Objective To explore the clinical diagnosis and management of hepatecellular adenoma(HA). Methods Seventeen HA cases treated in our hospital from Janurary 1986 to June 2007 were studied retrospectively.The clinical and pathologic data were reviewed. Results Of 17 patients,9 were male and 8 were female with median age of 46 years.None of the female patients had a history of oral contraceptives.Most patients were agymptomatic.Preoperative liver function test and AFP serum test were normal.Preoperative imaging study yielded deftnite diagnosis in only a fraction of patients.All 17 cases underwent surgical resection and the postoperative course is uneventful.All cases were followed up ranging from 6 to 252 months.Recurrence was not found.Pathology reported atypical hyperplagia in 2 cases and with malignant transformation in 1 case. Conclusions The diagnosis of HA is exclusive and dependent on clinical data,laboratory test and radiography.HA has a tendency to malignancy.Surgery is recommended in all cases.

Key words:
Liver neoplasms; Diagnosis; Therapy;  Adenoma


This paper sets forth the different translating skill focusing on vocabulary and various rhetorical features in English news translation from the perspective of semantic translation and communicative translation in Newmark's Translation Theory.It illustrates vocabulary translation and rhetorical translation in English news as well.At the same time,it puts forward some theoretical significance and guiding role in semantic translation and communicative translation of English news,which are feasible.


Abstract A simple assembly line balancing problem is considered provided that number m of working stations is fixed. In such a problem, denoted as SALBP-2, it is necessary to minimize a cycle time for processing a partially ordered set of operations V = [1, 2,…, n] on a set of m linearly ordered (working) stations. An initial vector of the processing times t = (t1, t2,… ,tn) of the operations V is given. And for each automated operation processing time ti cannot vary during a life cycle of the assembly line. For a subset V V of the manual operations j ∈ V, processing times tj may vary, since different workers may have different skill, experience, etc. We investigate a stability of the optimal line balance of the simple assembly line with respect to simultaneous variations of processing times tj of manual operations j ∈ V. An optimal line balance is stable if its optimality is preserved for any sufficiently small variations of processing times tj, j ∈ V. We propose an enumerative algorithm and a program in C++ for constructing all the stable optimal line balances for the problem SALBP-2. Computational results for the modified benchmark instances have been presented.


The effective long-term remediation of contaminated sediments presents a particular challenge, since the large volume and the often diverse range of contaminants in these materials makes many of the traditional remediation techniques uneconomic. Future risk assessments of contaminated sediments should focus on assessing possible chemical changes in the stored sediment (e.g. redox changes and acid production) that could lead in the long term to contaminant remobilization. New biological criteria of contaminated sediments are also needed. These risk assessments must be undertaken with the potential remediation methods in mind. Priority needs to be given to the application of new geochemical engineering techniques, including chemical stabilization by additives and storage under permanent anoxic conditions, that optimize the long-term chemical stability of contaminated sediments.


The results of my study on the histology and the innervation of the nasal cavity and the snout of 4 and 5 month cattle fetus may be summarized as follows.The structure of the snout is specific in that the epithelium covering it is a thick bladder-like epithelium, very large papillae being grown into it from the propria, and that the submucosa contains very well-developed snout glands, of which the ducts run out through the papillae. The snout has on the other hand sinus hairs growing on the lateral side, so that it must in a part originate in haired skiu, too.The proper nerves supplied to the snout are surprisingly well developed and show formation of plexus submucosus, plexus laminae propriae and intrapapillar plexus. These plexuses are composed of many thick sensory fibres and a few fine vegetative fibres, the latter coming into anastomosis with the perivascular plexus. The terminations of the vegetative fibres here also form STOHR's terminal reticula, which are particularly well developed around the snout glands and the blood vessels and stand in control over various tissue cells by direct contact.The sensory terminations found in the snout are of branched type formed subepithelially, but a part of the sensory fibres form intraepithelial fibres. The subepithelial terminations are always of simple branched type, and the terminal fibres show frequent change in size, to end in sharp or sometimes in blunt points. The intraepithelial fibres comprise both fine and thick ones, of which the fomer mostly run simple courses, but the latter run looping courses, often showing simple glomerular arrangement. The intraepithelial fibres are usually of unbranched type, but branched ones are not rare, either.Near the orifice of the vestibulum nasi, there is a special area with vibrissae growing on it. This part probably corresponds to the pars cutanea in the human nose, but in bovine fetus it does not belong to the haired skin, but together with the snout to the mucous membrane, for its epithelium is 2-3-folds thick as the epidermis and is nothing different from the stratified flat epithelium of the vestibulum nasi of the other parts. It is a part of specific haired mucosa.The vestibulum nasi, outside this specific haired mucous part, is lined near the orifice by a horn-plated hornified mucous membrane, then to the back, by a nonhornified mucous membrane nearer the pars respiratoria, where the epithelium becomes thinner. Then comes a transitional part covered by a 4-5-rowed cylindrical epithelium and more backwards the pars respiratoria covered by a 2-3-rowed ciliated epithelium. In the hornified mucosal part the papillae are in good development but they become poorer backwards and in the next non-hornified mucosal part, they are no more to be found. The nasal glands come into appearance in cat and dog only in the deep part of the vestibulum nasi, but in cattle they are found all over the vestibular wall. The pars respiratoria has nasal glands and venous plexus in its subepithelial connective tissue, as in cat and dog.The sensory innervation of the specific haired mucous part of the vestibulum nasi is very powerful as in the case of the snout of the same nature. A part of the sensory fibres in the well-developed nerve plexus formed in the submucosa containing hair roots form plexus-like terminations in the SETO's so-called hair-nerve shields or tubes quite as in common haired skin. The remainder of the fibres, unlike in common haired skin, run further into the propria and end in branched terminations. Their terminal fibres sometimes run further into the epithelium to end as short intraepithelial fibres.The sensory innervation of the vestibulum nasi in general is better in cattle fetus than in man. The nearer to the orifice, the part is the better provided with sensory fibres and their terminations, and when we go over the transitional part into the pars respiratoria, the innervation becomes rapidly poorer.


Cells can distinguish between different types of mechanical signals, such as stretch (tension), pressure (compression), and shear, to guide mechanosensitive cellular activities. Cell culture systems with controlled delivery of a mechanical input such as substrate strain, hydrostatic pressure, or fluid shear stress are used for the in vitro application of these forces. The work reported here uses a system that imparts equibiaxial loading on a flexible substrate to study cell response to stretch, similar to the Bioflex in the Flexcell [1] family of products. The objective of this study is to introduce an analytical (closed-form) solution of the relationship between the substrate strain and pressure under small strains, less than 2%. The solution is derived from the superposition of two elastic responses induced in the equibiaxial strain culture system after applying pressure.© 2009 ASME


Introduction: Due to the paucity of research that specifically examines the non-use of condoms, during sexual encounters, as a maladaptive coping strategy for stress among college students; the purpose of my study, is to determine if there is an association between perceived high levels of stress and the decreased likelihood of condom use during sex among students at the University of Kentucky. Method: The cross-sectional descriptive study investigated health behaviors and attitudes towards health behaviors in a sample of 7,000 University of Kentucky students enrolled in courses for fall 2013. Participants were randomly selected to partake in an anonymous online health survey. The study is geared toward gaining an understanding between high levels of stress and non-condom use during vaginal, oral, and anal sex among those students at the University of Kentucky. The variables measured in the study were all contributing factors towards perceptions of overall health. The variables of interest were stress, sex, and non-condom use; stress being the correlate variable, and non-condom use being the outcome variable. I am focusing my attention only on those respondents who have been sexually active within the last 30 days, excluding responses from sexually naive respondents. Results: While the chi-square analysis reported certain variables were significantly associated with non-condom use for vaginal and anal sex, logistic regressions run for vaginal, oral, and anal sex reported that high stress levels did not appear to predict not using condoms during vaginal,


There have been a lot of debates, within the International Civil Aviation Organisation (ICAO) GNSS Panel (GNSSP) group of experts, on the proper way to ensure SBAS user safety while at the same time respecting the high availability requirement. The group finally validated a method at the GNSSP Seattle meeting in June 2000 which is reproduced in the GNSS Standards And Recommended Practices (SARPs) to be published in November 2001. However, if the technical relevant information for a SBAS system designer to implement the SBAS integrity concept is fully described in the SARPs, only the strict necessary information is reported there and it is quite difficult to a non specialist to properly understand this important concept. Therefore, since the SBAS integrity concept is quite specific and new, some kind of complementary information to the SARPs was felt desirable. This paper tries to address this concern and will also illustrate how the integrity is being managed through the European EGNOS SBAS project.


The seal of Utopia stamped the history of Mexico from its colonial origins. Thomas More's Utopia was published at Louvain in 1516, three years before Cortez disembarked on the coast of the Gulf of Mexico, and twenty years later Vasco de Quiroga, the first bishop of Michoacan, attempted to realise Utopia in his diocese. When, in the first years of the last century, the learned traveler Alexander de Humboldt made investigations which resulted in A Political Essay on the Kingdom of New Spain, he was able to verify the Indians' continuance of the country of the &dquo;venerable Vasco&dquo; (tata Vasco).1 Besides a hagiographic legend (one could cite a great many of them) and besides an equally significant regional tradition, the historian establishes that the


Head Start programs must meet federal performance standards or may now face a process of "recompetition", a situation where the current grantee could lose the Head Start program to other agencies. This article is based on interviews with Head Start directors who were faced with the threat of recompetition, but were able to turn around their programs in time to avoid the possibility of losing them. A model for Head Start turnaround emerged in these interviews and is shared in this article.


Inhibitory effects of 200 medicinal plants on elastase activity were screened. Among the 200 plants, six plant extracts exhibited more than 65% of inhibition on elastase activity by their total methanol extracts at 1, 000/ as a final concentration. For six active plants including Areca catechu, Cinnamonum cassia, Myristica frograns, Curcumma longa, Alponia katsumadai, and Dryopteris crassirrhizoma, the inhibitory effects of their comsituents were examined on the activity of human leukocyte elastase, hyaluronidase and lipid peroxidation. In lipid peroxidation assay using TBA method, three of the 6 plants including Curcumma longa, Areca Catechu and Alponia katsumadai exhibited more than 70% of inhibition at the concentration of 1, 000/, but only one plant, Areca Ctechu showed high inhibitory effect on hyaluronidase activity. The results suggest that medicinal plants showing several biological activities may be potent inhibitors of anti-aging process on skin and that might be useful for application in cosmetics.


The Council of the North Atlantic Treaty Organization (NATO) met in joint session with the military committee on March 17, 1958, to exchange views on NATO defense needs. In a later meeting the Council, after studying the possible convening of a summit conference, approved a draft declaration, which was presented to the Soviet government on March 31, setting forth the western position on the preparation of such a conference. The message stated that preparatory work, such as exchanges through diplomatic channels leading to a meeting between foreign ministers, was necessary to examine the position of the various governments on the major questions at issue and to establish what subjects should be submitted for examination by heads of government. The foreign ministers would reach agreement on the date and place of the summit meeting and decide on its composition. The note stated that if this procedure were acceptable to the Soviet government it was suggested that diplomatic exchanges should start in Moscow in the second half of April.


Chapter 1: Basic Concepts of Pharmacology Chapter 2: Autonomic Pharmacology Chapter 3: CNS Drugs Chapter 4: Anti-Inflammatory Agents Chapter 5: Anesthetics Chapter 6: Endocrine Drugs Chapter 7: GI/GU Agents Chapter 8: Cardiovascular Drugs Chapter 9: Hematologic Agents Chapter 10: Chemotherapy Chapter 11: Antimicrobials Chapter 12: Toxicology Review Questions


These cases are drawn from eight clinics at present engaged in a study of the effect of penicillin on late syphilis, under the general auspices of the Committee on Medical Research of the office of Scientific Research and Development. These, with the names of the responsible investigators, are as follows: University of Pennsylvania (John H. Stokes, M.D.), Cornell University (Walsh McDermott, M.D.), Mayo Clinic (Paul A. O'Leary, M.D.), Boston Psychopathic Hospital (Harry P. Solomon, M.D.), University of Michigan (Udo J. Wile, M.D.), Bellevue Hospital (Evan Thomas, M.D.) and Johns Hopkins University (J. E. Moore, M.D.). Associated with each of them are various co-workers and assistants too numerous to mention here, but to whom due credit will subsequently be given. Penicillin has distinctly beneficial serologic and clinical effects on neurosyphilis, including early and late manifestations, not excepting tabes and paresis, and including asymptomatic neurosyphilis. Its action on gummatous manifestations of skin,


Compuational fluid dynamics (CFD) is used to help understand the gas flow characteristics in the wave soldering process. CFD has the ability to calculate (1) heal transfer, (2) fluid dynamics, and (3) oxygen concentration throughout the wave soldering machine. Understanding the impact of fluid dynamics on oxygen concentration is important as excessive oxygen at the solder bath can lead to high dross contents and hence poor solder joint quality on the printed circuit board. This paper describes the CFD modelling approach and illustrates its capability for a machine which has nitrogen injectors near the solder bath. Different magnitiutes of nitrogen flow rates are investigated and it is demonstrated how these effect the oxygen concentration at the bath surface.


To increase accuracy rate of sign language recognition,a recognition method based on Hu invariant moments and euclidean distance of sign language image is introduced.Firstly,its 7Hu moments are calculated,the recognition of 30 letter gestures is performed by computing distance between matching and template image to recognize image.The algorithm remains constant when the image rotates,transfers and scales.The method overcomes the impact of illumination in capturing image and marginal information loss caused by image segmentation.The experiments show the validity of this method especitaly a successful result of images with a high rate of pepper-and-salt noise.


A k-uniform hypergraph H = (V,E) consists of a set V of vertices and a set E of hyperedges (k-hyperedges), which is a family of k-subsets of V . A forbidden k-homogeneous (or forbidden k-hypergraph) access structure A is represented by a k-uniform hypergraph H = (V,E) and has the following property: a set of vertices (participants) can reconstruct the secret value from their shares in the secret sharing scheme if they are connected by a k-hyperedge or their size is at least k + 1. A forbidden k-homogeneous access structure has been studied by many authors [1,2,10,45] under the terminology of k-uniform access structures. In this paper, we provide efficient constructions on the total share size of linear secret sharing schemes for sparse and dense k-uniform access structures for a constant k using the hypergraph decomposition technique and the monotone span programs.


Gaelic-medium primary education begins with an immersion phase in which children study all of their subjects through the medium of Gaelic. English is typically introduced towards the end of Primary 3, but Gaelic remains the predominant language of learning throughout primary. The aim is that pupils achieve broadly equal competence in Gaelic and English by the end of primary school. At the secondary school stage, pupils who were in Gaelic-medium primary education typically study Gàidhlig (Gaelic as a subject for fluent speakers). In some secondary schools, other subjects are also provided through the medium of Gaelic for Gaelic-medium pupils.


Based on KOR a new rekeying strategy and protocol(called KOR~+) are first proposed and compared with KOR in this paper.Then two formulae of the average encryption costs of a key server utilizing KOR~+ and UOR are established respectively provided that the key trees are full and balanced.Finally,optimal key tree degrees are deduced analytically for both of them.


For distributed hash table (DHT) allowing clients to fill its DHT routing table, the processing method for responding to DHT message from DHT client is performed by the proxy processing agent having a plurality of nodes, receiving a DHT request message from the DHT client, generating at least one node identifier, comprising the steps of associating each node identifier to the IP address and port number, the combination of the IP address / port number, the plurality of corresponds to one node of the nodes, and transmitting the step, the DHT response message containing said at least one node identifiers and IP addresses and ports associated with it in DHT client, small Both and storing the IP address and port associated with it and one of the generated node identifier in connection with the DHT client.


Thispaperis8n addition /0 the limited liter-alurton iJuuse oj dream Il/O'Yk with jxllients luruing TlllIl1iple jJersOlwlity disorder(MPD). Drea ms call 1M used in clinical praclice (0: aid ill 1M ImakdolUn oJ barriers erected 10 block memories oj childhood abuse, rccognize alter per sonalities, control malevolent allers, (lnd identifj and reduce con flicts among personalities. An iIlustralivtl case report oj the treat ment of an alleged satanic ritual almse survivor demmlstm/es the vitiation of II perpetrator alter through dream worn. The baulnce of power within the host personality shifted as IIon-jJn'jJetrati"g per sonalities lined utJ to isolate the abuser.


Dry matter content in overground biomass in six varieties and four breeding populations of white clover (Trifolium repens L.) were studied at the Lithuanian Institute of Agriculture (Dotnuva) during the period 2001– 2003. In this study, the AMMI model was used with the objective of assessing dry matter content in the overground biomass of white clover genotypes, selecting stable genotypes and investigating genotype by environments (G × E) effects. The effects of environments, genotypes and G × E interaction were highly significant (P < 0.01). The first two bilinear AMMI model terms accounted for 88%. The biplot showed three groups of genotypes: Nos. 1123 and 1124 unstable but high-yielding; varieties 'Suduviai', 'Bitunai', 'Atoliai' and No. 1421 stable but low or medium yielding; variety 'Nemuniai', 'Rivendel' and No. 1435 unstable, low or medium yielding. To breed a new ecologically stable variety of white clover we intend to use the variety 'Nemuniai' and No. 1124 as initial material for hybridization. They have a high level of dry matter productivity but differ by GE response.


1 Institute of Earth Sciences, Academia Sinica, Taipei, Taiwan 2 Department of Geosciences, National Taiwan University, Taipei, Taiwan 3 Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, China 4 A.P. Vinogradov Institute of Geochemistry, Siberian Branch of RAS, Irkutsk, Russia 5 CCFS/GEMOC Key Centre, Department of Earth and Planetary Sciences, Macquarie University, Sydney, Australia


In this study, a comparison of two methods, the Selective UV Spectrophotometrical Method and Reduction with Hidrazine Method, for the determination of Nitrate ion in groundwater, was carried out. For this purpose, the results from all the drinking water collectings of the city of Olavarria, Argentina, were employed. Both methods present significant different means, but they don´t present significant differences in their variances.


We used two hand‐held gamma‐detecting probes (GDP) (Neoprobe™ 1000 system) capable of detecting small gamma emissions to monitor leakage in patients undergoing hyperthermic isolated limb perfusion (HILP) who received 800 μCi Technetium 99m pentetate through the perfusate. The percentage of gamma‐ray leakage was calculated by a simultaneous reading of two probes at 1‐minute intervals (one over the precordial area and one over the thigh) and this was compared to results of simultaneous blood sampling from the perfusate and systemic circulation at 15‐minute intervals for gamma well counting (GWC). The percentage of leakage recorded by the GDPs was essentially identical to that detected by the GWC (7.3% and 8.2%, respectively at the conclusion of the perfusion). The GDP gives an immediate and accurate indication of the percentage of leakage during HILP, making it a safer procedure.


We prove the last open case of the conjecture on the possible values of the first isotropy index of an anisotropic quadratic form over a field. It was initially stated by Detlev Hoffmann for fields of characteristic ̸= 2 and then extended to arbitrary characteristic by Burt Totaro. The initial statement was proven by the author in 2002. In characteristic 2, the case of a totally singular quadratic form was done by Stephen Scully in 2015 and the nonsingular case by Eric Primozic in early 2019.


The Red Sea and Aden rifts (or propagators) meet in Afar. Here we use remote sensing and field analyses to define the geology and structure of the southern part of the Red Sea propagator in Central Afar. This consists of the NW‐SE trending Tendaho Graben (TG) and the younger and active NW‐SE trending Manda Hararo Rift (MHR), partly within TG. Tectonic and volcanic activity within TG developed mostly between ∼1.8 and ∼0.6 Ma, with a stretching factor β ∼ 1.1, an extension rate ∼3.6 mm/yr and the fissural eruption of part (∼7000 km3/Ma) of the Afar Stratoid sequence (mainly basaltic lava flows and ignimbrites). MHR, before terminating southward, has a β ∼ 1.04 and an extension rate ∼1.2 mm/yr, and is associated with the emission of ∼600 km3/Ma of basalts in the last ∼0.2 Ma. These data suggest that after the exceptional amount of magma erupted between ∼1.8 and ∼0.6 Ma, magmatic and tectonic activity significantly decreased along the southern part of the Red Sea propagator in the last ∼0.2 Ma. This decrease coincides with the on‐land development and migration of the more active (inferred extension rate in the order of ∼10 mm/yr, as proposed in previous studies) Aden propagator, suggesting that spreading in Central Afar mainly occurred along one active propagator at any one time.


The stability of dopamine (DA) binding to BM3h-B7 and BM3h-8C8 was tested by incubating each protein with various amounts of DA at room temperature and measuring the absorbance difference between 430 nm and 410 nm over two hours (Supplementary Fig. 1). During this time, a decline of less than 5% was observed when 1 µM sensor was incubated in the presence of excess DA (800 µM). Optical changes were greater when sensor was incubated with subsaturating concentrations of DA (up to 22% signal change for 1.3 µM DA incubated with BM3h-B7), consistent with the predicted effects of DA oxidation (known to take place under ambient conditions) on the partial saturation of the sensor. To test the reversibility of DA binding to BM3h-B7 and BM3h-8C8, we acquired absorbance spectra of the proteins alone and with 400 µM DA before and after filtering the solutions through a 30 kDa cutoff centrifugal filter. Successive steps of filtering and resuspension restored the original, ligand-free spectrum (Supplementary Fig. 2). Rate constants for binding and unbinding of DA to BM3h-8C8 were estimated to be 3 x 10 3 M-1 s-1 and 0.02 s-1 , respectively, at room temperature in phosphate buffered saline (PBS). Association was measured by rapid 1:1 mixing of protein (4.8 µM) and DA solutions (0.6-2.5 mM), followed by absorbance spectroscopy in a Hi-Tech KinetAsyst SF-61DX2 stopped-flow spectrometer (TgK Scientific, Wiltshire, UK). Dissociation was measured by fast 1:100 dilution of a solution containing 100 µM BM3h-8C8 and 50 µM DA, followed by absorbance recording in a Spectramax M2e spectrophotometer (Molecular Devices. Sunnyvale, CA).


The concept of sustainable building incorporates and integrates a variety of strategies during the design and construction of building projects. Using green building materials and products in these stages promotes conservation of dwindling nonrenewable resources internationally. Bamboo as a construction material is popular in Southeast Asia. It is environmentally friendly and a renewable resource. However the application of bamboo in construction sites shocks western visitors even if they are construction professionals. This paper introduces the usage of bamboo in the construction industry in Southeast Asia, especially bamboo scaffolding. It indicates the reasons for bamboo scaffold popularity and introduces the process of bamboo selection, scaffold erection, maintenance, dismantling, and reuse. It also discusses the potentials of expanding bamboo scaffolding usage by mixing bamboo and metal.


This paper describes a method to suppress interference in a WCDMA transceiver in the digital domain and thus improve the sensitivity of the receiver. The interference is caused by the leakage signal from the transmitter and by fed forward information from the transmitter a replica of the interference can be created and subtracted from the desired received signal. An adaptive least mean square algorithm is used to estimate the correct amount of the interference and to provide tracking ability for temperature variations.


(57) Abstract: The present application relates to flame-retardant polycarbonate resin composition, an effective amount for, the flame-retardant aromatic oligomeric phosphate composition having a hydroxyl-terminated formula (I) (e.g., preferably includes a polycarbonate resin base material comprising about 5 wt% to about 15% by weight) of the resin base material (Wherein, R represents a hydrocarbyl group derived from an aliphatic diol or an aromatic diol, Ar is alkyl substituted or unsubstituted phenyl group, n is from about 0 to about 10, and phosphate composition is an amount that forms the main component, n includes a phosphate in the range of 0-1.).


The purpose of this research is to acknowledge the rights of convicted women and the elements existed within Penitentiary, with the fulfilment of the rights of convicted women, then the conduction of convicted women rights' fulfilment has been conducted well. Thus, any form of discrimination, repression, exortion, and bad treatment is not happening in the penitentiery, building hopes that they may return to their normal life and being accepted by the society. This research isconducted in Class II A Women Penitentiary of Sukamiskin, Bandung.The writer gained data through interviews and collecting data about the profile of Bandung Class II A Women Penitentiary and theoretical foundations  by studying books, scientific research, articles, and legislation which are related to the problems in the research object, and also taking direct data from a penitentiary. The summary of this research is related to several rights of convicted women wich were not enitrely fulfilled and conducted as stated in Legislation number 12 year 1995 about Penitentiary, which are: religion, treatment, education, health, food, complaint, media, library, premium, and family visits.


Antibiotic resistant bacterial population is a great threat for human as well as for other domestic animals. Unscientific use of antibiotics in clinical sectors create a selective pressure on bacteria that make bacteria resistant to a wide range of drugs. The current finding demonstrated the isolation and characterization of multi antibiotics resistant bacterial species from oil contaminated soil and its lateral gene transfer efficiency at different temperature. Among six bacterial isolates, the strain OD1 showed highest antibiotic resistant capacity was selected for further studies. Morphological, biochemical and 16S rDNA sequence analysis confirmed the bacterial strains as Alcaligenes faecalis strain OD1. It was recorded that antibiotics resistant gene transfer was highly dependent on temperature and showed maximum transfer efficiency at 25°C (9.6 ×10-6).


Subband coding (SBC) has been shown to be an effective method for coding monochrome images at low bit rates. SBC systems decompose the input image into a small number of decimated, spectrally disjoint subband images which are then coded by a variety of means. Reconstruction is performed by decoding and merging the reinterpolated subband images. This work investigates the application of the subband concept to the efficient coding of color images. The color representations are cast into a subband coding framework to form color image coding systems. Differential PCM and finite-state vector quantization methods are used in coding the subband images. Bit rates below 1 bit/pixel are obtainable for high-quality representations of 256*256 color images.<<ETX>>


Abstract Rationale: Hashimoto's encephalopathy (HE) is an autoimmune-mediated encephalopathy rarely seen in Graves' disease, with <20 cases reported previously, associated with elevated concentration of circulating serum anti-thyroid antibodies usually responsive to steroid therapy. Patient concerns: We present a HE case (25-year-old male) with Graves' disease, complicated by fever and pancytopenia. The patient presented with fever, gait impairment, delirium, agitation and disorientation. Diagnoses: Thyroid-related antibodies were elevated and brain magnetic resonance imaging confirmed symmetrical white-matter lesion. There was no evidence of infection or other reasons to explain all of his clinical manifestations. Hashimoto's encephalopathy (HE) is an autoimmune encephalopathy with various manifestations and the characteristic of elevated anti-thyroid antibodies and has no relationship to thyroid function. Interventions: The patient had nonspecific clinical manifestations and excellently respond to glucocorticoid therapy. The symptoms and the radiographic abnormalities disappeared after glucocorticoid therapy. Outcomes: We followed up with him for 5 years, in which there was no recurrence and his thyroid function continued to be normal. Lessons: It is important to evaluate thyroid function and related antibodies in patients present with neuropsychological symptoms to avoid delay in diagnosis.


To establish whether or not porphyrins have any photodynamic and/or non-photodynamic action on the spleen PBGase further experiments are needed assaying: 1) different types of porphyrins, 2) higher concentrations, 3) different irradiation energies, 4) different temperatures and 5) different exposure times


Pai syndrome is a rarely encountered disease characterized by findings of median cleft lip, facial skin polyps, nasal mucosal polyps and midline central nervous system lipoma. We report a case with prenatal detection of a pericallosal lipoma and a skin tag on the forehead. After delivery, the diagnosis was confirmed as a case of Pai syndrome.


As changes in healthcare occur over the next several decades, physicians will play key roles in shaping new policies as direct leaders of these changes. Psychiatrists possess unique skills gained in psychiatric training that make for superb potential leaders. Emotional intelligence, a term used in the business literature to describe traits essential for "great" leadership, comprises many skills psychiatrists develop in the course of their training. Because of this overlap in skill-set, psychiatrists should be especially well positioned to become important healthcare leaders in the future. Psychiatry residency programs should foster and facilitate these traits as a means to train residents to become leaders. Physicians, in general, are prepared for leadership positions because of their training in the management of patients and clinical teams. However, among physicians, psychiatrists are especially well trained to serve in active leadership roles. In this article, we will identify and discuss the attributes of "great" leaders, draw attention to the unique overlap between these traits and psychiatric expertise, and encourage psychiatrists to seek out and obtain leadership positions.


We calculate the Gibbs potential Gamma (M) of a one-dimensional metal at constant magnetization M to second order in the screened electron-electron interaction U. At zero temperature we find that Gamma (M) contains non-analytic corrections proportional to M^2 \ln | M| and | M |^3, implying that a possible paramagnetic-ferromagnetic quantum phase transition in one-dimensional metals must be first order.


This research paper aims at figuring out the way in which the world perceives the Islamophobic incidents. Such a global perception can be obtained from employing a kind of pervasive discourse that is emitted from global institutions and directed to the world in general. Thus, the conducted linguistic evaluation has targeted the news reports as a kind of global media discourse. The linguistic theory employed for language evaluation is Martin and White's (2005) theory of appraisal. Three categories are classified in the appraisal theory: attitude, engagement, and graduation. Attitude is subdivided into effect, judgment, and appreciation; engagement into monogloss and hetergloss, and graduation into force and focus. The methodology works on three variables in the Islamophobic incident: the aggressor, the victim and motive. The orientation of investigation works to identify the attitude of affect directed from the report towards the victim, judgement towards the behavior of the aggressor, and appreciation towards the motive of the incident. The research also identifies the features of these attitudes as being negative or positive, the types (subclassifications), engagement (monogloss or heterogloss), and graduation (force and focus) of the spotted attitudes. The data consists of twelve news reports selected, according to their topic, from three News agencies: BBC, Independent, and Fox News. The analysis has revealed that, contrary to many claims, news reports tend to adopt a neutral stance towards Muslims and NonMuslims. They tend to portray the Islamophobic incidents as close to reality as possible.


The present invention addresses the problem of providing a solid dispersion which has high safety and is capable of ensuring long-term stability by suppressing decrease in the active ingredient content due to oxidation or decomposition of rapamycin or a derivative thereof. The present invention provides a method for producing a solid dispersion that contains rapamycin or a derivative thereof as an active ingredient. This method for producing a solid dispersion comprises: a first step for mixing a first solvent that is a polar protic solvent, a second solvent that is an aprotic solvent, a water-soluble polymer carrier and rapamycin or a derivative thereof, with the ratio of the first solvent being more than 50% by volume relative to the total volume of the first solvent and the second solvent; and a second step for removing the solvents.


Objective Establishing a systematic,standardized and scientific prevention and control of multidrug-resistant seamless management systems could reduce the incidence of multi-drug resistant infections. Method Aim at the operation of the prevention and control of multi-resistant bacteria in all aspects,a prevention and control of multidrug-resistant seamless management system was established. It could Implement a seamless management for focus groups monitoring,antimicrobial application,information transmission,control measures,administrative supervision strictly,forming a unified ensemble. Results The application of prevention and control of multidrug-resistant seamless management system ensured the quality of all aspects of the implementation and reduced the incidence of multi-drug-resistant infections,improved medical staff awareness of prevention and control of multi-resistant bacteria. Conclusion The multi-sectoral,entire and full participation in the prevention and control of multidrug-resistant seamless management can improve the prevention and control of multidrug-resistant management level in our hospital.


Significance Evolution acts on mutations that naturally arise within the genome and are shaped both by intrinsic genomic features and by the cellular environment. We catalog the mutations arising in a heterozygous diploid yeast during passaging in vitro and in the mammalian host. We establish genome-wide mutation rates and reveal that "microscale" changes (base substitutions and short-track recombination events) are the primary drivers of microevolution, although chromosomal-level changes also occur in specific host environments. Our results define mutation hotspots, including those adjoining recombination tracts, and indicate that many mutations are purged from the population due to purifying selection. Together, these data provide a high-resolution picture of how the heterozygous diploid genome of a fungal pathogen undergoes evolution over short time scales. Candida albicans is a heterozygous diploid yeast that is a commensal of the human gastrointestinal tract and a prevalent opportunistic pathogen. Here, whole-genome sequencing was performed on multiple C. albicans isolates passaged both in vitro and in vivo to characterize the complete spectrum of mutations arising in laboratory culture and in the mammalian host. We establish that, independent of culture niche, microevolution is primarily driven by de novo base substitutions and frequent short-tract loss-of-heterozygosity events. An average base-substitution rate of ∼1.2 × 10−10 per base pair per generation was observed in vitro, with higher rates inferred during host infection. Large-scale chromosomal changes were relatively rare, although chromosome 7 trisomies frequently emerged during passaging in a gastrointestinal model and was associated with increased fitness for this niche. Multiple chromosomal features impacted mutational patterns, with mutation rates elevated in repetitive regions, subtelomeric regions, and in gene families encoding cell surface proteins involved in host adhesion. Strikingly, de novo mutation rates were more than 800-fold higher in regions immediately adjacent to emergent loss-of-heterozygosity tracts, indicative of recombination-induced mutagenesis. Furthermore, genomes showed biased patterns of mutations suggestive of extensive purifying selection during passaging. These results reveal how both cell-intrinsic and cell-extrinsic factors influence C. albicans microevolution, and provide a quantitative picture of genome dynamics in this heterozygous diploid species.


The leaf angle distribution is a key parameter in models useful for understanding the forest canopy processes of photosynthesis, evapotranspiration, radiation transmission, and spectral reflectance. Yet, despite the strong sensitivity of many of these models to variability in leaf angle distribution, the difficulty in measuring leaf angle distribution has limited exploration of its species-specific phenology and variation across environmental gradients and often causes it to be one of the most poorly constrained model parameters. Relatively few measurements of leaf inclination angle distributions have been reported for different tree species in literature and databases such as TRY, and various assumptions about leaf angle distribution are often made by modellers.


This article is concerned with a specific phenomenon of the history of translation into Portuguese, the boom of translation of scientific and didactic texts in the turn of the 18th century in Portugal, in which a considerable number of Brazilians were involved. We focus the work of Friar Jose Mariano da Conceicao Veloso, who has lately been referred to as a key figure in the history of sciences and books publishing in Portugal and Brazil. Friar Veloso was translator, editor, and translation coordinator in charge of the work of translators concerned with pragmatic texts in Lisbon. Veloso's involvement with the still incipient editorial industry in Portugal was linked to Portuguese Enlightenment, especially the dissemination of scientific knowledge that could be applied to the progress of the Portuguese kingdom. Clues of Friar Veloso's close connection with the Portuguese official policies are found in the prefaces he wrote for his translations, and they are enough to include him withim a patronage
system that defined the direction his editorial activities would take. Curiously, despite these ties to the authoritarian Portuguese monarchical regime, Friar Veloso's work led to unexpected historical developments, such as the growth of the reading public and the improvement of printing techniques.


In recent years, the People's Republic of China has become a huge centre of manufacture. Many of the products circulating in global markets are manufactured by China. Such products, which reach very big sizes in quantity, can be bought for very fair prices. Involving a range of many different prices and qualities, Chinese products are used by consumers in conscious or unconscious ways. The purpose of this study is to determine the general opinion, attitude and behaviour of consumers regarding Chinese products that are widely used in our day. The influence of the country of origin on buying behaviour is also addressed by the study. For this purpose, a questionnaire was administered to 319 consumers. A frequency percentage analysis was used to assess the data collected, and the t-test, variance analysis and cross tabulation were utilised to study the approach towards Chinese products by the participants according to their characteristics. The results showed that a majority of consumers have a negative attitude against Chinese products, that they do not want to buy these products, and that country of origin has a significant influence on their buying preference.


Traditional measures of optimality in the design involving pedestrians such as building floor plans have focused mainly on geometries such as maximizing space utility and minimizing distance between travel points. However, other important issues such as safety needs to be addressed as accurately as possible. Not only is it impractical to change design after implementation, small inaccuracies can translate to catastrophes during emergency situations. In this paper, we attempt to bring the evaluation a step closer to reality by using emotional agents to simulate the behavior of pedestrians in dangerous situations. The process can be automated by using simulated annealing to find the global optimum in the design space.


We describe motion coding algorithms for use with the arbitrary shaped objects of emerging video coding standards. These algorithms exploit the temporal redundancy of the object shape description under conditions of concentrated diverse motion. In Variable Sized Block Matching (VSBM), the ambiguity of small area matching is reduced by coalescing blocks to yield accurate motion information over larger blocks. The technique is extended to exploit irregularly shaped areas of uniform motion within a small object. This Modified VSBM (MVSBM) can be enhanced by coding areas of identical motion within the spatial structure of the object. This spatial structure itself has temporal redundancy that can be reduced by inter-frame differential coding. For the MPEG-4 test sequences "Stefan" and "Children" the total amount of data required to specify motion shows improvements of 20% and 17% respectively.


Objective To analyse the medical cost of patients with mental disorders under government assistance in Zhejiang Province. Methods Three hundred and thirty-one patients with mental disorders under government assistance were selected from Huzhou Mental Health Center(n=123) and Shaoxing Mental Health Centers(n=208) between 2006 to 2009,and another 331 patients with mental disorders without government assistance were also selected from Huzhou Mental Health Center(n=123) and Shaoxing Mental Health Centers(n=208) between 2006 to 2009.The categories of mental disorders and physical conditions of patients with mental disorders under government assistance were analysed,and daily medical cost was compared between patients with mental disorders under government assistance and those with mental disorders without government assistance. Results The main categories of mental disorders in patients with mental disorders under government assistance in Huzhou and Shaoxing were schizophrenia(67.4%),mental retardation and dementia(16.3%),and mental disorders due to use of alcohol(9.1%).Meanwhile,38.9% of patients with mental disorders under government assistance suffered from physical diseases such as digestive tract diseases(24.5%) and respiratory tract infection(16.9%).Daily medical cost of patients with mental disorders under government assistance was significantly lower than that of patients with mental disorders without government assistance in Shaoxing(P0.05),and the same condition was found in Huzhou(P0.01).Daily medical cost of patients with mental disorders under government assistance complicated with physical diseases was significantly higher than that of patients with mental disorders under government assistance without physical diseases(P0.01).However,there was no significant difference in daily medical cost between patients in Huzhou and those in Shaoxing(P0.05). Conclusion Medical cost of patients with mental disorders under government assistance is much lower than that of patients with mental disorders without government assistance,but it is still relatively higher.Medical cost may be lowered with sufficient government assistance to those needed by reducing hospitalization duration,establishing basic system of medication and treatment,and conducting regular free drug administration and follow up.


The natural abundance of nitrogen (N) stable isotopes (dN) has the potential to enhance our understanding of the ecosystem N cycle at large spatial scales. However, vegetation and soil dN patterns along climatic and edaphic gradients have not yet been fully understood, particularly for highaltitude ecosystems. Here we determined vegetation and soil dN in alpine grasslands on the Tibetan Plateau by conducting four consecutive regional surveys during 2001–2004, and then examined their relationships with both climatic and edaphic variables. Our results showed that both vegetation and soil N in Tibetan alpine grasslands were more N-enriched than global averages. Vegetation dN did not exhibit any significant trend along the temperature gradient, but decreased significantly with an increase in precipitation amount. In contrast, soil dN did not vary with either mean annual temperature or precipitation. Our results also indicated that soil dN exhibited a slight increase with clay content, but decreased with soil carbon:nitrogen ratio. A general linear model analysis revealed that variations in vegetation dN were dominantly determined by climatic variables, whereas soil dN was related to edaphic variables. These results provide clues for potential climatic and edaphic regulations on ecosystem N cycle in these high-altitude regions.


In November 2000, heavy rains in Slovenia triggered numerous slope processes. Among the largest were the landslide and debris flow in Log pod Mangartom in western Slovenia. This paper describes the main geographical, geological, and geomechanical features of the debris flow, detailing its causes and describing the consequences. The facts presented in the article demonstrate that intensive geomorphic processes are relatively frequent phenomena and are an important factor in the transformation of the surface in alpine regions.


This study has the objective of this research is to 1) develop a Skill Training Package Health Education subject. First aid and transported the patient safely for The first year of secondary school students Samkouk school under Provincial Administrative Organization Pathum Thani efficiency of 80/80. and 2) skill Training Package Development, Health Education of students about first aid and moving patients safely. The students have higher achievement than the previous. The samples the first year of secondary school students Samkouk school under Provincial Administrative Organization Pathum Thani second semester of academic year 2558 amounted to 32 people. The instrument used in the research are: 1) Plan a group learning about health and physical education. First aid and moving patients safely using Learning Cycle (5ES) for the first year of secondary school students 2) Assessment Skill Training Package with 12 points and 3) test achievement is a multiple choice of four options. Select 15 items. The statistics used in the analysis were mean, standard deviation, percent, and the t-test. The results showed that 1. Skill Training Package Health Education subject. First aid and moving patients safely. For students at 1 Samkouk school under Provincial Administrative Organization Pathum Thani developed effective 88.35 / 86.86 higher than 80/80. 2. Skill Training Package Health Education of students about first aid and moving patients safely. Student achievement average score of 13.71 out of 15 points. 83.54 percent higher than the previous.


Abstract The aim of our research was to investigate the detergent content and several micro and macro elements in greywater samples, a necessary step in determining the water quality for the further reuse of the greywater. We determined the anionic detergent content of synthetic greywater with a two-phased titration method prepared in laboratory conditions. The current study leads to a new suggestion for a more accurate and reliable titrimetric method for determination of anionic detergent content of synthetic greywater samples. Following these investigations, we also examined the metal content of synthetic bath water. We wanted to highlight how detergents in greywater influence the micro and macro element content of the given synthetic bath water samples.


This thesis concerns the mediation of history in a public arena in society, namely in historical exhibitions in museums. The foci of the thesis are exhibitions on migration history, cultural encounters, "Us" and "the Others", and in particular how relations based on the principles of class, gender and ethnicity are mediated. The research concerns two exhibitions – "Afrikafararna" (The Travellers to Africa) and "Kongospar" (Traces of Congo).In this thesis museums are viewed as arenas for public education and meaning-making. It explores how the historical contents as well as the forms of mediation in the exhibitions correspond to the task of promoting democracy that has been assigned to Swedish museums. This task is expressed in the intentions of the respective museums, in the general policies on culture and also in the policy documents for schools. Therefore the thesis also explores how pupils and teachers understand the mediation of history and use the museum as a source for learning.Exhibitions are regarded in this thesis as mediation processes of history. Three distinct phases can be seen in this process – the phase of production, the phase of mediation and the phase of reception. People connected to the different phases, such as curators, producers, museum educators, and pupils, have been interviewed. These interviews show how conditions, convictions and scope for action influence how the stories of migration and cultural encounters are told and understood. The contents of the exhibitions are analysed from a perspective of class, gender and ethnicity. Furthermore, the limitations and possibilities for the visitors to intensify their historical consciousness are discussed.The study shows how economic conditions and access to historical source material influence the way history is mediated, but also, and to a very large extent, convictions on pedagogy and concepts of history among museum staff. The latter two are determining factors when it is made clear that the way the historical source material is used results in the fact that history is mediated in a way that does not correspond to the intentions and goals to promote democratic values, such as equality, and active democratic readiness for action.The study shows that the exhibitions in question mediate patterns of subordination and asymmetrical relations between women and men and between Swedes/Scandinavians and Africans in their mediation of history. There are sometimes very distinct lines between "Us" and "the Others". One of the exhibitions offers more space for individual meaning-making and reflection than the other, however, because of its problematization of the occurrence of African artefacts in Scandinavia and because there are more stories and more voices in the exhibition.The interviews with teachers and pupils show that the visits to the exhibitions are often isolated events that are rarely incorporated into the students' education in a prolonged theme or perspective. Several students uncritically accepted the mediation in the exhibition, others were provoked and challenged, but the students had little opportunity to discuss these experiences in either the museum or in school. In summing up, several of the results of the analysis show that the mediation of history in the exhibitions cannot be described as corresponding to the demands of a democratic conception of education.


. We find all connected graphs in which any two distinct vertices have exactly two common neighbors, thus solving a problem by B. Zelinka.


Application of genome editing have garnered a lot of attention in the scientific world. Its ability to make permanent and precise modification or 'edits' in the genomic DNA sequences have open up the possibility of probing the functionality of genes and correcting abnormal genes to treat genetic diseases. The CRISPR/Cas9 which was adapted from Type II bacterial adaptive immune system is the most applied genome editing system due to the ease and efficiency of the system in customising the nucleases needed in editing the targeted sequences. However, the downside of this system is the high frequency of 'off-target' editing caused by the nature of the Cas9 protein that can tolerate mismatches between customised nucleases; sgRNA, and the genomic sequences. Despite the set-back, researchers continue applying CRISPR/Cas9 system to edit the genome by minimising the frequency of 'off-target' edits. Application of the improved system had successfully produced numerous results in the initial treatment of genetic diseases such as cystic fibrosis, β-thalassemia, and Duchenne Muscular Dystrophy. The fast-paced development and improvement made to this system will continue to be utilised by the researchers around the world for the treatment of human diseases, a progress much needed and awaited. Please download the full paper by clicking on the PDF file below...


An 8 year old girl with Alagille's syndrome who developed dystonia secondary to manganese toxicity is reported from the Pediatric Department, Hershey Medical Center, Hershey, PA.


This project explores the use of hybrid clustering technique for lossless compression method for Hyperspectral images. It is based on the joint use of fuzzy c means and nearest neighbor algorithms. In this method, linear prediction is performed using coefficients optimized for each spectral cluster separately. The difference between the prediction and original values is entropy coded using an adaptive range coder for each cluster. The result shows that this method has lower bit-per-pixel value. It is an extension to the existing lossless compression algorithm. Better partitioning of data is achieved. The technique starts with the fuzzy c means algorithm, performed as the first stage for an adequately high number of centroids and continues with the nearest neighbour algorithm executed for the clusters obtained in the first stage, as the set of initial objects to be merged for relatively complex shapes.


We studied how frequently patients with malignant melanoma have specific antibyto cell surface antigens of cultured autologous melanoma cells as demonstrated by mixed hemadsorption assays. Of 35 patients studied over periods ranging from 1 to 36 months with Stage II, IIIand IV disease, two showed consistent and high titered reactivity against autologous melanoma cells, two showed less consistent and intermediate reactivity, seven showed sporatic, low titered reactivity, and the remainder were consistently negative. A detailed analysis was carried out with the sera of one patient with sufficiently high titer against autologous melanoma cells. By direct tests and by absorption analysis with a variety of melanoma and nonmelanoma cell lines which included autologous fibroblasts, the antigen could not be demonstrated on any cell type other than the autologous melanoma. Considerable attention has been focused on the question of whether melanoma cells are marked by distinctive surface antigens. An array of techniques measuring humoral (1-9) and cellular immunity (10, 11) has been applied to the antigens of melanoma. Both individually specific antigens unique for each melanoma (1, 4-6, 9) as well as common antigens shared by several melanomas have been reported (2, 3, 8). Interpretation of these findings is commonly limited by the handicaps confronting human cancer immunologists in their effort to establish the specificity and significance of in vitro reactions. In experimental systems, the availability of inbred strains permitted the transplantation studies that established the existence of distinctive surface antigens in tumors. The serological definition of these antigens in the mouse and rat has also depended on inbred populations to provide the necessary reagents-antisera prepared by hyperimmunization with tumor cells, reference tumor cell lines maintained by transplantation, and normal cells of known antigenic composition. In the absence of these advantages, the serologist studying human cancer is attempting to evolve techniques and approaches that come to grips with the issue of cancer specificity. The present report illustrates the way our laboratory is seeking evidence for melanoma-distinctive surface antigens. In these studies, we have stressed three features: (i) autologous reactions-to eliminate the contributions of antibodies to histocompatibility antigens; (ii) cultured melanomia cells -to provide target cells that can be repeatedly tested; and (iii) absorption tests-to establish specificity by determining the occurrence of antigen on a range of normal and malignant tissues. MATERIALS AND METHODS Tissue culture Melanoma Cells. Sterile tumor specimens were dissected free of adherent normal tissue and were finely minced in Earle's balanced salt solution. The resulting cell suspensions were washed three times in Earle's bajanced salt solution and resuspended in complete medium consisting of Eagle's minimum essential medium containing 1% nonessential amino acids, and. supplemented with 2 mM glutamine, 100 international units/ ml of penicillin, and 100 ,ug/ml of streptomycin. Fetal calf serum (FCS) was included at a final concentration of 20% for primary cultures and 10% for more advanced cultures. Cultures were passed when confluent, at 7to 10-day intervals, by harvesting with 0.05% crystallized trypsin (Tryptar 250,000 units per vial, Armour Pharmaceutical Co.) for early cultures or with 0.01% trypsin (Bacto Trypsin, Difco Laboratories) for established cultures. Details concerning the melanoma lines used in this study will be published elsewhere. Successful cultures have been initiated from approximately 30% of all melanoma specimens submitted for tissue culture. Cultures were examined repeatedly for mycoplasma, fungi, and bacteria; contaminated cultures were discarded. Skin Fibroblasts. Normal fibroblasts were obtained from skin biopsies which were trimmed of subcutaneous fat and minced. The fragments were placed in culture flasks in complete medium with 10% FCS until sheets of fibroblasts were obtained. Fibroblasts were harvested with 0.01% trypsin, transferred to new flasks, and then passaged in a manner comparable to melanoma cell lines. Other Cell Lines. The following cell lines were also used: Me Wo, melanoma (11); SK-Mel-1, melanoma-suspension culture (12); RPMI-7931, melanoma originated by G. Moore at Roswell Park Memorial Institute; J-82, bladder carcinoma (13); T-24, bladder carcinoma (14); SK-L-7, lymphoblast suspension culture (15); and SK-RC-1 and SK-RC-4, two lines derived from renal carcinoma by H. Shiku of this Institute. Serological procedures Mixed Hemadsorption Assay. Mixed hemadsorption (MHA) was performed by the method of Espmark and Fagreus (16) as modified by Metzgar and Oleinik (17). Antisera prepared in monkey and baboon against sheep red blood cells were generously provided by A. Espmark of the National Bacteriological Laboratory, Stockholm, Sweden and G. Giraldo of this Institute. Goat anti-human immunoglobulin serum was purchased from Meloy Laboratories. Polyvalent anti-HLA serum was a gift of C. Whitsett of this Institute. Cultured cells were harvested, washed, and distributed to the wells (1000 cells per well) of 3040 microtest II plates (Falcon Plastics, Oxnard, Calif.) and the plates were incubated at 370 in a CO2 incubator. Multiple plates were prepared for each test .and examined in MHA assays at several different time intervals 3278 Abbreviations: FCS, fetal calf serum; MHA, mixed hemadsorption; Pi/NaCl, phosphate-buffered saline. * This is paper no. I in a series. D ow nl oa de d by g ue st o n N ov em be r 21 , 2 02 1 Proc. Nati. Acad. Scd. USA 73 (1976) 3279 Table 1. Summary of serological results on autologous melanoma cell lines


The electrocardiogram (ECG) is the recording of the electrical potential of heart versus time. The analysis of ECG signal has great importance in the detection of cardiac abnormalities. The electrocardiographic signals are often contaminated by noise from diverse sources. Noises that commonly disturb the basic electrocardiogram are power line interference, instrumentation noise, external electromagnetic field interference, noise due to random body movements and respirational movements. These noises can be classified according to their frequency content. It is essential to reduce these disturbances in ECG signal to improve accuracy and reliability. Proposed research works offers ECG signal classification system uses Principal Component Analysis (PCA) technique to reduce the dimensionality of test signal. Discrete Wavelet Transform is used for feature extraction. Spectral flatness is another feature for the spectrum of ECG. This process helps in enhancing the classification accuracy. Classification is done using Neural Network classifier.


Melanoma can prove fatal if not diagnosed at early stage. Computer aided identification of diseases can equip normal people in performing a screening test of diseases. The accurate lesion segmentation plays a crucial role in correct diagnosis of skin diseases. This work proposes a skin lesion segmentation method using statistical analysis and bit plane slicing. Hole filling operation is competent enough to sufficiently reject the noisy pixels from the finally segmented image. The results of skin lesion segmentation obtained from the proposed algorithm has been compared with the annotated images available with the database. The results arepresented in form of overlapping score and correlation coefficient. An average overlapping score and correlation coefficient of 91.59% and 92.07%, respectively, is obtained from the proposed algorithm. Also, an image based performance analysis of segmented lesion has been done and an average sensitivity of 94.33% has been achieved. The results are convincing and suggests that the proposed work can be used for some real-time application.


Animal agriculture exerts the significant roles for economic income increase of farmers and efficient agricultural production,which resulted a steady increase of animal production value.The developing strategies and measures in the future animal husbandry in Huzhu county were suggested based on the full discussion of current situation and existing issues to provide the references for the exuberant,sustainable and steady development of animal husbandry in Huzhu county.


Background: Ketogenic diet-induced weight loss before bariatric surgery (BS) has beneficial effects on the reduction in the liver volume, metabolic profile, and intra- and post-operative complications. However, these beneficial effects can be limited by poor dietary adherence. A potential solution in patients showing a poor adherence in following the prescribed diet could be represented by enteral nutrition strategies. To date, no studies describe the protocol to use for the efficacy and the safety of pre-operative enteral ketogenic nutrition-based dietary protocols in terms of weight reduction, metabolic efficacy, and safety in patients with obesity scheduled for BS. Aims and scope: To assess the clinical impact, efficacy, and safety of ketogenic nutrition enteral protein (NEP) vs. nutritional enteral hypocaloric (NEI) protocols on patients with obesity candidate to BS. Patients and methods: 31 NEP were compared to 29 NEI patients through a 1:1 randomization. The body weight (BW), body mass index (BMI), waist circumference (WC), hip circumference (HC), and neck circumference (NC) were assessed at the baseline and at the 4-week follow-up. Furthermore, clinical parameters were assessed by blood tests, and patients were asked daily to report any side effects, using a self-administered questionnaire. Results: Compared to the baseline, the BW, BMI, WC, HC, and NC were significantly reduced in both groups studied (p < 0.001). However, we did not find any significative difference between the NEP and NEI groups in terms of weight loss (p = 0.559), BMI (p= 0.383), WC (p = 0.779), and HC (p = 0.559), while a statistically significant difference was found in terms of the NC (NEP, −7.1% vs. NEI, −4%, p = 0.011). Furthermore, we found a significant amelioration of the general clinical status in both groups. However, a statistically significant difference was found in terms of glycemia (NEP, −16% vs. NEI, −8.5%, p < 0.001), insulin (NEP, −49.6% vs. NEI, −17.8%, p < 0.0028), HOMA index (NEP, −57.7% vs. NEI, −24.9%, p < 0.001), total cholesterol (NEP, −24.3% vs. NEI, −2.8%, p < 0.001), low-density lipoprotein (NEP, −30.9% vs. NEI, 1.96%, p < 0.001), apolipoprotein A1 (NEP, −24.2% vs. NEI, −7%, p < 0.001), and apolipoprotein B (NEP, −23.1% vs. NEI, −2.3%, p < 0.001), whereas we did not find any significative difference between the NEP and NEI groups in terms of aortomesenteric fat thickness (p = 0.332), triglyceride levels (p = 0.534), degree of steatosis (p = 0.616), and left hepatic lobe volume (p = 0.264). Furthermore, the NEP and NEI treatments were well tolerated, and no major side effects were registered. Conclusions: Enteral feeding is an effective and safe treatment before BS, with NEP leading to better clinical results than NEI on the glycemic and lipid profiles. Further and larger randomized clinical trials are needed to confirm these preliminary data.


The paper makes a deeply and systematic analysis of the principle about voice communication on network, and explains voice collection, compress and decompress, transmission and so on. It elaborates on the process about the Delphi software development and gives a simple instance of the voice communication.


This study included the test of Antimicrobial activity for two types extracts, the first is effect of aqueous, alcoholic, fresh juice and powder ginger extract .The second is the aqueous and alcoholic extract of Altbek grain on sex bacterial species: Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pneumonia, Proteus mirabilis, Escherichia coli, Klebsiella pneumonia and 3 fungal species belonging to the genus Candida: Candida albicans, Candida krusei, Candida glabrata . The results showed that both the aqueous and alcoholic for  genger have high inhibited activity against p.mirabilis comparison all five tested antibiotics ,Also have the aqueous extract of ginger  high activity against K .pneumonia when compared to all Antibiotics used in the study, either  powder extract of genger have high inhibited activity against only P.aeruginosa while not showed any effective inhibition against bacterial and fungal species, also showed effective inhibition for alcoholic extract of genger against all fungal species, While not showed any effective inhibition for aqueous, juice and powder extract against fungal species. The study showed the aqueous and alcoholic Altbek grain have high effective activity against S.aureus comparison to  Antibiotics: Cefotaxim, Norfloxacin and moderate effective when compared to Antibiotics: Amikacin, Ciprofloxacin, Augmentin, The aqueous and alcoholic genger extract have highly effective inhibition against S.pneumonia compared of Antibiotics: Norfloxacin, Augmentin, Cefotaxim and medium effective compared with Antibiotics: Amikacin, Ciprofloxacin, and did not appear any effective inhibition against all fungal species.


The cytology study is effective and reliable technique in intraoperative consultation. This study was performed to evaluate the accuracy of the cytology study in intraoperative consultation of the breast lesions. 125 specimens of the breast lesions were examined and studied in Imam Khomeini Hospital during the years 1998-99. The sensitivity, specificity and accuracy for cytological method were 87.5% , 95%, 90.5% and for the frozen section 92.4%, 100% and 95.4% respectively. The false positive reports were 2% in the cytology technique and the most important source of error and false postivie reports was fibroadenoma in this method. By reviewing the results. It could be concluded that combination of these two techniques is beneficial and more reliable in intraoperative consultation resports of the breast lesions


Mysore is a third most populous city in Karnataka, provides shelter for diversified population with
different socio-economic standards. It has rich, vibrant history and heritage, attracting good number of
tourists every day. People from different parts of India and the world would like to reside in Mysore city
and expecting good and clean environment around the year. To record the municipal solid waste produced
from different residential houses, 18 wards were selected randomly and 144 residents (40% male and 60%
female) were met personally during January to April, 2018. The municipal solid waste origin, source,
production, collection, storage, isolation, transportation and disposal were collected along with the status
of respondents by using pre-tested questionnaire. The bio-degradable waste from 18 vegetables, 11 fruits,
seven kitchen items and 14 paper types and non-biodegradable waste from 29 plastic items, 15 metals and
14 electronic items appeared at every residential house. Quantity of municipal solid waste recorded from
edible and non-edible items varied considerably. Moreover, the quantity of municipal solid waste
produced from nuclear and composite families varied considerably. However, 3.8 and 17.5% respectively
the nuclear and composite families didn't provide the information about municipal waste produced per
day. However, the daily using few domestic commodities made with different raw materials such as
plastic, iron, woolen, cotton, rubber and paper etc, were difficult to isolate separately as edible or nonedible
waste which were commonly appeared as waste every day at residential houses. Overall, eight items
such as three from edible items (i.e., vegetables, fruits and kitchen), five from non-edible items (i.e.,
plastic, paper, metal, electronic and others) which contributed 96.9% non-edible items and 3.1% edible
items recorded as municipal solid waste at residential houses in Mysore. Despite the clean city status three
times, Mysore is still experiencing hardships to manage municipal solid waste and it demands regular
survey and solid waste analysis to be conducted to develop strategies to control waste and maintain good
environment amidst clean cities.


1. Mass 25 BB's of each brand (store in each order). 2. Shoot them at the target/target paper, 25 feet away. 3. Measure distance from center. 4. Repeat steps 2-3, 2 more times; 3 times at 50 feet and 3 times for 75 feet. Results Excell was the lightest BB, 0.1937g average mass, as well as the one with the most accuracy. It's standard deviation from the average distance from center of the target was lowest. It was also the most consistent in mass, +/-0.00196g. Conclusions/Discussion Excell was most accurate and had the lowest average density meaning that mass/density affects accuracy.


OBJECTIVE Hepatic steatosis is strongly associated with insulin resistance, but a causal role has not been established. In ob/ob mice, sterol regulatory element binding protein 1 (SREBP1) mediates the induction of steatosis by upregulating target genes, including glycerol-3-phosphate acyltransferase-1 (Gpat1), which catalyzes the first and committed step in the pathway of glycerolipid synthesis. We asked whether ob/ob mice lacking Gpat1 would have reduced hepatic steatosis and improved insulin sensitivity. RESEARCH DESIGN AND METHODS Hepatic lipids, insulin sensitivity, and hepatic insulin signaling were compared in lean (Lep+/?), lean-Gpat1−/−, ob/ob (Lepob/ob), and ob/ob-Gpat1−/− mice. RESULTS Compared with ob/ob mice, the lack of Gpat1 in ob/ob mice reduced hepatic triacylglycerol (TAG) and diacylglycerol (DAG) content 59 and 74%, respectively, but increased acyl-CoA levels. Despite the reduction in hepatic lipids, fasting glucose and insulin concentrations did not improve, and insulin tolerance remained impaired. In both ob/ob and ob/ob-Gpat1−/− mice, insulin resistance was accompanied by elevated hepatic protein kinase C-ε activation and blunted insulin-stimulated Akt activation. CONCLUSIONS These results suggest that decreasing hepatic steatosis alone does not improve insulin resistance, and that factors other than increased hepatic DAG and TAG contribute to hepatic insulin resistance in this genetically obese model. They also show that the SREBP1-mediated induction of hepatic steatosis in ob/ob mice requires Gpat1.


ABSTRACT Wehave used a computer-driven scanningandimage-processing system to identify a panel of30cDNAclones whosepatternofexpression in individual biopsyspeci-mensdistinguishes theflat, normal-appearing colonic mucosaofpatients in twogeneticgroupsathigh riskfordevelopmentof colorectal cancer from that of normal colonic mucosa inlow-risk individuals. Thetwo high-risk groups, faialade-nomatouspolyposisandhereditarynonpolyposiscoloncancer,areindistinguishable basedonthepatternofexpressionofthe 30 selected clones. Thissuggests thatthe extensive plelotropiceffects oftheinheritedloci, whichmayplay an importantrole in the mechanism of increased risk and early onset of the disease, are similar in these populations. Patients withfamilialadenomatouspolyposis(FAP)inherit a defectivegene(APC,adenomatouspolyposiscoli)located on chromosome 5q21 predisposing them for development ofmultiple benign colonic adenomasthat are at very high riskforprogression to colonic cancer (1, 2). Thegenetic events inprogression from the earliest adenomas to carcinoma havebeen studied in detail in both


n 1901 Harper's Bazaar asked the question, "Have Women a Sense of Humor?" (Coquelin 67). More than one hundred years later, Vanity Fair published an article explaining "Why Women Aren't Funny" (Hitchens 54). These articles are part of a larger debate about women's capacity to engage in and appreciate humor that has existed for many years and represent traces of a long-standing prejudice in American culture against women performing comedy, a prejudice that has affected women's comic expression in every form and forum. Public debates about whether women have a sense of humor and the nature of women's humor date to at least the nineteenth century and clearly continue to this day. Countless writers and critics have argued that femininity and a sense of humor are mutually exclusive and that women's "natural" inclination toward emotion and sensitivity has left them incapable of possessing a quality—humor—that many feel is dependent on "masculine" traits such as intellect and aggressiveness. Women, the argument goes, are far too refined and delicate to be funny. The True Woman, the feminine ideal for much of the late nineteenth century, was known for her morality, passivity, and spirituality, not for her ability to tell a joke. But just as women in the first decades of the twentieth century challenged assumptions about femininity established with the True Woman, female comedians during this time challenged the notion that women were inherently unfunny. Comediennes in early twentieth-century entertainments such as vaudeville and silent film were performing at a time when debates about women and comedy were at their most heated and when the very concepts of "woman" and "femininity" were undergoing massive transformation. Because of the pervasive belief that comedy was inappropriate for women, female comics were much more liable than other performers to be seen I "Have Women a Sense of Humor?"


Purpose: to study anatomical and physiological features of the soft palate in patients with rhonchopathy and obstructive sleep apnea (OSA) syndrome so as to minimize damage to tissue structures during laser uvulopalatoplasty.Material and methods. Five hundred twenty-three patients with rhonchopathy and OSA syndrome were examined using the index technique for determining neck circumference-height ratio (NHR), pharyngoscopy and endoscopy of the oral and pharyngeal cavities.Results. Obstructive sleep apnea syndrome is more often met in patients having rhonchopathy and the brachymorphic and mesomorphic type of their neck. The researchers have found a clear dependence between the increase in the number of patients having rhonchopathy and moderate and severe obstructive sleep apnea syndrome and the increase of soft palate hypertrophy combined with ptosis. A cone-shaped depression on the anterior surface of the soft palate was noted in 80-90 % of patients with normal weight (body mass index < 25); in 40–60 % of patients with grade I obesity (body mass index – 30–34.9); in 10–15 % of patients with grade II obesity (body mass index – 35–39,9); in patients with grade IIIobesity (body mass index > 40) there were no any depression in the soft palate. Patients with uncomplicated snoring have a thick area in the forma pillow at the back of their soft palate sized 1 × 0.5 × 0.5 cm, while in patients with severe OSA syndrome this «pillow» is up to 2 × 1.5 × 1 cm.Conclusion. The effectiveness of laser uvulopalatoplasty depends not only on the adequate choice of main parameters for laser irradiation, but also on the careful consideration of anatomical and functional features of the soft palate in each operated patient with rhonchopathy and obstructive sleep apnea syndrome.


In the last three decades role of pharmacist has changed dramatically. Presently, the pharmacists are becoming more patient oriented than product oriented. Patient counseling by pharmacist deals with providing information to the patients regarding the diseases, medications and lifestyle modifications. In diabetes, self management and patient adherence to the prescribed medication and lifestyle modifications is very essential and pharmacist can play an important role in counseling. A study was carried out to assess the influence of pharmacist provided patient counseling on patients' perception about quality of life in type 2 diabetes. 70 type-2 diabetes mellitus patients (48 males and 22 female) were enrolled and randomized into test and control groups. Mean capillary blood glucose levels were decreased in test group where as non-significant increase of capillary blood glucose levels was observed in the control group patients. Pharmacist provided patient counseling might be considered as an important element in implementing the disease management program.


To study the function of the superior head of the human lateral pterygoid muscle (SLpt) we have divised an inserting method with resin splint. The method is based on the anatomical mean value. The aim of this study was to explain and discuss the method.Using this method we have recorded EMGs of SLpt 40 times in 29 subjects.The results were as follows:1. Accidents like hematoma or bleeding didn't occur.2. 90% of subjects could be placed EMG electrodes correctly only once.3. We could easily record reproducible EMG of SLpt.From these findings it is suggested that this method is usefull to investigate the fundamental property of SLpt and to diagnose the patients with craniomandibular dysfunction.


We present H-band observations of gravitationally lensed QSO host galaxies obtained with NICMOS on HST as part of the CfA-Arizona-Gravitational-Lens-Survey (CASTLES). The detections are greatly facilitated by the lensing magnification in these systems; we find that most hosts of radio-quiet QSOs (RQQ) at z~2 are of modest luminosity (L<L_*). They are 2-5 times fainter than the hosts of radio-loud QSOs at the same epoch. Compared to low redshifts, RQQ hosts at z~2 also support higher nuclear luminosities at given stellar host mass. This suggests that the supermassive black holes at their centers grew faster at early epochs than the stellar body of their surrounding host galaxies.


This paper describes a smart monitoring gate-less system by using RFID technologies that had been implemented in Universiti Malaysia Perlis. The objective of this system is to ease the security to monitoring the cars-in and cars-out from the main gate manually. The security can check and manage the staff by system management in PC. This smart monitoring gate-less system consists of RFID tag antenna that be attached at sticker's staff, RFID reader and software management application. For the software management application, this project used LabView as a simulation tool for the data acquisition. The data which contains of name, staff number, number plate, car model and color will be stored in cloud-based storage. All the information data can be accessed from any location because the security management can access it through mobile. This project will present how efficient the vehicle control application on campus which enable the security guard to check a car sticker either legal or illegal in a shortest way.


We present the first clustering measurement of Strong Blended Lyman α (SBLA) absorption systems by measuring their cross-correlation with the Lyman α forest. SBLAs are a new population of absorbers detected within the Lyman α forest. We find a bias of 2.329 ± 0.057, consistent with that of Damped Lyman α absorbers (DLAs). For DLAs, we recover a bias of 2.331 ± 0.057 larger than previously reported (Pérez-Ráfols et al. 2018b). We also find a redshift space distortion parameter β = 0.417 ± 0.010, also consistent with the recovered value for DLAs (β = 0.416 ± 0.010). This is consistent with SBLA and DLA systems tracing different portions of the circumgalactic medium of a broadly common population of galaxies. Given these common clustering properties, we combined them to perform a cross-correlation of galaxies in absorption with the Lyα forest. We find that the BAO scale uncertainty of this new measurement is 1.75 × that of Lyα auto-correlation and 1.6 × that of the quasar cross-correlation with the Lyα forest. We note that the current preferred metal contamination model for fitting the correlation functions with respect to the Lyα forest is not realistic enough for SBLA systems, likely due to their status as high redshift precision sites of high metal enrichment. Mock spectra including SBLA systems and their associated metal absorption are required to understand this sample fully. We conclude that SBLAs have the potential to complement the standard Lyα cosmological analyses in future surveys.


While Holmes Rolston was against anthropocentrism and biocentrism,he brought forward ecocentrism which reflects the role of human and the relationship between human and the nature.In the theory of natural value,Rolston defined human with "double dimensions",confirming the importance of human in the nature and the overriding place of ecosystem as well.Ecocentrism serves as an important guideline for the advocation of harmonious development of human and nature and the construction of a harmonious socialist society.


South-Asia contributes substantially to the number of gastrointestinal (GI) infections occurring globally in humans, including Ascaris, Trichuris and hookworms, the so called soil-transmitted helminths (STH). There is presumptive evidence that animals such as dogs and pigs contribute to the epidemiology of these parasites. In southern India, the role of these animals as reservoir for most GI parasites, especially the human STH still remains unclear. The main objective of this pilot study was to assess parasitic infections in both humans and pigs in Vellore district (southern India).


During the implementation of active prophylactic measures of pharmacological and nonpharmacological nature in unorganized population for 2 yrs with respect to 5 CHD risk factors the authors observed a stable decrease in the percentage of persons with high arterial pressure (by 10%) and smoking (by 9.7%). Intense physical training decreased excess body mass resulting in a decrease in the mean level of arterial pressure, the level of cholesterol in the blood and an increase in physical working capacity.


: An alternative explanation of ostensible clairvoyance has been that percipien~s precognize the future state of their brain when they receive feedback about the target order. Older studies of pure clairvoyance, where this possibility is eliminated, suggest that clairvoyance exists, but these studies have some method ological problems. In this investigation, a computer tested clairvoyance (guessing numbers 1-10) with and without feedback. Totals were rec()rded in the pure clair voyance condition only, so there could be no future inspection of target orders by anyone. Percipients with no previous history of success in laboratory psi tasks showed no results, but three talented percipients showed success in the pure clairvoyance task in accordance with their known beliefs, viz., significant psi-hitting by the percipient who accepted pure clairvoyance and significant psi-missing by the two who did not 'accept it.


The Internet of Things (IoT) provides applications and services that would otherwise not be possible. However, the open nature of IoT makes it vulnerable to cybersecurity threats. Especially, identity spoofing attacks, where an adversary passively listens to the existing radio communications and then mimic the identity of legitimate devices to conduct malicious activities. Existing solutions employ cryptographic signatures to verify the trustworthiness of received information. In prevalent IoT, secret keys for cryptography can potentially be disclosed and disable the verification mechanism. Noncryptographic device verification is needed to ensure trustworthy IoT. In this article, we propose an enhanced deep learning framework for IoT device identification using physical-layer signals. Specifically, we enable our framework to report unseen IoT devices and introduce the zero-bias layer to deep neural networks to increase robustness and interpretability. We have evaluated the effectiveness of the proposed framework using real data from automatic dependent surveillance-broadcast (ADS-B), an application of IoT in aviation. The proposed framework has the potential to be applied to the accurate identification of IoT devices in a variety of IoT applications and services.


A right and precise intake of nutrients is the key to a healthy life. Nutrients play a major role in the human diet and are responsible for the various cellular and enzymatic processes and growth of the body. One such category of nutrients is the polyunsaturated fatty acids (PUFAs) that our body cannot synthesize; therefore it is essential that these are taken from external sources to replenish our body. The aim of this study was to find out the effect of nitrogen and salinity on PUFAs in Ocimum basilicum, determine the ratio of these PUFAs in some algae and higher plants, and identify the most potent source. It was found that Chlorella vulgaris among the selected algae and Ocimum basilicum among the higher plants studied, gave the omega-6: omega-3 ratios of 1.93:1 and 0.67:1 respectively. Overall, Ocimum basilicum gave the best result among both algae and higher plants.


An adsorption heat exchanger (E), having a plurality of heat exchange channels (10) and a respective suction passage (11) in thermal contact, wherein the adsorbent material (12) is fixed on the inner surface of the channel (11).


raphies (1956 to 1959) by the editor, repertories by Dr. Emanuel Diez of the treaties concluded by Switzerland which entered into force in 1957 and 1958, and reports by Professor Paul Guggenheim on Swiss practice in 1956 and 1957. The latter are very useful supplements to the reporter's well-known Treatise of International Law, with References to the International and Swiss Practice, now available in a German and a French edition and, it is to be hoped, soon also in an English version.


Painting is a work of art with various strokes, textures, and color gradations so that a painting that is synonymous with beauty is created. The various paintings created have characteristics, such as the paintings by Van Gogh, which have tightly arranged strokes, creating a repetitive and patterned impression. This study classifies paintings by Van Gogh or not by using the VGG-19 and ResNet-50 feature extraction methods. The SVM method is used as a classification method with two optimizations, namely random and grid optimization in the linear kernel. The data set used consisted of 124 Van Gogh paintings and 207 paintings by other painters. The use of VGG-19 feature extraction using grid optimization has the best value of 93,28% using the use of random optimization which has a value of 92,89%. The use of ResNet-50 using grid optimization with the best value of 90,28% using the use of random optimization which has a value of 90,15%. The extraction feature of VGG-19 is better than ResNet-50 in paintings by Van Gogh or not.


5592 Background: Survivors of gynecologic cancers may be at risk for cancer-related late-effects, including fatigue, pain, second malignancy risk, and sexual side effects. The Institute of Medicine has recommended survivorship care plans (SCP) for all cancer survivors.

METHODS
A program for creation of SCP, OncoLife, is publicly accessible through OncoLink ( www.oncolink.org ), serving over 3.9 million pages/month to 385,000 unique IP addresses (August 2008). Users responding to 17 queries regarding demographics, diagnosis, and treatment receive comprehensive, individualized guidelines for future care. User data is maintained anonymously and securely, with IRB approval.

RESULTS
From May 2007-November 2008, 3,343 individuals completed OncoLife surveys. Survivors of gynecologic cancers represented 8% (n = 272; 58% ovarian, 24% endometrial, 19% cervical). Median ages at diagnosis of ovarian, endometrial, and cervical cancer were 50, 51, and 35 yrs, respectively, and median current ages 53, 55, and 47. Surgery was undergone by 98% of ovarian, 97% of endometrial, and 81% of cervical cancer survivors, and chemotherapy/ radiotherapy by 91%/12%, 51%/59%, and 67%/67%, respectively. Known genetic syndromes were reported by 13% of ovarian cancer survivors, compared to < 1% of endometrial/ cervix cancer survivors (p = 0.0006). Of all gynecologic cancer survivors, 53% reported being followed by an oncologist, 14% a primary care provider (PCP), and 27% both. Only 7% had received survivorship information previously.

CONCLUSIONS
Most survivors of gynecologic malignancies have undergone multimodality treatment and may particularly benefit from SCP guidelines. Most do not receive follow-up care from both an oncologist and PCP, and few have received survivorship information. Gynecologic cancer survivors appear willing to use this tool; future iterations will focus on further individualization of guidelines, and improving access to underrepresented populations. No significant financial relationships to disclose.


Abstmct- A new entropic measure of interdependence among groups of objects is introduced, and applied to some clustering problems successfully. Most of practical algorithms to carry out clustering tasks are based upon the notion of distance between two objects. For the purpose of taking 'more-than-two-elements correlation' into account, Satosi Watanabe introduced an entropic measure of similarity and cohesion among groups of objects, and proposed a method of interdependence analysis. His method has a number of theoretical merits, but sometimes it does not work. The present paper clarifies the nature of its difficulty, propose a possible modification of the method, and discuss the advantages of new approach by showing examples. Keqwo- pattern recognition, classification, clustering, mutual information, minimum entropy.


We study the relation between sound radiation patterns and the azimuthal-mode bal ance of instability-wave amplitude in a subsonic jet using mid-field and near-field phasedmicrophone arrays. To identify instability waves, we apply a least square optimization method, i.e. a beam-forming algorithm, to pressure signals obtained from a conical micro phone array surrounding the jet from the nozzle exit to the end of the potential core. For the reference solutions, we use eigenfunctions based on linear stability analysis using the turbulent mean-velocity profiles and infer the amplitude of the axisymmetric and first two azimuthal modes associated with the Kelvin—Helmholtz instabilities. Likewise, pressure signals obtained from the mid-field array are decomposed into the azimuthal modes, and the directivity of low-frequency noise, particularly that of coherent sound, is analyzed. The azimuthal mode balances of the instability waves and acoustic waves are then com pared, and the effects of compressibility, jet temperature and nozzle type (i.e. straight and chevron nozzles) are investigated. The results show that the directivity of low-frequency jet noise changes from the quadrupole radiation patterns to highly directive ones as increasing Mach number, while all instability modes are suppressed owing to compressibility without substantially varying the azimuthal-mode balance. The correlation of the azimuthal-mode balance between instability waves and coherent sound is stronger at higher Mach numbers. We also find that the radiation patterns of low-frequency noise change from quadrupoles to dipoles as the temperature increases at a low Mach number.


Sometimes political theorists like to imagine that they are lonely humanists misplaced in social science departments. In fact, political theory was created as part of a political science composed of both humanistic and social-scientific elements. Rather than trying to locate political theory somewhere between the humanities and the social sciences, we should instead dismantle the boundary between the two and create a unified discipline of questioning that embraces both kinds of inquiry.