The authors analyzed the manifestations of anxiety and depressive disorders, disturbance of autonomic regulation and changes in the level of catecholamines in the blood of patients with acute coronary syndrome from the perspective of outcomes of the disease. 102 men with a diagnosis of acute coronary syndrome were examined. Blood samples for the determination of catecholamines (epinephrine, norepinephrine, dopamine) was performed at admission, psychological examination and scrutiny of heart rate variability was performed on the third-fourth day of the hospitalization. All patients were divided into three groups. The first group was executed on 14 (13,7%) patients who had fatal myocardial infarction developed during hospitalization. In the second group there were 40 (47,1%) patients with non-fatal myocardial infarction. The third group included 48 (47,1%) patients with unstable angina. It was shown, that levels of anxiety and depression were inverse correlated with the concentration of dopamine in the plasma, and adrenaline levels are positively correlated with indicators of overall heart rate variability and its high frequency component. Thus, in patients with acute coronary syndrome, who developed myocardial infarction the incidence and severity of anxiety and depressive disorders is substantially lower than in patients with unstable angina. Increase in high frequency component of heart rate variability was more typical for patients with acute coronary syndrome who developed fatal myocardial infarction during hospitalization. High levels of dopamine in the blood plasma are typical for patients with nonfatal myocardial infarction.


............................................................................................................... vi CHAPTER 1: INTRODUCTION .................................................................................. 1 1.1 HIV/AIDS ....................................................................................................... 1 1.2. HIV/AIDS effects on the auditory system ..................................................... 1 1.3. Smartphone automated hearing health technology ...................................... 4 1.4. Rationale ...................................................................................................... 6 CHAPTER 2: METHODOLOGY ................................................................................. 8 2.1 Research aim.................................................................................................... 8 2.2 Research design ............................................................................................... 8 2.3 Ethical considerations ....................................................................................... 8 2.4 Participants ....................................................................................................... 9 2.5 Test environment and testing personnel ......................................................... 10 2.6 Equipment ...................................................................................................... 10 2.7 Procedures ..................................................................................................... 12 2.7.1 Otoscopy .................................................................................................. 12 2.7.2 Tympanometry ......................................................................................... 12 2.7.3 hearTestTM smartphone application ......................................................... 13 2.7.4 SA Eng DIN smartphone application ........................................................ 15 2.7.5 Manual Diagnostic Audiometry ................................................................. 16 2.8 Data analysis .................................................................................................. 17 CHAPTER 3: RESEARCH ARTICLE ....................................................................... 18 Monitoring hearing in an infectious disease clinic with mHealth technologies ...... 18


We investigated whether preoperative neoadjuvant chemotherapy is associated with increased surgical site infection (SSI) rate in patients with locally advanced oral cancer.


Introduction: In the CLL11 study, obinutuzumab (G) plus chlorambucil (Clb; G-Clb) significantly improved outcomes relative to rituximab plus Clb and Clb alone in previously untreated patients (pts) with chronic lymphocytic leukemia (CLL) and comorbidities, but was associated with an increased incidence and severity of infusion-related reactions (IRRs), cytopenias and treatment discontinuations (Goede et al. N Engl J Med 2014; Goede et al. EHA 2018). IRRs have been associated with the release of pro-inflammatory cytokines, including interleukin-6 (IL-6; Freeman et al. Blood 2015). Tocilizumab (TCZ) is a monoclonal antibody that blocks downstream signaling by IL-6. It has regulatory approval (FDA/EMA) for the treatment of chimeric antigen receptor T-cell induced cytokine release syndrome, and could potentially be used to limit the IRRs associated with G administration. GALACTA was a randomized, double-blind, Phase Ib trial in previously untreated pts with CLL and co-morbidities (NCT02336048). Its primary objective was to determine the safety and tolerability of TCZ prior to G-Clb. Secondary endpoints included pharmacokinetics and pharmacodynamics of TCZ in this population, and impact on the efficacy of the G-CIb combination.
 Methods: Previously untreated CLL pts who were unsuitable for more intensive therapy (CIRS score >6 or creatinine clearance <70mL/min) were randomized 2:1 to receive a single IV infusion of TCZ 8mg/kg or placebo (PLB) prior to G on day (D) 1 of cycle (C) 1 of G-Clb. Pts were stratified prior to randomization by absolute lymphocyte count (ALC; >50x109/L) and mean fluorescence intensity of CD20 on CLL-gated cells. G-CIb was administered as: G 1000mg IV on D1/D2 (100mg/900mg), D8 and D15 of C1, and D1 of C2-6; Clb 0.5mg/kg PO on D1 and D15 of C1-6. Prior to the first G dose in C1, standard premedication (antipyretic, antihistamine, corticosteroids) was administered in addition to TCZ or PLB. IRR was defined as any adverse event (AE) occurring during or within 24 hours of G infusion and judged by the investigator as related to G.
 Results: A total of 38 pts were enrolled between June 26, 2015 and Jan 22, 2018; 25 were randomized to TCZ and 13 to PLB. Median age was 74 years (range 54-87), 63% were male, 95% had ECOG PS 0-1, and 95% had Binet stage B/C disease. Baseline characteristics were well balanced, with the exception of more males in the TCZ arm (72%) than the PLB arm (46%). Despite a similar proportion of baseline ALC ≤50 versus >50x109/L in the two treatment arms, more pts in the TCZ arm had levels which were >100x109/L (15% in PLB vs 28% in TCZ). At the time of analysis, 25 pts had completed all 6 cycles, 6 remained on treatment, and 7 had discontinued.
 IRRs occurred in 18/25 (72%) pts in the TCZ arm and 10/13 (77%) in the PLB arm. Grade ≥3 IRRs occurred in 11/25 (44%) pts in the TCZ arm and 4/13 (31%) pts in the PLB arm. Four pts discontinued treatment due to IRRs: 3 (12%) in the TCZ arm and 1 (8%) in the PLB arm. Similar to previous reports, cytokine levels peaked on D1 after 100mg G had been administered. Serum amyloid A (Figure 1) and C-reactive protein (CRP) (Figure 2) were sub-optimally reduced in the TCZ arm. Of the 19 pts with measurable TCZ levels, no marked differences in exposure were seen based on IRR intensity. However, TCZ exposure was lower on average than in rheumatoid arthritis pts of equivalent weight treated with the same dose (mean Cmax 154 vs 193µg/mL), and TCZ-treated pts that developed IRRs had comparatively less suppression of CRP than those who did not.
 Conclusions: Preliminary results suggest that use of a single 8mg/kg dose of TCZ prior to the first dose of G was feasible, but did not appear to prevent IRRs in this pt population. The study was primarily designed to assess the safety of the combination, and was underpowered to detect meaningful differences between groups in IRR severity. TCZ-treated pts who developed IRRs had higher baseline risk than those who did not, and the TCZ dose may have been insufficient, resulting in the lack of efficacy. Whether inhibition of this pro-survival cytokine enhances the cytotoxic potential of the regimen is not yet determined; updated results will be presented at the meeting.

 Freeman: Seattle Genetics: Honoraria; Abbvie: Honoraria. Böttcher:Celgene: Research Funding; Genentech: Research Funding; AbbVie: Honoraria, Research Funding; Janssen: Honoraria; Roche: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding. De la Serna:Roche: Consultancy, Membership on an entity's Board of Directors or advisory committees; AbbVie: Consultancy, Membership on an entity's Board of Directors or advisory committees; Gilead: Consultancy, Membership on an entity's Board of Directors or advisory committees; Janssen: Consultancy, Membership on an entity's Board of Directors or advisory committees; Novartis: Consultancy, Membership on an entity's Board of Directors or advisory committees. Gobbi:Novartis: Consultancy; Celgene: Membership on an entity's Board of Directors or advisory committees; Ariad: Membership on an entity's Board of Directors or advisory committees; Amgen: Consultancy; Janssen: Consultancy; Pfister: Membership on an entity's Board of Directors or advisory committees. Di Bernardo:Roche: Employment. Mallalieu:Roche: Employment, Equity Ownership. Nielsen:F. Hoffmann-La Roche Ltd: Employment, Other: Ownership interests PLC. Knapp:Roche: Employment. Gribben:Janssen: Honoraria, Research Funding; Abbvie: Honoraria; Acerta Pharma: Honoraria, Research Funding; TG Therapeutics: Honoraria; Celgene: Consultancy, Honoraria, Research Funding; Medical Research Council: Research Funding; Novartis: Honoraria; Kite: Honoraria; Cancer Research UK: Research Funding; Pharmacyclics: Honoraria; Unum: Equity Ownership; Roche: Honoraria; Wellcome Trust: Research Funding; NIH: Research Funding.


The invention discloses a method for producing a Nixing pottery by stacking and carving. The method comprises the steps of preparing a blank material, forming a blank body, finishing the blank body, decorating the blank body, drying the blank body and firing the blank body, wherein the step of decorating the blank body comprises the sub-steps of moisturizing the blank body, preparing a stacking and carving material, stacking and carving; and the step of firing the blank body comprises the following sub-steps of: 1) placing a dry blank body into a kiln, gradually heating at a speed of 20-30 DEG C per hour, when heating to be 80-120 DEG C, stopping heating, and keeping for 20-28 h; 2) gradually heating again at a speed of 20-30 DEG C per hour, when heating to be 350-500 DEG C, stopping heating, and keeping for 0.5-2 h; 3) gradually heating again at a speed of 20-30 DEG C per hour, when heating to be 550-700 DEG C, stopping heating, and keeping for 0.5-2 h; 4) gradually heating again at a speed of 30-60 DEG C per hour, and heating to be 1060-1100 DEG C; and 5) naturally cooling.


The paper was intended to make a tentative point about the organizational reform and types of organization, i.e., international, national and private. The author explores in the basics of public administration and contextualizes the variables often employed critically for the discipline of public policy and administration. They would include, for instance, the democratic principles, importance of communication and negotiation, the concept of policy network, diversity, technology and ethics, which are applied and argued over the transition from 1947 GATT to a WTO inauguration in 1995. The present study of organizations or their reform would massively be consulted for the national or private reform, which tends to shed a focus on the legal perspective, organizational efficiency and reform. The studies in variance with the types of organization or institutional agenda, as well as in the viewpoint of public policy and administration are generally lacking or insufficient, at least, less systemic or fragmented. While the WTO has made much accomplishment since its inception, it would equally be true that the criticism and new vision had been raised and will be likely ahead. As it is one of the most dynamic and active international organizations, the author likes to exemplify it to test a scope of policy variables as interactive with the last and extended renovation in 1987-1994, which continue to be relevant with the new agendas and vision for a better paradigm of WTO and as an international organization. The author also expects that the future research can develop a set of distinct elements in response with the types of organization and from the viewpoint of public administration.


This paper describes a synchronization acquisition algorithm for ultra-wideband impulse radio (UWB-IR) designed for energy constrained applications, such as sensors networks. The receiver performs an energy detection relying on a timebase-thresholder which is able to timestamp the threshold crossings. The algorithm exploits a synchronization preamble composed of time-hopped unmodulated symbols and manages to retrieve the time hopping sequence used by the transmitter. Simulations have been performed to validate the performances of such an algorithm in terms of accuracy and mean elapsed time in acquisition. The simulations results demonstrate the algorithm's validity and its applicability to systems with severe energy constraints.


Pedestrians are the basic nucleus that uses the road, but interest in them did not emerge as a major indicator in the planning and design processes, and the study gave high focus on pedestrian behavior and how they deal with their crossings as the most important equipment that provides a safe and comfortable environment for pedestrian traffic, and the efficiency of the crossings And its importance in preventing pedestrian traffic from interfering with vehicle traffic and the extent of its respect for the behavioral aspect of the planning process. Al-Haram Street suffers from traffic problems with regard to pedestrian crossings, so cases have been studied inside Al-Haram Street that express the different types of crossings, and observation and monitoring has been relied on through field visits, photography and aerial maps. The results indicated that one of the most important reasons for non-compliance with some Pedestrians in the roads of their own lanes is the lack of infrastructure necessary to provide safe points for dispersed crossing, lack of traffic culture, failure of the designer to take into account the behavioral aspect of pedestrians, in addition to the absence of deterrent laws for violators.


In the presence of the pandemic caused by covid-19, digital platforms were implemented to continue with the education processes from isolation. In the case of higher education that imparts various areas of knowledge, different results were identified in the use of the same digital platforms. In response to this, it was necessary to analyze how the technological characteristics implemented at a higher level in Mexico have influenced the participation, attendance and evaluation of students by area of knowledge. Therefore, a data envelopment analysis was performed to measure the efficiency of the inputs and outputs described by the literature; the limitations of the research was circumscribed by the amount of data to be analyzed. As a result, it was identified that the greater the number of features added to the digital platforms, the better levels of participation, attendance and evaluation of students by academic area. Likewise, when considering future lines of research, it is considered ideal to elaborate on the various methods of digital evaluation, such as the digital portfolio and feedback.


and Thesis Organization The thesis is enclosed in the research area of reconfigurable computing which, in the last years, has experienced a remarkable growth as a result of the impressive evolution of reconfigurable devices. In this area, Field Programmable Gate Arrays (FPGAs) are the most outstanding representative from the commercial point of view. Traditionally FPGAs have been used for prototyping, in previous to the final Application Specific Integrated Circuit (ASIC) design stages. However, the interest in the integration of FPGAs in final products has been growing in the last years. FPGAs are preferred for small production volumes, where the ASIC masks high cost is unaffordable and also in products where time-to-market is a priority, and waiting for a complete ASIC design cycle is not desirable. State of the art FPGAs are highly integrated electronic circuits, composed of tens of millions of system gates, with competitive speed, performance and configurability. These devices have evolved from simple gate arrays to complex platforms that include embedded memory, multipliers and even microprocessors and digital signal processing elements. Additionally, the fine grain nature of the reconfigurable arrays, make FPGAs suitable for a broad set of application domains. On the other side, and mostly in the academic community, there are custom reconfigurable devices with different granularity levels that permit to achieve higher performance, compared to commercial FPGAs, but for a certain application domain. Although there are very good solutions in the academic state of the art, their main drawback from the industry point of view is that they require specific design environments and also, that the efforts and resources needed for designing such solutions are very high. This thesis work is focused on providing solutions that target commercial fine grain reconfigurable devices, FPGAs, in order to take advantage of existing tools and to keep the proposed solutions closer to the industry. Today FPGAs provide different reconfiguration options. Among them, the most challenging one is partial reconfiguration. This feature has special interest, as it permits system updates on the fly once the device is deployed, without the need of stopping it and without theoretical loss of performance. Partial reconfiguration is also an attractive feature because it permits to allocate different tasks/cores running in parallel in the device and change them on the fly as needed without disturbing other tasks/cores. This basic idea, brings software-like flexibility to hardware which, in combination with its inherited parallelism, opens the door for a broad amount of possibilities and applications, like runtime adaptive super-computing, adaptive embedded software


Formaldehyde is a very reactive compound capable of interacting with many functional groups of proteins including intermolecular and intramolecular cross-links of the molecules. The formation of cross-linking bonds may induce conformational change in proteins that favor further interaction of functional and hydrophobic groups.
Formaldehyde which has been using illegally as a chemical preservative by some fish traders in our country. A study was carried out to determine the effects of irradiation
(1.5 KGy) on formaldehyde concentration and nutritional (protein and lipid) changes of formalin (37% formaldehyde) treated fish (fresh) samples and found that the
concentration of formaldehyde both in treated samples (0.37% formalin and 0.37% formalin with 1.5 KGy irradiation) were 37.0 µg/gm and 36.75 µg/gm. On the other
hand, the amount of protein and lipid in treated samples before radiation (14.56% and 3.49%) and after radiation (14.15% and 3.25%). That means, radiation has no effect on the change of protein, lipid and formaldehyde.


Purpose
A minimum dropout age (MDA) requires potential dropouts to stay in school until graduation. Most countries have an MDA at least 16. An MDA greater than 16 requires potential dropouts to stay in school for at least one more year, which immediately reduces their available time and opportunities to commit a crime in the community. This study aims to examine how a higher MDA reduces crime in the community. The authors then show a higher MDA helps potential dropouts to become an entrepreneur.

Design/methodology/approach
The authors develop an economic model of crime that shows how an MDA greater than 16 affects contemporaneous juvenile crime in the community. Considering an MDA of 16 as a benchmark MDA, a hypothetical example with simulated data on the USA is used. The authors then show how a higher MDA offers a financial opportunity for the professional development programs.

Findings
An MDA greater than 16 reduces crime in the community. Reducing crime allows preventing social and monetary cost on juvenile delinquency. This economic efficiency offers a financial ability for adolescent training and other development programs and thereby reduces unemployment and other adverse consequences of the society.

Originality/value
Unlike previous studies, the authors develop an economic model of crime that shows a hypothetical relationship between an MDA and contemporaneous juvenile crime in the community. A higher MDA allows more financial ability for juvenile development programs in high school to improve the entrepreneurial skills.


Now a days life is so fast, noone have enough time to maintain their body as they wish.Because of fastfood, abnormal life, stress the cardiac disease are rised. In last decade the number of people are increased which are affected from cardiac problem. The allopathic medicines gives fast action but they produce side effects also and they are very costly. So the use of herbal plants is convenient option. Herbal plants are a better option of allopathic medicines and by regular use of herbal plants not only you can cure disease but you also feel a new positive energey.


1. 0.05—0. 1 ml of 25 % human serum albumin. 2. 0.01—0.5ml of 1 N HC1. 3. 3—5ml of TcO4 in 0.9% saline. 4. 1 N HC1 and 1 N NaOH to adjust pH to 7—8. We have refined the zirconium crucible (Onemet Co., Albany, Ore.) electrolysis equipment of Ben jamin by isolating the platinum electrode to prevent hydrogen production and subsequent reduction of technetium. The product analysis was performed on a 0.9 X 35-cm gel chromatography column (Sephadex G25) eluted with N2 purged saline. The percentage ad sorbed to the column represents the hydrolyzed un chelated fraction of technetium. A standard was counted to assure activity balance of @@mTc.


The quality factors of quantum bit (qubit) rotations in single self-assembled quantum dots were investigated using photoluminescence spectroscopy. Rotations with azimuthal angle ϕ along the equator of the qubit sphere were implemented by varying the time delay between two π∕2 pulses, resulting in a "free rotation" quality factor Q0=9.8×104. Qubit rotations with polar angle θ as large as 10π along the meridian of the qubit sphere (Rabi oscillations with zero detuning) were realized with a quality factor QR∼18, in experiments probing an excited excitonic state.


This report explores the best ways of providing simple metrics to measure success in meeting the preference of more people to be cared for and die in a home setting, thus
reducing the number of patients dying in acute hospitals.


Biopharmaceuticals are medicines whose active drug substance is made by living cells. Copies of these drugs, called Biosimilars are not identical to their reference drug and therefore specific regulatory requirements for registration apply. Whereas pharmaceutical quality evaluation requires a full dossier and a detailed comparative analysis to the reference drug, non-clinical and clinical requirements are much less extensive compared to the requirements for an innovator. Limited clinical experience and their complex nature exclude biosimilars from being considered interchangeable with the reference drug. The utilization of trastuzumab biosimilar medications is of particular interest in HER2-positive breast cancer as these drugs have the potential for cost savings and increased utilization/access to HER2 targeted therapy in both early stage and metastatic HER2-positive breast cancers. Five trastuzumab biosimilars: MYL-1401O (Ogivri), CT-P6 (Herzuma), SB3 (Ontruzant), PF-05280014 (Trazimera), and ABP980 (Kanjinti), have now been approved by the US Food and Drug Administration (FDA) for use in HER2-positive breast cancers. This review provides an overview of these agents with special consideration of the development and approval process, including available clinical data results for these trastuzumab biosimilars.


Global energy security relies on fossil-based resources that are affiliated with the source of global warming, apart from punches of political and economic instabilities. Biomass is a promising alternative carbonaceous feedstock used for the production of clean energy that could have the potential to substitute for fossil fuels. This study aims to present a conceptual design that considers the criteria to identify the upper theoretical limits of biomass conversion, thus providing the potential approach to the conversion of three biomass (by-products: dry molasses, dry bagasse, and dry filter cake) through gasification, in order to contribute the biomass carbon-capturing by the model assessment of stoichiometric mass conversion and energy efficiency indicators into simple thermodynamic energy vectors, such as alcohols, alkanes, and syngas (a mixture of carbon monoxide and hydrogen). Modeling plays up the importance of stoichiometric efficiency of biomass conversion with the supply of oxygen and hydrogen. This realizes that the multi-product diversification of feedstock into syngas, hydrocarbons, and alcohol through integrated process schemes could have the potential to fill the energy gap and help to manage environmental load. In regard to biomass conversion results, the mass conversion and energy conversion efficiencies of dry bagasse have better conversion potential than molasses and F. cake (% mass conversion = 129 in syngas, 54.4 in alkane, and 43.4 in alcohol; % energy conversion = 94.3 in syngas and 93.3 in alkane and alcohol).


This study is the result of an extension activity performed with legal guardians of adolescent users of the services offered by Specialized Reference for Social Assistance (CREAS I) at Campina Grande. The main objective was to provide a space for those guardians to facilitate the reframing of the facts occurred, based on the theoretical assumptions of Logotherapy and work in support groups. About 20 adults, male and female, over 18 years old attended this activity. The interventions were divided into 6 biweekly meetings that occurred during the 2nd semester of 2013. The results point to the importance exerted by the support group in facilitating the process of reframing the situation of suffering, resulting from violation of rights experienced by female adolescent users of CREAS.


: For coal gangue sorting task, most of them are still in the traditional gangue sorting method, for this situation, based on the analysis and summary of previous research work, a coal For coal gangue sorting task, most of them are still in the traditional gangue sorting method, for this situation, based on the analysis and summary of previous research work, a coal gangue identification method based on improved YOLOv5s is proposed. On the basis of the original network model to make improvements in the backbone module to add non-local attention mechanism for multi-scale network prediction of gangue, improve the feature extraction ability of the model; and design adaptive anchor frame to predict gangue location information efficiently; improve the loss function of the original model to reduce the target miss detection, so as to effectively improve the accuracy of gangue identification. Finally, through experimental comparison, compared with the original network, the improved YOLOv5s model has an mAP value of 8.7%, and the detection speed has been greatly improved.


Production of dry breakfast food characterized with tender, crispy; foamy structure, as well as the production of semi products for their production is more applied in Russia and other countries. Basic raw material for production for production of semi products and expanded cracker type breakfast food are plant materials with high starch content. Raw material compositions and temperature regimes for production of crackers on potato starch grinded rye wheat bread basis enriched with wheat germ flakes with shares of 25, i.e. 10% and corn gluten with share of 20% were developed with the aim to increase nutritive value of extruded crackers. .


Two simple, accurate and precise UV-Spectrophotometric methods have been developed and validated for the estimation of Prulifloxacin in pharmaceutical tablet. Method I was based on Spectrophotometric measurement of Prulifloxacin at absorption maxima at 272.4 nm and Method II area under curve was applied for analysis of Prulifloxacin in the wavelength range 264.0 to 277.2 nm. The drug was found to obey Beer's -Lambert's law obeyed in the concentration range of 5–25 μg/mL and the correlation coefficients were found to be 0.999 for both methods. The Percent estimation of the drug was found nearly 100% for both the methods. The percent recoveries were found to be 100.37% for method I and 100.64% for method II representing accuracy of the methods. Validation of the proposed methods was carried out for its accuracy, precision, linearity, ruggedness according to ICH guidelines. The limit of detection was found to be 0.8 for both the methods and the limit of quantitation was found to be 2.4 for method I and 2.42 for method II. The developed methods were also compared statistically using unpaired t-test by Welch Correction. The proposed methods can be successfully applied in routine work for the determination of Prulifloxacin in bulk and pharmaceutical tablet dosage form.


Difficulties with emotion regulation are commonly experienced by people with learning disabilities (LDs). This paper provides an overview and evaluation of an eight-week group aimed at teaching skills to support eight adults with LDs to effectively manage their feelings. The group was based on Dialectical Behaviour Therapy (DBT) principles and was adapted in order to take account of the needs of people with LDs. After attending the group, clients reported lower levels of psychological distress, and reported making progress towards achieving their goals of managing feelings more effectively. Feedback from clients and carers indicated that the group had been a valuable and enjoyable intervention. We conclude that relatively short-term, group-based interventions based on DBT principles may be a valuable resource to offer to adults with LDs who are struggling to manage their emotions.


Lloyd Arthur Thompson (1932-97), one of the most respected classicists on the African subcontinent, devoted forty years of his life to the cause of classics in sub-Saharan Africa. The major events of his career and a list of his most important publications bear testimony to the immense influence he has had on scholarship both within and outside Africa.


John von Neumann (1903–1957) was an interdisciplinary thinker who not only brought fresh approaches to seemingly disparate fields, but discovered and developed their interrelationships. His greatest achievement in cognitive science was his contribution to the concept of the stored-program computer, where he applied the logical correspondence between nervous systems and computing systems to the logical design of electronic computers.

Keywords:

programmable electronic computers;
theory of games;
self-reproducing cellular automaton;
logic of neural nets


Provided are coal briquettes having superior heat strength and a method for manufacturing same. The method for manufacturing the coal briquettes comprises the steps of: i) providing powdered coal; ii) providing graphite for restraining the degradation of the coal briquettes at a high temperature; iii) providing a curing agent and a binder; iv) mixing the powdered coal, graphite, curing agent and binder so as to provide a mixture; and v) forming the mixture so as to provide a coal briquette. In the step of providing the mixture, the ratio of the amount of graphite to the total amount of the powdered coal and the graphite is greater than 0 and less than or equal to 0.3.


PurposeThis paper studied the effects of music plus fragrance or music alone on consumer purchase behaviour, footfalls and repeat visits to retail stores in the context of the mall.Design/methodology/approachA primary research was conducted through a structured questionnaire. A field study was conducted in two malls that attract the maximum crowd. The data from 250 respondents were analysed in total.FindingsAs per the present study, the combination of playing music with fragrance is more effective compared to playing music or fragrance alone on shopping behaviour, footfalls and repeat visits in retail stores in emerging markets like India.Research limitations/implicationsThe study is more confined to a comparative study of the effectiveness of music with or without fragrance on consumer purchase behaviour and footfalls in retail stores located in malls. In view of research design, this could be a limitation of the study as types of music and other ambiance factors are not considered. The present study can be extended to religion as the religiosity of respondents may give a different response. The urban respondents may vary when compared to rural consumers. Therefore, the study can be extended by adding the rural or A-city mall or smaller malls in big cities. Research can be extended in the coronavirus disease 2019 (COVID-19) era to see if there is a change in consumer behaviour. It can also be extended to consumer's preference for different music and different fragrances.Practical implicationsThis paper provides marketing managers and retail owners with valuable insights on the importance of using music with fragrance in retail stores to create unique consumer experiences in emerging markets that are different from developed countries. Managers should try to create both music, and fragrance in the store to improve purchase intention, and stay longer. To ensure that the planned music and fragrance approach creates the ambiance for consumers, marketing managers are advised to conduct market research. Special care should be taken for younger visitors to the store by creating the right ambiance. The present research will help many offline retailers' managers to strive for new competitive advantages through creating favourable shopping environments by understanding cultural differences.Originality/valueThe research gives direction to use music with a fragrance in the retail ambiance in the malls which will lead to improved consumer purchase, more footfalls, repeat visits and staying longer in emerging markets like India, which is a destination for global brands. Integration of three models of impulse buying (Rook and Fisher, 1995), individualism and collectivism (Triandis, 1995) and stimulus–organism–response (S–O–R) model of Mehrabian and Russell (1974) is used to explain the complex behaviour of consumers towards more purchases and repeat visits. The study will shed light on the quandary that retailers in the organised sector face in emerging markets such as India regarding the use of music and fragrance, as well as the impact on purchase behaviour, footfalls and repeat visits.


This paper deals with the security voting structure in an auction mechanism used to sell an item of high-tech. The design of security voting structure allows the seller to choose between two objectives that are not mutually consistent. The security voting structure design trades off between sell all the shares and retain some shares to benefit from the future dividends generated by the winner. However, if the seller wants to maximize his revenue, he should retain some shares to benefit from the future dividends generated by the acquirer. On the other hand, if he wants to sell his high-tech to the most efficient candidate, he should sell all the shares.


Socratic seminars have been practiced by educators as a supplement to classroom teaching. However, how the effects are achieved has not been thoroughly investigated. This study is an analysis of seminars conducted over three years with children five to sixteen years old. The students' group interaction was analyzed closely through a phenomenological approach. The analysis focused on how the seminar culture was taught and learned and shows that the skilled participants shifted their interaction towards an "inquiring" dialogue, and that the rhetorical power changed to a more cooperative communication. The students' learning proceeded through stages, partly different from the anticipated ideal. The facilitator's ability to handle rule breaking, and to create a safe environment for intellectual exploration, was significant. The findings show that "silent" moves like gestures and glances helped maintain a productive and egalitarian culture. The participants developed their thinking skills over time, evolving from relativism to critical examination.


A semi-analytical formulation is presented in this paper for the probability computation of branch current in multiphase systems. The developed formula is derived based on the linear power flow model in rectangular coordinates. The system uncertainty injections can be renewable energy resources or loads and are modeled using a Gaussian mixture model (GMM). The developed formula can be used to compute the line current violation probability as well as integrate into optimal power flow problem as chance-constraint relaxation. The proposed formula is first compared with the Matlab embedded numerical integration function to show its performance. Besides, the semi-analytical formula is validated and compared with the Monte Carlo simulation method using the IEEE 123-bus system, EPRI Ckt5, and Ckt7 systems.


A recent estimate of wounded from the Afghanistan war is close to 17,000 and from the Iraq war over 30,000. Extremity trauma is the one of the hallmark injuries from these conflicts. The long-term effects of this number of extremity-injured patients on our military and civilian health care systems is unknown. The relative severity, if amputation rate can be used as a surrogate, is significantly higher than in civilian trauma. In this article, we discuss the most current management strategies used in these complex patients and the myriad of lower extremity disease they experience. We also discuss a new "standard" for patients with severe lower extremity trauma. Previous expectations were to return patients to their preinjury level of function with limb retention. Now, the new expectation of this group of patients is to recover in a time frame and function level equivalent to a below knee amputee, which is a more accelerated course. Several advances have been made in an effort to offer similar functional results to these severely injured patients to include the gradual expansion muscle (GEM) flap, which corrects soft-tissue defects as well skeletal defects without the use of free-tissue transfer. Another significant advance is the Intrepid Dynamic Exoskeleton Orthosis (IDEO), which is a plantarflexion powered carbon fiber ankle-foot orthosis that allows patients with limb salvage the opportunity to return to high-impact activities. Other germane topics reviewed include management of calcaneal fractures with severe soft-tissue injury, partial foot amputations, and elective amputations for the indication of pain.


We have mapped the dust continuum emission from the molecular cloud covering a region of 28 pc × 94 pc associated with the well-known H  region RCW 106 at 1.2 mm using SIMBA on SEST. The observations, having an HPBW of 24 �� (0.4 pc), reveal 95 clumps, of which about 50% have MSX associations and only 20% have IRAS associations. Owing to their higher sensitivity to colder dust and higher angular resolution the present observations identify new emission features and also show that most of the IRAS sources in this region consist of multiple dust emission peaks. The detected millimeter sources (MMS) include on one end the exotic MMS5 (associated with IRAS 16183-4958, one of the brightest infrared sources in our Galaxy) and the bright (and presumably cold) source MMS54, with no IRAS or MSX associations on the other end. Around 10% of the sources are associated with signposts of high mass star formation activity. Assuming a uniform dust temperature of 20 K we estimate the total mass of the GMC associated with RCW 106 to be ∼10 5 M� . The constituent millimeter clumps cover a range of masses and radii between 40 to 10 4 Mand 0.3 to 1.9 pc. Densities of the clumps range between (0.5-6) ×10 4 cm −3 . We have decomposed the continuum emission into Gaussian and arbitrary shaped clumps using the two independent structure analysis tools gaussclumps and clumpfind respectively. The clump mass spectrum was found to have an index α of 1.6 ± 0.3, independent of the decomposition algorithm used. The index of the mass spectrum for the mass and length scales covered here are consistent with results derived from large scale CO observations.


The movement for the Restoration of Democracy (MRD) was launched against the then military dictatorship in Pakistan in the 1980s. This paper is an attempt to present a historical sketch of the movement and also to discuss the role of the Left in that movement. The study considers those political parties as 'Left' which were following Socialist/Communist ideology, based in Sindh, province of Pakistan, specifically Awami Tehrik, a Marxist-Leninist-Moist party, and the Communist Party of Pakistan. This research is based on relevant literature, especially jail diaries and conducting interviews with victims of Communist Case registered by then military regime against communist leaders. The research addresses the events and mass movements launched by the Left in order to strengthen the movement for the restoration of democracy. Moreover, this paper shows how the Left converted a movement for the restoration of democracy into a great mass movement against the then military dictatorship. Key Words: Communist case, democracy, left, military dictatorship, movement for restoration of democracy, Pakistan, Sindh.


Background: This meta-analysis aimed to explore the diagnostic value of diffusion kurtosis imaging (DKI) compared to mono-exponential diffusion weighted imaging (DWI) in the diagnosis of breast cancer. Methods: A systematic electronic literature search (up to September 2020) was conducted for published English-language studies comparing the diagnostic values of DKI and DWI for the detection of breast cancer. The data of mean kurtosis (MK), mean diffusivity (MD), and apparent diffusion coefficient (ADC) were extracted to construct 2 × 2 contingency tables. The pooled sensitivities, specificities, and areas under the receiver operating characteristic curve (AUCs) were compared between DKI and DWI in the diagnosis of breast cancer. Results: Eight studies were finally included, with a total of 771 patients in the same population. Pooled sensitivities were 82.0% [95% confidence interval (95% CI), 78.2‐85.3%] for ADC, 87.3% (95% CI, 83.9‐90.1%) for MK, and 83.9% (95% CI, 80.2‐87.1%) for MD. Pooled specificities were 81.1% (95% CI, 76.7‐84.9%) for ADC, 85.1% (95% CI, 81.1‐88.5%) for MK, and 83.2% (95% CI, 79.0‐86.8%) for MD. According to the summary receiver operator characteristic curve analyses, the AUCwas 0.901 for ADC, 0.930 for MK, and 0.918 for MD (ADC vs MK, P = .353; ADC vs MD, P = .611). No notable publication bias was found, while significant heterogeneity was observed. Conclusions: Although DKI is feasible for identifying breast cancer, MD and MK offer similar diagnostic performance to ADC values. Thus, we recommend that DKI should not be included in the routine evaluation of breast lesions now.


Since it is still a wide-held belief that fibrinolytic therapy can clear thrombi from deep veins only while they are fresh, we retrospectively analyzed the phlebographic results obtained in 85 patients with thrombosis of the iliac and/or femoral veins with symptoms present for 1 day to 8 weeks prior to treatment. Streptokinase, urokinase, or both drugs successively were administered in these patients for a mean of 9 days (range: 2 to 26 days). Complete or partial resolution of the thrombotic occlusion was obtained in 94%, 82%, and 69%, respectively, in those patients who presented within 3 days, 1 to 2 weeks, and 3 to 4 weeks after the first appearance of symptoms. With a delay of 5 to 8 weeks the results were uniformly poor with only 1 partial recanalization in 7 patients.


It took some time for neurology to become a medical discipline independent from psychiatry and internal medicine. Many scientists, who were specialists in different areas, contributed to its development. Webb Haymaker intended The Founders of Neurology (1953) to be a vade mecum for an historical exhibit at the 4th International Neurological Congress in Paris, held in 1949. Its 133 entries presented portraits, brief biographical sketches, and references to primary publications of a selection of the ''most outstanding'' – as determined by Haymaker's advisory committee – deceased clinical neurologists, neuroanatomists, neurophysiologists and neurosurgeons from 16 countries. Its usefulness and popularity are underlined by the publication of a second edition (co-edited by Francis Schiller in 1970), a rare phenomenon for a medical history book. Another influential book published that year was Macdonald Critchley's (1900–1997) The Parietal Lobes. It is one of very few books dealing with the many different and often puzzling phenomena resulting from lesions of the parietal lobe, such as constructional apraxia, Gerstmann's syndrome, disorders of body image, spatial thought, visuo-spatial neglect, and tactile discrimination. Critchley recognized that in the parietal lobe sensory information is linked to the dynamics of motility. He believed that probably no other book on the parietal lobe would soon appear, since the era of localization was coming to an end. By the mid-19th century scientists (e.g., François Boissier de Sauvages de la Croix, Wilhelm Griesinger) had observed eye movements during sleep. These movements did not receive much attention until the University of Chicago's Eugene Aserinski and Nathaniel Kleitman published a paper in Science in 1953, showing that the rapid eye movements (REM) during sleep, which are registered with EEG, are associated with dreaming.


Aims It is recognised that different infant growth references (GR) can alter apparent infant growth patterns. The influence of the choice of GR on apparent associations between early growth and later outcomes in research studies is unknown. Our aim was to examine whether the choice of GR influences (1) apparent infant growth patterns; and (2) associations with later anthropometry and body composition (BC). Methods Weight, height, BMI, waist circumference (WC)) and BC (four component model: fat mass (FM), fat free mass (FFM)) were measured in 209 healthy British children (mean (SD) 11.1 (3.5) yrs, 104 boys). Infant weight data were extracted from parent-held child records for birth, 3, 6 and 12wk, 6 and 12mo and converted to standard deviation scores (SDS) using British 1990 Growth Reference (UK90) and World Health Organisation (WHO) growth standards. Change in Weight SDS (ΔwtSDS) using the two GRs were compared and associations between ΔwtSDS 3–6wk and 0–12mo and later measurements were assessed, adjusting for confounders. Results ΔwtSDS calculated using UK90 and WHO were significantly different at all ages. UK90 ΔwtSDS 0–3wk was significantly <0 and ΔwtSDS 3–6wk significantly higher. WHO SDS were significantly <0 for ΔwtSDS 3–6wk and significantly higher for 12wk-6mo, 6–12mo and −12mo. In boys, ΔwtSDS 36wk was positively associated with later height, weight and FFM regardless of GR although associations were stronger for WHO than UK90 (e.g. 0.65 WHO (p=0.02), 0.57 UK90 (p=0.04)). In girls, ΔwtSDS 3–6wk was positively associated with later FM and fat-free mass index (FMI) using both UK90 and WHO, and with weight, BMI, WC only using UK90; all associations were stronger using UK90 than WHO. ΔwtSDS birth-12mo in boys and girls was significantly associated with all later outcomes except FMI, with similar effect sizes using UK90 and WHO. Conclusion This study showed that choice of GR does result in differences in infant growth patterns (1). This does in turn, influence apparent associations with later outcomes (2): effects may differ by gender and growth period. This should be considered by researchers.


Kenmooreana gen. n. contains K. eudesmiae sp. n. (type‐species) and K. trilateralis sp. n. from Western Australia, and K. nigrifax sp. n. from Queensland and New South Wales. All 3 species construct fragile white lerps on Eucalyptus spp. K. trilateralis and K. nigrifax were each collected from species of Eucalyptus belonging to different subgenera.


Introduction of PMUs to cyber-physical system pro-vides accurate data acquisition, while posing additional risk of being the victim of cyber attack. Both False Data Injection Attack (FDIA) and GPS-spoofing or timing attack can provide malicious data to the cyber system, though these two attacks require different post-attack contingency plan. Thus accurate detection of timing attack and separating it from conventional FDIA has become a very important research area. In this article, a successful detection of timing attack mechanism is proposed. Firstly, a method to distinguish timing attack and FDIA using unwrapped phase angle data is developed. Secondly, utilizing low rank Henkel matrix property to differentiate timing attack from electrical events is also presented. Finally, an experimental validation of proposed model is performed on IEEE 13 bus system using simulated GPS-spoofing attack. It can be observed that the timing attack can increase the rank 1 approximation error of Henkel matrix of unwrapped angles by 700% for 3 sec delay in GPS time-stamp. The rank 1 approximation error is increased by 500% for 2 sec delay and the increase is insignificant for 1sec delay attack. FDIA doesn't show any significant change in the low rank approximation profile of Henkel matrix.


Performance and implementation complexity between 2.4 GHz radar system with homodyne and 10 GHz radar system with super-heterodyne are compared and discussed. In particular, recently proposed architectures are examined, which are implemented by identical PLL and VCO. Both the operation of two different architectures and the superior performance of these radar systems can be understood by observing what level of signal is received based on same signal conditions. 10 GHz approach yields better performance in terms of RCS and antenna gain, but at the cost of increased implementation complexity.


In order to study the effects of Dimethoate on liver cell apoptosis in vitro,Dimethoate was added to rat hepatocyte culture fluid to get final concentration of 0,3,10,30,100 and 300 μmol·L-1 in each group.After 12 and 24 hours' exposure,apoptotic cells were observed by electron and fluorescence microscope,apoptosis rate was analyzed by Annexin V/PI method;Intracellular Ca2+ concentration,reactive oxygen species(ROS) and mitochondria membrane potential(Δψm) changes were analyzed by Fluo-2/AM,Dichlorofluorescin diacetate(DCFH-DA) and Rhodamine 123 method respectively.The results showed that after 12 and 24 hours' exposure,microstructural changes of apoptotic cells were observed;hepatic cell apoptosis rate increased,and the difference between experimental groups(apart from 3 μmol·L-1 group) and control group was statistically significant(P0.05 or P0.01);an obvious dosage-effect and time-effect were also observed.Intracellular Ca2+ concentration of 3 μmol·L-1 group was significantly(P0.01) higher than that of control group,but then decreased with increasing dosage.Intracellular ROS level increased with increasing dosage and time of exposure in the range of 3~100 μmol·L-1;however,ROS level decreased slightly in 300 μmol·L-1 group,and the difference between experimental groups(apart from 3 μmol·L-1 group) and control group was significant(P0.01).Mitochondria membrane potential(Δψm) decreased continuously after 12 and 24 hours' exposure apart from the 300 μmol·L-1 group with 24 h exposure.It was concluded that low dosage of Dimethoate can induce liver cell apoptosis,and intracellular Ca2+,ROS and Δψm changes may participate in this process.


A 20 years old man came to the outpatient clinic(infectious disease branch) with a 6-month hystory ofulceration on the right foot. He also complained of localpain and uneasy gait. He did not smoke, denied alcoholabuse, the use of illicit drugs, diabetes mellitus, the useof chronic prescribed drugs or the presence ofimmunosupressive diseases. On 3 occasions he wasseen by different physicians and was treated with oralantibiotics and local creams without improvement. Duringclinical examination he appeared healthy. A shallowulceration with clearly defined borders on the right footwas described (Figure A: note the yellowish and dryaspect of the base of the ulcer which is surrounded byreddish well defined limits). Physical examination did notreveal significant alterations, except for the presence ofan indurated spleen palpable 4 cm below the left costalmargin. Abdominal ultrasound confirmed the increasedsize of the spleen without any singularity; normal livertexture was described and no intra-abdominal lymphnodes were reported. Chest x-ray resulted normal. Stoolexamination revealed the presence of viable eggs of


The oxo-peroxo-vanadium(V) and dioxo-vanadium(V) complexes of N,N-bis(2-pyridylmethyl)glycinate (bpg−), VO(O2)(bpg) (1) and V(O)2(bpg) (2) co-crystallize in variable ratios in an anhydrous and a dihydrate phase with the overall formulation 1x21−x·nH2O, n = 0 or 2, where 0 ≤ x ≤ 1 (alternatively V(O)2−x(O2)x(bpg)·nH2O, n = 0 or 2, where 0 ≤ x ≤ 1). The seven-coordinated complex 1 contains a η2-peroxide ligand (O22−) whereas the six coordinated 2 contains a monoatomic oxide ligand (O2−) in the same position. Characteristic chemical shift differences for the vanadium atoms of the two complexes mean that 51V solution state and MAS NMR spectroscopy can be used to determine the concentration of 1 and 2 in bulk samples. Significantly, however, 51V MAS NMR spectroscopy also reports on the identity of the crystal phase. This is possible because the isotropic 51V resonances are sensitive to intermolecular interactions specific to each crystal phase. The solid-state 51V MAS NMR spectroscopic data show that the different phases do not co-precipitate but the concentration of the solute (which can be either 1 or 2) can vary. Thus co-crystallised mixtures of 1 and 2 can be classed as a molecular mixture capable of forming continuous solid solutions.


A facility has been developed for producing high quality tomographs of order one micrometer resolution. Three dimensional volumes derived from groups of adjacent tomographic slices are then viewed and navigated in a stereographic viewing facility. This facility is being applied to problems in geological evaluation of oil reservoir rock, medical imaging, protein chemistry, and CADCAM.


In this paper, the authors develop chemically synthesized pre-miRNAs (syn-pre-miRNAs) that retain the stem–loop structures for the simultaneous production of both guide (-5p) and passenger (-3p, or *) miRNA strands in transfected cells. The authors show that syn-pre-miRNAs fully recapitulate the properties of pre-miRNAs and that both 5p and 3p miRNAs can inhibit expression of sensors containing bona fide target sites.


The article analyzes the institutional framework of trade in goods in the EEC. As the framework (obstacles) are considered measures of technical regulation as the most significant to maintain the security of goods, at the same time revealed the dual nature of such measures. On the one hand, they aimed at ensuring the safety of products, and with another - should not hinder trade within the EEU.


Point your SmartPhone at the code above. If you have a QR code reader the video abstract will appear. Or use: Background and objective: Family physicians are expected to be comfortable in treating common sports injuries. Evidence shows a limited level of comfort in treating these injuries in pediatric and internal medicine residents. Studies are lacking, however, in family medicine residents. The purpose of this study is to assess the comfort level of family medicine residents in treating common sports injuries in adults and children based on their perceived level of knowledge and attitudes. Methods: This is a cross-sectional study of family medicine residents in the United Sates. A written survey of 25 questions related to sports injury knowledge and factors affecting comfort level were collected. A chi-square test was implemented in calculating P-values. Results: Five hundred and fifty-seven residents responded to the survey. A higher percentage sports medicine contribute to residents' knowledge and comfort level in treatment of common sports injuries.


Xwake is a user friendly Finite Difference Time Domain (FDTD) code for wake potential and impedance calculations of rotationally symmetric structures. Geometry boundaries are automatically meshed, or modeled, by a choice of either of two approximations, the typical {open_quotes}stepped edge{close_quotes} modeling, or the new {open_quotes}contour{close_quotes} modeling. Contouring means geometry boundaries described with curves and angles are not distorted to follow the rectangular grid; rather, the grid is adjusted to follow the contour of the geometry boundaries. It offers computer run time savings for large problems or intricate geometries for a given mesh compared with stepped edge modeling. Using stepped approximations with Xwake, on the other hand, one is able to model materials of any linear media type. Ultimately, three solutions are computed, wake potential versus wake length, wake spectrum versus frequency - a Fourier transform (FFT) of the wake potential, and wake impedance versus frequency. Xwake is an OSF/Motif application providing a graphical user interface (GUI) for ease of use. It is written in ANSI C for portability and currently runs on UNIX platforms.


To cite: de Leeuw E. J Epidemiol Community Health 2022;76:206–208. Centre for Health Equity Training, Research and Evaluation (CHETRE), University of New South Wales, Liverpool, NSW, Australia Population Health, South Western Sydney Local Health District, Liverpool, NSW, Australia Ingham Institute for Applied Medical Research, Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia


CD26, the T cell activation molecule, is a 110-kD glycoprotein that is also present on epithelial cells of various tissues, including the liver, kidney, and intestine. CD26 possesses a known dipeptidyl peptidase (DPP)IV activity in its extracellular domain ([1][1]). A paper by Wesley et al. in this


Prompted when loading the wells of the space above the column of EXPLOSIVE charge to fill low-density composition. Low density polyethylene composition is poured into the shell. For the same blocking effect of all wells is taken into account the settling time of the column of low density polyethylene composition. Such charge design allows qualitatively improve the efficiency of locking products of an explosion into the charging chamber. To increase the exposure time of detonation products. To reduce dust emissions. To improve the performance of the excavator. Fig. 2. Bibliogr. 2 the name.


The Mailing Nine or "true Paradise" apple stock has been vegetatively propagated for centuries as a rootstock for use in the production of dwarf apple trees. Mailing Nine is said to be native to parts of southern Russia (3), and is presumably a type that has adapted itself to semi-arid conditions. The stock itself is a low branching shrub, rather than a tree. As to the physiological effects in dwarfing the scions (11) of apple varieties grafted or budded upon it, very little is known. Blackman (1) states: "The influence of stock on scion is one which has puzzled plant physiologists for decades. No progress has been made as to the mechanism of the action of a dwarfing stock. ' ' The Mailing Twelve stock used in this work is one of extreme vigor among the vegetatively propagated stocks (8), closely approaching the vigor of the free-growing or seedling crab stocks in common use by American nurserymen for the production of standard budded or grafted apple trees. The two stocks, Mailing Nine and Mailing Twelve, represent very nearly the extremes in growth habit, vigor, age of fruiting, etc., found in the Pyrus makes species. Of the scion varieties used, "Whitney is a very low N tree, slowing up in growth at an early age, while Snow is an extremely high N variety, very vigorous in growth. A chemical study of the trees grown on the two stocks just mentioned should reveal something of the chemistry involved in growth extremes in apple, and possibly something of the fruiting relationships as they occur in dwarf and in standard apple trees of different varieties. All apple scion varieties are not affected in the same way by these two Mailing stocks, according to Roberts 's (14) work. Of the varieties studied here, Wealthy is only moderately dwarfed by the Mailing Nine stock, but is fruiting heavily (at the age of 6 years) on a biennial schedule. Mclntosh on Nine is decidedly dwarfed, with characteristically open top, and fruits heavily. Spy, Winesap, and Whitney are severely dwarfed, and are fruitful. All of these varieties as grown on Mailing Twelve stock are as yet entirely unfruitful (with the exception of Wealthy which fruits lightly) and are very vigorous growers. Snow on Nine is not appreciably dwarfed, however, while Snow on Twelve makes a fair growth but does not show the extreme vigor that might be expected from this combination of root and scion. York in


This article claims that the male novel of the Quiet Revolution in Quebec creates a spectacularly gendered world in which the body politic (as well as the cultural sphere as a whole: the writer, the novel and literary institutions) is defined as entirely male and the erotic body, which also becomes the raped and murdered body in many cases, as exclusively female. This focus on gendering and violence attempts to show the links between the two – that radical gendering is in itself a form of violence – and suggests that the nationalistic project, as least as set forth in fiction, is deeply compromised by its misogyny.


It is well-known that indirect strokes cause induced voltages, which can be reduced effectively by installing surge arresters. From the perspective of economics, it is too rough if a surge arrester is installed in each pole. How to design the number of surge arresters and their locations in an overhead distribution network according to some economic and technical criteria is a challenging issue in the field of smart grid. This paper formulates this issue firstly as a typical discrete optimization problem by maximizing an economic performance index. Then, an adaptive binary particle swarm optimization algorithm is utilized to search for an optimal location strategy of surge arresters. The superiority of the proposed method to binary genetic algorithm-based, binary differential evolution-based method is tested for a typical overhead distribution network in terms of the global best fitness, the optimized number of surge arresters, and the number of flashovers.


This research presents a neural network algorithm to identify the best modeling and simulation methods and assumptions for the most widespread nanofluid combinations. The neural network algorithm is trained using data from earlier nanofluid experiments. A multilayer perceptron with one hidden layer was employed in the investigation. The neural network algorithm and data set were created using the Python Keras module to forecast the average percentage error in the heat transfer coefficient of nanofluid models. Integer encoding was used to encode category variables. A total of 200 trials of different neural networks were taken into consideration. The worst‐case error bound for the chosen architecture was then calculated after 100 runs. Among the eight models examined were the single‐phase, discrete‐phase, Eulerian, mixture, the mixed model of discrete and mixture phases, fluid volume, dispersion, and Buongiorno's model. We discover that a broad range of nanofluid configurations is accurately covered by the dispersion, Buongiorno, and discrete‐phase models. They were accurate for particle sizes (10–100 nm), Reynolds numbers (100–15,000), and volume fractions (2%–3.5%). The accuracy of the algorithm was evaluated using the root mean square error (RMSE), mean absolute error (MAE), and R2 performance metrics. The algorithm's R2 value was 0.80, the MAE was 0.77, and the RMSE was 2.6.


The aim of this paper is to inquire into Luther's view on women. First of all, this paper investigates the dualisms of flesh and spirit and of man and woman that underlie traditional misogyny, and pays attention to Luther's rejection of this misogyny. On the basis of his Reformation agenda that a sinner can be justified by faith in Jesus Christ alone, Luther instead employs the logic of faith and love. He uses faith as the criterion by which to distinguish spirit/"spiritual" from flesh/"fleshly," thereby rebuffing the correlation of man to spirit/"spiritual" and that of woman to flesh/"fleshly." According to Luther, it is the presence or absence of faith that makes a person "spiritual" or "fleshly," regardless of their gender or sex. Furthermore, he emphasizes that practicing love, which is the fruit of faith, means nothing less than an ascetic life, and that this is the kind of life that mortifies one's flesh and vivifies one's spirit.On the basis of this logic of faith and love, Luther denies another dualistic attitude that separates the convent life from the family life, relating nuns to the spiritual estate and wives/mothers to the secular estate. Luther views wives and mothers as belonging to the spiritual estate because they believe in God's word, treat what they do as their vocation, and do not withdraw from exercising love in real life. Luther also sees a wife as a woman who is specially and specifically chosen by God for a man and is his closest neighbor to serve in accordance with the law of love. A mother is the mistress of a family, which Luther considers to be the most important and primary institution ordained by God; she is also her children's apostle, bishop, and priest.


This article discusses the first efforts of non-governmental organizations and Indigenous communities in Canada to force governments to move more aggressively to mitigate climate change through constitutional litigation. The claimants argue the failure of the Canadian government to implement adequate climate change policies violates the constitutionally protected rights under the Canadian Charter of Rights and Freedoms, such as the section 7 right to life and security of the person, and the section 15 right to equality. By comparing the developing Canadian actions to recent international jurisprudence in the Netherlands and the United States, the authors analyze the hurdles these claims will need to overcome to be successful at the Supreme Court of Canada — justiciability and whether the Charter even provides protection for environmental rights.


Scientists show that the presence of bright-shining noctilucent clouds have increased in the northern third of the United Sates and the lowest parts of Canada.


An adjustable shelf system for installation in combination with a non-load bearing wall which does not require penetration of the wall for support is disclosed. The adjustable shelf system is particularly well suited for use in combination with non-load bearing walls of the type supported intermediate a building foundation and an upstanding load bearing frame which includes a top track member having channels for receiving studs and prefabricated wall panels. Shelves are supported on brackets which are attached to laterally spaced, upstanding tubular support legs having a channel formed within one side wall portion. A cushion strip is confined in the channel intermediate the upstanding tubular support legs and the non-load bearing wall thereby preventing abrasive contact of the tubular support legs against the adjacent wall paneling. In a preferred embodiment, an extendable tubular member is coaxially received within the central chamber of each of the tubular support legs and projects above the tubular support legs to an elevation substantially flush with the top side surface of the top track member. Fastener means are provided for mechanicaly interconnecting the extendable tubular member to the top track member for preventing lateral displacement of the tubular support legs relative to the wall paneling.


This study analyzes health spending efficiency in developing Asia. The result shows universal health coverage service coverage index and population density as key determinants of health spending efficiency. While East Asia has the highest average technical efficiency score, Caucasus and Central Asia has the highest average allocative efficiency score. Overall, there is significant potential for improving both technical and allocative efficiency in health-care expenditures across developing Asia.


The purpose of this investigation is to attempt by correlation of chemical-physical factors to ascertain if any one of the necessary features might act as a factor limiting growth and reproduction of either plants or animals. The body of water used in this investigation is Eagle Mountain Lake, a reservoirs approximately five years of age.


This letter considers hybrid analog-digital beamforming with discrete-phase shifters for multiuser multiple-input and single-output (MISO) downlink transmission in millimeter-wave (mm-wave) channels. A max-min signal-to-interference-plus-noise ratio (SINR) fairness problem is formulated. Owing to the discrete-phase constraints, this problem is a mixed integer nonlinear program (MINP) and is generally NP-hard. To handle it, an alternating optimization approach is employed. Specifically, for the digital beamformer, zero-forcing (ZF) beamforming is utilized. For the discrete-phase analog beamformer, we first derive an equivalent continuous reformulation and then solve it by leveraging an inexact majorization-minimization (MM) algorithm, which is built upon the first-order method and MM update. Simulation results show that the proposed design can almost achieve the optimal performance of the exhaustive search method, and can approach the optimal full-digital performance with increasing resolution of the discrete-phase shifters.


A method of calculating the pressure from the velocity field measurement data by using the PIV contactless technique is considered in the work. The pressure distribution was calculated by using the...


developed homografts and profound hypothermia and circulatory developed techniques including the trapdoor technique in arterial switch operations, double switch operation for patients with cc-TGA, and the Mee technique for intramural coronary arteries. I been greatly influenced by these two legends. In 1998, we developed a new surgical technique, the so-called Sano shunt (RV-PA shunt), as the first stage palliation for hypoplastic left heart syndrome (HLHS). Other new procedures include RV/RA exclusion to treat severe forms of Ebstein ' s anomaly in 1996, staged biventricular repair of pulmonary atresia and intact ventricular septum in 2001, and cerebral perfusion during aortic arch repair in 1996. More recently we started to research progenitor cell therapy for single ventricle patients with heart failure, which went to Phase I clinical trial in patients with HLHS in 2011. This was the first successful clinical trial of cardiac progenitor cell therapy in a pediatric population. We have now finished Phase I and II, and began Phase III (a multi-center study) in August 2016. My mentors always told me to be an academic and innovative surgeon and this is what I want to share with the next gener-ation.


The aim of this meta‐analysis of randomized trials was to assess the effects of SGLT‐2i on the overall incidence of malignancies and on different types of cancer, summerizing the results of trials with a duration of at least 1 year. This was done in light of the effect of SGLT‐2 inhibitors (SGLT‐2is) that has been highlighted by some studies, showing an increased incidence of bladder cancer, particularly with use of empagliflozin.


Objective To construct lentiviral expression vector of rat IP3R1 gene,and identify its silencing effect by using PC12 cell lines. Methods Oligo DNA sequences of 4 pairs of miRNA,named as miRNA1,miRNA2,miRNA3 and miRNA4,were designed according to IP3R1 gene sequence (GenBank:NM_001007235). The single strand of oligo DNA was annealed to form double strand DNA,and then connected with the empty plasmid pcDNA TM 6.2-GW/EmGFP-miR. By using gateway technology,the expression vector pcDNA TM 6.2-GW/EmGFP-miR-IP3R1 was linked into lentiviral destination vector pLenti6/V5-DEST to form the lentiviral expression vector pLenti6/V5-DEST-IP3R1,then it was transformed into infectious lentiviral particles and to infect PC12 cell lines. Silencing effect of gene IP3R1 was detected by Real-time PCR and Western blot. Results The sequence of expression vector pcDNA TM 6.2-GW/EmGFP-miR-IP3R1 was proved correct using sequencing method. After the transfection of letivirus vector pLenti6/V5-DEST-IP3R1 into PC12 cell lines,the IP3R1 mRNA and protein level were down-regulated 48h later,of which miRNA2 and miRNA3 sequence showed the best silencing effect,and the expression of IP3R1 in the blank control and negative control showed no significant changes. Conclusions Lentiviral expression vector pLenti6/V5-DEST-IP3R1 was constructed successfully. pLenti6/V5-DEST-IP3R1 may render the IP3R1 expression in PC12 cell lines down-regulated,and it provides a foundation for studying the function of calcium release channel IP3R1.


K. HAYAT, W. PUECH and G. SUBSOLLIRMM, UMR CNRS 5506, University of Montpellier II,161, rue Ada, 34392 Montpellier CEDEX 05, FranceE-mail: firstname.lastname@example.com, firstname.lastname@example.com and firstname.lastname@example.com. GESQUIERELSIS, UMR CNRS 6168, Aix-Marseille UniversityIUT, rue R. Follereau, 13200 Arles, FranceE-mail: firstname.lastname@example.com present a scalable encoding strategy for the 3D facial data in various band-width scenarios. The scalability, needed to cater diverse clients, is achievedthrough the multiresolution characteristic of JPEG2000. The disparate 3D fa-cial data is synchronously uni ed by the application of data hiding wherein the2.5D facial model is embedded in the corresponding 2D texture in the discretewavelet transform (DWT) domain. The uni ed le conforms to the JPEG2000standard and thus no novel format is introduced. The method is e ective andhas the potential to be applied in videosurveillance and videoconference appli-cations.Keywords : JPEG2000, discrete wavelet transform (DWT), scalability, synchro-nization, videosurveillance, videoconference, data hiding, LSB, 3D, 2.5D, facedata, multiresolution


The output of pipelines in Northeast China is reduced year by year. The determination for safe and economic operation schemes of the Northeast pipelines in future seriously depends on the variations of wax deposition of Daqing crude oil in Northeast pipelines under outputs reductions. Based on the achievements from the previous studies on wax deposition of Daqing crude in the Northeast pipelines and the forecast operation plans, forecast and analysis for wax deposition in the Northeast pipelines in future are implemented in this paper,and some significant conclusions and suggestions are given.


J. A. Nweke Abstract This paper is an investigative study conducted with the objective of finding the resultant effect when Minimalist Theory is applied to Igbo noun phrase in sentence construction. Minimalist programme is the most current syntactic theory founded and developed by Noam Chomsky and his associates in 1996, with the aim of enabling syntacticians employ only the basic minimum apparatus required for the description (and accounting for the structure) of sentences in all human languages. The programme is designed in order to remove any non-essential and superfluous apparatus which may constitute problems in syntactic description and hence make way for the use of only essential apparatus during syntactic analysis. With the latest approach to the study of grammar, the minimalist programme had carefully eliminated many of the concepts that existed in earlier syntactic theories such as Traditional Grammar, Phrase Structural Grammar, Transformational Generative Grammar and Government and Binding Theory. The theoretical framework is based on the concept of Computational System, which is the operation where fully formed words selected from the lexicon are combined in pairs through a process called Select and Merge – which means combining new items with existing items. This paper begins with an Introduction and moves on to a Theoretical Concept of Minimalist Programme. It highlights on the impact of word order, on concept of noun phrase in Igbo language based on minimalist approach, on the application of major minimalist concepts to Igbo noun phrase, such as description of Igbo nominal, and on a bipartite description of Igbo noun phrase using minimalist approaches. Finally is the conclusion which discusses minimalist programme as a solution to the problems created by other syntactic theories.


This paper develops a new combined wealth measure using data from the Survey of Consumer Finances, by augmenting data on net worth with estimates of defined benefit (DB) pension wealth and expected Social Security wealth. We use this combined wealth concept to explore retirement preparation among groups of households in their pre-retirement years (40-49 and 50-59) and also to explore the concentration of wealth. We find evidence of moderate, but rising, shortfalls in retirement preparation. We also show that including DB pension and Social Security wealth results in markedly lower measures of wealth concentration. Trends toward higher concentration over time are also somewhat moderated.


The invention relates to multi-functional ribosomal protein nucleolin and application thereof, specifically to application of nucleolin as a molecular marker for the intestinal cancer of human beings and application of nucleolin to preparation of a preparation or kit used for detecting and diagnosing the intestinal cancer of human beings and a therapeutic for the intestinal cancer, belonging to the field of biotechnology. According to the invention, ELISA detection is carried out on both the blood plasma sample of a patient with the intestinal cancer and a normal control blood plasma sample; detection results show that the level of nucleolin in the blood plasma of the patient with the intestinal cancer is substantially higher than the level of nucleolin in the normal control blood plasma sample and that nucleolin is highly expressed in the intestinal cancer and secreted to blood; thus, nucleoli can be used as a noninvasive marker for diagnosis of the intestinal cancer. The invention further provides application of nucleolin to preparation of a diagnostic reagent and kit for the intestinal cancer and a drug with nucleolin as a target and for treatment of the intestinal cancer. The invention provides a novel assistant determination means for diagnosis of a colorectal cancer.


Brick was proved to be one of the main building materials in the region of today's Serbia, especially in the time of late antiquity and in the following medieval time. Hence, the idea was born to make a comparison between the main characteristics of late antique and medieval bricks and brickworks from this region that could confirm the continuity and variety of its use. A question of evolution of the use of bricks was partly based on comparison of their estimated properties and also on comparison of applied building techniques and known characteristics of brick production. It has been confirmed that although it is possible to discuss and confirm the continuity in the use of bricks and adequate building techniques, up-to-date research based on quantitative analysis of historical bricks do not offer enough comparable data regarding their quality. Therefore a new field of possible qualitative research is needed in the future.


Biblio-MetReS is a single-thread data mining application that facilitates the reconstruction of molecular networks based on automated text mining analysis of published scientific literature. This application is very CPU-intensive, requiring High Performace Computing (HPC). Due to the amount of execution tasks, it can be quite slow. Those tasks are repetitive and consist in mining the information from large sets of scientific documents, a process where the time-cost of the application could be improved through paralellization.
 This paper presents a parallel version of Biblio-MetReS. The multithreading application P(arallel)-Biblio-MetReS distributes the work among copies of the same Java class, each mining a collection of documents obtained in a previous search phase from different literature sources of Internet. In this article, we compare performances between the parallel and non-parallel versions of the application and discuss scalability issues on multi-threading systems in the context of this application. Furthermore, we also optimize memory management and reutilization of document parsing results. Our experimental results corroborate the good performance of P-Biblio-MetReS, pinpointing specific aspects that still need to be improved.


Based on traditional methods of economic analysis,this paper is to explore the mechanism between ST business incubator and regional economic development.Authors think that ST business incubator have been contributing to the regional economic increase in the international point of view.It has been demonstrated that there is stronger outside consistence between ST business incubator and regional economic development in China.In the end,this paper draws four theoretical conclusions about the mechanism.


IT is happily unnecessary at the present time to commend this edition to the attention of scholars. In the opinion of all competent judges the great promise of the first volume of this important work, of which I spoke in the Preface to my Life and Letters of Cicero, in 1880, has been fully sustained in the two that have succeeded, and it has distinctly taken its place in the front rank of English editions of the classics, as one showing not only great industry and scholarship, but also singular freshness and virility. There is no need now to do more than to inquire what special contribution this third volume makes to the progress of the work. It will be seen that in accordance with the announcement made in the Preface to the second volume, 1886, Mr. Purser, who had largely assisted Prof. Tyrrell before, especially in the tedious work of the collation of MSS., is now associated with him as joint editor. What exact share each may have taken, one cannot of course tell; but I venture to think that, whatever the cause, the result, as a whole, is, without any loss of vigour, a distinct gain in soundness. The fault of the first volume certainly was too great readiness to admit clever conjectures into the text without adequate discussion or sufficient foundation. In the present volume the mere conjectures actually admitted into the text are comparatively few and are not mostly of a very startling character. By far the most brilliant of these is not due to the editors, who nevertheless may claim some credit for being the first to adopt it in the text, namely Dindorf's aKpa. Tvpiwv pwra for the ' aKpar-^peov iura ' of the Medicean MS. in Att. v. 12, given in all edd. as aKpwrrjpiwv ovpia, which is supposed to mean ' signs of fair weather from the mastheads.' ' The reading in the text,' say the editors, 'was admirably restored by L. Dindorf from a fragment of Archilochus (54, Bergk) :


Abstract The premise of this paper is that the chemical potential of water strongly influences aging reactions in seeds, and that there will be an optimal chemical potential of water for seed longevity. If this is true, the optimum moisture content for storage and the optimal drying protocols should vary with the storage temperature, but should be predictable from water sorption isotherms. Isotherms for pea, soybean and peanut are given for temperatures between 65° and −150°C. Relative humidity/moisture content relationships were determined directly for temperatures between 5° and 50°C using saturated salt solutions. At extreme temperatures, isotherms were calculated from heat capacity measurements using differential scanning calorimetry or extrapolations of van't Hoff analyses. The family of isotherms was used to predict optimum moisture contents at storage temperatures between 65°C and −150°C. The optimal moisture contents for these three species are consistently shown to increase as the storage temperature is lowered.


Under Lakitelek Aduit Education College we took part in a field research in Burgenland uvo times for a week. We managed to find indigenous Hungarian inclusions. These are the last episodes of Hungarian-Austrian community. Their cultural and education system is developped, even though the community is towards its annihilation. Within the framework of the questionnaire survey, we processed the answers given for the questions related to population, education, minority life and language. The overall picture of the research will be evaluated with the help of a SWOT-analysis.


Background: At present, surgery is the best method for chronic anal fissure, but by acquiring more knowledge about the pathogenesis and function of internal anal sphincter, non surgical treatment such as using of Glycerin trinitrate, Isosorbide, Bethancol, Diltiazem and Butilinum toxin has been suggested. There is controversy about using of L-Arginine. The aim of the present study was to compare the effect of L-Arginine (chemical Sphincterotomy) with lateral internal Sphincterotomy (surgical Sphincterotomy) in treatment of chronic anal fissure. Materials and Methods: This clinical trial study was performed on 60 patients referring to our hospital complaining for chronic anal fissure. They were randomly divided in tow groups of equal number: patients undergoing internal Sphinctrotomy (control), and using of topical L-Arginine gel (case). All of the patients under study where followed for three months, data about pain, bleeding, and wound healing were recorded, and analyzed by SPSS 11 software, chi- square and t-test. Results: The results observed in this study showed that in case group, rectal bleeding discontinued in 70% and pain controlled in 70%, while wound healing occurred in only 26.7%. in control group, 100% had no pain and no bleeding after treatment and wound healing occurred in 56.7% . Conclusion: Local application of L-Arginine can not replace internal sphinctrotomy, but can be used when patient is unwilling for surgery and in cases with underlying disease.


Context: Cardiovascular disease (CVD) is one of the leading causes of morbidity and premature mortality across Spain. According to the World Health Organization (WHO), 80% of these premature deaths are preventable by controlling cardiovascular risk factors. Community pharmacists (CPs) are well situated to provide professional educational advice and implement interventions for the reduction of CVD. Aims: To analyze the impact of community pharmacists' interventions on cardiovascular risk factors and CVD prevention in Spain. Methods: Two independent reviewers searched PubMed/MEDLINE; SCOPUS; Cochrane Central Register of Controlled Trials (CENTRAL); EMBASE; National Regional Database (LILACS BIREME); CINAHL; Pharm-line; ClinicalTrials.gov; ISRCTN; DOAJ (Directory of Open Access Journals), International Pharmaceutical Abstracts (IPA), the Spanish National Research Council (CSIC), WHO ICTRP, SCIELO and opengrey.eu and Google Scholar and considered research published between January 2000 and August 2020. The Cochrane risk of bias (RoB2) and ROBINS-I tools were used to evaluate the randomised/quasi-randomised controlled trials and the nonrandomised studies of interventions (NRSI), respectively. Results: The database search resulted in 457 items from which fourteen met our inclusion criteria. A total of 4,250 participants, aged 18 to 85, were included in the pharmacists' interventions offered in the form of medication reconciliation and patient education. Studies showed a beneficial effect of CPs intervention on medication reconciliation and the control of hypertension, dyslipidaemias, obesity, and diabetes. However, evidence on smoking cessation and alcohol advice services is meager. Conclusions: This study suggests that community pharmacist counselling and personalized intervention could contribute to improving cardiovascular outcomes in Spain.


The world is changing at an ever‐increasing rate, and that includes the world of water. Every day, utility managers, engineers, chemists, operators, and other professionals must deal with financial, environmental, and technological challenges as they strive to provide the best quality water and the best service to their customers. The New Product Technology Showcase, presented at the AWWA Annual Conference and Exposition, displays the latest innovations that have come from some of the most creative minds and companies in the industry. In its seventh year, the showcase features practical and useful products and services that advance or enhance a current technology, have real‐world applications, and are commercially available. This special Journal section includes summaries of some of the products that were displayed.


This paper shows under which conditions loan securitization, e.g. collateral debt obligations (CDOs) of banks can increase the systemic risks in the banking sector. We use a simple model to show how securitization can reduce the individual banks' economic capital requirements by transferring risks to other market participants and demonstrate that systemic risks do not decrease due to the securitization. Systemic risks can increase and impact financial stability in two ways. First, if the risks are transferred to unregulated market participants there is less capital in the economy to cover these risks. And second, if the risks are transferred to other banks interbank linkages increase and therefore augment systemic risks. We analyze the differences of CDOs (true sale) and credit default swaps (synthetic) in contributing to these risks. An empirical analysis finds a significant relationship between systemic risk and CDO issuance for monthly data for the years 2000 until 2005.


PurposeCompanies are increasingly aware of the importance of delivering economic, social and environmental benefits through sustainable innovation. This study aims to examine how companies manage tensions derived from sustainable innovation and identify internal and external factors that facilitate its successful implementation in the food industry.Design/methodology/approachAn abductive and qualitative research approach was followed. Data from a multinational food manufacturer were collected from a variety of sources, which included 23 in-depth interviews with respondents from 9 different countries as well as public documents of the company under study.FindingsResults suggest that there is no "one-size-fits-all" strategy for dealing with tensions (derived from sustainable innovations), and more than one type of strategy (i.e. win–win, trade-offs) can be used simultaneously. In addition, sustainable innovation drivers do not seem to operate in isolation and follow a particular pattern where external factors motivated the development of a new set of values, which in turn were picked up and integrated into transformations at the strategic and operational level.Originality/valueThe study contributes to the theoretical and practical discussion on sustainable innovation management by providing real business case evidence of how corporate tensions derived from sustainable innovation are managed and offers a comprehensive taxonomy of sustainable innovation drivers in the food industry.


Intergranular stress corrosion cracking has occurred in BWR environments in non-sensitised, cold-worked austenitic stainless steel materials. The affecting parameters are so far not fully known, but deformation mechanisms may be decisive. The effect of cold deformation and nitrogen content on the deformation behaviour of austenitic stainless steels was investigated. The materials were austenitic stainless steels of AISI 316L type with different amounts of nitrogen (0.03...0.18%) and they were deformed in tension 0, 5 and 20% before further investigations. The investigations were focused on the dynamic strain ageing (DSA) behaviour as a function of nitrogen level and deformation. A few crack growth rate measurements are performed on nuclear grade AISI 316NG stainless steel with different degrees of deformation (0, 5 and 20%). The effects of DSA on mechanical properties of these materials were evaluated based on peaks in tensile strength and minimum in ductility in the DSA temperature range. Also the strain rate sensitivity in the DSA temperature range was investigated. Internal friction measurements were performed in the temperature range of -100...600 C for determining nitrogen interactions with other alloying elements and dislocations. The results show effects of nitrogen on the stainless steel deformation behaviour, i.e. clear indications of dynamic strain ageing: serrated yielding, negative strain rate sensitivity and changes in the internal friction behaviour as a function of nitrogen content and amount of deformation. The apparent activation energy calculated from the DSA serration occurrence map corresponds to that of nitrogen diffusion. Fully intergranular cracking was obtained in the 20% deformed, nonsensitised AISI 316NG stainless steel in simulated BWRenvironment. The crack growth data and the mechanism are discussed based on the unstable plastic flow of the material.


Inventory network administration works at three levels, vital, strategic and operational. While the vital approach for the most part relates to the streamlining of system assets, for example, outlining systems, area and assurance of the quantity of offices, and so on., strategic choices manage the mid-term, including creation levels at all plants, gathering strategy, stock levels and part sizes, and operational choices are identified with how to settle on the strategic choices occur temporarily, for example, creation arranging and booking. This paper gave an itemized meaning of Jigs and apparatuses, and furthermore distinguished the various focal points that are related with the utilization of jigs and apparatuses in assembling to include: generation increment, cost diminishment, compatibility what's more, high exactness of parts, decrease of the requirement for investigation and quality control costs, diminishment of mishap as security is enhanced, computerization of machine instrument to a considerable degree, simple machining of mind boggling and overwhelming parts, and also low inconstancy in measurement which prompts to steady nature of made items. The work likewise clarified that since the configuration is subject to various elements which are examined to accomplish an ideal yield, that jig and installations ought to be made of inflexible light materials to encourage simple dealing with. The paper primarily examines and investigates how to understand the enhancement of vital and strategic choices together in the inventory network. Hence, a store network arrange (SCN) plan issue is considered as a vital choice furthermore, the sequential construction system adjusting issue is taken care of as a strategic choice.


By Sheikh Mahmoud Mustafa Almagzoub, a lecturer at the faculty of preaching and the religious fundamentals at the Islamic University: What do I hear?......What is the unfortunate anchor saying!.... Fire is eating up Neighborhoods of Beirut. The fire fighters are unable to determine where it comes from, so they stood confused and rigid. The hospitals were the destination for every patient from everywhere that seeks cure. Today the hospitals have horribly announced there is no medicine, food, nor place for another injured. The anchor calls in desperation for the people, who will be killed by stray bullets, blind rockets, and evil missiles, to go out and protest against the tyrants that play with the souls of the week and the poor and opened the way to harvest thousands of lives…… Truly Is that happened??.. Or is it a nightmare I can't get rid of its tragic influence and horror! Who can believe this incredible news???


In today's economic climate, improving the efficiency of labour has become more pressing than ever. Labour productivity is influenced by several factors, but buildability is among the most important. A thorough search of the literature, however, revealed a dearth of quantitative investigations into its effects on an integral, labour intensive, trade of in situ reinforced concrete material; namely, formwork. Therefore, the objective of this research is to quantify the relationship between: a) perimeter configurations; b) plan geometry; c) curvature intensity; d) surface area, and formwork labour productivity of walls, which constitute major parts of many construction projects. To achieve this objective, a large volume of productivity data was collected and analysed using the multiple categorical-regression method. The results obtained show significant effects of the factors investigated on labour productivity, which can be used to provide designers and construction managers with tangible feedback on the impacts of the geometric buildability factors investigated upon the efficiency of operatives.


This research aimed to determine the isokinetic strength differences between two groups of athletes (Taekwondo and track-and-field athletics) and to analyse factors that possibly contribute to the differences. We examined possible differences in peak power output and power ratio between agonist and antagonist thigh muscles of the knee. The sample consisted of 20 respondents: Taekwondo athletes (n=10; age 19±2.4) and track-and-field athletes (n=10; age 18±2.6). For this study, a valid test (CV