Technical and legal aspects of the current Russian legislation on weapons turnover and the practice of its application are investigated. Certain provisions of the Federal Law "On weapons", the Rules of civilian and service weapons and ammunition turnover on the territory of the RF, other legal acts regulating the licensing system are considered from the perspective of optimizing the state licensing policy. The examples of logical errors made by legislator in the development of legal structures determining the procedure for obtaining license for weapon purchase and permissions for its storage and carrying are given. Provisions of Article 13 of the Federal Law "On weapons", paragraph 63 of the Rules are criticized. Taking into account law enforcement practice, the proposals to change the wording of these provisions of legal acts are made. Shortcomings in the organization of work of police officers controlling the civilian weapons trafficking are revealed. It's proposed to clarify the powers of police officers by making appropriate additions to the departmental legal acts regulating the police powers to control civilian weapons turnover. The provisions of the legislation on administrative responsibility for violation of certain rules of civilian weapons turnover are analyzed. The lack of the object of administrative offense provided by new edition of part 1 of Article 20.13 of the RF Administrative Offences Code is stated. This is due to the lack of legal rules of shooting for gun owners and citizens studying safe gun handling in sports and educational establishments. The proposal to develop such rules is made.


The aim of the present study is threefold. The first is that whether there is any difference between different proficiency level language learners 'use of spatial prepositions. The Second aim is to reveal that if the native language of the participants has any effect on applying the appropriate prepositions and also to find which spatial preposition is difficult to acquire. The present paper examines the usage of English spatial prepositions by selected Persianspeaking English learners in Mehr Aein institute in Ghorveh, Kurdistan. To do the study, 100 Persian-speaking learners of English language from different classes in Mehr Aein Institution, Ghorveh were randomly Chosen. The participants were female and male EFL learners. Their ages were ranging from 10 to 27 years old. In order to determine their level of proficiency, the participants were asked to answer an English placement test. Based on the results of the placement test they were classified into three levels, Elementary (n=13), intermediate (n=49) and advanced (38). Then considering their levels, they were given a questionnaire assessing their knowledge of English spatial prepositions and they were asked to answer it. Finally the errors on preposition usage were extracted and analyzed. The results of the study indicate that there is a significance difference among different proficiency level language learners' use of spatial prepositions. Findings indicate that most Iranian learners of English had difficulty in finding appropriate preposition. It was also found that a large number of errors were due to the interference of the learners native language (Persian). The results show the prominence of inter-lingual errors compared to the intra-lingual errors. The paper is written on the idea that the Persian language as the native language interferes with using English prepositions by Iranian EFL learners and leads to lots of prepositional difficulties. After the data were collected and analyzed, L1 interference was proved. The implications of the present research can be used for researchers, teachers and learners.


Abstract The Asia-Pacific is dominated by offshore production. In 1936 the first offshore wells to be drilled in the open sea were located in Brunei. However, real growth in global offshore drilling did not occur until the 1960s, after opportunities on land had begun to decline. Well numbers then peaked in 1981 following a decade of fluctuating and rising oil prices. After a steep drop, exploration drilling levels have now stabilised, boosted by higher oil prices and the appearance of new opportunities through improved technology, but limited by the disappearance of drilling prospects in mature regions. On average just under 1000 exploratory offshore wells are drilled globally each year of which a quarter are located in this region. Around 20% of global exploratory wells are now in deepwater. In the last decade reductions in available targets in shallow waters have been counter-balanced by moves towards increasing water depths. What is the future for the Asia-Pacific; how has drilling activity and expenditure moved here and how will it move? In particular what do changes in activity mean for geoscientists engaged in exploring for and developing the region's oil and gas? Estimated offshore well expenditure in the region is shown in the below. Drilling costs vary enormously but the cost of the rig is usually between 25% and 30% of the well cost. The engineering programme makes up between 35% and 45%, depending on the total depth of the well and whether drilling problems are encountered. Support services, including transport such as boats and helicopters, make up between 20% and 30% of total costs which leaves the cost of the geological programme, depending on well objectives, at just 5% to 10% of the total. Seismic expenditure on a project, including acquisition, processing and interpretation, is roughly a third of that allocated to drilling exploratory wells. Thus it attracts around four times as much spending on an exploratory project as the geological part of a drilling programme. It is forecast that around US$22 bln will be spent over the next 5 years on all offshore drilling in the Asia-Pacific region and an additional $7bn will be spent on seismic data. Thus around $8.5 bln will be allocated to geologists and geophysicists. This paper will consider regional exploratory activity and determine what share in the global money pot geoscientists working in different parts of the region can really look forward to. Presented at: 2005 South East Asia Petroleum Exploration Society (SEAPEX) Conference, Singapore, 2005


A technique is described for operating a prism to dielectric thin-film waveguide system over a wide frequency band from a conventional broad-band source of the dye-laser type. The continuous coupling bandwidth can extend, typically, over a frequency range of twice to three times the center frequency. The experimental tolerances have been established and are shown to be within the capability of present-day technology.


When formulating a leak-before-break case for a component in a pressurized system, it is essential to quantify the opening area associated with a crack that is subjected to the tensile stresses that are appropriate to normal operating situations. In a paper presented at the 2002 PVP Conference, the author presented a simple and exact method, based on the strip yield representation of plastic deformation, for calculating the area. The method was validated against the known result for the case of an isolated two-dimensional crack in a uniformly stressed infinite solid, but the method has general applicability. Special consideration was given to the case where plastic deformation is limited, as is usually appropriate for normal operating situations, and the method then simplifies considerably. This paper shows that the method, as it is applied to the limited plastic deformation situation, gives results which are the same as those obtained by use of the equivalent crack procedure, where an actual crack is replaced by an effective elastic crack, which is longer than the actual crack by an amount which is related to the flow properties of the material and the applied loadings. To illustrate the usefulness of the author's method, it is applied to a specific stress distribution as might arise from a combination of pressure induced and weld residual tensile stresses.Copyright © 2003 by ASME


Daebong persimmon, one kind of alkalinity foods, which is rich in saccharide such as glucose and fructose can help for contraction and secreting of intestine. Daebong persimmon was used for substitution of water in domestic wheat loaf bread and affacted quality characteristics. The basic ingredients for domestic wheat loaf bread consisted of domestic wheat flour (1000g), live-yeast (30g), sugar (60g), salt (15g), shortening (30g), yeast food (1g), non fat dried milk (40g), water (650g). The moisture content of persimmon puree was 96.69% and was used for substitution of water 10%, 20%, 30%, 50% and 100%, respectively. During the fermentation, the expansive forces decreased when increased the addition of persimmon puree. The loaf breads which were cooled at room temperature after baking were measured volume value from 2173.33 to 1760.00 when increased addition persimmon puree. The crust and crumb of loaf breads decreased also when increased the addition of persimmon puree from 61.03 to 42.79 and from 80.90 to 70.97 of L value, respectively. Whereas, both a value and b value increased from –0.28 to 4.24 and from 16.50 to 27.98. Hardness, gumminess and chewiness trended of increasing when increased the addition of persimmon puree. The cell of loaf breads was dense when increased the addition of persimmon puree similar with the effects of expansive force. The loaf bread of addition 50% of persimmon puree had a high scores and high preference on the appearance, smell and taste of sensory evaluation. Whereas, the lowest score was obtained on 100% addition of persimmon puree of loaf bread. A high hardness value gave a bad preference. So 50% addition of persimmon puree of loaf bread obtained the best effect overall. FPP-16


Summary. P‐selectin is an integral membrane glycoprotein stored in the secretory granules of platelets and endothelial cells. To determine whether soluble P‐selectin may be present in the circulation of healthy humans, we used a sandwich immunoassay to assess citrated plasma from 50 subjects. P‐selectin was present in concentrations ranging from 19 to 521 ng/ml (mean ± SD = 121 ± 84 ng/ml). The apparent molecular weight of P‐selectin immunoisolated from platelet‐poor plasma was similar to that of the detergent‐soluble form isolated from platelet membrane. Plasma levels of P‐selectin were unaffected by the following procedures: (1) drawing of blood in the presence of protease inhibitors; (2) stimulation of platelet‐rich plasma with aggregating agents; (3) ultracentrifugation at 100000 g for 120 min at 4°C or filtration through a 0·22 μm membrane; or (4) preincubation of platelet‐poor plasma with immobilized anti‐platelet glycoprotein Ib monoclonal antibodies. It appeared that plasma P‐selectin did not result from the in vitro activation of platelets, nor was it derived from platelet microparticles. We also found that plasma P‐selectin levels were significantly elevated in patients with thrombotic thrombocytopenic purpura (12 patients, 332 ± 184 ng/ml, P<0.001) and haemolytic uraemic syndrome (17 patients, 297 ± 191 ng/ml, P < 0.0001), as compared to the normal levels. Thus, these data should facilitate the study of the pathophysiological significance of circulating P‐selectin.


Regarding the experimental conditions for low temperature oxidation of coal samples,field conditions of ventilation and face geometry in face gob,using similar criteria,this paper established the mathematical model of CO emission prediction in gob based on the experimental conditions,and applying the model the site face.Spontaneous combustion of residual coal in gob has related to air leakage.Through the numerical simulation of leakage airflow field in goaf of Beizao mine 4402 face by using FLUENT software,the paper calculated the air leakage resulting spontaneous combustion of residual coal in gob,which provided the condition for applying model to predict the indication range of CO emission accurately in site gob.


Based on datebase technology and Object Oriented Programming Method(OOPM),and combined with the optimal breeding in berity breeding engineering of breeding pigs,datebases were designed for boars,sows and decendants,then the heritability,repeatability and breeding value were calculated;a heredity breeding analysis system was established for breeding pigs,and thus the quality and efficiency of producing breeding pigs was improved.


Using the West-Eastern Divan orchestra as a central referent, this essay outlines a modest utopian claim for music in our times. Set against the postmodern belief that music can only be understood responsibly by contextualizing it within the densely particularized networks of its specific localities, the essay argues for musical labor as a productive site for overcoming dangerously ossified sets of social relations. The essay detects in the late work of Edward Said a new vigilance toward the limits of 'worldliness', a conceptual orientation with which Said had become widely associated. Instead of merely indicating another site of cultural production, musical performance in the West-Eastern Divan orchestra, also becomes a site of productive forgetting. Against the identity-based forms of belonging and origin characterizing the stalemate of Israeli–Palestinian relations, Said found in music a mechanism for setting adrift identity from its contextualized locale.


Depth diffusion of acoustic energy in the finale of acoustic pulses has been observed for transmissions of 1 Mm (Slice89, Mid‐Pacific), 3.5 Mm (ATOC, California to Hawaii), and 5.1 Mm (ATOC, California to Christmas Island). This depth diffusion is a measure of the strength of internal waves in the main thermocline. A measure of the strength of internal waves is defined as the variance of displacement at a reference buoyancy frequency of 3 cph. The standard Garrett–Munk spectrum has a strength of 50 m2. In the case of Slice89, an internal‐wave strength of 25 (+/−) 10 m2, was observed (July 1989). Internal‐wave strength will be presented for the two ATOC location paths, for dates beginning in November 1995. Information from identifiable time fronts in the early‐arriving part of the pulse will also be presented. [Work supported by ONR and by the Strategic Environmental Research and Development Program through ARPA.]


Manufacturing processes involve the input of high quality energy and/or dissipation of low quality energy to manipulate a material; similarly the input of high quality material usually leads to the generation of low quality materials. A useful output involves the operation of conventional processes including a wide variety of functions such as lubrication, air compression, cooling, heating, pumping, etc., which have, on the one hand, high energy and material consumption and, on the other hand, losses due to an inherent departure from reversible processes. This paper presents an energy-flow methodology to determine the ratio between the additional energy required per useful energy unit for the manufacturing processes. As an application of the method proposed in this work, an assembly and welding production line is shown as a case study. This process is a common technique used in the manufacturing industry and its energy consumption depends on several parameters e.g. heat and electrical input. As a result of this study, the energy consumption of the production line has been reduced by approximately 30% from the 645.94 Wh of total energy consumption, where the consumption of real useful energy is 4% of this total.


In this paper, we have study the characterizations of submaximal spaces and extremally disconnected spaces via operation in soft topological spaces.


Anther Dehiscence.e-A study was begun in 1901 in connection with an article on the pollination of Solanum and Cassia, published in the Kansas Univerqsity Science Bulletin, and continued in 1903 in a thesis presented to the faculty of Washington University for the degree of doctor of philosophy. The author recognizes seven types of apically clehiscent anthers and designates them as araceous, gramineous,. polygalaceous, ericaceous, dilleniaceous, Solanum-Cassia, and melastomnataceous. First, these types are defined and the families and genera representative of each are indicated. Then there follows an account of the floral ecology of the forms, except of the first four types. Seven tables give the results of the arrangement of the data relating to the geographical distribution of the genera of the several types, and one shows the distribution of the flowering plants in general. Fourteen geographical regions are recognized, based on the floristic regions of Drude. The Tropical American Region shows a maximum of Phanerogamia, the Indian Region being second. The dilleniaceous, Solanum-Cassia, and melastomataceous types have the corolla, or at least the limb, widely patent, and the anthers basifixed and usually linear. In the dilleniaceous type the stamens are indefinite, the anthers usually elongate, the flowers usually actinomorphic and highly colored. To this type are assigned 16 genera belonging to 6 families: five genera of Dilleniaceve, five of ElTocarpacew-, three of Ochnaceve, one each of Theaceve, Bixace-e, and Flacourtiace-. An Indian maximum is indicated for this type, the Tropical American and Australian Regions being next with the same number of genera; the Tropical American Region, however, shows more species than the Australian. As visitors there have been observed: bees Xylocopa, Euglossa, Bombus, Apis, 1IMelipona, Halictus, Centris, Podalirius; birds a brushtongued paroquet, Charmosyna, a honey-sucker, Myzomela; flies


The dimensions of the maxillary and mandibular dental arches were measured from 280 subjects aged between 3 and 15 years in a cross-sectional study. The growth changes were examined by means of canonical analysis, a multivariate technique. This technique enabled the dental arches to be treated as biological units, rather than a series of discrete parameters, as is possible using univariate techniques. The results showed that the size and shape of the dental arches changed maximally between the periods 5–7 and 11–13 years of age. These periods correspond to the major phases of permanent tooth eruption.


The paper portrays three aspects of urban dispersion: urban structure, residents' location and land-use preferences, and social ecology. To explain the dynamic inherent in this form of urbanisation, it suggests an explanatory model concentrating on shifts in the respective importance of space, place and proximity associated with the passage from traditional monocentric to dispersed urban form. The paper draws its empirical substance from the Kitchener Census Metropolitan Area, one of the most dispersed metropolitan regions in Canada. The Kitchener case study highlights the defining characteristics of a dispersed urban structure: high automobile dependence, a scattering of origins and destinations, and a resulting absence of pronounced accessibility gradients. The paper also reports the results of a survey which indicates a harmonisation of residents' preferences with the main features of dispersion. The case study ends by mapping the residential location patterns of two groups with a disproportionate influence on new urban development: high income households and families with children. Their concentric distribution is consistent with survey results. In the light of the prevailing transport-land-use relation and of residents' location choices and expressed preferences, the paper foresees a further entrenchment of the dispersed urban structure. The paper closes by explaining the limited success of most intensification policies and by exploring the possibility of injecting more diversity into the dispersed landscape in order to accommodate a growing variety of lifestyles.


This manuscript reports the solution and micellar be haviour of an antibiotic drug Clindamycine Phosphate (CLN) in aqueous media. Surface tension and specific conductivity were used to find the critical micelle concentration (CMC) and in this way its surface and thermodynamic parameters were calculated. The electrical conductivity was measured as a function of concentration at various temperatures and CMC was calculated in the temperature range of 20 -50°C. Thermodynamic parameters i.e. standard free energy of micellization, o m G Δ standard enthalpy of micellization, o m H Δ and standard entropy of micellization, o S Δ were


Part 1 Protozoal diseases: malaria visceral leishmaniasis cutaneous leishmaniasis African trypanosomiasis American trypanosomiasis amoebiasis giardiasis cryptosporidiosis. Part 2 Helminthiases: ascariasis tapeworms (cestodes) filariasis and onchocerciasis human fluke infections. Part 3 Bacterial diseases: tuberculosis leprosy leptospirosis and relapsing fever acute bacterial meningitis enteric fever tetanus sexually transmitted diseases brucellosis and melioidosis anthrax, tularaemia and plague rickettsial diseases. Part 4 Diarrhoeal diseases. Part 5 Viral diseases: arboviruses Acquired Immunodeficiency Syndrome hepatitis rabies. Part 6 Fungal infections skin ulcers myiasis. Part 7 Nutritional diseases and poisoning: nutritional deficiencies snake bite. Part 8 Eosinophilia and unexplained fever eosinophilia pyrexia of unknown origin. Part 9 Travelling to the tropics: immunization and protection of the traveller.


John Courtney Murray's impact on the thought of religious freedom in the Church not only in the United States but the universal church can hardly be exaggerated. His influence can be seen in Vatican II's Dignitatis Humanae and on the later thought of John Paul II and Benedict XVI's affirmations of Murray's insistence on religious liberty. His legacy is twofold: first, that any Catholic theologian must presuppose the inviolable right to religious freedom before discussing religion and the public life, and second, that the Church has gained a more respected voice in the arena of justice, human rights, and public morality.


Abstract This commentary expands upon Eaton et al.'s research note about the challenges of measuring sense of place (SOP). Our body of work includes qualitative and quantitative research that supports their finding that landowners have a strong SOP and conservation ethic about their working lands. However, we deliberate on the importance of considering a broader interpretation of "economic dependence" in the context of SOP, which may include financial and non-financial benefits to the landowner. Eaton et al. report mixed results in its predictive power for conservation decisions on working lands. Yet, several issues negatively impacting economic dependence may override conservation management decisions and explain the "mixed" results reported by the authors. We posit that the definition of economic dependence should include both income and wealth generation as well as landowner amenity rents (defined as the landowner's internally derived benefits or satisfaction from the amenities on their working lands).


【Objective】The paper aimed to study dry matter accumulation dynamics and nutrient absorption under film mulch with drip irrigation.【Method】 Rice T-04 was used as experimental material and Logistic equation regression analysis was applied to study N rate effects on dry matter accumulation dynamics and nutrient absorption under film mulch with drip irrigation.Five N application levels(0,210,300,390,480 kg/hm2) was designed for the study.【Result】 The result showed that dry matter and nutrient absorption dynamic could be described by Logistic equation,accelerated accumulation period of rice dry matter and N,P,K uptake was at 66.7-99.5 d,56.0-88.1d,68.9-105.2 d,61.6-95.6 d after seedlings emergence,respectively.With the increase of N dosage,the maximum accumulation amount and the maximum rates of dry matter and N,P,K were gradually increased,while the accelerated accumulation period was slowly reduced.The same rhythmicity of dry matter and N,P,K was showed from the beginning to the end: the accelerated accumulation period of N was the earliest,K was the second,dry matter was the third and P was the latest.N dosage of 390 kg/hm2 showed the largest accumulation rates of dry matter and N,P and K.It was suggested that overuse of was not helpful to rice growth and nutrition uptake.Compared with flood irrigation treatment,the largest accumulation rates of rice under film mulch with drip irrigation was significantly bigger.The accelerated accumulation period was shorter than film mulch with drip irrigation,but there were no significant differences of P and K between the two cultivation modes.


Background: Asthma is a chronic inflammatory air-way disease with increasing prevalence rate during the recent years. There are studies about the relationship between asthma and infectious diseases, including the association between asthma and Helicobacter pylori. According to the latest studies, there is an epidemiological correlation between asthma prevalence and prevalence of H. pylori. Objectives: The aim of this research was to study the correlation between H. pylori and asthma by biopsy in five to eighteen year-old children who had undergone endoscopy at Shahid Beheshti Hospital. Patients and Methods: Three hundred children (5 to 18 years old) undergoing endoscopy owing to gastro-intestinal problems at Shahid Beheshti Hospital were observed for childhood asthma using the Gina 2010 questionnaire which included 24 questions with "yes" and "no" answers to identify asthmatic patients with five positive answers. Next, the patients were referred to an allergy and asthma specialist for clinical examinations, spirometry and post bronchodilator test (Post BD). Results: Among 138 H. pylori positive patients, eight cases (5.8 %) were asthmatic while of the 162 H. pylori negative patients 28 (17.3%) were asthmatic. This difference was statistically significant (P Value = 0.002). The correlation between H. pylori and asthma was studied after controlling the confounding variables including, gender, age and family history. The results obtained for the above-mentioned variables were significant (P Values of 0.004, 0.005 and 0.002, and Odd-Ratio Mantel Haenszel (ORMH) of 3.38, 3.24 and 4.06, respectively). Conclusions: Our findings showed that there is an inverse correlation between H. pylori and asthma. Performing more studies with larger sample sizes is necessary to confirm these results.


Background: Treatment of warts represents a continuing challenge for dermatologists as many of the available therapeutic modalities are associated with unsatisfactory results and high recurrence rates. Several clinical trials have proved the efficacy of intralesional immunotherapy by different antigens including MMR vaccine in the treatment of different types of warts. Methods: Total 150 patients having common warts over hands and feet including palmar and plantar warts were included in the study and were randomly divided into two groups. Group 1 consisted of 87 patients in whom MMR vaccine was given intralesionally in the largest wart whereas in Group 2, 63 patients were applied 100% trichloroacetic acid locally to the warts. These treatments were repeated 2 weekly for total three treatments. Patients were assessed for treatment response monthly for 3 months. Results: A highly significant difference was found in the response rates between the two groups (p 75% improvement and 26.44% patients had complete resolution whereas in TCA group, 11.11 % had >75% improvement and 7.94% patients had complete resolution. In the MMR group, side effects included pain at the injection site 100%, flu like symptoms 1.15 %, post-inflammatory hyperpigmentation 1.15% and tenderness 1.15% whereas in the TCA group all patients experienced burning sensation and 2 (3.17%) patients had post-inflammatory hyperpigmentation. Conclusion: Intralesional MMR vaccine is an effective treatment for warts without any significant side effects.


(1) Earthquake Research Institute, The University of Tokyo, Tokyo, Japan, (2) Department of Mathematical Informatics, Graduate School of Information Science and Technology, The University of Tokyo, Tokyo, Japan, (3) Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan, (4) Presto, Japan Science and Technology Agency, Saitama, Japan


The hatch of Heterodera fici in fig root leachate, soil extract, and distilled water was investigated by incubating newly formed cysts of the nematode at 10, 15,20,25 or 30 0 The fig root leachate and temperatures greatly influenced the emergence or second stage juveniles, More than 85% or the eggs hatched altet' three weeks at 20 and 25°C, At 30°C, about 50% or the eggs hatched arter 4 weeks, but no juveniles emerged therealter. The hatching was slow at 15°C and reached 60% after 6 weeks, No hatch occurred at lO°C in fig root leachate, and at all temperatures in soil extract and in distilled water.


PROBLEM TO BE SOLVED: To accurately and automatically adjust an automobile door already assembled with a door pillar by positioning the door on a body with a positioning screw device, and automatically moving an eccentric coupling bolt according to tan eccentric device drive program at the time of adjusting the door position at each door closing process. SOLUTION: An eccentric coupling bolt 4 has adjustment ranges 7.1 and 7.2 respectively for a retracting pass and an adjusting pass. A door is positioned on the operation of a positioning screw device 9 at the time of the assembly thereof with a body. Also, the adjustment of the door position is made at each door closing/opening process. In this case, the eccentric coupling bolt 4 is first moved from the eccentric drive device 5, depending upon the adjustment range 7.1 for the retracting pass. Thereafter, the bolt 4 is further moved from the device 5, depending on the adjustment range 7.2 for the adjusting pass. Furthermore, the program of an electronic control device 6 sets out an intermediate part 7.3 for the smooth transition of the coupling bolt 4 between the adjustment ranges 7.1 and 7.2.


become of major research interest to the survival of the species with a single gene such as Sirt 1 defective and involved with nutrigenomic diet treatment in global populations


ABSTRACT In times of crisis, governments can resort to tax rises and emergency taxation schemes to finance extraordinary needs. These schemes often generate tensions in the fiscal contract between the state and society, as they affect basic definitions regarding who is taxed, for how much, and what for. In the context of developing economies, where available sources of extraordinary rents are limited, dealing with these tensions can be problematic as it involves reconciling questions of fiscal legitimacy with the interests of influential economic sectors. This article analyses these tensions by exploring the case of Argentina in the aftermath of the 2001 debt default crisis, when emergency taxes on agricultural exports were implemented and then expanded under Kirchnerist administrations pursuing a 'post-neoliberal' developmental agenda. However, we argue that the government failed in legitimating this fiscal agreement, resulting in a tax rebellion by the rural sector in 2008 followed by the growing polarisation of the policy in partisan terms. By bringing to the fore the challenges and conflicts involved in legitimating tax collection, the article illuminates an overlooked aspect of the political economy of developmental states, particularly those seeking to enhance state autonomy while pursuing redistributive goals.


Choanal atresia is a rare congenital anomaly involving unilateral or bilateral posterior nasal choanal obstruction. Multiple associated anomalies have been described. We describe the case of a 1-month-old boy with bilateral choanal atresia, misdiagnosed after CT as a midline meningocele because the floor of the midline anterior cranial fossa was not ossified and secretion had accumulated in the obstructed posterior nasal choana.


The present invention relates to a composition for dyeing keratin fibers, comprising: - at least one oxidation dye chosen from oxidation bases pyrazolones; - At least one fatty alcohol nonionic polyoxyalkylene ether of formula (I) R- (O-Alk) -OR '(i); formula (I) wherein: o R denotes a hydrocarbon radical, linear or branched, saturated or unsaturated C -C, o R 'denotes a hydrocarbon radical, linear or branched, saturated or unsaturated C -C which may be substituted with a hydroxyl radical, it is an integer between 1 and 100 inclusive; o and Alk represents a (C -C) alkylene, linear or branched, preferably linear, such as ethylene or propylene, preferably ethylene; at least one chemical oxidizing agent. The present invention also relates to a process using this composition, as well as multi-compartment devices, suitable for the implementation of the invention.


EDRS Price MF-$0.65 HC-$3.29 Behavioral Objectives, *Course Descriptions, *Inservice Teacher Education, *International Education, *Latin American Culture, *Teacher Education, Units of Study (Subject Fields) This document represents the second phase of a three-phase project on international education and focuses on the study units which were prepared. It is also intended to serve as a guide to the preparation of materials and ways of developing an international dimension to education. The emphasis of the units is on the application of information as a guide to action. International education offers teachers an opportunity to assist students in the development of a broader repertoire of structuring processes. Two teaching strategies were employed--unit planning to present information in such a way that the parts form an interrelated and interdependent whole, and the use of written behavioral objectives to provide teachers with an opportunity to determine learning goals clearly. The construction of objectives is explained in detail, as is the selection of content for the teaching unit. Various kinds of direct and indirect learning experiences are considered, and methods of evaluation based on the use of the behavioral objectives. Six sample units are included: 1) "Vocational Agriculture," 2) "Argentina: The Land and the People," 3) "Physical Education Rhythms," 4) "Our Mexican Neighbors," 5) "World Literature," and 6) "Indians of Central America." (Related document is ED 038 349.) (MBM) A Guide for In-Service Programs in International Education by Paul G. Orr, Dean College of Education University of Alabama Vito Perrone, Dean New College University of North Dakota C. Roland Terrell Curriculum Study and Research University of Alabama College of Education. University of Alabama November, 1969 U.S. DEPARTMENT OF HEALTH, EDUCATION & WELFARE OFFICE OF EDUCATION THIS DOCUMENT HAS BEEN REPRODUCED EXACTLY AS RECEIVED FROM THE PERSON OR ORGANIZATION ORIGINATING IT. POINTS OF VIEW OR OPINIONS STATED DO NOT NECESSARILY REPRESENT OFFICIAL OFFICE OF EDUCATION POSITION OR POLICY.


Richardson's account of drives and valuation, and Maudemarie Clark's work on the self. In places, however, the central thread of the book is lost, and it's unclear how the arguments within and between chapters are to constitute a larger whole. Katsafanas does well to relate more technical discussions to broader themes in Nietzsche's thought, such as his mobilization of Nietzsche's account of bad conscience in Katsafanas' discussion of the falsifying effect of consciousness, but such productive exposition is rare. Cursory introductory and concluding chapters relate Nietzsche's theses to wider debates in moral psychology and the history of philosophy, but these concerns are noticeably absent from the heart of the book. Schopenhauer looms very large, as he should in any discussion of Nietzsche, but the use to which he is put is sometimes unsatisfying. It is difficult for any reader of Nietzsche to impress upon his scattered remarks the imprint of a system; since Katsafanas means to do just that, he too often appeals to Schopenhauer, on, say, the nature of drives, to fill in the blanks of Nietzsche's thinking, without establishing that Nietzsche was in fact influenced by Schopenhauer on this specific point or to this specific extent. In his discussions of willing and freedom, Katsafanas returns often to Nietzsche's figure of the sovereign individual who, unlike his weak-willed contemporaries, can rightfully claim the capacity to promise. Katsafanas mentions but does not seriously engage debates concerning Nietzsche's ultimate view of the sovereign individual, a figure argued by some to be parodic. Such a view, if true, would be problematic for Katsafanas' interpretation. The heart of the book is a picture of Nietzschean moral psychology that avoids the false dichotomies of his predecessors. Inclinations are not burdensome to a rational creature, nor is reason a slave of the passions; instead, reason and sensibility are inextricably intertwined in a complex and shifting vortex of forces. We are not absolutely free, nor absolutely determined, but we are more and less autonomous, more and less able to shift the prevailing vortex of forces that constitutes us. We achieve freedom not by casting off the shackles of society in search of a pre-social self, nor by identifying our freedom with the progress of our culture and its institutions; instead, freedom is a negotiation between our rootedness and our individuality. The picture Katsafanas offers is compelling, well articulated, and well defended. The book adds to our understanding of several timely debates, and thus should be read by anyone interested in Nietzsche's moral psychology.


In modern conditions, it is interesting to study foresight as an effective tool for identifying new strategic scientific directions. Its purpose is to develop an algorithm for conducting qualitative expertise in the application of the foresight methods with the ability to integrate forecast estimates. Currently, the vast majority of research activities results do not contribute to the innovative development of the state. To solve this problem, it is necessary to ensure a stable systemic relationship between specific sectors of the economy and higher education. The algorithm is developed on the basis of a systematic approach to the foresight methods and the use of the methods of bibliometrics, scientometrics, patent analysis and forecasting. The results and conclusions of this study are: an algorithm has been developed for conducting qualitative examination of the results of scientific activities in order to increase its practical significance, in which the authors propose the foresight methods as the most optimal tool for choosing priority areas of science and technology. Putting this approach into practice will make it possible to increase the efficiency of the foresight methods by both reducing time costs, and rationally using monetary and human resources.


The antispasmodic activity attributed by the popular medicine in methanolic extracts of Sida rhombifolia (n.v. afata), Bacchar is articulate, Chenopodium ambrosioides (n.v.paico macho) and Conyza bonariensis (n.v. rama negra) collected in La Pampa, Argentina was verified. The essays consisted m take seried contrast radiography of mice previously administered with the extracts. The antispasmodic activities was evaluated observing the comparative progress of the radio-opaque gastrointestinal tract in animals treated with the extracts in relation to atropin treated animals and the control group. The effect of the extracts on the transit gastrointestinal was estimated determining the time in which the evacuation of the substance radio-opaque begins and the time of gastric emptying.substance through the We conclude that the extracts of Sida rhombifolia, Baccharis articulata, Chenopodium ambrosioides and Conyza bonariensis which develop in La Pampa exhibit antispasmodic effects. The different effects found on the time of gastric ernptying and the intestinal transit suggests different mechanisms and places of action


Preface One question frequently raised in discussions with colleagues from neighboring countries,and with European and American scholars who follow closely China's neighboring relations is,how does China define its relations with neighboring countries?Although as early as sixty years ago,the Chinese government already provided the answer of five principles of peaceful coexistence


According to the author, the term "ubiquitous computing" coined Mark Weiser to show the principles of human interaction with the environment endowed with signs of intelligence. This concept is basic in the description of the model of human interaction with the computer system, in which the user is surrounded by computing devices integrated into the everyday things of the environment. In contrast to virtual reality, where there is a virtual world that computer reflects for person - with ubiquitous computing computers are brought into the real world around the person. This world consists of many digital mini-assistants (intelligence environment). Thus, by ubiquitous computing understand computers in the human world, not the human world inside the computer.


The component based approach for robotics development has been proposed. In this approach, robots are divided into various robotics elements as components and those elements are combined to be a complete robotics system. RT middleware is also developing as a platform on which RT functional elements (RT components) run. Since RT middleware enables reuse and switch of RT components, it becomes possible to respond to various requirements from users by combination of RT components. And it also becomes possible to develop parts individually and make development projects smaller. In the result, each vendor can concentrate on parts and fields which they are specialized (Fig.1).


Sample scenes from the biennial convention of the Music Educators National Conference, St. Louis, Missouri, March 18-23, 1950. + No. 1-A "Lobby Sing" at Hotel Jefferson. It is the traditional and popular custom to gather in a hotel lobby at the close of a convention day and sing for the joy of it. + No. 2-The Sunday afternoon concert. Picture shows Charles C. Hirt directing the University of Southern California Madrigal Singers, who shared the program with the Berkshire Quartet of Indiana University, Bloomington. + Other pictures made at the convention are reproduced on the three pages following. .'l . , & ..?. ' ..::!:' ' '~i:: c0 't "ad


The thesis deals with assertiveness as a communication technology. The aim was to outline to specify and analyze the assertiveness, the importance of communication, to highlight the benefits and results that an acquisition of assertiveness skills. The paper also discusses the use of assertiveness in specific areas of interpersonal relations.


Causal analysis greatly affects the efficiency of decision-making. Scholars usually adopt SEM (Structural equation modeling) to establish a causal model in recent years. However, statistical data allow researchers to modify the model frequently to arrive at good model fitness, and SEM is often misapplied when the data are merely fitted to a SEM and the theory is then extended from the analytical result based on presumed hypotheses. The paper proposed SEM modified by DEMATEL (Decision making trial and evaluation laboratory) technique, taking causal model of web-advertising effects for example. Having revealed that the new model is the one that conforms to actual data and is better than initial model, the results confirm that the DEMATEL technique can be an efficient, complementary, and confident approach for reprioritization of the amended modes in a SEM model. DEMETAL provides another tool for examining the accuracy of researchers' initial hypotheses. A model may be revised based on the analysis result of the DEMATEL technique, and a better model may be acquired. In addition, the DEMATEL technique may offer reasonable bases for modification of SEM to avoid over fitting and the above-mentioned misuses. In addition, the most important factor affecting the web-advertising effects may be found via the modified model, which benefits the manager for making strategic marketing plans.


Since the end of the Cold War, European and East Asian states have developed a series of unique trans-boundary structures and agreements, such as the European Union and ASEAN, and through new bilateral, multilateral and inter-regional relationships both Europe and East Asia are helping to transform other regions and the global community. This publication examines the complex emergence of a multi-level global governance system through innovative developments in info-communications governance; the role of policy advisors, think-tanks and related track-2 processes; and changes in higher education systems.


With the depletion of fossil fuel resources, as well as increasing global temperatures, the interest in sustainable energy is on the rise. Currently, cars are a significant source of harmful emissions due to the use of internal combustion engines. Incomplete combustion byproducts are extremely harmful to the environment and the population, with links to acid rain, smog, and respiratory issues. While green energy solutions, such as electric vehicles, are being developed, the treatment of exhaust can also be an effective way to reduce the release of emissions into the atmosphere. It has been shown that a solid oxide fuel cell (SOFC) is able to break down emissions, even exceeding the capability of typical exhaust treatment methods. An investigation into the usage of an SOFC as an exhaust treatment material has found that the amplification of a signal generated across the cell has an even greater effect on emission reduction.
 Here, the addition of cesium lead bromide (CsPbBr3) nanocrystals to the fuel cell is being investigated. The SOFC is tested as an exhaust treatment solution and as a power generation device in comparison to a typical SOFC without added CsPbBr3 nanocrystals. CsPbBr3 is a perovskite semiconductor, so it is expected to have an effect on the reactivity of the fuel cell. Investigating the effects of adding nanocrystals into a SOFC will lead to advancements in exhaust treatment systems as well as power generation systems. The work here will show a direct relationship between the quantity of nanocrystals contained in the SOFC to the emission reduction and power generation abilities of the SOFC.


Background: The current study, conducted at Department of Anesthesia, Rajiv Gandhi Institute of Medical Sciences, (RIMS), Adilabad, Telangana, India compared the efficacy of intravenous Ondansetron and granisetron in preventing postoperative nausea and vomiting in patients undergoing laparocscopic surgeries under general anaesthesia between September 2021 to August 2022. Materials and Methods: 100 ASA grade I and II patients undergoing laparoscopic surgery under general anaesthesia were allocated into two groups of 50 each. Before induction, group O took 4mg Ondansetron and group G received 1mg granisetron. CHI square test and student's unpaired t-test were used to analyse observations. Result: Both groups had similar demographics (age, age-gender distribution, weight, weight-gender distribution, and mean surgery length). Heart rate, systolic, diastolic, and mean arterial pressure were similar between groups. 36% reported nausea. Conclusion: In Group O and Group Gwhich was low. Group O had 22% retching and Group G 2%. Group O (16%) had more vomiting than Group G (2%) PONV was less common in group G (12%) than group O(36%). Group O (20%) required more antiemetics than group G (2%). Both groups had no side effects. In Group O, 12% of patients had headaches, while in Group G, 4% did. One patient in Group O had dizziness, although these were not serious adverse effects.


In this paper an implementation of unified intelligent controller methods for voltage controlled PWM driven three phase Induction Motor drive system has been developed and analyzed in detail. The Induction motor drive system involve dynamic d-q model in synchronously rotating frame. The performance of proportional controller (PI), Fuzzy and Artificial Neural Networks (ANN) has been investigated through MATLAB/Simulink environment. Finally the results are compared and validate that ANN is predictable, greater and give better responses than Fuzzy and PI controllers.


This review essay investigates the biological and physiological consequences of ptsd to deepen its academic understanding, alongside an analysis of psychobiological testing and assessment procedures. Psychological responses to traumatic events can be acute stress reactions or stress disorders. One among them is post-traumatic stress disorder (ptsd). When people experience a traumatic event, such as death, terror, or physical injury, they tend to demonstrate fear, helplessness, or hopelessness. Patients displaying other symptoms like re-experiencing the trauma, avoidance, or hyper-arousal also indicate ptsd. Experiencing extended ptsd may cause significant health problems, whether biological, such as the dysfunction of stress-responsive neurobiological systems, or physiological, such as hypertension and heart disease. Previous studies of trauma survivors reported a strong link between physical and mental health. The cumulative literature in psychology shows that traumatic exposure can cause disturbing effects in the short and long term. This review will contribute to developing an understanding of the biological markers of ptsd. This paper specifically deals with biological and physiological testing and assessment of ptsd. It includes widely utilized biological assessments and summarizes a general multi-model assessment to identify ptsd symptoms.


Objective To investigate and analyze the epidemy of hepatic diseases of employees in the economic and technical developing zone. Methods 1 638 samples were examined for serum HBV antigen and antibody by the ELISA. And liver and gallbladder type B ultrasonic examination were done on 242 of them . Results Positive rate of HBsAg was 9.83%, the male being 10.97%and the female being 5.93%. Abnormal ALT rate was 4.88%, in which 71.25%had no specific causes. The total hepatic disease morbidity was found to be 16.94%by the ultrasonic examination(that of fatty liver being 12.4%, liver cyst 0.83%, liver and biliary stone 1.65%, cholecystitis 1.24%), significantly different from HBsAg positive rate (P 0.001). Conclusion The hepatic diseases morbidity was high among the employees in the enterprises, demanding a better countermeasures against the diseases.


This study explored the reliability and validity of the Differential Aptitude Test—Form K (DAT-K) in a sample of 75 learners (mean age = 17.1 years, SD = 1.13) from a previously disadvantaged school in Johannesburg. Adequate reliability coefficients were obtained but coefficients were higher for nonverbal than verbal subtests. Face validity was judged to be adequate but construct validity was questionable. All subtests correlated within cluster (verbal, non-verbal) but all the subtests with the exception of the Comparison subtest loaded highly on a single factor. Examination of the influence of language as a variable suggested that learners whose home language was an African language did significantly poorer on all the DAT-K subtests except for the Comparison subtest. These findings lend support to the arguments that psychological testing in South Africa is problematic particularly in individuals who do not speak English as their first language.


This paper describes the theory of the system for vehicle monitoring and management,theselection of communication link,and the idea of software and hardware design in the system.Thenone design scheme about vehicle monitoring and management system is provided.Finally,a practicalsample is given to show that the system is feasible and reasonable.


Background: The literature is relatively sparse on the epidemiological and histopathological profile of eyelid lesions in Rajasthan. The present study aims to characterize the histopathological profile of both non-neoplastic and neoplastic eyelid lesions from a tertiary care centre in Ajmer, Rajasthan. Methods: A total of 55 lesions with histopathology diagnosis were included. Inflammatory non neoplastic lesions were excluded (15.38%). The lesions were categorized into three groups according to the origin: epidermal, adnexal tumors and 'others', including melanocytic, vascular lesions and others. Result: Total 55 biopsy specimens were evaluated of which, 44 cases (80%) were benign, 10 cases (18.18%) were malignant and single case (1.81%) was pre malignant. The age distribution varied from 2-81 years with mean age of 36.75 years. Benign lesions were seen more commonly in young boys of first decade and malignant lesions were more frequent in adult females. Most common benign tumors included epidermal cyst (31.81%) followed by hemangioma (18.18%), squamous papilloma (9.09%). Six cases of adnexal tumors (9.23%) were also noted. The most frequent malignant tumor included Basal cell carcinoma (81.81%). Only single case of sebaceous gland carcinoma was seen. Conclusion: Eyelid lesions are diverse and vary in clinical presentation and prognosis. Early and accurate histopathological diagnosis of these lesions is essential for proper management and favorable prognosis.


Key words: quality, growth, model, leaf unfolding rate, internode, plant height, plant width, leaf area, temperature, plant spacing, season, light, development, image processing, grading, neural network, pot plant, Ficus benjamina 'Exotica'. The market is increasingly dictating the specifications for products. A well-defined marketable product must be delivered at a defined moment in time. A system was developed for growers to control development and growth of pot plants to achieve a defined quality on a specified delivery date. A theoretical framework of quality modelling used in the food industry was successfully implemented within the domain of pot plants. The visual quality of Ficus benjamina 'Exotica' was explained for 88.7% by four variables (in addition to the fixed plant height of 1.20 m.): the density of the leaf mass in front-view, 40-60 cm above pot rim; the width in side view, 40-60 cm above pot rim; the width in front-view, 0-20 and 20-40 cm above pot rim. Effect of temperature, plant density (control factors) and season (not controlled) on the growth and development of Ficus in relation to these quality features was quantified. Development of Ficus benjamina 'Exotica' showed a regular pattern. Plant height increased with temperature up to 29.5°C. The effect of plant density on this variable was small. Leaf unfolding rate was influenced by light and temperature, plant density was of minor influence. Its response to temperature showed an optimum at 30°C. The final internode length was mainly affected by light intensity, temperature had no effect. The width of the plant and the density of leaf mass increased at lower plant densities. The effect of temperature on visual quality of Ficus was small. A simple model based on only two major quality features, plant height and plant width, was developed and could successfully control visual quality of Ficus . Plant height as a function of plastochron age and internode length in relation to temperature and light was adequately predicted. Plant width was successfully controlled by spacing operations, using image processing to monitor this crop feature. By integration of four functional modules, a model for visual quality, a crop growth control model, image processing to monitor crop development and a neural network to grade plants, a crop quality control system (CQCS) was obtained and successfully implemented. This system was compared to other systems and its limitations and transferability to other crops was discussed. Furthermore, the system was evaluated for commercial practice.


This paper describes the derivation of a Knowledge-Based Potential for intermolecular interactions from the statistical information stored in the Cambridge Structural Database. We develop a statistical mechanical method that relates the occurrences of intermolecular contacts in the database to their energies. Our approach allows us to quantify (in the form of energy) the geometrical preferences of interactions. We use our method to construct energy maps for a hydrogen bond between carbonyl oxygen and amino hydrogen. Our results demonstrate high orientational selectivity of this type of hydrogen bonding.


Cu(II) is one of the pollutants that is exist in the produced wastewater by many industries. According to the World Health Organization (WHO), its concentration should be less than 2 mg/L. In this study, Phosphorus slag (PS) and ground granulated blast-furnace slag (GGBFS) as industrial wastes with the properties of abundant and low cost are used to remove Cu(II). The effects of shaker rotation rate, initial concentration of Cu(II), and amount of adsorbent on the adsorption process are investigated. The adsorption capacity was maximized at a shaking rate of 150 rpm, initial concentration of 50 mg/L, 0.2 g GGBFS per 0.03 liter, and 0.5 g PS per 0.03 liter. At various temperatures, the values of thermodynamic parameters were calculated by measuring the equilibrium data. The results showed that the adsorption process was exothermic using both GGBFS and PS adsorbents. The experimental data of Cu(II) adsorption by GGBFS and PS was fitted well by Langmuir and Freundlich isotherm models, respectively. The maximum adsorption capacity were obtained 156.30 and 151.52 mg/g for GGBFS and PS, respectively. Also, the kinetic modeling indicated that the adsorption process is achieved to the equilibrium state using both adsorbents at less than 5 min.


The Far Eastern region in 1946s — 1960s passed through the recovery period of the transition from war to peace. The region was of strategic importance. The Soviet state made up for the shortage of labor resources in the Far East through forced migration, agricultural and industrial resettlement. The Far East experienced the progressive development of industry, agriculture, transport, construction, and the social sphere. In 1946—1960 became an important region of the country, which strengthened the position of the USSR in the Asia-Pacific region.


The present invention is directed to beverage compositions comprising a preservative system comprising cinnamic acid and at least one weak acid chosen from benzoic acid, sorbic acid, alkali metal salts of benzoic and/or sorbic acid, and mixtures thereof; at least one beverage component chosen from juices, sweeteners, and mixtures thereof; and water, wherein the composition has a pH ranging from about 2.4 to about 4.5, with the proviso that the composition does not comprise tea concentrates, extracts or powders.


The purpose of this study was to examine the entrepreneurship consciousness of the college students in Daejeon City. The following results were fund: First, the level of the entrepreneurship consciousness of the college students were very high. Second, the younger group tended to be more active in venturing during the college time. Third, the group over 23 years old tended to have higher level of the abilities as a man of enterprise. Fourth, students with the self-employed parents tended to be high level of entrepreneurship consciousness and their personal traits for the enterprise compared with other groups.


The aim of this note is to show that there are certain non analogical properties between the 1-function quantified predicates (or the sets definable by such predicates) in Kleene hierarchy with free variables of types _<1 and those with free variables of type 2. In particular, there is no second separation (and hence, reduction) result for the classes of sets definable by the 1-function quantified predicates in Kleene hierarchy with free variables of type 2, in contrast to the case with free variables of types _<1 in which the reduction theorem holds for the universal quantifier first sidenamely, using the notation of Addison's [1, for II sets (and hence, as to separation, the first and the second separation theorems hold for the existential quantifier first side namely, for sets). Throughout this paper, the ideas and the techniques of Kleene [8, in particular, 8.2-8.8J are used. 1o We assume familiarity with [5-8, and use the notation of them unless further references. Using the notation of 1 (in addition, with superscripts m--0, 1,2,... exhibiting the maximal type of free variables of the predicates), we denote by .', II' the classes of predicates (or sets) in Kleene hierarchies, sccording to the kind of the outermost quantifier, the highest type "r" of variables quantified, the number "k" of alternations of the quantifiers of type r and the highest type "m" of quantifier-free variables in the forms of Kleene's tables (cf. [6, (a) with free variables of types 0, p. 315 and [8, (c) p. 41), respectively. For example, a predicate P(a, , F) expressible in the form


Utilization of coastal plain area for farming are scarce due to the problems faced in the development of those lands such as low fertility, high percolation as well as evaporation rate. Temperature ranges from 40-60°C. In order to increase the utilization of the land, an attempt was done to study the effects of number of manure and irrigation rate on the yields and soil water extraction of maize, groundnut, tomato and chilly pepper in sandy soil. A series of experiment w as conducted from April to December 200I using completely randomized design. The treatments included 4 rates of manure i.e. 10, 15,20 and 25 MT/ha and 4 rates of irrigation I.e. 0.6 I/day, 0.9 I/day, 1.21/day and 1.5 I/day. The result of the experiment showed that the favourable condition to keep moisture content in sandy soil at field capacity and flushing of heat in the soil was achieved at irrigation rate of 1.2 I/day except for tomato which obtained the highest water extraction at irrigation rate of 0.9 I/day. Soil water extraction decreased between 0.15 to 0.55% when irrigation rate were reduced from 1.2 I/day to 0.9 I/day and 0.6 I/day on: maize, groundnut and chilly pepper. The highest yield was obtained at fertilization rate of 20 MT/ha except for maize which obtained the highest yield at fertilization rate of I0  MT/ha. Keywords: Coastal plain, Physical properties, Drip irrigation, Organic fertilizer


Here's a quick look at some common misconceptions that can lead to severe tubular goods damage caused by rust. Recommendations are given for correctly using thread compounds, thread protectors, coatings and inhibiting fluids.


Low acetic acid-producing strains were isolated from cerulenin-resistant mutants of the sake yeast K 7(Saccharomyces cerevisiae).Acetic acid is considered to be an intermediate metabolite of the cytosolic acetyl CoA synthetic pathway from acetaldehyde.Cytosolic acetyl CoA is used for the biosynthesis of sterols,fatty acids,etc.Cerulenin is an inhibitor of fatty acid synthase.Thus,a mutant producing lower levels of acetic acid and higher levels of acetyl CoA is supposed to show cerulenin resistance.Out of 80 cerulenin-resistant mutants,four were selected as low acetic acid-producing mutants using a fermentation test with a liquid synthetic medium and a small scale sake fermentation test.K 7 and one mutant,K 7-163,produced 136.6 mg/i and 16.4 mg/l of acetic acid,respectively,in pilot scale sake making.Three of the four mutants showed higher acetyl CoA synthetase(ACS)activity than K 7 during the late period of growth,which appeared to be the reason for their low acetic acid productivity.However,all four mutants showed multi-drug resistance,and/or high ethyl caproate productivity,which was probably caused by FAS 2 mutation.Thus,further studies are needed to confirm the relationship between low acetic acid productivity and cerulenin resistance.


Previous work from this department has shown that resistive tracheostomy filters increase the partial pressure of oxygen in capillary blood and also provide a significant amount of heat/moisture exchange. Until now it has not been shown whether there is any long‐term beneficial effect and in particular whether raised tissue oxygenation is maintained using a practical filter device.


A complete synthesis of I-O-hexadecyl-2-O-N-(heptadec-8-cis-enyl)carbamyl-sn-glycer0-3phosphocholine. a novel analog of phosphatidylcholine, has been described. Each step is simple to perform and gives the desired products in high yield. Also, some of the intermediates formed during the synthesis have been efficiently utilized to prepare 1-O-hexadecyl-2-O-oleyl-snglycero-3-phosphocholine, I-O-hexadecyl-2-oleoyl-sll-glycero-3-phosphocholine and 3-O-hexadecyl-2-oleoyl-sn-glycero-l-phosphocholine. These phosphatidy1choline (PC) analogs are useful for studying the possible role of phospholipases in the capture and lysis of liposomes in vivo.


Summary.  Although first proposed to be the primary regulator of platelet production 45 years ago, the gene for thrombopoietin was cloned only within the last decade. Since then, our understanding of megakaryocyte and platelet production has increased substantially, and it is now appreciated that in addition to its critical role in regulating thrombopoiesis, the hormone affects multiple aspects of hematopoiesis, including playing a non‐redundant role in stem cell survival, self‐renewal and expansion. In addition to this greater physiological understanding of thrombopoietin biology, the molecular mechanisms by which the hormone affects cell survival and proliferation are coming under increased scrutiny. At least four signaling pathways have been identified that play important and non‐overlapping roles in stem cell and megakaryocyte growth and development, potentially providing new strategies to therapeutically intervene in hematopoiesis. This review will focus on our current understanding of these processes.


The mouse genome carries one gene and two pseudogenes for cytoplasmic thymidine kinase. The overall structure of these genes was determined with the help of cosmids and lambda phage clones and the upstream sequence containing the promoter was determined. The data allow an allocation of bands seen in the complex patterns of genomic Southern blots obtained from the DNA of wild type cells and of thymidine kinase deficient mutants to the gene as well as to the two pseudogenes. The much used LTK cell line was found to lack the entire gene but to retain the pseudogenes. Two other TK cell lines had DNA patterns indistinguishable from the wild type. Whereas the LTK line did not produce any TKmRNAi the two other mutants had normal amounts of TKmRNA but no cytoplasmic TK activity. INTRODUCTION Thymidine kinase (TK)> an enzyme of the pyrimidine salvage pathway, catalyses the phosphorylation of thymidine to dTMP. There are two types of enzymes in mammalian cells, one is localized in the cytoplasm and responsible for the salvage of thymidine for nuclear DNA replication! the other one is confined to the mitochondria and is responsible for pyrimidine phosphorylation in the organelle (1,5,3). The activity of the cytoplasmic enzyme and the production of mature mRNA is strongly regulated with the growth condition of the cell. While the activity of this enzyme is very low in arrested cells, it increases in late Gl and early S phase of the cell cycle in growth stimulated cells (4,5); the quantity of mature mRNA for the enzyme parallels this behaviour (6«7,B,9). There is some evidence that the regulation of the production of stable mRNA in stimulated cells is, at least in part, posttranscriptional (8,10,11,15), however, there is still some controversy as to the © IRL Press Limited, Oxford, England. 1 8 Nucleic Acids Research contribution of transcriptional and posttranscriptional processes (13). Although this precise regulation of TK suggests an essential role for the enzyme, mutants lacking the cytoplasmic enzyme activity are readily isolated from .i variety of cell lines in culture. These TK mutants are selected by growth of cells in the presence of bromodeoxyuridine and they are characterized by their lack of growth in a medium (HAT) necessitating an active salvage pathway for the production of thymidine precursors for DNA replication (1). One of these mutants, the mouse LTK cell line, is widely used in celland molecular biology; if co-transfected with a TK gene (mostly from Herpes simplex virus) and any other gene, positively transfected cells can easily be isolated on HAT medium. In spite of their wide application! the molecular basis of the TK phenotype of these mutants is not known. Analyses of genomic DNA from wild type and mutant mouse cells by Southern transfer have yielded complex patterns (l't and unpublished observations from this laboratory) which did not allow a clear answer as to which parts of the gene are changed or lacking in LTK mutants. Clearly, this complex pattern is due to the presence in mouse DNA of pseudogenes for TK and it was therefore essential to clarify the structure of the gene and of the pseudogenes before definitive answers can be expected from the analysis of mutants. In this communication we describe the structure of the normal gene, of its promoter and of a pseudogene for TK present in the mouse genome. While this pseudogenes has all characteristics of a processed pseudogene there is a second one which has not yet been fully characterized but which seems to contain scrambled TK sequences. Together these three genomic sequences account for the bands seen in Southern blots and hence allow a clear answer in the analyses of TK mutants. MATERIALS AND METHODS Screening of a cosmid library A cosmid library, carrying mouse DNA fragments obtained by a partial S.a.y IIIA digest and inserted into pCos2EMBL was kindly provided by Anna-Maria Frischauf (ICRF, London). Clones containing TK sequences were isolated by hybridization with mouse TK cDNA (B) and purified. Three types of cosmids were analysed:


In this paper, I will explore basic properties of the group PSL(2,R). These include the relationship between isometries of H2, Möbius transformations, and matrix multiplication. In addition, this paper will explain a method of characterizing the aforementioned transformations by the trace of their matrices through looking at the number of xed points of a transformation.


ABSTRACT The aim of this study is to investigate the prevalence of discomfort after playing drumming games and to find more comfortable playing positions in order to reduce musculoskeletal disorder syndromes. A questionnaire was used to perform a survey of musculoskeletal symptoms in players of drumming games. The data were compared using the Chi-square test, and the factors of postures and positions in which stress was generated through wrist activity and their relationship with musculoskeletal disorder syndromes were investigated. This study consisted of two experimental study sessions; 37 subjects participated in the experiment session in 2007, 96 subjects in the 2008 session. For the 2007 study, the results show that posture is related to musculoskeletal disorders after playing drumming games and stress generated to beat the drums with or without wrist activity affects musculoskeletal disorders on the second day (p<0.05). In the 2008 study, the results show that posture is related to the subjects' feelings of discomfort. In these two studies, the results showed that the adoption of a standing posture while beating the drums causes the most serious musculoskeletal disorders of the four common postures, while a sitting posture using the wrist to beat the drums causes the least serious musculoskeletal disorders of the four common postures. Musculoskeletal symptoms differ according to the player's posture, and if the position is natural and relaxed, the incidence of musculoskeletal disorders is reduced.


Context-aware Recommender Systems aim to provide users with the most adequate recommendations for their current situation. However, an exact context obtained from a user could be too specific and may not have enough data for accurate rating prediction. This is known as the data sparsity problem. Moreover, often user preference representation depends on the domain or the specific recommendation approach used. Therefore, a big effort is required to change the method used. In this paper we present a new approach for contextual pre-filtering (i.e. using the current context to select a relevant subset of data). Our approach can be used with existing recommendation algorithms. It is based on two ontologies: Recommender System Context ontology, which represents the context, and Contextual Ontological User Profile ontology, which represents user preferences. We evaluated our approach through an offline study which showed that when used with well-known recommendation algorithms it can significantly improve the accuracy of prediction.


Ru-catalyzed heterocyclization of alkynyl substituted anilines, benzamides, and benzylamines yields the title heterocycles (II), (IV) and (VI), resp., under mild conditions.


ABSTRACT This article discusses a survey distributed to photojournalism professionals in order to determine their metadata preferences for photograph retrieval in an online archival system. Their top preferences included: named objects, specific events occurring in the photograph, browsing, and photographer-supplied keywords. Findings included problems with news photographers' metadata quality as well as librarians' inability to supply all the necessary metadata in this context. Additionally, it was found that current controlled vocabulary methods are not useful for the photojournalists' setting. New approaches to better facilitate search and retrieval of news photographs are suggested.


A graph grammar is described that can be used to replicate arbitrarily labeled strands of particles (modeled as linear graphs). The rules of the grammar dictate how pairs of particles should attach or disassociate upon random collisions, and thus describes a parallel and completely distributed algorithm for replication. The correctness of the algorithm is proved and the rate at which replication occurs is characterized. The algorithm may be applied to systems of programmable parts (stirred or agitated in a fluid) that can encode the (very simple) rules of the grammar and that can attach and dis-attach to create strands and other structures.


In view of problems of low precision,low sampling rate and low data transmission rate existed in current data collection products based on USB interface in China,a data collection card with high performance and low noise was designed.The card uses high-speed differential amplifier AD8132 to make preamplifier;uses CPLD and SRAM to compose large capacity FIFO;uses USB2.0 bus technology to transmit data;uses independent clock to provide accurate synchronous clock signal for CPLD and AD converter to reduce clock phase noise;uses VC++ to design application program of upper computer to realize data analysis and processing.The test result showed that the card has advantages of low noise,rapid transmission rate and high precision.


Nowadays, human identifications are necessary for our routine activities such as entering any secure locations besides many other applications. To that end, higher security levels need with easier user interaction which can be achieved using bio-metric verification. Bio-metric verification helps us identify people based on their extracted physical or behavioural features. These features should have certain properties such as uniqueness, permanence, acceptability, collectability, and the cost to employ any bio-metric. HSV is one of the bio-metric verification which authenticates whether the signature is genuine or forged. In our study a new approach is proposed for online signature verification using classifier model and comparing techniques. The classifier model i.e., GMM is used to extract the physical and behaviour features. The comparison technique i.e., LCSS is used for comparing extracted features. The publicly available online handwritten signature data(MCYT-100 database) is used for experiments. The results obtained in the form of performance metric curves called FAR, FAR, EER, ROC curves. To know the performance of the verification system, it is compared with the widely used comparing technique called Dynamic TimeWarping. Our experiments show that GMM with the LCSS authenticate persons very reliably and with a performance better and matching with best comparing technique, DTW.


The techniques involved in using indirect immunoelectron microscopy to detect iso- and auto-antibodies of human spermatozoa are described. Sensitized red cells viruses ferritin and peroxidase are labels used for either scanning or transmission electronmicroscopy (EM). Combination of EM with techniques of colloid physical chemistry and physics can measure the surface charges of human sperm; this technique is briefly described. Freeze-etching and fracturing can be used to study sperm membranes and the acrosome. The techniques available to study the chemical nature of organelles and the ultrastructure of fibrils of the flagellar filament are mentioned.


ABSTRACT Aim: Previous research found that UCA1, a long non-coding RNA, aberrantly expressed and associated with cell proliferation and chemo-resistance in many cancers. The aim of this study was to investigate the role of UCA1 in acquired resistance of EGFR-TKIs in NSCLC. Methods: UCA1 expression level was detected by quantitative reverse transcription polymerase chain reaction (qRT-PCR) in NSCLC cell lines or tumor tissues. Si-RNA was used to downregulate the expression of UCA1. The effect of UCA1 on cell proliferation and apoptosis was undergone by CCK-8 and flow cytometry assays. The expression of proteins was determined by western blot and immunohistochemistry (IHC) analysis. The gefitinib-resistant PC9/R xenograft tumor models were used to validate the effect of UCA1 in vivo. Results: UCA1 was significantly up-regulated in gefitinib-resistant cells PC9/R and H1975 compared with gefitinib-sensitive PC9 cells. By silencing UCA1, the gefitinib sensitivity was partly restored in PC9/R,but this change in sensitivity was not observed in H1975. Inhibiting UCA1 induced cell apoptosis in PC9/R, and significantly restrained tumor growth in nude mice, compared with control group (P Conclusions: UCA1 could regulate cell proliferation and apoptosis through activating PI3K/AKT/mTOR pathway, and its over-expression was associated with acquired resistance of EGFR-TKIs both in cell lines and clinical samples, which suggest that UCA1 might be act as a biomarker to predict the acquired resistance of EGFR-TKIs. Disclosure: All authors have declared no conflicts of interest.


We report on novel excitation properties in the \ensuremath{\nu} $=$ 2/3 bilayer quantum Hall (QH) phases by carrying out magnetotransport measurements using a GaAs$/$AlGaAs double-quantum-well sample. We refer to the areas with different particular excitation properties in a single phase as phase internal areas (pi-areas). The differences of the excited states between the pi-areas in the high- and low-magnetic-field region of the same phase lead to different behavior of thermal activation energy \ensuremath{\Delta} under a tilted magnetic field. A new pi-area appears between the balanced point and the single-layer region when \ensuremath{\Delta}${}_{\mathrm{SAS}}$ is small. A simple theoretical model based on the composite-fermion picture is advanced for bilayer fractional QH systems to interpret the characteristics of these pi-areas. Finite-size exact-diagonalization calculations are also executed to verify the validity of the theoretical model.


In this paper, we consider the tachyonic instability of Kerr-Newman (KN) black holes in the Einstein-Maxwell-scalar (EMS) theory with nonminimal negative scalar coupling to Maxwell term, and then obtain a bound $(\frac{a}{r_+}\geq0.4142)$ for spin parameter $a$ of KN black hole in the limit of coupling constant $\alpha\rightarrow-\infty$ by using analytical method. In addition, we perform a $(2+1)$-dimensional time evolution of linearized scalar field perturbation on the KN black hole background by implementing the hyperboloidal foliation method numerically in the EMS theory. It recovers the \textit{spontaneous scalarization} phenomenon for KN black hole in some certain regions of the parameter spaces. We further plot corresponding threshold curves $\alpha(a)$ which describe a boundary between bald KN black holes and scalarized spinning black holes in the EMS theory.


We have mutated several amino acids in the region of the GABAA receptor α1 subunit predicted to form a small extracellular loop between transmembrane domains two and three to investigate its possible role in ligand sensitivity. The mutations were S275T, L276A, P277A, V279A, A280S and Y281F. Mutant α1 subunits were co‐expressed with β2 and γ2 subunits in tsA201 cells or Xenopus oocytes. Binding studies revealed that the only mutation that significantly affected [3H]Ro15–4513 binding was the V279A substitution which reduced the affinity for this ligand. Electrophysiological examination of mutant receptors revealed that L276A, P277A and V279A displayed rightward shifts of their GABA concentration‐response curves, the largest occurring with the L276A mutant. The impact of these mutations on allosteric modulation by benzodiazepine‐site ligands was examined. V279A reduced the potency of both flunitrazepam and Ro15–4513 but, in each case, their efficacy was enhanced. A280S resulted in a decrease in flunitrazepam efficacy without affecting its potency. Additionally, P277A and A280S resulted in Ro15–4513 losing its inverse agonist effect at these receptors. These results suggest that a domain within this small extracellular loop between TMII–TMIII plays a role in determining the sensitivity of GABAA receptors to both GABA and benzodiazepine‐site ligands.


Four features of the uremic syndrome have been implicated as the cause of the skeletal changes which invariably occur in patients with prolonged chronic renal failure: metabolic acidosis,1,2retention of phosphate (and other ions), functional vitamin D deficiency,3and secondary hyperparathyroidism.4Yet, despite extensive investigation we are still unsure about the ultimate causes of renal osteodystrophy and are equally uncertain whether the skeletal response to chronic renal failure is detrimental or whether it represents evidence of a set of compensatory adjustments without which the patient would be even more threatened. In this communication, we shall review the evidence bearing on these questions which we have accumulated from our studies of bone cell metabolism in vitro. First, we will report the distortions of normal bone cell metabolic patterns observed in biopsy samples taken from 11 uremic patients and show how these patterns resemble those found in patients with


The study of harmonious person from the perspective of harmonious society is a brand-new topic,and its basic category,theoretical framework,significance and construction are all in exploration.The theory clue of the paper is that the person is the ontological foundation of the society as well as the person's existence method.The paper takes the socialism harmonious society as the practical starting point,makes efforts in constructing the theory system which includes the connotation,denotation and significance,and ends with construction of the harmonious person and the relationship between harmonious person and harmonious society.Its discussion centres on three theory themes of "what is the harmonious person","how to construct the harmonious person","relationship between harmonious person and harmonious society".


The utility model discloses a mechanical part connection element, and provides a double-end stud. The double-end stud comprises a connection rod, a short screw and a long screw, wherein the short screw and the long screw are arranged at the two ends of the connection rod and are connected with the connection rod integrally. The head portion of the short screw is provided with a pressing rod. When the short screw provided with the pressing rod on the head portion is screwed into a body thread hole for an enough screwing length and the threaded root portion of the short screw is not screwed into the body thread hole, the pressing rod abuts against the bottom of the body thread hole firstly, and then the double-end stud is fixed to a body with the dependence on pressing force of the pressing rod and the bottom of the main thread hole.


The Objective Yield Survey is a series of monthly measurements conducted by the United States Department of Agriculture (USDA) National Agricultural Statistics Service (NASS) during the growing season for the purpose of forecasting end-of-season yield for crops such as corn, soybeans and wheat. In this paper, we discuss models for corn using data from the state of Iowa during the years 1979 to 1985. Thorough discussions of the survey design and current forecast methods can be found in Francisco, Fuller and Fecso (1987), and Reiser, Fecso and Taylor (1987), respectively. An abbreviated description follows. An early season estimate for the number of acres planted or to be planted to corn is calculated by NASS from data collected during the June Enumerative Survey, a multistage stratified area sample. Objective Yield Surveys are conducted during the months of July through November, using fields that are subsampled from those visited during the June Enumerative Survey. In Iowa, approximately 240 fields are selected each year. For each selected field, a pair of randomly located units is established for data collection. Each unit is two rows (of corn) wide and fifteen feet long. In early July (month number one for the Objective Yield Survey), one half of the selected fields are visited, and data pertaining to number of stalks in each unit are collected. Starting in August (month two), all selected fields are visited monthly until the crop is either harvested or fully mature. No fields are visited after November (month five). During the visits in months two through five, data is collected on both number of ears and size of ears. Although 240 units are selected for the sample each year, some units are lost to refusals by owners, changes from intentions to plant as stated in June, and damage to crops. As a result, data is available each year on approximately 200 fields, or 200 pairs of units. For analysis purposes, each pair of units is treated as a single observation. Even though the data represent observations over time, the number of time points is small, and, in the past, the data has been treated as essentially cross sectional. That is, data from July are used to develop a July forecasting model, data from August are used to develop an August forecasting model, etc. Trends over months within years are not presently used in forecasting models. In this paper we consider the use of panel models, which incorporate aspects of both cross sectional and time series data. Panel models are heavily used in the social


Science centres all over the world are making huge efforts to increase the public understanding of science and capacity to solve problems in creative ways by the means of technology. The free-choice settings invite visitors to explore and experience science and technology through self-direction and self-discovery. Assessing the educational outcomes of the Science Centre pedagogy is not an easy task, but it may be fruitful to assume learning in technology in this setting to be an enculturating process. If so, the task is to summarize evidence of interactions that enculturate. In this paper I want to discuss my forthcoming thesis from this point of view. I regard the science centre exhibits to be artefacts, materializing the views on science/technology and communication/learning in the social practice of the science centre movement. Focus is on how teenagers reproduce this practice when interacting around and with the exhibits. I am using the methods of visual ethnography to analyse what happens in these encounters, and data consist partially of video documentations done by fifteen-year olds visiting a Swedish science centre. The main issue in this project is to move towards a more thorough understanding of the potentials, difficulties and consequences of putting science and technology on display and to try out new ways of doing research on learning in science and technology in free-choice learning settings.


The development of a data-tracking infrastructure for outpatient addiction medicine helped inform policy, improve practice, and measure impact at Geisinger.


In rural areas of Nepal and surrounding countries, earthquakes are common and often deadly. The World Bank has been collecting data over the past decade on school buildings in these areas in order to evaluate their structural integrity and determine the risk earthquakes pose to students in school. Originally the World Bank manually classified the data by studying photographs of the buildings and reporting structural features and overall integrity. Recently they have been attempting to replace this system with an automatic classifier which leverages computer vision techniques. This project attempts to improve the state of the World Bank's current automatic classifier by gathering additional training data from previously unused World Bank sources. This data is used to create a binary classifier that will work to classify the buildings that are input to the Global Library of School Infrastructure (GLOSI). In order to validate the results from this new binary classifier the School Safety team has created scripts that print out the accuracy, precision and F score of the model. This along with the GradCam platform will allow for better training in future scenarios. Introduction, Background, and Related Work


The construction of bipartite graphs is one of very important problems in the design of Tornado codes.Based on the advantages exhibited in the construction of bipartite graph in LDPC code with PEG algorithm,an improved PEG algorithm is presented.The simulation results show that the improved algorithm has a higher executive speed compared with the original PEG algorithm and the Tornado codes which constructed with this algorithm have a better performance.


The moralist Tao Xingzhi' s moral education theory is no wonder great treasure in our country' s history of education. It has reflected the conflict and integration of Chinese and Western culture. It has the sources of two respects: one is the introduction and transform of the western moral theory , the other is the inheritance of our country's outstanding traditional morals.


This is a report on the progress made in the first year of the CROSSCHECK project, a collaboration between NADA/KTH and Linguistics/SU on the development of a grammar checker for second language writers of Swedish, and the collection of a corpus of written learner Swedish. The CROSSCHECK grammar checker is based on the GRANSKA platform; hence, further development of GRANSKA forms a natural part of the project. We have implemented a server version of GRANSKA. GRANSKA is run continuously on the server, and therefore the scrutinizing tasks can be performed immediately without any tiresome initializing. Grammar checking of a web page now takes less than a second compared to half a minute before. We use PHP for the communication between the web page and the server. The rest of this report is structured as follows. In the next section, we report on our progress for the items (work packages) specified in the project work plan submitted with the original project application in October 2001. These are repeated here for convenience:


After forty years of tremendous advances, Laser wakefield acceleration (LWFA), in which an ultra-intense femtosecond laser interacts with a gas target to produce energetic electrons, is becoming more and more mature. Acceleration with a high repetition rate will be an important topic in the near future. When operating at a high repetition rate, the impact of the gas load on the vacuum system cannot be neglected. Among the widely used gas targets, gas cells have a lower flow rate compared to supersonic gas nozzles. However, most gas cells were several centimeters long, not suitable for a moderate-size laser facility. In this paper, we designed a kind of micro gas cell with a sub-centimeter length. The flow rate of the micro gas cell and the supersonic nozzle were compared by hydromechanics simulations. Compared to the supersonic nozzle, the flow rate of the micro gas cell was reduced by 97 percent. Moreover, the gas cell sustained a longer flattop region. The decreased flow rate is attributed to 2 reasons. 1, the area of the nozzle exit decreased significantly. In the case of the supersonic nozzle, the laser interacted with the gas jet outside the nozzle exit. Therefore, the exit size was determined by the interaction length. In the case of the micro gas cell, the laser interacted with the gas inside the gas cell. The exit only needs to be larger than the laser focal, which is much smaller than the interaction length. 2, the velocity of the gas jet was decreased. When using a supersonic nozzle, the velocity at the nozzle exit had to be high enough to generate a flattop density distribution, which is required by LWFA. As a comparison, in the micro gas cell, the gas was confined by the cell wall. As a consequence, the gas velocity had little influence on the density distribution inside the cell. By changing the inner radius of the cell, (1-4) mm long flattop regions can be generated while keeping a low flow rate. Experiments using the micro gas cell were conducted on a 45TW femtosecond laser facility at Laser Fusion Research Center. Stable electron beams with a maximum energy of 250MeV were generated. This study will contribute to the stable and high-frequency laser wakefield acceleration.


Measuring the mechanical properties of living tissue is a challenging task due to the small sizes and the fragility of the living organisms. A promising method, which works best on small scales, is the passive microrheology, which observes the motion of tracing beads within the sample. The video imaging method observes this motion by imaging the tracer particles with suitable optics (e.g. a microscope). As living tissue is a complex material, the viscoelastic properties are highly frequency dependent; therefore, a fast high-speed camera is needed to resolve the important frequencies in the 100 to 1000 Hz regime. As the data rate of high-speed cameras exceed the storage speed, only short burst of measurements can be carried out. This leads to a limited dynamic range of frequencies and missed measurement opportunities. It normally is not possible to track all the particles in real time to avoid the storage requirement of the video, as the tracking needs to be very precise and thus has a high computing demand. In this presentation, a combination of a CMOS imaging sensor with an FPGA is presented, which, in combination, allows for virtually unlimited long high-speed tracking of up to eight particles at up to 10 kHz. First, the sensor and the FPGA combinations are laid out. Secondly, the used particle tracking algorithm and its implementation is explained and benchmarked with a known state-of-the-art algorithm. Finally, this integrated sensor solution is mounted on a standard microscope and hour long tracking experiments on living 3T3 fibroblasts are carried out, studying the impact of blebbistatin on the mobility of polystyrene beads within the cell.


The Madeleine de Proust theory which is about the power of the subconscious (Bray, 2013), refers to Proust's experience of recalling his past after tasting a madeleine dipped in tea (Bray, 2013). I...


The reaction of 3-stannyl propanoates and 3-stannyl propanonitriles with sodium tert-butoxide in DMSO leads to elimination and/or substitution products. The composition of the product mixture depends on the nature of the ligands attached to tin and also on the nature of the functional group (COOMe or CN). Stereochemical results suggest that the elimination reactions proceed through an (E1cB)R mechanism.


For a torus bundle (S^1 x S^1) -> E -> S^1$, we construct a finite free resolution Z over ZG, where G is the fundamental group of the total space E, and then we compute the cohomology groups H^*(G,Z) and H^*(G,Z_p) for a prime p. We also construct a partial diagonal approximation for the resolution, which allows us to compute the cup product in H^*(G,Z) and H^*(G,Z_p).


For the water diversion project of Nanzhou Waterworks, 2-DN 2 200 pipeline will run through the Zhujiang Delta. The design for the large-scale water transmission pipeline running across the creeks is involved. The 2-DN 2 200 source water transmission pipeline near A3 mark of Xinguang Highway running across the Dashan Creek is taken for example, and the selection of construction plan and the design for pipeline running across creek are introduced in detail.


Background: It is generally accepted that the presence of angular deformity about the knee that persists into the preadolescent years will not correct spontaneously. The goal of this study was to review our experience with hemiepiphysiodesis and physeal stapling for the correction of angular deformity to establish the efficacy of these procedures and to determine their indications and the rate of correction. Methods: A retrospective review of 48 patients undergoing hemiepiphysiodesis or physeal stapling about the knee was performed. Patients were included if they had at least 2 years of documented follow-up without an osteotomy. Results: The average follow-up was 30.4 months (range, 24-52months). Genu varum was identified in 33 patients, genu valgum in 14 patients, and a windswept deformity in 1. Of the 52 limbs with genu varum, 35 were secondary to Blount disease. The group with genu varum unrelated to Blount disease presented a change in the mechanical axis from a mean of −32 degrees at surgery to a mean of − 13degrees. The patients with Blount disease presented a change in the mechanical axis from a mean of −19 degrees at surgery to a mean of −16 degrees. The group with genu valgum presented a change in the mechanical axis from a mean of 20 degrees at surgery to a mean of 2 degrees. Conclusions: Hemiepiphysiodesis is an effective means for correcting angular deformity about the knee in skeletally immature patients with both genu valgum and genu varum, so long as the genu varum is unrelated to Blount disease. Hemiepiphysiodesis is effective in preventing the progression of deformity in patients with Blount disease. Level of Evidence: Therapeutic-Level IV.


The sensitivity of vegetative cells and ascospores of Saccharomyces cerevisiae to a range of biocides used in food industry hygiene was compared. Ascospores were significantly more resistant to quaternary ammonium compounds and hypochlorite but not peracetic acid. Ascospores also showed greater tolerance of desiccation than vegetative cells.