We show that the topological Majorana modes in nanowires much longer than the superconducting coherence length are adiabatically connected with discrete zero-energy states generically occurring in short nanowires. We demonstrate that these zero-energy crossings can be tuned by an external magnetic field and are protected by the particle-hole symmetry. We study the evolution of the low-energy spectrum and the splitting oscillations as a function of magnetic field, wire length, and chemical potential, manifestly establishing that the low-energy physics of short wires is related to that occurring in long wires. This physics, which represents a hallmark of spinless p-wave superconductivity, can be observed in tunneling conductance measurements.


The conflict between Palestinian Arabs and Jews is a modern phenomenon, which began around the turn of the 20th century. Although these two groups have different religions (Palestinians include Muslims, Christians and Druze), religious differences are not the cause of the conflict. It is essentially a struggle over land. Until 1948, the area that both groups claimed was known internationally as Palestine. But following the war of 1948-49, this land was divided into three parts: the state of Israel, the West Bank (of the Jordan River) and the Gaza Strip. This is a small area: approximately 10,000 square miles, or about the size of the state of Maryland. The competing claims are not reconcilable if one group exercises exclusive political control over the total territory. Jewish claims to this land are based on the biblical promise to Abraham and his descendants, on the fact that this was the historical site of the Jewish kingdom of Israel (which was destroyed by the Roman Empire), and on Jews' need for a haven from European anti-Semitism. Palestinian Arabs' claims to the land are based on continuous residence in the country for hundreds of years and the fact that they represented the demographic majority. They reject the notion that a biblical-era kingdom constitutes the basis for a valid modern claim. If Arabs engage the biblical argument at all, they maintain that since Abraham's son Ishmael is the forefather of the Arabs, then God's promise of the land to the children of Abraham includes Arabs as well. They do not believe that they should forfeit their land to compensate Jews for Europe's crimes against them. The Land and the People


The mathematic model of voltage-source four-quadrant converter was built based on switching function,and with the transient current control method,the simulating model of converter and control system was established.Steady-state and dynamic simulation in MATLAB was carried out,validating the effect of control scheme.


Contributor considers that the contemporary educational space of Institute of Higher Education is aimed at the development of the personality of students as the carriers of innovation culture, and instructors are called to contribute to this. At the basis of the model developed by the author the idea of the disclosure of the pedagogical potential of the integration of training disciplines and technologies in Institute of Higher Education and the uses of interactive educational technologies lies. The updating of the properties of the personality of student as the carrier of innovation culture – this humanistically oriented pedagogical activity and communication, directed toward the personal development of participants in the educational process (students and instructors), result of which is the disclosure of the creative potential of personality, training competitive specialists with the high level of innovation culture. The pedagogical design of model is oriented to the formation of special innovation space in Institute of Higher Education, when new idea (innovation) is received as value, starts and is supported by the subjects of educational process.


Abstract Several species of anaerobic bacteria display variable Gram stain reactions which often make identification difficult. We have evaluated the Gram stain, the potassium hydroxide test (3% KOH), an antibiotic susceptibility test (10 mg/L vancomycin), and the L-alanine aminopeptidase test (utilising fluorogenic L-alanine-4-methoxy-β-naphthylamide [LAMNA] and chromogenic L-alanine-4-nitroanilide [LANA] substrates) for the preliminary grouping of Gram-positive and Gram-negative anaerobes. By testing 88 clinical isolates, 35 Gram-positive and 53 Gram-negative, we obtained the following results: sensitivity, 49, 94, 21 and 23%; specificity, 100, 98, 91 and 91%; positive predictive value, 100, 97, 79 and 80%; negative predictive value, 56, 96, 43 and 44%, for the KOH test, the vancomycin susceptibility test, L-alanine-4-methoxy-β-naphthylamide test and L-alanine-4-nitroanilide test, respectively. The KOH test correctly grouped all the Gram-positive strains but incorrectly grouped 27 of 53 Gram-negative strains (e.g.Prevotella spp., Fusobacterium spp., Veillonella spp.andLeptotrichia spp.). The vancomycin test correctly identified 33 of 35 Gram-positive strains (resistance withClostridium innocuumandActinomyces odontolyticus) and 52 of 53 Gram-negative strains (susceptible withPrevotella melaninogenica). Both LAMNA and LANA tests correctly grouped 32 of 35 Gram-positive strains but the LAMNA test incorrectly grouped 42 of 53 Gram-negative strains whilst the LANA test incorrectly grouped 41. From the methods examined we conclude that the vancomycin susceptibility test is the most useful for the preliminary classification of anaerobes in the clinical laboratory.


The article is devoted to the study of the expansion of esoterism in polystylistic culture. There is attempted to define the term «esoterica». There are shown some of the reasons for the wide popularity of the modern esoterical thought.


An element (10) of a lighting device (1) having: - a cavity (12) defined by a side wall (16) and a bottom wall (18), said cavity (12) housing at least one electrical connection element (14), the cavity (12) having a free supporting edge (20) shaped to receive a gasket (2) disposed substantially perpendicular to said side wall (16), - the ribs ( 22) integral with a face (16a) of the side wall (16) opposite the cavity (12) extending substantially perpendicularly to the side wall (16), each rib (22) defining a bearing edge ( 23) shaped to receive and support said gasket (2) when it is disposed substantially perpendicular to said side wall (16), characterized in that at least one of the ribs (22) is a notched rib (22 '), whose bearing edge (23) has an indentation (24) extending along the side wall (16) from the bo rd free bearing (20) of the cavity (12).


The Edison Company's Big Creek hydroelectric development is served by three storage-reservoirs, namely, Huntington, Florence, and Shaver lakes, having a combined capacity of 288,523 acre-feet. These three reservoirs impound the runoff of Bear Creek, Mono Creek, South Fork San Joaquin River, Big Creek, Pitman Creek, and Stevenson Creek. The combined area of the six drainage-basins is 450 square miles, 45 per cent of which is above an elevation of 10,000 feet.

Using the direct method of forecasting, we predicted a runoff of 836,000 acre-feet on March 1, 1941, and a runoff of 745,000 acre-feet on April 1, 1941. The actual runoff received between November 1 and July 31 was 810,000 acre-feet, indicating an error of +3.2 per cent as of March 1 and an error of −8.0 per cent as of April 1 for our forecasts for 1941.


This study evaluated the microbial viability of fish gut microbiota in both digesta (faecal) and mucosal samples using a modified propidium monoazide (PMA) protocol, followed by 16S ribosomal RNA (rRNA) gene sequencing.


Urinary tract infection (UTI) is the most common community-acquired bacterial infection affecting people of all age groups and both sexes. Aims: This study was performed to isolate bacterial pathogens usually cause community-acquired uncomplicated UTI and to evaluate their sensitivity against 9 different antibiotics. and of Study: This study was conducted Department Microbiology, Jessore hundred fifty urine from Pathogenic were isolated and identified using conventional and biochemical methods. Kirby-Bauer disc diffusion method on Mueller Hinton agar media was used for the determination of sensitivity of the positive isolates to commonly prescribed antibiotics. Statistical Package for Social Sciences (SPSS) software, version 20 was used for statistical analysis. was the most predominant bacteria in both gender and different age groups. Cefixime (94.52%), Cephalexin (94.52%) and Azithromycin (93.15%) were the most effective drugs and Nalidixic acid (13.69%) was the least effective drug for the treatment of UTI.


In order to update the IUCN Red List of all freshwater fish species inhabiting the Maghreb region, comprehensive knowledge of their respective geographic ranges is essential. Here we present site-scale distribution records derived from all known sources for native and alien freshwater fish species distributed in Morocco, Algeria and Tunisia. Corrected data compiled from the Global Biodiversity Information Facility plus author contributions and digitised literature data are presented as GIS maps, and the wider scientific and conservation communities are called upon to help fill knowledge gaps and maximise the value of this new database for a region in which freshwater biodiversity is undergoing a serious decline.


Anisotropic networks, elastomers and gels exhibit piezoelectric, pyroelectric, ferroelectric and NLO properties of potential interest for use communication and processing technologies. The formation, properties and applications of such anisotropic, mainly liquid crystalline, networks are described. If some of the molecules in a liquid mixture contain at least two reactive groups which can be either photochemically or thermally polymerized, then crosslinked, anisotropic networks, elastomers and gels can be produced. Solid macroscopically aligned elastomers or networks can be formed as required beforehand or simultaneously by orientation of the sample. Anisotropic gels consist of a solid anisotropic network and non-covalently bonded, but strongly oriented domains of low molar mass liquid crystals. Anisotropic networks, elastomers preformed amorphous or liquid crystalline polymers incorporating additional reactive groups, which can be macroscopically oriented in the additional crosslinking reactions. Reversi...


The perioperative management and clinical course of per‐oral endoscopic myotomy for patients receiving antithrombotic therapy remains unknown. This study aimed to clarify the status of antithrombotic therapy in per‐oral endoscopic myotomy and to determine its safety and efficacy.


Photon transport is considered in an interstellar cloud containing
one or several photon sources (stars), defined by
$q_i\delta( x- x_{\i})\,i=1,2,\ldots,$ where the
locations $x_i$'s are given in a stochastic way. First, the case
is examined of a single source of intensity $q_1$ and located at
$x_1$ with a probability density $p_1 = \p(x_1)$, such that
$\p(x_1)\geq 0$ and $\int_V \p(x_1)\dx_1 = 1$, where $V
\subset \R^3$ is the region occupied by the cloud. Then, a
Boltzmann-like equation for the average photon distribution function
 $(x,u;x_1)$ is derived and it is shown that
$\p(x_1)$ can be evaluated starting from a far-field measurement
of . Finally, the case of two or more photon sources is
discussed: the corresponding results are reasonably simple if
$\p(x_1,x_2) = \p_1(x_1)\p_2(x_2)$, i.e. if the
locations of the two photon source are "independent".


This Final Report presents the results of work accomplished in accordance with the Scope of Work to the Purchase Order No 4596310. The amount of works includes the following items: 1. Start of the manufacture of the Experimental Accelerating Stand (EAS)-the section for proton acceleration from 5 MeV to 8 MeV, in which RF fields are excited by an electron beam at the anomalous Doppler effect. 2. Theoretical investigation and computer simulation of field excitation and ion acceleration in the EAS. Under item 1, the EAS manufacturing is begun. To present time, a pedestal for the EAS and a stainless steel vacuum chamber for RF resonator are made (length of the chamber is about 180 cm, diameter is about 40 cm). Besides, parts of the EAS resonator with the acceleration structure are manufactured, and its assembly is begun. Under item 2, it is realized three works: calculation of increment and frequency shift of the EAS resonator excited by electron beam, calculation of the solenoid for creation of magnetic field with required spatial distribution, and theoretical investigation and computer simulation of ion acceleration in the EAS. 14 figs., 16 refs.


Gilben Stelter has remarked that ' 'housing remains a neglected subject ... '' in Canadian historical research. 1 Nothing highlights the truth of that assenion more clearly than the issue of whether homeownership rates increased or decreased in Toronto in the first two decades of this century. The conventional wisdom is that they declined slightly. This has rested on impression rather than evidence ,for Census data on homeownership have been available only since 1921. The implication of recent evidence published in this journal by Gordon Darroch, however, is that the early years of the century saw an unprecedented homeownership boom. 2 Darroch himself makes no reference to this ,for his concern was with the decades prior to 1899. The purpose of this note is to review the evidence, direct and circumstantial, concerning ownership trends in Toronto between 1899 and 1921, and to suggest how a homeownership boom might have occurred at a time when real incomes increased little, if at all.


minorities, residential housing segregation, income inequality, uninsured persons, diabetics, or mobility outside the home during the pandemic. Conclusions. To our knowledge, this study provides results from the most comprehensive multivariable analysis of county-level predictors of rates of COVID-19 cases and deaths conducted to date. Our findings make clear that ensuring that COVID-19 preventive measures, including vaccines when available, reach vulnerable and minority communities and are distributed in a manner that meaningfully disrupts transmission (in addition to protecting those at highest risk of severe disease) will likely be critical to stem the pandemic.


The ability of fragments of incisor enamel organ and lip-furrow epithelium from 15- and 16-day old embryonic mice to regulate into harmonious tooth constructions is described. The cervical loop and upper half portions of the incisor enamel organ were confronted with incisor or molar dental papillae. Similar combinations were made from lip-furrow epithelium and incisor or molar papillae. The cultures were grown in the anterior chambers of homologous host eyes. The epithelial fragments from the incisor enamel organ when associated with the dental papillae reconstruct teeth typical in all respects; enamel and dentin matrices are deposited. Lip-furrow epithelium arises from the oral epithelium and is temporally and spatially related to the incisor dental epithelium proper. This ectopic epithelium was confronted by incisor and molar papillae. Harmonious teeth developed in these explants. It is concluded that the ability of the dental papillae to elicit new cytodifferentiative and biochemical syntheses from the lip-furrow epithelium indicates that the dental papillae act inductively during tooth ontogeny. The shape of the teeth reconstructed from enamel organ fragments and lip-furrow epithelium were incisiform or molariform in response to the incisor or molar dental papillae. These data confirm the conclusion that the structural specificity for tooth shape resides in the dental papilla.


As part of the IEEE Signal Processing Society (SPS), the Speech and Language Technical Committee (SLTC) promotes research and development activities for technologies that are used to process speech and natural language. Much of the SLTC's efforts are devoted to the annual IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP), where the SLTC manages the review of papers covering speech and language and organizes conference sessions, special sessions, and tutorials. In addition, it promotes and supports various workshops, most prominently the Automatic Speech Recognition and Understanding (ASRU) and the Spoken Language Technology (SLT) workshops.


We are considering the possibility of placing the space of any length in the "point" (ie, in a small region of space), including the Universe at the "point" with to the Planck size. The problem is solved in a multidimensional space.


Main conceptions of the economic risks in the modern Russian economy application are given in the article. The author classifies the economic risks according to the level of institutionalization in modern society.


Humans modulate the behavior flexibly after timely receiving and processing information from the environment. To better understand and measure human behavior in the driving process, we integrate humans and the environment as a system. The eye-movement methodologies are used to provide a bridge between humans and environment. Thus, we conduct a goal-directed task in virtual driving to investigate the law of eye-movement that could characterize the humans (internal) and environmental (external) state measured by fixation distribution and optical flows distribution. The analysis of eye-movement data combined with the information-theoretic tool, transfer entropy, active information storage, quantify the humans' cognitive effort and receiving information, and in fact, there is a balance (optimal) range between two, because of the mutual synergy and inhibition, whose quantified value is named balance of information processing. Subsequently, we update a system-level model, finding that those information measurements, transfer entropy, active information storage, and balance of information processing, all are included. This information set is information flow, which is quantified by the square root of Jensen-Shannon divergence (SRJSD), named information flow gain. What's more, results also demonstrate that the influence of system-level information flow correlated with behavioral performance stronger than the separate measurements. In conclusion, we research humans' eye-movement based on information theory to analyze behavioral performance. Besides driving, these measurements may be a predictor for other behaviors such as walking, running, etc. Still, the limitation is that the information flow may be a proxy of determinants of behavior.


Cheese is a well known and popular dairy food produced around the world, and cheese processing involves several steps, including the addition of rennet, lactic acid and/or lactic acid cultures, coagulation, cutting the curd, syneresis, and storage (Brighenti et al., 2018). Cheese consumption in Brazil corresponds to 5.9 kg/hab/year, with a growth of 68.8% in the last 6 years (Gomes et al., 2017). Despite the changes in eating habits and consumption trends of the population, Mozzarella, Prato cheese, Requeijão, and Minas cheese are the varieties most preferred by the Brazilian consumers, thus most produced in the country (Gomes et al., 2017). On this context, regardless of the type of cheese, a large amount of effluent has been generated by the cheese industry (Carvalho et al., 2013).


FIELD: machine building. SUBSTANCE: plant includes a controller operating under the control of a computer, a layer-by-layer extrusion settlement system containing a construction chamber, a base assembly, a gantry, a holder retained with the gantry; at that, gantry is intended to move the holder relative to the base assembly, a loading compartment; a replaceable cartridge. The replaceable cartridge includes a container assembly provided with possibility of storing a thread source and loaded at least to one loading compartment of the layer-by-layer extrusion settlement system, a guide tube connected to the conveyor assembly and a pumping assembly connected to the guide tube and having the possibility of introducing to the holder of the layer-by-layer extrusion settlement system and removing from the holder. EFFECT: increasing the construction efficiency and reducing distortions in three-dimensional objects. 20 cl, 13 dwg


Among the hydrogels prepared in recent years, double network (DN) hydrogels exhibit the highest compression strength, toughness, and fracture energies. However, synthesis of DN hydrogels with extraordinary mechanical properties is limited to polyelectrolyte networks, which hinders their widespread applications. Herein, we prepared nonionic DN and triple network (TN) hydrogels based on polyacrylamide (PAAm) and poly(N,N-dimethylacrylamide) (PDMA) with a high mechanical strength by sequential polymerization reactions. The TN approach is based on the decrease of the translational entropy of the second monomer upon its polymerization in the first network, so that additional solvent (third monomer) can enter into DN hydrogel to assume its new thermodynamic equilibrium. The first network of TN hydrogels comprises chemically cross-linked PAAm or PDMA while the second and third networks are linear polymers. To increase the degree of inhomogeneity of the first network hydrogel, an oligomeric ethylene glycol dimeth...


1. Heikki Ikaheimo & Arto Laitinen Recognition and Social Ontology Recognition and the Social Ontology of Personhood 2. Robert B. Brandom The Structure of Desire and Recognition: Self-Consciousness and Self-Constitution 3. Robert B. Pippin On Hegel's Claim that Self-Consciousness is "Desire Itself" ("Begierde uberhaupt") Pirmin Stekeler-Weithofer Intuition, Understanding, and the Human Form of Life Hegel, Marx, and Beyond: Recognition, Spirit and Species Being 5. Ludwig Siep Mutual Recognition: Hegel and Beyond 6. Heikki Ikaheimo Holism and Normative Essentialism in Hegel's Social Ontology 7. Paul Redding The Relevance of Hegel's "Absolute Spirit" to Social Normativity 8. Michael Quante Recognition as the Social Grammar of Species Being in Marx Groups, Institutions and Recognition 9. Margaret Gilbert Mutual Recognition and Some Related Phenomena 10. Italo Testa Social Space and the Ontology of Recognition 11. Arto Laitinen Recognition, Acknowledgement, and Acceptance 12. Titus Stahl Institutional Power, Collective Acceptance, and Recognition 13. Vincent Descombes The Problem of Collective Identity: The Instituting We and the Instituted We Notes


The tourism sector has been predicted to be the second largest source of foreign exchange contribution in Indonesia, but the Covid 19 pandemic has made this sector sluggish. The Government of the Republic of Indonesia has made various efforts so that this sector can return to normal. Starting from restricting people traveling, using masks when going out and always washing hands. At the time of tourism in the Covid 19 era, it is believed that millennial generation tourists will continue to carry out their activities. The millennial generation is relatively bolder when traveling on tour when compared to previous generations. With the opening of tourism in the Covid 19 era, the millennial generation will immediately carry out tourism travel activities. Perception is the process of an individual selecting, organizing, and interpreting information inputs to create a meaningful picture of the world. Millennial generation tourists' perceptions focus on risks when traveling. Contracting the covid 19 virus is the biggest risk. Attitude is an evacuation of trust for positive feelings or negative feelings from someone if they have to do behavior that will determine. Attitude is a characteristic that is owned by a person in forming a character, this character is a principle that is owned and is static or difficult to change. The number of respondents in this study were 100 tourists. The results of this study are the perceptions of millennial tourists towards tourism in the new normal era prioritizing the quality of health protocols both in hotels, restaurants, transportation, and in tourist objects. Similarly, the attitude of millennial tourists towards tourism in the new normal era is more concerned about health and hygiene when traveling.


Using ultrashort pulsed optical excitation and interferometric detection, we dynamically image ultrahigh-frequency surface acoustic phonon wavepackets on two-dimensional (2D) phononic crystals. The samples consist of a square lattice of air-filled holes etched in a silicon substrate. Good agreement is found when compared with time-domain finite element numerical simulations. By Fourier transformation, the dispersion relation is derived and stop bands are revealed. The spatial distributions of the acoustic eigenmodes at specific frequencies are also presented.


A 45-year-old man with no medical history presented with behavioral changes. He was withdrawn from his family and friends. Home and finances had fallen into disorder. He was disheveled and incontinent of urine and feces. He lacked insight into his cognitive decline. His skin was bronzed and the examination was notable only for upgoing plantar responses. Peroxisomal fatty acid profile was elevated at C24:0 at 138.9 nmol/mL (normal <91/4), elevated C26:0 at 5.05 (normal <1.39), and elevated C26:0/C22:0 ratio at 0.062 (normal <0.023). Images show abnormal high signal on fluid-attenuated inversion recovery (figure 1) with enhancement (figure 2).


Report on Surface contamination: its genesis, detection and control, International Committee of Contamination Control Societies, and the Institute of Environmental Sciences (USA), 10-13 September 1978 at the Capitol Hilton Hotel, Washington DC, USA.


Smart buildings improve energy efficiency and provide ancillary services to the power grid. Such services are based on model-based mechanisms that require availability of accurate models of the different building loads such as heating, ventilation, and air conditioning (HVAC) systems. Although numerous efforts have been made in the area of constructing a thermal model for a building HVAC system, almost all models have shortcomings. In this paper, we employ the nuclear-norm-based subspace method to identify a locally accurate HVAC system model. We consider the more general case of a multi-zone building HVAC system, i.e., each zone has its own thermostat and can be set to a different temperature. The estimated HVAC system model can be used to predict the future indoor temperatures. This will assist power utility companies and building managers in estimating the upcoming load shape, especially the peak amount and duration.


It has been increasingly accepted that a 'paradigm shift' to sustainability in the built environment is not only necessary but also inevitable. Nevertheless, this will not occur unless there is a fundamental change in personal values, as these will play a significant role in behavioural change towards sustainability. However, most current sustainable building practices and indictors are still based on a framework of values appropriate for an industrial-affluent-consumer society. It is therefore certain that a better understanding of notions of value, the differences between dominant values of the present society and sustainable values, whether architecture reflects sustainable values, and strategies for producing value change in the built environment are all necessary to promote physical change in the built environment. This paper first clarifies notions of values, provides a framework of sustainable values, and compares difference approaches to value change in the built environment by examining two case studies, the Hockerton Housing Project (HHP) by the Vales in the UK and the New Cave Dwellings (NCD) (Yaodong) by the Green Building Research Center of the Xi'an University of Architecture and Technology in North Central China. Although the two projects both reflect similar sustainable values, the approaches to value change are quite distinctive. The HHP shows how to implement sustainable values in the built environment from a Western perspective, while the NCD presents an example of how the traditional culture and forms of Chinese cave dwellings are preserved and adapted to produce a 'modern' sustainable built environment, thus offering a linkage between vernacular architecture and sustainable architecture. Through exploration of the two case studies, this paper concludes that undertaking sustainable building predicated on maintaining the status quo of values may make it impossible to bring forth a 'paradigm shift' in architecture, and that despite similar goals of placing sustainable values into the built environment, strategies and implementations should be diverse with regard to different cultures.


Private management has become an important alternative for the provision of public services in Brazil - a result of a widespread belief that associates the non-governmental sector with higher levels of efficiency. The aim of this paper was precisely to measure the impact of private management in SUS, through the estimation of a regression model for counting data. The database used consisted of a panel of data, organized on the basis of information from the Brazilian Institute of Geography and Statistics and the Information Systems Department of the Ministry of Health, Datasus, covering all Brazilian municipalities between 2000 and 2003. Results did not confirm that private management of public funding leads to a reduction in the number of deaths. In fact, results are unexpectedly significant and negative, which suggests that the improvement in the Brazilian public health sector, i.e. the reduction in child mortality rates, was not caused by its hybrid public-private institutional design.


We investigate using signal detection techniques for testing the audio capability of television sets in an industrial production line with the objective of identifying defectives devices. Two approaches were investigated in this study: the first was based in searching for specific frequencies of sufficiently high magnitude, and the second on detecting specific patterns of alternating frequencies. The results suggest that the first approach is highly susceptible to noise, while the second overcomes this problem, detecting all patterns in the audio segments.


Index system of land eco-environmental status evaluation was constructed from Landsat TM image of 1996 and 2005 based on RS.Supported by GIS special analysis function and geological statistical function,the mini-watersheds was used as evaluation unit based on the land use and its changes,the land eco-environmental status index(EI) model was used to evaluated and the changes results of EI was studied.The result shown that: this region was major agriculture and forestry,land-forestland was at high frequency,the forestland,water area and construction land have high retention rates,and the grassland,unused land and cultivated land have high conversion rates,the total of he land eco-environmental status in 2005 was general,the tendency was better compared with 1996,the proportion of slightly and basic better region was 21.39%,the proportion of unchanged region was 78.17%,which occupied dominant position,the proportion of slightly worse region was lowest,this result had noticeable significance to the regional land eco-environment protection and its improvement.


The emission fluxes and the distribution of dissolved methane (CH4) and carbon dioxide (CO2) were determined for 11 sampling stations in two hydroelectric reservoirs (flooded since 1978 and 1993) located in the James Bay territory of northern Quebec. The measured benthic fluxes for the two greenhouse gases were found to be either higher or similar to those determined at the water-air interface during the ice-free sampling periods. For the 2 year duration of the study, emission fluxes of CH4 to the atmosphere generally varied between 5 and 10 mg m−2 d−1, while those for CO2 ranged from 500 to 1100 mg m−2 d−1. Furthermore, through the use of static chambers at the water-air interface, we determined that the emission fluxes for the gases are controlled by molecular diffusion. Our calculated fluxes have been separated into two groups: (1) regular emission fluxes and (2) above-average emission fluxes. The first type comprises the majority of fluxes measured during the sampling periods (i.e., 88% for CH4 and 87% for CO2). The second group reflects unusual sampling conditions (e.g., strong winds, water column depths of less than 1 m, or flooded peatland mats floating at the surface). Although data for this group are limited, our preliminary results suggest that they may be an important component in an atmospheric emissions budget for large reservoirs. Concentration profiles for CH4 and CO2 dissolved in the water column clearly show that oxidation and/or horizontal advection of these gases are controlling factors in their subsequent release to the atmosphere. Most of the CH4 is oxidized within the first 25 cm above the flooded soil-water interface. Consequently, neither benthic emissions of CH4 and CO2 nor the type of flooded soil appear to control atmospheric emissions of these gases from hydroelectric reservoirs.


Müller, Roland E. Schmieder, Alexander Cavallaro, Kai-Uwe Eckardt, Michael Uder, Friedrich Christoph Kopp, Peter Linz, Anke Dahlmann, Matthias Hammon, Jonathan Jantsch, Dominik N. Hypertensive Patients Na Magnetic Resonance Imaging-Determined Tissue Sodium in Healthy Subjects and 23 Print ISSN: 0194-911X. Online ISSN: 1524-4563 Copyright © 2013 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Hypertension doi: 10.1161/HYPERTENSIONAHA.111.00566 2013;61:635-640; originally published online January 21, 2013; Hypertension. http://hyper.ahajournals.org/content/61/3/635 World Wide Web at: The online version of this article, along with updated information and services, is located on the http://hyper.ahajournals.org/content/suppl/2013/01/21/HYPERTENSIONAHA.111.00566.DC1.html Data Supplement (unedited) at:


(Medical Xpress)—In the familiar rendering of a neuron, as in the image above, the so-called electrical spikes are usually depicted as short pulses. In reality, if the spike lasts for over a millisecond and its expanding front travels at 100 meter/second, then we are in fact talking about a physical disturbance that would extend some 10cm. Insofar as artists are informed by real neuroscience, and not fantasy, it also becomes necessary to insure that neuroscience is informed by real physics. In a recent discussion of brain activity maps, we made ample mention of the fact that this electrical disturbance is a multiphysical event whose full experimental signature is only partially accounted for by current models. A mounting body evidence now suggests an alternative, and more fundamental explanation—neurons and their membranes in particular, send signals to each other using sound.


Plant growth promoting (PGP) potential of rhizospheric and endophytic bacterial isolates of capsicum (Capsicum annuum L) obtained from different agro-climatic zones of Himachal Pradesh was studied. Total of 10 isolates (RS1-RS10) were morphologically and physiologically characterized and tested for multifarious PGP traits viz phosphate solubilization, auxin and siderophore production. Nutrient broths having 1.5 OD at 540 nm were used as inoculum and 4 hours as seed imbibition time period. Only six isolates (RS2, RS3, RS4, RS7, RS8, RS10) possessing maximum of PGP traits were evaluated for seed germination and seedling growth studies under controlled conditions. Isolates were tried singly as seed inoculation in Completely Randomized Block Design replicated thrice. All the selected isolates were Gram positive rod, differed in colony morphology, showed optimum growth at 35°C and 7 pH and possessed various PGP traits. Maximum seed germination (84.4%), increase in shoot length (41.54%), shoot biomass (41.46%), root length (69.64%), root biomass (42.85%) over uninoculated control were noted for RS7 isolate inoculated seeds. The RS2 isolate inoculation in general had the similar effect of studied plant parameter. Present investigations focus on potential use of isolate RS7 (Bacillus spp) and RS2 (B subtilis) as biofertilizer for capsicum under north-western Himalayan region.


Through an analysis of the deficiency of the traditional mining right management,this paper advocates the establishment of mining right management system based on professional GIS modules.The paper determines the main function and designs the systematic overall frame of the system,discusses the operation mode,data management mode and other problems,and then puts the system to use.Applied in the establishment of the Land Resource System of Maoming City,the mining right management system has found a wide use.


The idea of the ensemble – as encompassing areas within plans of composite medieval towns that can be recognized as being co-functional and contemporary in origin – is argued as being an important concept in enabling the course of urban development to be unravelled in a meaningful way. In a number of cases the use of this concept, as applied to the course of development of early medieval towns, can counteract the tendency for the interpretation of spatial distinctions between different 'morphological areas' within a town plan to be regarded as evidence of sequential development. This is exemplified in the discussion of a number of examples of town plans in which the application of this concept can generate new historical narratives concerning their early development.


Following the Norman Conquest in 1066, a variety of French known as Anglo Norman was introduced into the linguistic landscape of Medieval England. While previous studies have examined the influence of French lexicon on English, less attention has been given to the influence of French on English grammatical structures in this language contact scenario (Ringe & Eska, 2012). As scholars have noted cross-linguistically, possession represents a domain of grammar that is affected by language contact (Aikhenvald, 2012; McConvell, 2005). Covering the period of late Middle English, from 1300 to 1500, this project examines the influence of Anglo Norman on Middle English possessive constructions.The sources for this study are published Trade Guild Records of London companies, taking points of comparison with texts from regional dialects. Guild merchants represent an influential class of 'middle men' in London, whose records have hitherto been marginalised in linguistic analysis (Miller, 2012). As the London dialect formed the foundation for the standardisation of English (Wright, 2005), the multilingual practices of this group represent a perspective on everyday language use of this influential variety.Through the analysis of language practices in multilingual texts, this study fills a gap in the academic literature on the Middle English expression of possession by considering language contact as an explanation for developments during this period. Myers-Scotton's (2002) Matrix Language Framework provides the methodological frame for the analysis of the multilingual Trade Guild Records. Specifically, the project examines four outcomes of language contact attested in the data: code-switching in inflectional morphology, the replacement of zero-marking with overt morphemes, grammatical replication, and double-marking. These outcomes are related to the possessive forms of the English s genitive, the English and French zero genitives, the English of and French de prepositional constructions, and the 'double-marked' or oblique genitive in English (i.e. X of X's). The findings for this study demonstrate that Anglo Norman has influenced Middle English possessive constructions in measurable ways.


Based on management practice of industry land in Shanghai,this paper proposes a mechanism to execute full-process evaluation of industry land.The mechanism covers foreward-among-afterward phases of industry land examining and approving,which emphasizes land intensivism to be used in project design and engineering feasibility prejudication,land scale and intensity to be evaluated among examining and approving,and land integer performance to be evaluated afterward.The preliminary application of this mechanism is analyzed finally.


In this paper, we propose a method to detect spam tweets containing unhealthy information by using an n-gram dictionary under limited labeling. Spam tweets that contain unhealthy information have a tendency to use similar words and sentences. Based on this characteristic, we show that spam tweets can be effectively detected by applying a Naive Bayesian classifier using n-gram dictionaries which are constructed from spam tweets and normal tweets. On the other hand, constructing an initial training set requires very high cost because a large amount of data flows in real time in a twitter. Therefore, there is a need for a spam detection method that can be applied in an environment where the initial training set is very small or non exist. To solve the problem, we propose a method to generate pseudo-labels by utilizing twitter's retweet function and use them for the configuration of the initial training set and the n-gram dictionary update. The results from various experiments using 1.3 million korean tweets collected from December 1, 2016 to December 7, 2016 prove that the proposed method has superior performance than the compared spam detection methods.


The charge transfer reaction between cefotaxime sodium and p-benzoquinone was studied by spectrophotometry.The optimal experimental conditions for the formation of charge transfer complex were confirmed.At room temperature,cefotaxime sodium reacted as electron donor with electron receiver p-benzoquinone in borax medium and to form a charge transfer complex with ratio of 1:2,and the apparent molar absorptivity coefficient was 9.92×103L.mol-1.cm-1 with the biggest absorption wavelengh at 587.5nm,and the range linearity of cefotaxime sodium obeyed Beer's law in the range of 2—36μg/mL.The machaism of formation of charge transfer complex was investigated.The method was applied for the determination of cefotaxime sodium of injection.The recoveries were 98.43%—100.4% and the relative standard deviation was less than or equal to 2.65%.


We constructed a functional DNA molecule model on the basis of a flexible helicoidal sensor, specifically, a pretwisted hollow nano‐strip. We study in this note the helicoidal nano‐sensor model with a pretwisted strip axial extension corresponding to the overstretching transition of DNA from dsDNA to ssDNA. Our model and the DNA molecule have similar geometrical and nonlinear mechanical features unlike models based on an elastic rod, accordion bellows, or a combination of "multiple soft and hard linear springs", presented in some recent publications.


The mode of reproduction of Carboniferous cockroaches (in protective chitinous cases) permitted post-Permian survival of the order. It serves as a basis for subdivision into the Eoblattodea and Neoblattodea. Details of the survival and evolution are discussed.


The article probes the history from technology's reasoning into its system,analyzing its tendency as the implementation.And it also criticizes Marlkusurt,whose theory was on behalf of the technology's reasoning.


The usage of natural products and fungicides are the most promising methods which available to control fungal growth and toxins production in food. Our data indicated that the peanut samples that infected with 3.85 x 10 6 /ml Spore suspension have a quickly development after 4 days which increased in the positive control from 1, 2, 0 and 0 for B1, B2, G1 and G2 to 199, 148, 175 and 170 ng/g respectively. The levels of aflatoxins were developed to reach 219, 158, 205 and 185 ng\g after 8 days, respectively. Maximum levels were 224, 188, 235 and 160 ng/g after 12 days. It can also be noticed that a good minimization in toxin production was occurred by the direct usage of 5, 10 ppm Neem leaf extract. The data showed a gradual reduction of Tolcolofos-methyl (Rizolex) residue in the treated samples from 450 ppb at initial time to 10 ppb after 30 days. No detectable amount was observed after 45 days. That clearly indicates the outbreak in fungal growth after the first 45 days. That means when the Rizolex residue was completely disappeared after 45 days, fungal growth and aflatoxins B1 and B2 production started again with an abnormal high level because of the death of fungal antagonistic microorganisms. It can be concluded that when a storage period for more than 45 days, Maize needed a second treatment with 3g/kg Rizolex to guarantee a complete prevention of fungal growth and aflatoxins production.


In the paper the results of an experimental program intended to determine factors influencing the impact resistance of the External Thermal Insulation Composite Systems (ETICS) were presented. For the research the systems based on polystyrene have been chosen. The insulation material was faced with a rendering consisting of base coat reinforced with standard or armored glass fibre mesh and silicone or silicone-silicate binders as finishing coats. The influence of various renderings components was evaluated with respect to resistance to hard body impact and resistance to hail. The test results were discussed in the context of the possible impact level on ETICS in use.


Loss of Interest in Studying the French Language Among University Students in Nigeria: The case of Osun State University students
In principle, language is an instrument of communication between communities. As the world has become a global village, we are entering an era where the future of a nation will have to be based on multilingualism, a situation with serious consequences. In view of this multilingual context, it is therefore important to learn a foreign language. Based on Skinner's behaviorist theory, this study examines the reasons or factors responsible for the loss of interest and lack of motivation to learn French among university students. The study maintains that students' interest, motivation and satisfaction must be taken into account in school activities. Using the questionnaire for 50 students which will serve as a tool for a qualitative result, we would identify this alarming challenge among students in the French department of Uniosun. This study concludes that it would therefore be necessary to let learners in foreign language departments decide for themselves whether they want to learn French instead of forcing them to learn the language. France also has an important role in promoting its language (teaching and learning) in Nigeria.


Risk analysis is within the realm of corporate planning. Risk analysis is vitally important for the Petroleum Industry and other natural resource based firms. This paper attempts to develop a theoretical concept that could be coined {open_quotes}corporate political risk.{close_quotes} Stemming from the notions of political risk, country risk, and sovereign risk, the work seeks to portray innovative avenues not only for the characterization of corporate risk but also for indicators that would allow methods to operationalize and measure it. In this analysis, the main features of political risk assessment, its bibliography, and main research methods and techniques will be reviewed. With those elements as background, new theoretical ideas, their conceptualizations and implementation will be advanced in order to identify, quantify, and evaluate corporate political risk (CPR). There are several instances when an investment abroad looks much more attractive than one at home. However, perhaps the most important reason for investing overseas is when the foreign expected rate of return exceeds that offered domestically. Whether for this reason or others, when a corporation begins investing beyond its national boundaries new risks-political in nature-start to emerge. Foreign governmental interference with the operations of the investing firm could be expected, and corporate decisionmore » makers confront the potential for eventual politically inflicted damage to their interests.« less


As renewable energy comes from naturally available and are not much expensive. So among solar, wind, tidal energy, wind energy is considered to be proven technology. Comparing cost of electricity generation, now days Wind Energy Conversion System (WECS) is built for meeting both grids connected and standalone load demand. WECS is the machine consists of wind turbine which has wind energy as a input and it generates mechanical energy as output. This mechanical output is given as input to electrical generator for generating electricity. In this paper, for purpose of continuous supply of power, storage device like battery is used as a backup and to fulfill the requirement of standalone DC load, for which a hybrid of wind and battery system is proposed. The charging and discharging of battery is based on turbine maximum power point (MPPT) technique. The mechanical and electrical protection is provided by pitch control technique. The proposed Wind Energy Conversion System will be simulated in MATLAB/SIMULINK by integrating MPPT charging control technique and pitch control


Objective To develop a transitional care program led by advanced practice nurse(APN) for patients with type 2 diabetes and to evaluate its impact on the patients' treatment compliance and glycemic control.Methods A random sampling method was used.96 patients with type 2 diabetes from an inpatient department were divided into an intervention group and a control group randomly.Both groups received regular nursing service,and the intervention group also received transitional care led by APN.The treatment compliance and glycosylated hemoglobin Alc(HbAlc) of the patients were collected before and 4 and 12 weeks after the intervention.Results 4 weeks after the intervention,the total average score of treatment compliance and the scores of "self-monitoring","exercise",and "diet-control" were statistically higher in the intervention group than in the control group(P < 0.05).12 weeks after intervention,the total average score of treatment compliance and the scores of "self-monitoring","medication",and "diet-control" were statistically higher in the intervention group than in the control group(P < 0.05).The t-test showed that there was no statistical difference in HbAlc between the two groups 12 weeks after the intervention.But more patients were qualified in HbAlc in the intervention group than in the control group (P < 0.05).Conclusions Transitional care program led by APN is an effective approach in improving treatment compliance and making more patients qualified in HbAlc.

Key words:
Advanced practice nurse (APN) ;  Transitional care program;  Treatment compliance; Glycemic control


In this paper, we describe a hybrid recommendation system combining the two main approaches to recommendation collaborative filtering and content-based classification. We build a collaborative filtering framework to construct a useritem matrix of ratings and produce recommendations based on user-user similarity computed using Pearson correlation. We tackle the sparsity of the user-item matrix by incorporating a NaiveBayes classifier for each user and using it to predict the unknown ratings in the user-item matrix. We presents results from applying our approach to a movie recommendation database provided by the Netflix movie rental service.


We examine the hypothesis that Pliocene exhumation of the external massifs in the central Alps is controlled by climatic change. New thermochronological data from the western Gastern‐Aar massif are used to investigate the timing, extent, and reasons for Neogene exhumation. Our data reveal that exhumation was constant with 0.5 km/Ma over the last 10 Ma in the north. In the southern part, exhumation was of the same order until ∼3.5 Ma but then increased gradually toward the south to values of up to 1.2 km/Ma, resulting in overall northward tilting of the western Aar massif. We explain this accelerated exhumation in the south after ∼3.5 Ma mainly by tectonic denudation in the footwall of the Rhône‐Simplon fault and discuss changes in deep crustal configuration, which may have triggered south directed normal faulting. We propose that the Rhône river was structurally trapped by the Rhône‐Simplon normal fault zone, which additionally enhanced erosion in the southern section of the Aar massif. Climatic forcing may have an impact in the very late stage of exhumation due to Alpine glaciation in the late Pliocene.


Gives an implementation method based on home net appliance, which solves the problem of how to realize WEB information released from network appliance in the intranet to the internet by dialing. And introduces some problems during the process of realization, gives a solution based on the Apache server and the Mysql in Linux.


A thermosetting resin composition which comprises, as essential ingredients, (A) a thermoplastic resin having a polyhydroxyether skeleton represented by the general formula (a) and/or polyhydroxyether skeleton represented by the general formula (b) in which 5 to 99 mol% of the hydroxy groups have been esterified and (B) a thermosetting resin. (In the formulae, R1 represents C1- 18 aliphatic- or aromatic-ring-containing alkylene or -SO2-; 5 to 99 mol% of R2 is accounted for by a linear or cyclic C1- 20 carbonyl group or an aromatic carbonyl group and the remainder, i. e., 95 to 1 mol% of R2, is accounted for by hydrogen; and R3 represents hydrogen or methyl, provided that the R3s' may be the same or different.). ® KIPO & WIPO 2007


In this paper, we propose an efficient modification of the homotopy
 perturbation method for solving fractional non-linear equations with
 fractional initial conditions. Sumudu transform is adopted to simplify the
 solution process. An example is given to illustrate the solution process and
 effectiveness of the method.


Evaluation of the impacts of past watershed projects provides useful insights for future projects. In this study, the hydrology and water resources status of Akujan catchment of Qazvin province has been the object of the study which the effects of various measures of watershed managements were evaluated on. For this purpose, the changes of infiltration, water storage, peaks and volumes of catchment floods, were compared before and after the implementation of watershed management projects. The results show that 115000 m3 more runoff storage has been carried out by watershed management operations that 19.4% of this volume is related to the structural operations and 80.6% of it is due to biological and biomechanical projects of the catchment. Results of the flood analysis indicate that the role of structural measures in the change time of concentration of the catchment is low and at times even negative. Therefore the reduction of the peak flow and flood volume at the outlet of catchment is due to the implementation of biological and biomechanical measures which reduces the peak flows 42.7, 25.4, 20.8, 17.1, 15.3, 13.8% and flood volumes, 41.8, 24.8, 20.2, 16.5, 14.8, 13.3% respectively for the return periods of 2, 5, 10, 25, 50 and 100 years. Another observation is that the effect of watershed management practices on the reduction of flood peak and volume decreases when the return period of flood is increased.
Keywords: water storage, flood control, peak flow, flood volume, biological and biomechanical, structural operations.


Up to 30% of European HIV‐positive patients tested for hepatitis C virus (HCV) are seropositive. All co‐infected patients with chronic HCV and ≥F2 fibrosis should be considered for HCV therapy given their increased risk of death from liver disease. Despite this the extent to which co‐infected patients initiate HCV treatment is not well described. The aims of this study were to determine the rate of HCV treatment uptake among co‐infected patients and to estimate the effect of treatment on all‐cause and liver‐related death. EuroSIDA patients positive for HCV antibody and HCV‐RNA were included in the study. Baseline was defined as the date of recruitment or HCV seroconversion, whichever occurred later. Poisson regression was used to identify temporal changes and regional differences in HCV treatment uptake (use of at least interferon‐α [peg‐IFN]± ribavirin) and to study the association between HCV treatment and progression to all‐cause and liver‐related death. 1947 patients were included, with a median follow‐up time of 107 months (IQR: 57–156). Overall 456 (23.4%) of HIV/HCV co‐infected patients have received HCV therapy so far. The incidence of HCV treatment rose from 0.29 (95% CI: 0.13–0.45) per 100 person‐years follow‐up in 1998 to 5.26 (95% CI: 3.87–65) in 2007, before falling to 3.73 (95% CI: 2.40–5.06) in 2009. There were considerable regional differences (Figure). In a multivariable model treatment incidence increased 11.0% (95% CI: 4.0–18.4; p=0.0016) per 2 calendar years. Patients with CD4 cell counts greater than 350 cell/mm3 (incidence rate ratio [IRR]: 1.75 [1.37–2.23; p < 0.0001]), HIV‐RNA less than 500 copies/ml (IRR: 1.58 [1.18–2.12; p=0.0023]), with HCV genotype 3 (IRR: 1.55 [1.21–1.98; p=0.0006]) compared to genotype 1) and those from south (IRR: 1.99 (1.45–2.72; p<0.0001) and east central Europe (IRR: 1.61 [1.11–2.34; p=0.011]) compared to west Europe, were more likely to initiate treatment. In a multivariable model treatment for HCV was not significantly associated with all‐cause death (355 deaths, IRR: 0.81 [95% CI: 0.54–1.19; p=0.28]) or liver‐related death (95 deaths, IRR: 1.0 [95% CI: 0.50–2.02; p=0.99]). The incidence of treatment for HCV among co‐infected patients increased from 1998 until 2007 and was common in those with higher CD4 cell counts and lower HIV‐RNA, consistent with HCV treatment guidelines. HCV treatment was not associated with all‐cause or liver‐related death in this population.


Patent number: EP Appl. Reference LPI-PATENT-2007-003Search for this record at the European Patent Office Record created on 2007-12-05, modified on 2016-08-08


Purpose
Metropolitan areas suffer from frequent road traffic congestion not only during peak hours but also during off-peak periods. Different machine learning methods have been used in travel time prediction, however, such machine learning methods practically face the problem of overfitting. Tree-based ensembles have been applied in various prediction fields, and such approaches usually produce high prediction accuracy by aggregating and averaging individual decision trees. The inherent advantages of these approaches not only get better prediction results but also have a good bias-variance trade-off which can help to avoid overfitting. However, the reality is that the application of tree-based integration algorithms in traffic prediction is still limited. This study aims to improve the accuracy and interpretability of the models by using random forest (RF) to analyze and model the travel time on freeways.

Design/methodology/approach
As the traffic conditions often greatly change, the prediction results are often unsatisfactory. To improve the accuracy of short-term travel time prediction in the freeway network, a practically feasible and computationally efficient RF prediction method for real-world freeways by using probe traffic data was generated. In addition, the variables' relative importance was ranked, which provides an investigation platform to gain a better understanding of how different contributing factors might affect travel time on freeways.

Findings
The parameters of the RF model were estimated by using the training sample set. After the parameter tuning process was completed, the proposed RF model was developed. The features' relative importance showed that the variables (travel time 15 min before) and time of day (TOD) contribute the most to the predicted travel time result. The model performance was also evaluated and compared against the extreme gradient boosting method and the results indicated that the RF always produces more accurate travel time predictions.

Originality/value
This research developed an RF method to predict the freeway travel time by using the probe vehicle-based traffic data and weather data. Detailed information about the input variables and data pre-processing were presented. To measure the effectiveness of proposed travel time prediction algorithms, the mean absolute percentage errors were computed for different observation segments combined with different prediction horizons ranging from 15 to 60 min.


With the development of higher vocational colleges by leaps and bounds,and the continuous deepening of the reform of personnel system,the problems faced by the work of personnel files are more complex.We should adopt to strengthen leadership,standardize management,innovative management models,promote effective information management to optimize the value of personnel files.


Analysis of Constant force hangs the structure,established the constant force hang the organization optimization mathematical model,the spring optimizes the mathematical model.Using the MATLAB genetic algorithm tool,optimizes the organization parameter,the spring parameter,after the contrast in the performance aspec(tconstancy)the remarkable enhancement,in the economic efficiency aspect,cost reduction,the effect is obvious.Meanwhile has provided the beneficial reference to other mechanical product design.


A digital drift chamber digitizer system has been developed for use in a PEP experiment. The system is packaged 8 channels to a # 1 CAMAC module, and features real time digitization, 5 ns time binning, automatic data compression, and access to wire hit information for use by an external fast trigger processor. The modules are operable in an autonomous digitizer crate with a special digitizer controller, or in a standard CAMAC crate for testing, and incorporate extensive system test and debugging aids.


Infrared thermography, as a remote imaging system, is a powerful tool of nondestructive evaluation. Unfortunately, it has some limitations when dealing with deep and low thermal resistance defects as in the case of thick walls of historic buildings and buried anthropic remains, which are important tasks of the cultural heritage field. Thus, it is evident the need of relatively high-depth inspection techniques such as the geophysical methodologies. The present study is concerned with the combined use of infrared thermography and geophysical methods in the conservation of architectural structures and art treasures. The main purpose of this study was to characterize the overlapping zone from low-to-high depth with the two different methodological approaches. The investigation was carried out on laboratory specimens, which were two-component structures including a plaster layer over a support of marble, brick, or tuff. Air bubbles were intentionally created inside each specimen to simulate detachments. Measurements were performed with infrared thermography and electric-type geophysical methods. Results prove that an integrated use of the two techniques supply also a detailed evaluation of the structure degradation as well as information about the related causes of degradation.


Procedures have been developed for sampling the geometry of fractures in underground coal mines. Stratified cluster sampling and the unit area concept are applied to the collection of fracture orientation data. The use of unit area mapping, stratification, and site delineation is made to assure collection of representative data. The procedures developed help to isolate sources of variability in the fracture patterns.


Should public schools go out looking for private philanthropy? The question was sharply posed by the release earlier in the week of a survey of giving to and receiving by schools. It found , unsurprisingly, that the lion's share goes to non-government schools, the independents particularly.


Abstract  Carbonate breccias occur sporadically in the Lower–Middle Ordovician Maggol Limestone exposed in the Taebacksan Basin in the northeastern part of the northeast–southwest‐trending Ogcheon Belt, South Korea. These carbonate breccias have been previously interpreted as intraformational or fault‐related breccias. Thus, little attention has been focused on tectonic and stratigraphic significance of these carbonate breccias. The present study, however, indicates that the majority of these carbonate breccias are solution–collapse breccias, which are causally linked to paleokarstification. Carbonate facies analysis in conjunction with conodont biostratigraphy suggests that an overall regression toward the top of the Maggol Limestone probably culminated in subaerial exposure of platform carbonates during the early Middle Ordovician (earliest Darriwilian). Extensive subaerial exposure of platform carbonates resulted in paleokarst‐related solution–collapse breccias in the upper Maggol Limestone. This subaerial exposure event is manifested as a major paleokarst unconformity at the Sauk–Tippecanoe sequence boundary elsewhere beneath the Middle Ordovician succession and its equivalents, most notably North America and North China. Due to its global extent, this paleokarst unconformity has been viewed as a product of second‐ or third‐order eustatic sealevel drop during the early Middle Ordovician. Although a paleokarst breccia zone is recognized beneath the Middle Ordovician succession in South Korea, the Sauk–Tippecanoe sequence boundary appears to be a conformable transgressive surface on the top of the paleokarst breccia zone in the upper Maggol Limestone. The paleokarst breccia zone beneath the conformable transgressive surface is represented by a thinning‐upward stack of exposure‐capped tidal flat‐dominated cycles that are closely associated with multiple occurrences of paleokarst‐related solution–collapse breccias. This paleokarst breccia zone was a likely consequence of repeated fourth‐ and fifth‐order sealevel fluctuations. It suggests that second‐ and third‐order eustatic sealevel drop may have been significantly tempered by substantial tectonic subsidence near the end of the Maggol deposition. The tectonic subsidence in the basin is also evidenced by the occurrence of coeval off‐platform lowstand siliciclastic quartzite lenses as well as debris flow carbonate breccias (i.e. the Yemi Breccia). With the continued tectonic subsidence, subsequent rise in the eustatic cycle caused drowning and deep flooding of carbonate platform, forming a transgressive surface on the top of the paleokarst breccia zone. This tectonic implication contrasts notably with the slowly subsiding carbonate platform model for the basin as has been previously interpreted. Thus, it is proposed that the Taebacksan Basin in the northeastern part of the Ogcheon Belt evolved from a slowly subsiding carbonate platform to a rapidly subsiding intracontinental rift basin during the early Middle Ordovician. The proposed tectonic model in the basin gives much better insight to unravel the stratigraphic response to tectonic evolution of the Ogcheon Belt, which remains an enigmatic feature in formulating a tectonic framework of the Korean peninsula. The present study also provides a good example that the falling part of the eustatic sealevel cycle may not produce a significant event in a rapidly subsiding basin where the rate of eustatic fall always remained lower than the rate of subsidence.


An artificial neural network based on experimental data from the process of epoxidation of soybean oil with epoxidizing system: hydrogen peroxide / acetic anhydride / catalyst was created. This allows you to select the optimal parameters, control the epoxidation process at the stage of synthesis and improve the technology of epoxidized products. A method for calculating the results of epoxidation of mixtures of unsaturated compounds has been developed. It allows to control the epoxidation process at the stage of synthesis and to improve the technology of obtaining epoxidized products. The obtained optimal conditions of the epoxidation process are adequate for other vegetable oils.


Based on the theory of epipolar slope matching, this paper proposes a new method of rapid ambiguity\|avoiding feature matching which can be used to solve the problem of ambiguity in matching effectively considering the trait of the inspection system of multi\|view stereo vision.


An alkyl silane layers on the hydroxylated surface of the glass substrates were prepared via the method of self-assembled monolayers(SAMs),Hf(SO4)2·4H2O and HCl were used as raw materials,HfO2 thin films were prepared on the active groups of the alkyl silane by the liquid phase deposition(LPD).water contact angle of OTS-SAMs irradiated by UV light was studied.The surface configuration and structure of the thin films were characterized and analyzed by water contact angle equipment,AFM,SEM and XRD.The results of the characterization indicate that the HfO2 thin films were successfully prepared by the self-assembled monolayers,and the thin films were uniform and dense with a cubic microstructures of HfO2.


Half of all employee turnover in the U.S. is involuntary. Perhaps due to the mistaken as-sumption that only poor performers are fired, research has largely neglected the subject of involun-tary tur...


Review of   Leach, S., & Tartaglia, J. (2018). The Meaning of Life and the Great Philosophers. Routledge: London, & New York


Semiotic aspect of transformation of V. V. Majakovskiy"s poetic ideology from the early period of creative work to the late is analyzed in the article.


Acrylamide exposure through environment pollution and diet is very common in daily life. With the deepening of the study on the toxicity of acrylamide, it has attracted widespread attention for the effects of acrylamide on multiple organs through affecting a variety of programmed cell death. Multiple studies have shown that acrylamide could exert its toxic effect by inducing programmed cell death, but its specific molecular mechanism is still unclear. In this review, the research on the main forms of programmed cell death (apoptosis, autophagy, and programmed necrosis) induced by acrylamide and their possible mechanisms are reviewed. This review may provide basic data for further research of acrylamide and prevention of its toxicity.


Taking supervision works of the sixth contract segment in Qihe-Xiajin section of Qing-Yin expressway as example the importance of engineering quality supervision of expressway is discussed,at the same time corresponding method and measures are proposed for quality supervision and control in order to improve engineering quality of expressway.


Security has become one of the major concerns in mobile adhoc networks (MANETs). Data and voice communication amongst roaming battlefield entities (such as platoon of soldiers, inter-battlefield tanks and military aircrafts) served by MANETs throw several challenges. It requires complex securing strategy to address threats such as unauthorized network access, man in the middle attacks, denial of service etc., to provide highly reliable communication amongst the nodes. Intrusion Detection and Prevention System (IDPS) undoubtedly is a crucial ingredient to address these threats. IDPS in MANET is managed by Command Control Communication and Intelligence (C3I) system. It consists of networked computers in the tactical battle area that facilitates comprehensive situation awareness by the commanders for timely and optimum decision-making. Key issue in such IDPS mechanism is lack of Smart Learning Engine. We propose a novel behavioral based "Smart MultiInstance Multi-Label Intrusion Detection and Prevention System (MIML-IDPS)" that follows a distributed and centralized architecture to support a Robust C3I System. This protocol is deployed in a virtually clustered non-uniform network topology with dynamic election of several virtual head nodes acting as a client Intrusion Detection agent connected to a centralized server IDPS located at Command and Control Center. Distributed virtual client nodes serve as the intelligent decision processing unit and centralized IDPS server act as a Smart MIML decision making unit. Simulation and experimental analysis shows the proposed protocol exhibits computational intelligence with counter attacks, efficient memory utilization, classification accuracy and decision convergence in securing C3I System in a Tactical Battlefield environment.


The main purpose of the paper was to introduce some thermal density flow observations and some statistical analysis results,and to suggest to take proper sediment outflow mode in the practical applications according to different situations: if the mean daily discharge over 100 m3/s,or the sediment charge over 100 kg/m3 in June or Sept.,exhausting floods should be taken to make the erode and siltation balance.With regard to other floods occurring in June or Sept.,turbidity current should be chosen to reduce the siltation in reservoir area.


Abstract Elemental profiling is a process where element concentrations in tissues are used to discern group membership between a priori groups, such as geographic location. The goal of this meta-analysis was to determine the effectiveness of elemental profiling to discern the geographic origin of seafood products when coupled with discriminant analyses. Cohen's Kappa of discriminant analyses were calculated based on reported accuracies and calculated expected accuracies. A systemic literature review was conducted which generated 86 effect sizes from 43 studies. A random effects model was used to estimate Cohen's Kappa, and the average effect observed was 0.83 (±0.036 95% CI) with a p value of <0.001. Moderators were investigated as part of this analysis. There were no significant differences based on production method or geographic range, but differences were observed based on the type of tissue analyzed and taxa groups. Meta-regression was used to analyze the relationship between the effect size and the number of elements included in each analysis or sample size. There was no observed relationship between Kappa and the number of elements analyzed or the sample size of the study. Based on these results, recommendations for future studies that utilize elemental profiling are included.


The aim – to compare hemodynamic profiles in children during central and peripheral blocks of abdominal wall. Materials and methods. The study included 168 children aged from 1 month to 5 years, who underwent abdominal wall surgery under regional anesthesia with sedation (caudal block (n=28), thoraco-abdominal paravertebral block in Th 12 -L 1 level (n=49), transverses abdominal plane (ТАР) block (n =50), blockade of ilioinguinal-iliohypogastric nerves (n=41) with 0.25% bupivacaine. The hemodynamics (systolic, diastolic and mean blood pressure and pulse rate) were analyzed perioperatively. Results .Hemodynamics during all regional anesthesia techniques were stable. Caudal block was accompanied with mild decrease in blood pressure and heart rate, no reaction on peritoneum traction and had hyperdynamic response in postoperative period. Paravertebral block had similar intraoperative hemodynamic profile, but had no increase in blood pressure and heart rate after surgery. TAP-block and ilioinguinal-iliohypogastric nerve blocks showed hyperdynamic response to peritoneum traction and no hyperdynamia after surgery. Conclusions . In comparison with caudal and paravertebral anesthesia TAP-block and ilioinguinal-iliohypogastric nerve blocks accompanied with sympathetic activation in response to peritoneum traction. Caudal block has shorter duration than perip heral blocks.


. One hundred and eight patients with myocardial infarction have been investigated 1–1 1/2 year after the acute attack. As a control group 44 coaeval hospital patients with no known ischaemic heart disease and 65 healthy young subjects were examined.

Significantly higher values were found for plasma total lipid, triglyceride, cholesterol, and phospholipids in the coronary patient group as compared with the coaeval hospital control group, and in the last mentioned group as compared with the young controls.

Paper electrophoretic lipoprotein estimations were carried out in all cases. 15.9% of the hospital control group and 42.6% of the coronary patient group had Type II hyperlipoproteinaemia. Hyperlipoproteinaemia with increased pre-β-fraction was found in 34.1% and 35.2% respectively of the same groups. Analyses of the occurrence of pre-β-lipoprotein fractions in all three groups seem to suggest the existence of two different populations according to the metabolism of endogenous triglycerides. We think that this fact must be taken into consideration in future dietetic trials with the aim of preventing ischaemic heart disease.


The development of autonomy is acknowledged as a significant educational goal in language education, but it seems challenging in many schools. One of the reasons for this discrepancy is the lack of professional development addressing teacher beliefs and practices about learner autonomy (LA) as valid educational concerns. However, in teacher education research, limited attention has been paid to language teachers' understandings and practices of promoting LA. Hence, this research project aims to develop in-service teachers' beliefs, understandings, and practices about LA through teacher development workshops. First, an in-depth interview was used to gather five teachers' beliefs about autonomy and teaching practices in secondary schools. Second, two workshops were conducted based on the literature and the initial interview to develop teachers' LA-related beliefs, understandings, and practices. Third, a post-workshop evaluation was conducted through a focus group, the written reflection, and the researcher's self-reflective journals to examine to what extent teachers' knowledge and beliefs about LA have changed and developed. The findings revealed that the online workshops have made making teachers more aware of the concept of LA and its significance in language learning. Their LA-related beliefs and understandings of their teaching objectives, prior learning experiences, and teaching competence influenced their LA-related classroom practices. Some practical suggestions were provided for designing and implementing professional development workshops.


Q235 steel was treated by Plasma electrolytic carbonitriding technique in formamide- ethanolamine solution. The formation conditions of carbonitriding were determined through XRD analysis, the phase compositions of samples treated under different conditions were studied. The diffused was layer was observed by SEM and its micro-hardness was measured .The results showed that the compositions of diffused layer were different under different voltages; The diffused layer was mostly constituted of α-Fe, Fe3C,Fe5C2, e-Fe2-3N, and γ-Fe; The diffused layer of 50μm can be obtained under 150 V, 0.5 min and its maximum micro-hardness can reach 720 HV0.1.


This article presents Thomas Sharp's contribution, a glance to the past with the objective of rescuing valid ideas to face sustainable urban development. His contribution is known fundamentally for his protection of the role that urban form should play in planning. Nevertheless, the impact of his plans for historic cities, such as Oxford, Exeter and Durham, should not hide the interest and the ambition of his first approaches, very well reflected in his first publication, Town and Countryside . In this book Sharp's proposal for facing planning goes beyond the scope that comes off his most known works.


Introduction: Iron deficiency is a major health problem worldwide affecting more than a quarter of the world's population. Iron deficiency anemia (IDA) is the most common form of anemia affecting 43% of the world's children. Iron deficiency is defined as a condition in which there are no mobilizable iron stores and in which signs of a compromised supply of iron to tissues, including the erythrocytes, are noted. The more severe stages of iron deficiency are associated with anemia. When individual hemoglobin levels are below two standard deviations (2SD) of the distribution mean for hemoglobin in an otherwise normal population of the same gender and age who are living at the same attitude, iron deficiency anaemia is considered to be present. In infants and children with iron deficiency, there is evidence of impaired motor development and coordination; impaired language development and scholastic achievements; psychological and behavioral effects (inattention, fatigue, insecurity, etc.). In addition, there is decreased physical activity in iron deficient children. The adverse effects on cognitive and educational test performance due to IDA in preschool and school-age children appear more transitory in nature than the effects on development in infants and imply that treatment of IDA in preschool and school-age children through iron supplementation programs may be beneficial and have immediate effects. This is in contrast to the effects of IDA on infants, for whom poorer performance on developmental tests may not be reversible with treatment and where programs aimed at the prevention of IDA may be the most appropriate action. Aims and Objectives: 1.To assesses the scholastic performance in relation to iron deficiency in school going children. 2. To assess the impact of iron supplementation on scholastic performance in these children. Materials and methods: All children aged between 5 to 10 years at a government aided school in Bellary for a period of one academic year (2011-12) were included in the study. Consent was taken from the parents. History and clinical examination was done using a systematically designed proforma. CBC and Serum ferritin were done in all children. Those children who were found to be iron deficient as per WHO criteria were dewormed and supplemented with iron. Children were assessed for school performance, by reviewing the school records prior to and after iron supplementation. Results: A total of 186 children were screened, out of which 13.4% had iron deficiency anemia. 19.3% children had iron deficiency without anemia. Following iron supplementation, 48% of anemic children showed improvement the grades (p<0.05), 44.4% children in the iron deficiency without anemia group showed improvement in the grades (p<0.05), whereas 6.3% of the non anemia, non iron deficiency group showed improvement in grades. Iron deficiency is a cause of poor school performance, which improves with treatment.


The tetralogy The State of Lefebvre (1976-8), is among his works the least known. However, The State synthesizes most of Lefebvrian theories and concepts. For example: spa-ce, city and urban, Marxism, language, nation and - of course - daily life, which we will use here as a counterpoint. In an attempt to examine our modernity, Lefebvre has studied the alie-nations that weigh on daily life in relation to the powers of the capitalist market and the state. The self-managed project, which is present throughout the work, will provide the glimpse of a path of liberation from human possibilities. The concept of self-management will be central (to speak as Fourier) between urban life, daily life and state criticism, as well as a mediation between theory and practice. Again, Lefebvre has not separated his metaphilosophy from a revolutionary policy capable, through self-management, of deepening democracy and changing daily life.


IN "rnesE DAYS of changing concepts of many diseases it is well to review the experience of medical clinics and teaching institutions toward the objective of arriving at more logical approaches to the management of diverticular disease of the colon. T h e term "diverticular disease" was introduced by Rosser~a in 1955. For years it was believed that diverticulosis possessed little clinical significance and only when the diverticula became involved by inflammatory changes did the condition become a disease entity. Although diverticulitis has been managed medically for years and surgical operat ion has been reserved for complications, recent reports indicate that surgical t reatment is being utilized more frequently when there are rio complications. T h e classification of diverticulitis, diverticulosis and diverticulitis with complications into three separate clinical entities requir ing different methods of management is not justifiable. T h e three conditions should be considered manifestations of the same process. If this concept is acceptable management of the condition should be based on the same basic principles, regardless of the stage of the disease. Advancement in surgical technic, preoperative and postoperative care, anesthesia and ancillary factors in the care of patients dur ing recent years have led to a more liberal at t i tude on the part of many surgeons


To quantify poverty merely monetary approach does not provide a true representation of deprivations or wellbeingness of households. Multidimensional Poverty Index measures multiple dimensions of deprivation of poverty that gives a more complete picture of poverty. For the study MPI status of Haryana and India as a whole the secondary data on India National Multidimensional Poverty Index, Baseline Report, Based on National Family Health Survey-4 (NFHS) 2015-16 published in 2021 has been used. Main objective of the paper is to study the status of Multidimensional Poverty Index of India and the position of Haryana as it's in top states with respect to per capita income from 2006 to 2021. The district wise deprivation and counting of different types of deprivations that individuals experience at the same time has been discussed. The study observed that Haryana stands in better position in Multidimensional poverty index (value 0.055) and less deprived in all the indicators of three dimensions of Multidimensional poverty index compare the average status of India as a whole (0.118). District level results revealed the district Mewat, Palwal, Sirsa and Rohtak, Mahendragarh have higher level of multidimensional poverty districts whereas Ambala stands at first rank in lowest head count ratio 1.99%, followed by Panchkula with 2.47%. Comparatively in third dimension of MPI status of Haryana is far better like in electricity. Its deprivation is 0.75 percent compare to 8.29 percent in India. Results show that there is inter district disparity among the indicators which has been reduced. Few districts are above in all indicators due to economic factors and few are deprived in all indicators like Mewat , which is just 58 km far from millennium city of India. Status of health, education and standard of living is worsening in Mewat. Causes are many Like Religion, political, socio orthodox and Illiteracy.


The TAT protocols of 30 sexually abused female children and 30 female children with no documented history of abuse were analyzed using the Scoring Scheme for the TAT and Other Verbal Projective Techniques (Fine, 1955). No significant differences were found between groups on mean number of negative feelings portraited in the TAT stories. Similarly, no significant differences were found between groups on mean number of unfavorable outcomes to TAT stories. However, when specific feelings were considered, subjects in the sexual abuse group showed a significantly higher incidence of reference to guilt and sexuality. These results were independent of age, race, and intelligence.


A can be separated volatile condensable components of the vapor from the last stage of to generate vacuum and melt phase polycondensation, the conventional compared to art methods reduce the vapor volume and the monomer and oligomer deposits It provides a method to avoid the failure that caused by. SOLUTION This object is in the reactor to be reduced pressure, one or more vapor jet device that is attached to the spray condenser located upstream or downstream are connected with the suction side, when the phenol or phenol-containing vapor having a pressure of 0.5hPa~ about 1.5MPa as the driving vapor liquid phenol or phenol-containing solution as used and sprayed material is resolved by used.


Component A and component B are provided to the laminated flexible packaging material comprising a mixture is a two component adhesive. Component A comprises an isocyanate-functionalized compound. Component B comprises a mixture of a polyol with high functionality having at least four hydroxy groups per molecule and a polyol trifunctional containing at least two primary OH groups on the molecule and on the molecule two secondary OH groups and three OH groups on the molecule. Component B may also contain a bifunctional polyol containing two OH groups on the molecule. The adhesive is solid and different from the conventional laminating adhesives used in the same mixing ratio: B mixing ratio when used in maintaining the desired properties.


There are various causes of possible upper airway obstruction in infants. Particularly, large cysts on the base of tongue may cause severe airway obstruction by a mass effect on the hypo pharynx and by displacing the epiglottis of these basal lingual cysts, thyroglossal duct cyst is rare but occasionally its remnants can be found at the base of the tongue. We report successful management of paediatric airway in a two month old infant with a thyroglossal duct cyst scheduled for cyst excision.


Bi-directional optical flow (BDOF) is an efficient coding tool that has been recently adopted into Versatile Video Coding (VVC) standard. With BDOF, bi-predictive prediction samples of one coding block are enhanced via higher-precision motion vectors (MVs) derived from its two reference blocks. In this way, the energy of prediction error could be reduced, resulting in better coding performance. In VVC, the derived motion information is only used to enhance prediction samples. In this paper, it is proposed to use the derived motion information to also refine decoded MVs. The refined MVs may be used as spatial motion vector prediction (MVP) for the following coding units (CUs), as the temporal MVP for the subsequent pictures, and in the deblocking filtering process. Furthermore, the refined MVs can be used to perform motion compensation (MC) again to further improve the quality of the prediction samples. Simulation results show that the proposed methods can achieve -1.18% BD-rate saving in average under the random access configuration on top of the existing BDOF design in VVC.


Vildagliptin is the first in a new class of oral antidiabetic agents known as dipeptidyl peptidase IV inhibitors(DPP-Ⅳ) or "incretin enhancers".Vildagliptin works by inhibiting DPP-Ⅳ,an enzyme that breaks down GLP-1.By delaying the degradation of GLP-1,vildagliptin extends the action of insulin while also suppressing the release of glucagon.This leads to a reduction in elevated blood glucose levels(hyperglycaemia) that is a characteristic feature of type 2 diabetes.Clinical results indicated that vildagliptin produces clinically significant reductions in HbA1c when used as monotherapy and in combination with other anti-diabetes agents.In general,the drug has proved to be well tolerated with low rates of hypoglycaemia and gastrointestinal side effects and no weight gain or oedema.This review presents the mechanism of action,pharmacokinetics,clinical studies and drug adverse reactions of vildagliptin.


Coronary artery bypass graft (CABG) has been the first option for revascularization in multiple vessel coronary artery disease. One of the most major obstacles after CABGs is atherosclerotic changes of SVGand more than 50 percent ofSVGare occluded at 10 years and 25 percent show severe stenosis at angiographic follow-up. Whether native vessel percutaneous coronary intervention (PCI) on native vessel or saphenous vein graft intervention is of benefit in these patients is still a debate. In this case report we want to clarify a common clinical scenario in a patient with prior CABG seven years ago which a proper decision in the right time could save many futile efforts. The patient underwent 7 PCI on the diseased SVG on OM with frequent occlusion due to stent thrombosis and in-stent restenosis which finally native vessel antegrade CTO PCI alleviated the problem and patient followed up 2 months after the procedure without any chest pain in his ordinary


Superconducting magnetic systems permit increasing observing frequencies for NMR experiments. The sensitivity and range of application of the single‐layer detection system is evaluated. High measuring frequencies demand new detection systems because the conventional detection systems lose their good features above about 100 MHz. In this paper a new detection system is presented. The slotted tube resonator (STR) is suitable for all intensities of magnetic field which will be produced in the near future. The characteristic parameters of the STR are calculated and the construction is described in detail. Theoretical sensitivity considerations are compared with practical measurements.


The article tells instructive stories that might be useful for discussingthe optimal moral choice for both future doctors and their patients. The author consider morality through a system of values that reminds that a part cannot be larger than the whole, re-spectively, a person as part of a social organism finds a harmonious existence with the whole through moral reflection, personally choosing between benefit and harm, between good and evil.


We present a novel processor architecture designed specifically for use in low-power wireless sensor-network nodes. Our sensor network asynchronous processor (SNAP/LE) is based on an asynchronous data-driven 16-bit RISC core with an extremely low-power idle state, and a wakeup response latency on the order of tens of nanoseconds. The processor instruction set is optimized for sensor-network applications, with support for event scheduling, pseudo-random number generation, bitfield operations, and radio/sensor interfaces. SNAP/LE has a hardware event queue and event coprocessors, which allow the processor to avoid the overhead of operating system software (such as task schedulers and external interrupt servicing), while still providing a straightforward programming interface to the designer. The processor can meet performance levels required for data monitoring applications while executing instructions with tens of picojoules of energy.We evaluate the energy consumption of SNAP/LE with several applications representative of the workload found in data-gathering wireless sensor networks. We compare our architecture and software against existing platforms for sensor networks, quantifying both the software and hardware benefits of our approach.


717 Figure 1 AMG 160 treatment extended survival in mouse models of advanced prostate cancer Conclusions Our study demonstrates potent antitumor activity of AMG 160 monotherapy in models of metastatic CRPC that Abstracts J Immunother Cancer 2020;8(Suppl 3):A1–A559 A429 on M ay 6, 2021 by gest. P rocted by coright. http/jitc.bm jcom / J Im m unther C acer: frst pulished as 10.11jitc-2020-S IT C 20.0715 on 10 D ecem er 220. D ow nladed fom


Introduction: Lung cancer (LC) is becoming more and more common in women where it presents significant differences at both clinical and therapeutic levels. Objectives: Evaluate clinical, therapeutic and prognostic features of LC in female patients. Methods: Our study include164 patients witch were treated for LC between 2006 and 2013: 29 women (G1) and 135 men (G2). These two groups (G1 and G2) were compared (age, past history, interventions, TNM stage and long term survival). Results: Mean age of patients was 62 years in the 2 groups. Smoking is significantly higher in G2 (97% vs 18,5%; p Conclusion: Because less comorbidities, better PS and better chemosensitivity female patients with LC have better prognosis.


The conformation of the DNA helix is supposed to be a critical element in site‐specific recognition by ligands both large and small. Groove width is one important measure of the conformation which varies with the local nucleotide composition, perhaps because of the presence of a purine 2‐amino group on G.C base pairs. We have probed DNA with G‐‐>inosine (I) and/or A‐‐>diaminopurine (DAP) substitutions to see whether the location of the purine 2‐amino group can indeed affect the minor groove width. At acid pH, the reactivity towards uranyl nitrate is modulated in substituted DNA quite differently from natural DNA, consistent with a marked narrowing of the minor groove at sites of G‐‐>I substitution and widening at sites of A‐‐>DAP replacement. The latter exerts the dominant effect. The expected changes in conformation are equally evident in the patterns of susceptibility to DNase I cleavage, but not to hydroxyl radical attack. Nuclease cleavage is maximal in normal and substituted DNA at regions of inferred moderate groove width which are generally little affected by the nucleotide substitutions. Consistent with models of sequence‐dependent cutting by DNase I we find that the presence of a purine 2‐amino group on the base pair three places upstream of the cutting site has a profound influence on the rate of reaction.


Abstract : There are many well-known sources of nonlinearity present in hyperspectral imagery; these include bi-directional reflectance distribution function (BRDF) effects, multi-path scatter between heterogeneous pixel constituents, and the variable presence of water, an attenuating medium, in the scene. In recent publications, we have presented a data-driven approach to representing the nonlinear structure of hyperspectral imagery. The approach relies on graph methods to derive geodesic distances on the high-dimensional hyperspectral data manifold. From these distances, a set of manifold coordinates that parameterizes the data manifold is derived. Because of the computational and memory overhead required in the geodesic coordinate calculations, the approach relies on partitioning the scene into subsets where the optimal manifold coordinates can be derived in an efficient manner, followed by an alignment stage during which the embedded manifold coordinates for each subset are aligned to a common manifold coordinate system. We demonstrated the feasibility of the coordinate and alignment methodology and the ability of the manifold approach to provide higher data compression and more effective classification when compared with linear methods. In this paper we develop an improved approach to the manifold coordinate alignment phase with an improved sampling methodology. Results are demonstrated using examples of hyperspectral imagery derived from PROBE2 hyperspectral scenes of the Virginia Coast Reserve barrier islands.