Problem statement: Considering the importance of emergency departments in healthcare system and the high mortality rate of patients refe rred to these departments, it is crucial to provide quality services in emergency departments. Accredit ation is a systematic process for improving quality of care and it enables managers to assess and evalu ate the healthcare system. Accreditation of an organization provides an obvious commitment for improving quality of safety, quality of patient care, ensuring safety surveillance and continuous activit ies for reducing dangers which threaten patients an d staff. Therefore, given the vital role as well as a nd the perpetual and indispensable service provided by the emergency departments, it is necessary to re-ev aluate the manner of service provision in these departments according to the standards and criteria of accreditation, so that an observance of these criteria will lead to improvement of emergency medi cine in Iran. Thus, the present study was undertaken with the purpose of accreditation of eme rgency department of a teaching hospital of Tehran University of Medical Sciences according to the sta ndards of Iranian Deputy of Health and the JCI. Approach: This is a descriptive-analytic study with a cross- sectional structure. Our study population consisted of 50 individuals of the healthcare staff (physicians and nurses) working in morning and evening work shifts of the emergency department in the teac hing hospital. Data collection tools consisted of s tandard questionnaires of the Deputy of Health (9 series) a nd questionnaires developed by authors based on the standards of the Joint Commission International (JC I) regarding patient satisfaction with services pro vided in emergency departments. In order to determine the reliability and validity of the data collection to ols, professors and experts reviewed the questionnaire o f quality and patient safety in accordance with sta ndards of quality patient safety from the standards of pat ient satisfaction prepared by the JCI. Subsequently , the questionnaires were used in the emergency department of a teaching Hospital with approval of the head of department. Moreover, they said questionnaire was critiqued for its content and then reviewed conceptu ally. The reliability of the questionnaire was confirmed with a Cronbach's α of 95%. Results: According to the relevant standards and the checklists provided by t he Deputy of Health for influencing factors (such a s human resources, ethical issues and observance of r eligious measures, structural issues, medical equip ment and medications, provision of other medical service s, nonmedical equipment), our evaluation of the emergency department in teaching Hospital yielded a score of 1626 points (86.81% of the maximum score) for the department. Conclusion: The above findings the emergency department in thi s hospital requires certain plans for improving the status quo. Therefo re, the current deficiencies must be addressed with a comprehensive plan so that accreditation by the JCI may become feasible.


The invention discloses a fixed-asset management system based on the RFID technology. The system comprises electronic tags, a reader, a primary server, a data query terminal and a total server. The contents of the identified electronic tags are transmitted to the reader. After the electronic tags are decoded by the reader, information is transmitted to the primary server. The server conducts corresponding processing after the comparison of signals. According to the fixed-asset management system, online real-time monitoring can be achieved, whether the movement of fixed assets is legal or not can be judged, the operating speed of the system is high, and the data loss rate is low.


The reported paleomagnetic study was carried out on 53 oriented samples (156 specimens) at 10 sites in the eastern Gaspe Peninsula. All sampled geological units are composed of sub vertical diabase dykes that cut the sedimentary formations of late Early Devonian – early Middle Devonian age. The radiogenic (whole-rock K/Ar) age of these and similar dykes ranges from Late Devonian to early Middle Carboniferous (mean whole rock K/Ar age = 310 Ma). Two components were isolated. The most common component, A (D = 152°, I = +41°), is normal, whereas the second component, B (D = 315°, I = −44°), is reverse. Both components may be considered as a single one; alternatively, component A may be considered slightly older than component B. Unblocking temperatures, median destructive fields, relative frequency of occurrence of the components, and various degrees of alteration are arguments favouring the first or the second situation. The case of a single component is more probable, representing an Early Carboniferous ti...


BACKGROUND/AIMS
There is a major unmet need to assess the prognostic impact of anti-fibrotics in clinical trials due to the slow rate of liver fibrosis progression. We aimed to develop a surrogate biomarker to predict future fibrosis progression.

METHODS
A Fibrosis Progression Signature (FPS) was defined to predict fibrosis progression within 5 years in HCV and NAFLD patients with no to minimal fibrosis at baseline (n=421), and validated in an independent NAFLD cohort (n=78). The FPS was used to assess response to 13 candidate anti-fibrotics in organotypic ex vivo cultures of clinical fibrotic liver tissues (n=78), and cenicriviroc in NASH patients enrolled in a clinical trial (n=19, NCT02217475). A serum-protein-based surrogate FPS (FPSec) was developed and tested in a cohort of compensated cirrhosis patients (n=122).

RESULTS
A 20-gene FPS was defined and validated in an independent NAFLD cohort (aOR=10.93, AUROC=0.86). Among computationally inferred fibrosis-driving FPS genes, BCL2 was confirmed as a potential pharmacological target using clinical liver tissues. Systematic ex vivo evaluation of 13 candidate anti-fibrotics identified rational combination therapies based on epigallocatechin gallate, which were validated for enhanced anti-fibrotic effect in ex vivo culture of clinical liver tissues. In NASH patients treated with cenicriviroc, FPS modulation was associated with 1-year fibrosis improvement accompanied by suppression of the E2F pathway. Induction of PPARα pathway was absent in patients without fibrosis improvement, suggesting benefit of combining PPARα agonism to improve anti-fibrotic efficacy of cenicriviroc. A 7-protein FPSec was associated with development of decompensation in cirrhosis patients.

CONCLUSION
FPS predicts long-term fibrosis progression in an etiology-agnostic manner, which can inform anti-fibrotic drug development.


The article analyzes the changes of the informative and organizational character which have occurred in the system of preschool education at the turn of the century. Problems of quality, preschool education standardization, continuity of preschool and primary general education are covered.


A high-quality dynamic far infrared image is produced by projecting a high-quality visible image onto a unique transducer. The transducer consists of a very thin insulating film (approximately 500 A) with a thin coating of a good visible light absorber-far infrared emitter such as some metallic blacks.


Complement is an important effector pathway of innate stranded DNA antibodies was low, positive in only five immunity. In this review the role of complement in the of the 24 patients tested. pathogenesis of systemic lupus erythematosus (SLE) is Hereditary deficiency of C1s and C1r is rarer than described. There are important associations between that of C1q deficiency and, in the majority of cases, both inherited and acquired complement component deficiencies of both components coincide [3–5]. In such deficiencies and SLE. These have focused attention on cases C1r levels are usually absent with levels of C1s identifying the relevant physiological role of the classical below 50% of normal. As in homozygous C1q deficiency, pathway of complement activation that appears to proSLE occurs in the majority of these individuals (seven tect against the development of SLE. There is also of the 11 reported cases). Selective C1s deficiency, i.e. unequivocal evidence that major histocompatibility with normal C1r levels, has been reported in association complex (MHC) genes play an important role in deterwith SLE [6 ]. In homozygous C4 deficiency, the prevalmining both disease susceptibility and phenotype in SLE ence of SLE is approximately 75% and the lupus illness and its subsets. Accordingly, the role of complement is of moderate severity [7]. genes located in the class III region (C4A, C4B and C2) Homozygous C2 deficiency is the commonest inherited in the genetic susceptibility to SLE is reviewed. The classical pathway complement deficiency with an utility of the measurement of complement levels in approximate prevalence in Western European Caucasoid monitoring disease activity and the clinical significance populations of 1:20 000. In contrast to homozygous C1q of hypocomplementaemia are discussed. Homozygous deficiency, the majority of affected individuals are probC1q deficiency is the strongest genetic susceptibility ably healthy. SLE may occur in up to 33%, although factor for SLE that has been identified in humans, but, this figure may be an overestimate due to ascertainment paradoxically, SLE causes C1q consumption and is artefact, and the severity of the illness is comparable to commonly associated with anti-C1q antibodies. The role that seen in SLE patients without homozygous compleof complement in the pathogenesis of lupus, with parment deficiency. In contrast to the classical pathway ticular emphasis on the role of C1q, is discussed in order components, homozygous C3 deficiency predisposes to to explain this paradox. recurrent pyogenic infections and membranoproliferative glomerulonephritis (MPGN), but SLE is rare [8]. What do the clinical observations in individuals with Homozygous classical pathway component homozygous classical pathway component deficiency deficiency and SLE teach us about the pathogenesis of SLE? They suggest that there is a physiological function of the classical Homozygous hereditary deficiency of each of the claspathway of complement activation that protects against sical pathway components (C1q, C1r, C1s, C4, and C2) the development of SLE. Furthermore, the hierarchy of is associated with an increased susceptibility to SLE [1]. susceptibility and the severity of lupus, according to the Both the severity of disease and the strength of this missing classical pathway protein (C1q>C4>>C2), association is greatest for homozygous C1q deficiency suggest that the early part of the classical pathway plays followed in turn by homozygous C4 and C2 deficiency. a key protective role against the disease. Since one of Thirty-eight of the 41 patients with homozygous C1q the major roles of the classical pathway is that of host deficiency reported to date have developed a clinical defence against infectious disease, one hypothesis is that syndrome closely similar to SLE (recently reviewed in classical pathway component deficiency predisposes to [2]). In the affected patients rash occurred in 36, glomSLE because of impaired resistance to an infectious erulonephritis in 16, and cerebral disease in seven. trigger. Antinuclear antibodies (ANA) were reported in 24 and There is little evidence in favour of this hypothesis. antibodies to extractable nuclear antigens in 15 of these Classical pathway complement deficiencies are not assopatients, but notably, the incidence of anti-doubleciated with an overt increase in susceptibility to viral or fungal infections. Although complement deficiency is Submitted 9 July 1999; revised version accepted 15 July 1999. Correspondence to: M. J. Walport. strongly associated with the development of pyogenic


Iodide of potassium, the Iodkalium of the Germans, and the iodure de potassium of the French, is made by the addition oF iodine in excess to an aqueous solution of potassa. It occurs in semi-opaque, white, transparent or colorless crystals, permanent in a dry air, rather deliquescent in a moist one, of an acrid saline taste. It is soluble in two-thirds its weight of water, and in six to eight parts of alcohol.


Objective To understand the incidence of influenza in Xicheng district in Beijing and provide evidence for influenza prevention and control.Methods The throat swabs were collected from the influenza like illness(ILI) patients in two sentinel hospitals in Xicheng district to conduct RT-PCR for influenza virus nucleic acid detection,and MDCK cell was used for the isolation of virus.Results A total of 17 549 ILI cases were reported from October 2010 to April 2011,accounting for 2.24% of all outpatients(17 549/784 625).Among 905 throat swabs collected,297 were positive in influenza virus nucleic acid detection(32.82%).Seventy influenza virus strains were isolated(23.57%),including 35 strains of A(H1N1) pdm 09 virus,25 strains of seasonal A(H3) virus,7 strains of B virus/Victoria lineage and 3 strain of A virus unspecified.Conclusion The incidence of influenza peaked during December-January in Xicheng district during 2010-2011,A(H1N1) pdm 09 virus,seasonal A(H3) virus and B virus co-circulated.


This study aims to explore the impact of enterprise resource planning (ERP) implementation on management accounting practices (MAPs), and main attributes that influence the ERP implementation in Jordanian manufacturing companies. A questionnaire survey was distributed to Jordanian manufacturing companies. This study shows that ERP has connected and integrated a wide range of companies functions and resources, which offers them a new platform of information on how to manage their operations holistically. This can explain the considerable variation in the extent of MAPs' adoption among the Jordanian companies, and enterprise systems have the potential to facilitate both conventional and advanced MAPs. Dealing with changes in business operations, the best practice recommendations, and recommendations from different professional bodies were found as main institutional attributes leading to the use of ERP. Lack of sufficient support and lack of top management support were the two main other factors that may prevent ERP implementation in the Jordanian context.


This paper presents a numerical approach to study the fluid-thermal-structure coupling problems of laminated film cooling configurations. The SST k-ω turbulence model, T-grid technology, and SIMPLEC algorithm in the commercial tool Fluent 6.3 were employed to solve the coupling problems of flowing fluid and heat transfer within the solid configurations. The numerical method and program were validated with the experimental date obtained by an infrared thermal imaging system in the first part of this work. The validated method and program were applied to analyze the coupling effects of variant solid structure devices, and the influences of film-hole angles and rib-arrangements on cooling effectiveness were compared. The temperature fields obtained by the validated program were input into another commercial tool, Ansys 11, to estimate the thermal stress profiles within the configurations. The fluid-thermal-structure characteristics of the laminated cooling configurations were synthetically discussed.Copyright © 2009 by ASME


In recent years, Chile's vehicle fleet has undergone great changes, with 25% growth in motor vehicles. This increase is directly related to improvements in the performance of flexible pavements, which make infrastructure less susceptible to permanent deformations and/or cracking at high and low temperatures, respectively. In 2016, the Ministry of the Environment passed the Law on Recycling and Accountability to promote the search for innovative ideas and materials in different sectors. This research focused on the experimental study of the mechanical behaviour of a mixture of hot asphalt, incorporating thick particles of polyethylene terephthalate (PET) from bottle recycling, using the Marshall stability and flow test and the resilience module (rigidity) test at 5°C and 22°C. Based on previous research, significant PET fibre sizes were used, increasing the optimum amount of polyethylene terephthalate from 6% to 14% in the mixture. The results show that incorporating this polymeric additive provides greater stability, in addition to an increase in resistance to permanent deformations and fatigue, compared to a "traditional" mixture.


The numerical solution of second kind Fredholm integral equations by the discrete collocation method and a discrete iterated collocation method is studied. Orders of convergence for the two discrete methods are given for the case in which an interpolatory quadrature rule of appropriate precision is used. If the kernel is sufficiently smooth, these orders of convergence will be the same as those of the exact methods. Some numerical results are given.


We review variable valve actuation (VVA) concepts and also present the results of our work in the creative synthesis of these devices. We begin with a comprehensive survey of existing VVA devices. We then describe our work on four VVA concepts which we have explored in considerable detail. These include hydraulic lost-motion variable-lift systems, in both the direct acting and the roller-finger-follower configurations, several valve deactivation mechanisms with unique features, a variable valve-lift mechanism, and a variable-lift and duration concept. These devices differ in their complexity and versatility but offer a spectrum of design solutions applicable to a range of products. The strengths and weaknesses of these different approaches are discussed and analyzed, and some test results are presented.Copyright © 2008 by ASME


Hue city was chosen for a pilot application of indicators on environmentally sustainable city, which were developed by Vietnam Ministry of Natural Resources and Environment. The indicator set is composed of four key categories (water, air, solid waste and climate change response), which are broken down into 16 underlying performance indicators. In reality, there has not been any assessment process in place to guide cities in Vietnam in doing their own assessment. In this research, an assessment process including 5 steps was built up; and a barometer with 5 classification bands ranging from 0 to 100 was recommended to use for both category and overall assessment. The weighting of 4 urban environmental categories was undertaken based upon a Delphi method with informed inputs from an expert panel. The 5 - step analysis process showed that Hue city was ranked "medium" with the score between 41 - 60 for water and solid waste, "fairly good" in terms of air (score of 85) and "poor" as to climate change response (score of 40). The sum of all category scores of Hue city, which is also rebased to 100, is valued at 60. Thus, the city was ranked "fairly good" in the overall. Such assessment results are much expected to provide assistance in decision-making at various levels of local authority and help them set forth some appropriate improvement measures on urban environmental sustainability issues. As such, the city would soon meet some concerned requirements to become a leading city of Vietnam in urban environmental sustainability.


In their eagerness to capitalize on the tremendous opportunities there, American businesses are venturing into the Soviet Union with little or no knowledge of Soviet culture or negotiation processes and style. In addition to encouraging unrealistic expectations, this lack of awareness not only increases the frustrations of negotiating with officials from a non-market economy such as the Soviet Union, but also severely impedes decisions about doing business there. It is imperative that U.S. business executives understand Soviet commercial negotiation processes and style if they are to be successful in garnering the huge potential of the Soviet market.


Are consumers tired of standing out? This study probes whether or not fast fashion understands the implicit behavior of their customers while dressing up or down. Retailers tend to market their more ready-to-wear (dress-down) fashion product in an approach that allows the customer to customize the outfits to become easily "me-self," through a big selection of accessories for men and women such as hats, glasses, and scarves. Versus the dress-up look that echoes with conforming to social norms. Today marketers seem to misunderstand the tendency that when one dresses down they often seek to blend in more with the environment rather than display their own personality through fashion. The study extends the literature through explicating the process of picture introspection and member check using confirmatory personal introspection (CPI). Even though when one dresses down you would expect more individuality, according to the findings the subject sample was also more inclined to blend in society and stand out less. In the dress-up look there was a strong call for displaying features of a powerful and strong individuality.


This study examined how the Foreign Direct Investment inflows in Ethiopia is determined by, the financial sector development, domestic investment, lending interest rate, exchange rate, human capital development ,trade openness and domestic market potential in Ethiopia. In doing so, the study used a VECM with co-integration based on secondary data from 1975-2014 collected from various sources. The study revealed that, FDI in Ethiopia is highly determined by domestic investment, lending interest rate, exchange rate depreciation, domestic market potential and trade openness. However, human capital development and financial sector development are found to be an insignificant effect on FDI in Ethiopia. So that, the government of Ethiopia needs to work towards increasing the countries market potential by further enhancing the economic growth. Besides, it needs to continue the existing managed floating exchange rate regime, modifying the existing lending interest rate based on the kind of investment and kind of benefit the government and the country will have got, work towards encouraging the import substituting foreign direct investment. Keywords: Vector Error Correction Model, FDI, Depreciation, Co-integration


The article is devoted to the international relations between Russia and the Holy Roman Empire in the end of the XVI beginning of the XVII centuries. Special attention is given to the following directions: first, the attempts to establish dynastic relations between the Godunovs and the Gabsburgs; second, relations in the sphere of military and political cooperation; third, relations in the cultural sphere.


This paper represents a theoretical study of the transmission and the electronic band structure for a GaAs/GaAlAs Multi-quantum wells, containing two defect layers: a geo-material and a material defect layer. The variation of the different physical parameters ( i.e the transmission rate and the energy of the eigen states) as a function of the defect layers nature, is carefully investigated using the Green's function method. Due to the presence of the defect layers, localized electronic states appeared and their properties have been studied. Our results show that both the position and the thickness of the defect layers can play an important role in the creation of well-defined localized electronic states inside the band gaps, in order to favor the transfer of electrons, without using a higher energy. Furthermore, we were able to identify the origin of each of the states appearing inside the band gaps, whether they are induced by the geo-material or by the material defect.


In this communication, the pathos edge semi-middle graph of a tree is introduced. Its study is concentrated only on trees. We present a characterization of those graphs whose pathos edge semi-middle graph of a tree is planar, outerplanar and minimally nonouterplanar. Further, Also we establish a characterization of graphs whose pathos edge semi-middle graph of a trees are noneularian, hamiltonian and the graphs whose crossing number one and two.


This note presents a uniform treatment of normality and three of its variants---topological, weak and seminormality---for Noetherian schemes. The key is to define these notions for pairs $(Z, X)$ consisting of a (not necessarily reduced) scheme $X$ and a closed, nowhere dense subscheme $Z$. An advantage of the new definitions is that, unlike the usual absolute ones, they are preserved by completions. This shortens some of the proofs and leads to more general results. Version 2: small changes.


The purpose of this study was to analyze the effect of digital marketing and product quality on customer loyalty. This research is a quantitative research with a descriptive and verification approach. From the research that has been done, it is obtained that the value of t count > t table so that digital marketing and product quality have a positive and significant effect on customer loyalty. The R-square value obtained is 0.852 which states that digital marketing and product quality variables affect customer loyalty by 85.20% and the remaining 14.80% is influenced by other variables.


Peristenus spretus Chen et van Achterberg (Hymenoptera: Braconidae), a parasitoid of the plant bug Apolygus lucorum (Hemiptera: Miridae), has been studied for use in augmentative biological control in China. Under laboratory conditions, we explored the development, survival, age-specific and potential lifetime fecundity, oviposition period and progeny sex ratio of P. spretus reared at six constant temperatures (15°C, 19°C, 23°C, 27°C, 31°C, 35°C) on the second instar nymphs of A. lucorum. At 15°C, male and female P. spretus took 48.7 ± 0.3 and 52.5 ± 0.3 days to complete their immature development, while developmental time was reduced by more than half at 23°C and 27°C. The parasitoid can only develop to the larval stage at 31°C and neither larva nor pupa survived at 35°C. The estimated lower developmental threshold of the immature stage was 7.3°C. When parasitoid adults were exposed at 15°C, females laid 90% of their eggs at first 19 days of oviposition and had an extended reproductive life. In contrast, females held at 27°C laid most of their eggs (90%) in their first of 10 days of oviposition and had shorter longevity. The highest potential lifetime fecundity of P. spretus was 671.2 ± 34.7 SE eggs produced over 23.4 ± 1.4 SE days at 23°C. At 15°C, 19°C and 23°C, sex ratios of reared parasitoids were male-biased, but at 27°C there was no male bias.


As a substantial and unique employer of bands and orchestras, the World's Columbian Exposition in Chicago both enhanced the American musical scene of the 1890s and dramatized its complexities and divisions. At issue throughout the duration of the fair was the clash between advocates of the so-designated artistic programs presented by the Exposition Orchestra and proponents of the popular programs given by concert bands.


Abstract : The objective of the study is to validate pupillary light reflex (PLR), saccadic and convergence eye movements as objective biomarkers for the identification of Warfighters with acute mild traumatic brain injury (mTBI) using commercial-off-the-shelf (COTS) instruments: infrared pupillometers, King-Devick (KD) test and near point of convergence (NPC) rule, respectively. Hundred mTBI and 100 age-matched non-TBI (controls) military personnel are to be recruited from the patient population at Womack Army Medical Center (WAMC). This study was designed determine within each group the effectiveness of these tests, individually and/or in combination, to correctly identify mTBI in agreement with the mTBI diagnosis made by the WAMC Department of Brain Injury Medicine. Preliminary results showed that three of the eight PLR parameters are statistically different between the groups: average constriction velocity, average dilation velocity, and 75% dilation recovery time. In addition, the KD test, NPC rule, and the CISS survey showed sensitivity in identifying military personnel with mTBI.


We study high-energy elastic and inelastic processes in a ${\ensuremath{\phi}}^{3}$ theory based on the following model: For the elastic-scattering amplitude we first sum the leading terms in each order of perturbation of the $t$-channel straight ladders, plus those obtained by interchange of the Mandelstam variables $s$ and $u$. We then perform the $s$-channel iteration with the $t$-channel ladders as single units. We are only interested in the physical regions in which the incident particles retain their large momenta. This procedure leads to the eikonalization of the $t$-channel ladders. For the inelastic production amplitude, the dominant contribution comes from diagrams with any number of totally open ladders (i.e., multiperipheral chains) modified by unopen ones. The main results are: (a) The total cross section approaches zero, approaches a constant, or increases as ${(\mathrm{lns})}^{2}$ according as the coupling constant is smaller than, equal to, or larger than a critical value. (b) Elastic and inelastic differential cross sections are computed, and they have many nice features, as suggested by the absorption model. (c) Nonforward $s$-channel unitarity is explicitly verified. (d) One-particle and multiparticle spectra, the average multiplicity, the number distribution of the final particles, etc., are obtained. The implications of these results to hadron physics are discussed.


Objective To study the clinical significance of PTFV1 changes in essential hypertension with normal left ventricular ejection fraction(LVEF).Methods A total of 232 essential hypertension patients with normal LVEF were divided into 2 groups according to PTFV1- 0.03mms as criteria.156 patients with PTFV1- 0.03mm.s were observation group and another 76 patients with PTFV1≥- 0.03mm.s were control group.The values of left atrium diameter (LAD),left ventricular end- diastolic diameter (LVEDD),inter ventricular septum thickness (IVST), left ventricular posterior wall thickness (PWT) and E/A were compared between both groups. Results Compared with control group,LAD,LVEDD,IVST and PWT values of observation group were increased,E/A values decreased, and the differences were significant (P 0.01).Conclusion For essential hypertension with normal LVEF,PTFV1- 0.03mm.s would be suggested as left ventricle diastolic function disturbance.


Accurate imaging from scattered field measurements is one of the main research topics in the field of nondestructive testing. Different methodologies for inverse scattering have been developed, ranging from backpropagation techniques to full-wave inversion methods. While far-field approaches are valid for the majority of the imaging systems, there are some scenarios where these approaches do not provide accurate modeling of the field radiated by the antennas of the imaging system. This results in some kind of distortion in the resulting output microwave images. To address this issue, proper characterization and modeling of the fields radiated by the antennas are required. This contribution proposes the use of an equivalent currents-based technique to characterize the transmitting and receiving antennas of the imaging sensor. The goal is to calculate accurately the field radiated by these antennas within the imaging domain, using it in the backpropagation algorithm. The methodology described in this contribution is supported by measurements for monostatic and multistatic configurations.


Severe aplastic anemia (SAA) is a syndrome of severe bone marrow failure due to hyperfunction of CD8+ T cells. While, the genetic background of SAA is still unknown. In this study, we tried to explore the possible genetic variants in CD8+ T cells of SAA patients.


Every one of the public nowadays have their presence in social media networks. The profile information of the social media account helps to understand nature of the user. Images, that are part of the profile information mostly characterizes the user and reveals much more about the user than the textual information. Such information extracted are used in many applications namely the employers, credit scoring, etc. This work has proposed Random forest regressor, Extra tree regressor and a dense neural network model for online user data scoring. Three submission using these models were made to the ImageClef Aware 2022 [1] task and has obtained 0.139 as Pearson Correlation Coefficient for testing.


Selected F3 and F4 lines of different origin were evaluated at high temperature (26° night and 35°C day) in the greenhouse along with several known heat-sensitive and heat-tolerant tomato (Lycopersicon esculentum Mill.) cultivars. A number of the selected lines had fruit set comparable to the tolerant cultivars Saladette, Ohio 7663, BL 6807, and Chico III. The expected greater fruit set of the tolerant cultivars vs. that of the sensitive cultivars was observed. High fruit set in this study was not associated with high seed number in the majority of tolerant cultivars evaluated.


Cyanogenic glucoside contents in some edible nuts and seeds (Sesamum indicum, Anacardium occidentale, Garsinia Kola, Sorghum bicolor,Vigna Unguilata) were all analysed to establishe their proximate compositions. The study showed that four (4) out of the six samples studied (Cashew nut, Bitter kola, Corn seeds and Cowpea seeds) contained hydrogen cyanide in the form of cyanogenic glycoside in quantities varying from 29.16mg/100g of dried samples for corn seeds to 56.70mg/100g for bitter kola, while two (2) of the samples sesame seed and sorghum seed tested negative showing the absences of hydrogen cyanide. The toxicological implications of the results have been discussed.


(57) Abstract Ultra low background multiphoton detectors for radioisotopes (20) have a background of about 1 count per day and can detect 1 atmole of material. The two opposing gamma and X-ray photon detectors each preferably have a scintillation crystal (22) and a photomultiplier (26). Interposed between the detectors are a separator (32) and a sample holder (34) for a sample (36) labeled with a radioisotope such as I 125 . Each detector converts radiation from the radioisotope into electrical output within the base (30), and the pulses are then processed for pulse shape analysis, discrimination between matches and discrepancies, and quantification of the radioisotope Is done. The detector materials and components have been selected to minimize background and are shielded from external radiation in the composite shield (55). Detectors operating on different principles and sample holders with different configurations may also be used. The device can be further configured to decompose to provide an image of the two-dimensional sample array.


In the late 192O's, Sulzberger returned to New York from his (raining abroad into a seething intellectual ferment of allergists and immunologists struggling with the rapidly unfolding concept of allergy and hypersensitivity. The young lion was ready—^with an enormous intellect, a mind as sharp as a prosector's knife and a tongue to match, and the special advantage of training with the pioneer geniuses of dermatologic allergy, Joseph ladassohn and Bruno Bloch. These were tuniLiltuous times and his writings and the discussions afterward reflected the excitement and confusion that existed. What follows is a historical review of his publications in scientific journals on the subjects of allergy and immunology. In it, I wish to illuminate and assess Sulzberger's unique role in the marriage of allergy to dermatology and the evolution of their offspring, the subspecialty of immunodermntology. Of his 134 papers published before 1944, 99 were devoted to various aspects of allergy and immunology. They contain the essence of his famous book, Dermatologic Allergy, published in 1940. To simplify the discussion I have divided the paper into 4 major topics, (1) atopic dermatitis, (2) allergy of infection, (3) clinical contact dermatitis and (4) experimental contact dermatitis with some minor


Based on anonymous tag based credentials and linear Mix-nets, this paper develops a scheme for e-cash systems that can be used in offline environments. The developed scheme makes e-cash holders anonymous while disabling them to use e-cash dishonestly. It also makes e-cash divisible and transferable. In detail, although no one except cash holders themselves can know correspondences between them and their e-cash, e-cash issuing authority can identify dishonest cash holders that had generated and/or spent e-cash illegitimately. In addition, cash holders can generate new e-cash of arbitrary values from their holding e-cash to make purchases of amounts less than original cash values. Also, cash holders can use e-cash that they had received from others as same as the one directly issued to them from the issuing authority.


Imaging subsalt is still a challenging task in oil and gas exploration. We have used magnetotellurics (MT) to improve the integration of seismic and gravity data to image the Wedehof salt dome, Northern Germany. Highresolution natural field source broadband MT data were acquired and enhanced the definition of the top and overhanging salt structures in addition to the description of the salt dome root. Salt boundaries show strong resistivity contrasts with the surrounding sediments and thus represent a good target for electromagnetic measurements, especially for mapping the top salt horizon. Using broadband array data acquisition and advanced processing techniques, difficulties with cultural noise sources could be solved. With integrated 3D gravity modeling focusing on the salt dome's flanks at intermediate depths, an improved model could be achieved. The revised salt geometries provided sound input to a seismic reprocessing and led to an improved imaging of the subsalt areas proven by subsequent exploration drilling. The integrated interpretation of MT, gravity, and seismics combines the strengths of the different physics, thus increasing the imaging reliability and reducing exploration drilling risks. In this case, we used a conservative workflow that includes a survey feasibility study with field noise evaluation and careful acquisition parameter testing at the beginning of the survey. Only with this could we overcome the cultural noise issues associated with the survey area being near large cities and their associated electromagnetic noise. Introduction Complex subsalt imaging is still one of the remaining difficulties in hydrocarbon exploration (Rowan et al., 2001). Extensive improvements have been made to tackle this problem with seismic new acquisition designs such as wide and full azimuth, long offsets, broadband acquisition, and advanced depth imaging such as reverse time migration and full-waveform inversion (e.g., Jones and Davidson, 2014; Warner and Guasch, 2016). However, not every subsalt problem has been solved, and many challenges remain. In areas where salt structures are extremely complex, project costs may still be prohibitively expensive, seismic signal-to-noise ratio may still be limited and therefore complicate subsalt imaging. For electromagnetics, salt is almost transparent because it is electrically isotropic and the salt-to-host rock boundaries are a perfect target with their high resistivity contrast (salt is usually several hundred-ohm-m resistivity and the surrounding sediments between 1 to 10 ohm-m). Located among many others, at the southern edge of the South Permian Basin in Lower Saxony, Germany, the salt dome Wedehof has been the subject of an intense geophysical search for hydrocarbon structures and related exploration drilling. Historically, the main object has been the search for hydrocarbons in the overhang regions and in the higher flanks of the structure. At later exploration periods, 3D seismic has been applied to obtain data in the deeper flanks and their downward extension into the Triassic series. The large uncertainty in the top salt imaging translates directly into large uncertainties (imaging, depth conversion) at base salt levels. The Wedehof High Resolution MagnetoTelluric (HRMT) project was designed to improve top salt interpretation and subsequently enhance seismic depth imaging of base salt and subsalt structures through an integrated geophysical approach. Figure 1 shows the location map of the survey. We anticipated severe electromagnetic noise problems due to the proximity of big cities (Bremen, Hannover, and Hamburg), airports, and electric trains; thus, we first carried out a feasibility study including 2D numerical modeling and detailed site inspection as well as locating a remote site for remote reference operation. Wintershall Dea, Ueberseering 40, 22297 Hamburg, Germany. E-mail: firstname.lastname@example.com (corresponding author). TERRASYS Geophysics, Baumeisterstr. 2, 22099 Hamburg, Germany. E-mail: email@example.com. KMS Technologies — KJT Enterprise Inc., 11999 Katy Freeway, Suite 160, Houston, Texas 77079, USA. E-mail: firstname.lastname@example.com. Formerly KMS Technologies, Via Liberazione 36, 29017 Fiorenzuola (PC), Italy. E-mail: email@example.com. Manuscript received by the Editor 22 January 2020; published ahead of production 6 April 2020. This paper appears in Interpretation, Vol. 8, No. 4 (November 2020); p. 1–10, 12 FIGS. http://dx.doi.org/10.1190/INT-2020-0026.1. © 2020 Society of Exploration Geophysicists and American Association of Petroleum Geologists. All rights reserved. t Special section: Europe — Diverse subsurface characterization challenge Interpretation / November 2020 1 1


An iodine laser amplifier system is designed and constructed to evaluate the concept of a space based solar pumped laser amplifier. A small laser oscillator which generates a 4—µS TEMoo pulse containing energy of 61.2 mJ and a 1.17 m long amplifier tube pumped by a flashlamp were used for the study. The energy extraction efficiency was observed to increase for lower pressure and weaker pumping. When the iodide fill pressure is 30 Torr, the maximum extractraction efficiencies are 43% and 63% for pumping energies of 1,410J and 977J respectively. When the gas fill pressure is reduced to 20 Torr for the pumping energy of 977J, the maximum energy extraction efficiency is near 100%.An iodine laser amplifier system is designed and constructed to evaluate the concept of a space based solar pumped laser amplifier. A small laser oscillator which generates a 4—µS TEMoo pulse containing energy of 61.2 mJ and a 1.17 m long amplifier tube pumped by a flashlamp were used for the study. The energy extraction efficiency was observed to increase for lower pressure and weaker pumping. When the iodide fill pressure is 30 Torr, the maximum extractraction efficiencies are 43% and 63% for pumping energies of 1,410J and 977J respectively. When the gas fill pressure is reduced to 20 Torr for the pumping energy of 977J, the maximum energy extraction efficiency is near 100%.


Minimum Requirements for Reporting Clinical Trials Evaluating the Therapeutic Potential of Platelet-Rich Plasma1 This letter to the editor1 addresses the work published by Shapiro and colleagues that described the results from a randomized controlled trial (RCT) evaluating platelet-rich plasma (PRP) as a treatment for androgenetic alopecia (AGA).2 PRP is a product of concentrating platelets, growth factors, and other molecules from a patient's blood, which is then injected into (often) the same patient to promote wound healing, decrease inflammation, and improve hair thickness and density. In the RCT by Shapiro et al, 5mL of PRP was prepared via centrifugation and injected 3-4mm into one side of the scalp of 35 AGA patients, with placebo injected into the other half. Both hair density and diameter increased in both PRP and placebo treated areas, with no significant difference between the two. Shapiro et al suggest this is due to 1) the spreading of the PRP treatment into the placebo area of the scalp, and 2) the micro-wounds created by injection, which has been shown to promote hair growth by itself. Shapiro et al also mention the difficulty of comparing their results to those from other trials, due to the heterogeneity of PRP preparations and treatment protocols.2 Sharun and Pawde utilize Shapiro and colleagues' work to suggest the need for implementation of a PRP classification or coding system, which would clarify the PRP preparation and application methods, as well as the exact concentrations of various cell types and molecules in the final PRP preparations.1 The authors refer to the new editorial policy regarding PRP treatment for the journal "Platelets," which states the aforementioned details are rarely fully defined, which is further complicated by the individuality of each PRP sample and the various available PRP preparation methods. Specifically, they mention that some bioactive factors have opposing effects on cellular regeneration, thus the need for analysis of the final PRP makeup.3 The authors also mention the work of Kon et al, who describe the ongoing debates about the role of specific cells in PRP and how their concentration may affect treatment efficacy: 1) platelets, specifically the mean platelet volume, may reflect the capability of platelets to store growth factors; 2) leukocytes, which may be detrimental due to their pro-inflammatory capabilities or could be manipulated to become anti-inflammatory; and 3) erythrocytes, which may also have a detrimental effect.4 Shapiro and colleagues responded to this letter in agreement with the need for more details regarding PRP protocols, and encourage further research into the role of PRP constituents in hair growth, while warning against further split-scalp studies.5 Columnist's note: This cordial communication between scientists exemplifies the value of sharing knowledge and opinions in the literature. There is much left to be elucidated regarding PRP, its preparation, application, and constitution. A PRP categorization system that includes biochemical and biological analysis of the final PRP product would be a useful addition to PRP research.


Fabric hand evaluation, previously applied to men's suiting, is used here to assess the touch or feel of nonwoven fabrics. In this method, fabric mechanical property parameters are converted by a first conversion equation (equation type I ) to numbers (the hand value or Hv) that express three primary hand values (the Hv) such as stiffness, etc., which are the primary factors characterizing fabric hand. Subsequently, these hand values are converted into a total fabric quality number (the total hand value or THV) by a second conversion equation (equation type II), which should then correlate well with subjective hand. The three primary hand attributes defined pre viously for men's suiting are also assumed to apply to nonwoven fabrics to characterize their hand. Primary hand values for nonwovens were obtained using the same equation as the men's suiting equation with minor modifications. Subsequently, two evaluations were performed—direct application of the men's suiting equation (type II ) to the nonwoven fabrics to derive their THV and construction of a new type II equation for the THV of nonwoven fabrics. Both equations can be used to predict nonwoven THV, but the predictive ability of the new equation is better than that of the previous one, and its prediction error is smaller than that of the subjective judgments made by average individuals. The correlations between THV and mechanical parameters were also examined; MMD, a frictional property parameter, was the most important param eter affecting THV.


Background: The existence of partnerships between the health system and other organizations, especially city councils and municipalities, which have inherent and legal duties in this regard, is of particular importance in the promotion of public health.
Objectives: The present study aimed to assess the status of Health System cooperation with City councils and municipalities in Iran based on rules and documents.
Methods: Altheide's document analysis model (sample selection, data collection, data organization, data analysis, and reporting) was used to prepare and analyze the documents pertaining to the status of Health System cooperation with city councils and municipalities. The documents were classified at three levels of national rules, policies, and guidelines; Ministry of Health (MOH) and city council approvals; and eventually Tehran municipality's measures.
Results: A total of 78 documents were analyzed, including 17 documents at the level of national rules, policies, and guidelines; 8 documents at the level of Ministry of Health and city council approvals; and 53 documents at the level of municipality's measures.
Conclusion: There are adequate legal capacities for designing, planning, executing, as well as creating interaction and cooperation between the health system and other organizations, especially city councils and municipalities. Moreover, the motives behind creating purposeful and scheduled cooperation and participation are evident among the officials of the health system and city councils and municipalities. Some mechanisms have been established for cross-sectoral cooperation between the health system and other health-related bodies. Nonetheless, these structures lack the necessary competence, appropriateness, and adequacy to create the desired partnership. Moreover, sufficient attention is not devoted to existing capacities in municipalities and the city council. Accordingly, it is necessary to have a fundamental review on the available structures and enough attention has to be paid to the evident and hidden legal capacities in city councils and municipalities, as well as the Ministry of Health, to design an appropriate structure, create competent interaction, and provide more cooperation between the two organizations.


Gelatin has been extracted from fivelined threadfin bream fish using 0.05 M acetic acid. Extraction process was carried out at varying temperature of 60, 80 and 95oC for 3 h. Result indicated that extraction at 80oC showed the highest gel strength (187 Bloom) with viscosity of 12 cP. In fact, it produced the lowest yield (30.45%) with melting point of 31.67oC. Higher gelatin yield was shown by extraction at 95oC (38%) and the higher melting point was shown by extraction at 60oC and 95oC (around 34oC). Amino acids composition of the selected gelatin was similar to that of bovine gelatin. At concentration of 1-3% (w/v), emulsion stability index (ESI) of fish gelatin was lower than bovine gelatin. Emulsion activity index (EAI) was dependent on the gelatin concentration, at level of 1% and 2%, EAI of fish gelatin was considerably higher than bovine gelatin. At gelatin 3%, EAI of fish gelatin and bovine gelatin was similar. It suggests that the gelatin from fivelined threadfin bream skin has comparable physicochemical properties against bovine gelatin. Keywords : Fivelined threadfin bream, gelatin, physicochemical properties.


Although the etiology and pathogenesis of Multiple Sclerosis (MS) remain elusive, accumulating evidence indicates that MS is a chronic inflammatory disease with an autoimmune component, mediated by autore‐active T lymphocytes specific for myelin antigens. The triggering T cell autoantigen has not been identified yet, but recent immunological studies in MS and parallel experiments in experimental allergic encephalomyelitis (EAE), the animal model of MS, have indicated that myelin basic protein (MBP) can be considered as one of the major candidate autoantigens in the pathogenesis of the disease. Based on these observations, several therapeutic strategies have been developed aimed at the specific elimination or inactivation of MBP reactive T cells in MS. One of these approaches involves the immunization of MS patients with autologous attenuated autoreactive T cells to induce an immune response specifically targeted at these autoreactive T cells. This method, termed T cell vaccination, has been shown to prevent and treat EAE. We have recently conducted a pilot trial of T cell vaccination in a limited group of MS patients to evaluate the immunological responses to the injected cells. The data obtained indicate that this type of vaccination induces an effective anti‐clonotypic T cell response leading to a specific depletion of circulating MBP reactive T cells. Preliminary data on the clinical effects are promising, encouraging further clinical trials. © 1996 Wiley‐Liss, Inc.


For the insulating joint of long distance pipeline,the relative design scenario is presented according to the structures' requirements in higher insulating capacity, sound sealing performance, excellent rigidity, longer service life and maintenance-free. The technical issues to be focused on are given in selection of structures, installation of lining or coating used for the non-conductive medium, dimensional stability between the sealing groove and sealing gasket,quality control of welding process,injection time of up-down filler and connection between the joint and pipeline.


Motivated by the need of developing numerical tools for the simulation of plant root growth, this article deals with the numerical resolution of the C-Root model. This model describes the dynamics of plant root apices in the soil and it consists in a time dependent advection-reactiondiffusion equation whose unique unknown is the density of apices. The work is focused on the implementation and validation of a suitable numerical method for the resolution of the C-Root model on unstructured meshes. The model is solved using Discontinuous Galerkin (DG) finite elements combined with an operator splitting technique. After a brief presentation of the numerical method, the implementation of the algorithm is validated in a simple test case, for which an analytic expression of the solution is known. Then, the issue of the positivity preservation is discussed. Finally, the DGsplitting algorithm is applied to a more realistic root system and the results are discussed. Keywords-Time dependent advection-reactiondiffusion; Operator splitting; Discontinuous Galerkin method; Plant root growth simulation;


Herein we report the presence of unusual structures found in a sputum smear from a 67-year old man who was admitted to hospital for possible pneumonia. He had a history of melanoma (unknown primary site) metastatic to his lungs and brain. The patient was afebrile. A CT chest showed bilateral patchy pulmonary infiltrates. An induced sputum sample was sent to the cytopathology and microbiology laboratories. The microbiology laboratory identified rare epithelial cells and polymorphonuclear cells with very rare gram-positive Cocci in pairs. The culture grew moderate normal respiratory flora, but no fungi. In addition, throat and blood cultures were negative. Initially, he was treated with azithromycin and dexamethasone. However, the patient developed a pulmonary embolism with worsening of respiratory symptoms and hypoxia. He subsequently developed an acute brain hemorrhage and died. No tissue was procured, and an autopsy was not performed. The sputum smear, stained by the Papanicolaou method, contained unusual elements comprised of elongated ribbon-like structures with short rounded branches close to 90 angles (Figures 1A, B). These elements stained moderately with a Grocott methenamine silver stain (Figure 2). There was no cell block available. Due to this fungal-like cytomorphology and considering the immunosuppressed status of this patient, the presence of fungal elements, mainly Mucor spp., was initially considered. However, the concomitant presence of vegetable cells in this sputum specimen raised concerns about sample contamination. Figure 3 shows typical plant cells (black arrow) characterized by a rectangular shape and thick cell walls. Figure 4


By using a broadband fiber mirror (BFM), a wavelength tunable erbium‐doped fiber laser (TEDFL) is demonstrated composed with tunable fiber Bragg grating (TFBG). The BFM acts as a broadband reflector both for the lasing signal and pump source. At pumping power of 100 mW, stable laser output power of 21.35 dBm is obtained at a low threshold pumping power of 4.7 mW. A side mode suppression ratio (SMSR) of 57.9 dB and 16 nm wavelength scan range are demonstrated using a single TFBG. The tunable fiber laser may be a good candidate for vast applications in optical network technologies. © 2008 Wiley Periodicals, Inc. Microwave Opt Technol Lett 50: 1722–1724, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.23510


This paper describes a regulation structure for the BUCK converter without galvanic isolation. The feedforward control structure with an adaptive feedback loop improves the dynamic properties of the entire inverter. It also ensures higher resistance of the regulation structure against changes of the input variable. The control structure has been designed for traction converters that are supplied with voltage from the traction dc bus which is characterized by significant rises and falls. It may occur especially during transient events, for instance, locomotive's drift in pull or when the locomotive changes its mode from a drive to a brake mode and vice-versa.However, this theory and principles of the regulation structure can be used also in other types of DC/DC converters. What is more, it is possible to use it also for DC/DC converters with galvanic isolation after adaptation for the particular application.


The objective of this paper is to propose a modified optimal sliding mode control method for the hydraulic anti-lock braking system of a vehicle to achieve both robustness and optimal control performance. The longitudinal dynamic model of a vehicle, tyre model and hydraulic anti-lock braking system model are established, and the weakness of the common optimal sliding mode control method in designing the anti-lock braking system controller is analysed synthetically. The analyses form the basis for tracking an ideal slip ratio. A new modified optimal sliding mode controller is proposed to regulate the hydraulic anti-lock braking system for a better braking performance and robustness: the optimal sliding mode manifold function includes several virtual damping elements and infinitely small-sized items to meet the working conditions of the current optimal sliding mode control method. The control results of the proposed controller are compared with those of the common sliding mode controller. Simulation results under various road conditions demonstrate that the modified optimal sliding mode controller not only has strong robustness against uncertainties in the road adhesion coefficient but also achieves better control performance of the slip ratio.


Objective To study influences of IL_10 on the cytokine in acute lung injury in rats induced by endotoxin.Methods Twenty-four SD rats were divided into three groups:control group,experiment group and treatment group.LPS was injected through tail vein in experiment group,LPS and IL-10 were injected through tail vein in treament group,and normal saline was injected through tail vein in control group.Expression of TNF-α,IL-1β,IL-6 mRNA in the lung tissue and levels of plasma TNF-α,IL-1β,IL-6 in the three groups were measured.Lung tissue was also used for pathological examination.Results The mRNA expression and the plasma levels of cytokines in experiment and treatment groups were significantly higher than those in control group(P0.01),while experiment group were significantly higher than treatment group(P0.05).The degree of lung injury in treatment group was significantly attenuated.Conclusion IL-10 can inhibit the expression of TNF-α,IL-1β,and IL-6 mRNA in the lung tissue,and attenuate pathological renal tissue injury.IL-10 may be effective in treating ALI.


In this article, the main directions that determine the efficiency of the transport-logistics system, the interdependence of the concepts of the transport complex, the transport-logistics system and the logistics infrastructure, as well as the main factors affecting the choice of the type of transport, the assessment of various types of transport is presented, the specific features of optimizing the costs of cargo delivery are highlighted , the approaches to evaluating the efficiency of the transport-logistics system and directions for improving its efficiency are shown.


Unhealthy life-behaviors such as dietary habits, lack of exercise, drinking large amount of alcohol and smoking cause obesity, hypertension, diabetes, dyslipidemia, cardiovascular disease (CVD). These are also closely associated with chronic kidney disease (CKD). CKD is characterized by proteinuria and low glomerular filtration rate (GFR). Independent of GFR, proteinuria is an important predictor of ESKD. Few studies have assessed which is the most clinical impact among the unhealthy life-behaviors: skipping breakfast, snacking, late-night dinner, smoking, heavy alcohol intake and lack of exercise habits for proteinuria in normal renal function patients.

 This cross-sectional study included 29,780 normal renal function patients: eGFR≥60 mL/min/1.73 m2 and no history of kidney diseases who underwent health checkup at the Physical Checkup Center of Sumitomo Hospital. The endpoint of this investigation is defined as dipstick proteinuria of≥ 1+. To assess the association of life-behaviors and the presence of proteinuria, their odds ratios were calculated in adjusted univariable and multivariable logistic regression model. Multivariable logistic regression model was performed by not selected items, the same with univariable model. We would like to investigate the most impact unhealthy life-behavior for the proteinuria.

 Among 29,780 total study subjects (male: 60.3%; mean age: 49±11 years), 1,118 (3.75%) subjects were shown as urinary protein above 1+. The presence of unhealthy dietary life-behaviors: skipping breakfast, snacking and late-night dinner was 5,293 (17.3%), 3,899 (13.1%) and 11,231 (37.7%), respectively. About sleeping duration, the population of <6 hours, 6-8 hours and >8 hours were 12,027 (40.4%), 17,236 (57.9%) and 517 (1.7%). The population of exercise habits: over 3 days/weeks, 1-2 days/weeks and none were 5,138 (17.3%), 9,375 (31.5%) and 15,237 (51.3%), suggesting half of them did not have exercise habits. About smoking habits, the population of current smoking, past smoking and never smoking were shown 6,445 (21.6%), 8,459 (28.4%) and 14,876 (50.0%). In addition, about alcohol amount per day, the population of over 60g, 40-60g, 20-40g and 0-20g were 1,840 (6.18%), 4,504 (15.1%), 6,727 (22.6%) and 16,709 (56.1%).
 To investigate the impact of life-behavior for proteinuria, we obtained odds ratio of adjusted multivariable logistic regression model. In multivariable regression, among the life-behavior: skipping breakfast, current smoking, alcohol amount (ethanol over 60 g/day), none of exercise habits and snacking were strongly associated with the prevalence of proteinuria (skipping breakfast, adjusted odds ratio 1.45 [1.26, 1.68]; current smoking, 1.35 [1.14, 1.59]; alcohol amount (ethanol over 60 g/day), 1.35 [1.08, 1.69]; none of exercise habits, 1.29 [1.07, 1.57]; snacking, 1.23 [1.04, 1.46]). In addition, among the history of medical history, diabetes mellitus, hypertension and dyslipidemia were significantly associated with the prevalence of proteinuria (diabetes mellitus, adjusted odds ratio 2.39 [1.93, 2.96]; hypertension, 1.83 [1.53, 2.17]; 1.22 [1.03, 1.45]).

 Among the unhealthy life-behaviors, skipping breakfast is the most impact factor for the presence of proteinuria.


The paper brought to light a previous result of the author, used in the design of hydraulic servos actuating flight controls of the airplanes IAR 93 and IAR 99. The results highlights the importance of the the kinematics of the rigid feedback linkage of the hydraulic servo in an aeroservoelastic frame.


This study assessed the impact of intercultural human resource management practices (Recruitment and Selection practices, Employee empowerment practice, and Compensation practice) on employees' satisfaction in food and beverages MNCs in Nigeria. The study adopted descriptive survey research design. The target population comprises 6,356 staff of quoted food and beverages MNCs in Nigeria. Taro Yamane statistical formulae was used to determine the sample size of 1,568. Purposive sampling technique was used to determine the respondents which included Nigerians and Other Nationals working in the quoted food and beverages MNCs. A structured survey questionnaire was adapted, validated, and used for the construct ranged between 0.61 and 0.93. The response rate to the 1,568 copies of the questionnaire administered was 74%. Data were analysed using descriptive and inferential (Student T-test of multiple regression analysis) statistics. Hypotheses were tested at 0.05 level of significance using SPSS 20. Findings revealed that, Recruitment and Selection practices, Employee empowerment practice, and Compensation practice had significant positive influence on employees' satisfaction among Nigerians and Other Nationals in food and beverages MNCs in Nigeria (β = - .025 - .441 ; P< .000 ; β = - .025; P> .343); (β = - .124 -.514; P< .000): (β = .168 - .299; P< .000: β = -.15; P> .566; - .225 -.246; P< .000): (β = -.144 -.421; P< .000; β = -.004; P> .886): (β = -.105 - .456; P< .000 -.001) respectively, except for power distance that had negative and insignificant influence on employees' satisfaction among Nigerians with respect to recruitment and selection and collectivity and individuality that had negative and insignificant influences on employees' satisfaction among Nigerians with respect to compensation and employee empowerment.


As material science is integrated into medical science as in other fields, the variety, development and usage areas of biomaterials increase. One of the biomaterials in this variety is NiTi alloys. This study was focused on the coating of TiO2 layer by using the method of Micro Ark Oxidation with the aim of the improvement of surface and mechanical properties of Shapedmemory and bio material NiTi alloy. Structural properties of the coatings were analysed by of SEM and XRD. In vitro ability was investigated by soaking the coated NiTi samples in simulated body fluid (SBF) at temperature 37 °C for various time periods. After soaking, Ni+2 release was applied to the media where coated and uncoated shape-memory NiTi samples are available, and its control was made by means of ICP-MS device. The results also show that Toxic and carcinogenic effects of Ni+2 release is significantly reduced by the TiO2 coating. Thus, it is observed that the properties that limit the use of NiTi alloys has been substantially fixed by MAO coating. It was found that the bioactive properties of the TiO2 coated NiTi substrate increased by MAO method and at the end of the 72 hour, there was no statistically any cytotoxicity in cell viability compared to the NiTi substrate


Seventy subjects with either no, mild, or definite evidence of pulmonary abnormality on screening studies volunteered to have detailed pulmonary function tests (PFTs), respiratory questionnaires, physical examinations, and 113m indium aerosol-inhalation lung imaging performed. Also, 22 and 52 of these subjects underwent 133 xenon ventilation and lung perfusion imaging with 99m technetium-labelled macroaggregated albumin, and 56 had chest x-ray examinations performed. Results of the radionuclide lung-imaging procedures were compared with those of conventional PFTs and other clinical diagnostic procedures used to identify chronic obstructive pulmonary disease (COPD). Abnormal radioaerosol patterns were found in 32 of 33 subjects with abnormal findings on PFTs, whereas results of PFTs were abnormal in only 32 of 46 subjects with abnormal aerosol deposition. Aerosol lung images were abnormal more frequently than respiratory questionnaire responses, findings on physical examination, chest x-ray films, and perfusion lung images and with approximately the same frequency as 133 xenon ventilation scintiscans. These results suggest that radioaerosol lung imaging may be a more sensitive indicator of early COPD than other diagnostic procedures, including maximal midexpiratory flow rates, single-breath nitrogen washout, and closing volume. Further studies are required to determine the physiologic and pathologic significance of isolated aerosol lung-imaging abnormalities.


The market for protective pants is large. Still these pants have developed in a very slow pace comparing to, as an example, sportswear. The main material used for these pants, cotton, has some negative characteristics that could be avoided if a synthetic fabric was used instead, but this has so far not had any success.The purpose with this study has been to get a picture over the market for protective clothing and research the carriers attitude towards synthetic material. The requirements that a synthetic material must achieve, so that the costumer will buy these pants instead of a pair of conventional protective pants, has also been examined. The study is based on interviews on product developers and a survey of carriers to get an idea about the business. These answers have been used to form a plan of marketing and a list of requirements.The result shows that the new material must exceed the conventional material. The material should be named and marketed in a way that the product appears innovative and technological. It is important that the material is not associated with the negative image of synthetic materials. To address to a younger target group seems suitable since these people are probably more receptive for new innovations. The marketing should be focused on product and place. To reach the customers it is important to find and use new ways of distribution such as personal sales. Since the selection of protective clothes is today quite similar, a company that focuses on design and innovation could be able to reach great success.


We conducted a genome‐wide association study (GWAS) of systolic and diastolic blood pressure (BP) in Amish subjects and identified several SNPs to be robustly associated with BP in a serine/threonine kinase, STK39. Identifying STK39 as a hypertension susceptibility gene is of great biological implication as emerging evidence indicate that STK39 encoded protein, SPAK, interacts with WNK kinases and cation‐chloride transporters in cell‐based assays and participates in an essential sodium‐transport pathway. We demonstrate that in vivo, SPAK is expressed in the distal nephron, where it may interact with these proteins. While none of the associated SNPs from GWAS alter protein structure, we identified several BP‐associated SNPs located in intronic conserved sequence elements (CEs). When tested in reporter gene assays, one of these CEs demonstrated allele‐specific in vitro transcription activity. Oligonucleotides from this CE also showed allele‐specific binding to nuclear protein(s) in electrophoretic mobility shift assays. Hence STK39 may influence BP by allele‐specific DNA‐protein interaction that modifies SPAK expression and renal sodium excretion.


Introduction: The minimally traumatic retrieval implant technique is a treatment that uses a tapered screw counterclockwise device. This tool can break the osseointegration and retrieve the implant easily. Objective: The aim of this paper is to show a clinical case report where this technique was used in implant failure and to show the advantages and disadvantages of other treatment alternatives. Conclusions: This new approach suggests that this explantation can preserve the peri-implant bone tissue and the adjacent teeth, there is a reduction of treatment time and in the morbidity associated with bone reconstruction. It seems an effective technique for removal of implants, ensuring predictability to retreatment.


PURPOSE: A source driver for a liquid crystal display(LCD) panel improved in a voltage characteristics of an output terminal is provided to easily realize the source driver without adding an additional component by utilizing the resistor string used in a conventional method. CONSTITUTION: A source driver for the LCD panel improved in a voltage characteristics of an output terminal includes a plurality of digital-to-analog(D/A) converters(20a-20d), a plurality of amplifiers(21a-21d), a plurality of output pads(24a-24d), a plurality of first switches(22a-22d), a plurality of second switches(23a-23c), a resistor string(R-string) and a third switch(25). The plurality of amplifiers(21a-21d) is connected to the D/A converters(20a-20d). The plurality of output pads(24a-24d) applies the voltage to the LCD panel. The plurality of first switches(22a-22d) connects the plurality of amplifiers(21a-21d) to the plurality of output pads(24a-24d). The plurality of second switches(23a-23c) is connected to the plurality of output pads(24a-24d), respectively. The resistor string(R-string) is connected between the power voltage and the ground terminal to output the divided apply voltage. And, the third switch(25) is connected between the resistor string(R-string) and the plurality of output pads(24a-24d).


OEJECTIVE:To analyse the chemical constituencts of essential oils obtained from Saussurea tridactyla and Saussurea medusa .METHODS:Using high resolution GC MS technique.RESULTS:30 of 53 and 31 of 57 separated components from essential oil of Saussurea tridactyla and Saussurea medusa were identified by MS,respectively.CONCLUSION:The most abundant constituents in both essential oils were similar.


Background: Upfront autologous stem cell transplantation (ASCT) in multiple myeloma (MM) following induction therapy has been demonstrated to improve progression free survival (PFS) and overall survival (OS). Consideration of transplant eligibility involves assessment of age (typically <70 years), co-morbidities and frailty. In Australia and New Zealand, approximately 70% of all MM patients aged <70 years undergo upfront ASCT compared to approximately 6% aged 70-75 years (Bergin, MRDR Data). We aimed to review the patterns of transplantation in Australia and New Zealand in patients ≥70 years of age and examine survival outcomes and predictors of survival in this cohort.
 Methods: We analysed 8786 MM patients who received ASCT in Australia and New Zealand between 2001 and 2019. 630 (7.2%) were ≥70 years of age. As there was missing data in the registry, additional data was obtained for 466 ≥70 years of age from 20 sites (performance status (PS), melphalan dose and creatinine clearance (CrCl)). These sites were selected on the basis of number of eligible patients in the registry. Kaplan-Meier analysis was performed to determine PFS and OS. Univariate and multi-variate analysis was performed using Cox proportional hazard model to determine predictors of OS.
 Results: The baseline patient and disease characteristics are presented in Table 1. The total number of ASCT procedures performed for MM has increased over the study period, and the proportion of ASCT patients ≥70 years has also increased from 5% in 2000-2004 to 11% in 2015-2019 (Figure 1). 33% of patients ≥70 years of age received reduced dose melphalan (140mg/m2 versus 200mg/m2) compared with 10% of patients < 70. Poor PS (ECOG > 1/Karnofsky Performance Score < 80) and CrCl did not significantly predict dose reduction of melphalan.
 At a median follow-up of 3.8 years, median PFS was 3.3 years (95% CI 2.9-3.8) for those aged ≥70 and 3.4 years (95% CI 3.2-3.6) for those 60-69 (P =0.7). Median OS in those aged ≥70 was 5.6 years (95% CI 4.9-6.3) compared to 6.2 years in those 60-69 (5.8-6.6 years) (P = 0.01). There was no difference in median time to platelet and neutrophil engraftment in patients aged ≥ 70 compared to those < 70. There was no significant difference in transplant related mortality at day 100 in those ≥70 years (1.8%, 95% CI 1-3%) compared to those < 70 (1%, 95% CI 0.7-1.2%) (P = 0.07).
 OS in all patients aged ≥ 70 (n = 630) was significantly better in patients transplanted between 2010-2019 (n = 451) compared to 2000-2009 (n = 179) (HR 1.62, 1.20-2.19, P = 0.002) (Figure 2) likely correlating with access to bortezomib based induction in 2011/2012 in Australia and New Zealand, and is reflected by an increased proportion of patients achieving a partial response (PR) or better at time of ASCT (Table 1). Increased access to novel agents in the relapsed/refractory MM patients as well as improvements in supportive care also may have contributed. On univariate analysis, other predictors of OS in older patients were poor PS (HR 2.44, 95% CI 1.23-4.81, P = 0.01), higher risk disease (Stage III using Durie-Salmon, ISS or R-ISS) (HR 1.42, 95% CI 1.01-2.00, P < 0.042) and failure to achieve a PR prior to ASCT (HR 1.71, 95% CI 1.01-2.87, P = 0.05). On univariate analysis, melphalan dose did not predict OS (HR 1.35, 95% CI 0.89-2.05, P = 0.2).
 Multivariate analysis of determinants of OS was performed for the patients in whom we obtained the additional data. Because of missing data for both PS and stage, multivariate analysis incorporating all variables of interest (decade of transplant, melphalan dose, disease status at transplant, CrCl, PS and stage at diagnosis) could only be performed in a subset of patients (n = 163) (Table 2). In this cohort the only significant predictor of OS was poor PS (Table 2).
 Conclusion: There is increasing utilisation of upfront ASCT in patients aged ≥ 70 in Australia and New Zealand. OS in this group of patients has significantly improved over the study period in keeping with access to bortezomib based induction and novel agents in the relapsed and refractory setting. In a highly selected group of patients ≥70 years of age, ASCT is feasible and associated with excellent PFS and OS. On multivariate analysis, PS was the only predictor of OS. The prospective use of established co-morbidity and frailty scores in assessing transplant eligibility in older patients warrants further evaluation.

 Harrison: Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Janssen-Cilag: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; BMS: Consultancy, Honoraria; Haemalogix: Consultancy; AbbVie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; GSK: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; CRISPR Therapeutics: Consultancy, Honoraria; F. Hoffmann-La Roche: Consultancy, Honoraria; Janssen: Honoraria; Novartis: Consultancy, Honoraria, Patents & Royalties: wrt panobinostat; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding. Spencer:AbbVie, Amgen, Celgene, Haemalogix, Janssen, Sanofi, SecuraBio, Specialised Therapeutics Australia, Servier and Takeda: Honoraria; Celgene, Janssen and Takeda: Speakers Bureau; AbbVie, Celgene, Haemalogix, Janssen, Sanofi, SecuraBio, Specialised Therapeutics Australia, Servier and Takeda: Consultancy; Amgen, Celgene, Haemalogix, Janssen, Servier and Takeda: Research Funding. Mills:Celgene: Honoraria; Novartis: Honoraria, Other: Meeting sponsorship; AstraZeneca: Honoraria; Abbvie: Membership on an entity's Board of Directors or advisory committees. Hertzberg:Takeda: Honoraria, Membership on an entity's Board of Directors or advisory committees; Roche: Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Support of parent study and funding of editorial support; MSD: Membership on an entity's Board of Directors or advisory committees; Gilead: Membership on an entity's Board of Directors or advisory committees; BMS: Honoraria; Abbvie: Honoraria; Janssen: Honoraria, Membership on an entity's Board of Directors or advisory committees. Sidiqi:Amgen: Honoraria; Janssen: Honoraria; Celgene: Honoraria, Other: Travel grant. Kalff:Celgene: Honoraria; Janssen: Honoraria; Amgen: Honoraria; CSL: Honoraria; Roche: Honoraria. Hamad:Novartis: Honoraria; Abbvie: Honoraria.


This chapter discusses how measurement activities were central in forming some of the most basic ideas of the physical sciences. It should be observed that this infatuation with measuring led to the neutralization of concepts as well as their creation. Temperature had less human meaning after the experimental physicists laid hold of it. In the natural sciences, Ernst Mach's positivism was especially influential among experimenters. The resonance of the positivist mania for quantification with vast social ambitions for science is exemplified best of all by the career of Karl Pearson. From the early 1890s until his death more than forty years later, Pearson harnessed his prodigious talents to the development of a statistical method and its application to biological and social questions. The chapter then considers the standardization of measurements.


In this study, quantitative and qualitative methods were used to identify factors that best explain variations in state appropriations for Carnegie Public Research I Universities during the late 1990s. A combination of cultural, political, and institutional factors emerged as critical elements accounting for differences in support including institutional commitment to public service and outreach, strength of postsecondary education governance structure, and gubernatorial and legislative support.


Now,in college,many students can't speak English smoothly when they talk each other.To solve this problem is demand of development of society and era.The current teaching methods for reading and comprehension should be changed and the spoken language teaching and bilingual teaching should be strengthened so that the students can grasp spoken language in the process of the obtainment of the knowledge.


Energy Dispersive Spectrometry (EDS) is an ubiquitous method of elemental analysis for SEM, TEM, and STEM applications. The elements of interest are generally quantified without standards using theoretical calculations or by using standards that are high purity specimens of the elements measured. However, EDS is often used to determine a small percentage of an element in a matrix. The accuracy and limit of detection of these low concentration measurements has not been established. An earlier report proved the concept that a cross section high dose BF2 implanted specimen could provide a standard for EDS measurement of F. This study extends this quantification approach to transition elements of importance to the semiconductor industry. The Fe and Co standards were created by high dose ion implantation. For ions implanted into silicon, a dose of lxl016 atoms/cm2 results in a peak concentration of approximately lxl021 atoms/cm3 or 2% atomic. The exact concentration can be determined using methods such as Rutherford Backscattering Spectrometry (RBS) and Secondary Ion Mass Spectrometry (SIMS).


Abstract This essay explores the imbrications between queer precarity and social reproduction from the perspective of homonormative division of labour. Contextualizing the emergence of China's HIV/AIDS economy and its reliance on queer intimate labour, it argues that the homonormative division of labour are part and parcel to maintain and nurture the economic, political structures of LGBT liberalism. Instead of providing 'local case' of homonormativity, this paper connects the normalizing power on sexuality and bodies to the larger geography of transnational labour division and conditions of labour precarity, providing an analysis of South-focused political economy of homonormativity. Arguing against viewing precarity as an overarching global phenomenon, this essay centres on lived experiences of the queer 'precariat' and highlights the contradiction and interplay of agency and conformity. Reclaiming the Chinese queer lexicon tongzhi (comrades), not only as a sexual identity, but as queer sociality where desires and work converge, this essay cautions against narrowly defined but broadly circulated concepts such as 'oppression', 'resistance', 'social movement' and 'community' that are predominantly derived from Western centric political imagination and activist space.


Abstract: A magnetic field applied to a crystalline solid causes the electron states on the Fermi surface to circulate along the orbits located on the planes normal to the applied field. For a sufficiently weak field the separate orbits can cover the whole closed Fermi surface. A suitable parameterization of the states on the orbits should be done in a different way than a conventional parameterization applied for the electron states by Bloch. This new kind of parameterization becomes quite simple when the magnetic field is assumed to be directed parallel to one of the crystallographic axes. Computationally, a new description of the electron states on the Fermi surface becomes on many occasions more flexible in its use than the Bloch's one. The simplifications concern mainly an examination of the curvature parameters of the Fermi surface and extremal properties of the electron observables, for example that of electron velocity. Solely the states in the cubic crystal lattices were considered as examples.


A new experimental technique has been developed to measure directly the rotational rate of a molecule connecting two portions of an electron paramagnetic resonance (EPR) spectrum, by a method which is independent of any factors in the Hamiltonian (such as A or g tensors) or the particular mechanisms of relaxation. Perdeuterated [ 15 N] TEMPOL and CTPO in glycerol-water mixtures and spin-labeled hemoglobin were studied using the time domain technique of pulsed saturation recovery electron double resonance (SR-ELDOR) in the 0.1-10-μs motional time regime


The article examines the characteristics of social networks used by Russian Internet users. It presents the results of a discourse on the possibilities and prospects of the study of social networks. Methodological approaches for researching self-presentation and identification in social networks are defined.


This study finds through statistical analysis the level of political awareness among women residing in Chennai. The awareness level on politics for women can be influenced by many factors like age, education, caste, class, religion, family background, place of residence, marital status and much more. However, this study takes into consideration age, education, occupation, and marital status alone. The role of women in politics is imperative. Political participation of women in large numbers is essential to show numerical strength as well as to get things in favor of them at the policy level. Participation is not restricted to voting alone. Seeking political information, discussing and debating about politics, sharing political information, and participating in political campaigns, rallies, etc, are other ways of involvement to be politically empowerment. For which political awareness is indispensable. The present study is interested in finding out the political awareness level of women in Chennai.


This summary is part of a new ISER initiative, Investing for Alaska's Future, underwritten by a grant from Northrim Bank and in partnership with the University of Alaska Foundation. Go to www.iser.uaa.alaska.edu for more information. What drives Alaska's economy is new money: money coming in from outside the state. How big the economy is, and how much it grows, depends on how much new money comes in. New money comes from " basic " sectors— the sectors that are the basis for all jobs and income across Alaska. They are, in effect, the gears driving the economy. Alaska has eight main basic sectors, but the number of Alaskans they employ directly is small, compared with the number of jobs they support indirectly. Figure 1 shows numbers and shares of jobs for Alaskans that the federal government, the petroleum sector, and the other basic sectors generated on average between 2004 and 2006. The numbers for any specific period aren't as important as the percentages, which don't change much from year to year. • If the flow of federal and petroleum money disappeared overnight, two-thirds of the jobs for Alaskans would also disappear, because each of them supports a third of those jobs. • Alaska's other basic sectors combined support about a third of jobs for Alaskans. The seafood, mining, and timber sectors produce commodities that are exported. The tourism and international air cargo sectors sell services to people from outside Alaska. Federal retirement checks and investment income Alaskans collect from outside sources also generate jobs. How is it that the federal government and the petroleum sector support most jobs for residents, and several other sectors support the rest? This summary, based on a longer paper (see back page), is a unique analysis of how the basic sectors drive the economy. Instead of looking just at jobs in a specific activity—seafood processing, for instance—we allocate all the jobs throughout the economy to the basic sectors that support them. This method gives a clearer picture of the structure of the economy, but it may produce different numbers than other methods. Here we use jobs for residents to measure economic contributions—a reasonable measure but not the only one, as we discuss in the full paper. We analyze just jobs for Alaska residents, even though many non-residents also work here. They don't typically spend their paychecks in Alaska, so they don't add as much to …


1. Election of the Executive Board It is proposed that the present executive board for the purpose of continuity is reelected for another period of three years. The general assembly unanimously agrees with this proposal. For the period 1999-2002, Vappu Taipale will be president, Jan Graafmans secretary general / treasurer and Richard Pieper past vice-president. The executive board is completed with Neil Charness in the position of vice-president and chairman of the next conference (USA, 2002). 2. Election of the standing committees After a short discussion the following standing committees are established: Publications, In- and external communication, Education, Research and development, Industrial relations, and Conference. The present committees are to be seen as precursors of the more extended standing committees in the near future. Each committee is expected to formulate its own working programme and recruit active members from within the Society. Council members were encouraged to find good representatives in the committees from their own country in case they themselves would not be able to invest appropriate time and attention to the work to be done.


The article provides analysis of the current situation and dynamics of spread of the youth extremism in the territory of the Russian Federation and the Urals Federal District. By use of general and specific scientific methods the authors provide criminological characteristics of the most dangerous form of the extremism activities youth extremism. Special attention is paid to the spread of the extremism at the federal and regional levels. The article illustrates the fact that the activities on law-enforcement bodies on youth extremism prevention in the Russian Federation should be pluralistic and it should be limited to punishing and repressive functions of the state, rather it should involve assistance in the interaction of subjects in all of the social institutions. Based upon the study of one of the most vivid aspects of extremist crimes committed by the young people, the article provides general social and special criminological measures, which may form the basis for the successful fight against this unlawful matter.


This thesis deals with the investigation of microstructure and mechanical properties of weld joint of AA5052-H32 and AA6061-T6 aluminum alloys by using MIG welding process. The objective of this thesis is to investigate the effect of parameters to the mechanical properties and microstructure of AA5052-H32 and AA6061-T6. The thesis describes the proper MIG welding process using automatic table in order to investigate the effect on microstructure and mechanical properties of weld joint of AA5052-H32 and AA6061-T6. The aluminum ER5356 was used as filler in this experiment. The studies of mechanical properties that are involved in this thesis consist of toughness, tensile strength of AA5052-H32 and AA6061-T6 weld joint before and after MIG welding process. Four different parameters were used in order to determine the correlation between mechanical properties and microstructure of the weld joint. As a result, it is observed that the current is the parameter which has the highest influence to the UTS and toughness and it is followed by torch angle, speed and lastly weld passes. The optimum parameter for the highest value of UTS and toughness is found; current=90A, torch angle=+15, speed=4mm/s and weld pass=1. The microstructure shows crack sensitivity and porosity which decreases the strength and toughness of weld joint. As for the recommendation, the other properties including hardness, corrosion resistance should be considered in order to optimally select a material for its specific application.


OBJECTIVE: Study of placental morphological changes in intrauterine growth restricted babies. MATERIAL & METHODS: The Study was carried out at Mahatma Gandhi Medical College & Hospital, Jaipur, from January 2011 to January 2012. The placentae were collected from 50 cases of mothers of normal for date babies &50 cases of mothers of IUGR babies. Placental changes studied in both the groups, grossly and histopathologically. RESULTS: The placentae were collected from fifty mothers of normal for date babies & fifty mothers of growth restricted babies. It was observed that mean placental & fetal weights were 385 + 15gm in IUGR as compared to control group 500 + 15 gm Total gross & microscopic pathology in each group were 46% & 94% respectively in IUGR group as compared to 8% each in control groups. Mean fetal weight was low in IUGR group in relation to socioeconomic status, smoking & various disease factors. CONCLUSION: Gross morphology and histopathology of placentae were studied. Gross changes were developmental anomalies, placenta extrachorialis 2% & placenta bipartite 2%. Mean placental diameter in IUGR group was found to be less 15.58 cms as compared to 18.48cms in control group. Tesselation and subchorionic fibrosis was present in 70% & 76% in IUGR group which was found to be less as compared to 90% & 94%in control group1.Calcification, infarction and retroplacental haematoma were present in 54%, 56% & 26% in IUGR which was found more in comparison to 24% &12%in control group. It was concluded


BACKGROUNDAIM: To test the feasibility to use leukemic cell lines in the screening process for anˉticancerous drugs. MATERIAL AND METHODS: Human leukemic cell lines HL-60and K562were tested for their sensitivity to three known anticancerous drugs(Ara-c,DNR,Hom)and a new one(MTB).The drug sensitivity was assessed by four methods(survival cell count, 3 H-TdR incorporation, 3 H-UR incorporation and clone forming assay)and expressed in ED 50 . RESULTS: The curves of survival cell rate determined by the first three methods showed the sensitivity was well within the range of10 -2 ,approxi-mating to one another,while in the case of cloning method,the sensitivity was as high as10 -7 .Besides,the survival cell rate of K562was higher than that of HL-60. CONCLUSION: To use human leukemic cell lines as the target cell for anticancerous drug screening has the advantages that the laboratory procedures are relatively simple and the results are of better clinical significance.


Objective:To construction of recombinant lentiviral expression vector carrying rat peroxisome proliferator-activated receptor gamma(PPAR-γ)gene,and to obtain the titer of the lentiviral stock for investigating the mechanism of PPAR-γexpression in the activation of HSC cells and hepatic fibrosis.Methods:Rat PPAR-γencoding sequence was amplified,then was ligated with pGC-FU-3FLAG lentivirol vector to construct the lentiviral expression vector named pGC-fu-3flag-PPARG.It was identified by PCR,DNA sequencing and Western blot.Virus packaging cells(293T cells) were co-transfected with lentivirol vector pGC-fu-3flag-PPARG,pHelper 1.0 and Helper 2.0 to construct lentiviral.The titers of recombinant viruses were determined by Real time qPCR.Results:Lentiviral expression vector of rat PPAR-γgene proved by sequencing and Western blot was successfully constructed.The titer of recombinant viruses was 2 × 108TU /ml.Conclusion:Rat PPAR-γ lentiviral expression vector was constructed successfully.


This work studies the synergistic effect of carbon nanofiber (CNF) and sub-micro filamentary nickel nanostrand on the thermal and electrical properties, as well as the electro-active shape memory behavior, of a shape memory polymer (SMP) nanocomposite. The combination of electrical CNF and electromagnetic nickel nanostrand is used to render insulating thermo-responsive SMPs conductive. Subsequently, the shape memory behavior of the SMP can be activated by the electrical resistive heating. It is shown that sub-micro filamentary nickel-coated nanostrands significantly improved the electrical conductivity to facilitate the actuation of the SMP nanocomposite despite the low nanostrand volume content and low electrical voltage. Also the CNFs are blended with the SMP resin to facilitate the dispersion of nanostrands and improve the thermal conductivity to accelerate the electro- and thermo-active responses.


In the Chinese revolutionary practice,Chinese Marxists represented by Mao Zedong enriched and developed the essential idea of the historical materialism of liberating and developing productivity. This paper emphatically discusses the four aspects of Mao Zedong's viewpoints to liberate and develop productivity during the periods of new democratie revolution and socialist construction, and we hold that it is the important theory of Mao Zedong Thought to liberate and develop productivity.