Environmental disturbance on freshwater ecosystems significantly impacts all levels of the trophic web. Salinity in lentic freshwater ecosystems, as a consequence of climatic changes, is rising concern in the scientific community. These alterations affect water quality, the composition and diversity of the aquatic communities. This study aimed to assess the seston quality of two lentic ecosystems, Crestuma reservoir and lake Vela, and evaluate the effects of salinity on food performance of Daphnia magna and Daphnia longispina (isolated from the referred ecosystems). Feeding inhibition tests were used to conduct these two evaluations. Physical and chemical water classification revealed a poor or good ecological potential of the two lentic ecosystems, according to WFD approach. To evaluate seston quality, filtered and unfiltered water samples from the lentic ecosystems were used as treatments. Although only summer samples from Crestuma presented good water quality, the results from the feeding inhibition tests showed that seston from lake Vela presented more nutritional quality. Concerning the assay to evaluate the salinity effect on Daphnia spp., a significant reduction in the filtration rate was observed. The NOEC value was 0.7 g/L NaCl and 0.8 g/L NaCl for D. magna and D. longispina C and V, respectively. The LOEC value was also distinct between species, being 1.0 g/L and 0.9 g/L, respectively. This work allowed to verify that feeding inhibition tests are not sensitive enough for assess the quality of natural waters. However, these tests are economically viable and have high sensitivity to evaluate NaCl effects on Daphnia spp.


By the late 1970s, nonvalvular atrial fibrillation was identified as an independent risk factor for stroke (1-4), and millions of people with this common cardiac dysrhythmia were designated as having substantial risk for cardiogenic embolism (5). One of every six strokes occurs in a patient with atrial fibrillation, and about 10% of all ischemic strokes are probably due to embolism of left atrial thrombi. In the past decade, randomized clinical trials assessed the efficacy of antithrombotic therapies for stroke prevention in patients with nonvalvular atrial fibrillation. Eighteen trials involving more than 10 000 participants with atrial fibrillation have compared anticoagulants and antiplatelet agents, alone and in combination, with placebo and with each other (6). The remarkable pace of development has revolutionized management of this long-neglected dysrhythmia and makes detection of atrial fibrillation an important opportunity for stroke prevention. We present recent advances, discuss controversies, and explore new ideas about stroke and its prevention in patients with nonvalvular atrial fibrillation. We searched the MEDLINE database using the key words atrial fibrillation, thromboembolism, antithrombotic therapy, anticoagulation, stroke, warfarin, and aspirin. Antithrombotic Therapy for Stroke Prevention Adjusted-dose warfarin is highly efficacious for prevention of stroke in patients with atrial fibrillation (Table 1). Meta-analysis of six randomized trials that considered all stroke (both ischemic and hemorrhagic) according to the intention-to-treat principle showed a relative risk reduction of 62% (95% CI, 48% to 72%) for adjusted-dose warfarin compared with placebo (6). This relative risk reduction was similar for both primary and secondary prevention and for both disabling and nondisabling strokes. According to on-treatment analysis (which excludes patients who were not taking warfarin at the time of stroke), the efficacy of warfarin for prevention of ischemic stroke exceeded 80%. Thus, adjusted-dose warfarin has the remarkable potential to reverse almost entirely the increased risk for cardioembolic stroke that accompanies atrial fibrillation. Table 1. Antithrombotic Therapies for Stroke Prevention in Atrial Fibrillation: Key Results of Meta-Analysis of 16 Randomized Trials Anticoagulation increases the frequency and severity of major extracranial and intracranial hemorrhage; intensity of anticoagulation and patient age are the strongest, most consistent predictors of major bleeding (7-10). The benefit of anticoagulation was not substantially offset by major hemorrhage in the randomized trials, in which participants with a mean age of 69 years were carefully selected on the basis of absence of risk factors for bleeding and were managed according to strict clinical protocols. It is unclear whether the relatively low rates of major hemorrhage observed in clinical trials apply generally to patients with atrial fibrillation in clinical practice (whose mean age is about 75 years) (5, 11). Additional studies of the tolerability of anticoagulation in elderly patients with atrial fibrillation are needed. The target intensity of anticoagulation involves a tenuous balance between prevention of ischemic stroke and accentuation of major bleeding. Achieving the lowest adequate intensity of anticoagulation is particularly important for elderly patients, who have higher risks for bleeding. Maximum protection against ischemic stroke in atrial fibrillation is probably achieved by maintaining the international normalized ratio (INR) between 2.0 and 3.0 (12-14). International normalized ratios between 1.6 and 2.5 are associated with substantial, if incomplete, efficacy, estimated to be 90% of that achieved with higher-intensity anticoagulation (15). Two randomized trials with target INRs between 1.4 and 2.8 (estimated mean achieved INR, 2.0 to 2.1) reported the largest relative risk reductions for ischemic stroke in patients with atrial fibrillation (16, 17). Preliminary results of a recent trial in which patients with atrial fibrillation and previous stroke were randomly assigned to target INR ranges of 2.2 to 3.5 compared with 1.5 to 2.1 found a greater rate of major hemorrhage with higher-intensity anticoagulation (18). For patients with nonvalvular atrial fibrillation, INRs from 1.6 to 3.0 are efficacious and relatively safe. For most patients younger than 75 years of age and for secondary prevention, we aim for an INR of 2.5 (target range, 2.0 to 3.0); for primary prevention in most older patients, we seek a lower target INR of 2.0 (target range, 1.6 to 2.5). In recent clinical trials, INRs achieved during follow-up were more often below than above the target range. Low-intensity anticoagulation requires special efforts to minimize the time spent below the target range (during which protection against stroke is sharply reduced). Aspirin offers modest protection against stroke for patients with atrial fibrillation. Meta-analysis of six randomized trials showed a relative risk reduction for all stroke of 22% (CI, 2% to 38%) (6). The effect of aspirin on stroke in these trials was less consistent than that of warfarin (6, 19). When analysis was restricted to disabling strokes, aspirin use was associated with a smaller relative risk reduction (13% [CI, 19% to 36%]) (6). Aspirin may be more efficacious for reducing noncardioembolic strokes than cardioembolic ischemic strokes in patients with atrial fibrillation (20), but cardioembolic strokes are, on average, more disabling than noncardioembolic strokes in atrial fibrillation (21). Noncardioembolic strokes make up a substantial portion of strokes in relatively low-risk patients with atrial fibrillation. The greater the risk for disabling cardioembolic stroke in patients with atrial fibrillation, the less protection aspirin affords (21). Adjusted-dose warfarin is clearly more efficacious than aspirin for prevention of stroke in patients with atrial fibrillation, as suggested by indirect comparisons and by a 36% relative risk reduction (CI, 14% to 52%) seen in meta-analysis of five randomized trials (6). Because of differences in the proportions of cardioembolic and noncardioembolic events, this overall estimate may obscure important differences in relative risk reduction between patients with atrial fibrillation who have high risk for stroke and those who have low risk for stroke (21). Randomized trials involving high-risk patients with atrial fibrillation (stroke rate>6% per year) show large relative risk reductions with adjusted-dose warfarin relative to aspirin (13, 22), whereas the relative risk reductions are consistently smaller in trials involving patients with atrial fibrillation who have lower stroke rates (23-25). Thus, warfarin may be most beneficial for patients with atrial fibrillation who are at higher intrinsic risk for thromboembolism and have a higher proportion of disabling cardioembolic strokes; this agent offers only modest reductions over aspirin in both the relative risk and absolute rates of stroke in patients with atrial fibrillation who are at low risk. Combining low-dose warfarin (INR<1.5) with aspirin adds little additional protection against stroke compared with aspirin alone in patients with atrial fibrillation (13, 23). Adding warfarin therapy to aspirin therapy at higher anticoagulation intensities may accentuate intracranial hemorrhage in elderly patients with atrial fibrillation (26). For patients with atrial fibrillation who sustain cardioembolic events while receiving low-intensity anticoagulation (INR<2.5), we currently favor increasing the anticoagulation intensity up to a maximum target INR of 3.0 to 3.5 rather than routinely adding antiplatelet agents. The value of antiplatelet agents other than aspirin for prevention of stroke in atrial fibrillation remains to be determined (6). Stroke Risk Stratification Most patients with atrial fibrillation never experience a clinical stroke. The stroke rate varies more than 20-fold, from 0.5% per year (27, 28) for young patients without organic heart disease (lone atrial fibrillation) to 12% per year for patients with atrial fibrillation who have had stroke (13, 22, 29). Hence, identification of risk factors for stroke in nonvalvular atrial fibrillation is important because it allows individualized antithrombotic prophylaxis to be given according to stroke risk. Numerous studies have examined risk factors for stroke in atrial fibrillation, and multivariate analyses reveal several consistent, independent predictors of ischemic stroke (Table 2) (17, 28-42). Table 2. Independent Predictors of Ischemic Stroke in Nonvalvular Atrial Fibrillation Mechanisms linking these risk factors to ischemic stroke in atrial fibrillation are incompletely defined. The strong association between hypertension and stroke in atrial fibrillation is primarily mediated by embolism originating as thrombus in the atrial appendage (44). Hypertension in patients with atrial fibrillation is associated with reduced atrial appendage flow velocity, spontaneous echocontrast in the left atrium, and thrombus formation (44-46). Whether sustained control of systemic hypertension reduces the risk for cardioembolic stroke in patients with atrial fibrillation is a vital question because the ventricular abnormalities associated with hypertension in elderly persons are often multifactorial and difficult to reverse (47, 48). Hypertension also increases the risk for noncardioembolic stroke in atrial fibrillation (20, 29), and this type of stroke may be particularly amenable to prophylaxis with aspirin (19, 20, 49). Advancing age increases risk for stroke in atrial fibrillation for many reasons. Aging in patients with atrial fibrillation is associated with left atrial enlargement, reduced atrial appendage flow velocity, and spontaneous echocontrast, each of which predisposes patients to left atrial thrombus formation (45, 46, 50). In addit


PROBLEM TO BE SOLVED: To provide a method for producing high purity diborane having a low higher-order borane content and useful as a dopant and a BPSG (boron phosphor silicate glass) insulating film-forming material in semiconductor manufacturing and solar cell manufacturing, and as a rocket propellant and the like in an easy and inexpensive way in good yield. SOLUTION: The method for producing diborane includes reacting a sodium borohydride with a trihalogenated boron in an atmosphere of an inert gas having hydrogen concentration of 0.01-50 vol.% in the presence of a solvent. Ultrahigh purity diborane required in semiconductor use and the like can be produced industrially efficiently. COPYRIGHT: (C)2011,JPO&INPIT


A polyamide resin composition for a band cable is provided to ensure long-term heat resistance and flexibility comparable to conventional resin compositions even without additional processes. A polyamide resin composition for a band cable comprises (1) 100 parts by weight of a polyamide resin, (2) 0.2-0.8 parts by weight of a phosphorus-based compound represented by the formula 1, (3) 0.2-0.8 parts by weight of a fluorine-based compound represented by the formula 2: (-CF2-CF2)n; (4) 4-9 parts by weight of a sulfonamide-based plasticizer and (5) 8-15 parts by weight of an impact resistant containing a maleic anhydride-grafted ethylene-propylene-diene terpolymer. In the formulae 1 and 2, Ar1 and Ar2 are a substituted or unsubstituted aryl group having 6-7 carbon atoms, in which the aryl substituent is selected from hydrogen and a C1-C6 alkyl group, R1 and R2 is hydrogen or a C1-C6 alkyl group and n is an integer of 2-100.


In this study, we examine the role of nuclear data in Instrumental Neutron Activation Analysis (INAA) particularly as it affects determination of reactor flux parameters and application of comparator methods. The work reviewed the available sources of nuclear data, the variations that exist from one source to the other and the effects of such variations on INAA. Measurement of Neutron flux parameters in inner and outer irradiation channel of a miniature neutron source reactor was carried out using two independent nuclear data sources to investigate the effects of inconsistency of nuclear data on the precision of analytical result. The result obtained shows a slight variation of flux parameters with nuclear data source. It was also observed that modification of the earlier compiled basic nuclear data lead to inconsistencies in the secondary data that applies it.


Ion implantation is used to investigate the spectroscopic properties of Mg, Be, and C acceptors in GaN. Activation of these species is studied using low temperature photoluminescence (PL). Low dose implants into high quality undoped hydride vapor phase epitaxial (HVPE) material are used in conjunction with high temperature (1300 C) rapid thermal anneals to obtain high quality spectra. Dramatic, dose-dependent evidence of Mg acceptor activation is observed without any co-implants, including a strong, sharp neutral Mg acceptor-bound exciton and strong donor-acceptor pair peaks. Variable temperature measurements reveal a band-to-acceptor transition, whose energy yields an optical binding energy of 224 meV. Be and C implants yield only slight evidence of shallow acceptor-related features and produce dose-correlated 2.2 eV PL, attributed to residual implantation damage. Their poor optical activation is tentatively attributed to insufficient vacancy production by these lighter ions. Clear evidence is obtained for donor-Zn acceptor pair and acceptor-bound exciton peaks in Zn-doped HVPE material.


The emergence of a "second wave" of developing-country multinational enterprises (MNEs) in a variety of industries is one of the characterizing features of globalization. These new MNEs did not delay their internationalisation until they were large, as did most of their predecessors, and often become global as a result of direct firm-to-firm contracting. Many grow large as they internationalise conversely, they internationalise in order to grow large. This is a striking pattern which, if confirmed, indicates that enterprises from developing countries have pursued distinctive approaches to internationalisation. It is a further interesting hypothesis to investigate to what extent such firms, born as suppliers of established incumbents, have leveraged on their "latecomer" status to accelerate their internationalisation. This paper documents how emerging MNEs may follow quite different patterns to reach, or at least approach, global competitiveness. In particular, it investigates how three latecomer MNEs pursued global growth through accelerated internationalisation combined with strategic and organizational innovation. Haier (China), Mabe (Mexico) and Arcelik (Turkey) emerged as Dragon Multinationals in the large home appliances (so-called "white goods") industry. This is a producer-driven global value chain, characterized by mature technology and rapid delocalization to developing countries, where not only input costs are lower, but demand growth rates are higher - giving a decided latecomer advantage to these MNEs. Haier, Mabe and Arcelik leveraged their strategic partnership with established MNEs to upgrade their operations, evolving from the production of simple goods, into new product lines developed through their own design, branding and marketing capabilities. The recipe of their success has been the ability to treat global competition as an opportunity to build capabilities, move into more profitable industry segments, and adopt strategies that turn latecomer status into a source of competitive advantage. At the same time, their experiences show that there are many strategies and trajectories for going global.


For years teeth of tetraodontoid fishes generally have been considered coalescent even though "coalescence," which also is found in fishes of other families, has never been well defined. This paper deals with some aspects of coalescence of the teeth in tetraodontoids and attempts to define this condition. The sites of osteodentinogenesis and the mechanisms by which hard tissues are formed, reabsorbed, and abraded during feeding were analyzed from semiserial decalcified sections and from ground sections, as well as from autoradiographs of the premaxilla and dentary bones of Sphoeroides greeleyi. The observations reported here, taken together with other data we have obtained on members of the Tetraodontoidei, permit clear definitions of "tooth" and "supporting bone," and consequently the structural meaning of coalescence. From these data we hypothesize how coalesced masticatory structures may have evolved in this group.


Inspired by these properties of ionic liquids and the application range (range of bilogical application of) of biological selenium compounds we planned in this work the synthesis of a new series of ionic liquids containing selenium with new potential biological activitys (Figure 1). Besides, in our strategy, the diselenides designed should contain heteroatom (N or O) in the favorable position to chelate with Se atom, as well as good solubility in water.


This study was carried out with an objective to investigate the antibacterial and antifungal potential of bark of Delonix elata . Antibacterial activity of various fractions obtained from methanolic extract (PE, DM , EA, MR) of bark were carried out against three Gram positive bac teria – Staphylococcus aureus , Staphylococcus albus, Enterococus faceialis and three Gram negative bacteria Escheric hia coli , Pseudomonas aeruginosa , Klebesiela. The antifungal activity of the fractions was evaluated on two common pathogenic fungi Candida albicans and Cryptcocus neoframens . The testing was done by the disc diffusion method. Zones of inhibition of fract ions were compared with that of standard Amikacin for antibacterial activity and Ketoconazole for antifungal activity. The EA and MR fractions showed significant antibacterial activity but did not exhibit anti - fungal activities comparable with that of stan dard against the organisms tested.


The Raman hight-scattering spectra have been determined for GaAs single crystals implanted with 140-keV Si + ions in doses of 10 13 − 5 × 10 14 cm −2 . The spectra were recorded before and after thermal annealing. The changes in the parameters of the LO component of the spectra of the implanted samples are interpreted on the basis of a model of spatial correlation of phonons. The implanted layer is shown to be a hetero-phase system containing both amorphous and microcrystalline fractions with ordered regions of 50-100 A size. Scattering by coupled phonon-plasmon modes observed in the implanted and annealed samples demonstrates that the crystal structure is restored and the impurity is electrically activated by annealing


Foreign language anxiety (FLA) has been identified as one of the major obstacles to acquisition and fluent production of foreign languages (Dewaele, Petrides, & Furham, 2008; Williams & Andrade, 2008). A lot of research has been conducted on the topic of FLA (e.g., Horwitz, Horwitz, & Cope, 1986) and students who study abroad (e.g., Davidson, 2010; Kinginger, 2008), but there have been very few studies that focus on the relationship between studying abroad and affective factors such as language learning anxiety (e.g., Allen & Herron, 2003; Lee, 2018; Thompson & Lee, 2014). This study analyses the profiles of study abroad learners of Arabic as a foreign language (AFL) in Morocco. A total of 146 American students answered the Foreign Language Classroom Anxiety Scale (FLCAS; Horwitz et al, 1986) and completed a background questionnaire to collect information regarding their amount of experience abroad. Findings showed that participants experienced an average level of FLA. The main factors underlying FLA were Arabic class performance anxiety and negative feelings towards Arabic. Suggestions about the best strategies to reduce anxiety are offered.


As APA policy, the Model Act for State Licensure of Psychologists serves as a prototype for drafting state legislation regulating the practice of psychology. State legislatures are encouraged to use the language of this document and the policies that it espouses as the model for their own state licensure laws. Inevitably each state law will reflect compromises and changes particular to that state, but the APA Model Act is meant to serve as a guide for those involved in the drafting process. State licensing boards must develop their own rules and regulations to supplement the legislation proposed here. This document also serves to educate legislatures about psychology training and practice and serves to synthesize APA policies that bear on the education, training, and practice of professional psychology. This is the fifth set of guidelines for state legislation regulating the practice of psychology that has been developed by the American Psychological Association (APA). The first model for such regulation was developed and adopted as APA policy in 1955 (APA, 1955). The 1955 guidelines stood for 12 years, during which the number of states enacting licensure legislation grew from 9 to 32. In 1967, the APA Committee on State Legislation (COSL) prepared the first revision of the guidelines. That revision was more comprehensive, provided more detailed guidance, and covered more issues relating to regulation of the practice of psychology while reaffirming the basic concept found in the 1955 model (APA, 1967). By 1977, all states and the District of Columbia had enacted licensure legislation. APA's Council of Representatives then determined that the model approved in 1967 was outdated and directed COSL to undertake a revision. However, in January 1979, the Council of Representatives failed to approve the revised model guidelines, leaving the 1967 guidelines to remain as APA policy. In 1984, the Council of Representatives directed the Board of Professional Affairs (BPA) to develop another revision of the existing 1967 model for the Council's consideration. BPA, in turn, directed its Committee on Professional Practice (COPP) to prepare it. This document was approved by the Council of Representatives in February 1987. In 2006, at the recommendation of the Board of Professional Affairs and the Committee for the Advancement of Professional Practice, the APA Board of Directors and Council of Representatives funded a Task Force to undertake the revision of the 1987 model act. The existing model act did not reflect the developments in professional practice that had occurred over the preceding 20 years. Specific developments included some psychologists obtaining prescriptive authority, changes in the provision of industrial-organizational and consulting psychology that could make it desirable for those psychologists to be licensed, and changes in the recommended sequence of education and training for psychologists. The Task Force undertook this effort beginning with a comprehensive review of the 1987 document as well as relevant APA policies and other documents. Draft revisions were circulated for review, and a 90-day public comment period ensued. Changes were made to the document based on commentary received. A second public comment period ensued, and another review by governance groups followed by additional changes to the document occurred prior to the document's being approved by Council in February 2010. Each section of the proposed Model Act is introduced by commentary, the purpose of which is to explain the rationale for the proposed section that follows. To differentiate between the commentary and the proposed statutory language, the latter is italicized.


Purpose
Integrated reporting (IR) promotes the disclosure of future-oriented information to enable financial stakeholders to make better-informed decisions. However, the downside to this type of disclosure is the risk to management of disclosing such future-oriented information. This paper aims to explore how IR preparers manage the risk of disclosing future-oriented information in companies' integrated reports.

Design/methodology/approach
This study represents an exploratory interpretative thematic analysis of 33 semi-structured interviews with managers involved in IR in eight Sri Lankan companies representing various industries. The thematic analysis is informed by the research literature and prior studies on IR.

Findings
This paper provides evidence of various strategies to manage the risk associated with the disclosure of future-oriented information in integrated reports. These strategies include making non-specific predictions; increasing the accuracy of the predictions; linking performance management to disclosed targets, thus ensuring individual responsibility for target achievement; disclosing ex post explanations for not achieving previously disclosed targets; and linking disclosed targets to the company's risk management procedures. However, these strategies can cause managers to provide conservative future-oriented information, rather than "best estimate" future-oriented information.

Practical implications
The study describes the strategies that managers use to mitigate the risks involved in disclosing future-oriented information. These strategies can provide support or raise concerns, for managers in deciding how to deal with such risks. Regulators tasked with investor protection, as well as stock exchanges interested in the transparency and accountability of listed companies' activities should be aware of these strategies. Furthermore, the International Integrated Reporting Council (IIRC) should be interested in the implications of this study because some of the identified strategies could undermine the usefulness of integrated reports to stakeholders. This is a significant concern given that the IIRC envisages integrated reporting and thinking as vehicles that could align capital allocation and corporate behaviour with wider sustainable development goals.

Social implications
The trend of future-oriented information moving from being used only in organisations' internal management systems to being externally reported in integrated reports has implications for stakeholder groups interested in the reported targets. This study reveals management strategies that could affect future-oriented information reliability and reduce their usefulness for users of integrated reports.

Originality/value
This study provides unique insights into the emerging area of how managers deal with the risks involved in disclosing future-oriented IR information.


Face recognition being the foremost important biometric attribute it still faces many challenges, like variation in images, illumination variation etc. Once such variations are present in each pose and illumination, all the algorithms are greatly stricken by these variations and their performance gets degraded. The method to identify faces in given video sequence is presented in this paper. Identification of faces in the given frames can be done using viola Jones classification model. Frames are separated and categorized in two sections Good frames and Bad frames. Good frames mean the frames which containing face or faces, and Bad frames means frames, which does not contain face. Face detection is the first stage towards face recognition. This is called preprocessing for face recognition method. The frames obtained by this method can be put for further processing as far as face recognition is concerned.


The growing of CO2 emission is a very serious threat to the global ecological environment.How to control the carbon emission is a great concern in the world.Economic structure reshaping and development in technology are playing important role in the process.Researches also show that urban spatial structure has a lock in effect on CO2 emission and sustainable urban development,most cities in China are undertaking spatial restructuring now,how to plan a more sustainable spatial structure is worthy of study.In this paper,based on the development of low carban emissions,we analyzes the content from the space status of Changsha-zhuzhou-xiangtan urban agglomeration,Combined with the influence of low carbon development to the adjustment of regional industry space,rural and urban space,traffic space,ecological space for,put forward the low carbon space structure of C-Z-T urban agglomeration,in order to adapt to the requirement of low carbon sustainable development.


Essential oils obtained by hydrodistillation of seeds, pericarps, leaves and rhizomes of Aframomum dalzielii, A letestuianum and A. pruinosum grown in Cameroon were analyzed by GC-FID and GC-MS. The seed oils of the three species were characterized by a high content of (E)-(R)-nerolidol (>88.0 %), which was fully characterized by NMR spectroscopy and chiral GC analysis. The main constituents of the pericarp and rhizome oils were monoterpene hydrocarbons, mainly β-pinene (0.8%–22.9%) and sabinene (29.0%–42.3%), along with 1,8-cineole (4.5%–23.7%); leaf oils were characterized by sesquiterpenes, namely (E)-β-caryophyllene (18.4%–82.4%) and caryophyllene oxide (4.5%–23.7%). The antibacterial activities of these essential oils and of nine pure compounds (sabinene, β-pinene, 1,8-cineole, linalool, racemic (E)-nerolidol, (E)-(R)-nerolidol, (E)-β-caryophyllene, α-humulene and caryophyllene oxide) were assessed against Micrococcus luteus and Escherichia coli. The strongest activities were observed against E. coli. The seed essential oils and their major component, (E)-(R)-nerolidol, exhibited the lowest MIC values (0.19-0.39 μL/mL), justifying their traditional use and their potential application as natural food preservatives.


The tuned liquid column damper (TLCD) having a uniform cross-sectional tube of U-shaped, occupied with liquid is used as a vibrational response mitigation device. The tuned liquid column ball damper (TLCBD) is a modified TLCD, where, an immovable orifice, positioned at the middle part of the horizontal portion, is replaced by a metal ball. Different studies on the unconstrained optimization performance of TLCBD subjected to the stochastic earthquake have been performed where limitations on the maximum amplitude of liquid present in the vertical portion of the tube were not imposed. In the case of the high magnitude of earthquake and space constraint, the excessive liquid movement might get generated in the vertical portion of the tube which can create challenging circumstances. This can be taken care of by restricting the liquid movement up to a certain limit. The present investigation considers the optimum performance of the structure with TLCBD for mitigating the vibrational response with limited liquid movement in the vertical portion of the tube. A numerical study has been carried out to demonstrate the difference between constrained and unconstrained optimization of structure-TLCBD system. Numerical results show the influence of constraining cases on optimum parameters and performance behavior of the structure-TLCBD system.


Series Preface. Acknowledgements. Introduction. Part I: Recruiting and Selecting a Diverse Workforce:. 1. EEO Law and Managing Diversity: Elaine K. Yakura. 2. The Implications of a Diverse Labor Market on Human Resource Planning: Richard D. Arvey, Ross E. Azevedo, Daniel Ostgaard and Sumita Raghuram. 3. Diversity Considerations in Staffing Decision Making: Robert L. Heneman, Nancy E. Waldeck and M. Cushnie. Part II: Developing and Motivating a Changing Workforce:. 4. Mentoring in a Context of Diversity and Turbulence: Kathy E. Kram and Douglas T. Hall. 5. Performance Appraisal and Demographic Diversity: Issues Regarding Appraisals, Appraisers, and Appraising: Chao C. Chen and Nancy DiTomaso. 6. The Role of Training in a Changing Workforce: New Perspectives and Approaches: J. Kevin Ford and Sandra Fisher. 7. Compensation and Diversity: New Pay for a New Workforce?: Alison E. Barber and Christina L. Daly. Part III: Innovations in Diversity Management:. 8. Human Resource Strategies to Support Diversity in Work and Personal Lifestyles: Sharon A. Lobel and Ellen Ernst Kossek. 9. Unions, Collective Bargaining and the Diversity Paradox: John T. Delaney and M. Catherine Lundy. 10. Workplace Health and Safety: Implications for Diversity: Karen A. Brown. 11. Managing Disability--Based Diversity: Karen Roberts. Part IV: Linking Diversity to Organizational Strategy:. 12. Managing Diversity within Multinational Firms for Competitive Advantage: Gary W. Florkowski. 13. Diversity: A Strategic Issue: Parshotam Dass and Barbara Parker. 14. Capitalizing on the Benefits of Diversity through Work Teams: Donna Thompson and Laura E. Gooler. Part V: Managing Diversity and Organizational Development: Original Cases and Lessons from the Field:. 15. Personal Reflections on the Diversity--Management--Organizational Development Marriage: Roosevelt Thomas. 16. To Do or Not to Do: Initiating Diversity Programs: Everette J. Freeman. 17. Managing Diversity as a Vehicle for Culture Change: Ellen Ernst Kossek. 18. Functional Diversity at Work: A Client Driven Case for Managing Diversity: Toni A. Gregory and Ronald P. Lewis. 19. Crossing Borders: Bernardo M. Ferdman and Placida I. Gallegos. 20. Adapting Human Resource Systems to Manage Global Diversity: Ellen Ernst Kossek. About the Contributors. Index.


Today, cyber physical systems (CPS) are becoming popular in power networks, healthcare devices, transportation networks, industrial process and infrastructures. As cyber physical systems are used more and more extensively and thoroughly, security of cyber physical systems has become the utmost important concern in system design, implementation and research. Many kinds of attacks arise (e.g. the Stuxnet worm), causing heavy losses and serious potential security risks. For the past few years, researchers are focusing their researches on different aspects of security of cyber physical systems. In this paper, we propose a security framework assuring the security of cyber physical systems and analyze main universities and institutes studying CPS security and their relations in three levels: CPS security objectives, CPS security approaches and security in specific CPS applications. Finally, a conclusion of this article is given.


Color Atlas of Pediatric Rheumatology BM Ansell, S Rudge, and JG Schaller. 208 pages. Baltimore: Mosby-Wolfe; 1995. $49.95. ISBN 0-00815-102210. Order phone 800-426-4545. Excellent color illustrations, including many close-up views of joints and skin and nail lesions. The illustrations of histologic sections are of lower quality than the other views. Typical roentgenographs. All illustrations have descriptive legends; otherwise, the text is limited to tabular summaries of the diseases illustrated in the following pages.


OBJECTIVE
Vilazodone was recently approved by the US Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD). The purpose of this review is to summarize the FDA's approach to its review of the clinical pharmacology and the clinical efficacy and safety data for this new drug application, important issues in its decision-making, and its conclusions.

DATA SOURCES
The data sources for this review were the original raw data sets for all clinical trials included in the development program for vilazodone, as well as the sponsor's original analyses of these data.

STUDY SELECTION
Data were available from 24 human trials involving vilazodone, and included a total of 2,898 human subjects exposed to 1 or more doses of this drug.

DATA EXTRACTION
The FDA had access to original raw data sets for these trials.

RESULTS
Vilazodone is effective in treating MDD at a dose of 40 mg/d, but it needs to be incrementally adjusted to this dose to minimize gastrointestinal symptoms. It needs to be taken with food to ensure adequate plasma concentrations. Vilazodone's profile of adverse events is similar to that seen with selective serotonin reuptake inhibitors. No dose adjustment is needed based on age, gender, or renal or hepatic impairment. It is recommended that the vilazodone dose be reduced to 20 mg when it is taken with strong cytochrome P450 (CYP) 3A4 inhibitors, eg, ketoconazole. Vilazodone is not expected to have important effects on the clearance of other drugs that are cytochrome P450 substrates.

CONCLUSIONS
Vilazodone is a new treatment for MDD, but it is unknown whether it has any advantages compared to other drugs in the antidepressant class.


Abstract Meiosis in female oocytes lack centrosomes, the major microtubule-organizing center, which may make them especially vulnerable to aneuploidy. In the acentrosomal oocytes of Drosophila, meiotic spindle assembly depends on the chromosomal passenger complex (CPC). Aurora B is the catalytic component of the CPC while the remaining subunits regulate its localization. Using an inhibitor of Aurora B activity, Binucleine 2, we found that continuous Aurora B activity is required to maintain the oocyte spindle during meiosis I. Furthermore, the necessity of a kinase for spindle regulation suggests that spindle dynamics is regulated by phosphatases. Our result have shown that the protein complex Protein Phosphatase 2A (PP2A) opposes CPC activity, probably by dephosphorylating spindle associated proteins such as the Kinesins. PP2A exists in two varieties, B55 and B56. While both antagonize Aurora B, they typically exhibit different localization and function. B55 has only minor roles in meiosis I spindle function. The B56 subunit is encoded by two partially redundant paralogs in the Drosophila genome, wdb and wrd. Knocking down both B56 subunits showed they are critical for multiple functions during meiosis I, including maintaining sister centromere and arm cohesion, end-on microtubule attachments, and the metaphase I arrest in oocytes. We found that WDB recruitment to the centromeres depends on BubR1, MEI-S332, and kinetochore protein SPC105R. However, only SPC105R is required for cohesion maintenance during meiosis I. We propose that SPC105R promotes cohesion maintenance by recruiting two proteins that further recruit PP2A, MEI-S332, and the Soronin homolog Dalmatian.


A nicked reaction: The title reaction of terminal alkynes with non-activated secondary alkyl iodides and bromides was accomplished for the first time. This reaction provides a new and practical approach for the synthesis of substituted alkynes (see scheme; cod=cyclo-1,5-octadiene).


On the basis of making a simple description for the characteristics and devolopment of EC,the paper analyses the functions of material flow based on EC and advances that logistics enterprises should accomplish their reform by two steps in orde to cater to the needs of development of EC.


Study of semileptonic decays of neutral kaons allows to perform a test of discrete symmetries, as well as basic principles of the Standard Model. In this paper a general review on dependency between charge asymmetry constructed for semileptonic decays of short- and long-lived kaons and CPT symmetry is given. The current status of determination of charge asymmetry for short-lived kaon, obtained by reconstruction of about 105 KS → πeν decays collected at DAΦNE with the KLOE detector is also reviewed.


Thank you for reading handbook of scripts and alphabets. As you may know, people have look hundreds times for their favorite novels like this handbook of scripts and alphabets, but end up in harmful downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they are facing with some harmful bugs inside their computer. handbook of scripts and alphabets is available in our book collection an online access to it is set as public so you can get it instantly. Our book servers saves in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Merely said, the handbook of scripts and alphabets is universally compatible with any devices to read.


We have investigated the electronic and optical properties of TiB monoboride using the density functional theory within the generalized gradient approximation (GGA) for exchange and correlation. Ground state properties such as lattice constant, cell volume and bulk modulus are calculated. The optimized lattice constant is in good agreement with the experimental and available theoretical results. The band structure and density of states (DOS) have been calculated along high symmetry directions in the first brillouin zone. The calculated band structure predicts that the TiB compound is metal. Further the features of optical properties such as reflectivity, absorption, refractive index, dielectric function, conductivity, loss function are obtained and discussed. All these calculations have been carried out using CASTEP computer code. This is the first theoretical prediction of these properties.


This template will assist you in creating a data management plan for arts-based research (ABR). It is intended for researchers and artists who use artistic processes as research methods (i.e., arts-based methods). ABR is used across disciplines and encompasses diverse understandings of the arts, research, and how they intersect. In this template, ABR is an umbrella term for all the ways the arts are adapted to answer research questions, including those described as arts research, artistic research, and research-creation. You can use this template on its own, or in combination with others on the DMP Assistant when using arts-based methods with other methodological approaches.


Two separate factorial experiments were conducted to study the effects of explant sources, plant growth regulators, sucrose concentrations, and light conditions on in vitro cormlet formation of freesia (Freesia ×hybrida Bailey 'Argenta'). Interestingly, it was observed that the pupae had lower contamination levels compared to mother corms. Using 40% sodium hypochlorite solution for 40 min, contamination levels of pupae and mother corms reduced to 19.80 and 46.40%, respectively. Moreover, pupae showed the highest regeneration frequency. In the first experiment, 6.67 cormlets were directly produced per pupa (cold storage-produced corm) on Murashige and Skoog (MS) medium supplemented with 6 mg L-1 1-naphthaleneacetic acid (NAA), 1 mg L-1 6-benzylaminopurine (BA), and 60 g L-1 sucrose, when cultures were stored in the dark. In the second experiment, on average, 5.67 shoots were proliferated per pupa explant in the presence of 4 mg L-1 BA and 2 mg L-1 Kinetin (Kin). Subculturing these shoots on MS medium containing 3 mg L-1 BA and 0.5 mg L-1 NAA led to production of 3.67 cormlets per shoot. Finally, in vitro derived cormlets showed the highest percentage of rooting (77.80%), root number (8.33), and root length (2.13 cm) on MS medium containing 1 mg L-1 indole-3-butyric acid (IBA).


This study to test talent management on employee performance totest knolege management on rmployee performance. This study was conducted at TVRI, west Sumatera Province. This type of research was quantitative. The sampling method used a total sampling of 57 saturated samples. The sources of this data are primary data and secondary data. The data analysis techniques used are validity, reliability, descriptive analysis, normality  test, multicolinearity test,  heteroscedasticit y test, multiple regression analysis, and t test. The results show  that talent management has a positive and significant effect on employee performance and knowledge management has a positive and  positive and significand effect on employee performance, it can be concluded that talent management is accepted and knowledge management is accepted


To investigate the tribological interaction and wear mechanisms of polytetrafluoroethylene-lined radial lip oil seals in service, a sleeve, seal and lubricant sample taken off a rotating rig are studied. The test was terminated at 72 h, after severe leakage in the final 15 h of the test. All three components are studied using a coherence scanning interferometer and environmental scanning electron microscopy to investigate wear after testing. Results show a wear band on the aerospace grade case-hardened sleeve, appearing as a 'polished in' area by the seal. A study of the filler content of the polytetrafluoroethylene coating uncover glass fibres, calcium carbonate, carbon and graphite layers present, assumed responsible for the wear to the sleeve. The polytetrafluoroethylene coating is a 300 μm coating, distinct from the bulk elastomer. This finding is confirmed after observing this layer on both, the tested and new seal lip. Wear of the seal lip is measured and facilitated by comparison to the identical new seal. Lastly, debris from the seal and sleeve wear are found in the lubricant sample.


This paper discussed the possibility of modeling Microgrid based on IEC 61850. IEC 61850 standard hit a great success in substation automation system with its good interoperability and three-level hierarchy structure containing substation level, bay level and process level. In addition, Microgrid took similar three-level control, which was therefore the application foundation. This paper tried a new application of IEC 61850 for Microgrid by modeling based on the unique characteristics of this standard, and finally built the Microgrid model.


A method of obtaining some of the out‐of‐plane force constants in conjugated hydrocarbons from bond orders and of borrowing the other kinds of these constants from similar molecules is described. The method includes the assumptions that the force constant of torsion around the CC bond is proportional to the product of the π bond order and the overlap integral of the carbon 2pπ atomic orbital and that the interaction constant between wagging motion of a CH group and a torsion around a CC bond to which the CH group is attached is proportional to the diagonal constant of the torsion. The validity of these assumptions is discussed. As an application of the method the nonplanar frequencies of trans‐butadiene are calculated and compared with experimental values. The results are found to be encouraging.


A small megaphone was tested for use in direct voice communication at high voice levels against backgrounds of noise. The voice transmission characteristics of the megaphone were measured. Intelligibility scores were determined for ten talkers, speaking with and without the megaphone, over a range of field voice levels of 70 to 100 db SPL (at 1 meter). A white noise and a low‐frequency noise background were employed. Nearly the entire over‐all acoustical gain produced by the megaphone was realized in improved intelligibility above both noise spectra. The acoustical gain of the megaphone permitted a lower voice level, and, hence, delayed the deterioration in intelligibility associated with distortions due to shouting. Frequency shifts in the voice spectrum were measured over a range of vocal efforts from conversational maximum shout. Control tests demonstrate that the voice‐frequency shifts associated with shouting are not the primary factor in the deterioration of intelligibility; the frequency shifts appear to be only symptomatic of serious vocal distortions in shouting.


MOLECULAR MECHANISMS INVOVLED IN CALCINEURIN INHIBITOR NEPHROTOXICITY IN KIDNEY ALLOGRAFT By Huong Le Diem Nguyen, M.S. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Physiology at Virginia Commonwealth University. Virginia Commonwealth University, 2011. Major Director: Valeria Mas, Ph.D. Associate Professor, Department of Surgery and Pathology Director of Molecular Transplant Research Laboratory, Division of Transplant Calcineurin inhibitors (CNI), cyclosporin A and tacrolimus, are potent immunosuppressive agents but induce toxicity causing damages and graft dysfunction in kidney transplant recipients. They also have been suggested to contribute to late-term loss of graft, which is depicted by interstitial fibrosis and tubular atrophy (IF/TA). Even with emerging insights on mechanism of CNI nephrotoxicity, prevention and treatment of this toxicity remain a major clinical challenge due to its low dose-toxicity correlation, a difficulty in establishing a differential diagnosis, and varying individual susceptibility. We hypothesize that CNI nephrotoxicity follows distinct disease pathways and is characterized by significant gene signatures that differentiate it from other conditions. Moreover, we postulate that CNI-induced toxicity profiles contribute to the IF/TA signatures. Microarray analysis and gene annotation were done on the study database included of tissues diagnosed with CNI nephrotoxicity (n = 9), interstitial fibrosis/tubular


This article deals with the applications of fault tree analysis in NC machine tool failure diagnosis with an example of establishing fault tree for a power-supply system of a processing center. Suggestions are given as to the maintenance of facilities so as to improve its utilization rate.


The authors investigated the sources of meaning for active seniors. Results indicated that seniors who were most active were relatively high in a wide range of sources of meaning as well as in life satisfaction in general. The importance of meaning and purpose in relation to counseling with older adults is discussed. ********** The United States and other nations are witnessing a rapid rise in the numbers of retired, older adults (i.e., those who are 65 years old or older). This global aging phenomenon is predicted to be a demographic transformation with "wrenching economic and social costs" (Peterson, 1999, p. 4). In considering the needs of older adults, developmental psychologists, gerontologists, counselors, and professionals who focus on long-term care are giving more attention to the role and development of personal meaning in late adulthood. The need for such perspectives is a major theme of the present article. The greatest demands in the growing population of older adults are expected to come from the even greater proportionate growth in older individuals who describe themselves as thriving and healthy. Two thirds of adults over 65 years old describe themselves as having good or excellent health, and that percentage is expected to rise (Rubinstein, 2002b; Verbrugge, 1989). Retirees at age 62 can expect to experience another 20-30 years of challenges and transitions in which purpose and meaning take on greater importance. There are many advantages for counselors to adopt teleological approaches that emphasize meaning and purpose in the planning, treatment, and care of older persons. A focus on meaning and purpose provides a positive, optimistic perspective that is counter to disempowering views of aging based on losses and deficits. "Bleak and pessimistic" images of growing old as a "sad and negative occurrence" have typically prevailed (Sperry, 1992, p. 387). Strategies to maintain purpose will be especially important when the transitions of old age center around losses of role or function in life, such as the loss of the parenting role, widowhood, chronic physical conditions, and retirement (Solis & Brink, 1992). Gerontologists and developmental psychologists have long thought that personal meaning is a key aspect of successful aging (Birren, 1964; Butler, 1973; Erikson, 1963). This is especially true because old age is a time when one's sources of meaning are at greatest risk by virtue of the losses of personal relationships as well as the loss of career and community roles. In fact, professionals in treatment and caregiving arenas are paying more attention to the maintenance of purpose and meaning in old age. Health fields such as nursing and health education, through their focus on wellness, have also grasped the importance of perspectives that emphasize the maintenance of personal meaning throughout the life span. Hospice care programs have a primary mission of maintaining meaning in later stages of life. The Eden Alternative approach to long-term care helps individuals in nursing homes to maintain a purposeful life by reducing loneliness, helplessness, and boredom (Thomas, 1996). The successes of the leisure industry aimed at seniors, continuing education programs for the retired, and the efforts of senior centers to provide meaningful activities for individuals who have retired all demonstrate the significance of meaningful pursuits. Prager (1996) has praised calls for more symbolic, philosophical, and heuristic orientations toward ... the aging process ... Though still in an embryonic stage, epistemological, idealist, or humanist models of gerontological inquiry are coming into their own, complementing and supplementing the empiricist models of the natural sciences. (p. 118) Leder's (2002) suggestions for "conscious aging" encourage meaning and purpose in passages through later life. Counselors have a role and a responsibility in assisting individuals in late adulthood to continue to define themselves in terms of having meaningful life goals and a sense of purpose. …


In this paper, we prove a dichotomy theorem for re- mainders in compactications of paratopological groups: every re- mainder of a paratopological group G is either Lindelof and meager or Baire. Furthermore, we give a negative answer to a question posed in (D. Basile and A. Bella, About remainders in compacti- cations of homogeneous spaces, Comment. Math. Univ. Carolin. 50 (2009), no. 4, 607{613). Some questions about remainders in compactications


it has been almost 150 years since the great civil war was fought in the United States and in this bloody civil war which killed more than 600.000 soldiers Abraham Lincoln emerged as a statesman who preserved the Union and abolished slavery. Lincoln's journey from a country lawyer in Illinois to the greatest U.S. presidents has been well documented. However, there is not a lot of literature around his distinctive leadership qualities and how they shaped the future of America. Lincoln was not the primary choice of the Republican Party as a nominee in the Presidential election of 1860. In fact he was the fourth choice. In spite of this, his supporters managed to nominate him as the party's candidate and he won the election. Lincoln's generosity and kind heartedness are legendary. With these traits he changed the hearts of many of his political enemies some of whom eventually helped elect him to the Presidency. His Presidency faced some of the biggest crises the US has ever seen and through his leadership the country was able to stay united in extremely delicate circumstances. He achieved seemingly impossible feats in the four years of his Presidency. This work explores the qualities which made him a great leader and how they can help today's business leaders surmount the massive problems they face.


To the memory of Alejandro Glusman. iii Acknowledgments This thesis would not have been possible without the encouragement, support, and generous guidance of Ward Henson and Yves Raynaud. I also benefitted from extensive and illuminating conversations with my friend Alexander Berenstein. Finally, I received kind support from my wife Kimberly, my parents, and my brothers and friends. iv Preface Historically, the connection between model theory and functional analysis was first made evident by the introduction of Banach space ultraproducts by Bretagnolle, Dacunha-Castelle, and Krivine [6], and of non


This study tested a model of interpersonal communication motives and the construct validity of the Interpersonal Communication Motives Instrument (ICM). Specifically, we hypothesized that ICM would be differentially related to who we talk to, how we talk, and what we talk about. In Study 1, questionnaires were completed by 319 adults who rated their interpersonal communication motives to a target person at one of six relationship levels: stranger, formal friend, co‐worker, close friend, family member, and spouse/lover. Study 2 involved 586 adults who completed questionnaires assessing ICM, likelihood of self‐disclosure, and communicator style. Results indicated that more intimate relationship levels were better seen as fulfilling affection and inclusion motives. Escape and control were related to both the directive and active dimensions of communicator style. Breadth of disclosure was related to pleasure, affection, inclusion, and escape motives; depth of disclosure was related to inclusion, escape, and c...


The permittivities of N,N-dimethylformamide (DMF), water (H2O), and DMF-H2O mixture solution were measured by a resonant cavity perturbation method at 2.45 GHz and 288, 298, and 313 K. The measured results showed a specific phenomenon wherein the imaginary part of the solution′s permittivity was larger than that of each of the components. A theoretical calculation indicates that the reason for this phenomenon is high frequency friction increasing in the DMF and H2O mixture. This implies that a new formula needs to be formulated to include hydrogen bond contributions for the explanation of this specific phenomenon.


Using a novel combined algorithm based on an antenna theory model and the Electromagnetic Transients Program, we study how the induced overvoltage on overhead lines due to a nearby lightning stroke is propagated in a distribution network with power electronic devices. It is shown that the presence of surge protection devices can considerably reduce the induced overvoltage, provided that they are placed properly in the network.


Studies the methods used to ensure that new product development in an industrial and technical environment is market led. Begins with the customer active paradigm of Eric Von Hippel, and then develops a proactive approach to new product development. Reports on a three‐year action programme applied to a UK division of a multinational corporation. Although the study is concentrated on one in‐depth longitudinal example, the authors are confident that the results can be applied more widely.


Neisseria gonorrhoeae does severe harm to human health,and human is the only natural host of Neisseria gonorrhoeae and commonly susceptible to it.Pilus,LOS,IgA1as well as PⅠ,PⅡ,PⅢ,these virulence factors of pathogen and immune escape of Neisseria gonorrhoeae help its escape from attack of the host cell immunity,humoral immune and complement mediated killer immune function.Hence,infected people could not gain solid and specific immunity,and repeated infection occur.With further study of pathogenic and escape mechanism of Neisseria gonorrhoeae,rapid development has been made in the immune escape mechanisms in recent years.


National Early Warning Score (NEWS) has been shown to be the best early warning score to predict in‐hospital mortality but there is limited information on its predictive value in a prehospital setting. The aim of the current study was to investigate the diagnostic accuracy of NEWS in a prehospital setting using large population‐based databases in terms of short‐term mortality.


During the second season of work carried out by the Humboldt University Nubian Expedition (H.U.N.E.) in the area of Kirbekan2 3 , remarkable achievements were made in the field of funerary archaeology (cf. Budka in this volume). A considerable amount of so-called dome graves' and crevice graves, isolated or arranged in groups, was found during the field reconnaissance in 2005 (44 sites with a total of 119 graves). Dome graves have already been identified by other missions working in the Fourth Cataract area (GAME, SARS).4 5As H. Paner has pointed out, this particular type of grave might be a regional tradition since, as of yet, it has only been found sporadically elsewhere.' Although most of the graves were looted in antiquity, pottery has sometimes been found in the surrounding area. These ceramics comprise both Kerma and distinctive Napatan shapes and wares. Some tombs within H.U.N.E.'s concession were selected for excavation, to prove the connection of this material with the date of the structures.6 7


Background:
 Acetyl-LDL and resistin have been proved to play a critical role in inducing VSMC malfunction in the process of atherosclerosis. Ginsenoside Rb1, a major consitituent of Ginseng that has been used for thousands of years, was reported to have powerful vascular-protective effect. Here we aim to explore its protective effect on Acetyl-LDL and resistin induced dysfunction in VSMCs.

 Methods:
 Human coronary artery smooth muscle cells (HCASMC) were used at passage 5 to 8 for experiments. Cells were treated for various time points with or without resistin at 40 ng/mL and Acetyl-LDL in the presence or absence of Rb1. TBHP was also used as a positive control. Cell migration was analyzed using scratch wound assay, and cytosolic ROS (H2DCFDA as a dye probe) was measured by microplate reader and compared among groups.

 Results:
 Resistin time-dependently increased HCASMC migration, which could be significantly attenuated by Rb1 at 20μM. Resistin and Act-LDL increased ROS production in HCASMCs to a similar level, while pretreatment with Rb1 reversed the effects by resistin and acetyl-LDL. In addition, we demonstrated that both resistin and Rb1 had dose-dependent effect on ROS production in HCSMCs and that Rb1 at 40μM pre-treatment significantly reduced resistin (40ng/ml) induced cytosolic ROS in VSMCs.

 Conclusion:
 We demonstrated the protective effect of Rb1 on HCASMC and showed, for the first time, that Rb1 pre-treatment being more effective than co-treatment, suggesting that ginsenoside Rb1 has the potential of protecting against atherosclerosis. More in-dept study is needed.


The article highlights definition, meaning plus the advantages and disadvantages of open access. It shows the development of open access journals in the present era. It gives the brief idea of how open access is helping the user community in getting the information needed by them without much efforts. It also shows that the modern users are slowly opting open source mode for their information needs.


Image Super-resolution (SR) has gained considerable attention in artificial intelligence (AI) research and image-based applications. Recent deep learning-based SR models have demonstrated remarkable accuracy and perceptual quality in the resulting images. However, the computational cost and model parameters are the most challenging limitations in real-world applications. Additionally, designing an efficient and lightweight SR algorithm to improve the perceptual quality of the SR images is a critical issue. According to these considerations, we propose a Multi-FusNet of Cross Channel Network (MFCC) network by modeling a multipath residual network, named multi-RG, with cross-filtering fusion. Additionally, a pixel shuffling fusion technique is used to fuse low-level features into the up-sampled features of the multi-RG. The experimental results show the comparison of the proposed MFCC to the state-of-the-art SR models. The proposed method significantly reduces the number of network parameters (8.4 times compared to RCAN) while preserving the visual quality of the result and achieving the best PSNR value compared to the other state-of-the-art methods.


The identification of non-English-language trials is important to reduce the impact of the foreign language bias, one the main sources of selection bias in meta -analyses. Obviously the identification of clinical trial by medical database such as Medline and Embase is the most optimal decision. Unfortunately only few Russian medical journals are cited in Medline. Moreover it is impossible to identify design and quality of publication when we use Russian national medical database OPAC-R because there are no keyword determinating the type of clinical trial in this database. In this connection only handsearch seems to be the more applicable way to identify randomized control trials or controlled trials in Russian medical journals. BACKGROUND BACKGROUND


Dyslexia and attention-deficit/hyperactivity disorder (ADHD) are 2 of the most prevalent complex neurodevelopmental disorders of childhood, each affecting approximately 5% of the population in the United States. These disorders are also each comorbid with speech sound disorder and language impairment. Understanding the nature of the comorbidity among these disorders could lead to advances in developmental theory, a deeper understanding of the genetic and brain mechanisms that cause disability, a more refined diagnostic classification scheme, and new treatments and interventions for children with these disorders. As part of this special issue of Topics in Language Disorders, this review focuses on the comorbidity between dyslexia and ADHD. It provides a review of the known etiological mechanisms that underlie each disorder. It describes the reconceptualization of these disorders using a multiple deficit model and provides a synopsis of recent studies that illustrate a cohesive approach to investigating the causes of comorbidity. Future directions are discussed in the context of expanding these approaches to the comorbidity among all 4 disorders. Key words: ADHD, attention-deficit/hyperactivity disorder, comorbidity, dyslexia, genetics, reading disability


In the following article Doctor Szakats evaluates the workers' position with regard to the necessity of membership in union as an indispensable prerequisite for obtaining and retaining work. In particular, he analyzes current employer-union practices and legislation in New Zealand, Great Britain and the United States. The author points out that in New Zealand the relevant statutes apply only to registered workers' associations. However, registered union has the advantages of: monopoly position; blanket clauses; and unqualified preference clauses. The author concludes that the so-called abolition of compulsory unionism in New Zealand does not change the position of workers seeking employment since by virtue of the unqualified preference clauses in nearly all awards and industrial agreements, compulsory unionism has de facto remained in force. In Great Britain, as in New Zealand, relevant statutes apply only to registered associations. Although it has been recognized in Great Britain since 1871 that trade unions are voluntary associations, the theory does not always conform with the practice. As result, certain arrangements can inhibit worker's choice of specified trade union and closed shop agreements may lawfully counteract this right of not joining, thereby introducing de facto compulsory unionism. By way of contrast to Great Britain and New Zealand, relevant legislation in the United States extends to and binds all trade unions. The author concludes that although com pulsory unionism imposed by the state generally weakens the labour movement, compulsory unionism imposed by employer-union agreement strengthens the movement.


This study investigates the ultimate load capacity of concrete 1.5 m diameter bored pile based on three methods: field-loading test, field Standard Penetration Test results, and numerical modeling. A comparison of the ultimate load capacities from these methods was made (the measured large-scale field-loading test, the correlated SPT N values applying Novo SPT software and numerical modeling where Plaxis3D software with Mohr-Coulomb model was utilized). The result of the pile field-loading test was more accurate than the other methods and used as a reference for comparison among their results. In general, the value of ultimate load capacity calculated from Novo SPT software and that obtained from numerical analysis were compatible in comparison with field load results.


Devices employing electron beam-electromagnetic wave interaction are classified in accordance with the phase velocity of the wave. Some general principles are stated governing the beam size and position applicable to all types of slow-wave interaction and for various types of fast-wave devices such as the gyrotron, the free-electron laser, and their derivatives. The quality of the electron beam, its energy, and the magnetic field strength required are indicated for each type of interaction. The characteristics of the various devices are compared in the context of achieving high-power operation at millimeter wavelengths. Some recent experimental research achievements in the U.S. and the U.S.S.R. are listed to indicate the current state of the art. Finally, areas that appear fruitful for further work are recommended.


In order to understand and use the Bible intelligently and responsibly, it is helpful to consider its entire history - how it came to be, from its earliest origins and through all the various processes that influenced its development and brought it to its final shape. This chapter examines issues, and illustrates them with examples, of the overlap between composition, redaction, textual transmission, and reception. It gives an evolutionary overview of the history of the production of the biblical texts mainly chronologically, but also with an eye toward the types of growth and motivations of the "scribes" or "handlers" of the text who produced the growth. Author's attempts to view the whole process, from origins and production to reception of the books as established canon, will necessarily require lack of focus on many details. He uses a number of familiar building blocks to illustrate the processes of composition, redaction, transmission, and reception. Keywords: Bible; evolutionary production; reception; redaction; scriptural books; textual transmission


To the Editors: Vergara-Rodrguez et al report on the lack of a pharmacodynamic effect of Atazanavir (ATV) on buprenorphine/ naloxone seen in the Buprenorphine HIV Evaluation and Support (BHIVES) Collaborative. This observational study in clinical care provides a "real-world" examination of this potential interaction in much larger numbers than have been previously examined. The authors note several limitations to the observational study; however, 1 additional important limitation was not mentioned, which may explain the differences seen in this study and in previous pharmacokinetic work. Because previous reports on ATV and buprenorphine had raised concerns regarding a pharmacodynamic reaction, medical providers were encouraged to slowly increase buprenorphine dosing in patients on ATV-based regimens. One plausible explanation, then, could be that providers slowly increased buprenorphine doses allowing for tolerance to the increased buprenorphine levels, thus avoiding the pharmacodynamic effect. The authors did not comment on the rate of dose escalation that occurred in patients on ATV who started buprenorphine. If a slower buildup in the dosing was not employed, it would be more reassuring that previous pharmacodynamic reports may be less concerning than previously reported and would provide greater reassurance to clinical providers who treat both HIV and opioid dependence. Robert Douglas Bruce, MD, MA, MSc


Another group of handicapped children is not included in the HEW figures. D ' [ C osk . P f d Cl . P f nor are thev Provided the Special atten,.. IVC r t:)' IS ro essor an lair erson o. '. tilt: Departlllent of Speech Communication, West tlOn they need In our schools. These are T'irginia University. the thousands probably millions of chill A. S. :'rCetz,Number of Pupils with Handi. . .. caps in Local Public Schools, Spring, 19iO, Dedren and young people who are compartment of Health, Educati(;Jn, and 'Welfare munication apprehensives." pub. no. (OE) 73.11107 (Washmgton: U.s. Gov... .. . " ernment PrintingOffice, 1973). CommUnIcatIon apprehensIOn re-


Vol. 31, Suppl, 2019 S1 Received January 22, 2018, Revised July 16, 2018, Accepted for publication July 16, 2018 Corresponding author: Sung Yul Lee, Department of Dermatology, Soonchunhyang University Cheonan Hospital, 31 Suncheonhyang 6-gil, Dongnam-gu, Cheonan 31151, Korea. Tel: 82-41-570-2270, Fax: 82-41-570-2783, E-mail: firstname.lastname@example.com ORCID: https://orcid.org/0000-0002-6995-4561 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology pISSN 1013-9087ᆞeISSN 2005-3894 Ann Dermatol Vol. 31, Suppl, 2019 https://doi.org/10.5021/ad.2019.31.S.S1


First seat (24), and the first and the first passenger suite that includes a video monitor (26) (22) which is fixed immediately in front of the position of the first seat (24), a first seat a and facing the (24) second passenger suite contrast comprising a second seat which is laterally offset (32) (30), selecting the first and second suite (22, 30) manner so as to connect and divided, a second suite (30 including a second video monitor (34) configured to move parallel to the viewing angle of the passengers seated on the second seat (32) ) and a, seating arrangements of the passenger suite (20).


The Pio XI clinic—featuring contrasting volumes and fine light-and-shadow effects — contains in five stories radiology, surgery and maternity facilities, as well as nurses' living quarters and other services required for its 150 patient bed capacity.
The unique architectural layout of the building is a direct result of both a spatial solution aiming at minimising walking distances from the various services to the patient rooms, and of an attempt to provide the different hospital facilities with the best possible insulation from external noise, as well as with natural lighting.


In this paper, we study the rate of approximation for the nonlinear sampling Kantorovich operators. We consider the case of uniformly continuous and bounded functions belonging to Lipschitz classes of the Zygmund-type, as well as the case of functions in Orlicz spaces.
 We estimate the aliasing errors with respect to the uniform norm and to the modular functional of the Orlicz spaces, respectively. The general setting of Orlicz spaces allows to deduce directly the results concerning the rate of convergence in \(L^p\)-spaces, \(1 \miu p\) < \(\infty\), very useful in
 the applications to Signal Processing. Others examples of Orlicz spaces as interpolation spaces and exponential spaces are discussed and the particular cases of the nonlinear sampling Kantorovich series constructed using Fej\'er and B-spline kernels are also considered.


In November 2013 regional election—forth of its kind— has been
held in Slovakia. In the run for the governor in Banska
Bystrica region, the leader of extreme right LSNS Marian
Kotleba placed second and got into a runoff with Vladimir Maňka
nominated by SMER-SD who nearly crossed the electoral threshold
in the first round which would ensure him victory. Despite the
high margin between the two candidates, Kotleba was able to
beat his rival and was elected governor. The presented study
sheds light on the results of these election. It focuses on the
structure of Kotleba`s support with a concentration on the
presence of Roma minority in the region.


Recently, 5G has become an important mechanism to serve a growing amount of users in the network, which provides enhanced mobile broadband (eMBB) and ultra-reliable low latency communications (URLLC) services. Meanwhile, Carrier Aggregation (CA) is a promising 5G technology which lets users aggregate fragmented carrier components (CCs) to enhance transmission efficiency. This paper addresses 5G scheduling problem in the CA-enabled eMBB–URLLC coexistence network using genetic algorithm (GA). The key idea is first treating the serving time slot of each user equipment (UE) as a gene and combining all genes to form a chromosome, then generating a set of chromosomes as the initial population and letting the population evolve to iteratively select the fittest one as the resource scheduling decision. Up to now, this is the first work using GA for solving the scheduling problem in the CA-enabled 5G network. Simulation results show that our proposed method can serve the most UEs ($4\%$) with the highest throughput ($7.1\%$) and lower delay.


Abstract It is shown that the effects of mesoscale eddies on tracer transports can be parameterized in a large-scale model by additional advection and diffusion of tracers. Thus, tracers are advected by the effective transport velocity, which is the sum of the large-scale velocity and the eddy-induced transport velocity. The density and continuity equations are the familiar equations for adiabatic, Boussinesq, and incompressible flow with the effective transport velocity replacing the large-scale velocity. One of the main points of this paper is to show how simple the parameterization of Gent and McWilliams appears when interpreted in terms of the effective transport velocity. This was not done in their original 1990 paper. It is also shown that, with the Gent and McWilliams parameterization, potential vorticity in the planetary geostrophic model satisfies an equation close to that for tracers. The analogy of this parameterization with vertical mixing of momentum is then described. The effect of the Gent ...


According to the characteristics of practical teaching of higher vocational basic courses, the connotation, types, goals and significance of practical teaching of higher vocational basic courses are discussed, and the teaching status of higher vocational basic courses is analyzed. The practical curriculum system is reverse engineering. According to the training objectives, the reverse design graduation requirements, establish the relationship between training objectives, graduation requirements and practical curriculum system; on the basis of the reverse design of the practical curriculum system, establish a new relationship between the practical curriculum system and the theoretical curriculum system Finally, according to the graduation requirements, the basic curriculum, professional basic courses and professional courses are reversed. Construct a multi-dimensional and three-dimensional practical teaching mode that combines theory with practice, takes practice teaching as the main body, and combines practice inside and outside the classroom


We prove that for each positive integer n, the Vn-equivalence classes of ribbon knot types form a subgroup Rn, of index two, of the free abelian group Vn constructed by the author and Stanford. As a corollary, any non-ribbon knot whose Arf invariant is trivial cannot be distinguished from ribbon knots by finitely many independent Vassiliev invariants. Furthermore, all non-trivial additive knot cobordism invariants are not of finite type. We prove a few more consequences about the relationship between knot cobordism and Vn-equivalence of knots. As a bi-product, we prove that the number of independent Vassiliev invariants of order n is bounded above by (n−2)! 2 if n > 5, improving the previously known upper bound of (n − 1)!.


We analyze the stability of a gyroscopic oscillator interacting with a finite- and infinite-dimensional heat bath in both the classical and quantum cases. We consider a finite gyroscopic oscillator model of a particle in a magnetic field and examine the stability before and after coupling to a heat bath. It is shown that if the oscillator is gyroscopically stable, coupling to a sufficiently massive heat bath induces instability. The meaning of these ideas in the quantum context is discussed. The model extends the exact diagonalization analysis of an oscillator and field of Ford, Lewis, and O'Connell to the gyroscopic setting.


This paper examined the relative contributions of selected demographic and work experience factors as predictive determinants of job satisfaction among agricultural extension agents in the former Imo State ADP. The job satisfaction prediction profile featured only work experience variables, with need satisfaction exercising the greatest predictive ability. Thus efforts at agent job satisfaction should logically emphasise need satisfaction. Keywords: Extension Agents, Characteristics, determinants, job satisfaction.


Robotic guided medical system requires efficient mechanism of compression of Region of Diagnostics Interest (RODI) in medical images to overcome the tradeoff among efficiency and time which is a computationally challenging task. This task involves the requirement of suitable noise filtering, segmentation, critical feature selection especially at corners of RODI and encoding process. This paper proposes a framework namely ICRODI to evaluate a hybrid approach of compression for region of diagnostic interest in Brain MRI as well as for rest of the region. The approaches used are median filter, thresholding as pre-processing and fuzzy c-mean clustering, Harris corner detection, s-shape fuzzy for segmentation and feature point selection optimization. Further alpha hull of the convex hull is used for getting the volume of the mass and finally the wavelet co-efficient based compression is applied. The effectiveness of the proposed ICRODI is validated by evaluating MSE and PSNR for both RODI and Non-ROSI. The average value of the PSRN for RODI is found approximately 49 % higher as compared to the non-RODI and MSE of the RODI is reduced by approximately 33% as compared to the non-RODI after simulating the process on a numerical simulation platform. The achieved results are quite promising and could be optimized for the VLSI implementation in future.


o O NIETZSCHE the most profound art of tragedy was characterized L by a primal conflict between the two opposing, if not necessarily opposite, forces within the human consciousness-the Dionysiac and the Apollonian.' That tragedy became a lost art he attributed to a substitution (by Socrates and his followers, who have come to include most of the philosophers, theologians and intellectuals of the Western world) of a third force for the Apollonian, namely the force of intellectual or verbal evasion which he designated "Socratic."2 The Dionysiac force can be described as man's direct and intuitive awareness of his own consciousness, of its essentially chaotic and infinite nature, and of the ultimately uncontrollable psychic forces there at work. This awareness leads inevitably to pessimism, despair, and death-longing. In order to withstand this appalling vision, in order to gaze at the Gorgon's head and not submit to petrifaction, it was necessary for man to create illusions and to willfully identify the life of the individual with these illusions.3 This process of resisting the despair of the Dionysiac vision through illusion describes the Apollonian force. We have here a purposeful self-deception for "Apollo is ... the soothsaying god,"4 and he who turned to him found life supportable albeit "his Apollonian consciousness was but a thin veil hiding from him the whole Dionysiac realm."5 In tragedy we find "both the fair world of Apollo and its substratum, the terrible wisdom of Silenus, and we can comprehend intuitively how they mutually require one another."6 We need not necessarily agree with Nietzsche that Euripides was too Socratic and meaningful to be truly tragic and thus signaled


Chromatin immunoprecipitation (ChIP) followed by high‐throughput sequencing (ChIP‐seq) has become the gold standard for mapping of transcription factors and histone modifications throughout the genome. However, for ChIP experiments involving few cells or targeting low‐abundance transcription factors, the small amount of DNA recovered makes ligation of adapters very challenging. In this unit, we describe a ChIP‐seq workflow that can be applied to small cell numbers, including a robust single‐tube and ligation‐free method for preparation of sequencing libraries from sub‐nanogram amounts of ChIP DNA. An example ChIP protocol is first presented, resulting in selective enrichment of DNA‐binding proteins and cross‐linked DNA fragments immobilized on beads via an antibody bridge. This is followed by a protocol for fast and easy cross‐linking reversal and DNA recovery. Finally, we describe a fast, ligation‐free library preparation protocol, featuring DNA SMART technology, resulting in samples ready for Illumina sequencing. © 2016 by John Wiley & Sons, Inc.


Abstract Case report - Introduction Behçet's disease (BD) is a systemic inflammatory, variable-vessel vasculitis manifesting most commonly with recurrent oral or genital ulcers and uveitis. The heterogeneous presentation may also include skin, joint, gastrointestinal and central nervous system involvement. There is a geographical prevalence in countries along the "Old Silk Road" and a strong association with HLA-B51 antigen. Paediatric-onset BD commonly has an incomplete clinical picture thereby causing a diagnostic challenge. We present the case of a 10-year-old boy of Lithuanian origin whose history, imaging and results led to a rapid diagnosis which is unusual in the paediatric population. Case report - Case description The patient presented with a 1-month history of abdominal pain, distension and a cough that did not respond to oral antibiotics or inhalers from his GP. His mother recalled swollen proximal interphalangeal joints on both hands, a rash and red eyes approximately 4 days earlier which had now resolved. She also reported mouth ulcers occurring at least once a month from a young age and cold sores without any genital or anal ulcers. He also had a history of reactive arthritis at the age of 3 with bilateral knee swelling and anaemia. He was afebrile, tachycardic with respiratory distress and an oxygen requirement to maintain saturations over 94%. Chest X-ray showed large bilateral pleural effusions and cardiomegaly. Echocardiography confirmed a large pericardial effusion with signs suggestive of tamponade physiology. After admission to PICU he was intubated and sedated to facilitate pericardial and pleural drain insertion. Post-procedure he was haemodynamically stable. Empirical antibiotic therapy was commenced with IV ceftriaxone. Investigations showed a CRP 58mg/L, ESR 37mm/hr, LDH 325U/L, Haemoglobin 98g/L, platelets 223x109 and a blood film showed non-specific changes. All microbiology samples were negative including T spot, mantoux and broncho-alveolar lavage. Serology included negative Anti-Nuclear Antibody, Extractable Nuclear Antigen, double stranded-DNA, and Rheumatoid Factor with normal complements, immunoglobulins and serum amyloid. HLA B51 was reported as positive. Faecal calprotectin was high at 539µg/g Antiphospholipid antibody screen was positive (anticardiolipin antibody 68U/mL, Beta2-glycoprotein 111U/mL). CT demonstrated multiple pulmonary emboli (PE), splenomegaly and moderate volume ascites. Ophthalmology assessment was unremarkable and biopsies taken during oesophago-gastro-duedenoscopy and colonoscopy were normal. He was diagnosed with BD and secondary antiphospholipid syndrome (APS) based on a combination of clinical, radiological and blood markers. Treatment included colchicine as monotherapy, diuretics to manage effusions and dalteparin for the PEs. Case report - Discussion The Consensus Classification of Paediatric Behçet's Disease (2015) requires 3 out of 6 of the following features to diagnose BD; recurrent oral ulcers, genital ulcers, skin involvement, ocular inflammation, neurological signs and vascular abnormalities. Our patient would score 3 out of 6, thereby meeting criteria for diagnosis. The extensive vascular findings on CT are in keeping with variable vessel vasculitis. Antiphospholipid antibodies including Anticardiolipin (aCL) antibeta- 2 glycoprotein I (B2-GP1) and Lupus anticoagulant (LA) are observed in autoimmune diseases including BD, with around 2% of secondary APS cases on the Ped-APS registry being associated with BD. The frequency of vascular involvement is reported to be 5—20% in paediatric series with deep vein thrombosis (DVT) and superficial vein thrombosis (SVT) being most common. The combination of antibodies and levels are important in assessing risk of thrombosis. There is no difference in the acute treatment of thrombosis attributable to APS as compared to other causes. Current guidelines following thrombosis with persistently positive antiphospholipid antibodies is for long-term coagulation. Children are most commonly transitioned from low molecular weight heparin to warfarin for long-term anticoagulation with a target INR of 2-3 following the first thrombotic event. Direct oral anticoagulants (DOACs) are not currently recommended pending further evidence. Recent studies include an RCT in adults with APS which was halted early due to excessive arterial thrombotic events in the rivaroxaban arm and in another study, rivaroxaban didn't reach the non-inferiority threshold. However, recent EULAR recommendations regarding APS treatment in adults concluded that DOACs may be considered in certain settings. Colchicine was chosen as initial therapy based on presentation with history of mucocutaneous involvement and arthritis. Despite widespread inflammation there were no ocular or neurological findings suggesting the need for anti-TNF-a as first line therapy. Case report - Key learning points Paediatric BD is still a poorly understood condition and presents diagnostic challenges. This case highlighted the importance of a thorough history including a full systemic enquiry, without which the diagnosis would have been more difficult. Once the effusions were drained and the patient was started on colchicine, his follow up echocardiograms returned to normal and he has only reported one much smaller mouth ulcer in the last 4 months. Uveitis screening has continued without any clinical concerns. At this stage there is no clinical need to progress to second-line treatment. The patient developed significant needle phobia during his intensive care admission, so DOAC therapy was considered for long-term anticoagulation for the APS, given the lack of need for INR monitoring. However, it was decided to continue on warfarin due to the aforementioned international paediatric guidance.


Note on the Title - Note on Texts - Preface - Eros and Aesthetics - Sexual Drama in the Early Poetry - Sexuality and Death: The Fate of Wilde's Heterosexual Lovers - Eroticism and the Dialogic Form - The Dandy Coup de Theatre: Homosexual Eros and the London Stage - Epilogue: Speaking the Unspeakable - Notes - Index


The present paper discusses ongoing teacher education and teaching practices in the Atendimento Educacional Especializado (AEE, Specialized Education Services). Based on the historical-cultural perspective and on the historical-critical pedagogy, the article debates teachers' practices promoting a school education which favors the learning and the development of students with disabilities, reconsidering the pedagogical practices of the AEE. The presented considerations derive from a project developed with 23 teachers and their practices. The research collects field journal reports and discusses the pedagogical activities and the teaching practices performed with students with disabilities, reflecting about the possibilities of reconfiguration of the teaching practices in the teacher education process. The study considers there is a need of better theoretical education for teachers and of bigger political engagement by the teachers, making them more aware of what underpins their practices so they can contribute to the fight for the right to a quality education for everyone in public school.


This paper proposed main problems of quantity and quality measurement of the research articles published in INKOM journal for 5 years period in informatics, computers and control system. Those three areas have become research missions of The Research Center for Informatics – Indonesia Institute of Sciences. The aim of this paper is to show how to solve research problems above using bibliometric method to analyze bibliography data available in the journal as well as to offer a summary of the research activity in the area including its most important aspects. Bibliographical data are taken from 76 articles published in the journal from May 2007 to November 2011. This paper also discusses how the method is used to measure article distribution, magazine classification category, article subject distribution, authorship patterns, and institutions distribution contributions. Results of the research show that the majority of articles are contributed by multi authors with degree of collaboration 0,553; the journal has already been widely known by the researchers outside LIPI, researchers from non-LIPI institution dominated more on the publication than from LIPI itself. The quantity of research articles increased in 2011 and used more references from scientific articles than the year before. Besides, the research quality also increased and used more cited articles from scientific journal literature than from books.


In a twist drill (60) for taking soil samples, in particular of agricultural land, it consists of a substantially cylindrical drill rod (62) having thereon a substantially flat spiral band (64). The spiral belt (64) tapers from the outside to the boring bar (62) out. It is advantageous if the spiral belt (64) from the outside to the boring bar (64) out tapers at an angle of 2 DEG to 5 DEG, preferably 2.5 DEG to 3.5 DEG.