The Third Conference on Retroviruses and Opportunistic Infections discussed, in depth, a number of promising drug therapies on the horizon for HIV treatment. A new paradigm in treatment is to administer combinations of drugs in doses that are high enough to lower viral load counts for as long as feasible. Ideally, this treatment will retard HIV replication and delay the development of mutations which lead to drug resistance. Combinations of some of the new protease inhibitors with nucleoside analogs caused thousandfold drops in viral load. However, many of these drugs, especially when used in combination, cause intolerable side effects, so patients sometimes discontinue treatment or use the drugs erratically. The Food and Drug Administration (FDA) is expected to approve indinavir, ritonavir, and serostim at its Antiviral Advisory Committee meeting, and approval is expected in the next few months for delavirdine and nevirapine. Viral load assays continue to be promoted as a means of measuring antiviral activity and shortening trials, and will be used in measuring the effectiveness of potent combination therapies.


palate, rather more marked on the left side, so that the palate moves upward and slightly to the left. A similar movement is present in the oro-pharyngeal muscles, the vocal cords and aryepiglottic folds; it is bilateral and synchronous with the facial and palatal movements. On voluntary movements of the affected muscles the involuntary movements are damped down in amplitude. Abduction of the vocal cords is executed well. There is a slight increase of tone in left arm and leg. All movements are weaker in left arm and leg compared with right. Fine manipulative movements impossible in left hand and there is a failing away of left outstretched arm. Finger-nose and finger-finger tests show a cerebellar type of dysfunction in the left arm; similar but milder condition is present in left leg. All tendon-jerks are brisk. Left arm greater than right arm. Abdominal jerks present. Double flexor plantar response. No sensory loss. Gait.-Cannot walk unaided. Tendency to fall to left with gross unsteadiness. Patient complains of his breathing-feels " short of breath," especially at certain times, when breath " catches." There is an objective noisiness and irregular irregularity of rhythm and amplitude of the respirations. X-ray (screening). Diaphragm.-Both cupolae show a tremor-like movement of about the same frequency as the palatal tremor. Marked salivation. Some difficulty in swallowing. Definite tendency to spontaneous laughter and crying. Heart.-Enlarged slightly. Apical systolic murmur. Blood-pressure.-Systolic 265. Diastolic 160. Urine.-Trace of albumin. Blood Wassermann.-Positive. Cerebrospinal fluid. -Protein slightly increased. Wassermann negative.


Borrowing from concepts of socio-environmental epidemiology and psychology, we conceived self-rated health as a function of multiple physical and psychosocial stressors and resources at the residential neighbourhood and individual level. In this model of multiple stressors, objective exposure to road traffic noise was specified as a physical stressor whose effect on health may be mediated and modified by residents' subjective response to noise (serious noise annoyance). Self-reported hearing disability, recreational coping in green areas and residential neighbourhood satisfaction were examined as additional psychosocial stressors or resources, independently of socio-demographic and -economic factors. Results from our empirical analysis based on two studies and multivariable logistic regressions might support the idea that environmental planning should overcome sectoral boundaries and adopt an integrative approach including objective exposures, residents' subjective responses, and perceived resources.


We read with interest the letter of Burzotta et al. regarding our article [1] describing the carina modification T stenting (CMT) as a provisional bifurcation stenting technique. We fail to see the confusion exuding from the author's letter regarding our presented data and its clinical significance. First, our 156 patients presented were enrolled from January 2004 until March 2006, with a long-term follow-up of up to 48 months. We coined the technique of CMT as we felt that the formation of a neocarina by this T-stenting technique is integral to the success of this procedure. This is clearly shown at bench testing and IVUS studies [1]. CMT was presented as a technique and a procedural nomenclature in several international interventional meetings (including EuroPCR, CardioALEX, Complications Course, and GIM) well before TAP [2] was published in 2007. We did acknowledge the work by Burzotta et al. [2] as it supports and sheds more evidence on this bifurcational stenting technique. It would be interesting to call the elegant work of Burzotta et al. as ''CMT in the hands of other operators,'' as the technique, whatever name you chose to call it, has a high procedural success rate and good shortand long-term outcomes. Second, our article was not meant to compare single versus double stenting and the comparative outcomes in bifurcations. Burzotta's final paragraph dwells on this point, resulting, in his opinion, to incorrect scientific perspectives that will confuse the readers. It is clear from our publication that CMT is a provisional bifurcation stenting technique that can be utilized after main vessel (MV) stenting. If the side branch (SB) vessel is then deemed to require stenting, CMT can be used. If not, the procedure can be terminated with a single MV stent. Our data presented those patients where the operator decided on stenting the SB, utilizing CMT. Lastly, in the European Bifurcation Club classification of lesions and their treatments published in 2008 [3], it is evident that a lot of effort was undertaken to compare techniques in homogenous lesion groups. It was clear that several bifurcation stenting techniques underwent nomenclature changes, such as reverse crush to internal crush. TAP in the article was also named ''exaggerated Y,'' a potential reflection of the change in the carina of the bifurcation deemed significant. We would like to end with a quotation from Shakespeare's ''Romeo and Juliet'': ''What's in a name? That which we call a rose By any other name would smell as sweet.''


Nothing can reflect a reality as close as that lived from the personal experience of the researcher. Be part of the indigenous population of the ethnic karanki, a resident of the parish the Hope of the canton Ibarra, facilitated a holistic understanding of the problem related to lack of implementation of inclusive intercultural strategies in the learning process of the subject in Language and Literature with students in seventh grade general education basic educational unit "Vasco Nunez de Balboa" in the community of the Abra.
For the child population is indigenous to say the least, very complicated acquire knowledge in a maternal language. This is what happens traditionally in the public and private schools established in the marginal rural areas with high indigenous population density, with Spanish speaking teachers and with little training in the implementation of inclusive teaching practices. The research considers important to work with intercultural strategies in the development of the learning process, on the basis of the teaching materials, important resources for the achievement of the objectives, because they have the advantage of owning three basic characteristics that facilitate the rapprochement of the student toward the learning contents: the display through images, the perception of the messages, using the sequence of signals and participation, exploration and manipulation, through the actions that must be run to build their own knowledge. If so, joins the use of the native language of students as a strategy for understanding inclusive that addresses their individual characteristics, then, this project will contribute significantly to the achievement of knowledge with good results.


Mathematization of research is one of the most effective methods of virtual substantiation of foodstuff recipe and technology. This approach allows creating a product that meets consumer's individual needs, i.e. personalized foodstuff (ethnicity, cultural preferences, regional and environmental characteristics, lifestyle), and at the same time reducing the time and cost of decision-making. The article discusses the hypothesis that the "digital twin" of a food product is a virtual model of the product, namely its mathematical model (simulation model). A simulation model is a logical and mathematical description of a food product that is used to conduct a computerized experiment in order to design desired characteristics and properties. The "digital twin" combines all variety of factors from chemical composition, functional and technological properties to organoleptic indicators. The application of the "digital twin" model of the foodstuff will allow: (1) reacting quickly to changes in the composition, properties and types of raw ingredients, (2) adjusting the product recipe in response to changes in consumer preferences, (3) designing products with a given chemical composition, nutritional value and functional orientation, (4) creating functional, specialized products taking into account the metabolism of nutrients (ethnicity, cultural preferences, health status and clinical factors). Products adapted to the needs of small categories of people will help reducing the risks for those who already have diseases, and will meet the needs of those who would like to make their diet more appropriate to individual needs. The proposed approach to creating a model of the "digital twin" of the foodstuff includes several stages. The first stage involves optimization of the nutritional and biological value of the designed product. The second stage is related to designing the food product's structural forms. But even if the recipe of a food product is optimally selected in the first stage, it does not guarantee its transformation during processing into a stable system with the required structural, mechanical, functional and technological parameters. Evaluation of the developed food product's efficiency is possible only by analysing numerous and various parameters and indicators. It is convenient to generalize (convolute) many parameters and indicators into a single quantitative dimensionless indicator. To assess the quality and adequacy of the food product, it is suggested to use an integral indicator in the form of additive convolution – the 'functional' of the food product quality.


The aim of this survey was to assess midwives' knowledge of Down's Syndrome screening and their confidence in counselling women about the screening test. A questionnaire was sent to 280 clinical midwives working in a large trust in the north of England in July 1999. The overall response rate was 58% (162/279). Poor knowledge was found in 41 % of responders. Only 39% (42/144) of midwives reported they were confident in counselling women about the screening test. These results indicate that for a significant proportion of midwives inadequate knowledge of Down's Syndrome screening and low confidence in counselling women about the tests are perceived problems in their work.


Cultural Health Beliefs and Influenza Vaccination Among Caribbean–Born Students by Dona S. Walcott MPH, Florida International University, 1997 BA, University of South Florida, 1990 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Psychology Walden University May 2019 Abstract This purpose of this quantitative study was to examine health beliefs among Caribbeanborn university students regarding acceptance or rejection of influenza vaccination among populations at institutions of higher education. In addition, acculturation was addressed as a factor affecting cultural health beliefs. A survey was completed by 98 students enrolled at Florida International University during the spring 2018 semester. Linear regression was used to analyze whether cultural health beliefs and acculturation were predictive of beliefs about influenza vaccination and beliefs about perceived barriers to influenza vaccination. The study findings showed cultural health beliefs of the students were statistically significant predictors of their beliefs about influenza vaccination and perceived barriers to influenza vaccination. Also, the levels of acculturation were a statistically significant predictor of students' cultural health beliefs and beliefs about perceived barriers to influenza vaccination. After 5+ years of acculturation in the United States, the students surveyed still held cultural beliefs and perceived barriers to influenza vaccination that contributed to their lack of acceptance of the vaccination. The information gained from this study gives credence to the need for designing health interventions and health messages on influenza vaccination that are culture specific for a college-age population if influenza vaccination acceptance is to be promoted.This purpose of this quantitative study was to examine health beliefs among Caribbeanborn university students regarding acceptance or rejection of influenza vaccination among populations at institutions of higher education. In addition, acculturation was addressed as a factor affecting cultural health beliefs. A survey was completed by 98 students enrolled at Florida International University during the spring 2018 semester. Linear regression was used to analyze whether cultural health beliefs and acculturation were predictive of beliefs about influenza vaccination and beliefs about perceived barriers to influenza vaccination. The study findings showed cultural health beliefs of the students were statistically significant predictors of their beliefs about influenza vaccination and perceived barriers to influenza vaccination. Also, the levels of acculturation were a statistically significant predictor of students' cultural health beliefs and beliefs about perceived barriers to influenza vaccination. After 5+ years of acculturation in the United States, the students surveyed still held cultural beliefs and perceived barriers to influenza vaccination that contributed to their lack of acceptance of the vaccination. The information gained from this study gives credence to the need for designing health interventions and health messages on influenza vaccination that are culture specific for a college-age population if influenza vaccination acceptance is to be promoted. Cultural Health Beliefs and Influenza Vaccination Among Caribbean–Born University Students by Dona S. Walcott MPH, Florida International University, 1997 BA, University of South Florida, 1990 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Psychology Walden University February 2019 Dedication I dedicate my dissertation to my parents for instilling in me the value of an education and the persistence to pursue one, with special dedication to my dad, Elmer Walcott, who has been my biggest champion. I dedicate my dissertation to my children, Khemaron and Breana for understanding why their mom spent so many nights and years of their lives studying, but they never stopped supporting me. Finally, I dedicate my dissertation to myself for investing my mind, heart and soul for 12 long years. Acknowledgments To my family, my children, a few friends, and my loved one for their neverending support throughout my dissertation journey. Thank you. To my Chairperson, Dr. Jessica Tischner, for being that one guiding light that has successfully mentored me through this process. Thank you to her is not enough. Thank you to my second committee member, Dr. William Tetu and my URR for their effective reviews. To my assistant, staff members, colleagues , FIU ISSS Department and others, too numerous to mention, who have assisted me along the way. Thank you all.


Subtracting the Strutinsky shell corrections from the selfconsistent energies obtained within the Relativistic Mean Field Theory (RMFT) we have got estimates for the macroscopic part of the binding energies of 142 spherical even-even nuclei. By minimizing their root-mean-square deviations from the values obtained with the Lublin-Srasbourg Drop (LSD) model with respect to the nine RMFT parameters we have found the optimal set (NL4). The new parameters reproduce also the radii of these nuclei with an accuracy comparable to that obtained with the NL1 and NL3 sets.


The North Bridge is situated in the centre of Edinburgh and spans Waverley Station and Market Street. The present bridge was constructed in 1894-96 to replace the previous masonry arch structure. T...


Metamizole (dipyrone) is an analgesic that has been the focus of considerable controversy regarding its safety. Because of potentially life‐threatening blood disorders such as agranulocytosis, it has been withdrawn in many countries but not in Germany, where prescribing even increased over recent years. We aimed to evaluate prescribing of metamizole in Germany with respect to age, sex and regional variations.


With the method of infinitesimal element,We hare worked out an integrating formular which can be used to calculate the area of the curved surface of revolution generated from a circular motion of a line on a planar currilinear.


This dynamic document contains the patient-level data as well as computer source codes for the reproduction of tables and figures presented in the manuscript "The Impact of Prepartum Factor XIII Activity on Postpartum Blood Loss" (Haslinger et al., 2020). This document is described as supplementary in the main publication, unfortunately, the publisher was unable to provide access to this document through their system. The source file blood loss report.Rnw can be processed in the R system via library("knitr") knit("blood_loss_report.Rnw")


Achieving highly active and stable oxygen reduction reaction (ORR) performance at low platinum-group-metal (PGM) loadings remains one of the grand challenges in the proton-exchange membrane fuel cells (PEMFCs) community. Currently, state-of-the-art electrocatalysts are high-surface-area-carbon-supported nanoalloys of platinum (Pt) with different transition metals M (M = Cu, Ni, Fe, Co, etc.). Nevertheless, despite years of focused research, the established structure-property relationships are not able to explain and predict the electrochemical performance and behaviour of the real nanoparticulate systems. Unlike the perfect core-shell systems, usually used to model the observed behaviour of the electrocatalysts by the community, nanoparticles in real nanocatalysts exhibit much greater local atomic-scale structural complexity. Structure-property relationships addressing averaged material properties, such as the actual ORR activity and metal degradation (e.g. dissolution) behaviour, are at risk of oversimplifying the underlying phenomena when they rely on top-down characterization techniques and attribute averaged affects to idealized nanoparticle structures. In this work, we reveal the complexity of commercially available Pt/C and Pt-M/C electrocatalysts and discuss the relevance of understanding their stability behaviour in fuel cell systems. We expose the limitations of the established top-down characterization methodologies for studying degradation and provide a conceptual approach that offers a new dimension and transcends the limits of conventional structure-stability studies. We outline a bottom-up approach where atomically resolved properties, structural changes and strain analysis are recorded as well as analysed in great detail on an individual nanoparticle. While fundamental, this approach addresses the complexity of practical electrocatalysts and enables studying their stability when exposed to realistic electrochemical conditions (i.e. high current density). This methodology, in our opinion, offers the new level of understanding structure-stability relationships of practically viable nanoparticulate systems.


The up-flow biological aerated filter with porcelain media was adopted to treat domestic sewage.The influence of hydraulic retention time,air/water ratio and influent organic concentration on the performance of the biological aerated filter was studied.The results show that under the conditions of temperature 11.5 to 32.9 ℃,air/water ratio 3 ∶1,influent COD 90.6 to 419.0 mg/L,NH+4-N 7.85 to 47.51 mg/L,TN 16.76 to 58.40 mg/L and SS 80 to 270 mg/L,the relation between COD removal rate and hydraulic retention time is not linear,and the optimal HRT is 10 h.With the decrease of HRT,the removal rate of NH+4-N is reduced,and the removal rate of SS is slightly reduced.When the air/water ratio is 1 ∶1,3 ∶1 and 5 ∶1,the increasing of air/water ratio causes higher removal rates of COD and NH+4-N,but a lower removal rate of TN.When the influent organic concentration is 100 to 400 mg/L,with the increasing of the influent organic concentration,the removal rate of COD increases,but the removal rate of NH+4-N is changed hardly.


.  This article traces the intellectual history of scientific studies of intercessory prayer published in English between 1965 and the present by focusing on the conflict and discussion they prompted in the medical literature. I analyze these debates with attention to how researchers articulate the possibilities and limits medical science has for studying intercessory prayer over time. I delineate three groups of researchers and commentators: those who think intercessory prayer can and should be studied scientifically, those who are more skeptical and articulate the limits of science around this topic, and those who focus primarily on the pragmatic applications of this knowledge. I analyze these contests as examples of what Thomas Gieryn calls "epistemic authority" as medical researchers engage in what he describes as "boundary-work" or "the discursive attribution of selected qualities to scientists, scientific methods, and scientific claims for the purposes of drawing a rhetorical boundary between science and some less authoritative residual non-science." (Gieryn 1999, 4 (Gieryn 1999, 4)).


A switching median filter (SMF) is effective for impulse noise removal while still preserving edges in an input image. This filter firstly detects pixels corrupted by impulse noise and then filters only the noise-corrupted pixels. However the noise detection process does not always work perfectly. Particularly, pixels constituting thin lines in an input image tend to be incorrectly detected as noise-corrupted pixels, and such pixels are filtered despite the needlessness of the filtering. As the result of the filtering, the image might be over-smoothed and be deteriorated throughout the entire image. To cope with this problem, we propose a new impulse noise removal method based on a one-dimensional SMF and a space-filling curve which reflects structural contexts of an input image. The effectiveness of the proposed method is verified by some experiments.


The increasing use of enteral nutrition comes with new challenges, especially when the same device is used simultaneously as a route for drug administration. Therefore we are faced with the need to increase the knowledge about undesirable interactions of all stakeholders involved, in order to avoid the use of inadequate techniques of drug administration through feeding tube. Considering the above, there is an urgent need to develop tools able to analyse the viability of drug delivery through feeding tube. The idea behind this work was the development of computer software based on our theoretical database. This tool would be able to alert health practitioners about an imminent risk of drug-nutrient interaction when using this technique of delivery minimizing risk. This tool could operate as an interface with the electronic prescription program, alerting the prescriber about a possible risk of interaction enabling the choice of a more adequate route of administration or a change to a different drug or formulation.


In this paper, the mechanical characteristic of the vacuum circuit breaker (VCB) is tested by an advanced instrument and analyzed. Some problems with the conventional method to measure the mechanical characteristic are discussed.


This study applies bootstrap panel Granger causality test of to examine the causal relationship between globalization and insurance market activities in large emerging market economies. Economic, social, political and overall globalization indices are considered separately, and 3 alternative measures of globalization (hybrid, de facto and de jure) are also used in each case for our estimations. The empirical results confirm the following; first, empirical outcomes are sensitive to the choice of globalization measure used. Second, cross-sectional dependence and cross-country heterogeneity exist among large emerging market economies. Third, causality varies across large emerging economies with different conditions, and social globalization has the most widespread effect on insurance market activities.


This book documents and analyses the involvement of Norway in the liberation struggle in Southern Africa. Apart from focussing on the formulation of official policies and the extensive cooperation ...


The article is devoted to the transformation of the traditional values of Russian society as a form of information and psychological warfare to establish the geopolitical control.


Hydrocarbon and perfluorinated polymers display distinct thermodynamic partitioning characteristics. These differences enable perfluoropolymers to outperform hydrocarbon polymers for many membrane-...


A tractor drawn Soybean drum planter was designed, fabricated and tested in the DESFABENG Company Limited, Bida, Niger State. The project was undertaken due to the fact that most of the imported planters usually have maintenance and repair problems in addition to high costs of procurement that are not affordable to an average farmer. The major components of the developed planter are three drums with predetermined hole sizes at the exterior ends, a central rectangular shaft, spring soil openers, roller soil coverers, tractor hitching points, two wheels and power transmission mechanism and frame. All these components were fabricated with locally available materials. Using three test speeds, the planter was preliminarily assessed for seed rate, soil opening, covering and germination efficiencies. Results obtained indicate that desirable seed rate values of 47.7 and 61.2 kg/ha were observed for tractor/implement speeds of 20 and 16 km/hr, respectively. The highest germination efficiency of the planter was 81.3% at tractor/implement speed of 16 km/hr with corresponding soil opening efficiency of 94%.


Effects of Lovelock gravity on the Joule–Thomson expansion are probed from various perspectives. The well-known Joule–Thomson coefficient is derived with both the explicit expression and intuitive image presented. Moreover, the inversion curves showing the relation between the inversion temperature and the inversion pressure are studied. It is shown that for given inversion pressure, the inversion temperature of the case ( is the Lovelock parameter) is much lower than that of the case . And the inversion temperature tends to decrease with , in contrast to the effect of the electric charge. It is also shown that the ratio between the minimum inversion temperature and the critical temperature decreases with for . Furthermore, the isenthalpic curves are investigated with rich physics revealed. The intersection point between the isenthalpic curve and the inversion curve is exactly the inversion point discriminating the heating process from cooling process. It is shown that both the inversion temperature and the inversion pressure for are much lower for the same given mass of the black hole, showing the effect of Lovelock gravity. Last but not the least, we discuss the uncharged Lovelock AdS black holes. It is shown that the Joule–Thomson coefficient is always positive, suggesting the expansion is always in the regime of cooling process. And no inversion temperature exists, in contrast to the case . Isenthalpic curves are also quite different since the temperature increases monotonically with the pressure when the mass is specified.


To evaluate the efficacy and safety of combined use of tranexamic acid (TXA) and dexamethasone (DEX) for anti‐inflammatory and clinical outcomes after total hip arthroplasty (THA).


A Mt.Nan coal mine changing room boiler room SZL4.0-1.27 steam boiler,changes the gas-fired boiler by the coal-fired boiler,takes boiler's main fuel with the mine shaft gas gas,like this not only saved the coal,moreover reduced the massive cinders which the mist and dust withdrawal and the coal-burning produce to the environment pollution,also guaranteed the unnecessary gas gas blows off to the atmospheric pollution,after the transformation,gas-fired boiler's application both saves the energy,and has brought the huge economic efficiency.


The purpose is to study the mucosa from its luminal surface to the lamina muscularis mucosae in the first two parts of the third compartement of camel's stomach. The material originates from six adult one‐humped camels, ageing between 2 1/2 and 10 years, for ordinary histology and histochemistry.


Artifact play a major role in software development. An artifact in software development is an actual by-product in which the works are documented and stored in a repository so it can be retrieved upon demand. Artifacts in software engineering involves specific development methods or processes. To make the software development outright, the collection of information is organized as artifact set. Build involves in converting source code into software artifact. The presence of build helps to provide tangible and observable results. Document clustering involves in organizing and managing texts in structured format. Document clustering provides feasible results increasing the accuracy and saves time when compared to manual text classification.


Based on normative and doctrinal sources, the author examines the historical development of procedural coercion measures in the criminal proceedings of the German-speaking states on the example of classical legal monuments and modern codes of the 19th-20th centuries. Initially, the system of coercive measures in these legal orders looked rather primitive and archaic (for example, during the period of the Saxon Mirror of 1230), but over time it began to become more complicated, a general part and a special part separated in it. In the states under consideration, there is a tendency to expand the list of measures of procedural coercion, to establish additional guarantees of the rights and freedoms of the person to whom they apply. An analysis of the Carolina of 1532 shows that the legislator sought to clearly regulate the grounds and conditions for choosing a measure of coercion in the form of detention for the accused, since this form most seriously interferes with the sphere of their personal rights. The Theresiana of 1769 for the first time provided for house arrest, which was used along with imprisonment in a fortress and in prison. In the transition from an inquisitorial criminal procedure to a mixed one, coercive measures become the object of judicial control. The legislator seeks to find a balance between the interests of the accused and the interests of justice in criminal cases. This article may be useful to anyone interested in criminal proceedings and in the history of the state and law of foreign countries.


A probabilistic hazard analysis of a tsunami generated by a subaqueous volcanic explosion was performed for Taal Lake in the Philippines. The Taal volcano at Taal Lake is an active volcano on Luzon Island in the Philippines, and its eruption would potentially generate tsunamis in the lake. This study aimed to analyze a probabilistic tsunami hazard of inundated buildings for tsunami mitigation in future scenarios. To determine the probabilistic tsunami hazard, different explosion diameters were used to generate tsunamis of different magnitudes in the TUNAMI-N2 model. The initial water level in the tsunami model was estimated based on the explosion energy. The tsunami-induced inundation from the TUNAMI-N2 model was overlaid on the distribution of buildings. The tsunami hazard analysis of inundated buildings was performed by using the maximum inundation depth in each explosion case. These products were used to calculate the probability of the inundated building given the occurrence of a subaqueous explosion. The results from this study can be used for future tsunami mitigation if a tsunami is generated by a subaqueous volcanic explosion.


Inflammatory bowel disease is a chronic inflammatory condition for which patients may require care on a more urgent basis. Response times can be delayed when clinics are inundated with calls or when providers are not available for immediate patient care. We developed and tested an algorithm to empower nurses to effectively triage phone calls and improve access.

 We created an algorithm for nurses handling phone calls and electronic messages to a tertiary care IBD clinic. Calls were divided into four categories: Needs Immediate Response, Disease Flare, Routine and Other. IBD nurses triaged calls to facilitate urgent visits with a nurse practitioner (NP) when deemed appropriate, bypassing physician review or response. We compared the time from call-to-visit during the 3 months before and 3 months after implementation of the algorithm. We also assessed clinical outcomes of these urgently scheduled visits including visit type (in-person or virtual), and whether there was a change in dose or type of therapy, new prescription of steroids, or emergency room referral. We used the Mann Whitney U Test to assess for pre-post changes.

 We randomly assessed 60 visits per month in the 3 months before and 3 months after the algorithm was implemented (June 1, 2022), for a total of 360 visits. The median time from call-to-visit improved from 5 days during the 3 months prior to the algorithm implementation to 3.5 days during the 3 months after algorithm implementation (p=0.016). There was no significant change in visit type pre- and post-intervention. Overall clinical interventions during these visits included therapy change (36%), a new prescription of corticosteroids (9%), new diagnostic testing ordered (67%) and ER referral (1%); these did not significantly differ in the pre- and post-intervention periods.

 Utilization of a phone call triage algorithm by nurses can help improve the time from call-to-visit without involvement of a physician. Urgently scheduled NP visits result in important clinical interventions including changes to therapy and diagnostic testing. Implementation of nurse-led triage algorithms can improve access to care in a tertiary IBD clinic.


In automatic generation control (AGC), the determination of frequency deviation coefficient under the mode of tie line bias control (TBC) plays an important role in the control system stability and frequency recovery. Based on the analysis of the actual operation of AGC, this paper presents a method to determine the frequency deviation coefficient. Firstly, considering the limitation of current automation level, a frequency deviation coefficient model for all-day multiperiod under different operating modes is established according to the frequency response characteristic of power system. Then, in order to meet the requirements for frequency recovery in the actual power grid, a strategy to modify the frequency deviation coefficient according to the frequency deviation is proposed. Finally, due to the continuous improvement of the penetration rate of new energy in the power system, this paper also considered the influence of wind power in the load frequency control system (LFC) model. The effectiveness of the method is verified by the simulation results of two areas interconnected power system.


Sirs, The possible role of aged gametes in the causation of malformed embryos, discussed by Jongbloet (1984), has been studied by others including Blandau & Young (1939) and Nishimura (1975). However, its importance relative to the role of hereditary (as well as several environmental influences) is not clear and requires further study. With reference to the prolonged birth intervals prior to the birth of cleft offspring which we have observed (Dronamraju & Bixler 1984a), Jongbloet's discussion does not take into account the problem of identifying truly sporadic cases. In a recent discussion of the origin of sporadic cases (Dronamraju & Bixler 1984b), we emphasized that although the classification of clefts into sporadic and familial groups may be useful in certain analytical contexts (Melnick et al. 1980, Shields et al. 1981), this classification is potentially erroneous although the exact number in error is impossible to define at present. This is so because what appears to be a sporadic case at birth may be the only live-born cleft remaining of several cleft cases conceived. As shown by Nishimura (1 979, prenatal selection eliminates a substantial fraction of malformed conceptuses through embryonic and fetal mortality. Thus, the number of truly sporadic cases is smaller than the number of sporadic cases observed at birth. In addition, we do not agree with certain other statements in Jongbloet's discussion. It is well known that a positive family history can result from a number of causes (although the most likely one may be genetic etiology), and that a sporadic occurrence is not necessarily indicative of a "non-Mendelian mechanism". When the mode of inheritance is not known, sporadic cases may turn out to be as genetic in origin as any others. Yet, Jongbloet appears to equate familial with a Mendelian genetic mechanism and sporadic with a non-Mendelian mechanism! Such statements without qualification concerning the complexity of the etiological mechanisms are misleading. With reference to the possible association of maternal age effect with sporadic probands, the extensive French data of Bonaiti et al. (1982) do not support Jongbloet's assertion. On the contrary, Bonaiti et al. (1982) found that paternal age is increased in familial cases of CP (a probable birth order effect), and no paternal or maternal effect was noted for sporadic groups of either CP or CLP. In our studies of Indiana cleft data, an increase of mean parental ages was found for sporadic cases in the CLP group only but not in CP (Dronamraju & Bixler 1984b). Thus, the evidence in favor of Jongbloet's hypothesis is inconsistent at best.


By fabricating micro-scale Spiral Phase Plates within the aperture of a Vertical-Cavity Surface-Emitting Laser, a beam carrying specific OAM modes and their superposition states can be directly emitted with high efficiency and high beam quality.


Three months ago, a massive earthquake hit the disputed region of Kashmir in northern Pakistan. Now that the initial images have disappeared from the media, what hope is left in their wake?


Urine samples have been analyzed for silicon using graphite furnace atomic absorption spectrometry. The samples were simply diluted(1+349) with distilled water and introduced into pyrocoated graphite tube together with nickel modifier. Atomic absorption signal was recorded at 251.6 nm wavelength. Under these conditions, the detection limits of silicon are less than 0.7 mg/ml for urine sample. The quantitative performance of the proposed technique applied to urine samples was compared with that obtained from inductively coupled plasma emission spectrometry.


The objective of this study is to examine the effect of adoption intensity of GM crops on off‐farm labor supply by farm households. Using ARMS data in 2004, 2005 and 2006, we estimate a two stage simultaneous Tobit model and find that adoption intensity of GM crops has a negative impact on off‐farm labor supply by operators and a positive impact on off‐farm labor supply by spouse. This may be due to the comparative advantage of operators and spouses. Our results find that GM crops adoption has different but significant implications on off‐farm labor supply by operators and spouses and underscores the importance of understanding farm households' decisions to explain behaviors of farm businesses in the United States.


A comprehensive research composed of theory analysis,physical simulation and field measurements was conducted to analyse the impact effect caused by fracture of the thick and hard roof group structure to obtain the main factors influencing impulsion pressure,main roof weighting characteristics and rupture characteristics of the roof group structure.The research shows that impact load caused by fracture of the hard layered roof group structure presents a significant fluctuation over a short period,and the roof weighting on the workface is affected by combined effects resulted from layered roofs group fracture.Impulsion pressure strength is associated to the roof thickness and rock properties.For the similar roof strata,the impact effects are more severe if the roof is thicker,but the thick caving roof will buffer the impact from the upper overburden strata.A field test has been conducted in Datong area which is mining under hard roof group structure.,Roof weighting characteristics on the workface was obtained according to the test.It shows that the fracture and unstability of the layered roof arerandom,however both monolayer and roof group have stable probability to break down in terms of entire mining process.


This study investigates how broker relationships emerge to bridge otherwise disconnected market actors. I specify conditions under which sellers willingly pay brokerage fees and accept to be broker...


As modern transportation is developing rapidly,the relationship between transportation and energy,people and vehicle is becoming increasingly tense,and ecological environment is degraded.Therefore,it is necessary to think over the situation,the human existence and its meaning through the traffic.Through profound rethinking of value,it is easy to recognize the relationship among traffic,human,society and nature,explore the culture of green transportation,and put forward the sustainable development.To do this,it's necessay to fufil the three-demensional turns.First,the development of transportation call for attention not only to human and society but also to nature and environment.In the value,the emphasis of the traditional emphasis on speed and benefit should be shifted to the ecological balance.Second,transportation should be studied in panoramic sight,analyzed its aim,function,condition and other factors,and one-way thinking should be transformed into multi-way thinking.Third,it is necessary to build proper atmosphere to accelerate the change of green transportation system,clear out its block,gradually form a complete green transportation system.


According to the spatial registration hypothesis, the representation of stimulus location is automatically encoded during perception and it can interact with a more abstract linguistic representation. We tested this hypothesis in two experiments, using the semantic judgements of words. In the first experiment, words for animals that either fly or do not fly were presented either in the upper or lower part of a display relative to the fixation point. Reaction times showed significant interaction between the spatial position and the word type. The words for flying animals were judged faster when they were presented in the upper part while the words for non-flying animals were processed faster in the lower part of the display. In the second experiment we extended the stimulus set to words denoting non-living things which are associated with either upper or lower spatial position. Again, reaction times showed significant interaction between the actual spatial position where the words were presented, and their implicit association with upper or lower spatial position. The results provide support for the claim that spatial representation has an active role in lexical processing.


The present research investigates the removal of arsenic (As) from aqueous solutions using micellarenhanced ultrafiltration (MEUF) by utilizing two different surfactants: benzethonium chloride and dodecyl pyridinium chloride (BCl and DPCl). The impact of the operating variables and maximum removal efficiency were found under different conditions for BCl and DPCl surfactants. The maximum As rejection efficiency for MEUF with BCl and DPCl surfactants is 92.8% and 84.1%, respectively. In addition to this, a statistics-based experimental design with response surface methodology was used for the purpose of examining the impact of operating conditions, including initial pH, initial As concentration (ppb), and surfactant concentration (BCl, mM) in As-removal from aqueous solutions. In the analysis of the experimental data, a second-order polynomial model that was validated by statistical analysis for the BCl surfactant was used. On the basis of the response model created, the removal of As ions was acquired at optimum operating parameters, including the initial As concentration of 150 ppb, surfactant concentration of 5 mM and pH 10 for the BCl surfactant with 92.8% As-removal efficiency. doi: 10.2166/ws.2019.188 om http://iwaponline.com/ws/article-pdf/20/2/574/765248/ws020020574.pdf er 2021 Oznur Begum Gokcek (corresponding author) Faculty of Engineering, Department of Environmental Engineering, Nigde Omer Halisdemir University, 51240 Nigde, Turkey E-mail: email@example.com Nigmet Uzal Faculty of Engineering, Department of Civil Engineering, Abdullah Gul University, 38380 Kayseri, Turkey


With the development of electronic technology,the power supply of high frequency switch has been put in various areas of electronic and electrical apparatus.Recently,the control of power supply of high frequency switch has been developed towards the "high refined and cuspidate" direction.Although the parts of apparatus have small volume and refined precision,the Electro Magnetic Interference(EMI) and radiation are much stronger than before.So in order to make it work normally in prospective electro circumstance,without efficiency reduce and malfunction,and without electromagnetic interfere to anything in electro circumstance,we have to make an Electro Magnetic Compatibility(EMC) for the power supply of high frequency switch.This article mainly discusses some approaches and compatible measures of electromagnetic interfere in power supply of high frequency switch.


We propose a M-quantile regression model for the analysis of multivariate, continuous, longitudinal data. M-quantile regression represents an appealing alternative to standard regression models, as it combines the robustness of quantile and the efficiency of expectile regression, providing a complete picture of the response variable distribution. Discrete, individual-specific, random parameters are used to account for both dependence within the same response recorded at different times and association between different responses observed on the same sample unit at a given time. A suitable parametrisation is also introduced in the linear predictor to account for possible dependence between the individual specific random parameters and the vector of observed covariates, that is to account for endogeneity of some covariates. An extended EM algorithm is proposed to derive model parameter estimates under a maximum likelihood approach. The model is applied to the analysis of the strengths and difficulties questionnaire scores from the Millennium Cohort Study in the UK.


The reversible addition–fragmentation chain transfer (RAFT) polymerization of acrylic acid (AA) in water was studied in detail at different pHs using 4-cyano-4-thiothiopropylsulfanyl pentanoic acid (CTPPA) as a control agent and 4,4′-azobis(4-cyanopentanoic acid) (ACPA) as an initiator. Well-defined hydrophilic macromolecular RAFT agents (PAA-CTPPA) were obtained and further used directly in water for the polymerization of styrene. The corresponding polymerization-induced self-assembly (PISA) process was evaluated at different pHs and it was shown that working in acidic conditions (pH = 2.5) led to well-defined amphiphilic block copolymer particles (Đ < 1.4) of small size (below 50 nm). When the pH increased, the control over the growth of the polystyrene (PS) block was gradually lost. Chain extension experiments of PAA-CTPPA with N-acryloylmorpholine (NAM), a hydrosoluble and non-pH sensitive monomer, performed at different pHs showed that the very first addition–fragmentation steps that occurred in wate...


Through practice and test,technical specification and field management technique of good quality and high production in soybean's planted were put forward.


Replacing conventional solvents by ionic liquids is often suggested as a possible route to greener industrial processes. However, ionic liquids are typically petroleum-derived. This critical perspective discusses the syntheses, applications and limitations of biobased ionic liquids synthesized from amino acids, carbohydrates, lignin and other renewable sources. The practical aspects of applying such ionic liquids in lignocellulose processing, as a reaction solvent, organocatalyst or as metal extraction medium are highlighted.


A novel microstrip active bandpass filter with harmonic suppression is investigated. The structure is composed of multiple coupled passive and active rings. A microstrip active bandpass filter at 1.37 GHz with a gain of 6 dB, return loss >15 dB and a harmonic suppression ratio over 25 dB has been implemented.


AbstractThis paper numerically models the behavior of double-shear, single-bolted joints in wood-steel structures when subjected to very large deformations and compares results with test informatio...


While studies on hydrological extremes, and floods in particular, usually take a retrospective approach, the German Helmholtz initiative MOSES (Modular Observation Solutions for Earth Systems) aims at understanding extreme events by observing the flood generation processes directly where they occur: in-situ and during the event. As part of this framework, we present a new concept of monitoring regional water storage changes by combining event-based ad-hoc field campaigns with continuous monitoring, using terrestrial gravimetry for total water storage variations and cosmic ray neutron sensing for near-surface soil moisture variations. In this concept, a key role is taken by a continuously monitoring gravimeter station: the gPhone solar cube. This station is energy self-sufficient and easily deployable at any remote location, hosting a gPhoneX, a full weather station, a GNSS antenna and receiver and a cosmic ray neutron probe. The purpose of this station is i) to provide data describing the longer term hydrological dynamics of the study area including the pre-event conditions and ii) to serve as the reference station for the gravity field campaigns during the event. These field campaigns, triggered by forecasts of extreme weather events, are carried out at least prior and after the event on a network of points across the study site. The locations are chosen with respect to the size of the area of interest, topography and travel times between the points. Measurements at each point include relative gravity with two CG-6 instruments, absolute gravity with a Muquans atom quantum gravimeter (AQG) and near-surface soil moisture using three cosmic ray neutron probes in a mobile rover setup. The same routine is strictly repeated at each point to assure uttermost comparability of the measurements. The AQG is also used to calibrate the permanently installed gPhoneX and, thus, to use the gravity reference station for correcting the high instrumental drift of the CG6 gravimeters. The monitoring concept is expected to be transferable to all areas where a similar interest in water storage dynamics at event time scales is strived for.


Utilization of semiconductor integrated circuits in modern microwave systems has considerably increased in recent times. The trend is the result of the significant technological advances in silicon and silicon-germanium technologies that enabled production of commercially attractive circuits having performance in line with the performance of the traditional monolithic microwave integrated circuits (MMICs) made from GaAs or similar III-V compounds.


Important datacenter applications generate extremely bursty traffic patterns and demand low latency tails as well as high throughput. Datacenter networks employ shallow-buffered, shared-memory switches to cut cost and to cope up with ever-increasing link speeds. End-to-end congestion control cannot react in time to handle bursty, short flows that dominate datacenter traffic and they incur buffer overflows, which cause long latency tails and degrade throughput. Therefore, there is a need for agile, switch-local mechanisms that quickly sense congestion and provision enough buffer space dynamically to avoid costly buffer overflows. We propose Smartbuf, an online learning algorithm that accurately predicts buffer requirement of each switch port before the onset of congestion. Our key novelty lies in fingerprinting bursts based on the gradient of queue length and using this information to provision just enough buffer space. Our preliminary evaluations show that our algorithm can predict buffer demands accurately within an average error margin of 6% and achieve an improvement in the 99th percentile latency by a factor of 8x at high loads, while providing good fairness among ports.


207 Background: The incidence of colorectal cancer (CRC) among individuals younger than age 50 (young-onset CRC; YOCRC) has increased, yet the etiology and molecular mechanisms underlying this alarming rise remain unclear. Some studies suggest that YOCRCs have more aggressive biology. Here, we compare tumor-associated T cell repertoires between patients with YOCRC and average-onset CRC (AOCRC). A robust, focused T cell response is a positive prognostic indicator; therefore, we hypothesized that YOCRCs demonstrate lower T cell abundance and greater T cell diversity than AOCRCs. Methods: The discovery cohort included 242 patients with histologically confirmed Stage I-IV CRC who underwent surgical resection at Cleveland Clinic from 2000 to 2020 and consented to a biorepository. YOCRC was defined as < 50 years at diagnosis (N = 126), and AOCRC as > 60 years (N = 116). DNA was extracted from frozen tumors, and T Cell Receptor (TCR) abundance and clonality were measured using immunoSEQ (Adaptive Biotechnologies). Following quality control, logistic regression models were used to evaluate the associations between TCR repertoire features and age of onset, adjusting for sex, race, tumor location, and stage. Findings were replicated in 152 YOCRC and 1,984 AOCRC cases from the Molecular Epidemiology of Colorectal Cancer Study with adjustment for sex, Jewish ethnicity, tumor location, and stage. Results: YOCRC patients were more likely to have left-sided tumors and be diagnosed at advanced stages in both cohorts. In the discovery cohort, YOCRC tumors had significantly lower TCR clonality (higher T cell diversity) compared to AOCRC tumors in a multivariable model adjusting for sex, race, tumor location and stage (OR: 0.38, 95% Confidence Interval (CI): 0.25-0.56, p < 0.0001). This association was also observed in the replication cohort (OR: 0.74, 95% CI: 0.62-0.89, p = 0.0013). In the replication cohort, further adjustment for microsatellite instability status did not substantially change the association (OR: 0.73, 95% CI: 0.61-0.88 p = 0.0012). When restricting to microsatellite stable tumors, clonality remained statistically significant in both the discovery and replication cohorts. No significant difference in TCR abundance was observed between YOCRC and AOCRC in either cohort. Conclusions: Higher T cell repertoire diversity, indicating a less focused intratumoral T cell response, is more frequently observed in YOCRC. Further studies are warranted to investigate the role of T cell diversity in the etiology and outcomes of YOCRC.


In this study, Bi2Te3 thin films were deposited on SiO2/Si(100) substrates by pulsed laser deposition (PLD) at 250 °C. The films were then annealed in-situ in the deposition chamber at various annealing temperatures (Ta) ranging from 200 to 300 °C. The microstructural, morphological, and nanomechanical properties of the Bi2Te3 thin films were investigated by X-ray diffraction (XRD), scanning electron microscopy, and nanoindentation techniques, respectively. The XRD results indicated that all the Bi2Te3 thin films have high crystalline quality with predominant (0015) texture. Nano-indentation measurements performed with a Berkovich nanoindenter operating under the continuous contact stiffness measurement mode revealed that both the hardness and Young's modulus of the Bi2Te3 films decreased with increasing Ta. In addition, the water contact angle measurements were carried out to delineate the effects of annealing on the changes in the surface energy and wettability of the films.


With the expansion of the production scale the blast volume supplied by one single air compressor can hardly meet the demand of the instruments in the normal production.The present paper elucidates the possible problem in the parallel running for multiple air compressors and its solution plan and practical implementation of the plan.


This book is the proceedings of a symposium held in June 1979 and bears the hallmarks of most such volumes-uneven quality, hurried production, and poor editing. The symposium itself must have been an interesting one, but the wide variety of topics covered, while admirable for oral presentation, is much less satisfactory in a book. The problem stems partly from differing interpretations of'management'. A number of chapters relate almost entirely to genetic counselling, others to diagnosis, while other chapters on therapy of diabetes and thyroid disease have little relationship to genetics. A major criticism must be the apparent lack of editorial influence on selection of material, presentation, and correct use of English. The poor quality of production, though no doubt rapid, adds to the impression of a series of manuscripts hastily bound together, and makes tiring reading. Having made these criticisms, there are some really valuable contributions. The chapter by Crawford on Turner's syndrome is an excellent example of the value of long term supervision in achieving optimal growth and maturation and in preventing complications. Crawford contributes a further valuable chapter on management of children with ambiguous genitalia, while other worthwhile contributions are on sickle cell disease, cystinosis, and the mucopolysaccharidoses, by Lehmann, Schulman, and Leroy, respectively. Rosenberg and Scriver both contribute clear general reviews on the approaches to therapy. All in all, this book is a missed opportunity. There is a need for a comprehensive book on management of various genetic disorders, but it will need to define its aims and scope clearly and to be carefully planned. A conference report, however good some of its contributors, cannot fulfil this need.


Objective To explore new non invasive approach to measure the pulmonary artery diastolic pressure (PADP) with MRI.Materials and Methods The furthest retrograde velocity of main pulmonary in 40 patients with pulmonary regurgitation (PR) were measured with phase contrast MR imaging, and the results were compared with that from cardiac catheterization. Both the sensitivity and specificity of PADP obtained from phase contrast MR imaging were evaluated with linear relation and regression analysis.Results PADP measured with phase contrast MR imaging and with right cardiac catheterization was 4.82±1.24 mmHg and 4.52±2.00 mmHg, respectively, no significant difference was found (t=1.45, P0.05), but a significant correlation existed between the two (r=0.94, P0.01) with the regression equation y=0.82x+4.58. Conclusion MRI is a new reliable technique for evaluating PADP in patient with PR.


The invention discloses a three-drum unattended turbulence profile measurement device composed of a communication drum, a connecting drum and a driving drum in butt joint. A high-pressure plunger pump and a hydraulic electromagnetic valve control hydraulic oil mass change to change buoyancy of the profile measurement device in seawater, and the measurement device is enabled to automatically submerge and float in seawater. A turbulence measurement probe arranged outside a driving drum bottom endcap measures turbulence parameters, and collected turbulence data are sent out via a collection control module, a communication module and a satellite antenna. The three-drum unattended turbulence profile measurement device is of the three-drum structure, so that stability of the device is improved; the measurement device can submerge and float automatically and quickly, unattended turbulence observation is realized, and the requirement on turbulence observation under severe sea conditions is met.


The invention discloses a flat panel display and a display data control method of the flat panel display, which are applicable to deciding the polarity when the display data is outputted. The display data control method comprises the following steps: receiving first display line data of first pixel data displayed at a first pixel, and deciding how to adjust the polarity when second pixel data displayed on a second pixel is outputted in second display line data according to the relationship between the first pixel data and a certain preset range; if the polarities when the first pixel data andthe second pixel data are outputted are decided to be the same, fixedly leading the polarity when pixel data displayed on the follow-up pixel which is related to the position of the first pixel in each follow-up display line data which is continuously received to be the same with the polarity when the first pixel data is outputted within a preset time length. The display data control method can adjust the polarity of data supply under the possible arrangement situation of the display data and reduce the image instability phenomenon caused by the change of the data polarity.


The article considers the level and dynamics of labor productivity in the Kemerovo region in comparison with the Russian Federation. The research objective was to reveal the current state of the local labor productivity. A number of statistical problems were revealed as a result of an analysis of labor productivity dynamics and highly productive jobs. The author determines the main factors affecting the level of labor productivity and suggests measures to eliminate them. The study was based on statistical data, as well as research results of Russian and foreign analysts. The analysis involved both absolute and relative values, methods of comparison, grouping and analysis. The author believes that the low level of labor productivity in the region can only be increased by the combined efforts of the state and individual enterprises. The set of measures should include reduction of the depreciation of fixed assets, improvement of statistical reporting, raising awareness and control over labor productivity, raising the level of skills and personal interest of employees in high-performance work, and stimulating enterprises.


The effect obtained in labor resources intensive management by Shaanxi Electric Power Corporation is summed up. Combined with the reality in Shaanxi Electric Power Corporation,the exited problems are analyzed.The corresponding measures are put forward for improving labor resources intensive management.


Background Using cell-based medicinal products (CBMPs) represents a state-of-the-art approach to reducing 88 general immunosuppression in organ transplantation. Accordingly, The ONE Study Consortium tested 89 multiple regulatory CBMPs in kidney transplant (KTx) trials. Here, we report primary analysis results 90 for safety of regulatory CBMPs when combined with reduced immunosuppressive treatment in this 91 first ONE Study publication. Seven investigator-led single-armed trials were conducted internationally in living-donor KTx 94 recipients (60 week follow-up). One single-arm trial, the Reference Group Trial (RGT, n=66), 95 represents a "standard-of-care" group given basiliximab, tapered steroids, mycophenolate mofetil 96 (MMF) and tacrolimus. Data from six non-randomized phase I/IIa cell therapy group (CTG) trials were 97 pooled and analyzed, where patients (n=38) received one of six CBMPs containing regulatory T cells, 98 dendritic cells or macrophages; patient selection and immunosuppression mirrored the RGT, except 99 basiliximab induction was substituted with CBMPs and MMF tapering was allowed. The primary 100 endpoint was biopsy-confirmed acute rejection (BCAR); adverse event (AE) coding was centralized. the RGT recipients resulted in a 12·1% BCAR (expected range: The 6 CBMPs for the parallel CTG trials were to a combined total patients, with an overall of 15·8%. 15 patients (39·5%) were from MMF and AE data BCAR from all six CTG trials no Fewer episodes of in to test those cell products in early-phase clinical trials. The six CBMPs developed and tested in six parallel cell therapy group (CTG) trials (<12 patients each) in The ONE Study included two polyclonal T regulatory (pTreg), two donor-antigen reactive Treg (darTreg), one tolerogenic DC (ATDC) and one regulatory macrophage (Mreg) cell products. Central to the concept of The ONE Study was that all CBMPs be tested using the equivalent patient population of living-donor kidney transplant (KTx) that receive the identical background immunosuppressive treatment, placing testing of the six CBMPs on a directly comparable basis. Also fundamental to this study was that a larger Reference Group Trial (RGT) be conducted on an equivalent patient population using standard-of-care immunosuppression. While the RGT is not strictly a true control group due to inclusion of basiliximab place of cell therapy, it serves two purposes. First, since we have applied our CBMPs under similar, but reduced, immunosuppression, the RGT provides a recognized standard-of-care benchmark to assess whether currently expected outcomes are generally attainable with regulatory cell therapy with less immunosuppression. Second, with a standard-of-care RGT, performance of centralized immune monitoring allows for reliable detection of potential immunological changes caused by cell therapy. Here, we present the special design, clinical data, safety results and immune monitoring data of the ONE Study RGT and combined CTG group of trials, which is intended as a foundation for further regulatory cell therapy trials in organ transplantation.


The impacts of nanoplastics (100 nm) on terrestrial systems are unclear at this time. Due to the utilization of sewage sludge, plastic particles are likely to accumulate in these systems. The current research investigates how Solanum lycopersicum seed germination and growth are affected by fluorescence polystyrene (Flu−PS), humic acid (HA), and a Flu−PS+HA combination (tomato). Following 24 h of interaction between Flu−PS and HA, our report details the development of an eco-corona with a significant increase in hydrodynamic size. Plant growth, seed germination, and chlorophyll content were all enhanced by the eco-coronated Flu−PS.Additionally, we discover that seeds treated with Flu−PS+HA demonstrated a germination rate of 90%, compared to just 65.8% for seeds treated with Flu−PS alone. Chlorophyll (a, b, and a + b) content measurements indicated that HA-treated groups and Flu−PS+HA-treated groups had considerably higher levels of chlorophyll (a, b, and a + b) than Flu−PS-treated groups (Flu−PS: 3.18 mg g−1, 2.12 mg g−1, and 3.89 mg g−1, HA: 5.96 mg g−1, 4.28 mg g−1, and 6.36 mg g−1, and Flu−PS+HA: 4.17 mg g−1, 3.01 mg g−1, and 6.08 mg g−1, respectively). In a similar manner, the HA and Flu−PS+HA treatment groups showed lower ROS levels than the Flu−PS treatment groups. In addition, we discovered that the activity of the antioxidant enzymes superoxide dismutase and catalase was lower in the groups treated with HA and Flu−PS+HA than in the groups solely treated with Flu−PS. The results demonstrated that HA significantly lessens the toxicity caused by Flu−PS, while also promoting the germination and growth of Solanum lycopersicum seeds. The related decrease in toxic effects may be ascribed to the establishment of an eco-corona on the Flu−PS. We think that the use of eco-coronas is a technique for safeguarding plants against xenobiotics such as nanoplastics.


The gamma-ray spectra from the nuclear reactions 10B+d, 11B+d, and 27Al+p have been measured with a pair spectrometer. Lines are found from 10B+d at 8.88±0.06 MeV., 6.7±0.15 MeV., 6.4±0.15 MeV., and 4.38±0.05 MeV.; from 11B+d at 4.44±0.05 MeV.; and from 27Al+p at 12.12±0.1 MeV., 10.46±0.07 MeV., and 7.62±0.1 MeV. The correlation of these gamma-rays with the energy levels of the nucler involved is discussed


This chapter attempts to clarify two main cultural products of the Deep Sea Canoe Movement (henceforth DSCM), which is rooted in a recently evolving evangelical ethno-theology among To'abaita speakers on the island of Malaita, Solomon Islands.The books and the film are cultural products that are part of attempts by the authors cum producers to attract local and worldwide attention and to seek acknowledgement for their identities as prophets and people with a special connection to Israel. The chapter concludes that on the one hand we see a turn inwards when To'abaitans reflect on their kastom and the profane world while trying to become holy, while on the other hand the Deep Sea Canoe Movement is dedicated to the word of God and the mission of straightening the world by prayer, beginning in the Pacific and Australia. Keywords:cultural products; Deep Sea Canoe Movement (DSCM); ethno-theology; Solomon Islands


Employing his methodological scalpel, Ildefons Cerda cut into the urban fabric and created just as many problems as he solved. Today, the legacy of the piecemeal approach to urban life advocated by Cerda persists in its instrumentalist and inadequate focus on the built environments of cities without paying enough attention to the complex relationship between social, cultural, and political factors out of which the city is produced. A Lefebvrian reading of Cerda's urban theories (in his Teoria de la construccion de las ciudades, Teoria de la viabilidad urbana, and Teoria general de la urbanizacion) highlights the methodological and philosophical premises that may have prevented the Catalan planner's socialist-utopian dreams from being realized.


Shoba Arun, Development and Gender Capital in India: Change, Continuity, and Conflict in Kerala. New York, NY: Routledge, 2018, 186 pp., ₹8,225 (hardcover). ISBN: 978-1-138-22196-3.


In recent years, a major growth area in applied natural language processing has been the application of automated techniques to massive datasets in order to answer questions about society, and by extension people. Sociolinguistics, which combines anthropology, statistics and linguistics (e.g. Labov 1994, 2001), studies linguistic data in order to answer key questions about the relationship of language and society. Sociolinguists focus on frequency and patterns in linguistic usage, correlations, strength of factors and significance, which together reveal information about the sex, age, education and occupation of speakers/writers but also their history, culture, place of residence, social relationships and affiliations. The findings arising from this type research offer important insights into the nature of human organizations at the global, national or community level. They also reveal connections and interactions, the convergence and divergence of groups, historical associations and developing trends. In this paper, I will introduce sociolinguistic research and the nature of sociolinguistic field techniques and sample design. I will argue that socially embedded data is critical for analyzing and discovering social meaning. Then, I will summarize the findings of several case studies. What does the use of a 3rd singular morpheme -s, as in (1), tell us about the history and culture of a community (Tagliamonte 2012, 2013)? How is quotative be like, (2), spreading in geographic space (Tagliamonte to appear)? What is the mechanism that underlies linguistic change (Tagliamonte & D'Arcy 2009) and by extension cultural trends and projections? 1. The English people speaks with grammar. 2. I was like, "Hey how are you going?" And hes like, "Im fine." Using sociolinguistic datasets, the answers to these questions have successfully addressed prevailing puzzles and offered solutions to real world problems. However this type of research is only be as good as the quality of the data, the capability of the technologies for extracting and analyzing what is important, and the relevance of the socially cogent and statistically sound interpretations. I will argue that Sociolinguists and Computational Scientists could be powerful allies in uncovering the complex structure of language data and in so doing, offer unsurpassed insight into varying human states and conditions.


The congenital missing of mandibular second premolars is among the common dental anomaly in children. When a second premolar is diagnosed as congenitally missed, we should consider many factors influencing the treatment plan such as patient's age, states of roots of 2nd primary molar, degree of crowding, skeletal growth pattern, facial profile, procumbency of the incisor and lower facial height, etc. The mineralization of the second premolars begins in the majority of cases at the age of years, but this period varies more widely than those for other permanent teeth. Also, mandibular second premolars show the greatest variations in differentiation and calcification. For this reason, aplasia of this group of teeth cannot be diagnosed at early age and with the same degree of certainty. From the clinical studies with 2 cases and some literature review on late development of second premolars, it could be summarized as follows : 1. The 2 cases showed marked delay in the development of mandibular second premolars. 2. After the crypt formation, the speed of calcification seemed nearly normal, suggesting that the delay was due to differentiation rather than calcification. 3. When one is encountered with similar conditions, it would be desirable to consider the possibility of delayed tooth development.


We prove that if the average number of Sylow subgroups of a finite group is less than 415\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${{41} \over 5}$$\end{document} and not equal to 294\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${{29} \over 4}$$\end{document} , then G is solvable or G/F(G) ≅ A5. In particular, if the average number of Sylow subgroups of a finite group is 294\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${{29} \over 4}$$\end{document} , then G/N ≅ A5, where N is the largest normal solvable subgroup of G. This generalizes an earlier result by Moretó et al.


This study draws on the narrative accounts of eight students with disabilities at a small liberal arts college in order to understand the connections between disability and student engagement. We found that disability plays a mediating role in the classroom; there are variations in access to institutional support; supportive peer networks are important' and disability identity has a variable salience for these students. We also found that engagement for students with disabilities is multi-dimensional and multi-faceted. We include recommendations for supporting engagement for students with disabilities as well as suggestions for future research. Citation: Kimball, E., Friedensen, R., & Silva, E. (Forthcoming). Engaging disability: Trajectories of involvement for college students with disabilities. In E. Kim & K. C. Aquino (Eds.), Disability as Diversity in Higher Education: Policies and Practices to Enhance Student Success. New York: Routledge.


Payable account analysis is short term liabilities to be paid in a period of a year including loans, short term loans and short term obligations such as taxes in progress and interest. Liquidity ratio describes company in complying with itsshort term obligations when they are mature. Its linkage with current debt ratio is the sooner the current debts are paid the more exact the impact of liquidity ratio level of the company to pay its payable debts.

The purpose of this study is to look for information and to find out the truth of how far payable account turnover is influenced by the liquidity ratio. The evaluation result of this study is that a good working capital turnover will result in profitability, so the company has power to run its business properly.


Abstract The synthesis and the enzymatic studies of modified oligonucleotides containing a PNA modified PNA-DNA dimer block and a new acyclic racemic serinol nucleoside is described. We show that both, the PNA-DNA dimer block1 and the modified PNA-spacer (acyclic serinol nucleoside)2 can be used as modified templates for the enzymatic generation of single stranded DNA. Degradation studies of the oligonucleotides containing the PNA-DNA dimer block with snake venom phosphodiesterase show that the modified oligonucleotides are stable towards exonucleolytic degradation.


High resolution Cosmo-SkyMed SAR images are used for oil spill detection and ship identification on the Mediterranean Sea, in the framework of PRIMI Pilot Project currently developed by Italian Space Agency (ASI). The system consists of four components, two of them devoted to the analysis of the SAR and Optical satellites images for the slicks detection, an oil spill forecast subsystem and a central archive that provides web-gis services; a preliminary version of the system is already operational. Besides the slicks relevant information and detected ships on the analyzed scene, the system also provides meteorological and oceanographic information. The architecture of the system, the operational scenario and the preliminary results are presented.


Drawing of glass fibers is an important industrial process used for the manufacture of a variety of materials ranging from optical communications cables to fiber filter media. A variety of machines exist for performing the drawing function, but all share similar problems with control of the fiber diameter and breakage of the fibers during the extrusion process. In many cases, control systems are not configured to monitor the most critical process variables, but instead use only furnace crown temperature. Upsets in disturbance variables such as ambient temperature are compensated manually by operators, usually only after significant problem with fiber breakage occur. This work seeks to provide a better understanding of the effects of important process variables on the key quality and production parameters such as fiber diameter and production rates.


Extramural activities in the view of graduate students of Dentistry Graduation Course The participation of students' health area in extramural activities makes possible the knowledge and performance in the structural dimension of public health services. It is part of the graduation curriculum guidelines of dentistry graduation courses and of law n.8080 recommendations that regulates the National Health Service (SUS). The aim of this study was to evaluate the Extramural Dental Service (SEMO) and its corresponding activities, under graduate students' point of view of FOA-UNESP. A cross-sectional study was carried out, with a quali-quantitative approach. A questionnaire was sent by mail approaching several aspects related to the SEMO, for 76 former students graduated in 2003. The data were submitted to the quantitative analysis though the software Epi Info. For the interpretation of the open questions, it was used the model Analysis of Content. Of the total, 47% returned answered, and 100% of those affirmed the participation in the SEMO was satisfactory. Several factors were related to the SEMO contribution in the professional formation, like the knowledge of the reality and social context (21.2%), the capacity of adaptation of available resources (18.2%) and the contact with the reality (15.2%). Through the Association of Words Technique, categories as "Importance of SEMO" (100%), "social reality" (53.1%) and "teaching" (40.6%) were identified. Among some difficulties cited, it was listed the deficiency in the infrastructure (63.6%). The objectives proposed by the SEMO were fully and reasonably reached for 36.4% and 63.6% of the graduated students, respectively. The graduated students evaluated the SEMO as a valid experience, contributing in their qualification to act with efficiency and resolution capacity in the National Health Service. DESCRIPTORS Dental education. Community institutional relations. Health services. Educational measurement. Community dentistry. Dental staff. § REFERênCIAS BIBLIOGRáFICAS 1. Bardin L. Análise de Conteúdo. 3a ed. São Paulo (SP): Ed. 70,


We utilize terahertz time domain spectroscopy to investigate thin films of the heavy fermion compound SmB6, a prototype Kondo insulator. Temperature dependent terahertz (THz) conductivity measurements reveal a rapid decrease in the Drude weight and carrier scattering rate at ~T*=20 K, well below the hybridization gap onset temperature (100 K). Moreover, a low-temperature conductivity plateau (below 20K) indicates the emergence of a surface state with an effective electron mass of 0.1me. Conductivity dynamics following optical excitation are also measured and interpreted using Rothwarf-Taylor (R-T) phenomenology, yielding a hybridization gap energy of 17 meV. However, R-T modeling of the conductivity dynamics reveals a deviation from the expected thermally excited quasiparticle density at temperatures below 20K, indicative of another channel opening up in the low energy electrodynamics. Taken together, these results suggest the onset of a surface state well below the crossover temperature (100K) after long-range coherence of the f-electron Kondo lattice is established.


This article analyzed the present situation of the Netcom and the Telecom Internet interconnected. Points out the question that the existence of interconnection and intercommunication quality is not good. Proposed four kind of practical technologies about the optimized interconnection. Introduced its realization principle, typical application and the application effect separately. The article gives the specify to the technology of double routing, and think the technology of double routing has the widespread application prospect.


The characteristic collection in our country is rich and scattered.Libraries lack of effective cooperation and sharing mechanism to match more characteristic collection and needed readers.The paper reference the distributed cooperation storage mode used for low utilization rate documents proposed by international libraries as a practical way to realize cooperation and sharing of characteristic collection in China.


Several surveys were carried out between 1985 and 1988 along the Oman coast between Bandar Khayran to the north and Ra's Sharbitat, at the Dhofar border, to the south (Biagi & Maggi 1988, 1989), as part of a project carried out by the Italian Archaeological Expedition directed by Prof. M. Tosi. Particular thanks are due to Major W. Foxton of the Sultan Army Forces and to Dr R. Salm of the Ministry of Commerce and Tourism who provided every sort of logistic support. Dr R. Maggi took part to an intense campaign in the spring of 1987, while other members of the mission contributed to the discovery of sites, namely Drs E. Isetti, R. Nisbet, A. Pessina and E. Starnini. Drs H. Quitta and K. Rassmann are to be thanked for producing a set of radiocarbon dates from shell samples supplied to the laboratory of the GDR Academy of Sciences in Berlin. East of Muscat, the bay of Bandar Khayran was accurately investingated mainly by boat. Several shells-middens surround this bay (BK4, BK5, BK7, BK10, BK11, BK12), while the small island where BK3 is located produced oval shaped stone structures, very small earth heaps, probably related to burials, and Area shell scatters delimited by stone circles. One of these scatters gave the dates of 5210 ?60 BP (Bln-3388/I) and 5210 ?60 BP (Bln-3388/II) (fig. 1). The chipped stone assemblage from site BK3 consists of a few bladelets and two instruments chipped from quartz and a few flints (fig. 2, 2-4). The presence of one long limestone bead with perforations at both edges (fig. 2, 1) has parallels at the contemporary sites of Dhofar (Weisgerber pers. comm., 1987). Also the other Bandar Khayran shell-middens yielded a poor quality chipped stone industry mainly obtained from quartz (fig. 2, 5-10). The radiocarbon evidence shows that BK7 is more or less contemporary to BK3. The C14 dates from this site range between 5200 ?70 BP (Bln-3390/I) and 5140 ?70 BP (Bln-3390/II), while BK5 was dated to 5580 ?50 BP (Bln-3389/I) and 5700 ?60 BP (Bln-3389/II) and BK11 to 5720 ?60 BP (Bln-3648/I) and 5870 ?60 BP (Bln-3648/II) on Area samples. Only two small sites are known W of Bandar Khayran, that is Yiti (YTl) on the beach E of the modern village, and Khawr Yenkit (KTl), a small scatter of shells on a cape inside the khawr. Further S, the shell-midden of BDD1 had already been discovered during previous research. Khor Milkh (KM1) was found by Phillips and Wilkinson (1977) and dated to 5130 ?90 BP (ANU-2813). The excavation of this midden as well as of the nearby KM2, were later resumed by the T?bingen Archaeological Mission (Uerpmann M., forthcoming). Two sites are also known S of the Quriyat mangrove swamp. DG2, not visible from the sea, is on a hidden terrace. It is composed of many stone walled houses, while DG1, along the steep terraced coastline


We introduce a new determinantal method to count cycle systems in a directed graph that generalizes Gessel and Viennot's determinantal method on path systems. The method gives new insight into the enumeration of domino tilings of Aztec diamonds, Aztec pillows, and related regions.


The wellbore condition and its corresponding effect on log readings must be assessed and corrected for during log quality control and formation evaluation. Differences arise between measurement-while-drilling (MWD) and wireline neutron density, photoelectric factor (PEF) logs made in the same well because the two systems respond differently to the wellbore environment. Differences also occur because of changes in wellbore condition over time


The regularization method is applied with sparsity constraints to seismic waveform inversion in this paper.To weaken the smoothness requirement of the sparsity constraints,the Bayesian inference is introduced and a series of samplings which satisfies the posterior distribution are generated.In numerical examples,statistically significant results of samplings such as conditional expectation,variance and confidence interval are recorded.Numerical results are presented to illustrate that,without requirement of smoothness,the regularization method with sparsity constraints has a good ability to identify the edge of the media with cavity and layered models.Especially,when the observation data are reduced,the regularization method with sparsity constraints can still provide reasonable inversion results.


Purpose
The purpose of this study is to evaluate whether focus on social output affects the efficiency of MFIs. Inclusive growth is the key developmental aim for many developing countries, including India. The role of microfinance institutions (MFIs) in promoting financial inclusion is widely applauded. However, to achieve financial sustainability, MFIs have become highly commercialised and are seen to have drifted away from their social mission. Various studies have shown the efficiency of MFIs on financial parameters. MFIs being a social enterprise, it is important to include social output among the efficiency parameters.

Design/methodology/approach
This study attempts to compare the efficiency of MFIs with and without social performances across the various size of MFIs based on their asset, i.e. large, medium and small. This study uses Data Envelopment Analysis (DEA) for assessing an MFI's efficiency. For calculating the social output score, the Gutman Scale is used. Efficiency is calculated with and without social output, and the resulting scores are compared to assess the impact of social performance on the efficiency of MFIs.

Findings
The results of this study allow us to conclude that with the inclusion of social output, the efficiency of MFIs improves across various categories. In terms of social performances, it is concluded that MFIs are targeting women and mostly working in rural areas but have neglected issues like health and education.

Originality/value
The findings of this study will help MFIs in formulating their mission and vision statements and in achieving the objective of financial inclusion without experiencing mission drift.


Periodontitis present as local destructive disease in periodontium and thus require a much specific treatment. The traditional scaling and root planing therapy alone is not sufficient for treatment of moderate to severe periodontal pocket because of its relative time consumption and inaccessibility in deep pocket. Thus systemic and local administration of drugs is recommended. Local Drug Delivery (LDD) provides specificity by acting on the site of infection. Local drug delivery systems have been used from late 1970's. They come in various forms like gel, films, fibers, nano-particles, micro-particles, vesicular systems etc. The use of herbal medication as a Local Drug Delivery agent came in limelight in 2011;the different agents available areNeem, Aloe-vera, Lemon-grass, Green tea, Tea tree oil, Curcumin, Oak, Coriander, Babul, Bakul. Keyword:Chronic Periodontitis, Herbal agent and Local Drug Delivery.


With the rapid increase in human density, development, and mobility in urban areas, the need for logistics distribution systems is increasing which is an important part of connecting industries with their consumers. Thus, route planning is an important thing for the industry. Therefore, this paper proposes a comparison of several vehicle routing problems algorithms and test the routes that have been obtained on a simulation system based on real conditions. Our proposed algorithm consists of Mixed Integer Linear Programming (MILP), Clarke-Wright and Reinforcement Learning algorithm using Markov Decision Process. Digital maps, customer data and route planning results will be converted into a SUMO simulation. We compare the performance of the algorithm with parameters consisting of the number of routes, distance traveled, computation time and simulation time. The experimental results show that the MILP algorithm has the best performance with the most optimal route results, but other algorithms have a lower computation time.


In organizing a project's tasks into manageable work packages (i.e., forming a work breakdown structure), trade-offs arise. Defining smaller work packages increases project complexity and workload,...


188Re-HEDP have been prepared with 188Re eluted from a 188W/188Re generator.The best labelling condition is 5 mg HEDP, 2.0mg SnCl2, and 1 mg Vitamin C, PH2.0.Labelling yield is greater than 95%. The in vitro stability of 188Re-HEDP is good in 12 hours. By adding some adjunct reagent in preparation, femur uptake raised to 7.86 ±1.62%/g after 4 hours. As compared with control uptake 1.92±0.61%/g in mice (P0.01). Clear whole body images of rabbit has been obtained. Thereby 188Re-HEDP is a good potential candidate for the treatment of bone tumor.


As a promising sintering technique, flash sintering utilizes high electric fields to achieve rapid densification at low furnace temperatures. Various factors can influence the densification rate during flash sintering, such as ultrahigh heating rates, extra‐high sample temperatures, and electric field. However, the determining factor of the densification rate and the key mechanism during densification are still under debate. Herein, the densification and grain growth kinetic during flash sintering of 8 mol% Y2O3‐stabilized ZrO2 (8YSZ) is studied experimentally and numerically using finite element method (FEM). The roles of Joule heating and heating rate on the densification are investigated by comparing flash sintering with conventional sintering. An apparently smaller activation energy for the material transport resulting in densification is obtained by flash sintering ( Qd  =424 kJ mol−1) compared to the conventional sintering ( Qd  = 691 kJ mol−1). In addition, a constitutive model is implemented to study both the densification and the grain growth during flash and conventional sintering. Furthermore, the effect of electrical polarity on the density and the grain size evolution during flash sintering of 8YSZ is also investigated. The simulation results of average density and grain size inhomogeneity agree well with the experimental data.


Abstract This article identifies and discusses six specific factors that distinguish group therapy from family therapy. These differences have implications for therapist training and practice. Failure to understand and acknowledge that group therapy and family therapy are distinct therapeutic systems diminishes the quality of therapist preparation programs as well as the delivery of therapeutic services


Similar to many other Chinese ancient works,the book of Lie Xian Zhuan has been gradually improved in its long course of circulation.The Lie Xian Zhuan,which was completed before mid-Donghan Dynasty,is quite different from the present version,and the present version was probably finalized between Yonghe Year 5 of Shun Emperor(140 DC)and Tai'an Year 2 of Xijin Dynasty (303 DC).In its circulation after the above period,the book has been revised on some items.


Auto transmission in vehicle need heat exchanger for cooling transmission working oil. In this study, find the test method and condition of prediction heat dissipation in transmission cooling system appling two heat exchangers and develop new high performance oilcooler that can satisfy one heat exchanger for cooling transmission oil system that use currently with two exchangers.


Modified atmosphere packaging (MAP) was evaluated for respiration rate, color, total phenolic content (TPC), antioxidant activity DPPH, flavonoids and pigments of fresh-cut Tropic Beauty peach. Modified atmospheres (21% O2 [Control], 5% CO2 [MAP1], 8% CO2 [MAP2] and 0% O2 [MAP3]) were evaluated for storing fresh-cut peaches for up to 10 days in temperatures of 5oC. MAP significantly (p<0.05) affected the proprieties investigated as compared to control. Peaches with MAP3 have higher respiration(p<0.05) respiration rate than the peaches with the other treatments. Fresh-cut peaches in MAP2 showed more stable (p<0.05) carotenoid and anthocyanin contents, better attributes in the bioactive compounds. MAP1 and MAP2 exhibited better antioxidant proprieties at low storage temperature (5oC) for up to 10 days storage and similar result was verified by principal component analysis used where modified atmosphere was observed as major factor.


A battery of protection and resource performance tests were conducted using commercial internet security suites designed for general purpose usage with a Windows 8 personal computer (PC). Six classes of PC users were identified: Internet addict; network businessman; socializer; basic user; gamer; self-presenter; infrequent user. Recognizing that practical Internet security is different for each of these user groups, the importance of each component protection and resource performance test was assessed independently for each PC user group. By weighting component results to match relative importance for each user group, separate overall comparative assessments of the tested internet security suite products were obtained separately for each user group. From this, a more effective assessment of the value of commercial anti-malware protection is obtained specific to a customer's PC usage. When third party commercial anti-malware products were compared to the protection application provided by Microsoft, the average improvement ranged from 5% to 10% when measured separately for each PC user group.


A novel chemical modification employing TCNQ is proposed as a preparation technique of ion sensing membrane. The silver ion sensor which links coated wire electrode to the gate lead-wire of a conventional FET showed linear response to silver ion activity in the range from 10-^5 mol dm^-3 to 10-^1 mol dm^-3 with an almost Nernstian slope. Hg^2+ interfered strongly with Ag(TCNQ) thin film, however, the selectivity coefficients for other ions were below 10-^4. The silver ion sensor gave stable potential after a slight drift during 2.5 h. The response time of the proposed sensor was less than 10 s from low to high concentration and in the reverse case the response time became less than 30 s.