To investigate the effect of ionizing radiation on p16 gene transcription and protein expression in EL-4 cells in vitro, RT-PCR semi-quantity method was applied to determine the p16mRNA level and immunocytochemistry (ICC) was employed to measure the p16 protein expression. The time-course experiments showed that the p16 mRNA level increased at 2—48h in EL-4 cells, and the p16 protein expression increased significantly in EL-4 cells (p0.01) at 12h after 2.0Gy X-irradiation. The dose-effect experiments showed that the p16mRNA level increased with the dose, and the p16 protein expression increased significantly (p0.01) with the dose in 2.0 - 6.0Gy range. The results suggested that the increase of p16 gene transcription and protein expression in EL-4 cells might play role in G1 arrest induced by ionizing radiation in vitro.


When the bleeding occurs in the blood vessel of large diameter, when the abdominal surgery and endoscopes, a hemostatic clip and a hemostatic clip operation apparatus using the same which can even stop the bleeding of the bleeding site quickly, without covering the entire blood vessel is disclosed. Hemostatic clip operation apparatus according to the present invention the handle portion and a first clamp portion and a first clamp is provided to receive parts to be symmetrical to the closed loop form of the hemostatic clip bent first clamp section for bleeding the bleeding site of the blood vessel as a primary in the second clip portion for clipping the outer periphery of the bleeding bleeding part secondarily by, it is provided to connect the handle portion and the first and second clamp a first index and the second index in association with the handle portion moving operation sequential bleeding and clipping operation portion may include a clamp driving unit for driving. Hemostatic clips, vascular, hemostasis, forceps, closed loop (closed-loop)


AbstractUnderstanding catchability—the fraction of a stock caught by a defined unit of effort—is crucial to using fisheries assessment data to index abundance. We conducted mark–recapture experiments to estimate catchability and evaluate standard boat electrofishing methods for assessing populations of Largemouth Bass Micropterus salmoides. We then used a resampling analysis to test for differences in bass CPUE (fish/h and fish/km) between two high-density reservoirs and one low-density reservoir and among surveys within each reservoir. We compared scenarios using surveys conducted only during (1) the standard time period (mid-April to mid-May) and (2) the entire assessment period (early April to mid-June). We considered the percentage of significant differences in CPUE between the high-density and low-density reservoirs to represent statistical power (i.e., the ability to detect a difference in CPUE when a difference actually exists) and the percentage of significant differences in CPUE between surveys i...


PURPOSE: To provide general accessing function to a rotor vane for more cleanliness by allowing at least part of a rotor vane housing to be moved to a water- intake housing so that the interior of a rotor vane housing is accessible from the outside. CONSTITUTION: A stator vane 76 directed to an axis is provided in the stern direction or the left side of a rotor vane 74 to serve for the straight flow of water generated by the rotor vane 74 during operation. The stator vane 76 is formed on a separable portion 58, extending from around the outside to a center hub, the hub having a bearing for pivotally supporting the rotor vane 74 for rotation. With the rotor vane 74 pivotally supported at the separable portion 58 in this way, the separable portion 58 is separated from the fixed stem portion of a rotor vane housing to expose the rotor vane 74 having a number of vanes. The rotor vane 74 is disconnected from a power output driving shaft 78 connecting a power head to the rotor vane 74 by the separation of the separable portion 58 from the stem portion 56.


The distribution of growth hormone‐releasing hormone‐like peptides (GHRH‐LP) in the central nervous system of the zebrafish was investigated by using immunohistochemical techniques with polyclonal antibodies. ELISAs showed that the antiserum raised against salmon (s)GHRH‐LP recognized both zebrafish GHRH‐LP1 and ‐2, whereas the antiserum raised against carp (c)GHRH‐LP was more sensitive but detected only zebrafish GHRH‐LP1. Neither antiserum detected the true GHRH. Large cells in the nucleus lateralis tuberis were immunoreactive with both antisera, which suggests that they contained zebrafish GHRH‐LP1, but not excluding GHRH‐LP2. Also, immunoreactive fibers, which putatively originated from these hypothalamic neurons, were present in the hypophysis; both antisera detected fibers, although only sGHRH‐LP antiserum stained fibers in the neurointermediate lobe. These fibers may have a neuroendocrine role. Candidates for a role in feeding include several areas in which both antisera labeled cells and fibers, implying a strong reaction for GHRH‐LP1 and possibly GHRH‐LP2. These areas include the isthmus with cells in the secondary gustatory/visceral nucleus, which were also calretinin immunoreactive. Numerous GHRH‐LP‐immunoreactive fibers (also labeled by both antisera) probably originate from the gustatory/visceral nucleus to innervate the ventral area of the telencephalon, preglomerular nuclei, torus lateralis and hypothalamic diffuse nucleus, habenula, torus semicircularis, and dorsolateral funiculus of the spinal cord. Present results in the zebrafish brain suggest involvement of GHRH‐LP in both neuroendocrine and feeding‐associated nervous circuits. The present data on the location of the two GHRH‐LPs are the first clue to the possible functions of these two hormones. J. Comp. Neurol. 513:685–701, 2009. © 2009 Wiley‐Liss, Inc.


This paper develops a model of the joint determination of production, inventories and pricing of a monopolistically competitive durable good.producer. The model gives rise to time-varying markups that interact with the inventory-sales ratio, even with flexible prices. Maximum likelihood estimation with automobile industry data yields plausible parameter estimates and impulse responses. We then apply the model to analyze the impact of the "Cash-for-Clunkers" program, and AƒA'find that the model predicts a negligible production response; essentially all the action is inventories. This leads us to consider evidence of threshold effects that imply a stronger response very far from the steady state. This results in a modest but more plausible production response to the policy--still modest in comparison to the sales impact, but now at least measurable. Even with some production response, the results still provide a cautionary tale for countercyclical policies that rely on stimulating consumer spending. Even an impact on spending need not translate into a comparable impact on employment and output.


Lately, great emphasis has been placed on upholding sustainable development principles with the goal to preserve natural resources and protect the environment in order to ensure successful and undisturbed development of a competitive tourist destination and tourist offer. Ecologically acceptable renewable energy sources play a great role in this process. They also demand greater investments ; however, their long-term use justifies the invested resources. They represent the key guideline of future sustainable development and are one of the basic elements for successful diversification of the Croatian tourist offer in relation to the competing countries, considering the fact that modern tourists have developed ecological awareness and show increased tendency of staying in ecological tourist destinations. The use of renewable energy sources will result in a significant decrease in the use of fossil fuels, the sources of which have been disappearing, and emission of greenhouse gases will be reduced. The greenhouse effect leads to significant climate changes, which pose a direct threat to the tourist offer of the Republic of Croatia as a tourist destination.


Current plans call for an alkaline scrub of actinide-bearing sludges in the Hanford Waste tanks prior to their incorporation in glass waste forms. Though it is assumed that actinides will remain in the sludge phase during this procedure, this assumption is based on insufficient supporting thermodynamic and kinetic data. In this project we will investigate the fundamental chemistry of actinides in strongly alkaline solution and solid phases to strengthen the foundation and identify potential limitations of this approach. We will focus on the characterization of the leaching of actinides from simulated BiPO4, REDOX, and PUREX sludges, the identification of actinide mineral phases in the sludge simulants, and the possible solubilization of actinides by complexation and radiolysis effects. This program will provide new fundamental information on the chemical behavior and speciation of uranium, neptunium, plutonium, and americium in simulated alkaline tank waste sludges and alkali ne scrub liquors. Sludge simulants will be prepared from the appropriate matrix components using published data for guidance. Actinide ions will be introduced in the oxidation states pertinent to process conditions. We will characterize the speciation of the actinides in the sludges using a variety of techniques. In parallel studies, we will address the chemistry of actinide ions in alkaline solutions, principally those containing chelating agents. The third critical element of this research will be to assess the impact of radiolysis on actinide behavior. By correlating actinide speciation in the solid and solution phases with sludge composition, it will be possible to predict conditions favoring mobilization (or immobilization) of actinide ions during sludge washing. The new information will increase predictability of actinide behavior during tank sludge washing, and so contribute to minimization of the volume of high level waste created.


The role of cities in the transformation of society is discussed. The growing importance of cities and their global networks undermine the nation state. This is a reversal of the development of the modern state which, over several centuries, increased its control over its territory and cities. Such changes have generated renewed interest in the Middle Ages. The relations between Medieval cities and territorial states were part of complex and shifting political arrangements, involving urban networks and overlapping claims to authority over territories. The general characteristics of prospective neomedieval political systems are discussed in more detail and applied to the regulatory challenges faced by neoliberalism and the transformation to a circular economy. The shift in the focus of neoliberal policy from the competitiveness of cities to that of metropolitan regions, with diverging urban and provincial interests hampers neomedievalist coordination. The cooperation between urban and provincial interests can however be realised in the transformation from a linear to a more circular economy, where metropolitan regions are well suited to accommodate the diverging aspects and forms of territorial regulation in a neomedievalist manner.


The paper investigates the design of H2 and H∞ controllers for a permanent-magnet synchronous motor drive system without using shaft-position sensor, and presents the field-weakening control algorithm of the drive system. Robust PI, H2 and H∞ control techniques are applied to design servo controllers. A fully digital control system under the vector control framework is constructed for experimentally verifying controller performance. The theoretical development is validated by experimental work. The paper provides a new approach for designing sensorless AC drives using currently available high performance microprocessors.


PURPOSE OF THE STUDY
Use archived public data from Arizona to explore relationships among selected institutional and resident risk and situation-specific factors and complaints and substantiated allegations of various types of mistreatment in assisted living facilities (ALFs).

DESIGN AND METHODS
An exploratory/descriptive 2-group design was used. Facilities in the complaint group were identified from narrative data that appeared suspicious for mistreatment based on definitions for physical, verbal, psychological, medication, sexual abuse, neglect, financial exploitation, and physical restraint. Facilities in the comparison group were those that had no citations or complaints in 2007-2008. Narrative data were content analyzed, and chi-square analysis was used to answer 3 research questions.

RESULTS
The complaint group was comprised of significantly more assisted living centers, large facilities (51-101+), facilities licensed to provide personal care services, and facilities owned by national corporations. Substantiated allegations were significantly more frequent in assisted living centers, facilities with more than 51 beds, and those owned by national corporations. Facility risk factors were related to some types of substantiated mistreatment and not others.

IMPLICATIONS
Findings suggest the need to evaluate use of only unlicensed assistive personnel in facilities, increase oversight of care by professional nurses, rethink the practice of not licensing small facilities, and monitor more closely practices and procedures in facilities operated by national corporations.


This paper provides evidence that shifts in the occupational composition of the U.S. workforce are the most important factor explaining the trend decline in the labor share over the past four decades. Estimates suggest that while there is unitary elasticity between equipment capital and non-routine tasks, equipment capital and routine tasks are highly substitutable. Through the lenses of a general equilibrium model with occupational choice and the estimated production technology, I document that the fall in relative price of equipment capital alone can explain 72 percent of the observed decline in the U.S. labor share. In addition, I find that differences in labor share trends across sectors can be accounted for by varying sensitivities of cost of production to the price of equipment capital.


ADR is an umbrella term for processes, other than judicial determination, in which an impartial person assists those in a dispute to resolve the issues between them. ADR is commonly used as an abbreviation for alternative dispute resolution, but can also be used to mean assisted or appropriate dispute resolution. Some also use the term ADR to include approaches that enable parties to prevent or manage their own disputes without outside assistance. See also PDR.


"Wild morning glory" (Convolvulus sp.) is widely known in the United States and many parts of the Old World as a bad weed. Spots appeared in Utah more than a generation ago. No serious attention was paid to the weed before 1900, except in one or two localities where it had early become troublesome. By 1921, it had become so serious in several counties—notably Sanpete, Millard, Juab, and Davis—as to attract widespread attention. Agronomists believed that it could be controlled by vigorous cultivation, but many farmers and several farmers' organizations insisted that this was inadequate. Meanwhile, a wave of sentiment for spraying with sodium arsenite swept over the most populous parts of the state.


In Lorentz-violating electrodynamics a steady current (and similarly a static charge) generates both static magnetic and electric fields. These induced fields, acting on interfering particles, change the interference pattern. We find that particle interference experiments are sensitive to small Lorentz-violating effects, and thus they can be used to improve current bounds on some Lorentz-violating parameters.


1. Logging device for timber blanks comprising gripping elements (2) for holding a tree trunk, a cutting device (3) for cross-cutting a tree trunk held by the gripping elements (2) and a marking device (10) for applying identification marking on the end the surface of the mechanical cut tree trunk held by the gripping elements (2), characterized in that: - marking device (10) comprises a striking arm (11) equipped with an impact head (12) at its outer free end; ! - marking device (10) comprises an actuating element (30, 30 ', 30' ') for actuating the striking arm (11); and! - striking lever (11) can be rotated about the rotational axis (14) under the action of the actuating element (30, 30 ', 30' ') from the inoperative position to the striking position to thereby allow the striking head (12) strike the end mechanical surface cut tree trunk held by the gripping elements (2) in order to apply the identification marking on said end surface. ! 2. Logging device according to claim 1, characterized in that the actuating element (30, 30 ', 30' ') adapted to act on the striking lever (11) via a lever mechanism (20) which is configured to accelerate the striking arm ( 11) during the final part of the path of the striking arm from an inoperative position to the striking position. ! 3. Logging device according to claim 2, characterized in that the lever mechanism (20) configured to retard


The effect of zeolite containing rock application in dozes 3…24 t/ha on the content of heavy metals in leaves and berries of black currant, raspberry and gooseberry was investigated in the field experiments. As a result of the meliorant application the content of Pb and Ni in berries was decreased on 20…70% depending upon the crop. The specific peculiarities of Zn and Cu uptake in berries and leaves of studied crops were revealed.


The objective of this study is to advance the technology of tunnel excavation by analyzing the application of pneumatic and slurry pipelines for increasing the rate of muck removal from the tunnel face. A computer simulation was used to analyze the cost-performance of the pipeline transportation system. This report discusses the results of a two-phase study on rapid excavation. The first phase aims to model the performance of the proposed transport system so that parametric analyses can be performed to determine the applicability of the system and, the second phase aims to model the cost-performance of the system in which grinding at the face by the tunnel-boring machine is minimized while the cutter wear life is maximized. A crushing circuit is provided for the much to reduce the energy requirements for pipeline transportation, both pneumatically and hydraulically. The pneumatic pipeline provides the necessary extensibility by telescoping pipe to convey the muck from the advancing tunneling machine to the stationary high capacity slurry pipeline for rapid long distance transportation. The system concept is based entirely on commercially available equipment with minimum modifications necessary to adapt it to tunnel geometry. Unit transportation costs for several system designs are also discussed herein. /UMTA/


Cattle are considered as one of the sources of pathogenic E. coli worldwide. The present study was designed to determine the prevalence and identification of the E. coli isolated from rectal swab of apparently healthy cattle in Mymensingh, Bangladesh. A total of 128 rectal swab samples were assessed by cultural, morphological and biochemical examination followed by Polymerase Chain Reaction (PCR) using primers ECO-1 and ECO-2 that are specific for E. coli 16S rRNA gene. Data obtained from this study were analyzed based on the age, sex, breed and management systems of cattle. This study revealed a 75% prevalence of E. coli in the rectal swab of cattle. Higher prevalence was found in female cattle of unorganized farming systems, and in cattle ≥3 years of age. From this study, it may be concluded that, irrespective of age, sex, breed and management system, E. coli is prevailing in the rectal swab of apparently healthy cattle.


Objective:To observe the effect of injection of hyaluric acid sodium into knee joint cavity on knee osseous arthritis. Methods: Injection of hyaluric acid sodium performed in 82 sides of 70 patients with knees osseous arthritis,once a week for 5 weeks. Results: After 3~4 month treatment the superior rate was 60.0% (42 examples), the good 28.6%, moderate 8.6%, and failed 2.8%. The superior and good rate was 88.6%,the effectiveness was 97.2%.No appeared side effect was observed.The lighter symptoms and the earlier treating,the more effects the drug showed.Conclusion: Injection of transparency sour sodium inoculation fluid into joint cavity could effectively alleviate pain and swelling of joint with improvement function。 It may be a safe and effective method for treatment of knee osseous arthritis.


Background  Eosinophilic bronchitis is a recently described, relatively benign condition in humans that is characterized by a corticosteroid‐responsive chronic cough and sputum eosinophilia without the abnormalities of airway function seen in asthma. The exact cause of this condition is currently unknown, however has been associated with various occupational exposures in humans. It has also been reported to progress to irreversible airway obstruction. This disease has been reported in dogs and horses, but not in non‐human primates.


This paper reports on initial work in the examination of acceleration behaviour of drivers under in-service conditions. Vehicles were monitored over a 200 M section of rural road on departure from an intersection, and over 1000 individual speed profiles were produced using data logging equipment developed by the Australian Road Research Board. Considered in terms of their exit speed from the test section, maximum accelerations generated by drivers ranged from 4 km/h/s for those exiting at between 40 and 50 km/h, to 14 km/h/s for those exiting at more than 80 km/h. Mean acceleration rates for these exit speed groups ranged from 2.7 to 4.3 km/h/s. Vehicle types were divided into various performance groups on the basis of wheelbase and analysis of these groups suggested that drivers with greater performance at their disposal did utilise that additional performance to some degree. A comparison was made between in-service performance and full acceleration data available from an earlier study. This indicated that, for a medium- performing car, faster drivers wishing to leave the test section at 80 km/h were utilising 60 per cent of their likely available maximum performance (a). The paper was presented as Paper 21-Session 6-Driving Patterns (SAE 82151). The number of the covering abstract of the conference is TRIS no. 367871.


We present the gravitational wave signatures for a suite of axisymmetric core collapse supernova models with progenitor masses between 12 and 25 M⊙. These models are distinguished by the fact that they explode and contain essential physics (in particular, multi-frequency neutrino transport and general relativity) needed for a more realistic description. Thus, we are able to compute complete waveforms (i.e. through explosion) based on non-parameterized, first-principles models. This is essential if the waveform amplitudes and time scales are to be computed more precisely. Fourier decomposition shows that the gravitational wave signals we predict should be observable by AdvLIGO across the range of progenitors considered here. The fundamental limitation of these models is in their imposition of axisymmetry. Further progress will require counterpart three-dimensional models.


Research and development teams for leading suppliers of freightcar vibration control and cushioning devices often work in tandem with truck manufacturers, car builders and suppliers, and railroads to come up with products that meet marketplace demands. This article reviews the work some manufacturers are producing while seeking new ways to heed customers' call for better car cushioning, vibration control.


Abstract The rules of evidence in common law courts rely on the weight of evidence that is deduced by the court based on its admissibility and credibility. This is subject to the evidence that has been disclosed by the client to their lawyer either before or after the litigation is commenced in court. The availability of legal professional privilege is a substantive legal right (not a procedural rule) and it enables a person to refuse to disclose certain documents in a wide range of situations. There can be no adverse inference that can be drawn from a valid assertion of legal professional privilege on evidential grounds by the court. Under English law, privilege applies to the advice given by external lawyers and in-house lawyers (acting in their capacity as lawyers) in the case or in contemplation of litigation. Privilege in the US is broader than in the UK and may vary over time and according to locations/context but a privileged communication under UK law may not be privileged in the US. The Attorney-client confidentiality and work-product doctrine are the most common US types of privilege and this will protect investigation material if its primary purpose is to provide information to obtain a legal advice (i. e. if it is not for a business purpose). The research question in this paper is to what extent internal investigations need to be disclosed where the client confidentiality is not applicable and the court orders disclosure. It compares the framework under which privilege can be exercised, and how in the US a different interpretation allows greater margin for client confidentiality when investigations include another party if documents are compiled in contemplation of legal proceedings.


Commercial surf tourism is recent in origin but is now a significant component of the worldwide adventure tourism sector. There are over 10 million surfers worldwide and a third of these are cash-rich, time-poor and hence potential tour clients. Most travelling surfers visit mainland destinations and are not distinguished from other tourists. Specialist surfing boat charters and lodges are most prevalent in Indo-Pacific islands. In the smaller reef islands, growth in tourism carries risks to drinking water and subsistence fisheries. There risks are easily overcome, but only if appropriate waste and sewage management technologies are installed. In the larger rock islands, nature and adventure tourism may provide an economic alternative to logging and plantation agriculture. Cultural impacts can occur in either type of island. As with most types of adventure tourism, the commercial surf tourism industry in the Indo-Pacific is strongly linked to the clothing, fashion and entertainment industries, and marketed through specialist surfing magazines and surfing media. From a tourism development perspective, the trend is towards integrated ocean sports destinations which attract entire families as well as individual surfers. Currently, however, marketing crossovers with other specialist ocean sports such as diving are far smaller than with other boardsports such as snowboarding.


A multimedia blog creation system is described that uses Japanese dialogue with an intelligent robot. Although multimedia blogs are increasing in popularity, creating blogs is not easy for users who lack high-level information literacy skills. Even skilled users have to waste time creating and assigning text descriptions to their blogs and searching related multimedia such as images, music, and illustrations. To enable effortless and enjoyable creation of multimedia blogs, we developed the system on a prototype robot called PaPeRo. Video messages are recorded and converted into text descriptions by PaPeRo using continuous speech recognition. PaPeRo then searches for suitable multimedia contents on the internet and databases, and then, based on the search results, chooses appropriate sympathetic comments by using natural language text retrieval. The retrieved contents, PaPeRo's comments, and the video recording on the user's blog is automatically uploaded and edited. The system was evaluated by 10 users for creating travel blogs and proved to be helpful for both inexperienced and experienced users. The system enabled easy multimedia-rich blog creation and even provided users the pleasure of chatting with PaPeRo.


Faceted Search Systems (FSS) have gained prominence in research as one of the exploratory search approaches that support complex search tasks. They provide facets to educate users about the information space and allow them to refine their search query and navigate back and forth between resources on a single results page. When the information available in the collection being searched across increases, so does the number of associated facets. This can make it impractical to display all of the facets at once. To tackle this problem, FSS employ methods for facet ranking. Ranking methods can be based on the information structure, the textual queries issued by the user, or the usage logs. Such methods reflect neither the importance of the facets nor the user interests. I focus on the problem of ranking facets from knowledge bases (KB) and Linked Open Data (LOD). KB have the advantage of containing high quality structured data. With the increasing size and complexity of LOD datasets, the task of deciding which facets should be manifest to the user, and in which order, becomes more difficult. Moreover, the idea of personalizing exploratory search can be challenging and tricky, since personalization in IR (specifically precision-oriented search engines) implicitly implies narrowing and focusing the information space to retrieve the most relevant results according to the users' interests and desires. On the contrary, exploratory search systems are typically recall-oriented and they favor covering as much from the information space as possible. They also encourage diversifying the user knowledge to help them learn and discover the unknown. The generation of a ranked list of facets should be a dynamic process for a number of reasons. First of all, manually setting up facets is a time consuming task which relies upon domain experts. Second, it is not practical on large, multi-domain datasets. Even one-off automatic facet generation and ranking might not be suitable for data that changes and grows over time. Lastly, the relevance of facets can be user, query and context dependant. I am proposing a personalized approach to the dynamic ranking of facets. The approach combines different sources of information to recommend the most relevant facets. The first source is the knowledge-base from which the facets are originally generated. The second is facets generated from the top-ranked documents in a search system. The user search query is submitted to a general search engine and the top ranked documents are used to add context to the ranking process. Finally, the third source uses a user interests profile, which is collected from social media and the user's behavior in the system. These sources contribute to the final ranking score to reflect the importance of facets without ignoring user interests. My proposed research aims to answer the following research questions: RQ1: To what extent does the addition of features from retrieved search results from a general web search improve the computation of facet relevance? RQ2: What is the most effective method to incorporate personal interests and user usage data into the ranking process? RQ3: Does personalising facet ranking have a measurable impact upon the user search experience.


Objective: Vernonia amygdalina (V. amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malaria infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of V. amygdalina leaf. Materials and Methods: The active principles of the dried leaf were extracted with ethanol. For quality validation, chemical finger-print of the extract was performed through high performance thin layer chromatography (HPTLC). The extract was assessed for antiplasmodial activity by the standard four-day suppressive test on Plasmodium berghei (ANKA) infected male Swiss mice (six weeks old) placed into five groups of six animals each. Result: The absorption spectra from the HPTLC revealed several peaks suggesting presence of some bioactive compounds. Results from the in vivo study showed that the ethanol extract of the plant leaf was significantly active against P. berghei in a dose-dependent manner with the minimum and maximum activity observed in the mice treated orally with 100mg/kg (% inhibition of 23.7%) and 1000 mg/kg (% inhibition of 82.3 %) of the extract, respectively, on day four of the study. There was also a dose-dependent decrease (p<0.05) in some oxidative stress indices including nitric oxide and lipid peroxidation levels in the extract treated groups as against the non-treated infected group which had high levels of these parameters. The pro-inflammatory cytokines (TNF-α and IFN-ɣ) levels were also considerably low in the extract treated groups relative to the non-treated infected group. Conclusion: The results suggest that ethanol extract of V. amygdalina leaf was active, with some immunomodulatory effect, against P. berghei infection.


Introduction Even when sharing etiologic factors, the incidence of DM-1 is low in patients with schizophrenia. Both diseases can lead to cognitive impairment, but its difficult to define its origin. 33 years old male, with DM-1 and schizophrenia referred to Therapeutic Community for psychotic symptomatology control, cannabis consumption withdrawal, improvement of self-care and hipoglycemia control reach Objectives Nowadays toxic abstinent and adequate consciousness of disorder. Remarkable persistence of hallucinations both auditive and visual, mostly shown as delirium, pharmacologic treatment-refractary. During last months, he shows excessive absent-mindedness, recent memory failure and verbal declarative memory and psychomotor slowdown Analysis: unbalance glycosylated hemoglobin. MR: cortical-subcortical atrophy, very shocking his age. Endocrinology follow up it was decided to stablish an insulin pump, so metrics were regulated. Methods Neurological profile of the patient (deficit and slowdown attention capability) aggravation of symptoms according to glycaemia and disturbances in image test could lead to vascular origin. Attention deficit and excessive focus are symptoms of schizophrenia, but they are shown in the beginning, they tend to stabilize during years. Verbal declarative memory disruptions can be produced in both disorders Results Better glycemic control and changed to Lurasidone 37mg and Cariprazine 3mg objecting higher reactivity and less absent-mindednes Conclusions Cognitive impairment in DM is frequent in adults with severe and long evolving hypoglycemic episodes Regardless of its origin, the cognitive impairment in schizophrenia leads to serious impact in functional and pragmatic areas Further investigation will allow us to quantify the magnitude of cognitive effect in metabolic control so according strategies could be developed


To enhance teaching and management in the process of preparing for the national teaching assessment,Henan University of Science and Technology mobilized all the leaders,teachers and students to make their initiative efforts in making self-evaluation,assessment rehearsal,adjustment and improvement;as a result,there is an obvious upgrading in teaching and management,for which an A grade is given by the inspectors from the State Education Commission.


Background: Pseudomonas aeruginosa is one of the most prevalent nosocomial pathogens that cause a life-threatening infection. One of the important characteristics of P. aeruginosa is biofilm formation which leads to antibiotic resistance.
Aims and Objectives: The aim of the study was to study the antibiotic resistance pattern of P. aeruginosa isolates and correlation with their biofilm-production.
Materials and Methods: A total of 87 P. aeruginosa isolates from different clinical specimens were processed and confirmed by conventional microbiological methods as per standard methodology. Antibiotic sensitivity testing was done for all isolates. Biofilm producing isolates were identified by the microtiter plate method (MTPM).
Results: Of 87 P. aeruginosa isolates, majority were from pus 33 (38%), followed by urine 26 (30%), sputum 19 (22%), body fluids 7 (8%), and blood 2 (2%). Biofilm producing isolates showed more resistance in comparison to non-biofilm producers. The observed difference between biofilm formation for multidrug resistant and susceptible isolates was found to be statistically significant.
Conclusion: MTPM method was an effective test for detection of biofilm formation and was also able to verify biofilm production by P. aeruginosa. This indicated a higher propensity among the clinical isolates of P. aeruginosa to form biofilm and revealed a positive correlation between biofilm formation and antibiotic resistance. This indicates the need for testing of even susceptible isolates for virulence factors such as biofilm production.


2,4,6-Trinitrophenylhydrazine was synthesized by picryl chloride and hydrazine hydrate.Properties of product is similar with literature.The present paper provided a simple and convenient method.The process was optimized by orthogonal experiment and a better synthetic condition was obtained.The results showed that mole ratio of picryl chloride to hydrazine hydrate was 0.8,adding velocity was 0.02 mL /min,temperature was 8~10℃,the yield of product was 84.1%.


Inversion transformation,which was also called inversive radius vector transformation was an effective mathematical method.It has extensive application not only in many branches of mathmetics but also in solving potential distribution of electrostatic field.In this paper,the definition of inversion transformation is given firstly.Then inversion transformation and Kelvin transformation are used to center on the discussion about some properties and propositions of harmonic function,meanwhile,eight propositions of harmonic function are put forward and prove them.


Results from Brownian dynamics simulations of hard sphere diffusion in polymer networks of wormlike chains are presented. The influence of the size of the diffusing particles, the polymer concentration, the polymer radius, and the persistence length of the chains were investigated. The diffusion coefficients obtained in systems of stiff chains were compared to a theory [Macromolecules 24, 6024 (1991)]. The agreement between the simulation data and the theory was satisfactory, except for dense systems where the theory predicted somewhat too high diffusion coefficients. To account for the diffusion in systems of more flexible polymers, we derived a semiphenomenological theory based on ideas from the concept of fractals. By this approach we could show how the available volume fraction for particles in polymer networks scales with the particle radii. The scaling is not a power law, but instead is a stretched exponential, and is related to the local structure of the polymer chains. Finally, the inherent assumptions in the theoretical descriptions, e.g., the negligence of the hydrodynamic interactions, and the applicability of the theory to real polymer systems, are thoroughly discussed.Results from Brownian dynamics simulations of hard sphere diffusion in polymer networks of wormlike chains are presented. The influence of the size of the diffusing particles, the polymer concentration, the polymer radius, and the persistence length of the chains were investigated. The diffusion coefficients obtained in systems of stiff chains were compared to a theory [Macromolecules 24, 6024 (1991)]. The agreement between the simulation data and the theory was satisfactory, except for dense systems where the theory predicted somewhat too high diffusion coefficients. To account for the diffusion in systems of more flexible polymers, we derived a semiphenomenological theory based on ideas from the concept of fractals. By this approach we could show how the available volume fraction for particles in polymer networks scales with the particle radii. The scaling is not a power law, but instead is a stretched exponential, and is related to the local structure of the polymer chains. Finally, the inherent assump...


OBJECTIVE
The aim of this study was to investigate the effect of mammalian-enabled (Mena) on tongue squamous cell carcinoma (TSCC) metastasis and its mechanism.

MATERIALS AND METHODS
Immunochemistry was performed to investigate the Mena and tumor-related markers expression, and its clinicopathological characteristics in 46 TSCC specimens. TSCC cell SCC9 and Cal27 untransfected or stable transfected with Mena overexpression and small interfering RNA were used to determine the role of Mena in cell proliferation, cell migration, invasion and metastasis, and EMT-related markers in vitro, and the effect of Mena on TSCC growth and metastasis through tumor-bearing and tumor metastasis immunodeficient mice models in vivo.

RESULTS
Immunochemistry showed that the expression of Mena was significantly correlated with lymphatic metastasis and TNM stage, E-cadherin, Vimentin, and MMP2. Mena did not affect cell proliferation and colony formation in vitro, and tumor growth in vivo. However, it promoted cell migration and invasion in vitro, and TSCC metastasis in vivo.

CONCLUSIONS
Mena expression is associated with lymphatic metastasis and tumor stage and promotes TSCC invasion and metastasis by inducing the EMT process. Thus, Mena may be a biomarker for prognosis and targeted therapy in TSCC patients.


The aim of this study was to show the importance of team diagnostic in determining the appropriate treatment for the patients of the Special hospital for children with neurodevelopmental and motor disorders in order to emphasize neuropsychological perspective as well. Psychologist was the member of the team and examined various functional deficits of a child. The total sample is consisted of 200 children who had various developmental disorders and were included in occupational therapy (OT) in outpatient department during last year. In order to create a psychological profile of a child, developmental, cognitive and behavioral measures were used. The most common psychodiagnostic criteria for including a child in OT were deficits in fine motor control, visual perception and in control of behavior. In later children's age specific cognitive deficits occurred as more important. We compared recommended treatments on the first to those on the control psychological examination and they were obviously different. Interpretation of a data was made by using developmental neuropsychological approach.


Foreign and domestic experience in development of dry processing technologies are considered. The results of the introduction of dry processing technologies (cutting, boring, milling, drilling) on the industrial companies in Germany are given. The negative impact on the environment and human health is shown. The possible ways of leakage of lubricoolant components in the atmosphere and soil are considered. Lubricoolants are considered as a required permanent component. Three main tasks for lubricoolant: cooling, lubricating and chip disposal are discribed.


Energy potential of a receiver for receiving a signal from a navigation satellite is calculated according to an algorithm which is a function of the estimated value and the variance of the estimate of the mean of the correlation signal. Improving the accuracy of measuring the energy potential is achieved by improving the variance estimate. Variance estimation value is determined from the measurement of the correlation signal over a long time interval in the receiver behavior. Variance estimate is also determined by during the calibration procedure or mathematical modeling of the receiver.


This research analyses the necessity of studying the flexibility problem in the enviroment of green supply chain,and give the research framework of the flexibility problem in the enviroment of green supply chain based on SCOR.


The three-dimensional structures of four catalytic antibodies, three of which were complexed with transition-state analogs, have been determined by X-ray crystallographic methods. An additional catalytic antibody structure has been deduced using homology modeling methods, and the information derived from the resulting model has been the basis for site-directed mutagenesis experiments. Analysis of these crystal structures suggests that the primary source of catalytic activity in three of the antibodies is primarily shape and charge complementarity between the combining sites and the transition-state-analog haptens. The fourth structure may contain a modified "catalytic triad," with histidine, serine, and tyrosine side chains positioned so that they could participate in the chemical transformation. Otherwise, the abzyme structures are representative of antibody structures in general, and do not possess any particularly unusual features that would suggest a classification outside the normal range of variation expected within the immunoglobulin family. Rather, the catalytic activity of these antibodies can be explained entirely on the basis of the local arrangement of residues that line the binding sites for their haptenic antigens. In addition, the structures provide strong evidence that the conserved immunoglobulin framework can provide a highly suitable context to serve as the basis for a generalized, programmable catalyst.


Abstract After blood is removed from an animal, the biochemical parameters begin to change immediately. To ensure that results of laboratory tests accurately reflect the true physiologic or pathologic state of an individual, care must be taken to minimize such artifactual changes. It is commonly thought that delayed centrifugation of avian blood may affect analyte values; however, there have been few studies documenting changes. Likewise, the occurrence of changes in blood analyte values during preparation of a standard serum sample has not been investigated formally. This study was conducted to document the differences between analyte values in plasma and serum processed using common standardized protocols. Paired plasma and serum samples were collected from chickens. Plasma samples were kept on ice and centrifuged immediately, and serum samples were allowed to clot at room temperature for 90 minutes and then were centrifuged. The paired plasma and serum samples were simultaneously analyzed for standard biochemical analytes. Significant differences between plasma and serum values were noted for 10 out of the 17 analytes determined. Briefly, serum values for albumin, albumin-globulin ratio, and potassium were much lower than corresponding values for plasma, and the serum chloride concentration was slightly lower than the plasma chloride value. The serum globulin mean concentration was almost 3 times the value for plasma, and serum values for creatine phosphokinase, calcium, magnesium, and phosphorus were higher than their plasma counterparts.


Redacting multimedia courseware with VB to solving some problems of display and play and control on animated drawing and audio and picture and text,here we introduce some programming technique and key technology.


Abstract. Evaluation of climate model simulations is a crucial task in climate research. Here, a new
statistical framework is proposed for evaluation of simulated temperature responses
to climate forcings against temperature reconstructions derived from climate proxy data for
the last millennium. The framework includes two types of statistical models, each of which is
based on the concept of latent (unobservable)
variables: confirmatory factor analysis (CFA) models and structural equation modelling
(SEM) models. Each statistical model presented is developed for use with data from a single region,
which can be of any size. The ideas behind the framework arose partly from a statistical model
used in many detection and attribution (D&A) studies.
Focusing on climatological characteristics of
five specific forcings of natural and anthropogenic origin, the present work theoretically
motivates an extension of the statistical model used in D&A studies to CFA and SEM models,
which allow, for example, for non-climatic noise in observational data without assuming
the additivity of the forcing effects.
The application of the ideas of CFA is exemplified in a small numerical study, whose aim was
to check the assumptions typically placed on ensembles
of climate model simulations when constructing mean sequences. The result of this study indicated
that some ensembles for some regions may not satisfy the assumptions in question.


ARTICLE INFO In today's age, a damper is an integral part of design of the operating mechanism for absorbing impact force to control override and bounce during opening operation in a circuit breaker. We present, in this paper, design of two passive damper systems, rubber damper and hydraulic damper, for a circuit breaker during opening operation. The challenges in building the dampers due to the kinematics and dynamics of the complex transmission linkages and the calculation of impact force on the damper are discussed. An evaluation of the dampers based on analytical calculations for finding the maximum amplitude of vibration and simulation of static structural and explicit dynamics modules using ANSYS Workbench has been provided. The maximum equivalent stress and maximum deformation due to impact force and velocity are computed for the two dampers in each of the simulation cases. KeywordsCircuit breaker, rubber damper, hydraulic damper, shock absorption, impact, vibration. Article History Received :18 th November 2015 Received in revised form :


A photovoltaic devices inspection apparatus and a method of determining defects in photovoltaic devices using electroluminescence of the photovoltaic devices. The apparatus and method can not only determine whether the photovoltaic devices are defective or non-defective at the moment, but also whether the devices have a possibility to become defective in the future. A constant electric current is applied to the photovoltaic cells to cause electroluminescence (S7), the light emitted from each cell is photographed cell by cell (S10), and the photographed cell image is enhanced and a shape of a dark region is analyzed (S50) to determine whether the cell is defective or non-defective. The defective region that is determined to be defective is enhanced and displayed visually (S16).


The study describes the technology of fabrication of composite layers in cast steel reinforced with titanium carbides. In the process under discussion, the reinforcing TiC phase is formed in situ from the substrates deposited on mould cavity, where the said substrates under the effect of heat supplied by molten metal poured into mould (1823K) undergo a synthesis in the SHS reaction. An outcome of this process is the formation, within the casting surface, of a layer from 550 to 1200µm thick. Carbides produced in this synthesis have the size from 0,5 to 20µm and a non-typical spheroidal shape. The hardness of the produced layer examined in function of the distance from the casting surface is from 700 to 1134 HV, and is determined by volume fraction of the reinforcing TiC phase. To better document the type of microstructure obtained in the produced material, metallographic and structural examinations were carried out using the method of scanning electron microscopy (SEM), X-ray microanalysis (EDS/EDX), and phase analysis (XRD). To check the mechanical properties of the examined material, hardness was measured by the Vickers test.


GENERALIZED BHASKAR RAO DESIGNS WITH TWO ASSOCIATION CLASSES William D. PALMER Department of Pure Mathematics The University of Sydney and Department of Mathematics Sydney Institute of Education In previous work generalized Bhaskar Rao designs whose underlying design is a b~lanced incomplete block design have been considered. In the first section of this paper generalized Bhaskar Rao designs (with 2 association classes) whose underlying design is a group divisible design are defin~d. Some methods for the construction of these designs are developed in the second section. It is shown that the necessary conditions: A 0 (mod g) v 0 (mod 2 ) v ~ 6 Av(v-2) 0 (mod 3 ) are sufficient for the exi~tence of a GBRD(v,3,A,2:EA(g}) where EA(g) is an elementary abelian group of order g. Finally. the design GBRD(v,b,r,3,Al = O,A2 = A.2;EA(g) is used to construct a group divisible design with v/2 groups each of siz~ 2g and with the-parameters v ... = v g, b ... = b g, r ... = r,k'" = 3, AlII' = 0, A 2 * A/g. °


In this paper an improved method of speech enhancement using Power Spectral Density (PSD) codebooks of clean speech and several types of noise, is proposed. The proposed algorithm estimates the PSDs of speech and noise of unknown nature and evaluates the input Signal-to-Noise Ratio (SNR) by solving an over-determined set of equations as in the previous version. However, the search method used for the estimation of speech and noise PSDs is improved to assure the best match. In the former algorithm every branch in speech and noise codebooks was tracked until the lowest node (centroid) was reached. It was then used in the construction of the Wiener filter. In this improved proposed algorithm the centroids, from speech and noise codebooks, whose combination results in the best match of the noisy speech frame PSD, are selected no matter their locations in the corresponding code-book trees. Experiments show that better results are always obtained in comparison to the previous algorithm. However, other methods are tried to smooth further the PSD of speech and noise prior to their use in the Wiener filter for speech enhancement to confirm that best results are obtained by using the best match with no smoothing.


ABSTRACT Manifest in research, national policy, and instructional standards, the United States has a long-documented interest in teachers as 'content experts.' Yet, research offers limited empirical examinations of teachers' discipline-specific critical content knowledges—their curricular agility in noticing and disrupting power and oppression, and working to promote empowerment, joy, and liberation. Accordingly, this study asks: what critical content knowledges are most prominent among social justice-oriented secondary English language arts (ELA) teachers, and how do teachers understand and describe these knowledges? Using collective case study methodologies, this study investigates interview data from five ELA teachers to understand participants' critical content knowledges and their descriptions of these knowledges. Data were interpreted through deductive and inductive coding and analysis. Findings reveal that teachers' most prominent critical content knowledges include a) knowledge of disciplinary critique; b) knowledge of marginalized identities; and c) knowledge of supplementary content. Limitations to teachers' critical content knowledges include a narrow race and gender foci, and discursive avoidance of explicitly naming marginalized identities. Implications for future research aimed at better understanding, supporting, and expanding teachers' critical content knowledges are discussed.


Triterpenes, α-amyrin, oleanolic acid and ursolic acid were previ ously described as the active components present in Ficus pseudopalma . It was also reported to have a strong scavenging activity against various free rad icals, owing to aforementioned phytochemicals. In the present study, comparison of the antioxidant capacity of the standard triterpenes was performed using microtiter plate method. General antioxidant tests such as DPPH and FRAP assays and specific tests for the scavenging activity towards nitric oxide (NO•), superoxide (•O 2 - ) and lipid peroxides (LOO•) were done. Thin layer chromatography of the crude ethanolic le af extract of F. pseudopalama together with α-amyrin (0.831), oleanolic acid (0.769) and ursolic acid (0.769) revealed that two spots from the extract correspond to that of the standard compounds. Results showed that α-amyrin, oleanolic acid and ursolic acid are proton donors, all having an IC 50 value of >333.33µM and possess a reducing power (RC 50 >909.09µM).


Minimax problem is a kind of important optimization problems.Aggregate function method is a kind of new effective method for it.Aggregate homotopy method has avoided some disadvantages that caused by ill condition of original aggregate function method,and weakened condition for convergence in the large field.In this paper,we present a modified aggregate homotopy method.The homotopy is piecewise-defined.Because it keeps the monotonicity of the aggregate function,the convergence can be proven easily under weaker conditions and the algorithm will be more effective.


The paper reviews the development and use of the Primary Quantum Voltage Standard at NIM, including the international comparison with BIPM


One important application in Vehicular ad hoc networks, VANET, is applied for the cooperative collision avoidance (CCA) in the intelligent transportation system, ITS. In CCA, a driver could broadcast emergency messages to advice the vehicle behind accident through VANET. Thus how to design an efficient broadcasting method for forwarding the emergency messages is important in ITS. However, most of researches focused on avoiding broadcast storm by selecting only one forwarder for broadcasting. In this way, it caused that emergency messages could not be spread in other direction roads. Thus the cars in these directions of the crossroad cannot receive the emergency messages to prevent the traffic accident. To address this issue, we proposed an emergency messages broadcasting by multi-forwarder (EMBM) to select the appropriate forwarders for each brand at the intersection. Thus the emergency message could be forwarded through each brand when the messages were broadcasted across the intersection. The simulation results showed that the reachability in EMBM was 44.9 % and higher than that in binary partition assisted broadcast (BPAB), and 46.6 % higher than that in cell broadcast for streets, CBS. The average delay time of EMDM was 32.3 % lower than that in BPAB, and 69.1 % lower than that in CBS.


The LIght Detective Raging (or LIght Detection and Ranging/LIDAR) is a technology based upon remote sensing. The main advantage of applying LIDAR to crime scene documentation is that we can obtain the true-to-scale and non-contact measurement of scenes. However, there are some properties and limitations of LIDAR we should notice when we use it. In this paper, we demonstrate how to apply LIDAR to 3D crime scene data acquisition and point out some particular surfaces that should be considered and prevented. The acquisition and electronic storage of the true-to-scale color digital data can be seen as a virtual conservation of evidence and crime scenes. Finally, three real crime scene cases are proposed to show the performance of applying LIDAR at crime scenes.


The invention relates to a process for the preparation of Refinerholzstoffen, wherein the wood chips were irradiated after a slight impregnation with bisulfite and high-energy radiation and subsequently fiberized with refiners. The method HSB-TMP (TMP wood chips with radiation) is characterized in that 30-50% of the specific energy consumption can be saved in the defibration. The papers made from recycled multistage HSB Refinerholzstoffen possess upon receipt of the strengths improved optical and surface properties.


Electrical module is the control unit of oil and gas processing, so it must have the ability to withstand the impact of the explosion. By transient dynamic module of ANSYS, dynamic response of electrical module under explosion load is analyzed. The results show that the maximum stress and displacement of electrical module are larger. Through ANSYS structural optimization, the maximum stress of electrical module decreases from 336 MPa to 269 MPa, the maximum displacement reduces to 16.9 mm from 22.7 mm.


Understanding the delicate balance of forces governing helix or β‐hairpin interactions in transmembrane (TM) proteins is central to understanding membrane structure and function. These membrane constituent interactions play an essential role in determining the structure and function of membrane proteins, and protein interactions in membranes, and thus form the basis for many vital processes, including TM signaling, transport of ions and small molecules, energy transduction, and cell–cell recognition. "Why does a single‐pass TM helix or β‐hairpin have specific orientations in membranes?" "What are the roles of hydrogen bonds, close packing, and helix‐lipid or β‐hairpin‐lipid interactions in helix or β‐hairpin associations in membranes?" "How do these interactions change the membrane structures?" "How do TM domains transmit signals across membranes?" These are important membrane biophysical questions that can be addressed by understanding the delicate balance of forces governing helix or β‐hairpin interactions with/in membranes. In this work, we summarize a series of helix/β‐hairpin restraint potentials that we have developed, and illustrate their applications that begin to address the complicated energetics and molecular mechanisms of these interactions at the atomic level by calculating the potentials of mean force (PMFs) along reaction coordinates relevant to helix/β‐hairpin motions in membranes and dissecting the total PMF into the contributions arising from physically important microscopic forces. © 2009 Wiley Periodicals, Inc. J Comput Chem 2009


Champlin and Wright {''Manipulations of the duration and relative onsets of two‐tone forward maskers'' [J. Acoust. Soc. Am. 94, 1269–1274 (1993)]} examined the effects of masker duration in forward masking with one‐ and two‐tone maskers. They found, among other things, that the amount of psychophysical suppression increases as the temporal overlap between the two masker components increases. They proposed a two‐stage neural model to account for this finding. The purpose of this Letter is to show, experimentally, that their results are consistent with an explanation based on mechanical suppression.


Aim To explore the effect of chemical hypoxia-mimetic agent,cobalt chloride(CoCl2)on inflammatory reaction in human keratinocytes(HaCat cells).Methods After HaCat cells were treated with CoCl2 at different concentrations to set up a chemical hypoxia-induced cell model of skin injury,cell viability,intracellular reactive oxygen species(ROS),mitochondrial membrane potential(MMP),the levels of both interleukin 6(IL-6)and interleukin 8(IL-8)as well as the expression of heme oxygenase-1(HO-1)were detected.Results The viability of HaCat cells was reduced by CoCl2 at the concentrations from 500 to 3 000 μmol·L-1,and the higher CoCl2 doses,the lower cell viability was.CoCl2 induced oxidative stress reaction(increasing ROS production and decreasing MMP).CoCl2 induced inflammatory reaction,enhancing the release of IL-6 and IL-8.CoCl2 at concentrations from 1 000 to 3 000 μmol·L-1 upregulated HO-1 expression in HaCat cells.Conclusion CoCl2 induces not only oxidative stress,but also inflammatory reaction,increasing the release of both IL-6 and IL-8,as well as HO-1 expression.


Abstract Starch and fibre contribute to the energy components and add functionality to the end-product feed ingredients. An understanding of the impact of processing on carbohydrate content will support accurate formulation of feed. Six ingredients, grown or sourced in Canada, were used in this study. They included five pulses, Amarillo peas, Dun peas, chickpeas, lentils, and faba beans, and soybean meal (SBM) as a comparison. All ingredients were ground into fine or coarse products and then pelleted at one of three different temperatures. Grinding reduced the total starch (TS) content of Amarillo peas and chickpeas (P < 0.05), crude fibre (CF) in Dun peas (P < 0.05), and total dietary fibre (TDF) and insoluble fibre (IDF) in lentils (P < 0.05). Grinding only affected soluble fibre (SDF) in chickpeas. The effect of pelleting was variable for TDF across pulses. Pelleting did not affect the SDF content of pulses (P > 0.05). Finely processed SBM had higher (P < 0.05) TS, TDF, and IDF content than coarsely processed SBM. Results indicate that grinding and pelleting could affect the starch and fibre composition of some pulses.


Brazil is the fourth largest milk producer with 15.9% increase in its production in the last five years, showing potential to become the world's largest exporter of milk.However, for it is necessary to produce milk with low cost and high quality. Minas Gerais is the largest milk producer, with 27.3% of national production.Milk production in Brazil is developed mainly in pasture systems, which gives the milk produced, low production cost. However, production of dairy cattle based only on use of tropical pasture systems does not attend the high demand for individual productions or even for medium productions. Studies demonstrate the potential of milk production from intensively managed pastures, allowing increased milk production per area and the association with the use of feed concentrates maximizing milk production per cow. The combination of these twotechniques managements enables increase in milk production significantly.


The raise of social Web brought new ways of disseminating information, news and published content over the Web. Social news aggregator Web sites such as Digg and Reddit are already known for their role in promoting user-based content by utilizing story submission and voting system. Balatarin, the first and one of the most famous news aggregator in Persian language, is a social book marking Web site, which is developed by combining the underlying idea of Reddit, Digg, News vine and Del.icio.us. Although Balata in is among popular and influential Web sites in the Middle East, there has not been any analytical research on it. Here, we studied the user activity to see whether it is dominated by few users' participation, or social incidents can motivate users and influence their contribution. For our study, we collected data representing user activity over the course of three years. We carried out some computational analysis on user participation under social circumstances, such as blockade and election in Iran. The evaluation of the results shows that such social factors can motivate users to break the tyranny of the minority submitters by contributing more.


Breast cancer is the most common cancer in women worldwide. It is also the principle cause of death from cancer among women globally. Mammogram image is considered as the most reliable, low cost, and highly sensitive technique for detecting small lesions. Computer-aided diagnosis system (CAD) can be very helpful for radiologist in detection and diagnosing abnormalities earlier and faster than traditional screening programs. In this work a CAD system to distinguish between masses and normal breast tissue was proposed. We started our system by using DDSM database for mammogram images which were first preprocessed using image enhancement algorithm, then 100 regions of interest (ROIs) containing masses and normal breast tissue are extracted. Then we extracted a group of 59 texture and statistical features from the ROIs. Then we performed feature selection using Sequential Forward Selection and Sequential Floating Forward Selection. Finally we used K-Nearest Neighbor (KNN) classifier, Linear Discriminant Analysis (LDA), Quadratic Discriminant Analysis (QDA), and Support Vector Machine (SVM) classifier for classification with leave-one-out method for testing. The obtained results show acceptable sensitivity and specificity for the system.


GaN thin films on Si(001) substrates are studied by infrared reflectance (IRR) spectroscopy at room temperature (RT). Variations in the IRR spectral line shape with the microstructure of GaN/Si(011) film are quantitatively explained in terms of a three-component effective medium model. In this model, the nominally undoped GaN film is considered to consist of three elementary components, i.e., single crystalline GaN grains, pores (voids), and inter-granulated materials (amorphous GaN clusters). Such a polycrystalline nature of the GaN/Si(001) films was confirmed by scanning electron microscopy measurements. It was demonstrated that based on the proposed three-component effective medium model, excellent overall simulation of the RT-IRR spectra can be achieved, and the fine structures of the GaN reststrahlen band in the measured RT-IRR spectra can also be interpreted very well. Furthermore, the volume fraction for each component in the GaN/Si(001) film was accurately determined by fitting the experimental RT...


Aimed at finding an engineering method to prevent or alleviate issues of degradation of ecosystem,non-point source pollution and the destruction of biodiversity and so on,an ecological landscape type irrigation and water conservancy slope based on expounding the role and hydrological effects on the mechanism of slope protection plant was designed.Then,the optimized and the controlled experiments of nonpoint source pollution elimination were carried out with a land renovation project of Shanghai city as the study case.Finally,the ecological service value model was introduced to evaluate the ecological effect.Results showed that:the optimized slope had good removal effects on COD,NH+4-N,TN and TP,and the average removal rates increased by 50.03%,29.97%,35.20%,51.58% respectively.The optimized slope could increase the area of the green by 11.48hm2.And the total value of ecosystem service increased8.9times in experiment zone after optimization.What's more,the optimized slope added new functions of farmland protection,habitat protection,isolation of pollution belt,natural landscaping and so on,which had more benefits of economy,society,ecology and landscape.


As a kind of supported bilayer lipid membranes, hybrid bilayer membrane (HBM) was applied to the interaction between Ca2+ and lipid for the first time. By using Fe(CN)(6)(3-) as a probe, we found that Ca2+ could induce the ion channel of HBM to be in open state. STM images study proved this phenomenon.


Summary
Samples of two potato cultivars (Agria and Merit), cultivated either conventionally or organically, were analysed to evaluate their suitability to transformation into powder. Agria cultivar potatoes from the conventional farming were selected as the most suitable for drying process both for their high-dry matter and good nutritional value. Blanching resulted in the most effective treatment to prevent potato browning. The potato powder was obtained by means of a drum dryer using different process parameters (temperature, time and product thickness) to minimise thermal damage on the final product. The effects of these different processes were evaluated by analysing some quality indicators, as final moisture, nutrients (carbohydrates, proteins and amino acids) and colour of the powder, and rheological properties of the rehydrated puree. The results of such analyses showed that the lower the process temperature, the better the powder quality.


Antifreeze activities of various oligo- and poly(amino acid)s, more particularly oligo(glutamic acid)s (OGAs) and poly(glutamic acid)s (PGAs), were measured by differential scanning calorimetry (DSC). The polymers composed of acidic amino acids, such as PGA, had higher antifreeze activity than the other polymers. The antifreeze activities of the OGAs and PGAs tended to decrease as their molecular weights increased. However, their activities in the molecular weight range below 20 000 were higher than the antifreeze activity of glucose, which is known as a highly antifreeze substance. The antifreeze activities were only slightly affected by the optical isomerism and the peptide linkage type and decreased in the order Na salt = K salt ≫ Ca salt ≫ acidic form. It was considered that the high antifreeze activities of OGA and PGA are mainly caused by Coulomb's force of the dissociating counterions. Keywords: Antifreeze activity; oligo(glutamic acid); poly(glutamic acid); molecular weight; counterion


Documentary films are so-called non-fiction films that have the elements of persuasion, objective content and candid cinematic techniques. It is an important propaganda tool for assisting the government in the development of the country and changing people's attitudes. The Freedom Film Fest, held annually since 2003 by the Community Communications Center, provides indie documentaries an alternative and more freedom for indie documentary filmmakers to represent social, economic and political issues. However, this genre of media has not received much attention especially from the youth or film industry as it is considered a less attractive medium. Most indie documentary filmmakers no longer produce documentaries as they are not well received. The objective of this study is to identify the problems faced by documentary filmmakers, especially those called indie filmmakers in Malaysia. Interviews with five indie documentary film makers and filmmakers were conducted in this research to examine the problems they faced in producing documentary films. The results have shown that the lack of distribution and broadcasting platforms, finance, promotions, legal restrictions, production techniques and flawed production plans are the main problems faced by indie documentary filmmakers in the Malaysian industry. Keywords: Indie documentary film, documentary filmmaker, Malaysia film industry, broadcasting and distribution, Critical thinking.


Abstract 2127 Poster Board II-102 Background: The revised model of coagulation proposes that factor XI (FXI) can be activated by thrombin, which is generated upon activation of the tissue factor (TF) pathway. This concept, however, has not been tested in vivo. A recent study questioned the existence of this feedback loop and suggested that factor XII (FXII) is the sole activator of FXI. Here, we analyze the feedback activation of FXI in plasma and in genetically altered mice. Methods and results: Fluorescence-based assays indicated that particle-bound thrombin caused thrombin generation in plasma both in the absence of TF and in the presence of active site inhibited factor VIIa. Thrombin failed to activate FXII and thrombin generation was almost completely abolished by an anti-FXIa antibody and in FXI-deficient plasma. Surface bound thrombin induced complex formation of FXI, with its major inhibitor C1 inhibitor, even in FXII-deficient plasma in a time and dose dependent manner. To determine if thrombin-driven FXI activation is important for hemostasis in vivo we used TF deficient mice (low TF), which have severely reduced thrombin formation. Low TF mice were crossed with mice deficient in one of the intrinsic pathway proteases FXII, FXI, or FIX. Double deficiency in TF and either FIX or FXI resulted in the intrauterine death of embryos due to hemorrhage. In contrast low TF/FXII-null mice were viable and the bleeding phenotype was unchanged from low TF animals. Conclusions: Surface-bound thrombin, a model for fibrin clot-protected thrombin, generates thrombin in a FXI dependent manner, independently from FXII. In addition to corroborating an amplifying role of FXI in thrombin generation, we provide the first evidence that at low TF levels FXI is essential in generating a sufficient ambient level of thrombin to permit embryonic development. Disclosures: No relevant conflicts of interest to declare.


From the fully mechanized coal mining in the medium thick seam,the thin seam mining and the shortwall mechanized mining,the paper in detail stated the development status of the fully mechanized coal mining technology and equipment in China and introduced the new breakthrough on the key technology and equipment.The paper analyzed the gap existed between the fully mechanized mining equipment made in China and the overseas products.From the improvement of the automation degree and the key parts reliability,the paper provided the development tendency of the fully mechanized coal mining technology.


A free electron laser (FEL for short) facility based on superconducting (SC for short) accelerator is under construction at Peking University (named PKU- FEL).This system is composed of a SC injector, a SC linac, undulators/wigglers and other subsystems. In January 2003, the DC-SC photoinjector test facility was constructed, and after a year of commissioning and testing, we have accomplished the first successful step. The performance of this new injector is to be further improved. The main linac comprises two TESLA-type 1.3-GHz 9-cell cavities and a Rossendorf-type cryostat. The two 9-cell cavities will be fabricated by ACCEL and low-power cold test will be carried out at DESY. The undulator is developed jointly by the Institute of High Energy Physics and Peking University. Prototype of the undulator has been completed, validating the quality of the permanent magnets and the reliability of the construction. Meanwhile, the photocathode, the driving laser, and the beam diagnostic system have been tested and developed. PKU-FEL will run in THz and IR region. High average power FEL should be feasible, as the SC accelerator can run in CW mode. R & D in the field of Radio Frequency (RF for short) superconductivity has been in progress all along at Peking University. Researches are going on to improve the performance of SC thin films prepared by sputtering technology. Design of a 2+1/2-cell Nb Cavity for injector has been accomplished; manufacturing has been carried out. Researches on SC accelerator based ERL (Energy Recovery Linac) light source are also in progress.


Human thyrocytes were found to synthesize and secrete the selenoenzyme extracellular glutathione peroxidase (E-GPX), a process which was controlled by the Ca2+/phosphoinositol second-messenger cascade. The potential involvement of thy-INTRODUCTION


Most of the readers of this journal can perceive the full range of colors in the visible spectrum and, thus, are able to discriminate among the color-coded bases of the DNA graphic on the cover and enjoy the intrinsic beauty of multicolor FISH micrographs and the brightness of dye-labeled sequencing fragments on the screen of an automatic DNA sequencer. We appreciate the palette of impressionist painters, and we deal freely with yellow submarines, green traffic lights, and red emergency buttons.


Monazite crystals from a 50 m wide quartz vein in Montgomery County, North Carolina show the alexandrite effect. The crystals are reddish-orange under incandescent light, yellow-orange in daylight, and light green under fluorescent light. The colors are due to nutro* absorption bands from Nd3+ at about 800, 745, 5E0, 525, and 515 nm, and an absorption edge beyond -480 nm. The monazite is chemically unusual in containing virtuatty no Th, U, or iron-group elements, which can cause deep colors that mask the pastel rare earth-produced colors. The alexandrite effect in this monazite differs from that in previously desiribed substances in being due to several narrow absorption bands rather than a small number of broad bands.


This experiment was conducted to evaluate the effects of different levels of Portulaca oleracea (PO), medicinal plant, on performance, egg traits, blood biochemical and immunity parameters of laying hens. One hundred eighty Hi-Line (W-36 strain) mature laying hens 65 up to 76 weeks of age were allotted in a completely randomized design consisting of 5 treatments and 3 replicates (12 birds per replicate). Treatment groups consisted of a control group (1) with no PO supplementation and experimental groups 2, 3, 4 and 5 which contained 0.5%, 1.0%, 1.5% and 2.0% of PO powder, respectively. Using different levels of PO significantly affected the performance, egg traits, blood biochemical and immunity parameters of laying hens (P<0.05). The highest values for egg weight, egg production percentage, egg mass, feed intake, feed conversion ratio, egg yolk color index, albumin percentage and blood high density lipoprotein (HDL) were obtained by feeding 2.0% of PO. The highest level of blood hemoglobin was observed by feeding 1.0% of PO. The overall results showed that feeding Portulaca oleracea powder up to 2.0% in the diet has a positive effect on mature laying hens performance and egg traits.


Objective: To analyze epidemiology of out-of-hospital cardiac arrest (OHCA) managed by emergency medical service (EMS) in the territory of Kanjiža municipality. Methodology: Information for this research was taken from the unique registry of out-of-hospital cardiac arrest, established by Resuscitation Council of Serbia through an online questionnaire. Head researcher entered the data after every OHCA managed by EMS team. SPSS program was used for statistical processing. Results: Through the observed period (October 1st, 2014 to December 31st , 2016) 22 cases of OHCA with initiated resuscitation measures were recorded. Gender distribution of OHCA shows the majority of male patients. The most common cause of OHCA was cardiovascular and the most common place of event was home of the patient. 17 patients suffered OHCA in front of a witness but only 4 times witness has started CPR before EMS arrived. Telephone assisted CPR was not used in any of the cases. Initially shockable rhythm, ventricular tachycardia without pulse or ventricular fibrillation (pulseless VT/ VF) was registered 4 times, and ROSC was achieved 2 times. None of the patients survived to be discharged from hospital. Conclusion: It is necessary to make a greater effort towards citizens' education and raising their awareness of the significance of starting the early basic life support measures, before EMS arrives. Another important task that is ahead of us is education of emergency dispatchers on providing telephone guided CPR, especially in cases of distant intervention locations, so that the EMS could literally buy time until arriving.


The introduction of European standards in the training of competent, highly qualified specialists who are able to use the theoretical knowledge acquired in the learning process in practice, has led to increased requirements for the quality of their professional development. Clinical anatomy and operative surgery is a discipline that allows students to apply clinical thinking in practice, because only on the basis of knowledge about the anatomical features of the structure of a particular part of the human body can choose successful surgical treatment tactics. The aim of the work was to highlight the peculiarities of teaching clinical anatomy and operative surgery at the Department of Operative Surgery and Clinical Anatomy of I. Horbachevsky Ternopil National Medical University and ways to improve them in modern conditions. At the Department of Operative Surgery and Clinical Anatomy of I. Horbachevsky Ternopil National Medical University pays attention not only to the theoretical but also to the practical component of student training. Students independently conduct training operations on experimental animals, thus consolidating theoretical knowledge and gaining practical skills, learn to work in a team, perform other functional duties of members of the operating team, and in the postoperative period observe the body's response to surgery. The transition of the educational process to the distance form with the introduction of the online platform Microsoft Teams made it possible to conduct classes in real time, and the use of an interactive method of business game allowed to 'virtually' conduct educational operations. The use of virtual and augmented reality technology gives students the opportunity to learn more about the subject, to gain experience to which they do not have access, especially in conditions of quarantine restrictions.


One of the benefits of smart houses is empowering the special needs in their daily life. There is clear effort in helping special needs live independently yet it's not widely implemented in the UAE. This study aimed to give insight into the efforts of supporting their daily activities regarding health, security and time-efficiency. It investigated and identified the impact of implementing smart environments to overcome disabled people's struggles and obstacles in their ADLs. This research used three data collection techniques; survey, questionnaire and interview. Using these techniques, it's clear that smart homes are useful for special needs in many aspects. The main result of the research was its time efficient; but based on the task and experience. The privacy and security level(s) depend on the family and the individual's condition, it can serve their health needs per their health condition. The effects of smart homes might permanently change the living styles of special needs people in the Emirati culture.


This paper presents a theoretical framework for linearization and stabilization of second-order nonholonomic chained systems. By giving a new criterion for the problem of nonsmooth nonregular feedback linearization, it is proved that second-order chained systems are nonregular static state feedback linearizable. A discontinuous control law is obtained based on linear system theory and the inversion technique. Simulation studies are carried out to show the effectiveness of the approach.


Ultra-stable oscillators (USO) were developed for Radio Science instrumentation on deep space missions functioning as frequency references for the one-way downlink during atmospheric occultations and other experiments. They have also proven to be very stable references for all one-way communication links. USOs have also been flown on planetary entry probes including the Galileo Jupiter probe and the Cassini-Huygens Titan probe for the purposes for Doppler Wind Experiments. These two probes utilized different oscillators, quartz US0 for Galileo and Rubidium US0 for Huygens. This paper presents the historical development and the latest technologies for ultra-stable oscillators including the latest trends in improved stability and reduction in mass, volume and consumed power. It also discusses the tradeoffs for US0 type selection, including factors such as duration of the experiment, the available warm-up time and the Allan deviation and phase noise requirements.


The purpose of the designed device is to simulate transfer of low-potential heat from rocks by means of a collector with cooling fluid and heat pipes in laboratory conditions. It is also possible to perform measurements of heat flows at identical input temperature conditions and at different heat pipes filling (CO2, NH3) at various pressures during filling the pipes. The device (simulator Fig. 1) for the transport of low-potential heat through stage conversions in the evaporation and condensation sections of the pipes at temperatures below 0 °C enables the development of research activities for the verification of manufacturing technology of heat pipes suitable for the use of low-potential geo heat in laboratory conditions. Individual components of the device allow the investigation on thermo kinetic parameters of heat transport from rocks to the heat carrier on the model. The ANALYSIS OF TRANSMISSION PHENOMENA IN LOW-POTENTIAL HEAT TRANSPORT BY HEAT PIPES IN THE DEEPBOREHOLE SIMULATOR Richard Lenhard – Michal Jakubsky – Milan Malcho – Jozef Jandacka *


A system for detecting an internal network host causing a spoofed DDoS(Distributed Denial of Service) packet in real time and a method therefor are provided to find out a port on a switch which transmits the spoofed DDoS packet, thereby detecting a host computer that generates the spoofed DDoS packet by being connected to the corresponding port. A sensor(300) comprises as follows. A monitoring unit(310) monitors traffic through a switch. A traffic amount comparator(321) compares/analyzes whether an amount of the monitored traffic exceeds a reference amount of traffic. If so, a packet information collector(322) demands/receives packet information for each port to/from the switch. A port selector(323) compares header information with MAC(Medium Access Control)/IP(Internet Protocol) information of host computers of each port to select a port that sends a spoofed DDoS packet. A storage unit(324) stores the MAC/IP informatino of each port.


The importance of the Pacific Rim nations to the United States has become increasingly well recognized by many, as well as the need to consider possible implications for our educational system. As a result, in 1986 a Commission was appointed by California State University to investigate ways to develop closer relations between the university and its Pacific Rim neighbors. The report (Pacific Rim commission of the CSU, 1987) issued by the Commission recommended three changes to better educate students from an international perspective, i.e., the establishment of intemational business internship programs, requiring a foreign language requirement of international business majors, and great internationalization of the curriculum. The objectives of this study were to examine (1) the extent of the support for these recommendations among recruiters of accounting graduates (i.e., accounting firms, business organizations and governmental entities), (2) the relative importance of specific topics which might be incl...


Absiracr The photoluminescence (PL) peak of were excited by the 457.9 nm line of an Ar+ laser, and porous Si (PS) will shift towards blue after it is oxidized in measured at room temperature by a Spex-1702 an ozone atmosphere and then deoxidized in m. This monoc~omator~ the p~ spectra have been corrected proves that the origin of the PL is due to the quantum Confinement (QC) effect. By using two-step anodization to for the response ofspectrometer.


Self-hardening aluminium alloy AlZn10Si8Mg represents an innovative class of light aluminium alloys and they present high mechanical properties, which make them suitable for many applications in different industrial fields, especially in transport industry. The most important and relevant feature of the self-hardening alloys is related to their good performance, without the need of any heat treatment: they are subjected to a natural ageing phenomenon at room temperature after a storage period of about 7-10 days. The possibility to avoid the heat treatment represents an important benefit, contributing to considerably reduce both the production cost of some components and the amount of energy. Furthermore, without heat treatment the risk of component's deformation during the production is eliminated.The Charpy impact energy of experimental cast alloy was measured at -196°C, -20°C, 20°C, 50°C, 100°C, 150°C, 200°C, 250°C, 300°C, 350°C and 400°C in terms of the total absorbed energy. Effect of temperature to microstructural changes and fracture surface on the impact toughness was investigated. A combination different analytical techniques (light microscopy upon black-white etching, scanning electron microscopy (SEM) upon deep etching) were therefore been used for the identification of the various phases.


Objective:To compare the killing effects on HCC SMMC-7721 cells of immunoliposome PE38、immunotoxin PE38 and liposome PE38. Methods:Dissolute PC,CHOL and CHS in chloroform in proportion.Dry membrane was formed after chloroform was removed.Add the protein solution of PE38 to dissolute the dry membrane.Then pass the solution over a Sephadex G-50 column after ultrasoned and filtrated to detect the encapsulation efficiency of the liposome.The solution reacted in EDC,SSNHS and MES for 30 minutes.Then add Ab to the solution in 4℃ over night.MTT method was used to detect the killing effects on HCC cells of immunoliposome PE38、immunotoxin PE38 and liposome PE38 in vitro. Results:The killing effects on HCC cells of immunoliposome PE38 is the best,and that of liposome PE38 is the worst.The respective IC_(50) s are:0.59 μg/ml、6.04 μg/ml and 92.07 μg/ml. Conclusion:Immunoliposome PE38 may be a protential durg in the treatment of hepatocarinoma.


Earthworms are the important biological indicator for soil ecosystem.The acute toxicity test of two veterinary pharmaceuticals containing arsenic-roxarsone and arsanilic acid to earthworms(Eisenia Andrei) was studied using three methods.The LC_ 50 of roxarsone and arsanilic acid to earth worms using artificial soil test,arsol test,natural soil test were 3.23,2.99,3.45 g·(kg dry soil) -1 and 5.80,5.10,6.80 g·(kg dry soil) -1 respectively.The toxicity of these two veterinary pharmaceuticals to earthworms was low.


As one who tried and failed, I sincerely admire the accomplishments of the Stop Hypertension with the Acupuncture Research Program (SHARP) described in this issue of Hypertension .1 As Macklin et al1 note, this is the largest double-blind, randomized, sham-controlled clinical trial of acupuncture for treating hypertension to date. When the work involved in reaching their definitive conclusion is considered, it seems likely (and hopefully) to be the last such trial of acupuncture for hypertension. Again quoting Macklin et al, "Acupuncture has been used in traditional Chinese medicine to treat symptoms related to hypertension for over 2500 years" and "Today, acupuncture is commonly used to treat hypertension in China and the West."1

The amount of time, energy, and money expended …


This paper introduces a method on no-listed corporation valuation in detal a CAPM method based on DCF, by analyzing the case of an non-listed software corporation .Specifically, a proper (3 can be derived through the similar data of the listed corporations; CAPM formular may help to get the return of asset or discount factor; with these parameters. DCF method can be used to fulfil the valuation of listed corporations.


The Department of Immigration, Multicultural and Indigenous Affairs (DIMIA) now has the capacity to track those leaving and entering Australia across successive movements. An examination of residents leaving Australia in 1998 to 1999 who indicated that their departure was permanent shows that by 30 June 2003, 24 per cent had not left permanently.


To eliminate fault correspondence, improve matching precision and recover dense depth image with high accuracy, a stereo matching method using multiple stereo pairs with various baselines was presented to obtain precise scene distance value without suffering from ambiguity. The constraints of epipolar geometry, uniqueness, smoothness and local normalizing process were imposed on the stereo images for uniquely finding corresponding points. The result shows that the errors of depth data are, on the average, less than 2 mm at distance between 1 5 m to 3 5 m away from the cameras.


For non-Hermitian quantum models, the dynamics is apparently not reflected by the static properties, e.g., the complex energy spectrum, because of the nonorthogonality of the right eigenvectors, the nonunitarity of the time evolution, the breakdown of the adiabatic theory, etc., but in experiments the time evolution of an initial state is commonly used. Here, we pay attention to the dynamics of an initial end state in nonreciprocal Su-Schrieffer-Heeger models under open boundary conditions, and we find that it is dynamically more robust than its Hermitian counterpart, because the non-Hermitian skin effect can suppress the part leaking to the bulk sites. To observe this, we propose a classical electric circuit with only a few passive inductors and capacitors, the mapping of which to the quantum model is established. This work explains how the non-Hermitian skin effect enhances the robustness of the topological end state, and it offers an easy way, via the classical electric circuit, of studying the nonreciprocal quantum dynamics, which may stimulate more dynamical studies of non-Hermitian models in other platforms.


The presence of ovarian GnRH and/or compounds with GnRH-like activity was investigated in the goldfish ovary. Goldfish ovary was extracted using an acetone/HCl/ether mixture and was purified by Waters C-18 Sep-Pak columns (ovarian extract). The goldfish ovarian extract was found to 1) stimulate gonadotropin release and subunit messenger RNA production in the goldfish pituitary that was inhibited by a GnRH antagonist; 2) stimulate germinal vesicle breakdown in the prophase-I arrested follicle-enclosed goldfish oocytes in vitro, which was inhibited by a GnRH antagonist; 3) immunoreact with various GnRH antisera; and 4) bind to GnRH receptors in the goldfish pituitary and ovary as well as rat pituitary. Further purification with HPLC revealed the presence of two compounds with GnRH-like activity. One with identical chromatographic characteristics, amino acid composition, and primary structure to that of the salmon GnRH (sGnRH), and the other a novel compound with GnRH-like activity.


Building a prototype air contactor and absorbing carbon dioxide from ambient air for 5-6 days outdoor operation to test our packing-based contactor design in an operational environment. Our operation with pulsed liquid flow allows us to fully wet the surface of our structured packing with a brief period of full flow, then to cut flow for duration of several minutes to let the liquid slowly react away as CO2 is absorbed. The prototype contactor is manufactured from PVC or stainless steel depending on the cost per-surface-area, solvent used and pressure drop on per-surface-area basis. This prototype focuses on wet-scrubbing air contactor design that is rooted in the gas scrubbing and cooling tower industries and to regenerate our captured purified pipelinequality CO2. Extraction and usage of pure CO2 from guanidine complex or Na2CO3 by slight heating or titration can be done.


1. G. Hardy and M. V. Subbarao, On a problem of Pillai and some related questions, Leaflets in Mathematics, Proc. Number, Functions, Equations, International Conference dedicated to the 60th birthdays of Professors Zoltan Zar6czy and Imre Katai held at Noszvaz, Hungary, Zsolt P'ales, ed., May 31-June 6, 1998, pp. 142-143. 2. S. S. Pillai, Question 1490, J. Indian Math. Soc. 18 (1930) 230. 3. J. V. Uspensky and M. S. Heaslet, Problem 1 in Elementary Number Theory, McGraw Hill, New York, 1930, p. 157.


It is considered formation of a partly regular microrelief on the surface of parts. The characteristics for the evaluation of non-standard parameters of the microrelief.