L-methionine Di-Sulphoximine (MSX) a well known inhibitor of glutamine synthetase (GS) was used at 10, 50, 100 and 500 μM concentrations to heck if ammonia excretion by the cyanobacterium, Mastigocladus laminosus was concentration-dependent. It was found that MSX at concentrations beyond 50μM inhibited ammonia release by M. laminosus indicating that high concentrations were deleterious to growth of the cultures. The changes associated with carbon and nitrogen status of the cell at elevated concentrations of MSX are also discussed


TOPSIS model is applied to the evaluation of project bid in the paper, the information entropy method is adopted in the calculation of parameter weight in order to avoid the subjectivism of fixing weight.TOPSIS model of e-valuation for project bid on information entropy is set up, the calculation method is simple, the result is rational.


As the pandemic and associated global traumas of recent years continue to reverberate through creative arts education, contributors to this issue consider the pedagogical possibilities embedded in online and in-person learning, collaborative and individual modalities, reflective and dialogic experiences, and material and spatial experimentation – suggesting that this may be a generative moment for art, design and communication in higher education.


How well do firearm markets comply with firearm restrictions? The Massachusetts Attorney General issued an Enforcement Notice in 2016 to announce a new interpretation of the key phrase "copies and duplicates" in the state's assault weapons ban. The Enforcement Notice increased assault rifle sales by 1,349 (+560%) within five days, followed by a reduction of 211 (58%) over the next three weeks. Assault rifle sales were 64-66% lower in 2017 than in comparable earlier periods, suggesting that the Enforcement Notice reduced assault weapon sales but also that many banned weapons continued to be sold.


The status offlowerindustry ,the advanteges and conditions offlowerindustry develop ment of Changchun city was analysed .The basic tragedy of flower industry development of Changchun city was discussed .


1,2,3-Triazabutadienes. XX. Investigations of the Photochemical Z-E-Isomerization, Photolysis, Protonation and Acidic Cleavage of 1-Aryl-3-3-methylbenzthiazolinyliden-(2)-triazenes in Micellar Solutions

The E-isomers of the 1-Aryl-3-[3-methylbenzthiazolinyliden-(2)]-triazenes are soluble in aqueous micellar solutions of sodium dodecylsulfate (NDS) and cetyltrimethylammoniumbromide (CTAB). They are fixed in the Stern region of the micelles. The Z-isomers decompose in aqueous micellar solutions by acidic cleavage. They can be stabilized by the use of alkaline buffer solutions. The concentration of protons is higher by the factor 103 in the Stern region of NDS-micelles than in the Stern region of CTAB-micelles. This difference is explained by electrostatic attraction and repulsion between the protons and the micelles. The quantum yields of the photochemical isomerization in micellar solutions and in organic solvents are the same. Water soluble ionic dyes with relatively low triplet energies sensitize the photoisomerization in micellar solutions and the photostationary state is on the side of the E-isomer.


The coming of network age brings new problems and challenges to university counselor work,and the thinking,learning and living mode of students becomes more complicated because of the impact of network information.In order to fulfill the duties of themselves in network age,the counselors should change traditional working mode and enhance network application-level.


Objective
We predicted the molecular mechanism of Panax notoginseng in the treatment and improvement of scar hyperplasia, by using the methods of network pharmacology and bioinformatics.

Methods
We collected of related active constituents and targets of Panax notoginseng by retrieving TCM systems pharmacology database and analysis platform (TCMSP), and collected of related active constituents and targets of scar by Genecards database and OMIM database. Cytoscape 3.6.1 software was used to construct "drugs-chemical components-targets-diseases" interaction network diagram. The protein in teraction network map (PPI) was constructed by STRING database. The key targets were used to analyze gene ontology (GO) enrichment and kyoto encyclopedia of genes and genome (KEGG) pathway enrichment.

Results
Totally 7 chemical compponents, including beta-sitosterol, quercetin, Stigmasterol and etc. and 108 targets, including AKT1, JUN, MAPK1, IL6 and ect. Panax notoginseng exerts its effects on scar mainly by acting on signal pathways, including PI3K-AKt signal pathway, MAPK signal pathway, TNF signal pathway and ect.

Conclusions
Based on the methodology of network pharmacology, this study preliminarily predicted the major targets and pathways Panax notoginseng in the treatment of scar, providing a direction for further studies.

Key words:
Panax notoginseng; Cicatrix; Network pharmacology; Target; Signaling pathway


The authors analyze the archeological, historical, botanical, cytological, geographic, molecular and reproductive biology of saffron and allied species in order to establish its site and parent origin. The authors have studied saffron, Crocus sativus and the diploid species C. cartwrightianus, C. thomasii, C. hadriaticus and compared them with what was previously known from the literature. When saffron originated is still open to dispute. It has been widely known since the pre-Hellenic and Hellenic periods, but it is impossible to detect if was C. sativus or other Crocus species such as C. cartwrightianus. Concerning the site origin the research indicates two possible sites: one in Greece in the Mediterranean area, the other at East in Turkey-Iran-India. In both areas, records and place names connected with various species of Crocus constitute an important information source for the presence of saffron. Cytological, DNA, and reproductive studies on the allied species of C. sativus such as C. cartwrightianus, C. thomasii, C. hadriaticus, indicate a more likely parent of saffron may be C. cartwrightianus or C. thomasii. Both these species are diploid with a karyotype similar to saffron. In addition, their pollen can fertilize the egg cell of saffron, giving rise to seeds which are viable, germinate and form new corms. Thus, saffron can originate through fertilization of a normal reduced egg cell with an unreduced male gamete of the same Crocus species or by crossing between an egg cell and the male unreduced gamete of another species. The origin of Saffron by allopolyploidy seems more probable considering the recent data on its karyotype and molecular biology.


A distorted spin-dependent spectral function for 3 He is considered to take care of the final state interaction in the extraction of the quark transverse-momentum distributions in the neutron from semi-inclusive deep inelastic electron scattering off polarized 3 He at finite momentum transfers. The generalization of the analysis in a Poincare covariant framework within the light-front dynamics is outlined. The definition of the light-front spin-dependent spectral function for a J=1/2 system, as the nucleon, allows us to show that within the light-front dynamics and in the valence approximation only three of the six leading twist T-even transverse- momentum distributions are independent.


Last week's [official event about The Way Ahead](http://www.connectinglondoners.blog/2017/voices-from-the-tower-may-change-tone-of-thewayahead-for) for London's civil society, organised by London Funders and their partners, was followed by a less formal


As spacecraft designs converge toward miniaturization and with the volumetric and mass constraints placed on avionics, programs will continue to advance the 'state of the art' in spacecraft systems development with new challenges to reduce power, mass, and volume. Although new technologies have improved packaging densities, a total system packaging architecture is required that not only reduces spacecraft volume and mass budgets, but increase integration efficiencies, provide modularity and scalability to accommodate multiple missions. With these challenges in mind, a novel packaging approach incorporates solutions that provide broader environmental applications, more flexible system interconnectivity, scalability, and simplified assembly test and integration schemes. This paper will describe the fundamental elements of the Integrated Avionics System (IAS), Horizontally Mounted Cube (HMC) hardware design, system and environmental test results. Additional information is contained in the original extended abstract.


Let n ∈ ℕ. An element (x1, … , xn) ∈ En is called a norming point of if and , where denotes the space of all continuous symmetric n-linear forms on E. For , we defineNorm(T) is called the norming set of T.Let be the plane with a certain norm such that the set of the extreme points of its unit ball ext for some .In this paper, we classify Norm(T) for every . We also present relations between the norming sets of and .


A risk assessment is typically required by legal regulations in production automation. These regulations vary from country to country. Risk assessment is often incomplete in industrial practice. Not all hazards are detected and risks are estimated insufficiently. Furthermore, risks are mostly assessed after the design of the product and/or production process. As result additional safety measures to reduce risks will cause higher costs and delays. This paper proposes an approach to semi-automatically derive risk from a virtual reality (VR) model of a machine. The focus is on the specific category of crushing hazard. These include situations where a human being might be hurt by being crushed. The VR model is based on a CAD model which mostly has been developed during the design phase of almost all technical products. The core idea is to identify moving parts of the machine and to calculate possible crushing zones by automatic distance approximations. The used algorithm relies on geometric CAD data. It uses axis aligned bounding volumes (AABB's) and the octree data structure. The concept is implemented in a prototype which especially determines crushing and shearing hazards and visualizes the result in the VR model for the experts. The software supports the process of risk assessment a precise and methodical approach and hardly minimizes the possibility of non-considering potential safety hazards. The prototype permits an effective, exact and methodical practice to the experts responsible in the process of the risk assessment by giving targeted advices. Furthermore, it allows the analysis of crushing hazards already during the design phase.


A liquid-core air-clad microstructured fiber has been developed for determination of ethanol concentration in aqueous solutions by Raman spectroscopy. The sensor shows a linear response and a low ethanol concentration solution has been characterized using the calibrated sensor. The configuration used for light and liquid injection is stable and robust, making the sensor useful for on-line measurements.


This paper is a qualitative urban ethnographic study of Black and Arab youth, and the effects of poverty in Seine-Saint-Denis and the 18éme arrondissement. The work concerns individual and group attitudes on 'affinity,' 'placemaking,' and 'discrimination' vis-à-vis the 2007 'Le Grand Paris' urban renewal proposal. The youth included in the study are members of two community-based organizations—Association Le Club Barbés in the 18éme, and Association Youth in Movement (Jeunesse en Mouvement-JEM) in Seine-Saint-Denis. Through Critical Discourse Analysis (CDA), direct participant observation, go-along, semi-structured, open-ended, and face-to-face interviews between 2013 and 2014, I collected 15 participant interviews and 7 expert interviews. I identified four identity-forming narratives from my participant interviews: (1) placemaking through affinity bonds; (2) schools as boundary making; (3) navigating violence between worlds; and (4) self-esteem through leadership. These narratives strongly suggest that youth participation in civic associations is correlated with a greater level of individual and group efficacy.


Recent BESIII data on radiative $J/\psi$ decays from $\sim 10^{10}$ $J/\psi$ samples should significantly advance our understanding of the controversial nature of $\eta(1405/1475)$. This motivates us to develop a three-body unitary coupled-channel model for radiative $J/\psi$ decays to three-meson final states of any partial wave ($J^{PC}$). Basic building blocks of the model are bare resonance states such as $\eta(1405/1475)$ and $f_1(1420)$, and $\pi K$, $K\bar{K}$, and $\pi\eta$ two-body interactions that generate resonances such as $K^*(892)$, $K^*_0(700)$, and $a_0(980)$. This model reasonably fits $K_SK_S\pi^0$ Dalitz plot pseudo data generated from the BESIII's $J^{PC}=0^{-+}$ amplitude for $J/\psi\to\gamma K_SK_S\pi^0$. The experimental branching ratios of $\eta(1405/1475)\to\eta\pi\pi$ and $\eta(1405/1475)\to\gamma\rho$ relative to that of $\eta(1405/1475)\to K\bar{K}\pi$ are simultaneously fitted. Our $0^{-+}$ amplitude is analytically continued to find three poles, two of which correspond to $\eta(1405)$ on different Riemann sheet of the $K^*\bar{K}$ channel, and the third one for $\eta(1475)$. This is the first pole determination of $\eta(1405/1475)$ and, furthermore, the first-ever pole determination from analyzing experimental Dalitz plot distributions with a manifestly three-body unitary coupled-channel framework. Process-dependent $\eta\pi\pi$, $\gamma\pi^+\pi^-$, and $\pi\pi\pi$ lineshapes of $J/\psi\to\gamma(0^{-+})\to \gamma(\eta\pi\pi)$, $\gamma(\gamma\rho)$, and $\gamma(\pi\pi\pi)$ are predicted, and are in reasonable agreement with data. A triangle singularity is shown to play a crucial role to cause the large isospin violation of $J/\psi\to\gamma(\pi\pi\pi)$.


Introduction: Haemophilus influenza is a type of bacterium that is non motile, gram negative and causes poisoning and infection including pneumonia,bronchitis etc. In order to study the resistivity of H.influenza protein, transcription regulator: HI0433, homology modeling is an important step to predict structure. Material and methods: Bioinformatics such as CMR, BLAST, modeller Prcheck and Prosa was carried out to find 3D structure of protein. Results and Discussion: H.influenza has 1792 proteins. Out of these, 456 hypothetical proteins were found. Homology modeling of transcriptional regulator H10994 was done it consists of 8 helices and 7 beta sheets. Ramachandran plot has shown that it consists of 95.2% particles in maximum allowed regions, 2.9 % particles in fewer allowed region, 1.4% particles in inadequate allowed region, 5% particles in disallowed region. Conclusion: By homology modeling of H. influenza, transcriptional regulator protein (HI0433), structure was designed which has provided enough information for vaccine development to control its transcription for causing disease.


References 1. Badhwar V, Alkhouli M, Mack MJ, Thourani VH, Ailawadi G. A pathoanatomic approach to secondary functional mitral regurgitation: evaluating the evidence. J Thorac Cardiovasc Surg. 2019;158:76-81. 2. Penicka M, Linkova H, Lang O, Fojt R, Kocka V, Vanderheyden M, et al. Predictors of improvement of unrepaired moderate ischemic mitral regurgitation in patients undergoing elective isolated coronary artery bypass graft surgery. Circulation. 2009;120:1474-81. 3. Goldstein D, Moskowitz AJ, Gelijns AC, Ailawadi G, Parides MK, Perrault LP, et al; CTSN. Two-year outcomes of surgical treatment of severe ischemic mitral regurgitation. N Engl J Med. 2016;374:344-53. 4. Stone GW, Lindenfeld J, Abraham WT, Kar S, Lim DS, Mishell JM, et al. Transcatheter mitral valve repair in patients with heart failure. N Engl J Med. 2018;379:2307-18. 5. Obadia JF, Messika-Zeitoun D, Leurent G, Iung B, Bonnet G, Piriou N, et al; MITRA-FR Investigators. Percutaneous repair or medical treatment for secondary mitral regurgitation. N Engl J Med. 2018;379:2297-306. 6. Grayburn PA, Sannino A, Packer M. Proportionate and disproportionate functional mitral regurgitation: a new conceptual framework that reconciles the results of the MITRA-FR and COAPT trials. JACC Cardiovasc Imaging. 2019;12:353-62. 7. Nappi F, Spadaccio C, Nenna A, Lusini M, Fraldi M, Acar C, et al. Is subvalvular repair worthwhile in severe ischemic mitral regurgitation? Subanalysis of the papillary muscle approximation trial. J Thorac Cardiovasc Surg. 2017;153: 286-95.e2. 8. Nappi F, Lusini M, Spadaccio C, Nenna A, Covino E, Acar C, et al. Papillary muscle approximation versus restrictive annuloplasty alone for severe ischemic mitral regurgitation. J Am Coll Cardiol. 2016;67:2334-46. 9. Bothe W, Timek TA, Tibayan FA, Walther M, Daughters GT, Ingels NB Jr, et al. Characterization of 3-dimensional papillary muscle displacement in in vivo ovine models of ischemic/functional mitral regurgitation. J Thorac Cardiovasc Surg. 2019;157:1444-9. 10. Mihos CG, Capoulade R, Yucel E, Xydas S, Nappi F, Williams RF, et al. Mitral valve and subvalvular repair for secondary mitral regurgitation: rationale and clinical outcomes of the papillary muscle sling. Cardiol Rev. 2018;26:22-8. 11. Timek TA, Lai DT, Tibayan F, Liang D, Daughters GT, Dagum P, et al. Ischemia in three left ventricular regions: insights into the pathogenesis of acute ischemic mitral regurgitation. J Thorac Cardiovasc Surg. 2003;125:559-69. 12. Nappi F, Nenna A, Spadaccio C, Lusini M, Chello M, Fraldi M, et al. Predictive factors of long-term results following valve repair in ischemic mitral valve prolapse. Int J Cardiol. 2016;204:218-28.


PROBLEM TO BE SOLVED: To increase a performance of a raster picture processor. SOLUTION: A picture printed in a hard copy such as a sheet, microfilm, and photographic film is designated in page describing language. A raster picture processor for converting a page describing language data stream into bit map expression normally converts an original data stream into an intermediate data stream at first. This converting process is handled in parallel by several processors by the proper partitioning of the original data stream and the inclusion of a control command.


Sericultural and Agri-Food Research Instit Sciences, Key Laboratory of Functional Fo Affairs, Guangdong Key Laboratory of Agricu College of Light Industry and Food, Z Engineering, Guangzhou, Guangdong 51022 Modern Agriculture Research Center, Z Engineering, Guangzhou, Guangdong 51022 Department of Food, Wine and Molecu Christchurch, New Zealand † Electronic supplementary informa 10.1039/c9ra02523e Cite this: RSC Adv., 2019, 9, 16007


To determine the acute and follow-up effects of 4 months of health and fitness education with and without exercise training, 182 sedentary, obese. 60− to 70-year-old women were randomly assigned to the following groups: fitness education (ED. n - 70). fitness education with aerobic training (EX. n = 76), and control (CO. n = 36). Assessments of aerobic power using a submaximal bicycle test, body composition, using the sum of three skinlfolds. and body mass index (BMI) were made before and after the 4-month intervention and at a 3− and 6-month follow-up. Both EX and ED decreased body fat levels (vs. CO) over the course of the study (p


The accidents are mainly created by the people's unserviceability action.The harmfulness of some facors are discussed through example analysis.Meanwhile,the prevention measures are expounded from the whole enterprise consideration to forming own safety culture and raising workers safety quality.


Luteal function in Pine Marten (Martes foina), species which exhibit delayed implantation, shows low progesterone plasma levels during the major part of diapause. A significant increase occurs before implantation. These results confirm histological appearance observed in lutea corpora.


The mechanism of action of aspirin (ASA) is related to cyclooxygenase (COX) inhibition, but additional actions cannot be excluded for their antiinflammatory properties and antithrombotic activity. In the current investigation, we examined the effects of ASA on COX and 5‐lipoxygenase (5‐LO) pathways and its impact on peroxisome proliferator‐activated receptor α (PPARα) and cytokine‐induced neutrophil chemoattractant‐1 (CINC‐1) levels in rat liver cells. In Kupffer cells, the liver resident macrophages, ASA switched eicosanoid biosynthesis from prostaglandin E2 (PGE2) to leukotriene B4 (LTB4) and 15‐epi‐lipoxin A4 (15‐epi‐LXA4) formation. In hepatocytes, ASA significantly inhibited PPARα protein expression and CINC‐1 secretion, effects that were also observed in hepatocytes exposed to the selective PPARα agonist Wy‐14643. In contrast, treatment of hepatocytes with PGE2 in association with LTB4 had no significant effect on PPARα but stimulated CINC‐1 release. Interestingly, the endogenous antiinflammatory eicosanoids LXA4 and ASA‐triggered 15‐epi‐LXA4, in addition to inhibiting macrophage 5‐LO activity to a similar extent as PGE2, significantly reduced PPARα and CINC‐1 levels in hepatocytes. Taken together and because arachidonic acid‐derived products, PPARα levels, and CINC‐1 secretion are involved in the extent and duration of an inflammatory response, these findings provide additional molecular mechanisms for the pharmacological properties of ASA.


We present a hardware architecture of a heapsort algorithm, the sorting is employed in a subband coding block of a wavelet-based image coder termed Öktem image coder [1]. Although this coder provides good image quality, the sorting is time consuming, and is application specific, as the sorting is repetitively used for different volume of data in the subband coding, thus a simple hardware implementation with fixed sorting capacity will be difficult to scale during runtime. To tackle this problem, the time/power efficiency and the sorting size flexibility have to be taken in to account. We proposed an improved FPGA heapsort architecture based on Zabołotny's work [2] as an IP accelerator of the image coder. We present a configurable architecture by using adaptive layer enable elements so the sorting capacity could be adjusted during runtime to efficiently sort different amount of data. With the adaptive memory shutdown, our improved architecture provides up to 20.9% power reduction on the memories compared to the baseline implementation. Moreover, our architecture provides 13x speedup compared to ARM CortexA9.


In this article, methodologists - scientists who have devoted their work to the educational essence of history lessons, moral and patriotic education, pay special attention to the formation of a sense of patriotism, consider effective ways and methods of its organization. In the implementation of the tasks of patriotic education, the place of the subject of the history of Kazakhstan taught at the school is determined and determined by the following methodological conditions. In the methodological works, taking into account the methods and techniques that have an educational impact on students in teaching history, it was found that the use of the following methodology in the experimental class is effective. The results of the experiment showed the effectiveness of using the possibilities of active teaching methods and innovative technologies that have an educational impact on students in teaching the history of Kazakhstan. In the experimental group, materials were selected that have an educational impact on students in teaching the history of Kazakhstan, make them think, evaluate, and on the basis of which historical facts, ideas, clear, concrete facts, and influence the feelings of students give rise to certain ideas and beliefs. The influence of such selected facts has shown that the more students think and reflect, the stronger the effect. In the course of research, guided by these recommendations, we were convinced of the need for continuous improvement of active methodological approaches to patriotic education.


We demonstrate the 1.35‐μm emission at room temperature from wire‐like anisotropic InGaAs quantum dots (QDs) grown on GaAs (001) substrate by atomic layer epitaxy technique. The QD formation has been carried out in ranges of In composition of x=0.23–0.5 and equivalent thickness of teq=2.5–25 monolayers (MLs). As InGaAs coverage and growth temperature increase, the QD distribution gradually evolves from isolated dots to wire‐like structure aligned to a preferential direction of [1–10]. The photoluminescence emission of 1.35 μm and the full width half‐maximum (FWHM) of 25 meV have been achieved from InGaAs QD with x=0.5 and teq=7.2 MLs.


This article presents several examples of corporate communications networks designed to utilize the ultra-high-speed and broadband services that will be provided under the PHOENIX Project. Based on these examples of user systems, it discusses the purposes for increasing the speed and bandwidth of corporate communications networks, the costs involved and the benefits to be gained.


The article presents an efficient parallel logic-circuit simulation scheme based on the Time Warp optimistic algorithm. The Time Warp algorithm is integrated with a new global virtual time (GVT) computation scheme for fossil collection. The new GVT computation is based on a token ring passing method, so that global synchronization is not required in a shared-memory multiprocessor system. This allows us to process large logic simulation problems, where the GVT computation is executed frequently for fossil collection due to limited memory space. We also present how to reduce the frequency of the GVT computation and the rollback radio by scheduling the process with the smallest timestamp first. We implement the parallel logic-circuit simulator using the Time Warp on BBN Butterfly machines, and the experimental results show that the algorithm provides a significant speedup in processing time, even for very large circuits.<<ETX>>


Context: The overall scientific community is proposing measures to improve the reproducibility and replicability of experiments. Reproducibility is relatively easy to achieve. However, replicability is considerably more complex in both the sciences and Empirical Software Engineering (ESE). Several strategies, e.g., replication packages and families of experiments, have been proposed to improve replication in ESE, with limited success. We wonder whether the failures are due to some mismatch, i.e., the researchers' needs are not satisfied by the proposed replication procedures. Objectives: Find out how experimental researchers conduct experiments in practice. Methods: We carried out an ethnography study within a SE Research Group. Our main activity was to observe/approach the experimental researchers in their day-to-day settings for two years. Their preferred literature and experimental materials were studied. We used individual and group interviews to gain understanding and examine unclear topics in-depth. Results: We have created conceptual and process models that represent how experimentation is really conducted in the Research Group. Models fit the community's procedures and terminology at a high level, but they become particular in their minute details. Conclusion: The actual experimental process differs from textbooks in several points, namely: (1) Number and diversity of activities, (2) existence of different roles, (3) the granularity of the concepts used by the roles, and (4) the viewpoints that different sub-areas or families of experiments have about the overall process. © 2011 Published by Elsevier Ltd.


The invention relates to a method for extracting and refining paeonia rockii seed oil. The method comprises the following steps: collecting seeds, unshelling, baking and frying, carrying out screw press, filtering, deacidifying, degumming, drying, decoloring, deodorizing in vacuum, adding an antioxidant and filling. After solid impurities and residues obtained by the screw press are broken up, ethylacetate is added, then refluxing extraction is carried out, and a solvent is recovered so as to obtain the paeonia rockii seed oil for cosmetics. A two-step method is used for extracting the paeonia rockii seed oil, wherein in the first step: primary pressed oil used for eating is obtained by physical pressing, and the produced paeonia rockii seed oil has higher oil recovery rate and no residual solvents and can be securely eaten; in the second step, the ethyl acetate is adopted for extraction, and ingredients for antioxidation, inflammation resistance, sun block, and the like in the paeonia rockii seed oil can be extracted and used for producing the cosmetics. The invention not only improves the oil recovery rate of paeonia rockii seeds, but also ensures that the effective ingredients in the paeonia rockii seeds are sufficiently utilized.


The author presents one pulmonary agenesia case vhese hystory
is as follows: A child, normal aspects, 1 month and 9 days old; birthweight
3.200 gr., size 51 cm.; faetus-placentary relation 6:1; norma
1 amniotic liquid and placenta; normal parturition: 14 hours 10 minutes. Mother 34 years old, seconddiparus, with rino-faringeus afeetions frecuentely.
In the last months of her gestation was albumina vestigious; maximun
tension, 16 (Pachon), rapidely resigned by treatment. Wassermann
negative. During her puerperious time, nipple fissure, labial
herpes, and 18 days after linfangitis in the left breast cured perfectely.
(Her first son he was born dead.).
The child's personal antecedents as follow: Mother's milk Iactation
during the first 23 days, weighting at end 3.250 grs. Ten days
latter, vomits and alvine evacuation undone and obscure colour. He
ta kes supplementary cow-milk bottles.
Three days after, temperature 38,5, without symptoms notorious.
The sequent day, at 8 a. m., temperature 38,7. No rinitis, faringitis
nor tirage. Dyspnea without polypnea. Normal cardiac tones. Percution:
slight submassive in the right posteriour plane. Auscultation:
several gross battle diseminated.
Treatment: revulsives, oxygen, coramine, cafeine. At 9 the child
dead.
NECROPSIA. - Thorax: right lung:s swifty hipertrofiated with full
brochopneumon•e damages. The midlobule coverihg to the heart and
both together occuping part of the left thoracic cavity. The left lungs
very little adhereded to the parietal pleura in all the external and
diafracmatic face extension; free in the vertebral canal anteriour border.
The left bronchia magnitude is equivalent to the third Part of
the right side. Timo:- normal. Abdominal Cavity: Liver weight 160
grs.; Spleen weight 15 grs.; the restant visceraes normal.
The rapid death of the child without to arrive at the hepatization
of the rigt lung, can be explained by the insuficient respiratory zone
of the left lung, imposibiliting a good hematosis, previously supplied
by the hiperfunction of the right lung swiftly hipertrofiated.
By not appreciating anything anormal by auscultation and percussion
at the left side, could be explained, because, part of the right
lung recovered the heart and altogether occupied the left pleural cavity,
and the parietal skeleton (not deformed), would serve of conductor
of sonorus vibrations, transporting them through the opposed hemythorax
being able to difer only by its intensity. This symptoms was
neglected at the child's exploration.
We could have thogut this case as a spontaneous pneumothorax
with retraction of the lungs by the adhesions, but we believe it is not
for the simple reason as follows: zhow cauld we explained the fact
that the heart and the opposed lung, occupied in part the left pleural
cavity?. Neither the evident fact of the presentation of the left lung
smaller than the dight.
It only rest to consider that the adhesions, from the macroscopic
point of view, seem having long held place and that every adhesion
supposes an anteriour flogistic process; perhaps by this method we
could explain the hypogenesia as an effect of ene intrautherine pleuresie
at the period in which the lung, notwithstan.ding justly formed,
was not developed.
It is deplorable not to have a breast radiagraphy of this child, because
it would give a clearest idea of the pulmonar situation.


Vol. 14, No. 2, June, 2019 ISSN: 0973-4155 ECO CHRONICLE PP: 160 166 RNI No. KERENG/2006/19177 Landslide susceptibility analysis, a precursory stage in landslide hazard and risk assessment was carried out in the study using geospatial techniques. Malappuram district which consist of highly undulating terrains including ecologically sensitive segments of Western Ghats selected for the analysis. Five major Landslide influencing factors such as geology, geomorphology, slope, soil and landuse/landcover were delineated in the ArcGIS platform and generated suitable weights for each of these factors based on their influence on landslide occurrence. The resultant susceptibility analysis pointed out that the 13.46 % of the total area is the most landslide vulnerable and about 17%, 3% and 66% were contributes unstable, moderately stable and highly stable terrain respectively. The prediction accuracy ensured through the validation analysis using recent landslide occurrence and resultant map will enable to reduce the future landslide hazards in zone through the appropriate and adaptive land use planning and innovative management


The rates of oil biodegradation, as judged by oxygen uptake, were com-pared at 14 and 4 °C, under conditions of continuous replenishment of nitrogen and phosphorus without high concentrations of either. A value of 2.7 was obtained for Q'10 (the ratio of oxidation rates at 14 and 4 °C per unit nitrogen uptake). This agrees with figures for Q10 quoted for enriched culture conditions. The uptake of nitrogen and phosphorus was not reduced very markedly at lower temperatures and it is considered that nitrogen supply controls the rate of oxidation at 4 °C as it did at 14 °C. On this basis, tentative estimates of the biodegradative capacity of local seawater are made.


The idea that the body must and can protect itself from the hidden dangers of the outside world—microbes and poisons—and that it can learn from the experience and do it better next time has been recognized for thousands of years. During the plague of Athens, Thucydides had noticed that those who had recovered showed the most compassion for the sick. Since they knew that the same person was never struck a second time, they did not fear for themselves. King Mithradates VI of Pontus took small doses of poisons and noxious substances repeatedly to protect himself against fatal poisoning later, an idea clearly related to the modern idea of acquired immunity. Here is A. E. Housman's wonderful account in his poem (A Shropshire Lad, LXII, Terence this is stupid stuff): There was a king reigned in the East: There, when kings will sit to feast, They get their fill before they think With poisoned meat and poisoned drink. He gathered all that springs to birth From the many-venomed earth; First a little, thence to more, He sampled all her killing store; And easy, smiling, seasoned sound, Sate the king when healths went round. They put arsenic in his meat And stared aghast to watch him eat; They poured strychnine in his cup And shook to see him drink it up: They shook, they stared as white's their shirt: Them it was their poison hurt. —I tell the tale that I heard told. Mithradates, he died old.


Synopsis: Continuing on from part one, this article describes different fabrication processes of Nb3Sn wires. The PIT process using Nb-Sn compound powder, Ta-Sn powder and Cu5Sn4 powder has been commercialized. The Nb tube process, originally developed in Japan, has been recently revived in US. A MJR process using Nb mesh sheet has been also developed. The Nb3Sn wires fabricated through these processes show nearly the same high non-Cu Jc at 12 T as that of the RRP internal Sn processed wire described in the last article. The JR Nb3Sn wires using Sn-based alloy sheet indicate enough potential to be used in fields over 20 T at 4.2 K. The stoichiometric Sn concentration and the homogeneous grain structure are the key factors to produce high performance in the Nb3Sn layers. In addition Nb3Sn wires with ultra-thin filaments have been developed for AC use. In the study of V3Ga wires, pioneering works have been performed, such as the effect of Cu for the synthesis of A15 layer, which yielded a breakthrough in the wire fabrication. The V3Ga wires have also been used for high-field superconducting magnets. Further progress may be expected in the processing and performance of these compound wires based on the informations obtained so far.


Nonsuicidal self-injury (NSSI) is one of the strongest predictors of suicidal behavior. Despite this, the field still has a limited understanding of the mechanisms by which this relationship is conferred. As there has been a proliferation of research in this area over the past decade, an updated systematic review of the empirical research examining potential factors driving the relationship between NSSI and suicide-related outcomes is needed to move the field forward. We identified only 18 studies examining moderators or mediators of the relationship. Research to date does little to improve our understanding of the robust, prospective relationship between NSSI and suicide outcomes, highlighting a foundational gap in both the empirical and theoretical literature. Thus, we propose the Nonsuicidal to Suicidal Self-Injury Pathway Model, an expanded theoretical model of this relationship drawing on extant theory and empirical research, as well as discuss future directions for work in this area.


With the rapid growth of the e-commerce market, Amazon.com, INC. (Amazon) is one of remarkable firms. The general financial condition is worth analyzing to observe how Amazon makes money, and how it operates. Yahoo Finance and Macrotrends, which are platforms to search for financial and stock information of published companies, are main data resource websites in this article. Also, the financial report of Amazon is a channel to get detailed information and data. This paper mainly uses Price-to-Earnings Ratio (P/E ratio), which gives a brief view to show the anticipation of the company itself and the market based on analyzing stock prices. By comparing Amazon and its comparable firms' data from 2019 to 2020, the stock price of Amazon is overvalued. The author forecasts that this trend will be continued, but the company faces both opportunities and challenges. This article provides investors and those interested in e-commerce or Amazon with a reference for present and future value of Amazon.


Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and is one of the most common cancers worldwide, with over 80% of cases diagnosed in developing countries in sub-Sahara Africa and Southeast Asia (1). In the United States alone, HCC incidence has more than tripled over the past three decades due to an increased prevalence of liver cirrhosis, which is the major risk factor for HCC.


The central thesis of this book is that the political history of the Dutch state is closely intertwined with the control over the sea and the estuaries of the rivers Rhine and Meuse. This is of course not a very original thought, 'polderen' is generally seen as a second nature of Dutch politics, and the continuity in the structure of the polder districts over the centuries, and its impact on Dutch public administration is unprecedented in the western world.


Chapter 10 addresses how religious disagreement, like disagreement in science, stands to deliver important epistemic benefits. But religious communities typically think believers should be loyal to God; and since engaging with religious disagreement opens oneself to considering negative beliefs about God, doing so is disloyal. The chapter discusses two arguments that aim to show that religious disagreement is typically disloyal. It then argues that religious disagreement is not typically disloyal, and can in fact be loyal. Finally, the chapter argues for a superior form of loyalty that is epistemically oriented: concerned with knowing the other party as she really is.


Women regularly endure sexist microaggressions, which are often associated with anger, depression, anxiety, low self-esteem, and trauma. The cumulative effects of sexist microaggressions may result in internalized sexism and undermine self-compassion. Notably, prolonged exposure to sexism is associated with trauma symptoms; however, the traumatic effects of sexist microaggressions have remained largely theoretical. Thus, we examined the role of sexist microaggressions as a traumatic stressor and evaluated self-compassion and internalized misogyny as mediators of sexism-based traumatic stress. With a sample of 370 adult cisgender women, results suggested that sexist microaggressions significantly and positively predicted trauma symptomology, and that this relationship was partially mediated by self-compassion but not internalized misogyny. Results supported sexism as a traumatic stressor, and low self-compassion as a mechanism through which sexist microaggressions result in traumatic stress. We discuss implications for research and practice.


Abstract- Aim and Objective- Anal fistula is a condition which has been recognized as a difficult surgical disease in all the ancient [1] and modern medical sciences of the world. The approach to the treatment for a single disease is only suggestive of the fact that none of these methods is satisfactory. 'Ksharsutra' is being used successfully in the management of anal fistula [2], but in the case of High Anal / Horse Shoe Fistula particularly it is not convenient as size of wound is big which increases duration of therapy and hospitalization and ultimately on cost of thera-py. To overcome all these problems, partial fistulectomy with 'Ksharsutra' is the ray of Hope. Material and Methods- Patients are recruited from Shalyatantra OPD after confirmed diagnosis. Ethical guidelines of ICMR for human re-search were strictly followed. Results and Discussion- All Patients were diagnosed, investigated and after physical fitness under spinal anesthesia, Partial Fistulectomy with 'Ksharsutra' was carried out. 'Ksharsutra' was changed on weekly basis & patients were observed for parameters during this weekly fol-low-up for 12 weeks. All observations were recorded in the Case record Form. All study data was analyzed by applying Students Paired't'testand significance 'P' value calculated for individual symptoms.


In this paper we presented technical study and security assessment that may threat the Arabic Domains in the new proposed multilingual domains (International domain Names IDN). We analyzed the Unicode Script (in particular the Arabic Scripts) and showed how vulnerable the proposed solution will be, then we presented suggestions for improved solution to be adapted to avoid future security risk when using the Arabic Domain names.


The persistence and dissipation kinetics of trifloxystrobin and tebuconazole on onion were studied after application of their combination formulation at a standard and double dose of 75 + 150 and 150 + 300 g a.i. ha−1. The fungicides were extracted with acetone, cleaned-up using activated charcoal (trifloxystrobin) and neutral alumina (tebuconazole). Analysis was carried out by gas chromatograph (GC) and confirmed by gas chromatograph mass spectrometry (GC-MS). The recovery was above 80% and limit of quantification (LOQ) 0.05 mg kg−1 for both fungicides. Initial residue deposits of trifloxystrobin were 0.68 and 1.01 mg kg−1 and tebuconazole 0.673 and 1.95 mg kg−1 from standard and double dose treatments, respectively. Dissipation of the fungicides followed first-order kinetics and the half life of degradation was 6–6.6 days. Matured onion bulb (and field soil) harvested after 30 days was free from fungicide residues. These findings suggest recommended safe pre-harvest interval (PHI) of 14 and 25 days for spring onion consumption after treatment of Nativo 75 WG at the standard and double doses, respectively. Matured onion bulbs at harvest were free from fungicide residues.


Objective To observe the cell proliferation,morphology change and count number change of the A549 cells under the arsenic trioxide(As2O3) induction.Methods The A549 cells were cultured into logarithmic growth phase in vitro,and the cells were divided into experimental group and blank group.As2O3 was added into experimental group,the apoptosis status of the cells was observed under light microscope and by electron microscope scanning.The flow cytometer was used to count the cell number and calculate the change of the apoptosis ratio.Results Under the light microscope,the experimental group cells were deflated,and turned into a circle,the transmissivity decreased,and the vacuolus changes were detected in the cell body.After fluorescent staining by the acridine orange(AO),the fluorescence intensity and density of the attached cells decreased,part of the cells broke apart,nuclei disappeared,and the cell apoptosis appeared.Under the electron microscope we saw karyopyknosis,karyorrhexis,lose nuclear membrane,chromatin margination,and also the apoptotic body.The count number indicated that the apoptotic ratio(14.497%)of the experimental group was higher than that(0.027%)of the blank group(χ2=18.447,P0.0001).Conclusion Inducted by As2O3,the proliferated and apoptic changes appeare conclusively in A549 cells with an increase in the number of apoptic cells,suggesting that As2O3 might be a new option in treatment of lung adenocarcinoma.


The flowing irrigation creates many different cultural phenomena. The babao irrigation canal in Chang Hua County is one of three old irrigation canal systems in Taiwan. Therefore, irrigations and rural sceneries are elements that build extraordinary views in Chang Hua County. In the past, farmers and irrigation were closely linked to each other. The government controlled farmers via Taiwan Joint Irrigation Association. At this phase, government had full right to control the power. Due to the fast social changes and economic structure of agriculture, the range of this career has declined gradually. Taiwan Joint Irrigation Association is positively developing a style that is heading to a multi-angle changing of industries. Therefore, due to the emphasis of LOHAS (Like of Healthy and Sustainability) in recent years, it turns irrigations which were abandoned before becoming the leisure spaces with the combination of nature and manpower. People share the water power among each other. This change not only increases benefits of the running of agriculture, but also integrates indirect benefits of the ecology and living function. It has a great influence on the local area. This study takes babao irrigation canal, Ershuei Township in Chang Hua County as the object. Ershuei Township is the head of the babao irrigation canal. For the long time, local people have different interaction with irrigations. Thus, it builds many abundant and various irrigation spatial culture. This study will observe this cultural specialty through documents and interviews. Also, it will review delicately how Taiwan Joint Irrigation Association builds relationship with farmers through the sharing rights of public legal person. By using spatial production, life and ecology given by irrigation, this study also probes into how Taiwan Joint Irrigation Association controlled irrigation space and formed the political power during the time of agricultural irrigation. However, this power was shifted with the flowing of water. Taiwan Joint Irrigation Association not only depends on the limited subsidies, but also cooperates with political policy to beautify the environment along the roads of irrigations and preserve the ecology. The subordinate workstations adopt and maintain the public facilities in Ershuei Township by themselves and beautify the environment. Besides, the modernized bike ways gradually become the extraordinary life landscape. Through the control and shift of water spatial power in Ershuei Township, it causes different body experience between space and person during different phases. The final goal is to probe into how the spatial existence forms with the interaction between people and irrigation in Ershuei Township through the process from domination to sharing of the irrigation space.


laboratory animals. The use of these model systems in oncological research, e.g. in evaluating the efficacy of chemotherapeutic agents in preclinical trials as well as in clinical situations requires that morphology and function of the tumors growing in the xenogeneic host correspond with that of the tumors growing in the xenogenic host correspond with that of the original tumor. Tumors of the human urogenital system retain their morphological and karyological characteristics following xenotrans plantation as seen by virtue of light and electron micros copy. The production of erythropoeitin and human plasma proteins by renal cell carcinomas, of prostate-specific acid phosphatase by prostatic carcinoma and of HCG -ß by none-seminomateous testicular tumors grown in nude mice, clearly indicates that some functio nal characteristies of the original tumors are not influen ced by the xenotopic maintainance of these tumors. There are only a few reports comparing the isozyme profile, metabolic characteristics and growth behavior of xenotransplants with that of the original human tumor. In addition to investigations concerned with the


Summary.  For a binary treatment ν=0, 1 and the corresponding 'potential response'Y0 for the control group (ν=0) and Y1 for the treatment group (ν=1), one definition of no treatment effect is that Y0 and Y1 follow the same distribution given a covariate vector X. Koul and Schick have provided a non‐parametric test for no distributional effect when the realized response (1−ν)Y0+νY1 is fully observed and the distribution of X is the same across the two groups. This test is thus not applicable to censored responses, nor to non‐experimental (i.e. observational) studies that entail different distributions of X across the two groups. We propose 'X‐matched' non‐parametric tests generalizing the test of Koul and Schick following an idea of Gehan. Our tests are applicable to non‐experimental data with randomly censored responses. In addition to these motivations, the tests have several advantages. First, they have the intuitive appeal of comparing all available pairs across the treatment and control groups, instead of selecting a number of matched controls (or treated) in the usual pair or multiple matching. Second, whereas most matching estimators or tests have a non‐overlapping support (of X) problem across the two groups, our tests have a built‐in protection against the problem. Third, Gehan's idea allows the tests to make good use of censored observations. A simulation study is conducted, and an empirical illustration for a job training effect on the duration of unemployment is provided.


Purpose: To present a combined interventional radiologic and resection technique for the management of a large amblyogenic, highly vascular lesion of the lower eyelid associated with severe mechanical ectropion, conjunctival pyogenic granuloma, and recurrent, spontaneous conjunctival bleeding. Methods: Preoperative selective embolization and coil placement were followed by resection of the tumor. Results: Embolization, coil placement, and resection were uneventful with cosmetic and functional visual improvement obtained. Pathology indicated a noninvoluting congenital hemangioma. Conclusions: To the authors' knowledge, this is the first surgical technique reported in the ophthalmic literature for the selective embolization of a noninvoluting congenital hemangioma prior to its resection. Such a technique should be considered in the management of large lesions of this type.


— Monolayer graphene grown epitaxially (epitaxial graphene) on silicon carbide (SiC) is the best graphene material for the application of quantum Hall resistance standards (QHRS). The quality of epitaxial graphene is critical for the performance of QHRS with accuracy of ≈ 1×10 -9 . In this paper, we will characterize the morphology-related defects (multilayer graphene domains and substrate terraces) in epitaxial graphene quantitatively by confocal laser scanning microscopy (CLSM) and Raman spectroscopy. We will correlate the characteristics parameters (size and density of multilayer graphene domain, layer number of graphene, size of terraces) to the performance of graphene QHRS. Understanding the influence of scattering at the morphology-related defects in epitaxial graphene will help further improve the morphology of epitaxial graphene to enhance the performance of graphene QHRS.


A variety of combustion waste feedstocks rich in either calcia (CaO) or silica (SiO 2 ) were combined and tested in a hydrothermal synthesis experiment to investigate the precipitation of crystalline calcium silicate hydrate (CCSH) phases or Al-substituted CCSH phases. Three binary mixes were tested at three different time steps with two different mix conditions. The results show that after 7 days, the samples with a higher pH generated more hydrate phases. Many of the samples also formed calcium silicate hydroxide hydrate phases, which can be a precursor to CCSH formation.


An article in VINE 91, June 1993, dealt with the lEE's use of CAIRS‐LMS for serials management. This article treats their inter‐library loans operation. Prior to using the CAIRS module, ILL administration was purely manual; due to an increase in volume of requests, it was decided to automate. It was preferable to use a system which was integrated with the other IEE library modules so the choice of CAIRS was without question. The increasing integration of ILL with the other modules is welcomed by the library.


Objective To study variations of plasma sE-selectin and sICAM-1 level of type 2 diabetes(T2DM) patients complicated with lower limb vascular disease,and contribution of these molecules to the formation of the lower limb vascular disease. Methods Plasma sE-selectin and sICAM-1 of 51 type 2 diabetic patients and 20 age sex matched non-diabetes people(control group) were determined with ELISA.16 T2DM patients without lower limb vascular disease and 17 age sex matched T2DM complicated with lower limb vascular disease were selected from the patients group,as group 1 and group 2 respectively,and 17 age and sex matched non-diabetic individuals were selected from control group as group 3.sE-selectin and sICAM-1 level were contrasted among the three groups. Results Levels of FPG,2 h PG,HOMA-IR,sE-selectin and sICAM-1 of diabetic group were significantly elevated than those of the control group(P0.01).sE-selectin and sICAM-1 levels were no significance between group 1 and group 2(P0.05).FPG and 2 h PG in group 1 and group 2 were markedly higher than that in group 3(P0.01).Level of FINS of group 3 was higher than that of group 2 and group 1,but only had significance with group 1(P0.05).sE-selectin of group 1 was markedly higher than that of group 3(P0.01),and sICAM-1 of group 1 and group 2 were markedly higher than that of group 3(P0.05).Logistic multiple regression analysis showed that age,systolic pressure and LDL-C were risk factors for the lower limb vascular disease in T2DM. Conclusion Plasma sE-selectin and sICAM-1 of T2DM are higher than that of non-diabetic individuals,which implies that endothelial dysfunction happens in T2DM.Both T2DM patients with and without lower limb vascular disease have endothelial dysfunction.The roles of adhesion molecules may be more active before the occurrence of lower limb vascular disease in T2DM,and age,systolic pressure and LDL-C are risk factors for the lower limb vascular disease in T2DM.


Students graduating from hospitality colleges are very excited about the idea of venturing into entrepreneurship which may be because of the glamour of the hospitality industry or they want to make more money in short time. Moreover due to the demanding nature of jobs in the hospitality industry, students tend to explore allied options. Entrepreneurship is one of these options that students are inclined to. Most of the colleges are trying to fill educational gap by giving real life experiences to the students by organizing activities which enhances the entrepreneurial skills of the students. This study is aimed at analyzing the perceptions of students towards entrepreneurship & the role of hospitality colleges of Pune in developing their entrepreneurial skills. In an effort to do so, a survey in the form of a questionnaire and interviews was conducted from the sample comprising of hospitality students in Pune to understand their views on the subject. The responses received were represented graphically and analyzed using basic tools. The findings of the research suggests that most of the students want to be entrepreneurs in future and agree to the fact that formal education is necessary to be successful in the same and amongst the various entrepreneurship development activities carried out by the hospitality colleges, "Organizing Trainings & Field visits" and "Creating entrepreneurial opportunities" are the most effective ones.


This paper addresses the needs of the septic tank pumper. Historically the pumpers themselves have been responsible for those wastes they put into their tank trucks. For years a high percentage of these wastes have been deposited upon the land. Not always for its beneficial reuse – usually just for disposal, and sometimes under some permitting scenario but often under no regulatory oversight at all. With the promulgation of the Federal 40 CFR Part 503 regulations in 1993 a movement began towards legitimate beneficial reuse of septage, but progress has been slow. Today 'illegal' (at least not permitted) land application of septage and grease trap wastes accounts for more gallons disposed than many want to admit.


Design and characterization of a new inductively driven wireless coil (WLC) for wrist imaging at 1.5 T with high homogeneity operating due to focusing the B1 field of a birdcage body coil.


Due to the profound impact of multi-cultural ideas,as the main image in the local novel of new era,the farmer images' aesthetic characteristics and cultural connotation is thriving. In accordance with its own difference of aesthetic connotation,the farmer image genealogy is mainly made up of the culture-based,reality-based and survival-based images. The culture-based comes from writers' strong demand of cultural reconstruction and criticism,which has become an apparent culture signifier. The reality-based reflects the change and shape of farmers' traditional cultural psychology. The conflicts between farmer and land become writers' narrative focus. The survival-based gives prominence to farmer's survival awareness and highlights the freely rural mentality and self-sufficient survival principle,which antagonizes the assimilation and rehabilitation of ideology to the rural. With the change of cultural contexts,the farmer image genealogy and cultural connotation is bound to generate a new quality. Meanwhile,the writer must face the problem to overcome the shortcomings of farmer narrative.


I. Introduction II. Biosynthesis of TRH and Other pro-TRH-Derived Peptides A. Biosynthesis and processing of pro-TRH B. Intracellular sites of pro-TRH processing C. Tissue-specific processing of pro-TRH D. The role of PCs and CPs E. Neuropeptide and catecholamine regulation of Pro-TRH biosynthesis and processing F. Glucocorticoids modulate the biosynthesis and processing of pro-TRH G. Leptin regulates pro-TRH biosynthesis III. Function of TRH A. The HPT axis B. Extrahypophysiotropic TRH IV. Function of non-TRH pro-TRH-Derived Peptides A. prepro-TRH160–169 (pST10) B. prepro-TRH178–199 (pFE22) C. prepro-TRH178–185 and prepro-TRH186–199 (pFQ7 and pSE14) D. prepro-TRH53–74 (pFT22) E. prepro-TRH83–106 (pEH24) and prepro-TRH208–255 F. TRH-Gly V. Non-TRH pro-TRH-Derived Peptides Outside of the CNS VI. TRH and Other pro-TRH-Derived Peptide Receptors A. The TRH receptor B. The prepro-TRH160–169 (pST10) receptor VII. TRH Degradation VIII. Concluding Remarks


The present invention relates to a method for planning an ultrasound guided biopsy of at least one region of interest in an organ comprising the steps of: a) obtaining backscattered 2D or 3D ultrasound data of a region of the organ, b) identifying one or more regions of interest in said three-dimensional volume using a first processor configured to analyze said 2D or 3D volume data, c) selecting in said first processor the characteristics of at least one ultrasound transducer suitable for the guidance of the biopsy comprising a biopsy needle, d) registering the transducer's characteristics selected in step (c) with the identified region of interest of step (b) using said processor, e) generating at least one biopsy scan plane image using the results of the registering step (d); and f) indicating on said simulated scan plane image the identified region of interest and at least one simulated needle trajectory. The present invention also relates to a method for performing ultrasound guided biopsy.


The objective of this study was to determine the difference b tween summer and winter in blood composition at the time of slaughter and meat quality of beef steers. Fifteen steers in summer (18.9 28.4'C) and 20 steers in winter (4.9 7.04C) were transported to the nearest commercial slaughterhouse by truck. Mer an overnight lairage in the holding pen in the slaughterheuse, the steers were slaughered individually. Plasma cortisol and blood glucose concentrations were significantly higher in summer than in winter (both P < O.O1). Serum pH and serum total protein cencentration were significantly lower in summer than in winter (both P < O.Ol). These results suggest a severer condition for steers in summer, which should be mainly caused by water deprivation the night before slaughter. Serum NEFA concentration (P < O.O1), and AST and ALT activity (both P < O.05) were significantly higher in winter than in summer. The main cause of these physiological responses should be fbod deprivation the night befbre slauglrter. However, these physiological responses of steers did not have much effbct on meat quality. In addition the frequency of human handling during loading and unloading was not significantly different by season. As implementation, the results in this study recommend that completely removing water the night before slaughter should be avoided.


Comparisons with experimental results are of interest because they provide an indication of the uncertainties of the tabulated stopping powers. We first consider the stopping powers of elemental materials in the energy region where the Bethe theory is applicable. In Figure 5.1, comparisons are made in terms of the ratios of experimental to tabulated stopping powers, for several metals at energies up to 10 MeV (20 MeV for Au). Similar comparisons, in terms of percentage differences, are made in Table 5.1 for 6.5-MeV and 73-MeV protons in metals. The differences between tabulated and experimental stopping powers are mostly smaller than 1 percent and hardly ever greater than 2 percent. Figure 5.2, again for the Bethe energy region, shows similar comparisons for several compounds and mixtures. In this case the uncertainties are approximately three times as large as in the case of elements. In the low-energy region, the dispersion of experimental measurements around the adopted stoppingpower curve can be examined in the data plots of Andersen and Ziegler (1977). Comparisons of this kind have already been shown in Figures 3.2 and 3.3 for gold and amorphous carbo1),. Near the peak of the curve of stopping-power us. energy, around 100-150 keV, the uncertainties of the stopping powers appear to be 20 percent in gold, and 10 percent in carbon. Ratios of experimental to tabulated stopping powers for carbon dioxide, methane, and tissueequivalent gas are shown in Figure 5.3. Down to energies as low as 20 keV, the differences in these cases are 5 percent or smaller; below 20 keV in tissue-equivalent gas they become as large as 25 percent.


Abstract The nitrous oxide (N2O) emission potential of 21 acidic tea field soils in Japan was evaluated using a laboratory incubation method. The range of pH values of the soils was 6.26–2.96, and 17 of the 21 soils were strongly acidified below pH 5.0 due to long-term heavy application of nitrogen fertilizer. The N20 emission potential ranged from 0.001 to 1.463 µg N2O-N g-1 d-1. There was a negative exponential relationship between the soil pH value and N2O emission potential. The application of more than 1,000 kg N ha-1 y-1 of nitrogen fertilizer significantly enhanced the N2O emission potential of acidic tea field soils.


We present a bridge between the KP soliton equations and the Calogero–Moser many-body systems through noncommutative algebraic geometry. The Calogero-Moser systems have a natural geometric interpretation as flows on spaces of spectral curves on a ruled surface. We explain how the meromorphic solutions of the KP hierarchy have an interpretation via a noncommutative ruled surface. Namely, we identify KP Lax operators with vector bundles on quantized cotangent spaces (formulated technically in terms of D-modules). A geometric duality (a variant of the Fourier–Mukai transform) then identifies the parameter space for such vector bundles with that for the spectral curves and sends the KP flows to the Calogero–Moser flows. It follows that the motion and collisions of the poles of the rational, trigonometric and elliptic solutions of the KP hierarchy, as well as of its multicomponent analogs, are governed by the (spin) Calogero–Moser systems on cuspidal, nodal and smooth genus one curves. This provides geometric explanations and generalizations of results of Airault–McKean–Moser, Krichever and Wilson. The present paper is an overview of work to appear in [BN2].


This paper proposes a new artificial neural network-based maximum power point tracker for photovoltaic application. This tracker significantly improves efficiency of the photovoltaic system with series-connection of photovoltaic modules in non-uniform irradiance on photovoltaic array surfaces. The artificial neural network uses irradiance and temperature sensors to generate the maximum power point reference voltage and employ a classical perturb and observe searching algorithm. The structure of the artificial neural network was obtained by numerical modelling using Matlab/Simulink. The artificial neural network was trained using Bayesian regularisation back-propagation algorithms and demonstrated a good prediction of the maximum power point. Efficiency of proposed ANN-based MPP tracker has been estimated for linear shadow expanding and constant partial shading of any one PV module.


In this paper we present Genex+ (Genex plus), an improved implementation of the Genex system (Générateur d'Exemples) [17], by using the semantic closeness between certain fragments of texts. This process was based on the combination of the successive extraction of concordances and collocations with the determination of the semantic closeness by the Mutual Information method [24] and Cosine calculus [3,22]. Results have proven that a good example is almost always associated to the definition of the word to which it is making reference, and that it can be extracted automatically by the consecutive restriction of semantic fields applied to fragments of general language corpora. This has the advantage of presenting a conceptual reformulation of what is said in the definition by using highly informative textual fragments, but with a less formal register. For this second version, we implemented changes required for a bilingual entry.


The Canadian Land Surface Scheme (CLASS), a land-surface parameterisation scheme for use in large-scale climate models, was assessed against the observed surface climates of two alpine tundra sites in western Canada. Half-hourly and daily modelled albedo and net radiation were compared to field observations. Four different simulations using CLASS were employed, each containing different degrees of realism in model configuration. No substantive improvements in model performance were achieved using the more stringent configurations when compared to the model's default specifications. Overall modelling quality for both variables was good. In general, CLASS was conservative when modelling the surface albedo, the diurnal variation in particular. However, the resulting errors in net solar radiation or net radiation were small. In general, CLASS successfully modelled net radiation. Brief summer snowfalls, characteristic of this environment, caused some modelling problems; CLASS did not always recognise when precipitation fell as snow, and demonstrated some difficulty in determining albedo for fresh snow falls, as well as the subsequent decay curve. Copyright © 1999 Royal Meteorological Society


The photochemical reaction of pentane and sulfur dioxide were studied. A series of gaseous products such as alcohols, ketones, esters, sulfuric anhdride, carbon monooxide, carbon dioxide were identified by GC/MS and GC. The reaction kinetics and reaction mechanism were investigated. The influence of initial concentration of reactant on the photochemical reaction of pentane and sulfur dioxide was studied.


Two of the most important commercial molluscan fisheries along the U.S. Atlantic coast are for ocean quahogs Arctica islandica and Atlantic surfclams Spisula solidissima. Both species are common north of Cape Hatteras, North Carolina, their southern boundary. This paper describes how historical and possible future changes in ocean temperature have and could impact these species and their fisheries. Ocean quahogs are typically found in cold water and population genetic data from the mitochondrial cytochrome b gene indicate that the species range shifted in response to environmental warming and cooling since the last ice age, 10,000 years ago. Rising sea temperature in the future would likely cause an offshore and northward contraction of the ocean quahog's range. Atlantic surfclams are not as sensitive to high temperature as ocean quahogs. However, increased sea temperatures off Delaware and Virginia may be stressful because Atlantic surfclam populations in this region already have relatively low growth rates and meat weights associated with high intraspecific density.


Marigold (Calendula officinalis L.) plant growth and orientation were improved by foliar application of gibberellic acid (GA3; 25, 50 and 100 mg L) and -sitosterol (20, 40 and 80 mg L) singly, or in combination. GA3 at 25 mg L more effective increased the number of branches, fresh and dry weight of shoots and roots/plant while GA3 at 100 mg L significantly increased plant height. Leaf angle decreased more with GA3 than with -sitosterol application. Both GA3 (100 mg L) or -sitosterol (40 mg L) significantly induced flowering earliness and number of inflorescences while a low concentration of both substances improved other inflorescence characters. The GA3 (100 mg L) × -sitosterol (40 mg L) interaction significantly increased earliness, number and stalk length of marigold plant inflorescences. Pigments (Chlorophyll (Chl) a and b, and carotenoids) and biochemical constituents (total sugars, indoles and free amino acids) were significantly enhanced by GA3 (25 mg L) and/or -sitosterol (20 or 40 mg L) as a foliar application. However, the highest concentration of both bioregulators resulted in the highest phenolic content of marigold plant leaves. GA3 and -sitosterol were positively correlated to fresh weight of inflorescences and Chl a + b content. There was a significant negative correlation between all results and phenolic content of marigold plant leaves. _____________________________________________________________________________________________________________


Trajectory Specification is the explicit bounding and control of aircraft trajectories such that the position at any point in time is constrained to a precisely defined volume of space. The bounding space is defined by cross-track, along-track, and vertical tolerances relative to a reference trajectory that specifies position as a function of time. The tolerances are dynamic and will be based on the aircraft navigation capabilities and the current traffic situation. Assuming conformance, Trajectory Specification can guarantee safe separation for an arbitrary period of time even in the event of an air traffic control (ATC) system or datalink failure; hence it can help to achieve the high level of safety and reliability needed for ATC automation. It can also reduce the reliance on tactical backup systems during normal operation. This paper applies it to the terminal area around a major airport and presents algorithms and software for detecting and resolving conflicts. A representative set of pairwise conflicts was generated, and a fast-time simulation was run on them. All conflicts were successfully resolved in real time, demonstrating the computational feasibility of the concept.


Knowledge of mathematical transformation models that can present value of vector of geomagnetic field is very important. Defining coefficients of transformation functions provides presentation of disposition value of geomagnetic field on defined space. This article presents geomagnetic field, Gauss' method of analysis of geomagnetic field and using least square method to solve system of equations of normal values geomagnetic field. .


The algorithm process of traditional BP neural network is complex, and a large amount of data is processed in a short time, which easily causes network paralysis, and then affects the accuracy of real-time obstacle avoidance of UAV. Therefore, a real-time obstacle avoidance method based on Improved BP neural network for monocular power line patrol UAV is proposed. On the basis of analyzing the characteristics of the monocular power line inspection UAV, the obstacle avoidance model based on Improved BP neural network is constructed, and then the BP algorithm is used to obtain the real-time obstacle avoidance weight of the UAV, so as to realize the effective obstacle avoidance of the monocular power line inspection UAV. According to the results of this experiment, when the longitude is 125.23°, the latitude is 48.93. And on the premise that the experimental time is 1min, the real-time obstacle avoidance error rate of the monocular power line inspection UAV Based on the improved BP neural network is the lowest, which is only 5.2%.


Interactions with electronic excitations can soften and/or broaden phonons. They are greatly amplified at wavevectors Q+- that connect parallel (nested) sheets of the Fermi surface. In such a case, called a Kohn anomaly, the phonon dispersion sharply dips and its linewidth has a maximum at Q+-. Here we present results of inelastic x-ray scattering measurements that uncovered soft phonons in chromium far from Q+-. They appear in addition to the previously reported soft phonons at Q+-. Calculations in the local density approximation (LDA) show that the new anomalies originate from enhanced electron-phonon coupling. A similar mechanism may explain phonon anomalies away from nesting wavevectors in copper oxide superconductors and other compounds.


Abstract : The U.S. Navy requires all of its aircraft to carry life rafts with capacity equivalent to the personnel capacity of the aircraft. Ejection-seat aircraft are equipped with individual rafts as part of their ejection seat kits. However, other aircraft platforms have the option to carry combinations of four-, seven-, twelve-, or twenty-person rafts, depending upon the capacity of the aircraft and the availability of the different sized rafts. A team from NAWCAD Patuxent River, Maryland, evaluated the current rafts being used to meet this requirement. It concluded substantial improvements in both life cycle costs and performance could be accomplished. This paper describes the new rafts that resulted from the Team's efforts.


Why is there a specific problem with biological individuality? Because the living realm contains a wide range of exotic particular concrete entities that do not easily match our ordinary concept of an individual. Slime moulds, dandelions, siphonophores are among the Odd Entities that excite the ontological zeal of the philosophers of biology. Most of these philosophers, however, seem to believe that these Odd Cases oblige us to refine or revise our common concept of an individual. They think, explicitly or tacitly, that to be a living, evolutionary entity is to be a living individual. In this paper, we explore an alternative proposal: the variety and oddity of the forms of the living realm might be ontologically regimented through an increase in the categorial complexity of the living realm, by admitting, beside living individuals, living non-individuals or by acknowledging, more generally, that the evolutionary development of the living forms is not necessarily a process of building individuals, that life is not necessarily individuals-oriented. We claim that, from an ontological point of view, the spectacle of the living realm obliges us to take aggregativity seriously.

Part of a special issue, Ontologies of Living Beings, guest-edited by A. M. Ferner and Thomas Pradeu


Abstract:While all children are vulnerable in a natural disaster, children who are in foster care because of maltreatment are particularly vulnerable. In the immediate aftermath of a disaster, governments that do not specifically plan for these children may be unable to account for their welfare or location, and foster parents may not have access to government resources. This paper provides a comparative analysis of international law and policy approaches in the United States, Aotearoa New Zealand, and Japan as a means of improving foster children's safety and welfare after a natural disaster. The aim of this article is to draw attention to the gap in comparative scholarly research in the area of disaster planning for children in foster care and to propose possible directions for future research.


Polybrominated diphenyl ethers (PBDEs) have been produced as flame retardants since the early 1970s. They have been found in the aquatic environment since the late 1970s 1,2. Following their discovery in sperm whales from deeper Atlantic waters 3 and in human milk , many laboratories have started to work on PBDE analysis in the environment. A first international interlaboratory study on the analysis of PBDEs was conducted in 1999-2000 5. The results showed that the 18 participating laboratories were able to produce comparable results for BDE 47 in various matrices, but there were significant analytical difficulties for other BDEs, in particular for the BDEs 99 and 209. Meanwhile the presence of other brominated flame retardants (BFRs), such as hexabromocyclododecane (HBCD) and tetrabromobisphenol-A (TBBP-A) and the dimethyl derivative of TBBP-A (MeTBBP-A) in the environment have been reported. Therefore, it appeared to be useful to organize a new interlaboratory study to include these new flame retardants, along with a further study on the PBDEs. This study was conducted between 1 November 2001 and 15 March 2002.


While this experiment is still ongoing, there is a growing consensus that while predictions of
the death of the office are premature, it is likely that there will be a permanent shift towards
increased remote working. Some kind of hybrid arrangement of split working time between
the office and the home (or other 'third space') seems the most likely outcome.


The drawbacks of the traditional simulation tools for DEDS (discrete event dynamic system) were illustrated. A novel method based on COM (component object model) to design DEDS simulation platform was presented. The interfaces based on COM of a generic model of DEDS were illustrated. The principle of the model prototyping can be applied to other DEDS simulation applications. A simulation tool for DEDS was developed via the COM based model prototyping. It provides visual and hierarchical pictures to the construction of a virtual production system. The simulation tool was applied in the simulation of an Iron Steel plant. The simulation results match the real data of the steel making production. The COM based method can be applied to other FMS(flexible manufacturing system) simulations as well.


The material consisted of 250 healthy newborn infants aged a few minutes to 28 days. Ninety of them were premature and 160 were born at term. The distribution of the birth weights is given in Table 1. Several records were usually made from the same infant, using one or several lead systems. Frank's system was the principal method used, and thus a sufficient number of records was obtained to analyse the development of the Vcg finding during the neonatal period. Recordings by the other systems were confined to a few age groups and the results were compared with those obtained by Frank's method. A total of 360 recordings were made by Frank's method. Their distribution into age groups is given in Table 2, which also shows the number of


The synergistic effect of two interfacial junctions of a p–m–n composite was indicated to enable energy-dependent charge-flow steering for photocatalysis.


Managers in making decisions usually require a large number of statistics and statements. The convenience attain required documents in time would be a major challenge in management. This paper would apply Web2App/Pa technology in the App program design and development of the secure transmission of documents and information statements through enterprise management system. Through the encryption/decryption process, so that managers could get the most immediate information to facilitate the decision-making to enhance the management effectiveness and efficiency by the integration of wireless communication technology and cloud resources through smart phones


We characterize the membership of Hankel operators with general symbols in the Schatten Classes $S^p,\, p\in(0,1),$ of the large Bergman spaces $A^2_{\omega}$. The case $p\geq 1$ was proved by Lin and Rochberg.


In this article, we review the factors that contribute to obesity. We then describe effective approaches to weight control, including exercise, dietary modification, drug treatment, and bariatric surgery.


Statins generally are contraindicated during pregnancy because of animal-study data and other theoretical concerns about teratogenic potential. In this study, U.S. investigators used Medicaid data (2000–2007) to assess risk for congenital malformations with maternal statin use in nearly 890,000 pregnancies linked to live-born infants.

A total …


The effect of heliotherapy on psoriasis skin lesions and arthritis was studied in a trial comprising 4 weeks of therapy in the Canary Islands and a 6‐nionth follow‐up period, A total of 373 patients participated in the heliotherapy and in patients completed the follow‐up period. The severity of skin lesions was evaluated using a psoriasis severity index (PSI), and that of the arthropathy by using an arthritis index (AI).


Preexisting adenovirus immunity in humans limits the use of adenoviruses vectors for gene therapy and vaccines. Therefore, in this thesis, a newer class of adenovirus (Ad) vectors belonging to the poorly understood species G of adenoviruses, rhesus adenoviruses (RhAds), are investigated for their viability as vaccine vectors and for their ability to evade preexisting human adenovirus (HuAd) immunity. Moreover, we investigate the extent of cross-reactive adenovirus immunity. RhAd vectors exhibited potent humoral and cellular immunogenicity as both priming and boosting vectors and induced favorable immunological phenotypes with high anamnestic capacity. Moreover, RhAds vectors were not hindered by preexisting human adenovirus immunity in the mouse model. In humans, we detected extensive CD4+, but limited CD8+ T cell crossreactivity between RhAd and HuAd vectors, and cross-reactive CD8+ T cells were largely driven by single immunodominant epitopes in conserved regions. Minimal to no crossreactive neutralizing antibodies were detected. These data suggest the potential utility of RhAd vectors for vaccines or gene therapy and define cross-reactive T cell epitopes between phylogenetically distinct adenoviruses that may be useful in future vector


Wave-domain adaptive filtering for echo cancellation has been proposed for achieving immersive full-duplex sound conferencing that uses wave field reconstruction as spatial sound rendering. In wave-domain adaptive filtering, fundamental solutions of the wave equation are spatially sampled and used as the orthogonal basis functions. This sampling is determined by loudspeaker spacing and results in aliasing; aliasing occurs above a few thousand Hz for spacing of several centimeters. The goal of this work is to investigate the effect of applying adaptive filtering on echo signal with aliasing when the loudspeaker array and microphone array are uniform linear arrays of identical geometries. We came to the conclusion that we can apply the wave-domain echo-path model, used below spatial Nyquist frequency, to wave-domain adaptive filtering over this frequency even in the presence of aliasing components.


CD9 is a four transmembrane protein belonging to a tetraspanin family and regulates cell motility and adhesion. Several reports have indicated that CD9 form complexes with integrin including platelet fibrinogen receptor integrin aIIb-b III and involve in platelet function. We have previously reported that the c-myb knock down (KD) mice exhibited anemia and thrombocytopenia, and the expression level of CD9 mRNA was markdly increased in the c-myb KD mice. Reverse correlation of c-Myb expression with the CD9 gene expression was verified and agonistic antibody of CD9 stimulated megakaryocytic colony formation. These observations suggested that the CD9 expression was downregulated by c-myb . In our current study, we investigated the role of CD9 during megakaryopoiesis and platelet function by using CD9-null mice. Numbers of megakaryocytes and platelets, CFU-Meg, and ploidy were not different between wild-type and CD9-null mice. However, proplatelet formation (PPF) was significantly impaired in CD9-null megakaryocytes, and the size of proplatelets was smaller than those generated by wild-type megakaryocytes. Furthermore, after the bone marrow suppression with 5-fluorouracil (5-Fu), the recovery phase of platelet counts were delayed in the CD9-null mice. To clarify the reason of this platelet- recover delay, the number of bone marrow megakaryocyte was investigated using anti-vWF antibody staining, but the serial measurement of megakaryocyte number in CD9-null mice was not changed compared with wild-type mice. And also megakaryocyte ploidy was not changed in CD9-null mice compared with wild-type mice. Previous reports revealed that the cytoskeleton reorganization has a key role for the PPF formation, and Rac1-PAK1 signaling is important for actin restructure and aggregation prior to the cytoskeleton reorganization. The PPF formation was suppressed by Rac1 inhibitor. Although the mRNA expression levels of Rac1 in CD9-null mice were almost same as that in wild-type mice, PAK1 activation, major target of Rac1, was delayed in CD9-null mice compared with wild-type mice using thrombin-stimulating platelets. These results suggested that the delay of PAK1 activation cause the suppression of PPF formation in CD9-null mice. Our previous and current studies demonstrate that c-Myb suppresses the CD9 expression in a steady-state condition, while in the stress megakaryocytosis, CD9 is upregulated and acts to induce megakaryopoiesis and platelets production through Rac1-PAK1 signaling pathway. Elucidation of c-Myb-CD9 regulatory function seems to be important to understand the stress megakaryopoiesis.


Machine learning algorithms have been widely used for classification purposes in a number of research domains; however, very few researches paid any attention to statistically validate the performance of these algorithms for different data. This paper attempted to study the Naïve Bayes algorithm's performance for dataset of different sizes. Furthermore, a known theory has also been investigated, that building multiple models such as Bagging, Boosting and Stacking tend to improve a classifier's performance. The analysis has been performed using McNemar's test; a well known nonparametric statistical test in the medical analysis domain. Results showed that not all ensemble methods work as expected and therefore, needs to be selected carefully. Moreover, the use of McNemar's test appeared to be simple, but gave statistically valid results.


The subject of the present study is the depiction of the existing situation and the available methods concerning the management and the exploitation of the οlive oil mills wastes. There is a review of the basic environmental aspects and the effects of the oil production processes, as well as of the following processing of the by- products which result from them, from a pomace oil extraction plant unit with the approach of some of the basic requirements which compose of an Environmental Management System. The aim of the presented study, is the investigation of the waste process efficiency from the pomace oil extraction plant unit in correlation with the frames defined by Systems of Environmental Management.
The increase of oil production in recent years has as result the parallel increase of the οlive oil mills wastes. The management of the pre- referred wastes, especially of the olive mills wastewater (OMWW), constitutes one of the most important problems of the oil sector, taking into account the disproportionate amount in the available time required for their rational and efficient confrontation. The 2- phase procedure system of the olive compared to the 3-phase one has the advantage that it does not produce OMWW. Instead, it produces increased in moisture olive pomace cake as waste, which consequently requires a special processing compared to the 3- phase one.
During the study of the case there was a comparison between the procedure systems of 2- phase and 3- phase olive pomace cake in the pomace oil extraction plant in relation to the environmental aspects resulting from the required processes. According to their importance, the categories of the liquid wastes, the emissions and the energy consumption, were mainly studied. Conclusively, the repression of OMWW by the 2- phase system is offset by the increased energy consumption and consequently the increased production of emission. The confrontation of the above environmental aspects sets an issue of vital importance not only for the environment but also for the viability of the pomace oil extractions plants, since they depend directly on the energy consumption.
The principles of the Environmental Management Systems can constitute a defining and oriented system for the given activities and the constant improvement of the environmental footprint and besides for the creation of economic development circumstances.


Abstract : For many people, the term urban operations brings to mind the specters of Mogadishu, Hue City, and Stalingrad, where vicious, house-to-house infantry fighting was the order of the day. However, it is a mistake to view all urban operations through this bloody lens. Such operations fall all along the spectrum of military operations -- from humanitarian relief to peace support to major theater war. Aerospace power can play a major role in helping the joint force achieve its objectives with less risk in many scenarios across this operational continuum. From a historical perspective, urban operations are not a new phenomenon for the Air Force or our sister services. Joint aerospace power in various forms has contributed significantly to successfully executed urban operations in many recent conflicts and contingencies. Most urban operations will include five components. Arguably the most important component of our concept of operations, battle-space analysis encompasses preparing intelligence concerning the battle space and maintaining operational-level situational awareness during all phases of the campaign. The second component in a joint urban operation, isolation involves physically and psychologically separating an adversary from his urban support base, limiting his mobility and communication, and negating his ability to acquire useful intelligence on friendly operations. The decisive-engagement component involves gaining the initiative by applying friendly strengths against the key nodes, systems, and choke points identified during the JFC's battle-space analysis. The third component is sustainment. Prerequisites for its success are continuous, real-time analysis of the battle space; operational effects achieved against key nodes and systems; and adversary responses. The final component of our operational concept refers to a variety of long-term, peace-shaping operations that ultimately mark the termination of urban violence or armed conflict.


Cancer is one of the leading causes of death worldwide. Fast and safe early-stage, pre- and intraoperative diagnostics can significantly contribute to successful cancer identification and treatment. Artificial intelligence has played an increasing role in the enhancement of cancer diagnostics techniques in the last 15 years. This review covers the advances of artificial intelligence applications in well-established techniques such as MRI and CT. Also, it shows its high potential in combination with optical spectroscopy-based approaches that are under development for mobile, ultra-fast, and low-invasive diagnostics. I will show how spectroscopy-based approaches can reduce the time of tissue preparation for pathological analysis by making thin-slicing or haematoxylin-and-eosin staining obsolete. I will present examples of spectroscopic tools for fast and low-invasive ex- and in-vivo tissue classification for the determination of a tumour and its boundaries. Also, I will discuss that, contrary to MRI and CT, spectroscopic measurements do not require the administration of chemical agents to enhance the quality of cancer imaging which contributes to the development of more secure diagnostic methods. Overall, we will see that the combination of spectroscopy and artificial intelligence constitutes a highly promising and fast-developing field of medical technology that will soon augment available cancer diagnostic methods. data analysis to the development of fast and low- or non-invasive methods. This shows how AI methods have proven their effectiveness in the of data generated by conventional diagnostic methods in oncology such as the histopathological study of biopsy samples, and laboratory studies of we reviewed promising spectroscopy-based methods for tissue imaging and analysis that might enhance the toolbox of effective and precise diagnostic


The results of the study of the relationship of cadmium quantitative content in biologic media with generalized periodontitis are presented in the paper. Generalized periodontitis is known to be of one of cadmium toxic effects manifestations.


ABSTRACT What did peasants discuss at party meetings? Were they mobilized by ethnic politics or indifferent to them altogether? The end of the First World War brought about universal male suffrage in much of Europe, and with it the process of mass politics began. The concept of national indifference is important in understanding interwar politics, because this period is often studied teleologically with attention focused on extremism and nationalism as the primary mobilizing issue Agrarian movements have been under-researched, and when Agrarians have been studied, it has been through the prism of elite politics. This comparative paper seeks to redress this omission by looking at grassroots rural politics. The interwar countryside was marked by profound political, economic and social transformation but also in terms of what Robert Paxton has described as the 'triple crisis of the countryside' – worsening economic conditions, the declining status of the countryside and inadequate political representation. The paper will explore how reform and crisis impacted how agrarian politics functioned at a local level by asymmetrically comparing cases from Romania, Poland and Ireland, with the final case helping to contextualize Eastern Europe within the wider European experience This paper argues that the rural population was mobilized, but primarily in the context of local issues rather than national ethno-political questions. Local party organization was, to paraphrase James C Scott, the site 'of an exchange of small arms fire' in rural class conflict, as questions regarding the control of public space, generational conflict and power within the village mobilized peasants. Thus, I argue that it was the underlying socio-economic issues that mobilized the rural population, not nationalism. The dynamics of these conflicts were shaped by local economic, political and social power dynamics, and by using indifference as a concept, we can look more deeply at interwar politics from a grassroots perspective and develop a more nuanced understanding of local, national and European politics.


This action research study was focused on the improvement of the pronunciation skill with the use of songs of 29 fourth-B year students at "Zoila Alvarado de Jaramillo" public school. Eight sessions were carried out to improve the skill using English children songs. Researcher's-made tests and questionnaires were used to measure the students' progress and perception of the songs use and the pronunciation. Field diaries were also used in every session to observe and record the students' growth. The results indicated that the use of songs facilitated meaningfully the improvement of pronunciation skill which was reflected in the noticeable increase of the posttest scores and students' progress during the intervention.


In this Chapter we shall consider a generalization of Hermite-Biehler Theorem1 given by Pontryagin in the paper Pontryagin (1955). It should be understood that Pontryagin's generalization is a very relevant formal tool for the mathematical analysis of stability of quasipolynomials. Thus, from this point of view, the determination of the zeros of a quasipolynomial by means of Pontryagin's Theorem can be considered to be a mathematical method for analysis of stabilization of a class of linear time invariant systems with time delay. Section 2 contains an overview of the representation of entire functions as an infinite product by way of Weierstrass' Theorem—as well as Hadamard's Theorem. Section 3 is devoted to an exposition to the Theory of Quasipolynomials via Pontryagin's Theorem in addition to a generalization of Hermite-Biehler Theorem. Section 4 deals with applications of Pontryagin's Theorem to analysis of stabilization for a class of linear time invariant systems with time delays.