Successful radiotherapy treatment depends on the absorbed dose evaluation and
 the possibility to define metrological characteristics of the therapy beam.
 Radiotherapy requires tumor dose delivery with expanded uncertainty less than
 ±5 %. It is particularly important to reduce uncertainty during therapy beam
 calibration as well as to apply all necessary ionization chamber correction
 factors. Absorbed dose to water was determined using ionometric method.
 Calibration was performed in reference cobalt beam. Combined standard
 uncertainty of the calculated absorbed dose to water in 65 MeV proton beam
 was ±1.97% while the obtained expanded uncertainty of absorbed dose for the
 same beam quality was ±5.02%. The uncertainty estimation method has been
 developed within the project TESLA.


The most important advantages of the artificial neural network (ANN) are the flexibility to model the nonlinear problems and the capability to approximate any functions with highdimensional data requiring no detailed information about the system. In this study, three efficient yet accurate ANN models have been successfully developed to predict the fluid properties of China RP3 kerosene at supercritical pressure by applying the ANN method and the principle of Extended Corresponding State (ECS). The analysis shows that the properties of kerosene predicted by the trained ANN models agree well with the calculated results of the ECS by SuperTrapp. The correlation coefficients (R) between ANN prediction and ECS calculation by SuperTrapp are higher than 0.99, and most relative errors are lower than 0.1%, while the speed of ANN prediction is several orders (arriving at 10) higher than ECS calculation by SuperTrapp, especially near the critical point. Additionally, the performance of the trained ANN coupling with CFD modelling was analyzed as well in this study and exhibited a good result.


BACKGROUND: Until recently, the three-level system of medical rehabilitation adopted in Russia assumed the implementation of each of the stages in various medical organizations. The lack of funding within the budget and the basic compulsory medical insurance program led to limited access for patients to the trajectory of the completed cycle of medical rehabilitation after surgical interventions, which reduced the effectiveness of the provision of profile high-tech medical care. AIM: is to demonstrate the effectiveness of the system for organizing rehabilitation care for patients after arthroplasty of large joints of the lower extremities in a stationary (second) stage in a medical rehabilitation center. MATERIALS AND METHODS: The data of the medical information system on patients treated for three months at the second (inpatient) stage after arthroplasty of the hip and knee joints in the conditions of the Medical Rehabilitation Center were used. The effectiveness of rehabilitation was assessed by tests and scales: rehabilitation routing scale (RRS), visual analog scale (VAS), Borg exercise tolerance scale, Hospital anxiety and depression scale (HADS), European quality of life questionnaire (EQ-5D); Medical research scale (MRS), index Leken. RESULTS: 308 patients (306 operated) were treated after medical rehabilitation measures at the first stage with a RRS score of 4–5 points, of which about 80% ― after primary and revision arthroplasty of large joints. Upon completion of rehabilitation measures, a statistically significant improvement in all functional indicators was noted. Despite the ambiguous opinion of scientists about the need for inpatient rehabilitation after arthroplasty, according to our data, arthroplasty and the subsequent stage of medical rehabilitation using modern technologies in a hospital significantly improve the clinical status, reduce or eliminate pain, increase motor activity, improve the psycho-emotional background and the patient's quality of life. Stationary (second) stage of rehabilitation was effective in 100%. CONCLUSIONS: The results of the work of the medical rehabilitation center proved its organizational feasibility, clinical effectiveness and advantages: continuity and phasing of rehabilitation in a single institution; continuity of observation of the patient during the interaction of multidisciplinary rehabilitation team with the participation of the operating surgeon, an anesthesiologist-resuscitator. The quality of rehabilitation is improved by the concentration of high-tech therapeutic and regenerative agents and experienced specialists, the correction of concomitant pathology, explanatory work with patients to increase compliance.


In order to improve the accuracy of time transfer of RNSS(radio navigation satellite system),a novel closed loop method of Kalman filtering was proposed to estimate the clock offset,clock shifting and clock aging rate,so as to predict the clock bias between user time and system time at the next sampling time,and the design of Kalman filtering was given.Moreover,the situation of single satellite and multiple satellites were both discussed,theoretically proving that the performance of time transfer can be improved by using multiple satellites,and Cramer-Rao bound was presented as well.Finally,the threee-dimension position and velocity of each satellite were generated by STK.User clock model and observation error model were set up to simulate the method in the condition of single satellite and multiple satellites.The result indicates that the accuracy of time transfer can be kept even under heavy noise situation.


A study of the use of car and public transport among residents in 30 residential areas in Greater Oslo indicates that urban planning variables have a significant influence on the energy use per capita for local transport. Residents in local communities with a high density and a short distance to downtown Oslo travel considerably shorter distances and use considerably less energy per capita than those who live in low-density, outer areas. This is true also when the effects of other variables are neutralized. The influence of urban planning variables on the modal split is lower than on energy use. The distribution between public and private transport is influenced most of all by car ownership.


With accelerating urbanization, much more is required of the urban parks and green belts. This paper presents a case study of the planning and designing of the Xiu Hu Park in Chongqing's Bishan District to illustrate how to apply the theory of "Leisure, Culture and Natural Mountain Forests" in the planning and designing of modern comprehensive parks.


Abstract The article focuses on investigating pre-service teachers' expectations of their future teaching career, in particular concerning teacher–student interrelations. In an attempt to comprehend why people choose teaching as a professional career, a conceptual model titled 'Teachers' altruistic-narcissistic classroom expectations' was designed and tested. The model puts forward for consideration the idea that pre-service teachers view their future relations with students as being based on four basic psychological foundations: genuine altruism, paternalistic altruism, benevolent narcissism, and genuine narcissism. A study to test for the validity of this model, using Facet Theory and smallest space analysis as the methodological approach is reported. One hundred and sixty student–teachers participated in the study. The findings provided evidence in support of the model's validity. It is argued that altruism and narcissism conjointly may be regarded as factors motivating people to opt for teaching as a career, and that altruistic and narcissistic expectations can predict teachers' classroom behavior.


Graphic design is no longer a simple way of visual communication and it has become a culture.The paper tries to explore Chinese auspicious culture in graphic design in the view of the usage and transfer of the symbolic in Chinese auspicious culture.It also states that the exploration of the humanism in Chinese auspicious culture has a magnificent influence at present.


This paper documents the use of Broadcast News test materials in DARPA-sponsored Automatic Speech Recognition (ASR) Benchmark Tests conducted late in 1998. As in last year's tests [1], statistical selection procedures were used in selecting test materials. Two test epochs were used, each yielding (nominally) one and one-half hours of test material. One of the test sets was drawn from the same test epoch as was used for last year's tests, and the other was drawn from a more recent period. Results are reported for two types of systems: one (the "Hub", or "baseline" systems) for which there were no limits on computational resources, and another (the "less than 10X realtime spoke" systems) for systems that ran in less than 10 times real-time. The lowest word error rate reported this year for the "Hub" systems was 13.5%, contrasting with last year's lowest word error rate of 16.2%. For the "less than 10X real-time spoke" systems, the lowest reported word error rate was 16.1%. Results are also reported, for the second year, on non-English language Broadcast News materials in Spanish and Mandarin.


The substitution of Re into Bi2O3 allows stabilization of the d- Bi2O3 structure by additional substitution of lutetium ion to give phase of composition Bi12.5Lu1.5ReO24.5. The phase was synthesized for the first time. Structural analysis performed by neutron diffraction showed that space group was Fm3m with lattice parameter a = 5.5591(2) {\AA}. The phase has been found to show high ion conductivity at moderate temperature. The conductivity was measured in the temperature range of 600-800 K. The conductivity of Bi12.5Lu1.5ReO24.5 at 800 K is the same as the conductivity of BiCuVOx, Bi12.5Ln1.5ReO24.5 (Ln = Eu, La, Nd) phases. In this connection the Bi12.5Lu1.5ReO24.5 phase offers excellent potential for moderate temperature application.


Internal atmospheric waves interact with themselves and/or with the undisturbed atmospheric flow, creating very complicated dynamical system with long-range dependencies. We suspect that regional character of the atmosphere at tropospheric heights may be crucial for explanation of the three different dependencies of foF2 on F10.7cm. We employ multivariate statistic methods applied to daily observational data which were obtained using mid-latitude ionosondes for the investigation of these relationships.


This year (1991) the American Petroleum Institute (API) completed the cycle of updating all three of the core evaporative loss publications that deal with aboveground storage tanks. These publications deal with evaporative losses from External Floating-Roof Tanks (EFRTs), Internal Floating-Roof Tanks (IFRTs) and Fixed-Roof Tanks (FRTs). The updated API evaporative loss publications are the result of an extensive API-sponsored laboratory and field testing program that included analytical developments to model storage tank evaporative loss processes


The excavation and support process simulation of a diversion tunnel is a 3-dimensional space problem.The internationally advanced PLAXIS program is used to compare the simulation analysis results with the actual excavation condition of the diversion tunnel so as to have a better understanding of law of stress distribution and deformation of surrounding rocks during construction of the diversion tunnel so that both excavation and support of underground caverns and chambers can be guided in a better way.


While the direct biological factors underlying the progression of GBM, an aggressive form of brain cancer, have been extensively studied, emerging evidence suggests that indirect biological triggers, such as traumatic brain injury (TBI), may also have a role. Since reactive astrocytes are associated with TBI, and astroglial cells are the source of proteoglycans which contribute to changes in biophysical characteristics (stochastic topography, stiffness) of the brain, we postulated a role for stochastic nanoroughness in the induction of glioma. Using a model system to emulate such physical cues, we demonstrate that human cortical astrocytes undergo spontaneous organization into spheroids in response to nanoroughness and retain the spheroid phenotype even upon withdrawal of the physical cues. Furthermore, spheroids serve as aggregation foci for naïve astrocytes; express activated MMP2, and disseminate upon implantation in mouse brain. RNA-seq revealed a tumoral phenotype with a gene expression pattern involving p53, ADAMTS proteases and fibronectin. Moreover, nanoroughness mediates a cross-talk between cancer cells and astrocytes through induced senescence. These findings implicate a role for stochastic biophysical cues in driving a potential malignant transformation of astrocytes.


Old fashioned prejudices have been driving our fight against obesity in the wrong direction. I have long thought so and now, at last, there is evidence.


The present invention relates to an electrochemical energy storage device (10). To ensure a particularly safe working and a from the energy storage (10) to reduce outgoing risk potential, the energy store (10) comprises a cell space for at least partially accommodating an anode and a cathode, wherein the cell space at least partially by a housing (12) is separated from the external environment, and wherein the energy storage device (10) is at least partially provided with a coating (14), wherein the coating (14) is expandable by application of heat.


The present invention relates to a salt or ester which is acceptable to a compound of formula I, a pharmaceutically thereof: Formula I Formula A Wherein R X The invention also relates to their use for the treatment and / or prevention of diseases which are modulated by pharmaceutical compositions, their preparation and PPARδ and / or PPARα agonists containing such compounds.


Model-clone detection is a relatively new area and there are a number of different approaches in the literature. As the area continues to mature, it becomes necessary to evaluate and compare these approaches and validate new ones that are introduced. We present a mutation-analysis based model-clone detection framework that attempts to automate and standardize the process of comparing multiple Simulink model-clone detection tools or variations of the same tool. By having such a framework, new research directions in the area of model-clone detection can be facilitated as the framework can be used to validate new techniques as they arise. We begin by presenting challenges unique to model-clone tool comparison including recall calculation, the nature of the clones, and the clone report representation. We propose our framework, which we believe addresses these challenges. This is followed by a presentation of the mutation operators that we plan to inject into our Simulink models that will introduce variations of all the different model clone types that can then be searched for by each respective model-clone detector.


A hazard classification scheme for identifying hydrogeomorphic hazards for forest management on fans was developed over the period 2000–2004 in west central British Columbia. The scheme involves predictive hazard models, aerial photographic features, site features, and management recommendations. The scheme is based on sampling of 65 fans: 10 in a natural state and 55 with some degree of forest management on the fan (the associated watersheds did not have forestry activity). During 2003–2004 the predictive models were tested on 51 randomly selected fans in the Bulkley Timber Supply Area, and reconnaissance sampling in other areas of the province was undertaken to determine the applicability of the scheme. The objective during 2004–2005 was to undertake extension and produce publications for forest practitioners and the scientific community.


Abstract In this paper, the problem of automatic data clustering is treated as the searching of optimal number of clusters so that the obtained partitions should be optimized. The automatic data clustering technique utilizes a recently developed parameter adaptive harmony search (PAHS) as an underlying optimization strategy. It uses real-coded variable length harmony vector, which is able to detect the number of clusters automatically. The newly developed concepts regarding "threshold setting" and "cutoff" are used to refine the optimization strategy. The assignment of data points to different cluster centers is done based on the newly developed weighted Euclidean distance instead of Euclidean distance. The developed approach is able to detect any type of cluster irrespective of their geometric shape. It is compared with four well-established clustering techniques. It is further applied for automatic segmentation of grayscale and color images, and its performance is compared with other existing techniques. For real-life datasets, statistical analysis is done. The technique shows its effectiveness and the usefulness.


The aim of this qualitative study is to examine and analyze the importance that professionals believe treatment has in relation to creating relationships with patients that are mentally ill. We have been in contact with two organizations working for the psychiatric outpatient care, where we interviewed five professionals individually. The professionals were first given the opportunity to introduce their definition of the concept "mental illness" as well as the target group they are working with. Thereafter the professionals explained the importance of the initial treatment of their patients. Finally, they highlighted the factors that they believe important when it comes to establishing a relationship with the patients. In this study, we have used "categorization" and "trust" as two theoretical tools. In the analysis it appears that professionals should avoid being influenced by the society's generalization of persons with mental illness. In their professional roles, they should instead get to know every patient individually. The initial treatment can be critical for the patient's following treatment process. The professionals' point out that good treatment is when the patients' are involved in their own treatment. When a good meeting is accomplished, a mutual relationship can be created between the professional and the patient.


Fracture toughness (KIC) tests have been carried out on single edge precracked beam specimens with dimensions in accordance with ISO15732 requirements for two types of zirconia and one type of alumina, i.e. ZrO2 -1, ZrO2 -2 and Al2O3. Experimental determinations of KIC for the two zirconia and one alumina materials are 12.18 MPa•m1/2, 16.35 MPa•m1/2 and 4.99 MPa•m1/2, respectively. The median rank method is used to calculate the probability of fracture, F(KIC) of the three cermaic materials for representing the experimental results. The SEM analysis on fracture surfaces of ZrO2-1 materials is carried out, which indicates the fracture in ZrO2 -1 material occurred at the interior of the grain associated with interior stress distribution with principal components of ZrO2 and SiO2. Th extended finite element method (XFEM), based on the linear elastic fracture mechanics in conjuciton with a bilinear traction-separation damage law, is used to simulate the progressive crack growth process in the SEPB specimens. The XFEM predicted KIC results are compared with the corresponding experimental data. The XFEM approach overpredicts the KIC values, from 10.4% to 25.6%, for the three ceramic materials. The possible reasons, in the aspect of loading conditions and contact assumptions, for the difference between the predicted and tested results are also discussed.


Objective In order to conduct a preliminary research to quantify and objectify the characteristics of cervical positioning rotating manipulation,This experiment digital description of mechanical parameters. Methods Invite a has more than 20 years of clinical experience of chiropractors to 25 men aged between 18 to 36 healthy volunteers for2 cervical rotation pull localization operation. Application of three dimensional measuring force platform acquisition technique the performer foot kinetic parameters in the process of operation. High-speed application infrared light spot motion capture system to collect the performer and the subjects in the process of manipulation kinematics parameters.Results The average plantar force is 59. 77 N. The subjects: the average of pull phase forward bend angle is 3. 73°,the average lateral flexion angle is 0. 50°,and the average rotation angle is 10. 20°,instantly pull time about 0. 1016 seconds. Conclusion Cervical rotation is a comprehensive proneness of lateral flexion and rotation process,fully embodies the controls,slightly increasing the amplitude and instantaneousness during the cervical rotation.


Abstract The effect of the nature of planar fragments and substituents located at tri- and tetracoordinated phosphorus atom the conformational behavior of 8-membered cyclic systems are established. 4,5,7,8-Dibenzo- and dinaphto-1,3,2-dioxaphophocines with variable exocyclic substituents are considered by means of different physical methods (dynamic NMR spectroscopy 1H, 13C, 31P, dipole moment, Kerr effect). The classification and quantitative description of the conformations (ring atoms coordinates, Cremer-Pople parameters and torsion angles) was carried out using the Cremer-Pople and Palyulin-Zefirov approach. In this way the following set of four canonical conformations of 8-membered rings with two planar fragments is defined: boat-chair (BC), boat-boat (BB), boat (B) and twist-boat (TB). A tendency toward the equilibrium existence of BC and/or BC and B-forms is found for 4,5,7,8-dibenzo-derivatives and of B-forms for its 4,5,7,8-dinaphto-analogues.


In order to realize interactive selection of arbitrary point in 3D geological model and based on the functions provided by OpenGL,an auxiliary segment sliding bar method is put forward.According to this method,a 3D spatial line corresponding with the 2D screen point caught by mouse should be calculated firstly.Then the line is used to intersect with 3D geological model,and an auxiliary selecting segment consisting of intersected strata is acquired.By setting a sliding bar freely moving along auxiliary segment,arbitrary interactive selection of 3D spatial point in 3D geological model is realized.Practical experiment shows this method is precise and flexible,and can meet the needs of 3D interactive visualization and spatial analysis of geological model.


Subprime lending has become the penultimate case st udy for critics of the recent period of financialization, or neo-liberalism more broadly, b ecause it exposes the most profligate tendencies of predatory lending and the pernicious social costs visited on society's most vulnerable groups. This article builds on the socia l stratification and wealth accumulation literature. We assess how mounting debt levels and crippling costs of servicing these debts compared to relatively flat income growth for femal e-headed households have resulted in wealth (dis)accumulation. We use the Survey of Cons umer Finances (SCF) to analyze how single female-headed households, and in particular how African American single mothers were affected by the subprime boom in different, ar gu bly more pernicious, ways. There is already considerable evidence showing that subprime lending was disproportionally sold to women, particularly minority women. Focusing on sin gle mothers reveals important gender and racial dimensions of the lending techniques, bu t it also shows how marginalized families increasingly relied on housing wealth (equity) to a djust to shrinking purchasing power. Thus, contrary to the lofty expectations of the ownership society, the high mortgage debts of many low-income women suggest they own a lesser share of their homes – (dis)accumulation of wealth – than at any previous time.


There are many different interactions between the fauna on a corpse, such as competition between or predation on the larvae of necrophagous species of Diptera [1–3]. Competition is more common than predation [4]; but when these two phenomena occur at the same time, that is to say where a predator kills and eats its competitors, this process is called intraguild predation (IGP) [3]. IGP can take place between individuals of the same species, or between individuals of different species; and on carcasses, IGP should be taken into account in the estimation of post-mortem interval based on the entomological evidence, but at present few reports about forensic cases of this nature have been published. Besides being forensic indicators, Synthesiomyia nudiseta (van der Wulp, 1883) (Diptera: Muscidae) and Chrysomya albiceps (Wiedemann, 1819) (Diptera: Calliphoridae) are facultative predatory species during their last larval instar [5–7]. Both species are forensic indicators in southwest Europe, being early colonizers in autumn, C. albiceps peaking in September and S. nudiseta in November [8]. The predatory behaviour by C. albiceps is well-known [6, 9–11], but it is not the case of S. nudiseta; however, the predatory behaviour on other Diptera larvae of this muscid was recently confirmed. Ivorra et al. [5] studied the combination of these species in the laboratory at the same time and trophic medium, and the rate of predation by S. nudiseta was found to be higher than that by C. albiceps; more recently, the prey-predator interaction between them without food was studied by Barbosa et al. [12]. However, it is important to know how the interaction between these species on human remains could affect the post-mortem interval estimation. So, due to the importance of knowing the predatory behaviour of these species in estimating the date of ABSTRACT


, i i i . The d e g r a d a t i o n o f p h e n y l a l a n i n e and t y r o s i n e was examined i n a x e n i c c u l t u r e s o f I s o c h r y s l s g a l b a n a Parke and N a v l c u l a l n c e r t a H u s t e d t . B o t h s p e c i e s were a b l e t o m e t a b o l i z e L p h e n y l a l a n i n e and L t y r o s i n e as t h e s o l e n i t r o g e n s o u r c e , but s e v e r e growth I n h i b i t i o n was o b s e r v e d f o r _ I . g a l b a n a . No growth o f I_. g a l b a n a was o b t a i n e d on the D-isomers of t h e s e two amino a c i d s , but N. l n c e r t a was a b l e t o u t i l i z e b o t h Damino a c i d s a f t e r an extended l a g p e r i o d . A n a l y s i s o f t h e growth medium and t h e a l g a l c e l l s f r o m n o n r a d i o a c t i v e and r a d i o a c t i v e e x p e r i m e n t s n e v e r r e v e a l e d c i n n a m i c o r p-coumaric a c i d s . T h i s s u g g e s t e d t h a t p h e n y l a l a n i n e and t y r o s i n e ammonia-lyases (PAL and TAL) were not i n v o l v e d i n the i n i t i a l d e g r a d a t i v e s t e p o f e i t h e r t h e s e amino a c i d s . T h i s was c o n f i r m e d as no e n z y m a t i c a c t i v i t y f o r PAL was d e t e c t e d i n c r u d e enzyme p r e p a r a t i o n s . E n z y m a t i c a c t i v i t y f o r amino a c i d t r a n s a m i n a s e was obt a i n e d f o r b o t h a l g a l s p e c i e s . T h i s s u g g e s t e d t h a t p h e n y l p y r u v l c a c i d and p h y d r o x y p h e n y l p y r u v i c a c i d were t h e I n i t i a l r e s p e c t i v e p r o d u c t s from t h e m e t a b o l i s m o f p h e n y l a l a n i n e and t y r o s i n e . From t h e n o n r a d i o a c t i v e and r a d i o a c t i v e e x p e r i m e n t s , a scheme f o r t h e d e g r a d a t i o n of L p h e n y l a l a n i n e and L t y r o s i n e was p r o p o s e d f o r b o t h a l g a l s p e c i e s . The compounds i n b r a c k e t s were not i d e n t i f i e d but were e x p e c t e d . The pathways were: L p h e n y l a l a n i n e — p h e n y l p y r u v l c a c i d >-[phenylacetaldehyde] — y p h e n y l a c e t l c a c i d — ^ m a n d e l i c a c i d — ^ b e n z o y l f o r m l c a c i d — ^ > [ b e n z a l d e h y d e ] b e n z o i c a c i d — * p h y d r o x y b e n z o i c a c i d ; and


This project is the my sound-body project series using my own voices as information of individual. By recording and processing voices and dismantling them into the presences of mysterious creatures, imaginary climatic phenomena, noises, etc., the voices (individual Information) are extended as stereophonic phenomena into the space, and reconstructed figure of myself as a supernatural / unrealistic presence will appear in the public space (such as factory or natural surroundings or dark room) in concert with the specific space. By installing a number of speakers in the forest (natural environment), recorded voices of my own that is transformed into the surrounding sounds like howls of animals, singing of insects, whisper of the leaves via computer programming will be exhibited at the site. My own body (concrete presence) is not there, but the transformed sounds of my voice turned into the voice of insects, and those sounds that become the phenomenon are installed into the space as a sound scape in concord with the exhibition space, changing all the atmosphere.


Millimeter-wave tracking radars should be operated in various environmental restrictions, thus they demand more computing power and smaller size compared to conventional tracking radars. This paper presents the design and implementation of the compact power supply for millimeter-wave tracking radar applications. To meet requirements of low voltage/high current and voltage accuracy for FPGA/DSP digital circuits, Point of Load (POL) converters are used in order to enhance power density and system efficiency. LDO (Low Dropout) is applied for the output voltage under the light load condition, then the single-input-multi-output power supply with max power of 375 W and 8 outputs is developed. The proposed power supply achieves output voltage accuracy of ±2 % and noise level of <50 mVpp % under full load conditions.


The objective of this study was to determine the number of days and degree-days in which panicle initiation (PI) takes place before panicle differentiation (PD) for rice cultivars with different developmental cycle duration. A field experiment was carried out in a lowland area, in Santa Maria, RS, Brazil. The experiment consisted of three sowing dates and four rice cultivars ('IRGA 421', 'BRS Querencia', 'IRGA 424' and 'SCSBRS Tio Taka') during two growing seasons (2011/12 and 2012/13), in a complete randomized block design with four replications. The date of PD was estimated from the tables contained in STEINMETZ et al. (2010) and around 14 days before the estimated date of PD. Ten plants were sampled daily to determine PI in a laboratory under a 45 times magnifying glass. After PI, 10 plants were sampled daily to determine PD using the "cotton ball" stage as a marker. Thermal sum was calculated considering the basal temperature of 11oC. The greatest differences between the dates of occurrence between PI and PD were 8 and 6 days, and 116.4 and 73.7oC day. Most of the differences varied between 2 and 8 days, and between 23.8 and 116.4oC day. It was concluded that the maximum period that PI takes place before the PD is eight days, corresponding to 116.4oC day, being influenced neither by sowing date nor by the length of cultivars cycle.


Th e growth in freight-traffi c between Europe and China is driving the quest for new transport routes between these regions. One of the options is to use railway routes. Th e concept of using railway connections is referred to as the New Silk Route. A number of analyses of freight traffi c point to a huge demand for this type of transport since sea freight is marked by seasonality, long travel times and the growing problem of congested ports, both in China and Europe. Currently, there are several railway connections between China and Europe. Th ese connections are hindered by intermodal transport and transhipment, which extend freight travel time, generate extra costs and result in the low capacity of these connections. In order to increase capacity, new connections should be developed using the interoperability of all the railway routes between Europe and China. Many barriers, however, impede this idea. Many of those barriers are technological in nature. Th is paper looks into technological barriers that constrain interoperability in railway transport between Europe and China. Th e fi rst section sheds some light on the idea of interoperability, as well as railway connections between Europe and China. Th e second section points to the technological barriers in this kind of transport. Th e next section presents some possible solutions for removing the barriers. Th e fi nal section provides a summary.


The set M is closed if M=uM. +(M) is the least ordinal number t for which the set utM is closed, that is, uEM=ut+1M. G(P, u) is the set of all ordinal numbers +(M) where MCP. E. Cech3 has posed the following problem: What are necessary and sufficient conditions on a set H of ordinals in order that there exist a topology u in a countable set P for which H=G(P, u)? V. Jarnik4 solved the generalization of the problem for a set of arbitrary cardinal number s&; his topology, however, is not an additive one, as it satisfies only the axiom of monotony. The present paper contains a solution to this problem when u is to be additive; this solution is stated in Theorem 1. The proof is carried through for a class of cardinals including No. First we have to prove the following lemma.


At the end of the sixth century BCE, Hipparchus, the Athenian tyrant, took it upon himself to bring culture (paideia) to the Athenian people. He invited leading artists from all over Greece to come to Athens to perform; he even sent a fifty-oared warship after the famous poet, Anacreon of Teos. In addition, in order to reach those living outside the city center, Hipparchus decided literally to take culture to the streets. He erected Herms (rectangular pillars with a set of male genitalia halfway up and a portrait of Hermes on top) on the roads between the middle of the city and each outlying district on which he had inscribed some verses of his own and other bits of his wisdom: 'Walk with just thoughts' or 'Do not deceive a friend'. According to Plato, Hipparchus erected these Herms for the people in the country 'so that traveling up and down the roads, reading and getting a taste of his wisdom, they might wander [to the city] from the country in order to complete their cultural education (epi ta loipa paideuthesomenoi)'.


A 20.7-31.8GHz dual-mode voltage waveform-shaping oscillator is presented in this paper. Dual-mode voltage waveform shaping resonator is proposed to excite two pairs of resonances, representing fundamental and third-order harmonic in two modes, respectively. Mode-switch-circuits are implemented to allocate specific mode without degrading the Q-factor of the resonator. As a result, the square-like voltage waveform can be obtained in dual-mode to reduce the ISF rms value for lower phase noise and further extend the tuning range. The oscillator is fabricated using a conventional 28nm CMOS technology with the core size of 420µm by 160µm, which exhibits a measured phase noise of −102.46dBc/Hz at 1MHz offset with a carrier frequency of 25.56GHz. A state-of-the-art FoMT of 195.8dBc/Hz is achieved with the wide tuning range of 42.3% and power consumption of 5.5mW.


Because the compressional wave velocity,density and longitudinal wave impedance parameter of reservoir sandstone and mudstone in Sulige Region overlay each other,the post-stack acoustic impedance inversion is difficult to reservoir prediction and fluid identification.Therefore,using the logging data,this paper studies the pre-stack reservoir prediction and fluid identification based on the parametric analysis of seismic rock physics.The results show that the elastic physical parameters can distinguish between sandstone and mudstone,and identify the fluid based on the reservoir or gas sensitive parameters.This study can provide basis for the study of pre-stack reservoir prediction and fluid identification.


Abstract Young people in South Africa are at risk of unplanned pregnancy and sexually transmitted diseases. In efforts to address these reproductive health problems, the dominant focus so far has been on young women. There is an increasing awareness that males need to be involved at all levels of reproductive health, and the importance of researching young men's sexuality has been emphasised. Sexuality researchers also argue for localised understandings of sexuality, because sexuality and sexual behaviour are likely to have different meanings for adolescents living in different communities. This article reports on the qualitative findings of a larger study that aimed to explore the sexuality of young heterosexual males living in a Coloured 1 , semi-rural community in the Western Cape. The focus was on investigating adolescent men's constructions of their own sexuality and the implications for safe sexual behaviour. Social construc-tionist grounded theory was used to analyse interviews conducted with 7 young men between the ages of 16 and 18. It was found that these young men constructed their sexuality as being driven by physiological and social forces. It is argued that such a construction limits their ability to take responsibility for their own and their partners' reproductive health.


A transformer-based, purely sinusoidal, energy-saving controller for induction motors is presented. The controller applies a three-phase transformer in a reconfigurable scheme to create three different voltages. A simple control scheme is then applied to set the 'right voltage' to supply the motor. Significant reductions in the real and reactive power consumption were noticed, especially in motors operated under low load.


For mappings acting from an interval into a locally convex space, we study properties of strong compact variation and strong compact absolute continuity connected with an expansion of the space into subspaces generated by the compact sets. A description of strong K-absolutely continuous mappings in terms of indenite Bochner integral is obtained. A special class of the spaces having K-Radon-Nikodym property is obtained. A relation between the K-Radon-Nikodym property and the classical Radon-Nikodym property is considered.


This thesis is done at Spotify, the music streaming service. For Spotify, income from the ad market becomes more and more important. Thus, to increase revenue, under-deliveries of campaigns needs to be minimized. To do this, mathematical optimization methods have been used, together with already available software in form of a simulator for ad delivery. There is no obvious way to express the goal function analytically, and this introduces problems. To get a value of the goal function, a simulation of the ad delivery needs to be performed. This results in that the value is noisy due to re-sampling of the user base. Two different methods have been tried; the simple approach of only updating the priorities of the campaigns that are under-delivering, and the classic optimization method gradient descent. The hope was to be able to approximate the gradient for gradient descent, and some various methods for that have been tried. The results indicate that the simple approach worked best. The income lost could be lowered by one percentage unit in simulations. With gradient descent no improvements at all could be seen. But further tests should be done to confirm the result.


Semantic segmentation directly from the images of landfills can be utilized in the earth movers to segregate the garbage autonomously. Generally, Various segregation methods are available for garbage segregation such as IOT based waste segregation, Conveyor belt segregation in which none of them are directly from landfills. Semantic segmentation is one of the important tasks that maps the path towards the complete scene understanding. The aim of this paper is to present a smart segregation method for garbage by using semantic segmentation with DeepLab V3+ Model using the framework(Backbone model) of Xception-65 with the mean accuracy of 75.01%. This paper features the segmentation with the GarbotV1dataset which has major classifications such as Plastic, Cart-board, Wood, Metal, Sponge. The paper also contributes a method for reconstructing the segmented images to build a 3D map and this exploits the use of earth moving vehicles to navigate autonomously by localizing the segmented objects.


Transition to Common Work: Building Community at The Working Centre, by Joseph and Stephanie Mancini. Wilfrid Laurier University Press, 2015. xix + 212. Pb., $17.66 ISBN 978-1-77112-160-6


In 1993, Bourgain introduced the Fourier Restriction Spaces, or Xs,b, in order to prove local well-posedness of nonlinear Schrödinger and Korteweg-de Vries type equations, through a contraction mapping argument. By taking advantage of the localisation of the space-time Fourier Transform of the linear solution, and certain properties of the nonlinearity, it led to improvements on previous results. Through the years, the idea was followed by many authors and further developed, leading to the Fourier Restriction Norm Method. We present a selection of known results, for cubic and quintic nonlinear Schrödinger equation, in one dimension, and for Korteweg-de Vries type equation, in the periodic setting. In particular, we focus on linear estimates for general dispersive equations, and proceed to equation specific estimates, such as Strichartz and nonlinear estimates.


To evaluate the pharmacokinetic (PK)/pharmacodynamic (PD) and safety profile of dapagliflozin in paediatric patients aged 10–17 years with type 2 diabetes mellitus (T2DM).


Purpose – Organizational citizenship behavior (OCB) has received much attention in the past decade as scholars have recognized its significant impact on the success of organizations. The current study seeks to enrich our understanding of citizenship behavior in the school setting by identifying the main factors that may enhance this behavior among teachers.Design/methodology/approach – Specifically, the paper examines the direct effect of teachers' participation in decision making (PDM) on their OCB, and the impact of teacher empowerment, as a mediating variable, on this relationship. Data were collected from 983 teachers in 25 junior and 27 senior high schools in Israel.Findings – Hierarchical regression analyses revealed that teacher empowerment played an important role in mediating the relationship between teachers' PDM and OCB. Involvement in decision‐making processes induces teachers to take on new roles and have a more direct impact on school life, which in turn might lead them to invest extra effor...


Toxicity assays indicated that when diflubenzuron (DFB) was topically applied on larvae of the Egyptian cotton leafworm, Spodoptera littoralis (Boisduval), and the beet armyworm, Spodoptera exigua (Hübner), estimated LD50 values were similar, reaching 0.47 and 0.44 ng/larva, respectively. This study evaluated the importance of the rate of uptake and excretion, and of enzymatic metabolism in building up an insecticidal toxicity after topical application on the insect cuticle in both species. In general, penetration of DFB in S. littoralis was about 2‐fold higher than in S. exigua, whereas metabolic breakdown was of minor importance in S. littoralis as compared with S. exigua. The current data indicate the importance of cuticle penetration and discuss that extrapolation from oral feeding toxicity results to topical toxicity data should be evaluated with caution, especially for insect growth regulators used in integrated pest management.


Among the oldest words of any language are the names of rivers and mountains. In Western Europe these are commonly from the ancient Celtic language from which Welsh is derived. Apart from Basque, Welsh is the oldest living language of Western Europe, and Welsh speakers can often see the link between the old Celtic tongue and the names of waterways and land formations. …


Corynebacterium glutamicum was engineered to produce glutaric acid by metabolic engineering approaches starting from the heterologous introduction of glutaric acid biosynthesis pathway by the expression of Pseudomonas putida davT, davD,...


The powder-in-tube (PIT) technique was used to fabricate multifilament (Mpb)Nr2Ca2Cu30 y (Bi-2223) superconducting tapes. Transport current properties of these tapes were enhanced by increasing the packing density of the precursor powder and improving the mechanical deformation condition. A critical current (Ic) of> 35 A in long lengths (> 200 m) tapes has been achieved. In measuring the dependence of critical current density on magnetic field and temperature for the optimally processed tapes, we found a Jc of >104 A/cm2 at 20 Kin magnetic fields up to 3 T and parallel to the c-axis, which is of interest for use in refrigerator-cooled magnets. Ic declined exponentially when an external field was applied perpendicular to the tape surface at 77 K. Mechanical stability was tested for tapes sheathed with pure Ag and Ag-Mg alloy. Tapes made with pure Ag sheathing can withstand a tensile stress of =20 MPa with no detrimental effect on ~ values. Mechanical performance was improved by using Ag-Mg alloy sheathing: values of transport critical current began to decrease at the tensile stress of = 100 MPa. Transport current measurements on tapes wound on a mandrel of 3.81 cm (1.5 in.) diameter at 30° to the longitudinal axis, showed a reduction of =10% in Ic values for pure Ag-sheathed tapes and 5% reduction in IC values for Ag-Mg sheathed tapes, compared with the Ic values of as-coiled tapes. *This work was supported by the U.S. Department of Energy (DOE), Energy Efficiency and Renewable Energy, as part of a DOE program to develop electric power technology, under Contract W-3 l-109-Eng–38.


An apparatus and method for a shift control of a vehicle are provided. The apparatus includes a road information obtaining unit that obtains road information of a road on which the vehicle is traveling and traffic information and a front vehicle detection unit that obtains front vehicle information including a speed of a front vehicle. A running state obtaining unit obtains an average running speed of the vehicle and determines whether the vehicle is traveling at a high constant speed based on the road information, the traffic information, and the average running speed. A shift controller adjusts a shift time of a transmission based on the front vehicle information when braking occurs during high constant speed traveling of the vehicle.


My type is in the British Museum, where it has been examined by M. Ragonot, who compares it in his description with the European D. abietrella, from which this authority finds it to differ structurally. The figure in M. Ragonot's magnificent work seems to me excellent. I take this occasion to express my dissent from the classifaction adopted in the Philadelphia List.


ynthetic index funds provide exposure to the equity markets and replicate the return of a S benchmark index. Unlike the traditional type of index fund, which is normally invested in stocks, synthetic equity index funds invest in derivative products namely, stock index futures contracts. Synthetic index funds based upon the U.S. equity markets have been available to investors since introduction of the S&P 500 futures contract at the Chicago Mercantile Exchange (CME) in 1982. A more recent development allows investors to gain exposure to the international equity markets through the use of derivatives: futures contracts on foreign equity indexes. The Commo&ty Futures Trading Commission (CFTC) has approved several of these locally traded foreign index futures contracts for U.S. investors and is in the process of approving others. The result of these developments is that, for the first time, global as well as domestic investors can use derivatives to construct synthetic index funds that provide liquid, low-cost exposure to worldwide equity markets.


Niche theory is a theory crihinally applied in species relationshop,which has gone begond bidagy and penetrate many fields.Facing the apenness of distribution field,haw to choose a swifable way for develapment has been a probled for the Chinese retail companies.On the basas of niche theory,the paper analyies the success of SUGUO Supermarket,RONGLE Eletrin Appliances,BEIJING CHENXIAN Warehouse supermarket and so on,invetigates the strategic to achieve enlightening effets on Chinese retail companies.


An unusual incidence of progressive pulmonary tuberculosis occurred in a rural New York high school in which during a two year period 13 of 133 pupils and one of their teachers were found to have the disease. Tuberculosis developed in two additional students in this group and one from the next lower class within the subsequent eight years. Explosive outbreaks of pulmonary tuberculosis among pupils of high school age are rare, although sporadic cases secondary to an active case in a school population are not uncommon. In 1949 Roe and Dick 1 reported the investigation of a school group in which a master and 12 of 342 boys 13 to 17 years of age were discovered to have tuberculosis. They cited reports in the literature of school epidemics of tuberculosis among children under the age of 13, but could find only one report, that of Hyge, 2 concerned with students of


Further studies have been made on a theory on solute transport through a membrane proposed recently by us which predicts two relaxation processes with the slower rate P1 and the faster rate P2 under quasi-steady state conditions. We elucidate the dependence of P1 and P2 upon the volume fractions of the donor, receiver and membrane phases. It is shown that P1 and P2 have extrema when the volume fraction of the donor and receiver phases are equal ;P2 has a minimum but P1 may have either maximum or minimum. We also derive simple approximate formulas for the time course of the solute concentrations in the respective phases.


The reuse and recycling of wastes affect discarded tires too. This paper expounds about a research project carried out in the laboratory to prove the viability of introducing ground tire rubber in paving asphalt mixes. Both the wet and the dry process have been studied by testing the most usual types of asphalt mixes in the Spanish technology. Advantages or disadvantages for every option and latest results obtained in on going projects are described thorough the paper.


Tahiti 4/2020 | Research Articles | Idrobo: The Hermeneutical Value of Bodily Experiences for Art History Research One of the most important paradigms of contemporary art is that of the viewer as an active participant in the experience of the artwork. The range of this participation extends from various degrees of physical engagement to the necessity of the viewer's presence to complete the piece – a key concept being that of activation. While this is perhaps more or less evident in many performances and installations that require at least one or two people, and even more so in artistic projects that involve groups or whole communities, engaging physically with an artwork is nevertheless already part of the moment of reception, regardless of the type of art form. But if one essential requirement for the viewer's physical involvement in the art-making process is to have a haptic expecontribute to the interpretation of artworks from different periods? In this paper, I will examine how this paradigm of the active spectator can be applied to the interpretation of a few paintings, mostly of the nineteenth century. I will argue that the practice and/or observation of bodily movements (in daily life) may contribute to expanding our understanding of the event in the image, and that they can be transformed into reception strategies that nurture interpretation and art research. While these bodily experiences can range from playing a musical instrument to practicing a sport to any other set of practices and activities, this paper will focus only on dancing and walking because of their strong prevalence in visual arts. The first section elaborates further on the idea of the explicit viewer in contemporary art, by contrasting two forms of imagery related to dance movements, namely Andy Warhol's The Hermeneutical Value of Bodily Experiences for Art History Research


Magnetic resonance (MR) images are displayed at low contrast due to the inability of a device to display the complete range of values under a single window. Generic contrast enhancement algorithms cannot be used in MR due to its characteristic variability of voxel values that represent the same object. Consequently, enhancement works better when driven from the viewpoint of application and domain knowledge is used to design the method. In this paper, a method is demonstrated which is dependent on the structure of interest and computes an appropriate window accordingly. The effectiveness of this type of windowing is demonstrated by testing on a cerebellum segmentation task, using a publicly available dataset (IBSR).


The relationship between plant availability and preventive maintenance (PM) is examined. It is concluded that unexpected failures that lead to partial or full plant forced outages are costly events that should be avoided. Plant availability is improved (i.e., forced outages are reduced) in one of two ways: maintain or increase equipment MTBF (mean time between failure) and/or reduce its MTTR (mean time to repair). Preventive maintenance actions, when properly executed, can beneficially impact both MTBF and MTTR. Current PM practices are frequently derived from a series of intuitive processes that are not very effective in meeting the PM program objectives. Reliability-centered maintenance is found to be a proven methodology for optimizing the effectiveness of PM programs, and thus recommended as the preferred approach to defining PM tasks.<<ETX>>


Today, the accelerated degradation of many concrete structures poses a major challenge for the proper maintenance of the transport infrastructure. Therefore, inspection and maintenance operations constitute an important part of the recurrent costs of infrastructure. Furthermore, the increasing migration of population to urban areas has made sustainable development an imperative need. This need has become a driving force for innovation and new challenges such as the concept of smart cities and infrastructure. The successful utilization of newly available technologies will enable a whole new range of possibilities such as sensor driven cloud-based strategies for infrastructure management, which will promote an upgrade of the current infrastructure network to a new generation of safer, more efficient and more sustainable smart infrastructure: the infrastructure 2.0. The aim of this paper is to review the state-of-the-art of the different key technologies comprising a smart monitoring system, focusing on the aspects that are required to ensure a successful implementation of such system. The main result of the study is a scientific roadmap that can serve as a guide for traffic administrations and academic institutions in their task to develop and create a new infrastructure management strategy based on emerging technologies and innovative processes.


In this paper, a novel global optimization algorithm has been developed, which is named as Particle Swarm Optimization combined with Particle Generator (PSO-PG). In PSO-PG, a particle generator was introduced to iteratively generate the initial particles for PSO. Based on a series of comparable numerical experiments, it was convinced that the calculation accuracy of the new algorithm as well as its optimization efficiency was greatly improved in comparison with those of the standard PSO. It was also observed that the optimization results obtained from PSO-PG were almost independent of some critical coefficients employed in the algorithm. Additionally, the novel optimization algorithm was adopted in the airfoil optimization. A special fitness function was designed and its elements were carefully selected for the low-velocity airfoil. To testify the accuracy of the optimization method, the comparative experiments were also carried out to illustrate the difference of the aerodynamic performance between the optimized and its initial airfoil.Copyright © 2014 by ASME


Internal risks caused by managerial decisions play an important role in the management of organizations. Nowadays the relevance of quantitative risk assessment is enhancing that is regulated by the new international standard ISO 9001:2015. This is necessary to correlate the significance of risks and the assessment of their reduction costs. The most convenient way of risk measurement is by means of a two-factor model through the components: the probability of risk emergence and the severity of consequences. The author has analyzed the methods of measuring the specified parameters and proved the application of expert approaches to assessing the probability and severity of consequences under the efficient management. This has allowed to obtain quantitative risk values that are required for accurate comparison of different risks and for the assessment of their reduction costs. Based on the analysis of the approaches to expert assessments the author has formulated methods of determining risk parameters and consequently risks themselves in the organization management. The obtained results have been applied in personnel training in the course of building risk management systems in different organizations. In addition, the top and mid-level personnel have participated in the training as experts.


Photolysis of dibenzyl ketone (DBK) solution at room temperature yields 1,2-diphenylethane and carbon monoxide quantitatively. Results of the study of this reaction, using light and ordinary mercury lamps as excitation sources, show that (1) a measurable, but small, /sup 12/C//sup 13/C isotope separation occurs in homogeneous (benzene) solution; (2) the efficiency of the separation is greatly enhanced in soap solution relative to homogeneous solution; (3) the carbonyl carbon of DBK is specifically and exponentially enriched as photolysis proceeds; (4) an external magnetic field significantly influences the efficiency of the isotopic separation. Mass spectroscopic and NMR analyses of the recovered DBK confirm these conclusions. 2 figures.


The purpose of this study was to explore performance expectancy, facilitating conditions, effort expectancy, and perceived ease to use on the intention of using learning support media. Furthermore, it examined the intention to use learning support media on the commitment to use it. The quantitative method approach was used as a basis for conducting this research. The data source used is primary data, namely questionnaires. The distribution of questionnaires is carried out online through Google Forms. The respondents in the study were 100 respondents with a sampling technique using purposive sampling. Respondents were students who had used learning support media, such as Canva, Kahoot, Zoom, Google Meet, and others. The data analysis tool used SmartPLS. The result of this study stated that performance expectancy, facilitating conditions, effort expectancy, and perceived ease to use had a positive and significant effect on the intention to use learning support media. Moreover, the intention to use learning support media had a positive and significant effect on the commitment to use media support learning.


In this article, we present two online platforms developed for the structuring and valorization of old geographical iconographic collections: a multimodal search engine for their indexing, retrieval and interlinking, and a 3D navigation platform for their visualization in spatial context. In particular, we show how the joint use of these functionalities, guided by geolocation, brings structure and knowledge to the manipulated collections. In the demonstrator, they consist of 54,000 oblique aerial photographs from several French providers (national archives, a museum and a mapping agency).


In this article, the author advocates for the use of causal graphs to modernize the field of factor investing and set it on a logically coherent foundation. To do this, first he introduces the concepts of association and causation. Second, he explains the use of causal graphs and the real (causal) meaning of the ceteris paribus assumption that is so popular among economists. Third, he explains how causal graphs help us estimate causal effects in observational (nonexperimental) studies. Fourth, he illustrates all of the earlier concepts with Monte Carlo experiments. He concludes that the field of factor investing must embrace causal graphs in order to wake up from its associational slumber.


Here we expressed our opinion in respect to an important research area of study, the neuromuscular junction, which historically has been helped the pharmacology with numerous discoveries related to the mechanisms of action of several substances. Venomous animals, toxins, plants and other bioactive compounds can be studied using neuromuscular preparations from mammalian, avian and other species. The kind of information which is possible to extract from the data interpretation is relevant and stickling to this field of study and the teaching of new researchers should be encouraged. In the last twenty years our group has employed neuromuscular preparations for confirming the antiophidian potential of ethnobotanical plant-extracts used in folk medicine, which need scientific validation. In this view, representatives of Brazilian venomous snakes of Crotalus and Bothrops genera, Crotalus durissus terrificus and Bothrops jararacussu, respectively, have been the protagonists for these studies. Besides, other studies are of notorious importance which includes those with Ophiophagus hannah (King cobra) and Phylodrias olfersii, an opisthoglyphous colubrid. Ethnobotanical plants such as Casearia sylvestris ("guacatonga"), Casearia gossypiosperma ("pau-de-espeto"), Curcuma zedoaroides ("Wan-Paya-Ngoo-Tua-Mia"), Camellia sinensis (tea); Dipteryx alata ("baru"), Hypericum brasiliense, Jatropha elliptica ("batata-de-teiu"), Mikania laevigata ("guaco"), Plathymenia reticulata ("vinhatico"), and Vellozia flavicans ("canela-de-ema") had their antiophidian properties confirmed using the neuromuscular junction as biological preparations. In a literatures survey, the majority of studies found in on line data bank, after crossing the words "antiophidian plants and neuromuscular junction" as themes, involves the use of in vitro mouse/rat phrenic nerve-diaphragm (PND), chick biventer cervices (BC) or the in vivo rat external popliteal/sciatic nerve-tibialis anterior (EPSTA) preparations, respectively. Such biological methods were chosen probably because the robustness and sensitivity of the neuromuscular junction to the deleterious effect of snake venoms. In the case of chick BC it has a unique value to the experiment, because the inherent sensitivity to the exogenous application of agonists such as acetylcholine and potassium chloride, which induce a contracture as a response. When the potential for clinical applications are desired, in vivo experiments such as those of EPSTA are relevant, in respect to the involvement of the neuromuscular system in the pharmacological response. In conclusion, this text reflects the potential of an indispensable physiological preparation named neuromuscular junction, which is outstanding to recognize and validate antiophidian ethnobotanical compounds. In this context, Dipteryx alata is a plant that has been studied by our group for a long time, in which neuromuscular preparations were chosen as efficient biological models.


Current-voltage characteristics were investigated in highly anisotropic Bi2Sr2CaCu2O8 + δ, Bi1.8Pb0.2Sr2CaCu2O8 + δ and isotropic (K,Ba)BiO3 single crystals which were irradiated in the direction parallel to the c-axis. In the range of magnetic fields from Bϕ/10 to Bϕ (where Bϕ is the matching field), same scaling functions can be used to describe the transition in those two systems. The field- and sample-independent critical exponents, which were found to be ν⊥ = 1.1 ± 0.1, z = 5.3 ± 0.2 using α( ≡ ν∥/ν⊥) = 2, are in a very good agreement with numerical simulations for strongly screened vortex line interactions. Moreover, the obtained scalings are the same despite a large difference in anisotropy.


Systematic principles for integrating symbolic and subsymbolic processing will be developed in the project. Key aims are to ensure that the resulting total hybrid system retains desirable properties of both processing levels. On the one side the signal processing abilities, robustness and learning capability of neural networks should be preserved. On the other side advantage should be taken of the ability of rule-based systems to exploit high level knowledge and existing algorithms and to explain (to a user) why conclusions were reached in particular cases. The methodologies developed in the project are tested in a challenging multimedia application related to human computer interaction, which is recognition of emotion based on both voice and visual cues. Low level features are extracted from signals using neural networks and subsequent formulation of rules provides a conceptual framework, substantial for emotion analysis.


This article discussed the way that research on the pathophysiology of chronic pain has started to challenge the traditional diagnostic and treatment paradigms for the patient with neuropathic pain. It stated that the heterogeneous nature of neuropathic pain indicated that more than one anatomic lesion is most likely responsible for the clinical presentation of a particular syndrome. Conclude that the current taxonomy often falls short of identifying the multifactorial nature of neuropathic pain syndromes and, therefore, may lead to imprecise management of those conditions. It is suggested that an integrated approach to the diagnosis and treatment of neuropathic pain that considers both etiologic factors and possible mechanisms will lead to more effective taxonomy, treatment paradigms, and outcomes.


Agriculture is one of the most important sphere in the world. It's development is a key question for all countries. Ukraine takes significant part on agricultural markets and has a big potential for future development. In last times, Ukraine is growing its export of agricultural products to the EU-countries. On the world food markets its plant and animal products are taking leading positions and are highly competitive. Ukraine made a big step in agricultural development since 1990th. In present times domestic enterprises developing new technologies and increasing volumes of production and processing. The main key points of Ukrainian agriculture development in described in article. Based on data analyses of FAO, World Bank and State Statistical Service of Ukraine, it was defined main points of increasing the competitiveness of Ukrainian agricultural products on the world market and forecasted its future development based on correlation and regression analysis which can help public and private sector to identify the strategies of cooperation with Ukrainian agricultural producers.


Objective To explore the anti-inflammatory and analgesic mechanism of Composite Qi-ling Tablets (developed from the "Yi-Qi Hua-Yu Bu-Shen Remedy") in established animal model of lumbar disc herniation. Methods The animal model was established using silica gel to simulate the intervertebral disc herniation and thereby causing artificial compression of L5 roots. The anti-inflammatory and analgesic mechanism of Composite Qi-ling Tablets was assessed with ELISA. Results Compared with normal controls, rats with lumbar intervertebral disc protrusion presented with locomotive disorders and elevated malfunction scores (P0.01). Increased levels of PLA2, PGE2 and TXB2, and imbalanced TXB2/6-K-P were found in compressed nerve tissues (both P0.01). Compared with the untreated model group, locomotive dysfunction was significantly improved with Composite Qi-ling Tablets in terms of standing posture, claudication and function score of the left lower limb. The decreased contents of PLA2, PGE2 and TXB2 (P0.01) and imbalance of TXB2/6-K-P resumed to normal (P0.01). Conclusion Silica gel compression of the L5 nerve root can lead to massive release of inflammatory mediators, such as PLA2, PGE2, TXB2 and imbalance of TXB2/6-K-P. Yi-Qi Hua-Yu Bu-Shen Remedy appeared to relieve the locomotive dysfunction among animal models of lumbar intervertebral disc protrusion through effective reduction of inflammatory mediators and regulation of TXB2/6-K-P balance.


In cardiac patients with prolonged hypertension, it can increase the occurrence of diastolic dysfunction or systolic dysfunction which ultimately causes heart failure. LVH is an increase in left ventricular mass caused by thickening of the left ventricular wall, an increase in left ventricular volume or both. The purpose of this study was to determine the description of diastolic dysfunction in LVH patients using echocardiography at Hasna Medika Hospital Cirebon. The author used a descriptive method on 60 LVH patients as research subjects with the majority of women as many as 40 (67%). The time of the study was carried out in May-June 2021. Based on the results of the study, it was found that concentric LVH was the most common with 56 people (93%), remodeling concentric LVH with 2 people (3%), and eccentric with 2 people (3 %). In subjects with decreased diastolic dysfunction can be seen from the E/A. Of the 60 subjects in this study, 39 people had decreased LV function. There were 39 people with grade 1 diastolic dysfunction, 2 people with grade 2 diastolic dysfunction, and no grade 3 diastolic dysfunction found. The conclusion was that concentric LVH was found in 93% of the total sample, remodeling concentric in 3%, and eccentric in 3%


ABSTRACT The article analyzes mechanical wind-powered water supply systems situated in southern France and northern Germany in the time period between 1880 and 1950, when wind energy was not yet framed as a renewable, but as a rural, decentralized, and manageable solution to generate energy. Using a local approach, I highlight wind energy use in rural areas of Western societies as part of the non-synchronical process of technological modernization that unfolded at the same time as electrification, industrialization, and the implementation of large technological systems. I develop my argument in two steps. First, I provide the micro-historical case studies to examine socio-technological contexts that motivated people to advocate for the use of wind energy in times of electrification and industrialization. Second, I show the connection to general and specific contemporary discourses about wind energy and energy futures in order to provide evidence that the wind projects were part of rural modernization processes.


Total laryngectomy was recommended to be the main surgical method for patients with laryngeal carcinoma for the purpose of radical cure in the past. Recently, partial laryngectomy with larynx reconstruction has been emphasized to preserve phonation and swallowing function, to avoid tracheostoma and to improve the patients ' long-term quality-of-life,with no increase of recurrence rate. The key points to achieve this are selection of proper patients and complete excision of tumors in the surgical procedure. Imaging is important in the pre-operative evaluation of laryngeal carcinoma. It can provide essential information for tumor staging and treatment planning. Moreover, it is of great value in the postoperative follow up process as well as the evaluation of radiotherapy effectiveness.


IgA nephropathy has received growing attention since its recognition 18 years ago. In this review the salient demographic, clinical and pathologic features are summarized. Next follows a discussion of the pathogenesis of the disease in light of current clinical and experimental data, with a proposal for classification based upon immune response, disordered immunoregulation, and the impairment of clearance of immune complexes.


Information are the most valuable commodity in the modern era. In today's lifestyle, society are virtually swarmed with a lot of information that cannot be misplaced or vanished. This study presents a development of web-based lab inventory management system that is used to record, manage and retrieve the lab equipment and components in Fakulti Kejuruteraan Elektrik Kampus Pasir Gudang namely FKEPG-LIMS. The main purpose of this study is to assist faculty members to view and keep track all the available lab equipment that have been purchased. The users can be classified as the Faculty Head, lab technicians, lecturers and students. The database is developed using MySQL and the HTML script written in PHP and Adobe Dreamweaver used design the web interface. The research has successfully demonstrated the feasibility of FKEPG-LIMS in managing and storing all the information. The stored information can also be retrieved, edited and deleted. The developed lab inventory management system will benefits users by providing fast and precise solution in inventory management.


Gasoline desulphurization by pervaporation(PV) membrane process is a newly-emerged desulphurization technology.And this process has the following advantages:low investment and operating cost,depth desulphurization,modular design,easily magnification and construction etc.The technology has attracted the attention of petrochemical field.Membranes selection,module design and industrial application of membrane desulfurization processes are detailed.Finally,some suggestions for further research are presented.


Aspirin is known to be effective in primary and secondary prevention of myocardial infarction. For this purpose aspirin release should be such that It prevents platelet thromboxane (TXA2) generation without Interfering with vascular prostacyclin (PGI2) production. Hence controlled release tablets were prepared to meet the requirements. Both In vitro dissolution and In vivo urinary excretion studies were done to ensure the effectiveness of the formulations. The study proves the usefulness of Carbopol resins for formulating aspirin tablets for minimum risk and maximum therapeutic benefit to the patient.


The Mahafaly plateau region of southwestern Madagascar is traversed by a remarkable swarm of almost 500 parallel dikes following a fracture system, of the same age, extending from the border of the Androy volcanic massif in the southeast to the Karroo formations of the Sakoa region in the northwest. The dikes range from rhyolitic to ultrabasic in composition. Their age can definitely be established as post-Karroo. Although a relationship with the Karroo dolerites of South Africa is suggested, the fissure system seems to be genetically related to the Androy volcanism, in which case the dikes would be upper Cretaceous, whereas the South African Karroo dolerites were related to Rhaetic-upper Liassic volcanism.


REFERENCES 1. Brown S, Patrao F, Verma S, Lean A, Flack S, Polaner D. Barrier system for airway management of COVID-19 patients. Anesth Analg. 2020;131:e34–e35. 2. Lai Y, Chang C. A carton-made protective shield for suspicious/confirmed COVID-19 intubation and extubation during surgery. Anesth Analg. 2020;131:e31–e33. 3. Tsai P. Barrier shields: not just for intubations in today's COVID-19 world? Anesth Analg. 2020;131:e44–e45. 4. Endersby RVW, Ho ECY, Spencer AO, Goldstein DH, Schubert E. Barrier devices for reducing aerosol and droplet transmission in COVID-19 patients: advantages, disadvantages, and alternative solutions. Anesth Analg. 2020;131:e121–e123. 5. El-Boghdadly K, Wong DJN, Owen R, et al. Risks to healthcare workers following tracheal intubation of patients with COVID-19: a prospective international multicentre cohort study. Anaesthesia. 2020 June 9 [Epub ahead of print].


Total per cent excretion of nornicotine in the urine increases with increasing dosage up to a peak of approximately 60 per cent at dose levels of 15 mgm./kgm. and above. The rate of urinary excretion of nornicotine increases with increasing dosage. The rate of detoxication of nornicotine appears to be independent of dosage at the levels studied. Urinary excretion of nornicotine is virtually complete within 16 hours after cessation of administration. The intravenous LD 50 of nornicotine in dogs is 4.0 mgm./kgm.


The essay considers the influence of Christian ethics within the political order. It considers first the witness of Thomas More, then developments in Roman Catholic moral theology since the Second Vatican Council, and finally the dispute over the moral evaluation of the use by AIDS-infected spouses of condoms in order to sterilise their procreative acts. The whole discussion proceeds as a commentary on what Thomas Aquinas says about the temporal promulgation of Eternal Law, and also aims to locate moral argument within the macroscopic context of divine revelation on health and salvation, which the Church must proclaim in its fullness.


This dataset supports the article entitled "Online Concurrent Workload Classification for Multi-core Energy Management" accepted for publication in ACM/IEEE Design Automation and Test in Europe (DATE), 2017.


Disruption of cellular metabolic processes and usurpation of host proteins is a hallmark of herpesvirus lytic infection. Epstein-Barr Virus (EBV) lytic replication is initiated by the immediate-early protein Zta. Zta is a multifunctional DNA binding protein that stimulates viral gene transcription, nucleates a replication complex at the viral origin of lytic replication, and inhibits cell cycle proliferation. To better understand these functions and identify cellular collaborators of Zta, we purified an epitope tagged version of Zta in cells capable of supporting lytic replication. FLAG-tagged Zta was purified from a nuclear fraction using FLAG-antibody immunopurification and peptide elution. Zta-associated proteins were isolated by SDS-PAGE and identified by mass spectrometry (LC/MS/MS). The Zta-associated proteins included members of the HSP70 family and various single stranded DNA and RNA binding proteins. The nuclear replication protein A (RPA 70 and RPA32) subunits and the human mitochondrial single stranded DNA binding protein (mtSSB) were confirmed by Western blotting to be specifically enriched in the FLAG-Zta immunopurified complex. mtSSB co-immunoprecipitated with endogenous Zta during reactivation of EBV positive Burkitt lymphoma and lymphoblastoid cell lines. siRNA depletion of mtSSB reduced Zta induced lytic replication of EBV, but had only a modest effect on transcription activation function. A point mutation in the Zta DNA binding domain (C189S), which is known to reduce lytic cycle replication, eliminated mtSSB association with Zta. The predominantly mitochondrial localization of mtSSB was shifted to partly nuclear in cells expressing Zta. Mitochondrial DNA synthesis and genome copy number were reduced by Zta-induced EBV lytic replication. We conclude that Zta interaction with mtSSB serves the dual function of facilitating viral and blocking mitochondrial DNA replication.


Peritoneal dissemination frequently occurs after surgery in patients with gastric cancer. The presence of peritoneal metastasis after surgery affects prognosis. Very little is known about the biochemical processes involved in the initial attachment of gastric cancer cells to peritoneal mesothelial cells. We conducted in vitro and in vivo studies to assess the role of adhesion molecules and TGF‐β1 in this process, using 4 cell lines derived from human gastric cancers. NUGC‐4 cells, which disseminate early after inoculation into the abdominal cavity of nude mice, predominantly express CD44H and β1 integrin. We found that NUGC‐4 cells adhered to monolayers of mesothelial cells more firmly than to other cell lines. Adhesion of NUGC‐4 cells to mesothelial cells was partially inhibited by antibodies against CD44H or the β1 subunit of integrin and was completely blocked by a combination of these 2 antibodies. Treatment with ligands for CD44H and β1 integrin also inhibited adhesion. In the NUGC‐4 cell culture medium, larger amounts of TGF‐β1 were detected in relation to the increase in cancer cells than in the other cell lines. TGF‐β1 increased the expression of CD44H in NUGC‐4 cells and in mesothelial cells and augmented adhesion and implantation of NUGC‐4 cells to mesothelial cells accompanied by accumulation of extracellular matrix (ECM) components. Treatment with antibodies against both CD44H and β1 integrin inhibited the dissemination of NUGC‐4 cells in the peritoneal cavity of nude mice and prolonged their survival time. Our findings suggest that CD44H and integrins mediate the initial attachment of gastric cancer cells to mesothelial cells and that TGF‐β1 participates in the promotion of the disease. Increased expression of CD44H and of the amount of ligands for CD44H and integrins induced by TGF‐β1 promotes early development of peritoneal dissemination. Int. J. Cancer 70:612–618. © 1997 Wiley‐Liss Inc


Dr.Sun Yat-sen became aware of and attentive to issues of China's farmers,during his endeavor to solve living problems of Chinese.He believed the key to living problems of Chinese was the solution to farmer problems.After the May 4th movement,his views on society and history changed.To benefit the people,serve the people and care the people,those ideas made him realize that it was only by motivating,organizing and relying on farmers to solve problems of their own,that we can solve living problems of Chinese in whole,thereby making the revolution successful.


Objective In order to confirm the value of early diagnosis in the rheumatoid arthritis using high resolution freguency(HFUS) ultrasonography and Doppler ultrasund. Methods Eight hundred limb joints of Rheumatoid arthritis in 40 patients and four hundred limb joints in 20 healthy volunteers were studied. In these joints including wrist, metacarpophalangeal and proximal interphalangeal joints, the ultrasonographic characteristics and blood flows in the joints were checked with HFUS. Both right and left side joints were compared each other in every cases. GE System Logiq-9 unit with computed color-coded Doppler sonography system and 10.0 MHz high frepuency linear-array transducer was applied. Sonographic examination was performed directly or indirectly on the surface of the body. Results The ultrasonic characteristics in rheumatoid arthritis included hydrarthrodial effusion, synovial thickening, and increased vasculature. Hydrarthrodial effusion was found in 578 joints and the positive detected rate was 72.25% (578/800). Synovial thickening was in 498 joints with positive detected rate of 62.25%(498/800). Vascular hypergenesis was found in 140 joints(17.50% 140/800). On power Doppler ultrasonography and color Doppler, mild to marked hyperemia was identified as spot-, rod-, or streak-like signals. Conclusions High-resolution ultrasonography is an easy, safe and effective method for the early diagnosis of synovitis in small joints in rheumatoid arthritis.[JP4]


Communication is an interactive process for building a relationship between the organization and the customer. Effective communication during service encounters has a definite impact on customer's perception of the organization. This qualitative study attempts to explore how the customer's perception of the organization image is impacted by the way the service engineer communicates with the customer during a service interaction and the receptionist's manner of lodging a complaint at the call centre. There has been considerable research on the impact of service quality on consumer perception leading to loyalty towards an organization. However, not much material was found on the impact of verbal and non-verbal communication on service quality. The study was carried out in organizations providing cooling solutions to both individual as well as institutional customers. Telephonic interviews were conducted with both these types of customers. To reinforce the veracity of the conclusions drawn from the first set of interviews, a second round of telephonic interviews were also conducted with customers of two other multinational companies dealing with the same product. An interesting revelation of the study was that most organizations did not revert to the customer for feedback once the complaint was attended to. A follow-up call after the service encounter would certainly enhance the image of the company in the eyes of the customers. It would not only show the organization's commitment to quality but also increase customer loyalty through relationship building.


There are still many students who are still reluctant to study on their own with the reason that they are unable to learn it on their own or are able to perform processing techniques but are unable to understand the process and interpret the output properly. They still need help to be able to master the technique of using software, understand the process, and correctly interpret the output of statistical data processing. The problem-solving method in this service starts from the problems that arise in the field. Moving on from these problems, we took the initiative to provide some kind of training with the aim that the problems that occur can be overcome. The Implementation of Statistical Data Processing Training Activities Using SPSS for STAI Auliaurrasyidin Tembilahan Students Semester VI to Improve the Quality of Student Scientific Work is carried out because these students will face a final project.


The precursor to the foundation of research on Ethiopian languages wasEuropeans* interest in Gecz, the liturgical language of Ethiopia, when they came in contact with ecclesiastical Ethiopians in Rome in the 15th century (Pankhurst 1976: 25). The ecclesiastical Ethiopians were probably those who went to Rome via pilgrimage to the Holy Land. Consequently, publications on Gekez began to come out since early the 16th century. The foundation of Ethiopian Studies particularly that of Ethiopian linguistics was laid in the 17th century by Hiob Ludolf who published dictionaries and grammars of Geez and Amharic with the collaboration he obtained from the learned Ethiopian monk, Abba Gorgorios. In the 19th century, European travellers and missionaries, especially those interested in the languages of Ethiopia, contributed significantly to the study conducted on the languages of the country. The last quarter of the century, the beginning of the modernization of the country and the time of the victory at the battle of Adwa during the reign of Menilek II, witnessed an upsurge of interest in Ethiopia among Europeans. That increase of interest in the county resulted in more publications on its languages (34). It was during this period, in 1894, that Onesimus Nesib, an Ethiopian educated in Sweden, published an Oromo primer (32), perhaps a forerunner of works produced by Ethiopians. He also translated the Bible into Oromo using the orthography he desighed for the language based on the Ethiopie script.


In 2006 in Russian Federation has begun realization of the priority national project of «Health», thus a scientific substantiation of priority directions of the given project hasn't been presented. A research objective the mediko-social analysis of realization of the national project «Health». In the course of research monitoring of work of medical institutions was carried out, sociological questioning is spent. Research has shown that awareness of patients on the priority project "Health" the insufficient. In 45,2% of cases patients couldn't register independently in reception through the Internet, or in clinics the program complex isn't established. The carried out mediko-social analysis of realization of the priority national project «Health» in Kazan has allowed to consider the problem in details awarenesses of the medical personnel and patients, on possibility of rendering of the qualitative mediko-preventive help, and also to carry out organizational sociological analysis activity of employees of medical clinics.


Introduction The effects of common and current environmental stressors on the social behaviour of farm animals are poorly understood and have never before been tested in controlled conditions. Here, we report the results of a longitudinal, multi-factorial experiment designed specifically to examine the individual, additive or interactive effects of elevated ammonia, noise and dim light levels on the social behaviour of growing pigs under strictly controlled environmental conditions. Material and methods Two batches of 126 4-week-old hybrid gilts (50% Pietrain, 25% white Duroc, 12.5% Large White, 12.5% Landrace) were obtained at weaning. Eight rooms were allocated to eight experimental treatments in a 23 multifactorial design. Each treatment comprised elevated or low levels of light intensity (nominally 200 vs. 40 lux), atmospheric ammonia concentration (nominally 20 ppm) and dim light intensities (<40 lux) can affect aggression in pigs. Aggression in pigs is signalled with odour and visual cues. Group-mate recognition can be olfactory, and odour cues may be masked by the ammonia, affecting perception and modulating the formation of stability in the group. The findings reported here may have implications for the welfare of farmed pigs in the UK. Ventilation systems should be designed further to minimise the aerial ammonia concentrations to avoid potential exacerbation of aggressive acts early in the development of the pigs. In addition, it seems that dim lighting may increase aggressive acts, again, early in the development of the pigs, and the industry should take account of this when designing facilities in the future


Recent Box-Jenkins techniques are employed to determine both nonseasonal and seasonal models for actual time series. The applied examples are carefully explained in order to demonstrate the utility of the new procedures that have been developed for use at the identification, estimation, and diagnostic check stages of model development. Even though more methods are now available for model building, it is demonstrated that this fact enhances rather than complicates the model construction phases. Furthermore, for all three applications considered, better models are obtained than it was previously possible to obtain. A new technique is described for optimal forecasting of the original time series when the data have been transformed by a nonlinear transformation.


The 1990s is a period belonging to prose in Contemporary Chinese Literature.Yu Qiuyu writes his prose when he goes out to give lectures.In his horizontal imagination,a new prose style named broad culture comes into being.But,the broad culture is also a restriction forYu Qiuyu's creation,which is difficult for him to break through.


Objective:To investigate the relationship between abnormal chromosome and male dyszoospermia.Methods:Peripheral blood sample from 429 cases patient was collected.Then the chromosomal was analyzed through the culture of peripheral blood lymphocyte and G-dominance band of the chromosome.Results:Totally abnormal chromosome karyotype were 44 cases.The total detection rates of abnormal chromosome was 10.3%.The abnormity rates of azoospermia group,severe oligozoospermia group and oligozoospermia group was 15.8%,6.1% and 4.7% respectively.And the abnormal chromosome karyotype consist of the sex chromose aberration and autosome aberration,the primarily abnormal karyotype was the sex chromosomal numerical aberration.Conclusion:The chromosome karyotype abnormality is one of the most important reasons of dyszoospermia,and severe dyszoospermia usually means higher rate of chromosome aberration.It is necessary for male dyszoospermia to take chromosome examination.


Trauma has a lasting effect on both physical as well as mental well-being of an individual. Traumatic dental injury can be distressing for anyone right from a pre-schooler to a teenager to an adult. Hence it's imperative to restore the affected teeth to reinstate not only the lost confidence but also the lost aesthetics and functionality. This report showcases an intricate case of a 12-year-old male, where uncomplicated crown fracture was associated with extrusive luxation injury in a tooth with open apex which became devitalized and was managed by splinting followed by apexification. Management of even such cases with guarded prognosis can be done conservatively to ensure functional as well as aesthetic rehabilitation. Restoring the tooth to function will help the patient regain his lost confidence. Hence, there cannot be a cookbook approach to manage dental traumatic injuries as many times fractures and luxation injuries occur concurrently.


With the development of collaborative storage services, public cloud has picked up force because of their pay-as-you-go billing structure. For the most part, the information archived on the cloud is secured through encryption before outsourcing which makes it had to recover via searching. The search over encrypted cloud approaches flourish to tackle this issue by utilizing cryptographic and indexing procedures to decide the best outcomes. In any case, the vast majority of these approaches utilize exact matching to fulfil the search criteria. In due course, this exact matching conception was expanded by incorporating similarity ranking algorithms. However, this expansion could not succeed in the practical world due to its dependence on third parties to evaluate the search, thus bargaining the privacy of the stored information. Another drawback is that they require extra computational assets and storage resources for search execution, which sets them far behind from a perfect Search Engine. Hence through this research we implement an advance version of similarity search model by (Pervez et al.; 2016)(Pervez et al.; 2017), known as Contextual Oblivious Similarity based Search (COS2). With the proposed system, authorized users can categorize searches resilient to typing errors. Dissimilar to primitive approaches, COS2 introduces browsing caches to better the client experience. Wordnets and Lexicons with dual encryption mechanisms help realizing relevance searches without revealing confidential data on untrusted cloud domains. Finally, this contextual search thrives to reduce the computational overhead of the overall search procedure.


Temperature-jump experiments of the reaction of the thiocyanate ion with human aquomethaemoglobin have been performed in the presence of a 10-fold excess of inositol hexakisphosphate (inositol-P6). Two kinetic phases corresponding to the α and β subunits were observed. Kinetic parameters of the reaction were evaluated from the reciprocal relaxation times on the basis of a fast relaxation of the iron(iii) ion spin states equilibrium before binding of the ligand. The association, kiL, and dissociation, k–iL, rate constants determined were: kαL= 225 dm3 mol–1 s–1, k–αL= 1.52 s–1, kβL= 2430 dm3 mol–1 s–1, k–βL= 6.51 s–1 at 27 °C, pH 6.44. There was good agreement between the equilibrium constant of the ligand binding step determined by static methods (Kequ= 204 ± 11 dm3 mol–1) and that evaluated from kinetic data [(KαLKβL)1/2= 235 ± 12 dm3 mol–1]. The value kβL/kαL= 11 obtained ensured proper separation of the two kinetic phases. Analyses of the subunit relaxation amplitudes, δEiL, showed that inositol-P6 perturbed the absorption spectrum of the β subunits. This suggests that in the presence of the organic phosphate, methaemoglobin behaves as a protein with independent binding sites rather than as an allosteric molecule. The kinetic and relaxation amplitude spectral characteristics of the subunits, in the presence of inositol-P6 have demonstrated that the kinetic dynamics are effectively decoupled in a stable tetramer.


The role of gonadotropins (LH and FSH) and steroid hormones [testosterone (Te) and 17β-estradiol (E2)] in the development of ovarian steroidogenic capability and responsiveness to gonadotropins was studied in ovaries from 4-day-old rats maintained for 8–12 days in culture. Ovaries cultured in medium without hormonal supplementation produced small and decreasing amounts of steroids [progesterone (P) and E2] during culture in spite of continued morphological development. The addition of LH (1 or 10 μg/ml) did not enhance P production during the first 4 days of culture but significantly stimulated it during days 4–8 of culture. FSH (0.5 μg/ml), Te (1 μg/ml), and E2 (1 μg/ml) had no effect on their own, but when FSH or Te was added together with LH, P production during days 4–10 of culture was greatly enhanced. The acquisition of ovarian responsiveness to LH, as expressed by increased P production in response to the hormone, was achieved after 4–8 days of culture even without supplementation of the medium wit...


The crystal structures of aqua(2,2′-bipyrimidine-N,N')(4,5-dihydroxy-1,2-benzoquinonato-O,O')copper(II) pentahydrate, [Cu(C6H2O4)(C8H6N4)(H2O)].5H2O, containing five-coordinated copper(II) with slightly distorted square-pyramidal geometry and of bis(4,4′- dimethyl-2,2′-bipyridine-N,N')(4,5-dihydroxy-1,2-benzoquinonato-O,O')nickel(II) monohydrate, [Ni(C6H2O4)(C12H12N2)2].H2O, comprising six-coordinate nickel(II) with distorted octahedral geometry, are reported. In both complexes, the dianion of 2,5-dihydroxy-1,4-benzoquinone occurs in the bidentate o-benzoquinone form which chelates through the 1, 2 O atoms.


The effect of non-uniform basic concentration gradient on the onset of double diffusive convection in a micropolar fluid layer heated and saluted from below and cooled from above has been studied. The linear stability analysis is performed. The eigen value of the problem is obtained using Galerkian method. The eigen values are obtained for 1) free-free 2) rigid-free 3) rigid-rigid velocity boundary combination with isothermal temperature condition on spin-vanishing permeable boundaries. The influence of various micropolar parameters on the onset of convection has been analyzed. One linear and five non linear concentration profiles are considered and their comparative influence on onset is discussed and results are depicted graphically. It is observed that fluid layer with suspended particles heated and soluted from below is more stable compare to the classical fluid without suspended particles.


"Since there appear to be so many Americans willing to study American politics, what necessity is there for foreigners to do the same?" (Polsby 1972: 499).