: based on provincial level, this paper established research framework and estimation model of carbon emission inventory. It also estimated the carbon emission inventory of Jiangsu province from 2000 to 2008, and analyzed carbon reducing potential of Jiangsu province through scenario approach. the conclusions were as following: (1) Total carbon emission of Jiangsu province increased from 8005.29×10 4 t in 2000 to17426.22×10 4 t in 2008 with increasing rate of 118%, in which carbon emission from industrial energy consumption account for 86%.(2) Carbon emission intensity of per unit GDP of Jiangsu province decreased from 0.94t/Yuan RMB in 2000 to 0.75t/Yuan RMB in 2008, meanwhile per capita carbon emission increased form 1.09t in 2000 to 2.27t in 2008. (3) The amount of reduced carbon will be 6641×10 4 t and 19206×10 4 t in 2015 and 2020 respectively under low-carbon scenario, and the carbon reducing proportion will be reach 19% and 34% respectively. (4) In the "twelfth five-year planning" of Jiangsu province, carbon emission reduction in the sectors such as industrial and transportation energy consumption, waste burning and dumping should be strengthened, and provide technological support and demonstration effect for the development of low-carbon Jiangsu province, and decrease regional carbon emission intensity effectively.


In this issue, we are finalizing our journey to explore NF-κB—covering basic, translational, and clinical aspects in inflammation and cancer. The overall take-home message is that of complexity, that there still are vast opportunities that need to be taken advantage of, mechanisms of disease and drug actions that need to be elucidated—all with impact on drug and diagnostics development. Dr. Krakauer in her editorial captures the complexity of the NF-κB system positioned within a complex network with multiple pathways leading to NF-κB modulation in a sequential or simultaneous fashion. This complexity and pleiotropism warrants more understanding to enable new drug development efforts vis-à-vis targeting various facets of NF-κB, as well as new therapeutic means resulting in fine-tuning rather than stark signaling change to avoid side effects and optimize pharmacologic potency. Two articles in this issue continue the exploration of NF-κB pathway at the interface of inflammation and cancer from entirely distinct angles. Dr. Fraser illustrates the interplay between the G protein–coupled receptors (GPCRs) and the NF-κB signaling pathway; GPCRs represent the largest family of cellular receptors regulating cellular proliferation, differentiation, chemotaxis, inflammation, and with impact on cancer progression. Because of the downstream positioning of the NF-κB system relative to GPCRs, this opens up the possibility of modulating the NF-κB activity via targeting GPCRs, thus expanding the realm of the druggable targets in cancer and inflammation. Dr. Sarkar and his collaborators highlight the exciting evidence in support of the role of


Aim of this paper is to provide an overview of Alcatel Alenia Space-Italy (AAS-I) Spread-Spectrum Transponder platform placing emphasis on its advanced features for secure telemetry, tracking & command (TT&C) applications


This study examined the effects of China's one-child policy on two traditional aspects of Chinese family life: filial piety and patrilineality. Eighty-four graduating university seniors, who were part of the first cohort born under the onechild policy, were interviewed about their life plans. Comparisons between only children and those with siblings showed that only children were as likely to plan on helping their parents as were those with siblings and were more likely to intend to reside in the same city. The only children seemed to feel especially responsible for their parents' happiness because of their singleton status. Among only children and those with siblings, patrilineal norms seemed weak. Students'mentions of family structure to explain their decisions suggest that the one-child policy is undermining patrilineal norms.


Background: The most described oncogenes in lung cancer are those encoding for EGFR (epidermal growth factor receptor) and KRAS. The mutations of the gene KRAS have been described since two decades. In spite of that fact, the assessment of their implication in lung cancer remains debated. Aim: We aim to assess the real impact of the mutations of KRAS on the prognosis and treatment of non-small cell lung cancer through a mini review of the literature. Methods: We performed a mini-review of the literature through the pubmed site using the key-words: KRAS gene, KRAS mutations in lung cancer. Results: Through this review of the literature, we noticed the multiplicity of the studies dealing with this subject and the absence of consensus concerning the consequences of these mutations on the management of the patients. Conclusion: KRAS mutations play a key role in the carcinogenesis of lung cancer. In the presence of mutations, this way becomes autonomous and interacts with other ways mainly PI3K and MEK. A better knowledge of these mutations will enable a prediction of the answer to anti-EGFR therapy. Besides, other therapeutic targets will be explored in non responders' patients. the real time PCR…. New diagnostic techniques include ARMS, the SNaPshot and the next generation sequencing. All these methods present advantages and disadvantages in terms of cost, sensitivity and delay of response [4,5]. The direct sequencing represents the gold standard method for the diagnosis of KRAS mutations in routine despite its low sensitivity estimated to 20%. The HRM technique has a sensitivity of 5% but seems to be difficult in routine. Real time PCR is a sensitive technique with a sensitivity of 1-2%. Tuonenen and coworkers compared the DNA arrays to the real time PCR in the detection of EGFR, KRAS and BRAF mutations. They reported a good concordance between both techniques [6]. the SNaPshot technique has been reported to be sensitive necessitating only 10% of tumor cells. A about the detection of KRAS mutations with a sensitivity of 10% but this technique seems to be difficult to perform routinely [5]. Pyro-sequencing technique uses 4 enzymes (DNA polymerase, ATP sulfurylase, luciferase and apyrase) and 2 substrates (Adenosine 5´ PhosphoSulfate (APS) and luciferine). Pyro-sequencing is a quantitative method used routinely with a sensitivity of 5%. (Harvey rat sarcoma viral oncogene) and the oncogene viral N-ras viral (neuroblastoma RAS viral oncogene). These genes encode for a guanine triphosphate binding protein family inducing cell proliferation, differentiation and apoptosis and interacting with MAPK (mitogen-activated protein kinase) and STAT (signal transducer and activator of transcription and PI3K (phospho-inositide-3 kinase) pathways [2]. In non-small cell lung carcinomas, 90% of the mutations are localized in the KRAS gene. About 15% of the patients with non-small cell carcinomas


The inhibition behavior of 4-Aminoantipyrine on carbon steel in HCl solution was studied by weight loss testing,potentiodynamic polarization curvers and electrochemical impedance spectroscopy.The results show that the inhibition efficiency increased with the increase of 4-Aminoantipyrine concentration.4-Aminoantipyrine is a mix-type inhibitor which can inhibit the reaction of anode and cathode,and the standard free Gibbs energy of adsorption is-30.52 kJ·mol-1,which indicates that 4-Aminoantipyrine can adhere on carbon steel surface with a kind of spontaneous adsorption model between physical adsorption and chemical adsorption,and obeys Langmuir isotherm.


Patients can present with undiagnosed sleep disorders. Modest fatigue can impair their neurological, functional and psychological capacities. Four patients demonstrated improved functioning on modafinil, during the months required for a complete sleep evaluation, specialist consults and successful treatment. Sleep disorders increase morbidity or mortality until definitive diagnosis and full treatment. In four patients, modafinil was immediately useful as a bridging medication over 3-7 months until final successful diagnosis and treatment. Even one month of significant fatigue is unacceptable. For example, driving a motor vehicle is dangerous with some sleep disorders. Falling asleep driving or involuntary "minisleep" at the wheel is a common cause of motor vehicle accidents.1 In the United States, sleep causes at least 56, 000 motor vehicle crashes each year, resulting in 1, 550 deaths.2 Over a year, 10% of men and 4% of women admitted to falling asleep while driving.3 Insight into drowsiness can be flawed, lagging behind electroencephalographic and other evidence that the process of falling asleep has actually started.4 In clinical care, the patient may be sleepy or fatigued, but not a clear risk to drive or work. Further, many occupations do not allow for fatigue, sleepiness and errors, e.g., truck drivers, heavy construction operators, nurses dispensing medications, pilots, boat captains, military and police personnel using dangerous equipment, and childcare workers with children. Modafinil was used because it may be more selective than traditional stimulants, has a low abuse potential, is already used in many specific sleep disorders, and has a reasonable safety record. Modafinil's mechanism as a waking agent appears to be a more selective than amphetamine or methylphenidate in cats, 5 possibly causing less emotional side effects in humans, e.g., agitation and rebound depression. Perhaps due to this proposed selectivity, modafinil receives low ratings for abuse desirability, 6 and with a low solubility in water and instability at high temperatures, I.V. injections and smoking were less likely. 7 These are some reasons that modafinil might be considered in light of the non-specificity and addiction potential of traditional stimulants. Modafinil has cognitive benefits in aviation alertness and functioning. 8, 9 It decreases fatigue in narcolepsy, obstructive sleep apnea, Parkinson's disease, multiple sclerosis, stroke and fibromyalgia.10,11,12,13,14,15 Also, medically fragile patients seemed to tolerate modafinil. Our patients were much healthier than those treated with Parkinson's disease, stroke and multiple sclerosis. These private patients were all waiting for a sleep specialist appointment. They read handouts on the common use of modafinil, e.g., narcolepsy. However, they understood they were trying it for the off-label purpose of daytime sleepiness. Rare questions were answered to their satisfaction.


Along with the development of science and technology, especially internet of things (IOT), IOT-related products increasingly contribute to improving people's life. Among those products, it is impossible not to mention smarts city, internet of Vehicle devices and especially smart home, which are usually voice controlled. Therefore, voice processing technology is also in need of improvement. The article mainly focuses on processing human voice independently of text. In particular, Convolutional network (CNN) and Support Vector Machine (SVM) will be integrated to create Feature Building Machine. SVMs are often used in voice and image classification, which accordingly is a critical and swift data sorter. The article analyzes the advantages of the combination Deep Neural Network (DNN) and SVMs in voice recognition and is the foundation to develop devices for smart home. The experimental results, which was used in the standard Voxceleb database, demonstrate the superiority in sound recognition compared to traditional i-vector methods or other CNN methods.


The goal of this paper is to provide performance improvement and stability for satellite data correction of some distortions due to cloud or radiance through distributed processing on cluster. To do this, we proposed and implemented SGE(Sun Grid Engine) based distributed processing methods using local storages and a status table. In the verification, the experiment result revealed that the proposed system on seven nodes improved the processing speed by 138.81% as compare to the existing system and provided good stability as well. This result showed that the proposed distributed processing work is more appropriate to process CPU bound jobs than I/O bound jobs. We expect that the proposed system will give scientists improved analysis performance in various fields and near-real time analysis services.


The invention discloses a kind of artificial abortion's method for early warning based on MAC code and recognition of face, it specifically includes following steps: the first step, gathers the crucial crowd's face occurred in the range of specifying, and alerts;Second step, detecting customer terminal mobile phone hardware information;3rd step, uploads to high in the clouds by warning information;4th step, uploads to high in the clouds by the client hardware information detected;5th step, association face is got through with hardware information and is mated check and correction;6th step, high in the clouds pushes the result got through to Visualization Platform and big platform for data arrangement;7th step, Visualization Platform and big platform for data arrangement show whole system according to RUNTIME VIEW in the way of minute rank refreshing;8th step, early warning crowd being correlated with and warning message are reported to platform administrator, and automatic outdoor giant-screen and the client mobile phone that message is pushed to monitored area, play early warning effect.


The geochemical fingerprinting of produced water has been identified as a practical tool for operational applications in the petroleum industry. Provenance studies of produced water are essential to trace flow dynamics and reservoir compartmentalization in petroleum systems and to quantify fluid recovery rates from unconventional fracturing. Due to the fact that recovered oilfield water samples are frequently contaminated by operational fluids (i.e., oil-based mud, water-based mud, completion brines or stimulation fluids), representative samples for reservoir fluids have to be filtered from the geochemical data set of produced water. Besides the routine analysis of major elements (Na, Ca, Mg, K, Cl, SO4, HCO3), an enhanced geochemical monitoring program with selected minor and trace elements (i.e., B, Ba, Li, Sr), environmental isotopes (i.e., delta2H, delta18O, 87Sr/86Sr) and radiogenic isotopes (i.e., 3H, 14C) can provide in-depth information on the provenance of recovered oilfield water. Provenance studies of flowback water from hydraulic fracturing assets represent an enhanced method to assess the efficiency of the fracturing process by quantifying the recovered volume of originally injected fracturing fluid during the post-fracturing phase. The combination of gas recovery rates with geochemical flowback efficiency resulted in a practical tool to characterize the type and complexity of natural and induced fractures. Two cases studies showed that the combination of high gas recovery rates with low backflow efficiencies imply the presence of a complex system of natural and induced fractures. As a practical outcome, geochemical fingerprinting of recovered fluids can improve operational strategies for performed fracturing assets by avoiding water-pay zones, minimizing the amount of required fracturing fluids for injection purposes, and economizing the recycling process for recoverable flowback fluids. For the drilling of exploration or production wells, the presence of overpressured formations with a sudden water cut can frequently cause a technical challenge during well cementation. The design of a filtered geochemical database with regional fingerprints of formation water and groundwater zones is essential to identify the specific interval of water breakthrough for well plugging solutions. The routine geochemical analysis of reference water types, such as supply water and mud filtrate from the drilling process, is mandatory to quantify the potential flowback of applied drilling fluids.


The invention an activation solution and application of the activation solution in a magnesium-alloy chemically nickel-plated layer. The solutes in the activation solution include citric acid, potassium pyrophosphate and ammonium bifluoride, wherein the concentration of citric acid is 30-120g/L, the concentration of potassium pyrophosphate is 10-6g/L, and the concentration of ammonium bifluoride is 10-100g/L; the process of treating the magnesium-alloy chemically nickel-plated layer with the solution is as follows: the magnesium-alloy chemically nickel-plated layer is soaked in acetone or ethanol or is cleaned ultrasonically; the cleaned magnesium-alloy chemically nickel-plated layer is aired naturally; a strong-alkali deoiling solution is adopted to perform secondary deoiling on the surface of the magnesium-alloy chemically nickel-plated layer; two-stage or multi-stage running water is adopted to clean the surface of the magnesium-alloy chemically nickel-plated layer subjected to secondary deoiling; the cleaned magnesium-alloy chemically nickel-plated layer is activated for 1-10 min by the activation solution at 15-35 DEG C; copper plating, silver plating, gold plating and other follow-up plating operations are performed on the activated magnesium-alloy chemically nickel-plated layer.


In this paper, the author refers the problems on the determination of the interest owed in accordance with the article 78 of the United Nations on Contract...


The problem of constant-gain output feedback regulator design for linear systems with ill-conditioned dynamics is considered in the context of singular perturbation theory. A design approach is developed in which gains can be separately calculated to stabilize reduced-order slow and fast subsystem models. By employing the notion of combined control and observation spillover suppression, conditions are derived to assure that these gains will stabilize the full-order sytem, assuming sufficient frequency separation between the slow and fast subsystems. An optimal control design procedure is described in which the spillover suppression conditions are satisfied by adjoining penalty functions to the subsystem performance indices. The theory is demonstated in a controller design for a flexible space structure.


ABSTRACT This paper explores the relationship between the EU's current re-imagining as a global security actor and its stance as a global promoter of progressive gender norms. For this purpose, we analyse how gender and race are constitutive of the meanings of security and Europe in major EU security strategies, and how this relates to the way gender (equality) is addressed as a policy issue. We find that, in the context of waning liberal world order and manifold internal and external crises, EU security actorness is constructed through narratives of masculinisation that entail feminisation of the EU's own past as a "peace project" and "soft power"; Othering of non-EU spaces and subjects; colonial perspectives on the EU's role in the world as "White Man's burden" and the reconstruction of whiteness through notions of "neutral" masculinities associated with technocratic professionalism, superior knowledge production, and market rationality. This intersectional gendering of EU security limits the emancipatory potential of gender policy through the racialisation of Other women and the simultaneous invisibilisation of postcolonial structures of inequality. Our analysis provides the groundwork for addressing how and why the EUropean security project continues to reproduce intersectional power relations and insecurities, despite commitments to gender equality and non-discrimination.


The main purpose of this paper is to make three brushless DC motors as control object and based on relative coupling strategy to study synchronized control of multi-motor system.By using simulink to build multi-motor control system to study speed trace with different loads and anti-jamming character.Adopting to control system with DSP and CPLD to prove the validity of the strategy.The simulation and experimental results were illustrated to show a good reference in synchronized speed trace and dynamic performance of the multi-motor system with relative coupling strategy.


Exploration of the impact of taxation on the hours worked by married women with husbands present. Decomposition of the tax effect; Measurement of the variables; Estimation results; Computation of tax elasticities by race and over time. (Abstract copyright EBSCO.)


ABSTRACT  The United States has experienced a sharp rise in recent years in the number of heritage language (HL) bilinguals, students who speak a language other than English at home. Due to a lack of advanced language development in other settings, many of these students enroll in foreign language courses in their respective home languages. This paper reports on a program designed to promote heritage language and literacy development in one university-level HL course, Spanish for Native Speakers (SNS). The ten-week program involved two classes of mostly English-dominant SNS students participating in an experimental course that included a combination of the following elements: free voluntary reading (FVR) outside the classroom, in-class literature circles (small group book discussions), a survey of popular literature in Spanish, and individual inquiry learning projects. Three measures of the course were used to evaluate its success in terms of vocabulary acquisition, attitudes toward Spanish literacy development, and reading habits. The experimental group made significant gains in word knowledge, read more than a comparison group of SNS students, and exhibited positive attitudes toward Spanish literacy at the end of the ten-week course. The evidence in favor of FVR, theoretical justifications for the approach in SNS courses, and implications for redesigning heritage language curricula at the secondary and university levels are discussed.


This paper addresses the dilemma faced by the Kurds in Iraq: press for independence or sustain autonomy. In the wake of World War I, betrayed by the colonial rulers, the Kurds lost their prospect for independence. The disintegration of the Ottoman Empire was a precursor to a more rigorous Kurdish quest for statehood. Saddam Hussein's atrocities against the Kurds amounted to the de facto state of Kurdistan in northern Iraq. Despite considerable progress, polarized debates over the reconstruction of Iraq post 2003 have generated concerns over the probable emergence of an independent Kurdistan. Nevertheless, the Kurdish leaders have insisted upon autonomy within a federal Iraq and have rejected partition as a solution to Iraq's ethno-sectarian conflict. They believe autonomy serves their nationalist aspirations further in preserving regional self-governance.


Purpose – This study aims to examine the relationship between top‐performing US furniture manufacturers and industry's best manufacturing practices.Design/methodology/approach – In the past studies, best manufacturing practices were mostly determined using qualitative methods. In this paper, a quantitative evaluating method to determine best manufacturing practices was designed by taking into consideration qualitative criterions. A sample of 122 manufacturing practices was observed in six US furniture companies, two of them considered world‐class performers and the other four considered average. A logistic regression was used to examine the relationship between best manufacturing practices and top‐performing companies.Findings – Statistical analyses showed a positive relationship between top‐performing companies and use of best manufacturing practices by these companies. A database of best manufacturing practices was created and shared with the participant companies.Research limitations/implications – One...


This paper expounds the relationship between university library and multimedia teaching, and introduces the methods for developing the multimedia teaching of the library by utilizing the superiorities in the equipment and resources.


Objective To clonethe ORF of murine B cell activating factor of TNF family(BAFF),express in prokaryotic cells and purify the expressed product.Methods Total RNA was extracted from fresh spleen of mice,from which the ORF of BAFF was amplified by RT-PCR and cloned into vector pMAL-c2x.The constructed recombinant plasmid was transformed to E.coli Rosseta(DE3)for expression under induction of IPTG.The expressed product was purified by affinity chromatography and analyzed by Western blot.Results A cDNA fragment at length of about 930 bp was amplified by RT-PCR,of which the homology was 99.9% to the ORF cDNA sequence reported in GenBank.Restriction analysis proved that recombinant plasmid pMAL-c2x /BAFF ORF was constructed correctly.The relative molecular mass of expressed recombinant protein was about 76 500.The expression level reached a peak value after induction with IPTG at a final concentration of 0.9 mmol/L for 4 h.Target protein bands were observed in both supernatant and precipitate of ultrasonicated E.coli.The expressed product in soluble form contained 49% of total somatic protein.The purified recombinant protein reached a purity of 90% and a content of 0.9 mg/ml,and showed good reactogenicity.Conclusion Murine BAFF ORF was successfully cloned,expressed in prokaryotic cells and purified,which laid a foundation of further study on its biological function.


According to the United Nation Refugee Agency, it is estimated for 2015 a track worldwide of forced displacement exceeding 60 million. For the first time the number of forcibly displaced people is the highest level of people displaced since World War II (UNHCR, 2015). Among them, Syrian refugees became the largest refugee group since 2014 (3.9 million in 2014, and 4.2 million by mid-2015), replacing Afghanistan as the main source of refugees worldwide, as Afghan refugees had been the largest refugee group for three decades. Even though most Syrian refugees were hosted by neighboring countries such as Turkey, Lebanon and Jordan, the number of Syrian refugees applying for asylum in Europe steadily increased between 2011 and 2015. The statistical picture of the number of people seeking international protection in Europe is partially distorted because of the reported instances of the same individual being registered as asylum-seeker multiple times across the continent (UNHCR, 2015).
Germany has been the most sought-after final destination in the EU migrant in 2015 refugee inflow. In 2015, approximately nine hundred thousand migrants continued to pour into Germany as of 20 December 2015. From the migrants entering into Germany, approximately 500 000 have already been registered and requested asylum as of 30. December 2015 (Ministry of Foreign Affairs, 2015). In Germany, the right of asylum is not only anchored in the 1951 Geneva Convention on Refugees; it is also enshrined in the Constitution as a fundamental right. This is the unique fundamental right which is applicable only to foreigners. Asylum law has thus a special priority in Germany (Ministry of Foreign Affairs, 2015).


Introduction:
Multidrug-resistant tuberculosis (MDR TB) is TB that is resistant to at least two of the best anti-TB drugs, isoniazid (INH) and rifampicin (RMP). Over the past 15 years, however, incomplete TB treatments due to shortages of medicines and medical personnel, civil disruptions, and socioeconomic barriers for patients have led to a proliferation of strains of tuberculosis resistant to one or both of those medications. These drugs are considered first-line drugs and are used to treat all persons with TB disease. The purpose of this study is to determine MDR cases among new cases of pulmonary tuberculosis patients (PTB).

Methods and Materials: A cross-sectional study was conducted in patients suspected of PTB referring to Boo-Ali Hospital and TB clinic, two major referral centers in Zahedan, South-Eastern Iran during a period of 8 month. All sputum specimens were cultured in Lowenstein media and then antibiogram was performed to detect MDR cases in new PTB patients.

Results: Among 63 culture positive sputum specimens from 63 new cases of PTB, 3(4.8 %) were resistant to INH and 2(3.2%) resistant to RMP. Two cases (3.2%) were resistant to both INH and RMP so they were considered as MDR.

Conclusion: Resistance to both INH and RMP was a major clinical problem, especially in new cases of PTB. As sputum culture for TB does not performed for TB patients prior the beginning of anti-TB treatment, case finding of MDR by routine culture in the beginning of treatment is crucial for preventing the spread of MDR species into the community.


A comprehensive millimeter-wave calibration development and verification approach for on-wafer SOLT (Short-Open-Load-Through) standards is presented. Multiline TRL calibration procedures as well as EM simulations are used to develop initial SOLT calibration models which include the effects due to dispersion, metallization thickness, and distributed load. The models are then verified with offset open and load structures which cover all regions of the Smith chart in a frequency band. Theoretical and experimental verification of offset structures in K, Q, and V bands demonstrate good accuracy and repeatability of measurements.


In anesthetized cats efferent as well as afferent activity has been recorded in the kidney nerves. Pulse synchronous bursts of efferent impulses could regularly be recorded which after vagotomy and baroreceptor denervation were augmented and changed into a continuous type of discharge. The efferent activity could be modified by electrical stimulation of peripheral sensory nerves. It was inhibited by elevation of systemic blood pressure by i.v. noradrenaline injection, and greatly increased by lowering of blood pressure by i.v. acethylcholine. In the same nerves afferent activity also occurred, in a few instances spontaneously, but more often after elevation of renal vein pressure, elevation of arterial perfusion pressure (by pump), mechanical pressure applied to the hilus area or local dilution of the blood by close intra-arterial injection of Ringer solution. Local ischemia for one minute or less elicited intense afferent activity. The results indicate that venous distension and increased subcapsular pressure are adequate stimuli for these afferent responses and that more than one kind of fibers are engaged in the afferent response. The functional significance of the afferent activity remains to be determined.


Mycelium growth rate method was used to determine the indoor virulence of Boscalid,Jinggangmycin and Hexaconazole against Rhizoctonia solani Kuhn,and these fungicides were also applied to control rice sheath blight in the field.The results showed that the EC50 values of Boscalid,Jinggangmycin and Hexaconazole were 1.0692,96.2859 and 0.0240 μg/mL,respectively.On the 14th day after the second spraying,the control efficiency of 50% Boscalid WDG 600-times dilute solution against rice sheath blight was 63.53%,which was significantly lower than that of the control fungicides 20% Jinggangmycin A WP 1500-times and 5% Hexaconazole SC 600-times dilution.


The hardware and software system of the automatic coding control system in planography was introduced.It focused on analyzing the problems which the system faces on and their solutions.The usage of color sensor TCS230 is described in detail.


INTRODUCTION: Coronary Artery Disease (CAD) is the major cause of morbidity and mortality throughout the world. The pattern of Coronary artery disease is changing in India which occurs a decade earlier than the other countries, The highest proportion of cases with rst acute myocardial infarction at age 40 years or younger was in men from the Middle East (12·6%), Africa (10·9%), and south Asia (9·7%) and the lowest proportion was in women from China and Hong Kong (1·2%), South 1 America (1·0%), and central and eastern Europe (0·9%) . The risk in India is 3-4 times commoner than Americans, 20 times higher than Japanese. In India myocardial infarction is becoming more common in young patients and often having triple vessel disease. Reinfarction rate 2 is three times higher and two times higher rate of mortality in india . The risk factor concept implies that a person having one risk factor is likely to develop clinical atherosclerotic event and more do so in patients with multiple risk factors.


A double porosity model was presented for the biofluid flow in the liver lobule, where the sinusoid and the Disse space were treated as two porous media, and the blood and tissue fluid flow in them were modelled according Darcy's law. The flow field for specific condition was solved by the FEM technique. The flow and exchange patterns of blood and tissue fluid were revealed.


Introduction The recovery of patients after COVID-19 has been poorly described. Related coronavirus infections (SARS-COV1 and MERS) have protracted recovery time-courses with significant respiratory morbidity,1 suggesting the same may be true for COVID-19. A service evaluation was therefore undertaken to evaluate the short-term effects of COVID-19. Methods Respiratory specialist doctors conducted structured telephone consultations of patients admitted between 17th March 2020 and 2nd May 2020 with a diagnosis of COVID-19 pneumonia at a teaching hospital. Using time from discharge patients were allocated into 3 groups: 3–4 weeks, 4–5 weeks and 5+. Patients were asked to recall acute COVID-19 symptoms, current symptoms, activity levels, and exercise capacity after discharge. Exercise capacity was quantified by self-assessment of walking distance on flat (metres), stairs (flights). Patient reported outcome measures (MRC dyspnoea scale and WHO performance status) were also collated. Results A total of 102 patients were screened, 70 were included in the study, with the rest being unreachable (n=32) Cough, dyspnoea, fever and lethargy were the most common symptoms at time of admission. All these symptoms, except lethargy, improved following discharge (figure 1). Prevalence in the 5+ week cohort of other symptoms is as follows: dyspnoea 35.7%, cough 11.5%, fever 0%; however, 70% of patients had at least 1 symptom 5 weeks after discharge. Self-reported exercise capacity and MRC dyspnoea score also improved after discharge. Despite this 21.4% of patients had a persistent impairment in walking ability on the flat, 17.8% in stair-climbing with 28.5% persistent deficit in MRC dyspnoea score after 5 weeks. In contrast 40% of patients had a deficit in WHO performance status and this was not affected by time after discharge. In conclusion patients did improve following discharge from hospital for COVID-19 pneumonia, however many were left with residual symptoms and a functional deficit in short term (5 weeks). It remains to be seen whether this results in long term health problems. *highlights joint authorship Reference Hui DS, Wong KT, Ko FW, et al. The 1-year impact of severe acute respiratory syndrome on pulmonary function, exercise capacity, and quality of life in a cohort of survivors. Chest. 2005;128(4):2247–2261.


This paper takes 288 college students of Qujing Normal University as the research object,and takes Interaction Anxiousness Scale(IAS)as the research instrument.By using SPSS 13.0,this paper studied the current situation of the social anxiety of students in Qujing Normal University,and analyzed the causes of the social anxiety,which can provide a scientific basis for the student management and students' psychiatric consultation.


Current-efficient, fast-transient reconfigurable low-dropout regulator (LDO) is proposed for the wireless sensor network (WSN) system. The proposed LDO is designed and simulated in a 65 nm CMOS process showing the 3 key features: 1) a reconfigurable LDO architecture to achieve both low quiescent current (IQ) and wide bandwidth by adaptively adjusting to different load current conditions, 2) ultra-low-IQ and high PSR regulator for light-load efficient operation utilizing the gain boosting scheme within the flipped voltage follower loop, and 3) fast transient regulator for robust heavy-load operation with level-shifted impedance attenuation buffer (IAB) to reduce the supply ripples generated by wireless transceiver. The proposed LDO shows the state-of-the-art 93.8% current efficiency in the load condition of 1 μΑ, and achieves 0.672 ns response time even with 10 ns load transition.


The implementation of the National Health Insurance in South Africa is a noble attempt to address the inequities and scarcities of healthcare resources in the country. However, while South Africa's status as a developing country does not preclude the success of universal healthcare, as evidenced by certain international models, its success is threatened by corruption, mismanagement of resources, and poor-quality institutions. Rather than build a new system on poor foundations, existing facilities need to be overhauled. Increased transparency, as well as improvement in challenges such as cleanliness, personnel attitudes, and long waiting times may secure public 'buy-in'. Without these and other changes, public confidence will not be inspired – and, even more importantly, the system may fail in its goal of bringing about equitable resource allocation and improved healthcare.


Extracted from text ... A total of eight fire instructors from the City of Cape
Town Fire and Emergency Services have beaten
incredible odds in becoming the first South Africans
to complete Compartment Fire Behavioural training.
Even though the 'back draught' and 'flashover' phenomena
have been taught locally as per the IFSAC curriculum, the
instructors were determined to receive training on these
phenomena at the Moreton-In-Marsh Fire Service College, in
the United Kingdom. The training will be shared in South
Africa.
The group includes the writer, Greg Carollissen, Joey
Johnston, Mervyn Nefdt, Bernard Sauls, Barry Tucker, Dean
Williams and Jacques Laubscher.
The instructors' ..


The purpose of this essay is to discuss how Brazil has invested in diversification of its energy matrix to support the diplomatic discourse, in recent years, that defended new and less polluting resources over the current global energy paradigm that is based on the use of oil. In this way, we will analyze the latest available data provided by the government agencies and we will confront this information to the use of few clean resources explored in the country. We concluded that Brazil still has a framework of energy dependence. However, we believe that Brazilian diplomacy played the main role of encouraging other countries to think about alternative possibilities to the current energy paradigm taking into account their possible contribution to reduce greenhouse effect and to reduce damage to the environmental impact on the globe.


The Catholic Diocese of Daejeon has published two volumes of the letters of the priests who served at its churches in the early twentieth century. This invaluable information may be used to gain an important insight on the history of Catholic church of the Chungcheong region. This paper tries to analyse the correspondence of the clergy of Old Hapdeok Catholic Church, which occupies an important place in the history of the Catholic Diocese of Daejeon. Among the letters of the clergy of the Old Hapdeok Church, those of two Korean priests are fairly simple and not much of interest. However, the correspondence by three of the four French fathers, who served at the church mostly in the first half of the twentieth century, is very important in terms of its volume and contents and thus becomes the main subject of my analysis. The result shows that the interests and activities of these priests played a major role in the development of this particular parish. The correspondence of the priests of the Hapdeok church can be chronologically divided into three phases. The first phase is the period when Father Curlier laid foundation, literally and figuratively, of the Hapdeok Parish. He recognized his role as a missionary and tried his best to understand the situation of the area and status of his parishioners. In the second phase, Father Krempff searched for the economic basis of the church and focused on the external growth of his parish. He was deeply interested in the procurement of the land for the Old Hapdeok Church. It would provide help for the poor parishioners of the church and financial resources for the church. As a result, the Old Hapdeok Church became the substantial center of the Catholic churches of the Naepo area. In the third phase, Father Perrin established the religious foundation of the Old Hapdeok Church He paid much attention on the improvement of the religious life of his parishioners. He tackled many issues of his parishioners and devised new changes for the church. Father Perrin made his best efforts for the internal replenishment of the Old Hapdeok Church.


This article explores a model of Vijnānavāda generally known as the eight consciousnesses, which relates to understanding consciousness itself from the Vijnānavāda perspective. The model is mainly based on the description in the 'Verses Delineating the Eight Consciousnesses'. According to the eight-consciousness model, our entire consciousness involves the eye, ear, nose, tongue, body, mental consciousness, the manas and the ālayavijnāna. These components are presented beginning with the single mind through the increasing complexity of the process of consciousness. In this article, this model is examined as a potential theoretical resource that could guide insight, knowledge and enlightenment. Herein, it is expounded how the eight-consciousness model can increase our understanding of ethical decision making and develop a perspective that can facilitate enlightenment. This paper does not treat a very dense and complex doctrine of Vijnānavāda. However, when considering the actions and intentions that occur in the mind, these investigations represent the transformation of consciousness into wisdom.


This paper considers the potential for critical race theory (CRT) to enhance educational studies and to improve schooling opportunities for students of color. The author argues that CRT and qualitative educational research, jointly used, would provide a powerful critique of current ''colorblind'' educational policies which unfairly privilege whites. The author asserts that CRT could be beneficially used to inform whites about injusticesagainst students of color and to inspire new policies that would support the needs of diverse students. The author concludes that CRT could significantly aid efforts to make education more equitable.


Diverse narratives and practices concerned with 'vulnerability' increasingly inform how a range of social issues are understood and addressed, yet the subtle creep of the notion into various governance arenas has tended to slip by unnoticed. This paper explores the role of vulnerability in responding to longstanding and on-going dilemmas about social precariousness and harm. Drawing on in-depth qualitative research into how vulnerability was operationalised in services for 'vulnerable' young people in an English city, prominent narratives of vulnerability are traced, which operate in relation to a variety of often-dissonant service user responses. The paper shows the governance of vulnerability as a dynamic process; informed by policy developments and wider beliefs about the behaviours of 'problem' populations, interpreted and modified by interactions between practitioners and young people, and in turn shaping lived experiences of vulnerability. Patterns in this process illuminate how vulnerability narratives reshape long-running tensions at the heart of social welfare interventions between a drive to provide services that might mitigate social precariousness and an impetus towards regulating behaviour. The paper argues that although gesturing to inclusivity, the governance of vulnerability elaborates power dynamics and social divisions in new ways. Resulting outcomes are evidently varied and fluid, holding the promise of further social change.


A time resolved in-situ synchrotron X-ray powder diffraction study of hydrofluorocarbon (HFC)-134 (CF2HCF2H) and -134a (CF3CFH2) adsorption on NaY has been performed, as a function of the temperatu...


Patches of several transverse sand bars have been observed in the surf zone of open beaches spaced with a remarkable alongshore periodicity (from 20 to 200 m). A transverse bar is an elongated accumulation of sand attached to the low-tide shoreline that extends inside the surf zone with an oblique orientation up to 1 m depth. Due to the preferred breaking of waves at shallow areas, the white surface rollers over the bars are the clearest signal in the video-images that are collected hourly at different sites in the world. More than 40 events of formation and evolution of bar patches were recently described at Noordwijk beach, the Netherlands, using this technique. Bar migration and shape, with the crests deviating from the shore-normal against the alongshore current flow (up-current orientation), were evaluated. Wave conditions during bar presence were also determined.


Crisis communication is an integral aspect of public relations that can have either positive or negative repercussions based upon the action that an organization responds. The manner in which an organization handles a crisis determines financial implications that may ensue, public perception and reputation of the organization, as well as the overall success or failure of the organization in the future. Consequently, Timothy Coombs asserts that the best crisis communication practice is to respond quickly, accurately, and consistently (Coombs, 2010: 28). Other scholars concur and add supplementary techniques which emphasize preparedness and responsibility. The present study was conducted to identify models of best practices for crisis management and to apply these models to analyze the effectiveness of BP's response to the 2010 Gulf of Mexico oil spill. A content analysis of 164 articles from three newspapers, The Times Picayune, The New York Times, and The Herald (United Kingdom), was conducted to examine how BP responded to the crisis in the Gulf, as well as to compare differences in coverage of the crisis and response among the three newspapers. Results reveal that BP's response incorporated both best practices of crisis communication, as well as crisis responses that could be categorized as unethical. Such unethical responses included evasion of responsibility, denial, and scapegoating, while effective crisis communication tactics consisted of updating the public in a clear, concise manner. Further results and implications for international crisis communication practices will be described. Communicating During Crisis 8 CHAPTER ONE: RATIONALE Introduction to Crisis Communication Crises are inevitable. It is the manner in which an organization handles such crises that determines how the public will respond. When an organization's negligent actions cause harm to humans, the environment, or the economy, public outrage is unavoidable and deserved. Therefore, it is in an organization's best interest to react responsibly in order to prevent future harm. No matter how much an organization prepares in advance for a crisis or how efficiently it responds after a crisis has occurred, the possibility of reputational damage or serious financial loss still exists. Therefore, crisis communication in the field of public relations is an area that is essential to the success of any organization. Understanding how to plan for and effectively manage crises is pivotal. A contemporary example of a crisis facing an organization is the 2010 BP oil spill in the Gulf of Mexico. This particular crisis began on April 20, 2010 with an explosion and fire on the BP-licensed Transocean drilling rig Deepwater Horizon, followed two days later by the sinking of the Deepwater Horizon rig and reports of a five-mile-long oil slick. On April 24, oil was officially found leaking from BP's well in the Gulf, spawning a flurry of governmental, environmental, and media attention. Over the course of several months, the government, scientists, environmentalists, and Gulf residents fought to combat the leaking well and reduce the impact that the constant flow of oil would have upon the economy of the Gulf and the ecology of the area. Meanwhile, BP executives struggled to respond to the crisis appropriately, protect corporate stock and profits, manage changes in leadership, prepare for inevitable litigation, as well as salvage its public reputation. After waging a full-on battle with the well, BP announced that it was officially sealed on September 19, but not without continued scrutiny from a critical Communicating During Crisis 9 public audience (Alter, 2010; Casale, 2010; Crowley, 2010; Dudley, 2010; Gandel, 2010; Gray and Walsh, 2010; Guardian.co.uk, 2010; Hayes, 2010; Houck, 2010; Klein, 2010; Nijhuis, 2010; Smith, 2010; Weber, 2010). The BP oil spill serves as the focus for the present study, as it offers a contemporary case for viewing corporate crisis communication in action. Before corporate crisis communication can be studied empirically, however, it is important to understand this topic more broadly: to define and describe what constitutes a crisis and its stages; to outline relevant theoretical frameworks; and finally, to provide a rubric for identifying unethical and ethical crisis communication practices.


SPlCE-compatible modeling with generalized lumped devices is used to simulate the spatial and time dependence of photogenerated carriers with standard circuit simulators. Equivalent voltages and currents are used in place of minority carrier excess concentrations and minority carrier currents respectively. The initial light-induced excess carrier concentration in silicon is accounted by means of distributed external voltage sources. Generation, propagation and collection of these minority carriers is analyzed for three pertinent structures and compared with TCAD numerical simulations.


For the isotopic blend of polystyrene (PS) PS/deutero PS (M=106 dalton), the Flory–Huggins interaction parameter χ(φ,T) was determined by means of the structure factor S(Q) measured by small angle neutron scattering (SANS). From χ(φ,T), the miscibility gap and the corresponding spinodal line was evaluated with a critical temperature of 130 °C. Decomposition in the miscibility gap is extremely slow due to the critical slowing down and due to a glass transition 30 K below Tc. Furthermore, the transition of the homogeneous blend between two temperatures was investigated by SANS. The interdiffusion constant of the two isotopic species was determined from these experiments. Our results approach the Cahn–Hilliard–Cook theory only in the limit of small wavenumbers of the fluctuations. Three weeks after annealing the sample, demixing was observed in the predicted two‐phase region.


Background: Tofacitinib is an oral JAK inhibitor for the treatment of RA. Pain is the most common symptom reported by patients (pts) with RA,1,2 thus reduction of pain is an important treatment goal. Objectives: To evaluate the effect of tofacitinib monotherapy ± pain medication on pain in pts with RA. Methods: This pooled post hoc analysis included pts who received tofacitinib 5 mg BID monotherapy (ie without csDMARDs) in Phase (P)2 (NCT00550446), P3 (ORAL Solo; NCT00814307) and P3b/4 (ORAL Strategy; NCT02187055) studies. Pts were stratified by concomitant use of 'any pain therapy' (opioids, plain analgesics [eg acetaminophen], NSAIDs or glucocorticoids [GC; ≤10 mg of prednisone or equivalent per day]), 'pure analgesics' (opioids or plain analgesics) and 'adjuvant analgesics' (NSAIDs or GC). Pts receiving pain medication at baseline (BL) maintained a stable dose during the studies; opioid and/or acetaminophen dose could be increased as rescue therapy. Efficacy outcomes were assessed at Month (M)3 and M6: change from BL (δ) in Pt Assessment of Pain (Pain; visual analogue scale [VAS]) and δPain stratified by DAS28-4(ESR)-defined low disease activity (LDA; ≤3.2) status at M3 and M6. Results: Of 676 pts who received tofacitinib 5 mg BID monotherapy, 604 (89%) received 'any pain therapy', 141 (21%) received 'pure analgesics' and 589 (87%) received 'adjuvant analgesics'. Demographics and BL disease characteristics, including disease activity and Pain VAS, were generally similar when stratified by use/type of pain medication. Reductions in pain (δPain VAS) at M3 and M6 were generally similar for pts who received tofacitinib with 'any pain therapy' vs those who did not receive 'any pain therapy' (Figure 1a). There was a trend for a numerically greater reduction in pain at M3 and M6 in pts who received tofacitinib with 'any pain therapy' and who achieved LDA at M3 and M6 vs those who received tofacitinib with 'any pain therapy' and did not achieve LDA (95% CI overlapped; Figure 1b). By contrast, pain reductions were similar for pts who received tofacitinib without 'any pain therapy', irrespective of LDA status. Similar trends were seen when pts were stratified by use of 'pure analgesics' and 'adjuvant analgesics' (data not shown). Conclusion: In this pooled post hoc analysis, pain reduction was similar in pts with RA receiving tofacitinib, regardless of pain medication use. Pain reduction was similar in pts receiving tofacitinib without 'any pain therapy', irrespective of LDA status. These results should be interpreted with caution, as pain medication could be used as rescue therapy, few pts received tofacitinib without 'any pain therapy', and confounding by indication cannot be excluded. Further analyses are required to explore the impact of tofacitinib on the relationship between reductions in pain and disease activity. References [1] Walsh DA, McWilliams DF. Curr Pain Headache Rep 2012; 16: 509-17. [2] American College of Rheumatology Pain Management Task Force. Arthritis Care Res (Hoboken) 2010; 62: 590-9. Acknowledgement: Study sponsored by Pfizer Inc. Medical writing support was provided by Sarah Piggott of CMC Connect and funded by Pfizer Inc.Figure 1 Disclosure of Interests: Peter C. Taylor Grant/research support from: Celgene, Galapagos, Eli Lilly, UCB, Consultant for: AbbVie, Galapagos, Gilead, Eli Lilly, Pfizer Inc, Mart van de Laar Grant/research support from: AbbVie, Eli Lilly, Janssen-Cilag, Merck Inc, Pfizer Inc, Sanofi Genzyme, Speakers bureau: Eli Lilly, Pfizer Inc, Jeffrey R. Curtis Grant/research support from: Abbvie, Amgen, BMS, Corrona, Janssen, Lilly, Myriad, Pfizer, Roche/Genentech, UCB, Crescendo Bioscience Inc., Consultant for: Abbvie, Amgen, BMS, Corrona, Janssen, Lilly, Myriad, Pfizer, Roche/Genentech, UCB, Crescendo Bioscience Inc., Valderilio F Azevedo Grant/research support from: AbbVie, GSK, Janssen, Merck Serono, Novartis, Pfizer Inc, UCB, Consultant for: AbbVie, GSK, Janssen, Merck Serono, Novartis, Pfizer Inc, UCB, Jose Luis Rivas Shareholder of: Pfizer Inc, Employee of: Pfizer Inc, Palle Dahl Shareholder of: Pfizer Inc, Employee of: Pfizer Inc, Lisy Wang Shareholder of: Pfizer Inc, Employee of: Pfizer Inc, Noriko Iikuni Shareholder of: Pfizer Inc, Employee of: Pfizer Inc, Harry Shi Shareholder of: Pfizer Inc, Employee of: Pfizer Inc, John Woolcott Shareholder of: Pfizer Inc, Employee of: Pfizer Inc, Salim Benkhalifa Shareholder of: Pfizer SAS, Employee of: Pfizer SAS, Juan Jose Gomez-Reino Grant/research support from: Biogen, Gilead, Eli Lilly, Merck Sharp & Dohme, Pfizer, Roche, Consultant for: Biogen, Gilead, Eli Lilly, Merck Sharp & Dohme, Pfizer, Roche, maxime dougados Grant/research support from: Eli Lilly and Company, Pfizer, AbbVie, and UCB Pharma, Consultant for: Eli Lilly and Company, Pfizer, AbbVie, and UCB Pharma


A selected group of reported tests of chemical additives in actual geothermal fluids are reviewed and evaluated to summarize the status of chemical scale-control testing and identify information and testing needs. The task distinguishes between scale control in the cooling system of a flash plant and elsewhere in the utilization system due to the essentially different operating environments involved. Additives for non-cooling geothermal fluids are discussed by scale type: silica, carbonate, and sulfide.


A mask assembly or connection point with a mask assembly includes a mask seal, and a mask shell which holds the mask seal. In some constructions, the mask assembly is built to be fully lower than a nose of a face of a user positioned, and to provide an exposed nose of the user. The mask seal includes one or more features, the / n, so that a relative movement between them is possible, the movement of the nose portion and the mouth portion decoupled / at least about a longitudinal axis extending in the direction from front to back of the mask seal. In some constructions, the connection points assembly includes a restraining arrangement that limits a movement of the upper portion of the mask seal.


The objective of this study was to examine the association between the scores of the Children's Eating Behaviour Questionnaire (CEBQ) and BMI in a sample of Portuguese children. Using a cross-sectional design, a sample of 240 children (123 females and 117 males) aged 3–13 years were recruited from clinic and community-based settings. Parents completed the CEBQ to indicate their child's eating style for three 'food approach' and four 'food avoidant' sub-scales. Factor analyses revealed an underlying structure similar to the original CEBQ. Children's height and weight were measured to calculate BMI and Centre for Disease Control BMI z-scores. Hierarchical regression analyses controlling for gender, age and socioeconomic status indicated that all CEBQ sub-scales were significantly associated with BMI z-scores (P = 0·03 to < 0·001). Food approach scales were positively related to BMI z-scores (β = 0·33–0·51) and food avoidance negatively related (β = − 0·17 to − 0·46). Our results support the use of the CEBQ to further understand eating style as a behavioural pathway to obesity.


Yeats has dealt with sexuality and the dead in his poems throughout his poetic career. An examination of his use of sexuality and the dead leads us to see that the poet employs them as a means of conveying his poetic, spiritual, and political message. In his early years, Yeats turns to sexual images to entice one to the world of the spirits. In his middle years, Yeats tries to revive the fallen Irish heroes in the collective Irish memory through sexual imagery. In his later years, Yeats elevates the image of sexuality to the level of a vision through which political, social, and religious divisions are dissolved and reconciled.


We present a case with acute radiation-induced hepatic injury using chondroitin sulfate iron colloid (CSIS)-enhanced MRI. Uptake of CSIC was decreased in the irradiated portion of the liver. CSIC-enhanced MRI is useful for obtaining information on the function of the reticuloendothelial system and demarcates between irradiated and nonirradiated zones.


Natural Resources (NRs) underpin all human material productivity. Their scope is both transboundary and transgenerational. As such they transcend authority conventionally associated with governments and with individual corporations, provoking well-described imperfections of both. And, they accumulate effects of marginal decisions, across boundaries and over time. NR availability constrains opportunity to realize Human Rights recognized in the Universal Declaration, related


Cohen's paper (this issue) is discussed from a temporal persepective in order to query the place of psychic movement in nonsymbolic, "gestational" states and in treatment, and the relationship of these to personality development. The question of unconscious psychotic hostility to change is raised. The discussant queries the relevance of "merger" in "objectless intersubjectivity" in the context of the "systemic interchange" emphasized by the author, where it seems that the process of "interchange" is prior. Finally, the discussant raises the question of the role of primordial, "live" silence in gestation and in treatment.


Background Metastatic uveal melanoma (MUM) is associated with a poor prognosis, with a median overall survival (OS) of 4–15 months. Despite new insights into the genetic and molecular background of MUM, satisfactory systemic treatment approaches are currently lacking. The study results of innovative treatment strategies are urgently needed. Patients and Methods This was a retrospective case series of 8 patients with MUM managed at the University of Cincinnati between January 2015 and January 2018. The immune-related Response Evaluation Criteria in Solid Tumors (irRECIST) 1.1 criteria were used for patient evaluation, and magnetic resonance imaging was used for evaluation at treatment checkpoints. Objective To assess the clinical outcome of patients with MUM treated with a combination of checkpoint inhibitors. Results The series included eight patients, six men and two women, with MUM. Their median age at MUM diagnosis was 69 (range, 55–77) years. All patients were treated with ipilimumab and nivolumab combination along with transarterial chemoembolization (TACE), followed by nivolumab maintenance and monthly TACE procedures. The majority of patients had a partial response or stable disease. Two of the patients had partial response, while four others had stable disease. Two other patients experienced disease progression. Conclusion We report the outcomes of eight patients with MUM treated with the combination of ipilimumab and nivolumab. We report the clinical outcome and toxicity associated with this treatment approach. Further studies are warranted to explore immunotherapy in MUM. These findings support the consideration of immunotherapy in MUM.


The use of ultrasound technique to obtain the liquid film thickness was investigated. Ultrasound imaging is a technique that uses high frequency sound waves to produce precise images of structures. Ultrasound imaging is based on the same principle as SONAR (Sound Navigation and Ranging) during which a transducer capable of generating and receiving high frequency sound waves, sends pulses of sound waves into the interrogation area and the sound reflected back (echo) form any interface (such as water air interface) within the interrogation plane is obtained by the transducer. The time taken for the sound wave to travel from the transducer surface to the water air interface is obtained from the delay of the echo signal with regard to the transmitted signal; this time is used to compute the distance of the interface knowing the velocity of sound in medium. An experiment was set up to measure the depth of water in a container using ultrasound technique. A-mode (amplitude-mode) scanning was used where a pulsed ultrasound wave is directed into the interrogation region and echoes generated at various interfaces are detected. It is observed that levels as low as 0.55 mm were measured.© 2005 ASME


The paper by Balakrishnan et al. on intravaginal sling plasty (IVS) tape rejection can be explained by use of incorrect surgical technique. Furthermore, it describes a classic foreign body reaction, not infection. The very title of this paper summarises its lack of scientific integrity. 'Sling distress' is hardly a scientific description. The authors report a longer-term erosion rate for the IVS of 13%, the same as the short-term erosion rate for the suprapubic arc (SPARC), yet they have chosen to perform a subanalysis on one tape only, the IVS tape. No mention is made of the SPARC and tension-free vaginal tape (TVT). Balakrishnan et al. then state, 'It was already reported that the incorrect placement of the tapes was the reason for tape erosion in the SPARC group during the SUSPEND trial'. The authors do not countenance incorrect technique as a cause of the high erosion rate for the IVS tape. Yet this was proven definitively in a randomised controlled trial (n = 98) by Sivaslioglu et al., who demonstrated that using a TVT-type technique without fascial tightening resulted in a 13.6% erosion rate for the IVS tape at four years, as against a 1.8% using the recommended technique, setting the tape firmly against the urethra, and covering the tape with a layer of fascia. Then they state 'The reason for erosion among the IVS group is most likely to be one of poor incorporation of the mesh leading to tape infection'. The authors present no bacteriological evidence for infection (required) and no clinical proof of two episodes of pyrexia > 38 degrees (required). What the authors have given is a classical description of inflammation caused by a foreign body reaction, yellow vaginal discharge, usually painless. It is certainly benign. The 'foul-smelling discharge' is caused by adherence and decomposition of desquamated vaginal cells on the tape. These respond very well to vinegar douches if the decision is taken to treat conservatively. The authors do not seem to understand that there are two types of inflammation, infection and foreign body reaction. The latter shows characteristic giant cells on histology, the former, microabscesses and often, areas of necrosis. None of the references in the table present bacteriological or clinical evidence of infection. Rather, like Balakrishnan et al. the descriptions are all consistent with foreign body reaction. The authors do not seem to understand that longer term erosions occur with all implants. An implant is, after all, a foreign body. Ward et al. reported an additional three tape erosions at five years review for the TVT (n = 79). An erosion is a small price to pay for all the advantages of the 'tension-free' midurethral sling technique. Like a splinter, an erosion is essentially harmless, and at least with the IVS, can be dealt with as an office procedure. Finally, a small but important error. The statement 'The first reported use of IVS tapes in treatment of urinary stress incontinence was in 1995' is incorrect. I, myself, reported usage of the intravaginal slingplasty in 1994. Petros first used the 'intravaginal slingplasty' ('tension-free tape') technique in 1986 at Royal Perth Hospital.


Mustard greens ( Brassica rapa var. Parachinensis ) are known vegetables among consumers and have high economic value. Besides being used as a vegetable, mustard greens are also used for the treatment of various diseases so that they are included in the vegetable group which has an important role in meeting the needs of food, nutrition and medicine for the community. To increase the growth and production of green mustard plants, it is necessary to apply liquid bio-organic fertilizers that are sourced from organic materials with good nutrients needed by plants, one of which is water hyacinth weed. To improve the quality of water hyacinth liquid bio-organic fertilizer, it can be applied with the bio-activator Trichoderma sp which functions to produce liquid bio-organic fertilizer with high nutrients for plant growth and production. The purpose of this study was to determine the growth of mustard greens including plant height, number of leaves and leaf width and to test the production of mustard greens including caratenoids and vitamin C content. This study used a completely randomized design (CRD) with a single factor, namely fertilizer. Liquid organic (POC) water hyacinth fermented using Trichoderma sp. which consists of 5 levels of fertilization doses, namely A (0 ml / L), B (8 ml / L), C (16 ml / L), D (24 ml/L) and E (32 ml/L) with 5 repetitions. Based on the results of analysis of variance, it showed that the dosage treatment of water hyacinth bio-organic fertilizer with the bio-activator Trichoderma sp had a significant effect on p <0.05 on plant height, leaf width and the number of green mustard leaves at 4 weeks of age 21 day after planting. with the results of the chemical content test which showed that treatment E (32 ml/L) contained Karetenoid (0,2596 mg/100g of material) and vitamin C (0.2784 mg/100 g of material). The best dose based on the results of the study was treatment E (32 ml/L) which had a higher average plant height, leaf width and number of leaves compared to other treatments and had high vitamin A and vitamin C content. To increase the growth and production of mustard greens and other horticultural cultivation processes, it is advisable to use liquid bio-organic fertilizer for water hyacinth with the bio-activator Thricoderma sp as an alternative to natural, environmentally friendly liquid organic fertilizer.


Internal tandem duplications (ITD) of the FMS-like tyrosine kinase 3 (FLT3) frequently co-exist with inactivating DNMT3A mutations and predict poor prognosis in acute myeloid leukemia (AML). In vitro studies implicated the docking protein Grb2-associated binder 2 (GAB2) as FLT3-ITD effector. By utilizing a Flt3-ITD knock-in, Dnmt3a haploinsufficient mouse model, we demonstrate that Gab2 is essential for the development of Flt3-ITD driven AML in vivo, as Gab2 deficient mice survived significantly longer, had reduced blast counts and exhibited an attenuated spleen and liver pathology as compared to their Gab2-proficient littermates. Further, leukemic bone marrow isolated from Gab2 deficient mice displayed a reduced colony forming unit capacity and an increased sensitivity towards the Flt3 inhibitor quizartinib. Using RNA sequencing, we identify the genes encoding for Axl and the Ret co-receptor Gfra2 as targets of the Flt3-ITD/Gab2/Stat5 axis. We propose a pathomechanism in which Gab2 increases signaling of these receptors as it induces their expression and additionally serves as a downstream effector. Consequently, Gab2 promotes AML aggressiveness as well as drug resistance by incorporating the receptor tyrosine kinases Axl and Ret into the Flt3-ITD signaling network. Therefore, our data identify GAB2 as a promising biomarker as well as a therapeutic target in human AML.
 Citation Format: Corinna Spohr, Teresa Poggio, Geoffroy Andrieux, Katharina Schönberger, Nina Cabezas-Wallscheid, Melanie Börries, Sebastian Halbach, Anna L. Illert, Tilman Brummer. Gab2 deficiency protects against Flt3-ITD driven acute myeloid leukemia in vivo [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 945.


PurposeThe study examines the psychometric properties of internal communication satisfaction questionnaire (ICSQ), an instrument originally developed in Croatian. A need for a contemporary instrument validated among a non-English-speaking population of employees who use English as their second language motivated the authors to translate the scale.Design/methodology/approachICSQ was validated on a sample of 507 employees of a large Croatian subsidiary of a multinational bank, where English is the official corporate language.FindingsICSQ displayed satisfactory levels of psychometric properties, retaining the psychometric properties of the original version of the instrument. A confirmatory factor analysis revealed the acceptable model–data fit of the eight-factor model. Additionally, findings supported the reliability and construct validity of the English version of the instrument. Good internal consistencies of all eight internal communication satisfaction (ICS) dimensions and the total ICSQ and an adequate level of scale homogeneity according to the inter-item and inter-total correlations were found.Research limitations/implicationsIn order to generalize the study's results to other business areas and industries, the study should be replicated in other contexts. Additionally, construct validity was tested by applying cross-sectional design, and therefore, no conclusion can be drawn on the causal direction of the relationship. Finally, the discriminant validity of ICSQ was not tested and should be examined in future studies.Practical implicationsThe resulting 32-item instrument, in English, can be used for empirical and practical purposes in improving internal communication.Originality/valueThe study confirms that internal communication is a multidimensional construct and should be measured as such.


The Meat Standards Australia beef-grading model applies a variable adjustment for different cuts of hormonal growth promotant (HGP)-treated carcasses, but does not differentiate between different HGP types. Using 300 non-implanted Bos indicus–Bos taurus composite steers, an experiment was conducted to compare the effects of an oestradiol only (OES) and a combination trenbolone acetate and oestradiol (TBA+OES) implant with non-implanted animals (CON) fed a concentrate ration for 73 days before slaughter, on eating quality of the mm. longissimus lumborum (LL) and gluteus medius (GM) muscles. Sensory and objective LL and GM samples were aged for either 5 or 35 days before freezing at −20°C. Carcass weights from each group were significantly (P < 0.05) different. Corrected for carcass weight, HGP treatment had a significant effect on hump height, ossification score, marble score, P8 fat depth and eye-muscle area. The TBA+OES treatment resulted in significantly (P < 0.05) tougher meat than the OES and CON treatments as assessed by shear force, although this difference was reduced with aging. Sensory scores (tenderness, juiciness, like flavour, overall liking and a composite MQ4 score) confirmed a negative HGP treatment effect, whereby TBA+OES was significantly lower than the CON and OES treatments after 5 days of aging, and these differences were reduced through aging. TBA+OES had a greater impact on sensory scores in the LL when compared to the GM. Both HGP treatments increased calpastatin activity, and the TBA+OES treatment was significantly (P < 0.05) different from the CON and OES treatments. It was concluded that OES and TBA+OES implants have different impacts on meat eating-quality measurements, which could have important implications for the Australian and international beef industry.


High latitude flying in modern high-speed aircraft is hampered by lack of navigation facilities, and also by long periods of twilight during which no astro navigation is possible. Standard methods of twilight computation are applicable, but in practice have been cumbersome for the special purpose required. A simple computer is described, by means of which twilight conditions on any proposed flight can be found. Its further application to other problems is described as well. In addition a simple and improved planisphere for high latitudes is included.


The present invention relates to a micro pump injecting drugs by magnetic field having a specific frequency as a drug storage part, a driving part, and a micro channel are included, and a wireless drug delivery device including the same. The present invention is safe from outside noise and does not require an electric circuit device or current supply to the inside of a transplanting chip because heating characteristics are determined by frequency, intensity, and proximity of the magnetic field by a wireless induction heating method not an RF method, which is an electric power delivering method. The drug delivery device of the present invention can be manufactured in a thin film shape because intricate wiring is not needed in the driving part, and only a metal thin layer for induction heating is embedded. A microchip of the present invention can quickly deliver drugs in emergency situations by putting the drugs for emergency which is customized for a patient and using portable magnetic field equipment from the outside.


Abstract Transparent yttrium aluminium garnet (YAG) polycrystal can be used as a host material for a solid state laser. In the present study, the authors prepared completely transparent YAG ceramics from active powder. The optical and mechanical properties of YAG ceramics are very sensitive to point defects. In order to examine the relationship between these properties and point defects, it is first necessary to characterise the defects. The authors report the effect of doping on oxygen diffusivity in several YAG ceramics, doped with various elements. Although Nd doping slightly increases the oxygen diffusion coefficient and the number of oxygen vacancies increases with increasing Nd concentration in as sintered materials, the variation of the oxygen diffusion coefficient in well annealed samples is small. These results suggest that the oxygen vacancies exist in non-equilibrium. However, grain boundary diffusivity was not influenced by preannealing before the oxygen diffusion experiments. The oxygen defect structure in transparent YAG ceramics is also discussed.


The paper presents the issue of identification of calibration numerical model and computer program, which enables calculate thermodynamic parameters of the working charge in the engine cylinder, taking into account partial cylinder filling of working charge containing considerable quantity of exhaust gases origin from exhaust gas recirculation of actual cycle.


multiplying tubercle bacilli, it must be employedas early as possible after the patient has been infected, and particularly when the diseaseis in an acutestage. Finally, this treatmentmust be given for long enough to achieve one of the prime purposesfor which it is given-namely, eradication of all tubercle bacilli. Whenever it appears that any particular regime of treatmentis not achieving its purpose,then it must be changed.


The total sown area of winter triticale in 2020 in Belarus amounted to 456 thousand hectares. New varieties carry new qualities that need to be studied and compared in specific soil and climatic conditions, to evaluate them in order to make a decision on the possibility of their zoning or culling. The evaluation of varieties was carried out at the SAI "Goretskaya Variety Testing Station" of the Mogilev Region of the Republic of Belarus. The studies were carried out according to generally accepted methods of laying and conducting experiments. Agricultural technology of winter triticale recommended by modern technological regulations for the north-eastern part of Belarus. In total, in 2018–2020, 16 varieties of winter triticale were in variety testing. Average for 2019–2021 Compared to the control variety Dynamo, the variety IZS-3 showed itself better in terms of grain yield (+7.2 c/ha). On average, over the two years above, the yield was higher in the varieties Tadeus (+5.2 c/ha), IZS-5 (+7.0 c/ha), Tribonus (+6.0 c/ha) and Tikhon (+17.2 q/ha). According to the results of one year of testing, the yield of the control variety was higher in varieties IZS-6, IZS-7, Belkanto, Riparo and Rivolt. On the basis of competitive variety testing and assessment of ecological adaptability, it is possible to recommend the IZS-3 variety (Belarus) for inclusion in the State Register of varieties of the Republic of Belarus for cultivation in the conditions of the north-eastern part of Belarus. The varieties Tadeus (Germany), IZS-5 (Belarus), Tikhon (Russia) and Tribonus (Austria) should be recognized as promising. For further variety testing, varieties IZS-6 and IZS-7 (Belarus), Belcanto (Poland), Riparo (France) and Rivolt (France) should be recommended. Keywords: WINTER TRITICALE, VARIETY, COMPETITIVE VARIETY TESTING, YIELD STRUCTURE, PRODUCTIVITY, ECOLOGICAL ADAPTABILITY


Politicians are skilled language users who deploy words strategically and pay close attention to the emotions that those words evoke. We examined the emotional characteristics of over 92 million words spoken by Canadian Members of Parliament between 2006 and 2021. The analysis brought together the Warriner, Kuperman, and Brysbaert (Behav. Res., 2013, 45, 1191–1207) database of valence (positivity) ratings for English and the Canadian Hansard, which contains a transcription of parliamentary speech. Results revealed that the positivity of words used by politicians in parliament was significantly related to both political and social variables. Politicians increased the positivity of their language after the onset of the COVID-19 crisis. Within the time of the crisis, word positivity was linked statistically to month-by-month case counts, indicating a very fine-grained sensitivity to social realities. Our analysis also revealed a fine-grained sensitivity of word valence to political realities. As expected, parties in power used more positive language than those in opposition. In addition, our analysis revealed that individual parties have characteristic levels of word positivity and that those levels change in accordance with political changes as specific as whether or not the party in power holds a majority of seats in parliament. These findings suggest that the emotional properties of words used by Members of Parliament are reliably indexed to sociopolitical dynamics. The findings also suggest that the methodology of linking individual word ratings to Hansard Documents (which are used to document Parliamentary activities in over 25 countries) can provide a key tool for the understanding of specific crises such as the COVID-19 global pandemic as well as more general social and political trends across countries and languages.


To investigate the relation between apoptosis of intrahepatic cholangiocarcinoma cell lines 9810 and expression of bcl-2 gene. We detect its apoptosis and expression of bcl-2 gene by flow cytometer. Apoptosis of intrahepatic cholangiocarcinoma was up step by step flowing Adriacin's concentration, expression of bcl-2 gene was down as well as it. Influencing expression of bcl-2 gene may be a reason of apoptosis of intrahepatic cholangiocarcinoma cell.


In this paper we consider the digital space Z with Khalimsky topology and Zn with corresponding product topology. We study some properties of continuous functions from Zn into Z and prove some related results.


The principles of space vector PWM(SVPWM)for neutral-point-clamped(NPC)three-level inverter was introduced.Proposed the algorithm of space vector PWM for three-level inverter,which is practical easy to realize.This algorithm inherits primely the idea from two-level SVPWM which was applied extensively.The balancing control scheme of capacitor neutral point voltage was presented based on the proposed SVPWM algorithm by adjusting switching point of space vectors.Realization of three-level SVPWM based on one digital signal processor TMS320F2407 was proposed.In the realization,plotting the pin and configuring the registers properly in DSP are necessary.The simulation and experiment results verify that the proposed vector PWM algorithm and realizing method are valid and feasible.


This paper reviews recent investigations of the influence of dopants on the optical properties of TiO2 polymorphs. The common undoped polymorphs of TiO2 are discussed and compared. The results of recent doping efforts are tabulated, and discussed in the context of doping by elements of the same chemical group. Dopant effects on the band gap and photocatalytic activity are interpreted with reference to a simple qualitative picture of the TiO2 electronic structure, which is supported with first-principles calculations.


The central task of modern colleges is to produce the excellent graduates. Therefore, teaching should be the key moment. The content and mode of training programmes must be reformed, for they are faced with serious challenges. In the reform to come, the change of classes and texts should be the core, the construction of the teachig staff should be the key, and the transformation of educational ideas should be the first step.


The Fundamental Rights Agency of the European Union (FRA) is the European Union's newest, and only, human rights institution. The FRA represents a new way of speaking about rights in the European Union, using 'governance' language. It was not conceived as a traditional human rights monitoring body and the monitoring mission was actively abandoned in favour of an advisory one. This article examines how the FRA's governance-related role actually reveals a type of monitoring best understood as 'surveillance' in a critical, Foucauldian sense. In exercising surveillance tactics, the FRA represents a model of panopticism which allows it to carry out a new form of government. This is an interesting observation not only because of the implications it has for a European Union that is striving to move away from government towards governance, but also because it challenges the assumption of the FRA as a 'beacon on fundamental rights' and a model of apolitical progress.


Reverse micelles are complex systems consisted of water, hydrocarbon and surfactant. In spite of large content of water (up to 90 mol%) the electric conductivity and electric permittivity is relatively low, sound velocity is practically the same as for pure hydrocarbon. The reason for these "mysterious" properties is the structure of reverse micelles -water is hidden in surfactant shell and surrounded by nonpolar solvent. Change in volume fraction of micelles leads to an interesting phenomenon linked with percolation. In the contribution we would like to present our recent results obtained in docusate sodium salt + water + isooctane mixture. The most interesting and actually not fully understood phenomenon is an enormous positive non-linear dielectric effect observed in the aforementioned system.


A photomicrographic method for the measurement of air-borne droplets is described. The droplets are photographed naturally suspended in air. Axial illumination is provided by a repetitive light source of high intensity. nark field illumination is used to permit multiple exposures on a single negative. A magnification of 250 times on the negative is obtained by a microscope objective and ocular mounted in a tube attached to the camera. Droplets as small as 2 μ in diameter may be measured directly from the negative, from prints made of the negative, or by projection on a screen. The size of droplets determined by means of the camera were demonstrated to compare in accuracy with measurements made by common microscope techniques. The droplets used for comparison were of uniform size and were produced by a mechanical generator, the construction and operation of which is described.


The invention discloses a pressure-controllable high-precision fine-tuning clamp which belongs to the field of clamps. The clamp comprises a clamp base, a left fixing block, a left screw rod, a left clamping block, a right clamping block, a guide rod, a right fixing block as well as a driven connecting rod, a left spring, a driving connecting rod, a right spring, a transmission rod, a right screw rod, a handle and a scale disc, wherein one end of the driven connecting rod is hinged to the clamp base; the other end of the driven connecting rod is connected with the driving connecting rod through the transmission rod; one end of the driven connecting rod close to a chain is connected with the guide rod; the scale disc is arranged on the handle. The clamp solves the problems that a conventional clamp cannot be turned finely, the clamping force is difficult to control and the positioning precision is not high, and has the advantages of simple structure, reasonable design and easiness in manufacturing.


Let p, q be distinct primes with gcd(p 1, q 1) = 4. In this paper, we calculate the autocorrelation values of binary sequences of generalized cyclotomic sets of order four in


This document describes a simple and efficient mechanism to perform L2
or L3 VN Context validation and to detect any data plane failures in
IPv4 or IPv6 based overlay network providing L2 or L3 virtualized
network.


This article is not purported to present an exhaustive analysis on the subject of Alternative Dispute Resolution in the UK and other commonwealth countries. It is rather a practical guide which provides a general outline on the subject matter, paying particular attention to the process, pros and cons as well as some significant case law and legislation. In effect it enables the reader to build a 'solid foundation' on ADR fast, and then enhance this knowledge.


Jose I. Barraquer theorized that because the cornea accounts for two-thirds of the refractive power of the eye, a change in its curvature could have a great effect on the refractive error. Subsequently, researchers have developed several refractive procedures in the cornea for this purpose. The corrections of the spherical refractive errors, such as myopia and hyperopia, have progressed much more efficiently than has the correction of astigmatism. Patients with astigmatism cannot accommodate or "correct" for it as do patients with hyperopia and, besides sparing defocus, they may complain of ghost images or even diplopia. This is why astigmatism must be properly diagnosed and also corrected. Corneal astigmatism may be regular or irregular. In the astigmatic eye, the refractive power is not the same in all meridians: When it is regular, the maximal and minimal powers of the eye are 90 degrees apart, or orthogonal, and when corneal, topography is uniformly nonspherical, usually designated as a toric surface. Conversely, irregular astigmatism occurs when the power changes irregularly along the meridians, and when it is corneal as usual, it is clearly seen with the topographical map. Irregular astigmatism can occur as a result of trauma, keratoconus, corneal disease, corneal infection and others. Sometimes it is the result of surgical procedures, such as pterigyum removal, penetrating keratoplasty (PK), and cataract extraction. In fact, there are numerous descriptions of irregular astigmatism as a complication of several refractive procedures, such as photoablative techniques with the excimer laser. Although there are several ethiologies, some of the most common have been central islands, a small optical zone, and decentrations.


The purpose of this study is to increase understanding of how a knowledge- intensive company designs its belief system in the start-up. The study also aims to investigate in what way the company va ...


Moon Diver is a proposed mission to land and deploy an extreme-terrain, tethered rover for the exploration of Tran-quillitatis Pit, a large vertical cave entrance into the subsurface of Earth's Moon. By leveraging a supportive tether, the Axel rover, developed by NASA's Jet Propulsion Laboratory, would perform a controlled descent into the pit and deploy instruments along the pit wall. The purpose of this mission concept is to study a volcanic secondary crust as a function of depth in order to determine formation processes and chemical makeup. The lifeline of the mission would be the tether, which provides power from, and communication to the top-side lander. Critically, the tether also serves as mechanical support between the suspended rover and the lander, which acts as an anchor. While space tethers have been deployed both in orbit and terrestrially, the use of the proposed tether is unlike any known in the literature; the tether must come into contact with the terrain while under load. With respect to the environment, the tether must also survive abrasion from glassy regolith and volcanic rocks, bending around sharp edges, thermal extremes, and exposure to full spectrum ultra-violet (UV) radiation, all while reliably transferring up to 100 W of power and 1 Mbps of data. Furthermore, since the Axel rover pays out tether from an internal spool, the tether's diameter must be minimized to increase spool capacity, allowing for up to a 300-m traverse while also meeting static and dynamic strength requirements. This paper covers several phases of the tether's initial development, including i) a trade study of structure and materials with consideration for space heritage, ii) selected design justification, and iii) results from tests on prototype tethers looking into mechanical, electrical, and environmental properties, including exposure to rock-regolith abrasion, load profiles at temperature, and degradation due to UV exposure while exposed to vacuum. Finally, we provide insights and lessons learned from lab and field tests, which inform our continued effort to design a tether capable of surviving rugged, lunar conditions.


A large amount of electrical power harmonic are injected into the electrical power network because the widely used of nonlinear electrical power load. It brings a great harm to the precision electronic instrument in safety running. This article presented a kind of electrical network harmonic analysis algorithm used for the harmonic signal separation. Through analyzing the harmonic monitor technology at present, using the blind signal separation technology to complete the mixing electrical power system voltage signal separation based on the traditional information maximization blind source separation algorithm and natural gradient algorithm, the simulation result shown that this two algorithm can also realize the instantaneous mixing voltage harmonic signal separation and harmonic analysis monitor. The result expressed that this method can effectively gain a good separation effect with the monitoring spectrum error is less than 1 %. Copyright © 2013 IFSA.


In 2010, the author participated in an assessment of the coal deposits on Encana Corporation's freehold lands in Alberta, Canada. He suggested that coal samples collected from a well in the Alberta...


We consider an anisotropic variant of the light switching game of Gale and Berlekamp. For $m\geq2$, we begin with a matrix $\left( a_{j_{1} \ldots j_{m}}\right)_{j_{1},\ldots,j_{m}=1}^{n_{1},\ldots,n_{m}}$ whose elements are unit vectors in the Euclidean space $\mathbb{R}^{2}.$ The initial direction pattern of each $n_{1}\cdots n_{m}$ vectors is set up at the beginning of the game. For each $k\in\{1,\ldots,m\}$, we have $n_{k}$ knobs $x_{1}^{(k)},\ldots,x_{n_{k}}^{(k)}$; when the knob $x_{j_{k}}^{(k)}$ is rotated by an angle $\theta_{j_{k}}^{(k)}$, the same happens with all the vectors $a_{j_{1} \ldots j_{m}}$ with $j_{k}$ fixed. For an initial pattern of unit vectors $\Theta$, let $s(\Theta)$ be equal the supremum of the (Euclidean) norm of the sum of all $n_{1}\cdots n_{m}$ vectors achievable by adjusts along the $n_{1}+\cdots+n_{m}$ knobs starting with the pattern $\Theta$; the game consists in determining the value of \[ \min\{s(\Theta):\Theta\text{ an }n_{1}\times\cdots\times n_{m}\text{ pattern}\}. \] We show that \[ (0.886)^{m-1} \leq \frac{\min\{s(\Theta) : \Theta \text{ an } n_{1} \times \cdots\times n_{m}\text{ pattern} \}} {\sqrt{n_{1\cdots}n_{m}}\max\{\sqrt{n_{1}}, \ldots, \sqrt{n_{m}}\}} \leq1. \]


The analysis and discussion of randomness of periodic components of helicopter vibration and missne launch induced vibration are presented. For analyzing the randomness of periodiC components, a sinusoid-random separation technique in the frequency domain is adopted. Statistical analysis of the periodic components separated from the helicopter vibration exposes that under steady flight conditions, the components are determinsitic, and these random fluctuations are due to the noise of measurement and analysis, whereas under unsteady flight conditions, the components are normally distributed random variables due to random fluctuations of flow field and a considerable change of rotor controls. Fot the nonstationary random vibration induced from missile tallnch, it is found that the take-varying statistical parameters of the vibration can be obtained by use of mathematical modening and filtering technique, and a quantitatiye equation of the effectiveness of a vibration isolator can be made by energy spectrum antois.


In this study; in order to diagnose congestive heart failure (CHF) patients, non-linear second-order difference plot (SODP) obtained from raw 256 Hz sampled frequency and windowed record with different time of ECG records are used. All of the data rows are labelled with their belongings to classify much more realistically. SODPs are divided into different radius of quadrant regions and numbers of the points fall in the quadrants are computed in order to extract feature vectors. Fisher's linear discriminant, Naive Bayes, Radial basis function, and artificial neural network are used as classifier. The results are considered in two step validation methods as general k-fold cross-validation and patient based cross-validation. As a result, it is shown that using neural network classifier with features obtained from SODP, the constructed system could distinguish normal and CHF patients with 100% accuracy rate.


The research on the removal of sulfates from mine wastewater is presented in the article. A new purification method has been proposed that allows removing a significant part of sulfates by precipitation in the form of barium sulfate. The present studies were devoted to the removal of sulfates from mine wastewater with a sulfate content of 1050 mg/l by introducing various doses of barium-containing reagents, namely barium chloride, hydroxide and barium carbonate. Among the listed reagents, the best results were obtained, using barium chloride and hydroxide. The use of barium chloride with a dose of 2700 mg/l and barium hydroxide with a dose of 3200 mg/l made it possible to reduce the concentration of sulfates below the maximum permissible (100 mg/l) when discharged into a reservoir for fishery purposes. A reliable in operation technological scheme for removing sulfates from highly concentrated mine wastewater has been developed, which makes it possible to reduce sulfates in the treated waste liquid discharged into the reservoir to 100 mg/l and below. In this case, the purification is carried out with separation of streams - in a smaller part (about 26% of the incoming); barium chloride is introduced, in the second - barium hydroxide. After that, the streams are mixed again, settled, sent to the calciner and to the post-treatment facilities and discharged into the reservoir. The resulting sludge is stored in special landfills or is processed to extract valuable components.


Common types of electrical contact materials are considered. Nickel-based coatings with non-metallic additives (bo-ron, phosphorus) as electrical contact materials are proposed. The electrical and mechanical properties of nickel-based coatings were studied for various methods of their formation. An increase in the transition resistance and a de-crease in the electrical erosion of coatings with an increase in the concentration of non-metal for crystalline and amorphous-crystalline structures have been shown. The influence of the passive Au – Co film on the mechanical and electrical properties of the coatings has been considered.