Motivated by the need for more accurate and robust weather forecasts, multimodel superensembling has become a widely researched topic. We propose an approach for multimodel superensembling using convolutional neural networks to perform merging of weather models based on local weather events. Our system is trained on medium range global wind forecasts and shows an average RMSE improvement of 7.3% compared to the ensemble mean.


In this study antibiotic resistance pattern of E. coli and coagulase positive Staphylococcus aureus isolated from honey bees digestive tract of Shahrekord apiaries were studied. From 45 isolated E. coli strains 35 isolates (77.77%) were resistant to one or more antibiotics. The most resistance pattern were to Erythromycin (77.77%), followed by 14 isolates to Nitrofurantoin (31.11%). From 22 isolations of S. aureus resistance to Penicillin and Erythromycin were 18 (85.71%) and 11 (50.00%) isolates, respectively. Number of isolations in two seasons (fall and spring) was statistically significant (P<0.005), but profile of the antibiotic resistant of the two bacteria in two seasons are not statistically significant.


In this paper, we discuss the development of Rayleigh-Taylor (RT) filaments in axisymmetric simulations of pulsar wind nebulae (PWN). High-resolution adaptive mesh refinement magnetohydrodynamic simulations are used to resolve the non-linear evolution of the instability. The typical separation of filaments is mediated by the turbulent flow in the nebula and hierarchical growth of the filaments. The strong magnetic dissipation and field randomization found in recent global three-dimensional simulations of PWN suggest that magnetic tension is not strong enough to suppress the growth of RT filaments, in agreement with the observations of prominent filaments in the Crab nebula. The long-term axisymmetric results presented here confirm this finding.


Multi-level government arrangements-federal, state/provincial and local government-are common to all federal systems. However, the place and role of local government in those systems vary markedly. In some, local government is a constitutionally recognised sphere of government, while in others it is merely a competence of the state/provincial government, or an administrative unit of a higher order of government. In some federal systems where it is recognised, like Nigeria, the local governments are principally established for socio-economic and political development at the grassroots. Thus, local governance is the prerogative of the local governments in Nigeria. This tier of government established by Section 7 of the 1999 constitution of the Federal Republic of Nigeria (as amended) has some of its functions detailed in the fourth schedule of the same constitution. The overall objective of this paper is the analysis of the current status of the local government within the Nigerian federal system, and a critical examination of what the future holds for the third tier of government in Nigeria. Using essentially secondary documentary method, with content and thematic analysis, the paper recommends incremental constitutional review (as against mega constitutional renewal), the need to enhance political and economic autonomy of local government through frequent elections, and adopting new strategies for generating internal revenues for the local government in Nigeria.


The doctor is a way of life, which includes monitoring and correction of themself presentation continuously. The physician is one of the socially significant and language-active professions. The language activity of doctors in the Internet is determined by their consciousness and communicative behavior in various genres of social media – a blog, a forum, a social network, a personal website, etc. Evidence indicates that electronic communication can improve health outcomes, for example by promoting professional development, emphasizing self-presentation, and also highlighting linguistic personality of physicians, which is based on verbal-non-verbal behavior. However, discussion of the dangers of these technologies in medicine has overshadowed the consideration of positive applications. Online communication has introduced profound questions about confidentiality, professionalism, and other issues of ethical and legal regulation for healthcare professionals. Understanding that will help to avoid mistakes, thereby maintaining a high level of the doctor's professional image.


The transport of a conservative soluble pollutant along a uniform channel is usually described by means of the well-known Advection-Dispersion Equation. To apply this equation to a practical scenario, the dispersion coefficient value for the reach is required. Since dispersion coefficients cannot be measured in-situ directly from a simple individual measurement, they have to be estimated from available experimental data. In this paper an alternative modelling approach is presented in which the transport of a conservative soluble pollutant in rivers is modelled by means of a non-linear Volterra series. The description of the system by the Volterra series is a generalization of the concept of the linear transfer function, which is of great importance in the analysis of linear systems. Data for this study were derived from a programme of 18 tracer experiments undertaken in the Murray Burn, which is a stream that flows through the Heriot-Watt University Campus at Riccarton in Edinburgh. A two-term nonlinear model was first fitted to the records of breakthrough curves from 10 randomly chosen experiments. Then the performance of the method was assessed by making predictions for the remaining 8 experiments. Predictions from a cascade of continuously stirred tank reactors and from Fischer's routing procedure were also obtained. The results obtained indicate that generally the simple nonlinear model gives better results than those obtained by the routing procedure and that it gives marginally better results than the cascade model. nonlinear Volterra series model in the form of a sum of convolution integrals, and a Fischer's routing procedure with dispersion coefficients determined by means of a Multi-Layer Perceptron Artificial Neural Network or via linear regression. 2 MURRAY BURN EXPERIMENTS Between 1999 and 2001, 26 tracer experiments were performed on the Murray Burn, which is a small river that flows through the Heriot-Watt University Campus at Riccarton in Edinburgh. These experiments were undertaken at various flow rates in a 540m long reach. Each experiment consisted of the release of a tracer (Rhodamine WT) followed by the collection of tracer concentrations at up to 4 cross-sections. The tracer was injected to the river at the same place each time. In the first few experiments concentration measurements were collected only at the first two cross-sections, but in the later experiments three or four of the crosssections were used. In a few cases, equipment or human failure led to data not being successfully collected. Further information on the experiments is available in Burke (2002), Wallis and Manson (2005) or Wallis et al (2007). In the present paper models are used to predict the tracer concentration versus time profiles at the second cross-section using concentration measurements at the first crosssection. The distance between these two crosssections is about 137 meters. The data come from 18 experiments, which were considered to contain reliable data. 3 LINEAR DISPERSION MODEL A simple approach to modelling pollutant transport is a cascade of continuously stirred tank reactors as depicted in Fig. 1. This completely mixed system can be used to model pollutant concentration in sub-reaches of a natural watercourse. The mass balance equations for a conservative pollutant can be expressed in terms of concentrations (C), flows (Q) and volumes (V) as: Fig. 1. Cascade of continuously stirred tank reactors


Field-Names, the common and convenient term for minor names which have not achieved the status of place-names, often preserve information important to the historian and to the archaeologist. Their value is well recognized by specialists but not always clearly understood by others. Since field-names are generally found in local, as distinct from national, records, local historians are especially qualified to help in the accumulation of a collection of such names. After a few sentences of advice to secure uniformity of method and to ensure co-ordination, the members of any local historical society, acting as a group or even singly, may build up a valuable collection of field-names. Such work, pursued on systematic lines, would be a real contribution to scholarship, and is already in progress in one or two areas. The following notes attempt to illustrate how the study of field-names may contribute to historical knowledge. They do no more than outline the possibilities and they are confessedly written in the hope that more non-professional Societies will add the formation of a field-name collection to the list of their activities.


In this project, we focused on applications of the new warm-rain and ice microphysics schemes to simulate various cloud systems. The overall goal was either to evaluate and improve specific aspects of the schemes (through comparisons with ARM/ASR observations) or to understand the coupling between aerosols, cloud microphysics and cloud dynamics in variety of situations. These studies are relevant to the indirect impact of atmospheric aerosols on climate. Below we report on selected key aspects of the research and then list all peer-reviewed papers that acknowledge support from this grant. Overall, studies partially supported by this grant resulted in 30 peer-reviewed publications (listed below), several dozens of conference presentations (including posters and oral presentations at the ASR Science Team Meetings), and two PhD dissertations. More detailed summaries of our accomplishments are included in yearly reports. Here we summarize only major efforts. We the approach to TWP-ICE to how convective fluxes and the thermodynamic environment respond over time to perturbations in heating as a way to mimic aerosol impacts previously hypothesized from heuristic arguments, with results to be reported in a future publication. This study shows the existence of different timescales of the response, with relatively rapid adjustment of the environment minimizing the impact of this heating on the convective fluxes over timescales longer than 1-2 days. A study concerning effects of aerosols on supercell convection was reported in Morrison (2012). This study showed considerable sensitivity of aerosol effects on convective dynamics and surface precipitation with alterations to model formulations as well as small perturbations to initial conditions. It was concluded that improved generality and quantification of aerosol effects on deep convective storms is likely to require ensemble methods as well as improved model parameterizations.


An analytical solution for the unified equation for degenerated (pseudo‐) first‐order reactions, e.g., enantiomerization processes, in dynamic CE is presented, and validated with a dataset of 31 250 elution profiles covering typical experimental parameters. The unified equation was applied to determine the enantiomerization barrier of the hypnotic glutarimide derivative thalidomide (Contergan®) by dynamic capillary electrokinetic chromatography (DEKC). The enantiomer separation of thalidomide was performed in an aqueous 50 mM sodium borate buffer at pH 9.3 in the presence of the chiral mobile phase additive carboxymethyl‐β‐CD. Interconversion profiles featuring pronounced plateau formation were observed. Activation parameters ΔH≠ and ΔS≠ were obtained from temperature‐dependent measurements between 20.0 and 37.5°C in 2.5K steps. From the activation parameters the enantiomerization barrier of thalidomide at 37°C under basic conditions were calculated to be ΔG≠ = 93.2 kJ/mol. Comparison of the kinetic data with results obtained at pH 8.0 reveals the catalytic influence of the base on the enantiomerization barrier.


Objective To investigate the linear relationship between invasive blood pressure and noninvasive blood pressure,providing references for clinical blood pressure monitoring.Methods Totals of 32 ICU patients were chosen,and their invasive blood pressure and non-invasive blood pressure were monitored at the same time by self-reflection methods.The data were collected and compared,and linear correlation was analyzed.Results Totals of 98 pairs of valid date were collected.The invasive systolic and diastolic blood pressure were respectively (146.93 ± 21.426) and (71.32 ± 13.152) mm Hg,higher than the non-invasive systolic and diastolic blood pressure which were (124.02 ± 19.417) and (68.86 ± 15.251) mm Hg,and the differences were statistically significant (t =15.301,3.363,respectively; P <0.05).And there was a linear relation between invasive blood pressure and non-invasive blood pressure (r =0.880,P < 0.05).Conclusions There is statistically significant difference between invasive blood pressure and non-invasive blood pressure,which are not substitutable for each other.And non-invasive blood pressure monitoring values can be used to deduce and calculate the invasive blood pressure monitoring values.

Key words:
Blood pressure monitoring;  Invasive blood pressure;  Non-invasive blood pressure; Correlation


The study is to assess the behaviour and impact of various neural network parameters and their effects on the classification accuracy of remotely sensed images which resulted in successful classification of an IRS-1B LISS II image of Roorkee and its surrounding areas using neural network classification techniques. The method can be applied for various defence applications, such as for the identification of enemy troop concentrations and in logistical planning in deserts by identification of suitable areas for vehicular movement. Five parameters, namely training sample size, number of hidden layers, number of hidden nodes, learning rate and momentum factor were selected. In each case, sets of values were decided based on earlier works reported. Neural network-based classifications were carried out for as many as 450 combinations of these parameters. Finally, a graphical analysis of the results obtained was carried out to understand the relationship among these parameters. A table of recommended values for these parameters for achieving 90 per cent and higher classification accuracy was generated and used in classification of an IRS-1B LISS II image. The analysis suggests the existence of an intricate relationship among these parameters and calls for a wider series of classification experiments as also a more intricate analysis of the relationships.


Through using the method of questionnaire investigation,literature and economic analysis,this paper studied the character of supply demand structure of our sports service industry,analyzed the factors influencing level of supply demand.The result showed that with the establishment of socialist market economy,there was big improvement in supply demand structure of our sports service industry.However,traditional system,fund,talent and imbalance development also influenced supply demand of our sports service industry.In order to promote the sustainable development of our sports service industry,some countermeasures should be taken such as system reform,financial diversification,school physical education reform,increasing sports population,cultivation of service talent,establishment of agency.


Objective In order to explore the tissue and sub-cellular distribution of mouse estrogen-enhanced transcript(mEET) protein, we prepared and characterized monoclonal antibodies against mEET. Methods Hybridomas were generated by fusion of Sp2/0 myelomas and spleen cells from rats immunized with mEET recombinant proteins. Hypoxanthine-aminopterin-thymidine-resistant clones were then screened for secretion of antibodies specific for mEET by ELISA and identificated by Western blot. The monoclonal antibodies were subsequently used for studies of tissue distribution and sub-cellular localization of mEET protein by immunofluorescence or immunohistochemistry. Results Four hybridoma cell lines, DA10, DB4, 4A5 and 4D8, were produced, each of which stably secrets antibodies again mEET. Isotyping indicated that they were IgM antibodies. Immunofluorescent assay demonstrated that mEET protein was mainly distributed in cytoplasm, whereas immunochemistry study showed wide tissue distribution with particularly high levels of expression in megakaryocytes in bone marrow. Conclusion The monoclonal antibodies against mEET protein have been successfully prepared, which should provide useful reagent for further investigation into the biological function of mEET.


Subject matter of this thesis is the insolvency proceedings with the emphasis on the continuation of the business activities of the company which had initiated the insolvency proceedings. According to the case-law, over 90 % of the companies which initiated the insolvency proceedings, result in winding-up proceedings and in asset fire sales. Creditors generally receive maximum of 20 % of their claims. Therefore, the case of insolvency proceedings in NAUTA LAMJANA d.d. Kali has been considered in this thesis as an example of a company that had initiated insolvency proceedings and continued with its core business activities during insolvency, with all workers' claims paid in full and closed the insolvency proceedings successfully with the continuation of its business activities. A quality insolvency plan was drafted based on which eventually 50 % of creditors' claims will be settled, and the same creditors have continued with their business cooperation with the shipyard's management up to this date. Thesis is based on data analysis obtained from the insolvency plan as well as from company's business records from years following the closing of the insolvency proceedings.
 Analysis of the publicly disclosed balance sheets of NAUTA LAMJANA d.d. Kali business activities in the last three years which has in the meantime transitioned from joint venture company to a limited liability company, show positive operations balance, while settling the claims relating to the insolvency estate and the insolvency plan. It is the only example of the shipyard in the Republic of Croatia where the ownership has changed from state-ownership to private ownership with all of its liabilities arising from the period when state and workers had full company's ownership. Intra-company collective agreement and workers' rights arising out of it prevented the private owner to reduce costs during recession period via redundancy. The insolvency proceedings and insolvency plan resulted with the business activities operating with rational expenses with regards to the number of employees and all other expenses pertaining to a shipyard.
 This insolvency plan is also an example that a quality management of insolvency proceedings through Creditor's Assembly and Council, given the quality position on the market, can retain the ownership of the company and assure the continuation of profitable business activities.


Loop radiation elements with circular polarization radiation pattern are investigated. The research includes, also, two-dimensional array with loop elements and feeding network on the same dielectric substrate. Simulation for substrate εR =1 gives appropriate radiation pattern and axial ratio (AR). Simulation for substrate εR =2.17 and h= λg/40 gives large deformations of radiation pattern and AR. The reason is surface waves. The surface waves are suppressed perforating the substrate with holes. Radiation array 8×8=64 is realized in the frequency range around 60 GHz.


This report responds to the need of the Air Force to develop new technologies for environmental compliance and site remediation. Effective and efficient treatment of contaminated groundwater is of great importance for Air Force operations, where significant volumes of dilute aqueous waste can be generated and leak into the soil and thence the aquifer. Conventional disposal methods, primarily pump-and-treat, often are impractical or too costly, so that use of aqueous chemical oxidation to treat the contaminants in situ is an attractive alternative for reducing concentrations to acceptable limits.


During the past half century, per-acre maize yields have increased due to improved cultivars, better management, and favorable weather. Recent US biofuel legislation, e.g., revised Renewable Fuel Standard, has increased the demand for bio-fuel and added competition for available cropland. Growth in maize yield may alleviate the potential impacts, including greenhouse gas effects, of rising food, feed, and fuel demand. Using 1960-2009 maize yields for the United States and top maize-producing states, we test for structural breaks and develop yield trend and growth forecasts for 2030. Depending on the forecasting model, US maize yield ranges from 205 to 242 bushels per acre in 2030. Holding maize production constant at the 2009 level, 16-25 million acres could be shifted to other crop production. Maize yield forecasts are sensitive to model choice (linear trend vs. growth rate) and time period (short- vs. long-run trends). Ultimately, maize yield growth and trends have important impact on greenhouse gas emissions.


Academics on sabbatical leave are usually 'taking stock' of their previous research, thinking about writing a book or starting new projects. I have chosen a rather indirect path to enlightment: to spend my sabbatical in a hedge fund trading options and forecasting volatility. Hopefully, this request of the Editor-in-Chief of Quantitative Finance for writing a 'general article on volatility' will be an opportunity to reflect a bit on the interrelation of option pricing theory and quantitative trading strategies as I see them today. First, the usual disclaimer: a state-of-the-art survey paper on volatility trading is impossible to write, at least for me. There is simply too much material. For this reason, I will limit this paper to a few topics that I am familiar with, namely where pricing theory and trading interact. We are at a turning point in pricing theory. On the theoretical side of things, the input of mathematicians and physicists on the field has been tremendous. Confluent hypergeometric functions, integro-differential equations, multi-factor models — just to mention a few examples — have been applied to pricing options and many papers have been published in quantitative finance journals such as this one. If a researcher even thinks about a probability distribution as an alternative to the Black–Scholes model, chances are that this distribution has already been tested (usually by a graduate student or a Wall Street quant), a paper has been written and it has been put to work somewhere. So, is option-pricing theory dead? I believe that the answer is 'no', but that we need to broaden our horizons. First point: until now, option-pricing theory has worked almost exclusively on improving the 'pricing kernel'. It has not considered other very important elements that go into the price of an option. I am referring to the effects of news about the underlying asset that will be released during the lifetime of the option at known dates. To generate profitable trades, option traders have to reconcile stylized facts about the movement of the underlying asset and the history of implied volatilities with the current price of an option and determine whether it is fairly valued. This judgment will necessarily take into account the fact that there are earnings announcements, releases of macro-economic statistics, ex-dividend dates, takeover proceedings and court judgments, the results of clinical trials (in the case of biotechnology and pharmaceutical stocks) or other idiosyncratic news that will be released over the life of the option. Option pricing theory has proposed very little in terms of handling these very real issues. For theorists, this is a controversial point: the efficient markets dogma assures us that all news is 'priced in' so we need not worry. But is this really the case? I don't think so. The impact of a theory improved in this direction would be great. Second point: very recent structural developments in options markets may lead to exciting new trading techniques and improved the way in which we view and price listed options in aggregate. This major development is the advent of electronic trading of equity options as a primary way of trading in the U:S: markets ('Direct Market Access'). To some extent, parallel developments are taking place in Europe. Electronic access allows traders to view the market as composed of multiple exchanges — each with its bid-ask spread and depth — and to trade options on several underlying assets across different markets systematically. This leads naturally to portfolio trading of options. An option pricing theory that can handle in a practical way multiple underlying stocks has yet to emerge.


A detailed treatment of the conformations of a one‐dimensional polymer molecule adsorbed to a surface is given. The average number of contacts of the chain with the surface, the end‐to‐end length, and the distribution of segments ρ(z) with respect to distance z from the surface are computed as functions of the chain length (N) of the polymer and the attractive energy of the surface. Both theoretical and Monte Carlo calculations are used. A transition is found at an attractive energy of kT ln 2. For attractive energies less than this value, the average number of contacts of the chain with the surface approaches a finite value as N approaches infinity, while the end‐to‐end length vaires as N½. However, above the transition the number of contacts is proportional to N and the end‐to‐end length is independent of N. The distribution of segments ρ(z) also shows a marked change as we go through the transition. The one‐dimensional model is shown to correspond to the projection of a three‐dimensional model on the d...


4th European Advanced Accelerators Concepts. More than 250 scientists from all over the world gathered from Sep 15 – 21 at the 4th European Advanced Accelerator Concept Workshop (EAAC) on the Island of Elba in Italy. Specialists from accelerator physics, RF technology, plasma physics, instrumentation and the laser field discussed ideas and directions towards a new generation of ultra compact and cost effective accelerators with ground-breaking applications in science, medicine and industry. The EAAC was founded by the European Network for Novel Accelerators (EuroNNAc) in 2013 and has grown in its fourth edition into a meeting with world-wide visibility, rapidly catching up with the long tradition of the Advanced Accelerator Concepts workshop (AAC) in the US. At the EAAC senior scientists from various specialties mix with junior experts and a large community of young students, attracted by the promise and success of compact particle accelerators. In 2019 about 50 PhD students presented their work at the EAAC. Besides the reports on scientific achievements the large diversity in gender, age distribution and nationalities made the EAAC 2019 a special event and a great success for the accelerator field. Group photo of the EAAC 2019 attendants is present in this pdf. Committees List of Workshop Organizing Committee, Programme Committee, International Advisory Committee, Local Organizing Committee and Proceedings Editors are available in this pdf.


Summary The economical desideratum in the cow farms is being represented on one hand, by obtaining a high production of milk with a high content of proteins, and on the other hand, by the achievement of one calf a year. For this to happen there has to be a bond between the axis hypothalamus – hypophysis – uterus – ovaries. The progresses registered in the domain of breeding cows regarding the production and the quality of milk, involves the necessity of doing some ample investigations of the intermediary metabolism of nursing animals, with the purpose of a rentable lead for the fodder's regime. Through this work we want to be able to establish the condition of health for cows in peripartal period. The research was made on 20 (HF) cows, with over 8000 liters of milk production in the private area. In the conclusion, the most important factors for maintaining a physiological condition are being represented by a proper feeding during mammary repose. Key words: energy, protein, mineral profile, dairy cows, peripartal period


This paperp shows that Dykstra's procedure for finding the I-projection onto the intersection of closed convex sets holds in general. It does this by first showing that each of the I-projections onto individual convex sets defined in Dykstra's iterative procedure exists and that no condition such as imposed by Dykstra is required to prove the convergence of the iterative procedure to a unique I-projection


—This paper presents the central concepts for a microservices-based distribution of event stream processing pipelines as they are part of our situation-aware event stream processing system. For this, we outline changes to our specification language for a clear separation of the stream processing specification from the actual stream processing engine. Based on this separation, we then discuss our mapping approach for the assignment of the pipelines to stream processing nodes.


DEVELOPING AKIDAH AKHLAK TEACHING MATERIAL AT MADRASAH IBTIDAIYAH. Teacher has a strategic role in the learning process, can be said that to realize the learning success is teacher responsibility. The learning successit was not yet enough if only measured by how many students who can pass and get a good score, especially in teaching AkidahAkhlakstudent must actualize the Islamic values in their real life. This article tried togive the impression how provide the purpose of the AkidahAkhlaklearning process, by developing AkidahAkhlakteaching materials at the elementary level, without deny the principlesthat must be fulfilled in developing teaching materials. k eywords: Teaching Materials, Akidahakhlak, Madrasah


The City of London's draft local plan, published in late 1984, sets out the corporation's planning strategy for the next 10–15 years for the City's environment and its working, living and recreational life. It has far‐reaching implications for offices.


Abstract A rigorous statistical method is established to compute the rate constants of the bimolecular decomposition of redox catalysts used to initiate polymer chains. Results obtained for the systems styrene-dimethylaniline-benzoyl peroxide and acrylamide-thio-glycollic acid-potassium bromate compare favorably with those reported by other workers. The merits of this error-in-variable technique, which outperforms conventional nonlinear least-square analysis and the dead-end polymerization method, are discussed.


To assess the effectiveness of music therapy on
pain perception and anxiety level in first stage of labour in labour ward at
Government Rajaji Hospital, Madurai.
Objectives:- To assess the level of pain and anxiety among primi gravid
mother in first stage of labour for the experimental group and control group. To assess
the effectiveness of music therapy in first stage of labour in terms of pain reduction
and anxiety in the experimental group.
Materials and methods:- The experimental design adopted for my study is
pretest and posttest design. The sample technique using in this study simple random
sample. The conceptual framework adopted for my study modified Roy Adaptation
Theory. This technique is used in labour ward at Government Rajaji Hospital,
Madurai. Music therapy was given to reduce the level of labour pain and anxiety. The
pre and post assessment level of labour pain and anxiety was obtained using a
modified Combined Numerical Categorical Pain Intensity Scale and modified state
trait anxiety scale. The data were analyzed by inferential and descriptive statistical
methods.
Result:- In posttest, experiment mothers are having 46.83 anxiety score and
control group mothers are having 73.80 anxiety score. 't' test p = 0.001. So
statistically significant in control group't' test p = 0.001. In posttest in experimental
mother having 4.03 pain score, in control group 6.90. The difference is 2.87 t = 11.98.
So statistically significant.
Conclusion:- The mean posttest level of pain and anxiety among primi gravid
mothers in experimental group was lower than the mean posttest level in control
group. So music therapy is effective in reduction of pain perception and anxiety level
among primi gravida mother


NMR spectroscopy is ideal for studying weak interactions (formation enthalpy {le}20 kcal/mol) in solution. The metallocene bis(pentamethylcyclopentadienyl)ytterbium, Cp*{sub 2}Yb, is ideal for this purpose. cis-P{sub 2}PtH{sub 2}complexes (P = phosphine) were used to produce slow-exchange Cp*{sub 2}YbL adducts for NMR study. Reversible formation of (P{sub 2}PtH){sub 2} complexes from cis-P{sub 2}PtH{sub 2} complexes were also studied, followed by interactions of Cp*{sub 2}Yb with phosphines, R{sub 3}PX complexes. A NMR study was done on the interactions of Cp*{sub 2}Yb with H{sub 2}, CH{sub 4}, Xe, CO, silanes, stannanes, C{sub 6}H{sub 6}, and toluene.


Edward mangoes having a selected range of diameters and in green-ripe stage were submitted to controlled storage. Green-ripe fruits with their greater diameter 3 in or more ripened into good quality fruits when stored at 70° F (21 o C) and 85-90% relative humidity.


Wall slip occurs under large amplitude oscillation shear (LAOS) for yield stress fluids. In this work, we investigated how the boundary conditions affect the nonlinear behavior under LAOS and proposed a simple methodology based on the geometric average of Lissajous curves to study the dynamic wall slip behavior under oscillatory shear. The results show that the stress-mean strain curve is a good candidate to define material's functions since it is almost not influenced by the wall slip effect. Meanwhile, the stress-mean strain rate curves from smooth plates and rough plates can be used to determine the wall slip velocity. It is found that the intercycle maximum slip strain rate follows the generalized Navier's law, while the intracycle slip behavior can be well described by a Maxwell-like dynamic slip model, which helps to determine the slip relaxation time. It is also found that the slip Deborah number is independent of the angular frequency and is a monotonically decreasing function of the reduced stres...


The iterative method was used for studying the approximation problem of solutions for k-accretive operator equations in general Banach spaces.A general theorem was established about the Ishikawa iterative sequence with errors which strongly convergence to solutions and the stability of the iterative process was discussed.Relevant results of reference literature were improved and extended,and the more general results were obtained by using the k-subaccretive operator to replace the subaccretive operator.


There has been increasing interest in complementary health practices among patients, popular media, and even institutional health care providers. However, there is still surprisingly little information on the use of alternative medicine by patients undergoing treatment for prostate carcinoma.


Perceptual and acoustic analyses were used to investigate the stress patterns of Chinese disyllabic constituents with identical pronunciation and different morph-syntactic structures.Tests demonstrate that the stress patterns in standard Chinese(SC) are "Strong-Weak" when the final syllable is a neutral tone and that this stress pattern can be used as the cue to discriminate meanings of the disyllabic constitutes.However,due to the final lengthening effect,disyllabic constituents without neutral tones were inclined to be the "Weak-Strong" pattern,which exhibits no corresponding relation with the morph-syntactic structures.


This research intends to identify the nature of the relations between the European Union and the Andean Community, which was known as the Andean Pact (Pacto ...


Seven patients with widespread bony metastases, with and without hypercalcaemia were given porcine or salmon calcitonin in an attempt to reduce that rate of progression of their disease, possibly to reduce pain and to accelerate healing during the course of other endocrine therapy. The latter included the administration of phosphate, steroids, androgens or oestrogens and hypophysectomy. Calcitonin effects were seen to be enhanced by simultaneous administration of phosphate and possibly antagonised by oestrogens. The metabolic changes that did occur, suggested that the rate of healing of metastatic bone disease was increased and the mechanisms of these changes are discussed. Metastatic malignant cells in bone may induce changes there in a variety of ways: (a) By direct invasion of the bone marrow with lysis of bone elements by the combined effects of osteolysis, "pressure", ischaemia or hyperaemia (Shivas et al. 1963; Gorenham 8c Test 1964). The effects are similar to those of fracturepain, oedema and deformity and at the microscopic level, a mixture of in¬ flammatory and reparatory changes (Galasko 1972). Downloaded from Bioscientifica.com at 10/17/2018 09:48:57PM via free access (b) By the hormonal stimulation of the normal bone cells to increase the rate of bone destruction. The clinical presentation is one of bone pain, although fracture may be a late presenting feature. Histologically, the picture is similar to that of hyperparathyroidism: an increase in osteoclastic activity, multiple résorption cavities not lined by malignant cells and an excess of woven bone (Galasko 1972). Increased levels of immunocreative parathyroid hormone have been found in patients in this group (Tashjian et al. 1964; Sherwood et al. 1967). Studies of the urinary excretion of calcium in patients with carcinoma of the breast when compared with the plasma calcium concentration, suggested increased tubular résorption of calcium, a finding typical of hyperparathyroid¬ ism (Nordin 8c Peacock 1969). Studies with 4;Ca in these patients suggested an overall increase in bone turnover in keeping with a diffuse hormonal change (Parsons et al. 1970). (c) A third possible mechanism is inhibition of the action of Vitamin D by the tumour, by production of a local deficiency of phosphate giving rise on a minor scale to what is sometimes mistaken for Vitamin D resistant rickets. This mechanism may explain the predominant osteoid seams seen close to some bone marrow deposits (Follis 1950). (d) A rare mechanism postulated by Gordon et al. (1967), is the production by some breast carcinomas of an osteolytic sterol, resulting in the developments of bone lysis without the presence of métastases Stephen Paget's disease of bone (Gordon et al. 1971). On the basis of all these mechanisms it would seem likely that calcitonin can interfere with some of the lytic processes whether or not there is hypercal¬ caemia. Bijvoet et al. (1968) previously considered the indication for calcitonin therapy in the majority of treated patients (Foster et al. l9&Qa,b; Milhaud Sc Job 1966; Pak 8c Wills 1968; Foster 1968; Kammerman 8c Caufield 1970). The simultaneous administration of phosphate salts steroid hormones and other therapy was to some extent unavoidable, since several patients were admitted to the trial with their therapy already of proven benefit. The treatment regime was simplified by stopping radiotherapy and most other therapy for some time before commencing calcitonin therapy. It was not expected that calcitonin would be inhibited by any of the therapies in use. although phosphate ad¬ ministration had been shown to enhance the action of calcitonin in mammals (Hirsh 1968).


to policy, have generally concerned themselves either with an undifferentiated group of roll calls or with roll calls in a single policy area. The question arises whether legislative voting blocs, as derived from a general sample of policy roll calls, are identically constituted when specific subsample policy areas are considered separately. Investigators have analyzed voting relationships within pairs of legislators, judges, nations, and other decison-making units.' These methods, derived from the early work of Rice2 and Beyle,3 can be applied to the task of drawing bloc-maps portraying the vote agreement location of legislators relative to their colleagues. What is proposed here is to employ voting agreement indices of pairs of legislators to investigate variations in the configurations of voting blocs on a variety of policy areas at issue in the same legislative session.4 The study will begin by establishing voting blocs based on all roll calls chosen for analysis, using the voting agreement indices of each legislative pair. Following this, the study will analyze variations that may occur in the blocs as various issue areas are extracted from the total body of roll calls. The study will thus allow conclusions as to the policy orientations of legislators and the stability of blocs across several policy areas.


In this paper, we present systematically analysis on the smallest eigenvalue of matrices associated with completely even functions (mod r). We obtain several theorems on the asymptotic behavior of the smallest eigenvalue of matrices associated with completely even functions (mod r). In particular, we get information on the asymptotic behavior of the smallest eigenvalue of the famous Smith matrices. Finally some examples are given to demonstrate the main results.


One of the most active fields in semiconductor research is the development of electronic de‐ vices capable of function at high powder and high frequency levels, high temperatures, and caustic circumstances. This surge of activity is strongly driven by the urgent desire for re‐ placing the current Siand GaAs-based electronics because they are unable to operate prop‐ erly under harsh environmental conditions. As a promising substitute, the wide-band-gap semiconductor, silicon carbide (SiC), has captured considerable attention recently due to its excellent intrinsic properties, which involve large breakdown electric field, high electron sat‐ uration drift velocity, strong hardness, and good thermal conductivity. On the other hand, current significant improvements in the epitaxial and bulk crystal growth of SiC have paved the way for fabricating its electronic devices, which stimulates further interest in developing device processing techniques so as to take full advantage of its superior inherent properties.


Cryptojacking is currently being exploited by cyber-criminals. This form of malware runs in the computers of victims without their consent. It often infects browsers and does CPU-intensive computations to mine cryptocurrencies on behalf of the cyber-criminal, which takes the profits without paying for the resources consumed. Such attacks degrade computer performance and potentially reduce the hardware lifetime. We introduce a new cryptojacking detection mechanism based on monitoring the CPU usage of the visited web pages. This may look like an unreliable way to detect mining malware since many web sites are heavy computationally and that malware often throttles CPU usage. However, by combining a set of CPU monitoring features and using machine learning, we manage to obtain metrics like precision and recall close to 1.


Sorption and ion exchange have been widely employed by the nuclear industry to decontaminate aqueous waste streams. Standard formulations of adsorbents are used world-wide to process radioactive liquid wastes. As discharge limits are lowered by regulatory authorities, it is more challenging for operators to comply with the governing principles of ALARP (as low as reasonably practicable) and BATNEEC (best available technology not entailing excessive cost).


An overview of digital predistortion techniques for microwave power amplifier linearization is here presented. Different predistortion approaches are considered, and both static and dynamic (memory effects) behavioral models are presented. Special focus is done to the most suitable solutions for facing the new challenge to linearize high-bandwidth amplifiers, as demands most of the new telecommunications standards and emergent technologies related with cognitive radio.


The ratios of inclusive electron scattering cross sections of He-4, C-12, and Fe-56 to He-3 have been measured for the first time. It is shown that these ratios are independent of x(B) at Q(2)>1.4 GeV2 for x(B)>1.5, where the inclusive cross section depends primarily on the high momentum components of the nuclear wave function. The observed scaling shows that the momentum distributions at high-momenta have the same shape for all nuclei and differ only by a scale factor. The observed onset of the scaling at Q(2)>1.4 GeV2 and x(B)>1.5 is consistent with the kinematical expectation that two-nucleon short range correlations (SRC) dominate the nuclear wave function at p(m)greater than or similar to300 MeV/c. The values of these ratios in the scaling region can be related to the relative probabilities of SRC in nuclei with Agreater than or equal to3. Our data, combined with calculations and other measurements of the He-3/deuterium ratio, demonstrate that for nuclei with Agreater than or equal to12 these probabilities are 4.9-5.9 times larger than in deuterium, while for He-4 it is larger by a factor of about 3.8.


SUMMARY The idea that the addition of compound feed to grass at ensilage can result in adequate preservation of the crop without the need for an acid additive, and that less compound feed would then need to be given when the silage is subsequently fed, was tested with dairy cows. Two diets were compared: (1) a conventional grass silage, to which acid had been added at the time of ensiling, plus concentrates supplied at the time of feeding, and (2) grass silage, to which a compound feed had been added at the time of ensiling, plus a lower rate of concentrates. Each diet was fed to 12 lactating cows for 82 days. The total intake of dry matter was 17·3 kg per cow per day on diet 1 and 18·3 kg on diet 2. Daily milk yields per cow were 24·5 and 26·1 kg, respectively, with similar milk composition. The estimated diet costs per kg of milk were 9·3 p on (1) and 8·3 p on (2). It is concluded that the addition of compound feed to grass at ensilage is worth considering on dairy farms as an alternative to conventional grass silage, but that a more comprehensive study is needed.


Excerpt The primary function of the lungs is to transmit to the arterial blood coursing through them an adequate supply of oxygen from the inhaled atmospheric air. During expiration carbon dioxide ...


We examine the role of rituals in institutional maintenance. Through an in-depth, qualitative study of formal dining at the University of Cambridge, we explore how the performance of these rituals contributes to the maintenance of the British class system. We find that rituals are important for institutional maintenance because they have a powerful bearing on participants beyond the confines of the rituals themselves. Our analysis also suggests that institutions are refracted through context and individual experience at a micro level, and indicates a more fragmented and less strategic conception of institutional maintenance than is portrayed in recent work.


The method of intermediate alloy-vacuum distil lation for preparing high-purity dysprosium metal has been studied The influences of raw material purity and impurity removal by vacuum distillation were discussed.The total content of main non-RE metal impurities in the high-purified dysprosium metal prepared is only 705μg/g,and the content of C,N and O is 32μg/g,2μg/g and 50μg/g,respectively.


A directed graph, called an M-graph, is attached to every melody. Our chief concern in this paper is to investigate (1) how the positivity of the slope of the M-graph is related to singability of the melody, (2) when the M-graph has a symmetry, and (3) how we can detect a similarity between two melodies. For the third theme, we introduce the notion of transposed discrete Frechet distance, and show its relevance in the study of similarity detection among an arbitrary set of melodies.


The objective of this study was to determine the effect of temperature and artificial saliva solution on the tensile force of orthodontic power chains. We studied 56 orthodontic power chain specimens (Ormco, Orange, CA, USA), the closed type, that were stretched at 100% of the initial length (40 mm). Each group was stretched on an acrylic plate immersed in artificial saliva solution and Aqua Dest for 210 minutes. The tensile force was measured using a Correx meter force gauge with units of grams-force (gf) at the initial and final immersion. The temperatures used in this study were 4°C obtained from the refrigerator, 23°C from storage at room temperature, 37°C from storage in an incubator, and 55°C from heating with a hot plate. Our results showed a significantly decreased tensile force (P < 0.05) at various immersion temperatures. The effects of the immersion medium (artificial saliva solution and Aquadest) resulted in a significant decline in tensile force at 23°C (P < 0.05), but the results at 4°C, 37°C, and 55°C were not significantly different.


Summary This study investigated the effects of a personality variable (hostility) and an experimental variable (observation of models) on Rorschach performance and interview behavior. Females differing on a measure of hostility observed either a high, low, or non-hostile model's Rorschach performance or observed no model prior to their own Rorschach testing. Ss also engaged in verbal self-description and daydream rating tasks. Results indicated that observation (1) facilitated the emission of hostile Rorschach response content for low but not for high hostile Ss and (2) promoted more Rorschach response productivity and diversity. Intercorrelations among 13 indices of hostility revealed that questionnaire and interview self-description measures were interrelated, but were not consistently related to the projective measures.


A two level model is considered to describe the dynamics of a biological system undergoing cyclic oscillations from one state to another separated by an energy quantum interval. This is typically met in enzyme activated reactions, involving the ADP-ATP cycle. General results can be obtained analytically, the dynamics of the system being investigated from an energetic point of view. Numerical solutions show how an enzymatic system can be driven across different regimes where cooperation (allostericity) and oscillations appears. The model can be extended to the case of an external energy supply in the form of electromagnetic radiation, providing clues for a physical understanding of nonthermal laser interaction with biosystems.


Current studies of the manner in which elastic waves are generated by buried explosions, such as the moment tensor approach, require high-quality broadband ground motion data. In order to obtain such data at distances of a few kilometers from the source, a method or recording the ground motion with force-balance accelerometers and triggered event recorders has been developed and tested. The two NTS events EMMENTHAL and FARM were recorded in the distance range 0.5 - 10 km. A few problems with the method were identified and corrected, and it now appears to be an excellent method of acquiring data from NTS explosions at small distances. The data recorded from EMMENTHAL and FARM illustrate quite clearly a phenomenon that has been observed on records of previous events but still not very well understood. This is the matter of significant energy on the transverse component of motion, some of it arriving at the time of the P wave. This appears to be an important problem worthy of further study. Its resolution could affect the interpretation of the phases that appear on the radial and vertical components of motion.


Introduction:
 Acute myocardial infarction (AMI) during pregnancy is a rare but fatal complication. Recent trends in incidence of pregnancy-related AMI and associated outcomes are unclear.

 Methods:
 Nationwide inpatient sample (NIS) database was utilized for years 2005-2014. International classification of disease-Ninth revision (ICD-9) was used to identify pregnancy-related (antepartum as well as postpartum) admissions and acute myocardial infarction (AMI). The primary outcome was incidence and trend of AMI related to pregnancy during the study period. Secondary outcomes were trends in mortality and resource utilization. P-values for trends were generated by Cochrane-Armitage test for categorical variables and simple linear regression for continuous variables.

 Results:
 We identified a total of 43,437,621 pregnancy-related hospitalization and 3,786 cases of AMI (86% antepartum and 14% post-partum) were noted during the study period. The incidence of AMI during the study period was 8.7 per 100,000 pregnancies with an overall increase in incidence during study period (relative increase of 18.9%, p <0.001) and concomitant decrease in mortality (relative decrease of 40.05%, p <0.001), cost of care (relative decrease of 8.70%, p<0.001) and length of stay (relative decrease of 13.53%, p<0.001).

 Conclusions:
 Incidence of AMI during the period is on the rise in recent years with concomitant improvement in mortality and resource utilization. This reflects improved diagnostic capability and a better understanding of non-atherosclerotic mechanisms of AMI during pregnancy such as spontaneous coronary artery dissection, coronary spasm, and coronary thrombus.


It is proposed to use the Shuttle (OFT experiments) or eventually Spacelab to study, in the absence of gravity the low velocity accretion and the bulk properties of icy conglomerates simulating cometary material and their sedimentation and bulk properties in very small acceleration fields. Their behavior when exposed to the direct solar flux is also under consideration.


ation Theme" as one of the primary motivators for becoming a teacher (1975 29-30). Simply put, people who liked school as students often decide to work in schools as adults. It's possible that one of the motivators for staying in the professiongoing the distance-may be the extent that continuation is realized. Sadly, the crush of daily responsibilities can make reflection upon practice, motivation, and even job satisfaction impossible: we forget the reasons we became teachers in the first place and wonder if we remain in the classroom


The invention provides a GOA (Gate-Driver-on-Array) circuit for reducing feed-through voltage. An eleventh thin film transistor (T11) and a first resistor (R1) connected with the eleventh thin film transistor (T11) in series are additionally arranged in a drop-down output unit (400), in the output process of the GOA circuit, the eleventh thin film transistor (T11) is switched on through output control signals (CKF) arranged additionally, by means of the voltage dividing function of the first resistor (R1), a signal waveform output by the output end (G(n)) generates one more falling edge, namely the signal waveform output by the output end (G(n)) has two falling edges, and voltage difference before and after closing a TFT grid in pixels can be reduced, so that feed-through voltage is reduced, and the display uniformity of a liquid crystal display panel is promoted.


Pariser–Parr–Pople-type SCF MO and semiempirical magnetic-susceptibility calculations show that trinaphtho[abc,ghi,mno]- and two kinds of triazuleno[abc,ghi,mno][18]annulenes have large diamagnetic susceptibilities and aromatic-islands structures in which three naphthalenes or three azulenes are linked by three olefinic bridges, whereas tripentaleno[abc,ghi,mno]- and triheptaleno[abc,ghi,mno][18]annulenes have small diamagnetic susceptibilities and polyolefine structures where bond alternations are distributed all over their molecular planes.


When nucleotide hydrolysis is prevented, agonists of the P2Y12 receptor enhance the proliferation of C6 glioma cells by RhoA‐dependent, protein kinase C (PKC)‐dependent activation of the extracellular signal‐regulated kinase (ERK) pathway [Claes P, Grobben B, Van Kolen K, Roymans D & Slegers H (2001) Br J Pharmacol134, 402–408; Grobben B, Claes P, Van Kolen K, Roymans D, Fransen P, Sys SU & Slegers H (2001) J Neurochem78, 1325–1338]. In this study, we show that ERK1/2 phosphorylation was not affected by transfection of the cells with the Gβγ‐subunit‐scavenging adrenergic receptor kinase peptide [βARK1‐(495–689)] or with Rap1GAPII, indicating that P2Y12 receptor stimulation enhances ERK1/2 phosphorylation by Giα subunit‐mediated signaling independently of Rap1 activation. Inhibition of the RhoA downstream effector Rho‐associated coiled‐coil‐containing kinase (ROCK) with Y‐27632 did not affect the P2Y12 receptor‐induced increase in ERK1/2 phosphorylation but abrogated the mitogenic response. Involvement of growth factor receptor transactivation in the signaling towards ERK phosphorylation could be ruled out by the lack of an effect of PP2, AG1024, AG1296 or SU1498, inhibitors of Src, insulin‐like growth factor receptor, platelet‐derived growth factor receptor and vascular endothelial growth factor receptor kinase activity, respectively. Experiments with bisindolylmaleimide I and IX indicated the requirement of PKC activity. Classical and novel PKC isoforms could be excluded by treatment of the cells with Gö6976 and calphostin C, whereas addition of a myristoylated PKCζ pseudosubstrate inhibitor completely abolished P2Y12 receptor‐induced ERK1/2 activation. Moreover, coimmunoprecipitation experiments revealed PKCζ/Raf1 and PKCζ/ERK association, indicating the involvement of PKCζ. From the data presented, we can conclude that the P2Y12 receptor enhances cell proliferation by a Giα‐dependent, RhoA‐dependent PKCζ/Raf1/MEK/ERK pathway that requires activation of ROCK, which is not involved in ERK1/2 signaling.


Surface and sub-surface fire in municipal solid waste landfills (including dumpsites) is a complex and intricate phenomenon, whose frequency is expected to increase due to climate change. Partial or incomplete combustion of landfill waste at low temperatures during fires leads to generation of toxic compounds, including hydrocarbons, particulate matter and hazardous gases, which contaminate the surrounding geoenvironment and ultimately pose severe health hazards to living entities. Under these circumstances, it is the need of the hour to understand the (i) occurrence mechanisms of landfill fires, (ii) waste properties and operational conditions that may favour landfill fires and (iii) strengths and limitations of the available detection techniques in order to provide recommendations to detect such incidences at an early stage and plan emergency measures. Hence, the present review article critically assimilates the literature on landfill fires and discusses the (a) conditions under which the initiation and sustenance of landfill fires take place, (b) ecotoxicological (geoenvironmental) hazards of landfill fires, both in short- and long-term and (c) detection techniques for an early warning system. Finally, a discussion on the coupled multi-physics interactions undergoing in the waste matrix during landfill fires is presented in this manuscript, which is crucial to mastering this subject.


We have considered the effect of the reduction of the solar neutrino flux on earth due to the deflection of the charged neutrino by the magnetic field of the solar convective zone. The antisymmetry of this magnetic field about the plane of the solar equator induces the anisotropy of the solar neutrino flux thus creating the deficit of the neutrino flux on the earth. The deficit has been estimated in terms of solar and neutrino parameters and the condition of a 50 % deficit has been obtained: Q ν gradH ≥ 10 − 18 eG/cm where Q ν is the neutrino electric charge, gradH is the gradient of the solar toroidal magnetic field, e is the electron charge. Some attractive experimental consequences of this scenario are qualitatively discussed.


The study explores the image positioning of Wushu's"going out". It holds that the rapid development of science and technology makes people more rely on their senses to obtain information,w hich influences the people's life and aesthetics as w ell as their recognition to Wushu 's image. When Wushu 's image is of importance to Wushu's existence and development,the image of Wushu 's "going out " is determined by Wushu practitioners and their thinking,as human is the carrier of Wushu communication. M eanw hile the subject of school Wushu,mass Wushu and competition Wushu communication is also human being. Therefore,w e should cope w ith the relationship betw een Wushu standardization and school Wushu, mass Wushu and tradition Wushu correctly; shape the image of Wushu 's "going out"and advance the Wushu's international communication.


Aim. To assess the effect of immunosuppressive cyclophosphamide therapy and its regimens on the rate of progression of chronic kidney disease in mesangioproliferative glomerulonephritis.
Methods. 72 patients with mesangioproliferative glomerulonephritis and indications for immunosuppressive therapy with disease activation were included in the comparative analysis: 56 patients received cyclophosphan in conventional doses (26 patients with daily or every other day, 30 patients with in pulse mode 1 time per month), and 16 patients did not receive cyclophosphan. Duration of the disease before observation ranged from 0 to 33.58 years, a median follow-up was 6.00 (interquartile range 1.6313.17) years, and after observation from 0 to 5 years with the median follow-up was 2.00 (1.003.50) years. The examination included nephrobiopsia with a morphological diagnosis, activity index/sclerosis, and glomerulonephritis progression rate for decreased glomerular filtration rate (ml/min/1.73 m per year).
Results. The progression rate of chronic kidney disease was higher in the group of patients not receiving immunosuppressive therapy, 5.57 (3.277.95) ml/min/1.73 m2 per year compared with of the treated patients group, 3.05 (2.046.78) ml/min/1.73 m2 per year (p=0.040). There were no differences in the rate of decrease in glomerular filtration rate between groups depending on the treatment regimen: 4.86 (2.126.77) ml/min/1.73 m2 per year with regular and 3.67 (2.04 6.91) ml/min/1.73 m2 per year with a pulse mode (p=0.720). The rate of glomerulonephritis also did not differ significantly: 1.0 (1.02.0) and 2.0 (1.02.0) relapses over 5 years, respectively (p=0.691) in both treatment regimens.
Conclusion. The treatment of patients with mesangioproliferative glomerulonephritis with cyclophosphane, in combination with prednisone or without it, regardless of the treatment regimen induces a slowdown in the progression of chronic kidney disease, improving the long-term prognosis and without affecting the frequency of relapses of the disease.


It has recently been proposed that alpha 2 adrenergic receptor is also located at the vascular endothelial cells and the stimulation of thereceptor leads to the release of endothelium derived relaxing factor(EDRF).Therefore,the removal of the endothelium markedly enhanced the vasoconstrictor re- spouse to norepinephrine(NE)and other alpha-agonists.However,the influence of the endothelium on the vasoconstrictor response to endogenous NE from adrenergic nerves remains unclear.In this work,the influence of methylene blue(MB),hemoglobin(Hb)and acetylcholine(ACh)on the vasoconstrictor response to electrical stimulation of the spinal sympathetic nerve in the perfused hind limb of the pithed rats has been observed.The spinal stimulation induced the frequency-dependent increase of the hind limb perfused pressure(HPP).During the infusion of MB(10μmol·L-1)and Hb(10μmol·L-1),the special inhibitors of EDRF,HPP to spinal stimulation at 16 Hz for 20 s were significantly enhanced,whereas the responses at 1 and 4 Hz were unaffected.ACh(1μmol·L-1)markedly inhibited the response to spinal stimulation at 1,4 and 16 Hz.It is concluded thatEDRF inhibits the vascular response to the sympathetic stimulation and released NE by high frequency stimulation from adrenergic nerve terminal,located almost exclusively at adventitial-medial border,would diffuse through smooth muscle cells prior to reaching and stimulating alpha-2 receptor at the endothelial cells.However,NE level by low frequency stimulation is so low that it would not reach the endothelium.As a physiological role,the endothelium will modulate the vascular response to severe stimulation by releasing EDRF.


The invention relates to removing ring down effects from sonic waveforms. An illustrative acoustic range finding method including deploying a tool downhole, transmitting a first acoustic waveform with a transmitting acoustic transducer of the tool, receiving a second acoustic waveform with a receiving acoustic transducer of the tool, removing a deterministic waveform from the second acoustic waveform to obtain an echo waveform, and deriving a measurement from said echo waveform.


ABSTRACT It has become a conventional wisdom in strategic studies that the development and use of cyber weapons should be kept secret, as the effectiveness of these tools is dependent on opponents being unaware of a particular cyber weapon's characteristics. Why, then, has the US military repeatedly publicized its cyber operations against ISIS in Syria and Iraq? Why reveal what is supposedly better conducted in the dark? In this essay, we provide four answers to this puzzle. We argue that the Pentagon aims to (1) legitimize major investments in the cyber domain to a domestic audience, (2) undermine the enemy's trust in his own IT-infrastructure, and command and control systems, (3) signal "cyber strength" to third parties, and (4) establish norms regarding how to use cyber weapons in accordance with International Humanitarian Law.


In the present paper, I suggest a modification to some aspects of Ingarden's analyses of the sound-synchronized filmic work of art. The argument progresses through two stages: (1) I clarify Ingarden's claim that the work of art is a stratified formation in which the various aspects present objectivities; (2) I elucidate and critically assess Ingarden's suggestion that the filmic work of art is a borderline case in respect to other types of works of art—paintings and literary works. Here, I identify a problem with Ingarden's claims about the function of sound in the concretized filmic work's presentation of its fictive world. Ingarden identifies the presented universe of the filmic work of art as a habitus of reality, but Ingarden seems oddly conflicted with respect to his notion of habitus. I argue that this stems from Ingarden's conceptualization of the filmic work of art as primarily composed of the stratum of represented "visible aspects" in both the cases of the silent film and the sound-synchronized film, and his restriction of the role of phonetic content in the latter. I suggest that were we to reconceptualise the role of aurally presented phonetic content in the concretized sound-synchronized film, we could better understand how film has the seeming magical capacity to transfix us.


BACKGROUND
The utility of neuropsychology in the treatment and evaluation of neuropsychological disorders and neurodegenerative diseases is supported by scientific study. As a discipline, neuropsychology's value and efficacy when applied to the dementia spectrum are rooted in its inherent adaptability as a practical, cost-effective, and scientifically based resource for differential diagnosis, treatment planning, and forensic decision making.

OBJECTIVES
This article provides a framework for conceptualizing dementia as a spectrum of disorders and outlines a rationale for preferential reliance upon neuropsychological tenants. The function of neuropsychology in differential diagnosis, clinical management, integrative care, and forensic applications is delineated for use as a contemporary interdisciplinary reference.

METHODOLOGY
An overview of the literature on dementia as a spectrum of disorders has been integrated with the science and practice of neuropsychology.

CONCLUSIONS
The utility of neuropsychology emanates from its focus on brain functioning and the discipline's appreciation for the relationship between brain functioning on cognition, mental state, and behavior. Early and routine referral for neuropsychological assessment allows for the objective determination of normal versus abnormal neurocognitive functioning, provides a baseline for serial reassessment, and leads to the more rapid deployment of effective treatments. Beyond the hospital and clinic, neuropsychological expertise is increasingly sought after as integral to the legal system when decisions regarding eligibility for long term care and questions about capacity require objective and reliable measurement.


A new approach to metalware minimal remaining life estimation using metalware test results with acoustic emission method and materials test results with fracture strength criterion detection in laboratory environment is suggested.


Rice starches from low amylose (Pathum Thani 1), medium amylose (RD 7) and high amylose (Leuang 11) varieties prepared from dry- and wet-milling processes were investigated. Dry-milled rice starches contained significantly (p<0.05) higher amounts of damaged starch than wet-milled rice starches in all rice varieties. The scanning electron micrographs (SEM) of starch granules confirmed that damaged starches occurred from the dry-milling process more than from the wet-milling process. The enthalpy required to gelatinize dry-milled rice starches (8.11-9.53 J/g) from all rice varieties was significantly (p<0.05) lower than those of wet-milled rice starches (9.24-12.48 J/g). The peak viscosity (257.75353.80 RVU) and final viscosity (248.64-391.00 RVU) of dry-milled rice starches measured by Rapid Visco Analyser (RVA) were significantly (p<0.05) lower than those of wet-milled rice starches. Rice starch molecular weight distributions obtained by size-exclusion chromatography with RI and multiangle laser light scattering detection (SEC-RI-MALLS) showed that dry-milled rice starch samples contained lower amounts of the high molecular weight portion of starch (amylopectin) than wet-milled samples. The molecular weight of both amylopectin from dry-milled rice starches (0.95-1.7 ∞ 10 7 Da) was lower than that of wet-milled rice starches (1.11-1.90 ∞ 10 7 Da), suggesting that the dry-milling process caused a higher degree of starch fragmentation than the wet-milling process.


The aim of this paper is to reflect on the metaphor of 'musical language' in order to find a satisfying paradigm for musical expressiveness. First, I will review the idea of music as 'language of emotions'. Then, I will present some authors from continental tradition, with particular attention to Giorgio Agamben's reflection on the link between music and Stimmungen , seen as prelinguistic moods which determine the orientation of the human being. I will refuse Agamben's approache and I will present Wittgenstein's comparison between musical and linguistic understanding, in which the concept of gesture is central. In conclusion, using Luciano Berio's and Guerino Mazzola's reflections on musical gesture, I will propose a gestural paradigm for understanding musical expressiveness. I will indicate in the complexity of musical gesture a synthesis between bodily immediacy and cultural tradition that will help to refuse both the linguistic paradigm, based on the concept of 'musical meaning', and the pre-linguistic model of musical expressiveness, which take back to the platonic theory of ethos.


We examine the evolution that the magnetic resonance accelerator, or cyclotron, has undergone in 50 years. In the presentation we note the most essential points of development of these accelerators. We note individual instruments that have made possible further progress in the design of cyclic accelerators. We discuss the requirements imposed on contemporary accelerators.


The superconducting properties of binary and ternary niobium compounds for rf applications are investigated. The materials under study are niobium nitride (NbN), niobium‐titanium nitride (NbTiN), and niobium tin (Nb3Sn). Preparation techniques of the compounds are discussed. NbN and NbTiN are obtained by thermal reaction of bulk Nb in nitrogen atmosphere. Nb3Sn has been obtained using a technique originally developed for high‐field magnet fabrication and modified to be applied to rf cavity production. The experimental apparatus and measurement technique are described. In particular the raw experimental data have been carefully analyzed to obtain important informations on fundamental material parameters. The effect of field penetration in the superconductor and the influence on the experimental results of the normal metallic substrate on which the superconductor is grown is also considered. The measurements show that NbN and Nb3Sn are effectively potentially good materials for rf applications due to their ...


Planetesimal formation is still one of the most important unresolved problems in planetary science. In this study, I propose a scenario for planetesimal formation. Sublimation of H2O ice in an icy dust aggregate leads to the concentration of silicate dust core particles at a particular heliocentric distance. I show that the dust column density can reach the critical density required for the self‐gravitational instability of the dust layer. The dust surface density increases locally by a factor of 10 in 6,000 years for 10 cm‐sized aggregates. The timescale is shortened by the sublimated H2O vapor.


The busbar protection set based on microcomputer has been much mature,and the current way to select the fault buabar is based upon total differential and partial differential.The article introduces two arithmetic of partial differential,and analyses the method of using compare the current vector of coupler breaker,and provides sampling arithmetic and vector arithmetic.Using two methods together makes the protection set select fault busbar more reliable.


Through a literature review, this paper aims to present the approach and impact of blockchain technology and industry 4.0 at autonomous vehicles. The number of literatures visualized at the Vosviewer software shows a strong connection between the respective keywords, in special a gap in developing literatures related to autonomous vehicle and blockchain. Furthermore, it can be seen a lot of interaction between automating cars and IoT (Internet of Things) sensors / devices from the industry 4.0, bringing to the fore the autonomous vehicle's system vulnerability. However, blockchain technology is introduced as a feasible solution for data's security and privacy, opening opportunities for future research in exploring its application in different level of driver assistance technology and the investment involved.


The purpose of this study is to identify the effect of three clothing cues(jacket color, skirt color, and tone of dress) on female impressions. The experimental materials developed for this study are a set of stimuli and response scales. The Stimuli are If color pictures manipulated with three cloth...


In the letter we present a set of universal probability curves that relate the array error tolerance, illumination function, achievable sidelobe level and the designed sidelobe level. We show that this set of probability curves can be used to find a lower designed sidelobe level to achieve a better error tolerance. The relations of array directivity gain and beamwidth with respect to illumination function are also discussed. These parameters can be conveniently used for this design procedure without detailed knowledge of the array illumination.


In recent years, the Indian economy has undergone a number of reforms, resulting in a more market-oriented economy. Particularly after the Government of India has taken steps towards liberalization and Globalization of the economy, the size of Indian Corporate is becoming much bigger and accordingly the expectations of various stakeholders are also increasing, which can be satisfied only by good Corporate Governance. Corporate governance refers to the set of systems, principles and processes by which a company is governed. They provide guidelines as to how the company can be directed, or controlled such that it can fulfill its goals and objectives in a manner that adds to the value of the company and is also beneficial for all stakeholders in the long term. Stakeholders in this case would include everyone ranging from the board of directors, management, shareholders to customers, employees and society. The management of the company hence assumes the role of a trustee for all the others. Recent corporate scandals have eroded investor trust to some extent in corporate reporting. To reduce corporate malfeasance and protect investors, Sarbanes-Oxley Act of 2002 (Sarbanes-Oxley) and Revised Clause 49 of Stock Exchange Listing Agreement were promulgated by the regulators in the Unites States and India, respectively. These legislations defined a new system of checks and balances to rebuild investor confidence. The whole corporate governance issue is popping its head up again after the pandemonium over the sordid Satyam-Maytas business. Much has been written, debated and blogged over the proposed $1.6-billion merger between the two companies, but one can bet his last dollar that the last word has not been spoken yet. The governments in Delhi, the regulators in Mumbai, the shareholders in New York have all jumped in and expect some more fireworks over the next few weeks. It is in this context that Corporate Governance has become the most debatable issue today. The Article analyses the difference in the Indian Capital Market Law and the International Standards of Corporate Governance. Part I of this article begins with a brief insight into the Indian and International Standard of Corporate Governance. Part II of this Article outlines some key developments in Indian Corporate Governance by way of background. Part III of this paper discusses the Clause 49 - the heart of Corporate Governance in India and the Sarbanes Oxley Act of the United States. It also analyses the problem with the Indian Legal System in this context. It also provides a brief of all the Indian Committee reports so far in the area of Corporate Governance. Part IV discusses the recommendation of the Cadbury Committee Report and Higgs Report. It throws light on the plausible reasons for the recent failure of governance in several US companies and contrasts that with the position existing under Indian Corporate Law (much of which predates 49). Part V concludes with some recent trends in Corporate Governance in India, US and UK and the Impact of all these Reports and regulations in Corporate Governance.


Hay bales, live reindeer, foraged gifts and eco-friendly decorations – some nurseries are rejecting traditional nativities in favour of more community-conscious ideas. By Annette Rawstrone


This paper is to classify the water resources system sustainable utilization according to projection function value through transferring multi dimension data indexes into low dimension space by using projection pursuit cluster (PPC) model. The result shows that the method can construct a characteristic index, and the main impact effects can be analyzed according to the result. The model is qualified with simplicity and can provide a new approach for water resources system sustainable development


GaN epitaxial layers with buffer layers were grown on (0001) sapphire substrates by direct reaction of Ga and NH3 at the low temperature of 750°C. The buffer layers were deposited on the substrates by using GaN-coated graphite boats at temperatures below 750°C in Ar flow before the epitaxial layers were grown, where GaN films coated on the graphite boats acted as a source material in the deposition of the buffer layers. The Hall mobility of the GaN epitaxial layers grown with the buffer layers was approximately 50 cm2/(V·s), whereas that of the GaN epitaxial layers grown without the buffer layers was approximately 2 cm2/(V·s). The crystallinity of the GaN epitaxial layer was improved by being grown on the buffer layer. The buffer layer deposited by using the GaN-coated graphite boat played a role similar to that of the buffer layer deposited at low temperature by conventional metal-organic chemical vapor deposition.


Due to its unique properties of dendrimers as well as with high-level groups, a special ability to carry drugs. In this study compared the interaction between the two generations of poly (amidoamine) PAMAM (G3and G5) dendrimers and the drug 6-mercaptopurine (6-MP) and the drug entrapment within the structure of dendrimers the electrostatic and covalent complexation of drugs to the dendrimer surface have been studied. The use of drug-dendrimer complex enhanced drug solubility and bioavailability of the drug.


Many biological, hydrological, and geological processes are interactively linked in ecosystems. These ecological phenomena normally vary within bounded ranges, but rapid, nonlinear changes to markedly different conditions can be triggered by even small differences if threshold values are exceeded. Intrinsic and extrinsic ecological thresholds can lead to effects that cascade among systems, precluding accurate modeling and prediction of system response to climate change. Ten case studies from North America illustrate how changes in climate can lead to rapid, threshold-type responses within ecological communities; the case studies also highlight the role of human activities that alter the rate or direction of system response to climate change. Understanding and anticipating nonlinear dynamics are important aspects of adaptation planning since responses of biological resources to changes in the physical climate system are not necessarily proportional and sometimes, as in the case of complex ecological systems, inherently nonlinear. Published by Elsevier B.V. Ke.ywords: Nonlinear dynamics; Thresholds; Ecosystems; Climate change; Natural resource management * Corresponding author. Tel.: +1 337 266 8500, fax: +I 337 266 8610. E-mail address: email@example.com (V.R. Burkett). 1476-945Xf$ see front matter. Published by Elsevier B.V. doi:10.1016/j.ecocom.2005.04.010 358 VR. Burkert et al./Ecological Complexity 2 (2005) 357-394


Backgroundthe concept of status of health has been considered more aggressively , and therefore, more attention has been paid to the integration of the different aspects of health quality in health assessment ,the study aims to assess prevalence of MSDs of housewives in Delhi and Noida Method: 100 Housewives of age 25-35, primi gravida and no pregnancy at time of survey were selected . Standard Nordic Questionnaire was employed to assess prevalence of MSDS. Descriptive statistics were used to analyse the data Result:100 % housewives were affected by musculoskeletal disorders in one or more body region. The severity of MSDs last 12 months respondents indicated that they were prevented from carrying their normal activities with Lower back ( 60%), Shoulder (42 %), Upper back (38%), Neck (35%), Wrist/hand (29%), Ankle/Feet (26%), Knee & Thigh/Hips/Buttocks (20%) and Elbow (18 %). Conclusion: it can be concluded from the present study that selected housewives were having MSDS in one or more boy region last 12 months and last seven days. Severity of MSDs is also high for last 12 months.


Medical imaging requires great integrity of content since any change in the image even in a slight amount might affect the diagnosis. Semi-fragile watermarking could be the best technique to provide an efficient image authentication tool for medical images. In this paper, we propose a semi-fragile watermarking technique for the tamper proofing of still images that can tolerate JPEG lossy compression to a predetermined lowest quality factor and rejects any replacement process. We also present comparison performance for the proposed algorithm to eight other common techniques.


Thank you very much for reading the catholic bible study handbook. As you may know, people have look hundreds times for their chosen books like this the catholic bible study handbook, but end up in harmful downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they are facing with some infectious bugs inside their laptop. the catholic bible study handbook is available in our book collection an online access to it is set as public so you can download it instantly. Our book servers saves in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the the catholic bible study handbook is universally compatible with any devices to read.


&NA; Massey, C.D., J. Vincent, M. Maneval, M. Moore, and J.T. Johnson. An analysis of full range of motion vs. partial range of motion training in the development of strength in untrained men. J. Strength Cond. Res. 18(3):518–521. 2004.—The purpose of this investigation was to compare partial range of motion versus full range of motion training in the development of maximal strength. The bench press was used as the criterion measurement. The study was conducted over a 10‐week period with training sessions occurring twice per week. Subjects were divided into 3 groups. Group 1 (N = 11) trained with 3 full range of motion sets on the bench press. Group 2 (N = 15) trained with 3 partial range of motion sets. A partial repetition was defined as one that is beyond the sticking point 2 to 5 inches from full extension of the elbows. Group 3 (N = 30) trained with a combination of partial and full range of motion sets. All subjects were pre‐ and posttested on the bench press through a full range of motion using a 1 repetition maximum. Each of the 3 groups demonstrated statistically significant increases in strength from pre‐ to posttest. No differences were found between groups. These findings appear to suggest that partial range of motion training can positively influence the development of maximal strength. Therefore, those involved in the strength and conditioning profession can confidently including this method as an adjunct to their normal training protocols when working with individuals similar to those found in this investigation. It is suggested that additional research be conducted to further establish the effectiveness of partial range of motion training in developing maximal strength.


Research on the polarization method was performed to determine the effect of ozonation on the change in the polarization angle. In the previous studies, the change in the polarization angle would be greater with the longer time of VCO ozonation. This study aimed to determine the effect and the relation of ozonation flow rate, ozonation duration, ozone dose, and viscosity on the changes in the transmission polarization angle on VCO. The sample used is VCO, which was ozonated with a constant volume and varied by its flow rates and ozonation times. The parameter measured from VCO is the change in the transmission polarization angle. Red and green diode lasers with a power of 5 mW were used as light sources. The results showed that the ozonation affects the value of the change in the polarization angle. The ozonated samples (B, C, D) has an average change in the polarization angle of 1.10° ± 0.07° (green laser) which is greater than the un-ozonated sample (A) of 0.60° ± 0.05o (green laser). The wavelength also affects the value of the change in the polarization angle of the VCO. Samples using a green laser have a greater change in the polarization angle than the red laser with an average of the change in the polarization angle in sample D are 1.50° ± 0.06° (green laser) and 1.40° ± 0.06° (red laser). The ozone dose in the sample affects the value of the change in the polarization angle. The larger the ozone dose results in the increasing value of the change in the polarization angle. The viscosity value also affects the change in the polarization angle of VCO. The greater viscosity results in the greater value of the change in the polarization angle.


Our purpose in undertaking this study was to determine in detail the topography of the cerebral lesions of acute poliomyelitis based upon the systematic examination of a sufficiently large number of specimens to furnish a true average picture of the pattern of the disease, and to place the peculiarities of individual cases in proper perspective. It is recognized that this plan is not highly original. During the past several decades there have been numerous reports on the pathology of poliomyelitis. Many of these are based on one or a few cases, examined with varying thoroughness. The relatively few more detailed studies fall generally into two groups. One presents rather comprehensive conclusions based upon examination of random sections from a considerable number of cases. In the other the authors have subjected one or two specimens to a fairly intensive examination, generally directed toward confirming some one theory of pathogenesis. We have encountered only two reports in which a substantial number of brains were examined systematically and the results reported in adequate detail. One is the careful and elaborate investigation of Horinyi-Hechstl based upon 24 complete central nervous system specimens from the I93I-I933 outbreaks of poliomyelitis in Budapest. The other is a description by Swan2 of 6 brains from South Australia in I937. Although only one lateral half of each brain was sectioned, the results are presented in considerable detail. Where possible we shall compare the findings of these two authors with our own in the discussion to follow. For reasons of convenience we have arbitrarily divided this study into three sections: lesions in the medulla oblongata, described in this paper; lesions in the pons and cerebellum, and lesions in the midbrain, basal ganglia, and cerebrum to be discussed in two subsequent publications.


Although the eighteenth century spoke bravely of internationalism in science, its scientists were put under heavy pressure by the rise of the nation-state. Ease of com munication in the nineteenth century made it seem as if sci ence were the product of an international community, while at the same time science was becoming more dependent on nationally divided institutions for support. When in the twentieth century the free flow of information ceased, it be came clear how closely science was tied to the various national units. The same pattern can be traced in the relation of basic to applied research. The eighteenth century saw the two brands of research as closely linked, but in the nineteenth spe cialization drove the two activities wide apart to form separate traditions. In the twentieth century military problems brought basic and applied research together again. Likewise the same pattern can be traced in the evolution of institutions within national units. The eighteenth century could envision com pre...


Spatiotemporal characteristics of drought based on the Standardized Precipitation Index (SPI) in the Liao River basin (LRB) are investigated in this study. High autocorrelation in SPI seems to lend itself to drought prediction. Drought is becoming more frequent, widespread, and severe in the LRB during the past several decades. Major factors affecting drought in this basin are analysed by investigating relationship between SPI and several circulations including western Pacific Subtropical High (WPSH), East Asian Summer Monsoon (EASM) and El Niño‐Southern Oscillation (ENSO) indices. Different correlation patterns between WPSH indices and SPI are obtained. Several significant positive correlations between the area, intensity of WPSH and SPI are observed in the west and the centre of the study area, while negative correlations are observed in the east. Reverse patterns are observed in the correlation between the ridge of westward longitude of WPSH and SPI. Corresponding lag‐correlation is dominated by positive correlations between the area, intensity of WPSH and SPI, and by negative correlation between the ridge of westward longitude of WPSH and SPI. EASM is mainly negative related with drought in the east of the LRB. Significant positive correlation between ENSO and SPI is mainly located in the east while negative correlation is located in west of the basin. Lag‐correlation (with lags of 1 to 12 months) between them is also investigated and results show that significant negative correlation is located in a broad area extending from the west to the centre of the basin, while less positive correlation is observed with the increase of lags. The possibility of employing general circulation models (GCMs) for drought prediction is discussed based on the above analyses. Copyright © 2011 John Wiley & Sons, Ltd.


Blind people are facing many problems in their day-to-day life . They find it very difficult to read books as well as to recognize the object in front of them. Previously braille method helped them to read using their fingers, this is completely eliminated by this method. We add some extra features to aid visually impaired persons. They can walk on their own as well as without blind stick..This method helps the blind people to read themselves without using their hands. Without touching the objects, they come to know about the things beside them. This technique acts as a third eye for the blind people. They can even walk across the road without the use of blind stick. By implementing this method, they will get a chance to overcome the problems faced by them in the


Heat-pump-centered integrated community energy systems (HP-ICES) are energy systems for communities which provide heating, cooling and/or other thermal energy services through the use of heat pumps. Since heat pumps primarily transfer energy from existing and otherwise probably unused sources, rather than convert it from electrical or chemical to thermal form, HP-ICES offer significant potential for energy savings. By powering these heat pumps with nonscarce fuels, the use of which would be impractical in most conventional systems, less-abundant fuels including natural gas and oil can be conserved. Secondary benefits of HP-ICES include reduction of adverse environmental effects as compared to conventional systems, reliable production of services in contrast to the increasingly frequent utility curtailments and interruptions, and delivery of services to consumers at costs lower than those for conventional systems (including acquisition, operation, and maintenance costs). The objective of this multiphase HP-ICES project is development and demonstration of concepts leading to one or more operational systems by the end of 1984. The findings from the System Development Phase of the program are reported. Information is included on the HP-ICES concept; its application potential; variations in the basic HP-ICES concept which could lead to improved performance; applications of the concept to specificmore » communities; design; economics; environmental impacts; and component testing requirements. (LCL)« less


Objective To study the relationship between the expression of NF-κB and its biological behavior,as well as its correlation with the expression of COX-2 in colorectal carcinoma.Methods The expression of NF-κB and COX-2 were detected by immunohistochemical staining in 103 cases of colorectal carcinoma tissues,and compared with those in 103 cases of normal colorectal tissues.Results ① The positive rate of NF-κB protein was 66.02%(68 /103) in colorectal carcinoma tissues and 22.33%(23 /103) in normal colorectal tissues.There existed significant difference between the two groups(P0.01).The positive rate of NF-κB protein was higher in tumor than that in normal colorectal tissues.The positive rate of COX-2 protein was 45.63%(47 /103) in colorectal carcinoma tissues and 10.68%(11 /103) in normal colorectal tissues.There existed significant difference between the two groups(P0.01).The positive rate of COX-2 protein was higher in tumor than that in normal colorectal tissues.②The expression of NF-κB in colorectal carcinoma tissues correlates with the metastasis of lymph nodes and clinical stage and diffential grade(P0.01).③The expression of COX-2 in colorectal carcinoma tissues correlates with the metastasis of lymph nodes and clinical stage and diffential grade(P0.01).The expression of NF-κB and COX-2 in colorectal carcinoma were not significantly related to the sex of patients or the age of patients and so on(P0.05).④The expression of NF-κB was positively correlated with COX-2(= 11.2457,P0.01).Conclusion The abnormal expression of NF-κB and COX-2 were important genetic events associated with the genesis and development of colorectal carcinoma.


This paper focuses on the internationalisation of innovative capability; not R&D and patenting capabilities or on production capabilities alone. It examines whether internationalisation of innovative activity has spread to firms in the electronics industry in Malaysia where Malaysia is among the world's largest exporters of semiconductor devices and 96.3% are foreign-owned. Conventional literature states that it has not occurred, as production outpost in countries like Malaysia are not technologically advanced and do not have the conditions in terms of skills and internal capabilities for this to occur. If there is evidence to the contrary, how long did this take? To operationalise key concepts, the paper has developed a comprehensive classification to measure technological capabilities of firms in the electronics industry and learning rates (speed) using the historical timeline of firms. The analysis of TNC subsidiaries and local firms shows that internationalisation of innovative capabilities has occurred to some extent.


W epresenttopologicalfeaturesofthem agneticresponse(orbitaland spin)of a two-dim ensionalnon interacting electron gasdueto inhom ogeneousapplied m agnetic (cid:12)elds. These issues are analysed from the point of view of the Index theory with a specialem phasison the non perturbative aspectsofthis response.Thelim iting caseofa A haronov-Bohm m agnetic(cid:13)ux lineisstudied in detailsand the resultsare extended to m ore generalsituations.


New criteria as a generalization of the resultant of two polynomials are given for relative primeness of polynomial matrices together with system theoretic interpretations and unification of the existing and new criteria.