One of the important issues in ontology management is handling incoming updates and dealing with possible inconsistencies that they may induce. This is even more challenging in the context of a modular and distributed representation, because of the side-effects of the propagation of changes to the other connected or related ontologies. In this paper, we analyze the notion of ontology revision in a distributed ontology representation. We introduce a revision operator for distributed ontologies and show that it satisfies important postulates for knowledge base revision. In addition, based on a tableau algorithm for ALC ontologies, we propose an algorithm for applying the received changes and revising the original ontology through the proposed operator.


Zr contents of granitic rocks of the major intrusive bodies in Japan were evaluated on the Harker diagrams. The contents show three patterns as (i) increasing type, (ii) decreasing type, and (iii) decreasing after increasing type. The first type is best shown in the M-type magnetite-series of Tanzawa tonalites, which was generated in Zr-poor mafic igneous source rocks at depth, then never saturated with Zr in magmas; thus the contents increase with the crystallization. The second type is common in the ilmenite series originated in crust materials, which was saturated with Zr at the beginning of crystallization; thus the content decreases as the silica increases. In the third-type magma, Zr increases with the increasing silica content, then around 66% SiO2 starting to decease after saturation of Zr. This is most commonly seen in the magnetite-series granitoids. Thus, variation of the Zr contents in granitoids is essentially controlled by the original Zr contents of the granitic magmas in Japan. 2014年 8月 6日受付・受理.2014 年 6月 27日資源地質学会年会にて講演. *産業技術総合研究所 (Geological Survey of Japan, AIST Central 7, Higashi 1-1-1, Tsukuba, 305-8567, Japan)


Motor nuclei and primary afferent projections of branchial cranial nerves were shown with the CoCl2 staining technique. Motor nuclei constitute a discontinuous column at the ventrolateral margin of the gray matter. The size of motoneurons decreases in the orocaudal direction within the column. The dendrites assemble in two main directions forming a dorsomedial and a ventrolateral dendritic array. The axons originate in the ventrolateral dendrites and run straight to the motor roots. Preganglionic vegetative neurons were found in a separate group at the level of the abducens nucleus, and intermingled with motoneurons at the level of the glossopharyngeus and vagus nuclei. Their axons join the visceral sensory roots of the respective nerve.


pounds invested in buying and using electronic fetal monitoring equipment over the past quarter century is one trial reported in 1993. This raises very serious questions about the returns on investment in research in this field, in which the department in which Gardosi works has received hundreds of thousands of pounds in government grants. I invite Gardosi to describe more clearly what he means by 'independent peer review.'


Studies were conducted on mass spectrometer used to measure the appearance potential. Next, mass spectra of saturated and unsaturated hydrocarbons, from C1 to C5 was measured within the electronic energy range of appearence potential to 80V, and data regarding the development of mass spectra was obtained. Furthermore, the ionization potential for the aforementioned hydrocarbons were measured and its precision studied.


The panic of the alcoholic who has hit bottom is the panic of the man who thought he had control over a vehicle but suddenly finds that the vehicle can run away with him. Suddenly, pressure on what he knows is the brake seems to make the vehicle go faster. It is the panic of discovering that it (the system, self plus vehicle) is bigger than he is.... He has bankrupted the epistemology of "self-control."


The 9th Annual Conference of the International Society for Quality of Life Research (ISOQOL) addressed state-ofthe-art methods and theoretical models for measuring health-related quality of life (HRQOL) and focused on opportunities for the use of these tools within practical settings and circumstances. The scientific program was chaired by Carolyn Schwartz (University of Massachusetts Medical School, MA, USA) and Jeff Sloan (Mayo Clinic, MN, USA). A variety of topics were addressed at the conference – chief among them were: • End-of-life issues • Chronic illness • The clinical significance and interpretation of research findings • Response shift • Adherence to therapy HRQOL at the end of life is a topic that does not ordinarily receive the attention it deserves. During the first plenary session, Tom Hack (CancerCare Manitoba, Canada) presented the results of a qualitative study through which the construct 'dignity' was operationalized and assessed. His approach to qualitative research, using innovative methodology undertaken with cancer patients receiving palliative care, was engaging and practical. At the same session, remarks provided by Carol Tishelman (Karolinska Institutet, Sweden) that focused on how to add precision to qualitative research were well received by the audience. The end-of-life issue received further attention at the conference during a special symposium chaired by Carolyn Schwartz. In the symposium, research was presented that ranged from new tools developed specifically for a seriously ill and/or dying population, to measuring the treatment preferences for those receiving end-of-life care. The end-of-life period and the issues raised by it are relevant for exploration by HRQOL research because the field has a natural relationship with chronic illness, regardless of whether the illness is in remission or is progressing. As is always the case at ISOQOL annual conferences, chronic illnesses of all sizes and shapes were fodder for HRQOL presentations. Topics that received special attention at one such session, chaired by Jane Scott (Mapi Values USA, NC, USA), included examination of models to accurately reflect the multidimensional nature of HRQOL assessment, using data from patients with AIDS, the psychological impact of cancer and treatment for it and how this relates to posttraumatic stress disorders, the relationship between HRQOL findings in patients with multiple sclerosis and other chronic neurological illnesses, HRQOL findings in cancer survivor patients and the interrelationships between pain, mental and physical health and HRQOL in people living with HIV infection. As the poster and oral research presented at the conference indicated, there is much interest in the development of more robust and precise instruments based on item banks and other state-of-the-art methodology. Computer-adapted testing, for example, has allowed researchers to develop instruments that require only a few items. However, due to the fact that each person's response is dynamically matched to the best estimate of their level of health, these types of approaches result in shorter administration time, producing a final score that is practically identical in value and reliability to longer instruments which must be completed in their entirety to be effectively scored and interpreted. A debate regarding the pros and cons of computer-adaptive testing was moderated by David Osoba (QOL Consulting, Canada) during the conference. Three oral sessions were devoted to cancer. The papers presented and the issues discussed within one of these sessions included the use of QoL as a primary end-point within a lung cancer study. The paper, offered by Andrea Bezjak (Princess Margaret Hospital, Canada), was innovative because the successful use of HRQOL as a primary end-point was conducted within an international clinical study. Other noteworthy topics presented within this session, chaired by Galina Velikova (St James's University Hospital, UK), included insights into:


The unique physicochemical properties of multi‐walled carbon nanotubes (MWCNT) present potential risks to physiological systems. We report here that an acute pulmonary instillation of MWCNT negatively impacts coronary flow (4.9 ± 0.6 ml/min/g vs. 6.8 ± 0.6 ml/min/g in vehicles) during reperfusion of isolated rat hearts subjected to global ischemia/reperfusion (I/R) injury. We hypothesized that MWCNT exposure blunts relaxation responses of vascular tissues. Male Sprague‐Dawley rats were exposed to 100 μg of MWCNT suspended in 10% surfactant/saline (10%SS) or the vehicle only. 24 hours later, segments of the left anterior descending (LAD) coronary and thoracic aorta were mounted on a multi‐myograph system. The segments were subjected to cumulative doses of acetylcholine (ACH), sodium nitroprusside (SNP), serotonin (5‐HT), or endothelin 1 (ET‐1). The LAD constrictor responses of the MWCNT group generated a greater magnitude of active stress (mN/mm2) to ET‐1 (4.03 ± 0.41 vs. 2.62 ± 0.23) and 5‐HT (3.76 ± 1.20 vs. 0.88 ± 0.34) compared to vehicle. Hillslope comparisons between groups revealed depressed aortic responses to ACH (−0.69 ± 0.23 vs. −1.95 ± 0.23) and ET‐1 (1.08 ± 0.09 vs. 1.74 ± 0.21) in the MWCNT group. From these data we conclude that an acute exposure to MWCNT can be deleterious to vascular reactivity and increases risks for cardiac injury. Supported by NIH ES019311 (JMB) & ES016246 (CJW).


With the culture in the construction of the execution of the waterproofing in the absence of a specific project, being executed from empirical knowledge and being in most cases the villain of the pathological manifestations. Over time, the great experts have been modifying this scenario since the creation of the NB-279, which served as a base text and the Brazilian Institute of Waterproofing (IBI) has been modernizing waterproofing techniques. And with the creation in ABNT NBR 9575 – Waterproofing – Selection of Waterproofing in October 2003, this panora changed positively. Where the professionals have as support regulated techniques with support for the formulation of specific projects thus being increasingly requested in various types of enterprises. In this work the importance of a specific project and various type of waterproofing systems will be presented, as the correct techniques for their execution. For better understanding, case studies of works with pathological manifestations and proposals for their solution are presented. It will be approached in the form of research, the current panorama of the effective use of specific projects.


Mental emotional problems at adolescence if not addressed early on can increase the risk of the occurrence of mental disorders. This research aims to know the influence of supportive therapies against mental emotional problems of teenagers. Research conducted at Private Vocational High School of City "X". Design of  research  is Quasy Experimental Pre-Post Test With the Control Group, the sample numbered 108 teens, with the total sampling techniques. 54 the respondent is the intervention group and the 54 respondents again into the control group. The instruments used in this study is questionnaire SDQ (Strengths and Difficulties Questionnaire), module, the workbook, as well as supportive therapy evaluation book groups. Statistical tests are used  test t-independent. The research results obtained of a range of mental emotional problems of adolescents in the intervention group prior to the granting of a therapy that is mean: 17,00. After administering therapy obtained the mean: 13, 3. The results meaning that there is a difference of meaning between the emotional mental issues have been given supportive therapy group treatment. The advice of this research is to apply a group of supportive therapy as one therapy to overcome the emotional mental problem experienced by teenagers.


The article presents the examples of ethical attitudes in the actions and the enterprisingattitudes in the field of road safety.Ethical attitudes in business were discussed in reference to the example of education systemof traffic safety. As the illustration of ethical attitudes in the education actions of WojewodzkiOœrodek Ruchu Drogowego and the private centers and association of drivers training werediscussed.The chosen questions of ethics in construction trade and motorway services also werementioned. In the article, the chosen indicators of road accidents in Poland and in EuropeanUnion in years 2005–2006 and firs half on 2007, were presented and compared.


Fast-forward interplanetary interplanetary shocks, as occur at the forefront of interplanetary coronal mass ejections and at corotating interaction regions, can rapidly compress the magnetopause inside the drift paths of electrons and protons, and expose geosynchonous satellites directly to the solar wind.  Here, we use Gorgon Global-MHD simulations to study the response of the magnetopause to different fast-forward interplanetary shocks, with strengths extending from the median shocks observed during solar minimum up to that representing an extreme space weather event. The subsequent magnetopause response can be characterised by three distinct phases; an initial acceleration as inertial forces are overcome, a rapid compression well-represented by a power law, and large-scale damped oscillatory motion of the order of an Earth radius, prior to reaching pressure-balance equilibrium. The subsolar magnetopause is found to oscillate with notable frequencies in the range of 2–13 mHz over several periods of diminishing amplitudes.  These results provide an explanation for similar large-scale magnetopause oscillations observed previously during the extreme events of August 1972 and March 1991 and highlight why static magnetopause models break down during periods of strong solar wind driving.


Humans and the environment are two elements that should coexist. All levels of society should own related awareness of maintaining the environment. However, in reality, the river border community's awareness of the importance of preserving the environment is still lacking. One of the triggering factors is the lack of public legal awareness about the environment. the Green Constitution echoes the regulation of human rights to the environment in the state constitution as a commitment to environmental protection and management. The purpose of this activity is to foster an understanding of the legal awareness of the river coast community about the environment, understanding of regulations or alternative environmental policies on the river coast, and the community's ability as a pioneer of environmental law. The research method used in this study is using a qualitative approach. Data collection techniques by participant observation and focus groups discussion. Data analysis techniques with qualitative descriptive analysis techniques. The expected outcome is that the residents of the riverbank communities will gain advanced knowledge and understanding of legal awareness to protect the environment through the Green Constitutions program.


The decorum of the moderns, generally implied rather than ex pressed — for the word itself is now considered indecorous — has condemned or refused to take seriously much that was sanctioned by ancient and Renaissance writers and painters. If we are to approach these works with the sympathetic understanding they deserve, we have to respond to them with a sense of the decorum which they respect and which no longer obtains in the modern world. My examples — and this paper is no more than a plea for what needs to be done for the sake of some great works of art — will be confined to the Venus and Adonis of Shakespeare and its parallels in the visual


Preprocessing data for research, like finding, accessing, unifying or converting, takes up to large parts of research time spans (Wittenburg and Strawn 2018). The FAIR (Findability, Accessibility, Interoperability, Reusability) principles (Wilkinson 2016) aim to support and facilitate the (re)use of data, and will contribute to alleviating this problem. A FAIR Digital Object (FAIR DO) captures research data resources of all kinds (raw data, metadata, software, ...) in order to align them with the FAIR principles.
 FAIR Digital Objects are expressive, machine-actionable pointers to research data (De Smedt et al. 2020). As such, each FAIR DO points to one research data object. Additionally, they may link to other FAIR DOs, explaining their relations. The FAIR Digital Object Lab (Pfeil et al. 2022) is an extendable and adjustable architecture (a software stack) for generic FAIR Digital Object tasks. It consists of a set of interacting components with services and tools for creation, validation, discovery, curation, and more. In this talk, we will present our plans for the FAIR DO Lab and explain our decisions, which are mostly based on the experience gained in previous developments.
 The creation and maintenance of FAIR DOs is not trivial, as their persistent identifiers (PIDs) contain typed record information. When creating or maintaining PID records of FAIR DOs, the required information has to be validated, involving calls to a public Data Type Registry (DTR) (Lannom et al. 2015). After a successful validation, the information has to be transformed to a representation of a PID service. After a FAIR DO has been registered successfully, the PID should be documented locally and disseminated. Using these PIDs as a starting point, tools may use the machine-actionability of FAIR DOs to maintain search indexes or to create collections. This enables researchers to look up PIDs by searching for record information or timestamp.
 We are developing a set of services, offering a solution to support these use-cases, which we call the FAIR DO Lab. Its goal is to have a production-ready and configurable software stack, easing the development of FAIR-DO-aware tools and services by offering at least the described use-cases. We have already gained some experience by its predecessor, the FAIR DO Testbed (Pfeil et al. (2021a)), which was introduced at the Research Data Alliance (RDA) Virtual Plenary 17 Poster Session (Pfeil et al. 2021b). The Lab will be configurable similar to the Testbed, as each service can be omitted or replaced to satisfy specific needs while integrating the Lab on top of existing research infrastructures.
 The FAIR DO Lab enables PID record management and validation using the Typed PID Maker (Pfeil and Jejkal 2021), following the RDA PID Information Types (PIT) Working Group Recommendations (Weigel et al. 2015) and an external Data Type Registry (DTR), following the RDA Data Type Registry Working Group Recommendations (Lannom et al. 2015). The DTR stores profiles and types, enabling typed, machine-actionable PID records. The Typed PID Maker uses this information for the validation of PID records, and stores and disseminates PIDs after their creation.
 All created or modified PIDs are communicated to a message broker. This way, other services can be notified about such activities. Our first service making use of this will be an advanced indexing service. It will ingest the PIDs and their record information into a search index, but also try to extract information from the bit-sequence of the digital object itself. In a second step, we are considering the automated creation of collections utilizing our production-ready Collection Registry (Chelbi and Jejkal 2020), which the Testbed already includes. This will require a set of rules and a process to use those rules in order to place new PIDs in the correct collection. The Collection Registry is an implementation of the Collection API specification (Weigel et al. 2017), which was published by the corresponding RDA Research Data Collections Working Group.
 On the conceptual side, we hope to gain more insight about the required structure of PID records. There are ongoing discussions about this structure and to which degree standardization is required. Large talking points are the concepts of Digital Object Types (Lannom et al. 2015) and Kernel Information Profiles (Weigel et al. 2018). Working on the Lab and its predecessor, we recognized that there are large gaps regarding the structure of FAIR Digital Objects and the roles of the object types and profiles. To bring FAIR DOs into reality, research software will need to use them. But as FAIR DOs point to diverse kinds of research data, the software needs to make decisions. To what extent can the software use a specific FAIR DO? We observed that too much flexibility makes automated decisions harder. Our suggestion is therefore to consider FAIR DOs less from the infrastructure point of view, and more from the machine's point of view to improve the machine-actionability. We expect that we will gain insights about the feasibility in the development process to ease the development of further FAIR-aware tools for research, particularly for specialized tools that already exist and are in use. It will not be feasible to write every tool from scratch.
 On the practical side, the Lab will already have a stronger focus on interactive tools with user interfaces in order to provide an easy-to-use Lab for research. We consider our current work on granular base services for research data management to be a solid ground for such developments. These tools can of course not replace specialized tools, but will make the generic services in the Lab easy to use. We still expect that specialized tools will benefit from the integration of such services.
 The FAIR DO Lab development has been supported by the research program 'Engineering Digital Futures' of the Helmholtz Association of German Research Centers and the Helmholtz Metadata Collaboration Platform.


The bentonite loaded titanium oxide photocatalyst was prepared by sol-gel method with tetrabutyl titanate as raw materials,and the phtotdegradation performance of photocatalyst was determined by spectrophotometry,and the main factors of effect on photodegradation of phenol were discussed.The degradation rate reached 98.2% when the value of pH was 8.0,the dosage of photocatalyst was 15mg/L,and the concentration of phenol was 5mg/L,with the illumination time of 120min.


being thorough and "thick," perhaps at times redundant but never inaccessible or uninformative. Through successful projects like the Hammarby Sjostat eco-district in Stockholm and Oslo's Aker Brygge and Vulkan new districts, Scandinavian designers and planners are opening up to the world, sharing the lessons they have learned, and inspiring us with their enlightened pragmatism. In the world of sustainable urban design and planning Scandinavia is emerging as a place of experimentation and innovation, leading the way designing with nature tomorrow's green urbanism. Now let's return to the question: "Is Oslo a biophilic city?" After reading this book, one can certainly affirm that it is very close to becoming one. Oslo's unique environmental history has placed the city in a position of clear advantage over other cities. The story of Oslo shows that by making well-thought-out, courageous decisions like the creation of a park system at the end of the 1800s, the introduction of a congestion toll downtown, or the long-term commitment compactness, have helped the city achieve important goals related to air quality, access to nature, and livability and lay important stepping stones toward biophilia.


This paper presents the results of an experimental study conducted to understand the behavior and stress-transfer mechanism of fiber-reinforced cementitious matrix (FRCM) composites externally bonded to a concrete substrate for strengthening applications. The FRCM composite was comprised of a polyparaphenylene benzobisoxazole (PBO) fiber net embedded within two layers of polymer-modified cement-based mortar. Single-lap shear tests were conducted on specimens with composite strips bonded to concrete prisms. Parameters that varied were bonded length and width of composite. Additionally, the external coating layer of matrix was omitted on a limited number of specimens to examine the interfacial behavior between fibers and matrix and the role of the matrix in the stress transfer. Strain measurements along the composite bonded length were used to investigate the stress-transfer mechanism. Results suggest that the effective bond length of this composite is within the range of 250 to 330 mm (10 to 13 in.). Unlike with fiber-reinforced polymer (FRP) composites, no width effect was observed in terms of the maximum load. Finally, the stress-transfer mechanism at the matrix-fiber interfaces on either side of the fiber net was found to be unequal.


Descartes is an executable specification language that supports the rapid prototyping of partial through complete software specifications. A technique developed to represent Descartes executable specifications visually by adapting the charts of I. Nassi and B. Shneiderman (1973), is described. Symbols are identified for the data structuring methods and the rationale for selecting these symbols is discussed. The benefits gained in moving a graphical technique up to the front end of the software life cycle are discussed. Sample specifications are included to illustrate the effectiveness of the technique.<<ETX>>


Both cytosolic (c‐AAT) and mitochondrial (m‐AAT) isozymes of aspartate aminotransferase (EC 188.8.131.52) appear in serum in some diseases including hepatobiliary dysfunction. The present study aimed at elucidation of the mechanism by which AAT isozymes are cleared from blood. Intravenous injection into rats of m‐AAT and c‐AAT purified from rat liver exhibited a biphasic clearance curve with an overall half‐life of 42 min and 4.7 hr, respectively. The tissue distribution of the radioactivity following intravenous administration of 125I‐labeled isozymes revealed that the liver is a major organ involved in plasma clearance of these isozymes. This conclusion was also supported by the significant retardation in plasma clearance of m‐AAT in hepatectomized as well as CCI4‐intoxicated rats. Furthermore, clearance rate of each AAT isozyme in an isolated perfused liver exhibited a single exponential process with the uptake rate for m‐AAT being much faster than that for c‐AAT.


Abstract A fresh-water planarian collected in Anatolia is described. Its major characteristic concerns the copulatory system which exhibits features shared by the maricolan species. As only one specimen was available for diagnosis it is not advisable to infer its taxonomic position within the Tricladida. However, this is not the first case of a planarian which, though living in a fresh-water habitat, presents morphological characters common to the maricolan species.


Thank you for downloading movie making a guide to film production. As you may know, people have look hundreds times for their chosen novels like this movie making a guide to film production, but end up in harmful downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they juggled with some infectious virus inside their computer. movie making a guide to film production is available in our book collection an online access to it is set as public so you can get it instantly. Our digital library saves in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the movie making a guide to film production is universally compatible with any devices to read.


Discovery of nanometallic Cu0 with Fe0 in the human brain will fundamentally boost our understanding of neurobiology. The chemistry of copper and iron plays a critical role in normal brain function. A variety of enzymes and proteins containing positively charged Cu+, Cu2+, Fe2+, and Fe3+ control key processes, catalyzing oxidative metabolism and neurotransmitter and neuropeptide production. Here, we report the discovery of elemental (zero–oxidation state) metallic Cu0 accompanying ferromagnetic elemental Fe0 in the human brain. These nanoscale biometal deposits were identified within amyloid plaque cores isolated from Alzheimer's disease subjects, using synchrotron x-ray spectromicroscopy. The surfaces of nanodeposits of metallic copper and iron are highly reactive, with distinctly different chemical and magnetic properties from their predominant oxide counterparts. The discovery of metals in their elemental form in the brain raises new questions regarding their generation and their role in neurochemistry, neurobiology, and the etiology of neurodegenerative disease.


The performance of a wireless communication system depends on amplifier's nonlinearity. In this paper, Feed-forward amplifier implementation for wideband communication system are introduced. By adding a new distortion cancellation loop to the original feedforward structure, improved measurement for large linearity power output is presented. The intermodulation distortion (IMD) for two tone harmonic balance has been reduced to −90.5 dBm. A UMTS downlink channel has been used as application case.


Organizational and technological changes tend to accelerate the reallocation of labor. But more specifically, what do we know of the relationship between the type of change and the nature of the breach of contract work (economic redundancy, dismissal on personal grounds or resignation)? The paper relies upon both quantitative and qualitative data. The quantitative data come from a French matched employer-employee survey, the 2006 Organisational Change and Computerisation survey. The qualitative part draws on thirty interviews with employees who had left their firm. It shows that while significant links can be identified between types of change and the break up, termination appears in all cases as a way to "exit", i.e. to escape the degradation of working conditions and the loss of valuable job features.


The study assessed the ferry operation under the existing fare structure and identified potential fare and operational models that could be applied or adapted to the Western Isles ferry routes. Recommendations were made on the most effective ferry fare mechanism and operational models for stimulating economic growth and social stability in the Western Isles.


A new laser-induced fluorescence spectrum of lithium vapor in the range of 500~600nm pumped by XeF (351.1nm)and N_2(337.1nm)UV lasers with He and Ar as buffer gases is reported and analyzed. The upper and lower energy levels to produce the new emission spectra are discussed primarily. The potential kinetic process in the lithium vapor is given. Four superfluorescence lines are reported.


A very stiff six-component wind tunnel balance of simple construction was produced with semiconductor strain gauges on the axial-load element and with a temperature sensor installed. Thermocompensation was performed by software, treating the temperature sensor as the seventh balance load component. Calibration of the prototype validated the concept.


Let {4n } be an orthonormal set in L2 [0, 1], n having finite total variation Vn. Haar proved [1] that lim Vtn = co and that consequently On } has an intrinsic ordering according to nondecreasing total variation. He showed, in fact, that in this ordering Vtn > cV/n where c is an absolute constant. A different proof was later given by Rudin [2]. We present a short proof that lim Vn = ?? under a much weaker hypothesis than orthonormality.


Substantial evidence shows that tumor suppressor WW domain‐containing oxidoreductase, designated WWOX, FOR or WOX1, is involved in neurodegenerative diseases, neural disorders, cancer progression, and metabolic diseases. WWOX protects neurons from degeneration by binding tau and tau‐hyperphosphorylating enzymes GSK3β, ERK, and JNK1, and promotes neuronal differentiation. WWOX is frequently downregulated in the hippocampi of patients with Alzheimer's disease (AD). Indeed, WWOX may start to downregulate in the cortex and hippocampus in mid‐aged normal individuals. Both in vivo and in vitro evidence show that upon WWOX downregulation, a cascade of protein aggregation occurs, involving spontaneous relocation of TRAPPC6AΔ (trafficking protein particle complex 6A delta, TPC6AΔ) and TGFβ1‐induced anti‐apoptotic factor 1 (TIAF1) to the mitochondria. TPC6AΔ aggregates first and then TIAF1, followed by activating caspases and leading to amyloid precursor protein (APP) degradation and formation of amyloid beta (Aβ) plaques and tau tangles. Here we identified SH3GLB2 (SH3‐Domain GRB2‐Like Endophilin B2 ), whose aggregation is downstream that of TIAF1. The aggregates can be found in the AD hippocampi. A 31‐amino‐acid protein Zfra is highly effective in blocking and preventing the aggregation of TPC6AΔ, TIAF1, SH3GLB2, Aβ, and Tau. To characterize how the BAR domain‐containing SH3GLB2 aggregates, here we show that alteration of Tyr77 to Phe77 abolishes TGF‐β‐mediated polymerization, suggesting that Tyr77 phosphorylation is needed for SH3GLB2 aggregation. Activation of p53 by PRIMA‐1 abolishes SH3GLB2 aggregation, whereas inhibition of p53 activation by Pifithrin‐μ induces the aggregation. Induction of autophagy by thapsigargin accelerates SH3GLB2 aggregation. Transiently overexpressed SH3GLB2 causes apoptosis. Neurotoxin MPP+ induces neuronal death in vivo due in part to SH3GLB2 aggregation. Tumor suppressors p53 and WWOX are partners in cancer suppression. Loss of WWOX causes p53 instability. Conceivably, dysregulation of both p53 and WWOX results in initiation of the TPC6AΔ/TIAF1/SH3GLB2 aggregation cascade and leading to the formation of Aβ plaques and tau tangles of the neurodegeneration pathway.


fourth day after tillage, and then declined in the tilled soil. Tilled soil showed increases in MBN, nitrate, and denitrification rates, suggesting although tillage can increase the efflux of CO2 from that tillage makes available previously protected organic N. The over- the soil surface, it may not always stimulate microbial all reduction in respiration together with the lack of response in activity. Degassing of dissolved CO2 from the soil soluMBC, however, suggests that tillage did not make available significant tion and pore space upon soil disturbance and aeration amounts of readily decomposable C. These combined C and N dynam- may partially explain the temporary efflux of CO2 after ics suggest that low C/N ratio compounds may have been mineralized tillage (Reicosky et al., 1997). following tillage. Denitrification rates increased in the tilled soil even Changes in microbial activity and nutrient pools may though the bulk of the soil had reduced respiration and bulk density. be associated with simultaneous changes in microbial Tillage caused temporary changes in PLFA profiles, suggesting community structure. Analysis of PLFA is a useful assay changes in soil microbial community structure. Phospholipid fatty because (i) the concentration of total PLFA can be used acid 18:1 v7t, which marks the presence of eubacteria, decreased in the tilled soil. In contrast, 19:0 cy, a marker for anaerobic eubacteria, as an index of viable microbial biomass since phosphoincreased in the tilled soil. Our results show that tillage causes short- lipids are rapidly degraded after cell death, (ii) multivarterm changes in nutrient dynamics that may potentially result in N iate analysis of the PLFA profiles can be used to detect losses through denitrification and nitrate leaching, as well as C losses changes in community composition, and (iii) certain through degassing of dissolved CO2. These changes are accompanied fatty acids may be used as molecular markers for specific by concomitant shifts in microbial community structure, suggesting a taxa and as indicators of microbial stress (Bossio and possible relationship between microbial composition and ecosystem Scow, 1995; White et al., 1996; Vestal and White, 1989). function. The complex interactions between C and N dynamics, microbial activity, and CO2 efflux after tillage deserve further investigation. The purpose of this research was


It is known that functional binding sites in the carboxyl-terminus of the hepatocyte growth factor (HGF) receptor, c-Met, are required to bind growth factor receptor bound protein 2 (Grb2) and transduce the motility and proliferation response to HGF. Downstream targets coupled to the Src homology 3 (SH3) domains of Grb2 following HGF stimulation are only partly known. A recent finding that approximately 50% of the endogenous Grb2 is localised within the detergent-insoluble (cytoskeletal) fraction of A431 epidermoid carcinoma cells, implied that Grb2 may link receptor tyrosine kinase signals to the cytoskeleton. Therefore Grb2 may be involved in cytoskeletal rearrangement during cell motility and invasion. The significance of Grb2 SH3 domains in driving the cellular phenotype in response to HGF was investigated in cell lines expressing the HGF receptor and transfected with wild-type and dominant-negative constructs lacking the Grb2 SH3 domains. High apoptotic rates of cell transfections have implied that the SH3 domains of Grb2 are able to sequester phosphoinositide kinases (PI3-Kinase), which is also responsible for cell motility downstream of Met, presumably through formation of a protein multicomplex, and therefore inactivate or partly inhibit the protein kinase B (PKB)/Akt survival pathway. Recent evidence suggests Grb2 involvment in survival pathways by formation of protein multicomplexes. Therefore the involvment of Grb2 in a survival pathway through sequestering of PI3-Kinase or Cbl-PI3-Kinase from a Src/Cbl/PI3-Kinase complex able to activate PKB/Akt is hypothesized and discussed.


The objective of the subtask is to derive a model to evaluate the luminance distribution of the sky vault on the basis of Meteosat data. This information is a key element in the field of building energy saving, it is the basis of indoor daylight calculation. Evaluation programs like Genelux (LASH-ENTPE) need this sky luminance distribution to perform their calculations. Sky luminance distribution models have been developed in the last years on the basis of horizontal diffuse illuminance. Their precision depends on the input data and these models cannot take into account the statistical cloud distribution in the sky vault. Perez et al. tried to superpose a statistical cloud distribution on their symmetrical model, but this was done on a unique set of data and a particular site. The model was not tested on other data (due to the lack of clean and complete sky luminance distribution database) and therefore cannot be used in any site by now without a question mark on the results.


Provided are a bovine lung enoxaparin sodium, a preparation method therefor, and an application thereof. The bovine lung enoxaparin sodium is prepared from bovine lung heparin, and the content of ΔUA2S-GlcNS6S(ΔⅠS) is up to 75% to 83%, while the content of the ΔⅠS in (bovine intestinal mucosa) enoxaparin sodium, sheep intestinal mucosa enoxaparin sodium, and bovine lung enoxaparin sodium is respectively 58% to 66%, 64% to 72%, and 50% to 58% only. The biological anticoagulant activity, anti-Xa, anti-Ⅱa, the ratio between the anti-Xa and the anti-Ⅱa, and other physiochemical properties of the bovine lung enoxaparin sodium all meet the release criteria of the current pharmacopeia to enoxaparin sodium. Also provided are two types of bovine lung enoxaparin sodium injections, preparation methods therefor, and applications in anticoagulation experiments inside animals.


VOLUME ONE Preface Book 1 - Concerning the Constitution of Human Nature, and the Supreme Good 1. Of the Constitution of Human Nature and its Powers and first, the Understanding, Will, and Passions 2. Concerning the finer Powers of Perception 3. Concerning the Ultimate Determinations of Will, and benevolent Affections. 4. Concerning the Moral Sense, or Faculty of perceiving Moral Excellence, and its Supreme Objects 5. The Sense of Honour and Shame explained. The universal Influence of the Moral Sense, and that of honour and their Uniformity. Book 1. Part 2 - An Enquiry into the Supreme Happiness of Mankind 6. How far into the Supreme Sensations, Appetites, Passions and Affections, are in our Power 7. A Comparison of the several sorts of Enjoyment, and the opposite sorts of Uneasiness, to find their importance to Happiness 8. A Comparison of the several Tempers and Characters in point of Happiness or Misery 9. The Duties toward God and first, of just Sentiments concerning his Nature 10. The Affections, Duty, and Worship, to be exercised toward the Deity 11. The Conclusion of this Book, showing the way to the Supreme Happiness of our Nature Book 2 - Containing a Deduction of the more special Laws of Nature, and Duties of Life, previous to Civil Government, and other adventitious States 1. The Circumstances which increase or diminish the Moral Good or Evil of Actions 2. General Rules of Judging about the Morality of Actions, from the Affections exciting them, or opposing them 3. The general Notions of Rights and Laws explained with their Divisions 4. The different States of Men. The State of Liberty not a State of War. The way that private Rights are known. The Necessity of a Social Life 5. The private Rights of Men first, such as are called Natural and the Equality of Men 6. The adventitious Rights, real, and personal. Property or Dominion 7. The Means of acquiring Property. How far it extends. In what Subjects it resides 8. Concerning derived Property, and the Ways of alienating or transferring it 9. Concerning Contracts or Covenants 10. The Obligations in the Use of Speech 11. Concerning Oaths and Vows 12. The Values of Goods in Commerce, and the Nature of Coin 13. The principal Contracts in a Social Life 14. Personal Rights arising from some Actions of the Person obliged, or of him who has the Right 15. The Rights arising from Injuries and Damages, done by others: and the Abolition of Rights 16. Concerning the general Rights of Human Society, or Mankind as a System 17. The extraordinary Rights arising from some singular Necessity 18. How Controversies should be decided in Natural Liberty Book 3 - Of Civil Policy 1. Concerning the adventitious States or permanent Relations: and first, Marriage 2. The Rights and Duties of Parents and Children 3. The Duties and Rights of Masters and Servants 4. The Motives to constitute Civil Government 5. The natural Method of constituting Civil Government, and the essential parts of it 6. The several Forms of Polity, with their principal Advantages and Disadvantages 7. The Rights of Governors, how far they extend 8. The Ways in which Supreme Power is acquired: how far just 9. Of the Nature of Civil Laws and their Execution 10. The Laws of Peace and War 11. The Duration of the Politic Union and the Conclusion.


This paper examines the impact of eight firm - specific determinants of corporate capital structure or financial leverage - firm size, tangibility, growth opportunities, profitability, non - debt tax shields, operating risk, liquidity and firm age - over the entire conditional distribution of leverage through the application of quantile regression methodology on a balanced panel data related to a selected sample of 76 Indian pharmaceutical companies listed on the Bombay Stock Exchange over a period of 10 years from 2002-03 to 2011-12. The coefficients of the explanatory variables are estimated at five quantiles, namely, 5th, 25th, 50th, 75th and 95th. The empirical results indicate marked non-linearities in the relationships between leverage and its firm-specific determinants with the estimated regression coefficients of the explanatory variables changing magnitudes and statistical significance accompanied by change of signs (in some cases) at different quantiles. This study, though limited to a particular industry, is primarily an attempt to affirm the existence of non-linearities in capital structure determinants of corporate firms in the Indian scenario.


In this paper,the study objects are the 24~26th Olympic games.With the methods of literature, statistics and induction, the strength dimension, country dimension and sports event dimension of competition state of the contemporary summer Olympic games are discussed with a view to supplying reference for national Olympic Program.


Imitation poses a unique problem in determining the pattern of motor activation that will make actions look like a connection of hidden states. Often any movement requires complex set of mechanisms that map an activation of motor representation by movement observation. This imitation capacity depends on learned perceptual-motor correspondence. We propose Gesture Imitation Learning through hypernetworks approach for human-machine interaction. Hypernetwork model provides dynamic and versatile connectivity ideal for robust multimodal learning.


ABSTRACT Throughout history, humans have told stories to one another. Although these stories have largely disappeared over the course of time, they have sometimes left material remains, for instance in the form of rock art. However, rock art might not be the only materialization of prehistoric storytelling practices. On the contrary, if made active again, other prehistoric artefacts might also bring past storytelling practices back to life. In this paper, we examine how storytelling might have taken place in Late Mesolithic Finland (c. 6800–5200 cal BCE). As a case study, we investigate a zoomorphic wild reindeer (Rangifer tarandus) antler artefact from southern Finland, the so-called 'Lepaa artefact', with multidisciplinary methods arising from the traditions of experimental archaeology, 3D technologies, and artistic research. As a result, we suggest that Mesolithic storytelling might have been entangled with ritual practices and accompanied by performances that resemble traditional shadow theatre.


A diode irradiation with 10-MeV protons was performed to measure the silicon current related damage rate at a temperature of -50°C. This measurement was fundamental to predict the performance of the detectors which will be used in the X-ray spectrometers of the Simbol-X and BepiColombo space missions. These detectors consist of arrays of large area silicon drift chambers with integrated depleted p-channel field effect transistors. The leakage current increase due to radiation damage and its consequent energy resolution degradation can be critical for these missions, specially for BepiColombo. These effects cannot be predicted because, during the whole missions, the sensors will be kept at temperatures below -40°C, and the existing models are based on measurements on structures which underwent annealing at higher temperatures. An irradiation experiment was performed to measure the current related damage rate at - 50°C, and the obtained value was (11.1 ± 0.2) X 10-17 A/cm. This result implies that it will be possible to achieve the Simbol-X energy resolution, whereas some annealing strategies will be needed for the BepiColombo mission. The annealing behaviour at 60°C was studied as well and the results are in agreement with the already available measurements.


We discuss digital signal processing (DSP) techniques for self-homodyne detection (SHD), multi-core fiber (MCF) transmission links, and related technologies. We focus on exploiting the reduced phase noise of self-homodyne multi-core fiber (SH-MCF) systems to enable DSP resource savings and describe digital receiver architectures that mixes signal and local oscillator in the digital domain.


This paper uses forecasts from the European Central Bank's Survey of Professional Forecasters to investigate the relationship between inflation and inflation expectations in the euro area. We use theoretical structures based on the New Keynesian and Neoclassical Phillips curves to inform our empirical work and dynamic model averaging in order to ensure an econometric specification capturing potential changes. We use both regression-based and VAR-based methods. The paper confirms that there have been shifts in the Phillips curve and identifies three sub-periods in the EMU: an initial period of price stability, a few years where inflation was driven mainly by external shocks, and the financial crisis, where the New Keynesian Phillips curve outperforms alternative formulations. This finding underlines the importance of introducing informed judgment in forecasting models and is also important for the conduct of monetary policy, as the crisis entails changes in the effect of expectations on inflation and a resurgence of the "sacrifice ratio". JEL Classification: E31, C53, C11


A 56-year-old woman presented with bright-red blood from the rectum. Esophagogastroduodenoscopy revealed mild gastritis. Colonoscopy demonstrated diverticulosis without active bleeding, and in vitro tagged red blood cell scintigraphy was unremarkable. There was no further evidence of bleeding and the patient was discharged home. The patient returned with recurrent bright-red blood from the rectum. Although delayed scintigraphic images seldom demonstrate the site of bleeding, delayed images at 12 hours demonstrated active bleeding near the hepatic flexure in this patient. This was confirmed with selective mesenteric angiography, and was treated with coil embolization of the tertiary branches of the right middle colic artery.


This chapter highlights the challenges that confront HBCUs in enhancement of student success and reduction of the achievement gap among Black students. There is also a focus on institution-centric factors related to administrative structure, leadership, governance, accountability and transparency, management of external relationships with stakeholders, internal culture and politics, among others. HBCU leaderships and stakeholders must implement fundamental changes to remain relevant and survive.


In this paper Availability Modeling and Behavioral Analysis of a single unit system with Preventive Maintenance and Degradation after Complete Failure using Regenerative Point Graphical Technique (RPGT) is discussed. Initially the unit is working at full capacity which may have two type of failures, one is direct and second one is through partial failure mode. There is a single server (repairman) who inspects and repairs the unit as and when need arise. On partial failure (before complete failure) server repairs the unit which is perfect, but the unit and on complete failure the unit cannot be restored to its original capacity. If the server reports that unit is not repairable then it is replaced by a new one. Fuzzy concept is used to determine failure/working state of a unit. Taking failure rates exponential, repair rates general and taking into consideration various probabilities, a transition diagram of the system is developed to determine Primary circuits, Secondary circuits & Tertiary circuits and Base state. Problem is formulated and solved using RPGT. Repair and Failure are statistically independent. Expressions for systems parameters i.e. mean time to system failure, availability, and number of server visits and busy period of the server are evaluated to study the behavior of the system for steady state. Particular cases are taken to study the effect of failure and repair rates on mean time to system failure, availability, and expected number of server visits and busy period of the server. Profit optimization is also discussed. System behavior is discussed with the help of graphs and tables.


There is ample evidence to suggest that space flight leads to immune system dysregulation. This may be a result of microgravity, confinement, physiological stress, radiation, environment or other mission-associated factors. The clinical risk from prolonged immune dysregulation during space flight are not yet determined, but may include increased incidence of infection, allergy, hypersensitivity, hematological malignancy or altered wound healing. Each of the clinical events resulting from immune dysfunction has the potential to impact mission critical objectives during exploration-class missions. To date, precious little in-flight immune data has been generated to assess this phenomenon. The majority of recent flight immune studies have been post-flight assessments, which may not accurately reflect the in-flight condition. There are no procedures currently in place to monitor immune function or its effect on crew health. The objective of this Supplemental Medical Objective (SMO) is to develop and validate an immune monitoring strategy consistent with operational flight requirements and constraints. This SMO will assess the clinical risks resulting from the adverse effects of space flight on the human immune system and will validate a flight-compatible immune monitoring strategy. Characterization of the clinical risk and the development of a monitoring strategy are necessary prerequisite activities prior to validating countermeasures. This study will determine, to the best level allowed by current technology, the in-flight status of crewmembers immune system. Pre-flight, in-flight and post-flight assessments of immune status, immune function, viral reactivation and physiological stress will be performed. The in-flight samples will allow a distinction between legitimate in-flight alterations and the physiological stresses of landing and readaptation which are believed to alter landing day assessments. The overall status of the immune system during flight (activation, deficiency, dysregulation) and the response of the immune system to specific latent virus reactivation (known to occur during space flight) will be thoroughly assessed. Following completion of the SMO the data will be evaluated to determine the optimal set of assays for routine monitoring of crewmember immune system function, should the clinical risk warrant such monitoring.


12 Ecological models help us understand how ecosystems function, predict responses to 13 global change, and identify future research needs. However, widespread use of models is 14 limited by the technical challenges of model-data synthesis and information management. 15 To address these challenges, we present a ecoinformatic workflow, the Predictive 16 Ecosystem Analyzer (PEcAn), that facilitates model analysis. Herein we describe the 17 PEcAn modules that synthesize plant trait data to estimate model parameters, propagate 18 parameter uncertainties through to model output, and evaluate the contribution of each 19 parameter to model uncertainty. We illustrate a comprehensive approach to the 20 estimation of parameter values, starting with a statement of prior knowledge that is 21 refined by species level data using Bayesian meta-analysis; this is the first use of a 22 rigorous meta-analysis to inform the parameters of a mechanistic ecosystem model. 23 Parameter uncertainty is propagated using ensemble methods to estimate model 24 uncertainty. Variance decomposition allows us to quantify the contribution of each 25 parameter to model uncertainty; this information can be used to prioritize subsequent 26 data collection. By streamlining the use of models and focusing efforts to identify and 27 constrain the dominant sources of uncertainty in model output, the approach used by 28 PEcAn can speed scientific progress. 29 We demonstrate PEcAn's ability to incorporate data to reduce uncertainty in 30 productivity of a perennial grass monoculture (Panicum virgatum L.) modeled by the 31 Ecosystem Demography model. Prior estimates were specified for fifteen model 32 parameters, and species-level data were available for seven of these. Meta-analysis of 33 species-level data substantially reduced the contribution of three parameters (specific leaf 34 area [SLA], maximum carboxylation rate, and stomatal slope) to overall model 35 uncertainty. By contrast, root turnover rate, root respiration rate, and leaf width had 36


Mobile edugames were popular and has grown rapidly due to their ease of access, affordability, and interactivity. There have been numerous arithmetic related mobile edugames developed and available online. However, there are not so many mathematics mobile edugames existed which emphasize the basic concepts in accordance with Indonesia available curriculum and optimalize specific learning methods that suitable for targeted learner have been developed, particularly in basic division and multiplication materials. Through this study, the design of mathematics mobile edugame about basic division and multiplication with repetitive addition and subtraction concept will be discussed using TPACK framework that generates design recommendation and its application in mathematics mobile edugame with discovery-based learning model as an outcome. It uses specific TPACK plot from PCK to TPACK. The result shows in optimization used of technology in mathematics mobile edugame design user cognitive psychology development, gameplay and applied learning method are the most important aspect that then generates an adventure-puzzle mathematics mobile edugame which utilizes storytelling as final result.


Material and methods: This study was conducted from April 2001 to December 2002. 100 patients were selected on the basis of symptomatology proforma, consisting six most common symptoms of dry eye such as dryness, grittiness, burning, redness, crusting and sticking of eyelashes. Those patients suffering from any two of these six symptoms were screened and included in the study group. This group was then subjected to three diagnostic tests such as Schirmer's test, Rose Bengal staining of the ocular surfaces and tear film breakup time. The sensitivity and specificity of these tests was determined for the diagnosis of dry eye.


This study provides comparisons of inequalities in mortality between the United States, Canada and France using the most recent available data. The period between 2010 and 2018 saw increases in mortality and in inequality in mortality for most age and gender groups in the United States. The main exceptions were children under 5 and adults over 65. In contrast, Canada saw a further flattening of mortality gradients in most groups, as well as further declines in overall mortality. The sole exception was Canadian women over 80 years old, who saw small increases in mortality rates. France saw continuing improvements in mortality rates in all groups. Both Canada and France have distributions of mortality that are much more equal than those in the United


As found in many reports and literatures, the dispersion and exfoliation of montmorillinite (MMT) clays are so difficult mostly due to the incompatibility disperse with hydrophilic clay from its tactoid form.The main aim in the present work relies on expansion of the interlayers clay to see what will happened to the mechanical properties. X-ray diffraction (XRD) patterns represent significant improvement in acid treatment relative to direct or other methods. The greatest mechanical property response is a result of directly injecting acid atoms and nanoclay into the polymer treatment during extrusion. It is observed that for concentrations as high as 4 wt%, XRD peaks are eliminated, suggesting a high degree of protecting to prevent exfoliation. In the present work, we have demonstrated a series of experiments to synthesize nano MMT by a sol – gel method, taking advantages of the less porosity. The dispersion of the nanoclay- montmorillinite (MMT) particles is studied with X-ray diffraction (XRD) technique. An increased d-spacing value of the clay particles in the nano composites is observed with acid treatment.


In recent years, robotic forceps are widely explored in the field of Robotics using various types of mechanisms. In this paper, we propose compact 4DOF robotic forceps for neurosurgery based on compliant mechanism. A notable feature of proposed robotic forceps is that the springs are largely deformed to transmit and transform the motion, therefore the manipulator's structure can be simple, thus can be miniaturized. We performed a series of Finite Element Analysis and showed that the proposed robotic forceps have sufficient working area and rigidity.


Dielectric measurement cells have been developed to determine the response of liquid suspensions of microorganisms. The dielectric response of some food related microorganisms have been investigated and the effectiveness of thermal, compressive, pulsed electric field and UV pasteurisation treatments assessed.


A convenient route for the synthesis of adenosine uses hypoxanthine, which is obtained easily and low prices, and phosphorus oxychloride as starting materials was proposed. The route involved three steps as chlorination, condensation and aminolysis, respectively. The reaction condition is mild and the overall yield is higher than other conventional chemical synthesis methods. Firstly, 6-chloropurine was obtained from hypoxanthine and phosphorus oxychloride by chlorination with 90.0% yield. Then, adenosine was produced from 6-chloropurine and tetraacetyl-ribofuranose without separation by condensation and ammonolysis with 75.0% and 66.7% yields, respectively. The total yield of three steps is 45%, the optimum reaction temperature of condensation and ammonolysis are 135 °C and 100 °C, respectiveely. The structures of the compounds were confirmed by TLC, IR, NMR and MS analysis.


The Reverend Rowland Hill, MA, was a well-liked 18th-century British preacher who became one of the greatest vaccination advocates of his time.1 Born on August 23, 1744, into a wealthy family in the English countryside, Hill enjoyed a privileged upbringing and attended Cambridge University. There Hill met his destiny through a chance encounter with George Whitefield, a traveling preacher and founder of Methodism. Inspired by Whitefield, Hill left academia after earning an MA and was ordained as a deacon in the Church of England.2 Assigned to a small-town ministry, Hill grew restless and set off, as did Whitefield, on preaching tours in England, Wales, Scotland, and Ireland. In time, Hill became one of the most popular ministers in the British Isles, regularly drawing crowds of thousands to dynamic open-air sermons.3 (Am J Public Health. Published online ahead of print March 21, 2019: e4-e5. doi:10.2105/AJPH.2019.305012).


There are two ways of drawing out a raw tape ; one (C method) is to draw up a raw tape perpendi cularly out of the inside of cut-materia ls, and to twist thus already twisted tape in its same direction, and the second (D method) is to draw out a raw tape tangentially from the outer surface of cut-materials, and to twist a flat tape which is not previously twisted at all. In testing strength, elongation and evenness of yarns produced by the above two methods, it is made clear that in case of a thin raw paper of Japanese paper yarn or paper yarn, there is no difference between the two differently produced yarns, but in case of a thick raw paper the yarn produced in D method has bigger breaking elongation, though there is no difference in breaking strength between the two differently produced yarns, if they were not given moisture.In C method the number of twist of tape when drawn up from the inside of cut-materials is different from that when drawn up from the the outer surface. Therefore in case that unevenness of twist number has serious effects on property of yarn, this C method can not be adopted. If unevenness of the twist number does not matter, any method of drawing a tape out of cut-materials can be adopted according to each twisting efficiency.


ARTICLE DETAILS ABSTRACT History: Accepted 25 April 2021 Available Online June 2021 This study investigates the impact of Exchange Rate (Rupees Vs US $) and oil prices (Pak. Petroleum) and on the inflation rate in Pakistan by applying the Co-Integration technique to the monthly data for all the three series ranging from January 2004 to January 2019. Unit root testing results provide strong statistical evidence for each of the series to be non-stationary at the level and stationary at first difference. Cointegration testing results confirm the existence of Cointegration among the selected time series. Moreover, the empirical results of the regression of inflation on the exchange rate and oil price also lead to conclude that both the series have a strong statistical significant impact on inflation in Pakistan.


A series of 16 patients with hemimyelocele is described. In this condition the spinal cord is split into two halves, only one of which bears the myelocele plaque. The child shows marked asymmetry of innervation of the lower limbs and where one limb is fully innervated there is a normally functioning lower urinary tract. All patients have been found to have a scoliosis, usually associated with structural abnormality of the spine. The pathological anatomy of the defect is discussed and possible mechanisms accounting for its occurrence are considered.


The article is devoted to the assessment of information competence of specialists in physical culture and sport. The levels of information competence of the person engaged into sports activities and physical culture are identified and characterized, the reasons for the lack of this competence are analyzed.


Normal, healthy human volunteers and patients with proved history of non-melanoma skin cancer have been tested for their capacity to develop contact hypersensitivity to dinitrochlorobenzene (DNCB) following exposure of buttock skin to acute, low-dose ultraviolet B (UVB) radiation. Using a radiation protocol that achieves virtually complete depletion of normal-appearing Langerhans cells from irradiated skin, it was learned that approximately 60% of healthy volunteers developed vigorous contact hypersensitivity (CH) when 2000 micrograms DNCB was painted on the irradiated site. These individuals were designated UVB-resistant, and were distinguished from other individuals, designated UVB-susceptible, who failed to develop contact hypersensitivity following an identical treatment protocol. It was then discovered that virtually all (92%) skin cancer patients exposed to UVB and DNCB failed to develop CH, i.e., were UVB-susceptible. In subsequent experiments, epicutaneous application of 2000 micrograms DNCB to unirradiated skin of UVB-susceptible individuals revealed a further distinction between normal persons and skin cancer patients. Approximately 45% of the latter (and none of the former) remained unresponsive (failed to develop contact hypersensitivity following this second attempt at sensitization), implying that they had been rendered immunologically tolerant. These tolerant individuals responded normally to the unrelated hapten, diphencyprone. We conclude that human beings resemble inbred strains of laboratory mice in that some individuals are UVB-susceptible, whereas others are UVB-resistant. Because the incidence of UVB-susceptibility was significantly higher in skin cancer patients, and as specific unresponsiveness could be demonstrated only in these patients, we propose that UVB-susceptibility, as we define it in this hapten system, may be a risk factor for the development of skin cancer.


In order to explore and design an energy-saving and environmental kang and improve indoor thermal environment and air quality in rural residence of northern cold area,carried out an investigation in Fangshengou Village of Nong'an County,Changchun city,Jilin Province.The result shows that local residents renovated the structure of kang,according to house pattern with new life style.On the basis of fully investigation of the new type of firewall-kang,the field and experimental test has been carried out in recent two years.The relationships among the working principle,characters and house pattern were analyzed.The conclusion shows that to some extent,firewall-kang can meet the need of the space heating winter,and accord with the requirement of new socialist countryside construction on comfort,health,environmental protection and economy.


Most ancient thinkers believed that passions corrupted rational thinking, and that reason should control passions; Jewish apologists, however, often chided Gentiles for being ruled by passion, and sometimes offered Jewish law as a way to achieve genuine mastery over passion. Using language familiar to his contemporaries, Paul argues that human passions have corrupted reason's ability to control them, and even right knowledge of God's law cannot deliver one from this enslavement. For Paul, however, Christ by the Spirit liberates from bondage to passion, enabling a relationship with and life pleasing to God.


OBJECTIVE
To evaluate the trend of mupirocin resistance in MRSA, isolated at the Clinical Microbiology Laboratory of a tertiary care hospital.

METHODS
A total of 200 MRSA strains recovered over a 2 year period from various body sites were tested using the 5 and 200 microg discs of mupirocin to detect its resistance.

RESULTS
High level and low level mupirocin resistance were detected in zero and 1% of MRSA strains, respectively. Resistance to other non beta lactam antibiotics was also high. No MRSA strains were found to be resistant to vancomycin and tegicycline.

CONCLUSION
Mupirocin resistance was found to be very low among local clinical isolates of MRSA. Its judicious use to decolonize nasal carriers should be promoted among hospitalized patients to avoid further transmission and infections due to prevalent endemic MRSA strains in any health care setting. Concomitantly, regular surveillance and effective infection control initiatives are desirable to reduce the incidence of health care associated infections due to MRSA and also of mupirocin resistance.


The exact value of the accretion rate in novae is very important to the theory of thermonuclear runaways and nova statistics. Estimates of the typical accretion rates in nova and novalike objects are 10 g/s (1.6 10~ M 0 / y r ) . Patterson (1984) estimated that if the above high accretion rate prevails the expected number of novae according to Bath and Shaviv (1976) exceeds the observed number. Prialnik, Livio, Shaviv and Kovetz (1982) have shown that no thermonuclear runaway can be obtained if the accretion ra te is as high as few 1 0 9 MQ/YI. Actually, the very strong thermonuclear runaways (TNRs) are obtained only for very low accretion rates namely, 1 0 1 0 to l O _ 1 1 M 0 / y r . A way out from this inconsistency was suggested by Shara, Livio, Moffat and Orio (1986) in the form of the hibernation model. In this model the high accretion rate is found only shortly before and soon after the nuclear runaway and the nova spends most of the time in a state of very low accretion rate so low that most novae are not observed at all. The high accretion rate, according to this theory, is a precursor to the runaway. The hibernation model is very attractive in spite of a meager observational proof so far and theoretical justifications. Yet, it is one of the most promising ideas in this field. The hibernation scenario claims that the accretion rate is a function of time. It is high just prior to the runaway and it continues to be high for some time just after the runaway. It then declines to very low values. From the point of the model for the thermonuclear runaway the problem is how the star reacts to a temporary high accretion rate that comes after a long period of low accretion ra te (Shaviv and Starrfield, 1987). Thus, even if the accretion rate is low during most of the time the phase of high accretion can still affect the outcome of the thermonuclear runaway. The crucial question from the hibernation and TNR point of view is how much mass is accreted with a very low accretion rate and how much mass is accreted during the episode of high accretion. If most of the mass is accreted at high accretion rate hibernation does not help to resolve the problems the theory of TNR has with the high accretion phase. It is therefore important to find the accurate accretion rate in nova and novalike objects. The purpose of this paper is to discuss the accretion rates in novalike objects. There are several observational results for novalike objects that allow us today to evaluate quite accurately the accretion rates from the continuum energy distribution of the accretion disc.


ABSTRACT Feedback from school leaders often is of low quality and not always effective. Because school leaders spend only limited time on instructional leadership activities, an intervention was developed to assist them in efficiently providing high-quality feedback to teachers. The effectiveness of the intervention was evaluated within a quasi-experimental study. N = 11 school leaders were trained in conducting classroom observations and providing feedback. School leaders observed teachers of the intervention group (N = 26) and provided feedback with regard to 14 teaching characteristics. N = 27 teachers served as a control group. It is examined whether the intervention leads to improvements in teaching quality perceived by students. Multilevel regression analyses were conducted. For three of the 14 teaching characteristics, intervention group students (N = 518) rated changes in teaching quality significantly better than control group students (N = 551). The results provide first evidence for the effectiveness of the intervention.


Objective To study the effect of stress stimulation in different intensity on bone-tendon repair process after acute rotator cuff injury in rabbits treated by bone rivets under arthroscopy.Methods According to whether performed postoperative function exercises,and the intensity of activity,30 adult New Zealand white rabbits were randomly divided into 3 groups: high-intensity experimental group(range of motion of shoulder joint was-60° to 60°),low-intensity experimental group(range of motion of shoulder joint was-15° to 15°) and control group(free activity permitted).Models of rotator cuff injury in rabbits were established,and bone rivets were used to repair the injury under arthroscopy.Joint functional exercises were performed 1 week after the surgery,MRI examination of shoulder joint were undergone simultaneously.Animals were sacrificed at 2,3,4 week after the surgery by intravenous injection of air respectively,and the stiffness and ultimate tensile strength of specimens taken from supraspinatus tendon-bone interface were observed in each group.Results Gross observation showed no obvious differences among 3 groups.In low-intensity experimental group,MRI results showed homogeneous signals in muscle tendon,while no obvious high signal intensity in articular cavity;In high-intensity experimental group and control group,heterogeneous signals in muscle tendon and high signal intensity in articular cavity were found in MRI images.At 2,3,and 4 week after the surgery,stiffness and maximum tensile strength in low-intensity group were significantly higher than those in control group and high-intensity group(P 0.05).Conclusion During the early repair process for acute rotator cuff injury treated by bone rivets under arthroscopy,low-intensity stimulation can improve biomechanical strength of bone-tendon interface,and therefore can get better effects compared with high-intensity stimulation.


The 3D ray tracing method requires a detailed description of the environment and antenna characteristics. Thus, it allows us to consider all the paths between receivers and transmitters for a fixed number of electromagnetic interactions. However, the computational complexity of this method is directly connected to the number of scatterers and the electromagnetic environment interactions. Thus we proposed an optimization method allowing reducing the computation time of a railway tunnel simulation. It consists in modifying the modeling environment, by eliminating non-significant faces. The aim of our method is, in this case, to provide estimated results close to those obtained with a complete environment modeling, but in fewer computation time.


Portrait of Balinese dancer, Sampih, master of kebyar seated dance, who toured the United States in 1952.
Title from item.
Van Vechten number: XVII JJ 11.
Formerly identified as Sampih in Kehyar.
Also available on microfilm.
Gift; Carl Van Vechten Estate; 1966.
Forms part of: Portrait photographs of celebrities, a LOT which in turn forms part of the Carl Van Vechten photograph collection (Library of Congress).


Massage is an activity of rubbing or massaging certain parts of the human body which aims to improve blood circulation and provide stimulation to relax injured muscles. In massage there are various kinds including beauty massage, health massage, sports massage. In this activity, the massage carried out by students of the PGRI Banyuwangi University is a health massage by means of reflection, massage is carried out on the legs so that it can stimulate nerves and can increase body immunity. It is hoped that with activities, especially the community around the PGRI Banyuwangi University campus, they can get health massage. The method of implementing this activity is 1) the activity preparation stage, 2) the implementation phase includes training on sports and massage activities, 3) the evaluation stage, which is making a final report. The results of the massage activities were quite a lot, the responses from the participants were quite good and they felt comfortable after the massage, the activity process was smooth and orderly.


As business competition globalizes, understanding user experience from various cultures plays a crucial role in design process. However, because most user research methods were developed in Western area, one may question if the expected result can be obtained when applying them to totally dif-


Safer, less expensive, and higher4quality health care can be achieved using clinical decision support (CDS), although the use of CDS often leads to disappointing results. Various problems and limitations can be pointed being the most frequently referred by the physicians the inadequate implementation of the clinical workflow. Electronic Health Records (EHR) and Patient Health Record Systems (PHRS) can play an important role in CDS mitigating those limitations and enabling the effective use of the archived information in the support of the clinical practice and generating the right knowledge to make decisions. The availability of such knowledge is crucial either, for the hospitals and for the government institutions. This brings new requirements for the EHR and PHRS conception and for the use of the information out of the boundaries of the hospitals and health centers. Interoperation and open models constitute the greater challenges that EHR enfaces in the very next future. This paper presents a survey on the design, development and implementation of PHRS in terms of organizational, regional, national and worldwide initiatives. Finally is presented the EHR implementation in the Hospital Geral de Santo Antonio, EPE, one of the major hospitals in the North Region of Portugal.


Title: Environmental Correlates of Efficiency and Safety in Emergency Departments Funds: Academy of Architecture for Health Foundation (AAHF) Research Grant and Herman Miller Grant Period: January 2010 to October 2012 Collaborators: Herman Miller, Synurgy Healthcare Solutions Location: Four emergency departments in large US hospitals Findings: 16 domains of physical design decisions influence safety, efficiency, or both in the ED: 1.entrance and patient waiting, 2.traffic management, 3.sub-waiting or internal waiting areas, 4.triage, 5.exam/treatment area configuration, 6.exam/treatment area centralization versus decentralization, 7.exam/treatment room standardization, 8.adequate space, 9.nurse work space, 10.physician work space, 11.adjacencies and access, 12.equipment room, 13.psych room, 14.staff de-stressing room, 15.hallway width, and 16.results waiting area.


We carried out optical pump-terahertz (THz) probe measurements to investigate the charge carrier dynamics of diketopyrrolopyrrole-linked tetrabenzoporphyrin (DPP-BP) thin films. In contrast to tetrabenzoporphyrin, DPP-BP exhibits broad and intense absorption, ranging from the visible and near infrared region. After the photoexcitation at 400 nm, we observed an instantaneous appearance of transient THz signals which are due to formation of free charge carriers. Transient signals decay with the time constants of 0.3 ps and 4 ps, meaning that charge carrier recombination and/or trapping take place on this time scale. For DPP-BP thin films, we found that near-infrared photoexcitation produces mobile charge carriers efficiently even without significant excess excitation energy. This will help to improve the power conversion efficiency for DPP-BP based solar cells.


Measurements of various particle species over an extended momentum range provide a sensitive experimental tool for investigating particle production mechanisms in hadronic collisions. Comparison of the spectral shapes from different collision centralities measured with the STAR detector at RHIC allows one to study the interplay of soft and hard particle production for mesons and investigate various baryon-meson effects. Systematic studies of identified particle spectra for various colliding systems and different incident energies provide additional insights toward the interplay between fragmentation and non-fragmentation contributions to the particle production. In these proceedings we present a systematic study of transverse momentum spectra for charged pions, protons and antiprotons from Au+Au and Cu+Cu data at sqrt(s_NN)=200 and 62.4 GeV as a function of collision centrality. We compare those measurements with p+p and d+Au data, investigating the system effects on energy loss.


Abstract This review covers over 110 monomeric Pt(0) organometallics and 220 monomeric Pt(II) organometallics. The predominant geometry for Pt(0) is square planar, with some examples of two-, five-, and six-coordinated. The monomeric Pt(II) organometallics in the review covers only those with the chromophores PtC4, PtA3B and PtC2A2. The most common ligand, besides C donor ligands, which are of a wide variety, is PPh3. At least two types of isomerism occur in the platinum organometallics analysed in this review: cis-trans and distortion. Relations between Pt-ligand bond distances, bond angles and transeffect are discussed regarding steric and electronic influence.


Purpose: The purpose of this study was to identify a causal relationship among major satisfaction, career decision autonomy, and career search behavior of nursing college students in clinical practice experience. Methods: Data were collected using a self-reported questionnaires from 197 nursing students in S city from December 1 to 23, 2016. These were then analyzed by descriptive statistics, ANOVA, t-test, Pearson correlation coefficient, and multiple regression using SPSS/PC+ program. Results: The results suggest that major satisfaction was correlated with career decision autonomy; likewise, major satisfaction was correlated with career search behavior. The factors influencing career search behavior were grades and major satisfaction. Conclusion: It is necessary to develop a learning method considering interest and aptitude to increase the satisfaction of the major and to apply the various programs to understand the self and the work environment so as to determine how desirable the course will be.


This study aims to examine the influence of book tax differences toward
earning changes. Earnings change is calculated by subtracting the net income one
period ahead with current net income and then divided by the current net income.
Independent variables used in this study is temporary differences and permanent
differences which are proxy of book tax differences, while the dependent variable
is earnings change.
The population of this study is the manufacturing companies listed in
Indonesia Stock Exchange in 2008-2010. Sampling conducted with a random
sampling technique. Based random sampling method, the sample obtained a total
of 31 companies. The method of analysis that was used to test the independent
variables influence the dependent variable is the multiple regression.
The results showed that permanent differences has no significant affect
toward earnings change. Temporary differences has no significant affect toward
earnings change


The article is devoted to the problem of development of verbal (speech) creativity of children of preschool age. The relevance of this problem is justified in connection with the special role of speech and the creative activity of a child of preschool age in the development of all his mental processes. The purpose of the article is to determine the scientific phenomenon of verbal creativity as one of the most complex types of preschoolers' creative activity, analyze the main provisions of the Federal State Educational Standard for Preschool Education related to the development of an active creative personality of a child, and describe various approaches to the implementation of these provisions in variable preschool education programs. The theoretical aspects of the problem of development of verbal (speech) creativity of preschool children are summarized: the mechanisms of preschoolers' creative activity are indicated, the definition of this concept is corrected, the types of verbal (speech) creativity are identified, the stages of the formation of verbal (speech) creativity of children are indicated. The tasks of educational areas "Cognitive development", "Social and communicative development", "Speech development" and "Art and aesthetic development" in the Federal State Educational Standard of preschool education aimed at the development of the child's creative potential are analyzed. The author has identified the specific content of the work on the development of verbal (speech) creativity in comparing a number of modern educational programs of preschool education (Exemplary educational program of preschool education "Childhood", Educational proПЕДАГОГИЧЕСКОЕ ОБРАЗОВАНИЕ В РОССИИ. 2019. No 5 7 gram of preschool education "Development", Approximate educational program of preschool education "Origins", Approximate educational program preschool education "Inspiration"). The main methods and techniques for the development of verbal (speech) creativity in these educational programs are summarized. Analysis of educational programs will help preschool teachers of education to take into account the features of the program in its implementation in the educational process and to ensure the successful solution of the tasks of developing verbal (speech) creativity of children.


In this paper, we investigate the behavior of charm and bottom distribution functions at low x with respect to the parametrization of the gluon distribution function in the framework of the nonlinear Gribov–Levin–Ryskin–Mueller–Qiu, Zhu-Ruan-Shen (GLR-MQ-ZRS) evolution equation. Also, we solve the GLR-MQ-ZRS equation using the parametrization behavior of the gluon distribution function. The computed results are compared with the NNPDF3.0, CT14 and GRV92 collaborations.


The present invention relates to method and apparatus for mixed mode operation and a method of setting a power management mode of the multi-core processor, mixed mode operation method of the multi-core processor according to the present invention comprises: a power management mode of the processor having two or more nuclei of when set, the user input to the mixing step mode power management mode of the system; and the step of setting said mixed mode of power management mode of the system. The present invention provides a mixed mode between the multi-core mode having two or more nuclei and only a single-mode core of the core, the present invention has the following effects: the user can be selected according to the performance of a variety of ways to play multi-core processor to the best, and the ability to effectively manage power consumption.


In Nb-Si based alloys with a two-phase Nbss/ intermetallic Nb5Si3 structure, the Nb5Si3 provides high-temperature strength, while the Nb solid-solution phase, Nbss, contributes to room-temperature ductility and toughness. The results show that in Nb-15W-10Hf-xSi alloys (x= 0.5, 5 and 18, mole fraction, %), the volume fraction of the Nb5Si3 is 0 for the 0.5% Si sample, 15% for the 5% Si sample and the 50% for 18% Si sample. With increasing Si content, i.e., the Nb5Si3 fraction, the high-temperature strength is improved considerably, but room-temperature ductility and toughness are degraded. For the sample Nb-15W-10Hf-18Si with 50% Nb5Si3, the compressive strength at 1 500℃and the room-temperature fracture toughness are 500 MPa and 6.8 MPa·m1/2, respectively, those for the Nb5Si3 free sample, Nb-15W-10Hf-0.5Si, are 190 MPa and 13.6 MPa·m1/2.


In this paper, two methods are proposed which address the random sampling and compressed sensing recovery problems. The proposed random sampling recovery method is the Iterative Method with Adaptive Thresholding and Interpolation (IMATI). Simulation results indicate that the proposed method outperforms existing random sampling recovery methods such as Iterative Method with Adaptive Thresholding (IMAT). Moreover, the suggested method surpasses compressed sensing recovery methods such as Orthogonal Matching Pursuit (OMP) in terms of recovery performance. We propose a compressed sensing recovery method, named Iterative Method with Adaptive Thresholding for Compressed Sensing recovery (IMATCS). Unlike its counterpart, Iterative Hard Thresholding (IHT), the thresholding function of the proposed method is adaptive i.e. the threshold value changes with the iteration number, which enables IMATCS to reconstruct the sparse signal without having any knowledge of the sparsity number. The simulation results indicate that IMATCS outperforms IHT and OMP in both computational complexity and quality of the recovered signal.


Due to the increasing deployment of PV systems in snowy climates, there is significant interest in a method capable of estimating PV losses resulting from snow coverage that has been verified for a wide variety of system designs and locations. A scattering of independent snow coverage models have been developed over the last 15 years; however, there has been very little effort spent on verifying these models beyond the system design and location on which they were based. Moreover, none of the major PV modeling software products have incorporated any of these models into their workflow. In response to this deficiency, we have integrated the methodology of the snow model developed in the paper by Marion et al. [1] into the National Renewable Energy Laboratory's (NREL) System Advisor Model (SAM). In this work we describe how the snow model is implemented in SAM and discuss our demonstration of the model's effectiveness at reducing error in annual estimations for two PV arrays. Following this, we use this new functionality in conjunction with a long term historical dataset to estimate average snow losses across the United States for a typical PV system design. The open availability of the snow loss estimation capabilitymore » in SAM to the PV modeling community, coupled with our results of the nation-wide study, will better equip the industry to accurately estimate PV energy production in areas affected by snowfall.« less


The construction of the Tugu Dam spillway does not escape the problem of slope instability, especially the rock fall type landslide as a result of the rock slope cutting work at STA+80. The purpose of this study was to determine the characteristics of the rock discontinuity area and the solutions needed to address the potential hazards of rock fall on the slopes of spillway structure. In this study, a semi-quantitative method conducted based on the Rockfall Hazard Rating System (RHRS) which is carried out by identifying outcrops on rock slopes. Determination of the rock fall trajectory, was conducted by statistical methods on rock mass based on changes in velocity when rocks roll, slide, and bounce. Geologically, the research area belongs to the Mandalika Formation. Based on the RHRS weighting, the total score on the STA+80 slope is 399, which means that the slope needs to be repaired or given safely with a moderate level of urgency. The rock fall trajectory modeling at the measurement location X = 121,875 has a kinetic energy of 973.14 kJ andesite and 72.59 kJ of volcanic breccia, for high results of 0.43 meters of andesite reflection and 2.04 meters of volcanic breccia, and velocity results translational velocity obtained at 33.8 m/s andesite and 8.67 m/s volcanic breccia. The potential for rock fall requires a safety system with a type of retained flexible barriers with a height of 5 meters that can be applied to the toe of the slope.Keywords: rock fall, discontinuity, trajectory, protection system, Tugu Dam


Abstract Empirical studies show that many governments gear the provision of goods and services towards their ethnic peers. This article investigates governments' strategies to provide ethnic favors in Africa. Recent studies of ethnic favoritism find that presidents' ethnic peers and home regions enjoy advantages, yet cannot disentangle whether goods are provided to entire regions or co-ethnic individuals. This article argues that local ethnic demography determines whether governments provide non-excludable public goods or more narrowly targeted handouts. Where government co-ethnics are in the majority, public goods benefit all locals regardless of their ethnic identity. Outside of these strongholds, incumbents pursue discriminatory strategies and only their co-ethnics gain from favoritism. Using fine-grained geographic data on ethnic demographics, the study finds support for the argument's implications in the local incidence of infant mortality. These findings have important implications for theories of distributive politics and conflict in multi-ethnic societies.


With the continued investment from the country,the scientific and technological strength was increased at the same time,and the fundamental laboratory conditions in each university were improved greatly.But the reform of teaching contents of the organic chemistry experiment for undergraduate fell behind,which was not benefit for the knowledge updating and the ability promotion.These recommendations were on account of the teaching experiences to overcome some defects in the present experiment education.These recommendations were also based on the teaching requirements and cultivation objectives of the organic chemistry experiments.


To reduce engine raw emissions and to improve the fuel consumption new designed combustion bowl and improved fuel injection systems were adopted R engine very limited cost increase. And to meet Euro 6 emission regulation LNT(Lean NOx Trap) a kinds of NOx aftertreatment were adopted. This research shows the way to meet Euro 6 emission regulation and European CO2 regulation with minimized cost effect and simultaneously increase engine output power, fuel consumption.


ABSTRACT Background Information about how individual characteristics influence preferences about health states valuation are scare. The purpose of this study is to identify predictors of the EuroQol with five dimensions and 3 levels – EQ 5D-3L time-tradeoff valuation. Research design and methods We analyzed a dataset with a probabilistic sample of 5774 individuals. Two sets of independent variables for testing were defined: a set of forced variables composed of 10 dummy variables for EuroQol levels 2 and 3 of each health dimension and a set of demographic variables. Results The strongest predictors of health valuation were the self-reported health state and the 'belief in God,' with 0.11 utility units for each VAS unit and 0.11 utility units for 'yes' for the 'belief in God' parameter.Age had an impact of 0.0190 utility units for each 10-year interval. Having children had a small effect (0.0338 utility units for 'yes'), and the other characteristics studied had no significant impact. Conclusions People who believe in God (or the afterlife) and those of greater age seem to be less prone to forgoing life years to avoid health problems. In our sample, older individuals valued health state higher than younger individuals.


Consider K-hop cascaded directed relay networks with time-division duplex (TDD), where the source, the relays, and the destination form a directed chain, and each node only receives the transmissions from its upstream node in the chain. We quantitatively investigate the effect of TDD constraint, which obviously prohibits the use of some network states and reduces the whole transmission rate. Firstly we define a new S sequence based on the famous Fibonacci sequence, which is proven to exactly characterize the amount of all feasible network states. We further find Fibonacci number FK is equal to the amount of new feasible network states when hop K is added and activated from K - 1 hop networks. Recursive construction method to get all feasible states is also provided, along with some important properties. Then we formulate the scheduling problem into a linear program and find the maximum achievable rate with decode-and-forward relay strategy is r* = min {C1C2/C1+C2, C2C3/C2+C3,..., CK-1CK/CK-1+Ck}, where Ck is the capacity of hop k. An example network is uWto demonstrate the scheduling process.


Abstract : A case study of the Central Materiel Services department at Madigan Army Medical Center was conducted in three phases to establish inventory levels of equipment located throughout the clinical areas of the hospital, to determine stockage levels of the most commonly used surgical instrument sets, and to conduct a pilot study showing the efficacy of an inventory management system using the Basic Laparotomy set as a study group. The clinical inventory identified a total of 779 separate lines of equipment, for a total of 4,581 instruments, sets, or other equipment. Eighty instrument sets were identified which represented 80% of the demand for sets within the hospital, and stockage levels to meet a 97% and a 99% demand satisfaction rate were computed and compared to actual inventory. Results from the pilot study showed significant differences between actual usage rates of instruments and stocked levels, but the sample size was too small to make recommendations for instrument stockage levels within the Basic Laparotomy set.


The effect of site properties and forest drainage on the dominant height development of Scots pine (Pinus sylvestris L.) stands in peatland sites was studied using data from permanent sample plots ...