Steady and unsteady supercavitating flow around slender wedges is investigated.Solving integral equations of supercavitating flow based on the finite difference time discretization method,some numerical results are obtained.The influence of Froude Number on the length and shape of vertical supercavity is analyzed.The change history of unsteady supercavity's length and shape are investigated when the wedges angel or cavitation number is changed in aperiodic time-dependence,especially in high-frequency impulse.The evolution of unsteady supercavity shape is analyzed qualitatively using G.V.Logvinovich's principle of independence of the cavity section expansion.


There was a lack of detailed information of factors affecting the performance of dairy cattle kept in smallholder farms in Temeke municipal. Two approaches were employed to identify factors that affect the productivity and reproductive performance of dairy cattle kept in the study area. The first approach used structured questionnaire which were administered to 84 dairy farmers using a cross sectional survey technique to collect data from 12 villages. The second approach was a longitudinal monitoring where 16 lactating dairy cattle from four streets owned by dairy farmers that filled the questionnaire were monitored for thirty days where feed intakes and milk yield were measured and recorded. Feed samples were collected for quality evaluation. The daily milk yield of lactating cows under cross sectional survey and longitudinal monitoring was 8 litres with range of 413 litres and 9 litres with range of 5-13 litres per cow per day, respectively. The major limitations to improved production identified by farmers were diseases and erratic extension services. The overall percentage of crude protein (CP), calcium (Ca), Phosphorus (P), In vitro dry matter digestibility (IVDMD) and Metabolisable energy (ME) contents of mixed forages fed to the animals were 6.38, 0.2, 0.17, 44.77 and 7.14, respectively. IVDMD and ME contents of mixed forages fed to cattle in Mbutu village were significantly (P<0.05) higher than those from Kizani, Kidagaa and Kwachale villages. The overall daily nutrient intakes of ME, CP, Ca and P for a cow weighing 420kgs in the study area were 87.5, 758g, 22.9g, and 18.5g per cow per day, respectively which did not meet the requirement for the production of 12 litres of milk per day. According to NRC (2001) a cow weighing 420kg requires 108 ME, 1357gCP, 46.2gCa and 34gP. Therefore supplementary ration of 20.5ME, 599gCP,


Little is known about the prevalence of impaired executive control function (ECF) in community dwelling elderly or minority populations. We have determined the prevalence of cognitive impairment and impaired ECF in a community dwelling Mexican American elderly population, and their associations with functional status.


Based on the study of miniaturization of the coupler, the advantages of using slots to create conditions for additional miniaturization of the structure are considered. In this paper, we propose the implementation of a coupler which consists of a set of lines having high wave impedance and idle loop sets. Slit lines were added to the gaps between the loops, which made it possible to obtain a decrease in the operating frequency. The use of slots can be used to adjust the fabricated coupler.


Large flowmeters are used in many industrial facilities, including power plants, cooling-water stations for refineries, and petrochemical plants. These flowmeters are employed for various purposes, including billing. Just like all machines, flowmeters are subject to failure. Drift is a particular type of failure in which the flowmeter produces an error in measurement that would incrementally increase with time. Maintenance technicians calibrate and fix all measuring equipment, including flowmeters. Nevertheless, downsizing policies and budget cuts in most contemporary industrial facilities have made these technicians overwhelmed with work. A mathematical and computer-based drift-detection scheme is developed to reduce the burden of the maintenance staff. The detection scheme only uses the flowmeter's flow data and the discrete Fourier transform (DFT). The detection scheme was applied over the flow data from an actual flowmeter that drifted during its operation. DFT application over the data produced by the flowmeter led to expected results and other unexpected results. This paper discusses both results and suggests areas for further study. Practically speaking, the scheme would facilitate the early detection of drifts in flowmeters having seasonal flow regardless of type or manufacturer.


Midazolam is commonly used to treat refractory seizures in newborns and as a first‐line anti‐epileptic drug in children. Its use as first‐line treatment of neonatal seizures has not been investigated so far. We retrospectively studied the tolerability of midazolam in 72 newborn infants who received i.v. or i.n. midazolam as first‐line treatment for seizures. No major side‐effect exclusively due to midazolam was reported. The i.n. route was used for 20 patients (27.8%). Effectiveness could not be formally evaluated due to the absence of systematic electroencephalogram recording while midazolam was administered. In conclusion, midazolam was well‐tolerated as a first‐line abortive emergency treatment of neonatal seizure. The i.n. route offers a useful alternative to i.v. phenobarbital or phenytoin in emergency settings.


Precision mass measurements of short-lived isotopes provide insight into a wide array of physics, including nuclear structure, nucleosynthesis, and tests of the Standard Model. The precision of Penning trap mass spectrometry (PTMS) measurements is limited by the lifetime of the isotopes of interest, but scales proportionally with their charge state q, making highly charged ions attractive for mass measurements of nuclides far from stability. TITAN, TRIUMF's Ion Trap(s) for Atomic and Nuclear science, is currently the only setup in the world coupling an EBIT to a rare isotope facility for the purpose of PTMS. Charge breeding ions for Penning trap mass spectrometry, however, entails specific set of challenges. To make use of its potential, efficiencies have to be high, breeding times have to be short and the ion energy spread has to be small. An overview of the TITAN facility and charge-breeding program is given, current and future developments are highlighted and some selected results are presented.


The author discusses three years of experience with the control of instrumentation utilizing GPIB (general-purpose interface bus) control in undergraduate electrical engineering laboratories. A number of conclusions are offered which may be useful for other institutions contemplating going in this direction. At this time the assessment is that the results have been generally positive. Some applications have been quite successful, others have not.<<ETX>>


We introduce a novel class of time encoding machines (TEMs) that exhibit multiplicative coupling, and, feedforward and feedback. We show that a machine with multiplicative coupling is I/O equivalent with an integrate-and-fire neuron with a variable threshold sequence. The same result holds for a TEM with feedforward while a machine with feedback is I/O equivalent with an asynchronous sigma/delta modulator with variable thresholds. For all TEMs, an input band-limited signal can be perfectly recovered from the zero crossings of the modulated signal and the threshold sequence. We present the optimal decoding algorithm and give conditions for perfect signal recovery


In order to clarify the oceans role in the overall geochemical cycle of CO2, getting to know a vertical concentration of phytoplankton is very important. The authors measured the vertical distribution of chlorophyll a in the western equatorial Pacific Ocean during the Research Vessel MIRAI cruse (MR01-K05, MR02-K06), and analyzed a number of data which were measured on the ship. The results show that the phytoplankton distribution has strong correlation with mixed layer depth and compensation depth. Using the CTD and ADCP data, the estimated model for the change of chlorophyll distribution is constructed.


Currently,the rapid development of image processing and editing software makes not only the image forgery and tampering become easier,but also the distinction of the authenticity of the image by visual inspection become tougher.For this reason this paper makes a deep study on its imaging principle and camera response with the digital camera imaging feature as a starting point,and converses the nonlinear distribution of the process of transforming the sensor visibility into image brightness as the maximum posteriori probability model.In accordance with the inconsistent physical characteristics of the response of the different cameras,a method of image authenticity detection based on the normality of the camera response is proposed in this paper.Experimental results show that this method can obtain better recognition results.


As designing practical algorithms of learning from examples, one has to deal with some optimization problems. The major optimization problems are: the smallest feature subset selection, the smallest decision tree induction, and the smallest k-DNF induction. In this paper, we show that all these optimization problems listed as above are NP-hard, and we present new greedy algorithms for solving these problems.


In order to assess corrosion status of waterlogged catalpa wood from Changtaiguan,Xinyang District,Henan Province and provide a scientific basis for protection technology,physical and mechanical properties of unearthed catalpa wood and modern counterpart,such as absolute water content,basic density,compression strength parallel to the grain and degree of crystallization of wood cellulose were determined.Furthermore,micromorphological structure and crystal morphology of above samples were investigated.The maximum water content of unearthed catalpa wood was 4.25 times of the modern counterpart,the basic density was about one third of the counterpart and the compression strength parallel to the grain was 0.04 MPa.The cell wall of unearthed catalpa wood became cavitating and loosening in a wet state.Its middle lamella remained in a good condition and the secondary wall became thin and most of them collapsed and were divorced from middle lamella after supercritical drying.Approximately half of the crystalline cellulose was degraded to run off.It can be concluded that the unearthed catalpa wood from Changtaiguan has been degraded heavily.


To ascertain the status of intellectual capital reporting in a developing nation, this study examined annual reports of the top 30 companies in Sri Lanka. These were analysed using content analysis, and data were recorded in a theoretically backed coding framework with 45 intellectual capital items that were categorized into internal, external and human capital. The findings indicated that the most reported was external capital by frequency and human capital by line count. Only a small proportion of intellectual capital items reported were quantified.


Received: 21 September 2021 Revised: 5 October 2021 Accepted: 6 October 2021 Publication: 21 October 2021 doi: 10.1255/jsi.2021.a6 ISSN: 2040-4565 Citation A. Swanson, A. Herrero-Langreo and A. Gowen, "Comparison of portable spectral imaging (443–726 nm) and RGB imaging for predicting poultry product "use-by" status through packaging film", J. Spectral Imaging 10, a6 (2021). https://doi.org/10.1255/jsi.2021.a6 © 2021 The Authors This licence permits you to use, share, copy and redistribute the paper in any medium or any format provided that a full citation to the original paper in this journal is given, the use is not for commercial purposes and the paper is not changed in any way. 1 A. Swanson, A. Herrero-Langreo and A. Gowen, J. Spectral Imaging 10, a6 (2021)


This paper reviews the debate on the possibility of exercising constitutionality control by the Audit Courts, under the terms of Precedent 347 of Brazilian Supreme Court (STF). Through bibliographic and jurisprudential research, the objective is to understand the recent positions of STF on the applicability of this thesis and to discuss the practical effects of this competence, in light of the institutional characteristics of the Audit Courts. The study concludes that the Precedent 347 is suitable in the 1988 Federal Constitution and offers possible circumstances in which the evaluation of constitutionality can be practiced without major impacts on the institutional order.


In Argentina, outside major metropolitan areas most of the population in the early 1940 decade inhabited at the rural environment. This article seeks to review in the contemporary Gualeguay city newspapers, town located in the south of the province of Entre Rios, the discursive constructions around the figure of rural workers, making visible the reproduction of a class culture that distinguishes and highlights the victims of a social and economic model in transition while condemning the figures identified with an elite loaded with negative values. It aims to be a contribution to the knowledge of regional spaces which were outside the industrialization process, viewed as liabilities to the transformations of exogenous origin.


Cooperative relaying improves the performance of wireless networks by forming a network of multiple independent virtual sources transmitting the same information as the source node. However, interference induced in the network reduces the performance of cooperative communications. In this work the statistical properties, the cumulative distribut ion function (CDF) and the probability density function (PDF) for a basic dual hop cooperative relay network with an arbitrary number of interferers over Rayleigh fading channels are derived. Two system models are considered: in the first system model, the interferers are only at the relay node; and in the second s ystem model, interferers are both at the relay and the destination. This work is further extended to Nakagami-m faded interfering channels. Simulation results are presented on outage probability performance to verify the theoretical analysis.


This study attempts to provide a theoretical framework for the appreciation of music among the Benin, a strategic ethnic group in Nigeria. It investigates how concepts such as folk and popular song, music, noise, speech and sound find their relevant expression and place in the sociocultural, economic, moral and even psychological setting of the Benin world. Finally, it is discovered that a conceptual approach is crucial, not only to the situation of the Benin oral literary values within a Western ideological context, but also in the facilitation of an objective evaluation of critical aspects of the life of people.


Vermiculture efficiency of two endemic earthworm species i.e., Perionyx ceylanensis and Perionyx excavates was compared in different organic wastes such as municipal solid waste (MSW), sugarcane trash (ST), paddy straw (PS) and farm yard manure (FYM) to check the suitable substrate. The percentage decomposition, total biomass of the worms recovered, the total number of worms and the cocoons recovered were high in the treatment, which contained FYM and cowdung (CD) (1:1). The worm meal of P.ceylanensis cultured in various substrates was subjected to molecular characterization, in which the isolated DNA did not show any descriptive changes in the bands obtained. The molecular weight of the band was found to be 13400 bp in all the substrates. The RNA showed some changes in the bands, the molecular weight was found to be 2190 bp, 2260 bp, 2275 bp and 2210 bp. RAPD analysis was performed to identify the level of genetic variation and polymorphism in P.excavates collected from four different locations. SDS-PAGE of vermiprotein of P.ceylanensis, which were grown in various substrates, showed several bands ranged from 37 to 250 kDa.


Day lighting is one of the important environmental factors that affect the health, emotions and academic performance of the students as well as the energy consumption of the educational buildings. These days it is obvious that designer must consider both the quantity and quality of the day lighting system of the building. In educational building windows are considered as the main fenestrations to provide proper daylight and natural ventilation. Daylight coming through the window depends on some internal variables (fenestration's size, shape, position on the wall, materials, colours, reflectance, transparency and space geometry). Besides these internal variables designer should consider some external environmental variables climate, sky condition, orientation of the building and orientation of window wall. In efficient daylight design these internal variables varies according to the external variables especially according to the orientation of the fenestration or window wall. During clear and partly cloudy conditions, each of the four cardinal orientations offers a light source that contrasts in both character and illuminance levels. But unfortunately daylighting haven't been designed well at most of the educational buildings in our country. Some prototype window having same size, shape, materials, shedding and control are used in same position in walls at any orientation. So, either glare or duskiness phenomenon is often happens in classrooms and dependency on artificial lighting is increased. This study examines the impact of lighting distribution of the same prototype windows in different wall orientation. This study also shows how different window's shapes, sizes, geometries and positions in different orientation respond to lighting distribution. This paper deals with light coming into the rooms through the window, where window is considered the only system to provide, control, and distribute light flux. ECOTECT and Radiance software are used to simulate the proposed window conditions. This study explores a new daylighting design method and process for educational building. This study can be used to build sustainable education buildings that are highly efficient with low running cost.


Calcineurin antagonists are known as potent immunosuppressants working particularly on T cells by virtue of their capacity to block nuclear factor of activated T cell (NFAT) activation and translocation to the nucleus. In addition to interleukin (IL)‐2 suppression, T helper cell type 1 (Th1) as well as Th2 cytokine transcription is blocked by calcineurin antagonists. Here, we show that calcineurin antagonists such as cyclosporin A (CsA) or tacrolimus can markedly enhance the production of interferon‐γ (IFN‐γ) by human T cells. This increased IFN‐γ production is dependent on T cell receptor (TCR) and CD28 signaling as well as on the presence of IL‐12. IL‐27, which could mimic the effect of IL‐12, was however less potent in inducing IFN‐γ production in the presence of CsA and TCR stimulation. Other cytokines such as IL‐23, IL‐18, IL‐2, or the Th2‐related cytokine IL‐4 are not able to support a calcineurin antagonist‐dependent up‐regulation of IFN‐γ. CsA‐dependent IFN‐γ production is observable in therapeutic concentrations. The effect is independent of IL‐10 or IL‐4, as addition of these cytokines could not inhibit the CsA‐induced IFN‐γ production. The effect of calcineurin antagonists is associated with an increased c‐fos expression and DNA‐binding activity of the transcription factor activated protein‐1 but not with increased DNA‐binding activity of T‐bet. Our study further supports the relevance of known calcineurin activities other than NFAT activation. The presented data may help to explain why concomitant infections (resulting in increased IL‐12 expression) under therapy with calcineurin antagonists often have a negative impact on the activity of the underlying disease (e.g., autoimmune disease).


This report shows highlights of ongoing or recently realised R&D, demonstration and deployment projects on geothermal energy in countries, participating in ERANET Geothermal energy. The projects are selected by the various agencies and research councils, because of their interesting impact on fundamental or practical knowledge about geothermal energy utilisation in their specific country.


To investigate the relationship between upper esophageal sphincter (UES) motility and globus sensation. Methods: UES motility was measured with Polygraf HR~(TM) Esophagus Manometry System in 22 patients with globus sensation (patients' group) and 25 healthy volunteers(volunteers' group). Results: UES length, UES resting pressure, UES relax pressure and UES relax rate of patients' group[(3.6±0.6) cm, (43.4±8.0)mm Hg, (0.3±0.8)mm Hg and 100%,respectively] were not significantly different with those of control group[(3.5±0.7)cm, (41.8±8.5)mm Hg, (0.4+0.9) mm Hg and 100%, respectively] ( P0.05, respectively). The coordinated motility of pharynx and UES was good. Conclusion: UES motility is normal in patients with globus sensation. There is no relation between UES function status and globus sensation.


In the post-gay liberation era, the body desirous of same-sex sex is presented with the possibility of existing without punishment. Indeed, gay liberation has demanded freedom for this body, insisting that the journey towards enlightened liberation must include a willingness on the part of the body to publicise all of its same-sex sexual desires and pleasures through proud articulation of "I am gay." This thesis attacks the assumption of freedom assigned within the discourse of gay liberation to both the act of sex and the act of speech. Specifically, I argue against the belief that the body is liberated when it and its pleasures are contained within an identified and identifiable (homo)sexual form. Within the poststructuralist and postmodern contexts, silence has been exposed as a means of repressing the truth. It seeks to deny marginalised bodies the freedom they crave and deserve. Such an interpretation of silence, however, is only one reading among many. I advocate a (re)turn to silence, a (re)casting of it as a mode of resistance to the discipline of the sex-truths established in the culture. In challenging the truths of "man" and "sex" through the construction of a Body without Sex (BwS), I dispute the reality of the homosexual type. The premise of this thesis is that the silence of a BwS offers a space in which the male-d body that engages in same-sex sexualised contact is able to resist the culture's dictate to be a homosexual. A silencing of anatomical sex and the act of sex disrupts compulsory homosexualisation. This thesis concludes with an application of the concept of a BwS to three male-male relationships in which the participants might experience mutual desires and/or corporeal pleasures. Here, with anticipated controversy, intimate unions between men and boys, "mates" and brothers are removed from the framework of compulsory sexualisation through which the culture demands they must be read. The intensity of the culture's focus on anatomical sex and the act of sex contain such relationships and the bodies involved within the discipline of the sexual. A BwS aims to resist such discipline through its desire to encourage the body and its pleasures to become other than signifiers of sexual truths.


Objective: To evaluate the association between D2 dopamine receptor gene -141C Ins/Del polymorphism and heroin dependence in Chinese Han population. 收稿日期(Date of reception):2014-09-12 第一作者(First author):胡佩武,Email: firstname.lastname@example.com 通信作者(Corresponding author):李杏莉,Email: email@example.com 基金项目(Foundation item):国家自然科学基金(81202257);中南大学教师研究基金(2013JSJJ032);教育部留学回国人员科研启动基金(第 47批)。Th is work was supported by the grants from the National Natural Science Foundation of China (81202257), Foundation of Central South University for Outstanding Young Teachers (2013JSJJ032); Scientifi c Research Foundation for the Returned Overseas Chinese Scholars, Ministry of Education, P. R. China (47th). DOI:10.11817/j.issn.1672-7347.2015.03.001 www.csumed.org/xbwk/fi leup/PDF/201503233.pdf ·ARTICLES· ·论 著· 中南大学学报 ( 医学版 ), 2015, 40(3) http://www.csumed.org 234 Methods: Chinese and foreign databases were searched for relevant articles published from the establishment of database to March 2014. Case-control studies on D2 dopamine receptor gene -141C Ins/Del polymorphism with heroin dependence in Chinese Han population were gathered with Meta-analysis by Stata 12.0 software after data abstraction. Results: Seven case-control studies on association between D2 dopamine receptor gene -141C Ins/ Del polymorphism and heroin dependence were included, which covered 3 211 heroin dependence patients and 1 979 controls. Meta-analysis results showed that the pooled odds ratio (OR), the 95% confidence interval (CI) and P value after combining genotypes were as follows: Ins/Ins vs Del/Del: OR=0.51, 95% CI: 0.27-0.96, P=0.017; Ins/Ins vs Ins/Del+Del/Del: OR=0.82, 95% CI: 0.72-0.94, P=0.448; Ins/Ins+ Ins/Del vs Del/Del: OR=0.53, 95% CI: 0.28-0.98, P=0.019; Ins/Del vs Del/Del: OR=0.59, 95% CI: 0.32-1.07, P=0.045; Ins vs Del: OR=0.79, 95% CI: 0.71-0.89, P=0.101). Conclusion: D2 dopamine receptor gene -141C Ins/Del polymorphism is associated with heroin dependence in Chinese Han population, and Chinese Han population with Ins allele gene deletion are at lower risk of heroin dependence.


In anxiety research, relative few psychophysiological studies have been conducted. In this chapter, we presented previous studies that used different psychophsiological markers that can be further utilized in future research. However, there are a few things to be considered when psychophysiological markers are used in anxiety studies, first of which may be genetic factors. Genetic factors influence vulnerability to anxiety disorders. There are several genetic polymorphisms associated with anxiety disorders among which are the serotonin-transporterlinked polymorphic region (5-HTTLPR), the Catechol-O-methyltransferase (COMT), and the brain-derive neurotrophic factor (BDNF) gene variants. We first presented studies that invsestigated the relationship between these genetics variants and anxiety disorders. Also, it has been suggested that anxiety disorders are characterized by abnormal neural activity— amygdala hyperactivity and dysfunctional prefrontal activity—and cognitive bias favoring threat-relevant stimuli (Cisler et al., 2010; McClure et al., 2007; Nitschke et al., 2009; Whalen et al., 2008). We will present different psychophysiological markers that have been used to study dysfunctional neural, serotonergic, cognitive and autonomic activites associated with anxiety disorders. They include: (1) a loudness dependence of the auditory evoked potential (LDAEP) which is proposed to be associated with serotonin activity, (2) various components of the event-related potentials [P1, P2, N300, P3b, early posterior negativity (EPN), late positive potential (LPP), and error-related negativity (ERN)] that reflect altered neural activity in anxiety disorders and (3) the reduced heart rate variability (HRV) which indicates autonomic dysregulation associated with increased sympathetic and decreased vagal control of the heart. Particularly, in this chapter, we introduced the loudness of the auditory evoked potential (LDAEP) as a possible psychophysiological marker that can be utilized in anxiety research. Our previous studies revealed that patients with different subtypes of anxiety disorders produced distinctive LDAEPs and that the LDAEP could play an important role in predicting the efficacy of selective serotonin reuptake inhibitor (SSRI) treatment in anxiety disorders (Park et al., 2010, 2011). We suggest that utilizing the LDAEP along with other various ERP components indicating neural and cognitive dysfunctions associated with anxiety disorders may enhance our understanding of the etiology and maintenance of anxiety disorders. Also, it is important to understand how they interact with each other and with other environmental stressor to reinforce or to exacerbate anxiety symptoms (see Figure 1). Of clinical relevance is whether these psychophysiological markers may play a role in predicting clinical outcome of different treatment.


Background: Large number of patient seek ENT consultation for central perforation of tympanic membrane. A significant portion of these cases are often found with very small central perforation. Minimyringoplasty is a very simple procedure to close such small perforations. Objective: the aim of the present study is to compare the surgical and audiological results of temporalis fascia versus more simple methods ( fat graft, fat graft wih hyaluronic acid and platelet rich plasma)in myringoplasty. Patient and Methods: a randomized prospective study concerned with 80 patients for whom myringoplasty was done. Patients were randomly assigned into four groups; in the first group fat graft was used (20patient) and fat graft with hyaluronic acid was used in the second group (20 patients).and platelet rich plasma was used in third group (20 patients) and temporalis fascia was used in fourth group (20 patients). Results: our study included 80 patients, 45 males and 35 females with a range from 18- 55 years. Surgical success rates75% , 80%, 75%and 75%for fat graft, fat graft with hyaluronic acid, platelet rich plasma and temporalis fascia respectively. There was 6.5 dB, 7db , 6 db and 5.5 db mean hearing improvement improvement in fat graft, fat graft with hyaluronic acid, platelet rich plasma and temporalis fascia respectively. Conclusions: The myringoplasty with fat graft,fat graft with hyaluronic acid and PRP is a minimally invasive effective procedure in management of the small central tympanic membrane perforations . Also it is safe and feasible procedure In this study we have achieved High success rate of repair of tympanic membrane perforation.


The invention relates to a method for producing a bituminous emulsion of using a primary bitumen emulsion, optionally diluted, characterized by a median diameter less than 2 microns, as the aqueous phase of a secondary emulsion of bitumen, characterized by median diameter greater than 2 microns, the final emulsion obtained is characterized by a bitumen content of 50% to 95% by mass, a STV viscosity at 40 ° C through the orifice of 4 mm lower than 300 s and a tendency to decantation measured by EN 12847 test less than 10%.


Fifty midges were collected by the staff of Qinhuangdao Entry-Exit Inspection and Quarantine Bureau at anchorage on 27 of 68 entry ships which came from Korea,India,Indonesia,Australia and Brazil et al.,from June to September,2003.These midges crawling up on the inner surface of ships windows,including 8 genera,Alluaudomyia,Atrichopogon,Bezzia,Culicoides,Dasyhelea,Forcipomyia,Lasiohelea.Palpomyia,were authenticated by classification.Among them 5 species of Culicoides,a species of Forcipomyia were named.And 2 species of Bezzia,containing a new species,Bezzia medusa Yu,Li et Nie,sp.nov.collected on an entry ship from Indonesia.


Through simulative test,this study screened out a few of food additives which could decrease the content of soluble fluorine in the leaves and soup of dark tea,including active calcium,magnesium chloride and active clay.These three additives could make the soluble fluorine content in tea soup decease to 44.0%,46.3% and 54.6% of that in the original tea soup,respectively;when they were directly mixed with dry dark tea,the soluble fluorine content in tea could be deceased to 64.4%,71.1% and 73.2% of that in the original tea,respectively.Thus it is inferred that food additives can decrease the content of soluble fluorine in dark tea when they are properly used.


Modern education should transform from examination education into quality education in order to adjust to the growth of the times. Since College English teaching is an indispensable part of quality education, as its important resources,College English textbooks need to be updated. Emerging as the times demand, the serial textbooks published by Nanjing University Press break away from the knowledge-centered proneness, and attach great importance to the organic integration of the learning of language knowledge and the cultivating of integrative quality, and thus ensure the successful transformation of quality education in College English teaching.


N ~ G ~ E ' s pelvis is an uncommon &foriliac crest reached a higher level than its fellow, and mity which may easily be overlooked if the vulva and pubic arch were directed towards the antenatal examinations are in a left side. A slightly limping gait was noticed. An X-ray film (Fig. I), taken to determine the perfunctory way* The report is degree of the resulting deformity of the pelvis, a reminder Of the need to gauge illustrates the changes characteristic of an obliquely the Of the even when deformed pelvis of Naegele type. The left sacral fie routine pelvic measurements are ala is incompletely developed, and the foramina normal. on that side are small. There is bony fusion of the sacrum and ilium on the left side, the left iliopectineal line is straightened, and the left ischial A Chinese woman, aged 22, 2-para, first attended tuberosity and spine are displaced inwards and the antenatal clinic on 2nd April, 1948, a t the 36th upwards. There is a severe encroachment on the week of pregnancy. She gave a history of a difficult area of the pelvic inlet and cavity available for the labour a t her k s t delivery, 18 months previously. transmission of the foetal head. This had been a t term, and after she had been in In view of the history and physical signs, labour for 2 days, a difficult forceps extraction was Caesarean section was advised, and a date appointed performed which " required the force of z persons," for it one week before the expected date of confineand resulted in the delivery of a dead baby with ment. The patient did not report to hospital on lacerated scalp and fractured skull. this date, and z days later the hospital almoner, On examination the routine measurements of the visiting her in her home, found that she had already pelvis were found to be within normal limits for been in labour for some hours. She was persuaded North Chinese women (interspinous, 20.5 cm.; to return to hospital, and a lower segment Caesarean intercristal, 22 cm.; external conjugate, 17.5 cm.; section was begun as soon as preparations for -intertuberous, 8.0 cm.); but a general inspection operation had been completed. By this time she of the pelvis revealed scarring of the skin over the had been in labour for 10 hours, and was having left sacro-iliac joint. The patient then disclosed continuous severe uterine contractions, which that at the age of 3 years, she had been confined caused her great pain. The foetal head showed no to bed for I year with a disease, presumably sign of entering the pelvis. At operation, under chronic inflammatory sacro-iliac, joint disease, spinal analgesia, there was no difficulty in deliverwhich resulted in discharging sinuses and subseing the foetal head, which was still not engaged a t quent scarring. the brim. The child weighed 3,700 g.; the circumWith the patient standing in the erect position, ference of its head measured 35 cm., and both some pelvic asymmetry was noticeable. The left mother and child did well. CASE REPORT.


LL. D., Professor of the Diseases of the Mind and Nervous System, and of Medical Jurisprudence, Missouri Medical College, St. Louis ; late Physician-in-Chief to St. Vincent's Institution for the Insane ; Corresponding Member of the New York Society of Neurology and Electrology ; formerly Consulting Physician of the St. Louis County Lunatic Asylum ; Member of the New York Medico-Legal Society, etc. Second edition. Philadelphia : J. B. Lippincott Co. 1892.


Demands placed on teachers and students continue to increase in order to develop the skills required of the 21 century workforce. There continues to be a need to utilize curriculum and instruction to inspire students to engage in STEM majors and careers. Improving instructional methods and providing opportunities for students to question and problem solve, through the use of inquiry-based instruction (IBI) can increase scientific reasoning abilities. This instructional approach may assist in improving, not only the academic achievement of students, but it may encourage students to plan to attend college and develop potential career aspirations for agriculture and STEM. This research used the scientific reasoning scores from 663 students enrolled nationwide in school-based agricultural education programs (SBAE) to predict students' likelihood to indicate plans to pursue a career in agriculture, STEM or plan to attend college. The findings reveal scientific reasoning scores predict students' likelihood to indicate intention to pursue a STEM career and plan to pursue college. Implications from this research suggest SBAE instructors should continue their efforts to incorporate IBI into instruction in order to engage students to think critically and solve real world problems, while exposing students to the skills requisite for STEM major/career access.


Epoxidation of propylene into propylene oxide (PO) in gas phase is a highly challenging reaction. Cu based catalysts have been active for this reaction, but, the state of Cu as active species is st...


A randomized algorithm for deciding whether two positive integers, represented succinctly by arithmetic circuits, are equal or not. If we are given two positive integers written in binary, then it is obviously very easy for us to decide whether the two integers are equal or not. However, if instead we are given two positive integers represented succinctly, using arithmetic circuits, deciding whether they are equal or not is a much more challenging task. In this tutorial you will be asks to devise a randomize polynomial time algorithm for this task and, importantly, to prove its correctness. An arithmetic circuit, or equivalently a straight-line program, C, with m arithmetic gates, restricted to addition or multiplication gates only, and using only the input value 1, is defined by a sequence of arithmetic instructions of the following form:


The p53 tumor suppressor is a transcriptional factor that controls a network of cellular processes essential for the maintenance of genomic integrity and prevention of malignant transformation. Ironically, p53 was initially described as an oncogene, and it took quite some time to realize that the protein found in tumors was a mutated version. Mutations in the TP53 gene are the most frequent genetic alterations detected in human cancers. In contrast to other tumor suppressors that are usually inactivated by frame-shift or nonsense mutations, the majority of cancer-associated TP53 mutations are non-synonymous missense substitutions, which indicate that cancer cells can benefit from the presence of mutated p53 protein with compromised functions (loss of function – LOF). Furthermore, some common TP53 missense mutations possess gain-of-function (GOF) properties that furnish mutant protein with new oncogenic qualities. A plethora of mutations detected in the TP53 gene, which gives rise to more than 2000 different protein variants, makes the issue very complex, but the progress in experimental and data mining methods provided significant advances in understanding functional consequences of different p53 mutations. In this Research Topic, a few excellent reviews summarize the latest achievements in this field. Zhu et al. outline the spectrum of tumorigenic activities displayed by mutant p53 and discuss different therapeutic strategies to target cancer with TP53 mutations. The key targeted approaches – small molecule reactivators, gene editing, and immunotherapy aimed at mutant p53 tumors are also the topic of the review by Chasov et al. The work of Alvarado-Ortiz et al. is focused on the molecular mechanisms underlying the oncogenic activity of GOF p53 mutants. Based on the recent publications they analyze the role of p53 GOF mutations in metastasis, immune escape, metabolic reprogramming, cancer cell plasticity, and therapy resistance, and consider therapeutic perspectives. Metabolic functions of mutant p53 are particularly addressed by Etichetti et al. The authors recap current evidences for the role of mutant p53 in alteration of the mevalonate pathway and its contribution to enhanced prenylation of oncogenic proteins via positive regulation of Isoprenylcysteine Carboxyl Methyltransferase (ICMT). The interplay between mutant p53 and mevalonate pathway is further addressed in the research of Romeo et al. They explore how inhibition of STAT3 affects the mevalonate pathway and influences the expression of HSP90. The authors provide data arguing for the role of STAT3 in the stabilization of mutant p53 protein. On the other hand, it is known that in colorectal cancer the GOF hot-spot p53 mutants can


s he begins his commentary on the fourth book of the Aeneid, Servius declares the entire book to be derived from Apollonius' depiction of Medea in love in the third book of the Argonautica: Apollonius Argonautica scripsit et in tertio inducit amantem Medeam: inde totus hic liber translatus est.1 While the makeup of Dido's character is one of the most complex in the poem (it alludes to, among others, Nausicaa, Ariadne, and Cleopatra2), Medea may be the most powerful and sustained presence. Two Medeas are evoked in Vergil's depiction of his heroine. Encouraged by Venus and Juno to fall in love with the handsome stranger who needs her help to continue on his quest, Dido is likened to the young Medea of Apollonius. In the bitter exchange of speeches with Aeneas, and her turn to magic in despair, she is linked to the older, aggrieved Medea of Euripides.3 But there are echoes in the poem that point to another young princess, similar in many ways to the young Medea of Apollonius, but tragically connected to the destructive Medea of Euripides.4 My goal is to explore Dido's relationship to the Corinthian princess who burns and melts by Medea's design in Euripides' play. I will argue that this additional Euripidean connection complicates the allusions to Medea and sheds new light on two important episodes, the gift-giving scene in Book 1 and Dido's suicide in Book 4.5 I will also show that, once initiated through the character of Dido, the presence of the princess contributes to the allusive makeup of other characters, especially Creusa and Lavinia, who are connected to each other and to Dido within the poem through their relationship to Aeneas.


A novel audio watermarking algorithm based on neural networks was proposed. By transforming original audio sequence into 1D wavelet domain and selecting proper positions, several watermark bits were embed. Before transmitting, it effectively utilizes neural networks to learn the relation characteristics between original audio and watermarked audio. Due to the learning and adaptive capabilities of neural networks possessing, the trained neural networks almost exactly extract the watermark from the watermarked audio against audio processing attacks. Extensive experimental results show that the proposed method significantly possesses robustness. It is immune against such attacks as low pass filtering, addition of noise, resampling and medium filtering.


The invention discloses a rate gyroscope-based flexible antenna servo control system. In the system, a rate gyroscope is introduced to extract the speed of a flexible antenna electrical shaft during movement and change a control structure of a servo system, so that the system can directly control the antenna electrical shaft, but does not only control an antenna mounting base; therefore, the problems of rapidity and stableness of the flexible antenna servo system are solved well; and the rate gyroscope, an antenna base angle measurement device and an antenna speed feedback controller are introduced to sense and control the rate of the flexible antenna electrical shaft, so that the system becomes a fully-closed loop control system for the flexible antenna electrical shaft, and the positionof a flexible antenna is heightened, or the speed control performance of the flexible antenna is improved. In the system, an accurate mathematical model of the antenna is not required to be known; and the control system is extremely convenient to design and debug and has extremely high practical value.


Abstract We propose a new method for measuring transient radiation effects in optical fibers on a nanosecond time scale. The method, which incorporates a streak camera, allows more precise time resolution than other methods and has the advantage of simultaneously measuring radiation-induced attenuation as a function of wavelength and time. By choosing different light sources and sweep speeds, radiation-induced attenuation may be measured in a variety of experimental configurations. Examples are given of the types of output obtained with this method. In addition, we discuss possible mechanisms for radiation-induced darkening.


The last philatelic issue made by the Romanian postal administration in collaboration with WWF, published at the end of 2006, is the main subject of this study. As we have become accustomed to, WWF's interests in conserving endangered species are becoming better defined. This time the emphasis is on protecting birds, and among these, we are talking about the Eurasian spoonbill. The species itself is representative of the habitat of the Danube Delta, where it was also immortalized, and where the inspiration for the layout of the philatelic pieces came from. Moreover, through the rich philatelic material identified, analyzed, and presented, one can discuss the other philatelic effects. All these, through the beauty of the exhibition and the contribution brought among the collectors, philatelists, and implicitly of those who love nature, make the issue a successful one. The purpose of this study is to complete, by presenting the philatelic issue from 2006, the series of Romanian philatelic issues dedicated to the protection of various species. In this regard, besides the well-defined role in promoting protected species, was also discussed a little about the role of philately in educating the young generation, informing tourists, as well as in documenting habitat conservation policies and strategies.


In the direct torque control (DTC) of Interior Permanent-Magnet Synchronous Machine (IPMSM), the machine inductances are used to compute electromagnetic torque and stator flux. However, the inductances of machine vary nonlinearly with respect to the current due to magnetic saturation effect. To online estimate the inductances of an IPMSM, this paper proposes a novel method based on the current response caused by active voltage vectors inherent in DTC. There is no need to introduce other current injection signal. In addition, other machine parameters, such as winding resistance and rotor flux, are not required to online estimate machine inductance. The influence of magnetic saturation on the performance of the inductance estimator is also investigated. Simulation results verify the effectiveness of the proposed geometrical method in online estimation of inductance when taking magnetic saturation effect into account.


Traditional charge pumping (CP) technique relies on trap-assisted recombination from the source/drain to the body contact to characterize interface trap density (<inline-formula> <tex-math notation="LaTeX">${N}_{\text {it}}$ </tex-math></inline-formula>) of classical bulk MOSFETs. A variant of the technique called single pulse CP (SPCP) allows interface trap characterization even if the bulk contact is absent, as in silicon-on-insulator (SOI) MOSFET. Unfortunately, neither technique is useful for devices with source-body-tied (SBT) and inhomogeneous channel doping profile, as in lateral diffused MOS (LDMOS) power transistors. Here, we propose a generalization of the CP/SPCP techniques, called Super SPCP (<inline-formula> <tex-math notation="LaTeX">$\text{S}^{{2}}$ </tex-math></inline-formula>PCP), to extract position-resolved localized degradations (<inline-formula> <tex-math notation="LaTeX">${\Delta {N}}_{\text {it}}$ </tex-math></inline-formula>) in an SBT LDMOS. Careful TCAD modeling and experimental characterizations demonstrate the effectiveness of the proposed approach. Our analysis provides deep insights into the physics of the SPCP technique, demonstrating that the approach can be used to characterize a variety of transistors with nontraditional doping profiles and contact configurations.


Background: Cervical cancer or commonly known as cervical cancer is one of the biggest causes of death for women, at least every year worldwide more than 270,000 deaths occurred due to cervical cancer. IVA test examination is an examination of alternative screening pap smear because it is cheaper, practical, very easy to implement and simple equipment and can be done by health personnel such as midwives in addition to obstetricians gynecology. Destination: Conduct reproductive health services for women. Methods: Descriptive by describing the course of the process of community service. Results: Community paralegals IVA test examination were 44 respondents. This examination was conducted over two days on July 30 and August 6, 2015. The age of respondents who follow IVA test that is 11.4% of 20-29 years, 30-39 years 34%, 40-49 years 27.3%, 50-59 years 25%, 60-69 years 2.3%. The use of condoms contraception 2.3%, 2.3% pills, injections 3 months 27.3%, IUD 4.5%, 9.1% Implant, MOW 15.9%, 38.6% and without planning. IVA examination results that from 44 respondents, 4 respondents with positive results IVA, and 40 respondents negatively. Then the results obtained inspekulo 26 respondents experienced erosion and 18 respondents did not experience erosion. Keywords: IVA Test, Paralegal


'Tis said, to know others is to be learned, to know oneself, wise - I demonstrate that it could be more fundamental than knowing the rest of nature, by applying classical computational principles and engineering hindsight to derive and explain quantum entanglement, state space formalism and the statistical nature of quantum mechanics. I show that an entangled photon pair is literally no more than a 1-bit hologram, that the quantum state formalism is completely derivable from general considerations of representation of physical information, and that both the probabilistic aspects of quantum theory and the constancy of h are exactly predicted by the thermodynamics of representation, without precluding a fundamental, relative difference in spatial scale between non-colocated observers, leading to logical foundations of relativity and cosmology that show the current thinking in that field to be simplistic and erroneous.


Traditional syringe is using the stainless steel needles to inject the human body, this injection will not only cause pain, but will also cause bleeding in the skin, there is a potential risk of infection, in order to avoid the use of safe risk, needle free injection technology has been the international research hotspot in this field. The important technology of needle free injection is how to achieve drugs jet importing, which need strong drive-force and fast response power systems, so that pulse force will improve the piston of closed drug container to produce transient high pressure to force drugs extruded from micro hole, to form a high-speed jet micro fluidizer, that will penetrate rapidly the skin of the human or animal body to reach the drug absorption best parts. The existing power system is can be roughly divided into three types technically: compressed gas, fuel and hard spring. Traditional compressed gas law need to be equipped with a high-pressure gas storage and air compression device, which is bulky, expensive, energy-intensive and time-consuming, so it is very inconvenient to use. Similar with rocket technology, detonation fuel can provide enough thrust powerful to generate shock waves, but potentially dangerous and unstable factors are indeed worrying. Hard spring as power system is simpler than the above two kind of method, but it is a little difficult to operate. As a solution, adding the effect of permanent magnetic damping, a pneumatic needle free syringe successfully designed with high efficiency, low labor intensity, easy to operate, a slight noise, and adjustable injection force, which is facilitate to the use of clinical staff, and has a very good market prospects.


Objective—This study determined the role of angiotensin-converting enzyme (ACE) on the development of angiotensin I–induced atherosclerosis and the contribution of leukocyte-specific expression of this enzyme. Approach and Results—To define the contribution of ACE-dependent activity to angiotensin II synthesis in atherosclerotic development, male low-density lipoprotein receptor−/− mice were fed a fat-enriched diet and infused with either angiotensin I or angiotensin II. The same infusion rate of these peptides had equivalent effects on atherosclerotic development. Coinfusion of an ACE inhibitor, enalapril, ablated angiotensin I–augmented atherosclerosis but had no effect on angiotensin II–induced lesion development. ACE protein was detected in several cell types in atherosclerotic lesions, with a predominance in macrophages. This cell type secreted angiotensin II, which was ablated by ACE inhibition. To study whether leukocyte ACE contributed to atherosclerosis, irradiated male low-density lipoprotein receptor−/− mice were repopulated with bone marrow–derived cells from either ACE+/+ or ACE−/− mice and fed the fat-enriched diet for 12 weeks. Chimeric mice with ACE deficiency in bone marrow–derived cells had modestly reduced atherosclerotic lesions in aortic arches but had no effects in aortic roots. Conclusions—ACE mediates angiotensin I–induced atherosclerosis, and ACE expression in leukocytes modestly contributes to atherosclerotic development in hypercholesterolemic mice.


Using first-principles modeling, we investigate how phonon transport evolves in layered/van der Waals materials when going from 3D to 2D, or vice versa, by gradually pulling apart the atomic layers in graphite to form graphene. Focus is placed on identifying the features impacting thermal conductivity that are likely shared with other layered materials. The thermal conductivity $\kappa$ of graphite is found to be lower than that of graphene mainly due to changes in the phonon dispersion driven by van der Waals coupling. Specifically, as the atomic layers are brought closer together, the acoustic flexural phonons in graphene form low-energy optical flexural phonons in graphite that possess lower in-plane velocities, density-of-states and phonon occupation, thus reducing $\kappa$. Similar dispersion changes, and impact on thermal conductivity, can be expected in other van der Waals materials when transitioning from 2D to 3D. Our findings also indicate that the selection rules in graphene, which reduce phonon-phonon scattering and contribute to its large $\kappa$, effectively hold as the atomic layers are brought together to form graphite. While the selection rules do not strictly apply to graphite, in practice similar scattering behavior is displayed due in part to the weak inter-layer coupling. This suggests that van der Waals materials, in bulk 3D form, may have lower phonon-phonon scattering rates than other non-layered bulk materials.


Tests were performed to evaluate whether a metered mixing system can mix PR-1221 polysulfide adhesive as well as or better than batch-mixed adhesive; also, to evaluate the quality of meter-mixed PR-1860 and PS-875 polysulfide adhesives. These adhesives are candidate replacements for PR-1221 which will not be manufactured in the future. The following material properties were evaluated: peel strength, specific gravity and adhesive components of mixed adhesives, Shore A hardness, tensile adhesion strength, and flow rate. Finally, a visual test called the butterfly test was performed to observe for bubbles and unmixed adhesive. The results of these tests are reported and discussed.


This paper reports the cooling performance and thermal characteristics of a GdBCO magnet cooled by a mixed cryogen cooling system employing a mixture of solid nitrogen and a small amount of liquid neon. The test magnet, composed of four sets of no-insulation (NI) GdBCO double-pancake racetrack coils, was designed to have enhanced magnet stability. During cooldown to the operating temperature of 26 K, the temperature difference within the magnet was less than ~0.5 K, an indication that the cooling performance was excellent due to the presence of solid nitrogen coupled with a large heat capacity. In repetitive heating tests at 26 K, the peak temperatures of the magnet when cooled by the mixed cryogen were much lower than when cooled by solid nitrogen alone. This was because liquid neon in the mixed cryogen serves as an effective heat exchanger and enhances the heat transfer between the magnet and the solid nitrogen. During charge testing, the magnet could successfully generate the target center field of 2 T at the operating current of 130 A. The test results demonstrated the feasibility of the NI GdBCO magnet in a mixed cryogen cooling system for the development of reliable next-generation portable superconducting applications.


Shrimp aquaculture industry has shown immense good growth in last decades. Black tiger shrimp (Penaeus monodon) and the white leg Pacific shrimp (Litopenaeus vannamei) are the main contributor in the shrimp culture production. India ranks first in shrimp products export due to great development in shrimp farming. Shrimp farming has been also developing actively in India and Gujarat. Presently Gujarat is producing 55,161 tons of high quality shrimp from 7542 ha. The present study was carried out at shrimp farms of six districts of Gujarat viz., Gir-somnath, Amreli, Bhavnagar, Surat, Navsari, Valsad during the year 2018 to assess the pond production of shrimp culture pond. Five ponds from each selected districts was randomly selected. The data were collected during March to September 2018. The growth parameters viz., weight gain, Feed Conversion Ratio (FCR), Average Daily Gain (ADG) and survival percentage were calculated. Stocking density, harvest size, FCR, culture period, ADG of selected district were significantly different (P<0.01) while pond production and survival percentage of selected district were not significantly different (P<0.01) Water parameters were significantly different (P<0.01) accept alkalinity which is not significantly different among all the ponds. To sustain the present culture practices in Gujarat, it is being recommended to adopt better management practices. The study has also provided essential information on which further studies can be carried out to evaluate impact of water parameters on growth & survival and also supports protection and decision making for sustainable development in the coastal districts of Gujarat.


1589 Background: In 2018, federal regulations expanded access to short-term limited duration insurance (STLD) plans. STLD plans generally limit coverage of medical services and have no cost-sharing caps, which can delay a cancer diagnosis. Furthermore, uptake of STLD plans can destabilize individual insurance markets, leading to increased prices and subsequent barriers to care for comprehensive insurance plan enrollees. Several states introduced legislation prohibiting and/or limiting STLD plans, but it is unclear whether STLD plans or policies restricting their proliferation have affected cancer stage at diagnosis. Methods: Individuals ages 18-64 years with staged first primary malignancies diagnosed 2016-2019 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Difference-in-differences (DID) analyses evaluated changes in early-stage (stages 0 [breast and bladder only] through II) diagnoses from pre- (2016-2017) to post- STLD expansion (2019; 2018 was excluded as washout/phase-in period) between states with policies prohibiting and/or limiting STLD plans vs. states with no policies regulating STLD plans. In some states limiting but not prohibiting STLD plans, insurers stopped selling STLD plans; we conducted additional analyses by state STLD plan availability in 2019. Linear probability models utilized cluster-robust standard errors (clustered at state level) and adjusted for fixed state and year effects, sociodemographic covariates, and cancer site. Sensitivity analyses excluded states that expanded and/or substantially changed Medicaid eligibility during the study period. The plausibility of the parallel trends assumption was tested in adjusted models restricted to the pre-policy period (2016-2017) and was satisfied for all analyses. Results: 398,190 individuals were included. In adjusted DID analyses, early-stage diagnoses increased 0.95 percentage points (95% CI = 0.53 to 1.38, p<.001) in states that prohibited vs. did not regulate STLD plans, but there was no relative change in early-stage diagnoses in states with other policies limiting STLD plans (p=.25). Relative to states where STLD plans remained available, there was a nonsignificant increase in early-stage diagnoses in states where legislation stopped the sale of STLD plans, with greater evidence for an increase after excluding states with Medicaid eligibility changes (1.03, 95% CI = 0.71 to 1.35, p<.001). There were no differential changes in early-stage diagnoses by state group in falsification tests limited to individuals >65 years-old, who were Medicare-age-eligible. Conclusions: State legislation prohibiting and/or leading to the cessation of STLD plans was associated with an increased rate of early-stage cancer diagnoses. Alternatively, the proliferation of STLD plans was associated with a differential decreased rate of early-stage cancers.


The increasing consumer's demand for high quality and healthier foods is drawing a great attention on milk fatty acid (FA) composition. However, the inclusion of these traits as breeding goals in traditional selection plans is hampered by cost and logistic problems. Medium infrared spectroscopy (MIR) is a valid and cheap alternative to the traditional laboratory gas chromatography (GC) methodology for predicting milk fatty acids composition. Moreover, genomic selection (GS) could represent a valid option for breeding for these traits. Objective of this research was to estimate breeding values for milk FA composition in dairy sheep using two different phenotypes (GC vs MIR) and two breeding strategies (traditional vs GS). Milk FA composition, pedigree relationships, and SNP genotypes were available for 769 Sarda breed ewes, divided in two groups: 669 in training and 100 validation cohorts, respectively. Traditional EBV were estimated using a BLUP animal model whereas GEBV were estimated using a single step approach. Prediction accuracies for validation animals were rather low (<0.30), but always higher for GEBV in comparison with EBV. Moreover, no differences were observed between GC and MIR phenotypes.


It is desirable to develop large complex systems using components based on systematic abstraction and composition. Our goal is to develop a compositional real-time scheduling framework to support abstraction and composition techniques for real-time aspects of components. In this paper, we present a formal description of compositional real-time scheduling problems, which are the component abstraction and composition problems. We identify issues that need be addressed by solutions and provide our framework for the solutions, which is based on the periodic interface. Specifically, we introduce the periodic resource model to characterize resource allocations provided to a single component. We present exact schedulability conditions for the standard Liu and Layland periodic task model and the proposed periodic resource model under EDF and RM scheduling, and we show that the component abstraction and composition problems can be addressed with periodic interfaces through the exact schedulability conditions. We also provide the utilization bounds of a periodic task set over the periodic resource model and the abstraction bounds of periodic interfaces for a periodic task set under EDF and RM scheduling. We finally present the analytical bounds of overheads that our solution incurs in terms of resource utilization increase and evaluate the overheads through simulations.


Protein aggregation is a sophisticated biological mechanism that can have detrimental consequences. It is recognized as the hallmark of neurodegenerative diseases, suffered by millions of people each year reported by World Health Organization, [Formula: see text]. Abnormal deposits of amyloid fibrils and/or oligomers accumulate in and around neurons causing irreparable damage that leads to severe deterioration of the surrounding brain tissue and cognitive function. As of now, early detection, therapeutic intervention and treatment options are extremely limited. Protein aggregation is known to be highly dynamic, irreversible process which is source of its difficulty to fully understand and remedy the problem. The design of our study is to interpret the mechanics of intrinsically disordered proteins that self-assemble into highly structured fibrils. The aim is to gain a deeper understanding of protein–protein interactions, environmental conditions and chaperone failure that attribute to the aggregation process. The complexity of the aggregation process cannot be modeled using statistical physics and statistical thermodynamics of equilibrium processes. There are numerous studies that suggest protein aggregation which is a non-equilibrium process. Based on non-equilibrium physics, one of the best ways to understand it is through the Langevin and Fokker–Planck equations. Langevin equations describe stochastic dynamics of non-equilibrium processes. The Fokker–Planck equation is used to calculate the probability distribution and explain the trend in entropy of a model independent protein aggregation process.


The American Public Transportation Association's (APTA) Passenger Railroad Equipment Safety Standard (PRESS) Task Force initiated a testing program to develop a new railroad vehicle glazing standard. The program was coordinated and funded through the Federal Railroad Administration (FRA). This paper presents the procedures and results of this testing program. The test program used an air cannon to project various sizes of steel balls at speeds between 30 and 125 miles per hour and a 24-pound cinder block at 30 miles per hour to impact different glazing samples (glass laminates and polycarbonates) in the vertical position with the impactors striking at 90 degrees to the samples. With the cinder block, the impacts had to occur between the corner of the block and the samples. A pendulum system was used to impact the samples at slower speeds. The ballistic tests consisted of a 0.22-caliber long rifle, 40-grain bullet at speeds between 960 and 1163 feet per second. The pass/fail criteria were dislodgment of the glazing from the frame, or spall penetrating one mil aluminum foil witness plate placed 6 inches behind the samples. Based on this test program and input from the rail industries, a new glazing standard was developed.


This work is motivated by the need to develop accurate models for chemically reacting compressible turbulent flow fields that are present in a typical supersonic combustion ramjet (SCRAMJET) engine. In this paper the development of a new assumed probability density function (PDF) reaction model for supersonic turbulent diffusion flames and its implementation into an efficient Navier-Stokes solver are discussed. The application of this model to a supersonic hydrogen-air flame will be considered.


A speech delivered by Peter Tomasetti SC describing the Bar's charitable activity is presented. He spoke about the $65,000 donation of the Silks of 2007 to the Indigenous Literacy Project, aimed at improving literacy among Aboriginal people.


1. Becoming a subject leader: Roles, values and accountability 2. Leading effective teaching and learning 3. Leading and managing staff 4. The strategic direction and development of a department: Leadership, planning, performance and the use of ICT 5. The efficient and effective deployment of staff and resources 6. Managing your own performance and development.


In this paper, we present one generalization of the famous capacitated p-median location problem, called budget constraint multi-capacitated location problem (MCLP). This generalization is characterized by allowing each facility to be used with different capacity levels. We consider n customers, m facilities and l capacity levels, we note that the solution shape of MCLP can be represented as a set of disjoint clusters, each cluster is composed of one facility and a subset of customers. When creating clusters, some constraints must be met, namely the level selection and capacity. In this work, we present the new formulation of the MCLP based on set partitioning, then we suggest an adapted solving method, which will be called NFF (Nearest Facility First). The NFF approach is used in two ways: as a heuristic by taking only the first solution found or exact method when waiting finish the execution. Computational results are presented at the end using instances that we have created under some criteria of difficulties or adapted from those of p-median problems available in literature. The NFF method provides very good results for low and medium difficulty instances, but it is less effective for the more complex ones. To remedy this problem, the method will be supplemented by column generation approach.


Objective To investigate the distributions of the known SNPs of EVI5 and LDLRAP1 genes in Chinese patients with coronary heart disease(CHD) and non-CHD people in Guangdong area by PCR,and to analyze the correlations between these SNPs and CHD.Methods Blood samples from 143 cases of CHD diagnosed by coronary angiography and 79 cases of non-CHD were collected.Genomic DNA was amplified by PCR and verified by DNA sequencing.Results There was no significant difference in allele or genotype frequency between the CHD and non-CHD individuals(P0.05).Conclusion The rs7515577 polymorphism of the EVI5 gene or the rs12027135 polymorphism of the LDLRAP1 gene is not correlated with CHD.


Proceedings of Council p. 57 Correspondence: The Inurance Medical Service Week by Week 63 The Future of Medical Practice. W. Guyon Richards, Naval, Military, and Air Force Appointments 65 M.B.; John A. McCluskie, M.B. p. 64 Association Intelligence, Diary, and Notices 66 Maternity Services (Scotland) Act. W. Hamilton, M.B. 65 Postgraduate Courses and Lectures66 Insurance Company Medical Certificates. Chas. E. S. Postgraduate News and Diary 67 Flemming -65 Diary of Societies and Lectures67 Vacancies-63


The study of behavioural phenotypes could be said to go back to the days of the syndrome first described by Down.1 He believed that affected children (whose genetic anomaly was of course not known to him) had distinctive personality characteristics, including "a lively sense of the ridiculous", among others. Subsequent studies have failed to confirm these stereotypes.2 Nevertheless, there have since been numerous attempts to discover, among individuals with known chromosomal or genetic anomalies, mental features that are causally related to the underlying condition. Opinions are divided, between those who regard the study of behavioural phenotypes as being worthwhile3and those who have their doubts.4 Before discussing the arguments, a definition is required.

There is no consensus. Flint2 suggested that it is: "a behaviour, including cognitive processes and social interaction style, that is consistently associated with, and specific to, a syndrome which has a chromosomal or a genetic aetiology". He added "where there is little doubt that the phenotype is a consequence of the underlying anomaly", but others feel that definition is too restrictive.5 6 In practice, most behavioural phenotypes are associated with chromosomal aneuploides and microdeletions rather than point mutations in a single gene.

The study of behavioural phenotypes aims to identify bona fide links between genotype and phenotype. A few moments' reflection only is necessary to realise that there are many problems with the concept. First, is the term to be restricted only to disorders in which a genetic anomaly has been identified? There are many conditions (such as Rett syndrome7) that appear to have a genetic origin and characteristic behavioural features, but the nature of the genetic deficit is not known. Second, is it likely that any cognitive or behavioural features will be found consistently, unless they are part of …


Herein, the strain‐rate sensitive deformation behavior of a sintered Al‐ and Mo‐modified CrFeCoNi high‐entropy alloy (HEA) is focused. The sintered microstructure is investigated using scanning electron microscopy (SEM), electron backscatter diffraction (EBSD), energy‐dispersive X‐ray spectroscopy (EDS), and X‐ray diffraction. It was found that after sintering, the microstructure is of very low porosity (<1%) and consists of an ultrafine Mo‐ and Cr‐rich σ phase embedded in a fine‐grained face‐centered cubic (FCC) matrix. Electron microscopy reveals another secondary phase in which Al and Ni are concentrated. For a detailed discussion of the deformation behavior under tension and compression, tensile and compression tests were conducted at strain rates of 10−3, 10, and 102 s−1. Strain‐rate sensitive deformation behavior in terms of strength is observed. The strain hardening rates show no significant strain rate sensitivity (SRS) up to strain rates of 10 s−1. However, at higher strain rates and under compressive loading, a distinctly increased strain hardening rate is found. Tension/compression asymmetry is determined since the SRS value m is twice as high under compression than under tension.


Scholars of social movements tend to regard professionals as a homogeneous group whose activism plays a secondary role in mobilization processes. In this article, I focus on activism driven by professionals themselves and therein examine how heterogeneous professionals participate in their activism. Drawing on the case of the Guantanamo habeas lawyers, I utilize a two-step methodology to investigate the factors that contribute to the differential participation of legal professionals. The first stage of analysis shows that while lawyers with higher status played a critical role in initiating professional activism under a hostile environment, the Rasul v. Bush ruling opened up a legal opportunity for lawyers with lower status to participate in activism. In the second stage, social network analyses of the lawyers' collaborative structure reveal that movement-affiliated lawyers played a bridging role that coordinated initiators and latecomers. The results have important implications for understanding professi...


The authors of this paper adapted and/or improved several components of published behavioral treatment protocols for recurrent abdominal pain (RAP) and compared them using a pretestposttest control group design. Participants in this research were 64 children and adolescents (mean age, 9.75 yr, SD = 2.46) with diagnosed recurrent abdominal pain. They were randomly assigned to 4 groups: (1) fiber-only comparison group; (2) fiber and biofeedback-assisted cultivated low arousal; (3) fiber, biofeedback, and cognitive-behavioral interventions; and (4) fiber, biofeedback, cognitive-behavioral, and parental support. Treatment was provided over 8 weeks in individual sessions. Biofeedback was supplied using small thermal devices. The results revealed that all groups showed improvement in self-reported pain. The active treatment groups, however, showed significantly more improvement than the fiber-only comparison group (fiber only pain reduction = 79%; fiber and biofeedback = 100%; fiber, biofeedback, cognitive-behavioral = 94%; fiber, biofeedback, cognitive-behavioral, and parental support = 93%). Because the addition of cognitive-behavioral and parental support components did not seem to increase treatment effectiveness, the authors conclude that increased fiber with biofeedback-assisted cultivated low arousal was effective and efficient as a treatment modality for RAP.


Ruthenium(II) and osmium(II) complexes [MCl(LL)2]Y, where LL is 1,3-bis(diphenylphosphino)propane or 1-diphenylphosphino-2-(2′-pyridyl)ethane, promote the oxidation of a number of alkenes by PhIO, hypochlorites, and H2O2.


In the electric motor/generator arrangement described in the specification, a hollow cylindrical generator rotor is mounted on an input shaft connected to an internal com bustion engine and a hollow cylindrical electric motor rotor is connected to an output shaft. Both rotors have circum ferential rings of permanent magnets of alternately opposite polarity, and the rings are disposed in axially-spaced rela tion. A stator has at least one switchable short-circuit wind ing arranged so as to be displaceable by a displacement device over a wide range adjacent to the permanent magnets of the rotors. Magnetic field sensors disposed between the permanent magnets in each ring detect the polarity of adjacent permanent magnets in the other ring, and the short-circuit winding is closed or opened as a function of the sensor signals. In this way, the direction of rotation of the output shaft can be changed and the rotational speed and the output torque of the output shaft can be varied according to the position of the short-circuit winding with respect to the permanent magnets of the motor rotor and the generator rotor.


The internal order in the amorphous state of poly(ethylene terephthalate) (PET), prepared either by rapid cooling from the melt or by thermal annealing of melt pressed films above T g , has been studied using the microhardness technique. The hardness increase contribution due to physical aging, as well as the influence of the cooling rate on the hardness values of the glassy samples are independently discussed. The rate of creep under the indenter (creep constant) for these materials has been also investigated. It is found that the largest value for the creep constant corresponds to the highest cooling rate of the rapidly quenched samples (7500C/s), and to the starting melt pressed films. In addition, results reveal that the samples, showing the lowest degree of chain ordering, contain the lowest density of "embryonic" or "ordered" nanoregions; the latter controlling the viscoelastic behavior, as well as the induction time for cold crystallization. The isothermal crystallization of amorphous samples with different degree of internal order, studied by calorimetry, and the hardness increase occurring during the induction period prior to crystallization, are also comparatively discussed.


In the nineties a resurgence of historical biography has appeared on the Spanish modern historiography. This article explains this fact using a description of the sociocultural context and a survey of the biographical researchs materialized in doctoral thesis and several publications.


Refactoring means to rewrite pieces of code aiming to improve it internally but keeping the expected software behavior. In this paper we present the refactoring of an Internet of Things middleware based on Software-Defined Network. In a previous work we proposed a middleware to address issues we found in healthcare devices used to monitor patients with chronic illnesses in their homes. Software-Defined Network allowed the redesign of the middleware architecture to improve things management, its interconnection with services, and the deployment process of new monitoring scenarios. Refactoring process also extended the middleware to support multiple services in a single home network sharing the same network infrastructure. This work details an OpenFlow controller and an application developed to achieve our goals; we also present sample scenarios where our approach can be applied showing different services delivered in the same home network environment, and using data from all connected devices to build a digital representation of the physical realm.


The high heat load at the surfaces of the first x‐ray optical elements at the APS requires special measures to be taken to more completely utilize the beam. A conceptually new design for such an element, proposed, realized, and tested by M. Hart and conveniently called ''matchbox,'' is to be implemented at the IMCA‐CAT BM beamline as the first monochromator crystal. The requirements of the IMCA‐CAT companies for the BM beamline dictate that an optimization of the design is made for a given x‐ray energy range E=13 keV ±1 keV. A modification of the original design to improve the vacuum compatibility of the device was made in collaboration with M. Hart. A FEA optimization of the geometry is made using the ALGOR and ABAQUS programs. Determination of the resulting slopes and the useful crystal surface after the best compensation of the thermal distortions are also made. The surface profile obtained by the FEA study was used to perform a ray‐tracing analysis of the IMCA‐CAT BM beamline. The results of the ray‐tracing study will be presented.


Sr/86Sr data are presented for shallow-water carbonates plus vein and vesicle carbonate precipitated in basalt from Holes 871C, 872B, 877A, 878A, and 879A drilled during Leg 144 into Limalok, Lo-En, Wodejebato, MIT, and Tayuko-Daisan guyots, respectively. These data range from 0.70721 to 0.70862 (shallow-water carbonates) and from 0.70361 to 0.70767 (vein and vesicle carbonates) and compare with the range from 0.70720 to 0.70917 for Cretaceous to modern seawater. Notwithstanding the limits of strontium isotope stratigraphy as applied to Cretaceous and Paleocene sequences, these data may support the scenario of a "greenhouse" Cretaceous/Paleocene world in which (1) ocean saturation with respect to CaCO3 was low; (2) atolls drowned as they approached the equator on the northward-moving Pacific Plate; (3) carbonate platforms were permeable to significant seawater circulation and chemical exchange, in some cases until long after guyot formation; and (4) circulation was driven by a geothermal gradient from underlying volcanic pedestals that, in some cases, experienced seawater-basalt interaction on a magni- tude hitherto unreported from non-ocean ridge sites.


This study investigates the influence of native Malaysian academic staffs' characteristics on the research performance of University of Malaya (UM). The research performance is assessed by bibliometrics indicator, namely the number of publications, which is collected from Google Scholar. The academic staffs' characteristics in this study comprise of gender, ethnicity, academic position and academic age. The results show that the percentage of publications by male academic staffs are significantly more than that of by female academic staffs. Moreover, academic staffs who pose higher academic position or have longer years since awarded PhD are more likely to have higher number of publications. Ethnicity has also a significant influence on the research performance. Cross-tabulations and correspondence analysis are used to determine the mentioned objectives.


Bayor (Wien. Klin. Woch., 1926. No. 12) received very good results from the treatment of obesity with novazurol, administered intraglutaneously in an amount of 1-2 cubic meters. sant. every 6 days.


The aim of this study is to apply secondary education sports lessons with the blended teaching method. The quantitative research method was used in the study. The research was conducted in the fall semester of 2021–2022. 280 volunteer secondary school students continuing their education in Kazakhstan participated in the research. In the research, sports education was given to secondary school students with a 4-week blended education. In the research, the 'Sports and Blended Education' measurement tool developed by the researchers and compiled by experts in the field was used. The measurement tool was delivered to secondary school students via the online method and collected. The analysis of the data was made by using the SPSS programme, frequency analysis, t-test and the results were added to the research in the presence of tables. According to the results obtained from the research, it was concluded that there is a significant difference between the pre-test and post-test of the secondary school students and the blended education levels in sports lessons are high.

Keywords: Blended Education, Secondary Education, Distance Education, Education in Sports


The author looks at an organization's most valuable resource, its people, and the approaches that can be used to maximize their performance. The topics trace a path through business psychology from recruitment, selection and psychometrics to team-building and individual development.


Distal radius fractures in young adults are associated with high-energy trauma and in elderly people with low-energy falls. One of the distal radius fractures is the Barton Fracture (BF), a radiocarpal fracture-luxation whose production mechanism usually varies, the most common being a fall on an extended and pronated wrist. We present a 27-year-old male patient with distal radius epiphysis injury with radiocarpal dislocation following blunt trauma. Timely osteosynthesis with variable angle volar plate favored the restoration of distal radiocarpal and radioulnar biomechanics.


In this study, the importance of Three Pieces for Clarinet Solo by Igor Fyodorovich Stravinsky who was one of the important composers of contemporary period music was mentioned; the effects of, especially, the changes in the number of measures, breath marks, grace notes, nuance and accent articulations on performance were analyzed. In the light of this information it is aimed to create a source for clarinet performers. Three Pieces for Clarinet Solo composed by Stravinsky in twentieth century has an important place in terms of the transferring of musical characteristics of the time. The work consists of three pieces. The first two pieces were composed for A clarinet which is among the soprano group of clarinet family, the last piece was composed for B flat clarinet as a member of the same group. The composer employed chalumeau register, which has the most vibrant tone color of clarinet, in the first piece of the work and he used all registers of clarinet in the second and third pieces of the work. The first piece of the work is as tranquil as possible and it is a piece which is quite easy to be played with piano nuance until the last two measures. The second and the third pieces vary from pianissimo nuance to fortissimo nuance and necessitate professional performance in terms of finger techniques, metronome speed and the performance of nuance. In this study, first, composer identity of Igor Stravinsky and then the contribution of Three Pieces for Clarinet Solo in the repertoire of clarinet were discussed. Second, technical and musical difficulties in this work were analyzed and suggestions were presented to eliminate the difficulties for performance practice. In accordance with the obtained data, it is thought that this study is going to present a new perspective in the performance of the work for today's clarinet performers. Key Words: Stravinsky, Twentieth century, Clarinet, Three Pieces for Clarinet Solo, Nuance


A formula due to Gerjuoy [J. Math. Phys. 16, 761 (1975)] is derived in a straightforward way by use of second order perturbation theory.


In order to better meet the needs of brick mechanized packaging,design full-automatic brick packaging line intermittent separate mechanism,cam with partial gear combined with exercise, can be a smooth and efficient completion of the process of lift brick. According to the actual functio -nal requirements,calculate the size of the main components.Agencies coordinated through comput-ational analysis, operation with a fixed motivity driven, by changing the number of teeth of the partial gear to meet the separation requirements of the different thickness brick.By the dynamics simulation of the mechanism,to determine whether the mechanism meets the design requirements.


This thesis investigates the ionic transport properties of single, conical nanopores in polymers, as well as their applicability as single-molecule sensors. The pores were produced by selective etching of the damaged zones of energetic heavy ions (track-etching technique). More basic investigations of the shape of track-etched pores (by small-angle X-ray scattering, electron microscopy and conductometry) are also included, revealing smaller pore sizes on top of a membrane than inside the pore. Conical track-etched nanopores are cation selective and show asymmetric I-V characteristics, depending on pH value and concentration of the electrolyte. These properties result from their negative surface charges created during the etching process, which lead to an intrinsic asymmetric electric potential long the pore axis. Experiments show a maximum for the rectification at about 0.1 M KCl, in accordance with theoretical calculations. The selectivity of the pores depends on the direction of an applied concentration gradient, being higher for the lower concentration facing the small opening of the pore, again in agreement with calculations. The pores transport properties are strongly influenced by small concentrations of divalent cations. Conical polyimide pores have been found suitable to detect single DNA molecules passing through them via changes in the ionic current.


An account is given of some photographic observations made on long a.c. arcs at currents of 4600 to 6500 A. lasting for 0.56 to 1.12 sec. The arcs were photographed with a "still" camera and also with cine cameras running at 20 and at 1000 pictures per sec. The development of the arc is described and it is shown that the intensely luminous cloud of vapour produced by the arc commonly persists for 0.1 to 0.2 sec. and in one instance was still visible 0.5 sec. after the current had been interrupted.


Conventional color imaging has three channels—R, G, and B. In multispectral imaging within the visible spectrum, the number of channels increases in order to improve color accuracy and estimate spectral reflectance factor. Image quality criteria important in multispectral imaging
 include colorimetric accuracy, sharpness, registration, and low noise. The color transformation matrix, connecting camera signals with CIE tristimulus values, affects color accuracy and the visibility of image noise and misregistration when the multiple channels are combined to a colormanaged
 image. When the final goal is a color-accurate image for one set of illuminating and viewing conditions, the color transformation is often derived directly using nonlinear optimization minimizing the average color difference between spectrophotometer- and camera-based colorimetric coordinates.
 Optimization requires starting values and least squares minimizing spectral or tristimulus RMS error is typically used. Although it is effective for achieving convergence, the optimized matrix can result in a large reduction in image quality caused by noise propagation via the color transformation
 matrix. These concepts are reviewed.


Describes the development of components and subsystems for dispersion managed soliton transmission of optical time division multiplexed data at rates up to 100 Gb/s.