STANLEY RESOR Stanley Resor W A YALE undergraduate, class of 1901, Stanley Burnet Resor assumed that he would enter the family stove manufacturing business, founded in Cincinnati in 1819. He hoped instead to teach economics, for the study fascinated him. He did neither. During more than a half century with the J. Walter Thompson Company -its President 1916 to 1955, its Board Chairman 1955 to 1961-he became a dominant and almost legendary force in marketing and advertising. Stanley Resor helped pay his way at Yale by tutoring in Latin. During the summers he sold a history of the Bible in southern Ohio and distributed samples of Pearl Soap at factory gates, learning firsthand the rigors of door-to-door selling and the hard facts of product resistance. In his senior year he won the James Gordon Bennett prize of $60 in economics. On return to Cincinnati, he found there was no need for him to assist in the demise of the failing family business, but getting a job elsewhere proved difficult. Self-made American businessmen of 1901 were suspicious of college graduates. When, after other rebuffs, the young Resor applied to Globe-Wernicke, Otto Wernicke demanded By JAMES PLAYSTED WOOD The Curtis Publishing Company


This study is about the development of a Model Apparatus for the Lecture-Demonstration of the Human Eye. The aim is to design and construct an apparatus that mimics the optical principles of human eye in carrying out the processes of accommodation, the common vision defects and their corrections using appropriate lenses. The study comprises three areas: I.) design and improvisation II.) materials selection III.) construction and testing.


The invention relates to the field of immunology specifically to cancer immunotherapy, and more particularly to immunotherapy combination (combination), and therapeutic methods for the removal of anti-tumor cell growth and / or these cells. The method disclosed in the present invention is based on the tyrosine residue receptor (receptor tyrosine kinase Kana, RTK) and block (blockade) of the ligands of these receptors with protein kinase activity in (tyrosine redidues). Immunotherapy combination is disclosed to cause the passively (passive) and active (active) means the RTK receptor and / or blocking of their combination by the combination of immunotherapy. Mentioned processes (procedures) can be applied to different clinical stages with tumors of epithelial origin that over-expression (over-express) of such receptors (epithelial origin) patients. Regardless of whether the treatment process is used as for patients with advanced disease or reinforcing treatment (adjuvant therapy), the combination of active and passive immunotherapy can be simultaneous or sequential.


We have found that Chlamydomonas reinhardtii cells contain an ATPdependent topoisomerase activity that supercoils circular DNA in vitro. Subsequent addition of a type I topoisomerase eliminates the supercoils. Like bacterial gyrase, this activity is inhibited by low concentrations of novobiocin (<0.1 p1) and by nalidixic acid (<0.1 mM). We have examined the effects of these topoisomerase inhibitors on accumulation of various chloroplast transcripts in vivo. Novobiocin differentially affected such transcripts; some transcripts became more abundant while many others were reduced in the presence of this drug. Nalidixic acid on the other hand caused many transcripts to become more abundant albeit to varying degrees. Inhibitors of this algal topoisomerase specifically stimulate a family of related transcripts which we have previously shown to be under light-dark control. We discuss how the inhibitors of this topoisomerase might exert their in vivo effects. INTRODUCTION Photosynthesis requires precise interactions, in time and space, of many chloroplast proteins and membrane components (reviewed in ref. 1). In part, such interactions must depend upon regulation of the corresponding genes. Therefore, regulation of chloroplast genes, including effects of nuclear genes and of environmental stimuli on this regulation, is of great interest. Here we present evidence that an ATP-dependent supercoiling topoisomerase plays an important role in this regulation. Bacterial DNA gyrase is inhibited by novobiocin (2) and can be purified by affinity chromatography employing a novobiocin-sepharose column (3). Using such a column, we have partially purified an ATP-dependent topoisomerase activity from whole Chlamydomonas reinhardtii cells. This activity supercoils DNA in vitro, and such supercoiled DNA is relaxed upon subsequent addition of a type I topoisomerase. The supercoiling activity is inhibited by novobiocin and by nalidixic acid, a drug which also inhibits bacterial gyrase (2). In order to test for functioning of this topoisomerase in chloroplast C I RL Press Limited, Oxford, England. Volume 13 Number 3 1985 873 Nucleic Acids Research Nucleic Acids Research transcription, we have studied the effects of inhibitors of this enzyme (i.e. novobiocin and nalidixic acid) on accumulation of various chloroplast transcripts. In bacteria and their phages, these inhibitors and also mutations that alter gyrase activity have profound effects on transcription (reviewed in refs. 2 and 4). Novobiocin (or coumermycin) and nalidixic acid (or oxilinic acid) specifically inhibit the ATPase and nicking-closing activities, respectively, of DNA gyrase (2) thus causing a more relaxed state of the DNA (5,6). This change in DNA conformation, in turn, is thought to be one means by which these drugs affect transcription (2,7). Nalidixic acid, but not novobiocin, also damages the DNA and induces the SOS response (8). Consequently, the effects of these drugs on transcription are not identical. Chloroplast transcripts were studied by probing Northern blots of total cellular RNA with cloned chloroplast DNA fragments (Fig. 1), by probing Southern blots of restriction digests of total chloroplast DNA with in vitro labeled RNA, or by staining agarose gels with ethidium bromide. Of particular interest is transcript A which we have previously shown to be under light-dark control (11). Our results show that accumulation of this and various other chloroplast transcripts is affected by both novobiocin and nalidixic acid. MATERIALS AND METHODS Materials Algal strains CC-278 and CC-406 have been described elsewhere (11). Novobiocin (sodium salt) and nalidixic acid (free acid) were from Sigma. Epoxy-activated sepharose (6B) was from Pharmacia. T4 DNA polymerase was purified by Dr. L. Rowen in our laboratory and T4 polynucleotide kinase was purified by Dr. B. Walker. Topoisomerase I (calf thymus) was from Bethesda Research Laboratories and was used as prescribed by this supplier unless indicated otherwise. DNAase (RNAase free) was from Miles Laboratories. Restriction endonucleases were from Bethesda Research Laboratories and Boehringer Mannheim (Eco RI). Deoxynucleotide triphosphates were from PL Biochemicals, 5'-[a-32P]dCT (-800 Ci mmol 1) was from Amersham and 5'-[V-32P]ATP (-3000 Ci mmol 1) was from New England Nuclear. Plasmids pCP43, containing restriction fragment Eco RI 14, and pCP55, containing restriction fragment Eco RI 27 of the Chlamydomonas chloroplast chromosome (see Fig. 1 below), were obtained from J.D. Rochaix, University of Geneva, Geneva, Switzerland. Plasmid pRTl has been described (11). It contains a 0.8 kb subfragment of restriction fragment Hpa II 5 (-8.0 kb) of the chloroplast chromosome.


The present invention provides a communication apparatus and a signal transmission method. Its object is, in a low-speed signal and the speed is an integral multiple of the high-speed time-division multiplexed signal transmitted in the network, even if the communication terminal apparatus does not correspond to the high-speed signal can be accurately extracted from the received signal clock. In order to achieve this object, as OLT (100b) communication apparatus comprising: a repetitive pulse which is the same width to generate the low-speed signal pulse generating unit (130b); and a pulse superimposing unit (140b), which is superimposed by the pulse generating unit of the high-speed signal ( 130b) generated pulse, so that low-speed clock can be extracted.


The purpose of this study was to see how the novel coronavirus disease (COVID-19) crisis-affected customer purchasing behavior in the Indian garment industry. The nationwide shutdown resulted in a significant shift in consumer buying habits.

For fashion apparel brands and businesses to understand what value means to consumers and identify growth prospects during the COVID-19 pandemic is critical.

While analyzing customer buying behavior, we took age, spending, preferences, frequency of purchase, financial constraints, budget changes, style changes, and other factors into account. We conducted a survey, and the results were used to analyze the change in buying behavior of customers. After conducting primary research, the assumptions were solidified. The information for this study was acquired via distributing the questionnaire via internet platforms. According to the statistics, the most popular categories throughout the pandemic were athleisure and western wear. Due to various factors, there has been a transition in apparel shopping from offline to online platforms. The study has concluded that the pandemic significantly affected consumer behavior in the Indian apparel industry.


In this article, we study the 1 + 3 dimensional relativistic Euler equations on a pre-specified conformally flat expanding spacetime background with spatial slices that are diffeomorphic to R3. We assume that the fluid verifies the equation of state p = csρ, where 0 ≤ cs ≤ √ 1/3 is the speed of sound. We also assume that the inverse of the scale factor associated to the expanding spacetime metric verifies a cs−dependent time-integrability condition. Under these assumptions, we use the vectorfield energy method to prove that an explicit family of physically motivated, spatially homogeneous, and spatially isotropic fluid solutions is globally future-stable under small perturbations of their initial conditions. The explicit solutions corresponding to each scale factor are analogs of the well-known spatially flat Friedmann-LemâıtreRobertson-Walker family. Our nonlinear analysis, which exploits dissipative terms generated by the expansion, shows that the perturbed solutions exist for all future times and remain close to the explicit solutions. This work is an extension of previous results, which showed that an analogous stability result holds when the spacetime is exponentially expanding. In the case of the radiation equation of state p = (1/3)ρ, we also show that if the time-integrability condition for the inverse of the scale factor fails to hold, then the explicit fluid solutions are unstable. More precisely, we show that arbitrarily small smooth perturbations of the explicit solutions' initial conditions can launch perturbed solutions that form shocks in finite time. The shock formation proof is based on the conformal invariance of the relativistic Euler equations when cs = 1/3, which allows for a reduction to a well-known result of Christodoulou.


The post-buckling behavior of the seismic-resistant braces in braced frames under cyclic axial force is often evaluated by time-history analyses; however, they seldom consider brace fracture. Authors have proposed an easy evaluation method predicting the fracture point of the circular and H-section braces after buckling, using macro-models. However, the method is confirmed only against the test results of gradually increased amplitudes and applicability under other loading histories is not verified yet. In this paper, cyclic loading tests on the circular and H-section braces under various loading histories are carried out, and FEM analyses following the test results are performed. Reflecting these results, the validities of the proposed methods for the brace fracture prediction under various loading histories are discussed.


Low temperature tolerance in invertebrates is complex, and is compounded by a great diversity of response to cold temperatures even within a single taxon such as the insects. Invertebrates inhabit a very wide range of terrestrial environments, in which the physical conditions may fluctuate both daily and over a longer time span, and hence their response to a single physical variable such as temperature is far from uniform. Block (1990) emphasized the need to distinguish between the responses of insects to temperatures just above 0'C (non-freezing) and sub-zero temperatures (potentially freezing). This paper is concerned with the latter suite of responses. Ecophysiologists have attempted to synthesize information on low temperature tolerance of invertebrates, particularly for arthropods. For example, from the ecological perspective this has been attempted by Downes (1964), Danks (1978), Bale (1989) and S0mme (1989), whilst Baust & Rojas (1985), Zachariassen (1985), Cannon & Block (1988), and Storey & Storey (1988, 1989) have incorporated a physiological-biochemical approach. There is not, at present, a universally accepted theory of cold tolerance applicable to invertebrates generally, but several recent developments suggest that a, reassessment is timely. In this paper one particular aspect of low temperature tolerance is highlighted; if an invertebrate can tolerate and survive the effects of freezing. The phenomena of freezing tolerance and intolerance are briefly discussed together with their perceived advantages and disadvantages. The question of switching from one to the other is addressed and proposals are made for future experimental work to resolve some of the outstanding problems.


[Objective]To analyze the result of HIV antibody detection by HIV screening lab in Huairou CDC of Beijing from 2005-2010,provide a scientific basis for AIDS prevention.[Methods]The detection of HIV antibody in serum was conducted in high-risk population by the ELISA.[Results]During 2005-2010,10 807 people of high-risk population in Huairou District of Beijing were detected,and the positive rate of HIV antibody was 0.17%.The positive rate in men who have sex with men(MSM) was the highest(6.94%).The difference in positive rate among five high-risk groups(unlicensed prostitutes,prisoner,MSM,STDs clients and voluntary counseling) was significant(χ2=328.24,P0.01).83.33% of HIV-positive people were young people aged 20-39 years old.[Conclusion]Among high-risk population in Huairou District of Beijing,the positive detection rate of HIV antibody in MSM group is the highest.The young people have the high incidence of AIDS,which the key of AIDS prevention and control.


Introduction Lumbar interbody fusion with cage devices has become a routine procedure with a high rate of clinical success after short-term follow-up. The main goals of interbody cages are to correct spinal deformations and to provide primary stability to the spinal segment until interbody fusion is obtained. It is unknown, however, how the process of spinal fusion evolves, and when fusion is actually achieved. It is even more difficult to establish the mechanical quality of a succesful arthrodesis. The aim of a cage device is to create an optimal environment for fusion. Design and material play a pivotal role in this. Mechanical stability of the fused segment is mainly determined by the design and size of the cage [1,2], though not by its orientation [3,4]. The material of the cage, however, is the main determinant of mechanical loading of the bone graft and consequently of the spinal fusion rate, because cage stiffness is the single most important factor for stress shielding [5,6]. It is likely that, even if fusion is achieved in a titanium cage, it is inferior to a fusion that would be obtained in a cage made of less stiff material. In an animal study with three years follow-up, we histologically and histomorphometrically described the development of spinal fusion in time, and found the deteriorating effect of cage stiffness on spinal fusion [6,7]. Out of this three-years study, we obtained some bone samples from the fusion zone for further analysis with micro-CT. Purpose of this analysis was to describe the architectural changes of the fusing bone material in time, and to study the effect of cage stiffness on the bone architecture within the cage.


The prevalence of large volumes and varieties of accessible data is profoundly changing the way business, government and individuals approach decision making. Organizational big data investment strategies regarding what data to collect, clean, integrate, and analyze are typically driven by some notion of perceived value. However, the value of the data is inescapably tied to the underlying quality of the data. Although for big data, value and quality may be correlated, they are conceptually different. For example, a complete and accurate list of the books read on April 1, 2016 by the special editors of this issue may not have much value to anyone else. Whereas even partially complete and somewhat noisy GPS data from public transport vehicles may have a high perceived value for transport engineers and urban planners. In spite of significant advances in storage and compute capabilities, the time to value in big data projects often remains unacceptable due to the quality of the underlying data. Poor data quality is being termed as the dark side of big data, inhibiting the effective use of data to discover trusted insights and foresights. Finding the nexus of use and quality is a multifaceted problem encompassing organizational and computational challenges. These challenges are often specific to the type of data (e.g. the actual use of the data. Designing a practical strategy for tackling quality issues in big data requires data scientists to bring together these multiple aspects of data type, quality dimension and process within the context of their application setting. In this special issue we have endeavoured to present recent research of some of the leading experts in the field of data quality with the aim of informing the design of such practical strategies. Out of the eight papers, four are on relational/structured data while the remaining four are on time series data, spatio-temporal data, micro-blog data and web data. The papers have targeted a number of data quality dimensions through a range of innovative approaches as outlined below. The first two papers tackle data quality dimensions of meta-data compliance and schema quality. Sebas-tian Kruse, Thorsten Papenbrock, Hazar Harmouch, and Felix Naumann present data anamnesis as a means of meta-data discovery with an aim to assess the quality and utility of the underlying relational datasets. In the second paper, Henning Kohler, Sebastian Link and Xiaofang Zhou present a method for discovering meaningful certain keys, in the presence of incomplete …


In the world of music, a variety of digital symbolic music representations exist, from performance oriented (e.g. MIDI) to score oriented (e.g. MusicXML). Contrary to this, in the related world of dance, while a paper friendly symbolic representation exists and is widely adopted (Labanotation or Kinetography Laban), a similar digital open standard has not yet been created. While there have been a few attempts so far, they have focused on encoding types, which require loading of all data before execution, as well as encoding more data than is necessary. Our goal is to create a format that can allow real-time encoding, decoding and interpretation of Labanotation. In the paper, we describe the format, its inner workings and ways of encoding and decoding various


PART I: AMERICAN PUBLIC DIPLOMACY TODAY The Case for Soft Power W.A.Rugh How We Got Here N.J.Cull Lessons of Alhurra Television S.Powers & A.El Gody PART II: FROM THE OUTSIDE: APPRAISING AMERICAN PUBLIC DIPLOMACY The View from Russia V.Orlova The View from China G.Shen The View from Egypt H.Amin PART III: WHERE WE GO FROM HERE Public Diplomacy 2.0 A.Arsenault Privatized Public Diplomacy K.Fitzpatrick A Cultural Public Diplomacy Strategy N.Rosendorf Public Diplomacy in an Age of Faith J.A.Marshall & T.F.Farr The U.S. Military and Public Diplomacy A.Williams The Task for Policymakers P.Seib


Summary form only given. Topology transparent scheduling for medium access control is an attractive technique for mobile ad hoc networks (MANETs) and sensor networks. The transmission schedule for each node is fixed and guarantees a bounded delay independent of which nodes are its neighbours, as long as the network is not too dense. Constructions of and performance criteria for topology transparent schedules have been extensively studied however, to date, frame synchronization is assumed. Synchronization is a difficult problem for MANETs and sensor networks. We study the relationships among topology transparent schedules, synchronization, and maximum delay. Frame synchronization, slot synchronization, and asynchronous transmission are the three synchronization models for this study. For each synchronization model, the first question is: (1) Do topology transparent schedules exist? If the answer to this question is yes, then two further questions are natural: (2) How to construct topology transparent schedules? (3) What is the least maximum delay? For frame and slot synchronization these three questions are answered in earlier work. We give answers for these three basic questions for asynchronous networks.


In this paper, the flaws existed in the original processing flow and machinery of flotation are pointed, the machinery in new system and their characteristics have been inducted, the technical indexes and economic benefit before and after improvement are compared. After remoulding, the ability add 50% and the rate of recovery rise up 8.5%, the target of expanding ability and technical remoulding has been achieved.


Providing game information via character in a game envi ronment comprises monitoring a position of a character in the game environment, providing visual information to the user based on the position of the character in the game environment, the visual information being presented as a modification of the character, and providing audio informa tion to the user based on the position of the character in the game environment, the audio information being presented as Statements from another character. A Visual information module Visually provides game information to the user within the context of the game environment and an audio information module audibly provides game information to the user within the context of the game environment.


This study investigates the attitudes of small business owners/managers toward computers and how computers are used in small businesses. A survey of 236 firms revealed that a majority of the respondents are currently using computers. In general, owners/managers have a positive attitude toward computers. Respondents who have taken a computer class, own a microcomputer, or whose businesses are using computers have a more positive attitude toward computers. The most frequent business computer applications were accounting, mailing lists, and storing information. The most frequently reported personal applications were word processing, accounting, and budgeting. Implications for further computerization of small businesses are discussed.


A 10 watt, infrared, CO2 gas laser providing precisely controlled, highly localized heating has heen used to create thermal bonds between crossed polypropylene monofilaments. Scanning electron micrographs of the bond interface after bond destruction have shown that the bond failed cohesively in the surface layers of the two fiber. The bonding technique will be used in an extensive study of the factors controlling the formation of proper bonds.


presentation is as thoughtfully lucid and the prose so graceful. The volume is physically handsome, with good quality paper and typeset that is easy on the eye. I warmly recommend it to the student on the threshold of a serious study of Markovian stochastic processes and their applications, to the instructor looking for a well-motivated graduate text, and to the connoisseur interested in adding to his library a literate and expert treatment of his subject.


Diffusion of a language personality's communicative presence in virtual reality can be determined as one of the basic characteristics of Internet-discourse. That's the reason why certain elements of expressiveness, imagery, attractiveness and visualization play an important role in cyberspace. To overcome this insufficiency participants in e-discourse stick to the speech strategy of fascination which is to influence the sphere of emotional perception and processing of information on an addressee's level. The speech strategy under consideration is actualized in cyberspace by means of the tactics as follows: emphasal, silencial and those of metaphorisation, exemplification and syllepsis; each of them having their own typical language markers.


Objective: To investigate the effect of butyrate, a by-product of dietary fiber fermented in the colon, on the proliferation and differentiation of human colon cancer cell line SW1116. Methods: Subcultures of cell line SW1116 were maintained in mediums without or with different concentration of butyrate (2, 3, 4, 7 and 10 mmol/L).The cell proliferation rate was measured by MTT and expression of CEA and ALP were detected after 6, 24, 48 and 72 h. The cell phenotype was observed by electronic microscope. Results: The inhibition of SW1116 cell growth and proliferation by butyrate were dose-dependent, with a highest rate of 53.9% observed with the limits of the study. Butyrate could significantly increase the expression of CEA and ALP in the SW1116 cell line with a manifest dose-time effect, their expression reached the peak level when the butyrate concentration ≥ 7mmol/L and culture time≥48h (P0.001). The microvilli in the cell surface increased also after butyrate treatment. Conclusions: Butyrate can inhibit the proliferation of colon cancer cell line SW1116 and induce its differentiation.


In geographical areas subject to an arid climate, one of the most precious resources is water, which often get wasted due to inefficient irrigation systems. Automated irrigation systems which relies on closed loop control and feedback from sensors can help to closely match the water supply to the crop demand and avoid waste. In recent years, predictive control strategies were proposed for high tech watering systems which rely heavily on complex models incorporating variables such as crop water demand, soil evapotranspiration, weather conditions etc.. Through these models it is possible to anticipate the water demand of the crop, and give optimal irrigation scheduling with a significant reduction in water consumption. In this paper we developed a model of the soil moisture dynamics based on climatological data of the Kingdom of Bahrain. The model, which is based on the hydraulic balance approach, was validated by comparing its estimated output with real measurements.


In children Cushing's disease is rare. Growth prognosis, adequacy of development of peak bone mass, development of metabolic complications of the disease all depend on timeliness of diagnosis and treatment. Presented in this article are contemporary data on peculiarities of clinical picture, diagnosis and treatment of Cushing's disease in childhood.


The study of intertextuality, or how authors make artistic use of other texts in their works, has a long tradition, and has in recent years benefited from a variety of applications of digital methods. This article describes an approach for detecting the sorts of intertexts that literary scholars have found most meaningful, as embodied in the free Tesserae website . Tests of Tesserae Versions 1 and 2 showed that word-level n-gram matching could recall a majority of parallels identified by scholarly commentators in a benchmark set. But these versions lacked precision, so that the meaningful parallels could be found only among long lists of those that were not meaningful. The Version 3 search described here adds a second stage scoring system that sorts the found parallels by a formula accounting for word frequency and phrase density. Testing against a benchmark set of intertexts in Latin epic poetry shows that the scoring system overall succeeds in ranking parallels of greater significance more highly, allowing site users to find meaningful parallels more quickly. Users can also choose to adjust both recall and precision by focusing only on results above given score levels. As a theoretical matter, these tests establish that lemma identity, word frequency, and phrase density are important constituents of what make a phrase parallel a meaningful intertext.


The p-type conducting hydrogen-terminated diamond obtained from hydrogen plasma has several applications in the field of power semiconductor devices. Therefore, clarifying the effects and role of hydrogen plasma on diamond surfaces is a critical aspect in the field of hydrogen-terminated diamond devices. In this study, we focused on diamond surface etching by hydrogen plasma and revealed the dependence of the diamond crystal orientation using scanning probe microscopy and electron backscatter diffraction. Crystal grains with a low etching rate were distributed around the {100} and {111} planes, and those with a high etching rate were distributed on the {110} plane. Furthermore, we found that the etching rate increased as the intermediate orientation grains tilted toward the {110} plane. Because the surface carbon atoms that compose the {110} plane have two of their three back bonds on the surface exposed to hydrogen plasma, we expected that the {110} orientation would have a high etching rate. Even for grains with intermediate orientations, the etching tendency corresponded to the location of the back bonds. Our research provides important systematic data on the crystal orientation in diamond electronics.


The present invention is a warm-blooded animal, especially a human brain, in a non-invasive method, relates instrument (1) for selectively cooling, the instrument, cooled activatable self-contained cooling a source means (4,18,19), and a mounting means for attaching to a warm-blooded animal head / neck. An object of the present invention, the warm-blooded animal brain temperature, without the need for medical personnel skilled in especially, more quickly, as more efficiently can be reduced, the effect is obtained that, the aforementioned it is to improve the instrument. This object is appliance as heat conduction path (9,15,16) is formed between the cooling source means and (4,18,19) and a warm-blooded animal at least one of the carotid artery (1) the is accomplished by configuring the attachment means so that it can be attached to a warm-blooded animal. .FIELD 1


The task of developing the Sistem pendaftaran Dan Temujanji Jabatan Pengimejan Diagnostik Hospital Tengku Ampuan Afzan Kuantan (HTAA) is a process of automating all manual processes of the current available system. The manual system used currently involves transaction processes such as patient registration, X-ray film filing and several periodical reports such as reject film analysis and total X-rays done for the month. The Rapid Application Development (RAD) methodology was chosen to facilitate the process of system development. The Client - Server architecture which was adopted for this system will make encourage resource sharing and thus minimize the overall operation cost. Essentially the main objective of the development of the system is to see to the needs of the management to spruce up the managerial duties of the organization. This is in line of the objective of HTAA and Jabatan Pengimejan Diagnostik itself. It is a hope that with the completion of the system, Jabatan Pengimejan Diagnostik HTAA Kuantan will be in a better position to serve the needs of the people.


Abstract A physical mechanism of Na channels in the excitable membranes based on the ferroelectric phason model is proposed. Such model is a development of the ellipsoidal phason concepts in ferroelectrics.


Abstract:Drawing on collaborative inquiries with four elementary teachers in the United States who intentionally incorporated diverse picturebooks into their teaching, the following article reveals the potential for cultivating social imagination and creating space for agency and activism. The importance of picturebooks for today's readers is emphasized to attune not only to the beauty in the world but also to relationships to others and responsibilities in light of social inequalities.


The photocycloaddition of alkyl phenylglyoxylates to allylic alcohols leads to oxetanes 3a–h with high to moderate (2R∗,4R∗)-diastereoselectivity that can be easily ring-opened to give 3-hydroxyfuran-2(3H)-ones 4a–b.


Volatile compounds in "Okubao" peach(Prunus persica(L.) Batsch cv."Okubao")during postharvest storage at 8 ℃ were investigated using SPME-GC/MS.The organoleptic qualities of the aroma and off-flavor were evaluated.Relationships between sensory attributes and the volatile composition of peach were analyzed by using partial least squares regression(PLSR).The results showed that 1-MCP reduced the aroma quality of peach fruit.γ-decalactone and δ-octalactone,the characteristic aroma compounds in peach,were correlated positively with aroma and negatively with off-flavor and the increase of their contents could promote aroma quality.In contrast,2-fluoro-acetamide and propanoic acid-2,2-dimethyl-2,6-bis(1,1-dimethylethyl)-4-methylphenyl ester significantly inhibited aroma quality.Besides,Diisobutyl succinate and 1-phenyl-1,3,3-trimethylindan were correlated positively with aroma,while acenaphthene and cyano acetic acid correlated positively with off-flavor.


A novel dielectric resonator filter withtruncated cylindrical cavity isproposed inorder torealize dualmodenarrowbandfilters without tuning andcoupling elements. A fullelectromagnetic optimization method using thethree dimensional fmite element method permits rigorous prediction ofatwopolefilter. A representative prototype ofdualmodedielectric resonator filter using truncated metallic cavity isbuilt andtested. Thefavorable comparison between experimental and theoretical results validates ourcoupling technique andtheaccuracy ofourcomputations. Atlast, thedesign ofanelliptic four poledualmodeDR filter withtruncated cavities andoriginal tuning iris is-proposed.


Hoffman et al. (1) reported lower outflow of MSN A at rest in young IDDM patients (who had no evidence of autonomic neuropathy detectable by sensitive cardiac testing) than in agematched nondiabetic control subjects. They found normal MSNA responses to a cold pressor test and to euglycemic insulin infusion in the patients. They interpreted the lower level of MSNA at rest to be an early manifestation of diabetic autonomic neuropathy. An alternative, and more likely in my opinion, interpretation is that the difference was attributable to physiological variation between the groups. With the first recordings of MSNA, pronounced interindividual variation was discovered (2). As a consequence, both a risk of missing true differences between groups and a risk of finding differences that are nonetheless random do exist. It is, indeed, possible to randomly select control groups that differ significantly in this regard. In a recent study of 16 healthy subjects, we tested 8 with a glucose load and 8 with a protein meal. Mean ± SE MSNA at rest, in the fasting state, was 21 ± 2 bursts/min in one group and 12 ± 2 bursts/min in the other (P= 0.014). No differences were noted in age, blood pressure, or glucose or insulin levels, as in the study of Hoffman et al. Hoffman et al. quoted my earlier paper on MSNA in patients with diabetes (3). Parenthetically, the type and duration of diabetes was, in fact, stated, and MSNA was recorded in 5 of 8 patients without neuropathy and 4 of 15 patients with neuropathy. In that report, I made no mention of the level of MSNA activity, i.e., the number of bursts/min, because I did not consider that meaningful in view of the normal interindividual variation. However, high levels of MSNA were observed in some IDDM patients with overt autonomic neuropathy. An example is shown in Fig. 1, which shows the mean voltage neurogram from a


An online marketing campaign using smart search engine optimisation strategies can help law firms win business, but there are some rules to consider.


In this study we developed a new method for minicolumnar identification in brain images. We measure width of minicolumns by using myelinated bundles of axons. Using recursive spectral segmentation by Otsu thresholding we separate different parts of neocoretex and extract myelinated bundles. By tracing lines perpendicular to them we measure minicolumnar width. We also measure macrocolumnar width by minicolumnar clusters


A predictive model of field hydraulic conductivity of compacted cement kiln dust treated black cotton soil as landfill liners was under taken using FORTRAN-based First-Order Reliability Method (FORM). Reliability estimates of hydraulic conductivity was developed from data obtained from laboratory results for specimens compacted at the energy levels of British standard light (BSL) and West African standard (WAS) British standard heavy (BSH). Statistical analyses were carried out on data using Mini-tab R15 statistical software. Statistical Results obtained were incorporated into a FORM program and safety index values obtained. Generally, only BSH compactive effort produced satisfactory safety index value of 1.0 as specified for serviceability limit state design for hydraulic conductivity. Compositional factor such as water content relative to optimum failed to produced acceptable safety index value of 1.0 at the energy levels of BSL, WAS and BSH compactive efforts for coefficient of variation (COV) ranges of 10-100%. Observed trends indicate that the degree of saturation, plasticity Index, cement kiln dust content and percentage fines are greatly influenced by the COV and therefore must be strictly controlled in cement kiln dust-black cotton soil mixtures for use in covers and liners in waste containment facilities. Stochastically, only BSH compactive efforts can be used to model the hydraulic conductivity behavior of cement kiln dust treated black cotton soil for landfill liners at the variable ranges of 0-80% COV. Finally, care must be taken in ensuring that the compactive efforts required to produce successful safety index are carefully monitored during the construction of liners and covers in waste containment facilities.


For the linear discrete stochastic descriptor systems with multisensor, using the singular value decomposition, it is transformed into two reduced order subsystems, and a new fusion method of constructing the original state fuser based on the transformed state fuser is presented. Using Kalman filtering method, under the linear minimum variance optimal weighted criterion by matrices, diagonal matrices, and scalars, three optimal weighted fusion reduced order descriptor Kalman estimators are presented respectively. They can handle the fused filtering, smoothing, and prediction problems in a unified framework. They can reduce the computational burden, and can improve the local filtering accuracy. The accuracy relations among three fusers and local estimators are proved. In order to compute the optimal weights, the formula of computing the covariance matrices among local filtering errors is presented. A Monte Carlo simulation example shows its effectiveness.


The development objective of the Rural Water Supply and Sanitation Project for Tajikistan is to improve the current situation in the water supply and sanitation sector, with the focus on three rural areas in Khatlon region. Some of the negative impacts and mitigation measures include: (1) replacement with equivalent or more agricultural advantageous land. Transfer of any land to project affected persons (PAP) shall be free of taxes, registration, and other costs; (2) assistance in rental and lease of alternative land; (3) cash compensation equivalent to local average of 6 months' salary; (4) opportunity cost compensation equivalent to 5 percent of net annual income based on tax records for previous year; and (5) cash compensation for any assets affected (for example, boundary wall demolished, trees removed).


A series of novel benzimidazolium bromides containing bulky 3,5-di-tert-butyl group were synthesized in high yields as N-heterocyclic carbene (NHC) ligands. These NHC ligands were metallated with Ag2O under moderate conditions to give novel silver–NHC complexes. The structures of all compounds were characterized using 1H NMR, 13CNMR, infrared and elemental analysis techniques, which supported the proposed structures. The silver–NHC complexes were screened for their in vitro antimicrobial activities against the standard bacterial strains Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa and the fungal strains Candida albicans and C. tropicalis. The results showed that most of the silver–NHC complexes inhibited the growth of all bacterial strains and fungal strains and were found to display effective antimicrobial activity against different microorganisms.


In the complex world of business-to-business (B2B) marketing, three varieties of stakeholder have great influence on company reputation and revenue growth: media, analysts, and consultants. The last of these publics is the least understood and least systematically cultivated. The first three parts of this article look at who the major management and technology consultants are, what they do, and why they matter to B2B corporations as a source of direct and leveraged business. The fourth section explores organizational options as well as the most effective strategies and tactics for managing relations with consultants. The fifth section focuses on the soft and hard results of a consultant relations (CR) program that need to be examined in order to evaluate its true effectiveness; and the last section, "a postscript," investigates the sea-change that has occurred in the top-tier consultant community in the years since scandal brought down both Enron and Andersen in 2001.


A 33‐year‐old woman had a metastasizing leiomyoma in which mitotic figures could not be found. The tumor was composed of well differentiated smooth muscle indistinguishable from uterine leiomyoma or normal myometrium by light and electron microscopy. The S‐phase fraction of the tumor, measured by in vitro tritiated thymidine labeling, was near the upper limit of the range seen in seven ordinary uterine leiomyomas and was distinctly lower than that in a uterine leiomyosarcoma. The content of estrogen receptors in the cytosol was within the range seen in uterine leiomyomas. Metastasizing leiomyoma is an actively proliferating neoplasm of mature smooth muscle that appears to be hormonally responsive. The tumor in our patient showed no clear differences from ordinary leiomyomas in findings relating to the rate of cellular proliferation, morphology, or estrogen receptor content.


Improvisation is a fundamental aspect of musicianship and an important pursuit in music education. Children in music classes throughout the world are engaged with improvisation in a variety of modes and settings. Whether singing, physically moving, or playing an instrument, the act of improvising in front of others may raise one's self-consciousness, potentially leading to feelings of fear and anxiety. We wish to share guiding principles for improvisation to alleviate many of the associated fears. The establishment of a classroom improvisation culture may breed willful participation and acceptance. When willful participation and acceptance become habitual, the goal of establishing a safe space for students to explore their musical creativity is more readily achieved. A manifestation of the guiding principles is shared in the form of two model improvisation experiences for the general music classroom.


In response to this call, a joint Workshop was organised at short notice, bringing together international experts from Russia, the NATO countries and other relevant nations to discuss the social and psychological implications of the new terrorism. The workshop was held at NATO Headquarters between the 25 and 27th March 2002, and generated interest, activity, enthusiasm and no shortage of questions that need to be addressed.


Furosemide (FD) and spironolactone (SP) were co-administrated to human volunteers, and the pharmacokinetics and time course of diuresis were examined. The time courses of FD plasma concentration and diuresis after a single co-administration of FD plain tablet and SP were similar to those in the case of FD plain tablet. However, the plasma concentration of SP metabolites (determined as canrenone) during the 2-6 h period after a single co-administration of FD plain tablet and SP was about 0.05-0.15μg/ml higher than that after administration of SP. The steady-state distribution volume of SP metabolites after co-administration of FD plain tablet and SP was about 30% less than that after administration of SP, while the elimination rate constant of SP metabolites was about 1.5-fold greater. The diuresis during 24 h after a single administration of SP was 0.1-0.31.After multiple administration of SP, the plasma concentration of SP metabolites during the 2-6 h period after co-administration of FD plain tablet and SP was also about 0.1-0.3μg/ml higher than expected from the time course of SP metabolites simulated by using the data obtained after a single administration of SP. The elevation of SP metabolites concentration in plasma was prevented without any change of diuresis over 24 h by using FD retard capsule instead of FD plain tablet.We concluded that the phenomenon of elevation of SP metabolites concentration in plasma was caused by FD plain tablet, which induced strong diuresis and considerable loss of body fluids within a short time.


Kashgar is the most amorous feelings of the Islamic cities in west China,through field investigation,it preliminary introduced the Kashgar Islam style of classical garden landscape on behalf of the Apak Hojia Mausoleum,High Platform Folk Houses,and modern garden examples of the People Park and the East Lake Park.


A kind of combinatorial map, called arrow presentation, is proposed to encode the data of the oriented closed surface complex Sigma on which the Hopf algebraic Kitaev model lives. We develop a theory of arrow presentations which underlines the role of the dual of the double of Sigma as being the Schreier coset graph of the arrow presentation, explains the ribbon structure behind curves on D(Sigma)* and facilitates computation of holonomy with values in the algebra of the Kitaev model. In this way we can prove ribbon operator identities for arbitrary f.d. C*-Hopf algebras and arbitrary oriented closed surface complexes. By means of a combinatorial notion of homotopy designed specially for ribbon curves we can rigorously formulate"topological invariance"of states created by ribbon operators.


Sound recorded from beehives is important to understand a colony's state. This fact is used in the we4bee project, where beehives are equipped with sensors (among them microphones), distributed to educational institutions and set up to record colony characteristics at the communication level. Due to data protection laws, we have to ensure that no human is recorded besides the bees' sound. However, detecting the presence of speech is challenging since the frequencies of human speech and the humming of bees largely overlap. Despite having access to only a limited amount of labeled data, in this initial study we show how to solve this problem using Siamese networks. We find that using common convolutional neural networks in a Siamese setting can strongly improve the ability to detect human speech in recordings obtained from beehives. By adding train-time augmentation techniques, we are able to reach a recall of up to 100%, resulting in a reliable technique adhering to privacy regulations. Our results are useful for research projects that require written permits for acquiring data, which impedes the collection of samples. Further, all steps, including pre-processing, are calculated on the GPU, and can be used in an end-to-end pipeline, which allows for quick prototyping.


The purpose of the article is to identify the features of the course of action and the results of the Agasher war between Mali and Burkina Faso in 1985. The author outlined the causes of the Agasher war between the Republic of Mali and the Republic of Burkina Faso in 1985 based on research methods such as observation and comparison. The author analyzes the intentions of the parties, gives a comparative characteristic of the forces and means used by the opponents. As a result of the research, the authors evaluates the effectiveness of the forms and methods of military operations used during the conflict, presents the military-political results of the conflict and examines post-conflict settlement activities.


EDUCATORS and psychologists have long espoused the ideal of tailoring instruction to provide for individual differences in children. In fact, special education was established to relieve the burden of regular classroom teachers who found it difficult to individualize instruction for handicapped children. It was then presumed best for instructional purposes to group certain children into categories, on the assumption that they could learn better when homogeneous teaching methods and materials were used. More recently, psychoeducational evaluation directed toward differential assessment of abilities and specific programing based on the results of that assessment (diagnostic-prescriptive teaching) has become prominent. Although diagnostic-prescriptive teaching has been hailed by Barbara Bateman as "the new scientific pedagogy," Lester Mann has severely criticized this approach, stating that he is "vehemently opposed to present conceptualizations of abilities as processes that can be identified precisely by existing tests for training purposes." In 1972 the senior author reviewed the present state of diagnostic-prescriptive teaching and concluded that there is little empirical support for the diagnostic-prescriptive model-primarily because most research efforts have been inadequately designed to test it? Rather, support for this model has generally come from correlational studies and gain-score research. (The methodo-


capture all of the multitude of common laws he identifies in his expansive definition do not hold up to scrutiny. While the ius commune was a relational, gap-filling law in the sense that the ius propria came higher in the hierarchy of sources, the gaps the Roman law was called upon to fill were huge and frequently overshadowed the local positive law. In England, while the common law accommodated local custom, the divide was jurisdictional. Reversing the relational pattern of the ius commune, the English common law took precedence in the king's courts and left the local courts to apply local law. Pairing "gap-filling" and "non-binding" in the definition creates its own problems. If the common law served as a gap-filler, then at a certain point its contents were employed as rules of decision, and presumably became binding in some sense. When this happened, did the rule derived from the common law become a part of the ius propria (according to Glenn the only type of binding law), and thus no longer part of the common law? Is the common law only what is left after the ius propria has whittled away all the rules it wants, as if the common law were nothing but a source of ideas for the ius propria to raid? In any event, Glenn is not correct to claim that the common laws were non-binding. The law applied in the king's courts in England was most certainly binding, and if at least parts of the ius commune were not considered binding it becomes difficult to explain the widespread citation to Roman law in continental court decisions or the group of early modern works listing those parts of the Roman law abrogated by local customary law. Another important characteristic in Glenn's definition is non-exclusivity. This, he claims, means not only that common laws can coexist with iura propria but also that common laws can coexist with each other in the same territory. However, Glenn does not address the question of where the borrowing of discrete legal concepts ends and the adoption of a secondary common law begins. Many of his examples could perhaps best be explained as evidence of the former rather than of the latter. As a final point, Glenn explicitly uses history normatively. He also uses it cavalierly, eliding historical periods and speaking in generalities so broad that a reader unfamiliar with the history risks being misled and a knowledgeable reader frustrated.


This paper introduces a kind of 10-channel temperature controller-recorder for semiconductor air-conditioners of storage-transport containers. The core-controlled unit is the MCU-AT89C5 . DS1820 digital thermometers are used for temperature sampling and circuit checks. A micro-stylus printer prints values of the each point temperature and the working state timing. The output signal of the MCU through a photo-coupler drives two relays to control the working mode (cooling/heating) and the function state. The controlled program of the MCU is adopted C51 senior language and assembles language. 1-Wire/sup TM/ digital thermometers that predigest the external device and cable of the sensors greatly reduce cost and improve reliability.


In Theatre Is More Beautiful than War, Marvin Carlson sets out to "give some idea of the richness and variety" of the German Regietheater (director's theatre) (xiv). It is no surprise that Carlson—one of the foremost theatre historians of our time—has little difficulty accomplishing this task. In nine immensely readable chapters, he surveys the careers of the Regisseure who have most notably shaped the director-driven theatre that has largely defined the German-speaking stage for the past half century. From Peter Stein's legendary post-1968 experiments with collective theatre, through the irreverent, postdramatic productions Frank Castorf unleashed on reunited Berlin in the 1990s, Carlson's text offers the most sweeping account of the Regietheater available to date in English. Carlson bookends his study with a quick glance at the origins of the Regietheater and a pithy concluding discussion of the sustainability of this rich but expensive approach to theatre making. Carlson cleanly divides his study into three parts of three chapters each. Rather than center on particular movements, periods, or theatres, each chapter focuses on the career of a single director. This structure makes the book a useful reference on contemporary German directors, but also limits the potential for comparing directors or examining the relations between them. Carlson groups directors along ostensible generational lines, presenting Peter Stein, Peter Zadek, and Claus Peymann as "The Old Masters," Andrea Breth, Frank Castorf, and Christoph Marthaler as "The Successors," and Michael Thalheimer, Thomas Ostermeier, and Stefan Pucher as "The Next Generation."While giving some productions considerably more attention than others, Carlson offers a chronological treatment of nearly every director's stagings. The material presented is based both on Carlson's own viewing experiences and (more often) on reviews in newspapers and the journal Theater Heute—Carlson's favored source for this study. This methodology permits Carlson both to outline each director's critical reception throughout his or her respective career, and to identify the distinctive characteristics of his or her respective style. The lack of any principle of exclusion for the productions he discusses, however, leaves Carlson little space for in-depth analyses of particular stagings. For example, he notes that Peter Stein's December 1974 production of Summerfolk "took Stein's work in a new direction" because it involved a turn to realism and psychological motivation (13). We also learn that critics and audiences "widely considered" Summerfolk to be one of Stein's "most powerful and innovative" productions (14). But Carlson presents almost no detail about Stein's direction itself. As a result, readers are left wondering what it was about Summerfolk that led to this "new direction"—and wondering as well precisely how the production was staged. Nevertheless, Carlson's method deftly situates


Through numerical simulations and model tests,the hydrodynamic properties of a HOV are studied when approaching sea bottom structure.The feasibility of the numerical simulations is demonstrated by model test results,and the variations of the HOV hydrodynamic property are analyzed carefully after that.These research results are very helpful in optimization design of submersible,and could also be references of the multi-body submersible design and the cooperative work of submersibles.


A low-emittance, high-intensity atomic beam of muonium ($\mathrm{M}=\mu^+ + \mathrm{e}^-$) using superfluid helium as muon-to-muonium converter is being developed at the Paul Scherrer Institute (PSI). This beam could advance laser spectroscopy of muonium and allow the first atomic interferometry experiments for the direct observation of the M gravitational interaction. In this paper, we describe the development of compact detection schemes which resulted in the background-suppressed observation of atomic muonium in vacuum, and can be adapted for cryogenic measurements. Using these setups, we compared the emission characteristics of various muonium production targets using low momentum ($p_{\mu} = 11$-$13~$MeV/c) muons, and observed muonium emission from zeolite targets into vacuum for the first time. For a specific laser-ablated aerogel target, we determined a muon-to-vacuum-muonium conversion efficiency of $7.23 \pm 0.05 \text{(stat)} ^{+1.06}_{-0.76}\text{(sys)}\,\text{%}$, assuming thermal emission of muonium. Moreover, we investigated muonium-helium collisions and from it we determined an upper temperature limit of 0.3 K for the superfluid helium converter.


The lattice gauge theory (LGT) for curved spacetime is formulated. A discretized action is derived for both gluon and quark fields which reduces to the generally covariant form in the continuum limit. Using the Wilson action, it is shown analytically that for a general curved spacetime background, two propagating gluons are always color-confined. The fermion-doubling problem is discussed in the specific case of Friedman–Robertson–Walker (FRW) metric. Last, we discussed possible future numerical implementation of lattice QCD in curved spacetime.


1. The following report is not a syllabus of arithmetical teaching, far less a formal treatise, but an attempt to reduce to some order the miscellaneous suggestions at the disposal of the committee.* These suggestions are roughly classified into seven groups. Arithmetic includes both a science and an art, or a theory and applications of it to the wants of life. Of the seven divisions in this report the first four have mainly to do with the art, the next two with the science of arithmetic (the division is not observed with thoroughgoing strictness), while the seventh division contains a few general hints for teaching. These divisions may be briefly styled :—


Construction industry relies heavily on conventional material such as cement, sand and gravel for the production of concrete The river sand and gravels which are most commonly used as fine aggregates and coarse aggregates respectively in the production of concrete, poses the problem of acute shortage in many areas, whose continued use has started posing serious problem with respect to its availability, cost and environmental impact. Attempt is being made in this project to use the locally available waste materials to replace the river sand and gravels to produce light weight and low cost concrete. Sawdust and Brick ballast are easily affordable at low costs, which are partially replaces with river sand and gravels respectively for making concrete. Natural sand and Gravels have been partially replaced (4% SD 8% BB, 4% SD 16% BB, 4% SD 24% BB, 8% SD 8% BB, 8% SD 16% BB, 8% SD 24% BB, 12% SD 8% BB, 12% SD 16% BB and 12% SD 24% BB. by using M30 grade of concrete) with sawdust and broken brick ballast respectively. For this, thirty concrete cubes of size 150mm X 150mm X 150mm have been casted and water cement ratio of 0.42 has been used. Water reducing admixture is used to increase the workability. Slump test, Compacting factor test and compressive strength at (28 days) of specimens having above combinations have been compared with control specimens. The workability and compressive strength gradually decreases for the increasing the replacement percentages. The optimum mix found to produce M30 grade of concrete is 8% of sawdust and 16% of Brick ballast Neeru Singla1, Mandeep Kumar2 12IGKPTU, Jalandhar, Punjab, India. E-mail: firstname.lastname@example.com Published Online: 28 December, 2017 The Author(s) 2017. This article is published with open access at www.chitkara.edu.in/publications Journal on Today's Ideas – Tomorrow's Technologies, Vol. 5, No. 2, December 2017 pp. 112-122 INTRODUCTION As the time is passing, due to the development of infrastructure the construction industry is growing at a vast rate. Concrete is a mixture of cement, fine aggregates, coarse aggregates and water. Normally river sand is used as fine aggregates and stones or gravels are used as coarse aggregates in the concrete. These materials are limited on the earth. To overcome this type of problem researcher found substitute materials for aggregates. There are many types of waste materials available in our environment, which can be replaced with aggregates in concrete for making concrete. These waste light weight materials https://doi.org/10.15415/jotitt.2017.52007


Renewable energy is becoming a prosperous industry with numerous researchers focusing and exploring new and effective ways to harness the power from means available on spot. This paper presents a new proposed mechanism for harnessing from vehicles passing over ramps energy destined of going into waste if not harvested. It is kinetic energy used for generating electricity. Unlike the many other designs for power generation, this paper sheds light on the idea of the rotational conversion-using flywheel and gear mechanism used underneath the road surface at the point of road where a speed-breaker is raised. The linear motion of a rack is converted into rotational motion applied by the oncoming vehicular load. The system is described in terms of the dimensions of the rack and pinion and the number of teeth on the gears. The pulley structure is geared such it is ultimately making a generator to rotate for producing an output voltage. The output voltage is of variable nature depending on the traffic flow. The system is described on assumption of single vehicle passing by over a time interval of hence producing a power output as the vehicle is inputting a certain amount of energy in a given time interval. The analysis of the system is in terms of the related equations.


The restructuring of industry and optimized to promote the economic health,Fujian province,Fujian province of the industrial structure with a detailed analysis of very important actual significance.Combination of qualitative and quantitative method for the industrial structure,Fujian province to analyse and review on the basis of Fujian and the industrial structure of the problems of the industrial structure,Fujian province of the basic and important measures.


Explicit knowledge is knowledge that a learner has about a language and that he or she is conscious of and able to report in some way (Ellis, 2008).

Keywords:

esl/efl;
language teaching;
second language acquisition;
grammar


The article contains sections titled:

1. Introduction
1.1. Comparison with Other Spectroscopic Methods
1.2. Development and Uses
2. Theoretical Principles
2.1. Electronic States and Orbitals
2.2. Interaction Between Radiation and Matter
2.2.1. Dispersion
2.2.2. Absorption
2.2.3. Scattering
2.2.4. Reflection
2.2.5. Band Intensity
2.3. The Lambert–BeerLaw
2.3.1. Definitions
2.3.2. Deviations from the Lambert - Beer Law
2.4. Photophysics
2.4.1. Energy Level Diagram
2.4.2. Deactivation Processes
2.4.3. Transition Probability and Fine Structure of the Bands
2.5. Chromophores
2.6. Optical Rotatory Dispersion and Circular Dichroism
2.6.1. Generation of Polarized Radiation
2.6.2. Interaction with Polarized Radiation
2.6.3. Optical Rotatory Dispersion
2.6.4. Circular Dichroism and the Cotton Effect
2.6.5. Magnetooptical Effects
3. Optical Components and Spectrometers
3.1. Principles of Spectrometer Construction
3.1.1. Sequential Measurement of Absorption
3.1.2. Multiplex Methods in Absorption Spectroscopy
3.2. Light Sources
3.2.1. Line Sources
3.2.2. Sources of Continuous Radiation
3.2.3. Lasers
3.3. Selection of Wavelengths
3.3.1. Prism Monochromators
3.3.2. Grating Monochromators
3.3.3. Electro-Acoustic and Opto-Acoustic Wavelength Generation
3.4. Polarizers and Analyzers
3.5. Sample Compartments and Cells
3.5.1. Closed Compartments
3.5.2. Modular Arrangements
3.5.3. Open Compartments
3.6. Detectors
3.7. Optical Paths for Special Measuring Requirements
3.7.1. Fluorescence Measurement
3.7.2. Measuring Equipment for Polarimetry, ORD, and CD
3.7.3. Reflection Measurement
3.7.4. Ellipsometry
3.8. Effect of Equipment Parameters
3.9. Connection to Electronic Systems and Computers
4. Uses of UV - VIS Spectroscopy in Absorption, Fluorescence, and Reflection
4.1. Identification of Substances and Determination of Structures
4.2. Quantitative Analysis
4.2.1. Determination of Concentration by Calibration Curves
4.2.2. Classical Multicomponent Analysis
4.2.3. Multivariate Data Analysis
4.2.4. Use in Chromatography
4.3. Fluorimetry
4.3.1. Inner Filter Effects
4.3.2. Fluorescene and Scattering
4.3.3. Excitation Spectra
4.3.4. Applications
4.4. Reflectometry
4.4.1. Diffuse Reflection
4.4.2. Color Measurement
4.4.3. Regular Reflection
4.4.4. Determination of Film Thickness
4.4.5. Ellipsometry
4.5. Resonance Methods
4.5.1. SurfacePlasmon Resonance
4.5.2. Grating Couplers
4.5.3. Other Evanescent Methods
4.5.4. Interferometric Methods
4.6. On-Line Process Control
4.6.1. Process Analysis
4.6.2. Measurement of Film Thicknesses
4.6.3. Optical Sensors
4.7. Measuring Methods Based on Deviations from the Lambert – Beer Law
5. Special Methods
5.1. Derivative Spectroscopy
5.2. Dual-Wavelength Spectroscopy
5.3. Scattering
5.3.1. Turbidimetry
5.3.2. Nephelometry
5.3.3. Photon Correlation Spectroscopy
5.4. Luminescence, Excitation, and Depolarization Spectroscopy, and Measurement of Lifetimes
5.5. Polarimetry
5.5.1. Sugar Analysis
5.5.2. Cellulose Determination
5.5.3. Stereochemical StructuralAnalysis
5.5.4. Use of Optical Activity Induced by a Magnetic Field
5.6. Photoacoustic Spectroscopy (PAS)


Based on the interation between particles of quantum system and the possible geometric control to be applied,a mathematical model of two spin 1/2 particle system with interaction is built,whose variables are varying in the Lie groups of SU(4).The physical control procedure of the quantum system with interaction is described in detail.This work is a preparation for further research on controllability,manipulation and feedback control of quantum system.


The 21st century's democratization and demonetisation of multimodal learning sources allows anyone to be both consumers and producers at the same time. The present study argues that the consumption and production of independent short films through affordable digital devices as beneficial for multimodal language learning, befitting the student's interest and the building of the six essential skills of their 21st-century context. The present study was designed as library research observing 30 most recommended articles in the related topic by Google Scholar, published in reputable international journal from 2010 to 2020. It is argued that consumption and productions of short films can be used for enhancing the students' language skills. They can be used to tap the students' creativity, communicative skills, critical thinking, and collaborative skills. At the same time, they can also be used to enhance their compassion toward issues around their society and environment during the implementation of procedural and computational thinking in this consumption and productions of short films. These also place the students as the subjects of the learning process, where their views, opinions, and feelings about certain issues matter so they can play their role in making the world a better place to live in.


The sunflower, unlike other phytotechnical plants, tolerates drought much better, this is primarily due to the better developed root system with a high capacity to absorb and solubilize water and nutrients from the soil, for a longer period of time, its ability to reduce evapotranspiration and, respectively, the possibility of a rapid return of the leaves to the state of turgor, but the production decreases proportionally to the intensity and duration of these processes. To achieve high performance, sunflower cultivars must have stable F1 heterosis, high seed oil content, high production capacity, short growing season, uniformity in average plant height, high resistance to agents pathogens. In the ecopedological conditions of the Bărăşti - Olt area, on a preluvosol type soil, research was carried out on a number of 6 hybrids: Favorit, Performer, Venus, Saturn,  Alex, Vera, the production results highlighting their different adaptation to specific culture conditions. The highest yields were recorded for the Performer hybrid -3935 kg/ha and the Venus hybrid -3786 kg/ha. All hybrids achieved productions above 3000 kg/ha.


This study presents a diametric distribution model based on a one-dimensional cellular automata (CA) model and artificial neural network (ANN). Each CA cell proposed stands for a dap class, with the future state being predicted in function of the present state of this cell, the state of its surrounding cells and of its present and future ages. An ANN was used as a rule of evolution. Accuracy was evaluated by applying the statistical procedure L, a relationship between observed and estimated frequency and biological realism of the model built. Of the trained networks, 10 representing diametric distribution evolution with more accuracy were selected. Of these 10 ANR, seven represented estimated values statistically equal to those observed (p>0.01). The focus of the modeling proposed allows estimating future diametric distributions accurately.


A Symbolic t6tnaiysis or ue ay and represent the hindrance of an open circuit. Thus when the circuit a-b is open Xab and when closed Xab = 0. Swi chi, Circuits Two hindrances Xab and Xc will be said to be equal if whenever the circuit a-b is open, the circuit c-d is open, and whenever a-b is closed, c-d is closed. ENROLLED STUDENT AIEE Now let the symbol + (plus) be defined to mean the series connection of the two


Dissections in the life science classroom have become less prevalent as science educators have questioned what these experiences teach. Constructivist theorists of education have long suggested redefining the purpose of dissections to better fit the needs of student learning in the 21st century. Using the Next-Generation Science Standards framework, educators can create more meaningful dissections by incorporating opportunities for students to engage in true scientific inquiry. For dissection experiences to be worthwhile and meaningful for students, the activity must be carefully planned and worked into a unit where students can use such an experience to help answer a central unit question. Innovative 21st century dissection activities that allow students to engage in true scientific inquiry are addressed.


Background:Medicare and private plans are encouraging individuals to seek care at hospitals that are designated as centers of excellence. Few evaluations of such programs have been conducted. This study examines a large national initiative that designated hospitals as centers of excellence for knee and hip replacement. Objective:Comparison of outcomes and costs associated with knee and hip replacement at designated hospitals and other hospitals. Research Design:Retrospective claims analysis of approximately 54 million enrollees. Study Population:Individuals with insurance from one of the sponsors of this centers of excellence program who underwent a primary knee or hip replacement in 2007–2009. Outcomes:Primary outcomes were any complication within 30 days of discharge and costs within 90 days after the procedure. Results:A total of 80,931 patients had a knee replacement and 39,532 patients had a hip replacement of which 52.2% and 56.5%, respectively, were performed at a designated hospital. Designated hospitals had a larger number of beds and were more likely to be an academic center. Patients with a knee replacement at designated hospitals did not have a statistically significantly lower overall complication rate with an odds ratio of 0.90 (P=0.08). Patients with hip replacement treated at designated hospitals had a statistically significant lower risk of complications with an odds ratio of 0.80 (P=0.002). There was no significant difference in 90-day costs for either procedure. Conclusions:Hospitals designated as joint replacement centers of excellence had lower rates of complications for hip replacement, but there was no statistically significant difference for knee replacement. It is important to validate the criteria used to designate centers of excellence.


Abstract
This study aims to determine what grammatical aspects are used in the Sentilan Sentilun discourse "DPR Library for Whom?" and what grammatical aspects are most dominantly used in the discourse. The method used in this research is descriptive qualitative. This research needs to be done to find out the grammatical aspects of Sentilan Sentilun discourse. In addition, this research is also expected to add the enrichment of research on talk show discourse. This study uses discourse analysis techniques. The data source in this study is the Sentilan Sentilun talk show "DPR Library for Whom?". The data in this study are lingual units in the form of words, clauses, or sentences contained in the speech of the Sentilan Sentilun talk show " DPR Library for Whom?". The data in the study were analyzed using discourse analysis techniques, namely descriptive text analysis, interpretation, and explanation. The results of this study found several grammatical aspects contained in the Sentilan Sentilun text, including references, substitutions, ellipsis, and conjunctions. There are 3 forms of reference grammatical aspects: personal reference, demonstrative reference, and comparative reference. Persona references are 195, demonstrative references are 274, and comparative references are 2. The following grammatical aspect is substitution. The substitution in the Sentilan Sentilun talk show discourse is only in 2 clauses. In addition, the discourse of the Sentilan Sentilun talk show, grammatical aspects of the ellipsis were also found. The ellipsis contained in the discourse consists of 20 words, 31 phrases, 2 clauses, and 1 sentence. While the grammatical aspects of conjunctions are found in several forms, causality is 20 contradictions, 31 excesses 5, objectives 1, additives 20, as many as 13 alternatives, and sequential as many as 7. The dominant grammatical aspect that appears is the demonstrative reference, with a total 274.
Keyword: discourse analysis, talkshow discourse, grammatical aspects.


1. Increase in the energy expenditure of the dog's heart by the addition of adrenaline to the circulating blood increases the utilization of both sugar and lactate.

2. The same holds true for increase in energy expenditure by raising the mechanical work done.

3. Cardiac muscle appears to differ fundamentally from skeletal muscle in the ease with which it uses lactate.

4. It is suggested that the lactate is burned by the tissue to yield energy, whereas the sugar is used to replace glycogen usage. When the blood sugar and lactate have fallen to a low level the heart glycogen is drawn upon, especially if the energy expenditure has been high.

Part of the costs of this research have been defrayed by a grant from the Royal Veterinary College to one of us (J. Y. B.).


Photoacoustic imaging is a non-invasive and non-ionizing imaging technique that combines the spectral selectivity of laser excitation with the high resolution of ultrasound imaging. It is possible to identity the vascular structure of the cancerous tissue using this imaging modality. However, elevation and lateral resolution of photoacoustic imaging is usually poor for imaging target. In this study, three dimension filter delay multiply and sum beamforming technique (FDMAS(3D)) is used to improve the resolution and enhance the signal to noise ratio (SNR) of the 3D photoacoustic image that is created by using linear array transducer. This beamforming technique showed improvement in the elevation by 36% when its compared with three dimension delay and sum beamforming technique (DAS(3D)). In addition, it enhanced the SNR by 13 dB compared with DAS (3D).


TFAA has been used widely for the derivatization of hydroxyl groups in XPS of organic polymers. Unfortunately, in the presence of other nucleophilic groups at the surface like amino groups, these also react with TFAA and a quantification of the different functional group concentrations is impossible. It has been found that the TFAA derivatives of hydroxyl groups and amines, namely the trifluoroacetate and the trifluoroamide, respectively, can be distinguished by the BE of the CF 3 component in the C1s spectrum. While in a trifluoroacetamide the BE is about 292.3 eV, in a trifluoroacetate it can be as high as 294.2 eV in the case of densely packed hydroxyl groups.


The article focuses on the study of semiotic aspects of the cinematic discourse. The sign nature of the cinematic discourse is considered, the interaction of verbal, nonverbal and cinematic semiotic systems aimed at constructing the meaning is determined. The semiotic model of the cinematic discourse is proposed, verbal, nonverbal and cinematic signs of the cinematic discourse which have the features of icons, indices and symbols are distinguished. The semiotic model of the film discourse includes a collective author and collective recipient, a semiotic system, a polycoded utterance, a channel, a mediator – actors, as well as a communicative noise and an inferencial reasoning. The process of the inferencial reasoning is at the heart of the meaning reconstruction by the collective recipient, actualized in the cinematic discourse. Successful meaning reconstruction of the polycoded utterance depends on a common picture of the world and the system of values that exist in the collective consciousness of the author and the recipient. The article highlights the complex relation between the film discourse and the cinematic discourse, whereas the cinematic discourse is considered to comprise the film discourse. The latest includes the process of translating polycoded utterances produced by the collective author. Social and cultural community, a certain historical background predetermine the success of cinematic communication.


The paper introduced the X_raygraphic method cna be used as a fast and effective method to examine and analyse the seed quality by the examination of the seed structure,damage and the infected extent of the seed by pathogenic bacteria.The method can be widely used in the fields of plant seed quality examination,plant breeding,long_term conservation of genetic germplasm grain storage and the quality analysis of food raw material.


The X-ray Universe 2011, Presentations of the Conference held in Berlin, Germany, 27-30 June 2011. Available online at: http://xmm.esac.esa.int/external/xmm_science/workshops/2011symposium/, article id.275


There is provided a method for forming a metal film on a target substrate having a complex-shaped portion and a flat portion, the target substrate being loaded into a chamber which is maintained under a depressurized atmosphere, by sequentially supplying a metal chloride gas as a raw material gas and a reduction gas for reducing a metal chloride into the chamber while purging the chamber in the course of sequentially supplying the metal chloride gas and the reduction gas, the method including: forming a first metal film by supplying the metal chloride gas at a relatively low flow rate; and forming a second metal film by supply the metal chloride gas at a relatively high flow rate.


submitted 13 March 1998 to: "European Conference on Spacecraft Structures Materials and Mechanical Testing", 4 November 1998, Stadthalle Braunschweig, Braunschweig, Germany. This paper is relevant to the following subject category listed in the call for papers: in-jlight experiments and fright data, In-flight measurements of spacecraft environments and behavior


Self-assembly of three flexible bis(pyridyl) molecules with different inorganic acids (HPF6, HClO4, and HNO3) leads to the formation of eight salts, which exhibit diverse architectures involving hydrogen bonding and anion–π interactions. The three types of inorganic anions in these salts formed anion–π interactions with HM+ and H2M2+ except for 2, in which the six F atoms were involved in hydrogen bonds. Anion–π interactions produced diverse motifs of one (anion)-to-one (cation) in 1, 3, 4, and 6, two (anion)-to-one (cation) in 5 and 7, and (4,4) layer in 8. Hydrogen bonds resulted in interesting supramolecular architectures, such as right- and left-handed helical chains in 3, 2-fold interpenetrating networks in 5, and 3-fold interpenetrating networks in 8. Structural analyses indicated that the conformations of the three flexible asymmetrical bis(pyridyl) molecules and the non-covalent bonding interactions, such as hydrogen bonds and anion···π interactions, play crucial roles in the final architectures of these salts. Thermogravimetric analyses indicated that the thermal stability of the eight salts decreased in the order of perchlorates, hexafluorophosphates, and nitrates. The emission intensity of the perchlorates is much stronger than that of the hexafluorophosphates, nitrates, and their corresponding organic molecules in the solid state at room temperature.


AbstractThis paper investigates the predictability of heavy precipitation in the economically important Waikato River basin of New Zealand. A 2-yr archive of Global Forecast System (GFS) model data to +180 h for the period August 2005–August 2007 forms the basis of the study. GFS model predictions of precipitation are compared to surface measurements from 22 stations in and around the river basin. Categorical hit rate and bias, threat score, false-alarm ratio, probability of detection, RMSE, skill score, and mean error are all plotted as a function of model lead time for the 2-yr period.The general synoptic structures of heavy precipitation events are often identified at long lead times. An example is shown for January 2006 when heavy rainfall is identified by GFS at +150 h, accurate location and timing is given at +48 h. Precipitation amounts are systematically underpredicted by GFS and the spatial distribution of rainfall is limited by model resolution. The value of GFS lies in its ability to provide ea...


The medium is a modification of MacConkey's agar and is based on the observations of Stacy and Webb (1947) that dehydrocholic acid, one of the bile acids, is nontoxic for staphylococei. After some trials, a medium of the following composition (in g per L) was devised2: Sigma pH 7 to 9 tris(hydroxymethyl)aminomethane buffer, 1.3; dehydrocholic acid, 1.5; yeast extract (Difco), 1.0; proteose peptone (Difco), 10; neutral red, 0.075; agar, 12. The pH of this medium with our reagents is 7.6. To this basic medium is added the desired carbohydrate at a concentration of 1 per cent. Since dehydrocholic acid is insoluble at pH 6.8 or less, the reagents should be dissolved in the order listed, except neutral red which is best dissolved in a small volume of water and added to the other ingredients. The completed medium is pale red in color. On plates, colonies of fermenters are dark red, whereas nonfermenters are white. The appearance of mannitol positive and negative mutants of Staphylococcus aureus and Escherichia coli on this medium is shown in figure 1.


Xiahe county in Gannan Tibetan autonomous atate is a place worth to research for the reason the Han and Tibetan culture cross.The paper,based on the culture profile and social or integrated tribe analysis,it's found that,there are following characteristics in town,farm belt and pasturing community culture of Tibetan:for the way fof making living,farm belt more depend on agriculture,pasturing area more depend on pasture,and the occupation in the town are various.for the way of living style,town and farm belt are more impacted by the Han People,pasture remains more original Tibetan custon.for the community institution,administration is incompact in pasture area,and the traditional community institution is more powerful,the village levelinstitution of farm belt and town is relax.for the family structure,pasture have more expanding family,farm and town have more core family.for the value conception,modernization sense is weak in pasture but comparatively strong in fam belt and pasture.


Lepidodendracean fructifications with well-preserved megagametophytes are described from Pennsylvanian petrifactions of eastern Kentucky. One cone is megasporangiate with one functional alate spore in each sporangium; the other cone is bisporangiate with spinose megaspores and papillate microspores. Both strobili have megaspores that contain prothallia with rhizoids and well-developed archegonia. Ontogenetic stages of megagametophytic development in these cones are comparable to stages that occur in extant heterosporous lycopods. This study provides further evidence of a close phylogenetic relationship between the lepidodendrids and the extant genus Isoetes.


Adult septic hip arthritis poses serious problems, especially when the infection is secondary to prosthetic arthroplasty or associated with osteomyelitis of the femoral head and neck. Conventional treatment consists of thorough debridement of all infected tissue, the administration of appropriate culture-directed antibiotics, and a secure primary or delayed closure of viable fascia and skin with suction over suction-irrigation tubes.1 In general, resectional arthroplasty is indicated and almost always effective in controlling infection in cases that do not respond to debridement and antibiotic treatment. However, recalcitrant infection with wound complication following resectional arthroplasty occurs in some cases and is always a difficult problem. Approximately 10 to 20 percent of patients had chronic, unhealed, draining hip wounds after resectional arthroplasty.2 Because of the extreme fibrosis and impaired vascularity of the surrounding soft tissues, the patient is often left with a deep, extensive, unhealed wound extending from the lateral thigh deeply into the acetabulum.3 The open wounds with fibrous walls, which are caused by the local response to infection and repeated operations, do not close or heal easily without wellvascularized soft tissue in the wound. The use of muscle flaps, either local transposition or microvascular free tissue transfers, has been reported in treating these chronic deep wounds.1–4 Nevertheless, few patients have received secondary total hip arthroplasty after a tissue transfer.3,4 This report describes our successful resolution of two intractably infected hips using pedicled vastus lateralis muscle flap transposition and our satisfactory functional outcomes after secondary total hip arthroplasty.


How often should I spend the time and money to soil sample? How many samples should I collect in a field? How is the profit from soil sampling affected by crop and fertilizer prices? Do higher grain prices coupled with higher fertilizer prices mean more, or less, fertilizer should be applied? In terms of cash rent or land value, how much more is land worth that has higher soil fertility? Is grid soil sampling worth it's cost? Or, can electronic sensors do an adequate job for less money? By touching on a broad array of soil sampling issues, this session will begin to answer questions like those noted here.


Many studies have been conducted on sensitivity analysis in DEA which focus on changing the value of data or reallocation of inputs. In this article, some models have been presented which can be used for allocating one or more new inputs between the DMUs in a way that some of the inefficient units have been modified to efficient units. These models have been offered for both crisp inputs and fuzzy inputs. The presented model allocates the new inputs between the DMUs in a way that the distance of new inputs from the fair allocation is minimized by applying the Chebyshev's norm. The mentioned models are utilized in four numerical examples and the related results are reported. To the present, the related studies have been focused on changing the value of the old inputs, however, this article paid particular attention to allocating the new input(s) between the DMUs.


s: Background: Municipal or household wastes are often generated from several sources where variable human activities are encountered. This study is to conduct waste characterization survey at solid waste dumpsites around markets, Semiindustrial and residential areas Materials and Method: On the spot site waste segregation with the use of human scavengers was conducted at each of the fifteen (15) waste dumpsite. The major equipment used are: 25liters plastic bucket, medium size weighing scale of 0 to 150kg range and hand shovel, Data were obtained in percentages of the total solid waste at each of the dumpsites. The mean percentages as per each classified dumpsite were graphically analyzed. Results: At Market dumpsites, dominant waste constituents were: Plastic bottles and food/organic > Polyethylene nylon > paper > glass bottles. Whereas in the semiindustrial areas: Plastic bottles >Polyethylene nylon > food waste > Paper. In the residential area, the major constituents were: Food/organics 30% > Polyethylene nylon 25% > Plastic bottles 22% > paper 15% > Glass 5%. Conclusion: Waste characterization survey shows that Food/organic, paper, plastics, polythene are the major constituencies at all solid waste dumpsites. Batteries and bulbs also occur but small in quantity.


A groundwater inrush occurred again when excavation came to the pregrouting interval in the auxiliary inclined shaft,which submersed the shaft of the Heilong Coal Mine in Shanxi.The main cause was that the poorness of the fracture stability was formed during the interaction of soft clay and grout in the first grouting process.The method "distributary to relieve pressure then to prevent water inflow" was taken,thus the uncontrollable gushing was changed into controllable gushing and grouting.The borehole was used to examine the effect of the grouting,and the results show that the effect was good.This paper provides references for similar grouting in rock mass which is filled with soft clay.


Acquired somatic mutations in ATRX , an X-linked gene encoding a chromatin-associated protein, were recently identified in four patients with the rare subtype of myelodysplastic syndrome (MDS) associated with (cid:1) thalassemia (ATMDS). Here we describe a series of novel point mutations in ATRX detected in archival DNA samples from marrow and/or blood of patients with ATMDS by use of denaturing high performance liquid chromatography (DHPLC), a technique sensitive to low-level mosaicism. Two of the new mutations result in changes in amino acids altered in previously described pedigrees with germline ATRX mutations (ATR-X syndrome), but the hematological abnormalities were much more severe in the ATMDS patients than in the corresponding constitutional cases. In one ATMDS case where DNA samples from several time points were available, the proportion of ATRX -mutant subclones correlated with changes in the amount of hemoglobin H. This study strengthens the link between acquired, somatic ATRX mutations and ATMDS, illustrates how molecular defects associated with MDS and other hematological malignancies masked by somatic mosaicism may be detected by DHPLC, and shows that additional factors increase the severity of the hematological phenotype of ATRX mutations in ATMDS. mutations in the ATRX gene (20+1G>A in the exon 1-intron 1 canonical splice donor site, and 236C>G; S79X) present in myeloid but not lymphoid cells in two patients with ATMDS; ATRX mRNA splicing abnormalities were observed in two other ATMDS the causative genomic 16 . The two ATMDS-associated ATRX mutations and two ATRX splicing abnormalities described to date have never been reported in ATR-X syndrome. One possible reason might be that the ATRX mutations associated with the much more severe hematopoietic impairment typical of ATMDS – where the number of HbH-containing erythrocytes usually ranges from 10% to 90% and the (cid:1) / (cid:2) globin chain synthesis ratio is often <0.1 – are lethal during development when inherited. However, here we report eight new ATMDS-associated acquired ATRX mutations and an additional ATRX base pair change of uncertain significance detected by denaturing high performance liquid chromatography (DHPLC). This series includes one mutation identical to a previously described germline ATRX mutation and another mutation that alters the same amino acid as a constitutional ATRX mutation. In addition, several of the newly characterized mutations result in the loss of highly conserved domains of the ATRX protein that are also lost in constitutional pedigrees. In each case, the ATMDS hematologic findings are more severely abnormal than in the previously described cases where the ATRX mutation was inherited rather than acquired. These findings expand the spectrum of acquired ATRX mutations and demonstrate that these are the primary mutations leading to (cid:1) thalassemia in ATMDS. However, these observations also show that additional factors in the abnormal erythroid precursors of patients with ATMDS must contribute to the severe defect in (cid:1) globin synthesis. can powerful tool detecting mutations in of in importance of in important implications for identifying other genes that may be mutated in MDS.


The paper examines time-series patterns of job and worker flows in a newly industrializing economy (NIE). Using plant-level data from the Taiwan manufacturing sector, the cyclical behaviour of job reallocation and its relation with worker turnover is analysed. It is found that job reallocation and labour turnover are procyclical, at both the aggregate and (two-digit) industry levels. The share of worker turnover caused by gross job reallocation is 17%, suggesting the majority of observed worker turnover reflects rotations of positions that are neither created or destroyed. There is substantial heterogeneity in plant-specific job and worker turnover patterns. Job creation and job destruction rates are higher among small plants and private-sector plants. The private plants are more dynamic than public plants in terms of worker turnover. Controlling for year and industry effects, it is found that job creation and worker turnover are both higher in export-oriented industries.


Institute of Information Technologies of the National Academy of Sciences of Azerbaijan, AZ1141, Baku, st. B.Vahabzade, 9A. Abstract. The article emphasizes the importance of a well-thought-out demographic policy for any state and lists the main tasks of demographic policy. The important role of demographic research is also noted. On their basis recommendations are developed for a more rational distribution of the population and improvement of its composition. The need for demographic research, as well as the penetration of information technologies into all spheres of human life and activities, led to the emergence of a new direction of demography – electronic demography (e-demography). In this regard, the article proposes an approach to the development of an electronic demographic decision support system using data warehouse (DW) technologies and interactive analytical processing OLAP. Thanks to these technologies, you can see the overall picture of demographic processes. This allows for high-level demographic research and supports demographic decision-makers. Because of the many types of demographics and the large number of indicators, the DW architecture is proposed as a data mart (DM) bus architecture with associated DM. This architecture consists of two levels: the first level is information from various e-government registers, the second level is DM. To implement the approach proposed in the article, an experimental e-demographic DSS was developed. It includes DW and OLAP. The DW architecture is a bus of interconnected DM. OLAP cubes are built on these DM. Their dimensions are indicators of the respective types of demographics. The system is implemented for personal computers running Windows 7, Windows 8, etc. The OLAP implementation environment includes an Excel Pivot Table, which is an OLAP visualization. The number of persons in different dimensions is determined by the COUNT aggregate function. The practical application of this approach is illustrated by the example of two DM. The first DM relates to descriptive demography and the second DM relates to geographic demography. OLAP cubes are built from these DM. OLAP operations let you view cubes in different slices. In conclusion, the importance of the electronic demographic system is shown, as well as the need for the development of this area in the future.


[Objective] The aim of research was to screen the optimal medium of anther culture of srawberry Lasong No.7.[Method] The relationship between bud size and anther development was builded.With the anthers of single nuclear aside period as explants,with MS as basic medium,added different hormones and cytokinin to establish regeneration system,the effects of different hormone combinations on anther culture of strawberry were studied.[Result] Optimal sterilizing method was treating with 70% alcohol 30 s;the optimal pretreatment method was low temperature at 4 ℃ for 24 hour.The best medium for callus induction was MS supplemented with 0.2 mg/L NAA and 2.0 mg/L 6-BA;the best medium for shoot differentiation was MS supplemented with 2.0 mg/L 6-BA and 0.1 mg/L KT,the value-added multiplier was 3-4;the best rooting medium was 1/2 MS,the rate of rooting was 100%.[Conclusion] The excellent regeneration system of strawberry anther was obtained.