Haploidentical allogeneic hematopoietic cell transplantation (HHCT) using megadoses of CD34-selected hematopoietic stem cells (HSC) is complicated by slow engraftment and delayed immune reconstitution leading to intensive transfusional support, high risk of rejection and high incidence of life threatening infections. Graft CD3/CD19 depletion on a CliniMACS device results in grafts not only containing CD34+ stem cells but also CD34 negative progenitors, natural killer-, dendritic- and facilitating-cells, potentially leading to improved engraftment and immune reconstitution. We report a retrospective comparative study of eleven HHCTs with CD34 selected HSC (CD34) and seven HHCTs with CD3/CD19 depleted grafts (CD3/CD19) performed sequentially at a single institution with a median follow-up > 1 year. Conditioning was 12 Gy TBI, cyclosphosphamide (120 mg/kg) and ATG with or without either etoposide (40 mg/kg) or thiotepa (10mg/kg) in the CD34 group. All patients in the CD3/CD19 group received fludarabine (200 mg/m 2 ), thiotepa (10 mg/kg), melphalan (120 mg/m 2 ) and OKT-3 (5 mg/day, day −5 to +14). No postgrafting immunosuppression was used. Only the CD34 group received G-CSF posttransplant. Median age was 30 (range, 19–47) years in the CD34 group compared to 37 (range, 31–58) years in the CD3/CD19 group. Diagnoses in the CD34 group included acute myeloid leukaemia (AML, n=3), acute lymphoblastic leukaemia (ALL, n=3), chronic myeloid leukaemia (CML, n=2), and one patient each with Non-Hodgkin's lymphoma, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria. Diagnoses in the CD3/CD19 group were AML (n=3), ALL(n=3), and multiple myleoma (n=1). Graft composition was comparable with a median of 9,6x10E6 CD34+ cells/kg and 2,2x10E4 CD3+ cells/kg in the CD34 group versus 7,6x10E6 CD34+ cells/kg and 1,3 x10E4 CD3+ cells/kg in the CD3/CD19 group. The grafts in the CD3/CD19 group, however, contained significantly more CD34 negative cells (99 versus 3 %, p= 500 neutrophils/μL of 13 versus 19 days (p= 20000 platelets/μL of 13 versus 35 days (p=


ABSTRACT Despite curtailed budgets, academic libraries can create new or augmented instructional platforms and expand their institutional offerings with low-cost collections acquisitions obtained from commercial internet auction sites, flea markets, and retail sites. Using these low cost acquisitions, librarians can create numerous interactive, primary research exercises that result in enhanced special collections use and improved student engagement.


Defining counterurbanization as the redistribution of population down the functional urban hierarchy this paper demonstrates that this form of population deconcentration has occurred in Britain. According to the evidence assembled here this process was already underway in the 1960s and moreover was running at its highest rates during the early years of the 1970s. Since then there has been a remarkable recovery in the population change rates of the larger metropolitan centers particularly London but deconcentration remains the prevailing force and shows some signs of a further upturn according to the most recent evidence. There is ample evidence of both economic restructuring and of people expressing their residential preferences. Maybe the continued shift towards less urbanized localities alongside the recent recovery of Londons change rate signal both these factors in operation at the same time. Whatever the cause such simultaneous population trends are not unique to Britain nor new for it was several years ago that an observer of development in the US noticed the dual trends of back to the countryside and back to the city in the same decade. What is certain from the research on Britain and other countries is that population redistribution across the settlement hierarchy is not a simple phenomenon with a single direct cause but rather is the outcome of a tug-of-war between alliances of centripetal and centrifugal forces which change in their strength and their very nature over time.


There are number of sources for generation of power but in the recent years wind energy shown its potential as the clean source of energy and contributing to the high-energy demands of the world. Vertical axis wind turbine (VAWT) is the best option for the area, which are under load sheading. Thus, in this paper, VAWT blades for low average wind speed regions like Al Khobar in Saudi arabia is designed and implemented. Performance and power produced are investigated and utilized in the design and the economic analysis. An experimental and theoretical review on the performance of Savonius VAWT is presented. The turbine was made of Aluminium alloy with a blade angle of 160 degree and maximum coefficient of power, Cp, of 0.286. The results of this current study showed that the power output, with speed of minimum speed of 12-15 m/s generate 40-80 watts with an efficiency of 31~35%.


Arid and semi-arid areas are specially susceptible to soil degradation processes such as erosion and salinization and the influence of land use. The identification of soil degradation stages form an important basis for sustainable land use and land conservation. The key aim in this work is to combine multispectral with radar data and to evaluate their effectiveness for delineating soil degradation stages in semi-arid environments. Radar images have the advantage of being very sensitive to textural differences along land surfaces. Principal component analysis is performed on two data sets using the six reflective bands of Landsat ETM+ including the mean texture band of ERS-2 SAR and using only the six ETM+ bands. To evaluate the usefulness of the textural information for delineating the soil degradation stages an automated classification is performed on both PC data sets. The methodology for identifying soil degradation stages is performed on test sites located within an area in the Central region of Spain. Ground truth verification is carried out to confirm the results obtained. Different soil degradation stages, according to the soil surface characteristics, are successfully identified in the study area. The ERS/ETM+ based classification has significantly improved the separation of rugged landscape features along the slopes from those in the plateau area.


We present an inverse scattering approach to defects in classical integrable field theories. Integrability is proved systematically by constructing the generating function of the infinite set of modified integrals of motion. The contribution of the defect to all orders is explicitely identified in terms of a defect matrix. The underlying geometric picture is that those defects correspond to Backlund transformations localized at a given point. A classification of defect matrices as well as the corresponding defect conditions is performed. The method is applied to a collection of well-known integrable models and previous results are recovered (and extended) directly as special cases. Finally, a brief discussion of the classical r-matrix approach in this context shows the relation to inhomogeneous lattice models and the need to resort to lattice regularizations of integrable field theories with defects.


The burden of non‐communicable diseases in Africa is rising rapidly and implementation of evidence‐based control strategies is needed urgently. Testing people for hypertension and diabetes will be an important component in the fight against these diseases, as voluntary counselling and testing was for HIV‐infection. We discuss the below the areas where we believe evidence is needed to inform policy.


In the view of earthquake engineering, shear wave velocity (Vs) have been usually emphasized to understand the geotechnical phenomena and solve the geotechnical problems in seismic design and performance evaluation of structures. A variety of in-situ seismic tests were carried out for evaluating geotechnical dynamic characteristics at 183 sites in Korea and the Vs proftles with depth were determined as representative dynamic property in the investigated sites. Subsurface soil and rock layers of the target sites were reclassified into five geotechnical layers: fill, alluvial soil, weathered soil, weathered rock and bedrock, taking into account the simplified uses in geotechnical earthquake engineering practices. Representative Vs proftles for the five geotechnical layers were deduced by synthesizing the Vs profiles from seismic tests in field, and, based on the Vs profiles, a representative Vs value of each layer was deduced to provide for the earthquake engineer. Nevertheless, since the proposed Vs values of this study were derived using Vs proftle data under the limited site conditions in Korea, their continued improvements should made by additionally acquiring relevant data from a wider range of geotechnical characteristics.


The growth of mobile commerce will require development of both demand and supply sides of the market. On the supply side, the development of mobile applications (e.g. games, calendars, search engines) via cellular technologies will occur in a context partially defined by technical development dependencies that arise from the layered nature of mobile hardware and software technologies. This research finds that these technical application development dependencies shape both the strategies employed by entrepreneurs as well as the evolution of the mobile market. In particular, entrepreneurs are faced with technology choices and device uncertainties, while the market experiences fragmentation, intermediation and distribution integration. These results explain, in part, the slow development of mobile commerce in general, provide a basis for understanding future market developments, and are further evidence of the complex interdependency between technological and market evolution.


The reaction of cellulose with milk casein and epichlorohydrin was studied in order to prepare a viscose fiber grafted with milk casein. 15% of milk casein in an aqueous solution of 1% sodium hydroxide was reacted with 1_??_3% of epichlorohydrin to the weight of casein and then the product was added to viscose, which contained 15_??_20% of casein to the weight of cellulose.The spinning was carried out by the usual viscose spinning method and a new type of chemical fiber conbining cellulose with milk casein was prepared.This method of fiber-making is not that of merely spinning the mixture of cellulose and milk casein. Thus the properties of fiber obtained extensively varies in its properties depending on the amount of grafting agent (epichlorohydrin) used as well as on the relative amounts of the two polymers.In addition to the usual properties of viscose fiber, this fiber grafted with milk casein has such good properties as the the affinity to dyestuff for wool, fastness to light, burning resistance, heatretaining property and resistance against wool-attacking insects, moulds and mildews.


In this paper all steps of the theater information query system were realized by using the Hibernate framework technology,and method and skill used of Hibernate for data persistence are described.Combinated with JSP+Tomcat6.0 technology during the design.the method created application system based on Web has a very good reference.


With the constant deeply study and the rapid development of grid,the application of grid is expanded constantly.Grid technology that is suitable for different applications has appeared,and it has widely served production and various kinds of business activities directly.Through introducing the definition of grid and analyzing Globus Toolkit,some key technology of realizing grid application based on OGSA architecture and Globus platform is analyzed and probed into: Such as high-performance broadband net-work,grid system architecture design,grid operating system design,grid security authentication technology and grid application pattern design etc.


Microglia are the tissue-resident macrophages of the central nervous parenchyma. In mammals, microglia are thought to originate from yolk sac precursors and posteriorly maintained through the entire life of the organism. However, the contribution of microglial cells from other sources should also be considered. In addition to "true" or "bona-fide" microglia, which are of embryonic origin, the so-called "microglia-like cells" are hematopoietic cells of bone marrow origin that can engraft the mature brain mainly under pathological conditions. These cells implement great parts of the microglial immune phenotype, but they do not completely adopt the "true microglia" features. Because of their pronounced similarity, true microglia and microglia-like cells are usually considered together as one population. In this review, we discuss the origin and development of these two distinct cell types and their differences. We will also review the factors determining the appearance and presence of microglia-like cells, which can vary among species. This knowledge might contribute to the development of therapeutic strategies aiming at microglial cells for the treatment of diseases in which they are involved, for example neurodegenerative disorders like Alzheimer's and Parkinson's diseases.


William Torrey Harris (1835-1909) is best known as an American educator, editor, and philosopher. He served as a teacher in, and superintendent of, the St. Louis, Missouri, school system, and later as the U.S. Commissioner of Education. He edited Appleton's International Education Series, Webster's New International Dictionary, and the philosophy section of Johnson's Encyclopedia; he wrote numerous reports, papers and articles, and books. He was (with Emerson and Alcott) a founder of the influential School of Philosophy in Concord, Massachusetts, founder and editor of the Journal of Speculative Philosophy, and a promoter of Hegelian idealism. Yet, on several occasions, Harris took time from these activities to offer his critique of George's Progress and Poverty. (None of George's other works were discussed.) Harris believed that his basic arguments against George's ideas were never refuted. (1) Attack on the Deductive Method It is not surprising that Harris emerged as a critic of George since, on matters of economic theory, Harris was a disciple of Henry C. Carey. (2) Carey was a critic of the deductive method of analysis and the Ricardian rent theory in particular. Further, his theory of income distribution was quite different from the theories of the classicists and George. (3) Carey's ideas provided the foundation for Harris's critique. Harris's attack began in September 1886 in an address to the Saratoga meeting of the American Social Science Association. (4) The speech was important for several reasons. First, it set the pattern for all of his other attacks. Since Harris believed that his arguments were devastating and that they had not been refuted, he did little to revise them. Second, as Barker noted in his definitive biography of George, with this speech Harris became "the most famous person to speak against [George] in this period." (5) After some preliminary remarks, Harris, following Carey, attacked all of the classical economists, including George, for their use of the deductive method of reasoning. Carey claimed that the axioms of the classicists (wealth-maximizing behavior, drives to reproduce, etc.) simply did not adequately represent actual human behavior. He also claimed that when classicists applied deductive logic to these inadequate axioms they inevitably got inadequate results. Further, he charged that the classicists never detected the flaws because their test of their theories' validity was logical consistency, not the ability to explain and predict "real world" behavior. He maintained that if the classicists ever tested their theories against actual data, they would have had to reject most of their theories. (6) Harris, in similar fashion, said that classicists failed because they "set up principles for absolute ones which serve only for a nation of mere shopkeepers." (7) He too believed that empirical tests would lead to the rejection of most of classical political economy. Carey felt that one of the worst errors produced by the classicists was the Ricardian rent theory, a theory that postulated that the most fertile land would be settled first and that the margin of cultivation would then extend downward and outward as more land was needed. Carey said that the historical evidence of England, the home of most of the classicists, revealed that the reverse was true, namely, that the first settlements were in the hill country and that settlement extended to, not from, the richer soil of the river bottoms. (8) That pattern, insisted Carey, was quite general. Harris, in turn, argued that the Ricardian view was obviously incorrect because, if the best land had been settled first, the lush Amazon basin would have been settled before most other parts of the world. (9) In reiterating Carey's arguments, Harris apparently never realized that leading economists had refuted them twenty years before. John Stuart Mill reasoned that in areas of new settlement, in which labor and capital were scarce relative to land, people might not settle on land that would eventually prove to be the most fertile if initial cultivation of that land required more capital and labor than cultivation of another plot that would eventually prove less fertile. …


A highly effective and facile technique for catalytic ring-opening copolymerization (cROP) of lactones viz. e-caprolactone and e-decalactone with ω-pentadecalactone is being described. The reactions were mediated by Zn- and Ca-based tridentate Schiff base complexes and benzyl alcohol as initiator. The catalysts were successfully employed for the preparation of numerous block and random copolymers. To unravel the composition of the polyesters, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry was employed. Furthermore, the combination of solid-state NMR and XRD techniques revealed that not only the presence of branches but also intramolecular transesterification, resulting in low molecular weight cyclic structures, is responsible for a complex ordering of the polymer chain fragments. This paper focuses mainly on the detailed molecular characterization of the synthesized copolymers.


The running charm-quark mass in the MS scheme is determined from weighted finite energy QCD sum rules (FESR) involving the vector current correlator. Only the short distance expansion of this correlator is used, together with integration kernels (weights) involving positive powers of s, the squared energy. The optimal kernels are found to be a simple pinched kernel, and polynomials of the Legendre type. The former kernel reduces potential duality violations near the real axis in the complex s-plane, and the latter allows to extend the analysis to energy regions beyond the end point of the data. These kernels, together with the high energy expansion of the correlator, weigh the experimental and theoretical information differently from e.g. inverse moments FESR. Current, state of the art results for the vector correlator up to four-loop order in perturbative QCD are used in the FESR, together with the latest experimental data. The integration in the complex s-plane is performed using three different methods, fixed order perturbation theory (FOPT), contour improved perturbation theory (CIPT), and a fixed renormalization scale µ (FMUPT). The final result is ¯ mc(3GeV) = 1008 ± 26MeV, in a wide region of stability against changes in the integration radius s0 in the complex s-plane.


Zero reflectivity (unity transmissivity) surfaces on materials are useful for eliminating unwanted reflections. If the substrate is lossy and sufficiently thick, the incident radiation is totally absorbed. Using an impedance matching approach, the filling factor and groove depth of a rectangular-groove grating to produce zero reflectivity are calculated for lossless (dielectric) and lossy (metallic) substrates. These gratings are equivalent to a single homogeneous layer in the long-wavelength limit. The analysis is applicable to both TE and TM polarization and any angle of incidence. The antireflection behavior is verified for the gratings using the rigorous (without approximations) coupled-wave analysis of grating diffraction. Example zero-reflectivity gold gratings for an incident free space wavelength in the 0.44-12.0-μm range are presented.


Information-centric networking integrates by design a pull-based model which brings in advantages in terms of control as well as of in-network caching strategies. Currently, ICN main areas of action concern content distribution and IoT, both of which are environments that often require support for periodic and even-triggered data transmission. Such environments can benefit from push-based communication to achieve faster data forwarding. This paper provides an overview on the current push-based mechanisms that can be applied to information-centric paradigms, explaining the trade-off associated with the different approaches. Moreover, the paper provides design guidelines for integrating push communications in information-centric networking, having as example the application of this networking architecture in IoT environments.


Types of crystallizers. In the industrial application of single mass crystallization from solution clear aims exist with regard to crystallizate qualities. To fulfil these aims, one can choose between various types of crystallizers. Magma types, i.e. agitated tank crystallizer, forced circulation and draft tube (baffle) crystallizer, as well as classifying types with the well-known Oslo-crystallizer belong to the present state of the art. The rates of secondary nucleation decrease in the same sequence as that given above and the possibilities of influencing crystal size distributions increase, and coarser crystals are produceable.


The possible destruction in the soil of PAH present in sewage sludge-garbage composts in considerable amounts has been studied under various conditions. Sandy and loamy soil were mixed with the compost and kept in a climate chamber at 20 degrees C, 25 degrees C and 28 degrees C with 30% and 80% relative moisture. One part of the samples was illuminated the other kept in the dark. Control samples with and without compost were sterilized. PAH determinations, bacterial counts on Moutonagar and counts of the actinomycetes were carried out in regular intervals. No influence of temperature, moisture or light could be demonstrated under the experimental conditions. No difference in the behaviour of PAH concentrations in sterilized and nonsterilized soil samples during the periods of experiment, no increase or decrease of PAH were found. There was no correlation between bacterial counts and PAH concentrations. The laboratory experiments confirmed the results of the field investigations.


Abstract Purpose: Studies suggest that the concept of universal design (UD) is not widely accepted and that some of its ideas are received rather sceptically. This article confronts the concept of UD with prevailing notions and practices of design. It examines how UD can be situated relative to design in general, and explores whether elements in the nature of design can help us explain this scepticism. Methods: The article confronts writings about how design is understood with the concept and ideas of UD. This confrontation is substantiated with examples from studies of design processes in architectural design practice. Results: The confrontation highlights the ambiguity of how UD is framed and presented, ranging from an attitude over something utopian to a normative design domain. Conclusions: (1) Besides UD other attitudes are thinkable that address the diversity in human abilities and conditions. (2) The impossibility to really design for everyone may be inherent to design rather than characteristic of UD. (3) Even if UD as a normative design domain were a top priority, the question remains how to assess whether a design is universally usable given the nature of design (problems), and prevailing design practices. Implications for Rehabilitation Understanding disability as originating in the interaction between features of an individual's body and features of his/her environment, as universal design does, implies that rehabilitation specialists need to consider the context in which a person lives. Besides striving for independence, self-reliance and individualism, rehabilitation specialists may consider other attitudes to address the diversity in human abilities and conditions. Designers do not have direct access to the perspective of the people they design for. Assessing whether a design is universally accessible may benefit from expertise of rehabilitation specialists.


This article deals with the numerically controlled drafting process and cutting of steel plates by automatic flame burners for shipyard production. The computer processed production of control tapes for numerically controlled drawing machines and flame burners is now becoming highly valuable. The process of manufacturing the various parts of the hull, which may be bounded by the ship's side, e.g., double bottom floors, brackets, bulkheads, web frames, stringer plating, etc., can be fully automated and controlled by means of computer generated information. In this article the underlying principles of the methods used are briefly discussed and their overall economics reviewed.


Photographs of Eric Maffey and other military personnel in Egypt and Italy during World War Two. Includes postcards and photographs of street scenes in Alexandria, Sora, Napoli, Ischia and Salerno.
Quantity: 1 album(s) Album(s).
Physical Description: Purple plastic album 16.7 x 12.4 cm, containing 121 photographs


The paper presents a new method for the recognition of the different types of total and partial symmetry in boolean functions based on the numeric set-theoretical differentiation. The proposed algorithm is based on the theorem on the recognition of different types of partial symmetry. This algorithm, compared to the known, has a relatively less computational complexity of realization due to a comparatively smaller number of operations and procedures necessary for the accomplishment of the given task. This is proved by the presented examples for the recognition of the proposed method of the different types of symmetry in complete and incomplete of Boolean functions, including given in the SOP format, taken for comparison reasons from publications of the wellknown authors.


Spatial extrapolation of cropping systems models for regional crop growth and water use assessment and farm-level precision management has been limited by the vast model input requirements and the model sensitivity to parameter uncertainty. Remote sensing has been proposed as a viable source of spatial information for guiding model simulations, but techniques for merging remote sensing with cropping systems models have not been rigorously explored. We developed and tested two techniques for assimilation of remotely sensed green leaf area index (GLAI) into the CSM-CROPSIM-CERES-Wheat model: one based on model "updating" and the other based on model "forcing". A dataset from two wheat irrigation scheduling experiments, conducted at Maricopa, Arizona, during the winters of 2003-2004 and 2004-2005, provided canopy spectral reflectance information and measurements of canopy weight, wheat yield, and evapotranspiration (ET) under varying planting densities and nitrogen rates for testing the ability of the assimilation techniques to improve model simulations. Monte Carlo simulation methods were used to assess the performance of GLAI data assimilation in light of uncertainty in the model parameters that govern the GLAI simulation. When considering this uncertainty, assimilation of GLAI by "updating" and by "forcing" was able to reduce error between measured and simulated canopy weight and ET by 43.6% and 56.5% and by 45.0% and 51.6%, respectively, as compared to the stand-alone model. The assimilation techniques had greater difficulty improving wheat yield simulations because simulated yield was more sensitive to parameters other than GLAI, especially in the 2004-2005 growing season. Assimilation of remotely sensed data into cropping systems models has potential to improve simulations of key model outputs, such as canopy weight and ET, but further efforts are warranted to explore and fine-tune techniques for merging these two technologies.


Background:  Increase of antibiotic resistance is a worldwide problem. Within the 4 years before the turn of the millennium Helicobacter pylori strains isolated in children living in Vienna, Austria, showed a primary clarithromycin and metronidazole resistance of 20% and 16%, respectively. The aim of this retrospective follow‐up survey was to assess the further development and current antimicrobial resistance status.


Monolithic fuel plates have been developed utilizing low enriched U alloyed with 10 wt.% Mo to replace highly enriched fuels in research and test reactors, in accordance with the goals of the Materials Management and Minimization Reactor Conversion Program. The fuel plates consist of U10Mo fuel, Zr diffusion barrier, and AA6061 cladding. They are fabricated by co-rolling the U10Mo and Zr, which are then encapsulated via hot isostatic pressing of the entire U10Mo/Zr/AA6061 assembly. During fabrication, the metal constituents of the fuel plates undergo phase transformations as well as interdiffusion and reactions at interfaces. The areas of interest are the U10Mo fuel, U10Mo/Zr interface, U10Mo/AA6061 interface, Zr/AA6061 interface, and AA6061-AA6061 bond line. Knowledge of the transformations and growth in the plates is necessary to optimize fabrication parameters and predict behavior as they relate to irradiation performance. Numerous studies have been conducted to analyze these reactions in monolithic fuel plates, and a summary of their observations is provided in this paper.


Dr. John Smart III, Inline Services Inc., USA, talks about calculating velocity for solid particle movement in oil and gas pipelines.


We are now developing an accurate optical frequency measurement system at the telecommunication region using an optical frequency standard with Doppler-free acetylene absorption and a mode-locked fiber laser.


Autonomous robotic systems are approaching the maturity level to be able to support astronauts in space and on planetary surfaces. Commanding these robots with existing input devices and command modalities cannot cope with their increased capabilities and limits the usability for the astronaut. This paper presents alternative user interface (UI) concepts for the use with ubiquitous devices such as smartwatches and tablet computers. In particular, it is proposed to command an autonomous space robot assistant on a low to medium level of autonomy using a smartwatch. When commanding the robot on a high level of autonomy, a tablet computer can be utilized with object-centered task-level commands. The respective interaction concepts designed to make best use of the input devices are presented in detail. A comparison of the proposed interfaces and the presentation of the use of the tablet computer user interface in the METERON SUPVIS Justin ISS experiment concludes the paper.


between transport and land use policy objectives. A model of such interrelationships has been developed in order to provide a theoretical framework for integration of transport and land use policies. That model constitutes a system of integrated transport and land use policy objectives, which jointly aim at attainment of sustainable accessibility. The model has been used as a framework to compare two case study policies – transport and land use policies valid in Hannover (Germany) and Bristol (United Kingdom) regions. Within each case the degree of internal integration of the policies analysed has been assessed.


Determining travel demand within a region of interest takes a considerable calibration effort, requiring transportation surveys, traffic counts, and empirical trip volumes. However, there is a need for demand calculation without substantial calibration, for example to generate large-scale benchmark data for evaluating transportation algorithms. In this work, we present several approaches for demand calculation that take as input only publicly available data, such as population and POI densities. Our algorithms build upon the recently proposed radiation model, which is inspired by job search models in economics. We show that a straightforward implementation of the radiation model does not scale to continental road networks, taking months even on a modern 16-core server. Therefore, we introduce more scalable implementations, substantially decreasing the running time by five orders of magnitude from months to seconds. An extensive experimental evaluation shows that the output of our algorithms is in accordance with demand data used in production systems. Compared to simple approaches previously used in algorithmic publications to generate benchmark data, our algorithms output demand data of better quality, take less time, and have similar implementation complexity.


The clock skew and bandwidth limitations are serious problems for electrical interconnects when the clock rate in computer is pushed toward 1GHz and the beyond. Clock signal distribution using guided-wave optics provides a solution for these problems. The optical clock signals can be distributed to various locations using an H-tree polyimide waveguide structure with same delay time due to the equalized optical paths in the H-tree configuration. Surface-normal couplers are indispensable parts of such a system for the coupling of optical clock signals into and out from the waveguides while facilitating the packaging. A 45-degree surface-normal coupler was fabricated at the each fanout end of the H-tree structure. The waveguide is 10μm thick and 50 μm wide. The coupler is a 45 degree slanted end surface of the polyimide waveguide. The optical clock signals can be coupled out from the polyimide waveguides through the couplers surface-normally due to total internal reflection. The 45-degree surface-normal coupler can also couple the optical clock signal into the waveguide efficiently when the mode-matching condition is met. The coupler works for a wide range of wavelength. The measured output coupling efficiency is nearly 100%.


The ASTAP-compatible circuit optimization program (AOP) is employed to minimize the access time of a read-only store memory circuit. The design of this circuit provides an example particularly wellsuited to the application of circuit optimization techniques. The design involves finding the optimal values for three design variables. The design objective can be expressed with one simple optimize parameter.


Aims to examine the competitive characteristics of Scottish manufacturing industry as perceived by the companies themselves. Reports on an empirical survey of all medium (over 100 employees) to large manufacturing companies located in Scotland. The high response rate reflects the topicality of the subject‐matter at director level. Begins by providing a brief profile of respondents, then focuses on the present situation facing Scottish manufacturing companies. Themes discussed in this section include: marketing practices; current competitive features; buying/purchasing effectiveness; planning, control and appraisal methods and finally the critical factors which are currently providing a competitive edge to companies′ activities. The next section briefly discusses present and future issues relating to exporting and Europe. Finally looks to the future by examining issues such as internal factors of importance to business success, proposed investment in engineering/ manufacturing techniques, future challenges...


The most actual aspects of application in various areas of medicine of modern biomedical technology – platelet-rich plasma are reflected in article. In the last decade is celebrated significant increase in interest to this biotechnology that is caused by its high efficiency at high level of safety and low prime cost. Now platelet-rich plasma actively it is applied in surgery, stomatology, traumatology and orthopedics, sports medicine, cosmetology and dermatology, a combustiology. At the same time apparent defect of an assessment of application efficiency and the remote results autoplasm from the point of view of evidential medicine is still noted. Platelet-rich plasma possesses a number of useful properties: accelerates processes of regeneration of fabrics, anti-inflammatory effect, decrease in a pain syndrome that opens still big prospects for application in surgery, traumatology.


A clinical picture in the patients examined with occupational pathology after exposure to whole-body vibration with low frequency included: vegetative-sensoric polyneuropathy of the upper and lower extremities; peripheral angiodystonic syndrome with acroangiospasm attacks in the upper extremities; compressive neuropathies with a primary arm nerve lesion; cerebral angiodystonic syndrome, a definite contribution of which into its development, very likely, reflex effects from neck tissue receptors and the upper shoulder girdle make as well as function alterations in vestibular apparatus; myofascial painful syndrome having a specific distribution.


The main cause of the financial crisis (late 2008 - 2010 p.), Which is devastating the world is watching now, consider the rapid spread of financial globalization, moving the bulk of the world's financial (and investment) resources from the real (production) sector to the financial sector services and real estate markets.


Molist and Portell offer a "snapshot" of the state of reading, libraries, literature, and publishing in Spain, noting major trends, titles, publishers, and authors who are making a significant impact on the future of literature for young people in all the regions of Spain.


Objective: To determine the diagnostic delay in newly diagnosed tuberculosis (TB) patients admitted to a community hospital in Qatar. Design: The study was conducted from January 2013 today 2016. The following information was collected from patient file: Age, sex, nationality, tuberculosis type, time of symptoms onset, time of the confirmatory test, and the time of visiting an HCP before the admission encounter. Results: Of the 390 TB patients included in the study, 281 (72.1%) were from South East Asian countries, 325 (83.3%) patients were males and 65 (16.7%) were females, mean age was 32.4 years. Of the 390 patients, 89.7% (350 patients) had pulmonary tuberculosis and 40(10.3%) patients had non-pulmonary localization. The median total delay was 30 days (15;60 days), while the patient delay was 10 days (4;27 days) and the system delay was 3 days (3;7.8 days). For pulmonary tuberculosis, the total delay was 30 days and for non-pulmonary localization was 15 days. Conclusion: The study provides an insight about the delay in the diagnosis of TB at a community hospital in Qatar. Additional studies should be conducted to evaluate the delay in a representative national sample and to identify the factors associated with patients' delays, which could be used to strengthen the national program for tuberculosis control.


A theory of Fabry Perot resonator is developed on the basis of the cavity picture, in contrast to interferometer picture of the ordinary theory. The radiation leakage from the open surface is treated as a boundary value problem. This theory is applied to the circular Fabry Perot resonator and numerically calculated for the case of the laser resonator. A concise formula is derived for the diffraction loss, which also shows the explicit dependence on the mode of resonance: δd=2.40×10-2\varLambda2emN-3/2, where \varLambdaem denotes the m-th root of Jl, N≡a2/Lµ, a the radius of the disc, L the axial length and µ the wave length.


In recent years Gandia, a medium-sized town located on the Mediterranean coast of Spain, has become an outstanding example of local economic growth within the region, while at the same time facing important challenges. These include the arrival of immigrants, the need to adapt the local economic system and the labour market to an increasingly competitive and global economy. Since 1998 the municipal Centre for Integral Services and Municipal Employment (CSI-COM), has led a collaborative effort by local actors to face up to these challenges. CSI-COM is an example of good practice in the promotion of skills, employment and economic development at local level. It does so by enhancing non-mobile or nonmaterial resources for development, such as human resource training and the diffusion of information and knowledge, and by increasing the region's entrepreneurial capacity. This paper focuses on the elements of the CSI-COM strategy which relate to skills. Given the changing needs of local industry and the arrival of an important new pool of labour market supply, skills and vocational training are becoming increasingly important for town. The innovative CSI-COM structure has allowed all the relevant partners to come together to tackle skills issues using a common agenda and a common information base.


BACKGROUND
Dental litigation has a key role for the autonomy of the dental profession. We conducted a study among legal dental expert witnesses in order to reflect the present situation and reveal the potential for professional development.

METHODS
A questionnaire was distributed among 161 participants of the Karlsruhe training for legal dental experts between 2004 and 2009. They were asked to describe and to reflect on the present situation of dental litigation in Germany.

RESULTS
83 questionnaires were returned (51.6%). The main reason to become a legal dental expert was to "support the profession". 68 participants (85.0%) think that civil action resulting from dental treatment will become more frequent. The quality of dental expert opinions is considered to be in need of improvement. Strategies to optimise dental expert opinions and to deal with the potential growing number of claims are developed.

CONCLUSION
Basic and advanced training for dental expert witnesses assures the quality of dental expert opinions and also provides a chance for the further development of the dental profession.


The paper deals with mathematical modelling the low-frequency dynamic processes within liquid rocket engines (LRE). Attention in the work is devoted to developing the mathematical model of the cavitation oscillation for modelling the dynamic processes within the pump systems at the high cavitation number. To attain this objective, the experimental and calculated dependences of the cavities elasticity on the pump parameters at the high cavitation number are corrected including the cavitation number resulting in cavities within the centrifugal- impeller pump. The dependence of the cavities volume on the operating conditions of the pump is determined using the experimental and calculated method of the measurement of the elasticity and the cavities volume within the centrifugal-impeller pumps. The dynamic cavity equation is derived in the differential form. In the calculations of LRE starting, it allows to use the derived analytical dependences for a nonlinear hydrodynamic model and to take into account the fluid compliance (under cavitation-free conditions of the pump operation) within the supply line without changing the structure of the mathematical model of the LRE starting and discontinuous changing the values of the equation coefficients. The research results can be used to take into account the cavitation effects within the pumps for calculating LRE starting.


Background of the study: Worldwide it seems that the child who have not single or both parents they are widely suffer from various psychological conditions as they are very prone to get hurt due to lack of love and affection. Moreover, some research paper shows that orphan children have hopelessness because no one is available to help them. Researchers had established that orphaned children are more expected to suffer from internalizing troubles, such as depression and anxiety. Objectives: 1) To assess the level of depression among orphan children 2) To assess the effectiveness of spiritual prayer in reducing level of depression among orphan children. 3) To find out the association between level of depression with selected socio-demographic variable of orphan children. Methodology: A Quantitative quasi experimental study was done among orphan age people in selected orphan age homes of Central part of Gujarat State with depression. 70 orphan age children were chosen by convenient non probability sampling technique then samples were assigned through the randomization in to experimental group. Data were collected using child depression inventory. The spiritual prayer was continued for 14 days, for twice a day for 6 min. Result: Spiritual prayer reduced the depression level among orphan age children in selected orphan age homes. Experimental participants (n=35; M=6.60, SD= 1.94) depicts significant reduction in level of depression compared with control group (n=35; M= 0.31, SD= 0.58) (p = <0.0001, 95% CI [5.60-6.97]). Conclusion: Researcher felt spiritual prayer can be effective non pharmacological, non-invasive therapy to reduce the level of depression among orphan age children.


In Elaine May's professional biography, her role as actor tends to traditionally fall somewhere in line after the fields for which she is most immediately recognized – comic, screenwriter, director. Yet across a range of feature films in particular, May demonstrated a clearly highly developed skill for performing a range of different roles to camera. For a figure whose achievements are associated so readily with language, what becomes apparent when watching May act on film is how much she relies on the unspoken for lasting effect: gestures, facial expressions and movement inform her characterizations often just as much as dialogue and script. This chapter considers not only May's performance in perhaps her most well-known screen role as Henrietta in her directorial debut A New Leaf, but more also in her numerous collaborations with a range of acclaimed directors where her role was solely as actor.


It is established that adding glaukonit in fattening gilts rations results in both qualitative and quantitative body structure changes of the young animals under study. It is noted that the best results have been observed in gilts of the 2-nd and 3-d groups fed on rations supplemented with alyumosilikat glaukonit.


(Reported to House from the Committee on Agriculture with amendment, H. Rept. 94-618) Rice Production Act - =Title I: Rice Allotments and Price Support= - Directs the Secretary of Agriculture, under the Agricultural Adjustment Act of 1938, to establish for each of the 1976 and 1977 rice crops a national acreage allotment of 1,800,000 acres. States that the national acreage allotment shall be apportioned, for each crop of rice, by the Secretary to farms and producers on the basis of allotments established for the 1975 crop. Provides for reserving a portion of the rice allotment for apportionment to new rice farms and new rice producers. Sets forth criteria for reducing or withdrawing entirely the rice allotment of a farm or producer which plants to rice less than the total acreage allotted to it for that crop. Defines exceptions to such criteria. Authorizes the Secretary to transfer for any year because of natural disaster all or a part of such rice acreage for any farm in the county or in any other nearby county on which one or more producers on the farm from which the transfer is to be made will be engaged in the production of rice and will share in the proceeds in accordance with such regulations as the Secretary may prescribe. Directs the Secretary to permit the owner and operator of any farm for which a farm acreage allotment has been established to sell or lease all or any part to any other owner or operator of a farm in the same administrative area, or to transfer all or any part of such allotment to any other farm owned or controlled by him in the same administrative area. Provides for the apportionment among the heirs of a rice producer of the farm rice acreage allotment of such producer in States in which the allotment is based on past production of rice. Provides for apportionment of acreage upon dissolution of a partnership in such States. Provides for the voluntary surrender to the county committee of a portion of a farm's rice acreage allotment. States that


Engineering geological conditions in our country are complex and diverse. Many high-rise buildings, bridges, and launch towers are inevitably built on high and steep slopes. Heavy rain, earthquake, human engineering activities, and other factors lead to frequent landslides, soil creep deformation, and overall sliding, resulting in a certain bending moment and flexural deformation of foundation piles, may cause damage to the substructure and foundation pile failure, and then endanger the safety of the superstructure. In the past, bridge pile group foundation was used in bridge pile foundation engineering to improve the impact situation, but the stress environment of bridge pile foundation in landslide is obviously different from that of bridge pile foundation in the flat area. The large deformation of soil in front of the pile will easily cause the phenomenon of soil sliding and peeling, which will increase the technical difficulty of antislide pile construction. Based on this, this study firstly briefly introduces the relevant theories and technologies of railway landslide antislide pile technology and then establishes the static model of railway landslide antislide piles with different nanomaterials. Finally, the reinforcement technology of different nanomaterial antislide piles for railway landslide is expounded, which can provide guarantee for the application of different nanomaterial antislide piles for railway landslide. The results show that the preloading is carried out according to 1/10 of the design load to reduce the void between the soils. After the load is maintained for 2 hours, the load is unloaded to 0, and good skid resistance can be obtained.


The chart proposed by Sereda for the main classes of inorganic compounds was used to teaching chemistry in high school.The chart is a two-dimensional list of classes of compounds and takes advantage of visual memory and organizes compounds into classes.It could also be used in the teaching process of acidbase reactions.This chart can help students to memory the chemical compounds and the reaction process.It could also promote the effects of learning and increase the attractions when it was used in teaching.


This paper summarizes David Hendry's empirical econometric methodology, unifying discussions in many of his and his co-authors' papers. Then, we describe how Hendry'S suite of computer programs PC-GIVE helps users implement that methodology. Finally, we illustrate that methodology and the programs with three empirical examples: post-war narrow money demand in the United Kingdom, nominal income determination in the United Kingdom from Friedman and Schwartz (1982), and consumers' expenditure in Venezuela. These examples help clarify the methodology'S central concepts, which include cointegration, error-correction, general-to-simple modelling, dynamic specification, model evaluation and testing, parameter constancy, and exogeneity.


Traditional pushover analysis is performed subjecting the structure to monotonically increasing lateral forces with invariant distribution until a target displacement is reached; both the force distribution and target displacement are hence based on the assumption that the response is controlled by a fundamental mode, that remains unchanged throughout.


The advent of COVID-19 has allowed a rapid expansion of telemedicine (TM) and its implementation in various specialties. Despite this extensive use of TM, its role in rheumatology is conflicting and much remains unknown about TM's acceptability and efficiency in rheumatology [1].Our study aimed to evaluate rheumatologists' and patients' willingness for TM and factors helping to adopt this alternative.We conducted a cross-sectional study including patients attending our rheumatology department as well as rheumatologists. Patients were contacted by phone and rheumatologists were invited to answer a questionnaire via Google Form. We evaluated their points of view and suitability for TM by inquiring about their experience with tele-rheumatology, information technology supports, personal barriers to telemedicine, and reasons for adopting this alternative. Moreover, additional questions probed the clinician's perception of the appropriate clinical context for TM application as well as the corresponding legislation.Overall, 135 responses were collected including 60 rheumatologists and 75 patients. The distribution of diagnosis was as follows: rheumatoid arthritis (RA) (n=15), spondyloarthritis (SpA) (n=20), juvenile idiopathic arthritis (n=23), and osteoarthritis (n=17). Of the rheumatologists, 76.2 % were aged between 30 and 50 years old, 79.3% reported working at an academic center, and the majority were physician-level practitioners (71.2%), working for more than 5 years (61%). Afforded electronic devices were as follows: laptop (87.9%), smartphone (70.7%), afforded headset microphone (24.1%), camera (29.3%) for doctors. Forty-six percent of the rheumatologists estimate that they have a good internet connexion, 62.7% had an appropriate place for teleconsultation. Nearly, 40.7% of the rheumatologists were familiar with the concept of TM but only 39% reported experience with TM. Willingness to accept this model of care for rheumatologists and patients was found in 78% and 37.3% respectively. According to the doctors, the benefits of TM encompassed tele-training (61.7%), remote medical monitoring (61.7%) especially during the COVID-19 (70.2%), benefits for patients (74.5%), reduced inequalities in access to healthcare (46.8%), and improved quality of care (29.8%). The main barriers to TM were the lack of clear legislation (47.8%) and financial compensation (17.4%). Clinicians and patients identified common barriers to effective tele-rheumatology as the inability to perform a physical exam (91.3% vs 33.3%), the fear of trivializing the disease (34.8% vs 36%), and the lack of resources and infrastructures (43.5% vs 29.3%). The majority of the doctors (86.2%) expressed their willingness to attend training workshops. Reported areas to apply TM according to the doctors were mainly osteoarthritis (76.3%) and rheumatic diseases (64.4%), but also pediatric rheumatology (28.8%) and undiagnosed new patients (3.4%). Regarding legislation, most of practitioners estimated that it should be selective with specific authorizations (42.4%) or relaxed with the possibility of derogation (32.2%). Twenty-two percent of them reported that legislation should be strict with the possibility of sanctions, whereas a minority (3.4%) opted for a free practice without regulation at all. Factors associated with adherence to TM were age<40 years (p=0.036) for doctors and familiarity with the concept (p=0.006) and electronic devices afforded (p=0.000) for the patients.Findings from this study showed the reluctance of the patients to adhere to TM compared to doctors. Concerns and risks may lessen for both sides, once remote consultations are applied. Nevertheless, patient education is required for the success of TM application.[1]Sloan M, Lever E, Harwood R, et al. Telemedicine in rheumatology: A mixed methods study exploring acceptability, preferences and experiences among patients and clinicians [published online ahead of print, 2021 Oct 26]. Rheumatology (Oxford). 2021;keab796.None declared


APPLE Computer sponsor AwarlAwards Freedom of environme information will be a m political issue in parfiar in 1990. Tbe governmem promised tbat the forthc ing 'Green Bill' will ad! pollution secrecy thr tbe specific provisions I tioned so far bave I limited. However, pre, from Europe may forco government's band. The European Com sion is proposing a blooded freedom of vironmental informa directive. This would tbe public a general rigl access to information a all forms of pollut Government departm andpollution agencies c witbbold information 0 1 they could justify secre: terms of speci exemptions. The government isop ing tbis. Instead it is st ingthemerits of tbecoo tional Britisb appro wbicb involves put limited but clearly del information on pu registers. But the gOl ment may bave to go beyond itscurrent prop, if it is to bead off Euro: pressure . Ironically, to [ustif approacb, tbegovernme now bolding uptbeEnv ment and Safety Info tionAct1988 asevidem itscommitment to open Tbis was tbe succe: private member's bill troduced by Chris Smith and promoted by tbe ( paign forFreedom of I. mation. But wben the was introduced, thego' ment went out of its WI try and kill it off. It twice denied a set reading, and goverm amendments in comm later reversed att, ted to slop tbe public II ing about major bazards. The Act req key pollution and s, agencies to keep registe enforcement notices Sf on firms who break Sl limits. Tbe main disclosure vision promised unde r new 'Green Bill' will ret local autborities to se registers sbowing bow 0 airpollution isemitted b dividual factories . SOD tbe more complicated dustrial processes wi!


The article provides a brief analysis of the formation and development of physical education in higher educational establishments of Russia, the Soviet Union and the Russian Federation, the main feature of which was focus mainly on training students to perform military duties, conquest by students of the sporting awards and professional skills. The current realities of the market economy have placed greater demands on the formation of the healthy way of life and need for physical training of future specialists that can be formed only independently, following the moral certainty and choosing, in the process of training in their spare time, based on the convergence of personal and social interests.


This article presents the results of an experimental investigation of heat transfer augmentation by porous media in a natural gas-fired radiant tube burner. The results show that significant heat transfer augmentation is possible with the use of porous ceramic inserts in both premixed and nonpremixed gas-fired radiant tube burners. Furthermore, this work has shown that geometry variations in the porous insert configuration can appreciably alter both heat transfer rates and mixing and chemical reaction rates in these systems. In the case of nonpremixed flames, the effect of variation of insert geometry is more than simple heat transfer augmentation via gas enthalpy conversion to thermal radiation by the porous medium. There is also a significant alteration of the reactive gas mixing (and therefore chemical reaction and heat release) rates along the length of the tube. The basic mechanisms that control the mixing rate and heat release distribution in these systems are still unknown. Nevertheless, it appears...


Based on some cultural and biochemical tests in addition to VITEK compact 2 system, 64 bacterial isolates distributed on 25 species were isolated from these cases, interestingly, Kocuria kristinae constituted the highest isolation percentage (13 isolates; 20.3%), followed by Staphylococcus haemolytics and Escherichia coli (8 isolates; for each). To our best knowledge, it is the first time that this bacterial species implicated in UTI in Iraq.


In a multiple-input multiple-output (MIMO) precoding system based on finite-rate feedback, the receiver sends a precoding matrix to the transmitter via a feedback channel. The overall system performance is degraded due to feedback error. In this paper, we propose a robust feedback scheme that employs the index permutation technique to provide the system with redundancy-free protection against the feedback error. The wireless channel is assumed to experience Rayleigh fading, and the feedback channel is modeled as a discrete memoryless channel (DMC). Using the average chordal distance as a metric, the design of the index permutation in the feedback scheme is formulated into a minimization problem. An upper bound on the average chordal distance is derived, and the permutation design problem is simplified based on the bound. A modified binary switching algorithm is then developed to search for good permutations. Simulation results show that the proposed feedback scheme well compensates for the performance degradation caused by feedback error.


Barnet and Macfarlane 1 have recently reported on the use of snake venom for local hemostasis. Their best results were obtained with venom of the Russel viper. We have been working along similar lines with the venom of the Bothrops atrox (Fer-de-Lance). This reptile is a native of Central and South America and is fairly easy to obtain and keep in captivity. Thus, unlike the Russel viper venom, a plentiful and relatively cheap supply of this venom is readily available. Two different samples of the dried venom were obtained through the courtesy of Dr. R. P. Connor, of the United Fruit Co. The samples represented pooled venoms from "milkings" carried out at the Serpentarium, in Tela, Honduras, several years ago. In the experiments, the venom was diluted with physiologic saline. The minimum lethal dose for pigeons (intravenous route) weighing 250-350 gm. varied from 0.2-0.25 mg.; the minimum lethal dose in rabbits (intravenous route) of approximately 2 kilos, was 0.015-0.02 mg. These figures were determined on a large series of pigeons and rabbits with both samples. V. Brazil gives 0.01 as the m.l.d. for pigeons and 0.07 mg. as the m.l.d. for rabbits We have consistently found, as can be seen from our figures, that pigeons were much more resistant than rabbits to the toxins (neurotoxins) of the venom. The haemorrhagine content of the Bothrops atrox venom was titrated according to the method of Witebsky, Peck, and Neter. 2 One sample failed to elicit hemorrhage in a 1% solution, while the other sample produced a moderate amount of echymosis in 3 minutes when 1 cc. of the 1% solution was added to the chicken embryo. It was, however, decidedly poorer in hemorrhage-producing substance than Moccasin venom. The coagulating power of Bothrops atrox venom was tested on the blood of 2 hemophiliacs: L.E., age 25, whose clotting time was 58-60 minutes and V.B., age 36, whose clotting time varied from 1 hour and 40 minutes to 1 hour and 46 minutes.


The research on 3D hand reconstruction by images is a hot topic in computer graphics and computer vision, and it is positively related to virtual reality and augmented reality. There are many methods for 3d hand reconstruction, but most of the existing models only consider the hand pose and geometrical shape, not the delicacy of the surface of the hand. To close this gap, in this paper put forward to add hand texture modeling to the modeling of 3D hand reconstruction, especially the modeling of hand hair. The experiment results express that our method improves the 3d hand fidelity by increasing the modeling of hand hair texture.


A new method for the computation of complete Stark profiles for multielectron systems is presented. Modern electron scattering techniques are used for the electron broadening while the ions are described within the framework of the model microfield method. The method has been applied to the C IV optical spectrum and removes many discrepancies found in the analysis of PG 1159 stars


A novel approach which exploits the geometry of extra spacetime dimensions has been recently proposed as a means to resolving the hierarchy problem, i.e., the large energy gap that separates the electroweak scale and the scale where gravity becomes strong. I will describe two models of this type: one where the apparent hierarchy is generated by a large volume for the extra dimensions, and a second where the observed hierarchy is created by an exponential warp factor which arises from a non-factorizable geometry. Both scenarios have concrete and distinctive phenomenological tests at the TeV scale. I will describe the classes of low-energy and collider signatures for both models, summarize the present constraints from experiment, and examine the ability of future accelerators to probe their parameter space.


This paper presents a method for extending operating system functionality in a way that is secure, eecient, simple, requires no kernel source changes, and is compatible with existing application binaries. Our approach is to enable extensions of the system call interface by loading a device driver into the kernel that redirects system calls to extension code running either in the kernel or in a user-level process. As a proof of concept, we have implemented a prototype of our system, Secure Loadable Interposition Code (Slic), on Solaris 2.4. Measurements of our prototype implementation demonstrate that extensions can be added with little runtime overhead. We have also implemented several extensions using Slic, which illustrates the functionality provided and demonstrate good performance.


This study investigates whether perceptual learning (e.g. Norris, McQueen & Cutler 2003; Eisner & McQueen 2005; Kraljic & Samuel 2006, 2007; Kraljic, Samuel & Brennan 2008) has crosslinguistic effects in Hindi-English bilinguals. We hypothesized that perceptual learning in bilingual listeners generalizes across languages to similar phonemes in an untrained language. In particular, this study tested whether perceptual learning generalizes from the English velar stop contrast to stop contrasts at various places of articulation in Hindi (velar, retroflex, and dental stops). Hindi-English bilinguals listened to English words containing ambiguously voiced velar stops. In a subsequent categorization task, the bilinguals showed marginal perceptual learning effects for English velar stops but no effects for any of the tested Hindi stop contrasts. The results suggest that perceptual learning effects in stops are specific to the language of training in bilinguals whose languages differ in their phoneme inventories and/or the phonetic realization of the relevant phoneme contrasts.


* Associate Professor of Law, University of Colorado Law School; J.D., Columbia Law School; B.A., Oberlin College. An earlier version of this Article was presented at the 2006 Annual Meeting of the Law and Society Association. I thank Jennifer Collins, Kristin Collins, Nestor Davidson, Maxine Eichner, Martha Albertson Fineman, Martin Guggenheim, Melissa Hart, Jill Elaine Hasday, Sarah Krakoff, Scott Peppet, William Pizzi, Colene Robinson, Pierre Schlag, Elizabeth Scott, Phil Weiser, Marianne Wesson, Robin West, and Noah Zatz for their insights and encouragement. For their thoughtful comments and criticisms, I also thank the participants in a faculty colloquium at Notre Dame Law School and a faculty workshop at the University of Colorado Law School. Finally, I thank Sania Anwar, Gail Goodman, Renee Neswadi, Teresa Tate, and Kirsten Westerland for their excellent research assistance.


Some attitude,motivation,contents and frequency of handicapped fitness activities in Guangzhou city were investigated by questionnaire The results show the handicapped in Guangzhou have relatively high attitude for fitness activities But their fitness quality is not very good The main problems are that handicaps are without suited sport item,family's care,economic status,and suitable sports establishment It suggests that knowledge and methods for exercise should be further popularized,and some error concepts should be changed


Article history: Received 21 April 2020 Received in revised form 18 June 2020 Accepted 25 June 2020 Available online 30 June 2020 Pressurized metered dose inhalers (pMDIs) are often used for the treatment of asthma and chronic obstructive pulmonary disease. This device is easy to carry, highly effective and extremely safe, allowing reliable, consistent dosage delivery, metered dose inhalers are the inhalation devices that doctors and patients can readily select from around the world. This pMDI inhaler system has a problem which is the particle does not penetrate into the alveolar. ANSYS Fluent Version 19.2 was used to find the best angle of the actuator nozzle by parametric analysis. Standard K-epsilon was used as the turbulence model with enhanced wall treatment function. Discrete phase model (DPM) was applied to represent the particle flow. The result shows the best actuator nozzle angle is 120-degree which affects the maximum magnitude of particle velocity.


The authors describe a real-time task planning algorithm, PLANNER. The high planning speed achieved in PLANNER is due to three techniques adopted in the planner. First, priority numbers are assigned to each literal of the conjunctive goals and each literal of the preconditions of the robot operations; the priority assignment is combined with a depth first search technique to make the goal-interaction problem vanish in task planning. Second, binary numbers are used to represent facts and robot operations, which greatly increases the speed of operation searching. Third, simple hardware circuits are used to match a subgoal to all operations and facts in a parallel fashion. The total speed gain of PLANNER over the traditional task planner is the product of the speed gains of these three techniques. PLANNER can be used for a fairly large subset of conjunctive problems that have priority among its subproblems.<<ETX>>


High-resolution ultraviolet spectrograms of the B-shell star Zeta Tau reveal two features characteristic of B supergiants, one at 1720 A and the other at 1920 A. The presence of these features in the spectrum of this object shows that they are indicative of an extended atmosphere - either the tenuous atmosphere of a supergiant or the envelope surrounding a rapidly rotating main-sequence star - and are therefore not purely luminosity criteria. The high spectral resolution allows an identification of the contributors to these features. The dominant contributor to the 1920-A feature is Fe III, while the primary contributor to the 1720-A feature is Al II.


India is the second largest producer of vegetables in the world (surpassed only by China) accounting for about 10 per cent of the world production. Okra, Abelmoschus esculentus (L.) Moench commonly known as bhindi or lady's finger (family: Malvaceae) is a popular fruit vegetable crop. In the plains of northern India, it is grown in summer as well as during the rainy season; whereas, in central and south India, the crop can be grown throughout the year. It is cultivated in 528.4 thousand hectares with a total production of 6146.0 thousand metric tonnes with productivity of 11.6 tonnes per hectare in India (Anonymous, 2016-17).


Abstract : In order to specify the role of dicarboxylic acids in lithium lubricants on the base of SZhK, the latter were isolated from the given commercial fraction by an extraction by 50 percent water ethanol. On lithium soaps of purified SZhK and dicarboxylic acids lubricants were prepared. On soaps of dicarboxylic acids isolated from the fraction of SZhK, it was not possible to obtain lubricants. The removal of dicarboxylic acids does not affect the properties of the lubricants. Apparently, this is explained by the insignificant content of dicarboxylic acids in the initial fraction of the SZhK. Also investigated was the lubricants prepared on lithium soaps of SZhK. As a result of the purification of SZhK, an increase in the thickening effect of lithium soap was noted to be similar to that of the purification by the carbamide method.


The invention discloses an electronic switch operation anti-jumping circuit. The circuit comprises a control power supply, a switching-on intermediate relay, a switching-off intermediate relay, an auxiliary intermediate relay, switching-on coils, switching-off coils, a switching-on button, and a switching-off button. The switching-off control loop consisting of the switching-off button, the coils of the switching-off intermediate relay and the switching-off coils, and a switching-on control loop consisting of the switching-on button, a set of normally closed contacts of the auxiliary intermediate relay, the coils of the switching-on intermediate relay and the switching-on coils are successively connected in series between the positive and negative electrodes of the control power supply; another electric node of the switching-on button is HA, a set of normally open contacts of the switching-off intermediate relay and the coils of the auxiliary intermediate relay are successively connected in series between the HA and the negative electrode of the control power supply, and the two ends of the normally open contacts of the switching-off intermediate relay are in parallel connection with the normally open contacts of the auxiliary intermediate relay; and two ends of the coils of the switching-on intermediate relay and the switching-off intermediate relay are respectively in parallel connection with clamp diode groups.


In recent times the increasing economic importance of electricity raised new interest in the study of its market. In particular the existence of an efficient derivative market where players can mitigate their risk exposure has been considered fundamental. In this work an analysis on the weak form of efficiency for the forwards market at Nord Pool is carried through taking the three most traded contracts as indicators. Different statistical tests and a scenario analysis on extreme conditions on the supply side are employed in order to gain a greater understanding of the state of the market. Evidences of inefficiency are found for the monthly and quarterly contracts, while the market shows higher levels of efficiency in a situation with abundant hydro power resources.


The development and application of automation system for oil storage tankfarm in Sinopec Zhenhai Refinery and Chemical Company are described.This automation system of oil storage tankfarm is consisted of data acquisition system of storage tank,monitoring system of storage tank and movement/management system of crude oil.The system application displays that the automation in operation and management of tank is realized,which increases the work efficiency and liberates the operators from heavy work.


Thinking steps of computational thinking skills have an essential role in forming creative thinking to find ideas in a structured manner. Not only developing creative thinking, but this stage also helps understand how to implement ideas into computational procedures. This study aims to design worksheets for helping the students understand and improve Computational Thinking Skill (CTS) in the material interpolation with the problem based learning (PBL) strategy. The development of worksheets using step: define, design, development, and disseminate. The development stage includes the evaluation from learning expert. In many studies, the application of PBL shows an increase in various student abilities. This research applied to 39 students of computational physics courses. The result shows there was an increase in CTS, such as abstraction from the complex problem, algorithm automation, data analysis, collection, and representation.


All cutaneous and mucosal surfaces can fall prey to fungi such as dermatophytes and yeasts. Here's how to recognize superficial fungal infections and initiate treatment.


The generation of virtual dynamic learning environments by mental imagery improved physical education of student teachers. Up-to-date studies showed that training computerized simulations improved spatial abilities, especially visualization of the body's movements in space, and enhanced academic achievements. The main program of the research concentrated on creating teaching units focusing on a variety of physical skills through computerized dynamic presentations. The findings showed that as the student teachers practiced the creation of simulations through the PowerPoint Software, it became clear to them how the computer is related to physical activities. Consequently their presentations became highly animated, and applied to the natural environment. The student teachers applied their presentations in their practical classroom and reported about their pupils' progress in physical skills. Moreover the motivation of the student teachers and pupils to both modes of learning, manipulating virtually and physically, was enhanced.


Sandia National Laboratories has found that the reliability and failure modes of current-generation network technologies can be effectively modeled using fault treebased probabilistic logic modeling (PLM} techniques. We have developed fault tree models that include various hierarchical networking technologies and classes of components interconnected in a wide variety of typical and atypical configurations. In this paper we discuss the types of results that can be obtainedfrom PLMs and why these results are of great practical value to network designers and analysts. After providing some mathematical background, we describe the "plug-and-play '' fault tree analysis methodology that we have developed for modeling connectivity and the provision of network services in several current-generation network architectures. Finally, we demonstrate the flexibility of the method by modeling the reliability of a hybrid example network that contains several interconnected ethernet, FDDI, and token ring segments. For many years, probabilistic logic modeling (PLM) techniques have been used to help assess the reliability of complex electromechanical systems ranging from individual components within automobiles to large precision machine tools and even complex semiconductor fabrication facilities. Related techniques have been used to assess the risks associated with potentially high-consequence facilities such as chemical processing plants and nuclear power reactors. These techniques provide designers and analysts with key insights that can be used to predict the most important failure modes and vulnerabilities in the system. They can also provide quantitative guidance as to the most costeffective ways to improve overall reliability. While PLMs have been commonly used in many industries, their use in the telecommunications industry has been fairly limited. The complex topologies of communications networks and the time-dependent interactions between components [ 11 have been difficult to model with the fault tree, event tree, and reliability block diagram models that have been used successfully in other industries. However, network designers and analysts could benefit greatly from the information that PLMs can yield. An interdisciplinary team at Sandia National Laboratories has found that, in general, current-generation network technologies can be modeled using PLM techniques. We have developed a "plug-and-play" fault tree analysis methodology for modeling connectivity and the provision of network services in a wide variety of currentgeneration network architectures (e.g., ethernet, token ring, and FDDI) containing various types of components (e.g., routers, concentrators, MAUs, CAUs, servers, and workstations) interconnected in a wide variety of typical and atypical configurations. This paper describes that modeling technique and illustrates why the results that can be obtained from PLMs are of great practical value to network designers and analysts. 2. Benefits of Probabilistic Logic Models PLMs have been used by a number of different disciplines, including quantitative reliability analysis (QRA), probabilistic risk analysis (PRA), and probabilistic safety analysis (PSA). Regardless of the discipline, the reasons for developing a PLM are the same: to identify an exhaustive list of the modes by which a system can fail, to find an approximate frequency with which we might expect to observe failures, and to determine a rank ordering of the components in the system by their "importance" to the proper function of the system. The "importance" of a component can be defined in a number of ways, but is often thought of as answering one of the following questions: How sensitive is the overall system reliability to changes in the reliability of each individual component? * If the reliability of this component is allowed to decrease (say, by substituting components of lesser quality), how much will this affect overall system reliability? 404 U.S. Government Work Not Protected by U.S. Copyright If money is invested to increase the reliability of this component, how much will this affect overall system reliability? Clearly the answers to these questions cut to the heart of how networks are designed and managed. For example, a PLM analysis might show that a particular concentrator does not contribute significantly to the unreliability of the system, but that it would become a significant contributor if its reliability were allowed to deteriorate. The analysis might also show that, while a particular router seems to be a major contributor to system unreliability, the funds required to replace it might be more effectively spent pursuing several less expensive upgrades. It might also show the opposite. PLM results should not be used as the exclusive basis for design and upgrade decisions because such decisions have intangible aspects that must also be considered. However, PLM results do provide quantitative answers to network reliability questions, and these quantitative answers can be used as a legitimate benchmark to get past the "gut feeling" that unfortunately forms the basis for many network design and upgrade decisions. It has also been demonstrated that PLM results are well suited for use in discrete optimization algorithms such as genetic optimization. The wealth of decision support information provided by PLM models sometimes tempts the uninitiated to view PLM as a "silver bullet" that makes traditional forms of network analysis such as dynamic simulation obsolete. This is most certainly not the case. PLM and dynamic simulation are complementary tools which, when used together, provide a more complete view of network performance than either can provide by itself. For example, dynamic simulations are often very computationally expensive, so it will not be possible to simulate each network variation that might be of interest, Insights from PLMs can help direct the simulation analyst to the most important variations so that they can get the most valuable information for the computational effort expended. On the other hand, direct simulation analyses will help PLM analysts to be sure that they have properly established important success criteria within their model. PLM provides a global view of the network and quantitatively leads a designer to options for its betterment, while direct simulation provides detailed information about critical situations within a particular network configuration. Clearly both perspectives are necessary for a complete understanding of the network. At this point someone usually asks, "You speak of quantitative results, but I have no data. Surely the value of your results cannot be any better than the quality of your data, so how can this be of any benefit to me?' That statement is true i f you are seeking to predict the absolute reliability of the system (e.g., mean time between failures). However, the most useful result from a PLM is often the rank ordering of components by importance. An accurate rank ordering can be achieved even with relatively little measured reliability data. An analyst can often state with relatively high confidence that component A is "somewhat more likely to fail" than component B, or that a router with internal redundancy woulid be expected to be "much more reliable" than a workstation. The analyst can create groups of components and failure modes such that all elements in the group have similar failure rates, and then rank these groups to obtain a reasonably accurate set of relative reliability data. The rank.-ordered results from a PLM are accurate even with only relative data. Thus, it is possible to obtain some of the most useful results from a PLM even in the absence of a great deal of measured reliability data. 3. Fault Tree Analysis Methodology The PLM method chosen for analyzing communications networks is fault tree analysis (FTA).[2] This section provides a brief background on the mathematics of FTA, followed by a description of how fault trees for both network devices and network architectures were developed and solved. This information lays the groundwork for the discussion of the "plug-and-play" fault tree analysis methodology that will be presented in later sections. 3.1 Mathematical Background FTA is a deductive method that seeks to determine how individual component failyres combine to cause the overall failure of a system. An FTA begins with the selection of a "top event" which is simply the definition of the system failure that is being exsmined. The FTA continues by finding the immediate, necessary and sufficient conditions (events) for the top event to occur. Next, the immediate, necessary and sufficient conditions that lead to each of these new events are found. This process is applied recursively until each event that remains cannot be further broken down. Events that cannot be further broken down are called primary events, and the fault tree development process is complete when there remin no "leaf nodes" of the fault tree that are not primary events. To illustrate the above process, consider a well that pumps water to a faucet. The top event, which is our definition of system failure, might be "no water comes out of the faucet." The immediate failures that can cause this event are "the faucet is broken" and "no water is available to the faucet." The immediate failures that can cause water to be unavailable at the faucet are "no water from the pump," which can be caused by "broken pump," "no power to the pump," or "no watler available from the well." The progression can be continued by investigating why water is not available from the well, or why power is unavailable to the pump, or why the pumlp or valve is broken. The decision of how far to go before declaring that something is a "primary event" depends upon the objective of the analysis. One can imagine that the fault tree model constructed by a pump manufacturer might look very different from that of a power s


useful. In xxvii. 8. 17, a late annalistic passage, the difficult Romani is as likely to be false history as a slip for Graeci, On 9. 7 add Salmon, J.R.S. xxvi (1936), 55 f. The references to De Sanctis, Storia dei Romani, vol. iii, pt. 2, might include the following important notes. On xxvi. 12. 2 and the case for per Samnium, not per Samnium Apuliamque, see p. 342; on Ausetanis at 17. 4 see p. 451, note 15; on Larinatis at xxvii. 40. 10 see pp. 457 ff.; on ad Senam at 46. 4 see p. 563. The translation, however, is poor. Phrases are rendered in detail, but not always accurately and too often without relation to the context. Examples occur on every page: it will be enough to cite one or two. xxvi. 1. 10 describes how the defeated army of Cn. Fulvius was degraded to the status of the legiones Cannenses: in this context foede with caesus fugatusque is not ' terribly' but 'dishonourably', huic generi militum is not 'soldiers of this sort' but 'this class of soldier', and additum . . . ignominiae is not 'added to the disgrace ' but ' an additional mark of dis-


In this paper, we focus on improving the performance of the piezoelectric diaphragms of valveless micropumps. A circular lightweight piezoelectric composite actuator (LIPCA) with a high level of displacement and output force has been developed for piezoelectrically actuated micropumps. We used numerical and experimental methods to analyze the characteristics of the actuator to select optimal design. With the developed circular LIPCA, we fabricated a valveless micropump by photo-lithography and PDMS molding techniques. The displacement of the diaphragm, the flow rate and the back pressure of the micropump were evaluated and discussed. With a semi-empirical method, the flow rate with respect to driving frequency was predicted and compared with experimental one. The test results confirm that the circular LIPCA is a promising candidate for micropump application and can be used as a substitute for a conventional piezoelectric actuator diaphragm.


Discloses an abrasion resistant particles having an average particle size not exceeding 2μm and comprises 100 parts by weight of alumina and / or silica and 5 to 25 parts by weight of cerium in the form of cerium oxide. Also discloses a process for producing the abrasive particles, and methods of using the flattening insulating film on a semiconductor.


The objective of the present study is to promote the education of holism in gerontology for the study of the ageing human being. We base our studies in the knowledge resulting from the exploration of our surrounding to detect psychological and social conditions of 20 old people. Who, with diverse pathologies and multifactor situations where attended in 3 years of investigation during which we noticed that their conditions improved. Taking us consider the human being as an "holo", a total, a complete reality and a consolidate of manifestations, values and expressions that reveals the integrity of their conditions. The makings of this condition are complete, unique, universal and undividable. They are expressions of multiples events, intervelated situations of a reality viewed and attended in it's complexity from each one of the aspects that make the patients identity. For the study of geriatrics and gerontology the number one condition resides in the holistic vision of the patient. With this perspective, we base our proposal in eight basic principals, which are: holos, universality, integration, identity, continuity, relativity, and a syntactic approach. In the holistic studies, is necessary the formation of specialized geriatric and gerontologists opened to a comprehension of a multidisciplined leadership. Conclusion. The improvement in the quality of the Latin American education concerning geriatrics results in an urgent assignment. This is important since the education serves as an instrument of promoting a transformation for a society in witch everyday the number of old people increases making it undeniable to attend their necessities. The theory of holistics in gerontology abides in the importance of a total view concerning the patient and his or hers standard of living.


The expressive and form-generating functions of the sonoristic timbre-texture are disclosed in a set of aspects among which an important position is taken by the semiotic function of the spatial organization of the musical text. The auditory space in Avet Terteryan's Sixth Symphony manifests itself in the guise of an important thematic and compositional component. The spatial characteristics of the musical texture contain "codas" in it, which carry out the symbolic connection between the music and its recipients. The semiotic field of Terteryan's symphony reflects a dialogue of cultures, generated by the composer's aesthetic, religious and philosophical position. In the system of the composer's musical language the organization of the auditory space demonstrates itself in the role of the lexis (thematic units) and grammar (the principle of the organization of the musical chronotope). The function of the lexical units is carried out by 1) timbres-symbols perceived as "voices in time" and 2) the artificially created image of the sounding space, which actualizes the image-related thematic arches towards church acoustics, natural landscapes and the metaphysical dialogue of the "visible world" and the "invisible world." the auditory space of the Sixth Symphony reveals a number of the basic modes of the artist's creative consciousness and the culture that generated it. The correlation of elements of the lexis of various types on the phonic, timbral-structural and semantic levels forms a unique type of compositional logic. The acoustical musical chronotope of the symphony reflects the Eastern Christian picture of the world, one of the most profound characteristics of which is the logocentric foundation, which is disclosed in the symphony's architectonics. The image of the Word forms the basis of thematicism and conception of the musical form. The organization of the auditory space discloses the iconic nature of the musical text. As the result of the composer's numerous utterances, helping us adjust for the perception of the composition, the possibility of transferring to a supra-musical sphere of creative consciousness arises. On this level the symphonic genre functions as an instrument of religious-philosophical cognition. Keywords: Avet Terteryan, the symphonic genre, sonoristic timbre-texture, the semiotic function of the auditory space.


A reversed-phase HPLC method for the determination of dechlorvos and malathion in the meantime was described.It had been used to determine the dichlorvos and malathion in emulsion concentrate with some advantages,such as the good reproducibility,no interfere of other components in sample and rapid determination.


This paper is about gender classification using face image and voice of a speaker. The basic aim of the paper is to predict the gender of speaker through voice sample using Auto-correlation method and predict the gender of speaker through their face image using fisher face algorithm and integrated the obtained to increase the accuracy of gender classifier. The algorithm has been applied with the help of MATLAB programming. A collected database of voice samples and image samples of male and female students has been concerned. The classification algorithm is applied on the database and accuracy of gender classifier is determined.


It has been hypothesized that autoimmune disorders may be induced by IFN therapy. The aim of this study was to evaluate whether thyroid-specific autoimmune disorders may complicate the treatment with IFN-β


Capturing the motion of a person and retargeting it to a virtual character with a different body shape is common practice in computer animation. This inconsistency between motion and shape often makes animations look unrealistic. It remains unclear which aspects of an animation affect how realistic it is perceived. Previous research has found detection of the inconsistency between motion and shape in biometric virtual characters to be at chance level for actions that involve object manipulation. Here, we test whether similar results are obtained for actions not involving objects and compare the detection of inconsistency in realistic female and male animation for actions with and without object manipulation. For creating our stimuli, we used the animations of five pairs of female and male performers with large differences in body weight from the bmlRUB database when throwing a ball, lifting a box, jumping, and walking. For each actor pair, we created inconsistent animations by combining the body shape from one actor with the motion from the other actor. For the consistent stimuli, the body shape and motion came from the same actor. In each trial of the experiment, participants observed one consistent and one inconsistent animation and selected which of the two they perceived to be inconsistent. Our results showed that for both female and male animations, participants' detection rate was above chance for walking, and was at chance level for throwing. For lifting and jumping, the detection rate was at chance level for female animations and above chance level for male animations. Overall, detection rate was low which is promising news for realistic human animations but tended to be higher for male animations. Future research should investigate a broader range of actions to determine which are perceptually most affected by motion retargeting.


upon as spokesmen for the West and the East are many. They relate to matters which vary from major immediate issues such as the peace treaties to relatively long-term matters such as codifying international law and drafting a world bill of rights. There are those who feel that irreconcilable political ideas and institutions have appeared in the world, and that such a situation spells eventual war. If these prophets are right, it becomes necessary for Americans as citizens of one of the principal parties to investigate the situation. They must judge for themselves what the issues


In this research work, the devastation caused by forest fires has been studied and a monitoring and alert system has been created to minimize the losses caused by such fires. There are numerous factors that either positively or negatively affect the generation and continuous spread of forest fires, which include multiple meteorological factors and elements from the Forest Fire Index. To understand the relationship between those attributes, historical forest fire data of Montesinho Natural Park was analyzed. Based on the most significant factor observed from the performed analysis, a wireless sensor network integrated with FPGA (Field Programmable Gate Array – used to prototype hardware designs) was created employing the sensor for the measurement and recording of the said factor. Furthermore, a topology apt for the deployment of the created early fire alert system has been suggested along with estimated sensor nodes required for particular area coverage based on the proposed topology.


A highly experienced level of quality testing capabilities for HVDC converters is one of the key pre-requisites in guaranteeing operational reliability and availability of HVDC transmission schemes. In this paper we combine both aspects by introducing the testing capabilities of a newly installed Power Converter Test Center together with an overview of reliability and availability of HVDC projects in operation.