In this short note we give an introduction to some elementary properties of Cayley graphs.The first section covers the definition and gives some basic illustrative examples. Section 2 describes what it means to refer to a collection of finite groups as a family of expanders. The key result of that section shows that families of abelian groups are not good expanders. This helps gives context to the recent remarkable results about the expansion of families of simple groups. The third section connects eigenvalues of a Cayley graph to representation theory, with a view towards Xander's talk. While preparing this note we have followed chapter 11 of the paper [HLW06]. Definition 1.1. Let H be a finite group and let S ⊆ H be a subset. The corresponding Cayley graph C(H, S) has vertex set equal to H. Two vertices g, h ∈ H are joined by a directed edge from g to h if and only if there exists s ∈ S such that g = sh. Each edge is labeled to denote that it corresponds to s ∈ S. If G is a graph such that there exists a group H and generating set S ⊆ H with G ∼ = C(H, S), then G is said to be Cayley. However, the edge labelings are necessary for this uniqueness statement to hold. are isomorphic, but they are distinguished via the labels. In what follows we are concerned with using group theoretic methods to construct expander graphs, so we don't really care about all the extra structure that comes with a Cayley graph. We will thus take our sets S ⊆ H to satisfy the following properties: (1) they will be generating sets, so that C(H, S) is a connected graph; (2) we will usually consider symmetric sets, that is, sets which satisfy S = S −1. Under this assumption we may treat C(H, S) as an undirected graph; (3) always assume that S does not contain the identity, so that C(H, S) does not contain any loops. Under these assumptions note that C(H, S) is a connected and undirected regular graph of degree |S| on |H| vertices (without loops). Inside a single group one can often find different sets of generators with the same numbers of elements, but such that the corresponding Cayley graphs are not iso-morhic. For a striking example of this phenomenon one can consult the paper …


Nowadays, the difficulties of communication, relationship, and mostly building up strategies of cooperation between schools and families are issues of great interest. The relationship between parents and teachers is often affected by conflicts of interests, causing embarrassing situations between them. We believe that school is responsible of becoming closer to families, while developing a pleasant learning atmosphere for students. This only would be possible if it is based on the complete knowledge of the student's families. We want to divulgate the results of a research that took place at elementary schools, in which we built an instrument to observe and analyse of the educational relationship that will allow us to validate the Theoretical Explicable Model. We assumed that the class' tutor work influences the knowledge that the school has of the students' families and develops the relationship between schools and families.


Gestational diabetes mellitus (GDM) is a metabolic disorder whose major pathophysiological basis is demonstrated as placental insulin resistance (IR), while Smad4 always functions in the signal transduction of transforming growth factor beta (TGF‐β) pathway. Our study aims to figure out the role of Smad4 in an insulin resistance (IR) cellular model using placental trophoblast cell line. Importantly, HTR8‐Svneo cells, in the status of IR, indicated a significant increase in the expression of Smad4. Subsequently, the HTR8‐Svneo cell line with up‐regulated or depleted Smad4 was respectively achieved by the effective over‐expressed plasmid or siRNA of Smad4. We found out that the deficiency of Smad4 could promote the insulin sensitivity and restrict the inflammatory response in IR group of cells with significant augment in glucose uptake, up‐regulation of insulin signalling‐related molecules and attenuation in inflammatory biomarker expressions. On the contrary, the over‐expression of Smad4 showed a reversal effect on these alterations in IR group of cells. Besides, the positive effect of Smad4 on cell viability was also observed in our study.


In recent years, Vehicular Cloud Computing (VCC) has emerged as new technology to provide uninterrupted information to the vehicles from anywhere, anytime. The VCC provides two types of services such as safety related messages and non-safety related messages to the users. The vehicles have less computational power, storage etc. so that the vehicles collect information and send these information to the local or vehicular cloud for computation or storage purposes. But due to the dynamic nature, rapid topology changes and open communication medium, the information can be altered so that it leads to misguiding users, wrong information sharing etc. In the proposed scheme, Elliptic Curve Cryptography used for secure communication in the network that also ensures the security requirements such as confidentiality, integrity, privacy etc. The proposed scheme ensures the mutual authentication of both sender and receiver that wants to communicate. The scheme uses additional operation such as one-way hash function and concatenation to secure the network against various attacks i.e. spoofing attack, man-in-the-middle attack, replay attack etc. The effectiveness of the proposed scheme is evaluated using the different metrics such as packet delivery ratio, throughput and end-to-end delay and it is found better where it is not applied.


The paper reviews how recent marketing concepts reflect sustainability requirements and competitive advantages of their integration into mission, strategy and policies at companies. Marketing approach of sustainability is discussed through the concepts of added value delivery to customers, societal marketing and customer relationship marketing. The discussion is extended to some related strategic and management implications as well.


I shared Raanan Gillon's1 surprise at Robert Veatch's criticism of the white coat ceremonies,2 and I think that the points raised by Veatch were quite adequately countered by Gillon's response. The provocative points raised by Veatch do stimulate some valuable critical thinking about the process, although I think Veatch was carried away a bit by hyperbole. To label the drama of the ceremony as "ominous" goes a bit far by any criterion.

I should like to describe an oath taking initiation ceremony in use at the Ben Gurion University Faculty of Health Sciences for almost three decades, its history, features, current practice, and conclusions. I believe that Veatch's specific objections are addressed by our process and merit consideration by other institutions as well.

When the medical school was founded in 1974 the then dean (and university president as well), Professor Moshe Prywes, met with the just entering class several weeks before the onset of the academic year during a summer preliminary orientation period (of several weeks duration). Professor Prywes, an imaginative, charismatic innovator with a flair for public relations and the dramatic, suggested to the entering class that they take the physician's oath during the first weeks of the academic year, coinciding with their first exposure to patients (the programme provided for one clinical day each week from the very first week of studies—then an unusual curricular innovation). He explained that he wanted the students to regard themselves as already bearing responsibilities and duties, and not just rights. He saw them as "change agents" working to upgrade the medical care and the health of the patients and community, right from the first days of their schooling.

I had just arrived in Israel as a new immigrant to assume the foundation professorship of medicine, coming from …


Euthanasia is a problem hotly debated for a long time,which has been puzzling both the academic circles and judicial circles.This text attempts,in terms of the penology,to make a preliminary analysis toward the legalization of euthanasia,from the following three aspects as the principle of legality,the criminal substantive characteristic and the comparison between euthanasia and intentional killing.


The proposed research is a didactic sequence for the use of cultural wealth and the variety of tourist sites in the historic area of La Candelaria, aimed at the development of activities that facilitate the acquisition of the lexicon from the exploration of real environments.
The teaching sequence is divided into three sessions with visits to Casa Museo del Florero, Casa Museo del Marques de San Jorge and Quinta de Bolivar, starting from Bolivar Square. From there the possible routes to reach each of the selected places are proposed. In each of the activity guides will be presented the contents, skills and expected accomplishments, as well as some indications for teachers and companions of each of the outputs.


Development of new null detectors and the advent of cheap computer power have brought improvements in ac/dc transfer measurements. It has been found that almost all commercial resistors show anomalous frequency responses at high voltages. Techniques for the selection of the best devices and new resistor mountings are described.


L10 FePt nanostructures were chemically synthesized. The as-made material revealed a 1.4 kOe coercive field, without a postannealing procedure. Addition of Au resulted in the increase of the fct phase and the complete elimination of Fe-oxides, leading to a material with up to 5.8 kOe coercivity at room temperature. The particles synthesized in the presence of pluronic-F127 are spherical with ∼8.7 nm diameter, whereas the particles synthesized in the presence of oleic acid and PVP have a wormlike shape and are less than 5 nm in width.


Summary Introduction. The number of adults with cystic fibrosis (CF) is gradually increasing. The nutritional status has an important role in the progression of the disease. Aim. To investigate the malnutrition risk and the nutritional status of adults with CF, and to analyse the obtained data according to gender, transplantation, dominantly affected system organ class, comorbidity, bacterial infection and sports habits. Material and methods. The nutritional status was assessed by a bioelectrical impedance machine, and the malnutrition risk screening was measured by NRS2002. Results. Forty-four patients participated (20 males, 24 females). Mean BMI in males was significantly higher compared with females (p = 0.01). The mean muscle percentage of patients doing sport regularly was significantly higher than those who do not do sport (p = 0.0126). Between mean body fat percentages there was no significant difference. There was no significant difference in mean BMI and body fat percentage between patients with and without transplantation, patients who live with one dominantly affected system organ class and patients who live with more dominantly affected system organ classes, patients who have concomitant illness and patients who do not, or patients who have one concomitant illness and patients who have more concomitant illnesses. Moreover, there was no significant difference in mean BMI and body fat percentage between patients who suffer from a bacterial infection and who do not, or patients who suffer from one bacterial infection and patients who have several bacterial infections. The majority of those patients who participated in the malnutrition risk screening were malnour- ished (77.3%). Conclusions. The research can prove high prevalence of malnutrition among adult patients with CF, which needs nutrition intervention to recover from.


Scrapie-induced amyloid plaque formation in mouse is very useful animal model in research of human Alzheimer's disease. It has been suggested that sulfated glycoprotein-2 (SGP-2) is involved in neuronal cell death. In this study, we have investigated the role of SGP-2 in formation of amyloid plaques in brains of IM rnouse infected with 87V scrapie agent. Both control and scrapie-injected mice were sacrificed after 300 days incubation period and total cellular RNAs were extracted from cerebral cortex, brain stem, cerebellum and entire brain. Northern blot analysis showed that SGP-2 mRNA label was significantly increased in brains of scrapie-infected mice than in control mice. In dissected tissue samples, the level of SGP-2 mRNA was elevated in cerebellum and brain stem but not in cerebral cortex. Since amyloid plaques were mainly found in cerebral cortex of scrapie-injected mice, the observed changes of SGP-2 mRNA level were not exactly correlated with the site of amyloid plaque formation. It has previously shown that SGP-2 mRNA levels were also increased in several nonneural tissues under going programmed cell death and in some tissues of neuronal degeneration. We speculate that the overall increase of SGP-2 mRNA levels in brains of scrapie-infected mice may be a compensatory response to a neurodegenerative cascade control.


This research tries to explain incest in the Polahi tribal tribe, who dwell among the interior woods of Gorontalo, more specifically in the forests of the Boliyohuto region, Tamaila Village, Tolangohula District, Gorontalo Regency, a culture that is deeply rooted in the local population. The research technique employed is prescriptive and applied normative legal research. Primary and secondary legal documents, as well as literary and document studies, were utilised as sources of legal materials. In the Polahi tribe, inbreeding occurs when a person reaches maturity (both male and female) and is matched with their own siblings. Inbreeding is illegal in marriage, according to the conclusions of this research, under Law Number 16 of 2019 about Amendments to Law Number 1 of 1974 Concerning Marriage, which stipulates that marriage is prohibited between two persons connected by blood, breast milk, and marriage. As a result, the Polahi Tribe has been found to have broken Article 8 of the Marriage Law. If the husband and wife knew before they married that inbreeding was banned by law or religion, the marriage would be considered illegal, and the child's status would be void. As a result, the kid that is born only has a favourable position in terms of inheriting and supporting the original mother and her family. Meanwhile, the government, in this instance the Gorontalo Regency Government, is working to eliminate the practise of inbreeding within the Polahi Tribe's customary law group. The situation of children born from incestuous marriages because their parents were unaware that their union broke the marriage restriction is still relevant. In the meanwhile, if both parties are aware that the marriage is prohibited under Shari'a, the marriage must be cancelled. If they do not end the marriage, it becomes a legal marriage, and the child's status becomes invalid. As a consequence, children that are born are only in a better position to inherit and support their birth mother and family.


Hangul (Korean characters) used by Koreans is one of the most scientific and amazing letters in the world. It was first created to enable easy and convenient use of the language for the nation. Also, along with popularity of Korean Wave, the number of foreigners interested in and wanting to study Korean language is increasing as well. When resonance frequency of allophone words selected from Korean and English individually are compared, it was found out that English natives have a difficulty in allophone as they recognize each letter differently.


A 5-month sample of geomagnetic micropulsation data from Strawberry Hill, Massachusetts, +54° geomagnetic latitude, is analyzed in octave period bandwidths in the 0.5 to 1024-s period range. Hourly average amplitudes of the horizontal and vertical components are used as measures of the activity. The auroral oval (AO) regime of micropulsations is identified by large H and Z amplitudes combined with small H/Z ratios. It is observed during large nighttime disturbances within a 'micropulsation oval' whose southern boundary extends 1° or 2° of latitude south of the oval delineated by particle precipitation and is attributed to hydromagnetic waves which propagate in the guided mode from the plasma sheet in the magnetospheric tail. Spatial variations of the source strength in the plasma sheet, which vary with micropulsation period, are reflected in the diurnal variations of the AO amplitudes.


: This creative writing research takes as its basis both the plurality of time and the plurality of queerness and attempts to locate a hybrid form that allows six creative writers to explore the relationship between their individual practices and time: bringing them together into a reflexive space that allows them to be read together while holding them apart. By investigating an area of making and thinking composed of individual strategies, questions, challenges, contradictions, problems, logics, the writers discover in, first, the discrete space of the case study and, second, the critical space of the collaborative essay that queerness and time may meet on the shared ground of form; that form is a site for both creative and political/representational activity; and that a multiplicity of times and spaces, particular to each researcher and articulated specifically here, is not just the medium in which the work is made but fundamental to its content, elaboration, potentiality, and reception. George Haddad is a doctoral candidate at the Writing and Society Research Centre, Western Sydney University. His Novella Populate and Perish (2016) was the recipient of the Viva La Novella prize and his short story Kátharsis was awarded the 2018 Neilma Sidney Prize. Dr Ann Lee is a Playwright and Independent scholar with a PhD in Southeast Asian studies from the National University of Singapore. She is currently writing a book on political humour and satire in Indonesia and Malaysia. Her published work includes 'Tarap Man' in Southeast Asian plays (Aurora Metro, 2016) and an anthology of her work for the stage, Sex, Stage and State: Kuali Works plays (Parama Adhi Perkasa, 2011).


The automatic arug infusion system using self-tuning adaptive controller of blood pressure based on microcomputer is proposed to control the increase and decrease of the Mean Arterial Blood Pressure (MABP) in rabbits. The self-tuning minimum variance adaptive controller uses a second order autoregressive moving average (Am) model of the dynamic system response to a pharmacological agent. The parameters of model are estimated by using on line recursive least squares algorithms. The experimental results indicated that automatic drug infusion system using self-tuning adaptive controller of blood pressure is applicable to clinical situations.


To investigate a novel Hadamard‐encoded spectral editing scheme and evaluate its performance in simultaneously quantifying N‐acetyl aspartate (NAA) and N‐acetyl aspartyl glutamate (NAAG) at 3 Tesla.


Abstract The engineering characteristics of two types of pulverized fuel ash (PFA) are investigated in terms of their geotechnical properties. The two PFAs investigated are (1) a 'lagoon' PFA, subsequently stockpiled and then end-tipped for infilling an old gravel pit in Staffordshire, and (2) a 'conditioned' PFA used to create a mound adjacent to a coal power station in Yorkshire. Measurements of strength and compressibility characteristics are discussed with respect to predicting the behaviour of these two PFAs vis-à-vis slope stability and settlement. Charts are presented (a) for determining settlements of lagoon PFAs, and (b) for establishing strength parameters of conditioned PFAs.


We reveal the existence of a new types of surface electromagnetic waves supported by hyperbolic metasurface, described by a local diagonal anisotropic conductivity tensor. We present a comprehensive analysis of the dispersion and the equal frequency contours of surface waves propagating along hyperbolic metasurface. We demonstrate that the spectrum of the hyperbolic metasurface waves consists of two branches corresponding to hybrid transverse electric-transverse magnetic waves with a polarization that varies from linear to elliptic or circular depending on the wave frequency and propagation direction.


Some granulites from the Amessmessa area (south In Ouzzal unit, Hoggar) contain the peak assemblage gedrite+garnet+sillimanite+quartz that was used to estimate the P-T conditions of metamorphism. The rocks developed symplectites and corona textures by the breakdown of the primary paragenesis to orthopyroxene, cordierite and spinel. The successive parageneses formed in separate microdomains according to a clockwise P-T path. Geothermometry, geobarometry and phase diagram calculations indicate that the textures formed by decompression and cooling from 7-9 kbar and 850-900° Ct o 3.5-4.5 kbar and 700-800°C. This P-T evolution is consistent with low to medium a H2O , between 0.4 and 0.7, and is similar to the metamorphic conditions deduced in Al-Mg granulites from the north of In Ouzzal.


Abstract The reaction of thiosulfinates with amine salts of aryl sulfinic acids has been examined for the preparation of thiosulfonates, particularly unsymmetrical derivatives.


Didenko A.V. 2013. Gobiids of the Dniprodzerzhynsk Reservoir (Dnieper River, Ukraine): distribution and habitat preferences. Acta Ichthyol. Piscat. 43 (4): 257–266. Background. The Dniprodzerzhynsk reservoir is one of six reservoirs built on the Dnieper River, which currently supports important commercial and recreational fisheries. To date, there are no published data on the reservoir's non-commercial fish species, among which gobies are considered to be the most abundant and important species. The goal of this work was to contribute to general knowledge on local gobiid fauna, focusing on their mesohabitat preferences. Materials and methods. Sampling in the Dniprodzerzhynsk reservoir was conducted during late August of 2011 and 2012 within the framework of routine annual juvenile fish surveys in the Dnieper reservoirs. Fish were collected at sampling sites located along the reservoir shoreline using a beach seine made of mill sieving gauze (1 mm mesh size). Mesohabitat features were recorded at each beach seine haul site, and included maximum depth, substrate type, and vegetation density. These data were used to identify fish mesohabitat preferences with the aid of Ivlev's electivity index. Results. Seven gobiid species were collected: western tubenose goby, Proterorhinus semilunaris (Heckel, 1837); knout goby, Mesogobius batrachocephalus (Pallas, 1814); Pontian monkey goby, Neogobius fluviatilis (Pallas, 1814); round goby, N. melanostomus (Pallas, 1814); racer goby, Babka gymnotrachelus (Kessler, 1857); Pontian bighead goby, Ponticola kessleri (Gunter, 1861); and ratan goby, Ponticola ratan (von Nordmann, 1840). Ratan goby was recorded for the first time from this reservoir. Most frequently encountered were monkey goby (76.27%), followed by western tubenose goby (32.20%), racer goby (31.36%), round goby (14.41%), bighead goby (10.17%), while knout and ratan gobies were the most rare (each accounting for 1.69%). All gobiids showed preferences for certain mesohabitat features such as bottom substrate and aquatic vegetation density. Conclusion. The gobiid fauna of the reservoir is rich and is dominated by monkey goby. The occurrence of ratan goby, an estuarine and marine species that adapted to freshwater conditions, is an evidence for ongoing PontoCaspian gobiid invasion to the Dnieper reservoirs.


A high-speed uplink packet access (HSUPA) scheme and improved. Optimized rate (RATE) service request reporting and signaling for low-delay transmission service, and the three main aspect to provide a MAC-e PDU format for a control information signaling for a low-delay transmission (signaling for lower delay delivery) is considered as a major improvement remaining two perspectives can be considered a minor improvement. High speed uplink packet access, signaling provided


In this paper the electromagnetic force between two parallel electric currents, carried by thin conductors in the close vicinity of each other, is calculated. This is done by using Coulomb's Law instead of Lorentz' Force Law. The success was possible thanks to the rigorous analysis of the propagation delay, due to moving electrons, and the application of the length contraction according to the Special Relativity Theory. In the calculations, also the necessary feeding back of the electric currents back to their origin is taken into account. However, only the parts of the circuit, where the two currents are in close vicinity, contribute substantially to the mutual force. The result of the calculations is that the force between two parallel currents, carried by thin conductors, obeys the inverse square law, exactly as the Lorentz Force Law does. There is one important difference: The coupling constant is slightly smaller. This indicates that the currents must be correspondingly larger than expected when using Lorentz' Force Law. Another consequence of the new theory is that the spatial dependence of the electromagnetic forces displays a different shape.


A basic question in glass science concerns the nature of the glass transition and, while this process is intimately related to the dynamical properties of a system on cooling [1], it is nevertheless important to understand the atomic ordering in the liquid and glass. Within the family of binary network glass forming systems, ZnCl2 is an exemplar whose basic properties can be understood in terms of an ionic interaction model, provided that anion polarisation effects are taken into account, i.e. it is possible to model this material by using large scale molecular dynamics methods [2]. We have therefore applied a combination of neutron and X-ray diffraction techniques to measure the full set of partial structure factors for liquid and glassy ZnCl2, thus maximising the information that can be obtained at the pair correlation function level [3,4]. The neutron diffraction experiments employed the method of isotope substitution and were made using the instrument D4c at the Institut Laue-Langevin in Grenoble, France. The high energy X-ray diffraction experiments used beamline BL04B2 at SPring-8 with an incident wavelength of 0.2 Å. The sample for the X-ray experiments was held in a silica capillary tube which was loaded by using the "Hummingbird" method in which anhydrous beads of ZnCl2 are first sealed under vacuum in a silica tube connected to the capillary (Fig. 1). The beads are then evaporated in an oven, condensed into a liquid within the capillary, and quenched to form a glass. The capillary containing the sample is finally sealed under vacuum. The full set of partial structure factors were extracted from the neutron diffraction data sets by using the method of singular value decomposition [4]. Their accuracy was assessed by using them to reconstruct the expected X-ray diffraction pattern, making a correction for the effect of the resolution function of the neutron diffractometer [5]. A comparison between the measured and reconstructed X-ray diffraction patterns for liquid and glassy ZnCl2 is shown in Fig. 2. The diffraction patterns were used to construct three-dimensional models (Fig. 3) for liquid and glassy ZnCl2 by employing the reverse Monte Carlo (RMC) method [4]. The results show that the predominant structural motif in both phases is the corner sharing ZnCl4 tetrahedron where the average


Collected quantity,density of semen and amounts of frozen semen were compared on these bulls of different breeds,The experimental results showed that Fleckvieh had significant difference(P0.05) Montbeliate on the collected quantity and amounts of frozen semen,and had no significant difference(P0.05) on the density of semen of them;Fleckvieh and Luxi yellow cattle had no significant difference(P0.05) on the collected quantity,density of semen and amounts of frozen semen;Montbeliate and Luxi yellow cattle were siginificantly different(P0.05)to the collected quantity of semen,but other indexes of them had no ssignificant difference(P0.05);Fleckvieh had no significant difference(P0.05) in the energy before or after frozen of semen and rate of semen abandon of Montbeliate and Luxi yellow cattle.It was concluded that semen's throughput of Fleckvieh bull corresponds with that of Luxi yellow cattle bull,and that of Montbeliate was best of them.


The continuing growth of point-to-point microwave communications has resulted in many new applications which require differing performance characteristics. As the amount of information entrusted to microwave grows, the need for operating reliability becomes much greater. This paper describes a new transistorized microwave system which meets these requirements, and discusses the design approaches used. The system is unusually flexible and embodies many design innovations which result in greatly improved performance.


Understanding the causes, effects and geographic patterns of local hazards is important for helping individuals make educated decisions about how to respond to their threat. Unfortunately, it is often difficult to find comprehensive sources of information about local hazards. In this paper, we discuss the development of an online hazards atlas for the state of South Carolina. We have designed this atlas to facilitate awareness about the causes and effects of hazards. An effective method for communicating this information is through education and awareness programs for children, so we have designed this atlas primarily as an educational tool for K-12 students. However, we have also structured the atlas to ensure that it provides details of interest to the general population. In this paper, we focus on educational, methodological and technical aspects of development of the online hazards atlas to highlight both the benefits and challenges of this type of product and to emphasize where it fits as a tool for improving hazards education. In addressing these issues, we present a model that can be adapted for use in other geographic areas.


The 21st Century Cures Act was signed into law in December 2016. Praised by its advocates as a means of speeding drug development, the act covers several areas, but the provisions related to the US Food and Drug Administration (FDA) will be among the most problematic and potentially important. An earlier version was passed with a wide margin by the House of Representatives in July 2015; it contained sweeping measures to permit manufacturers to submit less rigorous data to the FDA for approval of drugs and devices, and it recommended annual increases to the National Institutes of Health (NIH) budget of approximately 3% per year for 3 years as well as approximately $8.75 billion over 5 years in additional support.1 Further progress on the bill stalled for about a year until it was taken up again in the congressional session after the recent election.


Xanthine oxidase (XO) is a rate limiting enzyme for production of uric acid. The activity of XO in plasma is reported to elevate in patients with familial hypercholesterolaemia and cardiovascular diseases. Such an increase in plasma XO activity was also demonstrated in patients with a variety of cancers. However, there have been few reports evaluating the plasma XO activity in patients with hematological malignancies during course of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and chemotherapies. We explored the relationship between plasma XO activity and clinical symptoms/biochemical parameters in 10 patients with hematological malignancies. The XO activity was measured by a high-sensitivity fluorescence technique. Plasma XO activity in hematological malignancies before chemotherapy was not elevated compared to healthy subjects. In patients receiving allo-HSCT, no apparent increase in plasma XO activity was observed at the appearance of graft-versus-host disease (GVHD). Noticeably, however, the value of plasma XO activity was closely associated with that of serum level of liver transaminases in the course of allo-HSCT and chemotherapies. To our knowledge, the present study is the first to investigate consecutively the value in plasma XO activity in patients with hematological malignancies. Despite small numbers analyzed, value of plasma XO activity was tightly associated with that of serum level of liver transaminases in the course of allo-HSCT and chemotherapies, suggesting that the value may reflect liver damage related with a variety of therapeutic interventions.


Estuaries face on a lot of difficulties in its own setting specifically when the environmental management systems are concerned. Analysis on the existing management systems indicated that the fragmented management system is one of major barriers to develop an integrated national estuary policy. In particular, the policy barriers between the development-oriented agencies and the environmental protection agencies, and the conflicts between the Ministry of Environment and the Ministry of Maritime Affairs and Fisheries seemed so hard to be resolved without the proper national level coordinating mechanism. Moreover, the current estuary management system turned out not to be effective in dealing between the estuary-specific environmental problems and the associated conflicts among stakeholders. Thus, this situation calls for the developments of both national level coordinating mechanisms and site-specific estuary management systems. As a coordinating mechanism, we suggested the establishments of National Estuary Committee in the Prime Minister's Office on the national-level. Also we proposed a development on the Regional Estuary Management Committee for regional level coordination. In order to support an integrated estuary management, it was also proposed to have a development on the National Estuary Management Plan and on the Estuary Management Implementation Plans. This will cover a widerange of estuary management issues in an integrated perspective. According to the case studies, environmental problems and associated conflicts in the estuary can be managed at the program-level management system which will include the National Estuary Program in USA, Thames Estuary Partnership Program in England and Fraser Estuary Program in Canada. In this respect, we proposed to establish a similar National Estuary Program to solve the facing environmental issues in major estuaries. It could be a few proposed examples the Estuarine Ecosystem Preservation Program in the Han-River Estuary, the Estuarine Circulation Restoration Program in Yongsan-River Estuary and the Salt-water Intrusion Control Program in Sumjin-River Estuary. Four different legalization options were examined to legally support the implementation of the suggested system enhancement, which include the revision and updates on existing laws, enactment of 'Estuary Management Act', enactment of 'Estuary Restoration Act' with revision of existing laws, and enactment of special laws directly applicable to the individual estuary as like '○○ Estuary Management Act'. The second option seems to be favorable because it can fully support the suggested estuarine management system as well as potentially the future management requirements.


Traditionally the voltage vector is defined as zero voltage vector (ZVV) when all power switches are off in direct torque control (DTC) system of brushless DC motor (BLDCM). However the study on the voltage and current of the conducting phase windings shows that the voltage vector is not actually zero by using the traditional ZVV. So it is redefined in this paper according to the definition of ZVV in BLDCM DTC system. The construction method and effectiveness of the New ZVV to reduce the torque ripple was discussed and verified by the experimental results and performance analysis.


Recently constructed gravity solutions with Schrodinger symmetry provide a new example of AdS/CFT-type dualities for the type of non-relativistic field theories relevant to certain cold atom systems. Anastasia Volovich and Congkao Wen use the gravity side to calculate n-point correlation functions of scalar fields by reducing the computation to that in ordinary AdS space via a particular Fourier transform. They also evaluate the relevant integrals for 3- and 4-point functions and show that the results are consistent The full paper: http://www.iiste.org/PDFshare/APTA-PAGENO-320080-324287.pdf


One crucial problem in sensor-based human activity recognition is how to model features that can precisely represent characteristics of a sequence of sensor values. For this, we study a codebook approach that represents the sequence as a distribution of characteristic subsequences. The extensive experiments on different recognition tasks for physical, mental and eye-based activities validate the effectiveness, generality and usability of the codebook approach, where only a few intuitive parameters need to be tuned.


A popular method of classifying adverbs is by looking at what they modify: adjective or verb. Another criterion is whether or not the adverbial expression reflects an attitude of the speaker towards the content of his utterance. Both groups, objective and subjective adverbs, contain large numbers of lexical adverbs, all highly conventionalized. Other groups sharing these properties are adverbs of place and indeterminate adverbials. Adverbial phrases can be formed in several ways: by using an adjective, by drawing from the lexical stock of ready-to-use adverbs, by various forms of suffixation, and by reduplication. Adverbials based on the notions 'with' and 'without' deserve special attention, particularly with respect to possessive expressions. The final section discusses constructions based on kinship terms which do not follow the canonical suffix ordering.


The article is analyzed the features of distance learning and forms of its realization, is devoted to research existing technologies and tools of distance learning, as well as their possible applications in modern education system. Presents the potential for electronic information-educational resources for distance education systems.


Convolution neural networks (CNNs) as one of today's main flavor of deep learning techniques dominate in various image recognition tasks. As the model size of modern CNNs continues to grow, neural network compression techniques have been proposed to prune the redundant neurons and synapses. However, prior techniques disconnect the software neural networks compression and hardware acceleration, which fail to balance multiple design parameters, including sparsity, performance, hardware area cost, and efficiency. More concretely, prior unstructured pruning techniques achieve high sparsity at the expense of extra performance overhead, while prior structured pruning techniques relying on strict sparse patterns lead to low sparsity and extra hardware cost. In this article, we propose OMNI, a framework for accelerating sparse CNNs on hardware accelerators. The innovation of OMNI stems from that it uses hardware amenable on-chip memory partition patterns to seamlessly engage the software CNN model compression and hardware CNN acceleration. To accelerate the compute-intensive convolution kernel, a promising hardware optimization approach is memory partition, which divides the original weight kernels into several groups so that the different hardware processing elements can simultaneously access the weight. We exploit the memory partition patterns including block, cyclic, or hybrid as a means of CNN compression patterns. Our software CNN model compression balances the sparsity across different groups and our hardware accelerator employs hardware parallelization coordinately with the sparse patterns, leading to a desirable compromise between sparsity and performance. We further develop performance models to help the designers to quickly identify the pattern factors subject to an area constraint. Last, we evaluate our design on application specific integrated circuit (ASIC) and field-programmable gate array (FPGA) platform. Experiments demonstrate that OMNI achieves $3.4\times $ – $6.2\times $ speedup for the modern CNNs, over a comparably ideal dense CNN accelerator. OMNI shows $114.7\times $ energy efficiency improvement compared with GPU platform. OMNI is also evaluated on Xilinx ZC706 and ZCU102 FPGA platforms, achieving 41.5 GOP/s and 125.3 GOP/s, respectively.


The article tells about the experience  with rivaroxaban  for the prevention  of stroke and thromboembolism  not involving the central nervous system vessels in patients with non-valvular  atrial fibrillation in a number of clinical cases. The article demonstrates  that rivaroxaban's efficacy and safety in everyday medical practice, in general, meets the expectations resulting from the large controlled ROCKET-AF trial.


The present invention relates to a global navigation satellite system NandFlash bus communication system for implementing a baseband signal, including ARM processor, and a baseband circuit NandFlash bus, the ARM processor through said bus with said NandFlash baseband circuit based baseband data communication, the ARM processor including a CPU, a direct memory access controller and NandFlash bus controller, said CPU through said direct memory access controller, a bus controller and the NandFlash bus of the NandFlash connection, the present invention further relates to a method for the baseband signal based on the communication system implemented in a global navigation satellite system. With this kind of configuration of a GNSS-based systems and methods NandFlash baseband signal communication bus implemented, data transmission speed can be improved, a navigation solution for a large savings in CPU time, be applied to various navigation field or other applications of this method can be applied to large-scale application.


A novel is proved of the real condition of the person. Sometimes it reflects the background from the author of the novel. By the novel, an author can express the idea or feeling that derives from his life. In short, the story in a novel can be portrait of the real condition in a certain time. Here, Richard Wright as the author of the Native Son expressed his idea and his feeling through the writing of the novel. His novel full the message that could be represented his real life condition. This study tries to explore the structural analysis of the character, setting, plot, point of view and style. Here, the writer tries to analyze the characters including the characterization of the major character and the minor character, setting of time and place, plot of the story, point of view, style and theme. This analysis of the structural elements of Native Son is meant to reveal the internal coherence that explains the author's worldview.


SUBTITLE: THE CHAOS IN THE US AIRPORT AND AIRWAY SYSTEM MEANS THAT UNFETTERED COMPETITION AND THE LOWEST FARES MAY HAVE TO BE SACRIFICED


The paper discusses the gate complexity of reversible circuits consisting of NOT, CNOT and 2-CNOT gates. The Shannon gate complexity function $L(n, q)$ for a reversible circuit, implementing a Boolean transformation $f\colon \mathbb Z_2^n \to \mathbb Z_2^n$, is defined as a function of $n$ and the number of additional inputs $q$. The general lower bound $L(n,q) \geq \frac{2^n(n-2)}{3\log_2(n+q)} - \frac{n}{3}$ for the gate complexity of a reversible circuit is proved. An upper bound $L(n,0) \leqslant 3n2^{n+4}(1+o(1)) \mathop / \log_2n$ for the gate complexity of a reversible circuit without additional inputs is proved. An upper bound $L(n,q_0) \lesssim 2^n$ for the gate complexity of a reversible circuit with $q_0 \sim n2^{n-o(n)}$ additional inputs is proved.


Knowledge networks can be defined as social networks that enable the transfer of the knowledge, which is defined as the intellectual product formed as a result of the work of human intelligence, to be transferred to any other means of communication. A knowledge network represents a large number of people, resources and relationships between them, to create the highest value, primarily to accumulate and use knowledge through the process of generating and transmitting knowledge. General structure of knowledge networks; it consists of three basic stages: gathering, organizing and disseminating knowledge. The first step, knowledge collection, institutions and organizations to enter the network structure of the knowledge that is present. The organizing phase is the structuring of irregular and unstructured knowledge in the network structure according to certain standards and recording them regularly in the structure. Knowledge dissemination can be expressed as the transfer of organized knowledge in accordance with user knowledge and needs. The purpose of the training knowledge network is to ensure communication between the student, the teacher and the guide, and to store the knowledge that is formed in a course, to enable the system to be recorded in a systematic way, to disseminate it according to the needs of the users and to update the knowledge. A dynamic website and content management system have been developed for the training knowledge network. The training knowledge network has a flexible structure to support web technologies. By making production, management and publication of knowledge within the framework of specific needs, it provides knowledge network for different problems, producing different and tailored solutions. With the example of education knowledge network, a knowledge network that can be developed according to the innovative knowledge network structure is designed.


Nowadays the increasing consumption of fossil fuel and the increasing pollution drive people to look for clean alternative energy resources, energy storage methods and efficient energy consumption ways. Since high-quality graphene was obtained in 2004, it has attracted much interest. Due to its extraordinary properties, graphene has many potential applications in energy storage and conversion. Herein, we review recent progress of these fields, including applications in energy storage such as supercapacitors and Li-ion batteries, and energy conversion apparatus like fuel cells and solar cells.


Performance appraisal is reinterpreted as a test development task, and the appraiser is examined in terms of how well he/she can utilize ratee information validly in judging performance. Appraisal formats and appraiser training programs are critically evaluated as aids for developing good tests. New directions in format development and training are suggested for increasing appraisal accuracy.


Few of us would bother to read a newspaper report or web page headed "No Cases of Brucellosis in Paris This Month," "U.S. Potato Crop Unaffected by Phytophthora infestans," or "Smallpox Remains Eradicated." That is my answer when I hear scientists complaining about headlines. We simply do not want to read articles about Mount Etna not erupting, ships failing to collide in the Atlantic, or banks not being robbed.


In this paper, the problem of leakage detection and isolation in water distribution networks is addressed applying an optimal sensor placement methodology. The chosen technique is based on structural models and thus it is suitable to handle non-linear and large scale systems. A drawback of this technique arises when costs are assigned uniformly. A main contribution of this paper is the proposal of an iterative methodology that focuses on identifying essential sensors which ultimately leads to an improvement of the optimal search efficiency. The algorithm presented in this work is successfully applied to a District Metered Area (DMA) in the Barcelona water distribution network.


Combination of wheel dehumidification air-conditioning research situation in recent years, this paper introduces several kinds of the runner system form. Analysis of the comparison of the dehumidification wheel in the future development direction and the further development of the key problems need to be solved.


Abstract : This research effort is an attempt by the author to examine the broad area of military support to civil authorities and the potential for a significant demand on Department of Defense (DoD) resources. Since September 11, 2001, our nation has devoted a tremendous amount of effort to place greater emphasis on homeland security. The National Strategy for Homeland Security provides the overarching framework for organizing to secure our homeland. It prescribes various roles for all segments of the nation. It specifies that the DoD contributes through three primary means: military missions overseas, homeland defense, and support to civil authorities. Military support to civil authorities constitutes a very broad area that may place a significant demand on DoD resources and may have a significant impact on DoD's ability to perform its role of homeland defense. In fact, DoD's military support to civil authorities role in support of homeland security has the potential to become a primary mission for DoD in some areas. This gray area between homeland defense and military support to civil authorities require further examination.


Biologists believe that the source of human behaviour resides inside of us and that the differences between males and females can actually be found in our body components such as cell compositions, set up and anatomical parts such as differences in brain seizes (Kimmel 2004). Their explanations on gender and sexuality are based on the visible physical physiological differences. Because they present their explanations as 'indisputable truth' based on 'objective scientific facts' (Hird 2004), they have also become widely acceptable and easy to follow in societies across the globe. This has been so because they are in line with every ones observations on the physical differences of the body between men and women (Kimmel 2004). Biological explanations of gender and sexual differences have been linked to Charles Darwin's work on evolution. His explanations were contrary to commonly accepted cultural and theological explanations of divinely created sexual differences where the different sexes serve particular purposes. On the contrary, Darwin suggested that just as wild animals had physiological differences between the sexes and so did humans. He suggested that woman differed to men in terms of their mental dispositions with men seen as aggressive, competitive, and ambitious and women on the contrary as tender, caring and less selfish. Others have explained this further by asserting that men had 'larger brains' than women (Kimmel 2004).This definition of differences between men and women in this way had serious implications. It led to the exclusion of women from education and public life as arguments that women who aspired to move into public sphere were basically aspiring to do things that their bodies were not designed to do because issues to do with voting, working were then seen as a man's domain (Hird 2004). Others questioned whether women, 'with a small brain,' could undergo training or education and if their bodies could not cope with the amount of pressure that the education gives, coupled with the tremendous pressure that reproduction puts upon their bodies (Beasley 2005; Kimmel 2004). Such explanations were based on observations that college educated women had fewer children, were marrying less than their non college educated counterparts. Such arguments led to assertions that women are weaker than men thus the differences between men and women were natural, due to their sex and they will always be subject to man (Kimmel 2004). Biological arguments about the sex differences have also been political and conservative in nature. They have argued that the social arrangements 'including social, economic, and political discrimination are inevitable outcomes of nature working in its mysterious ways' (Kimmel 2004 pg46). However, what such deterministic explanations cannot explain is if male domination is natural and based on human biological composition, why do women aspire to be lawyers, leaders, army soldiers or police spheres that are considered to be for males if it is not in their biological make up to do such jobs. On the other hand why is male domination over women forceful, reinforced by laws, traditions and customs (Kimmel 2004)? Biological approaches in some research reports argue that they can isolate homosexual gene in the human body. Such studies imply that there is a genetic link to homosexuality while heterosexuality is 'normal' and natural (Hird 2004). Such concepts have also influenced some thoughts among social scientists for example sex role theorists have a biological influence in defining gender (Kimmel 2004). To put simply, biological approaches argue that the distinction between men and women are due to inherent genetic and hormonal differences (Levay 1991) and therefore efforts to bring about equality between men and women will not work because women and men are born differently. The biological perception of gender and sexuality has over the years led to a binary dualism where gender and sexuality are seen as distinct concepts. …


In this paper we propose a low-complexity rate-one multiple-input multiple-output (MIMO) scheme with four transmit antennas and phase feedback. A preprocessor design based on phase feedback information enables the proposed scheme to achieve full diversity order as well as a coding advantage. Signal-to-noise ratio (SNR) analysis is performed and it is used to find the optimal (non-quantized) phases in the sense of maximizing the instantaneous SNR. A quantized feedback analysis of the proposed scheme for quasi-static flat Rayleigh fading channels is also considered. Monte Carlo simulations are performed for different closed-loop space-time block codes with four transmit antennas and unitary transmission rate. Simulation results illustrate that the proposed scheme achieves full diversity order and outperforms other good schemes in terms of coding gain and decoding delay.


The clinical presentation of a neck venous aneurysms, implies a diagnostic challenge due to its rarity. They are presented as neck masses that can easily be confused with other clinical neck entities. Doppler ultrasound technique is the gold standard to confirm its diagnosis. Therapeutic approach varies from surgical resection to watch & wait. We report a clinical case of a 79-year-old woman who came with this vascular defect. Surgical resection was performed and postoperative period runs without complications. 1130-0558/© 2020 SECOM. Publicado por Inspira Network. Este es un artículo Open Access bajo la licencia CC BY-NC-ND (http:// creativecommons.org/licenses/by-nc-nd/4.0/). A R T I C L E I N F O R M AT I O N


Interest in local food systems has increased greatly in the last 20 years. This study sought to understand what motivates customers to purchase local foods, which may be more costly and less convenient to acquire than supermarket fare. I used the life history method to analyze the formation, complexity and interrelationships of motivations behind purchasing local food. This method permitted particular attention to changes in motivations over time. The sample included twelve food customers identified by key informant vendors from one urban farmers' market in Iowa. Using a semi-structured question guide and a drawing exercise, I gathered customers' oral and pictorial accounts of their food histories in face -to -face interviews conducted in the spring of 2001. Local food customers' motivations were a complex weave of moral, philosophical and social dimensions developed over a long period of time through experiences and social interactions. Childhood experiences were often reflected in adult meanings customers attached to local food. Socially engaged European travel, fine dining and educational experiences were additional themes connected to local food by the customers. This study suggests that customer motivations for selecting local foods and maintaining their commitment can be viewed as contributing to a culture of local food. Through social interactions centered on local food, customers and vendors find and create shared patterns of meaning that further constitute a culture of local food.


Multiple sclerosis (MS) is a chronic disease whose pathogenesis is based on autoimmune neuroinflammatory and neurodegenerative components. The goal of therapy of MS is to reduce the risk of exacerbations and progression of the disease. In recent years, treatment options have expanded significantly with the advent of a greater number of highly effective drugs that alter the course of MS (disease-modyfyung therapies, DMTs) and in the context of the development of a new direction – immune reconstitution therapy (IRT). IRT has a number of advantages, including short treatment courses with long-term effects on immune mechanisms. Cladribine tablets are a selective, highly effective oral form of IRT for MS patients with exacerbations that targets lymphocytes while preserving innate immune cells. Given the increasing number of patients receiving cladribine therapy, questions are increasingly being raised about further tactics for managing these patients, particularly in cases of persistent disease activity despite ongoing pathogenetic therapy. In this review, we publish the results of the consensus opinion of international experts on the analysis of long-term experience with cladribine.


ABSTRACTIn order to study the effect of acidity and different oxygen concentration on coal spontaneous combustion under carbon dioxide-oxygen conditions, Changcun coal was investigated by the Therm...


SUMMARY Neuroendocrines tumors are considered neoplasm lees frequent of the cells of neuroendocrines systems disseminated or localized. They have clinical presentation and biologically conduct very heterogeneous: Low tease cellular proliferation and capacity of liberty biologically products responsibility of specifically clinically syndrome. These kind of heterogeneity don't permit the application of standard treatment, the biologically therapy and chemotherapy are effective in the control of advance disease. We present a clinical case of a 60 years old male patient, with a disease characterized foe edema in left cervical region, hard, fix and no painful. We program 3 cycles with protocol 5 FU, dacarbazine, epirrubicine and obtain a clinical response of 60 %. The heterogeneous of this entity limit the consensus of treatment.


According to cointegration theory and Granger causality test, this paper analyzes the relationship between China's imports of logs and wood forest product exports empirically.The research shows that there is long-term and stable balance between China's imports of logs and wood forest product exports, and Granger causality exists between wood forest product exports and imports of logs.Accordingly, the paper concludes that it is an important issue for China's timber industry to reduce the consumption of imported logs in the short term, but in the long term the realization of the resource base conversion is the fundamental way for China's timber industry to solve the problem of dependence on the imports of timber.On this basis, the paper puts forward policies and proposals to achieve sustainable development of China's timber industry.


Special thanks to the many managers, scientists, and engineers who gave their time to share their perspectives on this process and to the students who spent many hours collecting data and readings: ABSTRACT Recently, there has been a growing interest in the development of collaborative relationships between organizations. Much attention has been given to how firms 'expand the pie' of benefits between them; however, there is little that addresses the ensuing issue-how firms divide the expanded pie. This research examines the pie-sharing phenomenon in collaborations marked by uncertainty in inputs and outputs, information asymmetries, intangible aspects, and noncomparable factors and processes. A conceptual framework is developed that examines the input, task, and organizational characteristics that facilitate the use of equity and equality sharing rules and their consequential effects on relationship outcomes. Survey results of 300 R&D managers, scientists, and engineers provide three surprising results. The first is that a simplified model of sharing is at work in these complex environments. The second insight is that it is not the case that simple rules are used as a simplifying heuristic for complex situations. Third, the judicious application of sharing rules under appropriate conditions has a significant, incremental impact on key relational outcomes. The results underscore the strategic nature of the sharing phenomenon as well as the importance of relational concerns in complex and uncertain settings.


it is very important to in the prevention, design, and maintenance of important facilities for fire protection. Fires occurring in important facilities such as industrial plants must be detected quickly, and the fire must be suppressed to minimize damage. For this purpose, it is necessary to accurately detect the fire and sound the fire alarm. To do this, it is very important to minimize the false alarm and improve the sensitivity of the fire detector. If devices are densely placed in a confined room, cables or switches with electrical contact are particularly vulnerable to fire. In this study, we evaluated a fire alarm and extinguishing system by considering the temperature profile during a cable fire in such a confined space. The fire detection algorithm and integrated management system developed in this study can be applied stably to the flame spreading fire because it can detect the fire faster than conventional detection systems. As compared with conventional smoke detectors, the delay time could be reduced by 20–30% for a fast-growing fire and by 30–60% for a smoldering fire.


This study tempts to investigate the relationship between fluid injection and stress changes in a reservoir at the Longyearbyen CO2-Lab, Svalbard using microseismicity. It is a first step to verify the CO2 injectivity and storage abilities of the reservoir and turn Svalbard into a CO2 neutral community in the near future. We first use the continuous seismic data recorded at eight geophones near the injection well to automatically detect, phase-pick, and locate local earthquakes. Due to the complicated characteristics of the raw data, careful post-processing methods have to be followed to verify the automatically detected earthquakes from the first step. Then we will use those verified microearthquakes to study the migration pattern of the injected fluid and associated stress changes during and immediately after the injection period. In addition, we use a well-identified event, which occurred 17 hours after the water injection test, as a template and search similar events with low SNR using the matched filter method. We have found seven events with six of them occurred on the same day as the template. We will perform a comprehensive search of microearthquakes once we locate more template events.


In accordance with the idea of generalized phase rule, we have studied the necessary condition of existence of predominance area of phase diagram, in which the number of required message input has been reduced to minimum, and set up the computer program for automatically drawing and calculation. In this program system, it contains the following 7 functions: (1) automatically balance the stoichiometric constants of all possible reactions, (2) carry out the Gibb,s free energy calculation of all possible reactions, (3) automatically cancel out the non-existence phase in the designated condition, (4) calculate out all of the locations of 3 phase intersections, 2phase cross lines, (5) find out the phase name, (6) find out the temperature profiles to be interested in, and (7) select the appropriate parameters. This program system has been used in the field of pyrometaUugy for explaining how to select the best operating condition.