium glycosides Tablet(TGT) treated group,XFC treated group.Except for rats in NC group,the remaining rats in other groups were induced to AA model by intracutaneous injection of 0.1 ml of Freund's complete adjuvant in the right hindlimb.Serum levels of 5-hydroxytryptamine(5-HT),dopamine(DA),adrenocorticotropic hormone(ACTH),cortisol(CORT),tumor necrosis factor-α(TNF-α),and interleukin-10(IL-10) in all groups were assayed using enzyme linked immunosorbent assay.Results Compared with those in NC group,serum levels of 5-HT,ACTH,CORT,and TNF-α in AA rats were significantly increased,while the serum level of IL-10 was significantly decreased(P0.05 or P0.01).XFC could significantly decrease serum levels of 5-HT,CORT and TNF-α,and significantly increase the level of IL-10,its effect being significantly better than that of MTX and TGT(P0.05,or P0.01).No significant difference in DA levels was found among five groups(P 0.05).Conclusion XFC can play immunoregulation and anti-inflammatory roles in arthrocele of AA rats by regulating the disorder of NEI network,inhibiting the hyperfunction of HPA axis,reducing the excretion of ACTH,CORT and 5-HT.


In this chapter we discuss the modeling and simulation of shear banding and chip formation during high-speed cutting. During this process, shear bands develop where thermal softening dominates strainand strain-rate-dependent hardening. This occurs in regions where mechanical dissipation dominates heat conduction. On the numerical side, we carry out a systematic investigation of sizeand orientation-based mesh-dependence of the numerical solution. The consequences of this dependence for the simulation of cutting forces and other technological aspects are briefly discussed.


Concrete-faced rockfilll dams have been rapidly developed. Dam construction using soft-rock is a new problem of CFRD. Soft-rock covers over 50% of earth-surface rock, so the research on the technique of soft-rock placement has extensive prospect and great economic benefit. Based on the practices of three real projects——Yutiao, Da'ao and Qiezishan, the paper introduces their field compaction experimentation, the comprehensive analysis of the results, and the measures to improve the placement quality and to reduce the crusting of cracked soft-rocks. All of the experiences obtained from the research may be of greatly beneficial reference for the similar projects since then.


A 23‐year‐old woman with acute leukemia in remission developed fulminant thrombocytopenic purpura coincident with the use of pentamidine iesthionate for treatment of Pneumocystis carinii pneumonia. The platelet count began to return to normal on the 8th day after withdrawal of the drug and an increase in the dose of prednisone. The temporal relationship and the lack of another identifiable explanation strongly suggest that thrombocytopenia was induced by pentamidine.


Moire effect in PMP using DLP and its influence on phase measurement was studied. The projected grating by DLP can be regarded as the process of sampling the analog grating and the acquired grating by CCD can also be regarded as the process of sampling the projected grating. When some conditions of the spatial frequencies between DLP pixel and CCD pixel are satisfied, the moire effect will be appeared. Moire fringe pattern will influence phase measuring precision. The condition appeared Moire effect was discussed and the rule of the influence to the phase measuring precision was given by analyzing the two steps sampling process. The correctness of the discussions was verified by the simulation experiment.


A scalable and robust infrastructure for arbitrary quantum communication and distributed quantum computation will realize enhanced as well as new applications that are beyond the reach of classical communication networks. Quantum internetworking, which achieves large-scale quantum networks by building recursively on smaller quantum networks, is a promising approach. However, there are two big difficulties: decomposing end-to-end quantum communication, which is actually a complex distributed computing spanning classical and quantum computing, into processing for each subnetwork; and supporting future network functionality sustainably. In this work, we propose design principles for a quantum internetworking protocol based on the quantum recursive network architecture (QRNA) utilizing the RuleSet-based approach. We design two distinct approaches for recursion in quantum networks, namely link- and node-recursion. We demonstrate how end-to-end Bell pairs are generated over our internetworking systems, and evaluate the scaling of inputs to the distributed processing, via implementation on the Quantum Internet Simulation Package (QuISP). Our subnetwork recursion demonstrates the long-term future scalability as the size of and demands made on the Quantum Internet.


Micronutrient deficiency has profound effects on physical and mental development eroding the quality of human resources. Micronutrients are also involved in the function of the human system that when deficient lead to potentially harmful infections.An attempt was made to combine the food groups to combat micronutrient deficiency. Sweet biscuits, salt biscuits and burfis were prepared using standard methods. Sensory evaluation was conducted. Results revealed that SBC1, SBC-2 and BC (control products of sweet biscuit, salt biscuit and burfi) scored maximum in all the sensory attributes. Physico-chemical analysis was donefor the three products andresults revealed that, the products contained a better amount of nutrients (protein, fat, energy, carbohydrate, ash, crude fibre, total dietary fibre and beta-carotene) when compared to the control products.Shelf life study was carried out at the interval of 10, 20 and 30th day.Products were packed in LDPE pouch and stored at ambient temperature. Results revealed that, there were significant changes from the initial day up to the 30th day. However, no mould growth was observed on the surface of the products.Consumer acceptability was distributed to 45membersviz. staff members of Dean (Agri) and registrar's building (35 nos.) and girl students (10 nos.). Results revealed that the biscuit and burfi products were accepted by the consumers. It can be concluded that, a combination of food groups will improve the nutritive value of a product and it may help improve the micronutrient deficiencies of the public. Signature of student Signature of the chairperson ¤UÀ¢üvÀ DoÁgÀ UÀÄA¥ÀÄ DzsÁjvÀ ¥ÀÄ¶Ö ̈sÀjvÀ «Ä±Àæt


SWISS-PROT is an annotated protein sequence database established in 1986 and maintained collaboratively, since 1988, by the Department of Medical Biochemistry of the University of Geneva and the EMBL Data Library BAIROCH, Amos Marc, BOECKMANN, Brigitte. The SWISS-PROT protein sequence data bank. Nucleic Acids Research, 1991, vol. 19 Suppl, p. 2247-9 DOI : 10.1093/nar/19.suppl.2247


Hongjun Liu,1,2,* Jyh-Pin Chou,3 Run-Wei Li,1,4 Ching-Ming Wei,3,† and Kazushi Miki1,2,‡ 1National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan 2Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba 305-8571, Japan 3Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan, Republic of China 4Ningbo Institute of Material Technology and Engineering (NIMTE), Chinese Academy of Sciences (CAS), Ningbo, Zhejiang, 315201, People's Republic of China (Received 26 April 2010; revised manuscript received 25 October 2010; published 7 February 2011)


We present a theoretical study of a system consisting of a superconducting island and two quantum dots, a possible platform for building qubits and Cooper pair splitters, in the regime where each dot hosts a single electron and, hence, carries a magnetic moment. We focus on the case where the dots are coupled to overlapping superconductor states and we study whether the spins are ferromagnetically or antiferromagnetically aligned. We show that if the total number of particles is even, the spins align antiferromagnetically in the flatband limit, i.e., when the bandwidth of the superconductor is negligibly small, but ferromagnetically if the bandwidth is finite and above some value. If the total number of particles is odd, the alignment is ferromagnetic independently from the bandwidth. This implies that the results of the flatband limit are applicable only within restricted parameter regime for realistic superconducting qubit systems and that some care is required in applying simplified models to devices such as Cooper pair splitters.


Some patients with an early or latent myeloproliferative disorder (MPD), comprising primary polycythaemia and throinbocythaemia, present with Budd-Chiari Syndrome (BCS, hepatic vein thrombosis). Techniques to examine circulating erythroid progenitors (BFU-E) and X-chromosome inactivation (in females) can be used to diagnose MPDs. These techniques were used to examine if a group of 7 female patients who presented with BCS had evidence to support a diagnosis of MPD. Unilateral Xinactivation and therefore clonality can be studied in females heterozygous for X-linked restriction fragment length polymorphisins (RFLP) by differences in methylation between active and inactive chromosomes. Two polymorphic probes, phosphoglycerate kinase (PGK, at Xq13.3 [BstXI RFLP]) and M27P froin an anonymous locus DXS255 at Xpl1.22 [Pstl RFLP] were used to study inethylation patterns. All 7 patients were heterozygous using M27P and 217 were also heterozygous using the PGK probe. Polyclonal patterns of X-inactivation were demonstrated in granulocytes of 3/7, monoclonal pattern in 1/7 and aberrant patterns in 3/7 patients heterozygous using M27P. Two patients who had aberrant patterns of X inactivation with M27P demonstrated monoclonal pattern with PGK. The 3 patients with monoclonal patterns of X-inactivation ( I M27P. 2 PGK) had BFU-E growth typical of primary MPD. Thus X-chromosome inactivation patterns, in conjunction with erythroid colony studies, can be used to assist in the diagnosis of an underlying MPD in BCS. A STUDY OF CHANGES IN METHYLATION STATUS AND COPY NUMBER AT LEUKAEMIA. B.A. Jennings.DNA Laboratory, Cytogenetics Department, Norfolk and Norwich Health Care NHS Trust, Norwich. The inevitable transformation of Chronic myeloid leukaemia (CML) into an acute phase leukaemia is believed to result from the accumulation of genetic abnormalities by the malignant clone. in a significant proportion of cases this disease progression is characterised by the acquisition of secondary, non random chromosomal abnormalities such as trisomy 8 and molecular genetic changes such as alterations to the c-myc gene which is located on 8q24. Increased expression of the c-myc gene has been associated with the progression of CML, particularly in those cases with trisomy 8. This study examined two alterations of the c-myc gene which can lead to enhanced c-myc expression: gene amplification and alterations in the pattern of DNA methylation in the third exon of the gene. 21 samples were analysed from CML patients at various disease stages. The cohort of patients fell into two distinct populations: those that showed evidence of leukaemic clones evolving with trisomy 8 during the course of their disease and a group that reached the acute phase with no cytogenetic evidence of trisomy 8. Amplification of the c-myc gene was associated with the progression of 20% of the cases studied. No evidence was found for an association between c-myc gene amplification and the acquisition of trisomy 8, moreover the data suggests that an increase in c-myc gene dosage through locus amplification could serve as an alternative to trisomy 8 as a selected genetic change. The c-myc exon 3 site studied was highly methylated in the majority of samples. This site is also highly methylated in normal tissues. Hypomethylation at this site was however associated with the progression of 15% of the cases considered. This epigenetic change has previously been associated with the progression of colorectal cancer and enhanced c-myc mRNA expression. In conclusion, amplification and epigenetic modification of the c-myc gene was found to be associated with progression of a proportion of CML cases. 137 THE c-myc Locus DURING THE PROGRESSION OF CHRONIC MYELOID 138 PROGRESS TOWARDS REFINEMENT OF THE COMMON DELEED REGION ON CHROMOSOME 20q IN MYELOID HAEhMTOLOGICAL DISORDERS F.A. AsimJ.G.R. Gilbert, B. Nacheva*. T.L. Holloway, A.R. Green University of Cambridge Department of Haematology, MRC Centre, Hills Road, Cambridge CB2 2QH and *Dept. of Leukaemia Cytogenetics, Addenbrookes Hospital NHS Trust, Hills Road, Cambridge CB2 2QQ Aquired deletions of the long arm of chromosome 20 are found in several haematological conditions and particularly in the myeloproliferative disorders and the myelodysplastic syndromes. The spectrum of diseases associated with 20q deletions suggests that they may mark the site of a tumow suppressor gene involved in the regulation of normal haemopoietic progenitors. We have recently carried out detailed molecular and cytogenetic analyses of chromosome 2% deletions and identified a common deleted region (CDR) of 16-21 cM. Our results demonsbated molecular heterogeneity of both cenmmeric and telomeriC breakpoints, a finding which supports the existence of a mmow suuuressor gene on 2Oa. Several candidate genes were found to map oit&de thicregion. . We have attempted to refme the CDR by mapping the deletions in an increasingly large panel of samples -from -patients carrying 2% deletions. We have also determined the position relative to the CDR of several additional 20q markers including expressed sequence tags known to map to chromosome 20. In addition we have examined a panel of samples from 50 patients with polycythaemia rubra vera for loss of heterozygosity on 20q. Granulocyte DNA was compared to T cell DNA using a panel of 18 highly polymorphic microsatellite markers regularly spaced throughout the CDR. Clonality of peripheral blood cdl populations from female patients was determined using the HUMARA assay. We found allele loss over large regions on 2Oq in 3 patients, a mte comparable to the reported incidence of 20q deletions in polycythaemia rubra vera. We are currently investigating the molecular basis for loss of heterozygosity in these three patients. 38 British Society for Haematology, Brighton, 3-6 April 1995 139 ABNORMAL TCR Vg REPERTOIRE IN PATENTS WITH CERONIC MYELOID LEUKAEMIA (CML). Sharon Coleman, Praemi Perera, Janet Fisher, Terry Hoy, Denise White, Alan K Burnett and Seah H Lim. Department of Haematology, University of Wales College of Medicine, Heath Park, Cardiff. Permrbment of the normal T-cell repertoire occurs when an individual is challenged with specific T-cell immunogens. The resultant changes in the T-cell repertoire can be either in the form of clonal expansion or deletion, depending on the nature of the immunogen. Analysis of the TCR VD repertoire can therefore provide useful and important information on the immunogenic effects of any turnour cells or protein molecules on Tlymphocytes. We have used a set of VD family-spedc primers in RTPCR to analyse the TCR VD usage by T-cells in the peripheral blood of seven patients with CML of various disease status. In four normal controls, all the 24 major V@ families were fully represented in the T-cell repertoire. In contrast, we observed varying degrees of absence of certain TCR VD families (ranging !?om 2 to 8 of the 24 major families) in the peripheral blood MNC from all 7 CML patients. The abnormality affected particularly T-cells bearing VP 17 and 8. The relatively restricted T-cell VD repertoire was not due to the involvement of T-cells in the leukaemic process since these T-cells were cytogenetidy normal. Our finding therefore suggests a 'superantigen' phenomenon associated with CML. In the absence of any peripheral lymphocytosis, we suggest that specific TCR VD family-bearing T-cell deletion resulted. There was no obvious correlation between the degrees of T-cell deletion and disease status. Neither was there any correlation observed with the types of bcrabl transcripts of the disease. Further works are therefore ongoing to determine the origin and the nature of this 'superantigen' phenomenon. HARVESTING PERIPHERAL BLOOD STEM CELLS AFTER 40 MYELOSUPPRESSIVE CHEMOTHERAPY IN CHRONIC MYELOID LEUKAEMIA. R Powlq, GJ Mufti*, J Mehta, A Pagliuca*, A Mijovic', J Swansbury, B Czepulkowski*, S Singhal, J Treleaven. Royal Marsden Hospital, Surrey, and *King's College Hospital, London. Leukapheresis during hematologic recovery from myelosuppressive chemotherapy has been used to obtain Philadelphia-negative (Ph-) cells in patients with chronic myeloid leukaemia (CML). 10 patients (16-71 years, median 43.51 with Ph+ CML received ICE chemotherapy (idarubicin 6 mg/m x 3-5 d, cytarabine 200 mg/m2 x 5 d, and VP-16 150 mg/m2 x 3 d) followed by G-CSF. 6 were in first chronic phase (CP), 2 in second CP after lymphoid blast crises, and 2 in accelerated phase. 2-6 aphereses (median 3, total 36) were performed starting at 926 days $median 14.5) after ICE when the total leukocyte count was 0.64.7 x 10 /L (median 1.2). The leukoc te levels at which apheresis was initiated at the two centers were signikantly (P=.Ol) different: 1.4-4.7 (median 3.3) at King's, and 0.6-1.0 (median 0.7) at Marsden. The total cell ields were 1.3-3.6 x 10' mononuclear cells/kg (median 2.8) and 0.3-85.1 x 106 CD34+ cells/kg (7 patients evaluated; median 9.8). Of the 33 harvests evaluated cytogenetically, 5 showed no metaphases. 7% Phmetaphases 100 >50 <50 None Total Individual harvests 7 5 7 9 2 8 Individual patients 3 1 5 1 10 All 3 patients with 100% Phcollections were in first CP 2, 7 and 26 months from diagnosis. The patient with >50% Phcells was in first CP 32 months after diagnosis, whereas cytogenetic response was poor in the 2 first CP patients harvested at 60 and 95 months and in the 4 patients harvested be ond first CP. The absolute neutrophil count remained <0.5 x 109/L for l 4 4 days (median 15.5) following ICE. 4 patients (3 Ph-) have so far been autografted after 16 mg/kg busulfan (n=2) or 200 mg/m2 melphalan (n=2). 1 of the 3 patients receiving Phcells died of graft failure, and 2 are alive with 93% and 100% Phcells at 11 and 5 months respectively on interferon-a. We conclude that (1) it is possible to harvest Phcells after ICE in some CML patients, (2) the extent of negativity depends upon the stage of the disease and time from


With a massive increase in user device heterogeneity, an effective distribution of live video streaming that takes into consideration varying display sizes and processing capabilities of end user devices is becoming a necessity for live multimedia content providers worldwide. In order to answer the challenges of device heterogeneity, an underlying delivery architecture needs to be enhanced so that the best possible quality of video is delivered to the end user in accordance with the end users' device capabilities in a timely and effective fashion. In a primitive video streaming environment that does not take device heterogeneity into consideration, video streaming is based on a single-layered video which uses a scheduling algorithm that ensures timely download of video chunks (i.e. chunks are downloaded before they need to be played back). This paper introduces a model for chunk scheduling algorithm which examines the issue of live video streaming performance optimization as a knapsack NP-hard problem. The proposed scheduling algorithm uses a taboo search method to identify and prioritize chunk delivery in addition to taking bandwidth throughput and delivery ratio into consideration. It optimizes bandwidth utilization by identification of "useless available chunks" by identifying them via chunk playback deadline. With this approach, chunks whose playback deadline has passed as well as those who belong to layers that do not have corresponding lower values will be considered as useless and will be disposed of. Finally, this paper provides simulation results which show that the proposed algorithm significantly performs better than the `primitive' chunk scheduling strategies especially in situations with rigid bandwidth constraints.


The effect of thyroid hormone on the secretion of human growth hormone (HGH) was assessed by radioimmunoassay in patients with thyroid disorders and in normal males treated with triiodothyronine (T3), prednisolone (CS) and both drugs. To provoke the release of HGH, two tests; ITT(intravenous injection of 0.1 U./kg b.w. of crystalline insulin) and ATT (infusion of 0,5 g/kg b.w. of 1-arginine monohydrochioride over a 30-minute period), were employed. To induce a state of factitious hyperthyroidism ,150 pg/d. of T3 were administered for 10 days in normal males, and plasma HGH responses to arginine were evaluated before and after the treatment in comparison with the results obtained by the same studies with prednisolone ((30 mg/d.) and prednisolone plus T3. Results were as follows: 1) In 8 patients with primary hypothyroidism and 11 thyrotoxic patients, the mean max. levels of HGH in ITT were 3.3, 6.7 mpg/ml, respectively, and were significantly lower compared with 14.6 mpg/m1 in normal controls. No significant difference was observed in the degree of insulin-induced decrease of blood sugar between the patients and normal controls. In 11 patients with hypothyroidism and 16 thyrotoxic patients, the mean max. levels of HGH in ATT were 3.2, 8.1 mpg/ml, respectively, and were also significantly lower compared with 18.6 mpg/ml in normal controls. When euthyroid states were brought about with treatment in both hypothyroidism and hyperthyroidism, the HGH responses to arginine improved to the mean max. levels 14.2, 13.9 mpg/ml, respectively, but these values were still considerably lower than those in normal controls. Five thyrotoxic patients with glucose intolerance showed higher response to insulin-induced hypoglycemia and lower one to arginine than the thyrotoxics with normal glucose tolerance. 2) In thyrotoxic patients, max. level and max. increment of HGH in ITT and ATT were not correlated with serum thyroxine levels, degree of clinical severity, and duration of the illness and other laboratory data. 3) After treatment with T3 in 11 male subjects, the mean max. level and mean max. increment of HGH response to arginine were significantly suppressed (p<0.01), being 61% and 64% of those in control studies, respectively. On CS administration, the same degree of suppressive effect on HGH responses to arginine was demonstrated. The combined administration of T3 and CS showed the most suppressive effect on


Inducible nitric oxide synthase (iNOS) and TGF‐β were localized by immunocytochemistry in skin lesions from patients across the leprosy spectrum, and from patients undergoing reversal reaction. iNOS expression was highest at the tuberculoid pole of the spectrum, and increased during reversal reaction. TGF‐β was observed throughout the leprosy spectrum, but was highest at the lepromatous pole. Levels of TGF‐β decreased during reversal reaction. Reduced levels of TGF‐β may contribute to unregulated inflammatory responses during reactional episodes.


The article discusses the calculation methods of thin plates by applying them to the barge hull. Some existing methods and their comparison are considered. An improved calculation method of the plates with variable stiffness is proposed. When using such method, it is not required to divide the construction into separate homogeneous parts and support the performance of kinematic and static conditions of the matching points of the neighbouring parts of the construction. Moreover, in contrast with other methods, the proposed method is independent by the boundary conditions. Some experiments for the plates with variable thicknesses under distributed load are made. In addition, FEM analyses are carried out. The results show a good correlation to the theoretical calculation.


This study sought to investigate the association of light physical activity (LPA), moderate-to-vigorous physical activity (MVPA), sedentary time (SED), and sleep with lung function in children and adults with CF. In total, 86 children (41 females; 13.6 ± 2.8 years; FEV1%predicted: 86 ± 1%) and 43 adults (21 females; 24.6 ± 4.7 years; FEV1%predicted: 63 ± 21%) with CF participated in this study. Wrist-worn accelerometery was used to assess PA, SED and sleep. Compositional linear regression models were conducted following normalisation via isometric log-ratio transformations. Sequential binary partitioning was applied to investigate the impact of reallocating 10 to 30 min between each behaviour on FEV1%predicted. A decline in FEV1%predicted was predicted with the reallocation of 30 min from MVPA to SED or LPA or sleep to any other behaviour in children (−3.04–−0.005%) and adults (−3.58–−0.005%). Conversely, improvements in FEV1%predicted were predicted when 30 min was reallocated to MVPA from LPA or SED in children (0.12–1.59%) and adults (0.77–2.10%), or when 30 min was reallocated to sleep from any other behaviour in both children (0.23–2.56%) and adults (1.08–3.58%). This study supports the importance of MVPA and sleep for maintaining and promoting lung function in people with CF.


Friction is the force resisting relative motions between two bodies, it causes cycle oscillations and impairs closedloop tracking performance for robot manipulators. To address this problem, in this paper, we propose a neural network (NN) structure with attention mechanism, which compromises the calculate efficiency and accuracy. In this structure, both instantaneous data and feature abstracted from historical data are utilized as inputs, and the torques needed to compensate for the effects of friction of each joint are the targets. Besides, the proposed NN method are contrasted with XGBoost method and convolutional neural network method to demonstrate that NN can achieve better approximation performance in offline experiment. Training data are collected by traversing through the working velocity of robot joints on the task trajectory, based on which the best model will be produced and is deployed on servo controller of a 6-degree-of-freedom (DoF) robot manipulator. Finally, the NN structure is tested on a real robot manipulator for online validation, the robot manipulator is programmed to run on the same trajectory with random speeds for a period of time. Online experiment results show that the predicted compensating torques applied to robot by adding feedforward control to the current command are always closer to the desired torques, and tracking errors of joints are effectively reduced.


This paper describes a robust technique to map HRAM lineaments using wavelet transform analysis and skeletonization. This technique is completely automated and therefore much faster, more cost-effective, and less subjective than traditional approaches to mapping lineaments. Preliminary results are very encouraging and reveal lineament that are likely to be missed using traditional lineament mapping techniques.


Orodispersible film is fast growing drug delivery and offers advantages over conventional oral dosage forms, therefore can be used as an alternative to conventional dosage form. Orodispersible films are convenient to swallow, self-administrable, rapidly hydrates, disintegrates and dissolves in the oral cavity or buccal cavity which makes it a versatile platform for drug delivery. The design of adequate orodispersible films requires comprehensive expertise of pharmaceutical properties of drug and polymers along with a commendable selection of manufacturing process. The aim of this review is to provide marketing advantages of orodispersible film over conventional dosage forms and their formulation composition, manufacturing techniques and their different patented technological platform that has already in the market, manufactured by various distributors and their salient features.