Access to an operation in the second regime, using a large aspect ratio range (R/a=6-9) device, is discussed. The large aspect ratio was chosen to reduce required heating power for second regime studies and to permit large aspect ratio confinement experiments under ohmic, NBI, and ECH heating conditions. In addition, it leads to a simplified machine geometry based on reduced stresses from relatively low values of plasma current and magnetic field strength. Design features include an inside null divertor to test divertor physics at high beta and to provide added flexibility to control the plasma boundary. A close-fitting, adjustable conducting shell providing stabilization against external modes allows study of wall-plasma separation effects and permit R/a variation. The size and field of the SRX conceptual design were selected to minimize cost while maintaining sufficient beam-ion confinement for neutral beam current drive and sufficient bulk-ion thermal confinement for meaningful measurements of tokamak energy confinement scaling at high beta.<<ETX>>


Axin forms a complex with glycogen synthase kinase-3β (GSK-3β) and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin, thereby stimulating the degradation of β-catenin. Because GSK-3β also phosphorylates Axin in the complex, the physiological significance of the phosphorylation of Axin was examined. Treatment of COS cells with LiCl, a GSK-3β inhibitor, and okadaic acid, a protein phosphatase inhibitor, decreased and increased, respectively, the cellular protein level of Axin. Pulse-chase analyses showed that the phosphorylated form of Axin was more stable than the unphosphorylated form and that an Axin mutant, in which the possible phosphorylation sites for GSK-3β were mutated, exhibited a shorter half-life than wild type Axin. Dvl-1, which was genetically shown to function upstream of GSK-3β, inhibited the phosphorylation of Axin by GSK-3β in vitro. Furthermore, Wnt-3a-containing conditioned medium down-regulated Axin and accumulated β-catenin in L cells and expression of Dvl-1ΔPDZ, in which the PDZ domain was deleted, suppressed this action of Wnt-3a. These results suggest that the phosphorylation of Axin is important for the regulation of its stability and that Wnt down-regulates Axin through Dvl.


In this paper we derive the Reynolds type lubrication equation with memory eects for lubrication of a rotating shaft. Starting from the nonstationary Stokes equations and using the asymptotic expan- sion we obtain a law that is nonlocal in time and gives a linear connection between velocity and pressure gradient. Our law tends to the classical Reynolds equation when time tends to innit y. We prove a convergence theorem for velocity and pressure in appro- priate functional space.


In the deregulated Norwegian electricity market a zonal transmission pricing system is used to cope with network capacity problems. In this paper we illustrate some of the problems with the zonal pricing system as it is implemented in Norway. Using small network examples we illustrate the difficulties involved in defining the zones, the redistribution effects of the surplus that a zonal pricing system has, as well as the conflicting interests concerning zone boundaries that are present among the various market participants. We also show that a zone allocation mechanism based on nodal prices does not necessarily lead to a zone system with maximal social surplus. Finally, we formulate an optimization model that when solved yields the zone system that maximizes social surplus given a pre-specification of the number of zones to be used.


International technology of enterprises has made outstanding achievements in China,but also there are many difficulties.On the whole,its development pattern is diversified,but most of the enterprises are still in the early stages of the development of international technology.On the trend of its development,the export-oriented internationalization will be the main mode,the technology for overseas market will be an important target,emerging market economics will be the key areas.


The system partitioning problem in a partitionable mesh connected system (PMCS) is addressed. A two dimensional buddy system (2DBS) is proposed as a partitioning scheme for dynamic resource allocation in a PMCS. Allocation and reclamation algorithms and the method for locating buddies are designed. Internal fragmentation of our proposed 2DBS under various probability distributions of job sizes is analyzed. Experimental results on external and total fragmentations are also presented.


A 52-year-old man was admitted to the hospital after complaining of visual disturbance and ocular pain after the explosion of a tire. An examination revealed a 10-mm-sized medial scleral perforation with uveal tissue prolapse and hyphema. Computed tomography (CT) revealed a highly attenuated foreign body 2.0×1.2 cm in size in the intraconal space. Surgery was performed to remove the stone. Primary repair of the scleral perforation and of the partially ruptured medial rectus muscle was also done. We report a case of the successful management of an intraconal stone.


The present investigation studies the effects of application of repetitive micro-second duration high-voltage double-exponential shaped pulses on water samples containing E. Coli. A high-voltage repetitive pulse generator has been developed to apply these pulses. The design of chamber, operational parameters, and their optimization for the process, the wave-shaping circuitry and the switching circuitry is given utmost importance. It is suggested that repetitive pulse application of the order of about 25-kV/cm electric field intensity be employed for the purpose. Pulsed electric field processing is nonthermal energy efficient alternative to thermal pasteurization techniques. It is applicable in many liquid food processing industries like drinking water segment, beer & beverages, fruit juices and milk.


Maximizing the business value while preserving the alignment to strategic objectives is a permanent concern of every organization. Therefore selecting the project portfolios that are more likely to convert a company vision into a business success is a crucial process. The project portfolio selection problem has caught the researcher's interest since more than four decades and has been approached in different methodologies, techniques and decision support systems. However, there is no agreement today on a universal approach addressing this problem's major aspects in a flexible and practical way. This paper is aiming to provide project management practitioners with a fundamental background towards an effective project portfolio selection process. It provides a detailed problem clarification and breakdown from both best practices and literature perspectives. It also synthesizes the various approaches and methods that have been so far proposed in the literature with regards to project portfolio selection. Thus a critical analysis of the most widely used approaches is presented. Furthermore, a concept of an effective project portfolio construction framework is outlined in order to guide future research in that area.


The prevalence of disabling stroke in South Africa is already higher than in high income countries. Exposure to stroke risk factors is already at alarming levels and is likely to increase, adding further to the burden of stroke. The obvious solution from a health care perspective is to reduce risk at a population and high-risk individual level. However, for the individual presenting with an acute stroke the best possible care is needed to optimise their outcome and own personal long-term burden of disease.


【Objective】To observe the clinical efficacy of treating hydatoncus in anterior horn of meniscus by resecting hydatoncus in arthroscope and thread string inside the knee joint. 【Methods】14 patients with 15 cases with hydatoncus in anterior horn of meniscus by resecting hydatoncus in arthroscope and thread string inside the knee joint had been brought into this study, followed up 12 monthes in average and evaluated clinical efficacy based on Barrett standard and follow- up in patients with IKDC and Lysholm score.【Results】14 cases had gotten clinical healing in 15 cases with 93.3% healing rate. Average IKDC score increased to(81.5±3.69) postoperatively from(53.8±4.25) preoperately and average Lysholm score increased to(80.6±6.58) postoperatively from(54.4±6.27) preoperately. 【Conclusion】The technique of treating hydatoncus in anterior horn of meniscus by resecting hydatoncus in arthroscope and thread string inside the knee joint is an effectual and simple way, and it is an innovation of arthroscope technique.


Summary The article proposes one of the approaches to the studying of interjections from the perspective of communicative lingnistics. Interjections are considered as a socially important words isolated in a stream of speech and understood by the communicants. Having no subject and logical value, interjections have communicative meaning associated with the manifestation of emotional and evaluative or emotional and motivating reaction of the communicants in the particular speech situation. Within the situational and psychological context interjections can act as a nominee of the nonsegmented situational nominations having a microsituation as its referent.


The paper presents important criteria for human health estimation in urbanized industrial areas. On the contrary, environmental and economic conditions are successfully identified on the basis of population' elemental status. Cause-effect relations between micro and macro element consumption (lack or abundance) and public health in North-West Federal District of the Russian Federation have been established using the open press sources. Data capturing and visualization are made. Spatial digital maps presenting element consumption for non-personalized groups as well as their main disorders are obtained. The environmental situation in urbanized regions should be used to make future modeling possible for the purposes of a green economy. The paper demonstrates there al picture of availability of macro and micro elements, their lack or abundance. Maximum disease cases per 1000 people appear in the Republic of Karelia, and minimum is in the Leningradskaya Oblast. In practice, mercury abundance is a stimulating agent for most disorders of different origin, which primarily, for example, neoplasms and leukemia. Monitoring and correction of chronic toxic metal exposure at the individual and population levels can significantly reduce expenses on educational and medical services, increase labor efficiency.


Composite circulation is studied for long-lasting and short-lasting El Nio events. The result shows that the low-level wind and high-level velocity potential anomalies are quite different in the occurring, developing and vanishing of the two El Nio events. The result also reveals the key anomalous circulation for the occurring and vanishing of El Nio. Corresponding to the long-lasting El Nio event, cyclonic anomalous circulation over the eastern North Pacific weakens slowly and anticyclonic anomalous circulation over the western North Pacific strengthens slowly at 850 hPa. Therefore the tropical Pacific westerly anomaly keeps long. The anomalous positive velocity potential over the western South Pacific at 200 hPa, which is related to the strong Australian winter monsoon, helps a long duration of El Nio. Corresponding to the short-lasting El Nio, the anomalous positive velocity potential over the western Pacific at 200 hPa moves eastward quickly and results in the vanishing of El Nio event.


These years, the design of multidimensional data model has become a key technology in data warehouse and on-line analytical processing area. Features of air traffic management and decision support system are introduced. Then, an improved four-stage standardized modeling method is proposed. The UML class graph is adopted in the new modeling method, which made it more clear to display the whole logic data structure and more convenient to describe the meta-data model of the data warehouse. As a result, this new four-stage method is suitable to reflect the subject-oriented feature of data warehouse. Under the guidance of this method, the data model for data warehouse of Air Traffic Flow Management System (ATFMS) is presented.


This paper describes an intensive training program in drug education for teachers, presents an evaluation of the program, and discusses the results in terms of the implications for future drug education programs. The major goal of the training program was to positively affect the teacher-student interaction concerning drugs by training the teacher in each aspect of the interaction, facilitating the teacher's awareness of his own drug attitudes and interpersonal style, developing insight into the psycho-social context of student drug usage, and providing accurate information about the pharmacological effects of drugs. Evaluation of the program was made with survey instruments administered on the first and last days of the three-week training course. The instrument consisted of items designed to assess demographic characteristics; training course expectations; attitudes about the educational process, drug usage, and controversial aspects of the current youth scene; drug knowledge; and the evaluation of specific aspects of the course. Although pre-post differences were relatively small and were not statistically significant, drug knowledge showed a substantial increase, and attitudes about drugs and drug users became less negative and more nonjudgmental. Attitudes about the educational process and feelings about youth essentially remained at the same level. An overwhelming majority of teachers felt that the training course had provided valuable results for them and that they would be better teachers as a result. There is little evidence, however, for any major attitude change in the manner they perceived drugs and the drug user from a philosophical and moralistic viewpoint. It is important to reexamine the administrative goals of drug education programs, the process of selectively recruiting drug education staff, and inservice training strategies. An appropriate goal may be the facilitation of an awareness among students of their own motivations for using drugs and the development of a more intelligent decision-making process about drug usage. It appears from the training course data that those teachers with less traditional attitudes about education and/or less negative attitudes about the current youth scene tended also to have a less negative and judgmental attitudes about drugs and drug users and may thus be able to more easily establish good rapport with young people. Finally, the public school administration should treat drug education as a specialized subject area, and implement a selection process to identify those teachers who have the most likelihood of successfully achieving program goals. For this staff, inservice training might focus on the communication process, on the dynamics of value clarification, and on the adoption of effective interpersonal skills, in addition to more factual material.


The utility model discloses a display screen fixing element which is characterized by comprising a baffle plate, a fixing plate and a transition plate, wherein the baffle plate is long-bar-shaped and is used for shielding a display screen; the fixing plate is long-bar-shaped, is parallel to the baffle plate, and is used for being fixedly connected with other structures; the transition plate is used for connecting the baffle plate with the fixing plate; the transition plate is vertical to the baffle plate and the fixing plate which are symmetrically provided with fixing holes; the central part of the fixing plate is provided with a spacing hole; and the baffle plate, the transition plate and the fixing plate are integrally punched and formed. The display screen fixing element provided by the utility model has the beneficial effects that the baffle plate and the fixing plate are long-bar-shaped, and are simple in structure; the number of the fixing holes are multiple, and are distributed symmetrically; the display screen is firmer to fix, and the fixing holes are solid and durable; the central part of the fixing plate is provided with a spacing hole, so that the position of the fixing element is convenient to determine, and the installation efficiency can be improved; and the baffle plate, the transition plate and the fixing plate are integrally punched and formed, and are convenient to manufacture.


Objective To provide anatomical evidence for the bladder operation and the bladder puncture through the anatomical observation and measurement to bladder triangle and its surrounding structures.Methods 31 cases cadauer(male 29,female 2)were measured and analyzed the data concerned bladder triangle and its surrounding structures.Results There is no direct correlation between the size of bladder triangle and the body height.The following distance differences exhibited statistical significance(P0.05): between the cape to under angle and to left angle or right angle of bladder triangle,between the superficial inguinal rings to each angle of bladder triangle,between left or right internal iliac artery to each angle of bladder triangle.Conclusions The data obtained from the bladder triangle of adult cadauer may provide important anatomic evidence for the clinical diagnosis and treatment of these diseases related bladder triangle as well as for the bladder puncture.


The room‐temperature thermal conductivity of III‐V compounds is analyzed. The phenomenological approach of Abeles is applied to take into account disordered structure of ternary and quaternary alloys. The procedure is used for the In1−xGaxAsyP1−y quaternary alloy. The approximate analytical expression for this case is derived. A more exact method of the calculations is also proposed. It enables presenting the thermal conductivity and the thermal diffusivity for both the InP lattice‐matched and GaAs lattice‐matched In1−xGaxAsyP1−y alloys as a function of their composition.


Background:
 Heart failure (HF) portends significant morbidity and mortality. Integrating palliative care (PC) with HF management may improve quality of life, communication, and preparedness planning. At the VA hospital in West Haven, CT, PC was utilized in 6.5% of patients admitted with HF from October 2019 to September 2020. We sought to increase the percentage of referrals to PC from 6.5% to 20% by May 2021.

 Methods:
 PC referral criteria were developed and used to screen all patients admitted to the medical service with HF between October 2020 and May 2021. Patient-centered education on the benefits of PC was delivered initially to medical teams caring for patients who met PC referral criteria and subsequently to all teams. Changes were tested using Plan-Do-Study-Act (PDSA) cycles. Results were analyzed using run charts.

 Results:
 Between November 2020 and May 2021, there were 109 HF admissions in patients who were not already followed by PC. Thirty-one (28%) received a new PC consult. The mean age was 83 ± 9.5 years, median B-type natriuretic peptide was 1202 pg/mL, and mean hospital length of stay was 8 ± 5 days. Kansas City Cardiomyopathy Questionnaire-12 was performed on 15 of the 31 patients with a mean score of 60 ± 22. After our intervention, a shift in the percentage of referrals was demonstrated with 6 consecutive data points above the fixed baseline median (Figure). During the index hospitalization, 5 patients died, 4 of whom had a PC consult.

 Conclusion:
 Through multiple PDSA cycles, referrals to PC for patients admitted with HF increased from 6.5% to 28%. Patient-centered education was an effective tool to teach medical teams about the benefits of PC. Furthermore, inpatient teams more consistently and independently considered PC for patients with HF, representing a cultural shift. This Quality Improvement model may serve as a paradigm to improve the care of HF patients.


The scope of television narrowcasting which provided programmes for a specific target audience is discussed. Several examples are provided to explore the manner in which such programmes expand the limits of meaning by being familiar to regular viewers and interesting to new, uninitiated viewers.


International research indicates that reductions in greenhouse gas emissions are necessary to mitigate climate change. Australia, in particular, has an urgent need to do so, as it's per capita emissions are among the highest in the world. Building owners facing investment decisions are ill-equipped with information as to the technical necessities that upgrade their particular building to achieve deep emission cuts and the financial impact the decisions have on the net present value and internal rate of return investment criteria. Previous studies lack specificity and provide 'only' generic figures for upgrade costs and do not take into account differences in buildings with regard to their attributes and locations. This research investigates methods to provide greater precision for sustainable refurbishments and their optimal timing. An office building in Melbourne was used to develop sets of improvements using an integrated approach to upgrade mechanical services and the building envelope. Using asset management trigger points the impact on net present value and internal rate of return were calculated, taking into account the capital expenditure required, the energy savings due to the refurbishment, as well as a possible rental increase due to the upgrade and lesser operational energy bills for the tenants. To investigate the importance of the location attribute the upgraded building was modelled in a different climate by using a Brisbane weather file. This research clearly indicates the importance of a refined method for sustainable upgrades taking into consideration building attributes and location as well as the lifecycle approach and timing of asset management decisions. The results show the usefulness of the applied method, the various upgrade technologies, the timing of the decision in regards to investment criteria and how they might differ in different climates.


Elevated standardised mortality ratio of cardiovascular diseases (CVD) in patients with brain tumours may result from differences in the distribution of risk factors. We compared the risk of CVD among patients with a primary malignant or non-malignant brain tumour to a matched general population cohort, accounting for other co-morbidities.

 Using data from the Secured Anonymised Information Linkage (SAIL) Databank in Wales (United Kingdom), we identified all adults aged ≥18 years in the primary care database with first diagnosis of malignant and non-malignant brain tumour identified in the cancer registry in 2000-2014, and a matched cohort (case-to-control ratio 1:5) by age, sex and primary care provider from the general population without any tumour diagnosis. Outcomes included fatal and non-fatal major vascular events (stroke, ischaemic heart disease, aortic and peripheral vascular diseases) and venous thromboembolism (VTE). We used multivariable cox models adjusted for clinical risk factors to compare risks, stratified by tumour behaviour and follow-up period.

 There were 2,869 and 3,931 people diagnosed with malignant and non-malignant brain tumours, respectively, between 2000 and 2014 in Wales. They were matched to 33,785 controls. Within the first year of tumour diagnosis, malignant tumour was associated with a higher risk of VTE (hazard ratio [HR] 21.58, 95% confidence interval 16.12-28.88) and stroke (HR 3.32, 2.44-4.53). Risks of VTE (HR 2.20, 1.52-3.18) and stroke (HR 1.45, 1.00-2.10) remained to be higher than controls for those surviving one year. Patients with non-malignant tumours had higher risks of VTE (HR 3.72, 2.73-5.06), stroke (HR 4.06, 3.35-4.93) and aortic and peripheral arterial disease (HR 2.09, 1.26-3.48) within the first year of diagnosis compared with their controls.

 The elevated CVD and VTE risks suggested risk reduction may be a strategy to improve life quality and survival in people with a brain tumour.


A 90 years old woman, in good physical condition, and without history of chronic disease, smoking or alcohol abuse, presented in the Emergency Department of our Hospital, complaining about abdominal pain with a specific location at the right upper quadrant. Her symptoms started approximately a month ago. She was a farmer and a habitant of a Greek rural district. Her blood tests were all within the normal ranges, but her chest x-ray revealed a surprise at the right lower: a big, spherical cystic lesion with a characteristic calcified ring around it, coming out of the right lung. In view of this finding, the patient was admitted and abdominal computer tomography (CT) and ultrasound were performed, which demonstrated the typical imaging features of an hydatid cyst (8.5 x 9.5 cm) ,cited at the right lobe of the liver. Surgical treatment of the cyst was not preferred, because of the age of the patient and the possibility of postoperative complications. In her follow up, she remained in good health and free of symptoms. The differential diagnosis of liver hydatid cyst includes polycystic liver disease, hepatic abscess, hepatocellular carcinoma, hepatic and amebic cysts, but the very specific imaging findings in CT are usually enough to establish the diagnosis. In conclusion, this case underlines the diagnostic value of the chest x-ray which remains the keystone imaging method for any clinical physician. Furthermore, echinococcosis, although considered as a "forgotten" disease, still remains a public health problem for many epidemic areas around the world.


To provide a means to adjust the photographic area of a camera, people without pre-condition to predict changes to create a table, and even in the case of multiple cameras in part a failure occurs, it is possible to completely no dead ends photographic subject area. The camera which is terminated by a plurality of cameras adjusts the image capturing area of the image capturing area of one camera adjustment device, comprising: a camera (201), by shooting in a certain region within a certain time that the position of the image capturing area change obtained virtual Photography region; adjusting unit a (202), adjust the virtual photography location of the region; a communication unit (203), a transceiver represents a virtual photographic area of a virtual image capturing area information; adjustment unit a (202) according to the virtual image capturing area of the camera terminal and virtual image capturing area of the other cameras dummy photographic area information by the communication unit (203) receives the representation to adjust the position of the virtual image capturing area of a camera, so that the plurality of cameras and photographic virtual area specified region completely covered photographic subject region.


Personalized data access has become one of the core challenges for intelligent information access, especially for nonmainstream long-tail content, as can be found in digital libraries. One of the main reasons that personalization remains a difficult task is the lack of standardized test corpora. In this paper we provide a comprehensive analysis of feature requirements for personalization together with a data collection tool for generating user models and collecting data for personalization of search and recommender system optimization in the long-tail. Based on the feature analysis, we provide a feature-rich publicly available data set, covering web content consumption and creation tasks. Our data set contains user models for eight users, including performed tasks, relevant topics for each task, relevance ratings, and relations between focus text and search queries. Altogether, the data set consists of 217 tasks, 4562 queries and over 15.000 ratings. On this data we perform automatic query prediction from web page content, achieving an accuracy of 89% using term identity, capitalization and part-of-speech tags as features. The results of the feature analysis can serve as guideline for feature collection for long-tail content personalization, and the provided data set as a gold standard for learning and evaluation of user models as well as for optimizing recommender or search engines for long-tail domains.


Objectives: The purpose of this study was to investigate whether swimming regulates menopause-induced obesity through the regulation of genes involved in lipid metabolism(: lipolysis, lipogensis and adipogenesis) in female ovariectomized mice, an animal model of postmenopausal women. Methods: For all experiments, eight-week-old female mice(C57BL/6J) were ovariectomized(OVX) and each randomly divided into two groups (a non-swim control group and a swim group, n=8/group). Mice in swim group swam for 2 h daily for 6 weeks in a 35±1℃ water bath. All the animals received a high fat diet(45% kcal fat) for 6 weeks. To elucidate the mechanism, reverse transcription-polymerase chain reaction were performed using white adipose tissue. Results: Swim-trained mice had significantly decreased body weight, adipose tissue weights and serum glucose levels compared with sedentary control mice. Concomitantly, swimming significantly increased mRNA levels of peroxisome proliferator-activated receptor α(PPARα) target genes responsible for fatty acid β-oxidation, such as carnitine palmitoyltransgerase-1 and thiolase in the white adipose tissue. However, mice exercised by 6-weeks swimming had decreased the mRNA expression of lipogenic genes, such as sterol regulatory element- binding protein-1C(SREBP-1C) and fatty acid synthase compared with sedentary control mice, with decreases PPARγ target genes involved in adipogenesis, such as adipocyte fatty acid binding protein and leptin. Conclusion: These results suggest that swimming can effectively prevent obesity caused by ovariectomy, in part through activation of PPARα and PPARγ as well as SREBP-1C in white adipose tissue of female obese OVX mice. Moreover, these results suggest that swimming maybe contribute to the alleviation of metabolic syndrome, including obesity and hyperlipidemia, in postmenopausal women, in part through the regulation of genes involved in lipid metabolism. [Supported by grant No. KRF-2009-351-G00135 from Korea Research Foundation]


Dear Editor, Chromoblastomycosis (CBM) is a chronic fungal infection that affects the subcutaneous and cutaneous tissues. A 71-yearold male agricultural worker, born in and resident of Natal, Brazil, reported that he used to work for 20 years in an endemic region of CBM in Brazil (Para State, North Region), where he developed a lower limb injury. The lesion observed on the right lower limb was classified as an erythematous desquamative plaque, on 3 March 2011 (Fig. 1a). In April 2011, a histopathological examination was performed where hyperkeratosis, pseudoepitheliomatous hyperplasia, chronic inflammatory infiltrate and microabscess in addition to sclerotic bodies were found. The patient started medical treatment in the same month, consisting of oral itraconazole 100 mg twice daily and a complementary therapy with cryotherapy once a month for 10 months. After this period, the cryotherapy sessions were performed every 2 months where hyperkeratosis and ulcerations with spontaneous healing were still observed (Fig. 1b). After 13 months of treatment with itraconazole, the lesions still exhibited dark dots. In April 2012, the patient was submitted to laboratorial investigation (Fig. 1c). The collected epidermal scales were treated with 20% KOH and subsequently visualized by direct microscopy. The scales were seeded onto seven equidistant points on the surface of Sabouraud's dextrose agar with added chloramphenicol, and the Petri dish was incubated at room temperature (28 2°C) for 30 days. A small amount of mycelia was then subcultured on a microculture of potato dextrose agar (PDA). The Petri dish was incubated at room temperature for 10 days. The presence of muriform (sclerotic) cells with a dark, thick membrane showing internal septation in addition to dematiaceous septated hyphae were observed on direct examination (Fig. 1e). After 10 days of incubation on PDA, the colony presented a velvety to cottony texture with olive to brown-black color and no reverse pigment (Fig. 1f). The micromorphological structures were observed on optical microscopy (Fig. 1g,h). The etiological agent was identified as Fonsecaea spp. and further sent for molecular identification at the Special Mycology Laboratory, from the Division of Infectious Diseases, Federal University of Sao Paulo. The isolate was finally identified as Fonsecaea pedrosoi with 99% identity. The sequence was deposited in the GenBank database under accession no. KC357715. In April 2012, after 13 months of treatment with oral itraconazole, the patient was submitted to a change of drug therapy (a) (b)


The hazards of forest fire were analyzed.Directive and decision system of forest fire prevention was briefly introduced.The decision-making system functions of forest fire prevention were elaborated in detail from electronic map management,information query,popular information,fire statistical statements,decision support,fire loss calculation,three-dimensional electronic sand table,GPS real-time monitoring and so on.


This paper invesigates the peak ground acceleration (PGA) and peak ground velocity (PGV) regression equations as well as the PGA or PGV middle values in Chinese seismic intensity scale 2008 (the CSIS 2008), using the Wenchuan earthquake records of China with the full seismic information. Based on the analytical results, the PGA-V method is proposed to assess the instrumental intensity which combines both PGA and PGV. Besides, a problem is raised to further verify and modify the middle values of PGA or PGV for the seismic intensity VI and VII in the CSIS 2008.


The now seed dressing fungicides Panoctine and Panoram were compared with other commonly used fungicides for their effect on sorghum seed viability during storage. Thiram 0.2 per cent, Vitavax 0.2 per cent, Panoram 0.4 per cent and Panoctine 0.4 per cent were found to keep the sorghum seeds viable to nine months of storage.


The present invention discloses an antibacterial porcine small intestinal degradation of extracellular matrix preparation off, comprising the following steps: 1) using genipin crosslinked porcine small intestinal acellular matrix, then rinsed and dried; 2) step 1) to give the porcine small intestine by genipin crosslinked acellular matrix placed dopamine solution soak, then rinsed and dried; 3) after the step 2) treated porcine small intestinal acellular matrix placed in the silver nitrate solution soak, then rinsed and dried . The present invention also discloses the use of antibacterial resistance to degradation of the porcine small intestinal acellular matrix in high stress areas of tissue repair. The present invention also acellular porcine small intestinal matrix was modified and antimicrobial resistance to degradation, and proved its antibacterial properties and resistance to degradation are relative small intestinal native porcine acellular matrix is significantly enhanced, remained good biocompatible resistance, repair tissue can be applied in high stress areas.


The G‐Wishart distribution is the conjugate prior for precision matrices that encode the conditional independence of a Gaussian graphical model. Although the distribution has received considerable attention, posterior inference has proven computationally challenging, in part owing to the lack of a direct sampler. In this note, we rectify this situation. The existence of a direct sampler offers a host of new possibilities for the use of G‐Wishart variates. We discuss one such development by outlining a new transdimensional model search algorithm—which we term double reversible jump—that leverages this sampler to avoid normalizing constant calculation when comparing graphical models. We conclude with two short studies meant to investigate our algorithm's validity. Copyright © 2013 John Wiley & Sons Ltd


ion from the solvent or from the substrate. It is important to mention that other mechanistic possibilities may take place. Thus coordination of radicals to Ni(I) instead to Ni(II) Scheme 2. Scope of the cyclization/cross-coupling reaction for alkyl-ZnBr (a) and aryl-ZnBr (b) reagents. [a] Yield was determined by H-NMR using hexamethyldisilane as internal standard. Scheme 3. Retrosynthetic analysis. Research Article doi.org/10.1002/ejoc.202200992 Eur. J. Org. Chem. 2022, e202200992 (3 of 5) © 2022 The Authors. European Journal of Organic Chemistry published by Wiley-VCH GmbH Wiley VCH Montag, 21.11.2022 2244 / 275877 [S. 33/35] 1 100690, 222, 4, D ow nladed from htt://chem istry-euronlinelibrary.w il.com /doi/10.1ejoc.202200992 by U nivrsidad A unom a D e M arid, W ley O nline L irary on [28//2022]. ee he T rm s nd C onitions (https:linelibrary.w il.com /erm s-andnditions) on W ley O nline L irary or rles of use; O A aricles re goerned by he apicable C retive C om m ns L icnse species has been proposed in some cases, and we cannot discard this alternative.


As previously reported [Ishii, K., Iwasaki, M., Inoue, S., Kenny, P. T. M., Komura, H. & Inoue, Y. (1989) J. Biol. Chem. 264, 1623-1630; Inoue, S., Iwasaki, M., Ishii, K., Kitajima, K. & Inoue, Y. (1989) J. Biol. Chem. 264, 18520-185261, the unfertilized eggs of two different species of fresh-water fish, Plecoglossus altivelis and Tribodolon hakonensis, contain relatively large amounts of free sialooligosaccharides. These oligosaccharides were found to derive from glycophosphoproteins, owing to the activity of a peptide - N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase [Iwasaki, M., Seko, A., Kitajima, K., Inoue, Y. & Inoue, S. (1992) J. Biol. Chem. 267, 24287-24296; Seko, A., Kitajima, K., Inoue, Y. & Inoue, S. (1991) J. Biol. Chem. 266, 22110-22114]. Here we describe a new type of free oligosaccharides, isolated from unfertilized eggs of Scyliorhinus caniculus. From the structural analysis, based upon 1H-NMR spectroscopy, the following glycan units are proposed.[Formula: see text]


The research and application of predictive functional control is mainly focused on single-variable system. The actual object is multivariable systems. So it is necessary to research a predictive functional control for multivariable systems. This paper mainly studied the basis function, reference trajectory, and the output of the predictive model. Finally, The expressions of control of the multivariable predictive function control algorithm can be deduced in this paper. The state space equations are adopted by the controlled object, and then the multivariable system is simulated by MATLAB. The simulation results show that the control algorithm of MPFC can achieve better control effect and quickly make the system get a stable state, but some overshoot is appeared.


The spectrally and temporally resolved UO2+2 fluorescence signals have been measured for solid samples of UO2+2-Datura, UO2+2-(immobilized Datura), and UO2+2-(silicate polymer) at liquid nitrogen temperature. The binding capacity of UO2+2 to Datura innoxia cell material has been enhanced significantly at pH 5 and 6 when immobilized in a polysilicate matrix. New binding sites having a greater binding strength with a lower availability have been observed for the binding of UO2+2 after immobilization of the cultured biomaterial. However, chemical alteration of the cell material resulting from this immobilization process has not been observed. The chemical environment of the binding sites responsible for the binding of UO2+2 in immobilized and free D. innoxia cell material has been demonstrated to be different. This difference results from the immobilization of the cell material within a polysilicate matrix.


Important layout properties of electronic designs include space requirements and interconnection length values. A reliable interconnection length estimation is essential for improving placement and routing techniques. Accurate estimates can also be used to compare architecture features before these architectures actually have to be built. Donath found an upper bound for the average interconnection length for a two-dimensional placement that follows the trends of experimentally obtained average lengths [Don79]. Yet, this upper bound deviates from the experimentally obtained value by a factor of approximately 2 which is not su ciently accurate for some applications. In this report we search for the main reasons for the deviation. We will propose some improvements and evaluate them with respect to the limitations imposed by Rent's rule [LR71]. We show that we can obtain a signi cantly more accurate estimate by taking into account the inherent features of the optimal placement process. In this report, improvements on Donath's technique will be presented both for twoand three-dimensional placement. Therefore, the extension of Donath's technique to three dimensions will also be presented.


Case 5, Dr. Grace Griffith.-A case of Erythema Iris in a male aged 23 years. The patient gave a history of irritation on the backs of his elbows four days before the rash appeared. At first there were a few spots, and each day he noticed a few more all coming in the same region close to each other. He had had eight attacks in the last three years. The first attack was the worst, and lasted five weeks. All the attacks occurred over the same region. The rash never spread further or attacked other parts of the body, and each attack lasted from two to five weeks. The spots itched and burned at night. He was in good general health, and gave no history of having had any debilitating illness. He had had recent attacks of pain in his shoulders, which he called muscular rheumatism. He had not had a sore throat recently, and his tongue was not sore. On examination the patient had symmetrical lesions on the extensor surfaces of his arms: most marked about the elbows. The lesions were discreet, circular patches, with pale raised urticarial margins, each surrounding a central macule or papule, or, in older lesions, a dull purplish spot. Examination of his mouth showed no typical lesions on his mucous membrane, but the soft palate and fauces were studded with clear papules, giving them a granular appearance. He had a couple of carious teeth which had ached recently. No other abnormality was found.


Gas Hydrates Markup Language (GHML) has been under development since 2003 by the CODATA Task Group "Data for Natural Gas Hydrates" as an international standard for data storage and transfer in the gas hydrates community. We describe the development of this evolving communication protocol and show examples of its implementation. In describing this protocol, we concentrate on the most recent updates that have enabled us to include ThermoML, the widely used IUPAC XML communication standard for thermodynamic data, into the GHML schema for the representation of all gas hydrate thermodynamic data. In addition, a new GHML element for the description of crystal structures is described. We then demonstrate a new tool Guided Data Capture for Gas Hydrates for the rapid capture of large amounts of data into GHML format. This tool is freely available and publicly licensed for use by any gas hydrate data producer or collector interested in using the GHML format. An effort will be made to achieve a consensus between scientific journals publishing thermophysical and structural data for gas hydrates to recommend their authors use this new software tool in order to generate GHML data files at the time of the submission of scientific articles. Finally, we will demonstrate how this format can be used to advantage when accessing data from a web-based resource by showing on-line access to GHML files for gas hydrates through a web service.


Even the history of philosophy is completely without interest if it does not undertake to awaken a dormant concept and to play it again on a new stage, even if this comes at the price of turning it against itself.1 History of Philosophy: Recounting Imaginary Books Gilles Deleuze observes a distinction between writing history of philosophy and "doing" philosophy. We are interested here in how this distinction is set up. How does Deleuze conceive of the relation between history of philosophy and doing philosophy? What is the use of historiography and how can it be brought to bear on the present? In the preface to the English edition of Difference and Repetition Deleuze writes this: There is a great difference between writing history of philosophy and writing philosophy. In the one case we study the arrows or the tools of a great thinker, the trophies and the prey, the continents discovered. In the other case we trim our own arrows, or gather those which seem to us the finest in order to try and send them in other directions, even if the distance covered is not astronomical but relatively small. We try to speak in our own name only to learn that a proper name designates no more than the outcome of a body of work-in other words the concepts discovered, on condition that we were able to express and imbue them with life using all the possibilities of language.2 This metaphor of the arrow is instructive. Deleuze says that "After I had studied Hume, Spinoza, Nietzsche, and Proust, all of whom fired me with enthusiasm, Difference and Repetition was the first book in which I tried to `do philosophy."' Deleuze distinguishes here between his earlier texts on the history of philosophy and his first text which does philosophy-on the one hand, the selection of some arrows and tools, the tensioning of a bow, and, on the other, their deployment in a new direction. Following Nietzsche, Deleuze wants to be an untimely philosopher-he desires a philosophy that is not a philosophy of history, nor a philosophy of the universal, but untimely. That is to say-and these words are Nietzsche's"acting counter to our time and thereby acting on our time and, let us hope, for the benefit of a time to come." Deleuze anticipates a time when it will no longer be possible to write philosophy books as they have been traditionally produced. The search for new means of philosophical expression was begun by Nietzsche, and Deleuze hints here that his own work on cinema, theatre, and the visual arts is animated by this need for new modes of philosophical expression. At any rate it is in this context that Deleuze raises the question of the history of philosophy. He says that the history of philosophy should play a role roughly analogous to collage in painting. This means that elements, or more precisely concepts, are lifted from the textual context in which they were created and juxtaposed with concepts from other places in ways that make familiar concepts strange and imbue them with new powers. A commentary reproduces a concept but it is reproduced in a new context-or rather, on a different plane-and for Deleuze commentary must be conscious of the mutations that occur when historical concepts are reproduced in the present. In fact it is the field of possible mutations which constitute commentary's possibilities. The history of philosophy is the reproduction of philosophy itself. In the history of philosophy a commentary should act as a veritable double and bear the maximum modification appropriate to a double.3 Even more provocatively, Deleuze suggests that it should be possible to recount a real book of past philosophy as if it were an imaginary and feigned book. And here, by way of explanation, he mentions a story by Borges. The story is "Pierre Menard, Author of the Quixote."4 As a guide to what Deleuze might mean here it is quite illuminating. Borges had an extraordinary talent for the invention of imaginary texts. …


Developing optical networks with low latency and high bandwidth is necessary for the next generation of high-speed cellular technologies. It is anticipated that coherent wavelength division multiplexing passive optical networks, also known as WDM-PONs, will play a significant part in these applications. We demonstrate a coherent optical system transmission 1 Tbit/s/λ with high performance using high order modulation (128-256-QAM) data transmission over 200 km single mode fiber-optic will be utilized either in mobile front haul (MFH) or mobile back haul (MBH) in the process of constructing the transport infrastructure of 5G and beyond cellular networks. In this paper, a general structure for 5G cellular network is proposed According to the findings, the strategy that was suggested provides a potentially valuable solution for the development of future 5G transportation systems.


Language, with its plural contents, takes place in the expression of a specific speech, crossed by interdiscursivity, patented in the multiplicity of texts, as Charaudeau and Maingueneau (2011) taught. Every language, being immanent to people with different histories and cultures, has an extensive discursive diversity, reflected in the different domains or communities that take hold of it. All these various domains, however, provide patterns for their speakers to understand each other. These patterns, when grouped in sets, can be considered as grammars that describe the variants of a language, which causes a polysemy inherent to the concepts of "grammar" and "pattern". It is up to the school, in a dialectical perspective involving variants born in several factors, present to the student the standard variant, because this variant is suitable to certain situational contexts and, therefore, their knowledge allows full access to citizenship, as shown by Azeredo (2008). I try in this paper to explain this statement, as well as outline ways to generate a successful standard-grammar teaching, based on a set of practices involving prescription (evidenced by scholars as BECHARA, 1990), subjectivity (taken by linguists as BENVENISTE, 1998) and otherness (presented in the works of FIORIN, 2006; NEVES, 2000 and ANTUNES, 2003).


ABSTRACT We consider the relativistic multi-mode pseudo-Jahn-Teller effect (2Eu + 2A2u) × (big + b2g + eu) for square-planar molecular complexes with a heavy central atom and the odd number of electrons. All 32 elements of the double spin group D4h are determined in the form of space-matrix operators. The 6 × 6 vibronic matrix is derived in the quadratic (with respect to the normal coordinates) approximation for the contributions of electrostatic (non-relativistic) Hamiltonian and in linear approximation for contribution of spin-orbital coupling. Vibronic matrix is represented on the basis of double-value irreducible representations of the symmetry group D4h


ABSTRACT Major Depressive Disorder (MDD) is poorly understood and frequently diagnosed in mental health practice. Qualitative thematic analysis from interviews with 20 licensed clinical social workers (LCSWs) was conducted to evaluate clinicians' perceptions, sources of information, and use of the chemical imbalance theory (CIT) during interactions with clients. Findings revealed that clinicians held nuanced and often critical perceptions of the CIT. When clinicians did incorporate CIT, they did so in highly specific and nuanced ways, often to justify antidepressant treatment. Social workers highlighted a gap in psychopharmacology education and training. Implications for social work education and practice are addressed.


4 x saliva samples (2ml each) from a single adult male volunteer were taken using the GeneFixTM saliva collection device and shipped to the laboratory using the standard Royal Mail postal service. Details of the GeneFixTM saliva collection devices are available separately from www.isohelix.com but the process involves quickly collecting a 2ml saliva sample into 2ml of preservation buffer which fully stabilises the sample for over 12 months at room temperature.


US Wireless (USW, a major wireless location systems supplier, says that mobile telephones could be adapted to do the job of an electronic toll transponder. USW is developing a network of antennas and processors to cover traffic throughout the 100 top metropolitan areas in the country to provide continuous location information on cellular telephones in use. The Federal Communications Commission has mandated that by October 1, 2001, all wireless carriers be equipped to locate people making an emergency or 911 call from their cell phones.


An evaluation of fractal dimensions of both physical particle roughness and grain size distribution of agglomerated boron was determined.The relationship between the roughness and size distribution of boron agglomerate particles and the fractal dimension as well as rheological property of fuel-rich propellant were analyzed.The results show that the rougher the boron particles,the higher the corresponding fractal dimensions,and the higher the fragmentation fractal dimensions,the higher the relative percentage of fine boron particles in the size distribution.The fractal theory is applicable to quantify the irregularity of agglomerated boron particles surface and grain size distribution.


The paper probes how to determine hydraulic system of KZC-5 underground self-discharge tramcar, discusses selecting principle and method for steering and hydraulic system, which prove reasonable by industrial test.


To Rachel II III ACKNOWLEDGMENTS Thanks to my advisor Antony Hosking, who was responsible for getting me interested in persistent systems and who has been a cheerful guide and teacher throughout my time at Purdue. Thanks to my committee members Jens PaIsberg and Aditya Mathur. Thanks to Nate Nystrom for providing invaluable assistance in understanding BLOAT. Thanks to all the members of the lab: Gustavo, Mike, Aria, Anshul and Raghu. Thanks to the Plama group at Glasgow and Sunlabs. Thanks to my wife Rachel for her loving support and thanks [0 my parents and Giri, who gave me support from afar. Thanks to Lyle, Judy, Eli and Dani for everything they have done for me.


In this paper, the non-electro-plating process of carbon nanotube and the powder-metallurgy production of nanotube reinforced Cu-matrix composite is studied. The wear process of the composite was composed of running-in and steady state wear. Finally, research on effect of main factors to the wear of the composite was done. Compared with generic carbon composite, carbon nanotubes are better in wear property.


The thesis examines the social networks of the nobility during the Middle Ages. The networks explain why two noble families, one in Kind and the other in Mark, managed to hold the office of haradshovding (district judge) through several generations and clients, despite the absence of hereditary offices in medieval Sweden. The thesis investigates the creation of the Swedish nobility and its development. It does this by applying a theory called social closure. My thesis shows that the group tried to close its ranks to newcomers who aspired to become members. It therefore became increasingly more difficult to become a noble. Social closure worked within the group as well, stratifying it and creating differences within the nobility. These developments made the social networks of the utmost importance. To become a noble, or to aspire to a higher status within the nobility, an individual had to have powerful patrons. The concept of nobility changed through this process. It went from being tied to service to becoming hereditary, lineage became important. The social networks of the nobility consisted of marriages and kinship, patron-client relationships, and friendships. The relationships were multifaceted and overlapping. It was through these relationships the power base of the two families were created, maintained, and passed on to their heirs. The powerbase consisted of their estates, offices and fiefs, as well as the social relationships. They married their male heirs to daughters belonging to higher noble families. Noble families used their daughters' marriages to tie local lower nobles to them, thus creating important bonds with the local community while also securing clients. The patron-client relationships thus worked together with marriages to form social networks. Noble families also used patron-client relationships to dominate the local community, primarily through the ting (the local court). The benefits to the clients were protection, and affiliation with the local elite, but also access to the offices and therefore the income of the offices. Finally, horizontal and hierarchical friendship also complemented the social networks. The networks help explain why the official power associated with the office became a private power tied to the noble families.


The paper shows, in tabular form, details of all 118 operating longwall faces in the US at June 1985, giving details of face dimensions, winning machines, supports, conveyors and haulage systems and capacity in tons/shift. An accompanying text highlights the principal features.


The inspiration for this study originated from the absence of reference in the theme and the troubling questions that echoed in the chords of the author's lyric self: Is poetry important for nursing referred to as science and art? Considering the full time care, is there place for the aesthetic knowledge, in spite of the same being so little searched? The objective was to reflect and analyze the importance of the poetic text for the aesthetic of nursing knowledge, using as analysis tool the poem On the poetic clay, my reflections on the science care written by the author-nurse, based on the Theory of Complexity. The poem analyzed addresses various dimensions of human complexity necessary for the care of themselves, of others and of the populations who revitalize the inexhaustible aesthetic source and generating health. Poetic elements are fundamental for reflection, production and disclosure of knowledge of nursing aesthetic being essential and inseparable em every action of taking care.


In the paper the outline of the modular, reconfigurable logic controller design is presented. As the initial specification, sequential function chart (SFC-1131) is considered, as well as its equivalent textual specification in structured text. The focused items of design are: modification of the initial specification of the controller by means of introducing separate control part, described as SFC without complex conditions of transitions and only with combinational qualifiers and outputs, and a data path on register transfer level. In the proposed design methodology, after "lifting" such kind of sound SFC is treated as a particular kind of modular control interpreted Petri net. It is first formally analysed, and later described and simulated in HDL environment. Such verified and tested behavioural specification is mapped directly into FPGA matrix structure of reconfigurable logic controller by using standard or dedicated synthesis tools. The dedicated data path is treated as a complex functional building block, which is combined from previously designed modules - IP cores


3D visualization of road geo-information is always the popular disquisitive topic.The paper constructed 3D virtual road sights based on internet with VRML.The author expatiated on the flow and its key techniques in detail.Further more,the author designed an issuance system about 3D virtual road sights based on the C/S pattern.


The invention discloses a backlight module group comprising a reflector, a light source, a three-dimensional optical regulation and control structure, and a supporting structure. The light source is configured on the reflector. The three-dimensional optical regulation and control structure is configured on the reflector, and is used to cover the light source. The supporting structure is configured on the reflector, and comprises a column body, which passes through two parts of the three-dimensional optical regulation and control structure for the supporting of the three-dimensional optical regulation and control structure. By adopting the backlight module group provided by the invention, the costs can be reduced, the three-dimensional optical regulation and control structure can be reduced effectively, and the probability of deformation caused by the vibration, the falling, or the high temperature and high humidity environment can be reduced.


Quality refers to the closeness of an actual outcome to the expected outcome by the observer. In view of the changing scenario of customer needs, lifestyles and technological innovations, the market has become much more quality-conscious. Therefore, in service delivery, quality has become an essential prerequisite even in the healthcare sector. The SERVQUAL model pioneered by Parasuraman et al. (1988) measures service quality and identifies the potential gaps within the service organizations. The present study measures service quality in select hospitals of Krishna District of Andhra Pradesh, and attempts to diagnose service quality gaps. The results of the study confirmed that the demographic factors and socioeconomic status play a vital role in patients' satisfaction towards service quality.


We present a comparison of two conceptual layouts of 100 J class laser systems for HiLASE and ELI Beamlines projects with respect to the output energy, beam propagation and system performance obtained from MIRO code. Both systems are based on cryogenically cooled Yb:YAG multi-slabs amplifiers technology and operate at 10 Hz repetition rate with average power above 1 kW. First concept of the laser system consists of separate 10 J preamplifier and 100 J power amplifiers, while the second consists of a main amplifier with two identical amplifier heads delivering 100 J.


Because of environmental concerns about nitrate and NOx emissions, the present study proposes a novel configuration in order to enhance thermal decomposition of ammonium nitrate (AN) in an environmentally friendly manner. Conventional thermal decomposition of AN takes place in a fluidized-bed reactor (FR) at high temperature, causing high AN conversions as well as considerable amount of NOx formation. The novel configuration considered in this work consists of two cascading fixed-bed and fluidized-bed dual reactors (CFFDRs). Thermal decomposition of AN occurs in the first reactor or the fluidized bed one and NOx is produced as a result. The following fixed bed reactor is a place for the selective catalytic reduction of NO with NH3. Operating conditions for the proposed CFFDR are optimized to achieve a minimum amount of AN as well as NOx via differential evolution (DE) method. Results illustrate that the AN conversion in this novel configuration reaches 98%, which is 42% in the conventional FR. Furthermore...


Electron linear accelerator as a X ray radiation producer can be used in various fields, for example, non destructive inspection in industry, ICT, inspection of container and irradiation processing of cable. The distributing control system (DCS) is brought in accelerator control system. The master device is programmable logical control.


Chemical doping of MXenes with heteroatoms is expected to be a promising strategy to enhance the electrochemical performance. Nevertheless, the synergistic effect of chemical doping and 3D structure construction has...


In this paper, we propose computational algorithms for a pseudo-formal linearization method for nonlinear dynamic systems and a nonlinear observer for nonlinear scalar measurement systems using Chebyshev interpolation. This pseudo-formal linearization method transforms a nonlinear autonomous dynamic system into an augmented linear one with respect to a linearization function that consists of polynomials of state variables. When linearizing, Chebyshev interpolation is exploited so that a computational algorithm is implemented. As an application of this method, a computational algorithm for a nonlinear observer is proposed. Numerical experiments indicate that the performance of the proposed method is superior to that of the previous method.


The present invention relates to a polarizing plate, it relates to a polarizing plate provided with a hard coating film and more particularly showing a high hardness and excellent characteristics. According to the polarizing plate of the present invention, excellent high hardness, scratch resistance, high transparency, shows durability, light resistance, light transmittance and the like, it can be usefully employed in a variety of fields. .BACKGROUND


In recent years, the quality and safety accidents of agricultural products have emerged in an endless stream, which has had many negative implications for the quality of life of people and the stability and harmony of our society as a whole. We can propose countermeasures from different perspectives to solve these problems, and among which, it is a proven method from the perspective of the supply chain, which is also a hot academic research at present. This article illustrates the supply chain of the agricultural products and relevant concepts, on the basis of which analyzes the present situation of quality and safety in the supply chain of agricultural products, at last concludes a management model of quality and safety of supply chain of agricultural products from the perspective of government regulation.


The telescopes of the Pierre Auger Fluorescence detector will use a segmented mirror. To align the segments we have developed four methods, which use: a) the image of the stop border, b) the image of a screen with concentric circles and c) the Ronchi pattern. Adding to these, we have developed a new method d). Instead of the Ronchi ruling, we have used a circular grid. In this case we obtain a moire pattern for each segment by means of which the experimental setup is simplified and the sensitivity of the alignment is improved.


Abstract BACKGROUND Whilst rates of survival following paediatric brain tumour have increased, quality of survival continues to present a significant challenge to children and their families. The neurocognitive impact of cranial radiotherapy (CRT) in childhood upon future intellectual development is well established. Both CRT and chemotherapy are associated with medium-term slowed speed of cognitive processing, attention, and memory impairment, and with longer-term failure to achieve pre-morbid intellectual potential and low Health-Related Quality of Life (HRQoL).Methylphenidate is a psychostimulant drug shown to be effective in alleviating some of the neurocognitive symptoms of cancer treatment, however the subjective experience of paediatric participants is not reported. AIM: The current study aimed to explore the subjective experience of HRQoL in paediatric neuro-oncology patients currently receiving methylphenidate. METHODS A retrospective audit was conducted on 12 paediatric neuro-oncology patients in receipt of methylphenidate. Both standardised and novel measures were used to assess aspects of HRQoL, specifically; social life, perceived independence, mood, confidence, school life, self-esteem, interpersonal relationships and fatigue levels. Data collected were analysed using Thematic Analysis. RESULTS Five key themes were identified; physical, emotional, social, academic and neuropsychological impact. CONCLUSION The current findings evidence the perception of patients that methylphenidate supported them to regain previously lost functionality. Methylphenidate has the potential to increase HRQoL in this population and to provide children with the opportunity to regain a sense of normality in their lives.


: The superior mechanical behavior of Shape Memory Alloys (SMAs) has attracted the researchers from different fields. Less interest was noticed in the structural engineering field due to the high cost of these materials especially for large-scale applications. The SMAs are mainly characterized by the super-elasticity and shape memory effect phenomenon that reflects the ability of the SMAs to recover their original shape after being deformed beyond the elastic limits upon stress removal by heating through thermal heat transformation from martensite to austenite and can provide an active external strengthening mechanism to Reinforced Concrete (RC) members. Recently, an Iron-based SMA (Fe-SMA) reinforcement has been developed. The Fe-SMA is relatively inexpensive compared to the conventional Nickel Titanium (NiTi) alloys due to the lower cost of the constitutive materials and availability of mass production facilities of structural steel. As project studying potential of in strengthening RC beams for flexure, this paper reports on the static flexural behavior and ductility of RC beams strengthened with prestressed near-Surface Mounted (NSM) Fe-SMA bars in the form of bars embedded inside a groove pre-cut into the concrete cover on the tension side of beam and filled with epoxy adhesive . The pre-strained Fe-SMA bar was mounted in a groove cut near the concrete surface on the tension side of the beam. The Fe-SMA bar was then heated up to 350 o C which resulted in a stress recovery in the bar that counteracts the applied loads to the beam, and eventually increases its flexural capacity. The results showed that the yielding and ultimate loads of the strengthened beam were considerably improved. More importantly, the ductility was also significantly improved. The test results were compared to another experimental results found in literature for RC beam with the same properties but strengthened with Carbon Fibre Reinforced Polymer (CFRP) NSM strip having the same prestressing force. Although the NSM CFRP strip resulted in higher ultimate flexural capacity, but the ductility was compromised unlike the beam strengthened with NSM Fe-SMA bar.


Postcoital bleeding (PCB) is defined as any bleeding or spotting unrelated to menstruation that occurs during or after sexual intercourse. It is a relatively common complaint presenting to general practice, and can sometimes prove challenging to diagnose and manage, due to the number of conditions that can cause PCB. It can cause a lot of distress to the patients, as many will associate such bleeding to a malignant cause. At the same time, some patients will take it lightly and present late. There are no current national guidelines in the UK for PCB, which may contribute to inconsistencies in investigation and management. There are many common and uncommon causes of PCB. This article will explore these with the help of a clinical scenario. An aid to diagnosis and management will be discussed.


In the process of particle settling in a dilute,a density graded distribution of the liquid below the suspension needs to be designed according to the gravity of the suspension prior to sedimentation.In the present paper a compositionally graded W-Mo composite was formed via the settling of the W and Mo particles,with a density gradient distributed in the initial clear liquid along the settling direction.


This paper presents a model to demonstrate that, when di¤erences-of-opinion over individual securities have a common component, the valuation of the aggregate market can be higher than its fundamental, even if all investors agree on the market fundamental. Using analyst forecast dispersion to measure disagreement, I …nd empirical evidence that individual stock disagreements co-move and the common component mean-reverts, the common disagreement has substantial explanatory power for the time-series variation of equity premium, and the common disagreement correlates with discount-rate news rather than cash-‡ow news and has explanatory power for the time-series variation of value premium. I thank Douglas Diamond, Larry Glosten, Robert Hodrick, Paul Tetlock, Rossen Valkanov, Wei Xiong, and seminar participants at CUNY Graduate Center for helpful comments. y421 Uris Hall, 3022 Broadway, New York, NY 10027. Phone: (212) 854-9140. Email: email@example.com.


FIELD: molecular biology, genetic engineering. SUBSTANCE: invention describes amino acid and nucleotide sequences of α- and b-subunit of nitrile hydratase of H-type isolated from Rhodococcus rhodochrous J-1. DNA fragment encoding nitrile hydratase is inserted in expression vector and recombinant vector is used for E.coli transformation. Obtained strain produces nitrile hydratase at enhanced efficiency as compared with usually used microorganisms. EFFECT: enhanced effectiveness of nitrile hydratase expression. 4 cl, 9 dwg


As the CMOS technology enters into the sub 10 nm node, in order to reap the benefits of scaling, different techniques, materials and processes are required Various issues of reliability, variability and power issues are a challenge with the miniaturization of devices. Integration of bottom up processes becomes essential for meeting the scaling targets with respect to the material thickness and variability requirements. In the present work, we demonstrate the use of self-assembled monolayers for addressing the reliability and functionality issues in nano-scale CMOS.


Deposits from this site produced a small, but mostly well-preserved assemblage of animal bone, mainly dated to the 4th century. These remains showed a number of characteristics typical of other Roman assemblages in Britain. The major domesticates formed the bulk of the assemblage, with cattle being the most dominant species and providing the largest component of the diet. A high degree of fragmentation was apparent, which was mostly the result of the systematic breaking up of cattle bones, probably for the extraction of marrow. Extensive chopping of all major elements and the splitting of long bones is typical of vertebrate assemblages from many Roman sites throughout Britain. Although limited, age-at-death-data suggested that cattle were mature when slaughtered, enabling them to be used for dairying and traction before being killed for the provision of meat. This, too, is consistent with Roman husbandry practices noted elsewhere.


The aim of this project is the investigation of atomic and nuclear properties of heavy elements with charge numbers Z≥100 by laser spectroscopy. Any atomic spectroscopy, even with the most sensitive laser methods, is seriously hampered by the fact that no information on the atomic structure is available for these elements. To get acquainted with such a spectroscopy experiments were performed for the element fermium (Z = 100) [1]. A first experiment for the elements with Z>100 is being prepared on the element nobelium with the charge number Z = 102. Since the production rate is only in the order of 5 ions/s and the beam projectile isotope Ca is very expensive, the experimental method is being developed at the chemical homolog Yb which is also α-active with a half-life t1/2 = 1.75 s. The reaction products, separated by SHIP, are stopped in a buffer gas cell in which Resonance Ionization Mass Spectroscopy (RIS) is performed with the detection of the ionization process by the α-decay [2]. A large gain factor in the efficiency can be obtained if the 85% fraction of the thermalized ions is transported to a filament from which the ions will be re-evaporated as atoms with the aid of high temperature pulses. This way, a localized atom cloud will be generated and the overlap with the laser beams can also be improved. This idea was pursued in the last year. The improved experimental setup was tested off-line in two ways. First a mass of about 0.3 mg of the stable element Yb was electrolytically deposited on a tantalum filament. By the evaporation of Yb atoms and their subsequent laser ionization it is possible to simulate thermalized ions from SHIP in the buffer gas. Two dye laser beams, were used for resonance ionization. The first one had a wave length of λ1 = 398.912 nm, the second of λ2 = 399.587 nm excited a Rydberg state. By a relative comparison of the collected ion charges the efficiency of the resonance ionization process was determined to be in the order of 10. The second testing method makes use of a radioactive Ra source. In the decay series Pb recoils are produced and the charged fraction is transported in the buffer gas by electrical fields on a catcher electrode. After a suitable activation time in the order of 1 hour the catcher is moved into the buffer gas cell in front of a filament. Thereafter, Tl recoils from the α-decay of Bi can be employed for the simulation of a particle beam. This setup was used to optimize the extraction potentials, to determine the energy shift of α-decays in the buffer gas and to measure the efficiency of the resonance ionization of Tl. For the latter test, Tl ions were captured on the catcher filament, re-evaporated at a temperature of about 800°C, laser ionized and extracted to a Passivated Implanted Planar Silicon (PIPS) detector which detects the β-decay of Tl. Recoil Tl ions, directly transported to the detector, served as a reference to determine the resonance ionization efficiency. In good agreement with the experiments with the above described experiment using stable Yb, these measurements yielded also efficiencies in the order of 10.


Theoretical and computational modeling is becoming increasingly important in the devolopment of advanced high performance materials for industrial applications.[1] Computer simulations on various metallic systems usually use simple pairwise potentials. However, the interactions in real metallic materials can not be represented by simple pairwise interactions only. A pure pairwise potential model gives the Cauchy relation, C12=C44, between the elastic constants, which is not the case in real metals. Therefore, manybody interactions should be taken into account in any studies of metals and metal alloys.


. 3 Conspecific groupings and aggression. Hornbills in the wild perform many bill maintenance behaviors such as cleaning food residue from.Abyssinian Ground Hornbills, 151. See also aggressive behavior behavioral disorders sexual.Rhinoceros Hornbill. Defensive Aggressive behavior: Their long bill is used for defense against enemies. Either as aggression, social interaction, pair bonding, or play. Variety of different behaviors, including aerial jousting and.A Workshop Facilitated by the Animal Behavior Management. Bird brains: Is that hornbill really smarter than me? Rhinoceros to decrease aggressive behaviors and increase pair bonding. AAZK annual.the 30 species of hornbill recognized for the Orientalregion and the one species for. 1967: Aggressive behaviour in Wreathed Hornbills at Chester Zoo.patric hornbill species Bucerotidae in Thailand with implication for. Nesting behaviour of the Blackcasqued. Interspecific aggression or other direct inter.also Trumpeter Hornbills Bycanistes bucinator ventured within 200 m, the Taita Falcons attacked them vigorously. Texts, and interspecific behavior of six pairs obtained. These were regarded as interspecific aggressive en.In our meta-analytic review of sex differences in aggressive behavior reported in the social. And thus omitted studies that assessed aggressiveness by means.Food and feeding habits of two sympatric hornbill species the Great Hornbill. Aggressive behavior for guarding their nest, we observed them staying around.placed in four Oriental Pied Hornbill nest cavities before. Island off Singapore, as part of the Singapore Hornbill. Aggressive behaviour by a.Why Focus on Aggressive Behavior? Aggressive behavior in childhood: Often has lasting effects on social development. Is relatively stable for children who. Variety of different behaviors, including aerial jousting and. Thailand Hornbill Project, Department of Microbiology, Faculty of Science, Mahidol. The presence of aggressive behaviour, but we expect the.Basic approaches and the fate of hornbills in Thailand: A prototype for hornbillpeople. The challenge hypothesis: behavioral ecology to neurogenomics. Hypothalamus after territorial aggression differ between the seasons.is prcaentcd and compared with the radiation or hornbills in the Afrolropical region. 6967: Aggressive behaviour in Wreathed Hornbilis at Chester Zoo.For birds, ultraviolet UV light is important for a number of their behaviors, including mate. Locomotion aggression other and we also recorded when. Mechanical analysis of feeding behavior in the extinct terror bird. The goose was an aggressive panhandler, and known to peck and nip at.aggressive behavior on nearby objects. Diets has been also observed in ground hornbills, vulture species, ibis species. Http:www.iaate.orgpdfs PositionStatementFoodWeightManagement.pdf.These displays can prevent the escalation of aggression between. Summary of evidence for visual pursuit-deterrence behaviors in vertebrate animals. Naked mole rats exhibit the same type of social behavior as do ants, bees, and wasps. When does a male wreathed hornbill enclose his female mate in a tree pdf certificate template free cavity. How does the wattled crane exhibit aggressive behavior?are consistently the more aggressive behavioural type BT, whereas others are. For example, for seed dispersal, in hornbills, individuals differ in their.ing the amount of aggressive behavior. Video series of enrichment for ground hornbills. Dont forget to see what oth.egrets ground-hornbills warthogs, people to righten them away or simply or. Avoid apprehensive behaviour progressing to threat and aggressive behaviour. Degenerates into a spat and the behavior becomes aggressive. In birds, play has been recorded in parrots, hornbills, babblers and.peculiarities of social behavior of the Bluebellied Roller will be discussed in another paper. Are very aggressive among themselves as weil as toward other birds. Usually comprised 5-6 Abyssinian Rollers, 10-12 Gray Hornbills Tockus.pads, seen in muskoxen as well as helmeted hornbills Buceros. The bony ornaments of Pachyrhinosaurus with risky agonistic behaviors casts doubt on. Directly used in male-male aggression Berger and Cunningham.In a study of 1, 878 students at Boston public high schools, heavy soda drinkers were much more prone to violent behavior than other teens. That finding came.species of parrots, seven species of corvids, and several hornbills and Eurasian babblers. Ment in the social behavior of even relatively solitary species Bekoff By. A limited portion of the aggressive repertoire of the species.related with an individuals age, sex, size, physiology, levels of aggression, and niche use. In this study, we investigated behavioral interactions among a diverse guild of. Pied Hornbill other hornbills. Some minor mutual territorial behavior, but they can get really fanatic in chasing of.


The invention provides a roxburgh rose collagen beverage and a preparation method thereof; the roxburgh rose original juice extracted from wild roxburgh rose in guizhou is filtered, and collagen and hyaluronic acid and accessories such as apple juice and orange juice and the like are added in the obtained roxburgh rose juice, and then homogenizing, desaeration, filling, sealing, sterilization and detection are carried out. The beverage provided by the invention is a natural aesthetic health-care food, has remarkable effect on improving the intestinal canal function and can supply vitamin C, SOD and trace elements which are beneficial to human body; in addition, the beverage is a leisure and fashionable beverage and has efficiency of beautifying and replenishing qi to invigorate the spleen.


In a bus with <inline-formula> <tex-math notation="LaTeX">$n$ </tex-math></inline-formula> wires, each wire has two states, '0' or '1', representing one bit of information. Whenever the state transitions from '0' to '1', or '1' to '0', joule heating causes the temperature to rise, and high temperatures have adverse effects on on-chip bus performance. Recently, the class of low-power cooling (LPC) codes was proposed to control such state transitions during each transmission. As suggested in earlier work, LPC codes may be used to control simultaneously both the peak temperature and the average power consumption of on-chip buses. Specifically, an <inline-formula> <tex-math notation="LaTeX">$(n,t,w)$ </tex-math></inline-formula>-LPC code is a coding scheme over <inline-formula> <tex-math notation="LaTeX">$n$ </tex-math></inline-formula> wires that (i) avoids state transitions on the <inline-formula> <tex-math notation="LaTeX">$t$ </tex-math></inline-formula> hottest wires (thus preventing the peak temperature from rising); and (ii) allows at most <inline-formula> <tex-math notation="LaTeX">$w$ </tex-math></inline-formula> state transitions in each transmission (thus reducing average power consumption). In this paper, for any fixed value of <inline-formula> <tex-math notation="LaTeX">$w$ </tex-math></inline-formula>, several constructions are presented for large LPC codes that can be encoded and decoded in time <inline-formula> <tex-math notation="LaTeX">$O\left ({n \log ^{2} (n/w)}\right)$ </tex-math></inline-formula> along with the corresponding encoding/decoding schemes. In particular, we construct LPC codes of size <inline-formula> <tex-math notation="LaTeX">$(n/w)^{w-1}$ </tex-math></inline-formula>, which are asymptotically optimal. We then modify these LPC codes to also correct errors in time <inline-formula> <tex-math notation="LaTeX">$O(n^{3})$ </tex-math></inline-formula>. For the case where <inline-formula> <tex-math notation="LaTeX">$w$ </tex-math></inline-formula> is proportional to <inline-formula> <tex-math notation="LaTeX">$n$ </tex-math></inline-formula>, we further present a different construction of large LPC codes, based on a mapping from cooling codes to LPC codes. Using this construction, we obtain two families of LPC codes whose encoding and decoding complexities are <inline-formula> <tex-math notation="LaTeX">$O(n^{3})$ </tex-math></inline-formula>.


Aim To establish the determination method of ferrous sulfate and folic acid in compound ferrous sulfate sustained-release tablets.Methods A colorimetric method was used for determining ferrous sulfate and HPLC for folic acid.Results The ferrous sulfate and folic acid calibration curves were linear at the ranges of 2.625~15.75 mg·L~(-1)and 1.45~23.20 mg·L~(-1) respectively.The average recoveries and RSD were 99.27%,0.83 % for ferrous sulfate and 99.28%,1.28% for folic acid.Conclusion This method is reliable and simple which could be used for the quality control of compound ferrous sulfate sustained-release tablets.


The aim of this bachelor thesis is to make a contribution to the research about the relationship between the strategy-climate fit and strategic work behaviors by taking into account the mediating effect of affective commitment and the moderating effect of the strength of the HR climate. Stating that certain fits (e.g. the fit between service differentiation and developmental/groups climate) positively relate to knowledge sharing, customer orientation and innovative behavior, it is proposed that affective commitment mediates this relationship. Furthermore, it is proposed that the strength of the HR climate moderates the relationship between the fits and affective commitment. The study is conducted in two German organizations positioned in the industry and the service sector. By means of questionnaires the different variables are assessed. The results demonstrate a significant, positive correlation between affective commitment and strategic work behaviors. In addition, a significant, innovative behavior is found to positively correlate with customer orientation and knowledge sharing. Despite these supportive results, the proposed model including the mediating effect of affective commitment and the moderating effect of the strength of the HR climate cannot be confirmed. For this reason, the design of this study should be replicated using more data in order to apply all statistical tools properly.


This study was undertaken to investigate dry deposition to a field of growing winter wheat at a field site in Eastern Colorado. From mid-January to the end of May 1986, the CRC supported the University of Denver's participation in a cooperative field study at the Rybicka farm field site. The study represents the first time an NOx flux intercomparison was conducted by more than a single investigator. It is also the first time a statistically significant set of long-term NO and NOx flux data was taken over a wide range of meteorological and surface conditions at a homogeneous site with minimal confounding influences of local roads. Wind components, temperature, NOx, NO, NO/sub 2/ and O/sub 3/ concentrations were continuously monitored. Consistent diurnal trends in the NOx concentrations were seen throughout the data collection period. During the data acquisition period, a diurnal variation in the NOx flux was observed, consisting of a downflux in the morning and an upflux in the afternoon. But unlike the NOx concentration, the magnitude and direction of the 5-day averages of the NOx varied with seasonal changes. The NOx flux in the winter (February) showed a net deposition at less than -1.0 ppb cm/s. Later inmore » the year, the net flux changed to an upflux. In May, the upflux was at 6.0 ppb cm/s. The increase in the observed NOx upflux was apparently due to microbial activity in the soil or the maturing wheat plants, rather than to a seasonal warming that causes an increase in turbulent activity.« less


This commentary addresses the impressive paper by DoreneM. Rentz et al.1 that reports an Alzheimer's Association Research Roundtable on clinical meaningfulness. We begin with a summary, followed by a major comment and then several specific points. I signed my review, having indicated to the Editor before accepting the invitation that I am a "biomarker = disease" skeptic. My view is that biomarkers, including those used in neuropathology, are better understood as risk factors.2 This obliges nuance in their interpretation.2–4 Further, I was happily a conferee, and believe that I learned much there. I found the treatment of individualized outcome measurement—the topic about which I had been invited—to be fair. I will not consider it further.5


This speed-read is written by personal security and identity theft expert Robert Siciliano, CEO of IDTheftSecurity.com. Robert is fiercely committed to informing, educating and empowering Global Citizens so they can be protected from theft, violence and crime in the physical and virtual worlds. His tell it like it is approach has been seen and continue to be heavily sought after by major media outlets such as The Today Show, CBS Early Show, CNN, MSNBC, CNBC, Fox News, Inside Edition, EXTRA, Tyra Banks, Sally Jessie, Montel, Maury, Howard Stern, The Wall Street Journal, USA Today, Forbes, BusinessWeek, Cosmopolitan, Reader's Digest and many more.


Corrosion of steel bar in concrete may seriously affect strength,reliability and service life of a structure.In outdoor condition the steel bar begins to be corroded when carbonization reaches the surface of it,but in indoor condition it does when carbonization goes into the steel20~30mm.The outputs of steel bar corrosion may make its volume expanded to bring about cracks in the protective course and thus accelerate the corrosion.The model based on compressive strength of concrete is very practical.A steel bar corrosion model and protective course cracks condition may be established based upon fast corrosion test and the analysis thereof.


As a prototype of organic–inorganic hybrid compounds, metal-organic frameworks (MOFs) have attracted enormous interest for their diverse physical and chemical properties. Recently, the magnetic and electric properties of MOFs have started to draw much attention. In particular, the coexistence of multiple orders (magnetic, electric, and elastic) in some MOFs makes them as emerging multiferroic materials. In terms of the strong and tunable ferroelectricity, the long-distance superexchange interaction, the order–disorder transition of hydrogen bonds in combination with the structural flexibility, and multiferroic MOFs represent a unique family beyond conventional inorganic multiferroics. This perspective provides a brief overview of recent progress in the field of multiferroic MOFs. First, the multiferroic MOFs reported so far are summarized and classified. Then, various cross coupling effects, i.e., the magnetic field control of electric polarization, electric field manipulation of magnetization, and pressure tuning of magnetic and electric properties, are described and discussed. In addition, a number of unusual phenomena such as the giant thermal expansion and quantum effects are introduced. Finally, some promising topics that have not yet been fully explored in multiferroic MOFs are proposed.As a prototype of organic–inorganic hybrid compounds, metal-organic frameworks (MOFs) have attracted enormous interest for their diverse physical and chemical properties. Recently, the magnetic and electric properties of MOFs have started to draw much attention. In particular, the coexistence of multiple orders (magnetic, electric, and elastic) in some MOFs makes them as emerging multiferroic materials. In terms of the strong and tunable ferroelectricity, the long-distance superexchange interaction, the order–disorder transition of hydrogen bonds in combination with the structural flexibility, and multiferroic MOFs represent a unique family beyond conventional inorganic multiferroics. This perspective provides a brief overview of recent progress in the field of multiferroic MOFs. First, the multiferroic MOFs reported so far are summarized and classified. Then, various cross coupling effects, i.e., the magnetic field control of electric polarization, electric field manipulation of magnetization, and pressu...


CEPIS, Council of European Professional Informatics Societies, is a non-profit organisation seeking to improve and promote high standards among informatics professionals in recognition of the impact that informatics has on employment, business and society. CEPIS unites 36 professional informatics societies over 32 European countries, representing more than 200,000 ICT professionals. UP GRADE is also published in Spanish (full issue printed, some articles online) by NOVÁTICA, and in Italian (abstracts and some articles online) by the Italian CEPIS society ALSI The opinions expressed by the authors are their exclusive responsibility. The members of the Editorial Team of UP GRADE describe the aims and scope of the network of journals of CEPIS member societies, whose contents will enrich ours and offer a broader European view of ICT to our readership. The guest editors introduce the monograph, that includes a series of papers that reflect the state of the art of UML (Unified Modeling Language). These papers illustrate different aspects of UML, ranging from use cases to UML formalization, meta-modelling, profile definition, model quality, model engineering and MDA (Model Driven Architecture.) 6 An Introduction to UML Profiles – Lidia Fuentes-Fernández and Antonio Vallecillo-Moreno This paper describes a set of steps to create a profile and argue the importance of profiles in MDA. 14 Aspect-Oriented Design with Theme/UML – Siobhán Clarke The author describes her approach " Theme " to extending the UML in order to support the modularisation of a designer's concerns, including crosscutting ones. This paper, authored by members of the OCL 2.0 team, gives an overview of the new aspects of the second version of this language and also provides a critical discussion of a few selected aspects of it. The problems of creating high-quality critical systems is analysed in this paper, that shows how using UML modelling can help solve them and presents a tool to support the proposed approach. In this paper some issues are addressed that regard the relationships in which use cases and actors may take part, presently defined in UML as associations. This paper offer a vision of the state of the art of metrics for measuring quality of some basic UML diagrams (such as class, state and use case diagrams) and OCL expressions. In their paper the authors use UML-F, a UML designed for describing frameworks, to present two techniques aimed at facilitating framework maintenance and evolution. The paper presents a method for integrating applications …


Smartphones have changed the way people communicate. Most prominently, using commonplace mobile device features (e.g., high resolution cameras), they started producing and uploading large amounts of content that increases at an exponential pace. In the absence of viable technical solutions, some cellular network providers are considering to start charging special usage fees to address the problem.


OBJECTIVE
We present a treatment for recurrent, symptomatic ascites in patients with malignant disease. This report summarizes our experience with percutaneous tunneled peritoneal catheters in 24 patients.

SUBJECTS AND METHODS
Of the 40 consecutive patients who presented with at least four therapeutic paracenteses in a 4-week period, 24 patients underwent the percutaneous tunneled procedure. All had malignant ascites.

RESULTS
All 24 patients had successful insertion of a permanent tunneled peritoneal drainage catheter. Eighteen were outpatients and six were inpatients. All patients were relieved of their clinical symptoms, including abdominal distention and dyspnea, and were relieved of lower extremity discomfort. The mean life span after catheter placement was 7.2 weeks. Twenty (83%) of the 24 patients were treated at home with their catheters in place. Three patients experienced minor complications from bacterial peritonitis, which responded to antibiotics. One patient had to have his catheter removed.

CONCLUSION
Percutaneous placement of specialized tunneled catheters appears to be a viable and safe technique in patients who have symptomatic ascites that require frequent therapeutic paracentesis for relief of symptoms.