"Culture, Nation, and the New Scottish Parliament" asserts that while Scotland's new Parliament (1999) is a creation of laws, politics, and economics, some of the forces underpinning it are cultural, therefore constantly alive and insistently creative. Scotland may not be confined by, but has always lived within and moved forward and outward, through its signs and stories. In the moment of the new Parliament, it is time to cast up Scotland's accounts of past and present, and to review the nation's futures. Readers will find the usual signs of Scotland foregrounded, questioned, and re-energized as contributors trace the dynamic toward a Scottish Parliament. And they will find new signs, whether sounds, sights, or souvenirs come into play, revealing today's performance of a dynamic Scotland. Caroline McCracken-Flesher teaches the novel, the British eighteenth and nineteenth centuries, Scottish literature, and literary theory at the University of Wyoming.


The total flavonoid content (TFC), total polyphenols content (TPC), and in vitro antioxidant activity (AA) of six Bidens pilosa L., Asteraceae, populations harvested from different localities were evaluated in this work. The plants were separated in roots, stems, and leaves/flowers, and the influence of extraction methods was investigated.Areversed-phase high-performance liquid chromatography method (HPLC) was developed and employed to obtain characteristic HPLC fingerprints of the bioactive compounds present in the extractive solutions, which were correlated with the TFC, TPC, and AA. Extractive solutions of leaves/flowers presented a higher AA when compared with those obtained from other parts of the plant (IC50 of 35.35±0.10 µg/mL). The stem extracts presented the lowest AA (IC50 117.2±1.96 µg/mL). A direct correlation of AA with TFC and TPC was evidenced. The highest AA was obtained by dynamic maceration and was statistically different from the AA presented by the extractive solutions obtained by other extraction methods. The results of this work evidenced differences that can be found at different stages of development of phytopharmaceutical preparations from B. pilosa and highlighted the importance of using the concentration of marker compounds as well as HPLC fingerprints as quality control parameters.


This study aimed to determine and describe the management of village funds, especially the management of clean water funds in Naiola Village, South Bikomi District, North Timor Tengah Regency, through planning, organizing, implementing and monitoring for the welfare of the community. Planning for clean water fund management was carried out by involving the community to contribute ideas to fund the construction of clean water tanks and the construction of a pipeline network, through the Village Deliberation (MUSDus), Village Deliberations (MUSDes) and Planning Deliberations for Village Development (MUSREMBANGDes). The organization and management of clean water funds was carried out by forming an Activity Implementation Team (TKP). This research used descriptive research method with qualitative analysis. The results showed that the implementation of clean water fund management was not going as well as whatever was planned together at the time of in MUSDus, MUSdes, and MUSREMBANGDes. This is evidenced by the existence of making water storage tanks without the manufacture of pipeline.


Rodentmodelsshowdecreasedneuronalresponsestoestradiol(E2)duringaging(E2-desensitization) in association with reduced neuronal estrogen receptor (ER)- (cid:1) , but little is known about age changes ofE2-dependentastrocyticneurotrophicsupport.Becauseelevatedexpressionofastrocyteglialfibril-lary acidic protein (GFAP) is associated with impaired neurotrophic activity and because the GFAP promoter responds to ER (cid:1) , we investigated the role of astrocytic ER (cid:1) and ER (cid:2) in impaired astrocyte neurotrophic activity during aging. In vivo and in vitro, ER (cid:1) was increased greater than 50% with age in astrocytes from the cerebral cortex of male rats (24 vs 3 months), whereas ER (cid:2) did not change. In astrocytes from 3-month-old males, experimentally increasing the ER (cid:1) to ER (cid:2) ratio induced the aging phenotype of elevated GFAP and impaired E2-dependent neurite outgrowth. In 24-month-old male astrocytes, lowering ER (cid:1) reversed the age elevation of GFAP and partially restored E2-dependent neurite outgrowth. Mixed glia (astrocytes to microglia, 3:1) of both sexes also showed these age changes.Inamodelofperimenopause,mixedgliafrom9-to15-monthratsshowedE2desensitization: 9-month regular cyclers retained young-like ER (cid:1) to ER (cid:2) ratios and neurotrophic activity, whereas 9-month noncyclers had elevated ER (cid:1) and GFAP but low E2-dependent neurotrophic activity. In vivo, ER (cid:1) levels in cortical astrocytes were also elevated. The persisting effects of ovarian acyclicity in vitro are hypothesized to arise from steroidal perturbations during ovarian senescence. These findings suggest that increased astrocyte ER (cid:1) expression during aging contributes to the E2 desensitization of the neuronal responses in both sexes. ( Endocrinology 154: 2101–2113, 2013)


Attending to Richard Rorty and Stanley Fish on Roberto Unger and Jiirgen Habermas provides a basis for differentiating central tendencies in progressive social philosophy and legal analysis. In Contingency, Irony and Solidarity, Rorty posits Habermas as the leading nonironic defender of contemporary liberalism. Fish, an equal opportunity debunker, brings his tools in passing to Habermas and devotes an essay to Unger in his recent book, Doing What Comes Naturally. Each expresses a postmodern, antimetaphysical sensitivity without the continental heaviness represented in the work of either Habermas or


The present invention is the location of the server and the wireless network network using the stored in the terminal by changing the settings of the user interface device a user to easily be thereby generating a ring tone or beep to the terminal when the user to find a silent or vibration of the terminal to determine the location of the device relates to a method and system notifications. The invention transfer message for transmitting the message when the user authentication is completed in the user authentication step, and a user authentication step of verifying the user authentication to access the Internet server, including a preset instruction for changing settings of the terminal interface in a user terminal step and, when the instructions contained in the message sent from the message transmitting step recognized by the user terminal, is changed at the interface to change the user interface settings stored in the database setting change step and a changing step the interface configuration of the user terminal in response to the command depending on the settings of the user interface, including the notification step notifying the position of the terminal is characterized in that formed. Text messages, and user authentication interface, notification, alarm, ringtones


The sound quality (SQ) and sound perception assessments of electric vehicles (EVs) clearly differ from those of conventional internal combustion engine vehicles (ICEVs). Therefore, it is essential to describe and evaluate the SQ of EVs. To evaluate the SQ in EVs, it is necessary to organize evaluators for conducting subjective jury tests, which are time-consuming and labor-intensive. In addition, the evaluation results are subject to the evaluators themselves and other external interferences. With the advancement of machine learning and artificial neural networks (ANNs), this problem can be well solved. This paper outlines a model for SQ estimation in EVs based on a genetic algorithm-optimized back propagation artificial neural network (GA-BP ANN). Moreover, the correlation between the physical-psychoacoustical parameters and the subjective SQ estimations obtained from the jury tests was investigated in this study. It was found that the GA-BP ANN SQ model has many advantages in comparison with the multiple linear regression (MLR) model in terms of precision and generalization. In addition, this method is ready to be applied for rapidly evaluating the SQ in EVs without jury tests, and it can also be of high significance in dealing with the acoustical designs and improvements of EVs in the future.


We present an efficient method for the computation of homogenized coefficients of divergence-form operators with random coefficients. The approach is based on a multiscale representation of the homogenized coefficients. We then implement the method numerically using a finite-element method with hierarchical hybrid grids, which is a semi-implicit method allowing for significant gains in memory usage and execution time. Finally, we demonstrate the efficiency of our approach on two- and three-dimensional examples, for piecewise-constant coefficients with corner discontinuities. For moderate ellipticity contrast and for a precision of a few percentage points, our method allows to compute the homogenized coefficients on a laptop computer in a few seconds, in two dimensions, or in a few minutes, in three dimensions.


Objective: To assess the use of lactate as a marker of tissue hypoperfusion and as a prognostic index in critically ill patients. Methods: Prospective, longitudinal, observational study of 75 patients admitted to the pediatric ICU of Hospital de Clinicas of Universidade Federal do Parana, between November 1998 and May 1999. According to the lactate level on admission, patients were divided into group A (lactate > 18 mg/dl) and group B (lactate 18 mg/dl showed clinical signs of hypoperfusion on admission. The normalization or reduction of lactate levels at and after 24 hours of admission was significantly related with higher chances of survival


Abstract. Experience sampling often makes use of items that are similar to personality questionnaire items. Arguably, this opens up for item-popularity effects, where some respondents react to the ...


Summary In completely hypophysectomized male mice, treated with female hormone, the mammary gland rudiments do not respond. The gonads, accessories and adrenal cortex undergo regression regardless of the female hormone, present. The resorption of the pubic symphysis does not depend on the presence of anterior lobe material. A small fragment of prehypophysis enables the administered female hormone to induce growth of the mammary gland. Such a small pituitary fragment permits regression of the gonads, accessories and adrenal cortex. Caution must be urged in use of the term "physiologically hypophysectomized" anima1s.†


ence that would support the growth and development of a thinking ego. As Steiner saw it, it was the analyst's use of maternal reverie that enabled the inaccessible, radically unconscious feelings of pain and pleasure stored in the patient's "paleo or proto memory" to gradually surface towards consciousness and bring into being Ana's thinking, feeling mind. Steiner also raised a number of doubts regarding Pistiner's conceptualization, again via Rosenfeld, who implicitly counters the notion that a "detained" or "anti-communicative" projective identification could exist in pure isolation. "After all," Steiner argued, "even the most negative projective identification is a sort of communication". The broader point here, developed through the rest of his presentation, is that primitive modes of communication always operate in some kind of admixture with more organized modes. Steiner noted that colleagues in other theoretical traditions, such as Andr e Green, Thomas Ogden, Giuseppe Civitarese and the Botellas, had forged different vocabularies for describing "disappeared" states of mind such as Ana's. This theme of translation across different traditions was strongly developed by the second respondent to the paper, John Muller (Austen Riggs Center, Massachusetts). Muller recoded the key symbolic elements in this clinical material through a semiotic framework derived from the great American pioneer of this modern sub-discipline, C. S. Pierce. Bion's alpha function, he suggests, can be construed semiotically as "the capacity to take things as signs", which provides "the basis of all thinking, conscious as well as unconscious". Semiotics, Muller argued, offers a precise vocabulary for distinguishing different levels of symbolization, from the "iconic" showing of psychic deadness registered in the analyst's internal response, to the 'indexical' representation of loss by means of "contiguity and separation" (the patient's wearing of the dead brother's jacket as signifier at once of his absence from and his presence to her), and finally to what Pierce terms the "interpretant" component of the sign, its transformation by its receiver into "a new sign". In a helpfully compressed illustration of his framework, Muller showed how the transformations of Ana's somatic symptom could be understood in terms of semiotic development. The symptom, he suggested, "joins in the conversation through a progression from the hand as icon, showing inflammation and painful swollen arousal, to the hand as index contiguously marking the site of masturbation, to the need for a curtain as a symbol to establish a boundary and contain painful arousal." Implicit in Muller's presentation, then, was a conception of different theoretical frameworks as 'transformations' of one another. Bion's theory of psychic function is both supported and remade in the Lacanian account of absence as an effect of language – the word, for Lacan, being 'a presence made of absence'. The remaining time was taken up by Pistiner's responses to the two discussants, which focused especially on Steiner's discussion of projective identification. She expressed sympathy with the aim, advanced by Bion and Rosenfeld, of enlarging the concept of projective identification. She raised some points of disagreement with Steiner, first of all on the question of "detained" projective identification, which she saw not as a problem of non-communication but, more fundamentally, of non-existence. She also disagreed with Steiner's emphasis on the place of reason in the analyst's function, suggesting that when working with very primitive forms of projective identification, the analyst must draw on elements of psychic life that preceded reason and language. Pistiner closed her response, and the session, by speculating on possible points of contact between Bion's grid and Pierce's semiotics – might the movement from E to C on the grid correspond to the movement out of iconic representation? And might iconic representation itself be understood as a version of transitional space?


&NA; ▪ The Dutch MIRROR study has found that micrometastases detected on sentinel lymphnode biopsy should not be ignored, reported researchers. Nodal metastases of 0.2 to 2.00 mm could put women with breast cancer at significantly higher five‐year risk of axillary recurrence.


According to recent experiments into stem and tumor cells, the asymmetry of time could be an important factor in the cellular world. In this paper an alternative idea is proposed to explain some mechanisms that are not well understood today.


Currently, IoT systems display a poor level of security, as 50% of IoT devices are vulnerable to severe attacks, according to research. In an attempt to ameliorate the situation, we propose STRIPED, a threat analysis technique that focuses particularly on threat scenarios involving IoT devices that can be physically accessed by attackers. We evaluate STRIPED in a two-pronged way. First, we assess its performance compared to STRIDE (from which STRIPED is derived) in the context of a case study from the manufacturing industry. Second, we gather the feedback of 8 security experts working in a large, multinational company that specializes in secure IoT products for the domains of automotive, industrial, mobile and smart-home applications. These initial evaluation attempts provide encouraging evidence and suggest our method is a step in the right direction of facilitating security-by-design in IoT systems, especially industrial ones.


The model of (reactive) probabilistic automata was introduced by Rabin in 1963 [10], generalising non-deterministic automata by assigning probabilities to transitions. Such an automaton associates with a word a value between 0 and 1, which is the probability that the run is accepted. This extended abstract presents recent progress on the value 1 problem for probabilistic automata, which asks whether given a probabilistic automaton, there exist words accepted with arbitrarily high probability. Since its introduction by Gimbert and Oualhadj in 2010 [8], the value 1 problem has been studied at great depth, leading to the development of new tools of algorithmic, algebraic, and topological nature. We report on a recent paper which introduces a topological approach called the prostochastic theory for understanding the value 1 problem [6, 7].


Though I was asked for this contribution because I am a 'state' or 'public' archaeologist, I have no mandate to speak for any other such archaeologists in Australia, nor do I intend to discuss the interpretation or administration of the various acts which throughout most of Australia limit and control the activities of professional archaeologists. I suspect that it is not the actual details of legislation, but the principles of its interpretation which is of most interest and relevance to the first symposium of the AAA,


Hb Redondo [β92(F8) His→Asn] illustrates how post‐translational structural modifications may modify the phenotypic expression of an unstable hemoglobin. This variant was found in a Portuguese patient suffering from a chronic hemolytic anemia. The electrophoretic pattern demonstrated that it occurred in two forms, both being semi‐hemoglobins: the fastest one migrating like HbS and the other like HbA2; after a few days of storage at 4°C the intensity of the slowest Hb fraction decreased while that of the other increased proportionally. In both cases, the RP‐HPLC analysis of the tryptic digest of the aminoethylated β chains demonstrated the presence of an abnormal βT10 peptide carrying a His→Asx substitution. Microsequence study of these two peptides demonstrated that the slowest abnormal Hb fraction had a β92 His → Asn substitution and the fastest a His → Asp at the same site.


An investigation of the two-point autocorrelation function of cD clusters is presented. As the identification of cD galaxies is not likely to be affected by possible projection contamination that may exist in cluster catalogs, their clustering properties can provide an important, independent check of the influence of systematic errors in the cluster identification process on determinations of the cluster-cluster function. The clustering of cD clusters described by the spatial and angular two-point autocorrelation functions is found to be quite similar to that of Abell clusters in general. 65 refs.


In this paper first we discuss about statistical manifolds and immersed hyper surfaces in R. We show that every centro-affine hyper surface is a statistical manifold realized in R. Then proved that dualy flat statistical manifold can be immersed as a centroaffine hyper surface. Also observed that a Blaschke immersed manifold is a statistical manifold. Then in the case of the dualy flat statistical manifold (S,∇e,∇m) we show that if all ∇eautoparallel submanifolds are exponential then S is an exponential family. Also prove that submanifold of a statistical manifold with ∇e connection is ∇eautoparallel if it is exponential family.


In this paper, we present the design of a focusing dielectric lens, which is based on the concept of a Fresnel step lens. The concept and design of the lens is introduced. Different lenses are surveyed and compared using simulations and measurements with a frequency-modulated continuous-wave (FMCW) radar. The new design shows a smaller focus than the reference focus lens antenna while reducing the size by up to 53 % and the weight of the lens by nearly 48 %. In addition, the Fresnel-based lenses show a frequency dependency, which can be utilized to adjust the focal length.


On network-based computing systems, multi-instalment scheduling (MIS) has been shown to be an efficient method for reducing the time needed for processing large-scale divisible loads. Because the size of the output compared to the size of the input was considered to be minimal, the result backpropagation was not considered by traditional MIS techniques. Although the MIS-RR strategy incorporated the result retrieval phase along with a periodic MIS strategy, the energy effects of the strategy are yet to be studied. In this paper, we develop a comprehensive simulation framework using SimPy and use it to study the real-world time and energy effects of the MIS-RR strategy. We demonstrate the time and energy trade-offs that are required for an effective schedule. We analyse the strategy based on a variety of influencing factors such as network scalability, number of instalments, and overheads, and then try to determine the maximum number of processors to employ for a given load size and a given energy budget. This latter finding is crucial for system administrators when determining the number of resources to be deployed for a given load size and a power budget.


While a number of studies have investigated adsorption and microbial immobilization as sulfate (SO42−) retention mechanisms, few have investigated these processes under field-like conditions on a r...


Objectives: To generalize the conventional delta–wye and wye–delta conversions. Methods/Statistical Analysis: The delta–wye and wye–delta conversions have been used to simplify complex electric circuits (networks) consisting of resistors. Three terminal networks consisting of resistors and voltage sources in a wye configuration and in a delta configuration are compared. Findings: In this paper we obtained the conversion relations for emfs from the delta configuation to the wye configuration and vice versa. As an example of the generalization, the conversions are applied to a Wheatstone-bridge type circuit of five batteries and five resistors to obtain its Thevenin's equivalent. The conversions are applicable to ac as well as dc circuits. As an example of ac circuits the currents through unbalanced loads in a wye configuration connected to a three-phase generator in a delta configuration are calculated. Application/Improvements: The generalized conversions allow to simplify dc and ac circuits.


In recent decades, the influence of parenting styles and practices on children's emotional and mental health has been recognised (Gardner & Shaw, 2009). This edition's research digest is divided into two thematically-linked parts. The first comprises studies which focus on the links between parental factors and behaviours and various aspects of child social, emotional and cognitive development. We have included studies which investigate, for example, factors which mitigate the risks post to children exposed to prenatal maternal psychological distress or childhood abuse (Schechter et al., 2017; Tracey, Salo & Appleton, 2018), the role of cultural norms and variations in determining the impact of parenting styles (Lansford et al., 2018) and the links between parental and childhood depression (Lewis et al., 2018; Eckshtain et al., 2018). These studies demonstrate both the intergenerational transmission of emotional distress and maladaptive behaviours, and the growing understanding of factors which could be co-opted in the service of interrupting these damaging cycles. The importance of supporting parents with the challenges of child-rearing, particularly those parents who may be put 'at-risk' by experiences of poverty, trauma, abuse or mental health difficulties, has been incorporated into multiple government policy documents (e.g., England NHS, 2016). As such, the second part of this digest focuses on recently published research into interventions with parents aimed at supporting child mental health. Ryan, O'Farrelly & Ramchandani's (2017) review of the effectiveness of six parenting programmes, two of which are recommended by NICE, and all of which are widely available in the UK, is a helpful overview of the benefits and limitations of these largely behavioural and educational programmes. Several recent research studies attempt to evaluate interventions aiming to address some of the limitations of parent training programmes, for example a parenting group adapted for parents of migrant and displaced children (Annan etal., 2017), an intervention focussing on facilitating parental mindfulness (Bögels et al., 2014), and a model which privileges the establishment of parental engagement in addition to the traditional focus on parenting skills and strategy implementation (Piotrowska et al., 2017). Although the crucial importance of concurrent parent work to the effectiveness of child psychotherapy has been recognised (Trowell et al., 2007), there is a dearth of empirical research into this area. We have included Whitefield and Midgley's (2015) qualitative examination of therapists' experiences of working with parents' own childhood experiences in concurrent parent work, as well as a systematic review of parental involvement in adolescent depression interventions (Dardas, van de Water & Simmons, 2018). Both these studies highlight the importance of the parental context when working therapeutically with children, and call for further research into how and when work with parents can be most helpfully offered. JOURNAL OF CHILD PSYCHOTHERAPY 2018, VOL. 44, NO. 2, 275–283 https://doi.org/10.1080/0075417X.2018.1501719


1,1′-Bis(o-carborane),a three-dimensional analogue of biphenyl,is formally formed by two o-carborane clusters with a direct linkage of a carbon-carbon single bond which is formed with one skeletal carbon atom from each subcluster.In this paper the syntheses,structure and properties of 1,1′-bis(o-carborane) are overviewed,with an emphasis on its reactivity.Where appropriate,a comparision is made with that of o-carborane.Research has shown that,similar to its "monomer" o-carborane,1,1′-bis(o-carborane) can undergo various reactions such as substitution at carbon,substitution at boron,partial degradation or deboronation,reduction(cage opening),and thermal rearrangement,while some reactions such as the reduction show different pattern.The potential applications of the biscarborane derivatives have also been briefly discussed.


Introduction: Re-Thinking Innovation - Joseph Wong (University of Toronto, Munk School of Global Affairs, Innovation) and Dilip Soman (University of Toronto, Rotman School of Management, Marketing) Chapter 1: Poverty Invisibility and Innovation - Joseph Wong Chapter 2: Behaviourally Informed Innovation - Dilip Soman Chapter 3: Appropriate Technologies for the Global South - Yu-Ling Cheng (University of Toronto, Chemical Engineering and Applied Chemistry) and Beverly Bradley (University of Toronto, Centre for Global Engineering) Chapter 4: Globalization of Biopharmaceutical Innovation: Implications for Poor Market Diseases - Rahim Rezaie (University of Toronto, Munk School of Global Affairs, Research Fellow) Chapter 5: Embedded Innovation in Health - Anita M. McGahan (University of Toronto, Rotman School of Management, Associate Dean of Research), Rahim Rezaie and Donald C. Cole (University of Toronto, Associate Professor) Chapter 6: Scaling Up: The Case of Nutritional Interventions in the Global South - Ashley Aimone Phillips (Registered Dietitian), Nandita Perumal, Carmen Ho (University of Toronto, Doctoral Fellow, Political Science), and Stanley Zlotkin (University of Toronto, Hospital for Sick Children, Paediatrics, Public Health Sciences and Nutritional Sciences) Chapter 7: New Models for Financing Innovative Technologies and Entrepreneurial Organizations in the Global South - Murray R. Metcalfe (University of Toronto, Centre for Global Engineering, Globalization) Chapter 8: Innovation and Foreign Policy - Janice Gross Stein (University of Toronto, Political Science) Conclusion: Inclusive Innovation - Will Mitchell (University of Toronto, Rotman School of Management, Strategic Management), Anita M. McGahan Glossary About the Contributor


Two studies examined the construct validity of emergent readers' motivation measures. Both studies directly assessed reading skills. Motivation was measured via self-report inventories, including existing and new items derived from the Preschool Reading Attitudes Survey (PRAS), the Motivated Reading Questionnaire (MRQ), and the Motivated Reading Profile (MRP). Parent and teacher measures of emergent readers' motivation were also administered. Study 1 findings indicated significant correlations within readers' self ratings and between teachers' and parents' ratings of children's motivation, but little consistency between these ratings and children's self-ratings. Study 2 replicated many Study 1 findings and indicated stability in children's motivation measures.


Main purpose of this research is to study the strategy of building up the management system and evaluate the strategy of management in Private Education Institution of Early Childhood Education. This qualitative research was support by open-end question questionnaire. There is the implement of rules checking by the 3 experts including Board of Institution, Lecturer and Bangkok Metropolitan Basic Education Commission. The research is specifically focusing on 19 private schools and using 50 people to analyze and descript. The result of this research shows that The Management of Proactive learning for developing quality of Early Childhood Education of 21st century must implement the vision, short term target, long term target and must create the strategy of Education Management in order to consistent with target of Education in 21st century. Everybody require to study from Early Education to Higher Education and to the rest of the life is 3r x 7c3r by using evaluation of internal and external quality from Office of the Higher Education Commission and aim to standard or expect quality that must affect to student by using Ordinary Flag.


Zinner syndrome is a rare congenital anomaly of the mesonephric duct, characterized by a triad of symptoms: seminal vesicle cysts, ipsilateral renal agenesis and ejaculatory duct obstruction. This leads to a severe complication — oligozoospermia/azospermia, which can subsequently cause infertility. The widespread use of medical imaging increases the probability of incidental detection. Namely, magnetic resonance imaging (MRI) is the imaging modality of choice for making a diagnosis.   Study purpose: to optimize patient routing in Zinner syndrome, as well as to minimize the risk of misdiagnosis or missed pathology, by providing strong and weak points for each modality.   Materials and methods: we present two clinical cases of Zinner syndrome.  The first one is a complicated course in a 25-year-old patient, and the second one is accidentally discovered in a 27-year-old patient. The patients underwent a comprehensive diagnostic panel, including: ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI). The results obtained were analyzed in the light of available literature data.   Results: in most cases, Zinner syndrome is an incidental finding during. The diagnosis based on these imaging methods and the correct patient routing allowed us to make a timely and correct diagnosis, followed by decisions on further treatment tactics.   Conclusion: Zinner syndrome is a rare disease and is often diagnosed based on imaging findings only. A radiologist and clinician need to know about the diagnostic criteria for this syndrome in order to successfully diagnose and determine the optimal treatment tactics.


America's churches have fallen on hard times. But this crisis, says Wuthnow, is more than economic; it is at bottom spiritual. He points to both the failure of the clergy to confront their financial problems head-on, and their neglect of the real spiritual needs of their predominantly middle-class congregations. He offers specific suggestions for more effective ministry.


Background The gold standard for diagnosis of neonatal jaundice is total serum bilirubin (TSB) measurement. This method, however, is invasive, painful, and costly in terms of workload, time, and money. Moreover, repeated blood sampling may lead to significant blood loss, which is of particular concern in preterm infants. To overcome these drawbacks, non-invasive methods of bilirubin measurement have been proposed. Transcutaneous bilirubinometry (TcB) determines the yellowness of the subcutaneous tissue of a newborn infant by measuring the difference between optical densities for light in the blue and green wavelength regions. Objective To evaluate the accuracy of transcutaneous bilirubinometry for estimating TSB levels in neonatal jaundice. Methods Subjects were infants aged 5 mg/dL were correlated to TSB > 5 mg/dL, with 100% sensitivity and 83.3% specificity. This cut-off point was obtained from a receiver-operator characteristic (ROC) curve with AUC 99.3% (95%CI 97.9 to 100%; P< 0.001).The correlation coefficients (r) for TSB and TcB measurements on the forehead were 0.897 (P<0.001). Conclusion Transcutaneous bilirubinometry can be used to accurately estimate TSB levels in neonatal jaundice, and may be useful in clinical practice as a non-invasive method to reduce blood sampling.


The stylistic method of revealing regularities, formed by the 19th century and dominating up until recently, proves to be ever less relevant to architectural and artistic processes of the Contemporary (Newest) times. To systemize the entire historical experience of architecture as a whole, more profound generalizations are required. An essential prerequisite for such generalizations appears to be the philosophical context of the paradigm shift: tradition — modernity — postmodernity. Without a clear understanding of all the differences between these paradigms, it is impossible to talk about the processes taking place in the architecture of the Contemporary times. The fundamental rejection of semantic binary oppositions (good/bad, beautiful/ugly, high/low, sacred/secular, etc.), typical for postmodernism, has entailed the issue of criteria for the value of art works, and consequently the criteria for art at large. The aim of this work is to demonstrate that the mimetic principle underlies the totality of the valuable qualities inherent in traditional architecture. And that, on the contrary, a gradual departure and subsequent factual rejection of this principle became one of the main reasons for both the emergence of the modern architecture phenomenon and its present crisis. The panoramic, holistic view of architectural development combined with the philosophical context of paradigmatic shift, allows not only to see the logic in the tortuous paths of the form making, but also gives the basis to build a system of universal criteria for architectural analysis.


tion, there are two other short contacts, namely N . . . O(1) (II0rI), 3.084 A and N . . . O(1), 2.752 A. The atom O(1) belongs to the same molecule while the atom O(1) (II0ia) lies approximately on the line C(2)-N. The arrangement of this latter type is very similar to that of carbonyl oxygen [O(1")] around the N H + group in valine hydrochloride (Parthasarathy, 1966) or in 7-glycine (Iitaka, 1961).


In this paper a design method for associative memories using discrete-time cellular neural networks (DTCNNs) is presented. The developed approach enables the number of cell interconnections to be reduced by exploiting the features of multilevel output functions and utilizing proper neighbourhoods which avoid line-crossings among interconnections in the designed networks. As a consequence, the suggested technique greatly simplifies the VLSI implementation of the proposed DTCNN architecture.


From Earthwise Jump to navigation Jump to search Gent, C M A, Stewart, M A, Evans, D J, Lamb, R, Alcalde, J , Heinemann, N and Akhurst, M C. 2015. A summary of the methodology for the seismic stratigraphic interpretation for the 'GlaciStore' bid to IODP. (Energy and Marine Geoscience Programme) British Geological Survey Internal Report, OR/15/072. 1 British Geological Survey 2 University of Manchester 3 University of Aberdeen 4 University of Edinburgh


A prescription is a legal document given to a pharmacist by a licensed physician to produce or administer pharmacological agents/medications to diagnose, cure, or treat an illness. A written prescription is the most common method of prescribing medications in the Philippines. The unreadability of a doctor's handwriting when prescribing medication leads to medication errors. Use of an incorrect dose of medication, or even death. As a result, doctors must rely on stenography or shorthand writing to quickly write vital information on prescriptions. The study aims to develop a device that helps pharmacists in performing jobs effectively and helps the pharmacy to translate the sloppily written prescriptions. In data gathering, the researchers visited two doctors to collect data in a handwritten prescription samples and two doctors wrote the names of five antibiotics on a piece of paper 200 times, producing 1000 handwritten prescription samples. This study conducted a data gathering process flow to come up with the final dataset with 11,000 iamges. The study showed also the training process of Custom SSD Mobilenet v2 Detector with the pre-process handwritten antibiotic names. The validation of the detection model are 92.4% accuracy and 57.4 milliseconds speed. The detection model was uploaded to the raspberry pi for the researchers to develop a device that can detect antibiotic names. The performance and functionality of the whole system were tested and evaluated. The system accurately detects the 39 antibiotic names out of 45 with an f-score of 87% accuracy. This shows and validates that the system is efficient and effective in detecting antibiotic's names.


The well known Poincare's Theorem state: The rotation number of an orientation preserving circle homeomorphism is rational if, only if, the homeomorphism has a periodic point of period equal to denominator of the rational. In this monograph we study results analogous, to the result above mentioned, for homeomorphisms of A = S1 × I homotophics to the identity. More precisely, we study the famous Poincare Birkhoff Theorem and some versions obtained by J. Franks [13]. This it will be done imposing some conditions in the rotation set, which is generalization of the rotation number for circle homeomorphisms.


The article investigates the ways to measure the communication links in political networks. The author considers the new technologies that analyze user data and build graphs with nodes. Much attention is paid to the development of Internet measurement in the field of political communications.


Phosphatidylinositol 3‐kinase (PI3K)/Akt‐mediated regulation of Raf/MEK/ERK activity has been identified in immune cells, the central nervous system, and skeletal muscle; however, an interaction has not been established in non‐small cell lung carcinoma (NCSLC).We examined Akt‐Raf cross‐talk in NSCLC by immunofluorescence (IF), co‐immunoprecipitation (co‐IP) and manipulation of target gene expression. While transiently expressed PI3K and Akt decreased MEK/ERK activity, functional‐deficient PI3K and Akt elevated MEK/ERK activity, suggesting that the PI3K/Akt pathway negatively regulates MEK/ERK activity in NSCLC. IF revealed Akt co‐localization with Raf but not Ras or ERK. Additionally, co‐IP confirmed an increased Akt‐Raf association and enriched cytoplasmic Raf following Akt activation. PI3K/Akt, but not MEK/ERK signaling, appears to be essential for maintaining malignant characteristics of NSCLC cells. Furthermore, both the promoter activity and protein levels of VEGF and MMP‐2 showed a PI3K/Akt‐, but not MEK/ERK‐dependent, pattern. Moreover, interference with PI3K/Akt function, but not that of MEK/ERK, decreased cell viability. These data reveal regulation of Raf/MEK/ERK by the PI3K/Akt pathway, a novel finding in NSCLC. This finding is highly relevant to understanding the pathogenesis and behavior of NSCLC and may be of value for future therapeutic directions.


An update to the MRC image-processing software package is described. It includes improvements to the Ximdisp display program for use on images of helical assemblies or tilt-pair single-particle cryoEM images.


In the second half of the 20th Century coastal dune grasslands in the Netherlands, belonging to the grey dunes, have suffered from severe
grass and shrub encroachment, mainly due to prolonged stabilisation, nitrogen deposition and rabbit decline. The loss of biodiversity is counteracted
by different nature conservation measures, such as cattle grazing, mowing, sod cutting and the restoration of blow outs. Besides, wild
fire might also be considered as an opportunity in order to restore grey dunes. In the Amsterdam Water supply Dunes in 2002 shallow sod cutting
was experimentally applied in degraded grey dunes. Research mainly focussed on the effects of sod cutting on soil parameters and vegetation
composition in plots before and after sod cutting, grass encroached control plots and well developed grey dune plots. Besides, some insect
groups such as butterflies and grasshoppers were investigated. In 2004 a wildfire destroyed a small thicket of Hippophae rhamnoides in an environment
of Taraxaco-Galietum veri grey dunes. Vegetation and soil parameters were studied in 2011. Small plots were situated in burnt scrub
and unaffected scrub (control), and were compared with adjacent grey dunes. In dune grasslands of the Taraxaco-Galietum veri shallow sod
cutting led to a successful recovery of the vegetation and come-back of rabbits and characteristic butterfly and grasshopper species within a
period of eight years. The degraded Phleo-Tortuletum ruraliformis grey dunes also show a recovery but they respond more slowly to sod cutting,
probably due to temporarily higher rabbit numbers and lower nutrient availability. The coverage of ruderal species significantly decreased on
both sites. In burnt scrub Hippophae rhamnoides did not return. The average number of grey dune species was significantly higher in comparison
with the unaffected scrub, but not as high as in the adjacent grey dune plots. The success parameters of the shallow sod cutting are a small
scale approach, the presence of well-developed relic populations of grey dune vegetation with the accompanying fauna species and the
return of an open, varied vegetation with bare sand. The development after wildfire illustrates that Hippophae scrub can be converted into
grey dune habitat by fire. Rabbits which are present in high numbers on all sites probably played a positive role in the recovery of grey dunes.


PROBLEM TO BE SOLVED: To provide an apparatus for gel electrophoresis capable of producing a gel which has a well capable of holding a sample volume that is at least double the well volume of the current methods and which does not decrease resolution of separated macromolecule bands.SOLUTION: An apparatus for gel electrophoresis comprises: a gel cassette; and a comb having at least one wedge-shaped tooth. This enables production of a gel of a particular thickness that maintains the same sample height above the gel as a standard well of particular width and thickness.


A novel agar-degrading marine bacterium, SH-1 strain, was isolated from seashore of Namhae at Gyeongnam province, Korea. The SH-1 strain exhibited 98% similarity with Alteromonas species based on 16S rDNA sequencing and named as Alteromonas sp. SH-1. Alteromonas sp. SH-1 showed agarase activity of 348.3 U/L (1.67 U/mg protein). The molecular masses of the enzymes were predicted as about 85 kDa and 110 kDa by SDS-PAGE and zymogram. The enzymatic activity was optimal at 30℃ and the relative agarase activity was decreased as temperature increase from 30℃ and thus about 90% and 70% activities were shown at 40oC and 50℃, respectively. The optimum pH was 6.0 for agarase activity in 20 mM Tris-HCl buffer and activities were less than 70% and 85% activity at pH 5.0 and pH 7.0, respectively, compared with that at pH 6. Agarase activity has remained over 90% at 20℃ after 1.5 hour exposure at this temperature. However, its activity was less than 60% at 30℃ after 0.5 h exposure at this temperature. The enzymes produced agarooligosaccharides such as agaropentaose and agarotriose from agarose, indicating that the agarases are α-agarases. Thus, Alteromonas sp. SH-1 and its agarases would be useful for the industrial production of agarooligosaccharides which are known as having anticancer and antioxidation activities.


This first book-length history of the AFT provides a comprehensive view of events which have shaped teacher activism and of issues which have defined the AFT s role in teacher unionism.From its turbulent beginnings in 1916 in Chicago, where the seeds of the movement took root, to the 1961 teacher strike in New York City, which proved the union s effectiveness, the American Federation of Teachers union has provided a simulacrum of industrial organizational patterns common to the labor movement in this country. Deriving its principal strength from such modes, the AFT was crisis oriented from the start, and is thus distinguished from its rival union the NEA, a more conservative, profession-oriented group.From original, unpublished sources, including the AFT s files, and from personal interviews, William E. Eaton has made an original, and significant, contribution to our understanding of current problems in education. As a new kind of revolution seems to be changing the fabric of our school system, this is an important book for our time."


Social justice is a principle that will be achieved through zoning policies to accelerate the participation of education. In practice, there is a relationship between education policy and social justice, the complexity of justice is following the individual who runs it, but the social justice principle policy for the community has not been realized. This research uses a qualitative method with a case study approach. The object of this research is Temanggung Regency. This research was conducted in September 2019 to January 2020. The results showed that the zoning policy gave rise to parental disappointments such as the occurrence of blank spot areas, restrictions on choosing schools, and national exam scores that were not used in-school registration. The factors underlying the injustice in the community are the unequal condition of facilities and infrastructure in each school and the distribution of schools in each region that is not the same.


Proximate composition and the contents of free sugars, minerals, fatty acids, amino acids and in vitro digestibility of mixed pollen load were analyzed. The protein in pollen load per 100g was 25.2g, lipid 5.4g, non-fibrous carbohydrate 50.0g and fiber 10.4. Free sugars in pollen load, as dry basis g per 100g, was fructose 26.6g, glucose 13.1g, sucrose 0.2g, maltose 1.3g, melezitose 0.02g and F/G ratio was 2.0. The content of mineral in pollen load was in the order K > P > Mg > Ca > Fe > Na > Mn > Zn > Cu. Unsaturated fatty acid of pollen load was about 69.1% and polyunsalturated fatty acid being about 50.3%. The ratios of SFA : MUFA : PUFA and PUFA : SFA were 0.61 : 0.37 : 1.00 and 1.63 respectively. The total amino acid contained in pollen load 22,337.5mg/100g and total essential amino acid was 39.2% of the total amino acid. proline was the most abundant amino acid (2,824.7 mg/100g),followed by Glu, Leu, Asp, Val, Phe, Ile, Ala and Thr. E/T ratio of protein in pollen load was 2.03 ; protein score, 65.2(Lys) : A/E ratio(egg), 61.7(Lys) : amino acid score, 51.7% after 1hr and on non-fibrous carbohydrate was 80.6%. But that of protein was 67.3% after 1hr, 75.5% after 2hr.


The present invention relates to novel 4-metylpyridopyrimidinonforbindelser of formula (1) and salts thereof, their synthesis and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Ka).


ABSTRACT Pulsed-field gel electrophoretic analysis of 2,144 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from patients in Spanish hospitals over a 7-year period revealed 17 predominant profiles. Typing showed the replacement of Iberian clone E1 (ST247-MRSA-I) by two prevalent clones, E7 and E8, that are closely related to each other and have the same genetic background as ST125-MRSA-IV.


[1] Dunning J, Prendergast B, Mackway-Jones K. Towards evidence-based medicine in cardiothoracic surgery: best BETS. Interact CardioVasc Thorac Surg 2003;2:405–409. [2] Wright G, Manser RL, Byrnes G, Hart D, Campbell DA. Surgery for nonsmall cell lung cancer: systematic review and meta-analysis of randomised controlled trials. Thorax 2006;61:597–603. [3] Manser R, Wright G, Hart D, Byrnes G, Campbell DA. Surgery for early stage non-small cell lung cancer. Cochrane Database Syst Rev 2005; 1:CD004699. [4] Lim E, Baldwin D, Beckles M, Duffy J, Entwisle J, Faivre-Finn C, Kerr K, Macfie A, Mc Guigan J, Padley S, Popat S, Screaton N, Snee M, Waller D, Warburton C, Win T. Guidelines on the radical management of patients with lung cancer. Thorax 2010;65(Suppl 3):iii1–iii27. [5] Darling GE, Allen MS, Decker PA, Ballman K, Malthaner RA, Inculet RI, Jones DR, Mc Kenna RJ, Landreneau RJ, Rusch VJ, Putnam JB Jr. Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than hilar) non-small cell carcinoma: results of the American College of Surgery Oncology Group Z0030 Trial. J Thorac Cardiovasc Surg 2011;141:662–668. [6] Wu Y, Huang ZF, Wang SY, Yang XN, Ou W. A randomized trial of systematic nodal dissection in resectable non-small cell lung cancer. Lung Cancer 2002;36:1–6. [7] Izbicki JR, Passlick B, Pantel K, Pichlmeier U, Hosch SB, Karg O, Thetter O. Effectiveness of radical systematic mediastinal lymphadenectomy in patients with resectable non-small cell lung cancer: results of a prospective randomized trial. Ann Surg 1998;227:138–144. [8] Passlick B, Kubuschock B, Sienel W, Thetter O, Pantel K, Izbicki JR. Mediastinal lymphadenectomy in non-small cell lung cancer: effectiveness in patients with or without nodal micrometastases – results of a preliminary study. Eur J Cardiothorac Surg 2002;21:520–526. [9] Sugi K, Nawata K, Fujita N, Ueda K, Tanaka T, Matsuoka T, Kaneda Y, Esato K. Systematic lymph node dissection for clinically diagnosed peripheral non-small cell lung cancer less than 2 cm in diameter. World J Surg 1998;22:290–295. [10] Doddali C, Aragon A, Barlesi F, Chetaille B, Robitail S. Does the extent of lymph node dissection influence outcome in patients with stage I non-small cell lung cancer. Eur J Cardiothorac Surg 2005;27:680–685. [11] Okada M, Sakamoto T, Yuki T, Mimura T, Miyoshi K, Tsubota N. Selective mediastinal lymphadenectomy for clinico-surgical stage I non-small cell lung cancer. Ann Thorac Surg 2006;81:1028–1032. [12] Gajra A, Newman N, Gamble GP, Kohman LJ, Graziano SL. Effect of number of lymph nodes sampled on outcome in patients with stage I non-small-cell lung cancer. J Clin Oncol 2003;21:1029–1034. [13] Zhang GQ, Han F, Gao SL, A DL, Pang ZL. Two patterns of mediastinal lymph node resection for non-small cell lung cancer of stage IIIA: survival analysis of 219 cases. Ai Zheng 2007;26:519–523. [14] Keller SM, Adak S, Wagner H, Johnson DH. Mediastinal lymph node dissection improves survival in patients with stages II and IIIa non-small cell lung cancer. Eastern Cooperative Oncology Group. Ann Thorac Surg 2000;70:358–365. [15] Izbicki JR, Passlick B, Karg O, Bloechle C, Pantel K, Knoefel WT, Thetter O. Impact of radical systematic mediastinal lymphadenectomy on tumor staging in lung cancer. Ann Thorac Surg 1995;59:209–214. [16] Barnard J, Dunning J, Musleh G, Odom N. Is there a role for the use of radical lymph node dissection in the surgical management of resectable non-small cell lung cancer. Interact CardioVasc Thorac Surg 2003;3: 294–299.


Due to their merits of high efficiency,high power density and high reliability,permanent magnet motors have gained great attention in "motion control" course in Jiangsu University.Differing from the existing ones,such as DC motor and induction motor,the experimental permanent magnet motor drive requires close loops of rotor position,rotor speed and current.This paper designs and implements a DSP-based permanent magnet motor drive for experimental teaching.Moreover,it gives experimental examples.The developed platform will be of benefit to the study of comprehensive automation and the investigation of industrial control for the students.


Centrifuge model tests were conducted to examine the performance of piles behind a failed excavation in clay. In these tests, the bending moment profile and pile head deflection were monitored during and after excavation. The test results revealed the behavior of pile in clay is time dependent and the development of tension cracks in the active shear failure wedge prevent the full transmission of soil pressure on the piles and hence the induced pile bending moment and deflection decrease after the failure of the retaining wall.


Norethisterone-3-methoxime was found to be more potent than norethisterone itself as an antifertility agent in the rat. This compound may prove to be valuable in attempts to develop new progestins for human use.


This paper proposes a robust international portfolio optimization model with the consideration of worst-case lower partial moment (LPM) and worst-case mean return. In our model, we assume that the distributions and the first- and second-order moments of distributions of returns of assets and exchange rates are all ambiguous. The proposed model can be reformulated into an equivalent semidefinite programming (SDP) problem, which is computationally tractable. For investigation of the performance of our model, we also give two benchmark models. The first benchmark model is a scenario-based model which uses historical observations of returns to approximate the future distributions. The second benchmark model only considers the ambiguity of distributions but does not consider the ambiguity of the first- and second-order moments of distributions. We conduct empirical experiments in a rolling forward way to evaluate the out-of-sample performances of our proposed model, the two benchmark models, and an equally weighted model using the return measures and various risk-adjusted return measures. The result shows that our model has the best performance. It verifies that investors can obtain benefits when employing the robust model and considering the ambiguity of the first- and second-order moments of distributions.


Hydroxychloroquine is often prescribed as long-term therapy for many dermatologic indications, and it may have broader benefits (e.g., preventing or


This paper describes about a method of clothing classification. The method assumes to be used for a visual function of daily assistive robots tidying up clothes in daily environment. A set of gabor filters are applied to an input image by changing its frequency and direction, and then several feature descriptors which are invariant to translation, rotation and scale are generated. Some of descriptors enables us to know the category mainly relying on its material, and also shape. Experiments using real clothing images show the effectiveness of the proposed method.


The concept of current mode track and voltage mode track soft start is presented.Their operation principles are analyzed.Three types of current mode track soft start circuits are introduced,one type of circuit based on a diode,two types of circuit based on bipolar transistor.Two new types of voltage mode track soft start circuits are also provided,one type of circuit based on feed forward capacitor and another based on an amplifier.Their operation principle,advantages and disad- vantages are also discussed.The method about selecting related parameters and some test results are given.


The paper discusses a very simple but effective way to detect the spelling mistakes in the variable names, which are very common in the development of Fortran programs and go undetected by the compiler.


Diamond-like carbon (DLC) films were deposited by a plasma source ion implantation (PSII) method on silicon wafer and 440C stainless steel substrates. Pure C/sub 2/H/sub 2/ gas was used as a working gas for plasma. The plasma was generated by an inductively coupled plasma (ICP) source with a planar coil. Two types of pulse generators connected in series were used for DLC film deposition in this study. The superposed negative voltage pulsed in the range of 3 kV to 13 kV and DC in the range of 1 kV to 4 kV were applied to a substrate holder to accelerate ions from the plasma. The surface morphology was observed by a scanning electron microscope and an atomic force microscope. The compositional and structural characterization of the films was carried out using Fourier transform infrared spectroscopy (FT-IR) and Raman spectroscopy. The hardness of the films was measured by an indentation method. The friction coefficients of the films were measured with the aid of a reciprocation sliding tester. The results showed that the all of the films were amorphous and showed typical Raman spectra of DLC films. The structure and the properties of the DLC films were changed depending on the pulse condition.


— Today, all the devices around are built with the
capacity to produce and store data in its most relevant
form. Unless and until interesting insights and data which
are meaningful can be extracted, the data stored will be of
no use. Fitness tracking smart watches like fitbit track and
store data like the number of steps walked, the quality of
sleep, heart rate (beats per minute), the number of calories
burned in a particular day and many other various
activities. From this health tracking system, the fitbit
application gathers a huge amount of data and allows us to
analyze the fitness data collected by the application. By
employing techniques like data exploration, modelling,
deploying and integrating, we will be able to arrive with
very useful insights.


Refrigerated transportation has a primary role in assuring quality and safety of perishable products. About 4 million of refrigerated vehicles run worldwide. The energy requested for the foodstuff carriage only is about 40% of the total energy consumed during the journey. Researchers have been putting their efforts in developing innovative solutions to assure an adequate products transportation with lower environmental impacts. Latent Thermal Energy Storage systems based on PCMs are a promising technology. In this work, the discharging phase of an insulated wall consisting of a polyurethane layer wrapping a second one (0.5-2 cm thick) of PCM (2-5°C melting temperature) is analysed. 2D transient simulations are run by applying a varying hourly solar irradiation of a typical summer day in Vicenza. The results reveal that the proposed design is very promising because even the smallest thickness can assure an adequate temperature inside the cell for almost the entire operation.


The eutrophication caused by nonpoint pollution is the typical water environment pollution in China's deteriorating lakes.The aim of this study is to probe the waterculturing technique of a rape by the use of artificial floating rafts so that the nutrient nutrition,such as nitrogen and phosphorus,could be extracted from the polluted water.By this approach,the lake eutrophication in the lake will be better treated while the nitrogen and phosphorus are absorbed into the rape.


The invention provides a method for updating the operational frequency of a processor. The method comprises the following steps: detecting the number of objects which touch a touch panel; updating the operational frequency of the processor according to the number of the objects which touch the touch panel; detecting the number of objects which touch the touch panel subsequently according to the updated operational frequency of the processor; and calculating the coordinates of the objects which touch the touch panel for touching the touch panel; and outputting the coordinates to a touch system.


Machine learning algorithms typically assume independent and identically distributed samples in training and at test time. Much work has shown that high-performing ML classifiers can degrade significantly and provide overly-confident, wrong classification predictions, particularly for out-of-distribution (OOD) inputs. Conditional language models (CLMs) are predominantly trained to classify the next token in an output sequence, and may suffer even worse degradation on OOD inputs as the prediction is done auto-regressively over many steps. Furthermore, the space of potential low-quality outputs is larger as arbitrary text can be generated and it is important to know when to trust the generated output. We present a highly accurate and lightweight OOD detection method for CLMs, and demonstrate its effectiveness on abstractive summarization and translation. We also show how our method can be used under the common and realistic setting of distribution shift for selective generation (analogous to selective prediction for classification) of high-quality outputs, while automatically abstaining from low-quality ones, enabling safer deployment of generative language models.


Abstract The influences of sampling method, water depth, current velocity, and substratum on two macroinvertebrate‐based biotic indices were investigated based upon 523 samples from 55 stony riffle sites on 23 New Zealand streams. A single hand‐net sample estimated the site Macroinvertebrate Community Index (MCI) within ± 15% and four replicates yielded ± 10%. Between 8 and 10 replicate Surber samples produced ± 10% precision. Quantitative MCI (QMCI) values were more variable, with 10 or 11 replicate Surber samples required for ± 10% precision. Two procedures for detection of statistically significant differences between paired MCI or QMCI values are described. The detectable difference method (equal sample sizes) is preferred for statistical reasons but a f‐test method can be used for unequal sample sizes. MCI and QMCI were relatively independent of depth, velocity, and substratum within the sampled ranges of these variables. This is a major advantage for the assessment of water pollution or enrichment u...


Attitudes and values held by legal professionals are crucial elements of legal culture. This is especially true for judges because they make the actual decisions. This chapter explores how judges understand differences and commonalities at the European Court of Human Rights. It discusses the Court's legal culture, that is, the ideals and attitudes of the judges. The personal biographies of the judges tell us a lot about the diversity at the Court. The chapter looks at the biography of the Swedish, the Cypriot, the Belgian and the Russian judges, in order to illustrate the personalities inside the Court, and their similarities and difference in terms of background. The judges differ along three dimensions: (1) political background; (2) professional and personal experiences; and (3) legal traditions and legal education.Keywords: Belgian judges; Cypriot judges; European Court of Human Rights; legal traditions; political background; professional experience; Russian judges; Swedish judges


To develope new natural substances for whitening agent, Baeckji(Angelica dahuria;BK), Seasin(Asarum sieboldii;SS). Baecjgangjam(Bombycis corpus;BGJ) and Mynkanbang(MKB) were selected and extracted by hot water and 70% EtOH, respectively. Hydrothermal and ethanolic extracts of BK, SS, BGJ and MKB were evaluated for anti-oxidative effect, tyrosinase activity, melanogenesis of B16 melanoma cells and changes in level of tyrosinase expression by using Western blotting. All hydrothermal and ethanolic extracts showed scavenging activities of free radicals against 1,1-diphenyl-2- picrylhydrazyl(DPPH) but no inhibitory effect on tyrosinase activity. Ethanolic extracts of BK, SS, and BGJ and especially highly, those of MKB inhibited production of melanin in B16 melanoma cells and were able to reduce the level of tyrosinase expression in B16 melanoma cells. These results suggest that ethanolic extracts of BK, SS, BGJ and MKB can be an effective whitening agent from natural plant.


Professor Tetsuji Uemura is a Visiting Professor in the Division of Plastic and Reconstructive Surgery at Showa University and Clinical Professor in the Division of Plastic and Reconstructive Surgery at Saga University Hospital. He is an expert in plastic surgery working to develop
 techniques and treatments for patients with diabetic food diseases, such as foot ulcers and gangrene. Although there is broad agreement regarding the existence of tarsal tunnel syndrome (TTS), there are still differences of opinion regarding its epidemiology as an etiology for foot pain and
 paresthesia, particularly in patients with diabetes. There is also still confusion regarding the best conservative treatment, timing of surgical intervention, best surgical approach, and management of recurrences. In Japan and ASEAN countries, more and more patients with diabetic foot disease
 need to have lower limb amputations due, in part, to a lack of medical specialists for diabetic foot diseases. Uemura wants to help overcome this by harnessing his interest in chronic nerve compression of the tibial nerve inside the tarsal tunnel, caused by diabetes and how this can be treated
 and prevented. Five key themes for Uemura and his fellow researchers in the Department, known as SEEDs for the Project, are: Shaping the relationship between the progression of diabetic, neuropathy and changes in foot and gait; Establishing a simple and early diagnostic method for acute infections
 that lead to amputation; Establishing the effectiveness of prophylactic foot surgery for diabetic foot lesions, especially verifying the possibility of treatment to improve the neuropathy that causes diabetic foot lesions; and Developing shoes that effectively prevent the occurrence of diabetic
 foot lesions.


A visual servoing application for automated object detection is described. This application is based on a computer vision algorithm that enables: the detection of colored objects, which are located on a conveyor pallet, the height calculation of these objects, the determination of their type, their position and orientation, in order for a SCARA robot to be able to manipulate them. The object detection algorithm developed with the help of Matlab software relies on the fact that the image segmentation operation is performed in the HSV color space. The camera calibration and the robot calibration methods used are also described.


The action learning project described tells about one primary school's journey in addressing issues of social justice and equity in relation to Aboriginal education in Australia. The setting was a new regional primary school in New South Wales, Australia. The school needed to get Aboriginal Education on the agenda, in line with the mandatory Aboriginal Education Policy. At the same time, the Prime Minister of Australia had just apologised on behalf of the government to the nation's Indigenous people for injustices of the past. This was the micro and macro context that set the scene for the action learning project, 'Action learning through Indigenous literature', that took place during term two in 2008. Social injustices of the past were addressed and young students were made aware of Aboriginal history through Indigenous children's picture books, using authentic voice as a tool. The books were written by Aboriginal people about their unique history and culture. Indigenous people in Australia have had a long battle to maintain their cultural identity while seeking to achieve equity. By understanding the strong spiritual connection Aboriginal people have with the land, and valuing the richness of their culture, the author believes that all Australians benefit.


[Extract] Maritime archaeology is arguably the most recognised of the Australianist archaeologies, having a general appeal and a popular following that are the envy of most other sub-fields. However, because much of this has come from high-profile shipwreck-oriented research and public archaeology, there is often the mistaken assumption, even by other archaeologists, that maritime archaeology is solely concerned with the investigation of shipwrecks, or is primarily a set of techniques applied to sites located underwater.


RIFT (Resin Infusion under Flexible Tool) process modelling requires accurate material data like resin viscosity, reinforcement compressibility and reinforcement permeability. During the mould closing, the compression phase and the resin flow are important stages that strongly influence the quality of the obtained parts. In RIFT process the upper mould is a formable vacuum bag: its flexibility makes the pressure field change the local compaction state of the reinforcement and so it alters the permeability. Preform compaction depends on its compressibility, that is influenced by laminate thickness: the aim of this work is to analyse the relation between them. Moreover, this analysis is carried out observing preform deformation during process condition, in fact compression is applied by vacuum bag instead of compression testing machine. firstname.lastname@example.com Keyword-Liquid Resin Infusion, RIFT, compressibility behaviour, fabric compaction


Since it has been discovered in the Kingdom of Saudi Arabia, Oil has played an important and growing role in the economy of Saudi Arabia. And because the Kingdom is a major Oil exporting country in the World, Its income level has increased manyfold. The injection of this increased income into the domestic economy created demand for new goods and services. Hence, a new pattern of consumption emerged. The reliance of the economy of Saudi Arabia on oil exports, which are oscillating in term of their value according to the continuous oscillation in the international oil prices, makes all sectors of the economy vulnerable to this volatility. And here is where the importance of this study arises. That is the objective of this study is to study the extent to which the private consumption is affected by the oscillation in the oil revenues of Saudi Arabia, in addition to some other variable. For further insight into this Problem. The case of Saudi Arabia is compared with that of the Kingdom of Bahrain because of the different size of the oil sector in these two economies. The results have pointed out that the private consumption in Saudi Arabia and the Kingdom of Bahrain is determined directly by the private income, and indirectly by the income of the oil sector. Moreover, the cointagratin analysis indicated the existence of a stable long-run relationship between oil revenue and private consumption in the case of Saudi Arabia, While such a relationship does not exist in the case of Bahrain. This reflects the gradual shift in the classification of oil revenues from a temporal income (with a limited impact on the private consumption) to a permanent income (as a significant part of the income that affects the private consumption). Thus, oil revenue fluctuations are accompanied indirectly by fluctuations in the Saudi private consumption. Moreover, the results of the impulse response function and the variance analysis have indicated that the shocks of oil revenues in Saudi Arabia play a greater role in the short term, but the money supply takes this role in the long term. But in the case of Kingdom of Bahrain, the private consumption variable occupies the first rank among the variable that explain the variance of the prediction error of the private consumption itself in the short term and long term. PDF created with pdfFactory Pro trial version www.pdffactory.com In sum, There results show the important role played by oil revenue in the fluctuations of the private consumption in Saudi Arabia compared to that


Industrial pollution and traffic emissions emit dangerous amounts of O3, NO2, VOCs and PM into environment, bringing higher incidence of morbidity and mortality in respiratory sicknesses [1]. [...]


Much of manufacturing industry is undertaking or contemplating re-engineering to survive and succeed in increasingly competitive markets. Enterprise modelling methods offer a means of understanding existing systems and facilitating the change process and should be seen as a routine part of the planning and management activity alongside other established management methods. A synthesis of the established IDEF method and an emerging IDEF3 'process description' method is proposed called IDEF0 . It is presented in the context of an 'enterprise modelling framework' and can be used to extend the scope of individual IDEF0-3 models to provide a composite behavioural view of manufacturing enterprise systems.


ABSTRACT This paper describes aspirations and contributions that grew out of a developmental cycle of design-based research (DBR) implementation conducted over a three-year project. DBR engineers new learning environments and improves learning in context whilst communicating usable knowledge for learning and teaching in complex settings. This project employed constructionism as an overarching framework, a theory of learning, teaching, and design, which supports that learning occurs more effectively when learners understand the world around them by creating meaningful artifacts that can be probed and shared. In an attempt to infuse elements of constructionism in the use of social technologies, groups of learners were assigned to construct an artifact within social technologies. The main data collection tools employed were students' and instructor's reflections, a questionnaire, semi-structured interviews and observation of groups' activity within social technologies. Such an inquiry revealed both strengths and challenges with regard to implementing DBR and reporting how designs function in real-life settings. This paper brings forward considerations related to reporting intentionally designed interventions, potentials and limitations of DBR and implications for future DBR implementations.


Hyperspectral imagery (HSI) offers numerous advantages over traditional sensing modalities with its high spectral content that allows for classification, anomaly detection, target discrimination, and change detection. However, this imaging modality produces a huge amount of data, which requires transmission, processing, and storage resources; hyperspectral compression is a viable solution to these challenges. It is well known that lossy compression of hyperspectral imagery can impact hyperspectral target detection. Here we examine lossy compressed hyperspectral imagery from data-centric and target-centric perspectives. The compression ratio (CR), root mean square error (RMSE), the signal to noise ratio (SNR), and the correlation coefficient are computed directly from the imagery and provide insight to how the imagery has been affected by the lossy compression process. With targets present in the imagery, we perform target detection with the spectral angle mapper (SAM) and adaptive coherence estimator (ACE) and evaluate the change in target detection performance by examining receiver operating characteristic (ROC) curves and the target signal-to-clutter ratio (SCR). Finally, we observe relationships between the data- and target-centric metrics for selected visible/near-infrared to shortwave infrared (VNIR/SWIR) HSI data, targets, and backgrounds that motivate potential prediction of change in target detection performance as a function of compression ratio.


PROGRAM TRENDS: Although telecommunications initiatives and the increased use of Internet-based communications are being studied in the framework of the Library of California, work is also in progress extending the use of these communications techniques across CLSA System boundaries, notably with linked systems initiatives in the Statewide Data Base program and cooperative work among CLSA Systems in a number of areas throughout the state. Those efforts will provide information on models for establishing cost effective communications, service procedures, and delivery patterns relevant to understanding the potential costs and service improvements associated with developing a Statewide Communications and Delivery Program.


This study was carried out to determine the levels of some metal including copper (Cu), chromium (Cr), cadmium (Cd) and lead (Pb) in tissues of the mollusca gastropoda limpet (Patella rustica), using the standard atomic absorption spectrometry (AAS) technique after mineralization method. These samples were collected from three different locations (Yacoub Al Mansour, Harhoura and Guy ville) of Moroccan Atlantic coast during four seasons (winter, spring, summer and autumn). The average ranges of elements concentrations measured in samples were: Yacoub Al Mansour coast (Cu: 0.462.19 μg/g; Cr: 0,60-2,21 μg/g; Cd: 0,32-1,06 μg/g and Pb: 0,47-1,30 μg/g), Harhoura coast: (Cu: 0.813.17 μg/g; Cr: 0,94-2,5 μg/g; Cd: 0,47-0,95 μg/g and Pb: 0,76-1,42 μg/g) and Guy ville coast (Cu: 1.24-4.14 μg/g; Cr: 0,87-3,98 μg/g; Cd: 0,56-1,18 μg/g and Pb: 1,08-2,13 μg/g). During all seasons and from different sampling sites, the results obtained indicate that metals concentration in Patella rustica tissues were distributed differently .


I. Energy Spectra. Thermal and Magnetic Properties of Ferromagnets and Antiferromagnets. 1. Spin Waves in Ferromagnets 568 2. Phenomenological Theory of Spin Waves 569 3. Quantization of Spin Waves 573 4. High-Frequency Properties of Ferromagnets and Ferromagnetic Resonance 575 5. Surface Impedance of Ferromagnets 579 6. Coupled Magneto-Elastic Waves. Ferro-Acoustic Resonance 581 7. Energy Spectrum of Antiferromagnets 584 8. Thermal and Magnetic Properties of Ferromagnets 588 9. Thermal and Magnetic Properties of Antiferromagnets 589 II. Interaction of Spin Waves with One Another and with Lattice Vibrations. Relaxation and Kinetic Processes (to be published in the next issue) 10. Fusing and Splitting of Spin Waves. Scattering of Spin Waves by Spin Waves 11. Interaction of Spin Waves with Phonons 12. Relaxation of the Magnetic Moment in Ferrodielectrics 13. Dispersion of Magnetic Susceptibility of Ferromagnetic Dielectrics 14. Thermal Conductivity of Ferrodielectrics


Immunization is one of the effective methods of increasing immunity for babies. The average immunization rate in Indonesia is only 72%, which is one indicator of low immunization in Indonesia. This is a shocking tragedy and should not have happened. This type of research is analytical research. This research uses a cross-sectional approach. The population and sample in this study were all mothers who had a 12-month-old baby in the Juliana Dalimunthe Tembung Clinic Area, Deli Serdang District, which amounted to 50 people. The data analysis used is bivariate. The results of the study, based on the age of the majority of respondents aged 20-30 years, as many as 29 people (58%), the majority of respondents having high school/vocational education as many as 26 people (26%), the majority of respondents being housewives as many as 24 people (48 %). Relationship between knowledge and basic immunization in infants aged 0-12 months. It can be concluded that there is a relationship between a mother's knowledge and basic immunization for infants aged 0-12 months. Based on the results of the Chi-Square test of significance (α) = 0.05, a p-value of 0.000 (<0.05) was obtained, then Ho was rejected, and Ha was accepted. It can be concluded that there is a relationship between the mother's attitude and basic immunization for infants aged 0-12 months. It is hoped that all mothers will increase their knowledge and attitudes about immunization, and it is expected that mothers who have babies immunize their babies in a health facility for the protection of their baby.


Despite the numerous applications of ACO (ant colony optimization) algorithm in optimization computation, it remains a computational bottleneck that the ACO algorithm costs too much time in order to find an optimal solution for large-scaled optimization problems. Therefore, a quickly convergent version of the ACO algorithm is presented. A novel strategy based on the dynamic pheromone updating is adopted to ensure that every ant contributes to the search during each search step. Meanwhile, a unique mutation scheme is employed to optimize the search results of each step. The computer experiments demonstrate that the proposed algorithm makes the speed of convergence hundreds of times faster than the latest improved ACO algorithm.


This paper offers a new edition of the funerary inscription of Leo, bishop of an uncertain see in Phrygia (Lysias or Otrous?). The inscription, which is thought to come from Yanikoren, is now located in Hudai Kaplicasi (Sandikli, Turkey). A palaeographical analysis and a new reading of the inscription allow us to reconcile the apparently conflicting chronological data offered by the previous editions, and to find out the correct date (February 9th, 1059 AD; 12th indiction).


Osteoporotic vertebral compression fracture is a leading cause of pain and disability for the elderly. It tends to occur more frequently as the senile population continues to increase. The traditional treatment and surgery are often poorly tolerated by the elderly. In recently years, the minimally invasive percutaneous vertebroplasty and percutaneous kyphoplasty have become common procedures to treat painful vertebral compression fractures. Percutaneous injection of bone cement or expansion of an inflatable sacculus to enlarge the compressed vertebra before the vertebral body is strengthened by cement deposition can stabilize the fracture and reduce pain. This article is to review the indications, surgical techniques, clinical results and complications for vertebroplasty and kyphoplasty in recent years.


The Round Robin (RR) CPU scheduling algorithm is a fair scheduling algorithm that gives equal time quantum to all processes. The decision on how to select the time quantum is extremely important because the time quantum has a great effect on the algorithm's performance. This paper introduces an algorithm called Improved Group Based Time Quantum with Controlled Pre-emption (IGBTQ) that further improves on the Group Based Time Quantum (GBTQ) Round Robin algorithm. This algorithm (IGBTQ) is implemented and evaluated against Classical Round Robin (RR), Dynamic Round Robin with Controlled Pre-emption (DRRCP) and Group Based Time Quantum (GBTQ) Round Robin algorithms by using Gaussian and Uniform statistical distribution functions to generate the burst times of the processes. The improved algorithm (IGBTQ) is better than the other three scheduling algorithms under consideration (RR, GBTQ and DRRCP) for systems that adopt RR CPU scheduling.


The phenomenon of religiosity is increasingly often explored by representatives of various scientific disciplines. This is particularly noticeable in the field of the psychology of religion. The issue of human religiosity have been attracting an increa sing amount of interest among Polish scholars. The present article presents the main trends illust rating the development of interest in the phenomenon of religiosity in the field of psychology. Bot h Polish and international contexts are considered. Additionally, the papers included in the spec ial issue of Roczniki Psychologiczne (Annals of Psychology ) are outlined. The special issue is devoted to the problems addressed by Polish psychologists interested in the phenomenon of human relig ios ty.


Conventional views of the relationships between music and emotion would suggest that music can be thought of as the language of the emotions; musical meaning is expressive and emotional. Similarly, in the conventional view "learning music" is associated with long and effortful training; musical expertise and the ability to acquire it is thought to be exclusive to those with talent and/or motivation, while learning to experience music—if conceptualised at all—is thought of as individual and rather contingent. Hence music education tends to split into learning to master the processes of performance, and, for those destined for the role of music consumer, learning to appreciate cultural symbols and signals: a decoupling of perception and production. There are problems with these views. There is an increasing amount of evidence from studies of infants and children that suggests that music learning is best thought of as the cultural particularisation of an inherent capacity to engage with musical behaviour and to behave musically. the apparent effortfulness that we associate with learning to produce music is difficult to square with infant and early childhood capacities actively to engage in music. Similarly, while there is increasing evidence of music as emotionally potent, there is evidence that it is meaningful in ways that are embedded in social contexts—in film, as propaganda, as an apparent tool for manipulating attitudes and behaviours—that suggest that music's meanings are not located solely in the domain of affect. If music is the language of the emotions, it is many other things as well. I shall suggest that we can begin to resolve these problems by identifying what we mean by music in contemporary western societies and how we have come to conceive of it in the terms that we do; only then can we fruitfully address ideas of emotion and learning in relation to music. For many musicologists music exists as "pure" or "absolute", music free of text and of textual meaning; music is its own autonomous domain unconnected to everyday wordly concerns. This perspective, which colours and has helped shape more popular conceptualisation of music, have their origins in nineteenth century ideas of music, themselves reactions to earlier ideas of music as expressive of sentiment or feelings. But everywhere we look and listen, in every society that we know of, we find "something-like-music". We recognise it as "music" because it seems to bear a resemblance to what we think of as music, but it often seems to be employed to do things that music does not do in our own cultural world, and it seems to have emic significances that vastly exceeds that to which we typically allow to music. However, even in Western societies music is scarcely "pure"; it is central to and embedded in religious ritual, it manifests itself as spontaneous collective behaviour in mass contexts that are recreational yet full of group significance (e.g., football matches), and musical expertise is acquired and exercised outside of formal social institutional contexts in informal and subculturally-significant ways (garage bands, rap). Music, in other words, is not an autonomous domain that is used for display, aesthetic enjoyment or entertainment; it is a potent mediator of complex social interactions. We can make sense of this in terms of a taxonomy proposed by the ethnomusicologist Thomas Turino, who distinguishes between what he terms "presentational" musics—a typical example would be the western symphonic concert— and participatory musics, involving interaction between participants who have acquired their expertise through acculturative processes and who may not think of themselves as "musical specialists" in any sense. I shall suggest that if we think of music as a participatory and communicative medium for interaction we can resolve many of the problems that arise from conceiving of music as an autonomous domain of art. I shall further suggest that conceiving of music as fundamentally participatory allows us to ascribe it a generic function across cultures and times, that of managing situations of social uncertainty; I shall outline some of the processes and attributes that inhere in interactive music that may fit it for such a function. As an interactive process, music is bound up with affect; social interaction is fundamentally affective. We can think of emotion as elicited in presentational (or Turino's other categories of high-fidelity and studio audio art) as responses to traces of social behaviours, and to characteristics of biologicallysignificant sound. As an interactive process, music appears to be acquired very much like language: informally, through exposure and active engagement. We are statistical processors, and increasing evidence shows that we can acquire the ability to make sense of even abstract patterns in pitch and


With the new health care reform step by step,hospital information construction demand for talent in a sharp increase,the lack of personnel has become the bottleneck of the hospital information.In order to speed up the pace of construction of the medical industry information,the National Medical IT Examination Management Center launched the support and guidance of the relevant departments of the Ministry of Health,Ministry of Education and Industry and Information Ministry called "National Medi cal IT skills test" personnel training project.In this paper,the current status of the health industry information in the study on the basis of our hospital to nursing students,medical letter combination of training experience,put forward a number of practical recom mendations for vocational nursing medical information technology teaching.


The sudden onset of the 2019 SARS-CoV-2 pandemic required agile development of standards and efficient validation of assays to assess prevalence of infection as well as immune responses to infection and vaccination. Leveraging their experience in HPV serology and standards, the Vaccine, Immunity and Cancer Directorate (VICD) at the Frederick National Laboratory for Cancer Research (FNCLR) pivoted to address this unmet need in SARS-Co-V2 serology clinical testing and research. This standardization effort required the collection and processing of large volumes of blood from SARS-Co-V2 infected and uninfected individuals into serum and peripheral blood mononuclear cells (PBMCs). Collaborations with specimen collection sites across the United States were established. Following qualification for anti-SARS-CoV-2 IgG and IgM levels in independent laboratories, VICD assembled reference evaluation panels, which were used to assist the FDA's performance evaluation of commercial assays submitted for EUA approval. To date, 185 different shipments of the standard or validation panel have been sent to both domestic and international labs. These materials are also available to the SARS-CoV-2 serology community for assay calibration and performance evaluation which greatly facilitates assay data harmonization. In addition, the NCI Serological Sciences Network (SeroNet) was born from this initiative and expertise, resulting in the establishment of Capacity Building Centers (CBCs) for sample collection from different healthy, cancer and immunocompromised cohorts at Mount Sinai, Arizona State University, the University of Minnesota, and Northwell Feinstein. The NCI and FNLCR simultaneously collaborated to develop a network of investigators focused on advancing research on the immune response to SARS-CoV-2 infection and vaccination among diverse and vulnerable populations, including cancer patients. Their research has resulted in over 326 peer-reviewed publications. The CBC's have enrolled patients in longitudinal studies, resulting in a centralized collection of annotated, well characterized serum, PBMCs and clinical data. Numerous cancer cohorts, but predominantly Multiple Myeloma, are included. Furthermore, technology development was supported at the CBC's. Based upon this success, the VICD in collaboration with NCI is pursuing an even more innovative effort in pandemic preparedness to establish a Center for Serology and Data Emergency Preparedness (CESDEP); a global network able to activate and pivot to address pandemic-level threats, while continuing to expand the development of immunological assays that can inform clinical decisions for cancer and other immunocompromised patients.
 Citation Format: Nancy V. Roche, Troy Kemp, Ligia Pinto, Tom Hickey. Establishment of an infrastructure for rapid pandemic response at the Frederick National Laboratory [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 2 (Clinical Trials and Late-Breaking Research); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(8_Suppl):Abstract nr LB054.


T1c, prostate-specific antigen density < 0.15 ng/mL, Gleason score ≤ 6, two or fewer cores with cancer, and ≤ 50% cancer involvement of any core. During the follow-up period the proportions of men who underwent curative intervention (p = 0.026) or had biopsy reclassification (more than 2 cores, Gleason score > 6, or > 50% cancer involvement of any core) (p < 0.001) were significantly lower in men who met very-low-risk criteria. There were also no prostate cancer deaths in this cohort of patients. The authors conclude that for carefully selected men, active surveillance limited to patients with verylow-risk cancers according to Epstein's criteria for insignificant cancer may significantly reduce the frequency of adverse outcomes.


This paper deals with the method for extracting graphics information from DXF files, in which are the NURBS curves stored. With the extracted data, the parametric formulation of the NURBS curve can be constructed. And then, we provide an algorithm for approximating arbitrary parametric curves with circular arcs. The above processing for NURBS has been applied in the lath incision machine, which makes it possible for the CNC cutter to produce complex shaped workpieces. This machine includes 3 sets of servo motors, one set of 3-axis CNC and a conventional PC. Experimental results indicate that this method is able to provide a satisfactory performance.


The present invention provides a method for processing a substrate from a specific material, wherein the material is heated by means of induction with an electric current of a relatively low frequency, wherein an electrical current of relatively high frequency is used for further processing of the material, and wherein a bias voltage is applied to the substrate.


In this paper, a compact wideband bandstop resonator in the form of open stub combination is proposed. The wideband characteristic of the proposed bandstop resonator is due to electrical coupling at the ends of the two open stubs. A stopband is approximately improved by 52% (rejection depth: -20dB) compared with the case that the end of open stub is uncombined. Proposed structure increases the skirt selectivity and elastically controls the frequency bandwidth and rejection depth.


Handicapped Adult Learner (HAL) uses Internet to achieve different kinds of learning through different types of educational experiences. This paper describes research on HAL in Internet-based courses and ways to enhance their learning.


Aiming at the problem of poor robustness of beamforming algorithms in the existing frequencyhopping system,combined with the characteristic of fast follower jamming,a beamforming algorithm for frequency-hopping based on real-time calibration for steering vector was proposed.The steering vectors were realtime calibrated with two steps in the algorithm.Firstly,apositive matrix was constructed before the fast follower jamming arriving.Then the cost function was defined by subspace theory.And the steering vector of the desired signal was real-time calibrated by using the steepest descent algorithm.Secondly,the desired signal was removed by transformation after the fast follower jamming arriving.Then the synthetic steering vector of the fast follower jamming was real-time calibrated by using the same algorithm.In addition,the algorithm was applicable to arbitrary array for frequency-hopping system.Simulation results demonstrated that the proposed scheme could provide better robust and real-time capabilities.And it could perform well in a large range of steering vector errors.


Public investment in water-based recreation facilities is made to increase the recreation potential of an area and to improve the economic resource base of the area. Estimates of the impact of one such investment on the structure of the land market and on property values were made for a rural area in Pennsylvania. The findings of the study support the general hypothesis that investment in water-based recreation facilities does significantly influence the value of rural property and the structure of the rural land market. Property characteristics and subdivision activity on surrounding properties had to be considered in addition to distance from the recreational development to measure the impact of this public investment.


The goal of the City Evolutions Project is to establish interactive systems and games to entertain users. Because of the existing variabilities in the system and potential reuse for similar systems in this domain, the software system is designed and developed in a reuse-based way, i.e. Software Product Line Engineering (SPLE). SPLE is a reuse-based software approach with reusable software assets in order to maximise software reuse. In SPLE, it is very important to maintain the requirement traceability from software family establishment to individual product derivation. In this paper, we describe our experience of applying SPLE approach in the City Evolutions project and propose an approach to enhance the requirements traceability in SPLE.


A study has been made of the traffic capacities of non-priority streams at major/minor priority junctions. Except at abnormally high major road flows the capacities depend linearly on the flow in the relevant priority streams of the major road. The relationships depend on the lane width available to the non-priority stream, the visibility T waiting drivers, the width of the major road, and, at dual-carriageway sites, on the width of central reserve. A framework of predictive equations has been developed. In addition to normal capacity prediction, methods have been developed to allow the equations to be used specifically (I) to take account of local operating conditions at overloaded existing sites, and (II) to predict the effects of changes to the geometry of existing sites.(a) (TRRL)