Identify the diseases in Tobacco plant by using digital image processing techniques as well as deep learning model. So we introduce image processing and deep learning technique to determine fungal and virus infection in Gloriosa Superba diseases at initial stage. Initially, the source images are collected from several Tobacco cultivation areas in Tamilnadu using a digital camera. In this dataset collection, we have collected totally 150 images, in these images are not enough for proper training and testing purposes for deep learning classifiers, so we applied data augmentation, which can increase the dataset size, also prevent overfitting and improve the classification accuracy. Initially, we pre-process the input images using the median filter and segmentation using the U-Net based segmentation technique. And also extract the features from input image by using Color-Related Feature Extraction system. Finally, classify the images as diseases affected or healthy as classify by using Deep Convolution Generative Adversarial Network (DCGAN). In this proposed model, experimentation is conducted using the python OpenCV model, and the performance is evaluated using different performance measures, which is designated in the result section. In the proposed scheme achieved the better classification performance of 97.94% respectively


This position paper is an overview of the journal article [1] where we propose HANA, a software architecture for agents to sign agreements about joint plans of action in a multiagent system (MAS) with repeated interactions. Negotiations are bilateral and may involve humans. We assume that there are specific time deadlines for action execution and that the agents have to negotiate while exploring what set of actions to perform. Realistic problems involving humans use to be of the incomplete information type and have a huge space of solutions. That means that the space is large enough and the negotiation time short enough to preclude looking for the optimal solution. That means that any architecture for this type of negotiation problem needs to give the means to look for good-enough solutions.


A finite set of points, S, in a projective or affine space such that no lines intersects S in exactly two points is known as a Sylvester-Gallai (SG) configuration. In real space it is well known that there are no nonlinear SG's. There are several simple proofs of this fact (see [1]-[4]) and we offer here still another, as far as we know somewhat different from the others. The result in E' follows from that in E2 by projection.


The most common role of traffic lights are as signal systems to control transportation at urban networks and traffic management. Urban traffic lights in most of countries used fixed time. The traffic light systems installed on urban traffic network at an intersection consist of four arms. There is a railroad crossing on the south arm. At this time introduced the new model design of interruptive traffic lights. The new model is the syncronization between traffic lights and train doorstop. It is modeled by Petri Net. The method to analyze the model using: 1. Invariant Method. 2. Occurrence Graph Method, and 3. Simulation. The queue of vehicles happens at extension schedule less than queue at regular schedule if the closure of the railway doorstop ended when the lights north-south traffic lights red. Probability of north-south traffic light flashed red in a cycle is 0.62. The statistical expectation value of the number of queues of vehicles on extension schedule decreased. On south arm down 2.71 PCU and on northern arm down 2.34 PCU. It means that extension schedule gives positive results. The extra green 16 seconds will improve the performance of traffic light.


3627 Background: Although complete (R0) resection of liver metastases (LM) remains the treatment of choice for colorectal cancer (CRC) patients amenable to curative therapy, only about one-third su...


n optical signal transmission, binary signals are encodedin pulses of light traveling along optical fibers. An unde-sirable consequence is that if somebody taps into the system andsplits off a small portion of the light pulse, he has complete accessto the signal while remaining virtually unobservable.


A re-usable component-based framework is proposed for modeling and simulation of multi-agent supply chain systems. The framework facilitates study of both intraas well as interorganizational issues simultaneously across a supply chain (SC) paying due attention to the issue of private as well as public information. It utilizes a pre-developed library of organizational primitives, supply chain primitives, agent behaviours, and policy objects in order to configure a SC of interest. The framework architecture integrates several software tools and technologies for implementing the framework. It utilizes Java and Java Agent DEvelopment Framework (JADE) for implementing various agent components, behaviours, and policy objects, Protege and Beangenerator for SC domain ontology development, PostgreSQL for database back-end support, Apache Ant for Java code compilation, and Eclipse as an Integrated Development Environment (IDE) for facilitating integration and development. With the help of the libraries developed the user can quickly put together a multi-agent system (MAS) for a given supply chain and perform simulation and study coordination issues. The utility of the proposed framework is demonstrated through multi-agent simulation of Tamagotchi SC. The results of the study are presented and some of the research extensions being pursued are discussed.


Carbon tetrachloride and its toxic metabolites consistently produce liver injury in many species including man. The hepatoprotective potential of Chromolaena odorata Linn. (C. odorata) was evaluated in male rabbits against carbon tetrachloride-induced liver damage. Carbon tetrachloride intoxicated control (CCl4) and ethanol extract of C. odoratatreated rabbits (ETECO TEST) received a single dose of CCl4 (0.2 ml/kg bw in liquid paraffin 1:1). Pre-treated rabbits received ethanol extract of C. odorata at 400 mg/kg/day in two divided doses of 200 mg/kg in morning and at night for 6 days prior to CCl4 administration. Sylimarin control received 50 mg/kg bw as a replacement for ETECO prior to CCl4 intoxication. Normal animals received only extract in the above stated dose and served as extract controls (ETECO CTRL). Pre-treatment with C. odorata significantly (p<0.05) prevented the elevation of serum aspartate aminotransferase (AST), alanineaminotransferase (ALT), lactate dehydrogenase (LDH), gamma glutamyl transferase (ץ-GT), total bilirubin and malondialdehyde (MDA) resulting from carbon tetrachloride intoxication. C. odorata extract also significantly (p<0.05) prevented a decrease in serum total protein, albumin, and glutathione (GSH) concentrations. The extract also significantly (p<0.05) prevented a decrease in superoxide dismutase (SOD), catalase (CAT) and glutathione-s-transferase (GST) activities. The presence of secondary plant metabolites like alkaloids, saponins,


The present study has been carried out to clarify the influence of H2O2 on photophysical behavior of a manganese porphyrin, namely: Mn(III)-5,10,15,20-tetra(4-methylphenyl)porphyrin chloride (MnTTPCl) and to reveal if this metalloporphyrin is suitable for usage as sensitive material in O2 gas detection. Upon increasing the concentration of the H2O2 solution, the decrease of the absorption intensity of the Soret (V) band was noticed as a linear function with a good correlation coefficient. The capacity of the manganese porphyrin to generate aggregates was investigated by AFM in different solvents (THF and CHCl3) before and after H2O2 introduction. In THF the AFM images of bare Mn-porphyrin displayed small triangular particles and platelets that are characteristic of H aggregates. These aggregates became larger but of the same shape after H2O2 interference. On the other side, CHCl3 favored micro-structured ring shapes, obtained by the subsequent side by side J-process of H-types architectures, these circular geometries coexisting together with triangular or straw like structures.


Summary
This paper reviews what is currently known about the behaviour of the t-statistic when one is no longer sampling from a normal distribution. Suppose Y is a batch of data on which the t-test is performed. Briefly then, heavy-tailed components of Y give a light-tailed t, positive correlation among Y gives a heavy-tailed t, and positively skewed components of Y give a negatively skewed t. The emphasis is on understanding why one gets this type of behaviour, although some numerical tables are presented to illustrate the conclusions.


One small event in 18th-century India has proved an enduring myth, and an enduring puzzle. In 1756, the Nawab of Bengal besieged the British East India Company's fort at Calcutta, and 146 people were locked in a tiny cell. The following morning, only 23 emerged: all the rest had died horribly of suffocation or thirst. That is the version enshrined in the history books for centuries. But was it true? What really happened in the Black Hole is shrouded by layers of self-interest, emotion and propaganda. Its real power is as a symbol. Jan Dalley takes us through a rattling history of the buccaneer 'hatmen' of the East India Company, tracing the growth of the fledgling city of Calcutta. She brilliantly, and with fabulous and pointed detail, describes the places and the people of this amazing story, whether it is the Eurasian teenage bride Mary Carey, the lone woman survivor, the weak English officer class running the Fort of Calcutta, or the imperious, truculent Nawab of Bengal, Siraj-ud-daulah. The way in which the narrative was told and re-told, and how it became one of those stories around which nations form an idea of themselves, is the focus of this book. "The Black Hole" will fascinate everyone interested in India, in British history and in a new look at Empire.


Objective To investigate the effect of early fluid resuscitation on the prognosis of SAP patients.Methods Patients who were admitted to our hospital within 72 h after the onset of the SAP were enrolled.The parameters for the fluid resuscitation were as follow: heart rate <120 beat/h,urine output ≥ 1 ml ·h-1 · kg-1,hematocrit ≤35% and mean arterial pressure 65 ~ 85 mmHg ( 1 mmHg =0.133 kPa).The effects of different time of reaching fluid resuscitation ( <48 h,48 -72 h,>72 h) and parameters achieved (0 ~ 1parameter,2 parameters,3 parameters,4 parameters) on the prognosis were analyzed.Results There were 70 patient enrolled in this study and 41 ( 58.6% ) developed complications,20 ( 28.6% ) were referred to surgical operation and 10( 14.3% ) died.The median hospital stay was 23.5 d,and the median medical cost was 71.9(5.7~567.4 thousands RMB).The rates of surgical intervention in <48 h,48 ~72 h,>72 h groups were 20.0%,33.3%,75.0%,and the rates of acute kidney injury were 20.0%,25.0%,75.0%,while the rates of complications were 50.0%,83.3%,100%,and the difference among the 3 groups was statistically significant (P < 0.05 ).The rates of surgical intervention in patients achieving 0 ~ 1,2,3,4parameters within 48h of SAP onset were 50.0%,26.3%,13.0%,25.0%,and the rates of acute kidney injury were 45.0%,31.6%,17.4%,0,while the rates of ARDS were 35.0%,31.6%,13.0%,0,which showing a significant decreasing trend.Conclusions An appropriate fluid resuscitation in the first 48 h after the onset of SAP was benefit for improving the treatment effects and patients' outcome.

Key words:
Pancreatitis, acute necrotizing;  Retrospective studies;  Fluid resuscitation


Due to significant developments over the last decades, laser beam welding has become a well-established industrial process offering high processing speeds and causing low component distortions. But an important issue currently preventing its intense use, especially in the energy or plant construction sector where high alloy steels are applied, concerns hot crack formation. Although considerable advances in understanding hot cracking mechanisms have been made, most of the known influencing factors are metallurgical in character. The thermo-mechanical effects are barely considered or quantified. Up to the present, there exist numerous hot cracking tests that were however conceived for welding methods other than laser beam welding. Considering the special features of the laser welding process, such as high cooling rates and the narrow process zone, results obtained with other welding techniques and test procedures cannot be transferred to laser beam welding. In this study, the laser beam weldability of various stainless steels was examined in terms of their susceptibility to hot cracking by means of the controlled tensile weldability test, which was proven to be suitable for use in conjunction with CO2 laser welding. This test allows the application of tensile strain at a variable fixed cross-head speed transverse to the welding direction. Full and partial penetration bead-on-plate welds were produced. In a first attempt to determine the impact of the applied external strain on the local transient strains and strain rates near the weld pool, an optical system was used to measure the backside surface of partial penetration welds. The results showed the influence of the strain and the strain rates on hot crack formation. Furthermore, a classification of the studied austenitic, duplex and ferritic stainless steels according to the established test criteria (critical strain and cross-head speed) was conducted.


This document is based on the rent-seeking theory, the relationship culture, resource dependence theory, social exchange theory and stakeholder theory, and using the empirical data of Chinese private listed corporations in 2011, from this point of view that the political connection enterprises will better fulfill their social responsibility, research the social effects and economic effects of the political association of private listed corporations. Empirical study finding, The scale of employees and level of charitable donations of private listed corporations with political association are significantly higher than that no associated corporations, and the stronger degree of political connection, its employees scale is greater and the level of charitable donations is higher; Corporate performance of private listed corporations with political association better than no Associated Corporations, and the stronger degree of political connection, the corporate performance better. This study has a profound significance on using the advantages of private Corporations' political connections to improve the long-term competitiveness of Corporations .


This paper describes how long distance travel produces a substantial part of all person kilometers and it is growing rapidly. The train's market share in Europe is small and ever decreasing. Two studies analyze train attractiveness in international travel. The main explaining factors are number of transfers, travel time, obligation for seat reservation, and train status. Second in importance is price. Train demand is also dependent on attributes of the car alternative, while demand for high-speed services might be influenced by travel time of the airplane. Developments in European train supply are both advantageous and disadvantageous for train attractiveness.


The area is located between the foot of the San Gabriel
Mountains and the Santa Clara River and is about four miles
east of Newhall and Saugus, California. It is about thirty-six miles north of Los Angeles, California. The area is approximately two by two and a half miles in
size and contains about five square miles. It is bounded on
the north by the Santa Clara River; on the east, by the area
worked by John A. Battle; on the south, by the San Gabriel
Mountains and Placerita Canyon; and on the west, by Longitude 118 28'. The area is conveniently reached by one of two roads.
The side to the north is reached from the Palmdale-Los Angeles State Highway which runs along the northern boundary. Someday this highway will pass through the area. From this highway, dirt roads lead towards the center of the area, passing through the valleys draining into the Santa Clara River. The south side is entered by means of the Placerita Canyon Road which turns off just north of the outskirts of Newhall. This road is paved part way, but is dirt the rest of the way. It is, however, passable, and makes it easy to get into the southern end. From this road, the center of the area can be reached by hiking up abandoned roads and trails. No part of the area is more than one mile's hike to reach.


The in-cabinet response spectrum is used to define the input motion in the seismic qualification of instruments and devices mounted inside an electrical cabinet. This paper presents a procedure for generating the in-cabinet response spectrum for electrical equipment based on in-situ testing by an impact hammer. The proposed procedure includes an algorithm to build the relationship between the impact forces and the measured acceleration responses of cabinet structures by estimating the state-space model. This model is used to predict seismic responses to the equivalent earthquake forces. Three types of structural model are analyzed for numerical verification of the proposed method. A comparison of predicted and simulated response spectra shows good convergence, demonstrating the potential of the proposed method to predict the response spectra for real cabinet structures using vibration tests. The presented procedure eliminates the uncertainty associated with constructing an analytical model of the electrical cabinet, which has complex mass distribution and stiffness.


Water is an important resource especially for agricultural country like Thailand. Hydro and Agro Informatics Institute of Thailand launched a project which introduces UAVs equipped with video cameras for improvement of the efficiency in water resource survey. This paper presents the UAV system that has been developed in this project. The flight data shows the capability of accurate automatic way-point flight. Histogram-based image segmentation was applied to the aerial image for the purpose of estimation of water surface area in order to show the usefulness of the UAV system. The estimation results are evaluated and discussed.


in patients undergoing elective coronary artery bypass grafting. J Thorac Cardiovasc Surg 2004; 128: 425–31 22 Ranucci M, Baryshnikova E, Soro G, Ballotta A, De Benedetti D, Conti D. Multiple electrode whole-blood aggregometry and bleeding in cardiac surgery patients receiving thienopyridines. Ann Thorac Surg 2011; 91: 123–9 23 Vilahur G, Choi BG, Zafar MU, et al. Normalization of platelet reactivity in clopidogrel-treated subjects. J Thromb Haemost 2007; 5: 82–90 24 Zafar MU, Santos-Gallego C, Vorchheimer DA, et al. Platelet function normalization after a prasugrel loading-dose: time-dependent effect of platelet supplementation. J Thromb Haemost 2013; 11: 100–6 25 Storey RF, Bliden KP, Ecob R, et al. Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses. J Thromb Haemost 2011; 9: 1730–7 26 Prüller F, Drexler C, Archan S, Macher S, Raggam RB, Mahla E. Low platelet reactivity is recovered by transfusion of stored platelets: a healthy volunteer in vivo study. J Thromb Haemost 2011; 9: 1670–3 27 Douketis JD, Spyropoulos AC, Spencer FA, et al. Perioperative management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141: e326S–50S 28 Gogarten W, VandermeulenE, Van Aken H, et al. Regionalanaesthesia and antithrombotic agents: recommendations of the European Society of Anaesthesiology. Eur J Anaesthesiol 2010; 27: 999–1015 29 Horlocker TT. Regional anaesthesia in the patient receiving antithrombotic and antiplatelet therapy. Br J Anaesth 2011; 107(Suppl. 1): i96–106 30 Jakubowski JA, Payne CD, Weerakkody GJ, et al. Dose-dependent inhibition of human platelet aggregation by prasugrel and its interaction with aspirin in healthy subjects. J Cardiovasc Pharmacol 2007; 49: 167–73 31 Jackson SP. The growing complexity of platelet aggregation. Blood 2007; 109: 5087–95 32 Hosokawa K, Ohnishi T, Fukasawa M, et al. A microchip flowchamber system for quantitative assessment of the platelet thrombus formation process. Microvasc Res 2012; 83: 154–61 33 Hosokawa K, Ohnishi T, Sameshima H, et al. Analysing responses to aspirin and clopidogrel by measuring platelet thrombus formation underarterial flow conditions. Thromb Haemost 2013; 109: 102–11 34 Bevers EM, Comfurius P, Zwaal RF. Platelet procoagulant activity: physiological significance and mechanisms of exposure. Blood Rev 1991; 5: 146–54 35 Kozek-Langenecker SA, Afshari A, Albaladejo P, et al. Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol 2013; 30: 270–382 36 GorlingerK,Shore-LessersonL, DirkmannD,Hanke AA,Rahe-MeyerN, Tanaka KA. Management of hemorrhage in cardiothoracic surgery. J Cardiothorac Vasc Anesth 2013; 27: S20–34 37 Skolnick BE, Shenouda M, Khutoryansky NM, Pusateri AE, Gabriel D, Carr ME. Reversal of clopidogrel-induced bleeding with rFVIIa in healthy subjects: a randomized, placebo-controlled, double-blind, exploratory study. Anesth Analg 2011; 113: 703–10 38 van der Linden J, Lindvall G, Sartipy U. Aprotinin decreases postoperative bleeding and number of transfusions in patients on clopidogrel undergoing coronary artery bypass graft surgery: a double-blind, placebo-controlled, randomized clinical trial. Circulation 2005; 112: I276–80 39 Thiele T, Sumnig A, Hron G, et al. Platelet transfusion for reversal of dual antiplatelet therapy in patients requiring urgent surgery: a pilot study. J Thromb Haemost 2012; 10: 968–71


Uncertainty in estimation of Drake Passage transport is analyzed in a Hessian-based uncertainty quantification (UQ) framework. The approach extends the adjoint-based ocean state estimation method to provide formal error bounds functionality. Mechanisms of uncertainty propagation in an idealized barotropic model of the Antarctic Circumpolar Current are identified by analysis of Hessian and Jacobian derivative operators, generated via algorithmic differentiation (AD) of the MIT ocean general circulation model (MITgcm). Inverse and forward uncertainty propagation mechanisms are identified, projecting uncertainty between observation, control and state variable domains. Time resolving analysis of uncertainty propagation captures the dynamics of uncertainty evolution and reveals transient and stationary uncertainty regimes. The UQ system resolves also the dynamical coupling of uncertainty across different physical fields, as represented by the off-diagonal posterior covariance structure. The spatial patterns of posterior uncertainty reduction and their temporal evolution are explained in terms of barotropic ocean dynamics. Global uncertainty teleconnection mechanisms are associated with barotropic wave propagation. Uncertainty coupling via data assimilation is demonstrated to dominate the reduction of Drake Passage transport uncertainty, highlighting the importance of correlation between different oceanic variables on the large scale.


In the field of surveillance, several algorithms are developed to extract meaningful information from an image captured via a camera. In the presence of intrusion event, these cameras will transmit those captured images to the sink node via other intermediate nodes. Since, WSNs operate with limited resources, efficient utilization of resource is needed while processing and transporting images. Since the node does not need whole image data are mandatory. Prioritization is one of the methods to utilize the available resource. It will prioritize images from its macro-blocks dynamically. Here the camera is attached in a sensor node which forms Wireless Multimedia Sensor Networks (WMSN). Its employs an encoding scheme at the source node by naming the blocks as "important" or "not-important" based on the information they contain. Here image texture feature and spectral information is used as priority measures to weight importance of macro-blocks using their textural GLCM properties. Experimental results disclose that the priority encoding scheme adapts itself to the application's quality requirements while reducing the required bandwidth


More than 3.5 billion people use the internet today, up from a mere 738 million in 2000, according to a new report from the International Telecommunication Union (ITU). That's about half the world's population. But what about the other half? While the ITU says that most of the world's other internet-less users will be connected by traditional internet service providers (ISPs), many remote and rural regions risk remaining without access – unless they connect themselves. This digital divide exists even in developed Europe, where governments are pouring billions of euros into high-speed internet networks.

Community networks can help fill the gap. Built and operated by people from within the community working together and combining their efforts, these networks complement traditional access networks. They provide local access in areas where commercial operators do not find it economically viable to operate. Given the challenges with economic viability in underserved areas, it is crucial to build a sound business model to ensure the sustainability of these projects. Community Networks must overcome serious regulatory, political and commercial hurdles. Regulation is often inadequate – or inappropriate. Needed spectrum remains expensive or unavailable. In response, the European Commission has given its support for these bottom-up projects, recognising Community Networks as one of the four main investment models for bringing internet coverage throughout the continent

This paper looks at the challenges and opportunities involved in setting up, maintaining and expanding operations of Community Networks within the European Union and elsewhere in Europe. Based on personal interviews with officials in Brussels as well as telephone conversations with leaders of Community Networks throughout Europe, it draws lessons learned from a selection of projects ranging from Spain in the West to the Republic of Georgia in the East.


The work that the teacher does to enhance the different abilities of the students is transcendental for their development, especially when children with cognitive abilities are within the group of people with special educational needs. Therefore, the main objective of the degree work is to describe the different Dducational intervention strategies such as enrichment, acceleration and grouping. These are used by teachers to work with children in early education with cognitive abilities and exceptional talents. The present study has a qualitative approach that can be analyzed and contemplate the information during the research and the investigative study of this population, considering the objectives and the established problems. In addition, it is aimed at a type of exploratory that has already addressed issues that have not been investigated before or that sometimes have not been investigated in depth. Within the theoretical framework, the terminology between high capacity, exceptional talent, genius, prodigy and giftedness is differentiated. In addition, the legislative regulations that safeguard the right and the opportunity to education for this
population in Ecuador and in other countries were based. The strategies used for teachers in different countries were presented, and in which the processes of identification, educational intervention and curricular adaptation models are considered. The tools that were used in this investigation were the following: an important part of the educational activities one fiscomisional and another private one. Finally, with the information collected, an analysis of the results is made in which it is evident that the teachers are unaware of this issue as far as itis concerned, an educational magazine that provides information about children with exceptional talents is opened and published. , focused on teachers and
parents.


PURPOSE:To improve the memory retaining property with a charge diffusion barrier film in the second gate insulating film for charge storage provided on a gate insulating film presenting a tunnel phenomenon of the charge. CONSTITUTION:An Si4N3 film 51 is piled on an extremely thin SiO2 film 4 and immersed in a specified mixed solution of H2SO4 and H2O2 to form an extremely thin SiO2 film 42. By the same procedure, an SiO2 film 42 serving as charge diffusion barrier in the second gate insulating film comprising Si3N4 films 51-53. With this structure, a relatively large positive voltage is given the gate electrode 6 to trap electrons in the Si3N4 film with implantation of ions from the substrate 1. As the electron diffusion in the Si3N4 film is made between the centers of trapping in the film, the film makes possible tunneling of the electrons trapped, but provides a barrier after the removal of voltage. Therefore, after the implantation of charge, there is little change in the threshold voltage thereby ensuring an excellent memory retaining property.


The R/S analysis(rescaled range analysis) is one of efficient methods to characterize nonlinear time series.As the time series of monitoring surface displacement is not only deterministic but also random,the R/S analysis is used to analyze the long-term displacement time series of a landslide in the Three Gorges Reservoir area.The Hurst index of the accumulated displacement-time series and the incremental displacement-time series of the landslide are calculated by using the R/S analysis.The incremental displacement-time series is a more efficient fractal structure,and its Hurst index can depict quantitatively the deformation trend of the landslide.The concept of long range correlated critical time is introduced to analyze the non-periodic cycle length of the landslide displacement.The research indicates that the Hurst index and the non-periodic cycle length at different places of the landslide are different.Based on the physical mechanism of landslide deformation evolution,a conceptual model to determine the accelerating deformation phase according to the Hurst index of the incremental displacement-time series is proposed,and it provides a new method to improve the prediction of landslide failure time.


Introduction The questionnaire, Family Satisfaction in the Intensive Care Unit (FS-ICU-24), was developed to assess relatives' satisfaction with care and involvement in decision-making processes when a close family member stays in the ICU Aim This study was aimed at describing the translation and exploring the psychometric properties of the Norwegian version of the questionnaire. Methods The study design was a cross-sectional survey. After translating the questionnaire according to recommended procedures, 123 close relatives of patients, recently treated in ICU, responded to a mailed questionnaire including the FS-ICU-24-No. Item-to-total correlations and Cronbach's alpha coefficient were assessed for estimating reliability and construct validity was assessed by the "known groups" technique and explorative factor analysis. Results The Cronbach's alpha coefficient of 0.96 and significant item-to-total correlations supported the homogeneity of the instrument. The construct validity was reflected in significant differences in median scores on the total scale and subscales between the group reporting lower degrees of satisfaction and the group reporting higher degrees of satisfaction. Two fixed factors with an eigenvalue >1, and an explained variance of 62.5%, emerged from the factor analysis. Conclusion The FS-ICU-24-No showed promising psychometric properties regarding reliability in this study group, which may indicate that the instrument is suitable for assessing family members' satisfaction with care and decision making in Norwegian ICU.


The invention discloses an instrument capable of implementing automatic detection and sorting of bearing inside diameter. A double-path symmetrical structure is adopted, an inlet sorting mechanism is fixed on one side of a conveyor belt, the side of the conveyor belt is provided with a feeding cylinder and a feeding rod, the other side of the conveyor belt is provided with a station, the station is provided with a station clamping plate and a push plate which are fixed on a station clamping cylinder, the station clamping cylinder is fixed on a station push cylinder, one side of the station is provided with an inside diameter detection mechanism, the station is provided with two gaps which are communicated with a reject outlet and a repair outlet respectively, a reject zone baffle plate and a repair zone baffle plate are arranged on the two gaps respectively, an outlet sorting hopper is fixed at one end of the station, an outlet sorting block is arranged below the outlet sorting hopper, the outlet sorting block is fixed on an outlet sorting cylinder, two sides of the outlet sorting block are provided with an outlet push cylinder and a small groove respectively, and two sides of the small groove are provided with a discharge plate and a discharge frame respectively. The instrument can ensure the reliability of detection on the premise that the detection efficiency of the bearing inside diameter is not reduced, and realizes automation of feeding, detection and sorting.


Coupling radar-rainfall data with distributedhydrological model was important in improving flood forecast precision and leading time.However,radar-rainfall error propagation inhydrological model largely affected runoff process simulation.In this study,the operational radar-rainfall data,provided by Huaihe River basin Meteorological Center,was analyzed.With HEC-HMShydrological model input,radar-rainfall data was used to simulate and analyze the runoff process of rainfall concentration period,in the Xixianhydrological station of Huaihe River basin,during July 1-10,2007.The results showed that runoff simulation based on radar-rainfall data was consistent with the simulation based on rain gauge data.The radar-rainfall input errorhad been decreased obviously after the propagation of the HEC-HMS model.Runoff simulation based on radar-rainfall data by union calibration was the best,whose relative error were-20.2% and-13.3% for flow process and peak flow,respectively.


The practical relevance of the research is the drafting of specific recommendations focused on improvement of the social audit methodology in Transnet in order to facilitate the measurements of sustainable development. This paper consists of an introduction, main part is divided into two sections and organized into six paragraphs in accordance with the above tasks, conclusion, and references. The paper concluded that the social reporting is under development and is used for furthering the sustainable development measurements. It helps to reflect the focus of target audiences on investment, due to the fact that it is aimed at future changes in the reporting and increases the company value in the market.


A novel statistical approach that involves differential shape is proposed to analyze contour segments. First, a moment-based algorithm to represent the differential contour segment in an efficient way is introduced. Then, a curvature mean-shift method is adopted to search for the salient features. An optimized function is also developed to segment a contour into parts based on its structural properties. Compared with some other methods used in CSS (Curvature Scale Space) and shock graphs, our method is more powerful for shape contour analysis, especially for the incomplete or occluded contours. Experiments show that our method can track salient parts in real-time and give a judgment of the basic shape properties such as symmetry.


Four main contributions are made toward understanding stability and clarifying the ambiguity that has surrounded the term stability in the past. (1) Four different aspects of the response of populations to environmental stress-resistance, resilience, persistence, and variability-are given mathematical formulations. (2) Methods are given to analyze a differential equation model of population growth for resistance and persistence, while resilience corresponds to the traditional Lyapunov asymptotic stability. (3) The relation of resistance and resilience to each other depends on the underlying characteristics of negative feedback to population changes and sensitivity of the growth rate to the environment. Strong feedback mechanisms which are independent of the environmental factor causing the stress increase both resilience and resistance, but if the feedback mechanism makes the population growth rate sensitive to an environmental factor, the amount of resilience and resistance under changes in that factor will be inversely related. (4) Increased diversity of resources causes increased resistance to changes in those resources but no significant change in resilience, pointing toward a possible resolution of the stability-diversity question.


Korean manufacturers have developed a new varicella vaccine, NBP608. This phase 3, randomized, double-blind, multicenter study aimed to compare the immunogenicity and safety of NBP608 in healthy children to those of VarivaxTM (control). Children aged 12 months to 12 years were randomized in a ratio of 1:1 to receive either NBP608 or the control vaccine. Serum samples were obtained before vaccination and within six to eight weeks after vaccination. In total, 499 participants (NBP608, n = 251; control, n = 248) were enrolled. The seroconversion rate (SCR) measured using a FAMA assay was 99.53% in the NBP608 group, and the lower limit of the 95% confidence interval (95% LCL) for the SCR difference (NBP608 minus the control) was 0.52%. This 95% LCL for the difference was higher than the specified non-inferiority margin of −15%. In an assessment using gpELISA, the SCR was 99.53% in the NBP608 group, and the 95% LCL for the SCR difference was 6.5%, which was higher than the specified non-inferiority margin of −15%. There were no significant differences between the NBP608 and control group with respect to the proportions of participants who demonstrated local and systemic solicited AEs. This study indicated that NBP608 had a clinically acceptable safety profile and was not immunologically inferior to VarivaxTM.


The success of the Internet has significantly changed how people interact with each other. Rich social interactions nowadays take place online. Users read, shop, chat, work, and play on the Internet. However, unlike many social interactions in the physical world, the Internet has largely hidden the identity attributes of online users. "On the Internet, nobody knows you are a dog," says the famous Peter Steiner cartoon. While anonymity has brought much benefit, including protecting user privacy and free speech, it also poses considerable security threats to online activities. What to believe and whom to believe on the Internet remains extremely challenging. Naive users may easily become victims of online scams by individuals that hide their real identity. There have been numerous incidents where scammers defrauded users [1,6] through email or online social networks. Users with vested interest in a company have been caught creating fake positive reviews for the company's products or services [5]. Pedophiles and underage users may lie about their ages during online chat sessions and to gain access to age-restricted sites. This problem largely stems from the fact that there is currently no lightweight and effective way to verify the identity attributes (such as age and location) of online personas. The typical approaches for establishing online identities involve offline manual verification of users. For instance, a bank may require a user to bring a government-issued ID before opening an online account. Additionally, users may purchase digital certificates that are verified and issued by trustworthy authorities such as VeriSign. These approaches, albeit effective, are heavyweight and often an overkill for many online interactions. Manual verification is slow and costly. It can become the bottleneck that prevents an online service from scaling to hundreds of millions of users. In addition, strict user authentication typically controls access to sensitive or critical resources such as bank accounts or internal networks. Instead in many realistic Internet settings, services or users do not require strong authentication, yet they may benefit greatly from partial or likely-to-be-true user identity information. For example, it suffices for an age-restricted site to know whether a user belongs to an age group, not who the user is or his exact age. Similarly, an online dating service user may desire to know whether another user's location or profession information is likely to be credible before initiating contact. These examples motivate the design of FaceTrust, a system that enables online personas to cost-effectively obtain credentials that verify the credibility of their identity statements. In this paper, we refer to credibility as a measure of the likelihood that a user's assertion is correct or true. FaceTrust achieves this goal by mining and enriching information embedded in Online Social Networks (OSNs), and extends an OSN to provide lightweight, extensible, and relaxed digital credentials. We observe that OSNs already allow users to express a limited form of trust relationships using friend links. We propose to extend this ability by allowing users to tag how credible they consider their friends' assertions, such as the identity information they post on their profiles. This process is similar to real-world background check employed by government agencies but is greatly automated by using online social networks. As an example, a user that wishes to obtain an age certificate from his OSN provider may post on his profile that he is above 18. The user would request from his friends to tag his assertion as true or false. The OSN provider would analyze the annotated social graph to obtain the credibility of the user's friends and subsequently compute the credibility of the user's assertion. It would then issue to the user a credential in the form of {assertion, credibility}. Online services or users could use this OSN-issued relaxed credential to inform their interactions with the user. We face several main challenges in realizing the above vision. First, how can the OSN reliably verify assertions made by users (§ 3.1, § 3.2, § 3.3)? Second, how can an OSN provider export the credibility information of assertions to verifiers without violating a user's privacy (§ 3.4)? Lastly, how can we evaluate the effectiveness of our design (§4)? The main body of this paper describes our initial approaches towards addressing these challenges. We begin with a high-level overview of FaceTrust and several of its motivating examples.


We construct representations pi r of the quantum algebra Uq(sl(n)) labelled by n-1 complex numbers ri and acting in the space of formal power series of n(n-1)/2 non-commuting variables. These variables generate a flag manifold of the matrix quantum group SLq(n) which is dual to Uq(sl(n)). The conditions for reducibility of pi r and the procedure for the construction of the q-difference intertwining operators are given. The representations and q-difference intertwining operators are given in the most explicit form for n=3.


This article deals with the issue of professionally oriented foreign language teaching in non-linguistic universities. The article discusses differentiated approach to teaching foreign languages as well as the use of ICT technologies in this educational context.


Objective To investigate the status of the mental health of the students from divorced families and to find out the influent factors of mental health. Method 579 secondary school students from Zhujiang delta Guangdong province were administered by Mental Health Test(MHT) and Attitude and evaluation to Family. Result the divorced group distinctly differed from the intact one in the attitude and evaluation to family, while other scores between two groups were the same. Conclusion Stepwise regression analysis revealed that three factors were correlated to mental health of secondary school students in divorced family, and they were lack of the pride in family, the persecution of interpersonal relation and negative coping style.


This study has the purpose of approaching,theoretically, the issues of legitimacy and social pertinence ofthe learning processes in professional training for...


The effects of internal acoustic excitation on the leading-edge, separated boundary layers and the aerodynamic performance of NACA 633-018 cross section airfoil are examined as a function of forcing level and forcing frequency of the introduced acoustics. Tests are separately conducted in two suction, open-typed wind tunnels at the Reynolds number of 3.0 x 10 s for the measurements and 1.0 x 10 4 for the visualization. Results indicate that the flow separation is delayed at the angles of attack higher than the stalled angle of small level excitation with the forcing frequency fe near the shear layer instability frequency ft. As the forcing level is increased to some extent, the velocity fluctuations around the slot exit are demonstrated to be the primary governing parameter for modifying the separated boundary layers. Data also show that the effective forcing frequency (and the Strouhal number, 50 extends over wider range as compared to the lower level excitation. Meanwhile, the pressure distributions on the airfoil surface exhibit recovery behaviors with different forcing frequencies. The corresponding boundary layers are visualized to be reattached to the surface to form a recirculation region when the airfoil is around at the stalled angles.


The 2005-07 spike in petroleum prices topping out at $100 a barrel has prodded economic planners across the globe to reconsider their energy options in an age of growing concern over global warming and carbon emissions. The Southeast Asian economies, themselves beneficiaries of an oil and gas export bonanza through the 1970s-1990s, also find themselves in an energy crunch as once ample reserves run down and the search is on for new and cleaner energy supplies. Notably, regional leaders at the 13 ASEAN Summit meeting held in Singapore in November 2007 issued a statement promoting civilian nuclear power, alongside renewable and alternative energy sources. ASEAN--which in 1971 endorsed a nuclear-free zone concept--also sought to ensure that plutonium did not fall into the wrong hands through the creation of a "regional nuclear safety regime." In response, environmental activists across the region cited concerns over nuclear power, citing safety and unstable regional geologies concerns. [1] Undoubtedly they were taking a cue from Japan's recent nuclear disaster. [2] Singapore, host of the ASEAN summit meeting, made known its concerns. The 13th ASEAN Summit meeting held in Singapore in November 2007


Objective To estimate the rapid diagnosis value of the multimedia computing microscope in detecting the sexually transmitted diseases (STD) in females. Methods Intravital specimen was carried out by being smeared onto slices to observe the major pathogens of STD under the multimedia microscope produced by Fortune company (ACT-2000). Results In the 2317 detected specimen, pathogens can be detected immediately and accurately with the same specimens. Conclusion Applying the multimedia computing microscope offers a new efficiency method in detecting and diagnosing the STD in females.


Research studies have described the morbidity associated with inherited bleeding disorders such as hemophilia and von Willebrand disease in women, but their effect on daily living has long been underrecognized. This systematic review sought to document the lived experience of women with a bleeding disorder by assessing research findings on quality of health care, socioeconomic factors, and mental health.


Let L be a completely distributive commutative subspace lattice or a subspace lattice with two atoms, we use a unified approach to study the derivations, homomorphisms on Alg L . We verify that the multiplier algebra of Alg L∩K ( H ) is isomorphic to Alg L and Alg L is zero product determined. For T in M n ( C ), n > 2, we show that A T is zero product determined if and only if every local derivation from A T into any Banach A T -bimodule is a derivation. In addition, we establish some equivalent conditions for an algebra to be zero product determined. For countable dimensional locally matrix algebras and triangular UHF algebras, we also show that they are zero Lie product determined.


Objective—To analyze the GNRHR in patients with normosmic isolated hypogonadotropic hypogonadism (IHH) and constitutional delay of growth and puberty (CDGP). Design—Molecular analysis and in vitro experiments correlated with phenotype. Setting—Academic medical center. Patient(s)—110 individuals with normosmic IHH (74 males) and 50 with CGDP. Intervention(s)—GNRHR coding region was amplified and sequenced. Main Outcome Measure(s)—Novel variants were submitted to in vitro analysis. Frequency of mutations and genotype-phenotype correlation were analyzed. Microsatellite markers flanking © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved Address all correspondence to: Leticia F. G. Silveira. Av. Dr. Eneas de Carvalho Aguiar, 155, 2° andar, Bloco 6. CEP 05403-900, São Paulo, São Paulo, Brasil. Phone: 55 11 2661 7512, Fax: 55 11 2661 7519. email@example.com. Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Authors have no conflict of interest NIH Public Access Author Manuscript Fertil Steril. Author manuscript; available in PMC 2015 September 01. Published in final edited form as: Fertil Steril. 2014 September ; 102(3): 838–846.e2. doi:10.1016/j.fertnstert.2014.05.044. N IH -P A A uhor M anscript N IH -P A A uhor M anscript N IH -P A A uhor M anscript GNRHR were examined in patients carrying the same mutation to investigate a possible founder effect. Result(s)—Eleven IHH patients (10%) carried biallelic GNRHR mutations. In vitro analysis of novel variants (p.Y283H and p.V134G) demonstrated complete inactivation. The founder effect study revealed that Brazilian patients carrying the p.R139H mutation shared the same haplotype. Phenotypic spectrum in patients with GNRHR mutations varied from complete GnRH deficiency to partial and reversible IHH, with a relatively good genotype-phenotype correlation. One boy with CDGP was heterozygous for the p.Q106R variant, which was not considered pathogenic. Conclusion(s)—GNRHR mutations are a frequent cause of congenital normosmic IHH and should be the first candidate gene for genetic screening in this condition, especially in autosomal recessive familial cases. The founder effect study suggested that the p.R139H mutation arises from a common ancestor in the Brazilian population. Finally, mutations in GNRHR do not appear to be involved in the pathogenesis of CDGP.


the semiclassical model for nonadiabatic electron transfer has been described.Some new features for the relations between the energy barrier (E_c) at the crossing point and the activation energy(E_a) in the Arrhenius rate law have been revealed.The complex, reac tants, and the transition state for the colinear reaction have been optimized at 4-31G augmented with a set of anion diffuse functions. After a successful UHF SCF calcula tion due to a electron-located initial guess, the authors have obtained the electron transfer matrix element V_(AB)= 7. 0 kJ/mol , the energy barrier E_c= 28. 4 kJ/mol , the rate constant k=9. 2 × 10 ̄8/s at 300 K. The discussions for the theoretical model and the calculated results have been made.


In this section, we keep our analysis of the communication system simple by considering purely digital systems. (Recall that the transmitted signal from an antenna is an analog waveform.) To do this, as shown in Figure 5, we assume all non-source-coding parts of the system, including the physical (analog) channel, can be combined into an "equivalent channel" which we shall simply refer to in this section as the "channel".


The invention relates to a resin combination containing inorganic powder, a pattern forming method and an electrode manufacturing method. The invention provides the resin combination containing inorganic powder, which has excellent operation/ preservation stability, does not reduce developing property and can form an electrode with excellent pattern shape well. The resin combination containing inorganic powder at least contains (A) conductive particles, (B) glass particles with a refractive index as 1.5 to 1.8 and a glass softening point as 450 to 600 DEG C, (C) an adhesive resin with a glass transition temperature (Tg) as 50 DEG C below zero to 50 DEG C, (D) a photosensitive substance with a solidified glass transition temperature (Tg) as 0 to 100 DEG C, (E) a photo-polymerization evocating agent and (F) fatty acid amide.


The head-wart found in the snail, Euhadra peliomphala, consists of a number of elevated dermal tubercles covered by a particularly thick epithelium. The head-wart and its epithelial cells attain full size by rapid growth at the time of sexual maturation. When two snails meet in the breeding season, their head-warts become conspicuously protuded. After touching the partner's head-wart with large tentacles, each becomes excited, protrudes its penial mass, and finally copulates. Protrusion of the head-wart and copulation are observed at the same time. By the use of head-wart extract similar sexual behavior can be experimentally induced in snails. From these observations, it may be concluded that it is the epithelial surface of the head-wart of a sexually mature snail which releases the substance that promotes sexual behavior. This physiologically active substance is considered to be a kind of sex pheromone. This pheromone does not appear to serve as a sexual attractant but serves rather to sexually excite another snail thus evoking a courtship response following their initial encounter.


In this paper we consider a queuing process in which there are two mean arrival and service rates. Not only does the system randomly change from one mode of service and arrival to the other, but units arrive at random and require varying amounts of service. Analytic expressions are obtained for the generating functions, the mean queue length, and the mean waiting time. Several practical illustrations are given.


Transitions into and out of correctional facilities for people living with HIV are a pivotal point in the HIV treatment cascade where adherence metrics are significantly affected. In this paper I use Alvesson and Sandberg's problematization method of literature analysis to critique and understand the taken-for-granted assumptions underpinning how knowledge is generated within the intersecting fields of HIV, transitions, and corrections. Utilizing problematization, two assumptions underpinning knowledge generation are identified: the linearity of the HIV care continuum model and the tendency to create and perpetuate spatially segregating metaphors of transitions inside versus outside correctional facilities for people living with HIV. These assumptions are discussed in the context of how they shape dominant ways of thinking and practicing in the field. An alternative way to understand transitions for people living with HIV is proposed along with recommendations to guide the HIV care practices of nurses and other healthcare providers.


Training and recruiting nurses for colonoscopy is an attractive cost-saving solution and can help with the extra workload that colorectal cancer screening programmes can create. In this article, Dr Mohammad Imran Khan, Robert Khan and Wanda Owen surveyed the views of health managers in New Zealand regarding the introduction of nurse endoscopists in health services and found that while the majority of managers were supportive of the nurse endoscopist role, few have current plans in their hospital for the introduction of nurse endoscopists


Horses with Streptococcus equi subsp. zooepidemicus (Strep. zoo.) pneumonia were given two doses of sustained release ceftiofur 4 days apart, and a clinical cure occurred in 69.1% of treated horses compared with 31.6% of placebo horses. Authors' addresses: Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50010-1250 (McClure); Pfizer Animal Health, 333 Portage Street, Kalamazoo, Michigan 49007 (Sibert, Hallberg); and Microbial Research Incorporated, 2649 East Mulberry Street #15, Fort Collins, Colorado 80524 (Bade); e-mail: firstname.lastname@example.com. © 2010 AAEP.


This report describes a three-year research project and results performed as the Strategic Highway Research Program 2 (SHRP) Project R03. The research scope involved studying factors associated with workforce fatigue and stress in the rapid renewal environment and the risks to worker safety and construction productivity. The study team developed an integrated fatigue management toolkit, including work scheduling and work practice guidance based on fatigue models, organizational practice guidance, fatigue management reference material, and training materials for managers and workers. This suite of products was prepared with the goal of integrating applicable components into existing safety management systems for highway projects, thereby reducing fatigue risk and increasing safety.


As crowdsourcing has been applied to a variety of disciplines, e.g. marketing and operationalization, more and more scientists turn their sights to how the crowd innovate software engineering to produce high quality software. However, they mainly focus on the impacts brought by domain experts or experienced developers on developing and managing open source softwares, whereas how softwares are influenced by the ordinary people e.g. end users is seldom discussed and easily omitted. To fill up the research gaps, we investigate into commercial application improvement paradigm with assistance of user crowd. The approach focuses on end users by proposing a workflow loop to form a healthy cycle between them and applications. Especially, the approach propose a suggestion model to encourage users to participate into application runtime adaptation. So far, a prototype is developed to enable the crowd to raise and modify their advices, and our prior work has proven the effectiveness in which applications consider the users' advices to adapt themselves.


e15071 Background: 5-year survival rate in patients with adenocarcinoma of the gastro-esophageal junction or stomach (AGE/S) in UICC stage I is reported to be 60-80% only (Holscher et al, 2009; Sie...


Co-doped barium titanate (BT) piezoceramics are applied in advanced energy harvesting systems. In the present study, Ba1−2xHo2xTi1−xMnxO3 (x = 0, 0.02, 0.04, and 0.06) were produced via the sol-gel-assisted solid state co-doping technique followed by microwave and conventional heating. In the current investigation, the synthesizing and phase characterization, allotropic transition, morphological examination, elemental analysis and dielectric-piezoelectric responses were investigated by x-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC) and Thermo-Gravimetric Analysis (TGA), Field-Emission Sanning Electron Microscope (FESEM), Energy-Dispersive x-ray Spectroscopy (EDS), Mapping analysis and inductance-Capacitance-Resistance meter (LCR meter) techniques, respectively. The XRD pattern and DSC/ TGA outcomes demonstrated that tetragonal BT phases without minor BaCO3 secondary phases are synthesized properly, and that the negligible unsolicited BaCO3 phases are thoroughly calcined by a microwave at 900 °C. Doping resulted in an increase in tetragonality (c/a) of 0.19%, 0.15%, and 0.04%, respectively, compared to the pure calcined BT. Additionally, the crystallite size of BT decreased significantly by 59%, 58%, and 52%, respectively. The results revealed that the microwave-sintered samples have higher purity, drastic delicate and finer grain size distribution, and superior tetragonality with respect to the conventionally sintered furnace samples. Furthermore, the piezoelectric constant for the microwave sintered and the conventionally sintered samples with the same value of x = 0.04 were 390 and 370 (pC/N), respectively, which established that the sintering method has satisfactory affection (approximately 6%) on the piezo function of the samples. Eventually, the prepared samples which had 0, 2, 4, and 6% moles of Ho3+-Mn2+ cations and were sintered by a microwave compared to the similar specimens fabricated by the furnace had superior dielectric constants of 2.6, 1.1, 2.2 and 2.9 times, respectively.


The present paper describes a torque controller for a vehicle equipped with 4 electric motors, one at each wheel. The controller is set up to ensure two main functions: braking with anti-skidding and traction control using the electric motor torque as the unique actuator signal source. Unlike the torque generated by classic internal combustion engines, the torque of electric motors is available almost instantaneously. In addition, it can be measured on-line, which means that advanced control techniques can be applied. In order to generate the appropriate anti-skid or anti-slip torque for each wheel, one has to estimate the friction between the wheel and the road. In the first step, the instantaneous friction coefficient and the maximum friction coefficient between the wheel and the road are estimated, without prior knowledge of the road conditions. Next, the approach relies on a feedback sliding mode control scheme to ensure the vehicle is operated in the maximum friction zone in both hard acceleration and braking phases, along with a given reference speed to track. The only variables used in this strategy are the wheel acceleration, the instantaneous torque generated by the electric motors and the chassis acceleration.


Objective:To discuss the clinical value and limitation in evaluating the coronary artery stents by 16-slice CT coronary angiography.Methods:To analyse retrospectively the results of 16-slice CT coronary angiography of 27 cases who had experienced percutaneous coronary intervention,and to compare with the results of catheter angiography.Results:In the 34 coronary artery stents of 27 cases,there were the 26 coronary artery stents(76.47%)whose CT image can meet the lumen evaluation.Of these coronary artery stents whose CT image can meet the lumen evaluation,the sensitivity,specificity,positive and negative predictive value in showing of moderate or moderately above stenosis(≥50%) by 16-slice CT were 66.67%,94.12%,85.71% and 84.21% respectively.If including the 1 moderate stenosis whose CT image can not meet the lumen evaluation,the sensitivity was 60%.The sensitivity,specificity,positive and negative predictive value in showing of high stenosis(≥75%) by 16-slice CT were 50%,95.24%,66.67% and 90.91%.Conclusion:The 16-slice CT can partially replace the catheter coronary angiography in screening of initial diagnosis and interventional therapy for moderate and high stenosis of coronary artery stents.


BACKGROUND
Bevacizumab has provided encouraging results in relapsed glioblastoma multiforme (GBM). Pre-clinical and clinical investigations also showed that continuous low-dose temozolomide has some antiangiogenic activity. Based on this evidence, a phase II trial was designed to investigate an oral regimen of sorafenib, an oral multikinase inhibitor, and metronomic temozolomide for relapsed GBM.

PATIENTS AND METHODS
Forty-three patients (median age=60.0 years) naive for antiangiogenic agents received 400 mg sorafenib twice daily plus TMZ 40 mg/m(2)/day until disease progression.

RESULTS
Toxicity, mostly grade 1-2, was manageable. Grade 3-4 toxicities were hand-foot syndrome (n=4), hypertension (n=2), and fatigue (n=3). Five patients (12%) achieved partial response, 18 (43%) stable disease, 20 (48%) showed progression. The median time-to-progression was 3.2 months, 6-month progression-free survival was 26%, and median overall survival was 7.4 months.

CONCLUSION
This combination of sorafenib and temozolomide was feasible and safe, showing some activity in patients with relapsed GBM.


The thermal conductivity of oxide thin films deposited using dc, rf, and ion-beam sputtering is measured in the temperature range 80--400 K using the 3{omega} method. Thermal conductivity data for amorphous thin films of SiO{sub 2} are nearly identical to bulk {ital a}-SiO{sub 2}. Data for amorphous Al{sub 2}O{sub 3}, while having a magnitude and temperature dependence similar to bulk amorphous oxides, show a dependence on deposition method; rf sputtering of an Al{sub 2}O{sub 3} target produces films with a thermal conductivity 35% smaller than films prepared by ion-beam sputtering. Microcrystalline thin films show a rich variety of behavior: the conductivity of TiO{sub 2} films depends on the substrate tempreature {ital T}{sub {ital s}} and approaches the thermal conductivity of bulk TiO{sub 2} ceramics when {ital T}{sub {ital s}}{congruent}400 {degree}C; HfO{sub 2} films show glasslike thermal conductivity independent of annealing temperature up to 900 {degree}C; and MgO films display a crystalline thermal conductivity that is greatly reduced relative bulk values.


Recent studies demonstrate that the invasion and metastasis of gastric cancer (GC) is closely associated with a multi-subunit vacuolar H + -ATPase (V-ATPase). Here we investigated the expression and role of the human ATP6V1A gene that encodes the catalytic subunit A of V-ATPase in GC. We found that ATP6V1A expression level is significantly elevated in GCs compared to normals, but GC patients with higher expression levels of ATP6V1A have a better prognosis. Genomic analysis revealed that APT6V1A copy number is gained in a small fraction of GC patients and lost in a minimum number. Moreover, the ATP6V1A copy number was positively correlated with its mRNA level. To explore additional mechanisms by which ATP6V1A overexpressed in GCs, we investigated the relationship between transcription factor YY1 and ATP6V1A, and found that mRNA expression of YY1 had significant correlation with that of ATP6V1A . To validate that YY1 transcriptionally regulates ATP6V1A , we discovered that the ATP6V1A core promoter region contains three YY1 binding sites. Moreover, RNAi-mediated knockdown of YY1 in GC cells significantly decreased ATP6V1A mRNA and protein expression, while YY1 overexpression increased ATP6V1A expression level. In conclusion, YY1 may play an important regulatory role in ATP6V1A expression with potential mechanistic and clinical implications in GC. gene by both endogenous and exogenous factors is largely unknown, this study set to address the transcriptional regulation of this gene in two human GC cell lines. We first functionally cloned the promoter region of the ATP6V1A gene and studied its binding domains and interaction with the transcription factor Yin Yang 1 (YY1) that possesses multiple functions in a variety of biological processes as well as in the occurrence and development of tumors. In addition, YY1 has been reported to be upregulated in human cervical carcinomas and may serve as a potential therapeutic target for the treatment of HPV-positive cervical cancer 28 . RNAi-mediated knockdown and over-expression of YY1 in HGC-27 and AGS gastric cancer cells in a reporter gene system led to corresponding changes in ATP6V1A mRNA and protein expression. Thus, we conclude that the expression of ATP6V1A in human GC cells is positively regulated by YY1. (Reads Per Kilobase of transcript per Million mapped reads) and then compare the expression of ATP6V1A between normal stomach and GC tissues. The information about copy number change, mutation, expression levels of ATP6V1A and YY1 in the TCGA study were obtained from the cBioPortal for cancer genome (http://www.cbioportal.org/). The clinical information of TCGA patients was retrieved from the website (http:// www.cbioportal.org/study?id = stad_tcga#clinical).


The effects of solution treatment on the microstructure and mechanical properties of Al-Li-Cu-Mg-Ag-Zr alloy were investigated by means of tensile test,conductivity test,differencial scanning calorimeter(DSC),energy dispersive X-ray(EDX),optical microscopy(OM),scanning electron microscopy(SEM) and transmission electron microscopy(TEM),respectively.The results show that the tensile strength and hardness increase first and then decrease with the increase of the solution temperature when the solution holding time is 30 minutes.The optimal mechanical properties of the alloy are reached at 520 ℃.When the alloy is treated at 520 ℃ for different time,the mechanical properties increase first and then decrease with the increase of solution holding time.The alloy obtains the optimum pattern of microstructure with a large quantity of dispersive fine T1 phase and best mechanical properties when it is treated at 520 ℃ for 30 minutes.The fracture mechanism of the alloy is mixed fracture consisting of transgranular fracture and intergranular layered cracks.The alloy gets overburnt when the solution temperature is 525 ℃.


Ferroelectric thin films are used in a wide range of device applications from MEMS sensors and actuators to non-volatile random access memories. The wide range of applications is due to several attractive properties of ferroelectrics such as high dielectric permittivities and reversible spontaneous polarization. The domain structure of a ferroelectric film has a large influence on the properties of the film and therefore controlling the domain structure is essential to optimize their properties and performance. Furthermore, different applications of ferroelectric thin films need different domain structures for optimum performance. Domain engineering has been achieved by control of the misfit strain through epitaxial growth on substrates with different lattice constants. However, this method only influences the relative domain populations and does not allow specific control over the domain structure. Here we report domain engineering in ferroelectric thin films by using a nanopatterened bottom electrode. Pulsed laser deposition epitaxial grown ferroelectric thin films of PbTiO3 and BiFeO3 have been grown on self assembled SrRuO3 nanopatterns 5nm thick and with lateral dimensions of 100-200nm. The patterned SrRuO3 changes the mechanical boundary conditions of the ferroelectric film and as a result new domain structures are obtained with features corresponding to the SrRuO3 patterns. This technique allows nanometer control of the domain structure in ferroelectric films that has not previously been achieved.


PIU(Pathological Internet Use) or the Internet Addiction Disorder(IAD),the problematic Internet Use,the incidence of which is about 6%~14%.It's a mental barrier among young people that has received public attention.STROOP paradigm was adopted in the initial research of the cognitive characteristics of PIU.It was found that the RT of PIU subjects on Internet-related words and emotional words were longer than normal group.They can speculate if there may be cognitive processing and emotional processing through RT.However,these paradigms couldn't ensure the basic characteristics of the cognitive and emotional processing.A total of 454 college students were chosen according to the Adolescent Pathological Internet Use Scale(APIUS),of which 31 were PIU students as the subjects of this experiment.Another 31 students were selected randomly from the non-PIU subjects as the control group.There was no significant difference between the two groups in gender and age.The experimental materials were 60 pictures connected with words.Each first character had 3 alternative last characters ranging from positive,neutral to negative to form 2-character word.The positions of the last character were random in the experiment.The subjects were required to choose the proper character.Their choices and the RT are recorded.The research adopted a 3(positive,negative or neutral)×2(priming types:happy,sad,non-priming)×2(PIU and non-PIU) mixed design.The group with PIU/non-PIU was the between-subjects design,others were the within-subjects designs.There was a significant difference among the three sorts of words,For all the subjects,65.34% of the words they chose were positive words,21.1% were neutral words,13.5% were negative words.The PIU subjects chose less positive words but more negative words than the non-PIU group.the subjects with or without PIU chose positive words more(there was a significant difference),and negative words less(there was a significant difference in the non-PIU group,but not in the PIU subjects).There was a significant difference in the chosen of positive words between PIU group and the non-PIU group in the sad priming.In different priming types,however,there was only a nearly significant difference for negative words between the two groups.There was a significant difference among the RT of different type of words:the RT of negative words was the longest;the RT of positive words was the shortest.The RT for the positive words of PIU subjects was longer than the non-PIU group,but shorter for the neutral words and negative words and the difference was significant.For the two groups,the RT in the happy priming was the longest,that in the no-priming one was the second,and that in the sad priming was shortest.But only in the condition of happy priming,the PIU subjects chose more quickly than those from another group,there was a significant difference but not in other priming conditions.In the sad priming condition,the RT for the positive words of PIU subjects were longer than neutral and negative words.In other priming conditions,there was no significant difference between the RT of two groups.All the subjects chose the positive words most and the negative least,which showed a cognitive choose tendency of which is "happy approach and pain avoidance".The PIU group chose less positive words but more negative words than the non-PIU group,.In the happy priming condition,the choice of negative words was increased for all the subjects,but in sad priming condition,the choice of positive words was increased.In the condition of sadness priming,PIU students chose less positive words and more negative words than non-PIU students.All the subjects chose positive words most quickly,and negative words most slowly.Compared with the non-PIU students,PIU students chose positive words more slowly,negative words and the neutral words more quickly.The RT of both groups was longest in the condition of happy priming,least in the sadness priming.In the condition of the happy priming,the RT of PIU subjects were shorter than non-PIU subjects,but the opposite in the sadness condition.In the condition of sad priming,the PIU student spent more time choosing the positive words and less time choosing the negative words than another group.


British empirical aesthetics is a typical case of natural scientific approach to aesthetic study.Though natural scientific approach has exerted profound influences upon both western aesthetics in the 20th century and contemporary aesthetics in China,the validity of its application to humanities is limited.Thus the author claims that contemporary hermeneutics sheds light on the aesthetic study.


In the literature, mixtures of distribution functions have been applied to find new distributions with properties of interest in reliability, such as bathtub shaped hazard rate functions, and others. In general, the distribution function of a mixture has a complex analytic expression. We propose the study of a class of distributions involving phase-type distributions in order to modelize the lifetime of devices and systems. The phase-type distributions are a closed class for finite mixtures, so the distribution of the mixture of these distributions is a phase-type distribution. This class is closed for the formation of coherent systems, convolution, and ordered statistics. We present two special cases of mixtures, the one of three Erlang distributions, and the one of infinite geometric mixture of convolutions of Erlang distributions. In this way, we use well-known distributions each one involving two parameters. We show that the class of these mixtures includes distributions with bathtub shape failure rate. Also, we have obtained other. We are performing computer-experimental methods to fit these distributions to other distributions frequently used in modelizing lifetimes.


EMDR Treatment: Overview and Integration Beyond the Talking Cure: Somatic Experience and Subcortical Imprints in the Treatment of Trauma- Bessel A. van der Kolk The Developing Mind and the Resolution of Trauma: Some Ideas About Information Processing and an Interpersonal Neurobiology of Psychotherapy- Daniel J. Siegel EMDR and Psychoanalysis- Paul L. Wachtel EMDR and Cognitive Behavior Therapy: Exploring Convergence and Divergence- Nancy J. Smyth and A. Desmond Poole EMDR and Schema-Focused Therapy: The Whole May Be Greater Than the Sum of the Parts- Jeffrey E. Young, William M. Zangwill, and Wendy E. Behary EMDR: An Elegantly Concentrated Multimodal Procedure?- Clifford N. Lazarus and Arnold A. Lazarus EMDR and Hypnosis- Stephen Gilligan EMDR and Experiental Psychotherapy- Arthur C. Bohart and Leslie Greenberg Feminist Therapy and EMDR: A Theory Meets a Practice- Laura S. Brown EMDR in Conjunction With Family Systems Therapy- Florence W. Kaslow, A. Rodney Nurse, and Peggy Thompson Transpersonal Psychology, Eastern Nondual Philosophy, and EMDR- Sheila Krystal, John Prendergast, Phyllis Krystal, Peter Fenner, Isaac Shapiro, and Kali Shapiro Integration and EMDR- John C. Norcross and Francine Shapiro


A directional image for a fingerprint obtained from an expanded second stage Haar wavelet transform is presented. This directional image represent the orientation pattern that later on are used for fingerprint matching so that the real owner can be identified. To construct the directional image, we first perform a second stage Haar wavelet transform on a fingerprint. Due to the limitation of the Haar wavelet, we use the expanded version of it instead so that a better directional image can be obtained. Next, we quantize the directional image into a few grey-level values that represent a range of angle orientations. We then smooth the image using an averaging filter. Based on this image we then perform the matching process based on the minimum square error (MSE) criteria.


where · denotes the vector inner product. If a further binarization to the vector I is desired to compress this inner product, it can be achieved via I · V ≈ αβIB · VB , where IB is a binary vector and β is a scalar. If we want to minimize the straightforward approximation error |I ·V −αβIB ·VB | and compute the optimal solution to this optimization problem, an optimal solution, |IB · VB | = 1 and αβ = sign(IB · VB)I · V , can easily be calculated. Unfortunately, this solution possesses a strong dependency on the value of I · V and it tends to lose large amount information of the original vectors. To alleviate this issue, the approximation problem of the inner product I ·V is defined as


It is well known that sin(2�), whereis one of the angles of the unitarity triangle of the CKM matrix, can be determined in a theoretically clean way by measuring mixing-induced CP violation in the decay Bd ! J/ KS. Another clean extraction of this CKM angle is provided by the time-dependent angular distribution for the decay products of Bd ! J/ (! l + l − )K ∗0 (! � 0 KS), where we have more observables at our disposal than in the case of Bd ! J/ KS, so that in addition to sin(2�) also cos(2�) can be probed in a direct way. Unfortunately a sign ambiguity remains in cos(2�). If it could be resolved, a discrete ambiguity in the extraction of the CKM anglecould be resolved as well, which would allow a more incisive test of the CKM model of CP violation. This note shows that detailed time-dependent studies of Bu,d ! J/ K ∗ and Bs ! J/ � decay processes can determine the sign of cos(2�), thereby removing the corresponding ambiguity in the extraction of the CKM angle �.


Thermoresponsive polymers with pendant glucose functionality form aggregates with bacterial cells that can be assembled/disassembled reversibly through temperature cycling. The polymers are chain extended at temperatures below 40 °C and display glucose moieties to solution, whereas above this temperature the globular state of the polymer "hides" the sugar groups. The specificity and reversibility of the glucose display is demonstrated chemically via a boronic acid−alizarin coupled assay and through cell aggregation assays utilizing bacteria with and without fimH sugar recognition sites.


This paper proposes a power management strategy of parallel inveters based system, to enhance the power generation capacity of the existing system with distributed energy sources one has to choose DG source based inverter connected in parallel with the existing system.Two DG sources PV, Fuel cells feeds the DC voltage to two parallel inverters connected to the grid. Fixed band hysteresis current control with Instantaneous p-q power theory is adopted to create an artificial environment. Two parallel inverters are able to deliver the harvested power from PV, FC to grid and able to balance the load Without communication between parallel inverters this controller having the capability of load following, the harmonic components of currents at output of inverter are also very low; this will automatically reduces the circulating currents between parallel inverters. Simulation studies are carried out to investigate the results of PV, FC systems connected to the utility grid.


Through study on suitability of urban public space for old people,the design elements were analyzed,so as to implement solutions for aging problem,make an effective link of architectural and landscape design with other spaces.


In this paper, we introduce a modification of the Fuzzy ARTMAP (FAM) neural network, namely, the Fuzzy ARTMAP with adaptively weighted distances (FAMawd) neural network. In FAMawd we substitute the regular L1-norm with a weighted L1-norm to measure the distances between categories and input patterns. The distance-related weights are a function of a category's shape and allow for bias in the direction of a category's expansion during learning. Moreover, the modification to the distance measurement is proposed in order to study the capability of FAMawd in achieving more compact knowledge representation than FAM, while simultaneously maintaining good classification performance. For a special parameter setting FAMawd simplifies to the original FAM, thus, making FAMawd a generalization of the FAM architecture. We also present an experimental comparison between FAMawd and FAM on two benchmark classification problems in terms of generalization performance and utilization of categories. Our obtained results illustrate FAMawd's potential to exhibit low memory utilization, while maintaining classification performance comparable to FAM.


Advance Metering Infrastructure (AMI) is one of the basic functional blocks of the Smart Grid. It is a system that supports two-way communications with customers and electric company [7]. AMI comprises of components such as the AMI meter, AMI head-end, Meter Data Management System (MDMS), the communication network, the access points, and the endpoints. The AMI systems make use of smart meters, and In-home displays to assist in the determination of the usage pattern and make efficient allocation of resources wherever required. However, increasing usage in Smart Grid services bear huge risks at various points and AMI is one such area that can be exploited by launching malicious attacks that could threaten the mission of the Smart Grid Services [2].


Mathematical models of dynamics of pressure swing adsorption processes for the separation of synthesis gas (into hydrogen, carbon dioxide and carbon monoxide) and air (into oxygen, nitrogen and argon) have been developed. The models allow calculating the profiles of component concentrations and temperature of gas and solid phases, pressure and velocity of gas mixture along the height of adsorbent in relation to time. The models include the following equations: 1) processes of mass and heat transfer during the adsorption (desorption) of a sorptive (H2, CO2, COandO2, N2, Ar) by granulated zeolite adsorbents 5Aand13Х; 2) kinetics of compound diffusion transport of adsorbate and Langmuir-Freundlich isotherm (for the synthesis gas separation), kinetics of external diffusion and Dubinin-Radushkevich isotherm (for the air separation); 3) the Ergun equation for the calculation of pressure and velocity of gas mixture in adsorbent.The system of partial differential equations was solved by method of lines. The system of ordinary differential equations was solved by the fourth-order Runge-Kutta method with automatic step selection.To analyze the accuracy of mathematical models of the adsorption separation of synthesis-gas for recovery hydrogen, the relative error of the mismatch between the calculated values for the model and the experimental values of the concentration of the product (hydrogen, oxygen) in the 'steady state' (after 15-30 operating cycles of the PSA) was calculated. The maximum value of the relative error did not exceed 11.5%.Numerical studies were carried out in a wide range of changes in the time of the cycle "adsorption-desorption" and the pressure at the stage of adsorption to determine the effect of changes in temperature, composition and pressure of the initial gas mixture on the purity, recovery and temperature of production hydrogen and oxygen, as well as the relationship of the PSA unit capacity with the purity of the resulting product (hydrogen, oxygen). The problem of adaptive optimization of the process of adsorption separation of a gas mixture and obtaining hydrogen and oxygen with a maximum concentration was formulated and solved.The algorithmic and software of the automated adaptive control system was developed.


Autobiographical memory, which is close ly tied up with the development of cognition,emotion, personality and sociality of human beings, has long been a "hotspot" in the field of the research on mem ory. The paper reviews the recent evolvement of autobiographical memory, summari zes some new results of the researches, including the definition of autobiographical memo ry's content,its origin and factors working on autobiographical memory. Then th e paper discusses the shortcomings existing in current researches and makes some expectation for the further study.


In this paper we döal with the occurrence of anaphoric expressions in English free adjuncts. This paper is organized äs follows. We first discuss the relevant surface organizations in English free adjuncts. Section 2 describes the possible combinations of the anaphoric expressions and their antecedents in relation to the categorial heads of the free adjuncts. In section 3 we first discuss briefly the organization of a Generalized Phrase Structure Grammar, and then turn to the mechanism needed to induce structures containing free adjuncts. In the final section we provide a description of the occurrence of the anaphoric expressions in terms of the rule System that we have proposed for free adjuncts.


A case of xeroderma pigmentosum of late onset is reported in a boy who later developed a teratoma of the testis.


EUROLOGIC INJURY can be defined as any temporary or permanent injury to the central and peripheral nervous system, including the brain, spinal cord, and peripheral nerves. This is a major perioperative complication of cardiac and aortic surgery, which can manifest as short-term coma or a state of confusion and long-term decline in cognitive function, behavioral changes, or physical dysfunction. Stroke occurs in approximately 2% to 3% of adult cardiac surgery patients. The rate of postoperative cognitive decline is less clear, due to heterogenous testing methods, but is reported in 50% to 70% of patients at 1 week, 30% to 50% at 6 weeks, and 20% to 40% at 1 year. 1,2 This review evaluates the current rationale and evidence for proposed surgical and nonsurgical techniques for the reduction of neurologic injury. A variety of mechanisms can result in perioperative neurologic injury during cardiac and aortic surgery (Table 1), and many patients have a combination of these mechanisms. This review discusses these etiologic factors in relation to the techniques proposed to reduce them. Accurate assessment techniques to determine the etiology of neurologic injury, adequacy of cerebral perfusion, and quantification of the extent of injury are essential to assess the efficacy of potential neuroprotective measures. These techniques include intraoperative near-infrared spectroscopy and transcranial Doppler; neurologic, psychological, and cognitive examination; imaging of the nervous system; and biomarkers in cerebrospinal fluid and serum. Discussion of these methods are outside the scope of this review; however, it is important to appreciate that all methods have limitations in sensitivity and/or specificity when interpreting the results of experimental and clinical studies. 3 A recent consensus statement aimed to unify definitions and classifications of neurologic injury after aortic arch surgery. 4


We present a study of the effective magnetization Meff and the effective damping parameter αeff by means of ferromagnetic resonance spectroscopy on the ferromagnetic (FM) materials Ni81Fe19 (NiFe) and Co40Fe40B20 (CoFeB) in FM/Pt, FM/NM, and FM/NM/Pt systems with the non-magnetic (NM) materials Ru, Cr, Al, and MgO. Moreover, for NiFe layer systems, the influence of interface effects is studied by way of thickness dependent measurements of Meff and αeff. Additionally, spin pumping in NiFe/NM/Pt is investigated by means of inverse spin Hall effect (ISHE) measurements. We observe a large dependence of Meff and αeff of the NiFe films on the adjacent NM layer. While Cr and Al do not induce a large change in the magnetic properties, Ru, Pt, and MgO affect Meff and αeff in different degrees. In particular, NiFe/Ru and NiFe/Ru/Pt systems show a large perpendicular surface anisotropy and a significant enhancement of the damping. In contrast, the magnetic properties of CoFeB films do not have a large influence of t...


One of the main problems facing the cultivation of vanilla (Vanilla planifolia Jacks. ex Andrews) in Mexico and the world isits susceptibility to pests and diseases, among which stands out the root and stem rot caused by Fusarium oxysporum f.sp. vanillae. Although Mexico is the center of origin and domestication of vanilla, there are currently no genetic materialsresistant to this pathogen. For this reason the Institute of Biotechnology and Applied Ecology (INBIOTECA) of theUniversity Veracruzana has undertaken for years a biotechnological genetic improvement program in orderto obtain vanilla genotypes resistant to this pathogen. To this end, plants (regenerated from callus) withhigh percentages of polymorphism obtained in previous studies, were submitted to concentrations of50% (v/v) of Fusarium oxysporum f. sp. vanillae. To date, 27.7% of plants resistant to thisconcentration of fungal filtration have been obtained, which will be evaluatedunder field conditions.


The stereo matching method based on deep learning is developing rapidly. Before the AANet+ adaptive aggregate stereoscopic matching network was put forward, the 3D convolution-based deep learning network occupied the core position, but it had the disadvantage of large number of parameters and high memory consumption in cost volume and cost aggregation. With the advent of AANet+, it solves the defects of 3D convolution to some extent by virtue of deformable convolution and intra-scale aggregation modules and cross-scale aggregation modules. However, there are also shortcomings in AANet+, which uses hourglass stacking modules to start feature extraction from multiscale directions, but uses convolution to lose some of its information when fused. Therefore, this paper uses the channel attention module ECA to improve the feature extraction module of AANet+, and introduces the channel attention module in the traditional hourglass stacking module to extract more rich features. In addition, channel attention modules are introduced to obtain multi-scale features to reduce information loss and increase contextual connections. Experimental results show that the proposed improved network has achieved better results in synthetic data set Scene Flow and realworld scene data set KITTI2015 than AANet+.


We report the molecular characterization and functional analysis of a gene (PsdOAT) from Scots pine (Pinus sylvestris) encoding Orn-d-aminotransferase (d-OAT; EC 184.108.40.206), an enzyme of arginine metabolism. The deduced amino acid sequence contains a putative N-terminal signal peptide for mitochondrial targeting. The polypeptide is similar to other d-OATs from plants, yeast, and mammals and encoded by a single-copy gene in pine. PsdOATencodes a functional d-OATas determined by expression of the recombinant protein in Escherichia coli and analysis of the active enzyme. The expression of PsdOATwas undetectable in the embryo, but highly induced at early stages of germination and seedling development in all different organs. Transcript levels decreased in later developmental stages, although an increase was observed in lignified stems of 90-d-old plants. An increase of d-OATactivity was observed in germinating embryos and seedlings and appears to mirror the observed alterations in PsdOAT transcript levels. Similar expression patterns were also observed for genes encoding arginase and isocitrate dehydrogenase. Transcripts of PsdOAT and the arginase gene were found widely distributed in different cell types of pine organs. Consistent with these results a metabolic pathway is proposed for the nitrogen flow from the megagametophyte to the developing seedling, which is also supported by the relative abundance of free amino acids in embryos and seedlings. Taken together, our data support that d-OAT plays an important role in this process providing glutamate for glutamine biosynthesis during early pine growth.


The vehicles that fly the satellite into a model of the Earth System are observation operators. They provide the link between the quantities simulated by the model and quantities observed from space, either directly (spectral radiance) or indirectly estimated through a retrieval scheme (bio-geophysical variables). By doing so, observation operators enable modellers to properly compare, evaluate and constrain their models with the model-analogue of the satellite observations. This 5 paper provides the formalism and a few examples of how observation operators can be used, in combination with data assimilation techniques, to better ingest satellite products in a manner consistent with the dynamics of the Earth System expressed by models. It describes communalities and potential synergies between assimilation and classical retrievals. The paper explains how the combination of observation operators and their derivatives (linearisations) form powerful research tools. It 10 introduces a technique called automatic differentiation that greatly simplifies both development and maintenance of derivative code.


AIM: To investigate the effects of xinmaining on coagulation time, prothrombin time and euglobulinlysis time. METHODS: After feeding 30 rats on xinmaining liuid, blood of the rats was taken from canthus by use of glass capillary 30 minutes after the last feed and coagulation time was recorded. The blood sample of carotid was drawn out in 24 rabbits 30 minutes after veinal injection of xinmaining and prothrombin time was recorded. After feeding on 32 guinea pigs blood sample was taken from heart 30 minutes after the last feed and euglobulinlysis time was detected. RESULTS: It was found that xinmaining of various concentrations could prolong coagulation time and prothrombin time, and shorten euglobulinlysis time. When xinmaining concentration was greater, coagulation time and prothrombin time were delayed (P0.05 and P0.01),while euglobulinlysis time was shortened(P0.05 and P0 01). CONCLUSION: Xinmaining can prolong coagulation time and prothrombin time, and shorten euglobulinlysis time, indicating its unambiguous effect on blood anticoagulation.


Application of Reosorbilact as an intravenous infusion in the combination treatment of patients with purulent-septic diseases, isolated traumatic brain injuries, pneumonias and operations for internal carotid artery reconstruction has a significant detoxifying effect, which manifests itself in the reduction of concentration of average-weight molecules and lipid peroxidation products. Parameters of blood coagulation system quickly returned to normal, indicating improvement of blood rheology.


The genus Rhynchoglossum in Malesia has been revised. Five species are included: R. borneense, R. capsulare, R. klugioides, R. obliquum and R. spumosum. Rhynchoglossum obliquum is a widespread and common species while the other four are endemic to Malesia. Morphological descriptions, nomenclature, distribution, ecological information and notes are provided for all species. An identification key and a list of examined specimens are included.


The purpose of this report is to find out which floating breakwaters can be utilized in open sea conditions and what can be expected of them. Since every breakwater interferes with the energy of the waves, it is logical that a probable power generation function of floating breakwaters is also investigated. This report is a global review of the literature about floating breakwaters and energy devices. It is not complete, but the most important types are investigated systematically.