strong sense of commitment to the union movement. As an example oftheir roles in union activity, the author notes that in 1919 General Motors had 200,000 workers, of which 6,000 were skilled craftsmen, constituting only 3 percent of the total workforce. According to Professor Babson, their preeminent role in the 1939 ". . . strike was perhaps the clearest indication of how Anglo-Gaelic leaders and activists played a disproportionate part in the founding of Detroit's auto unions" (p, 238). Building the Union is a detailed study of the formation of the United Auto Workers. Professor Babson presents a wealth of information. To a large degree he answers two central questions posed in his introduction: what brought these Anglo-Gaelic immigrants to Detroit and why did they play such a prominent leadership role in the city's auto unions. Therefore, as a study in labor history, this work is first rate. A problem, however, does emerge from this work. The author's assertion is that these leaders represent a skilled trade subculture with ethnic overtones. It is this latter point that is problematical. He includes immigrants from Great Britain, Ireland and Scotland in the Anglo-Gaelic category. There is no discussion of religious differences within the group. Immigrants from Ireland may bring with them cultural attributes somewhat different from immigrants from Great Britain and Scotland. It is assumed that labor activity is the major organizing focus in the formation of one's identity. While social class and ethnic identity are related, this relationship is not clearly delineated in this work. This critique aside, the work still has much to recommend it, and it should be of use to anyone interested in the role ofimmigrants in the formation of labor unions in the United States.


ABSTRACT Genetic gains of cultivated peanut (Arachis hypogaea L.) have increased harvest index and disease tolerance, resulting in improved yield potential and broad-range adaptability of peanut cultivars to United States (U.S.) peanut production regions. Although this strategy has been successful, future yield increases may require peanut cultivars specifically adapted to environmental and management systems of a particular production region. Irrigation is one major management factor that varies across U.S. production regions and influences yield stability. Therefore, peanut germplasm selection for developing specifically adapted cultivars depends on knowledge of genotypic (G) pod yield responses to irrigation (M) across contrasting environmental (E) conditions (G × E × M interaction). The objectives of this 2-year study were to characterize germplasm by: (i) examining genotypic pod yield response to irrigation at locations in Florida and Texas; and (ii) estimating the genotypic pod yield performance and stability using genotype plus genotype-by-environment interaction (GGE) biplots. At the Florida location, genotypes New Mexico Valencia C (NMVC), COC 041, and Chico responded positively to increasing water application, whereas FloRun™ '107ʹ, C76 16, and FlavorRunner 458 responded negatively. Genotypes C76 16, ICGS 76, Chico, and ICGV 86015 had pod yields greater than the population mean. The genotype ICGS 76 had both high pod yields and stability. Pod yields of Chico were greater at the southwest locations, whereas ICGV 86015 had greater pod yields at the southeast locations. These results demonstrate a range in adaptability of distinct peanut genotypes that can be used in breeding programs for developing improved cultivars. Abbreviations: G × E: genotype-by-environment interaction; G × E × M: genotype-by-environment-by-management interaction; G × M: genotype-by-management interaction; NMVC: New Mexico Valencia C; TWRPET: total water received as a percentage of ETo


The Newark Basin (NB) is a Mesozoic aged half graben that filled upward with nonmarine: (1) fluvial deltaic Stockton Formation, (2) deep lake LF, and (3) shallow lake playa – PF, now comprising the 3 major aquifers. Only the LF and PF aquifer matrix are enriched in arsenic and have natural aqueous arsenic issues. These formations strike ~ NE and dip ~ 12 degrees NW and the LF and PF are bedding confined, multi-layered, leaky aquifer systems. Much work to evaluate the sources and mobilization mechanisms of arsenic in the LF and PF aquifers has been conducted (Serfes, 2005; Zhu and others 2008; Serfes and others, 2010). Recent concerns about the significance of As mobilization from non-imported backfill to be used in a linear trench excavation transecting the LF and PF have been evaluated. Column leach testing of LF and PF rock particles used EPA Method 1627 (USEPA, 2011; Serfes, 2016). These test results not only provided information addressing the key concern(s), but also indirectly about what the major zones of As mobilization in these aquifers are. The EPA-1627 methodology and an improved biogeochemical model of As mobilization in the NB follows.


This report has identified a number of challenges associated with SEE governance in Myanmar, including revenue retention rules, management of Other Account balances, transparency, and budgeting and oversight. Furthermore, we have detected a number of specific risks to natural resource SEE profitability, specifically at MOGE and MGE. Here we provide recommendations on areas for reform and discuss what policy changes Myanmar officials could consider to address these risks and challenges. We also suggest a draft timeline on implementation of reforms.


As a way of overcoming general feeling of isolation and consequent high student evasion in Virtual Learning Environments (VLE), this article presents results of an experience with the i-collaboration model that promotes the collaboration between users in VLE. I-Collaboration is based in the virtual companion agents' (VLC) usage as collaboration monitors. The VLC are integrated with VLE collaborative tools and knows each student profile (MBTI) and behavior in the VLE. Based on these information, the VLC provides to the students a distinct perception and experience in the environment (human-centered design). Each student has the particular motivation to keep learning and collaborating, based on their own needs.


Optimization models have been developed, in which the levels of uncertainty and probability measures were used as optimization criteria. These models were used at the stage of preliminary design of technical objects in conditions of mixed uncertainty, when non-deterministic parameters were set using both statistical and expert information.


The influence of the surface preparation of AISI 316L stainless steel by mechanical grinding, polishing and following passivation was examined by immersion corrosion tests in solution simulating body fluids. Decreasing of the surface roughness by finer preparation resulted in decrease of corrosion rates of AISI 316L stainless steel. Passivation of specimens resulted in decreasing of the corrosion rates and in decreasing of the corrosion process speed independently on the roughness of specimens before passivations. Lowest corrosion rates were observed in the case of polished and passivated specimens. However no significant difference in corrosion rates between polished and ground specimens with following passivation was observed.


Stresses caused by thermal expansion coefficients mismatch of anodically bonded glass and silicon samples are studied. An analytical model to determine graphically the optimum bonding temperature is presented. It is essentially a model for thin-film stress but uses integration of the linear coefficient of thermal expansion difference between the bonding temperature and the working temperature. Recommendations for choosing the bonding temperature of silicon to two brands of glass (Corning 7740 and LK5) are made. Keywords: anodic bonding, field assisted bonding, thermal expansion, stress.


A concise and stereoselective synthesis of the highly oxygenated D-ring of the kinamycin family of antitumor antibiotics was achieved from commercially available 3-methyl-2-cyclohexen-1-one. The key steps included a regioselective isomerization of a cis-epoxy alcohol, a regioselective reductive ring opening of a benzylidene ketal, and a stereoselective α-hydroxy-directed ketone reduction. The Ullmann coupling between a bromonaphthaldehyde AB-ring fragment and an α-iodocyclohexenone, which is a versatile D-ring precursor, effected the construction of the functionalized ABD-ring system that may provide access to kinamycin F and its structural analogues.


Abstract In the given manuscript, the fractional mathematical model for the current pandemic of COVID-19 is investigated. The model is composed of four agents of susceptible infectious quarantined and recovered cases respectively. The fractional operator of Atangana-Baleanu-Caputo is applied to the considered model for the fractional dynamics. The basic reproduction number is computed for the stability analysis. The techniques of existence and uniqueness of the solution are established with the help of fixed point theory. The concept of stability is also derived using the Ulam-Hyers stability technique. With the help of the fractional order numerical method of Adams-Bashforth, we find the approximate solution of the said model. The obtained scheme is simulated on different fractional orders along with the comparison of integer orders. Varying the numerical values for the contact rate different simulations are performed to check the effect of it on the dynamics of COVID-19.


Treatment of (3S)-3-methylpiperazine-2,5-dione 6a with LHDMS followed by alkylation of the corresponding enolate with methyl iodide affords (3S,6S)-3,6-dimethyl derivative 7 in 98% de. The same reaction sequence carried out on (3R)-derivative 6b leads to a 93:7 diastereomeric mixture of (3R,6R)-8a and (3R,6S)-8b. Cleavage of the heterocyclic ring of 7 and 8a with 57% HI leads to (S)- and (R)-alanine, respectively. The configuration at C-3 (of 6a and 6b) and at C-6 (of 7 and 8a) can be assigned on the basis of 1 H NMR spectroscopy and conformational analysis performed by MMPMI


Background: Patient satisfaction has been identified as a critical success factor in the sustained long term success of practices in the health care industry. The Victoria University Osteopathy Clinic (VUOC) is a clinic, which provides a competitively priced, high quality service yet suffers currently from low patient numbers.
Conclusion: Extrapolation of conclusions from this study is difficult in view of the small sample size. This study indicates that current patients are mostly satisfied with the Victoria University Osteopathic Clinic, and suggests that any deficiencies in patient numbers may be due to limitations within the study.
This minor thesis was written by a post-graduate student as part of the requirements of the Master of Health Science (Osteopathy) program.


A water drain valve base of water tank of toilet comprises a lower connecting base connected with an outlet at the toilet water tank bottom, an up-down through outlet formed on the middle part of the lower connecting base, a connecting surface formed on the top surface of the lower connecting base, a water stopping convex ring formed on the inner part of the connecting surface and an upper connecting base connected with the outer part of the connecting surface. The top of the water stopping convex ring forms a water stopping surface. A water flowing wall is arranged on the outer part of the connecting surface, and the height of the water flowing wall is bigger than the height of the water stopping convex ring. The structure characteristic of the base is that the outlet can be furthest full of the water flowing through the outlet, thus the drainage speed increases, which can flush toilet out with smaller displacement.


The European Agency for the Evaluation of Medicinal Products (EMEA) was established in July 1993 to unify regulatory practices and improve market access within the European Union (EU). In February 1995, the EMEA implemented the centralized procedure for drug approval within the EU. The current study explores the history, goals, and implementation of the centralized procedure. We examine the time to obtain product marketing authorization for products that have gone through the process relative to the goals set for the program at its inception, and we compare approval times for a group of products that have been approved by both the EMEA and the United States Food and Drug Administration (FDA). Our data indicate that the goals established by the EMEA for the timeliness of application review have generally been met. Moreover, mean approval times for products approved by both the EMEA and the FDA were similar.


Highlight This work investigated the relationship between cell-wall properties in diverse maize lines that contribute to the differences in enzymatic hydrolysis yields for both untreated and mild NaOH-pre-treated biomass.


Generally, aggregation of the amyloid-s peptide is considered the cause of neuronal death in Alzheimer disease. The heterogenous As peptide occurs in various lengths in vivo: As40 and As42 are the predominant forms while both shorter and longer peptides exist. As40 and shorter isoforms are less aggregation-prone and hence considered less dangerous than As42 and longer isoforms, which are more aggregation-prone. Up to now research mainly focussed on the predominant As peptides and their individual characterization. This work emphasizes on the behavior of various isoforms in mixtures, as to mimick the in vivo situation. The results indicate that subtle differences in the ratio of As40 to As42 can induces strong differences in aggregation behavior and toxicity. This observation is not limited to these isoforms: a small fraction of the shorter As38 or the longer As43 affects the aggregation behavior of the predominant As isoforms. Additionally these minor peptides can enhance the toxic effects of As40 on neurons while damping that of As42. This is crucial for the development of new therapeutics as current strategies aim to decrease the production of As42 while increasing As38 levels at the same time. The strategy is based on the assumption that the presence of less aggregating As38 is less hazardous than that of As42. The results presented here however suggest that the situation is more nuanced. A detailed understanding of the agggregation behavior of less predominant As isoforms, in isolation but certainly in mixtures, will lead to better insight in the mechanisms leading to Alzheimer disease and as such contribute to improved therapeutic approaches.


This work studies the statistical limits of uniform convergence for offline policy evaluation (OPE) problems with model-based methods (for episodic MDP) and provides a unified framework towards optimal learning for several well-motivated offline tasks. We establish an ⌦(HS/dm✏) lower bound (over model-based family) for the global uniform OPE and our main result establishes an upper bound of Õ(H/dm✏) for the local uniform convergence. The highlight in achieving the optimal rate Õ(H/dm✏) is our design of singleton absorbing MDP, which is a new sharp analysis tool that works with the model-based approach. We generalize such a model-based framework to the new settings: offline task-agnostic and the offline reward-free with optimal complexity Õ(H2 log(K)/dm✏) (K is the number of tasks) and Õ(HS/dm✏) respectively. These results provide a unified solution for simultaneously solving different offline RL problems.


A methodology commonly used to calculate losses in shareholder actions against companies for failing to announce information relevant to the share price is based on price movements shortly after the ultimate announcement. This approach will lead to an overestimate of the loss if the market overreacts to the information. It can also lead to a wide range of estimates of loss. A better measure of the loss would be the loss in the intrinsic value of the company attributable to the new information. These arguments are illustrated by the recent case of Downer EDI.


The coalescence behavior of immiscible blends was determined by annealing the melt without shear. The kinetics and the mechanism of coalescence were observed for blends of thermoplastic polyurethane (TPU) and polyolefins. Two different types of measurements were used to observe coalescence in quiescent melt at the processing temperature. On the one hand, the blend granules were annealed in bulk. The resulting particle sizes were determined by light microscopy and by SEM on particles separated from the blend. On the other hand, thin samples were annealed on a hot stage. Coalescence was observed in situ by light microscopy or static laser light scattering. It was found that the higher viscosity and elasticity ratios between polyethylene and TPU lead to a more pronounced coarsening of the morphology of 80/20 blends than in TPU/polypropylene. It has been shown that the process of reshaping coalescence is one mechanism of coalescence that occurs in quiescent melt. Another mechanism that was directly observed is a domino effect where one coalescence process causes the next one.


Fifty outpatients suffering from rheumatoid disorders were treated with proglumetacin. Efficacy was classified as "good" or "very good" in 80% of cases. Besides this considerable efficacy, a tolerance classified as "good" or "very good" was observed in 86% of patients.


The investigation of the atomic and molecular structure of therapeutic or toxic compounds is important because it helps to understand their mechanism of action. Nitroaromatics are reactional intermediate compounds in chemical synthesis well known for their toxicity. In order to have a best insight of their structures and then to undertake a study of their possible toxic activities, we report here the singlecrystal X-ray determination of two nitrobenzene derivatives compounds:2-Morpholin-4-yl-5-nitro-benzaldehyde and 5-Nitro-2piperidino-benzaldehyde From the X-rays diffraction, the structure of both compounds has successfully been solved. The parameters of agreement R obtained are satisfying (4.50% and 5.30%). The analysis and interpretation of the geometrical characteristics relating to bond distances compared to standard values indicate that carbon-oxygen bonds: [d(C10-O4) = 1.420(2)Å and d(C9-O4) = 1.422(2) Å] are characteristic of simple bond between carbon sp3 and oxygen sp2 [C(sp3)-O(sp2)]. On the other hand, the distance d(C7-O3) = 1.194(1)Å is slightly shorter than the standard value (1.210Å) indicates a double bond between carbon sp2 and oxygen sp1 [C(sp2) = O(sp1)]. Bonds distances nitrogen-oxygen: [d(O1N1)=1.214(1)Å and d(O2-N1) =1.207(1)Å] indicate characteristic values of nitrogen-oxygen bonds in the nitro group (NO2). This assumption is confirmed by carbonnitrogen bond distance: d(C1-N1)=1.457(1)Å which corresponds to simple bond between an aromatic carbon and nitrogen [Car-NO2]. For aromatic ring, bond angles present no particularity. Indeed, bond angles values are nearly equal to 120° which represents average value observed in aromatic ring. The geometry and stacking in the crystals have been explained and that is essential to understand their behavior in synthesis. We retain that, the substituents on a molecule influence the bond lengths and bond angles in the geometrical structure. Also the stability in these molecules is governed by hydrogen bonds.


Copper, lead, cadmium and mercury concentrations were recorded in water and tissues of Oreochromis niloticus from Egyptian fish farms in 2007 -2009. Histopathological alterations in fish tissues were also studied. Bioconcentration factors of copper, lead, mercury and cadmium in liver and muscle tissue were (3.93 & 3.87), (8.10 & 7.60), (0.79 & 50.0) & (38.25 & 30.25), respectively. Mercury was the most bioaccumulated and biomagnified metal in the muscles, while Cu was the least. The concentration of cadmium, lead and copper were highest in liver and lowest in kidney tissue, while mercury (Hg) concentrations were highest in muscles, lowest in kidney tissue. Several histopathological changes were noted in muscles, liver, gills, kidney and intestine tissue attributable to heavy metals exposure. (Nature and Science. 2010;8(4):1 47-156). (ISSN: 1545-0740).


This paper analyses and presents the new scientific models and methods for the expert evaluation of quality of learning objects (LOs) paying special attention to LOs reusability level. Currently all existing approaches in the area are quite subjective and depend only on the experience of the decision-makers. The authors analyse several scientific methods and principles to minimise the subjectivity level in the expert evaluation of LOs quality. They are: (a) the principles of multi-criteria decision analysis for identification of quality criteria, (b) technological quality criteria classification principle, (c) fuzzy group decision making theory to obtain evaluation measures, (d) normalisation of the weights of criteria, and (e) scalarisation method for LOs quality optimisation. The authors demonstrate that the complex application of these approaches could significantly improve the quality of the expert evaluation of LOs and noticeably reduce the level of the expert evaluation subjectivity. The paper also presents the example of practical application of these approaches for evaluation of LOs for Mathematics subject. The main stakeholders in the educational sector are the educational institutions (schools, universities, etc.), educational authorities (such as ministries of education, regional and other agencies, etc.) and policy makers, and providers of learning content (e.g., publishers). Since educational institutions are interested to DOI: 10.4018/ijopcd.2011100105 International Journal of Online Pedagogy and Course Design, 1(4), 62-76, October-December 2011 63 Copyright © 2011, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited. use the quality LOs, they need some kind of proper approaches, models and methods how to choose the quality LOs in the market or to find free-of-charge LOs of high quality. The publishers are interested to propose such LOs to the institutions, and the policy makers are interested to know these approaches in order to formulate the education policy (e.g., while implementing the public tenders on provision the educational sector with LOs). All the education sector stakeholders need to know for sure what LOs are quality ones or what are not. Therefore, this problem is of very high practical relevance for the educational sector that needs clear and easy to use approaches to evaluate the quality of LOs, both proprietary and free ones. These quality evaluation models and methods have to fit all the stakeholders' needs. Therefore, the problem of evaluation of the quality of LOs is high on the agenda of the international research. Currently a number of LOs available through search engines and repositories is rapidly increasing. The provision of LOs ensures better access to quality LOs and supports enhanced learning outcomes. According to Haughey and Muirhead (2005), the purpose of LOs is to increase the effectiveness of learning by making LOs more readily available, also by reducing the cost and effort to produce quality LOs, and by allowing LOs to be more easily shared. One of the main criteria for achieving the high level of LOs effectiveness and efficiency is LOs reusability (Kurilovas, 2009c). According to McCormick et al. (2004), the need for reusability of LOs has at least three elements, namely: 1. Interoperability – it means that LO is interoperable and can be used in different platforms. 2. Flexibility in terms of pedagogic situations – it means that LO can fit into a variety of pedagogic situations. 3. Modifiability to suit a particular teacher's or student's needs – it means that LO can be made more appropriate to a pedagogic situation by modifying it to suit a particular teacher's or student's needs. The evaluation of LOs is a comparatively new concern because the quantity of LOs has grown and the development of their repositories has come about to allow for greater ease in finding and using LOs for blended learning (Kurilovas, 2009a). According to Haughey and Muirhead (2005), the growth in the number of LOs, the multiplicity of authors, their increasing diversity of design and their availability to educators has generated interest in how to evaluate them and which evaluation criteria to use to make judgments about their quality and usefulness. Teachers, students, and instructional designers can access large LO repositories and a number of even larger meta-collections such as European Schoolnet's (EUN – a network of 31 Ministries of Education in Europe) Learning Resource Exchange (LRE, 2010) which currently contains more than 130,000 LOs and assets from over 25 providers. As a pan-European service, the LRE particularly seeks to identify LOs that "travel well" (i.e., reusable) across national borders. These LOs can be used in a cultural and linguistic context different from the one in which they were created (eQNet, 2010). eQNet is a three-year (September 2009-2012) Comenius Multilateral Network funded under the European Commission's Lifelong Learning programme. The project is coordinated by European Schoolnet and involves 9 Ministries of Education (inc. Lithuania) or agencies nominated to act on their behalf. The primary aim is to improve the quality of learning content in LRE. eQNet will do this by establishing a network consisting of policy makers, researchers, and teachers that will develop and apply "travel well" quality criteria to LOs in the LRE. The vision driving the LRE is that a significant percentage of high quality content developed in different countries, in different languages and to meet the needs of different national curricula can be re-used at European level. eQNet will provide a forum for joint reflection and co-operation related to the exchange and re-use of LOs and allow the network members to: (1) better share information and 13 more pages are available in the full version of this document, which may be purchased using the "Add to Cart" button on the product's webpage: www.igi-global.com/article/application-multiple-criteriadecision-analysis/58663?camid=4v1 This title is available in InfoSci-Journals, InfoSci-Journal Disciplines Library Science, Information Studies, and Education, InfoSci-Select, InfoSci-Educational Leadership, Administration, and Technologies eJournal Collection, InfoSci-Networking, Mobile Applications, and Web Technologies eJournal Collection, InfoSci-Select, InfoSciSelect. Recommend this product to your librarian: www.igi-global.com/e-resources/libraryrecommendation/?id=2


Purpose: To assess the reliability and repeatability of periorbital biometric measurements using ImageJ software and to assess if the horizontal visible iris diameter (HVID) serves as a reliable scale for facial measurements. Methods: This study was a prospective, single-blind, comparative study. Two clinicians performed 12 periorbital measurements on 100 standardised face photographs. Each individual's HVID was determined by Orbscan IIz and used as a scale for measurements using ImageJ software. All measurements were repeated using the 'average' HVID of the study population as a measurement scale. Intraclass correlation coefficient (ICC) and Pearson product-moment coefficient were used as statistical tests to analyse the data. Results: The range of ICC for intra- and interobserver variability was 0.79–0.99 and 0.86–0.99, respectively. Test-retest reliability ranged from 0.66–1.0 to 0.77–0.98, respectively. When average HVID of the study population was used as scale, ICC ranged from 0.83 to 0.99, and the test-retest reliability ranged from 0.83 to 0.96 and the measurements correlated well with recordings done with individual Orbscan HVID measurements. Conclusion: Periorbital biometric measurements using ImageJ software are reproducible and repeatable. Average HVID of the population as measured by Orbscan is a reliable scale for facial measurements.


The painful business of bridging gaps, David Jasper the changinf of the host, translation and linguistic history, Stephen Prickett interpreting the language of St Paul, Dennis L. Stamps the Knox version, or the trials of a translator, translation or transgression?, Solange Dayras on retranslating John Henry Newman's "Callista", Michel Durand Judith and Holofernes, changing Biblical images in the history of art, Elizabeth Philpot from Roublev to Gunn, a Trinitarian approach, Christiane d'Haussy "La Meme Voix, Toujours", Yves Bonnefoy and translation, David Jasper the myth of translatability, translation as interpretation, Bernard Zelechow.


The use of ZnO for the functionalization of textile substrates is growing rapidly, since it can provide unique multifunctional properties, such as photocatalytic self-cleaning, antimicrobial activity, UV protection, flame retardancy, thermal insulation and moisture management, hydrophobicity, and electrical conductivity. This paper aims to review the recent progress in the fabrication of ZnO-functionalized textiles, with an emphasis on understanding the specificity and mechanisms of ZnO action that impart individual properties to the textile fibers. The most common synthesis and application processes of ZnO to textile substrates are summarized. The influence of ZnO concentration, particle size and shape on ZnO functionality is presented. The importance of doping and coupling procedures to enhance ZnO performance is highlighted. The need to use binding and seeding agents to increase the durability of ZnO coatings is expressed. In addition to functional properties, the cytotoxicity of ZnO coatings is also discussed. Future directions in the use of ZnO for textile functionalization are identified as well.


This diploma paper discusses the strategies used by pupils while solving tasks consisting of mathematical problems. The theoretical part of the paper introduces the basic terms concerning problem tasks as well as the most prevalent classifications of individual tasks. Included in this part is also a number of models and ways of problem solving, and some strategies to improve it further.
The empiric part of the paper features the results of the research questions. These were used to establish which solving strategies are most frequently used among the pupils and the pupils' effectiveness while using them; how effectively they use graphic illustrations while solving mathematical problems; whether pupils are able to use their experience of usefulness of graphical illustrations in similar situations; and finally, whether successfulness at Mathematics influences successfulness at problem solving as such.
The research data was gained by means of individual work with ten pupils from the 4th year of primary school who were given problem tasks to solve.
The research shows that various strategies were employed by pupils while solving problem tasks. The pupils generally help themselves by using graphical illustrations, however, the majority of them need to be reminded of this option. They can also use their newly gained experience in new situations as well.


The aim of this study is to analyze the importance and the contribution of the teaching of geography in the life and educational formation of the indigenous children, having as general objective: to analyze the importance of the geography discipline based on the Indigenous RCNEI for the education of the indigenous children. and specific: Understand how the teaching of geography acts as a driver of indigenous school development; identify how geography in indigenous school education acts as an instrument of resistance in the struggle for the preservation of their cultures; Discuss curricular geography as a contribution to indigenous geography. The work developed has as methodology the bibliographic and documentary nature, seeking the understanding established in the documents that guide the actions that should be experienced in the school environment when it comes to teaching geography.


Barley (Hordeum vulgare L.) is an important feed crop in eastern Canada. Although the grain is used mainly as a source of energy for monogastric animals, high grain protein concentration (GPC) is desirable. Commencing in 1987, a 4-yr field trial was conducted at the E.A. Lods Agronomy Research Centre of McGill University to evaluate the effects of N application on the GPC of spring barley. Cadette and Leger, which are adapted feed cultivars, and Argyle, an unadapted malting type, were grown with N rates of 0, 50, 100, 150, and 200 kg N ha −1 broadcast at seeding as NH 4 NO 3 . Two other treatments consisted of applying 100 kg N ha −1 at seeding and 50 kg N ha −1 as NH 4 NO 3 (broadcast) or urea (foliar solution) 6 to 10 d after awn emergence [...]


The authors reviews same basic information about stereochemistry in the sense to clarify the concepts of chirality, enantiomers, racemic mixtures and describe the development of a new single antidepressant, S-Citalopram. For those compounds in which the isomers differ in stereospecificity, this separation into a single enantiomer can result in significant changes in potency, tolerability, and efficacy.


The present invention relates to an automatic apparatus for synthetic peptide-based radiopharmaceutical, which radiopharmaceutical for diagnostic and / or therapeutic use, the apparatus comprising: - a structural support (100); - means for the stent structure (100) suitable the closed housing (200); - a first disposable master module (1); - a second disposable module (19), slidably coupled to the first master module (1); - a third disposable cuvette holder module ( 26) reversibly fixing said fastening means to the structural support (100) to allow it to convert the same with respect to the structure of the stent. The first (1), second (19) and the third module (26) is arranged to irreversibly engage to form a single disposable collector (300), the implementation of a full synthesis of the radiopharmaceutical in the interior of the collector process, whereby the collector (300) is removed a single set of elements from the contamination of a single apparatus as in the last cycle. The device (39) controlled by remote control and driving station, which includes an operator through a personal computer (PC) which interacts with the overall synthetic process, and for storing management involves the treatment provided to each patient obtained radioactive pharmaceutical synthesis device data (PE).


Now in its fifth edition, FUNDAMENTALS OF INFORMATION SYSTEMS continues to offer a concise overview of information systems fundamentals in a short, nine-chapter format. Students will be presented with the core IS principles, offered an overview of the IS discipline, and will learn the changing role of the IS professional. By achieving these goals, FUNDAMENTALS OF INFORMATION SYSTEMS will enable students, regardless of their major, to understand and use fundamental IS principles so that they can function more efficiently and effectively as workers, managers, decision makers, and organizational leaders. Each chapter has been completely updated with the latest topics and examples. Chapters have more than 50 new references; contain all new opening vignettes, Information Systems @ Work, and Ethical and Societal Issues special interest boxes; and contain examples of actual individuals and organizations using IS to their benefit.


Introduction. This article analyses the dissemination of tweets critical of one of the most controversial and widely publicised court rulings in Spanish history, which found a group of men guilty of abuse rather than the more serious crime of rape in 2018. Methodology. The study used a mixed method of quantitative and qualitative approaches, with a corpus for analysis of 73,904 tweets. Results. Of the total number of tweets obtained, 49,886 (67.5%) were retweets, while the other 32.5% were original messages with or without mentions of other users and replies to other tweets. Conclusions. The conclusions drawn are that Twitter has come to be recognised as the social network for expressing political outrage, and that the social protests on the network are associated with processes of militancy and feminist movement. Anonymity on these platforms tends to be viewed as an opportunity to freely express ideas and opinions that would otherwise be impossible to disseminate.


Diagnosing insulin resistance via an OGTT can be costly and impractical. However, this information can be useful in recommending proper diet for individuals interested in losing weight. This study examined the association between responses to a 36 question carbohydrate intolerance questionnaire (CIQ) and responses to an OGTT in 108 women (31.6±13 yr, 34.7±7% body fat, 25.3±4 kg/m2). Participants submitted to DEXA body composition, health marker determination, and underwent a serial sampled (0, 30, 60, 90, and 120 minutes) 75 g OGTT. We examined the relationship between CIQ questions and the 2hr OGTT sampling (G120) and glucose AUC (GAUC). Results revealed significant correlations (p<0.05) between G120 (112±25 mg/dl) and perceptions of being >25 lbs overweight (r=0.25), waist:hip ratio (r=0.28), and BIA body fat (r=0.22). Results also revealed significant correlations (p<0.05) with GAUC (264±46 mg/hr/dL) to being overweight throughout life (r=‐0.19), being overweight since youth (r=‐0.27), gaining weight after age 30 (r=0.20), eating 3 meals/d (r=‐0.19), and waist:hip ratio (r=0.33). These findings indicate that OGTT G120 and GAUC results correlate with simple CI questions and basic body comp/health measures that may help practitioners make more informed recommendations about appropriate diet interventions.


The problems of treatment of inflammatory complications that have arisen in the delayed period after dental implantation, whose appearance adversely affect the safety of implants, remain complicated. Preventing the development of pathology periimplantitis one of the most important points for retaining implants. The purpose of evaluation of the effectiveness of the complex of preventive measures of periodontal supportive therapy in patients with dental implants was conducted a prospective randomized comparative study. In periodontal treatment AUZ «Republican stomatologic polyclinic» the city of Ufa for 2013-2016 monitored 87 patients with concomitant generalized periodontitis mild in remission who received dental implants for two-step protocol 190 Mis implants (Israel), aged 34 to 53 years, 39,1% male, 60,9% of women. The follow-up period was 3 years. ПАРОДОНТОЛОГИЯ №2 (83) 2017 85 КЛИНИКА Professional oral hygiene in the control group (14 persons, 31 implant) included hardware method of ultrasonic removal of hard dental deposits (700 Piezon, EMS, tool P in the region of the teeth, PI in the field of implants) and mechanical method of removing plaque. The main group, depending on the volume of interventions was divided into 3 subgroups. In group 1A (22 patients, 35 implants) in addition to hardware removal of hard deposits held air-abrasive removal of the biofilm above and below the gum with Perio powder (glycine) (AirFlowMaster, EMS), in group 1B (21 patients, 36 implants) complex of hygiene and hardware removal of solid deposits and mechanical plaque was supplemented by injection of autologous platelet plasma (Plasmolifting). In group 1C (30 patients, 88 implants) were included and Pexxrio and Plasmolifting. Developed taking into account the pathogenetic mechanisms of development of inflammatory complications in the field of dental implants, a combined method of prevention of dental periimplantitis with application of methods of Perio-Flow and Plasmolifting showed high efficiency in comparison with the standard methods and applying these methods separately. The application of this design in the complex of supportive periodontal therapy in this group of patients may contribute to the prevention of inflammatory-destructive complications and to increase the service life of the prosthetics with support on dental implants.


The present work investigates the linear and mass attenuation coefficients for gamma rays practically and theoretically by using spectroscopy gamma ray (UCS-20) and program (XCOM)) for various types of common use granite, and compares them with the lead because of its high blocking ability for this type of radiation. This paper concluded through linear and mass attenuation coefficients measurements that these coefficients decrease with increasing incident photons energy. Measurements also showed that the linear attenuation coefficients appropriate linearly with density while mass attenuation coefficients do not get affected.


Since 2001, when the winner of the Nobel Prize for physiology and medicine found crucial moderators in cyclin-dependent kinase (CDK) and cyclin (Koepp et al., 2001; Duman-Scheel et al., 2002), the study of the cell cycle and associated moderators has become a hot area in tumor research. Factors associated with cell cycle control can be divided into three groups: cyclins, CDK, and cyclin-dependent kinase inhibitor (CDKI). CDK is found at the core of cell cycle control. Cyclins take positive actions towards CDK and CDKI takes negative actions; together, they form the cell cyclin controlling system. CDKI, as an "anti-oncogene" can arrest cell cycle progress and induce cells to enter apoptosis by arresting cells at checkpoints in the cell cycle (Eddy, 1996). CDKIs can be divided into two families: the inhibitors of CDK4 (INK4) family and the CDK-interacting protein kinase inhibition protein (CIP/KIP) family, also called the p16 and p21 families, respectively. The INK4 family includes p15, p16, p18, and p19; they are all the specific inhibitors of CDK4/CDK6. The CIP/KIP family includes


Some glucosinolate enzyme hydrolysis derived products were produced, chemically characterized and studied to investigate their inhibitory activity on seed germination. The glucosinolates epi-progoitrin, glucoerucin and glucoraphenin were isolated from ripe seeds of Crambe abyssinica Hochst. ex R.E. Fr., Eruca sativa Mill, and Raphanus sativus L., respectively. The effect of hydrolysis products on seed germination of three weeds, viz. Chenopodium album L., Portulaca oleracea L., Echinochloa crus-galli (L.) Beauv. and Lactuca sativa L., cv. 'Romana', as control, was evaluated under controlled conditions. The results of these assays showed a total inhibition of seed germination produced by the hydrolysis products of glucoerucin at a concentration of 10 mg ml -1 of native glucosinolate. The hydrolysis products of glucoraphenin showed similar activity. The only exception was E. crus-galli, which demonstrated germination values significantly higher than those of the other species. The hydrolysis products of epi-progoitrin, mainly 5-vinyloxazolidine-2-thione, gave a high percentage of abnormal seedlings even at a concentration of 1 mg ml -1 of native glucosinolate.


The change in benefits of high socioeconomic status to fertility in humans during the demographic transition from high to low fertility has interested both demographers and evolutionary biologists. Evolutionary analyses add to demographic analyses by considering also males and status-related differential in male mating success, but they have been limited to time cross-sections and have not linked this differential to differentials in other determinants of male fertility. We use life-history records of males (n = 3791) entering marriage market before (1810s–1880s) and during (1890s–1960s) the Finnish fertility transition to investigate associations between socioeconomic status and chance and timing of marriage, choice for spouse, and lifetime fertility. Low status invariantly brought a lower marriage chance throughout these 160 years, which partly explained why ever-married high-status men lost advantage at early marriage when the system of achieving a high status shifted from inheritance to self-effort. The loss, coupled with assortative mating by age, promoted disappearance of differential in wife's age at marriage and thus, disappearance of differential in fertility between ever-married high- and low-status men in the Finnish fertility transition. Consequently, among all men (married and unmarried), status-related differential in lifetime fertility—not selection coefficient—declined over the transition. This study is among the first to show the interrelated dynamics of status-related differentials in male mating and reproductive traits; by doing so, it contributes to an evolutionary understanding of change of status–fertility relationship in human fertility transition and confirms continuing phenotypic selection on male status/wealth in modern societies.


Steps 1. Shutting down the target controller on page 1 2. Opening the system on page 7 3. Removing the NVRAM battery on page 8 4. Removing the NVRAM DIMM on page 10 5. Installing the NVRAM DIMMs on page 13 6. Installing the NVRAM battery on page 13 7. Reinstalling the controller module and booting the system on page 13 8. Checking the status of the battery and running diagnostics on page 15 9. Completing the replacement process on page 17


The performance of a silane-penetrating water-repellent material applied to three concrete mix types was evaluated using alternative test procedures. One of the mix types was similar to standard reference concrete often used in laboratory testing. The other two mixes represented structural deck concrete and high-density overlay concrete, with correspondingly lower water-cement ratios and varying mix designs. Performance was evaluated with respect to depth of penetration, absorption, water vapor permeability, and chloride ingress. Test procedures and mix type were both found to affect the parameters used to evaluate the performance of the treated concretes. Results indicate the need to represent field conditions (such as mix design) to the extent possible in order to better predict field performance with laboratory tests.


A clinical survey of 500 Spanish patients has found that smokers needed more health treatment, consumed more prescription drugs and took more days off work than non-smokers.


As a result of recent advances in signal processing technology and standards for video compression systems there has been a dramatic increase in interest in commercial applications. This paper reviews the current broadcasting situation from a number of viewpoints relevant to the future development of the available technologies.

After a review of the context, which includes alternative new broadcasting technologies as well as alternative media capable of competing with satellite, digital technology is given a wide ranging assessment with particular attention paid to the direct broadcasting to the home by satellite application currently receiving considerable attention world-wide. The possible system architectures and subsystem design features are highlighted with the European Baseline Satellite Broadcasting specification developed by the European Digital Video Broadcasting Project gaining special attention. For completeness a brief review of the digital audio broadcasting system (DAB) is also given.

In addition to the applications for direct broadcasting, applications in the professional domain for distributing television signals from studios to terrestrial transmitters, satellite up-link sites or cable heads or for satellite news gathering (SNG) are examined. Features of existing commercially available hardware to support these services are described briefly.


The aim of this paper is to present a general description about the method called Extremum Seeking Control (ESC), and its applications in the nonlinear systems, which have an unknown dynamics. The system we are interested in is the photovoltaic system. This technique presents a solution on real time optimization control problems.


Incomplete instrument is a new and important subject in the field economic law. This paper analyses the legislative situation and defect about it in China. In addition, based on using the successful legislative experience of developed countries, the author puts forward some legislation proposals on incomplete instrument system.


The invention discloses an isolation device for maintaining an isolation disconnecting link. The isolation device comprises a first insulation baffle, a second insulation baffle, a first locking device and a second locking device, wherein the first insulation baffle is used for isolating a cross arm and the disconnecting link and for isolating the contact of the cross arm and the disconnecting link, the first insulation baffle is provided with a first china bottle clamp slot and a second china bottle clamp slot which are distributed parallelly, and the openings of the first china bottle clamp slot and the second china bottle clamp slot are in the same direction; the second insulation baffle is connected with the first insulation baffle, and is used for isolating the contact between disconnecting links, and the second insulation baffle is arranged between the first china bottle clamp slot and the second china bottle clamp slot; the first locking device is arranged at the opening of the first china bottle clamp slot and is used for closing and opening the opening of the first china bottle clamp slot; the second locking device is arranged at the opening of the second china bottle clamp slot and is used for closing and opening the opening of the second china bottle clamp slot. The isolation device is simple to operate, low in cost and is safe and reliable.


In this study, we demonstrated the use of plasma electrolysis as a low-energy, efficient method of producing biobased chemicals from cellulose. We used high-voltage alternative current electricity as the plasma source in polar aprotic solvents to achieve complete liquefaction of cellulose without the use of external heating. A levoglucosenone yield of 43% was obtained after 15 min of conversion in γ-valerolactone using a voltage of 6 kV and frequency of 6 kHz, and a 38% yield was obtained within 3 min in sulfolane using a voltage of 4 kV (or 40% after treating for 7 min with the voltage of 3.5 kV). Compared to conventional liquefaction in the same solvents, plasma electrolysis could produce much greater LGO yields using significantly less energy. In this study, the plasma electrolysis of cellulose in γ-valerolactone was able to increase the levoglucosenone yield by 154% while using only 28% of the energy consumed during conventional thermal-based conversion of cellulose in the same solvent for producing its maximum yield of 17%. When the same conversions were performed in sulfolane, a 28% higher levoglucosenone yield was produced while requiring only 3% of the energy consumed during the respective thermal-based conversion of cellulose to obtain its maximum yield of 31.2%. The study also revealed that the plasma electrolysis of cellulose proceeds through novel radical-based mechanisms involving in situ-generated hydrogen radicals, by which cellulose depolymerizes and dehydrates much more efficiently than it does during conventional liquefaction. During the plasma electrolysis process, cellulose conversion was significantly enhanced by synergistic effects between Joule heating and plasma chemistry.


Recessive dystrophic epidermolysis bullosa (RDEB) is a severe, complicated inherited blistering skin disease with few treatment options currently available. Recently, haematopoietic stem cell transplantation (HCT) has been used as an alternative therapy that can improve skin integrity, but it is not known if the preparative HCT regimen also contributes to the therapeutic response.


Efficient fences will not only help improve the performance of today's concurrent algorithms, but could also pave the way for the adoption of stronger memory models such as Sequential consistency (SC). However,the cost of fences in commodity processors remains prohibitively expensive. A hardware fence only requires that all memory accesses preceding a fence in the program order are performed before the fence and its following memory accesses are performed. But, it does not require that these operations are completed in that order. In this work we observe that a significant fraction of fence overhead is caused by stores that are waiting for data from memory. We propose the zFENCE architecture that exploits this observation for efficiently implementing a fence by introducing the capability to grant coherence permission for a store much earlier than servicing its data from memory. We show that zFENCE eliminates fence overhead in a majority of scenarios, and helps bridge the performance gap between SC and TSO runtime memory models for a low design cost.


ARTHROLOGY AND JOINT ENDOPROSTHETICS MATERIALS FOR JOINT ENDOPROSTHESES DESIGNS OF JOINT ENDOPROSTHESES SOME CLINICAL ASPECTS OF ENDOPROSTHETICS TRIBOLOGICAL ASPECTS OF ENDOPROSTHETICS SIMULATION OF CARTILAGE TISSUES SIMULATION OF BIOPOTENTIALS IN JOINTS EDVANCES IN JOINTS ENDOPROSTHETICS


ABSTRACT Patients with diabetes mellitus may have gastrointestinal complications of gastroparesis diabeticorum, bacterial overgrowth and/or diabetic diarrhea. Patients with diabetic diarrhea thought to be secondary to diabetic neuropathy usually have ten to 30 stools/day, with large volumes of more than 200 g/day, but weight loss is distinctly unusual. Gastroporesis diabeticorum may have weight loss associated with its gastric dilation and retention of food if vomiting is present. A woman with both gastroparesis diabeticorum, diabetic diarrhea, and, in addition, possible bacterial overgrowth who had a marked weight loss of 52 pounds without any vomiting is described. This patient, who had a normal fecal fat excretion and negative stools for bacteria, ova, and parasites, did respond to tetracycline each time her diarrhea reappeared after several diarrhea-free months in a 3-year follow-up. Metoclopramide did not help this patient and may have contributed to worsening her diarrhea. Thus, even if bacterial overgrowth cannot be documented by quantitative bacterial cultures of intestinal contents, a trial of antibiotics appears reasonable when other causes of diarrhea have been ruled out in diabetics. This treatment allowed the patient to regain weight she had lost.


Chronic Kidney Disease (CKD) is characterized by progressive loss of kidney function over time due to kidney damage or reduced glomerular filtration rate (GFR) <60 mL/min/173m 2 for >3 months. The increased levels of urea in patients with chronic kidney failure can cause pruritus known as uremic pruritus or chronic kidney disease associated pruritus (CKD-ap). The research method that will be used is PRISMA. These scoping reviews will use a systematic approach and selection process. Library sources were traced from the Proquest, PubMed, Scopus and Google Scholar databases. This scoping review examines the associated factors with pruritus in patients undergoing dialysis. Factors related to uremic pruritus, namely based on analysis through scoping reviews that have been carried out on 8 articles, it was found that the most widely used study design was cross-sectional, the most widely used type of dealisis is hemodialysis with the number of articles is 3 articles and the number of patients that is male 505 samples (60.4%) and women 331 samples (39.6%) with the Total is 836 samples. Factors associated with uremic pruritus are gender, age, dialysis dose, duration of dialysis, urea/urea, C-Reactive Protein (CRP), and parathyroid hormone (PTH).The conclusion is that the factor that most dominant factor


I. Materials And Methods Patient Population Our study includes 50 women of age varying between 28 to 55 years who were admitted. We included only the patients with technical success in transvaginal sonography and Hysteroscopy in this study. Finally 50 patients with pathological confirmation were included in this study. All 50 patients were first evaluated with transvaginal sonography followed by Hysteroscopy and traditional curettage with cervical biopsy performed after 2 days following transvaginal sonography[7MHz]The pathological findings are then correlated with ultrasound finding and diagnosis by hysteroscopy.


The present invention is to provide a composition for increasing feed intake and promoting growth and a method for preparing the same, wherein the composition is added to a feed, which is then fed to livestock having reduced appetite due to disease or stress, thereby effectively recovering or increasing the amount of feed intake, thus promoting the growth of livestock and improving productivity. To achieve the purpose, the composition is prepared by mixing 0.2-5.0 wt% of a Crataegus pinnatifida extract, 2.0- 20.0 wt% of a cyproheptadine dispersant, 1.0-5.0 wt% of liquid paraffin, 25.0-50.0 wt% of zeolite, and 25.0-71.8 wt% of a roasted chaff powder.


Best practices for ocular and cervical VEMP tests" (2015). Independent Studies and Capstones. Paper 701. Abstract: The VEMP is a relatively recent addition to the clinician's test battery. The following Capstone will provide protocol for the use of both VEMP tests as part of a complete vestibular diagnostic test battery.


Sugar Research Australia (SRA) has released three new sugarcane varieties that are aimed at delivering significant benefits to Australian cane growers and millers.


34 Introduction: Uterine artery (UtA) Doppler indices are one of the most commonly employed 35 screening tests for pre-eclampsia worldwide. Abnormal indices appear to result from increased 36 uterine vascular resistance, but anatomical complexity and lack of appropriate animal models 37 mean that little is known about the relative contribution of each of the components of the uterine 38 vasculature to the overall UtA Doppler waveform. Previous computational models suggested 39 that trophoblast-mediated spiral artery remodeling has a dominant effect on the UtA Doppler 40 waveform. However, these models did not incorporate the myometrial arterio-venous 41 anastomoses, which have significant potential to affect utero-placental haemodynamics. 42 Methods: We present a more anatomically complete computational model, explicitly 43 incorporating a structural description of each component of the uterine vasculature, and 44 crucially including myometrial arterio-venous anastomoses as parallel pathways for blood- 45 flow away from the placental bed. Wave transmission theory was applied to the network to 46 predict UtA waveforms. 47 Results: Our model shows that high UtA resistance indices, combined with notching, reflect 48 an abnormal remodelling of the entire uterine vasculature. Incomplete spiral artery remodelling 49 alone is unlikely to cause abnormal UtA Doppler waveforms as increased resistance in these 50 arteries can be 'buffered' by upstream anastomoses. Critically, our results indicate that the 51 radial arteries, may have a more important effect on utero-placental flow dynamics, and the 52 UtA Doppler waveform than previously thought. 53 Conclusions: This model suggests that to appropriately interpret UtA Doppler waveforms they 54 must be considered to be reflecting changes in the entire system, rather than just the spiral 55 arteries. 56 57 58 59 60 61 62 63


AbstractPermeable pavements are often developed as alternatives to traditional pavement (TP) systems for the mitigation of urban stormwater runoff impairment. The objective of this study was to eva...


This special issue of the ACM Transactions on Design Automation of Electronic Systems (TODAES) contains 9 papers that were presented at the SIGDA/DAC University Booth during the 43rd Design Automation Conference (DAC) in San Francisco. Since 1987, the SIGDA/DAC University Booth (UBooth) program has been providing an excellent opportunity to the academic community to demonstrate their design techniques and tools, large-scale hardware or software projects, and educational material. Many students and faculty have benefited from the UBooth program over the last few years. At the same time, this program has made the DAC event a more interesting and learning experience for many DAC attendees. To highlight some of the work that is showcased as part of the UBooth program, the SIGDA Advisory Board in consultation with the TODAES Editor-in-Chief, Professor Nikil Dutt, has decided to include the "best" of the UBooth presentations at the 2006 DAC as peer-reviewed articles in TODAES, hence, this special issue was born. As announced in the call for participation, the focus of the special issue is on the research work that is dedicated to developing prototype software systems and/or experimental hardware platforms that offer a significant innovation in tackling key Electronic Design Automation (EDA) problems. To ensure the quality of the contributions, we also required that they contain both practical aspects of the software tool or hardware platform development as well as new and substantive algorithmic and/or theoretical enhancements to the state-of-the-art. Preference was given to the manuscripts which had accompanying technical or design contest papers at the 43rd DAC. System-level modeling, simulation, and synthesis using electronic design automation (EDA) tools are key steps in designing communication and signal processing systems. This special issue includes four articles on the system-level EDA. In the first article entitled "Efficient Simulation of Critical Synchronous Dataflow Graphs", Hsu et al. present a novel simulation-oriented scheduler (SOS) that integrates several techniques for graph decomposition and synchronous dataflow (SDF) scheduling to provide joint minimization of time and memory requirements for simulating critical SDF graphs. The authors have implemented SOS in the Advanced Design System from Agilent Technologies and obtained large improvements in simulating large-scale wireless communication systems. Herrera and Villar in their article,"A Framework for Heterogeneous Specification and Design of Electronic Embedded Systems in SystemC", describe a methodology that enables heterogeneous specification of complex, electronic systems in SystemC, supporting the integration of components under


Objective:To investigate the relationship between apolipoprotein C3 gene-482TC polymorphism and metabolic syndrome. Method:The restriction fragment length polymorphism(RFLP) of-482TC was studied using polymerase chain reaction(PCR) in 60 control subjects and 60 subjects with metabolic syndrome(MS group) from Chinese Han nationality in Fujian province. Result:ApoC3 gene polymorphism frequencies distribution was obviously different between MS group and control group(P0.01).The frequencies of T,C alleles of-482TC polymorphism were 55.8%,39.2% and 44.2%,60.8% in MS group and control group,respectively.There were significant differences in allele frequencies between MS group and control group(P0.05). Conclusion:Allele of apolipoprotein C3-482T polymorphism is associated with MS.


We study the geodesic flow on the unit tangent bundle of a rank one manifold and we give conditions under which all classical definitions of pressure of a Hölder continuous potential coincide. We provide a large deviation statement, which allows one to neglect (periodic) orbits that lack sufficient hyperbolic behaviour. Our results involve conditions on the potential, which take into consideration its properties in the non-hyperbolic part of the manifold. We draw some conclusions for the construction of equilibrium states.


The reaction between hydrogen and pyrites under suitable conditions gives good yields of hydrogen sulphide; practically the whole of the labile sulphur of pyrites can be removed from the ore, leaving ferrous sulphide. Under the conditions described in this paper, the rate of formation of hydrogen sulphide from pyrites increases to a maximum and then falls off according to the exponential law. The optimum conditions for the reaction are: (a) temperature of reaction should be 625-650°, (b) space velocity of hydrogen should be 40-50 volumes hydrogen per volume of pyrites at kiln temperatures of 625-650°. Corrosion of plant materials is greatly diminished by using mild steel "servarized" by aluminium. Size of pyrites has little effect on reaction time if the lumps of ore are not greater than 1 1/2 in. More than 90% of the arsenic in pyrites is removed as arsenious sulphide, which passes over suspended in the exit gases.


Some problems,which are existed in design and construction of condenser vacuum measurement sampling,were introduced.Taking the vacuum measurement of 600 MW unit of Sichuan Guang'an Power Generation Corporation Limited as example,the feasibility of the multi-point converged sampling reformation scheme,the goal of which is to increase the measuring accuracy of the condenser vacuum,was demonstrated.After the scheme had been implemented,the measurement accuracy of the condenser vacuum was increased,which provides certain convenience for the unit operators to adjust the unit efficiency;and favorable effect was obtained.


We think of a myth as a fictional story, and Plato was the first to use the term "muthos" in that sense. But Plato also used "muthos" to describe the practice of making and telling myths, the oral transmission of all that a community keeps in its collective memory. In the first part of this text, Luc Brisson reconstructs Plato's multifaceted and not uncritical description of "muthos" in light of the latter's famous Atlantis story. The second part of the book contrasts this sense of myth, as Plato does, with another form of speech which he believed was far superior: the "logos" of philosophy. Brisson's work is part lexical, part philosophical, and part ethnological, and Gerard Naddaf's substantial introduction shows the originality and importance both of Brisson's method and of Plato's analysis in the context of contemporary debates over the origin and evolution of the oral tradition.


Summary The UV-C radiation has been used as alternative method to control postharvest diseases in fruit. The brown rot is a major disease that affects peaches since the beginning of development until senescence. This study evaluated the effect of UV-C in the induction of resistance to brown rot of peaches cv. Chimarrita on fruit with and without injuries. The variables evaluated were disease severity, the phenolic content and antioxidant capacity. The application of UV-C as a preventive and curative control don't protect the peach against pathogen infection in both fruits with and without injury. However, in one day delayed the appearance of lesions in the fruits not injured, which could be economically interesting for the production chain of peach. In assessing the content of total phenolics and antioxidant capacity found that fruit subjected to UV-C showed increases in these properties. These results indicate that physical tratament (UV-C) enchances the secondary metabolism, at least of phenolic compounds synthesys, but not enough to increases of rot resistence.


The countries that comprise the Atlantic Basin2 are facing major challenges regarding energy and transportation. There are many factors affecting the Atlantic Basin's future, such as mass migration from rural to urban areas and the resultant impact on transportation, water, food, and energy security; reconsideration of central station electric generation as the only reliable means of energy production; environmental impact of fossil fuels; accelerated adoption of renewable energy technologies; emergence of electric vehicles as a plausible alternative for multiple transportation modes; evolving expectations of consumers for greater control of their lives; and income disparity and its impact on the quality of life of low-to-moderate income people.


Assuming postures and taking over a 'corner', thus unleashing love and hatred, can be the most effective way to position a brand. Regarding the construction of brands, we continue moving in the traditional schemes: "I believe, although I do not necessarily do it". For better or for worse, Petro and Trump reminded us that the famous marketing mix starts with a good product that is dressed in a striking package, moves in the right channels and is understandable in his speech. To love or hate them, they are coherent products.


We analysed the expression of three drug transporter proteins [p‐glycoprotein (PGP), lung resistance‐related protein (LRP) and multidrug resistance‐associated protein (MRP1)] involved in anthracycline resistance that are frequently overexpressed in poor‐risk adult acute non‐lymphocytic leukaemia (ANLL), in 23 acute promyelocytic leukaemia (APL) patients at onset managed at a single institution. Cellular daunorubicin accumulation was also evaluated. At onset, no case had PGP or MRP1 expression that exceeded that of non‐multidrug‐resistant (MDR) cell lines. Only one case showed LRP overexpression. No peculiar MDR features distinguished the seven patients who relapsed from those who maintained complete remission. In the onset vs. first relapse, only one patient showed an increased (threefold) PGP expression at relapse. At second relapse, three out of four patients showed a PGP expression two‐ to threefold higher than baseline values. These results are consistent with the view that low PGP, LRP and MRP1 expression and the absence of defects in intracellular drug accumulation may account for the peculiarly high sensitivity of APLs to anthracycline. It does not support the screening of MDR markers in APL patients at onset as predicting factors of early relapse. The results suggest that no significant changes in PGP, LRP or MRP1 expression are likely to occur at first relapse. In contrast, PGP expression is likely to increase later in the patient history as a result of additional chemotherapy courses.


Improvements in the clinical outcomes of pancreatic cancer patients may be achieved if physicians could identify the disease earlier. Recent studies demonstrated the promise of a biomarker panel is a simple combination between CA19-9 and another marker called sTRA, so named because it detects the sialylated version of the glycan bound by the TRA-1-60 (tumor-related antigen) antibody. The sTRA glycan is structurally related to the CA19-9 antigen and is produced by a different subtype of cancer cells than make CA19-9. We hypothesized that, among patients with PDAC, different patients have plasma elevations in CA19-9 than have plasma elevations in sTRA, and that as a result, a panel comprising the two markers detects more cancers at high specificity (low false-positive rate) than either marker alone. To test this hypothesis, we analyzed the relationships and biomarker performance of CA19-9 and sTRA across seven different datasets, encompassing 729 patient samples collected from four different clinical centers. We tested whether unique elevation occurred for each marker in each dataset, and whether the combination of markers performed better than then individual markers for distinguishing PDAC from healthy subjects and from benign pancreatic disease. We observed complementary elevations of sTRA or CA19-9 in the PDAC patients in each dataset. A two-marker panel composed of CA19-9 and sTRA and a three-marker panel composed of CA19-9 and two versions of the sTRA immunoassay gave statistically significant improvements over CA19-9 across the datasets for distinguishing PDAC from non-PDAC samples (healthy, chronic pancreatitis, pancreatic cyst, and biliary stricture/stones). At 95% specificity, sensitivity was improved from 36-55% across datasets for CA19-9 to 61-67% across datasets for the three-marker panel. The lead panel further showed 95% specificity and 61% sensitivity using blinded calls on another validation set (N = 340). This analysis serves as broad support for an improved serological test for PDAC using the combination of CA19-9 and sTRA. In light of this level of validation, the lead panel could be considered the most promising panel from the currently available information. If further validated using clinical assays, it may be good enough for surveillance among patients with increased risk for PDAC, in combination with follow-up modalities to establish diagnosis. Citation Format: Ying Liu, Ben Staal, Daniel Barnett, Zonglin He, Chongfeng Gao, Mark Hurd, Pamela Bartlett, Aatur Singhi, J. Bradley Morrow, Gregory Cote, Anirban Maitra, Ying Huang, Randall Brand, Brian Haab. Blinded and meta-analysis validation of an improved serological test for PDAC using the combination of CA19-9 and the sTRA glycan [abstract]. In: Proceedings of the AACR Virtual Special Conference on Pancreatic Cancer; 2020 Sep 29-30. Philadelphia (PA): AACR; Cancer Res 2020;80(22 Suppl):Abstract nr PR-010.


The results of the theoretical analysis of dynamics of correlation determination between the contradirectional waves in ring lasers for low frequencies are given. This dynamics ensures a differential mode of an operation of the ring lasers as a sensor of the angle displacements. Presence of two modes of stabilization of a correlation is determined: a fast and a slow.


A rhymed prose "Crickets Fight" is written by Dashan Monk in the 19th year of Kangxi,Qing Dynasty.The article describes the whole process of seeking,catching,and raising crickets in different environments as well as the terrifyingly fighting to reflect the real society in Qing Dynasty.It also warns people to stay away from fighting and endangering,but to embrace the simple life in forests for fulfilling Buddhism ideals.


Prostaglandin E2 (PGE2) in the preoptic area (POA) mimics fever by stimulating thermogenesis in brown adipose tissue (BAT), skeletal muscle via shivering and the heart via tachycardia, as well as by reducing heat loss via skin vasoconstriction. PGE2‐evoked stimulations of BAT, shivering EMGs and heart rate (HR) are postulated to arise from disinhibition of thermogenesis‐promoting neurons in the dorsomedial hypothalamus (DMH), and possibly in the rostral raphe pallidus (rRPa), due to the EP3 receptor (EP3‐R)‐mediated inhibition of GABAergic, warm‐sensitive neurons in the POA that project to inhibit DMH (and possibly rRPa) neurons. We tested the hypothesis that neurons in the medial preoptic (MPO) provide the necessary excitatory drive to downstream, thermogenesis‐promoting neurons for febrile heat production. Bilateral muscimol injection in the MPO completely inhibited the shivering EMGs and reversed the increases in BAT temperature and HR following injection of PGE2 into the POA. We conclude that the MPO contains neurons whose activity is necessary to support thermogenesis during fever. The data are consistent with a model in which a population of MPO neurons provides a tonically‐active, excitatory (glutamatergic) input to DMH (and rRPa?) neurons that drives thermogenesis upon disinhibition of DMH neurons during EP3‐R activation in the POA and potentially during cold exposure. Support NIH grant NS40987.


The article examines the question of implementation of the right to inherit or, in other words, the excercise of the successoral option. With the opening of succession, every successor has the right to accept or to renounce the succession. This option can be exercised by way of concluding unilateral legal transactions, such as acceptance of succession and renunciation of succession. These two legal transactions are analysed in regard to the form of expression of will and the legal consequences they produce. As long as acceptance of succession may be express or tacit (deduced from some factual circumstances clearly attesting the will of an heir to inherit), renunciation of succession has to be express or result from the law which attaches legal consequences to the non-acceptance of succession, i.e. to silence on the part of an heir. The article also deals with the question relating to the time limits for excercing the successoral option. Under Lithuanian law, a successor has three months from the opening of the succession to deliberate and exercise his option. Author comes to a conclusion that this period could not be regarded as an extinctive time limit which extinguishes the subjective right of an heir to inherit. The question of revokation of unilateral legal transactions is analysed in the case of a renunciation of succession. While debate is taking place as to the possibility to revoke the renunciation of succession, the author of this article proposes to establish a rule allowing a successor, who has renounced, to retain the faculty of accepting succession if it has not been accepted by any other person or if the other heirs, who have accepted, do not object to such a revokation. In such a case the heir would take the succession in its actual condition at the time of revokation and without prejudice to the rights which third parties may have acquired to property of the succession. Author comes to a conclusion that the two concepts used in the text of the Civil Code of the Republic of Lithuania – "renunciation of succession" and "non-acceptance of succession" – are not identical concepts and do not entail the same legal effects. If a successor dies before exercising his option, his own heirs acquire the right to deliberate and exercise the option instead of the successor who died. In the case of renunciation, the trasmition of the right to inherit is not passed onto the heirs of the successor who has renounced and who himself died. The article takes a comparative approach, presenting some of the solutions accepted in the legal systems of France, Quebec, Germany and Russia.


Given uncertainty in the input model and parameters of a simulation study, the goal of the simulation study often becomes the estimation of a conditional expectation. The conditional expectation is expected performance conditional on the selected model and parameters. The distribution of this conditional expectation describes precisely, and concisely, the impact of input uncertainty on performance prediction. In this paper we estimate the density of a conditional expectation using ideas from the field of kernel density estimation. We present a result on asymptotically optimal rates of convergence and examine a number of numerical examples.


The angular–diameter distance D A of a galaxy cluster can be measuread by combining its X– ray emission with the cosmic microwave background fluctution due to the Sunyaev–Zeldovich effect. The application of this distance indicator usually assumes that the cluster is spherically symmetric, the gas is distributed according to the isothermal β–model, and the X–ray temperature is an unbiased measure of the electron temperature. We test these assumptions with galaxy clusters extracted from an extended set of cosmological N-body/hydrodynamical simulations of a ΛCDM concordance cosmology, which include the effect of radiative cooling, star formation and energy feedback from supernovae. We find that, due to the steep temperature gradients which are present in the central regions of simulated clusters, the assumption of isothermal gas leads to a significant underestimate of D A. This bias is efficiently corrected by using the polytropic version of the β–model to account for the presence of temperature gradients. In this case, once irregular clusters are removed, the correct value of D A is recovered with a ∼ 5 per cent accuracy on average, with a ∼ 20 per cent intrinsic scatter due to cluster asphericity. This result is valid when using either the electron temperature or a spectroscopic– like temperature. When using instead the emission–weighted definition for the temperature of the simulated clusters, D A is biased low by ∼ 20 per cent. We discuss the implications of our results for an accurate determination of the Hubble constant H 0 and of the density parameter Ω m. We find that H 0 can be potentially recovered with exquisite precision, while the resulting estimate of Ω m , which is unbiased, has typical errors ∆Ω m ≃ 0.05.


A review of digital sine-wave generator architectures suitable for implementation in gate array is given. The goal is implementation of the three-phase sine-wave reference generator in ROM-less gate array with less than 200 gates


In this article we define a fractional forward discrete operator. Then, for a family of linear non-autonomous fractional difference equations constructed by using this fractional discrete operator, we provide a practical formula of solutions. This family of problems covers several linear fractional difference equations that appear in the literature. Numerical examples are given to justify our theory.


Internal transport barrier (ITB) modes have been observed with intense, off-axis ICRF heating in Alcator C-Mod. This barrier mode is routinely produced in enhanced Dα H-mode, 4.5 T, 0.8 MA discharges (H cyclotron position is r/a∼0.5 to the high field side). From TRANSP analysis, the χeff is significantly reduced inside r/a∼0.4 where the density peaking is observed. With the barrier formation, the toroidal plasma rotation near the axis reversed from co-current (+50 km/sec) to counter current direction (−20 km/sec). In an effort to maintain the barrier, experiments utilizing a third antenna, operated at 70 MHz, allowed central ICRF heating of the ITB mode. Initial experiments with up to 1.2 MW confirmed the energy transport barrier and allowed significant increase in the ion temperatures. With the central heating, the ITB was sustained and the density and impurity peaking were arrested. Furthermore, the central rotation was observed to rotate in the co-current direction with the central heating. We have als...


We have studied the behavior of three photospheric lines (Fe I 537.9, C 1538.0 and Ti II 538.1 nm), which have been monitored on the Sun for more than twenty years, either as full-disk or as center-disk measurements (Gray & Livingston 1997; Livingston & Wallace 2003). The aim is to detect a possible photospheric variation with the cycle. We try to reconstruct the cyclic variations of full-disk line depths as due to active region (AR) modulation through a spectral synthesis with FAL semi-empirical models (Fontenla et al. 1999) weighted by AR coverage factors. The sensitivity of these lines to thermodynamic variations and to AR presence is analyzed. We show that the AR modulation alone cannot explain all the observational results, either in amplitude or in phase. The "residual", i.e. the difference between observed behavior of these three lines at full-disk and that predicted by models for the AR modulation, results in a signal that is correlated with the measured center-disk line variations, and should be free from magnetic effects. Both the full-disk and the center-disk data show several periodicities; furthermore there are two periodicities shared by the three lines, one close to the 11 yr magnetic cycle and the other of 2.8 yr.


This paper proposes and describes a cell-level forward error correction (FEC) scheme in the ATM Adaptation Layer (AAL) for ATM networks. An FEC scheme will benefit real-time needs of multimedia applications as well as reliable (error-free) data communications. ATM network performance degrades rapidly with increasing cell loss or the bit error rate. The achievable throughput for reliable services also deteriorates with increasing packet or frame size or with increasing number of receivers in a multicast operation. FEC-SSCS can improve end-to-end QoS in all these cases. 1 From October 1997, Georg Carle is with GMD Fokus, Kaiser-Augusta-Allee 31, 10589 Berlin, Germany


Soybean pests and diseases are quite abundant and have shown the resistance to chemical pesticides. Biopesticides are biological agents derived from plant metabolites and microorganisms. They are effective for controlling pests and diseases as well as suppress the resistance and resurgence. This research aimed to study the impact of biopesticide inundation on soybean pests and diseases. The study was conducted in Banyuwangi, East Java. Biopesticides applied were Trichoderma harzianum (Trichol 8), neem seed powder, entomopathogenic virus SlNPV (Virgra), entomopathogenic fungi Beauveria bassiana, and eugenol from clove oil. The results showed that biopesticide applied by inundation can suppress Sclerotium rolfsii, Phakopsora pachyrhizi, Xanthomonas axonopodis, and Spodoptera litura. The application of biopesticides by inundation is safer and can maintain the survival of natural enemies and can reduce yield losses. However, the application of chemical can kill natural enemies. Oxyopes sp., Coccinella sp., Sycanus sp., Andrallus sp., Rhynocoris sp., Paederus sp., Entomobrya sp., Aphidius sp., Binodoxys sp., Encarsia sp., Trichogramma sp., and Telenomus sp. which survived on field applied with biopesticides is quite abundant. Therefore, natural enemies have a great opportunity as biological agents for controlling soybean pests and diseases and as an alternative to replace the use of chemical.


A polymer of formula (VII): wherein m is about 0, 1 to about 0, 9; p is about 0, 9 to about 0, 1; n is about 50 to about 150; each R1 is independently (C2-C20); each R2 is independently hydrogen, or (C6-C10) alkyl (C1-C6); each R3 is independently hydrogen, (C1-C6), alkenyl (C2-C6), alkynyl (C2-C6), or (C6-C10) alkyl (C1-C6); and each R4 is independently (C2-C20).


A programme of integrated enteral nutrition treatment is proposed for severe cases of anorexia nervosa. Such treatment seems better to satisfy patients' requirements and is closer to normal physiological nutrition. Treatment techniques are described and the results discussed, while the advantages of this therapy over all other methods used until now are underlined.


USN networks can be classified into IP-based and non-IP-based. Each type may build its own management architecture based on a specific management protocol. For example, ZigBee networks are established without IP, but 6LoWPAN networks are based on IP, especially IPv6. There two different management schemes such as ZigBee network layer management and SNMP are applied each to them. A centralized network management requires a common identification scheme for all managed objects within its management domain possibly consisting of multiple sensor networks based on IP or non-IP. SNMP uses IP and OID (object identifier) for identification of managed objects. But ZigBee-like non-IP sensor networks don't use IP and OID for object identification. This situation means a network manager should handle two identification schemes for every managed object within these two example networks. So, a higher layer abstraction of USN network management has been developed based on ID for a single and common identification scheme for all managed objects within a management domain, which can realize a transparent network management for various types of sensor networks.


ABSTRACT This work presents experimental results of combustion characteristics of low volatile Indian coal. Coal of different average relative density (ARD) varying from 1.35 to 2.0 was generated by density fractionation of the coal. Coal samples were characterized by proximate analysis, Fourier-transform infrared spectroscopy (FTIR), ultimate analysis, and gross calorific value (GCV). Combustion experiments were conducted to identify the effects of ARD and functional groups on combustion characteristics. It was observed that with the rise in ARD of coal from 1.45 to 2.0, the ignition temperature increased from 357°C to 417°C. Highest coal combustion rate was observed for 1.525 ARD coal, due to the presence of all types of hydrocarbons, alcoholic, aldehyde, and trisubstituted alkene (except primary amines) as seen from FTIR analysis. Analyses of coal combustion rate and GCV indicate that 1.45 ARD coal has the highest GCV, heat release rate, and lowest ash generation rate, properties that are best suitable for thermal utilities.


Definition of Resume. Marketing Yourself. Types of Resumes. What Employees Want to See. Writing the Resume. Objectives. Target the Resume to Desired Position. Strategies to Customize the Resume Teach Position. Putting Your Resume On the Internet, Get the Interview and Get Hired! Step-by-Step Instruction on How to Find the Hidden Jobs in Targeted Companies. Use the Resume to Get the Interview and Ultimately the Job. Sample Cover Letters and Matching Resumes.


This article revisits one of the established hypotheses in the literature on European industrial relations. Focusing on the context in which wages are set via central coordination, the hypothesis explores why the wage-setting system often collapses and is replaced with sectoral or company-level bargaining. The answer revolves around the issue of wage costs, with the main claim being that the change (that is, de-coordination) occurs when employers are not satisfied with the performance of cost control. This article asserts that the hypothesis has only limited applicability. In particular, it holds only if central coordination remains a potential source of high wage costs. If the system turns to a reliable mechanism for wage moderation, which is true in the Eurozone countries, the hypothesis does not hold. Under this circumstance, employers will no longer consider de-coordination as a means of cost control. Instead, de-coordination can occur as a consequence of intra-union politics, as diverse union actors interact with each other in their response to the wage issue. The article will examine this new hypothesis of de-coordination in the context of three Eurozone countries in the 1990s and 2000s: Finland, Ireland, and Belgium.


Cooperative spectrum sensing with the crowdsourcing model has become an innovative and efficient technique for obtaining the spectrum state information (SSI) under the cognitive radio networks. Specifically, the secondary users sense the licensed spectrum then send the SSI back to the fusion center according to the crowdsourcing model. In practice, the users with malicious or erroneous behavior are always existing among those secondary users. Thus the accuracy of spectrum sensing would be influenced by those users. In this paper, a novel crowdsourcing algorithm for cooperative spectrum sensing is proposed to detect the malicious users and further improve the accuracy of spectrum sensing. The agreement ratio is introduced in the proposed scheme, which is an important information under the crowdsourcing framework. Simulation results show that the proposed algorithm possesses better performance than the existing approaches.


We study dark and bright solitons in confined Bose-Einstein condensates of ultracold gases with repulsive and attractive atom-atom interaction. First, we compute analytic properties of the solitons in absence of the trap. Then, we consider the problem of the collision of a bright soliton with a barrier. This is studied by solving numerically the 1D Gross-Pitaevskii equation in the presence of a harmonic oscillator potential and a Rosen-Morse barrier. We discuss in detail the conditions for having a transmission coefficient of T = 0.5. Then, we study the evolution of the energies during this process and the nature of the part transmitted.


A computational study is done to carry out ion implantation for isolation in gallium oxide based devices using SRIM‐2013 simulation tool. In this paper, deep acceptors for gallium oxide like Mg‐ and N‐based implantation results and damage physics are discussed. Displacement per atoms (DPA)‐based calculation is done to compare damage analysis for N and Mg ion implantation at 50 KeV beam energy. DPA calculations show that Mg generates more damages and vacancies to target gallium oxide with compared to N ion implantation. Furthermore, ion implantation doses are also calculated for isolation of 300 nm target depth of gallium oxide. Multiple energy ion‐ implantation for nitrogen (35/70/140 KeV) and for magnesium (50/100/165 KeV) in the gallium oxide target is simulated. Lighter ion nitrogen results into more ionization of gallium oxide compared to heavier magnesium ions for the same projected range. Simulation results show that a total energy of 142 KeV (57.96%) of nitrogen ion is lost during ionization process, whereas, for magnesium ion, the total energy loss is 89.49 KeV (28.41%) during ionization.


The challenge is to detect, analyze and process slow frequency variations in acoustical cues obtained after a time-frequency analysis. Modulation frequencies of speech between 2 and 16Hz and especially around 4Hz are of great importance for intelligibility [1]. They carry essential syllabic information. On a physiological side, the phase information is also important because of its influence on the human hearing system. The ability to jointly work on these slow modulation frequencies and their phase data is thus crucial for speech and musical acoustic signals.


This graduate class is designed as a Ph.D.-level overview of international political economy (IPE), with an emphasis on the advanced industrial countries. It also serves as preparation for the IPE portion of the International Relations general exam. The syllabus is divided into three sections: international trade; international monetary and financial relations (including foreign direct investment); and "other topics." An important goal of the course is to use economic theories to identify the welfare effects, distributional consequences, and security implications of foreign economic policy decisions, and to use the tools of political science to analyze how interest groups, voters, political parties, electoral institutions, ideas, and power politics interact to shape policy outcomes. It is our hope that this course will spark your own research ideas and ultimately lead to successful dissertations, publishable papers, and thoughtful pedagogy at the undergraduate and graduate levels.


This makes it urgent to create a modern public administration system within communities that is able to recog-nize the causes of emerging problems, respond to them in a timely manner, prevent negative trends and encourage community members to work for the common good, including by allocating special budget funds for farming development and others types of entrepreneurship in OTG.


The invention discloses a rodless internally-mounted integrated broadband dynamic cylinder which comprises a dynamic cylinder body, an end cover and an integrated speed-displacement sensor; a piston is arranged in the cavity of the dynamic cylinder body; an oil inlet channel and an exhaust channel which are communicated with the cavity and are respectively arranged on both sides of the piston are arranged on the dynamic cylinder body; the exhaust channel is connected with an exhaust valve; the end cover is arranged on one end of the dynamic cylinder body and seals one end of the cavity; the integrated speed-displacement sensor is arranged on the other end of the dynamic cylinder body and seals the other end of the cavity; and a connecting rod of the integrated speed-displacement sensor extends into the cavity and is connected with the piston. According to the rodless internally-mounted integrated broadband dynamic cylinder, a structure without any piston rod is adopted, so that the size of the whole dynamic cylinder is very small; and because no piston rod is adopted, the friction and the leakage at the piston rod do not exist. According to the rodless internally-mounted integrated broadband dynamic cylinder, because the integrated speed-displacement sensor is adopted and arranged on one side of the dynamic cylinder, the overall size of the dynamic cylinder is smaller.


Depletion modeling of fuel assembly with different integral fuel burnable absorber loadings containing enriched boron has been performed by WIMSD transport code. Equivalent boron concentration that represents depletion of the integral fuel burnable absorbers containing enriched boron has been calculated using modified PSU/LEOPARD code. The calculated equivalent boron concentrations have been introduced into FUMACS computer code package master files, upgrading the code package with new global calculation feature for core modeling with different integral fuel burnable absorber loadings containing enriched boron. This new feature of FUMACS/FEEC2001 code package has been verified and validated on 12-month and 18-month operating cycle core loading patterns of NPP Krsko.


The paper introduces the development and establishment of the technology of animal cellculture in vitro,and specially focus on several common ways of the animal cellculture The application of this technology in the life science is also discussed


Findings from the first known trial to investigate synaptic density in living humans instead of post-mortem brain tissues could help expedite the understanding of the pathophysiology of Alzheimer's disease, leading to the development of new treatments, according to a report published July 16 online in JAMA Neurology. Utilizing positron emission tomographic (PET) imaging, researchers at Yale University School of Medicine compared the binding of synaptic vesicle glycoprotein 2A in individuals with Alzheimer's to cognitively normal participants. They found that, compared with age-matched, cognitively unimpaired elderly participants, those with Alzheimer's had a significant 41-percent reduction of hippocampal synaptic densities. Synaptic damage related to toxic amyloid-beta oligomers appears in the earliest clinical stages of Alzheimer's, when patients with mild cognitive impairment exhibit loss of synapses and synaptic proteins. "Thus," the authors wrote, "the ability to assess synaptic density in vivo would greatly enhance clinical research in Alzheimer's and would specifically provide a valuable biomarker outcome for therapeutic trials." Although PET imaging is commonly used to measure glucose metabolism in Alzheimer's studies, the authors emphasized the need for new molecular targets, particularly to assess synaptic density. "We wanted to demonstrate that we can quantify the loss of synaptic density in the living brain by imaging. In the past, synaptic density could only be evaluated by postmortem pathology," lead author Ming-Kai Chen, MD, PhD, associate professor of radiology and biomedical imaging and co-medical director of the Yale University PET Center, told Neurology Today. The study was a collaboration between the department of radiology and biomedical imaging and the department of psychiatry. Dr. Chen added that the team of investigators is already applying this research to gauge the efficacy of novel therapeutics. In a current trial, they are monitoring patients with Alzheimer's at baseline after administering medication. The goal is to track the preservation or potential restoration of synaptic density, he said. While it's too early to implement this approach in clinical practice, Dr. Chen noted that several colleagues are using this biomarker to study other neuropsychiatric conditions, such as Parkinson's disease, schizophrenia, seizure disorder, and autism.