Thin-walled cylinders, used in a variety of engineering applications, are often subjected to situations where the applied loading is not limited to a single loading type. The introduction of multiple loads alters the stability characteristics of the system in a manner that must be understood to maintain structural integrity and abide by safety regulations. The present study investigates the elastic buckling response of thin-walled cylindrical shells under a combination of torsional loads and circumferentially-varying thermal loads.


Objective: Identify the causes for discontinuation of temporary contraceptive methods in students from a University of Lima, Peru. Material and methods: Descriptive and cross-sectional study, realized in obstetric students from Universidad Nacional Mayor de San Marcos that discontinued the use of the last contraceptive method. The sample was made up of 51 university students. Relative and absolute frequencies were estimated; also, the differences between analysis groups were made using the Chi Square Test (x2) or Fisher's Test. Results: The age range is between 19 to 24 years old (76,5%) and the single marital status prevailed (98%). The most frequent contraceptive method was preservative (41,2%), followed by the quarterly injectable (25,5%). The most relevant causes to discontinuity the contraceptive method used were the low availability of time to go a Health Center (72,5%) and the difficult to go when collateral effects appears (62,7%); among the least frequent was the one related to the parents' influence and/or relatives (7,8%). Conclusion: The difficult in the access and low availability of time to search a Health Center with specialized attention were the principal causes to discontinuity of contraceptive.


Keyword technique has been investigated extensively in the literature to examine its effectiveness on L2 pronunciation. However, previous studies have not examined how computer-assisted keyword technique could aid L2 learner to pronounce weak forms in English accurately. Therefore, this study aims at investigating the effect of computer-assisted keyword technique on acquiring weak forms pronunciation. A total of 60 Arab EFL learners participated in the study and assigned into three groups. The first group viewed a video containing weak forms in English dubbed with L1 keyword. The second group was taught weak forms and aided with keyword traditionally. The third group was taught the same content using traditional way without keyword. Results of the post-tests indicated that participants in keyword technique (either computer-assisted or traditionally) outscored the participants who did not use keyword technique. The study concluded that keyword technique, either used with the help of computer or used traditionally, is a useful tool to enhance weak forms pronunciation.


A field experiment was conducted to study the response of microbes and bioregulators on yield growth and productivity of chickpea ( Cicer arietinum L.) under rainfed condition during 2010-11 and 2011-2012 on sandy loam soils with factorial randomized block design consisting of four levels of biofertilizers inoculation viz., no inoculation, phosphate solubilizing bacteria (PSB), vesicular arbuscular mycorrhizae (VAM) a nd PSB+VAM with two bio-regulators viz., homo-brassinolide @ 1 ppm and gibberelic acid @ 1000 ppm at pre-flowering and pod-filling stage. Result showed that the y ield attributes like number of grains plant -1 and test weight were highest in treatment receivi ng homo -brassinolide and dual inoculation of PSB+VAM. Grain yield was highest (2139 and 2211 kg ha -1 ) in treatment receiving PSB+VAM application over no inoculation (957 and 1072 kg ha -1 ). The grain yield was highest (1705 and 1797 kg ha -1 ) in treatment receiving homo-brassnolide and lowest grain yield (1481 and 1569 kg ha -1 ) at gibberelic acid during 2010 -11 and 2011 -12, respectively.


Objective:To study the effects of Mycobacterium vaccae vaccine on eosinophil apoptosis,protein expression of Fas and bcl-2 in lung tissues of asthmatic guinea pig.Methods:30 guinea pigs were randomly divided into NS,asthma and Mycobacterium vaccae vaccine group.A guinea pig model of asthma was estbalished with OVA(ovalbumin).Each guinea pig of Mycobacterium vaccae vaccine group was injected intramuscularly with 22.5μg of Mycobacterium vaccae vaccine 10 days before OVA immunization.After the last challenge,TdT-mediated dUTP nick end labeling (TUNEL)technique was used to determine the apoptosis of eosinophils and immunohistochemistry method was used to determine protein expression of Fas and bcl-2 in lung tissue sections.Results:Guinea pigs of Mycobacterium vaccae vaccine group had a higher AI(apoptosis index) of eosinophils in lung tissues[(23.8±5.4)%]than that of asthma group[(4.6±0.7)%,P0.01],a higher expression of Fas protein(optical density value,OD value)in lung tissues[(0.202±0.013)]than that of asthma group[(0.051±0.025),P0.01],and a lower expression of bcl-2 protein(OD value)in lung tissues[0.054±0.032)]than that of asthma group[0.181±0.041),P0.01].Conclusion:Mycobacterium vaccae vaccine can induce the apoptosis of eosinophils in lung tissues of asthmatic guinea pigs by up-regulating the expression of Fas protein and down-regulating the expression of bcl-2 protein in lung tissues.


This publication is based on the English course that strengthened the language skills of the teachers in the School of Industry and Natural Resources at Lapland University of Applied Sciences. The course was funded by the Northern Mining Network project, in which Lapland and Kajaani Universities of Applied Sciences are together developing international cooperation and networking in the mining industry.

The participants of the suggestopedic intensive English course were teachers, senior lecturers, principal lecturers and project workers from R&D at Lapland UAS. The target was to be prepared to give lectures in English and to be able to participate in international projects.

This publication gathers together presentations written during the course. The articles include presentations of the current state of the mining industry, teaching, laboratories at Lapland UAS, projects, etc. The course was a success, and the results, namely being able to speak and learning mining-specific vocabulary, developed decisively.


Pu-erh is a variety of fermented and aged dark tea produced in Yunnan province, China. Fermentation is
a tea production style in which the tea leaves...


This book studies comics (bandes dessinées or BDs) that present the biographies of three French existentialist philosophers: Jean-Paul Sartre, Simone de Beauvoir, and Albert Camus. The three BDs are Sartre: une existence, des libertés (by Mathilde Ramadier, Anaïs Depommier, and Nawëlle Saïdi (Paris: Dargaud, 2015)), Simone de Beauvoir: une jeune fille qui dérange (by Sophie Carquain and Olivier Grojnowski (Paris: Marabulles, 2021)), and Camus: entre justice et mère (by José Lenzini and Laurent Gnoni (Toulon: Soleil, 2013)). Elizabeth Benjamin explores the connection between biographical BDs and existentialist philosophy while reasserting the value of the comics medium beyond its application by engaging in abstract concepts. The book contributes to the theory of comics by offering a sketch for a theory of biography in comics through a close analysis of the BDs along with a discussion of their philosophical aspects. Drawing on the ethical works of these three philosophers Sartre's L'Existentialisme est un huma nisme (1946), Beauvoir's Pour une morale de l'ambiguïté (1947), and Camus's L'Homme révolté (1951) as well as the genre of biography in all of its forms, Benjamin outlines the theoretical foundation of her analysis. She makes specific reference to David Carrier's The Aesthetics of Comics (University Park, PA: Penn State University Press, 2000) among other theory books on comics. While Benjamin's research method is grounded in comics studies, philosophy, and the author's analysis beyond disciplinary bounds, the critical thrust of this monograph stems from her reading of the three BDs. Chapters devoted to each thinker study their main philosophical thoughts and demonstrate how the comics medium embeds abstract notions within itself. For instance, borderless panels can illustrate the timeless space, and the notion of unreachable truth can be shown in drawing and redrawing settings. Chapter 2 focuses on Sartre; after introducing the classic representative of French existentialism, Benjamin presents an analysis of Sartre: une existence, des libertés. The chapter compares the concepts of narrative and anti-narrative with Sartrean views on the formation of meaning and personal narrative (for instance the idea of Being in both BD and philosophy). The following chapter pivots towards notions such as freedom, the authorial voice, and ambiguity in Beauvoir's œuvre. Chapter 4 is organized around three themes based on how the methods of Camus: entre justice et mère overlap with Camus's philosophical ideas: the use of colour in BD and its connection to the artist's ideas about sound and silence; superimposition and reality; and Camus's theories of the absurd and its connection to BD's capacity to blur boundaries. In Chapter 5, the author transitions from analysing the three BDs to looking at a more thorough analysis of the existentialists' comics legacy by evaluating existentialism as a philosophy and the 'for beginners' literature devoted to these three thinkers, and their appearance in other comics such as Dick Matena's Sartre & Hemingway (1993), Nick Gibb's Dead Philosophers in Heaven (2010–16), and Noël Tuot and Daniel Casanave's Baudelaire (2006). This is an engaging text for all readers interested in comics studies.


This article traces the rise of modern oil culture to interlocking innovations in British fiction, political economy, natural science, and colonial capitalism. It advances a method called "transitive reading" to understand those innovations and to show how writers first conceived of oil in relation to established energy inputs such as coal. The article then reads Joseph Conrad's late masterpiece, Victory (1915), as an ambivalent artifact of the British petro-imagination. In representing the "liquidation" of overseas coal capitalism, Victory articulates a desire for freedom from carbon power, while nevertheless binding that desire to a world where petroleum or "liquid coal" was becoming increasingly constitutive of the self.


— Climate change is real! In the recent years the global average temperatures have been increasing steadily due to global warming. One of the main reasons for global warming are the expulsion of gases from vehicles, another aspect is that we are running out of fossil fuels. One way which is mutually going to help in both aspects replacing petroleum run vehicles by power train Electric vehicles. Power train electric vehicle is formed by three components - Engine , Transmission, and Drive train, these are the components which gets engines power to the wheels, and then down to ground. The components of power train converts the stored energy into kinetic energy by utilising various power sources and non wheel based vehicles for propulsion purpose. This paper proposes Electric power train designed for Electric bike. These are light weight and efficient vehicles which require less maintenance and also eco-friendly.


For some time, point-differential has been thought to be a better predictor for future NBA success than pure win-loss record. Most ranking and team performance predictions rely largely on point-differential, often with some normalizations built-in. In this work, various capping and weighting functions are proposed to further improve indicator performance. A gradient descent algorithm is also employed to discover the optimized weighting/capping function applied to individual game scores throughout the season.


We perform a convergence analysis for discretizations of Helmholtz scattering and resonance problems obtained by Hardy space infinite elements. Superalgebraic convergence rates with respect to the number of Hardy space degrees of freedom are achieved. We consider spheres and piecewise polytopes as transparent boundaries. The analysis is based on a G\aa rding-type inequality and standard operator theoretical results. While the obtained results are related to those for the radial perfectly matched layer method, different techniques are used in the analysis.


Nowadays, most of latex pillow products in case study are produced and stored all in 5 warehouses located in southern region of Thailand which causes inconvenience to satisfy the customers' orders from other regions that is far away from current sites. Therefore, the main purpose of this study is to determine the optimal locations and number of distribution centers (DCs) that is one of the important ways to increase the potential to response to the customers' needs. By applying the geographic information system (GIS) with maximize coverage model in location-allocation problems, the solution was covering as many customers as possible within the services distance of distribution centers, including establishing cost of the distribution centers. The finding of this study found that two optimal distribution centers, Dong Khoi in Phetchabun Province and Nong Sai in Suratthani Province, where cover as 99.99% of demands within the service distance 500 kilometers and there were establishing cost of both is 2.55 million Baht.


Objective To investigate the scores of social support and coping style of patient with diabetic foot and explore the correlation-ship between social support and coping style of the patients.Methods 120 patients with diabetic foot were investigated on their social support and coping style by social support measuring scale and medical coping questionnaire.The correlation-ship between social support and coping style was analyzed.Results The coping styles of the two groups were significantly different.Compared with the patients with slighter diabetic foot(grade 0),those with severer diabetic foot(≥grade 1) had lower confronting score [(17.82 ± 1.98) vs.(9.48 ± 2.81),P=0.00], higher evading score[(16.17 ± 2.74) vs.(14.44 ± 2.97),P=0.00] and higher yielding score [(10.87±1.90) vs.(8.81±3.17),P=0.00].The social supports of the two groups were also significantly different.The patients with severer diabetic foot(≥grade 1) had less subjective support [(37.24 ± 5.74) vs.(42.68±6.28),P=0.00],less objective support [(34.56 ± 2.63) vs.(54.13 ± 3.2)]and lower social availability [(39.56 ± 6.51) vs.(43.28 ± 5.32),P=0.00]than those with slighter diabetic foot(grade 0).In patients with diabetic foot,there were positive correlation between social support and confronting ability(r=0.624,P=0.003);there were negative correlation between social support and evading ability(r=0.578,P0.00),and between social support and yielding ability(r=-0.722,P0.00).Conclusions The patients with severer diabetic foot have poorer positive coping ability and less social support.In patients with diabetic foot,social support is significantly associated with coping style.Nurses should pay attention to increase their social support and improve the positive coping ability in order to improve their prognosis and quality of life.


In mammalian cells, DNA is often subjected to stresses such as ionizing radiation (IR) and ultraviolet light that can induce DNA double strand breaks (DSBs). In response to DNA DSBs, mammalian cells activate a rapid phosphorylation signaling cascade through the protein kinases, Ataxia-Telangiectasia Mutated (ATM) and ATM- and Rad3-Related (ATR).1 Many well-characterized DNA repair factors are phosphorylated by ATM in response to DSBs, and the sequential phosphorylation of some of these factors, including NBS1, delay cell cycle progression (checkpoint arrest) to allow time for DNA damage repair.2 Results from a new study suggest that phosphorylation of NBS1 is regulated by the acetylation status of the protein, which is modulated by SIRT1 deacetylase.


EDITOR,—Paul Aylin and F Azeem Majeed point out that they did not have data on admission rates or bed occupancy during the …


the student of marketing, several references from the marketing literature relevant to the topics covered are missing. This is often the case with a book written by psychologists primarily for students of psychology. From a literature search standpoint, however, the book is an excellent departure point from which a reader can move into the social sciences citation index and identify articles in marketing that cite relevant psychology literature.


Organic afterglow with ultralong room-temperature phosphorescence (OURTP) has inspired extensive attentions recently, but remains a intrinsic challenge in boosting OURTP performance with simultaneously elongated lifetime (τp) and improved quantum yields...


Alveolar macrophages (AMs) are a critical element of the innate immune response to inhaled agents, yet functional and genetic studies of this unique macrophage population are lacking. Current strategies to obtain large quantities of AMs are cumbersome and inefficient. This is due largely to both the high cost of time and resources involved in the extraction of AMs and the inability to effectively culture AMs ex vivo for extended periods of time. While bone marrow derived macrophages (BMDMs) are modeled in numerous immortalized cell lines, AMs currently lack an acceptable model that can be used in vitro. Recently, self-replicating cells derived from the fetal mouse liver, termed "MPI" cells, have been shown to possess AM-like characteristics. Here, we show that early after isolation, these cells are SiglecFhi, Cd11chi, and Cd14low, while also expressing high levels of Pparg, Marco, Itgax, and Car4, akin to AMs. Additionally, like AMs, MPI cells effectively efferocytose dead cell debris and phagocytose silica particles. While these cells lose their "AM-likeness" over time, addition of the cytokine TGF-β dramatically delays this shift away from the AM-like phenotype. Gene expression analysis shows that in contrast to cells treated with TGF-β, untreated MPI cells cease expressing Tgfbr1, the receptor for TGF-β, concurrent with the shift away from the AM-phenotype. Further, these cells are amenable to viral transduction, and we have successfully employed CRISPR/Cas9 targeted genetic editing in MPI cells. These findings further our understanding of MPI cells as an accessible and genetically tractable model for AMs that allow for long-term and large-scale studies that are not possible with AMs isolated ex vivo.


A precision reducer with a high ratio and a small size is essential for precise control of the position of a robotic arm. The rotate vector (RV) is a reducer widely applied in robotic joints. However, its complex structure, over-positioning and difficult assembly restrict its application industrial robots. Herein, a novel abnormal cycloidal gear (ACG) reducer is proposed. In comparison to the RV reducer, the proposed reducer has the characteristics of compact structure, less over-positioning and high ratio. The compound tooth profile of "epicycloid-involute hypocycloid" is used as the driving teeth for improving the performance of the reducer. The operating principle, mechanism design and reduction ratio of the proposed reducer is investigated, and the design method of the ACG tooth profile is also introduced. A dynamic characteristic model is established to verify the correctness of the design method of the reducer. A prototype of the ACG reducer is fabricated by using the computer numerical control (CNC) machining technology. Results show that the ACG reducer is capable to cover a wide range of reduction ratios with a simple mechanism. The numerical and theoretical results are in agreement, which depict the structural feasibility and correctness of the design method of the reducer. The adaptation of the ACG tooth profile as the driving teeth helps in improving the performance of the reducer.


The performance of a new-design flat plate solar water collector was studied in the current work. The influences of the inner rings and their axial distance, in the absorber surface heat pipe, on the performance of a new-design flat plate solar water collector were studied. Fluid flow and heat transfer in the collector panel were numerically simulated using the computational fluid dynamics (CFD) technique. The results of the flow distribution along the absorber surface of the heating pipe showed that; for the case of heat pipe without inner rings, the water outlet temperature from the heat pipe reached to 326.8 K. While; in the case of using the inner rings, at an axial distance of 5 cm, the water outlet temperature was increased to 338.8 K, for the same simulation conditions. Also, the maximum calculated efficiency of the solar collector for the case without using the inner rings was 60 %, while this value recorded 82.2 % for that case of using the inner rings. The current research work was compared against a previous experimental work running at the same conditions. The comparisons showed a considerable agreement between the simulated and the experimental results.


Surface property of coal is one of important factors determining coal flotability.The Quanta 250(FEI) environmental scanning electron microscope and Bruker QUANTAX400-10 electric refrigeration spectrometer were used to analyze SEM surface distribution of coal with different oxidation time.The results show that with the increasing of oxidation time,the number of hole on the surface of coal increases and the crack appears along the holes,the ash elements(Si,Al) contents on the surface of the coal increase.The average gray scale values analysis shows that the decreasing trend of carbon content and oxygen content becomes slow.The Zeta potential of coal is negative and decreases gradually with the oxidation time increasing.The decreasing trend of the Zeta potential also becomes slow.As oxidation time increases,the average gray values and Zeta potential on the surface of coal particles have the similar variation.


The effects of Ge occupations at Sb and Mn sites in Mn2Sb system had been re-examined along with the influence of hydrostatic pressure. The metamagnetic phase transition from ferrimagnetic (FRI) to antiferromagnetic (AFM) state was observed in Mn2Sb1-xGex (x = 0.05, 0.1) and (Mn1-yGey)2Sb (y = 0.025, 0.04) alloys. The phase transition temperature, Tt, was gradually increased with increased Ge substitution for both Sb and Mn, but slightly decreased under increased hydrostatic pressure in Mn2Sb0.95Ge0.05 alloy. Meanwhile, the slope of critical field as the function of temperature was reduced with increased hydrostatic pressure and Ge substitution amount in (Mn1-yGey)2Sb (y = 0.025, 0.04) alloys. For a field change of 7 T, the maxima of magnetic entropy changes of 6 Jkg-1K-1 and 7.1 Jkg-1K-1 have been achieved in Mn2Sb0.95Ge0.05 and Mn1.95Ge0.05Sb alloys, which are gradually decreased by more Ge substitution and increased hydrostatic pressure.The effects of Ge occupations at Sb and Mn sites in Mn2Sb system had been re-examined along with the influence of hydrostatic pressure. The metamagnetic phase transition from ferrimagnetic (FRI) to antiferromagnetic (AFM) state was observed in Mn2Sb1-xGex (x = 0.05, 0.1) and (Mn1-yGey)2Sb (y = 0.025, 0.04) alloys. The phase transition temperature, Tt, was gradually increased with increased Ge substitution for both Sb and Mn, but slightly decreased under increased hydrostatic pressure in Mn2Sb0.95Ge0.05 alloy. Meanwhile, the slope of critical field as the function of temperature was reduced with increased hydrostatic pressure and Ge substitution amount in (Mn1-yGey)2Sb (y = 0.025, 0.04) alloys. For a field change of 7 T, the maxima of magnetic entropy changes of 6 Jkg-1K-1 and 7.1 Jkg-1K-1 have been achieved in Mn2Sb0.95Ge0.05 and Mn1.95Ge0.05Sb alloys, which are gradually decreased by more Ge substitution and increased hydrostatic pressure.


Conversational information retrieval is a relatively new and fast-developing research area, but conversation itself has been well studied for decades. Researchers have analysed linguistic phenomena such as structure and semantics but also paralinguistic features such as tone, body language, and even the physiological states of interlocutors. We tend to treat computers as social agents—especially if they have some humanlike features in their design—and so work from human-to-human conversation is highly relevant to how we think about the design of human-to-computer applications. In this article, we summarise some salient past work, focusing on social norms; structures; and affect, prosody, and style. We examine social communication theories briefly as a review to see what we have learned about how humans interact with each other and how that might pertain to agents and robots. We also discuss some implications for research and design of conversational IR systems.


The research reported upon in this paper describes an effective method of gust alleviation using direct measurements of atmospheric turbulence to drive the aircraft control surfaces in a way that attempts to directly counter or cancel those forces and moments produced on the aircraft by gusts. The method yields a feedforward or open loop control law, simple to mechanize and relatively insensitive to changes in flight condition. When applied directly, the resulting control law effectively gust-alleviates in the low frequency phugoid and short period range but has a tendency to amplify structural mode vehicle motions due to the phase lag of the actuators. A method of design based upon the use of a diagonal or Jordan form of the equations of motion enables the designer to avoid this problem of structural mode excitation.


Micropropagation methods are often used to supplement existing clonal programmes for Eucalyptus species. However, genotypic differences among clones require the implementation of clone-specific protocols, an expensive and labour-intensive exercise. Hence, this study aimed at determining high-yielding hybrid-specific rather than clonespecific, micropropagation protocols for E. grand is x nitens (GN), E. grandis x nitens (NB), and E. grandis x urophylla (GU). Different conditions for surface sterilisation, bud-break (3 protocols, 2 media), multiplication (4 media), elongation (2 protocols) and rooting (4 media) were tested. A single successful surface sterilisation approach was possible for all clones of the tested hybrids (0.0-11.8% contamination, 0.0-22.9% necrosis). It involved rinsing nodal explants in a fungicide mixture (lg/l Benlate, 19/1 boric acid, 0.5ml/1 Bravo, Tween 20) for 15 minutes followed by calcium hypochlorite (lOg/I with Tween 20) for three minutes. Results at each culture stage were dependent on genotypes, and results indicated here represent ranges in values among the clones of each hybrid. The highest bud-break values for GN clones (87-90%) and NH clones (17-75%) were achieved on a medium containing MS, O.lmg/1 biotin, O. lmg/l calcium pantothenate, 0.04mg/1 NAA, O.llmg/l BAP and 0.05mg/1 kinetin. In GU clones, budbreak values on this medium (84-97%) were not significantly different to those achieved directly on a multiplication medium (80-91%) (MS, 0.1 mg/l biotin, 0.1 mg/I calcium pantothenate, 0.2mg/l BAP, O.Olmg/1 NAA). Shoot multiplication yields for GN clones (4-13 shootslbud) and GU clones (2-6 shootslbud) were achieved on a medium consisting of MS, O.lmg/1 biotin, 0.1 mg/I calcium pantothenate, 0.2mg/1 BAP and 0.01 mg/I NAA. As genotypic effects were highly significant among NH clones, a single multiplication medium for all clones of this hybrid could not be determined. The best method of elongation for clones of all three hybrids involved culturing shoots on MS, 0.1 mg/I calcium pantothenate, O.lmg/1 biotin, 0.35mg/1 NAA, O.lmg/I kinetin and O. lmg/1 IBA, under photoperiod conditions, rather than total darkness, for 6 weeks. This resulted in 82.3-86.6% elongation and shoot lengths increasing by 22.9-35.2 mm for GN clones, 80.2-82.3 % elongation and an increase in length of 24.7-32.2 mm for NH clones and 70.8-78.1 % elongation, and shoot elongation of 21.6-29.3 mm for GU clones from


Harmonious finance ecological environment is an essential fundamental of the region's economic development. This paper points out the problems of building harmonious finance ecological environment of Jingzhou Region through analyzing the current status of its finance ecological environment, and based on this some reflections has been made.


The treatment of aggressive B‐cell lymphomas is in evolution, largely based on the recognition of major genetic and biologic subtypes harboring distinct pathogenetic lesions. In this review, we will consider current treatment options with the caveat that many trials do not address some of the high‐risk subsets with enough power to conclude on definitive approaches. Since its introduction in 1976, CHOP has been the backbone of treatment in aggressive lymphomas. Efforts to improve upon CHOP have included shortening the cycle length (14 days versus 21 days), adding more cytotoxic agents, or delivering chemotherapy in an infusional regimen (ie, DA‐EPOCH‐R). However, a pivotal US intergroup study showed that "more" chemotherapy does not improve survival and only added toxicity, and serial European trials have shown that any benefit from added etoposide or shortening of the treatment cycle disappeared once rituximab was introduced. The major advance in diffuse large B‐cell lymphoma (DLBCL) came with the addition of rituximab to CHOP, which improved survival by approximately 15% to 20% across age groups, and established R‐CHOP as the standard of care. Despite the overall success of R‐CHOP, it is clear that many patient subsets are not cured (Figure 1). From a clinical perspective, elderly patients and patients with a high International Prognostic Index (IPI) have cure rates of approximately 50% (Table 1). From a biologic perspective, DLBCL has emerged as an extremely diverse disease. The 2016 WHO update highlights the heterogeneity of aggressive B‐cell lymphomas via the following changes: the requirement for cell‐of‐origin (COO) testing, the elimination of B‐cell lymphoma, unclassifiable (BCLU), and replacement by high‐grade lymphomas with shared genetic lesions (ie, dual MYC and BCL2 or BCL6 rearrangements, "double hit lymphoma [DHL]") as a separate entity and the acknowledgement of dual expression of MYC and BCL2 (double expressor lymphomas [DEL]) as an adverse prognostic feature. With these updates in mind, should the treatment of aggressive B‐cell lymphomas be altered? Unfortunately, as the discussion below


During the past twelve months RJ Lee Group has manually collected and published over one hundred thousand composite SEM images consisting of three components: a low magnification image, a high magnification image, and an x-ray spectrum. In addition, about one and one-half million discrete features have been automatically located and compositionally/morphologically characterized, with about one-fourth of those features then having ancillary images collected automatically based upon characterization criteria. Finally between ten and twenty thousand images have been collected for the production of image montages. The output of this effort has been systematically entered into networked databases where it is accessed for post-processing, analysis, and report generation.


Letter/diary written to his brother-in-law, Rev John N Garland, dated 26 Jan 1842 which covers events 20 Sep 1841-7 Mar 1842
Thomas John Thompson was a cabin passenger. He married fellow passenger Sarah Hargreaves (1827-1913) at Nelson in 1846
Quantity: 1 Electronic document(s).
Processing information: Part of SBDD (shipboard diary digitisation) project


The paper analyzes the characteristics of the graduation design of integrated training cadets and provides suitable methods of choosing topics and guiding the design in the light of the design requirements.The methods are useful for it is derived from practice.


In the valuation of forest resources, the alternative use of the land is one of the central themes. In most cases it is made without taking into account the uncertainty and the possible flexibility of the alternative use. Within these alternatives, the strategy of shifting to a more profitable and sustainable crop is a well-studied topic in forest research. Although the transformation opportunity could add great value to the project, the valuation of this flexibility is obviated by traditional discounted cashflow criteria (NPV). The application of real options theory (ROT) makes it possible to assess this flexibility based on the uncertainty that the transformation entails. However, the hypotheses that are made about the future evolution of the underlying asset, in this case the value of the new crop, may condition the precision of the result. Usually some researchers model these conversions under the hypothesis of geometric Brownian motion (GBM), hypotheses that are not plausible when the new crop has a strong seasonal component. In this work, an adapted model framework is proposed to evaluate forest transformation opportunity into another crop when land use has both high agronomic potential and high seasonal component, a context in which classic real options framework is not applicable. As a work based on a theoretical model, after methodological motivation, the strawberry crop is chosen as alternative due to its seasonal component. Using private data for this crop, we model through the Ornstein–Uhlenbeck process, with mean-reversion (MR) to a seasonal component, and then we use of Longstaff and Schwartz's algorithm to calculate the option value. The results show that when considering flexibility in option valuation it leads to an increase on the return of more than 4%. Furthermore, robustness analysis evidence shows that option value is very sensitive to seasonal component, reinforcing previous evidence that suggests that the MR process offers a more accurate and appropriate valuation over the traditional GBM in the arena of agronomic potential valuation. Specifically, the result of valuing this transformation through the MR process is between 1.5 and 1.7 times the value of the NPV, which results in approximately a 13% annual return. If GBM had been used, the valuation would have been a 72% annual return, an unrealistic result in this context, due to the non-consideration of the seasonal mean-reverting prices process.


Engages a projection 34 formed on the outer circumferential edge portion of the tank 2 in the groove 36 of the formed brazing material supply member 23, further, by engaging at least the engagement groove 39 formed in the connector 9, prior to brazing But placing tank 2, the brazing material supply member 23 and the connector 9 in a stable fitting state. Thus, a tank brazing material layer is not formed on the surface, a solution supply means of the brazing material to the brazing of the connector which is formed by cutting and, together supply means of the brazing material and detachment of made member can be prevented.


Objective To investigate the differentiation of transplanted P19 cells and improving of heart function using MI model of rat.Methods Sprague-Dawley rats(n=30) were separated randomly into two groups: treatment group(n=20) and control group(n=10).Left ventricle of the animal's heart was cryoinjured to create a transmural infarct.Then,P19 cells were transplanted into the transmural lesion and border lesion immediately.At eighth week after transplantation,the living cells and differentiation of transplanted cells were observed morphologicly and heart function of two groups were measured.Results Living transplanted cells were found in the lesion of MI,and the cells shown positive of GATA-4、α-sarcomeric actin and myogenin in immunohistochemical staining.Compared with control group,LVEDP was lower in treatment group(P0.01),LVSP and ±dp/dt_(max) were higher in treatment group(P0.01).Conclusions After P19 cell transplantation,transplanted cell can living in transmural lesion and have a tendency to differentiate to muscle cell in MI model.P19 cell transplantation may be a novel approach to improve ventricular function in transmural infarct.P19 cell is a feasible modal cell to study the cellular therapy for heart failure.


This article introduces the notion of chaotification (or, anticontrol of chaos), which means to make an originally non-chaotic dynamical system chaotic, or to enhance the existing chaos of a chaotic system, via feedback control techniques. The discrete case is discussed in somewhat detail, while the continuous case is outlined briefly. Basic theories and methods are described, and potential applications are mentioned as motivation of the research.


Stress-induced cardiomyopathy is a relatively rare, unique entity that has only recently been widely appreciated. It characterized by transient left ventricular regional wall motion abnormalities (with a peculiar apical ballooning appearance), chest pain or dyspnea, ST-segment elevation and/or T wave inversion and minor elevations of the cardiac enzyme levels. The patients in the previous series were usually women over 50 years of age and a triggering event was identified in most cases; these included severe emotional distress or an acute medical illness. Although reports of single episodes of stress-induced cardiomyopathy are not infrequent in the recent medical literature, we report here on a case of stress-induced cardiomyopathy in a young women, and this was related with the postpartum period as a stressful condition. (Korean Circulation J 2007;37:388-392)


Introduction: The discrete nature of blood flow in capillaries permits the measurement of PO2 gradients between erythrocytes (RBCs), manifest as rapid fluctuations in PO2 known as EATs. Mathematical models have predicted that RBC spacing in capillaries is a critical determinant of EAT magnitude.


Structural and functional correlation of lung status during pre-clinical research can markedly improve the quality of experimental claims made by individual research teams. Therefore, we sought to image the lung airways and vasculature by employing high-resolution $(8 \mu \mathrm{m)$ dual K-edge subtraction synchrotron x-ray computed tomography at the Canadian Light Source. Previously, we have shown that angiostatin, an endogenously cleaved anti-angiogenic molecule, protects against exuberant neutrophil migration, activation and vascular leak in murine endotoxin challenge model without diminishing the host immune response. We utilized barium and iodine based K-edge imaging by injecting a mix comprised of in-house prepared barium microparticles and standard iodine contrast solution via jugular vein. Lungs from respective treatments were excised and embedded in agarose under vacuum. Imaging was accomplished at four different energy levels, to cover the barium and iodine upper as well as lower K-edge. We observed well preserved architecture with very thin airway and vascular compartments in saline treated lungs. Conversely, endotoxin treatment produced markedly leaky vascular walls along with compromised alveolar septa. Angiostatin and endotoxin treatment offered complete protection against vascular leak as shown by well-preserved vasculature as well as alveolar septa. This study presents evidence of the protective effect of angiostatin in endotoxin induced acute lung injury.


A mixture of two chemically pure glycosides obtained from the stem bark of Symplocos spicata Roxb was studied for pharmacological actions. The glycosides (5 mg/kg, ip) possessed marked relaxant effect (equipotent with the relaxant effect of 10 'g/kg, iv adrenaline) on intestine in situ and transient hypotension in anaesthetised dog and moderate relaxant effect on isolated rabbit ileum. The spasmogenic responses of DMPP and acetyl-choline were attenuated by 40% and 55% respectively on isolated guinea-pig ileum. The glycosides had positive inotropic and chronotropic actions on perfused frog's heart and a weak curare-like activity on isolated frog's rectus abdominis muscle. The glycosides did not have any CNS activity.


1 Centro de Iniciativas Democraticas de Panama, Panama. Correo electronico: email@example.com Av. Justo Arosemena, Calles 40 y 41, Panama, Republica de Panama. Using the theoretical and methodological frameworks of Political Economy of Media and Culture, the ruptures and continuities in the structures of the press, radio and television in Panama are identified. This article also analyses the concentration degree of these industries using three different schemes, leaving room to make comparisons of each media and to contrast the Panamanian media context with the one in other countries.


After the long predominance of a literary tradition,' modern Western cultures have returned to orality with a 'leap from the being writtenoriented to the being oral-oriented.'2 In the case of Italian, such shift 'dalla scritturalita verso l'oralita,'3 culminating in the Eighties, has led linguists to theorise, on the language continuum, the central varieties of 'italiano dell'uso medio,'4 and 'italiano neo-standard.'5 Moving


Motivation Core sequencing facilities produce huge amounts of sequencing data that need to be analysed with automated workflows to ensure reproducibility and traceability. Eoulsan is a versatile open-source workflow engine meeting the needs of core facilities, by automating the analysis of a large number of samples. Its core design separates the description of the workflow from the actual commands to be run. This originality simplifies its usage as the user does not need to handle code, while ensuring reproducibility. Eoulsan was initially developed for bulk RNA-seq data, but the transcriptomics applications have recently widened with the advent of long-read sequencing and single-cell technologies, calling for the development of new workflows. Result We present Eoulsan 2, a major update that (i) enhances the workflow manager itself, (ii) facilitates the development of new modules, and (iii) expands its applications to long reads RNA-seq (Oxford Nanopore Technologies) and scRNA-seq (Smart-seq2 and 10x Genomics). The workflow manager has been rewritten, with support for execution on a larger choice of computational infrastructure (workstations, Hadoop clusters, and various job schedulers for cluster usage). Eoulsan now facilitates the development of new modules, by reusing wrappers developed for the Galaxy platform, with support for container images (Docker or Singularity) packaging tools to execute. Finally, Eoulsan natively integrates novel modules for bulk RNA-seq, as well as others specifically designed for processing long read RNA-seq and scRNA-seq. Eoulsan 2 is distributed with ready-to-use workflows and companion tutorials. Availability and implementation Eoulsan is implemented in Java, supported on Linux systems and distributed under the LGPL and CeCILL-C licenses at: http://outils.genomique.biologie.ens.fr/eoulsan/. The source code and sample workflows are available on GitHub: https://github.com/GenomicParisCentre/eoulsan. A GitHub repository for modules using the Galaxy tool XML syntax is further provided at: https://github.com/GenomicParisCentre/eoulsan-tools Contact firstname.lastname@example.com


This article focuses on militiamen"s training perfection as a factor of improvement of militia"s activity quality. It is noted that development of communicative abilities and culture is necessary in the modern world as well as specifically in militiamen"s training as a success of their activity depends on a choice of a proper method of communication. Development of communicative culture of militiamen has theoretical and practical importance.


The aim of this study is to measure and quantify perceived intensity of discomfort due to vibration in a vehicle in situ considering complete vehicle dynamic behaviour. The shaker table based discomfort curves or the road test results may not accurately and universally indicate the true level of human discomfort in a vehicle. A new experimental method, using a seated human in a car on the four-post rig simulator, is proposed to quantify discomfort. The intensity of perception to vibration decreased with decreasing input and increasing frequency; the rate of change is different from the published literature; the difference is large for angular modes of inputs. Vehicle dynamic response is used to inform and analyse the results. The repeatability of the method and the fact that they are in situ measurements may eventually help reduce reliance on the road tests. Furthermore, discomfort curves obtained, subsequently, can be used in predictive models.


Despite global mitigation efforts, climate change will impact the City of Vancouver's future. One anticipated impact, sea level rise, is described. A comprehensive understanding of the consequences of these impacts is necessary to guide the process of identifying preferred adaptation strategies. A methodology for a coastal flood risk assessment (CFRA) of sea level rise is provided. The inputs for this risk assessment include inundation mapping and an asset-at-risk inventory. These data sets are combined with flood damage information from Hazus to look at consequences of coastal flooding. There are many uncertainties and gaps in the process of developing a CFRA for a modern, dense, urban city such as Vancouver, particularly when the planning timelines required for preparing and adapting to sea level rise are long. The value of the process and results include increased understanding of hazards and vulnerabilities, and the development of useful visual tools for engagement, planning and education.


Objective To compare the effect about three kinds of methods terminating middle gestation. Methods 180 cases of middle gestation were divided into three groups. Out of 180 cases,amnion injection with ethacridine,mifepvistol with misoprostol and amnion injection with ethacridine company with using mifepvistol were performed on 58 cases,62 cases and 60 cases respectively. To compare the effect of three groups that terminated middle gestation. Results The effect of using mifepvistol with misoprostol and amnion injection with ethacridine company with using mifepvistol were higher than that of amnion injection with ethacridine,and the time terminating middle gestation were shortened. But there were more side effects of using mifepvistol with misoprostol than those of amnion injection with ethacridine company with using mifepvistol. Conclusion The method of amnion injection with ethacridine company with using mifepvistol that terminated middle gestation has advantages of good effects,short terminating time and few side effects.


Korea Research Institute of Chemical Technology, Daejon, KoreaReceived December 1, 1998250 Bull. Korean Chem. Soc. 1999, Vol. 20, No. 2 NotesDoxorubicin shows a wide spectrum of activity for solidtumors such as sarcomas, adenocarcinomas and melanomas,but its strong side effects including myelosuppression,extravasation reaction and cardiotoxicity have been a seriousproblem.


Abstract Aims Paediatric inflammatory multisystem syndrome– temporally associated with SARS-CoV-2 (PIMS-TS) is a novel hyperinflammatory condition that most commonly presents with an acute abdomen. Here we present a case of PIMS-TS mimicking appendicitis and a review of the literature with a proposed protocol for managing abdominal pain in patients with recent SARS-CoV-2 infection. Results An 8-year old girl presented with suspected appendicitis. She underwent a day case open appendicectomy with normal appendix confirmed on histology. Unfortunately, she re-presented the following day with persistently high fever and was investigated for post-appendicectomy complication. She was started on intravenous antibiotics. MRI of abdomen and pelvis showed no collection but evidence of lymphadenopathy. On post-operative day four she was transferred to the tertiary centre PICU for specialist management of suspected severe PIMS-TS. Common abdominal radiological findings in PIMS-TS include ascites, bowel wall thickening and mesenteric inflammation. In addition, CRP and ferritin have been found to be significantly higher in PIMS-TS. White cells may be raised with neutrophilia and lymphopaenia. In addition, highly deranged inflammatory markers in the context of a normal abdominal imaging are more consistent with PIMS-TS than appendicitis. We propose anyone with these findings is considered as having PIMS-TS and requires urgent imaging including combined senior surgical and paediatrician review. Conclusion PIMS-TS may present mimicking acute appendicitis and given the severe cardiac compromise that can develop in patients with PIMS-TS is it important to avoid unnecessary general anaesthetic and abdominal surgery where possible. Our proposed protocol could help reduce unnecessary abdominal surgery in these patients.


ABSTRACT The exhibition UNSETTLED: Colonial Ruin in the Flinders Ranges is a critical examination of settler-colonial nostalgia in the Flinders Ranges, within an artistic context. The project is underpinned by a partnership with the State Library of South Australia (SLSA) and the Adnyamathanha Traditional Lands Association, and it was exhibited at the SLSA in Adelaide, March–May 2017. Spread across the SLSA Institute Gallery, on the videowall in the Spence Walkway, and on the Storywall outdoor architectural projection, the exhibition consists of a range of photographic and video art works alongside portrait images of Adnyamathanha people taken in 1937 at the Nepabunna Mission by Charles Mountford, and video interviews with descendants of the people in the portraits. In this article, we discuss the components of the exhibition and its artistic and curatorial rationale and, in so doing, propose a series of responses to the key question that guided our activities on this project: What strategies and practices can non-Aboriginal artists employ to question the dominance of settler-colonial nostalgia in Australia?


Mechanical properties of Hastelloy C-276 substrate with different pre-treatment were investigated. Discontinuous yielding was observed in the solution treated substrate after annealing at the maximum process temperature of IBAD and ISD. In the smooth rolled substrates, yield strength higher than 1 GPa can be attained and even after annealing continuous yielding can be maintained. Annealing enlarges elastic limit by pinning of the mobile dislocations. Microstructure observation using transmission electron microscopy shows that two kinds of candidates for the pinning site of the dislocations exist such as precipitates and short range ordering region in the discontinuous yielding substrate. Improvement of strain at quenching was confirmed by utilizing continuous yielding substrate with higher elastic limit.


A woman talks about her Ala Wai property and home; childhood activities; Royal Hawaiian and Moana hotels; boating and crabbing; Ala Wai fishermen; beach boys and beach clubs; rivalry between Roosevelt and Punahou high schools; December 7, 1941 attack and effects on family; marriage to ensign; chicken raising; introduction of frogs to Waikiki by father; parents' two-story apartment building and cottage rentals; husband's passing; support of two children; Jefferson School; changes in Waikiki; and mother's loyalty to Waikiki.


In a sprint start, the athlete takes up a position with their hands just behind a line, arms vertical, feet generally placed about a shoe length apart, and the hips rising above the line of the head. Mistakes in this position influence the ex- ecution of the low-sprint start, and can drastically influence the initial running speed and acceleration achieved by the athlete. Common mistakes occur due to the misconception that athletes must also lean forward, bringing the shoulders ahead of their hands and putting pressure on them. A standard approach to identify sprint start mistakes is to use a stick or weighted string to drop down from the shoulders. The effective implementation of this approach depends on the coach's experience and remains a significant challenge. In this study, a three-dimensional motion capture system with the Vicon® Plug-in-Gait model was used to characterize the kinematic parameters that influence the execution of low-sprint start in six high-performance athletes. The main kinematic parameters are reaction time, stride length, and stride time. The obtained results demonstrate the potential utility of a three-dimensional motion capture system to assess the kinematic parameters of low-sprint start in high-performance athletes.


Using a large firm level dataset, that covers 18 European countries in the 2006-2014 period, I develop an empirical approach in the spirit of Rajan and Zingales (1998) in order to study whether and to what extent the credit cycle influences the efficient allocation of resources across firms. I document that a higher availability of credit leads to a decline in both capital and labor misallocation, suggesting that, when credit is above its trend, the additional funds flowing in the economy reduce financial frictions, allowing financially constrained but productive firms to implement their projects. The estimated effect explains 7.8% and 5.8% of the variation in the within-sector dispersion in the marginal revenue products of capital and labor respectively, and it is consistent with respect to a wide range of robustness checks. It is larger when evaluating exclusively the manufacturing industry or countries with relatively small domestic credit markets, while tends to disappear for financially developed economies.


Experimental pleurisy in rats was induced by intra-pleural injection of 0.1 ml 2%-λ-carrageenin, as previously reported (1, 2) . The accumulation of pleural fluid continued until the peak volume of 4 ml at 19 hrs after carrageenin injection, involvemen of plasma kallikrein-kinin system in the early phase of the pleurisy was proved with the following series of experiments.(1) The levels of prekallikrein, HMW-and LMW-kininogens in plasma and pleural fluid were measured at 1, 3 and 5 hrs after carrageenin injection. The level of HMW-kininogen in pleural fluid was extremely low, whereas LMW-kininogen level was not reduced. The level of prekallikrein was also low in the pleural fluid, about 1/10 of that in plasma. As the plasma levels of these components in pleurisy rats were not significantly different from those in control rats, the above results suggest that plasma kallikrein-kinin system could be activated at the inflammatory site, but not in circulating blood.(2) Pretreatment with 10 mg/kg intraperitoneal captopril enhanced significantly the accumution of pleural fluid as well as dye exudation.(3) Pretretament with bromelain, 10 mg/kg intravenously, which was shown to exhaust HMW-kininogen and prekallikrein, suppressed the accumulation of pleural fluid and dye exudation, significantly at 1, 3 and hrs after crageenin.


The fibrous xanthoma is a somewhat unusual tumor which has never before been reported in the larynx. A fibrous xanthoma involving the laryngeal surface of the epiglottis was excised with a supraglottic laryngectomy and neck dissection, and the patient has done well. Although only approximately 1% of these tumors prove to be malignant by metastasizing, there are no reliable histologic criteria for determining whether this tumor will behave in a malignant manner. Since these tumors recur locally if not adequately excised, the treatment of choice is adequate excision, including a margin of normal tissue.


It is axiomatic that India requires to self sufficient in the design, development and production of aircraft both for civil and military use, and not, as she is at present, remains entirely dependent on foreign sources. This requirement is keenly felt in the field of defence, since it is appreciated .that the growth of the Armed Forces of a country, in fact their very existence in peace and war, is in modern times directly related to the industrial potential of that country to produce weapons of war. If the two are not properly balanced the Armed Forces would be quite ineffective in fulfilling their role of defending their country in time of emergency.


Recent high-throughput techniques (e.g. yeast-two- hybrid) have generated large-scale protein interaction data, which are believed to be highly noisy. Assessing the reliability of these interactions becomes an important task in proteomics. In this paper, we first label the protein interaction network by Gene Ontology (GO) annotations, and then identify reliable interactions based on the statistical significance of these semantic labels. Experimental results show that our proposed reliability measure can be used to detect reliable interactions with a better performance.


Abstract A novel cucurbit[6]uril (CB[6]) mediated alginate physical hydrogel bead was prepared for the first time, which is based on the electrostatic attraction and ion-dipole interaction between sodium alginate and CB[6]. These alginate/CB[6] gel beads are useful in controlled drug delivery and other biomedical applications. The potential of alginate/CB[6] gel beads as carrier for 5-Fluorouracil (5-Fu) was studied in this paper. The properties of alginate/CB[6] gel beads were studied by FT-IR, XRD and TGA. The process of the formation of alginate/CB[6] gel beads was recorded by Digital cameras. The external morphology of the dried beads were observed using SEM. Alginate/CB[6] gel beads first was formed as a thin film on the surface of the alginate solution droplet, holding its spherical shape. The color of the alginate/CB[6] gel beads changed from almost colorless to white with the increase of gel time, and also the beads became small and compact. The dried alginate/CB[6] gel beads were about 900-1000 μm, irregular spherical and the surface of dried beads showed a corrugated surface having a uniform distribution of regular nodules and cavities.


The article treats the public opinion in Soviet Russia and of the Russian Emigration in one of the crucial moments of the Russian political history at the turn of 1922-1924,when V. Lenin, the leader of the Russian bolshevist revolution, because of his illness growing progressively worse, was excluded from politics. His inevitable death caused different forecasts, hopes and expectations concerning Lenins political heir. The article is based on the archival documents (including unpublished archives) and memoirs.


Waves capable of propagating on arrays of capacitively loaded loops (stacked axially or arranged in a planar configuration) were predicted in [1], treated in more detail for the twoand three-dimensional cases in [2] and proven experimentally in [3]. The aim of the present communication is to show that MI waves belong to the family of linear waves not only when propagation in a homogeneous medium is considered but also in respect of properties like reflection, refraction and diffraction, a set of phenomena which were already investigated for coupled waveguide arrays. The best testing place for examining these properties is a 2-D array for the reason that the phenomena are not there in 1-D, and a 3-D approach is unnecessarily complicated. Answers are given to the following problems: (1) The conditions under which it is possible to excite a wave possessing a single spatial frequency. (2) The effect of an obstacle (an element with different parameters) in an otherwise homogeneous array when a wave with a single spatial frequency is incident upon the obstacle. (3) Distortion of a spatial distribution impressed at one end of the array when it reaches the other (matched) end. (4) The reflection and refraction at the boundary of two homogeneous media, i.e. when the arrays on the two sides of the boundary have different parameters. (5) Analogy with transverse electromagnetic waves: the conditions for defining an equivalent wave impedance and refraction index. It is also shown by using an alternative approach (an equivalent coupling coefficient is derived between any two 1-D waveguides instead of assuming coupling between individual elements) that the analogies between the properties of coupled capacitively loaded loops and those of coupled waveguides [4] are very close.


The background of this research is motivated by the high number of educated unemployment in Indonesia. This study aim to describe: 1) learning outcomes of pastry courses, 2) learning outcomes of bakery courses, 3) student entrepreneurial interest, 4) analyze the relationship between learning outcomes of pastry courses and entrepreneurial interest of family welfare education study program students majoring in culinary arts, 5) analyze the relationship between learning outcomes of bakery courses and entrepreneurial interest of family welfare education study program students majoring in culinary arts, 6) analyze the relationship between learning outcomes of pastry and bakery courses with entrepreneurial interest of family welfare education study program students majoring in culinary arts. This type of research is quantitative with a correlational approach. The research population was 196 students of family welfare education study program majoring in culinary arts class of 2018 and 2019. The sample is 66 people taken by Proportionate Random Sampling. The primary data collection technique uses a questionnaire distributed is measured using a likert scale. Then for secondary data using learning outcomes in pastry and bakery courses. The analysys requirement test was carried out with normality test and linearity test, then test the hypothesis using pearson product moment and multiple correlation coefficient analysis, and then test the significance of the\ correlation with the t test using help of SPSS 24.00 version. The results showed that: 1) learning outcomes of pastry courses students is in the excellent category (34,8%), 2) learning outcomes of bakery courses students is in the very good category (51,5%), 3) entrepreneurial interest students is in the medium category as many as 37 students, 4) there was a positive and significant relationship between learning outcomes of pastry courses and entrepreneurial interest of family welfare education study program students majoring in culinary arts with a correlation value of rxy0,621 means that it has a strong level of relationship, 5) there was a positive and significant relationship between learning outcomes of bakery courses and entrepreneurial interest of family welfare education study program students majoring in culinary arts with a correlation value of rxy 0,701 means that it has a strong level of relationship, 6)there was a positive and significant relationship between learning outcomes of pastry and bakery courses with entrepreneurial interest of family welfare education study program students majoring in culinary arts with a correlation value of 0,000 < 0,005.


ABS TRACT Objective: This study aimed to assess two oxidative stress (OxS) markers, thiol-disulfide (TD) homeostasis and ischemia-mod- ified albumin (IMA), in newly diagnosed metastatic pancreatic cancer (PC) patients. Material and Methods: This was a prospective case-control study including two groups: 30 cases each of histopathologically confirmed metastatic PC patients and healthy controls. Serum TD and IMA levels were measured and compared in both groups. Moreover, the association between TD and IMA levels, as well as overall survival (OS) in the patient group, were investigated. Results: Both native thiol (NT) and total thiol (TT) levels significantly decreased in the patient group than in the control group (p=0.016 and p=0.009, respectively). However, disulfide (D) and IMA levels were similar between the two groups (p=0.056 and p=0.068, respectively). Both the D/NT and D/TT ratios were significantly higher in the patient group (p=0.005 and p=0.004, respectively) than in the control group. Additionally, no association was observed between IMA, TD homeostasis, and OS. Conclusion: Our results showed that increased OxS levels affected PC progression. With the development of newer targeted therapeutics for OxS, the progression of PC in individuals with higher genetic risk may be prevented.


The higher integrability for weak solutions to obstacle problems associated with A-harmonic equation for the differential forms has been proved.


We survey the archimedean representations and Langlands parameters corresponding to holomorphic Siegel modular forms of degree 2. This leads to a determination of archimedean local factors for various L-functions and all vector-valued weights. We determine the Hodge structures that correspond to holomorphic Siegel modular forms and clarify the relationship with four-dimensional symplectic artin representations.


Spaceborne remote sensing with synthetic aperture radar (SAR) has become an essential source of high-resolution and continuous Earth observation. Modern satellites like the German TerraSAR-X system provide state-of-the-art radar images with respect to operating flexibility and imaging quality. The outstanding performance of TerraSAR-X image products is achieved by an innovative calibration approach that minimizes systematic antenna and instrument characteristics. The active phased array X-band antenna is fed by 384 transmit/receive modules for electronic beam steering and shaping in the azimuth and elevation direction. The flexible radar instrument hosts an internal calibration system which guarantees the high radiometric stability of all SAR products. New techniques for antenna performance control have been successfully implemented, setting a high standard for next-generation SAR missions. This paper summarizes all essential calibration results of TerraSAR-X that cover internal instrument behavior. Furthermore, we give an outlook on the required bistatic calibration techniques for the future TanDEM-X mission that faces additional performance challenges when calibrating two TerraSAR-X satellites flying in close formation.


Significance
 However, he will lack the commodity boom-related revenue that fuelled such programmes. Bolivia has been hit hard by the COVID-19 pandemic; GDP is forecast to contract by between 5-8% in 2020 amid increasing fiscal and external deficits and declining foreign reserves.

 Impacts
 Economic stress in key industries will carry over to the financial sector, potentially triggering a need for liquidity support.
 Insecurity could weigh on foreign investment, especially if anti-MAS protests endure or unrest develops over issues such as unemployment.
 A weaker hydrocarbon sector will hit growth, particularly if the country fails to diversify its economy.


We conducted land-based counts of harbor seals (Phoca vitulina richardii) and collected related environmental data at Tugidak Island (Gulf of Alaska, 1994-2000) and Nanvak Bay (Bristol Bay, 1990-2000) to estimate population trends and identify factors influencing counts. At Tugidak Island, the seal population declined substantially during molting from 1976 through the 1980s, stabilized in the early 1990s, and increased at a moderate rare (3.4%/yr, CI: 1.0%-5.8%) from 1994 to 2000. Pups and all seals ashore during pupping increased at higher annual rates of 5.4% (CI: 2.2%-8.8%) and 8.3% (CI: 4.5%-12.3%) from 1994 to 2000 at Tugidak Island. At Nanvak Bay seals declined in abundance between 1975 and 1990 but increased during the 1990s at 9.2%/yr (CI: 7.2%-11.3%) during pupping and 2.1%/yr(CI: 0.6%-3.6%) during molting. Date and time-of-day were significant covariates in all analyses. Factors that led to declines at Tugidak Island and Nanvak Bay have seemingly abated sufficiently such that these populations are currently increasing, though still greatly reduced from the 1970s. Index sites are useful adjuncts to aerial surveys, providing survey-related information not always available from aerial counts, which is useful in survey design and data analysis.


The objective of this research is to develop a proposal for material
As a technological tool to generate learning
In the students of the subject of Systems Analysis and Design of the
Educational Program of Engineering in Control and Computation, in the Sciences Area
Basic and Engineering of the Autonomous University of Nayarit. The information is
Obtained through a diagnostic tool that allowed the identification and evaluation of
Channels commonly used by students to learn through resources
Technology, this will serve as the basis for the design of digital educational materials.
The treatment of the data for validation of the diagnostic instrument was through the
IBM SPSS Statics 19 software, using the Cronbach Alpha coefficient.


Detecting neutrinos and photons is crucial to identifying the sources of ultrahigh-energy cosmic rays (UHECRs), especially for transient sources. We focus on ultrahigh-energy gamma-ray emission from transient sources such as gamma-ray bursts, since >EeV gamma rays can be more direct evidence of UHECRs than approximately PeV neutrinos and GeV-TeV gamma rays. We demonstrate that coincident detections of approximately 1-100 events can be expected by current and future UHECR detectors such as Auger and JEM-EUSO, and the detection probability can be higher than that of neutrinos for nearby transient sources at < or approximately equal to 50-100 Mpc. They may be useful for constraining the uncertain cosmic radio background as well as knowing the source properties and maximum energy of UHECRs. They can also give us more than 10(4) times stronger limits on the Lorentz-invariance violation than current constraints.


(57) Abstract: Mathematical regularization selected by signature extracted from representation and identified data element data, by a system adapted to access the elements via the reference by signature, of interest to those who query method that can be rendered through the appropriate language translators are provided. The language translator of this interest, may be included text-to-speech translator, it is programmed simplified text representation so as to match the elements mapped stored audible representation, and HTML representation. Another feature of the present invention, the method has been identified in the selected element, it is selected by the customized selected elements for rendering suitable for the desired context and critical appropriate language translators customization and further comprising a further particular of the elements.


Age, growth, gonadosomatic index and condition factor of poor cod, Trisopterus capelanus were evaluated from 593 specimens collected in Edremit Bay, the northern Aegean Sea between the years of March 2015 and February 2016 by the hauls of trawls. Total length ranged between 10.7-19.8 cm and 9.6-17.0 cm while weight varied between 9.34-95.59 g. and 8.13-51.45 g. in females and males. The male and female ratio was 1:0.42 (M:F) in the favor of males. The von Bertalanffy growth equations (in length) were found as Lt= 23.5 (1-e) for all individuals. Length-weight relationships were found to be W=0.0089L (R=0.9299), W=0.0112×L (R=0.9125), and W=0.0087L (R=0.9347) for females, males and combined sexes, respectively. As the determination b values are not statistically significant from 3 (t test, p>0.05), isometric growths were observed for all samples. The condition of the fish increased during autumn. A long spawning season (about 4-5 months) in late winter-early spring occured in the population. Analysis of the diet composition showed that poor cod is carnivourus and the food composition of T. capelanus consists of mostly crustaceans as Alpheus glaber and Liocarcinus sp. Poor cod has an economic value for Turkish Seas and it is also important in the view of biodiversity.


This article mainly examines the content of the three decisions made by the Standing Committee of the National People's Congress authorizing the State Council legislation. It points out under the present social conditions of deeply -developing reform and legislative techniques, there exist obvious flaws in the three decisions. So it is advised that the Standing Committee of the National People's Congress should formulate definite rules in authorizing the State Council, according to"the law of legislation".


Based on the production system of high functional plastic production areas, the authors design an information acquisition system based on OLE for Process Control (OPC) technology. The system achieves the bottom information and uploads to the management layer. It uses a combination of Ethernet and serial communication to connect field equipment. Through hardware manufacturer provides the OPC Server interface to save real time information of the production equipment in real-time database of the industrial configuration software. On the basis of this, the upper application system is flexible to access the field devices through OPC Client, gathering and managing real-time information. The production practice shows that the system is not only safe and reliable communication, rapid data collection and processing, but also constantly update and extend the functionality in the future, to satisfy the business enterprises to the higher requirements of the production.


Taking a certain type of excavator as the research object, the 3D models of its working device were established and assembled by 3D design software Pro/E. And then the 3D models were imported into dynamics simulation software ADAMS to build the virtual prototype system after adding constraints and load. Through simulation analyzing on working device during one work cycle time, the mainly articulated point's load stress curves were obtained for working device. Thus proved its movement characteristics in line with the actual working condition, which provides the theory reference of design and analysis and uses as a design basis for hydraulic excavator working device.


The influence of high-pressure gaseous hydrogen environment (15 MPa) on the fatigue crack growth in forged Ti-6A1-4V at room temperature is investigated. It is observed that the fatigue crack growth (FCG) rate is fluctuating at 20 ≤ ΔK ≤ 26 MPa√m, and increase drastically at ΔK > 26 MPa√m in hydrogen environment. The effect of hydrogen on the FCG rate is dependent on the stress intensity level (ΔK). Detailed fractographic analysis of the fracture surfaces is performed at different ΔK using field emission scanning electron microscope (FE-SEM). The differences in appearance of fracture surfaces in air and hydrogen are discussed.


During these last seasons, the drought has caused losses of 50 % of the production of potato in several countries of Centro America. The Hydric Relative Contents (CHR) as the Hydric Relative Velocity (VHR) is important index to determine tolerant varieties to drought. The experiments were developed in the Institute of Investigation in Tropical Roods (INIVIT). To the 15 days of stress for deficit hydric (50 to 65 days after the plantation date), the minor decrease in the CHR showed were variety Atlas with 27.12 %, on the contrary, the bigger value was reported in the variety Armada with 43.38 %. The varieties that showed minor values in the rate of Hydric Relative Velocity (VHR) were Atlas and Maranca, with 1.80 and 2.00 % per day respectively.


Middle Judaism was characterized by the passage from a religion based on sacrifices to two new religions without sacrifices, namely Christianity and Rabbinic Judaism. The main signs of this passage are the following: the attention was shifting from the sacrifice itself to the attitude and moral character of the one sacrificing, especially in Hellenistic Judaism; the idea that a person's voluntary sacrifice could induce God's intervention in favor of the people, even to the forgiveness of sins. Some acts, ablutions for instance, were substituting sacrifices as purification rites which were first attributed only to sacrifices. It is even possible that John's baptism was intended for this purpose. There was also strong criticism on sacrificial rites practiced at the Temple in Jerusalem and a growing devotion to prayers and the reading of the Torah. The Temple's destruction in 70 just accelerated an ongoing process.


Introduction African Americans Arab Americans Chinese Americans Cuban Americans East Indian Americans Filipino Americans German Americans Haitian Americans Irish Americans Italian Americans Japanese Americans Jewish Americans Korean Americans Mexican Americans Vietnamese Americans Index


Deep neural networks can obtain effective hierarchical representations, which make them perform well in image recognition and speech recognition. However, the disadvantages of deep learning relying on large-scale annotation data also limit its development. To this end, a multi-layer convolutional neural network based on knowledge graph prior knowledge is proposed in this paper, which acquires text features from finer granularity, and using the existing prior knowledge which increases granularity information to enhance the semantic information of the text, and to reduce the dependence of the model on large-scale samples. At the same time, it can reduce the over-fitting problem of the model, and improve classification accuracy. This model performs well in several large data sets. By introducing prior knowledge to TextCNN, a classical deep neural model, it has also verified the validity of using prior knowledge through experiments.


The article attempts to introduce the reader to some issues concerning a new phenomenon in literature – liberature – though the phenomenon is deeply rooted in the past. My intention is to show and discuss not only the basic tenets of liberature, such as the perception of the work as an integral entity in which the word and the space merge into indivisible wholeness, but also to present a particular evolution of various literary forms that eventually effected in an inception of a new literary current. The core element of this process is to emphasize and highlight the coexistence of the form and the content, i.e., something that was already present in visual poetry stemming from the ancient and medieval times and became increasingly powerful in the output of authors associated with the twentieth-century avantgarde movements. The "total" perception of literature has been most interestingly expressed in the output of authors-liberates: Zenon Fajfer, Katarzyna Bazarnik and Radoslaw Nowakowski (both authors and theoreticians of liberature), whose profiles are outlined in the present article.


People interact each and every day in order to communicate with one another, irrespective of their social, cultural or religious background. The phenomenon of communication is intrinsically linked to the preservation and evolution of the human existence. Humans exchange messages verbally at the interpersonal level and communicate "silently" through body language. They use a universal language that unites people and contributes to a harmonious emotional togetherness despite the peculiarities and difficulties in understanding. There are indeed cases where communication is particularly difficult due to the absence of a common verbal code and in this case communication is mostly based on non-verbal signals. The current thesis was drafted by reason of the recent war in the neighboring country of Syria. The war in Syria has been raging for over five years now and has resulted in the influx of thousands of immigrants in our country, especially in the islands of the northeast Aegean. The aim was to investigate whether non-verbal communication was used between the educators and the children of Syrian refugees, who were settled temporarily in a concentration camp in city of Mytilene. Moreover, the forms of non-verbal communication between them were investigated, as well as whether this communication was affected by the gender of the educator or the refugee. Lastly, the current thesis seeks to examine whether the use of a non-verbal code is sufficient for a complete communication. The survey method used was the qualitative method. More specifically, the data collection tools used was the random and casual observation and the semi-structured interview. Fifteen refugee children were observed in total, 8 girls and 7 boys, aged 5-10 years, who were allocated in different places: a hotel, which was used as a reception center and as a care center for refugees and a camp, which was properly adjusted to accommodate the refugees' temporary stay. Fifteen educators were observed and then interviewed for this study. The educators, 9 women and 6 men, aged 25-40 years, had a 3 to 12 months working experience in the reception and accommodation of refugees. The data of the survey display the dominance of nonverbal communication between refugees and educators, especially were verbal communication was very limited. The gender of the educators initially seems to affect the relationship between the educators and the refugees, but this obstacle is soon overcome. Respectively, while the gender of the refugee children seems to impair communication at first, along the way prevail the power and the need for communication. However, quite different is the case of children with post-traumatic problems, who seem to need more time to overcome these problems, in order to conduct themselves normally and to trust their educators. To conclude, the close relationship between the verbal and the non-verbal code is established, owing to the fact that verbal and nonverbal communication comprise an integral unit for a complete communication. Subsequently, suggestions for improving the communication between refugees and educators are provided.


Markov modelling deals with discrete event systems in which events happen completely at random.
 The resulting Markovian systems can often be analyzed analytically. In this session, we show how to use the available packages, and what methods can be employed to find transient and steady state results. It turns out that Markov modelling is extremely convenient to analyze systems with very few state variables.


Fertility expectations during 1964 were remarkably similar in distribution to those previously reported for 1962 and 1963. Tables 1 and 2 indicate that the frequency distributions of total number of expected children and the mean number of live births and the mean number of expected children are virtually unchanged in 1962 1963 and 1964 for both the total and the white population. (excerpt)


We examined support systems on the health of those bullied at work. Our findings showed that bullied victims experience more stress, worse health, less satisfaction, and higher intentions to leave while organizational support systems help to minimize this effect of bullying on victims.


Insect pests cause irreversible damage to natural history, ethnographic, textile and general collections in museums. This book identifies the problems and gives practical advice on the detection, prevention and control of insect pests in museum stores. The major pest species are illustrated and described together with strategies for prevention and control of damage by integrated use of physical and chemical methods. Coverage of the benefits and limitations of insecticides is intended to encourage their safe and effective use in museums.


Background : Across the globe, trauma remains as one of the leading causes of morbidity and mortality. 25% of trauma mortalities can be attributed to blunt thoracic trauma. Myocardial contusions are perhaps the most uncommon injury reported after blunt thoracic trauma and no gold standard has been established to diagnose such patients. Patients with cardiac contusions have non-specific signs and symptoms which can easily be masked by other diagnoses like hemorrhagic shock, tension pneumothorax and tamponade. Case Report : A young male with blunt trauma presented to the emergency after a road traffic accident and succumbed due to myocardial contusions. Here we describe how we came to the diagnosis of myocardial contusions. Conclusion : It is imperative for emergency physicians to recognize myocardial contusions in blunt thoracic injuries early to avoid unfavorable outcomes.


In order to elucidate the defect model in the spinel ferrites, the nonstoichiometry in magnetite and its solid solutions, (Fe1−yAly)3−δO4, (y=0.0, 0.25, 0.33), was determined at temperatures between 1300 and 1550 °C. The redox equilibria between Fe2+ and Fe3+ and the site preference of Fe2+, Fe3+, and Al3+ ions and cation vacancies were investigated and sixteen kinds of models were examined. The "best" model was chosen using the criteria that the dependence of the equilibrium constant on δ and y should be as small as possible. In the selected model, Fe2+ ions on B-sites are regarded as electron donors in a narrow 3-d band formed by Fe ions in B-sites. The following expression for the defect equilibrium was found:\frac23(1−y)FeA2++\frac2(2−3y)3(1−y)eB−+\frac12O2(g)\ightleftarrows\frac23(1−y)FeA3++\frac14VA+\frac12VB+OL2−.


Includes descriptive metadata provided by producer in MP3 file: "Listen to a podcast of Robin Smith, Geisel Award committee member, and Dean Schneider, Newbery Award committee member, discussing their experiences on the committees and how and why books are chosen for these awards."


Aspect-level sentiment analysis (ASA) aims at determining the sentiment polarity of specific aspect term with a given sentence. Recent advances in attention mechanisms suggest that attention models are useful in ASA tasks and can help identify focus words. Or combining attention mechanisms with neural networks are also common methods. However, according to the latest research, they often fail to extract text representations efficiently and to achieve interaction between aspect terms and contexts. In order to solve the complete task of ASA, this paper proposes a Multi-Attention Network (MAN) model which adopts several attention networks. This model not only preprocesses data by Bidirectional Encoder Representations from Transformers (BERT), but a number of measures have been taken. First, the MAN model utilizes the partial Transformer after transformation to obtain hidden sequence information. Second, because words in different location have different effects on aspect terms, we introduce location encoding to analyze the impact on distance from ASA tasks, then we obtain the influence of different words with aspect terms through the bidirectional attention network. From the experimental results of three datasets, we could find that the proposed model could achieve consistently superior results.


Let G be a compact Lie group and R an orthogonal representation of G acting on R". For any irreducible unitary representation it of G and vector c in the representation space of it define %(it, v) to be those functions in S(R") which transform (under the action R) according to the vector v. The Fourier transform 5 preserves the class S(w, v). A Bochner identity asserts that for different choices of G, R, it, v the Fourier transform is the same (up to a constant multiple). It is proved here that for G, R, m, v and G', R', it', v' and a map T: %(it, t>)-> %(tt', v') which has the form: restriction to a subspace followed by multiplication by a fixed function, a Bochner identity ). From this result all known Bochner identities follow (due to Harish-Chandra, Herz and Gelbart), as well as some new ones.


Determination of aerodynamic damping coefficients has always been difficult due to the dynamic nature of measurements for both forced and free methods. Although aerodynamic damping identification is available since the 1960s, this testing capability is not available in most of the high-speed wind tunnels due to its complexity, although the aerodynamic damping coefficients are needed for every aerospace vehicle. Herein are presented the development of the rig for roll damping determination, which uses both free and forced methods in the working cycle; the calibration process using the basic Finner model with reference data; and the experimental results obtained. Also, considering the challenges for computational fluid dynamics to match the experimental results, numerical results are presented for the calibration points required for interpolation of the roll damping coefficient along a Mach number range. The calibration points cover all regimes from subsonic to supersonic at Mach numbers ranging between 0.4 and 3.5. Conclusions are presented, focusing on the comparison between forced and free methods, as well as the rotation direction, considering the flow deflection that is increasing the level of uncertainty.


Background: Disclosure is a key process in the management of sickle cell clients. This process if done well results in positive holistic ways of managing clients. However, if not handled well it can affect the client and the entire family both psychologically and emotionally, thus affecting the client's management. There is still an extensive debate regarding when and how to disclose genetic data to research participants in studies with a genetic component. Consequently, researchers and research ethics committee continue to struggle with the questions on whether research protocols should adopt provisions about disclosure of genetic data and if so, how it should take shape. Objectives: The objectives were to identify the process of disclosure of sickle cell disease results, to determine the perception on the adequacy of disclosure process and to determine the ethical consideration in the disclosure process. Methods: This was a cross sectional, qualitative study conducted at a Hemato-oncology clinic in a teaching hospital using key informant interviews and in-depth interviews. Results: A total of (46) research participants and (5) research staff were interviewed. In view of disclosure process, the World Health Organization (WHO) six-step protocol was not adhered to and thus breach of confidentiality and fairness principles. Results showed that veracity as a principle was not addressed, since there was no specific team assigned to disclose results in the clinic, evidenced by 40/46 participants given results by the doctor alone. Out of 46 participants, 38 reported that they did not get emotional support, thus negating the principle of non-maleficence. On respect for persons, 36/46 participants reported that disclosure of information was inadequate. Confidentiality was maintained as reported by 44/46 participants and the principle of justice was observed since 40/46 reported that their children received medication and showed great improvement. Most staff (3/5) believed breach of disclosure process was due to huge workload. Conclusion: The study found that there was no consensus on who and how to disclose sickle cell disease results at the hemato-oncology clinic. The six-step WHO protocol was not adhered to and parents/guardians felt that the information given was inadequate. Ethical issues of beneficence, autonomy, veracity, non-maleficence and respect of persons were not well addressed. However, confidentiality was well observed.


Abstract Objective: Whereas research suggests young women's beliefs about breast cancer (susceptibility/severity) and its early detection (barriers/benefits) reliably distinguish breast self-examiners from nonexaminers, this study assessed whether these impressions are interreliant, especially in the context of familial risk. Participants: The sample comprised over 200 female undergraduates from a university in England, United Kingdom. Methods: Participants completed a self-administered survey on their attitudes concerning breast cancer and early detection. Data were analyzed using logistic regression analysis. Results: Nonexaminers were distinguished by a combination of greater perceived hindrances to self-examinations and stronger appraisals of breast cancer severity, and also by a permutation of fewer perceived benefits in self-examinations and lower perceived susceptibility to breast cancer. The latter interaction persisted after accounting for family history. Conclusions: Interwoven attitudes may depict sophisticated efforts on the part of nonexaminers to justify inaction. Clinical implications for college health providers are considered.


Aim : The aim of the study was to compare the efficacy of Diffusion weighted imaging in predicting the histology of intracranial neoplasms and to correlate with WHO grading. Methods and Materials : This prospective study was performed in 41 patients with intracranial tumours.Diffusion gradients and ADC maps were calculated within the tumor, the peritumoral region, and the contralateral normal appearing white matter .The ratios were calculated by dividing the maximum value in the tumor and in the peritumoral region by the value in the contralateral normal-appearing white matter. For statistical analysis Student independent t-test and ROC curve analysis was performed. Results: The difference in the mean ADCt ratios of high and low grade gliomas were statistically significant. To identify high-grade gliomas, a cut off of < 1.217 for ADCt yielded 70 % sensitivity and 20 % specificity. ADCt and ADCp ratios showed no significant difference to differentiate between high grade glioma and metastasis. Conclusion: Diffusion weighted images showed very good diagnostic accuracy in grading glial tumors, however had limitation in differentiate between high grade glioma and metastasis.


The ISIS facility, based at the Rutherford Appleton Laboratory in the UK, provides intense pulsed neutron and muon beams for condensed matter studies. As part of the facilities upgrade and refurbishment program, the 1MJ storage choke which forms part of the main magnet power supply system, will be replaced with a number of smaller units. The present storage choke, which consists of a split secondary winding transformer, is incorporated into a series-parallel resonant circuit known as the 'White circuit' [1]. This circuit ensures that each magnet receives identical currents, but is not subjected to excessive voltages. Although the storage choke is essentially a transformer, its secondary magnetising inductance is relatively low and a precisely defined value. This paper discusses the design and development of ten smaller units which will eventually replace the present equipment, and the testing of a one fifth scale model, which will be used to prove the technology.


Glass‐ceramics with high performance and high crystallinity was produced using rare earth blast furnace slag (REBFS) as the primary raw material, along with composite nucleating agents Fe2O3 and Cr2O3. The migration pattern, distribution characteristics, and solidification properties of heavy metals in glass‐ceramics were investigated by the controlled heat treatment. The findings indicated that the heat treatment temperature has a significant effect on the distribution and color of heavy metals in glass‐ceramic. In the crystallized glass‐ceramic, spinel acts as the crystal core for heavy metal solidification, Cr, Cu, and Mn can exist stably in the spinel by the solid solution. The glass‐ceramic was expected to be used as a decorative building material.


In this paper we study the impact of phonetic annotation precision on the accuracy of a state-of-the art ASR (automatic speech recognition) system. This issue becomes important especially if we want to port the system to a new language without spending much time by collecting, checking and annotating a large amount of acoustic data in the target language. First, we describe a series of experiments that demonstrate how inaccurate annotation influences word error rate of a gaussian-mixture model and deep-neural net based ASR. Our results show that even significantly inaccurate annotations allow to achieve fairly good results. On the other side, if we want to get really good performance, we should assure that the annotations are as precise as possible. Therefore, we describe methods that can do most of the annotation work in an almost automatic (iterative) way with a high precision. We demonstrate them on an ASR system that is being adapted from Czech language to Polish. We provide results achieved on Polish GlobalPhone and Clarin speech databases.


Asthma SEREVENT is indicated for long-term regular treatment of reversible airways obstruction in asthma (including nocturnal asthma and exercise-induced asthma) in adults and children who are receiving inhaled or oral corticosteroids. SEREVENT should be used only as an adjunct to corticosteroids in the management of asthma. SEREVENT should not be used in the treatment of acute asthmatic symptoms, or in patients whose asthma can be managed by occasional use of short-acting beta-2 agonists. Chronic Obstructive Pulmonary Disease (COPD) SEREVENT is indicated for long-lasting (12 hour) bronchodilation in adults with reversible airways obstruction due to COPD.


Objective: To observe the clinical effect of fixed cantilever prosthesis on the missing second mandibular molars. Methods: Twenty five patients who received cantilever fixed partial dentures to restore the lost second mandibular molars with the second mandibular premolars and the first molars as abutments were checked clinicallyand radiographically during 1995-2001. Results: Of the 25 patients, 2 failed for the loss of retention,1 for the fracture of the end abutment. Conclusions: With the appropriate design of pontics, and with the favourable abutment teeth and supporting periodontium, fixed cantilever prosthes?s can be used to restore the lost second mandibular molars.


Resumen en: The autor thinks the reflextions of L6vi-Strauss about the myth pro-duction and his passion finding models to understand the indoameri-can myths in hundr...


Purpose – The purpose of this paper is to describe how to improve magnetic pick up sensor for detection of weak magnetic field. A magnetic marker detection system, built using hall sensors is improved by providing ferrite cores as back yoke to obtain benchmarked performance with reduced number of hall sensors in an equipment for pipeline inspection called caliper tool.Design/methodology/approach – The paper opts for an exploratory study by making various configurations of sensors possible under given constraints, analyzing results of each one of them and correcting the configuration.Findings – Instead of using highly sensitive hall sensors, one can increase the sensitivity of sensor by putting simple ferrite core as back yoke in order to detect weak magnetic field.Originality/value – This paper fulfils the need of detection of weak magnetic field by changing field direction and maximizing field component in direction of sensitive axis of magnetic sensor.