The paper uses the phase locked loop technique based on statistical prediction,introduces the design scheme and implementation principle of the technology,through the full degree of FIFO to control the charge pump output corresponding level signal,the signal is made use of controlling the output of the VCXO clock,to restore the receiver clock frequency and data in sync,and the jitter is small.


A new design of long wavelength band erbium-doped fiber amplifier (L-band EDFA) is experimentally demonstrated based on ring laser cavity to obtain better gain flatness as well as gain clamping characteristics. It uses a fibre Bragg grating (FBG) to provide laser feedback, which is arranged to propagate in the opposition to the signal in the amplifier by a pair of circulators. A flat-gain spectrum with less than 1.1 dB variation between 1568 nm and 1604 nm was observed with the laser wavelength at 1560 nm. A gain-clamping effect also was observed with this configuration, which provided a constant gain for all tested input signal powers from -40 dBm until 0 dBm.


Here within we describe our practical experience with the orchestration of human computer interaction (HCI) methods and extreme programming (XP) software development processes. We show how we selected the applied methods based on the motivating goals and values of developers by using a means-end approach. We discuss our experiences with the applied methods and conclude with some advice on which HCI methods are optimally supporting extreme programming developers. Author


The research advance of detection method of fluorion in soil was reviewed. The characteristics of soil sample pretreatment method and detection method were discussed in detail,which will provide basis for selecting corresponding detection method for fluorion in soil.


"In any human society, where people must, of necessity, interact there are bound to be intrigues. But this should not deter one from pushing ahead with what one believes in". Unimna Angrey


The main factors that need to be concerned in the research on the relationship between sewage interception ratio and river quality are the condition of rainfall and runoff,the ratio of separate system,the pollutant discharging to river and the water quality target.Non-point source pollutants that flow into river with runoff are the most important factor to be studied.At present,Shenzhen sewerage system is mainly a combined system,which includes rainwater and sewage water.Non-point source pollution accounts less for annual total pollutant output,but non-point source pollution can't be ignored because of its outburst in short time.


The invention is applied in the field of data transmission, and provides a high-speed and low-speed compatible interface component, a bus terminal and a bus communication system. The interface component comprises a protocol unit, a low-speed signal transceiver unit and a high-speed signal transceiver unit. In the embodiment of the invention, the protocol unit can finish GJB289A protocol conversion and modulation and control the low-speed signal transceiver unit and/or the high-speed signal transceiver unit to receive and transmit signals by corresponding GJB289A buses to realize the high-speed and low-speed compatible interface component. The high-speed and low-speed compatible interface component can realize high-speed and low-speed data transmission by utilizing a conventional GJB289A bus communication system without changing a conventional transmission network, along with low development cost, short period and low risk.


The utility model discloses a power pump station for a diesel engine. An oil tank is provided with two oil-way pipelines. One oil-way pipeline is connected to a tilting axis type axial plunger pump through an oil suction filter and an oil inlet ball valve. The diesel engine is arranged beside the tilting axis type axial plunger pump through a connecting support. The other oil-way pipeline is divided into a branch three and a branch four after passing through an air cooler and a one-way valve. The branch three is connected to an oil outlet way pipeline of the tilting axis type axial plunger pump after passing through an electromagnetic relief valve. The oil outlet way pipeline of the tilting axis type axial plunger pump is connected to an electro-hydraulic proportional directional valve through the one-way valve. The electro-hydraulic proportional directional valve is connected to a hydraulic motor through a balance valve. The branch four is connected to the hydraulic motor after passing through the electro-hydraulic proportional directional valve and the balance valve. A water tank is installed beside the oil tank and provided with a water temperature alarm. The power pump station for the diesel engine is capable of achieving the technical parameters required by enterprises, stable and small in size.


Part One: The main work in this paper is on properties of the logarithmic integral $Li(x)$ and the prime counting function $\pi(x)$. Let define the truncation of the logarithmic integral $Li(x)$ as \[ \pi^{*}(x,N):=\frac{x}{\log x}\sum_{n=0}^{N}\frac{n!}{\log^{n}x} \] and write \[ |Li(x)-\pi(x)|\leq|Li(x)-\pi^{*}(x,M)|+|\pi^{*}(x,M)-\pi^{*}(x,N)|+|\pi(x)-\pi^{*}(x,N)|. \] Firstly, we prove $Li(x)-\pi^{*}(x,M) 0$, and $x\geq x_{\beta}$ which satisfies $(\log x_{\beta})^{2}/x_{\beta}^{0.0327283}\leq\beta$. Then there are \[ \frac{\pi(x+\Phi(x))-\pi(x)}{\Phi(x)/\log x}=1+O(\frac{1}{\log x}) \] and \[ \lim_{x \to \infty}\frac{\pi(x+\Phi(x))-\pi(x)}{\Phi(x)/\log x}=1. \]


This study developed a research from Steenkamp et all (1999) about the antecedents of consumer innovativeness.. In this study, consequence variables were added which was the effects of consumer innovativeness, namely new product (Service) innovation behavior, that was the extent to which a person adopts an innovation relatively earlier than the environmental community. The objects used in this study were consumers in ten types of creative industry businesses in Surabaya. To test the research hypotheses used the Structural Equation Model with the WARP PLS program. The results of this study proved that personal values had an effect on consumer innovativeness. Consumer context specific disposition had no significant effect on consumer innovativeness. The results also concluded that consumer social demographic had no significant effect on consumer innovativeness. This research also concluded that consumer innovativeness had a significant effect on consumer innovation behavior (new product /service innovation behavior).


Osteopoikilosis (OPK) is an asymptomatic, rare bone dysplasia. It causes an increase in bone density. The etiology and pathogenesis is unknown. OPK is generally diagnosed incidentally on plain radiographies which were performed for other locomotor system symptoms. Diagnostic lesions of OPK are typically diffuse, round, symmetrically shaped sclerotic bone areas. Laboratory findings and bone scintigraphy are usually normal. OPK should be considered in the differential diagnosis of osteoblastic bone disorders. OPK is a benign disease and invasive diagnostic procedures as well as aggressive treatment modalities should be avoided. In young individuals who have elevated scores on dual-energy X-Ray absoptiometry measurement, OPK as well as other sclerosing bone disorders would be considered. (From the World of Osteoporosis 2010;16:25-8)


Brian Street joined King's College London as Professor of Language Education in 1996.  For the best part of twenty years Brian was an enthusiastic and tireless colleague and teacher in the School of Education, Communication and Society.  Already a well-established scholar, he continued to develop and extend his ideas in language and literacy theory and practice throughout his time at King's.  He drew on his intellectual grounding in cultural anthropology and literary studies in highly productive and imaginative ways when working with theoretical and educational matters (see Castenheira and Bloome, 2021 for an informed account of his intellectual trajectories).  His own professional conduct was infused with a strong commitment to social justice and widening participation in public education.  As colleagues and students we have had the privilege and benefits of working with Brian.  In this symposium article, we put together three accounts that provide glimpses of Brian's ways of living and working as an intellectual activist.


A model of visual information processing based on the central neuronal mechanisms of vision is proposed.The model based on physiological mechanisms of human vision can effectively simulate visual information processing in humans.Experiments were designed to simulate the course of information processing by the retina.The corresponding retinal image was generated.The receptive field of simple cells received the retinal image as the input image.The system received peripheral information and formed a contour edge image through stimulation in a specific direction.The experimental results show that the model generates a good simulation.


Prediction and control of thermal residual stress are particularly important for the design and manufacture of multiply stiffened welded structures. The present study shows a FEM (finite element method) study aimed at illustrating a complex and dangerous effect, the distortion. An aggressive thermal process or the welding process in particular generates permanent plastic strains. Some specific geometries were chosen and different studies were performed. Thus, different sequences were analysed trying to minimize inherent strains and residual stresses over the structure.


The well-known "zone method", treats thermal radiation in an enclosure in a global manner so that reliable estimates of this mode of heat transfer can be obtained in systems such as gas-fired furnaces. Consequently the paper employs a two-dimensional thermal radiation model in which both the height and length of the furnace was divided into surface and volume zones. An isothermal computational fluid dynamics simulation was used to estimate the relative mass flow rates, and hence enthalpy flows, into or out of each volume zone. This simplified approach was considered to provide a reasonable estimate of the appropriate inter-zone mass flows since the use of small-scale experimental, near ambient temperature models has been shown in the past to give useful data on flow related behaviour of combustion systems. The computing times resulting from the coupling of a multi-zone model with a single isothermal computation of the flows are relatively short so that the transient performance of the reheating furnace can be analysed. The mathematical model was thus used to predict the fuel consumptions and load temperatures in a gas-fired furnace heating steel bars to a nominal discharge temperature of 1250°C over a typical transient operating period of 8 hours including the start-up from cold. The influences of burner geometry as well as the effects of changes to the value of the roof set point temperature which was used to control the thermal input to the burners were studied. The effects of varying the position of the roof temperature control sensor relative to the burners and of changes in the roof construction were also investigated.


Summary The following observations were made on plasma hexosamine levels in the rat: 1) there is an increase during the period of rapid growth, 2) no significant diurnal changes could be demonstrated, 3) the amount of food eaten is important in the maintenance of a normal level, 4) stress increases and fasting lowers the plasma hexosamine level in the normal rat, 5) fasting prevents the expected increase following stress.


Watchings of Canopus as a herald of the winter were important duties of ancient priests-astronomers on Easter Island. All the analysed data witness that this star was observed during the first and second voyages from Mangareva to the island. The names of king Hotu-Matua (Anua-Motua) and his father Tara tahi have been decoded. Several rongorongo records from the Esteban Atan manuscript have been deciphered advantageously. The new view at a painted barkcloth figurine connected with the bird-man cult has been offered. Some data about watchings of Aldebaran, the Pleiades, the sun, the moon, Venus and Mars have been collected as well.


Correspondence Ralf Weiskirchen, Institute of Molecular Pathobiochemistry, Experimental GeneTherapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D52074 Aachen, Germany. Email: firstname.lastname@example.com Funding information Deutsche Forschungsgemeinschaft (SFB/TRR57), Grant/Award Numbers: P13, Q3; Interdisciplinary Centre for Clinical Research within the Faculty of Medicine at the RWTH Aachen University, Grant/Award Number: O3-1 K E YWORD S : N/A


Aerococcus urinae is a rarely reported pathogen usually causing
mild urinary tract infections, but serious complications such
as endocarditis and septicemia have also been described. It
might be easily missed or misidentified using commercial
detection systems. To our knowledge, fourteen patients of A.
urinae infective endocarditis, including 8 fatal cases, have
been reported in the literature so far. Here we describe a new
case of blood culture negative infective endocarditis in
69-year-old male. The patient recovered fully after treatment
by aortic valve replacement and antibiotics. The causative
agent was identified from the valve by broad-range PCR.


From second law evaluations (entropy or exergy evaluations) it is generally known that thermodynamic losses of boilers and furnaces are much higher than the thermal efficiencies do suggest. With thermal losses of around 5 % the thermodynamic losses (exergy losses) of a boiler can be 50 % or more. The combustion process is responsible for a significant part of these losses. Various atmospheric combustion processes are investigated in order to obtain a better insight in the effect of the main design parameters like the applied fuel, its composition and moisture content, the air factor and the air preheat temperature. Therefore a series of system calculations with natural gas, hard coal and wood as fuel have been made. Value diagrams have been derived to visualise the exergy loss of combustion and to explain their cause. For the investigations the computer program Cycle-Tempo has been used to perform the necessary system calculations, to draw value diagrams and to analyse the results. It appears that the type of fuel and the extent of air preheat mainly determine the exergy loss of combustion. Preheating of combustion air can reduce the exergy losses of combustion considerably. But even with air preheat temperatures up to 1000 ̊C exergy losses of combustion are still high.


Brasilia is perhaps the most emblematical of contemporary planned cities. We will approach its formation process from the point of view of one of its units, Vila Planalto, wich provides a unique perspective insofar as it is an unpredicted urban nucleus inside Brasilia Pilot Plan. Vila Planalto was a worker's camp prior to Brasilia's inauguration, and afterwards a clandestine settlement for more than 30 years until its final recognition as national heritage, witness to the birth of the new Brazilian capital. The concept of "social supports" (Robert Castel, 1995) will come into play as crucial means to Vila Planalto's survival. How did a dejected space manage to become a site for shared memory ? We will follow Vila Planalto's trajectory from its foundation and trough its formation, consolidation, dynamics and prospects.


Humic materials play an important role in nature and therefore they are intensively studied. Recently, it was confirmed that humic substances represent a complex mixture of many compounds of rather low molecular weight [1-6]. Humic materials have been found to be complex, negatively charged polymers, containing many various functionalities associated into the aliphatic aromatic backbone structure [7]. This can explain the presence of both hydrophilic and hydrophobic sites in their structure.


Crude oil pollution of the soils in Niger Delta region of Nigeria is common due to oil exploration, exploitation and transportation. Crude oil spillage on soils is an environmental problem which has to be prevented or controlled in order to achieve the basic need of soils for plants and animals usage and benefits. The objective of this study was to examine the effect of oxygen diffusion on the physicochemical properties of petroleum contaminated sandy soils at 100cm depth with the availability of indigenous microorganism in the impacted soils. The soil samples were subjected to soil analysis after pollution with Bonny light crude oil. The purpose of the pollution of the soil samples was to simulate conditions of major crude oil spill. Oxygen was diffused through the impacted soils in reactor C. Analysis of physicochemical properties of the sandy soils includes pH, Electrical conductivity, Total organic carbon, Total Nitrogen, Moisture content, Phosphorous and Total petroleum hydrocarbon at two weeks interval for six weeks using standard methods. The analysis indicated that bioremediation was faster in the soils at the depth of 100cm with oxygen diffusion. The study showed 71% reduction in TPH concentration, pH increase from 5.48 to 7.28, Electrical conductivity increased from 98.6 to182.0μş, Moisture content decreased from 12 to 10%, Total organic carbon reduced from 2.210 to 1.693%, Total Nitrogen decreased from 0.191 to 0.082% and Phosphorous reduced from 0.84 to 0.15mg/kg at the end of the study. Physicochemical properties of the treated Sandy soils showed similar soil characteristics as compared with the initial conditions of the soil before contamination with Bonny light crude oil, which indicated a positive results of the role of oxygen diffusion on bioremediation of petroleum contaminated Sandy soil at 100cm depth.


The papers in this volume cover a wide range of topics, from user requirements for 'smart' sensors to the development of innovative solid-state devices. By definition, a 'smart' sensor can, by means of its data/information processing capability, extract much more information than a simple sensor from the received physical signals, disregard or discard data with little or no information content, and handle efficiently the large volumes of data to be generated in future spacecraft. User concepts for 'smart' sensors are considered, and the topic of data processing systems is addressed. Attention is given to advanced device technology which brings forth unique device concepts applicable to 'smart' sensors. Also discussed are data preprocessing techniques.


Objective To observe the variation of metal ion(Al,Fe,Cu,Mn,Zn) levels of peripheral tissues(cardiac,liver,spleen,lung,kidney,plasma) in chronic aluminum overload rat.Methods SD rats were orally administered aluminum gluconate(Al3+ 200 mg/kg),once a day,5 days a week,for 20 weeks.The metal ion levels were detected by methods of ICP-AES.Results The chronic aluminum overload significantly resulted in an increase of Al level in rat cardiac,liver,spleen,lung and kidney.The levels of Mn in rat liver and spleen were increased and the levels of Mn in rat lung,kidney and plasma decreased in aluminum overload rat.Fe level of cardiac,liver,spleen and kidney were increased in aluminum treated rat,while the levels of Fe in rat lung and plasma were decreased.An increased of Zn level in rat cardiac,spleen and kidney,a decreased of Zn level were observed in rat liver,lung and plasma.Administration of aluminum also induced an increasing of Cu level in rat liver and spleen while decreasing of Cu level in lung,kidney and plasma.Conclusions Chronic aluminum overload can lead to the imbalance of homeostasis of metal ion in rat peripheral tissues.


Differential Evolution (DE) is a population based search algorithm that comes under the category of evolutionary optimization techniques. It is an improved version of GA, and is exceptionally simple, significantly faster & robust at numerical optimization and is more likely to find a function's true global optimum. In the present study, DE is used to solve the classical optimization problem of water pumping system. Comparison is made with Branch & Reduce algorithm. The results indicate that performance of DE is better than the Branch & Reduce algorithm.


G laucoma drainage devices are being increasingly used in the treatment of advanced glaucoma refractory to medical therapy or in cases that have failed trabeculectomy with antimetabolite. The Ahmed Versus Baerveldt (AVB) Study is an international, multicenter, randomized clinical trial comparing the two most frequently used devices. Five-year results have been recently published providing high quality evidence to guide a surgeon's decision on which device to use.


Abstract. The purpose of this application, under Article 75.6 of the Code, is to conserve the specific names of Anolis chlorocyanus Duméril & Bibron, 1837 and Anolis coelestinus Cope, 1862 in their accustomed usages. The syntypes of the former species are conspecific with the only available syntype of the latter; however, for about 85 years the name A. coelestinus has been applied to the species represented by these types. For the same period of time the name A. chlorocyanus has been consistently applied to another equally well-known taxonomic species. It is proposed that the Commission use its plenary power to set aside the type status of the syntypes of A. chlorocyanus in order to stabilize the current and long-established usage of the names A. chlorocyanus and A. coelestinus. It is further proposed that the specimen SMF 97845 be designated as the neotype of A. chlorocyanus Duméril & Bibron 1837. SMF 97845 is an adult male from El Limón, Province Samaná, Dominican Republic, that represents the taxonomic species traditionally referred to as A. chlorocyanus.


The distribution substation is an important part of distribution power system automation system.Aim at the problem that general industry computer and Windows 2000 operation system is low in efficiency and is bad in stability.Design a distribution substation.The distribution substation based on PC104 mainboard and the embedded operation system Windows CE.After run on the enterprises of power supply practically,improve alternative sampling algorithm is stability,reliability,can raise maintenance and extension of distribution substation.


The article describes the main idea of the concept of future teacher's ethical awareness development which is devised in the context of methodology layers. The author reveals the content of methodology layers; substantiates the approaches realized on this or that methodology layer and adequate to these approaches principles of developing future teacher's ethical awareness.


A pathway to improve the light-harvesting efficiency of dye-sensitized solar cells based on porous electrodeposited ZnO films is presented. Cosensitization with the indoline dyes D149 and D131 and the squaraine dye SQ2 leads to panchromatic light harvesting and photovoltaic activity. When coadsorbates are employed to prevent dye aggregation on the ZnO surface, an increase in the short-circuit photocurrent and overall efficiency compared to reference cells with D149, or D149 and D131 is attained. The overall performance of cosensitized cells containing SQ2, however, is limited by low open-circuit voltages and fill factors. By use of electrochemical impedance spectroscopy, current–voltage characterization in the dark and under illumination, and charge extraction measurements, recombination reactions and the distribution of trap states in the ZnO films are investigated, and the origins of the limited open-circuit voltages and fill factors in cells with SQ2 are revealed.


About 400 Aramaic ostraca from a place at or near Maqqedah between Hebron and Lachish, have been published in 1996. With previously published ostraca from Arad, Beersheba and Khibet el-Qom, they give us information on the economy and administration of the IVth c. BCE Persian province of Idumaea. A preliminary look at these new documents, at least partly connected with taxes and tax-collectors, are evidence of an agricultural economy. Wheat and barley, with their various kinds of flour, are often mentioned, as well as olive-oil and straw ; wine is rarer, perhaps because of North-Arabic influence. Donkeys and camels were used as track-animals. Units of silver are mentioned and the use of coins is possible but not certain. One ostracon seems to allude to the trade of slaves.


WHILE the subject on which I have been asked to speak to you is "Tumours of the colon -and. rectum," the greater interest is carcinoma and the paper will be limited very largely to that subject. -In Massachusetts there are about 5,000 deaths from carcinoma per year; 12 per cent of this number are in the rectum and colon, and of these 600 cases, 65 -per cent occur in the rectum. After making a very liberal estimate of the number of radical operations, it is difficult to believe that 15 per cent of the total number are given a radical operation. If but 15 per cent of the total-number of patients in the state are operated upon, and. some of us operate upon between 50 and 60 per cent of the cases seen, it must be evident that the.diagnosis is made very late and that many patients never see a competent authority as to the advisability of operation. As further evidence that there is a lack of interest among physicians,. it is a fact that one osteop4thic physician has sent me more cases of carcinoma of the rectumn than all the regular physicians in the.same region. It is a fact also that certain physicians, even in small towns, become interested in the condition and find cases of carcinoma of the colon and rectum frequently, while others never find one. In other words, physicians find these cases when they are interested. I have said many times that a diagnosis has not been made in less than the a-rerage of eight months because of the lack of interest and not because of the difficulty im


This is a depth psychological study of a stirring, uncanny, and nearly inexpressible moment called the Evocative Moment. As an interdisciplinary study, it integrates poetic, mythological, and philosophical material in an effort to give voice and form to a relatively formless experience. At heart, it is an offering to and a calling for the further development of a depth psychological poetics that draws nearer to inchoate experience than is permitted by conventional language and forms of inquiry. The study approaches the Evocative Moment by placing it within the context of key interdisciplinary ideas. As a search for a way of understanding itself, the study then develops a broadly based hermeneutic phenomenology, rooted in a qualitative, human scientific research approach. Within a central clearing (temenos), it places poetic-phenomenological explorations in dialog with selected resonant texts. The intention is not to represent but to present, to evoke, even to become the Evocative Moment itself. Although its phenomenology and birth into language are, essentially, its research results, certain patterns and meanings are gleaned in intuitive reflection. As a content, the Evocative Moment suggests Dionysian remembrance and dismembrance, primordial temporality, the paradoxical presence of absence, and the uncanny homecoming to being. As a process, it manifests either spontaneously or in an emotional evolution through tension and anxiety, faith and letting go, becoming and speaking, mourning, and again, faith in letting go. Clinically, the study espouses an intuitive and radically receptive therapy that cultivates and e-vokes (lifts into speech) implicit moments like the Evocative Moment. Exercises are recommended to facilitate the development of such a therapeutic capacity. The study frames psychotherapy as a practice that must achieve The dissertation citations and abstracts contained here are published with permission of ProQuest Information and Learning Company. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by addressing your request to ProQuest Information and Learning Company, P. O. Box 1346, Ann Arbor, MI 48106-1346 USA. Telephone (734) 761-7400; Email: firstname.lastname@example.com; Web Site: http://wwwlib.umi.com/dissertations. Journal of Poetry Therapy (June 2010), Vol. 23, No. 2, pp. 119 128 ISSN 0889-3675 print # 2010 National Association for Poetry Therapy DOI: 10.1080/08893675.2010.482815 depth as depth of field, both within the consulting room (the intersubjective field) and within the field of the world. As an experiment in depth psychological poetics, the study suggests that depth psychology must resist becoming seduced by theoretical abstractions, privilege forms of inquiry that reflect the native fluidity of psychic reality itself, and acknowledge that there are subtle, evanescent states, like the Evocative Moment, that are accessible only by way of a via poetica, which speaks not by translating but by carrying meaning. Indexing (document details) Advisor: Panajian, Avedis School: Pacifica Graduate Institute School Location: United States California Keyword(s): Depth psychology, Poetry, Hermeneutic phenomenology, Evocative moment Source: DAI-B 70/05, p. 3168, Nov 2009 Source type: Dissertation Subjects: Philosophy, Clinical psychology, Language Publication Number: AAT 3361024


Weakly-supervised image semantic segmentation is a popular technology in computer vision and deep learning today. The main goal of weakly-supervised semantic segmentation is to train a model by images with only coarse or sparse annotations. Specifically, it assigns a label to each pixel through coarse label refinement or sparse label propagation, etc. The existing semantic segmentation has a wide range of applications, which includes pedestrian detection, autonomous driving, medical image segmentation, etc. However, fully-supervised semantic segmentation requires pixel-level annotation, which is expensive in manpower and time, and more and more works have focused on weakly-supervised semantic segmentation in recent years. Thus, this paper provides a review of weakly supervised semantic segmentation. Firstly, this paper summarizes the state-of-the-art research results of weakly-supervised semantic segmentation. Secondly, the widely-used datasets and semantic segmentation models are introduced. Finally, this paper analyzes the existing problems and future development directions in the field of weakly-supervised semantic segmentation.


With enrollment in computer science (CS) programs continuing to rise, effective student advising is increasingly important to improve student performance and retention. Yet many advising strategies focus on identifying struggling students based on GPA after the semester ends. By the end of the semester, it is too late to add or drop courses, and often too late for students to benefit from other resources which could have helped them succeed in the previous semester's courses. Identifying struggling students as early as possible could have a significant positive impact. If these students can be advised as early as possible, these students could be provided support and allowed to add or drop courses before it is too late. In the present work, we study the earliest student data in the semester, including the grades on the first homework assignments and first midterm exam. By leveraging actual student data, we develop predictive models of student success based on early homework and midterm scores. We have created models which predict with up to 86.7% accuracy whether a student will pass the data structures course, based on as little as the first homework assignment. These initial predictions could enable advisors to more rapidly and effectively support struggling students very early in the semester, improving a student's chances for success.


The article deals with a comparative study of indices of natural resistance in cow mothers and their daughters at the colostrums-lactic period. The indices of humoral and protein factors of resistance in cow-mothers and their offspring have been determined; the heredity coefficients (h2) of factors of natural resistance between related groups of animals have been calculated. The studies were conducted in the LLC «Demetra» Uvelsky district of Chelyabinsk region. The highest rate of heredity has been observed for such indices as the lysozyme activity, albumins, alpha-globulins, gamma-globulins, i.e. the above indices are hereditary dependent at 81, 62, 86 and 52 % respectively. The hereditary coefficients values indicate that when the process of selection in a dairy herd is based on selecting highly resistant cow-mothers there is a reliable opportunity to obtain an offspring that would be resistant to diseases.


The peritoneal tuberculosis is one of the differential diagnosis of ascites, but its documentation is provided by the presence of necrotizing granulomas as mycobacterial growth in samples taken from the peritoneum. This article presents the case of a patient with abdominal pain and ascites with the documentation of nodular lesions in the peritoneal cavity, with markedly elevated levels of "Carbohidrate Antigen o Cancer Antigen" CA 125, without changes in other organs. The peritoneum biopsies reports necrotizing granulomas and growth of mycobacteria in culture, then she received anti TB treatment with adequate response reducing the ascites' amount and earning weight.


A low power consumption and cheap remote surveillance system whose main MCU is W78E516B,is introduced.The software is developed based on the embedded operation system μC/OS-Ⅱ.The network works on the protocol chip of RTL8019AS.By this means,one can surveil this system by Web.CAN connects the main module and the controlled module.This design has many advantages such as simple structure,reliable work,simple route,lower cost and super performance.It can be used widely in remote surveillance system,unwatched transformer substation,safety and defense surveillance system,network home appliances,and so on.


In order to improve the motion stability and environmental adaptability of quadruped robot in trotting gait, a motion control method based on swing leg gait planning is proposed in this paper. The kinematics model of quadruped robot is established, the forward and inverse solutions are obtained, and the trajectory curve of swinging leg of quadruped robot in trotting gait is planned. The simulation model is established in ADAMS to verify that the trotting gait control method based on the foot trajectory planning of the swing leg is effective and feasible.


1. A double-blind study of reserpine (0.4 mg. per day) and placebo for angina pectoris in 18 city hospital out-patients is presented. Thirteen patients received both drugs in sequence. 2. The two groups of patients were similar in clinical and laboratory findings. 3. No significant difference in improvement of exercise tolerance, nitroglycerine requirement or both was observed between the two groups. 4. The failure of reserpine to be beneficial in angina pectoris in our series may be attributed to the low incidence of hypertension, the long duration of therapy, and the apparent inefficacy of this agent. 5. The difference in side effects was negligible, except for dizziness which was significantly more frequent in the reserpine group.


Two new species of Biantes Simon, 1885 (Biantidae: Biantinae) are described: Biantes calyptroideus sp. nov. (male and female) from China and Biantes spatulatus sp. nov. (male and female) from Malaysia. Biantidae is recorded from China for the first time.


Vertical velocity profiles and hydrography were intensively observed using Acoustic Doppler Current Profilers and CTD to understand the variation of baroclinicity over the spring-neap tidal cycle in the Sumjin River estuary, Korea. The Sumjin River estuary is a natural estuary in Korea. The river is 212km long, a drainage area is nearly 4,896km and the yearly mean discharge is 86.3m/s. The Sumjin River estuary experiences a transition from partiallyor well-mixed during spring tides (St < 0.15), but stratified conditions during neap tides (St > 0.32) based on the stratification parameter (St) which is the salinity difference between surface and bottom (δS) divided by the depth averaged salinity .


A complex filter is designed for a low-IF GPS receiver after analyzing the requirement of image signal rejection.This complex filter is based on OTA-C biquad structure and realized through linear translation.Full differential OTA with source degeneration is used to expand input linear range.A ring VCO based digital tuning loop is proposed to minimize frequency variation.The circuit is implemented in a 0.18μm CMOS process.Measured results show that the band width is 3.1MHz with 50dB out-of-band attenuation at 5MHz offset.Frequency tuning error is less than ±1.5%.Measured image rejection ratio is more than 35dB in the whole pass band.The filter and tuning circuit dissipate 0.82mA and 0.23mA under 1.8V power voltage,respectively.


— In the era of chatbots, besides imitating humans they can also perform complex tasks like booking tickets for movie etc. Out of various implementations, RASA is open source implementation for NLU and DIET model. It can interact with database, api, conversational flow, interactive learning with reinforcement Neural network. In this study, various features of rasa core are studied and upto much extent it can perform complex tasks. Implementation details are studied like interaction with database, API. Tracker Store has been examined with modifying the socket.io core file adding metadata to the user message data, so that user ip and port can be captured. Furthermore, the action, interactive learning and implementation details are tested on windows Pycharm IDE .


At the Savannah River Site (SRS), from 1958--1985, effluent waste from the reactor fuel and target rod fabrication area (M-Area) was discharged to a settling basin. In 1981, monitoring wells detected groundwater contamination, specifically trichloroethylene and tetrachloroethylene, in the immediate vicinity of the basin. Under the auspices of Resource Conservation and Recovery Act (RCRA) the M-Area contamination must be addressed by a corrective action program until the volatile organic compound (VOC) concentrations reach Drinking Water Standards. This was initiated in 1985 with startup of a full-scale pump-and-treat air stripper system. Recently, remediation efforts have focused on vacuum extraction to treat vadose zone contamination not addressed by the original recovery wells, and additional pump-and-treat systems to achieve hydraulic control of the plume. Regulatory requirements allowed for discharge of VOCs to the atmosphere when the original remediation system was installed; however, 1990 amendments to the Clean Air Act will eventually require treatment of VOC contaminated air prior to discharge. This has ramifications to systems currently being design, as well as the existing systems. In response to the 1990 Clean Air Act amendments, SRS initiated a study to assess commercially available off-gas treatment technologies. These included carbon adsorption, thermal incineration, catalytic oxidation, absorption,more » condensation, and UV/peroxide destruction, and xenon flashlamp. Criteria used to evaluate the technologies were the thirty (30) year life cycle cost, permitting considerations, and manpower requirements. The study concluded that catalytic oxidation provided the most desirable combination of these elements.« less


The dynamic mechanical properties of thermoplastic urethane elastomers have been compared for materials based on different diisocyanate structures, either 4,4′-diphenylmethane diisocyanate (MDI) or an isomeric ratio of tolylene diisocyanate (TDI). Two comparable series of polymers were prepared with a polycaprolactone diol as the soft segment and varying concentrations of hard segments based on the respective diisocyanates and 1,4-butanediol. Over the composition range studied, the polymer glass transition temperatures increased for the TDI-based polyurethanes, but remained relatively constant for the series containing MDI. Differences in the degree of macroscopic order within the hard segments, due to variations in the symmetry of the diisocyanate structures, are suggested as an explanation of these dynamic mechanical properties.


We herein report the complete characterization of the monoclonal Ig fragments produced by the plasma cell clone in a 65-year-old patient with a typical heavy chain deposition disease (HCDD).[1][1]–[3][2] The patient was referred for nephrotic syndrome and the main biological parameters are


The influence of the concentration of the solid phase and the flow rate of the flocculant on the change in the sedimentation rate of the solid phase and the strength of the floccules is studied. A technique is proposed for optimizing the parameters of aggregation and increasing the strength of floccules after hydromechanical influences, taking into account the concentration of the solid phase and the flocculant flow. It is found that the optimal conditions for aggregation can be achieved by minimizing the hydromechanical effects on floccules, as well as creating the best conditions for flocculation. Among the ways to optimize the process, the ways of influencing these factors due to the technological features of the introduction of the process are analyzed, such as concentration adjustment, transport rate of flocculed sludge, mixing time


The juvenile justice system in the United States has become a detrimental rather than a remedial experience, one that often reinforces youths' defiance of authority. Trying juveniles as adults, overcrowding juvenile detention facilities, and other factors have led to the deterioration of a system whose original intent was to protect immature youngsters who might get arrested for truancy or joyriding. The present system is ill equipped to cope with today's children who may be arrested for violent crimes such as rape and murder. "Balancing Juvenile Justice," now in an expanded, revised edition, is a comprehensive discussion of the primary considerations policymakers should use in striking a balance between holding youths responsible for past behavior, and providing services and opportunities so that their future behavior will be guided by constructive, rather than destructive, forces. The topics covered include: trends in philosophy and politics; a review of state and local reforms in juvenile justice; the changing role of the juvenile court; development of a balanced continuum of correctional programs; and strategies for reform. About the original edition, Perspectives on Political Science remarked. "This book contains a comprehensive discussion of the primary policy considerations that should be used in striking a balance between holding youths responsible for their past actions and providing for their welfare." Criminology noted that "the clear-eyed realism of this book is a welcome contribution to the too often shrill debate on the future of juvenile justice." Choice observed that, "Guarino-Ghezzi and Loughran have written a book that needs to be read not only by students in sociology and criminal justice but also by law students and legislators. This work sets forth some very real policy options for dealing with the vexing issue of juvenile law violators."


We consider the class of all the Hermite processes $(Z_{t}^{(q,H)})_{t\in \lbrack 0,1]}$ of order $q\in \mathbf{N}^{\ast}$ and with Hurst parameter $% H\in (\frac{1}{2},1)$. The process $Z^{(q,H)}$ is $H$-selfsimilar, it has stationary increments and it exhibits long-range dependence identical to that of fractional Brownian motion (fBm). For $q=1$, $Z^{(1,H)}$ is fBm, which is Gaussian; for $q=2$, $Z^{(2,H)}$ is the Rosenblatt process, which lives in the second Wiener chaos; for any $q>2$, $Z^{(q,H)}$ is a process in the $q$th Wiener chaos. We study the variations of $Z^{(q,H)}$ for any $q$, by using multiple Wiener -It\^{o} stochastic integrals and Malliavin calculus. We prove a reproduction property for this class of processes in the sense that the terms appearing in the chaotic decomposition of their variations give rise to other Hermite processes of different orders and with different Hurst parameters. We apply our results to construct a strongly consistent estimator for the self-similarity parameter $H$ from discrete observations of $Z^{(q,H)}$; the asymptotics of this estimator, after appropriate normalization, are proved to be distributed like a Rosenblatt random variable (value at time $1$ of a Rosenblatt process).with self-similarity parameter $1+2(H-1)/q$.


The nobility of solid polymer electrolyte (SPEs) has made them a subject of interest, especially in the arena of science and technology, and most importantly as they are used as separators in industries and by researchers for the assembly of some "few battery types" and supercapacitors. This paper, highlights the nobility of the hybrid solid polymer electrolyte (HSPE), particularly at room temperature such that, it can be used as an electrolyte as well as a separator in supercapacitor fabrication. The hybrid SPEs were produced from the composition of polyvinyl alcohol (PVA) and Phosphoric acid (H 3 PO 4 ), where the PVA samples were kept constant while the phosphoric acid concentration was varied at 0, 10, 20, 30, 40, 50, 60, and 70 wt. %. XRD results show that, the crystallinity decreases as the acid concentration increases and consequently, there is an enhancement in the amorphicity of the samples responsible for the process of ion transport. This characteristic behavior was confirmed by the analysis of the differential scanning calorimetry results. FESEM result pictured the entangling nature of the combined samples. High conductivity of 1.67 x 10 -3. Scm -1 was recorded for the HSPE at the composition of 70:30 wt. %. It was also noticed that, the bulk modulus, R b of the HSPE (5.73 ?) at the aforementioned composition decreases with the increase in concentration.


There is an increasing awareness that knowledge of the functional diversity of a community is key to understand how the community responds to environmental and anthropogenic stressors. It is also expected that indicators derived from biological traits could be more suitable to quantify the sensitivity of benthic communities and can be used to detect changes in ecosystem functioning within environmental impact assessments. The Belgian Part of The North Sea (BPNS) represents a highly dynamic area that is subject to a variety of human activities. Within this study, three different physical impacts -dredge disposal, sand extraction and offshore wind energy– were used to assess differences in functional diversity of macrobenthos communities between impactand reference areas.


This paper presents a model for simulating realistic crowd behaviors at low computation cost. The proposed model is inspired by video data. In our approach, we first classify the crowd into two categories: main and background characters. Whether the agents are main characters or not is influenced by two factors, one is the agent's trajectories and the other one is the change of the environment. In the second stage, we adopt two approaches to simulate the behaviors of main and background characters. Main characters are intelligent agents with the perception, the memory, the planning, and the psychology so that they can make decisions themselves. Background characters are informed of the behavior options for execution by the "smart environment." Finally, we simulate the road‐crossing scenario in a three‐dimensional virtual environment. The experimental results demonstrate that our approach not only well reflects the characteristics of agent behaviors but also reduces the computation complexity of simulating realistic crowd. Copyright © 2013 John Wiley & Sons, Ltd.


To solve the problems of a cross-training plan for staffs in a flexible assembly cell from the point of views of humanization and economy,a multi-objective optimal cross-training plan is proposed.Average labor satisfaction and average task payment are chosen as the goals of the model,and the multi-functionality and task coverage policies are used as the constraints.To solve the multi-objective optimal model,the non-dominated sorting genetic algorithm-II based on double terminated rules and Pareto filter techniques is proposed.Simulation results show that this algorithm improves the operation efficiency and diversity of the Pareto solutions.


This review examines the research evidence for cognitive deficits in first episode psychosis (FEP), their neurological basis and their relation to social functioning. Twenty-six papers were identified by searching computer databases (e.g. PsycINFO, the Cochrane Library, etc.), hand searching relevant journals, and searching reference sections of key papers. The papers identified were then categorised into 3 subject areas: neurological, cognitive deficits, and social ftinctioning. FEP patients showed an excess of neurological soft signs and differences in brain morphology compared to healthy controls. While there appears to be clear evidence to support a generalised cognitive deficit in FEP, there may also be a sub-group of patients who have specific impairments in some aspects of cognitive function. There appears to be little or no evidence of an association between cognitive deficits and social functioning in FEP, though this area requires further research in the future.


With the rapid development of communication technologies and extended reality (XR), the services and applications of the Metaverse are gradually entering our lives. However, the current development of the Metaverse provides users with services that are homogeneous with the user experience that the Internet has brought in the past, making them more like an extension of the Internet. In addition, as a mobile application carrier for the Metaverse, it is also worth considering how vehicles with diverse onboard components can develop in synergy with the Metaverse. In this article, we focus on the core of the Metaverse, namely user experience, and provide a road map from Metaverse to Metaverse vehicles (Metavehicles). Specifically, we first elaborate on six features of the Metaverse from the perspective of user experience and propose a hierarchical framework for the Metaverse based on the evolutionary logic of the features. Under the guidance of this framework, we discuss the empowerment of onboard components of Metavehicles on the development of the Metaverse, and analyze the service experience that Metavehicles can bring to two types of users, namely drivers and passengers. Finally, considering the differentiated development levels of Metaverse and autonomous driving, we further establish a hierarchical framework for Metavehicles from three aspects (i.e., enhance Metaverse, enhance driving experience, and enhance entertainment experience), providing an evolutionary path for the development of Metavehicles.


The Interior point method in linear programming is classified into two categories the affine-scaling method and the logarithmic barrier method. In this paper, we integrate those methods and implement them in one shared module. First, we analyze the procedures of two interior point methods and then find a unified formula in finding directions to improve the current solution and conditions to terminate the procedure. Second, we build the shared modules which can be used in each interior point method. Then these modules are experimented in NETLIB problems.


One of the major factors determining economic development is Entrepreneurship. It has been found that the higher the Entrepreneurship in any economy, the greater is the economic development. GEDI is a good indicator of the level of entrepreneurship in any economy. Based on the GEDI it has been seen how developed countries are having a high Global entrepreneurship Development Index. Economies should therefore strive to put a strong emphasis on entrepreneurship as a key to development. In order to achieve this, developing countries should find ways to encourage entrepreneurship and this paper attempts to trace the stages of entrepreneurship development and also suggests measures that can lead an economy to success in this crucial area of development.


We have investigated, by on-the-fly path integral molecular dynamics (PIMD) simulations, which can take into account the nuclear quantum and thermal effects, the nuclear quantum effect on the muoniated ethyl radical, where one of the hydrogen atoms of the methyl group in the ethyl radical is substituted with a muonium. Muonium consists of a positive muon and an electron, which can be considered as an ultra-light isotope of a hydrogen atom, and we here focused on the muon spin resonance/rotation/relaxation (μSR) and the hyperfine coupling constants (HFCC). Our PIMD simulation with the semiempirical PM6 method has succeeded in treating the nuclear quantum effect, which results mainly in the elongation of the bond length and the characteristic rotation of the CH2Mu group. Our PIMD simulation provides dramatic improvements in the characteristics of the HFCCs obtained from the conventional PM6 calculation, although the calculated HFCCs are not in qualitative agreement with the corresponding experimental ones because of the limitation of the semiempirical PM6 method for systems with an unpaired electron.


In March 1924, French author André Gide opened his journal and jotted down a few thoughts about the theories of his compatriot, the then world-famous philosopher, Henri Bergson. He predicted that, because Bergson was so representative of his own time period, future historians would exaggerate the influence he had on his contemporaries. It is hard to imagine nowadays that Bergson was once one of the most famous intellectual figures in the world, discussed in philosophical, literary, religious, political and scientific communities, but also outside of intellectual circles. His lectures at the Collège de France were so crowded that people had to resort to climbing up the side of the building of the prestigious Parisian institution; a conference he gave, in French, at Columbia University in 1913 caused one of the first ever traffic jams on Broadway. Bergson engaged with the scientific theories of his time, ranging from psychology to biology and physics. However, as Jimena Canales shows in The Physicist and the Philosopher, if there is any truth to Gide's prediction it is not to be found in the history of science, where little attention has been paid to the reception of Bergson's theories within scientific communities. Scholars interested in Einstein's life and work have rarely given much importance to the event at the centre of Canales's book: his meeting with Bergson at the Société française de philosophie in Paris on April 6, 1922. After declining several times, Einstein finally accepted an invitation to deliver a talk about his theory of relativity before the crème de la crème of French philosophers. During the questions following the talk, Bergson was unwillingly drawn into the discussion. The philosopher insisted that Einstein's theory did not tell the whole story about time and that there was still room for a philosophical discourse beyond physics. Science proposed a convenient symbolism for representing time but never revealed its true nature. Einstein's response was short but scathing: 'The time of philosophers does not exist'. Einstein believed his theory to be an objective account of time. Subjective appreciations of time also existed but were the concern of psychologists, not physicists. There was no room, however, for Bergson's metaphysical time, 'duration'. Einstein went down in history as having won the debate. However, as is almost always the case, meticulous research like the kind demonstrated by Canales reveals that the received narrative doesn't do justice to the complexity of the situation. The four parts of the book zoom in and out, from the individuals to their environment, and back and forth in time. Canales opens with Einstein and Bergson's first meeting and closes on some of their final words at the end of their lives, with both men reflecting on the significance of their dispute. The second and third parts deal respectively with the different thinkers involved ('The Men') and their environment ('The Things'). Canales first covers the propagation of the debate beyond the Société française de philosophie and beyond the borders of France, with intellectuals, religious figures and scientists taking sides. The debate spread to the


ABSTRACT In this study, a sampled-data nonlinear model predictive control scheme is developed. The control algorithm uses a prediction horizon with variable length, a terminal constraint set, and a feedback controller defined on this set. Following a suboptimal solution strategy, a defined number of steps of an iterative optimisation routine improve the current input trajectory at each sampling point. The value of the objective function monotonically decreases and the state converges to a target set. A discrete-time formulation of the algorithm and a discrete-time design model ensure high computational efficiency and avoid an ad hoc quasi-continuous implementation. This design technique for a fast sampled-data nonlinear model predictive control algorithm is the main contribution of the paper. Based on a benchmark control problem, the performance of the developed control algorithm is assessed against state-of-the-art nonlinear model predictive control methods available in the literature. This assessment demonstrates that the developed control algorithm stabilises the system with very low computational effort. Hence, the algorithm is suitable for real-time control of fast dynamical systems.


A new truffle species, Tuber huidongense, collected from Huidong in SW China is described and illustrated. This new species is apparently mycorrhizal with Pinus yunnanensis or P. armandii. The relationship of the new species to other closely related species is discussed.


The authors make a theoretical study of the excitation of a monochromatic plasma wave by a modulated electron beam in an inhomogeneous plasma when synchronism is kept up between the beam and the excited wave. Results are also given of experimental studies on the interaction of a modulated beam with a homogeneous and an inhomogeneous plasma.


This work deals with a study on the effect of the deformations in flexiblocks (bushings) on the behavior of the vehicle axle suspension mechanisms. The mechanism in study is a representatiove one for the structural group/class of mono-mobile axle suspension systems, namely the guiding mechanism by five points - on five spheres (so called 5SS). In a previous work, it was established that the rigid joint model for this class of mechanisms does not provide results close to the real flexible bushing model, reason for which the research in this paper is directed towards the identification of a theoretical model of joint which, at a lower complexity than that of the real model, would still provide viable results, in terms of axle guidance accuracy in the spatial movement relative to car body. In this regard, static and kinematic models were developed and analyzed by using the MBS (Multi-Body Systems) software solution ADAMS.


The structural, magnetic, and magnetotransport properties of ${\text{SrRuO}}_{3}$ films grown on ${\text{SrTiO}}_{3}$ (001) substrates were investigated with the aim to determine the crystalline symmetry, crystalline orientation, and magnetocrystalline anisotropy of an ultrathin (5 nm) ${\text{SrRuO}}_{3}$ film. 60- and 40-nm-thick ${\text{SrRuO}}_{3}$ films were extensively studied by transmission electron microscopy as well as magnetic and magnetotransport techniques, respectively. These studies showed orthorhombic symmetry with a slight monoclinic distortion and a well-defined long-range order of crystallographic domains with the ${[001]}_{o}$ axis parallel to terraces on the slightly vicinal ${\text{SrTiO}}_{3}$ substrate. The magnetocrystalline anisotropy is very strong. The easy axis lies in the ${(001)}_{o}$ plane under a temperature-dependent angle of about $35\ifmmode^\circ\else\textdegree\fi{}$ with respect to the ${[110]}_{o}$ direction that is along the film normal. Below 70 K indications for a spin reorientation transition were detected. The angular-dependent anisotropic magnetoresistance shows distinctive characteristics of the monoclinic symmetry that can be used as a fingerprint. Transmission electron microscopy images of the 5 nm thin ${\text{SrRuO}}_{3}$ film show a coherently strained state. Using the fingerprints from the angular magnetoresistance it could be clearly shown that this ultrathin ${\text{SrRuO}}_{3}$ film, although grown in step flow growth as well, has still monoclinic symmetry, but lacks long-range order of the crystallographic domains. A fraction of $30\char21{}40\text{ }\mathrm{%}$ of misaligned domains (rotated in plane by $90\ifmmode^\circ\else\textdegree\fi{}$) was estimated from the magnetoresistance curves.


The present invention is a non-isolated multi-phase DC-DC converter suitable for high boost fuel cell applications. In the current continuous mode, the switch is capable of zero voltage switching turn-on and the diode is operated by reverse current recovery by zero current switching turn-off operation. Eliminates voltage, selects the number of parallel inputs and outputs of inputs and outputs, making it easy to choose the price and availability of components available for high power and high voltage applications, reducing the voltage ratings of all devices and the volume of passive devices. have.


The first case of soft tissue Ewing's sarcoma in Greece is presented. The tumour was a circumscribed large mass at the right calf, was radically excised and histologically proved to be small cell malignant neoplasm, performing the characteristic structural and cytological pattern of Ewing's sarcoma. Systematic clinical and radiological examination was negative. Operation was followed by local radiotherapy and systematic chemotherapy and the patient remains disease‐free and clinically in perfect health eight months after the operation. The case is presented with special reference to its histological appearance and its treatment.


We present a highly sensitive miniaturized cavity-enhanced room-temperature magnetic-field sensor based on nitrogen-vacancy (NV) centers in diamond. The magnetic resonance signal is detected by probing absorption on the 1042\,nm spin-singlet transition. To improve the absorptive signal the diamond is placed in an optical resonator. The device has a magnetic-field sensitivity of 28 pT/$\sqrt{\rm{Hz}}$, a projected photon shot-noise-limited sensitivity of 22 pT/$\sqrt{\rm{Hz}}$ and an estimated quantum projection-noise-limited sensitivity of 0.43 pT/$\sqrt{\rm{Hz}}$ with the sensing volume of $\sim$ 390 $\mu$m $\times$ 4500 $\mu$m$^{2}$. The presented miniaturized device is the basis for an endoscopic magnetic field sensor for biomedical applications.


Primordial germ cells (PGCs) are the progenitors of the gametes, responsible for transmitting genetic information from generation to generation. Although there is a long history of gamete biology research, there is still a lot to be learned about many of the mechanisms underlying germ cell development. This dissertation describes and discusses the dynamics of PGCs in the chicken, with a focus on their migration to the gonads and meiosis that takes place when PGCs are already settled there. We also discussed the advantages of using the avian model in epithelial ovarian cancer research. Moreover, we revisited an often overlooked model for amniogenesis in which the proamnion plays a crucial role.


The contribution to the extragalactic background from clusters of galaxies in the 2-6 keV band was computed. Two different cluster luminosity functions and two different models for cluster evolution were considered and a cluster X-ray luminosity-temperature relationship of the type L alpha T sup alpha +1/2 was assumed. It is found that the overall contribution of clusters to the background is approximately 10% of the total observed X-ray extragalactic approximately 150 eV is superimposed on the observed background. This result is quite insensitive to the different set of assumptions made in the calculation.


Somatic mutations in FAT cadherin family members constitute an underrecognized subtype of colorectal after natural orifice extraction vs conventional specimen extraction surgery for colorectal cancer: A propensity score-matched analysis Abstract The inflammatory response to tumor has been proven to be closely related to the prognosis of colorectal cancer. Neutrophil to lymphocyte ratio (NLR) is a widely available inflammatory biomarker that may have prognostic value for patients with colorectal liver metastasis (CRLM). To assess the role of NLR as a prognostic factor of survival and tumor recurrence in patients with CRLM. Liver metastases were treated with hepatectomy with or without chemotherapy regimens in 13 studies and with radiofrequency ablation, radioembolization, chemoembolization or solely with chemotherapy in 6 studies. High NLR was associated with decreased OS and DFS after liver resection or other medical intervention. Moreover, high NLR was associated with poor chemosensitivity. On the contrary, CRLM patients with low pretreatment NLR demonstrated improved OS and DFS. NLR could potentially be used as a predictive factor of survival and tumor recurrence in patients with CRLM treated with interventions of any modality, including surgery, chemotherapy and ablative techniques. biomarker that demonstrates considerable prognostic are to discussion between and a third reviewer. The following data were extracted from each study: (1) Patients' clinicopathological characteristics; (2) The treatment modalities used to treat CRLM; (3) The median survival, and OS, and 5-year DFS; and (4) The univariate and multivariate analysis outcomes. Our results clearly demonstrate that elevated NLR is associated with adverse OS and DFS. These results are significant and they are the same across heterogeneous studies that included different populations, age groups, cancer stages, chemotherapy regimens and medical interventions, which shows that NLR could be an important prognostic factor that can be used in CRLM patients. High pretreatment NLR is associated with worse outcomes independently of the treatment received by the patients.


In many medical conditions 'late presentation' of disease is more of a problem for men than women. Risk of sight loss from glaucoma is certainly greater in those detected with advanced disease. We performed a retrospective study to test the hypothesis that men are more likely than women to have advanced visual field loss at referral to glaucoma clinics.


The feasibility of constructing large arrays of wind turbines (100-1000 machines) has now been firmly established. The energy losses are predictable, and can be kept below 20-25% with suitable choice of spacing. The energy yields of clusters have been calculated so as to quantify the UK offshore windpower resource, and estimates have also been made as an input to assessments of the problems and costs of both onshore and offshore siting. Plans for construction of arrays have now been announced by a number of electricity supply authorities, including the CEGB. Provision of performance prediction data for these arrays, particularly the smaller ones, will necessitate development of existing techniques to take into account the operating characteristics of particular machines. The procedures are illustrated using the specific example of the Nibe cluster, where wake measurements are currently being made, and the annual energy loss for this cluster is estimated at 3%. It is concluded that spacings can be reduced with fewer machines: from the 10-12 rotor diameters applicable in large arrays down to five diameters, as at Nibe, with, say, two-four machines. The requirements for further analytical and experimental studies are discussed, with particular reference to the current UK programme, but also, where appropriate, to studies being carried out elsewhere. Data on the wakes and interactions of large machines are needed, especially for comparison with estimates derived from the predictive techniques. An assessment of the limited data currently available confirms, qualitatively, the value of corroborative studies at model scale, but points to the need for a more detailed understanding of the mechanisms of wake generation and decay.


Why do commodity-dependent developing countries have typically lower levels of financial development than their peers? The literature has proposed many possible explanations, but it typically does not dwell on the deep mechanisms that drive such an outcome. In this paper, we argue that one of the main causes is the shocks to commodity prices. We test the hypothesis on 68 commodity-rich developing countries over the period 1980–2014, and we find strong evidence of the financial development resource curse through the channel of commodity price shocks, after controlling for other explanations found in the literature. The findings are robust to the different types of commodities, the nature of the shocks, various indicators of financial development, and alternative econometric methods. We also show how the impact of these shocks can be mitigated through good quality of governance. JEL Classification Numbers: E30, E44, G38.


GUHPFRC Fly Ash Steel Fibers Experimental Work. Nowadays, producing eco-friendly concretes by reducing the usage of high volumes of Portland cement is a global aim. Ultra-High Performance Fiber Reinforced Concrete (UHPFRC) involve using high volumes of Portland cement, which leads to high heat of hydration as well as high carbon emissions that enhance global warming. Therefore, researchers worldwide are interested in producing and assessing Green Ultra-High Performance Fiber Reinforced Concrete (GUHPFRC) which is the main focus of this paper. In this study, thirteen mixtures of such concretes are prepared to study the effect of using Fly Ash (FA) class F, as a Portland cement substitute by volume. The Fly Ash ratios of 15%, 30% and 45% are used to study the effect on the compressive strength of UHPFRC. The paper also focuses on incorporating both corrugated and end hook steel Fibers in the mixes with ratios (1%, 2%, 3% and 4%) to compensate for the decrease in compressive strength of concrete due to the replacement of cement by FA. The results showed that the substitution of 45% of the Portland cement with FA along with the incorporation of steel Fibers in the UHPFRC can be effective without any compressive strength loss.


A number of processes are possible in the interactions of positrons with atoms and ions. These are scattering from various targets, formation and annihilation of positronium atoms, bound states, and resonances. Calculations of these processes, using different methods, are described. Scattering of positronium atoms from various targets is discussed. Positronium beams can be produced by the photodetachment of negative positronium ions. Calculations of cross sections by two different methods are indicated.


A b s t r a c t Methods, planning, and strategies have represented three distinct phases of didactic and pedagogic research. Current trends tend to focus once again on the importance of the teacher, and give preference to procedures that help pupils grasp the significant elements of the teaching contents. Current didactic strategies include Rogers' "non-directive learning", "research-action" "teaching to think"; "problem solving" Ausubel's "bifactorial teaching-learning" model; and more recent strategies such as the Bruner-inspired "meaningful teaching" and "peer education" (a sort of mutual teaching between peers, or between older and younger children). Each of these strategies has aspects that are different from the others. More generally, each one of them stands in opposition to transmissive teaching, which forces pupils into a passive condition and imposes mnemonic learning. The most extensive research on this issue was conducted in the field of mathematics teaching and dates back to the 1980s. This research has highlighted the fact that the key condition for a successful outcome is the direct classroom work carried out by the Teacher, and not the procedure in and of it self. There are a wealth of experiences and suggestions in this regard. The teacher must take on the role of mediator, guide, or learning facilitator; this role should include suggestions, reports, reprimands, and demonstrations along with overall and initial teaching units, and should constantly provide tools for re-structuring the knowledge that has gradually been acquired. It must also avail itself of the art of "problem solving" and the ability to frame a problem, formulate new conjectures, and add variables. However, it would be mistaken to contrast heuristic and transmissive teaching strategies. Another thesis which needs to be revised is that which maintains that a good strategy, in order to be successful, must establish links with a pupil's life experience; on the contrary, pupils need to be able to think through problems that are not related to their experiences.


This paper is concerned with the adaptive numerical treatment of stochastic partial differential equations. Our method of choice is Rothe's method. We use the implicit Euler scheme for the time discretization. Consequently, in each step, an elliptic equation with random right-hand side has to be solved. In practice, this cannot be performed exactly, so that efficient numerical methods are needed. Well-established adaptive wavelet or finite-element schemes, which are guaranteed to converge with optimal order, suggest themselves. We investigate how the errors corresponding to the adaptive spatial discretization propagate in time, and we show how in each time step the tolerances have to be chosen such that the resulting perturbed discretization scheme realizes the same order of convergence as the one with exact evaluations of the elliptic subproblems.


Balkan endemic nephropathy (BEN) is a devastating tubulointerstitial kidney disease affecting men and women living in rural areas of Bosnia–Herzegovina, Bulgaria, Croatia, Romania and Serbia [1]. The disease occurs exclusively in farming villages situated in valleys of the Danube River and its tributaries. Since its first description in 1956, the geographic distribution as well as other epidemiologic features have remained constant, including its focal occurrence in certain villages, its familial but not inherited character, the initial manifestation after residence in an endemic village for 15 years or more and the strong association with urothelial malignancies of the upper urinary tract. Despite the extensive research on the aetiology of BEN and the accompanying urothelial tumours, elegantly summarized by Stefanovic and co-workers in a recent review published in the American Journal of Nephrology [2], the cause of the disease remained a medical enigma. During the past 50 years both genetic factors and environmental factors including viruses, heavy metals, trace element deficiencies, mycotoxines (ochratoxin A), plant toxins (aristolochic acid) and polycyclic aromatic hydrocarbons from coal deposits (Pliocene lignite) have been proposed as possible aetiologic factors. The hypothesis that aristolochic acid (AA), a nephrotoxic and carcinogenic plant alkaloid derived from Aristolochia species, could be a potential aetiologic factor for BEN was formulated as early as the 1970s, based on epidemiologic, environmental and agricultural research [3]. It was observed that Aristolochia clematitis, a plant native to the endemic


A method of controlling resources common Enhanced Dedicated Channel, E-DCH - Dedicated Channel Enhanced in a base station radio (101) characterized in that the method comprises the steps of: - receiving (201) a preamble to access one of common E-DCH resources from a User Equipment, UE - User Equipment in the CELL_FACH state. - return (203, 205, 207) the UE a negative acknowledgment, NACK - Negative Acknowledgment, if the default resource for the received preamble is free and at least one resource is free.


OF THE DISSERTATION REAL-TIME SCHEDULING OF EMBEDDED APPLICATIONS ON MULTI-CORE PLATFORMS by Ming Fan Florida International University, 2014 Miami, Florida Professor Gang Quan, Major Professor For the past several decades, we have experienced the tremendous growth, in both scale and scope, of real-time embedded systems, thanks largely to the advances in IC technology. However, the traditional approach to get performance boost by increasing CPU frequency has been a way of past. Researchers from both industry and academia are turning their focus to multi-core architectures for continuous improvement of computing performance. In our research, we seek to develop efficient scheduling algorithms and analysis methods in the design of real-time embedded systems on multi-core platforms. Real-time systems are the ones with the response time as critical as the logical correctness of computational results. In addition, a variety of stringent constraints such as power/energy consumption, peak temperature and reliability are also imposed to these systems. Therefore, real-time scheduling plays a critical role in design of such computing systems at the system level. We started our research by addressing timing constraints for real-time applications on multi-core platforms, and developed both partitioned and semi-partitioned scheduling algorithms to schedule fixed priority, periodic, and hard real-time tasks on multi-core platforms. Then we extended our research by taking temperature constraints into consideration. We developed a closed-form solution to capture temperature dynamics for a given periodic voltage schedule on multi-core platforms,


This paper presents age estimation of school-age children from dual-task behavior, which is known to be affected by cognitive ability. By observing a school-age participant performing the dual-task with Kinect and other sensors, our dual-task experience system measures his/her anthropometric, kinematical, and cognitive aspects of information simultaneously. We collected observations of more than a thousand school-age children, applied regression for estimating ages from each aspect and all of them, and discussed their differences. As a result, we found that age estimation using the all aspects is the best. This fact indicates that our age estimation could be useful for comprehensive growth assessment of children.


This paper deals with determining the maximal regions within the Wrench-Feasible Workspace (WFW) of cable-driven parallel robots using convex optimization. In this regard, an approach is proposed in order to obtain the maximal-area ellipse and the maximal-volume ellipsoid within the wrench feasible workspace of the planar and spatial cable-driven parallel robots respectively, using convex optimization. The main contribution of this paper consists in relaxing the equations of the workspace boundaries by using Weierstrass and Chebyshev approximation theorems, which are approximated to the higher-order workspace equations with second-order polynomials. Then, an algorithm to solve the obtained quadratic programming problem is introduced. Finally, a pseudo-code for the proposed procedure is presented and the obtained results are illustrated.


The military coup of February 1, 2021 ended Myanmar's nominal transition to democracy. That transition had begun with the 2010 election under the military-drafted 2008 Constitution. The coup and post-coup Myanmar's crises are the tip of the iceberg of a long endured political crisis about how to build an inclusive political system that respects the ethnic, cultural, and religious diversity of Burmese society at large. This article argues that the 2021 military coup itself may be a much-needed event for the future history of Burma: the coup has provoked resistance across ethnicity and religion to an unprecedented level.


Reducing carbon leakage is one of the important reasons that was put forward by the EU for their border adjustment tax proposal. However, there are not many empirical evidences supporting significant carbon leakage in the EU carbon-intensive industries. This paper applied the structural breakpoint test for the time series of import and export of cement, aluminum, and steel between EU and China. No significant structural changes were detected in the import and export of cement and aluminum. However, there proved to be two breakpoints, i.e., 2003 and 2008, in the import and export of steel, in which at the second point the overall level of steel import increased. Furthermore, Granger causality test was applied to the carbon price from European Climate Exchange and the import and export of steel. It was found that the carbon price was the Granger cause for the changes of steel import, but not the Granger cause for the export. The results of the study showed that the impacts of EU ETS on the EU carbon-intensive industries were limited. Among the three industries, partial evidence of carbon leakage was only found in the steel industry. Therefore, reducing carbon leakage could not serve as a convincing justification for border adjustment tax.


A new fuel pump calibration method was proposed in terms of performance characteristic of fuel pump of diesel/CNG dual fuel engine,in which cycle fuel and uniformity per cylinder cycle fuel were controlled strictly when the pump rack displacement was smaller.A fuel pump was calibrated applying this new method.The effects of this fuel pump on the combustion cycle variability and emission in a dual fuel engine were investigated.The results show that,after using the fuel pump with new calibration method,the combustion cycle variability decreased to a great extent,the NO_x exhaust emission improved obviously,and the engine performance stability increased.


We show possible transverse-momentum-dependent parton distribution functions (TMDs) for spin-1 hadrons including twist-3 and twist-4 functions in addition to the leading twist-2 ones by investigating all the possible decomposition of a quark correlation function in the Lorentz-invariant way. The Hermiticity and parity invariance are imposed in the decomposition; however, the time-reversal invariance is not used due to an active role of gauge links in the TMDs. Therefore, there exist time-reversal-odd functions in addition to the time-reversal even ones in the TMDs. We list all the functions up to twist-4 level because there were missing terms associated with the light cone vector $n$ in previous works on the twist-2 part and there was no correlation-function study in the twist-3 and twist-4 parts for spin-1 hadrons. We show that 40 TMDs exist in the tensor-polarized spin-1 hadron in twists 2--4. Some expressions of twist-2 structure functions are modified from previous derivations due to the new terms with $n$, and we find 30 new structure functions in twists 3 and 4 in this work. Since time-reversal-odd terms of the collinear correlation function should vanish after integrals over the partonic transverse momentum, we obtain new sum rules for the time-reversal-odd structure functions, $\ensuremath{\int}{d}^{2}{k}_{T}{h}_{LT}=\ensuremath{\int}{d}^{2}{k}_{T}{h}_{LL}=\ensuremath{\int}{d}^{2}{k}_{T}{h}_{3LL}=0$. In addition, we indicate that new transverse-momentum-dependent fragmentation functions exist in tensor-polarized spin-1 hadrons. The TMDs are rare observables to find explicit color degrees of freedom in terms of color flow, which cannot be usually measured because the color is confined in hadrons. Furthermore, the studies of TMDs enable us not only to find three-dimensional structure of hadrons, namely, hadron tomography including transverse structure, but also to provide unique opportunities for creating interesting interdisciplinary physics fields such as gluon condensates, color Aharonov-Bohm effect, and color entanglement. The tensor structure functions may not be easily measured in experiments. However, high-intensity facility such as the Thomas Jefferson National Accelerator Facility, the Fermilab Main Injector, and future accelerators like electron-ion collider may probe such observables. In addition, since the Nuclotron-based Ion Collider fAcility focuses on spin-1 deuteron structure functions, there is a possibility to study the details of polarized structure functions of the deuteron at this facility.


l Introduction. This article was motivated by the desire to obtain an iterative method for solving a system of equations, linear or not, into which all equations would enter symmetrically, and which would be suitable for numerical application, particularly on a high speed digital computing machine. The general problem considered is the solution of a system of k equations {/j(a?)=O} in n unknowns (xlf •••, xn)=x where, as throughout the paper, all variables and function values are real. Each step of our method consists in obtaining, from one approximation a; to a solution of the system, the next approximation by adding to x the vector sum of corrections parallel to the gradients of the k functions f5(x). The lengths of the corrections are regulated by individual weights and by use of a factor ^=£0. The component gradient correction for a single equation //#)=0 is of the Newton-Raphson type because the correction, if applied to an initial approximation #, gives a point annihilating the usual linear approximation to fό{x) for x near # . After considering in § 2 the well known formula for a gradient correction to an approximate solution # of a single equation f(x)=0, the method of composite gradient corrections for a general system is described in § 3. In § 4, we apply the method to a system of k linear equations in n unknowns, and prove that, for an arbitrary approximation # to a solution of the system, we obtain a sequence {#} which tends with a geometric rate of convergence to a point x, nearest to #, of the set which satisfies the system in a sense of weighted least squares. Section 5 treats a fairly general system with an isolated solution x. The sequence {#} of § 3 is proved to converge to x if the initial approximation # is sufficiently near x. Section 6 considers the implicit function x=x(t) defined by a related system of n equations f(x; r)=0, where τ=(τlf * ,rΛ), and τ=r(ί), 0<[£<Il. It is proved that, if O=to<Ct1<C* ' <itι=l is a fine enough partition of the ^-interval, then the sequence {#} of § 3 tends to x(tt) if ίc (0)=^(ίί_.1) This result yields a small arc method for computing the points x{tt) in sequence. There is an extensive literature on the solution of linear systems {fj() = Q} by iterative processes where each iteration involves a correction related to a specified direction, in particular that of some gradient;


Objective
To explore the influence of gender, age and types of peer acceptance on the ability of theory of mind among rural parent-absent children.

Methods
312 rural parent-absent children participated in the study (including 162 boys, 150 girls; 102 members of 8 year-old, 119 members of 9 year-old, and 91 members of 10 year-old). Their ability of theory of mind and types of peer acceptance were examined by the 2nd-order False-beliefs Tasks and Peer nomination. The date were analyzed by Multivariate analysis of variance (ANOVA), LSD checkout and Simple effect analysis.

Results
There were statistically significant effects on ages in theory of mind, types of peer acceptance(F=4.57, P=0.011; F=3.82, P=0.005)and the interaction among gender, ages and types of peer acceptance(F=3.20, P=0.042; F=2.50, P=0.043). The least significant different( LSD) assay of the ability of theory of mind age and types of peer acceptance shows: there were statistically significant lies in the divergence of age 8 and age 9 group, and also in age 9 and age 10 group, (I-J=-0.51, P=0.016; I-J=-0.90, P=0.000). In the same way, there were also statistically significant lies in the divergence of the ability of theory of mind performance-popular and rejected (I-J=1.05, P=0.001); popular and neglected (I-J=0.84, P=0.003); popular and controversial(I-J=1.03, P=0.002); rejected and average (I-J=-0.66, P=0.02); controversial and average (I-J=-0.64, P=0.034). Results of simple effect shows: there were statistically significant lies in the gender divergence of the 9 age group(F=4.98, P=0.026), the age divergence of girls(F=7.50, P=0.001), the gender divergence of controversial groups(F=5.76, P=0.017), the peer acceptance divergence of boys(F=4.97, P=0.001), and also the peer acceptance divergence of girls(F=2.54, P=0.04).

Conclusion
There is substantial connection between the ability of theory of mind of rural parent-absent children and ages and types of peer acceptance.

Key words:
Theory of Mind; Rural parent-absent children; Peer acceptance


Superplasticiser (SP) is now an indispensable ingredient for the production of concrete. However, its proper use is a great concern because its over-dosage could lead to drastic reduction in the cohesiveness of concrete. Furthermore, experience has indicated that the SP demand, saturation dosage and dosage causing segregation are highly dependent on the powder content and therefore the effects of SP are not simple functions of dosage. This study aims to evaluate the effects of SP dosage on the fresh properties of cement paste containing condensed silica fume (CSF). A number of cement paste samples with different SP dosages and CSF contents were tested. The results showed that the addition of SP would improve the packing density, flowability and rheology but impair the cohesiveness of cement paste. It would also render the cement paste shear thickening. To cater for the effects of powder fineness, it is proposed that the SP dosage should be measured in terms of the quantity of SP per surface area of the po...


Each person carries digital devices that communicate with other person's devices and may transmit sensitive data. When the transmitted data is sensitive, it becomes necessary to implement secure mechanisms to hide the information and thus avoid it from being analyzed by third parties. This paper aims to present Ncryptr, a web-based application that allows its users to exchange encrypted instant messages in real time. Outside parties are unable to extract the contents of the messages exchanged between two or more users. Ncryptr allows its users to choose the type of encryption employed, being this a major distinction with others already existing instant messaging applications. The performance analysis is made by comparing the efficiency and latency time of different encryption methods, showing the pros and cons of using each one.


The model-independent reconstruction of the energy spectra of $\overline{\nu}^{}_e$, $\nu^{}_e$ and $\nu^{}_x$ (i.e., $\nu^{}_\mu$, $\nu^{}_\tau$ and their antiparticles) from the future observation of a galactic core-collapse supernova (SN) is of crucial importance to understand the microscopic physics of SN explosions. To this end, we propose a practically useful method to combine the multi-channel detection of SN neutrinos in a large liquid-scintillator detector (e.g., JUNO), namely, the inverse beta decay $\overline{\nu}^{}_e + p \to e^+ + n$, the elastic neutrino-proton scattering $\nu + p \to \nu + p$ and the elastic neutrino-electron scattering $\nu + e^- \to \nu + e^-$, and reconstruct the energy spectra of $\overline{\nu}^{}_e$, $\nu^{}_e$ and $\nu^{}_x$ by making the best use of the observational data in those three channels. In addition, the neutrino energy spectra from the numerical simulations of the delayed neutrino-driven SN explosions are implemented to demonstrate the robustness of our method. Taking the ordinary matter effects into account, we also show how to extract the initial neutrino energy spectra in the presence of neutrino flavor conversions.


RF electronic circuit is a basically major curriculum of electronic information engineering,which is difficult for teaching and studying. In order to keep up with science development,improve the professional ability of students,and deal with the problems appeared in the teaching process,we put forward some reform measures about teaching improvement practices,such as building up the RF circuit system lab,increasing the practical training of RF circuit and system. It can be seen that these reform measures have significant influence on enhancing student interest in learning,consolidating the theoretical knowledge,and achieving scientific literacy.


This report provides the first record of the exotic sucker fish P. pardalis from the Cauvery river system, Tamilnadu state, India. Information on the assumed presence of this invasive species based on sightings of a hitherto unknown species by local people and fishermen in stretches of Cauvery river have been confirmed by our study. Sailfin sucker fishes are popular among pet traders and aquarists in south east Asian countries and have been regarded as invaders worldwide. Occurrence of P. pardalis in newer habitats due to its potential invasion in the South Indian waters issues threat to native fauna.


Early onset generalized dystonia (DYT1) is an autosomal dominant neurological disorder caused by deletion of a single glutamate residue (torsinA ΔE) in the C-terminal region of the AAA+ (ATPases associated with a variety of cellular activities) protein torsinA. The pathogenic mechanism by which torsinA ΔE mutation leads to dystonia remains unknown. Here we report the identification and characterization of a 628-amino acid novel protein, printor, that interacts with torsinA. Printor co-distributes with torsinA in multiple brain regions and co-localizes with torsinA in the endoplasmic reticulum. Interestingly, printor selectively binds to the ATP-free form but not to the ATP-bound form of torsinA, supporting a role for printor as a cofactor rather than a substrate of torsinA. The interaction of printor with torsinA is completely abolished by the dystonia-associated torsinA ΔE mutation. Our findings suggest that printor is a new component of the DYT1 pathogenic pathway and provide a potential molecular target for therapeutic intervention in dystonia.


SINCE ITS FIRST DESCRIPTION by Cohn et al1 in 1998, minimally invasive coronary artery bypass graft (CABG) surgery with revascularization of the left anterior descending coronary artery (LAD) using the H graft technique has been proposed as an alternative to conventional coronary revascularization for isolated LAD occlusive disease. This approach involves access through a left anterior small thoracotomy (LAST), followed by limited dissection of the left internal mammary artery (LIMA), exposure and stabilization of the LAD, and interposition of a segment of saphenous vein or other suitable conduit between the LIMA and the LAD, without cardiopulmonary bypass. Considerable advantages of this technique include avoidance of a median sternotomy and extracorporeal circulation and dissection of only a short segment of LIMA; in contrast, the standard LAST procedure requires dissection of a longer segment of LIMA for direct anastomosis to the LAD.2 Limiting dissection of the internal mammary artery facilitates the procedure considerably and minimizes traction on the chest wall, reducing postoperative pain. Potential disadvantages of the H graft technique include a greater risk of graft kinking and the potential for a steal phenomenon, with blood flow being diverted away from the coronary system into the systemic circulation by intercostal arteries and other branches of the internal mammary artery.3 The H graft technique introduces a second anastomosis along with the interposition of an additional conduit which, as in the case of the saphenous vein, may adversely affect long-term patency rates. As a result of its location and configuration as a bridge between the LIMA and the LAD, the newly constructed H graft may become susceptible to injury in the presence of mechanical forces that alter the geometry of the thorax, such as in the case of vigorous external cardiac massage or during emergent chest re-entry. A patient in whom avulsion of a saphenous vein H graft from the LIMA occurred as a result of closed chest cardiopulmonary resuscitation (CPB) followed by emergent median sternotomy, which ultimately led to a fatal outcome, is reported.


Treatment with 10−8 m 1,25‐dihydroxyvitamin D3 for 24 h causes transcriptional activation of the human insulin receptor gene in U‐937 human promonocytic cells. The activation seems to potentiate the response to insulin in terms of glucose oxidation. Wortmannin, a phosphatidylinositol 3‐kinase inhibitor, causes a greater inhibition of insulin‐stimulated glucose oxidation in 1,25‐dihydroxyvitamin D3‐treated cells than in untreated cells. This suggests a stimulation of phosphatidylinositol 3‐kinase activity by 1,25‐dihydroxyvitamin D3, which could mediate, at least in part, the potentiation of the insulin response. Copyright © 2002 John Wiley & Sons, Ltd.


During the process of developing musical education in the new century, the multi-functions of children piano music will play a very important role. Therefore, there is great practical point in the research on the functions of children piano music and their full development in musical education system for developing Chinese contemporary musical education system.


Embankment frost heaving is the key problem for building a high-speed railway in seasonally frozen soil regions. Relying on the practices of multiple frost heaving monitoring for high-speed railway embankment in Northeast China and North China,the construction method of the frost heaving monitoring system was studied,and the method has been successfully applied to the frost heaving monitoring work in Harbin-Qiqihar Passenger Dedicated Line,Datong-Xi'an Passenger Dedicated Line and Mudanjiang-Suifenhe Railway. The frost heaving rules and reasons for a high-speed railway embankment were analyzed based on the monitoring results. The results show that the conditions,such as severe cold,low temperature and high speed should be fully considered in the process of construction for the frost heaving monitoring system,the advanced sensors and internet of things technologies also should be used effectively to the subsystem integration. It has some certain regularity of the embankment frost heaving during high-speed railway constructing in the seasonally frozen soil regions. The embankment frost heaving is inevitable but manageable. The quality of roadbed filling is the basic way and the process control of construction quality is the basic guarantee in the anti-frost heaving effort.