Nilgiri tahr (Hemitragus hylocrius) were observed in the wild in Eravikulam National Park, Kerala, India. Agonistic and sexual behaviors were described and classified by social function.

The social behavior of Nilgiri tahr was compared with that of related species. Nilgiri tahr are thought to be evolutionary intermediates between the Rupicaprini and the Caprini; this was reflected in their behavior. While they used reverse parallel fighting and neckfighting, clashing with the horns was also well developed.


Doubly fed hydrogenerator system is a synthetical complex system which is made up of water,hydroturbine,generator and controllers.Due to the features of hydrogeneration system with multivariable nonlinear and strong coupling as well as uncertain parameters,a cascade-connected self-adaptive fuzzy neural network decoupling control strategy is proposed in this paper.The former is a self-tuning fuzzy controller by using the intelligent weight function rulers,the latter is a self-adaptive neural network decoupling controller based on the learning algorithm of dynamical coupling characteristic.In addition,the convergence of the network weight learning algorithm is derived by Lyapunov stability theory.The effectiveness and correctness of the presented control strategy is demonstrated under the uncertainty of water,turbine and generator parameters,the robustness performances of hydrogeneration system are simulated by Matlab/Simulink.Comparing with the conventional PID control,the results have shown that the proposed control strategy is of good robustness,decoupling ability against the variation of model structure and parameters.


The temperature rise inside the footwear is due to the three main factors of foot temperature, repetitive friction between the foot and footwear and environmental temperature (Shariatmadari et al. ...


In recent years, the Internet has greatly reduced the cost of minority shareholders to obtain information, and has also enabled them to participate in corporate governance more conveniently and effectively. Based on the data of China's A-share listed companies from 2011 to 2020, this paper examines the impact of minority shareholders' participation in corporate governance on corporate green behavior. The study found that the minority shareholders can effectively promote green innovation in enterprises. This conclusion still holds true after robustness tests such as replacement variables, multiple fixed effects, addition of omitted variables, and propensity score matching test. Further research finds that state-owned enterprises and non-heavy polluting industries, the participation of minority shareholders in corporate governance will have a more significant role in promoting green innovation. This paper not only enriches the research on minority shareholders of listed companies and green behavior, but also has important theoretical and practical significance for minority investors to protect their own rights and interests.


—The multicast services are effective solution for content delivery to groups of subscribers. Typical multicast applications include distribution of music, video, news, advertisements, weather information, software and other data. The multicast minimizes the network traffic in comparison to unicast as the content is accessible for all users subscribed for the service simultaneously. The efforts on further evolved Multimedia Broadcast Multicast Service (MBMS) in fifth generation (5G) mobile networks enable more optimal usage of network capacity and better quality of experience for end users. The MBMS requires deployment of additional functions in the core network, which from technical point of view introduces latency. There are use case scenarios where the latency has to be minimized, e.g. for mission critical applications. In this paper, we present an approach to provide MBMS functionality at the network edge using Multi-access Edge Computing (MEC) technology. MEC reduces latency as it distributes the cloud capabilities closer to the place where they are needed. The vicinity to end users enables more efficient usage of network resources and higher data rates in addition to latency reduction. Among the others, the deployment of MBMS at the network edge enables location based content delivery, e.g. broadband multicasting of sport events at stadiums. A new MEC service is proposed, which enables third party applications to manage multicast sessions. Using the service, a MEC application may create a new multicast session, delete an existing multicast session, get information about the multicast session, and manage user participation in a multicast session. A MEC application may subscribe to receive notifications about multicast session events and may be notified when such events occur. The proposed MEC service follows the Representational State Format (REST) architectural style. We present the service data model which describes the data type and the structure of resource, as well as methods supported by the resources. To illustrate the approach feasibility, we model the multicast session state as seen by the network and by MEC application, and prove formally that both models are synchronized, i.e. they expose equivalent behavior. We also discuss service performance in terms of introduced latency. The latency "injected" by the service is evaluated theoretically through signaling for multicast session management. Based on published empirical data for MEC performance we determine the distributions which fit best to these data applied to the proposed MEC service. Manuscript received August 16, 2019; revised March 6, 2020. This work was supported by the Bulgarian National Science Fund, Ministry of Education and Science under Grant No. DH07/10-2016. Corresponding author email: email@example.com. doi:10.12720/jcm.15.4.309-317


Introduction The human peripheral auditory system is divided into the outer, middle and inner ear. The acoustic signal innervates the eardrum. The ossicles carry the signal forward to the inner ear. The system of the three ossicles transforms the acoustic signal. Another function of the middle ear is to protect the inner ear against loud noise. In the inner ear, the structure being responsible for hearing is the cochlea. It incorporates the organ of Corti containing the sensory cells that perform the transduction from mechanical excitation into auditory nerve signals. The cochlear can be described physically by three sections filled with fluid and separated by membranes. One of these is the basilar membrane. Acoustic stimulation by external sound is transformed into traveling waves with amplitude peaks at different places on the basilar membrane depending on the frequency of stimulation. An active mechanism including the outer hair cell somatic electro motility can add energy to the basilar membrane by providing positive feedback to the membrane vibrations. This phenomenon of cochlear amplification results in high sensitivity and increased frequency selectivity of the ear.


For Chinese ironmaking process, reducing the consumption of blast furnace fuel was the key to relieve the greenhouse gas emission and lower ironmaking cost.1) What's more, with the current increasingly shortage of high quality coking coal, how to reduce the dependence on high quality coking coal was an extremely problem which should to solve for Chinese steel industry.2–5) Many researches had investigated the feasible of using carbon-containing resource to partly replace the coking coal during the coking process.6–9) Nomura et al.10) investigated the effect of plastic addition on the coal caking property and found that the decomposition products of plastics would interacted with the coking coal during the carbonization process resulting in the decrease of coal caking property and coke strength. Mollah et al.11) had tried to produce blast furnace coke using lignite, its commercial products, and briquettes. However, it was found that the produced coke had high compressive strength but the reactivity was too high to be used in a blast furnace. Previous study showed that there still existed in using lignite to produce coke with various difficulties. Though partial replacement of coking coal by cheaper and more abundant coals could bring great economic and environmental benefits, these coals have little bond and coking property. Such as, lignite was porous, low ordered degree of microcrystalline compared to coking coal. If a large number Influence Mechanism of Lignite and Lignite Semi-coke Addition on Drum Strength of Coke


A high g piezoresistive accelerometer with four-terminal fixed beam-island structure was designed for the purpose of testing in special demand. The weight of the mass and the distance between the center of mass and beams were both decreased by KOH etch at the back of the mass. Combining the calculation of mechanics and the technology, the dimension of the structure was determined. Through the analysis of the stress and the model by Ansys, the sensitivity of the output and the natural frequency of the first model were obtained. In the end, it is testified that the structure can bear transient attack of 20, 000g using transient model analysis. It is concluded that the structure can meet the necessity of design by experiments.


Dusta vrana (Chronic ulcer)  is  one  of  the  conditions  which  have  prolonged  healing  time depending  on  existing  primary  cause.  Many clinical researches are carried out in the management of dusta vrana.  Kshara (caustics alkali) is deemed among the instruments because of specific properties like chedana (exicition), bhedana (incision), lekhana (scraping), and ability to alleviate vitiated three doshas. Acharya Sushruta, explains kshara karma as one of the sixty procedures for management of ulcer and it can also be indicated in dusta vrana. In  clinical  practice, it  was  noted  that  even  after  prakshalana (spraying), dressing  and  other measures of vranaropana (healing measures), vrana remained without healing. Understanding its importance, initiations have been tried to establish the efficacy of pratisaraneeya kshara in dusta vrana through a clinical trial. In this study, five patients have been selected from the OPD/IPD of Shalyatantra Department of Sri Kalabyraweshwara swamy Ayurvedic Medical College Hospital and Research Center, Bangalore, between January 2014 to June 2014, After the approval from the institutional ethical committee.  In this study a clinical trial was made on dusta vrana by the application of Apamarga kshara (caustics prepared from Achyranthes aspera) to initiate the process of healing. Under aseptic precautions, pratisaraneeya kshara was applied on the dusta vrana, Then observed for 100 matra kala (around 35 sec to 1 min)   followed by washing of vrana with fresh lemon fruit juice. Following this, dressing was done with yastimadhu gritha. It was observed that the areas of hypertrophied granulation tissue become soft and the unwanted tissues were separated from their base which was easily removable. Discharges from the wound reduced remarkably, initiating the growth of healthy granulation tissue. The results obtained were found very encouraging.


Let n=p 1…p k, where p′ is are different primes, e be a positive integer satisfying (e,φ(n))=1, and φ(n)=(p 1-1)…(p k-1). By RSA(n,e) denote the RSA-ciphering system with n and e as its public keys. Using Sun Zi's theorem, a method to calculate the fixed point P′s of RSA(n,e), that (P,n)=1, is given. Let T(n,e,α) be the number of α-order fixed points P′s of RSA(n,e), that (P,n)=1, and S(n,e,K)=∏Kα=1T(n,e,α)1K, thenlog S(n,e,K)=ω(n)log2+1K∑p|n∑q|p-1∑rm|qlog rK(ind ge, r m-1(r-1))r m-1(r-1).where r is prime, g is a primitive root of mod rm, and [x] denote the integer part of x.


The accumulation of macrophage foam cells in atherosclerotic lesions is associated with both initiation and progression of this disease. Scavenger receptors CD36 and SRA are the primary receptors responsible for conversion of macrophages into foam cells. Integrin (cid:1) V (cid:2) 3 plays a role in the differentiation of several cell types, but its involvement in the transition of macrophages into foam cells and the potential role of this receptor in atherosclerosis have not been examined. Using an in vitro model of single surface receptor activation by binding with an immobilized monoclonal antibody specific to (cid:1) V (cid:2) 3 integrin we show that ligation of (cid:1) V (cid:2) 3 integrin prevents differentiation of blood monocytes and macrophages into the foam cell phenotype via coordinate down-regulation of CD36 and SRA. This effect of (cid:1) V (cid:2) 3 integrin ligation can be reproduced by contact with endothelial cells, whereas the inhibition of (cid:1) V (cid:2) 3 receptor ligation re-stores the uptake of oxidized low-density lipoprotein. Moreover, we found that (cid:1) V (cid:2) 3 integrin is readily detected in situ on macrophages in early and advanced atherosclerotic lesions and that in vitro exposure to oxidized low-density lipoprotein up-regulates (cid:1) V (cid:2) 3 integrin expression. We hypothesize that (cid:1) V (cid:2) 3 integrin and thus they do not form foam cells as long as the (cid:1) V (cid:2) 3 receptor is activated. Moreover, our data suggest that if other ligands are present in a particular microenvironment that can activate (cid:1) V (cid:2) 3-dependent signaling pathways, the foam cell phenotype may be reversed by down-regulation of scavenger receptor activity ( dotted line ). The prediction from our hypothetical model is that when (cid:1) V (cid:2) 3 integrin is persistently ligated/activated, it will prevent macrophage differentiation into the foam cell phenotype. Conversely, blocking of the (cid:1) V (cid:2) 3 receptor may lead to up-regulation of scavenger receptor expression and increased foam cell formation.


Western societies or does it reflect something special about Sweden? If, as Boholm implies, social class has little relevance for the native models of kinship, what is the significance of that phenomenon? It would be particularly interesting to examine Boholm's proposed kinship model and analyses of kin gatherings in Sweden in the light of data on other Scandinavian societies. Many of the forms of behavior and thought described by Boholm seem quite similar to those found in other Nordic countries, e.g., Finland, yet they also differ subtly. What do those subtle differences imply? These comments should be understood within the context of the pioneering nature of this work. This book is a valuable addition to the literature on modern Western kin-


The Optically-Coupled Current-Mirror (OCCM) is a novel feedback circuit architecture that allows linear transmission of analog signals via optical fibers. Its most distinctive feature is that the input stage is galvanically isolated and passive, as it consists just on the back-to-back connection of a LED and a photodiode. Only those components are required to be in close contact with the detector, and no power supply is required to be brought to the input stage. All active components are located at a safe distance, therefore saving them from being exposed to radiation, as it is common in most experiments at particle accelerators. We have investigated the properties of the OCCM when its passive input stage is cooled to cryogenic temperatures. Results have been extremely interesting as, for instance, the sharp increase in open-loop gain observed when cooling to 77 K, due to an enhanced LED efficiency. This translates into a higher dynamic range and still better linearity, opening new opportunities for the transmission of current signals generated in cryogenic detectors.


The socio-economic impact of telemedicine is no longer to be proven; the perceived benefits are for the patients themselves, for the different practitioners and more broadly for the whole healthcare system. These advantages include for instance improving health care delivery for remote and/or underserved patients, helping distant physicians to make the right decision through second medical opinions and reducing overall costs of healthcare system. Hence in that field, providing innovative and pragmatic solutions/tools for healthcare professionals is one of the main objectives. Through this work, we present some telemedicine applications using Augmented Reality. We also discuss different aspects existing in these applications aiming to help both patients and physicians. We emphasize especially, fifteen works published in relevant conferences and journals. Our goal is to show the benefit of putting Telemedicine and Augmented Reality technologies together for both healthcare services delivery and remote training activities. In particular, we highlight interactive, immersive and collaborative aspects for medical distance training, one of the fields where using augmented reality is highly beneficial and very promising.


Fourier-decomposition of free-breathing pulmonary magnetic resonance imaging (FDMRI) was recently piloted as a way to provide rapid quantitative pulmonary maps of ventilation and perfusion without the use of exogenous contrast agents. This method exploits fast pulmonary MRI acquisition of free-breathing proton (1H) pulmonary images and non-rigid registration to compensate for changes in position and shape of the thorax associated with breathing. In this way, ventilation imaging using conventional MRI systems can be undertaken but there has been no systematic evaluation of fundamental image quality measurements based on linear systems theory. We investigated the performance of free-breathing pulmonary ventilation imaging using a Fourier-based linear system description of each operation required to generate FDMRI ventilation maps. Twelve subjects with chronic obstructive pulmonary disease (COPD) or bronchiectasis underwent pulmonary function tests and MRI. Non-rigid registration was used to co-register the temporal series of pulmonary images. Pulmonary voxel intensities were aligned along a time axis and discrete Fourier transforms were performed on the periodic signal intensity pattern to generate frequency spectra. We determined the signal-to-noise ratio (SNR) of the FDMRI ventilation maps using a conventional approach (SNRC) and using the Fourier-based description (SNRF). Mean SNR was 4.7 ± 1.3 for subjects with bronchiectasis and 3.4 ± 1.8, for COPD subjects (p>.05). SNRF was significantly different than SNRC (p<.01). SNRF was approximately 50% of SNRC suggesting that the linear system model well-estimates the current approach.


Existing methods regarding the influential nodes identification in complex networks usually assume that the structures of the networks are fully known. However, in many cases, knowing the full structure of one network is hard or impossible, and each participant can only obtain the partial structure of the networks. Therefore, each participant can be viewed as a private network (PN) of the original network, and they form multiple PNs. Then, one question arises: how to collaboratively identify influential nodes in multiple PNs while protecting the privacy of each PN. To this end, a secure multiparty computation ranking (SMPC-ranking) method is proposed to solve such an all-new problem based on the secure multiparty computation (SMPC) protocol, in which the SMPC protocol jointly computes a centrality function to measure the comprehensive importance of nodes or their ranking results by integrating each PN's inputs without disclosing their inputs (i.e., the nodes' importance). Experimental results in different networks demonstrate that, no matter what type of the centrality index is, the SMPC-ranking method can better identify the influential nodes in networks than that of the baseline method only using the structural information of one PN. What is more, our SMPC-ranking method does not violate the privacy of each PN. Therefore, the proposed method provides new insights on collaboratively identifying influential nodes in multiple PNs and has potential applications in many fields.


Young rolled leaves of sugarcane (Saccharum sp., variety Co 1007) are cultivated in vitro on a synthetic medium. The first anatomical modifications appear in nonlignified, subepidermal fibers, on the external side of the leaves, by the 3rd day. Cellular growth precedes proliferation. Thereafter the process of dedifferentiation affects all of the tissues of the leaves. Proliferations of epidermal tissue, subepidermal fibers, bundle sheath cells, and vascular tissue give rise, respectively, to the epidermal tissue, peripheral cambial zone, parenchyma, and vascular tissues of the calluses. Thus, organogenic specificity of each foliar tissue is preserved.


A method of tracking the context in man-machine communication is proposed. The "tracking the context" is defined as locating the place of context switching and dividing the user's command sequence into chunks, each of which corresponds to one work. For tracking the context, "a syntactic-context" is introduced. A syntactic-context is a working set of words in the command lines a user enters. To locate the place of the syntactic-context switching, word-kind ratio and window contribution are defined. It is shown that the hit rate of command prediction is improved by using these indicators, which shows the effectiveness of the proposed method.


Background: NCCN's guidelines for the diagnosis and treatment of rectal cancer suggest that accurate preoperative clinical staging of rectal cancer is very important. Reliable preoperative evaluation is the key to the development of surgical protocols, in order to investigate the diagnostic value of digital rectal diagnosis for lymph node metastasis of middle and low rectal cancer. Methods: We prospectively performed digital rectal examination in 258 patients with mid-low rectal cancer before operation, to analyze the distance from the lower margin of the tumor to the margin of the anus, the diameter of the invasion of the intestinal wall of the tumor, the accuracy between the general type and depth of invasion of the tumor and the pathological results of the postoperative specimen, and the predictability of the lymph node metastasis rate of the rectal digital examination. Results: The results of the analysis showed that the above indicators and postoperative pathological findings have high accuracy. Conclusions: It is concluded that accurate and detailed digital rectal examination before operation can predict lymph node metastasis rate of mid-low rectal cancer at a higher level and accurately.


In a π-donor ligand, the SALCs of the ligands are occupied, hence it donates the electrons to the molecular σ σ* and π π* orbitals. The orbitals associated to eg are not involved in π interactions therefore it stays in the same energy level (Figure \(\PageIndex{1}\)). On the other hand, the occupied ligand SALC t2g orbitals that would form molecular orbitals with the metal t2g orbitals (ie. dxy, dxz, dyz) are lower in energy than its metal counterparts. The resulting MO has π* orbitals that are energetically lower than the σ* orbitals that are formed from the non bonding orbitals (eg). The difference between the t2g π* and eg σ orbitals is denoted as Δ, split. In the π-donor case, the Δ is small due to the low π* level.


A comprehensive review of the various studies reported in the literature to date on the mathematical modeling of fixed-bed reactors for the production of fuels by the Fischer–Tropsch synthesis (FTS) was carried out. It is quite clear that most of the proposed models are based on a set of assumptions that allow their wide simplification by reducing the models into forms of low complexity, due to the fact that in most cases the effects of phase equilibrium are neglected, and relatively simple Fischer–Tropsch kinetics of the power law type are used. In addition, most of the proposed modeling schemes neglect the effects of resistances to gas–liquid and liquid–solid mass transfer. On the other hand, few reports consider the energy effects under the consideration of a nonisothermal operation assuming a plug-flow behavior and a gas–liquid system. A generalized model of a fixed-bed FTS reactor is proposed which takes into account all the mass and heat transfer phenomena, as well as hydrodynamics and vapor–liquid ...


This work investigates the effect of different conditions of PFO thermal cracking from two PFO samples on liquid, solid and gas product yield and asphaltene removal efficiency in a new designed experimental setup. No need to use a catalyst, simple operating system and experiment conditions, the ability to use water as a cheap carrier gas and high asphaltene extraction efficiency without the use of solvents are outstanding benefits of this method to upgrade PFO. The yields of the liquid, solid and gas products were compared in various operating conditions and the optimum experimental conditions were obtained. The results revealed the best thermal cracking condition of PFO in terms of liquid yield and asphaltene removal in this setup for samples. The optimum conditions were 390 and 380 °C for reactor temperature of PFO-1 and PFO-2, respectively; 150 °C for temperature of carrier gas and 100 ml/min for carrier gas flow rate. In these circumstances about 70 and 53 wt% of the liquid product, 25 wt% of the solid products, and 5 wt% of the gas product are generated while the asphaltene separation was reached about 95 and 96.5%.


Major John Francis Bourke, M.C., lost his life at sea by enemy action in January. He took the Scottish Triple Qualification in 1913 and served during the war of 1914-18, being mentioned in dispatches in 1916 and receiving the Military Cross. He attained the rank of Major in 1927, and was invalided out towards the end of 1940. He had just served a term of duty in India and was recently stationed at Quetta, and was on his way home when he met his death. He had been


Visceral leishmaniasis (VL) is a protozoan disease caused by some Leishmania donovani complex species and is considered as an endemic zoonotic parasitic disease in Iran. This study was performed to determine the prevalence of human VL in Iran. Data were systematically gathered from 1985 to 2018 in Islamic republic of Iran from the following electronic databases: PubMed, Google Scholar, Science Direct, Scopus, Web of Science, Magiran, Irandoc, Iranmedex and Scientific Information Database (SID). In total, 29 studies reporting the prevalence of VL from different areas of Iran met our suitability criteria. The Q test and the I2 statistics were applied to determine heterogeneities. The Egger's and Begg's test was used to check the presence of publication bias. The pooled prevalence of VL in Iran measured by random-effects was estimated at 1% (95% CI:1 2) in urban areas, 3% (95% CI:2 4) in rural areas and 2% (95% CI: 2-3) in total. The majority of VL cases during the last 33 years were reported in the northwest and south provinces of Iran. There was a high degree of heterogeneity (I2 = 98.2%, Q test: p = 0.0002) and Begg's (z = 3.62, p < 0.001) and Egger's (bias =5.9, 95% CI = 2.70 9.11) tests were significant for the study of publication bias. After correction, the total prevalence was estimated to be 0.3% (95% CI: 0.2 0.9).The prevalence of VL in Iran was 0.3%, and this rate was much higher in the northwest and south of the country. These results are desirable for managing the control programs of this disease.


This paper analyzed the effects of group bibliotherapy in junior high school assigned by Daegu Metropolitan Office or Education as a model school. Seventy seven students haying problems were selected and divided into the two different programs which developed for internalizing problems and externalizing problems respectively. Each bibliotherapy program has been carried out 15 times. The effects of two programs were proved positive and statistically significant. The effect of each program were differ from the other, owing to the purpose and reading materials. The study skewed bibliotherapy are more effective for students having internalizing Problems and female students. Bibliotherapy also affected student`s reading attitude. In order to reach self bibliotherapy, developmental bibliotherapy should be connected to the reading guidance.


A class of solutions to Einstein's field equations, which describe the gravitational field of a bounded distribution of matter, are studied together with cosmological solutions describing the largescale structure of the Universe. It is shown how a cosmological constant changes the properties of a black hole. The spherically symmetric gravitational collapse of a rotating radiating object that experiences mass losses due to shock waves is examined, and black holes in asymptotically flat spaces and in de Sitter spaces are discussed. A homogeneous cosmological model with rotating matter is developed. It is shown how rotation of matter affects the behavior of a homogeneous cosmological solution near a singularity. The problem of the structure of singularities is analyzed. (IAA)


The utility model discloses a cantilever support type power takeoff mechanism, which consists of a torque converter casing, a power takeoff port gear, a gear shaft, bolts, gaskets, a bearing and a retainer ring for a port, wherein the bearing is sleeved on the gear shaft and is positioned by a shaft shoulder of the gear shaft; a bearing and a small assembly of the gear shaft are arranged in an inner hole of a power takeoff port gear; the bearing is positioned again by using a spigot in the inner hole; the retainer ring for the hole is arranged in a retainer ring groove of the inner hole of the power takeoff port gear so as to position the bearing and the gear shaft; and the assembled assembly is fixed on the torque converter casing by using the bolts and the gaskets. With the structure, the cantilever support type power takeoff mechanism is convenient to assemble and disassemble and has high efficiency and low cost.


At present,the 10 million tons refinery around our country and the million tons new expanding project at YiXi have started and already have gone into the critical period,so as to achieve the HSE goal of "zero accident,zero injury,zero pollution",to modify the HSE supervising measures as well.The HSE risk management,worked permitting and emergency response should be strict.The assessment and diagnosis of consultation should be enhanced.The positive incentives and severe punishment on the result of HSE supervision should be taken to realize the overall controlled.


In this work, we present the first results of a PS analysis of InSAR time series referred to the area of Lisbon, Portugal. In particular, the regions of Arruda dos Vinhos and Fanhões-Trancão/Lousa at north of Lisbon were chosen as test sites being characterized by a large number of known landslide phenomena. This application aims to study the feasibility of using InSAR time series as a tool to support the operations of landslide inventory at a regional scale.


GEM of China will be put into practice in the near future. GEM will fully abide by the rules of market in the terms of listing requirements, trading regulations, competitive pricing on the first day and market closing rules. GEM will also have some influences on the main market and investors. Therefor, GEM must be well orientated and strictly supervised to secure the healthy development of GEM.


Combining with open source ComGIS of MapWinGIS,VB.NET and SQL Server,this paper discussed how to embed ComGIS,and how to load layer and manipulate map and measure map and show the shapefile under the envelopment of VB.NET.Meanwhile,it took prototype system as an example and explained the characteristic and application principle of open source GIS software.


Objective To investigate the sensitivity of cholangiocarcinoma HCCC-9810 cell lines to cryptotanshinone;and to evaluate the effects of cryptotanshinone on cell cycle,apoptosis and survivin expression of cholangiocarcinoma cells.Methods HCCC-9810 cell lines were cultured in vitro and treated with cryptotanshinone of different concentrations.The sensitivity of cholangiocarcinoma cell(HCCC-9810) to cryptotanshinone was assessed with cell morphological observation and MTT method.Flow cytometry and RT-PCR were applied for evaluation of cell cycle and survivin mRNA expression,respectively,in HCCC-9810 cells.Results Cryptotanshinone significantly inhibited the proliferation of the HCCC-9810 cells following concentration and time dependent manners.As the optimal treatment spanned,HCCC-9810 cells was caught in G0/G1 phase,with reduced proportion of cells in S phase and increased apoptosis,and the survivin mRNA expression was down-regulated.Conclusion Cryptotanshinone can inhibit the growth of the HCCC-9810 following time and concentration dependent manners,Furthermore,cryptotanshinone induces apoptosis of HCCC-9810 cell,probably via down-regulation of survivin expression and affecting the cell cycle.


Objective:To explore the clinicopathologic features and differential diagnosis of pancreatic endocrine tumor(PET).Methods:The clinicopathologic and immunohistochemical features of 3 PET were analysed.Combined with the literatures,the diagnosis of pancreatic acinar cell carcinoma were identified.Results:The PET cells were solid flake and trabecular shape,acinar-like arrangement and not significant cellular atypia,and rich blood vessels in intercellular substance.Chromogranin A,synaptophysin,and the endocrine markers of insulin were detected by immunohistochemistry.Conclusions:Most PET are benign,but the pancreatic acinar cell carcinoma is highly invasive tumor.The morphology of the pancreatic acinar cell carcinoma is similar to the PET,and the biological behaviors of two types tumor have significantly different,and distinguishing two types of famor has obvious clinical significance.


T CURRENT level of attainment by industry in most of the developing countries is far from satisfactory. This is so, even in the perspective of early industrialisation of some of the now developed countries of the world. And yet, when the industrialisation of these countries was still in its infancy in the latter part of the nineteenth century, there were no advantages of recent revolutions in technology, of the growing complex of international finance institutions, of improved educational facilities, etc.


A vehicular drinking-water apparatus comprises a body and an inner container, wherein, the body is an external shell of the drinking-water apparatus, the inner container is arranged inside the external shell, the upper end of the body is extended outwards and provided with an upper extension section, and the lower end is extended and provided with a lower extension section, extending directions of the upper end extension section and the lower end extension section are reverse, so the external shell is of a Z shape and fixed in a chamber in the vehicle, the top surface of the body is provided with a cover, the top surface of an upper cover is provided with a warming hole, the inside of the upper cover is provided with a close cushion to prevent radiation and liquid overflow, a placement space and two storage spaces are arranged inside the body, inner bottom plates of the storage spaces are inclined plates, the inner container is arranged in the placement space, tea bags or beverage bags are arranged in the storage spaces, the front of the body is provided with a take-out port, which is communicated with the storage spaces, the upper extension section is provided with a water outlet and a water outlet button, the lower extension section is provided with a power switch, a safety switch and an opening, the back side of the body is provided with a water quantity display position, the bottom part of the inner container is provided with a motor, pipes are connected between the motor and the inner container, and between the motor and the water outlet. The utility model can be arranged in various vehicles with perfect effects.


Abstract Dialogue is a category that is central to politics, media, and education, and yet in all of these domains it can be confusing and ambiguous. Starting from a critical framework built on the work of educational philosopher Paulo Freire, we undertake an inquiry into the meaning of dialogical intersubjectivity and its political determinations, with a particular focus on liberal models. We situate this discussion in the context of the rise of radical Right populisms, which have exposed the strength of racial resentment and white supremacy in contemporary politics, and raised questions about the meaning of social cohesion and the relationship between speech and violence. In this context, we show how liberal calls for unity and reflexive defenses of free speech obscure the exclusions and antagonisms that traverse society, while also flattening the meaning of dialogue and betraying its emancipatory vocation. Finally, we suggest that educators should understand their work as continuous with a broader landscape of struggle, and that their interventions should be informed by an awareness of the pedagogical costs of reducing dialogue to a form of talk or method that refuses ethical and political commitment.


Abstract 4546 Introduction: Consolidation with autologous transplantation (AutoSCT) may extend progression free survival when administered following initial induction. Published data suggest intensive cytarabine containing induction may improve outcome when administered prior to autologous transplantation. Methods: We retrospectively evaluated all patients with MCL transplanted at our institution before 2010. We identified 57 patients, among whom 52 were transplanted in first or second remission. Results: 21 patients had received a cytarabine containing induction (most commonly R-HyperCVAD), among whom 14 also received cytarabine as a component of conditioning (BEAM+/−R). The most common induction in the remaining patients was R-CHOP. Among the 31 who did not receive a cytarabine based induction, 23 received cytarabine as a component of the pre-transplant conditioning regimen (BEAM+/−R). The median PFS for those getting cytarbine with induction and conditioning was approximately 28 months (at which time 51% of patients continued without progression). The median PFS for those getting cytarabine with conditioning only was approximately 38 months (at which time 47% continued without progression). Logrank analysis shows no statistically significant difference between these groups (p one-sided = 0.29). Alternatively, those who did not receive any cytarabine had a median PFS of 20 months, with no survival beyond 33 months. Logrank analysis shows this to be inferior to those receiving cytarabine with induction/conditioning (p one-sided = 0.049), as well as among those who received cytarabine with conditioning only (p one-sided = 0.001). Conclusions: In the absence of randomized comparisons it is difficult to draw firm conclusions on the role of induction. These analyses would suggest that among those with chemosensitive disease able to proceed to transplant, more modern conditioning with cytarabine containing regimens may make up for lack of exposure to this agent during induction. Disclosures: Sokol: Celgene: Honoraria, Speakers Bureau.


Objective:To investigate the species and distribution of freshwater crabs,the second intermediate host of paragonimus westermanii in Yongjia county. Methods:The freshwater crabs in Yongjia county were collected by field-investigation for morphology identification to discover new species. Results:There were four major kinds of freshwater crabs in Yongjia county,composed by S. chekiangense,S. yangtsekiense,Nanhaipotamon and Bottapotamon. And the Nanhaipotamon and Bottapotamon were new species. Conclusion:It proves that new species of freshwater crabs existed in Yongjia county,so awareness of the species,infection rate and changes of freshwater crabs can help study the life history of paragonimus westermanii and provide etiological basis for prevention and control of paragonimiasis.


Thank you very much for downloading biological nitrogen fixation in farming systems of the tropics. As you may know, people have search hundreds times for their favorite novels like this biological nitrogen fixation in farming systems of the tropics, but end up in infectious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they are facing with some malicious bugs inside their desktop computer.


2′-(2-Diisopropylaminoethoxy)-butyrophenone (ketocaine) and 1-butoxy-2-(2-diisopropylaminoethoxy)-benzene show a good anaesthetic effect on topical application. The synthesis of both of these compounds specifically labelled with 14C is described. The preparation of ketocaine generally labelled with tritium and specifically labelled with deuterium is also reported.


This study aimed to determine the effect of liquidity and leverage on company profitability. The research method used in this research is a descriptive verificative method. The data used is secondary data, namely the type of data obtained indirectly from the first source (company) in the form of a summary of its performance for six years (2013-2018). The sampling technique used purposive sampling, obtained a sample of 14 companies. The data analysis conducted in this study used panel data regression. After the data was obtained, the classical assumption test was carried out (using the linearity, multicollinearity, heteroscedasticity, and autocorrelation test) with Chow's test and Hausman test. This study indicates that the picture of liquidity is in an unfavorable condition, as well as leverage and profitability are in the unfavorable category, and profitability is not significantly affected by liquidity in a negative direction, while leverage has a significant negative effect on profitability.


In this paper, specimens of channel bolted connections fastened with austenitic stainless steel and tested in order to investigate the ultimate strength and curling behavior. The end distance perpendicular to the loading direction is considered as main variables. As a results, the curling also occurred in the channel bolted connections with a long end distance as previous research concerning thin-walled single shear bolted connection with plane plates. Moreover, the comparison of the fracture mode and ultimate strength are made, and the strength reduction by curling is discussed.


[Objective] To study the effect of Mosla chinensis Maxim on Trichomonas vaginalis in vitro.[Methods] After treated with Mosla chinensis Maxim water extract(MCMWE),Trichomonas vaginalis was observed under light microscope,for the purpose of morphological changes and mortality rate of Trichomonas vaginalis at different time after agent interactions.At the same time,in comparison with the killing effect on Trichomonas vaginalis conducted by Zanthoxylum bungeanum maxim and Dichroa febrifurga Lour.[Result] The killing effect by Mosla chinensis Maxim was positively correlated both with the concentration of agent and the acting time.1∶4(62.5 mg/mL),1∶4 and 1∶1(250 mg/mL) were the minimum effective concentration for MCMWE,Zanthoxylum bungeanum maxim and Dichroa febrifurga Lour to kill Trichomonas respectively.Among the three Chinese herbs,Mosla chinensis Maxim group obtained the best killing effect,Zanthoxylum bungeanum maxim group the secondary and Dichroa febrifurga Lour group the lowest,which was of statistical significance as compared with one another(P0.01).After treated with MCMWE,the cytoplasm of Trichomonas vaginalis was filled with granules and vacuoles,and some of those Trichomonas vaginalis broke and their cellular content overflew.[Conclusion] Mosla chinensis Maxim exhibits a relatively potent effect on Trichomonas vaginalis.


MargaretA.Hamburg,MD, thesecond woman nominated to be commissioner of the Food and Drug Administration (FDA), stepped down from the post in late March, just shy of 6 years on the job. The agency's responsibilities grew withinweeksofHamburgassumingthepost, when President Obama signed a law allowing the FDA to regulate tobacco products. Thespeedofapprovalsquickenedduringher tenure,with the FDAgreenlighting 51 novel drugs and biologics in 2014, the most in almost20years,Hamburgwrote inablogpost February 5 (http://1.usa.gov/19GXDeu). Among the drugs approved in 2014 were 4 novel systemic antibiotics, only 1 less than the number approved the entire previous decade, she wrote. Hamburg had previously served in the US Office of Disease Prevention and Health Promotion from 1986 to 1988 and as assistant director of the National Institute of Allergy and Infectious Diseases (NIAID) from 1989 to 1990. She left the NIAID in 1990 to become New York City's deputy health commissioner, and within a year she was promoted to commissioner. In 1997, President Clinton appointed her to be assistant secretary for policy and evaluation at the US Department of Health and Human Services. Before joining the FDA in 2009, Hamburg worked at the Nuclear Threat Initiative, a foundation dedicated to reducing the threat from nuclear, chemical, and biological weapons. Thedaughterof2physicians,Hamburg, 59 years old, graduated from Harvard Medical School and completed her residency in internal medicine at what is now New York–Presbyterian Hospital/Weill Cornell Medical Center. JAMA met with Hamburg at her office during her last week at the FDA. Shortly after JAMA's interview, the Institute of Medicine announced Hamburg's appointment as its next foreign secretary, where she will serve as a senior adviser on international matters and a liaison to foreign academies of medicine and science. The following is an edited transcript of her interviewwith JAMA.


A hammer drill has a cylinder within a housing with the cylinder forming a piston chamber. A drive piston is reciprocally mounted within the piston chamber and is displaced by a motor. A percussion piston is located within the piston chamber with an air cushion space located between the two pistons. As the drive piston reciprocates, it moves the percussion piston back and forth by way of the air cushion located between them. One of the pistons has a conduit open at one end to the air cushion space and at the other end to the exterior of the cylinder. A closure plug is located in the one end of the conduit and closes off air flow from the air cushion space into the conduit at regular operating temperatures. If the temperature in the air cushion space rises due to air leakage from the space, the closure plug melts and connects the conduit with the air space so that the reciprocation of the percussion piston stops before the pistons strike against one another and cause damage.


Lathe work is the most representative basic manufacturing method and its practice is a required professional course in engineering universities. By learning lathe work practice, students can master mechanical machining operation skills and cultivate innovation consciousness. This paper analyzes the present condition of lathe work practice and presents some suggestions on teaching reform. Based on the suggestions, teaching reform brings significant improvement on students' comprehensive abilities.


In this paper, one of the significant parts of "ASJ Model 1998", i.e. calculation method for sound propagation, is presented. For the factors that affect sound propagation, diffraction, ground effects, meteorological effects, sound reflection are included. The application of the calculation model to roads in various types, such as interchange, semi-underground road, double deck viaduct, road tunnel and road in built-up area is presented. As an additonal contribution to road traffic noise, the treatment of structure noise caused by the vibration of viaduct is described. For the covering abstract see ITRD E107776.


The tremendous recent growth of road traffic worldwide, combined with increasing environmental constraints, makes rapid progress more critical in reducing the fuel consumption of motor vehicles and improving their fuels. Requirements for the formulation of 'ecofuels' include the following. The ecological balance of the proposed ecofuel, compared with existing fuels, must be calculated on the basis of a life cycle. The use of locally produced renewable fuels should be favoured. The technical performance and selling price of existing fuels must be equalled or improved. Worldwide experience has already confirmed the technical feasibility of biofuels production and use, especially for methanol and ethanol. Used as additives to petrol and diesel fuel, biofuels such as ethanol could produce more ecological reformulated fuels. Biofuels still need some public sector support, but have very nearly reached commercial viability. The current 5% target market share for biofuels is consistent with contemporary agricultural policies in France and the European Union. Advantages of biofuels include reducing the environmental impact of transport, by helping to formulate cleaner fuels, and reducing dependency on fossil fuel energy. The author recommends concentrating on the use of biofuels blended at low levels in fossil fuels. For the covering abstract, see IRRD 886884.


This study investigates the potential of gait features as human gait recognition. Firstly, skeleton joints of twenty subjects obtained from Kinect are extracted as features and further selected using the optimized locally linear embedded approach. Next, multi-layer perceptron and support vector machine are employed as classifiers. Result showed that the combination of the optimized locally linear embedded with K=100 and d=94 and support vector machine regularization parameter C=0.001 and linear kernel attained highest accuracy rate in frontal view specifically 96.50% using 94 gait features.


Effective planning of solving problems of pipeline processing of video information in a heterogeneous system on a chip is proposed. It is shown that the heuristic algorithm HEFT has the best characteristics in terms of static scheduling of tasks with the utilization of computing cores by more than 60%.


Knowledge concept recommendation provides more professional service to learners with different backgrounds on Massive open online courses(MOOCs) platforms, which was introduced to track and keep students' interests in a fine-grained view. While some studies construct a heterogeneous information network(HIN) with types of entities and their relationships in MOOCs, which capture the representation of learners and concepts from the HIN to alleviate the influence of the data sparsity, two main limitations in meta-path graph-based knowledge concept recommendation methods hinder the further development: i) Higher-order features of the similarity between learners (concepts) in different meta-paths have not been fully explored. ii) Deviation was found on the distribution of learners' interest.To address the two issues, we propose a novel Knowledge concept recommendation approach called Attentional Meta-path Contrastive Graph Convolutional Networks for Knowledge Concept Recommendation(AMCGRec). Specifically, on each predefined meta-path on the HIN, we introduce the learners (or concepts) and their structural neighbors to construct self-supervision signals, which can capture learners' interest from higher-order features of the similarity between learners (concepts). Then, we use an attention mechanism to automatically adjust the importance of different meta-paths. Finally, we leverage InfoNCE loss as the training objective to alleviate the bias of learners' interest based on interaction data. Extensive experiments on a real-world MOOC dataset show that our proposed AMCGRec outperforms the state-of-the-art other knowledge concept recommendation methods. Our implementation code is available at: https://github.com/omoPucldAMCGRec.


We adopt a three-dimensional discrete element method to investigate the behavior of dense granular materials subjected to constant volume cyclic triaxial shearing. The effect of initial static shear stress on the cyclic response is studied for relatively dense states by cyclic shearing of anisotropically compressed samples. The simulations show two deformation modes of cyclic mobility and residual deformation accumulation depending on the magnitudes of initial static shear stress and the amplitude of cyclic shear stress. By analyzing the axial strain development, we observe that the double amplitude axial strain increases with the number of loading cycles, presumably toward a saturation level in the residual deformation accumulation mode. From the micromechanics perspective, we observe that cyclic mobility mode is associated with a transient collapse of the contact network. In contrast, the contact network remains stable during the shearing process in the residual deformation accumulation mode. RÉSUMÉ Nous adoptons


The exchange behavior of potassium (K) in soils has been extensively studied relative to a dominant cation, which in most cases was considered to be calcium (Ca). Magnesium (Mg) was tacitly assumed that existed in minor quantities or that it had the same exchange behavior with Ca. However, under certain conditions and practices (Mg-rich soils, greenhouse crops) Mg can become an important component of the soil exchange complex participating drastically in the exchange reactions. Consequently, the exchange behavior of the pair K–Mg has merit and in this study the thermodynamics of exchange for this pair were evaluated in two Alfisols with different mineralogical composition of the clay fraction. The exchange reaction was studied in both directions, namely, Mgsoil→Ksoil and Ksoil→Mgsoil. Comparison of the experimental exchange isotherms to the non-preference isotherms revealed that both soils exhibited preference for K relative to Mg. Standard free energies of exchange (ΔG0) for the reaction Mgsoil→Ksoil were negative (−5.7 to −6.7 kJ mol−1) indicating the spontaneity of the reaction and that the formation of a K-soil is favored. Also, ΔG0 values for the reaction Ksoil→Mgsoil were positive (7.3 to 7.5 kJ mol−1) which indicated the reluctance of K-soil to be converted to Mg-soil, thus corroborating the previous findings. Standard enthalpies of exchange (ΔH0) were negative (−8.7 to −13.5 kJ mol−1) for the reaction Mgsoil→Ksoil and positive (13.8 to 15.1 kJ mol−1) for the backward reaction suggesting a strong binding of K with some sites of the soils. Vanselow selectivity coefficients (KV) showed a stronger preference for K in the soil where mica-type minerals dominated the clay fraction. Selectivity for K, as judged by the KV values, was also strongly K-saturation dependent; the lower the degree of K saturation the higher the selectivity for K. Under the conditions of the experiment the exchange reaction of the pair K–Mg was not reversible but exhibited hysteresis, the magnitude of which was more pronounced in the soil where mica-type minerals were prevalent in the clay fraction.


Obtaining consensual solutions is an important issue in decision making processes. It depends on several factors such as experts' opinions, principles, knowledge, experience, etc. In the literature we can find a considerable amount of consensus measurement from different research areas (from a Social Choice perspective: Alcalde-Unzu and Vorsatz [1], Alcantud, de Andrés Calle and Cascón [2] and Bosch [3], among others and from Decision Making Theory: González-Arteaga, Alcantud and de Andrés Calle [4] and González-Pachón [5], Herrera, Herrera-Viedma and Chiclana [7], Herrera-Viedma et al. [6] and Wu et al. [8], among others ). Most of them have a common point, they are based on distances or similarity functions.


It is shown that the results presented in the article 'The influence of the temperature and pressure on a fractal dimension of defects in crystal structures' by V.B. Fedoseev (Butlerov communications. 2010. V23. Number 14. P.36-42) are not correct, because the results are based on impracticable conditions, conflicting assumptions and incorrect distributions.


Introduction.
Planetary Nebulae (PNe) are the descendants of low- and intermediate-mass evolved stars (0.8 - 10 solar masses). Among the astrophysical phenomena, PNe display an impressive variety of complex morphologies, as has been demonstrated by observations obtained in the last years by the new generation of telescopes, e.g. Hubble Space Telescope (HST), Very Large Telescope (VLT), Very Large Array (VLA). PNe show morphologies from spherical to bipolar or multipolar, as well as knots and/or jets collimated at high velocities, reaching 600 km/s in the most extreme cases. Furthermore, it has been estimated that nearly 80% of the PNe are not spherical, a controversial result since PNe are formed from the spherical envelope ejected of an asymptotic giant branch (AGB) star and ionized afterwards by the UV photons produced by its central star.
The shaping of asymmetrical planetary nebulae is yet under debate since these objects defy the standard models for the formation of spherical or elliptical PNe. The onset of the asymmetry of PNe is expected to occur during the short transition from the late AGB and early post-AGB phase. Consequently, a proto-PN frequently displays a bipolar or multipolar morphology, like the proto-PN AFGL915 (The Red Rectangle) or the two young PNe M2-9 (The Butterfly Nebula) and Mz 3 (The Ant Nebula). The existence of disks and/or torii in the equatorial regions and high velocity jets has been proposed to sculpt such morphologies in PNe, since the stellar radiation pressure is not able to collimate these extremely axisymmetric morphologies.
The study of disks and jets as shaping agents of PNe requires the use of high-resolution observational techniques able to observe and resolve the innermost regions of post-AGB sources, proto-PNe, and young PNe. Furthermore, these innermost regions are often embedded in dust and are thus optically thick, nonetheless they emit copiously at infrared (IR) and radio wavelengths.
Motivation and aims.
This PhD thesis aims to prove high-resolution observational techniques using new generation telescopes, as is the case of the 8.2m VLT, to observe in the IR post-AGB, proto-PNe, and PNe at high-resolution. Based in previous studies, we have selected different samples of compact sources in transition to the PNe phase, as well as young PNe in which their innermost regions, where the shaping mechanism lays, were not resolved due to the lack of resolution. In addition, we have selected axisymmetric sources whose innermost zones have been observed and modeled. We aim to prove and compare previous results with the ones obtained using a spectroscopic high-resolution technique applied to the search of the shaping mechanism of extremely axisymmetric PNe.
Considering the characteristics of the evolved stars studied in this thesis, beside the use of powerful instruments capable to achieve high-resolutions, they must also be able to observe structures embedded in dusty environments, since post-AGB stars are important dust producers. These conditions also favour the apparition of molecules whose emission are mainly detected towards IR.
Inspired by all these facts, we aim to obtain observing time using two instruments of the VLT: VISIR (VLT Imager and Spectrometer for the mid-IR) and CRIRES (Cryogenic high-resolution Infra-Red Echelle Spectrograph).
Results and conclusions.
Among all post-AGB objects, the most heavily obscured ones might have escaped the selection criteria of previous studies that detected extreme axisymmetric structures in young PNe. Since the most heavily obscured post-AGB sources can be expected to descend from the most massive PN progenitors, these should exhibit clear asymmetric morphologies. High-resolution observations of these sources should reveal marked bipolar morphologies, confirming the link between progenitor mass and nebular morphology. We have obtained VISIR-VLT mid-IR images of a sample of four heavily obscured post-AGB objects that are barely resolved in previous Spitzer IRAC observations in order to analyze their morphology and physical conditions across the mid-IR. The images obtained in four different mid-IR filters have been deconvolved, flux-calibrated, and used to construct RGB composite pictures as well as color (temperature) and optical depth maps that allow us to study the morphology and physical properties of the extended emission of the sources in our sample. We have detected the extended emission from the four objects in our sample and resolved it into several structural components that are greatly enhanced in the temperature and optical depth maps. The morphologies of the sample, as well as their physical conditions, reveal the presence of asymmetry in three young PNe (IRAS 15534-5422, IRAS 17009-4154, and IRAS 18454+0001), where the asymmetries can be associated with dusty torii and slightly bipolar outflows. The fourth source (IRAS 18229-1127), a possible post-AGB star, is better described as a rhomboidal detached shell. The heavily obscured sources in our sample do not show extreme axisymmetric morphologies. This is at odds with the expectation of highly asymmetrical morphologies in post-AGB sources descending from massive PN progenitors, which is otherwise supported by observations of bright mid-IR unobscured sources. The sources studied may be sampling critical early phases in the evolution of massive PN progenitors, before extreme asymmetries develop.
On the other hand, the young PN K3-35 represents a unique case where a small-sized water maser ring has been linked to the launch of collimated outflows that would be shaping the nebula.
The contrasting optical and radio continuum morphologies of K3-35 indicate that they disclose different structural components which are apparently unconnected. To bridge the gap between optical and radio continuum observations, we present here new broad- and narrow-band near- and VISIR-VLT mid-IR images of K3-35. These images, and their comparison with optical and radio continuum images, are revealing. The radio continuum and mid-IR images are dominated by a compact source at the core of K3-35 whose emission gives evidence of very dense ionized material embedded within a dust cocoon. The emission from the core, obscured at optical wavelengths, is faintly detected in the Ks band. We suggest that the dust may shield the water molecules at the inner ring from the central star ionizing radiation. The precessing collimated outflows, very prominent in radio continuum, are also detected in mid-IR, very particularly in the [S IV] image. The mid-IR emission from these outflows consists mostly of ionized material, although the broad-band filter at 11.85 m seems to imply that a small amount of dust may be carried out by the outflow. The interactions of these outflows with the nebular shell result in shocks which excite the emission of H2 and low-excitation lines from ionized species such as [N II] at the tips of the outflows.
Regarding the spectroscopic observations here presented, we have used and analysed high-resolution long-slit spectra from CRIRES-VLT commissioning time. These data have been used to investigate the implementation of the observational technique known as high-resolution spectro-astrometry, not used before in this research field. We have selected the spectro-astrometry technique motivated by the limitations of the IR interferometric techniques in the study of the asymmetries of PNe. High-resolution spectro-astrometry technique using CRIRES-VLT has proven its efficiency in the search for proto-planetary disks. CRIRES-VLT commissioning data of the proto-PN IRAS 17516-2525 and the young PN SwSt 1 have been used to develop the methodology and tools needed to apply the spectro-astrometric analysis to sources transiting towards or at early stages of the PN phase. Previous studies lacked the spatial resolution required to disclose the morphology of these two sources. Our exploratory study using CRIRES-VLT commissioning data has revealed small sized structures after the spectro-astrometric analysis of these two sources. The structures found in SwSt 1 have sizes of 230 mas in the [Fe III] line and 130 mas in the Brackett gamma line. As for the proto-PN IRAS 17516-2525, the spectro-astrometric signal can be interpreted as compact bipolar lobes of 12 mas in size arising from the innermost regions. In the second phase of the implementation of the spectro-astrometry technique we have obtained observations carefully planed aiming to prove the feasibility of this technique in the search of disks and other compact innermost structures in extremely axisymmetric PNe. We have selected the well studied proto-PN AFGL915, from which past studies have provided strong evidences of a Keplerian gaseous CO disk as well as a disk of crystalline silicates aligned with its minor axis of symmetry. Based in the previous studies and in the C/O chemistry of this source, we have acquired CRIRES-VLT high-resolution spectra of the near-IR CO fundamental band at 4.99 microns. The spectro-astrometric analysis has revealed the following preliminary results. The spectro-astrometric signatures and the line profiles of the 12CO isotope (4.99 microns) resemble Keplerian sources. The presence of a thick torus-like orientated along the minor axis of symmetry, that is, at 101o, has been also disclosed by the spectro-astrometric analysis. These results are in concordance with previous observations representative for the outermost regions of the Keplerian disk and with models predicting the existence of this thick toroidal structure at the innermost regions of AFGL915, whose origins are related with the common envelope binary system progenitor. It has been proposed that this thick innermost torus is massive and is accreting material. Finally, we emphasize that these results must be properly modeled in order to corroborate the properties of the disk found by our spectro-astrometric analysis at the central region of AFGL915.


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In this paper we propose a probabilistic approach to retrieve video clips similar to a given query video clip. In our approach the video clips are partitioned into video segments based on their content homogeneity, and video segments in the database are connected to construct candidate clips and compared with the query clip for their similarity (or distance) during the query process. An efficient scheme is developed to estimate the probability density functions of the distances between the candidate clips and query clip, and based on these density functions, two methods are devised to reduce the number of candidate clips for comparison to speed up the retrieval process. Experimental results show that our proposed approach can notably speed up the retrieval of similar video clips, while maintaining high retrieval accuracy.


Objective
To explore the value of the constructed prognostic prediction model of resectable lung cancer in predicting the survival and prognosis of patients.

Methods
A total of 2 267 patients with primary lung cancer in Shanxi Provincial Cancer Hospital from January 2007 to September 2018 were selected. All patients underwent primary lung cancer surgery without a second primary tumor. Gender, age, occupation, tumor site, pathological type, surgical path, surgical method, tumor stage and treatment were selected as the prognostic factors. A Cox proportional hazard model was used to construct a prognostic index (PI) equation to calculate the PI value of each patient. According to the different ranges of PI values, the low-, intermediate- and high-risk prognosis groups were divided, and the survival status of three groups were evaluated.

Results
Gender (RR= 0.684, P= 0.001), age (RR= 0.591, P -0.5 was the high-risk group, and the differences of their survival rates were statistically significant (P < 0.05). The 1-, 3-, and 5-year survival rates for the low-, risk groups were 96.8%, 87.0% and 77.9%; the intermediate-risk group were 91.8%, 82.2% and 61.7%; the high-risk group were 86.5%, 61.7% and 50.3%. respectively.

Conclusion
The prognostic prediction model of resectable lung cancer can predict the prognosis risk and the corresponding survival rate of patients with resectable lung cancer, and it can help clinicians to evaluate the prognosis and formulate subsequent treatment plans.

Key words:
Lung neoplasms; Thoracic surgical procedures; Prognosis; Models, genetic; Survival analysis


To investigate cardiovascular (CV) performance status several years after early‐onset (EO) or late‐onset (LO) pre‐eclampsia (PE), using echocardiography to assess myocardial strain and left ventricular (LV) torsional mechanics and ventricular–arterial coupling (VAC).


The photocatalytic efficiency of the recently synthesized TiO2 powder, named
 P160, of the degradation of dye Dye C.I. Reactive orange 16 in natural and
 artificial seawater was investigated in comparison to its efficiency in
 deionized water and the efficiency of a standard TiO2 powder Degusa P25. It
 was shown that the photocatalytic efficiency of P160 was slightly higher
 than that of P25, probably due to slightly higher specific surface area,
 higher pore volume and larger pores of the powder P160. The efficiency of
 both photocatalysts in natural and artificial seawater was significantly
 lower than that in deionized water. The overall rate of dye degradation for
 both types of photocatalysts is litle higher in artificial seawater than in
 natural seawater, which shows the influence of organic compounds naturally
 present in seawater on the photocatalysts activity. A saturation
 Langmuir-type relationship between the initial degradation rate and the
 initial dye concentration indicates that the adsorption plays a role in the
 photocatalytic reaction. The photodegradation rate constant k, which
 represents the maximum reaction rate, has similar values for P25 and P160 in
 all types of water due to the similar properties of the photocatalysts. [Projekat Ministarstva nauke Republike Srbije, br III 45019]


The cause of amyotrophic lateral sclerosis (ALS), a cruel neurodegenerative disease, remains unclear. Trans-activating response region (TAR) DNA-binding protein of 43 kDa (TDP-43) has been suggested to have an important role in ALS pathogenesis. In this thesis, we show that a disease linked mutation in matrin 3 (MATR3), a DNA/RNA-binding protein, corresponds to an increased tendency for TDP-43 to aggregate into large and more numerous cytoplasmic inclusions that are the hallmark of ALS. Immunocytochemistry experiments show that MATR3 colocalizes with TDP-43 in vitro . These experiments also show TDP-43 is a component of both MATR3 granules and stress granules, and that MATR3 inclusions are directly adjacent to stress granules or eIF3 α inclusions. We hypothesize that, while not being a part of stress granule complex, MATR3 granules are involved in RNA processing via the stress granule pathway by relaying crucial components such as TDP-43. We have also found that compound 8J is able to disaggregate and relocate TDP-43 and MATR3 positive inclusions in vitro . While the mechanism of action of compound 8J remains unclear, fluorescence activated cell sorting (FACS) experiment showed that there was a significant increase in viability in double wild type (matrin 3 and TDP-43) cells when treated with C8J (p-value <.001), which suggests that the TDP-43 and MATR3 cytoplasmic inclusions that were previously observed have a net cytotoxic effect. Together with the in vitro result on C8J, this result


To obtain the predictive value of microalbuminuria (UMA) for diabetic retinopathy (DR) by investigating the influence of UMA on the incidence of DR. The laboratory and clinical data of 512 type 2 diabetes mellitus (T2DM) patients were systematically collected and evaluated. Receiver operating characteristic (ROC) curve was used to determine the optimal cut-off value. The area under the ROC curve of UMA for incidence of DR was 0.730 [95% confidence interval (95% CI), 0.689 to 0.768], with a sensitivity of 67.8% and a specificity of 70.2%. The increase of UMA level was significantly correlated with duration of diabetes mellitus (DDM), fasting blood glucose (FBG), serum Hemoglobin A1c (HbA1c), triglycerides (TG), low-density lipoprotein (LDL) and DR in T2DM patients (all P < 0.05), bringing about that was a significantly risk factor for the development DR [Odds ratio (OR) 4.357, 95% CI 3.334 to 6.970, P < 0.001]. UMA was an important risk factor of DR, and it is recommended to add UMA as a follow-up project for T2DM patients.


The transitions of biodiversity policies in national environmental policies and/or of the influence of national trends on local plans have been clarified by the other previous researches gradually. However, recently many local governments have been discussing local biodiversity strategies based on Japan's Basic Law on Diversity. In order to consider effectual quantitative information for biological diversity policy at the local government level, this study focused on extracting quantitative information used in basic environmental initiatives by local governments including all of cities designated by government ordinance, which could indicate the natural environment, and examining its characteristics and roles. As a result, it was clarified that many local governments set numerical targets for a large number of policies, and indicated concrete administrative action for the future. On the other hand, the information on the state of the environment for policy evaluation was limited, and the policies had not reached a stage where evaluation was possible on how they contributed to maintaining the environment. Also, it was suggested that the effectual quantitative information could be different by the space scale of each plan for nature conservation.


At the mining of stratigraphy schemes of the Sarasinsky graben it is established that the first primofilices plants in the Altai territory appeared in the Early Emsian circle. The richest site of the fossil plants is located in the northeast of Basargino in 1 150 m below the mouth of the Cheremshanka on the right bank of the B. Kyrkyly River in the break of the Basarginskaya suite. Here A.R. Ananiev defined psilophytes Psilophytites rectissimus Hoeg, Protobarinophyton obrutschevii Ananiev, Psilophyton goldschmidti Halle, Zosterophyllum cf. myretonianum Penhallow, cf. Sciadophyton Laxa Dawson., Drepanophycus sp. in Yu.S. Nadlers collection in 1973. Besides, Minusia antique Tschirkova, Drepanophycus gaspianum Dawson Kraisel et Weyland), Matarakia inopinata Tschirkova were defined in V.N. Korzhnevs collection in 1972-1974. In addition from V.P. Udodovs collection of 1975, Psilophyton arouatus (Halle), Rebuchchia mucronata (Magdefrau), Protolepidodendron scharianum Krausel (Krejci) Kr. Et W., Jeniseiphyton rudnevae (Perecvetov) Ananiev, Gliptophyton granulare Kryschtofovich, Barrandeinopsis beliakovi Krysht were singled out. This collection of fossil plants is stored in the Palaeontology Museum of Tomsk State University. The volcanic-sedimentary rocks of the Emsian contain: 1. Protolepidodendron scharyanum (Krejci) Kr. et W. in Basargiynskaya suite of the Sarasinsky graben, a very popular kind for the middle Devonian and Gliptophyton granulare Krichtofovich, known only from the middle Devonian. 2. Сephlopteris (?) praecox Hoeg typical for the middle Devonian in Ongudayskaya suite of the Ongudaysky graben defined by A.R. Ananiev from A.F. Belousovs collection in 1967. The same mixed vegetative complexes of the Emsky circle are known in other areas of the western part of the Altai-Sayansk folded area. The formation process of primofilices florae was not uniform. In the Emsian an intensive volcanic eruption occurred on a side of the Siberian Continent. In the western areas of the Altai territory volcanism was islandarc. In the eastern areas of the Altai territory within the Uimensko-Lebedskaya zone a marginal-continental rift was formed. The volcanism was accompanied by the formation of gold deposits, polymetals, uranium, which caused mutations of plants. Hydrogen, methane, oxide carbon, carbon dioxide, nitrogen, ammonia, chloride hydrogen, hydrogen sulfide, arsenic and boric acids, chlorides, fluorides of metals delivered by volcanoes in environment promoted occurrence of connections causing epigenetic variability of plants. The factor of natural selection played an important role caused by the change of the living conditions. Aridization promoted the disappearance of primofilices flora, whose separate representatives existed in the coastal zone of continents until the end of the middle Devonian. The possible area of occurrence of primofilices flora can be the coastal areas of the Siberian continent, in particular of the Altai territory.


The problem of steelmaking and continuous casting rescheduling is the key problem in the steel production scheduling. Aiming at the problem of steelmaking and continuous casting rescheduling under strong disturbance of task in this paper, a fast and efficient hyperheuristic genetic algorithm is proposed to minimise the difference degree before and after the scheduling adjustment as the objective function. In the framework of the hyperheuristic algorithm, the high layer strategy is designed as a self-learning heuristic rule selection strategy, the low layer design is a series of genetic operators related to steelmaking and continuous casting scheduling, optimal solution of update iteration by searching for each other through high and low two layers of strategy in the effective threshold. Simulation experiments show that the effectiveness of the algorithm can meet the needs of real-time and stable production to the maximum extent.


ABSTRACT Employing Julie Sanders' theoretical frame, which sets a clear-cut distinction between adaptation and appropriation, this paper argues that Gabriel García Márquez's One Hundred Years of Solitude, as represented by the idiosyncratic pursuits of the character of Colonial Aureliano Buendia, appropriates the Narcissus myth. The proposed appropriation of the Narcissus myth invokes the myth of grounding, which ultimately situates the novel in an apocalyptic world that not only resonates with irony but also helps negotiate the social and political implications of the history of Colombia, which serves as a macrocosm that mirrors the disillusioned life of Colonial Aureliano Beundia. The Narcissus myth, capturing the capricious narrative of grounding in miniature, dramatizes García Márquez's ironic representation of a hero and a nation who, like Narcissus himself, internalize a deterministic reality.


A wavelet multi-component decomposition algorithm has been used for data analysis of micro-Raman spectra from human biological samples. In particular, measurements have been performed on some samples of oral tissue and blood serum from patients affected by pemphigus vulgaris at different stages. Pemphigus is a chronic, autoimmune, blistering disease of the skin and mucous membranes with a potentially fatal outcome. The disease is characterized histologically by intradermal blisters and immunopathologically by the finding of tissue bound and circulating immunoglobulin G (IgG) antibody directed against the cell surface of keratinocytes. More than 150 spectra were measured by means of a Raman confocal microspectrometer apparatus using the 632.8 nm line of a He-Ne laser source. A discrete wavelet transform decomposition method has been applied to the recorded Raman spectra in order to overcome related to low-level signals and the presence of noise and background components due to light scattering and fluorescence. The results indicate that appropriate data processing can contribute to enlarge the medical applications of micro-Raman spectroscopy.


A kind of taxi safety monitoring system and method with public safety monitoring intelligent ceiling light, system comprises a monitor supervision platform, this monitor supervision platform respectively with vehicle-mounted terminal and state security department's supervisory system wireless connections and communicate, ceiling light is intellectual ceiling light, is provided with the video acquisition device and audio collecting device that are connected with vehicle-mounted terminal respectively in it. Method comprises: taxi is in the process of moving, surrounding enviroment public security information is gathered by video acquisition device and audio collecting device, and information is transferred to vehicle-mounted terminal, information is sent to monitor supervision platform by vehicle-mounted terminal, information is sent to state security department's supervisory system by monitor supervision platform, state security department's supervisory system differentiates to confirm that backward monitor supervision platform sends monitored instruction, by monitor supervision platform Long-distance Control ceiling light, to the region implementation focus monitoring that case occurs. The present invention can travel at taxi and gather periphery public security information in way in real time, and implements effective monitoring when there is case involving public security or incident of violence.


Concerning the prohibited or obligatory actions for perpetrating or abandoning of which no punishment has been established, the act of determining discretionary punishment is entrusted to the Muslim judge. An important and meaningful question is raised here as to whether this kind of punishment would include all the unlawful actions and abandoning? In other words, are all legal sins and misdemeanors legally punishable or the Muslim judge would announce just a part of it as punishable?
According to the generally accepted legal viewpoint, the legal judge can, if he deems it expedient, penalize (practice ta'zīr on) the one who has perpetrated an unlawful (ḥarām) act (and some maintain that the unlawful act has to be a cardinal sin), but ta'zīr should be less at a lower level than ḥadd (legal punishment). The renowned majority of Imāmī and Sunnī jurists have accepted this theory. In contrast, some jurists, including Muḥaqqiq Ardabīlī, have cast doubt on the judgment itself that any unlawful act deserves to be punished through ta'zīr. Some contemporary jurists have also concluded that there is no reliable evidence that the perpetrator of any unlawful act would deserve ta'zīr. Some have, even if accepting the judgment itself, interpreted the extent of ta'zīr in such a way that it would include admonition, advice, reproach, and threat, as well.
It is attempted in this article that while making an analytical statement of the viewpoints of the two sides, the viewpoints of the jurists who agree with this judgment to be seriously criticized and to prove with a dominant legal perspective that there is no
jurisprudential or legal evidence for discretionary punishment of any unlawful act and consequently, this viewpoint is not to be easily taken as a foundation for legislation.


Sanjad-Sakati Syndrome (SSS) is a rare syndrome, discovered in Saudi Arabia in 1988. This syndrome is characterized by congenital hypoparathyroidism, severe growth retardation, dysmorphic features, mild to severe mental retardation as well as recurrent chest infections. We presented an eight-year-girl with SSS, with severe growth retardation, mental retardation, resolution of recent chest infection together with a history of bronchial asthma, dysmorphic features, limited mouth opening, micrognathia as well as high susceptibility to difficult intubation. The objective of this case report is to present the successful anaesthetic management of a rare genetic endocrinal syndrome.


When the First International Conference on Hypermedia and Interactivity in Museums was being organized in 1991, the concept of interactive multimedia systems was equivalent to single workstation kiosks with drives that read videodisks or the new CD-ROM technologies. The debates of the day were about whether digital or analog storage provided better assurance for the future and about how best to install the kiosks within museum exhibits. By the 1993 conference the focus had shifted to CD-ROM publications, reflecting the widespread sales of computers with CD-ROM drives and the victory of digital over analog. The debates that raged hottest were about intellectual property and about distribution avenues. Here we are two years later and we find the focus of the ICHIM Conference has shifted again. This time the emphasis is on remote access to interactive multimedia, made possible in the past year by the explosion of the World Wide Web which didn't even exist when we held our meeting in 1993. The papers in this volume reflect the evolution of mechanisms for delivering interactive multimedia, the new social and institutional arrangements they engender, and the continuing importance of the underlying issue of intellectual property. We are witnessing an explosive growth in the size of the potential audience for each of our multimedia products that is brought about by the method of distribution rather than by any investment on the part of museums. Even the best kiosk implementation in the busiest of museums would have been seen by fewer that 500 people a day, while CD-ROM's would be likely to reach several thousand people over a longer period of time and the World Wide Web sites of many museums attract as many as 10,000 visitors a week. But the more important implication lies directly below the surface-these new visitors are people outside our traditional constituency. Reaching them not only means exploiting new delivery mechanisms, it mean new collaborations and partnerships. It means working together with other cultural institutions, working together with other professionals within our museums, and working to identify new sources of technology support and money and to forge successful relations with them. This is, of course, a great opportunity, but it is also a significant challenge.


The design and analysis of the large span steel latticed shell structure in site of Yuyao TianLuoshan is introduced, and some key problems are dwelled on in this paper. By the geometrical nonlinear finite element method, the nonlinear stability analysis is carried out. The buckling modal and the whole course of instability are shown by two analysis method, the eigen-buckling analysis and the geometrical nonlinear finite element method. The influence of spring support to the stability of the structure is analyzed. It is shown that the structure has good wind-resisting capacity, which is fit to the circumstance near sea with lots of typhoon. Large compressive membrane stresses arise in the structure under the condition of temperature rise, leading to a significant reduction in the stability load-carrying capacity of the structure.


We report 17 draft genomes for 14 unidentified Veillonella sp. strains closely related in 16S rRNA gene-based phylogeny and type strains of 3 Veillonella species with the aims of deciphering relationships between related species, evaluating the accuracy of current thresholds for species delineation, and robustly describing new species in the genus. ABSTRACT We report 17 draft genomes for 14 unidentified Veillonella sp. strains closely related in 16S rRNA gene-based phylogeny and type strains of 3 Veillonella species with the aims of deciphering relationships between related species, evaluating the accuracy of current thresholds for species delineation, and robustly describing new species in the genus.


An aim of this article is to present the Catholic social teaching in regard to one basic institutions of economic life that is the market. The analysis starting point is an Encyclical of Pope Leo XIII, Rerum novarum, who initiated Catholic social teaching. All the social encyclicals were studied, which directly or indirectly refer to the market category. In the final part of the article, a synthesis of teaching the Catholic Church in market terms was carried out.


Wavelet analysis is relatively new developed mathematical tool for many problems. Wavelets permit the accurate representation of a variety of functions and operators. More over wavelets establish a connection with fast numerical algorithms. In this paper, Chebyshev wavelet collocation method is developed for the numerical solution of differential equations. Numerical examples are presented to verify the efficiency and accuracy of the proposed algorithm.


This Ph.D. thesis is about causality in Quantum Mechanics, namely about the possibility to provide a
causal explanation for quantum Einstein – Podolsky – Rosen (EPR) correlations.
The well-known interpretation of the Bell's Theorem by Bastian Van Fraassen, who inferred that
quantum correlations cannot be embedded in any causal model, compels us to suppose that
microscopic nature cannot have a causal structure and that causality is an anthropological concept.
However, this interpretation is not commonly accepted and this doctoral thesis is the first general
overview of some recent works about causal explanation for EPR correlations. Particularly, it analyses
the possible causal explanations for the EPR/Bohm experiments by means of the Hans Reichenbach's
model, by means of backward causation models, and by means of models that imply a direct causal link.
In order to do it, it pays particular attention to the Relativistic space-time features and it considers the
studies in the History of Philosophy about the link between causal arrow and temporal arrow.
Moreover, this work aims to endorse the idea that the best way to explain EPR/Bohm correlations
causally is to adopt an indeterministic non-Reichenbachian common cause model, particularly
Cartwright's general forks model.
My conclusion is that causal models for quantum correlations remain viable, and that there is no
contrast between genuinely indeterministic interpretation of Quantum Theory and causal explanation,
with the philosophical implication that the Causal Realism is still acceptable.


13 Groups of C20 concrete specimens and 11 groups of C60 concrete specimens adding different content of fly ash and slag powder, comparing with normal concrete specimens, were tested to analyze compressive strength and workability. The test results show: When adding fly ash only, equivalent replacing volume should not exceed 30%, and for lower strength concretes (such as C20) the adding volume should be lower than 30%, otherwise, the compressive strength was influenced greatly. When adding slag powder only, the replacing volume should increase to 40%, meanwhile the workability must be supervised. When adding fly ash and slag powder simultaneously, the adding volume should reach to 50%, and the ratio of fly ash to slag should be controlled. For C20 concrete the ratio of fly ash to slag powder should not exceed 10% and for C60 concrete the ratio should reach to 25%.