Introduction and geological background The Evros ophiolites in the Thrace area of northeastern Greece comprise ultramafic rocks and predominantly mafic extrusive rocks that have originated in a volcanic arc-marginal basin setting (Magganas et al., 1991). These ophiolites together with the lowto very low-grade volcanic and sedimentary rocks are regarded as part of the Circum-Rhodope Belt (Papanikolaou, 1997) in the eastern Rhodope-Thrace region. Mid-Late Jurassic age of gabbro in Evros ophiolite was determined by K-Ar hornblende and apatite fission-track data ca. 160-141Ma (Biggazzi et al., 1989). Stratigraphic ages of sediments, both from detrital fragments and in coherent strata, span from Late Permian up to Late Jurassic-Early Cretaceous (Dimadis et al., 1996, Dimadis, Nikolov, 1997, von Braun, 1993 for review). Data on petrology and geochemistry of mafic lavas and greenschists, kinematics, bulk lithologic context and detrital rocks content from the eastern Bulgarian Rhodope, collectively, confirmed the island-arc origin and the subduction-accretion setting of the corresponding parts of the Mesozoic low-grade sequence (Bonev, Stampfli, 2003). Although mafic rocks of the plutonic sequence in the Evros ophiolite were pointed out (Magganas et al., 1991, von Braun, 1993, Papadopoulos, Anastasiadis, 2002) their field occurrences and composition remain poorly known. We report here the field occurrences and preliminary petrologic and geochemical results of intrusive mafic and felsic rocks associated with tholeiite/boninite dykes from the Evros ophiolite. Finally, we discuss their petrogenesis and tectonic implications.


Nutritional status is a major factor in determining the successful outcome of treatment for cancer. The combined effect of cancer, and the treatment for cancer, has the potential to severely impair nutritional status. The purpose of this study was to investigate the incidence and severity oftreatment-related side-effects which affect nutritional status in cancer patients and to determine the sources and helpfulness of information about nutrition which had been utilised by patients. A descriptive study was used to investigate two groups of patients, one group who was receiving chemotherapy, and the other, radiation therapy. A questionnaire developed by the researcher sought information about the occurrence and severity of problems, as rated by patients' self-reports. This study was structured on the theoretical basis of Lazarus and Folkman's theory of stress, appraisal and coping (1984). The diagnosis and treatment for cancer is usually regarded as a stressful event, and this theory posits that patients may use either problemfocussed or emotion-focussed coping styles to cope with the situation. The results of this study indicate that nutritional depletion is a serious problem for this group of patients. Weight loss, which is the principal marker of nutritional status, was experienced by more than 85% of the patients. Patients showed evidence of using emotionfocussed coping styles, where they often did not seek infom1ation about nutrition, and considered they had 11 no real problems • Information from this study may assist healthcare teams who care for patients who are receiving treatment for cancer to focus more on nutrition, and develop educational programmes which meet the needs of these patients more effectively. This information, including patients self reports and recommendations, may also assist the Cancer Foundation ofWestern Australia to develop a booklet which is specifica1ly designed for cancer patients who are receiving treatment and who experience nutritional problems. v


E-mail: email@example.com May 1, 2006Key Words : Maltooligosaccharides, Ionization, MALDI-TOFMS, Molecular sizeCarbohydrates are the most abundant and structurallydiverse compounds found in nature. Unlike linear polymerssuch as proteins and nucleic acids, oligo- and polymericcarbohydrates can form branch ed structures because linkageof the constituentm onosaccharidesc an occur at a number ofpositions. With such a wide range of structural types, carbo-hydrate analysis by mass spectrometry can involve a largenumber of techniques with no single method being ideal forall compounds. Electron impact ionization, for example, isonly applicable to the smaller molecules. Matrix-assistedon (MALDI),i on/nizt ioati pser deasor l


Objective:To evaluate the clinica effects on the treatment of mallet fingers through reconstructing of extensor terminal tendon by binding the transplanted tendon palmaris longus through the bone-tunneland.Method:19 cases in Group A were treated by reconstruction of extensor terminal tendon with binding the transplanted tendon palmaris longus through the bone-tunnel.25 cases In Group B were treated by reconstruction of extensor terminal tendon with pulling out wire.Compared curative effects of two operations.Result:17 cases in Group A took postoperative follow up ranged from 3 months to 8 months.According to TAM functional assessment system,10 cases were excellent,5 good,1 fair and 1 poor,with the choiceness rate of 88.2%(15/17).24 cases in Group B took postoperative follow up ranged from 3 months to 8 months.According to TAM functional assessment system,6 cases were excellent,5 good,5 fair and 8 poor,with the choiceness rate was 45.8%(11/24).There were statistically differences between the 2 groups(P 0.05).The outcomes of Group A was significantly better than the Group B.Conclusion:Application of binding the transplanted tendon palmaris longus through the bone-tunnel are easy and simple to reconstruct of extensor terminal tendon in the treatment of mallet finger,as well as with fewer complications,the result is reliable.


Two methods for calculating the torque exerted by a rotating field upon a particle have emerged: (a) The effective-dipole-moment method and (b) the Maxwell-stress-tensor method. It has previously been assumed that in nonlossy systems, both methods will yield identical results. In this paper we show that significant differences appear depending upon the particle shape


The article deals with the development of opera directing and director's profile in Slovenia between the two wars, taking into consideration Opera and Theatre in Ljubljana. The author states specific influences of theatre directing upon the development of Opera, as well as the interaction with European movements, and treats the most distinguished personalities in the domain of opera directing in Ljubljana.


Near-Earth Object (NEO) Surveyor, a NASA planetary defense space mission, is currently in Phase B with a launch date in 2026. NEO Surveyor is an infrared telescope designed to detect and characterize Potentially Hazardous Asteroids (PHAs). The required sensors leverage the space flight heritage and further development over the last 15 years of HgCdTe arrays to detect infrared light spanning from 4 to 10 μm. NEO Surveyor will employ eight passively cooled HgCdTe Sensor Chip Assemblies (SCAs) across two bands, each band consisting of a 1x4 SCA mosaic to cover a wide field of view. Four of these SCAs have a >5.5 μm cutoff wavelength and cover the shorter 4-5.2 μm (NC1) band, while four SCAs will have a >10.5 μm cutoff wavelength and span the longer 6-10 μm (NC2) band. We present calibration and performance results from two recently produced pathfinder SCAs, one for each band, manufactured by Teledyne Imaging Sensors with development guidance from the University of Arizona, the University of Rochester, and JPL. Both devices demonstrate the requisite low dark current, high well depth, and high quantum efficiency, exceeding mission requirements.


Abstract : Interest in the toxicity of tin compounds dates to the early 1800's when investigators demonstrated that inorganic tin compounds produced muscular weakness, loss of pain sensation, and immobility in dogs (Reiter and Ruppert 1984; Idemudia and McMillan 198Gb). In man, organotins can be assimilated by inhalation, absorption through the skin, and from food and drinking water (Zuckerman et al. 1978). The first documented case of organotin poisoning of humans was in 1880 when workers complained of headaches, general weakness, nausea, and diarrhea after exposure to triethyltin acetate vapors (Reiter and Ruppert 1984). Renewed interest in the toxicity of organotin compounds resulted from a medical tragedy in France in 1954. Stalinon, a proprietary compound of diethyltin diiodide plus linoic acid used to treat furuncles and other skin infections, caused 217 poisonings and 111 deaths (Piver 1973; Duncan 1980; Idemudia and McMillan 198Gb). The identified toxic components in Stalinon were triethyltin contaminants; victims received a total dose of 3 grams over a 6- to 8-week period. Symptoms included constant severe headache, rapid weight loss, vomiting, urine retention, vertigo, hypothermia, abdominal pain, and visual and psychic disturbances. Some of the more severely affected patients had convulsions. Death usually occurred in coma or from respiratory or cardiac failure. In survivors, headaches and diminished visual acuity remained for at least 4 years.


Bluish-grey discoloration of the face after 1 year of treatment with amiodarone in a 54-year-old man with a history of ventricular tachycardia (left). …


This work focuses on enriching the already available theory concerning public sector management. Experiential validation of employing the Balanced Scorecard for the public sector organisations is examined. An interpretive paradigm in combination with an action research strategy was employed in carrying out the study. The data were collected using both focus group discussions and personal interviews. The analysis was through content and interpretation examination. It is assumed that this study, having focused on one authority whose function is to enhance skills development within the information and communications technology sector in South Africa. The results in this work indicate Original Research Article Mopaki and Mutono; BJAST, 18(1): 1-9, 2016; Article no.BJAST.29531 2 that public organisations should endeavour to put people they serve (clients) at the forefront of their strategic plans. This result confirms the results reported by Kaplan and Norton [9]. Still the study findings indicated that bodies that fund public organisations should as well be taken as stakeholders in the organisational strategic plan, and require to be satisfied in order to ensure continuity of funding. Departmental balanced scorecards should be embraced in contrast to an entire organisational balanced scorecard which seems to be a suggestion from some researchers and scholars. The core advantage with this is that it enhances corporation as opposed to individualism and leads to cohesion rather than divisions.


The use of I/sup 131/ to determine intestinal absorption of fats in 18 patients and 16 controls is presented along with technical details. The method is considered to be a valuable diagnostic aid. (OTS)


This is to certify that the thesis "EFFECT OF YOGA PRACTICES AND PHYSICAL EXERCISES ON SELECTED PHYSIOLOGICAL AND BIOCHEMICAL VARIABLES AMONG NON INSULIN DEPENDENT DIABETES MELLITUS WOMEN" submitted to University of Madras, Chennai in partial fulfillment of the requirement for the award of Degree of DOCTOR OF PHILOSOPHY IN PHYSICAL EDUCATION is the record of research work carried out by Ms. N. UMA under my guidance and supervision and that this thesis has not previously been formed on the basis for the award of any degree, diploma, associateship, fellowship, or any other similar title.


In this work, incorporating the effect of the minimum measurable in momentum and maximal length, we studied the thermodynamics property of the Schwarzschild black hole and the Unruh effect. According to this scenario, we see that the black hole temperature cannot be smaller than a certain minimum value . Moreover, we find that black hole mass cannot be larger than a maximum mass value . Considering these findings first we compute the corrected Hawking temperature vs. the mass and examine its characteristic behavior. Then, we derive the black hole's entropy and heat capacity. We find that the black hole is stable when . Finally, we examined the modified Unruh effect. We find that the modified Unruh temperature explicitly depends on α.


Fibiger's announcement of the production of carcinoma in the rat stomach through the agency of nematodes has not as yet been controverted. We wish briefly to record the fact that somewhat similar pictures can be produced by other means of irritation. By suspending in the stomach cavity woolen balls saturated with chemical irritants or by injecting the chemical irritants into the wall itself, polypoid growths of stratified squamous epithelium can be produced. By using celluloid balls with spinous processes these polypoid growths can be made to reach considerable dimensions. When these irritants are applied to the glandular portions of the organ, marked localized thickenings of the mucosa are produced. The chemical irritants cause a marked downgrowth of stratified epithelium resembling the cancroid type described by Fibiger, while the mechanically induced proliferations are characterized by a marked overgrowth of the cornified layers and relatively slight downgrowth. In the glandular portions of the organ the proliferation under chemical irritation assumes the character of a cystadenoma which involves the stomach wall to a considerable depth.


If information enters memory under the influence of a memory-enhancing substance, for about 16 hours thereafter the recollection of that information is no better than if it had been acquired without any treatment. Later tests of retention, however, performed one or more days, or even weeks, after the experience, show a drug-induced improvement of memory. Memory-enhancing compounds thus appear to facilitate the formation of the long-term memory trace. On the assumption that differences between treated and untreated animals emerge from that moment on when memory is based on the products of the processes modulated by the drugs, it can be postulated that long-term memory comes into play after about 16–20 hours.


Atherosclerotic plaque rupture is the most common mechanism responsible for a majority of sudden coronary deaths. The precursor lesion of plaque rupture is thought to be a thin cap fibroatheroma (TCFA), or "vulnerable plaque". Virtual Histology-Intravascular Ultrasound (VH-IVUS) images are clinically available for visualising colour-coded coronary artery tissue. However, it has limitations in terms of providing clinically relevant information for identifying vulnerable plaque. The aim of this research is to improve the identification of TCFA using VH-IVUS images. To more accurately segment VH-IVUS images, a semi-supervised model is developed by means of hybrid K-means with Particle Swarm Optimisation (PSO) and a minimum Euclidean distance algorithm (KMPSO-mED). Another novelty of the proposed method is fusion of different geometric and informative texture features to capture the varying heterogeneity of plaque components and compute a discriminative index for TCFA plaque, while the existing research on TCFA detection has only focused on the geometric features. Three commonly used statistical texture features are extracted from VH-IVUS images: Local Binary Patterns (LBP), Grey Level Co-occurrence Matrix (GLCM), and Modified Run Length (MRL). Geometric and texture features are concatenated in order to generate complex descriptors. Finally, Back Propagation Neural Network (BPNN), kNN (K-Nearest Neighbour), and Support Vector Machine (SVM) classifiers are applied to select the best classifier for classifying plaque into TCFA and Non-TCFA. The present study proposes a fast and accurate computer-aided method for plaque type classification. The proposed method is applied to 588 VH-IVUS images obtained from 10 patients. The results prove the superiority of the proposed method, with accuracy rates of 98.61% for TCFA plaque.


Introduction: The risk of developing pulmonary tuberculosis (PTB) increases with concurrent nutritional deficiency, of the specific nutrients, social and environmental conditions. PTB, on the other hand, gives rise to both muscle andfat wasting due to loss of appetite and increased catabolic activity. It is also associated with an increased risk of relapse and secondary Multidrug Resistant (MDR) TR Indoor air pollution, smoking and alcohol are well known strong predictors and surprisingly still quite prevalent in rural and urban areas. Methodology: A cross sectional study was carried out over a period of 06 months in PTB cases, above 15 years of age, attending the DOTS centres in an urban area. Extra PTB cases were excludedfrom the study. The sample size was worked out to be 118. Results: Overcrowding was present in 76 (64.4%) of the respondents, 91 (77.1%) had kitchen within the living rooms and 52 (44.1%) of them used cylinders (LPG) and kerosene oil as the cooking fuel Current smoking was reported by 70 (59.3%) patients, and 44 (37.2%) reported alcohol consumption. Of the 118 respondents, 10 (8.2%) had HIV/AIDS and 31 (26.2%) had Diabetes as co morbidities. Around, 69 (58.5%) of them had low BMI (Thinness), PBFwas low in 83 (70.3%) cases andSMM was low in 80 (72%) cases. Conclusion: Proper dietetic advice, taking into consideration local dietary preferences, may be required to be included in the TB management protocol at the DOTS centre. Indoor air pollution needs to be curbed in our society both in the rural as well in the urban area by empowering the community with better fuel.


The synthesis and crystal structure of tridentate pyridine-2,6-dicarboxylate CuII complex with a heterocyclic pyrazole ligand, a potential candidate for metal catalysts, are reported. The CuII atom is coordinated by three O atoms and two N atoms, provided by a tridentate pyridine-2,6-dicarboxylate, one pyrazole and one water ligand, forming a slightly distorted square-pyramidal geometry.


Abstract
Muslim scholars have done great contribution to the field of Comparative Religion in Islamic heritage. In contemporary era numbers of Muslim experts appear in the field of studying religions, names such as Aḥmad Shalabī, Abū Zahrah, al-A'ẓamī, al Fārūqī and 'Irfān 'Abd al- Ḥamīd Fattāḥ are among them. This paper aims at shading light to the efforts, methods and contributions of al-marḥūm Faṭṭāḥ's in his work of studying Christianity and other religions. A qualitative methodology in which the critical textual analysis approach has been used in studying materials related to Faṭṭāḥ. Findings indicate that Faṭṭāḥ presented Christian faith in consistence with the historical development of Christianity..


The invention relates to a hinge connection for converting a linear movement into a pivoting movement with a linearly movable actuating member (17) arranged with an on the actuating element (17) ball joint head (19), wherein the ball joint head (19) (for at least partially transmitting the linear movement of the actuating element 17) (on a rotary member 20) (with the rotary element 20) is connected. To substantially avoid, in particular transversely to the main direction of action, acting on the rotary member forces directly on the actuating element as well as for ease of assembly and reduction of the encumbrance of the hinge joint is characterized in that the rotary element (20) to a locally fixed axis of rotation (21) rotatably supported , and the ball joint head (19) is displaceably guided in the rotary member (20).


A guide to resources in political science. Information on finding books in the library's catalog and in the database Worldcat.


Facial expression recognition plays a key role in human-computer emotional interaction. However, human faces in real environments are affected by various unfavorable factors, which will result in the reduction of expression recognition accuracy. In this paper, we proposed a novel method which combines Fine-tuning Swin Transformer and Multiple Weights Optimality-seeking (FST-MWOS) to enhanced expression recognition performance. FST-MWOS mainly consists of two crucial components: Fine-tuning Swin Transformer (FST) and Multiple Weights Optimality-seeking (MWOS). FST takes Swin Transformer Large as the backbone network to obtain multiple groups of fine-tuned model weights for the homologous data domains by hyperparameters configurations, data augmentation methods, etc. In MWOS a greedy strategy was used to mine locally optimal generalizations in the optimal epoch interval of each group of fine-tuned model weights. Then, the optimality-seeking for multiple groups of locally optimal weights was utilized to obtain the global optimal solution. Experiments results on RAF-DB, FERPlus and AffectNet datasets show that the proposed FST-MWOS method outperforms various state-of-the-art methods.


A single-layer microstrip structure with variable line width is considered in order to create, by periodic repetition, an electromagnetic bandgap structure. The width of the line is varied in such a way as to guarantee a sinusoidally modulated value of the effective dielectric constant along the longitudinal direction. By repeating periodically the structure in the orthogonal direction, a high-impedance surface is obtained. Continuous and discrete line configurations are considered, and the performances of the two-dimensional structure with respect to the uniform line case are compared


Optical flow as an image processing technique finds its applications in many areas of computer vision. A lot of research has been carried out in order to improve optical flow detection techniques, but this field is not perfect even as of today .Many methods have been proposed to solve the optical flow problem however, instabilities at the boundaries of moving objects are still challenges. There are many methods to extract optical flow, yet there is no platform that brings out comparison on the performance of these methods. In this paper, the two major optical flow algorithms are stated. Also I propose two methods of coarse to fine estimation to improve results of basic approach.


Most anti-erosive role have the rootage of beech (Fagus orientalis) 58 % and chestnut (Castanea sativa) -77 % concentrated in 10 sm topsoil, equal distribution of oak and hornbeam (Carpinus caucasica) on the coat of soil, while yuniper (Yuniperus foedissima) 80 % and oriental hornbeam (Carpinus orientalis) -86% at a depth of 0-20 sm.


This article describes the infra red detector manufactured by Coeval which is designed to reduce bridge strikes by high vehicles. Modulated infra red beams of light are used to overcome the problems which were experienced in bad weather with the initial system which used incandescent lamps and reflective infra red. Two varieties are available, one for girder bridges and the other to protect arched bridges where certain high vehicles can pass through if they are moved to the centre of the road. A detection accuracy of plus or minus 1mm in still air is claimed. The infra red beams are usually set at the signed height of a bridge and can be separated by up to 35 metres. Generally, the systems are fitted to modified street lighting columns situated about 100 metres from a convenient alternative route before reaching the bridge. When an 'over-height' vehicle is detected a fibre optic sign mounted close to the alternative route is activated, instructing the driver to divert or turn back as appropriate. Inductive loops are also present to verify vehicle presence to supplement the system and combat the problem experienced with low flying birds. A sign which constantly adjusts its brightness to ambient light level has been incorporated in the design. Trials with the system in Edinburgh have indicated that the system could reduce bridge strikes by as much as 80%. (Author/TRRL)


The paper undertakes certain special forms of the quarter symmetric metric and non-metric connections on an ε-anti-Kähler manifold. Firstly, we deduce the relation between the Riemannian connection and the special forms of the quarter symmetric metric and non-metric connections. Then, we present some results concerning the torsion tensors of these connections. In addition, we find the forms of the curvature tensor, the Ricci curvature tensor and scalar curvature of such connections and we search the conditions for the ε-anti-Kähler manifold to be an Einstein space with respect to these connections. Finally, we study U(Ric)−vector fields with respect to these connections and give some results related to them.


The feasibility of an optical fiber amplifier as a booster amplifier for transmitter-terminals of free-space coherent laser communication systems has been investigated. To enhance the amplifier's efficiency and reliability in a harsh space environment a new pumping-scheme has been analyzed and demonstrated in an experimental set-up. The amplifier features efficient multiple serial coupling of the pump light into the multimode core of the double-clad fiber by using directional Y-couplers. Special attention has been paid to fiber-geometry, pump light absorption efficiency in the neodymium-doped single-mode core and the attenuation of pump and signal light.


Lateral sinus thrombosis is a potentially life-threatening complication, if any delay in its diagnosis and management. The altered clinical picture in the era of antibiotics may be misleading. Therefore, early diagnosis, aggressive medical and surgical management are required for successful outcome. Here, we present a pediatric case which was presented with lateral sinus thrombosis secondary to chronic otomastoiditis with successful outcome. A brief review of literature regarding clinical signs, symptoms, and treatment option are discussed.


A model based on a system of balance equations for localised and continuum states is developed to calculate the current − voltage (I − V) and power characteristics of quantum-cascade lasers (QCLs) operating in the terahertz (THz) range. A method for modifying the eigenbasis of the Schrödinger equation by reducing the dipole moments of tunnel-coupled states is proposed to take into account the effect of dephasing on the carrier transport. The calculated and experimental data on the current − voltage characteristics and the dependence of the integrated radiation intensity on current for the THz QCLs lasing at 2.3 THz are compared. The calculated and measured values of the threshold current, lasing current range, and maximum operating temperature Tmax are found to be in good agreement. It is shown that Tmax can be increased by 25 % by reducing the thickness of the top contact layer n+-GaAs of the laser structure under study from 800 to 100 nm.


Under Phase 1 of the Sound Move program that was approved by the voters in 1996, Sound Transit committed to creating an 85-mile commuter rail system in Washington State from Everett to Lakewood. This includes 8.2 miles of track from Tacoma Dome Station to Lakewood. Construction of 1.2 miles of new track within the City of Tacoma is required as well as rebuilding 7 miles of existing rail corridor, purchased from BNSF. Within Tacoma, the proposed alignment offers significant challenges in terms of topography and sensitive adjacent land uses. This paper outlines the process that Sound Transit is undertaking to address some significant operational issues so that it may successfully advance the project. Passenger rail service to Lakewood was to commence in 2008, however, addressing the challenges of the physical terrain and vehicle operations, could delay service until 2010. With the terrain plagued by a steep grade in the range of 3.5% in a dense urban environment, Sound Transit attempts to perform a balancing act – develop an operationally acceptable profile within the Tacoma community at an environmentally acceptable location and at a cost that is within the budget approved by the voters.


This paper propose an algorithm using multiple cryptographic modules to speed up a certification path validation of the X.509 Certificate. The algorithm used not only software cryptographic module but also hardware cryptographic modules in order to speed up transactions. The effect of it was confirmed by the experiment of the server system that had the fast algorithm of certification path validation under the private test environment.


OBJECTIVE OF THE STUDY
To determine the risks and benefits of routine transcervical revision of previous cesarean uterine scar in patients with successful vaginal delivery.

MATERIAL AND METHODS
Retrospective study, over a 10-year period, of a routine palpation practice in the two units of our Obstetric department. Then, a 30-month prospective study comparing, in each unit, two different attitudes toward uterine revision (routine exploration vs symptomatic patients exploration) was conducted.

RESULTS
The retrospective part of our study led us to report 3 uterine ruptures (0.43% of all scarred uterus) and 14 dehiscences (2%) during the ten years. All uterine ruptures were sufficiently symptomatic in order to be suspected prior to scar exploration. No dehiscence needed surgical treatment. Some patients with bloodless dehiscence and no repair had subsequent vaginal deliveries with no scar separation found on uterine exploration. In the prospective part of our study, we found a significative difference in the occurrence of fever (18.9% vs 9.9%; p < 0.05) and antibiotic treatment (22.8% vs 12.7%; p < 0.05) between the two groups based on attitude toward uterine revision.

CONCLUSION
These data suggest that transcervical revision of previous cesarean uterine scar should be performed only in symptomatic patients (persistent suprapubic pain, placental retention, excessive bleeding during labor or delivery) or when risk factors are present (prolonged labor, prolonged expulsive efforts, instrumental extraction).


Individuals with autism spectrum disorders (ASD) exhibit an increased burden of de novo variants in a broadening range of genes. We functionally tested the effects of ASD missense variants using Drosophila through 'humanization' rescue and overexpression-based strategies. We studied 79 ASD variants in 74 genes identified in the Simons Simplex Collection and found 38% of them caused functional alterations. Moreover, we identified GLRA2 as the cause of a spectrum of neurodevelopmental phenotypes beyond ASD in eight previously undiagnosed subjects. Functional characterization of variants in ASD candidate genes point to conserved neurobiological mechanisms and facilitates gene discovery for rare neurodevelopmental diseases.


Background: Working and living at high altitude above 4000m exposes human beings to labor conditions involving chronic intermittent hypobaric hypoxia (CIHH). Approximately 4% of people exposed to s...


Coalbed methane (CBM) is the very important unconventional energy resource. Enhancing extraction is the main method to improve the utilization of CBM and prevent coal mine gas disasters. To reveal the laws of gas migration during the underground gas extraction, the paper established the solid‐gas coupling model, regarding coal as the homogeneous elastic medium with dual pore‐fracture structure and dual permeability and considering the gas dynamic diffusion coefficient. Then, the regulations of gas migration in the in‐seam borehole were simulated by the COMSOL Multiphysics software and verified via the field trials of gas extraction. The results revealed that the permeability increased with time due to the coupling of matrix shrinkage and volume compression of coal, in which the matrix shrinkage played a leading role. The gas seepage velocity at the observation points can be divided into three stages: the rapid rise stage, the stable decline stage, and the stable and invariant stage. The gas extraction rate continued decreasing with time and finally tended to a fixed value. In the coal seam #4 of Zhongxing coal mine, the measured flow rates of three in‐seam drilling holes were in good agreement with the simulation results, which verified the correctness of the theoretical coupling model.


Lack of knowledge of facing strategies in the family, provokes cognitive, behavior and emotional dysfunctions, so in this investigation it described a process on which it is known how use and exercise on parents facing strategies which will help the to be better the familiar nucleon, on an environment of daughters and sons' behavior with educative needs (NEE). The objective of the present work is: propose to the institution a familiar psicho educative program to improve the facing strategies in parents and sons with special educative needs, including in the regular education; type of study descriptive of transversal cut and cuasi experimental design; the used methods are: analytic, synthetic, deductive, inductive, historic- logic, comprehensive and diagnostic. The scenery is "Jose Ingenieros N° 2 " school of Basic Education, with 345 students, and it is taken a sample of 15 represent ants of 10 children with NEE. The used instrument in the pre- test and post- test stock was the of facing strategies (CSI), applied to 15 parents. In the pre-test it is noticed that the 53.33% of the investigated present a high level of social retreat and avoiding problems; after the participation, it is verified in the post-test that the 53.33% in the low level, parents avoid problems and the 40% in a low level of social retreat. The correlation is of r(x y)) = 0,56, positive moderated. Conclusions, parents with children with NEE, after the intervention, they won´t use the high level the strategies to avoid problems and social


We report the implementation of a photonics-assisted RF amplifier for broadband and multiband 5G networks. A 2 Gsymb/s signal with different digital modulation formats at 20 GHz and a 100 Msymb/s high-order digital modulated signal at 6 GHz have been used for characterizing the proposed technology as a function of the RF gain, signal-to-noise ratio and error vector magnitude. Experimental results demonstrate RF amplification, reconfigurability, distortion absence and low phase noise levels through 6, 20 and 38 GHz frequency bands, which have been considered potential for the future 5G networks.


The occurrence of muscular injuries in young athletes of high competition is very frequent and very disabling, having direct implications on their sports performance and their quality of life. To evaluate muscular injuries in young athletes of high competition. Quantitative, descriptive and correlational study. The sample is of nonprobabilistic type for convenience, constituted by 71 young athletes of high competition, of the two sports clubs of the Central Region of Portugal, all being male. The data collection instrument contains a set of sociodemographic characterization questions, sports context and the Nordic Musculoskeletal Questionnaire (Serranheira et al., 2003) to evaluate the lesions. Most of the participants practice soccer (67.6%), followed by basketball (16.9%) and roller hockey (15.5%). More than half of the sample (49.1%)


This work discusses the pressure drop, heat and mass transfer of the finned-tube heat exchangers having 7㎜ tubes and offset strips in dehumidifying applications. It focuses on the fin material saving and the reduction of pressure drop. The experiment was conducted using three times scaled-up models to simulate the performance of the prototype. Eight kinds of fins having different strips and S shape edges were tested. The area density of the strip was a major factor and its shape and the location were secondary factors on the pressure drop, the heat and mass transfer. The reduced-area fin can almost equal the non-reduced fin in the aspect of heat and mass transfer. The strip fins proposed in the present work can considerably reduce both the pressure drop and the fin material for a similar thermal load.


Vikash Kumar Rai, Indian Institute of Technology Patna, Patna, Bihar, India. Email: email@example.com Abstract Nowadays, physical unclonable functions (PUFs) are emerging as one of the key building blocks for device authentication and key generation. Although PUF is very useful in the area of hardware security, it is vulnerable to machine learning modelling attacks (ML‐MA) by modelling the challenge‐response pairs (CRPs) behaviour. To this end, this study proposes a novel PUF named MARPUF, which gives good resistance to machine learning (ML) attacks. The study proposed a MARPUF design, where the mapping of CRPs is randomized by implementing two‐round challenges to meet the randomness requirements for ML resistance. Ssome of the popular ML techniques are used to test the ML attack resistance and compare the results with some existing PUFs. We evaluate the performance of the PUF against various parameters like reliability, uniformity, uniqueness, etc. The hardware cost analysis shows that MARPUF requires lesser hardware than the existing ML‐MA resistant PUFs.


The diurnal characteristics of summer precipitation and summer short-duration heavy precipitation were analyzed using rainfall data at regional automatic weather stations from 2006 to 2013 in Tangshan. Results show that the short-duration heavy precipitation had higher nocturnal frequency than overall rainfall in general. The percentage of nocturnal precipitation frequency was 66.4%; the peak value of the accumulated rainfall amount and rainfall frequency occurs at early morning, while the valley value appears in the afternoon. The diurnal variation in the rainfall intensity had two peak value intervals. One peak value was in the afternoon and the other peak value happened in early morning. Nocturnal precipitation showed an increasing tendency from 2006 to 2013. The short-duration heavy precipitation diurnal variations showed clear regional differences. The northeast had the maximum precipitation frequency, while the southwest had the minimum frequency,but with the strongest rainfall intensity. The northeast of Tangshan has higher precipitation frequency because it was ringed on three sides by mountains in the west, east and north, so that the airflow carried by the southeast wind was often upraised by the windward slope to induce severe convective weather. The southwest of Tangshan had the access to the sea, therefore, plenty moisture to produce strong rainfall intensity.Diurnal changes of land-sea breeze had a great role in the formation of the precipitation peaks at 16(CST)in northeast and 4 in southwest.


In this paper, Decision Support System (DSS)for site selection of seawater desalination plant has beendeveloped. The general methodology includes two main steps for site selection. The first stepis togenerate a list of possible locations depending on the criterion of minimizing water transportation cost. This is established by using non-linear objective function.In the second step, the location is optimized using Multicriteria analysis(MCA) taking into account important factors affecting the optimization process.Each factor is given a weight according to its importance from one to eight. As a case study,the developed DSS is applied on coastal cities of northwest of Libya. Those cities located between Ras-EJdarand Musrata.Sample results are shown in this paper in order to explain the developed DSS.


THE PAST SEVERAL YEARS have witnessed a rapid increase in the use of diesel-electric locomotives. In the course of day-to-day operation, the electrical drive of these locomotives is subject to frequent and severe transient load surges. This type of operation — particularly in a locomotive environment conducive to the accumulation of dirt, dust, oil, and moisture — results in commutator flashing to a degree not encountered in usual d-c machine applications.


Laterally coupled, complex distributed feedback lasers based on AlInGaAs/InAs/InP quantum dash layers were fabricated by maskless focused ion beam lithography. Continuous-wave powers above 30 mW at room temperature, sidemode suppression ratios of 44 dB and a modulation bandwidth of 7.6 GHz were demonstrated.


Objective
To observe the changes in the period of acute stress in rat blood glucose and brain tissue moisture content, in order to provide anti-stress test basis of improving the ability of the severe acute stroke patients.

Methods
Sixty-four SD male rats were randomly divided into two groups: (1) control group, fed deionized water a week, intraperitoneal injection of 10% of the phenylephrine-induced vasogenic brain edema caused by acute (Vasogenic Brain Edema, VBE) model, and observe the changes of blood glucose, brain edema, SOD, and MDA after modeling 1 h, 2 h, 6 h and 12 h; (2) experimental group, fed vitamin C, vitamin E, L-arginine, glutamine, magnesium chloride and decoction for Invigorating Yang composition of complex nutrients for a week, the modeling methods, blood collection time points and observed targets same with the control group.

Results
Blood glucose, brain tissue moisture content among the two groups, were significantly different, P<0.05, and the experimental group are better than the control group.

Conclusions
Early given Chinese-western anti-stress compound nutrients can significantly improve the body's anti-stress capability.

Key words:
Severe brain edema; Anti-stress; Nutrition; Chinese traditional medicine


Fresh catfish (Clarias gariepinus) is highly perishable. This paper aims to investigate the drying characteristics and quality of body-mass dehydrated catfish to determine the effective dehydration parameters for preservation.,Brine concentration (3-9 per cent), brining time (30-90 min) and drying temperature (90-130°C) interacted using the response surface methodology. Preliminary experiments were conducted to select treatments. Moisture content and ratio and drying rate were determined and fitted into five thin-layer drying models; the goodness of fit was evaluated by average grade ranking of the regression parameters. Proximate compositions and microbial load of dehydrated catfish were determined using standard methods.,Treatments with 110°C gave initial higher drying rate (0.034-0.043 kg H2O/kg solid/h) and shorter drying time (20-21 h). Drying occurred at two falling rate periods. Midilli model ranked first in fitting the drying data. It explained up to 99.6-99.7 per cent of the total variations in the independent variables with low values of error terms; RMSE was 0.02131-0.01794 and χ2 was 0.00037-0.00043, indicating good predictive quality. Processing parameters positively and significantly (p < 0.05) influenced the proximate compositions of dehydrated catfish. Treatment: 6 per cent brine, 90 min and 110°C presented the most effective dehydration parameters for quality preservation of body-mass catfish.,The dehydration technique used in this study could enhance nutritive quality and storage stability of body-mass dehydrated catfish that could serve as a useful and convenient tool for commercial application.,Hygienically processed dehydrated catfish of good quality could be used as a source of nutrients to ameliorate malnutrition and reduce post-harvest losses of catfish.,The effective processing parameters established is an important step to harness the high nutrients and economic values embedded in catfish.


The purpose of this study is to analyze needs of bilingual education for children of multicultural families, specially the bilingual classes performed by multicultural family support centers in Korea. Following a brief overview of the meaning and goals of bilingual education, the present study provides the results of the survey that was conducted on 45 program managers, 55 teachers, and 114 mothers of multicultural children who take bilingual classes. The results indicate that the current status of the bilingual programs reflects that of multicultural families in Korea. For example, the number of Korean-Chinese bilingual programs is the biggest one as that of immigrant women through marriage from China. The findings from this research tell us that the programs play efficient roles for improving the bilingual abilities of multicultural children although there remain many problems in terms of systematized curricula, interesting materials, and teacher training. Most of respondents (managers and teachers) say that they need to have standard teachers' manuals and workbooks for better educational services. The results of the analysis also show that it is urgent and important to enrich the substance of teacher training programs for enhancement of bilingual teachers' qualification.


Prior research has investigated the upside value of investing in intangible assets and knowledge creation. This study looks at the downside of not investing in intangible assets. The lack of intangible assets suggests firms are not creating future opportunities and at the worst may be subject to financial distress. The empirical analysis indicates that firms without intangible assets are more prone to bankruptcy and financial distress.


The term "budget" hotel has become a buzz word in the hotel and catering industry. It is argued that it is a misnomer as it implies a homogeneous product when, in fact, "budget" hotels are highly segmented. The major segments are identified and the implications of "budget" concepts for hotel companies and their customers considered.


This paper presents a novel porous media model for homogenized free surface flow, representing wet‐out composites processing. The model is derived from concepts of homogenization applied to a compressible two‐phase flow, accounting for capillary effects and the concept of relative permeability. Based on mass balance considerations, we obtain a nonlinear set of equations of convection‐diffusion type involving the mixture (fluid) pressure and the degree of saturation as primary fields. A staggered Galerkin finite element approach is employed to decouple the solution. Moreover, the streamline upwind/Petrov‐Galerkin technique is applied to attenuate the oscillations in the saturation solutions. The model accuracy and convergence of the finite element solutions are demonstrated through 1‐dimensional and 2‐dimensional examples, representing resin transfer molding flow processes.


Nutrition is one of the factors that influences bone mineralization (BM). We have shown that the Chilean teenager has a low calcium intake during a period of rapid calcium accretion, which may favor osteoporosis in adult life. Thus, we evaluated the influence of a low calcium intake on BM in school age children. We studied 36 children with calcium intakes below the recommended allowance (RDA) and 28 controls of the same age and sex with an adequate calcium intake. Calcium intake was measured by three 24 hour recollection surveys, the percentage of adequation of weight for height (W/H) according to WHO tables, and puberal development was assessed by the method of Tanner. Bone mineral density (BMD) and total bone mass (TBM) were determined in whde body, spine and hip, with a Norland densitometer (Gd 156). The group with calcium intake below 50% had a lower % of adequation of height for age (97.7 ± 4.0%), TBM (98.9 ± 17.9) and BMD (97.8 ± 11.1%) in whole body compared with the group with intake over 100% (115.9 ± 17.4; 109.7 ± 18.0 and 104.7 ± 11.1%, respectively). In spine and hip there was a clear tendency for a lower TBM and BMD, which did not reach statistical significance. The recollection survey showed a lower protein intake in the group with low calcium intake compared with controls. The influence of isolated calcium deficit or in combination with protein deficit upon skeletal mineralization is discussed.


Fractured reservoirs contain about 85 and 90 percent of oil and gas resources respectively in Iran. A comprehensive study and investigation of fractures as the main factor affecting fluid flow or perhaps barrier seems necessary for reservoir development studies. High degrees of heterogeneity and sparseness of data have incapacitated conventional deterministic methods in fracture network modeling. Recently, simulated annealing (SA) has been applied to generate stochastic realizations of spatially correlated fracture networks by assuming that the elastic energy of fractures follows Boltzmann distribution. Although SA honors local variability, the objective function of geometrical fracture modeling is defined for homogeneous conditions. In this study, after the introduction of SA and the derivation of the energy function, a novel technique is presented to adjust the model with highly heterogeneous data for a fractured field from the southwest of Iran. To this end, the regular object-based model is combined with a grid-based technique to cover the heterogeneity of reservoir properties. The original SA algorithm is also modified by being constrained in different directions and weighting the energy function to make it appropriate for heterogeneous conditions. The simulation results of the presented approach are in good agreement with the observed field data.


This paper investigates how reward-to-risk ratios compare among various government debt security (GDS) indices and sector indices in the Istanbul Stock Exchange. Risk is measured by either standard deviation or nonparametric and parametric value at risk. We find that the GDS indices have higher reward-to-risk ratios compared to the sector indices. GDS indices with longer maturities have lower reward-to-risk ratios and this reduction is especially pronounced when the ratios take downside risk into account. The reward-to-risk rankings for the sector indices are similar for each measure and the results are robust to currency conversion.


Subjective: Interspecific embryo transfer could be a valuable tool in preservation programs of endangered species.The majority of previous studies focused on descriptions of microstructure and anatomic differences between intraspecific and interspecific pregnancy,while the report for molecular mechanism of these phenomena was few.The aim of this work was to illuminate the difference of immunological reaction between intraspecific and interfamily pregnancy and to primarily grope for the possible reasons of interfamily pregnant abortion.Methods: The fetuses of interfamily pregnancy day 4,day 8 and day 12 were acted as experimental group,while the ones of intraspecific pregnancy day 4,day 8 and day 12 of embryo transfer and the uteri of pseudopregnant mice of corresponding time were employed as positive and negative groups respectively.Results: The indirect immunofluorescence and laser confocal scan results of cryosections showed: Expressive positions and intensities of MHC class Ⅱ molecules and Gal-α-Gal epitopes were all different in interfamily pregnancy,positive and negative controls in pregnancy day 8.The expressions of MHC class Ⅱ molecules in interfamily pregnancy were weaker than in intraspecfic pregnancy in day 8,and expressive modes in day 12 were also different.Gal-α-Gal epitopes did not expresse in interfamily pregnancy day 8,but in intraspecific pregnancy they expressed in a certain level.In pregnancy day 12,they expressed in a certain degree in interfamily pregnancy,but their expressive modes were different to those in intraspecific pregnancy.Conclusion: These results indicated the differences between interfamily and intraspecific pregnancy.It was possible that these different expressions of MHC class Ⅱ molecules and Gal-α-Gal epitopes would be one of the reasons leading to the failure in interfamily pregnancy.


Objective To explore the clinical efficacy of mini-laparotomy cholecystectomy treating patients with gallstones combined with cholecystitis. Methods 70 cases with gallstones combined with cholecystitis treated in our hospital from December 2010 to December 2012 were selected as research objects and divided into the control group and the observation group.The control group was treated with traditional cholecystectomy,and the observation group was treated with mini-laparotomy cholecystectomy.The clinical efficacy of two groups were compared. Results The operation time,bleeding amount in operation,length of stay and evacuation time of the observation group were longer than those of the control group.The operation effect of the observation group was evidently better than that of the control group.In the control group,there were 2 cases with bleeding after operation,1 case with biliary fistula,1 case with choledochus injury and 2 cases with infection.The incidence rate of complications after operation was 17.1%.In the observation group,there was 1 case with infection after operation,and the incidence rate of complications after operation was 2.9%.The incidence rate of complications in the observation group was lower than that in the control group. Conclusion Mini-laparotomy cholecystectomy treating patients with gallstones combined with cholecystitis has evident efficacy and is safe,which is worthy of clinical promotion.


This paper discusses the theory and design of a tactical channel simulator (TCS) built to simulate land-mobile VHF radio links. The instrument is one of the first such units based on the stored channel principle, which permits the actual medium to be recorded and played back. The key application of the TCS simulator is to realistically reproduce field conditions in a laboratory. Tests on the TCS simulator should be in good accord with performance encountered in the field, unlike results obtained in the standard back-to-back tests which ignore effects of the propagation channel. Experimental results show that the evaluation of modem performance must take into account the effects of propagation over the VHF channel, as data tests are measurably affected by channel conditions. The TCS simulator will be particularly useful in the comparative evaluation of various highspeed, high-performance modems now being introduced into the inventory.


Purpose: To compare success and complications using 6fr (thin) semirigid URS with 8fr (standard) semirigid URS in treating ureteric stones.
Material & Methods: Group 1 , 52 patients treated for ureteric stones with thin URS and the same number treated with standard URS in Group 2 , were compared retrospectively using a matched pair analysis. The size , side ,location and impaction of the stones and also the age, gender, body mass index (BMI) and the presence of hydro-uretronephrosis were used as matching parameters, stones were fragmented with pneumatic energy.
Results : The matching parameters were comparable between the 2 groups. The stone free rates were 88.5% and 84.6% in group 1 and 2 , mean operative time was 32.7+- 5.8 min and 30.2+- 5.4 min in group 1 and 2 respectively. Post operative haematuria was seen in 1.9% and 13.5% patients in group 1 and 2 , Ureteral balloon dilatation was seen in 1.9% in group 1 as compared to 13.5% in group 2, Mucosal injury was seen in 1.9% and 13.5% in group 1 and 2 respectively .No major complications seen in either groups.
Conclusion: Though stone free status and operative time was similar in both groups, a thin 6fr URS can reduce the need for ureteric dilatation and has less minor complications as mucosal injury and post operative haematuria in patients.


Firms have recently faced the twofold challenges of the abrupt deterioration of the global economy and continual rise in customer demands and expectations. Enterprise Resource Planning (ERP) benefits a firm in cost minimisation and service level enhancement. American Telephone and Telegraph Company (AT&T), the largest telecom service provider in the USA, is selected to be studied in this paper. We investigate the critical elements of their ERP implementation process. We also illustrate comprehensive approaches such as Cost-Benefit Analysis (CBA), Multiple Linear Regression and Intensity Indices to evaluate ERP performance. Findings show that ERP implementation decreases dependence on capital investment, but not for operating expenses. This study also found that AT&T reacted faster than the market average in terms of IT investment, and the Intensity Indices have shed some light on how this trend is derived.


Aiming at the integrated surgical robot, a set of power-assisted control system is designed to overcome the transmission resistance between master and slave hands, so that the operator feels light and comfortable during operation. The system includes permanent magnet synchronous motor, driver, controller, torque sensor, upper computer. The field oriented control algorithm is discussed and is used to control the permanent magnet synchronous motor. STM32 is used as the main control chip, DRV8301 is used as the driving chip, and the upper computer software, which has human-computer interaction interface and real-time torque signal display interface, is written by C#. A non-contact torque sensor and corresponding signal processing module is designed. The experimental results show that with the operator's start-stop and reversing action, the q-axis current of the motor changes rapidly, and the amplitude of steady-state changes is small. This means that the designed system has the advantages of stable assist torque and fast response.


The effects of composi tion on delta ferrite and martensite formation were studied in chill-cast experimental stainless steel alloys. Nickel content was varied in each of seventy different alloy types to pro duce structures ranging from fully stable austenite to ones containing high percentages of delta ferrite or martensite. The nickel or chromium equivalents of Mn, Mo, Si, V, W, Ti, Cb, Ta, Al, C, N, Co and Cu were evaluated by regression analyses.


A novel methodology for the calculation, visualisation and analysis of the Reconfigurable Machinery Efficient Workspace RMEW, based on the twist angles, is presented in this paper. The machinery's kinematic parameters are used for calculating the workspace, while the efficient workspace is associated with the machinery's path and includes the end-effector position and orientation. To analyse and visualise many different machinery efficient workspaces at the same time, the calculation is based on the previously developed and validated complex reconfigurable machinery's kinematic structure named n-DOF Global Kinematic Model n-GKM. An industrial robot is used as an example to demonstrate an application of n-GKM model. It is calculated only for the tool's perpendicular orientation relative to the floor. Four different kinematic configurations based on twist angles α


The printed image of a layout that satisfies the double patterning lithograph (DPL) constraints may not have good fidelity if the layout neglects optical proximity correction (OPC). Simultaneously considering DPL and OPC becomes necessary when gene rating layouts, especially in routing stage. Moreover, one decomposed design with balanced mask density has a lower edge placement error (EPE)than an unbalance done[6]. This work proposes a compre-hensive conflict graph (CCG)to enable detailed routers to simultaneously consider DPL, OPC, and mask density to gene rate litho-friendly layouts. This work then develops an DPL-aware and OPC-friendly gridless detailed routing (DOPPLER) by applying CCG in a gridless routing model. A density variation threshold annealing-based routing flow is also proposed to prevent DOPPLER from falling into a sub-optimal mask density balance. Compared with existing DPL-aware detailed routing works, DOPPLER demon-stratesanaverage 73.84% of EPE hotspot reduction with a satisfactory mask density at the cost of an average increase of 0.08% wire-length, 15.14% number of stitches, and 77.28% runtime.


Multichannel signal enhancement is an important task, e.g., in modern speech communication. It can be approached in a mean-square error sense by multichannel Wiener filtering, which is often implemented as a cascade of spatial beamforming and spectral enhancement postfiltering. In this paper, we propose a novel Bayesian perspective on the problem of postfilter adaptation. Specifically, we present a two-step procedure for postfilter estimation. We first derive maximum-likelihood (ML) optimal estimators of the target signal and noise power spectral densities (PSD) employing the high-dimensional receiver data in conjunction with blindly estimated channels. When constructing a Wiener postfilter for noisy speech based on the respective speech and noise PSD estimates, this ML-based postfilter is capable of performing good speech enhancement, while leaving musical noise. Hence, we extend to a Bayesian estimation approach in a second step. By statistically modeling the ML-based postfilter estimation and further proposing a prior for the ideal Wiener postfilter, we derive a Bayesian refinement of the ML-based postfilter. This refinement then solely depends on the ML-based postfilter and is independent of the underlying high-dimensional data. Our Bayesian refinement is therefore implemented as a lightweight table look-up. Both proposed postfilters perform well in terms of segmental signal-to-noise ratio and perceptual evaluation of speech quality in various acoustical setups with nonstationary noise. The Bayes-refined postfilter offers consistent improvement over the ML-based postfilter and a single-channel speech enhancement baseline.


Items with Radio Frequency Identification (RFID) tags can be sold from an old owner to a new owner. An Ownership Transfer (OT) protocol allows the transfer of tag ownership from one owner to another. In this work we present a secure, two-party ownership transfer protocol (TP-OTP) for an RFID tag. TP-OTP uses the quadratic residue property to privately convey secrets between the tag and each owner. Our scheme is EPC compliant and uses lightweight mechanisms that passive tags can accommodate. Further, old and new owners need not to be in range of the tag at the same time. Comparisons on security, privacy, and efficiency with other two-party OT protocols demonstrate the merits of TP-OTP.


The structure and dielectric properties of Bi2O3-ZnO-Nb2O5(BZN) pyrochlore ceramics doped with Fe3+ were investigated. The crystal structure of (Bi1.5Zn0.5)(Zn0.5Nb1.5-xFex)O7 (BZNF) ceramics is cubic pyrochlore structure (α-BZN) when x ≤ 0.1 mol and the second phase occurs at x = 0.135 mol. The lattice parameter increases with increasing Fe. When x ≤ 0.1 mol the dielectric constant decreases and the dielectric loss increases. All the compositions exhibit a typical relaxation behavior. The modified Curie-Weiss law is used to characterize the dielectric relaxation. With an increase in Fe concentration the Tm shifts towards lower temperature, the bond lengths of RA-O and RB-O slightly increase and the ξ fractional coordinate of O decreases until x = 0.135 mol, meanwhile the bond valence sum AV (O) decrease.


Introduction The impact significance assessment is an essential step in Environmental Impact Assessment, aiming at determining what is important or acceptable. Significant impacts need to be adequately addressed, requiring commensurate mitigation, and being grounded on a robust baseline and impact prediction (Duarte and Sánchez, 2020). There is no "best" or "effective" procedure to significance determination practice is variable and should be fit to context (Lawrence, 2007a; 2007b).


Ammophila arenaria (Marram grass) is the most dominant sand-fixing plant species in the Dutch coastal foredunes. This species has a natural ability to emerge from being buried and is therefore used to stabilize the coastal foredunes. On seaward slopes where plants are buried regularly with windblown sand, plants retain their vigour, but start to degenerate when sand accumulation diminishes. One of the factors that may cause degeneration at stabilized sites is the infection of roots by nematodes and fungi. Burial by fresh windblown sand may enable the plants to overcome these harmful soil organisms. In the present study, the nature of the soil-borne disease and its relationship with sand deposition is investigated. In a field survey, a wide range of nematodes and fungi were isolated from the root zone of A. arenaria . Subsequent inoculation-experiments showed that adding single fungal species did not reduce the growth of seedlings whereas combining all commonly found fungi together did, thus indicating synergistic effects. Adding 80 times more individuals of the semi- endoparasitic nematode Telotylenchus ventralis than present in natural soil reduced the growth of seedlings to the same extent as in natural soil. Several groups of soil organisms, especially those groups that include plant-parasitic nematodes, have shown to affect the growth of A. arenaria Burial with unsterilized root zone sand was less beneficial for plant growth than burial with sterilized or beach sand. This implies that plants are able to escape infection by soil organisms through upward growth following sand accumulation. Fungi colonized the freshly deposited layer of sand faster than plant-parasitic nematodes. Furthermore, it could be shown that in windblown soil numbers of fungal propagules and nematodes were reduced. Rejuvenation of stands along the accumulating edges of blowouts can, therefore, be explained by the reduced inoculum pressure of plant-pathogenic organisms in the deposited soil. The amount of sand and the time when sand is deposited are important components in the chances of A. arenaria to escape infection by soil organisms.


Transcription activator CBF1 is a trans-acting factor,which can be induced by low temperature.Derived from Arabidopsis,the CBF1 gene is Successfully cloned with PCR.Then CBF1 cDNA and plant expression vector pBI121 are conjugated to construct the recombinant plasmid pBI121-CBF1.Establish the foundation of introducing the arabidopsis transcriptional factor gene CBF1 into forage grass with agrobacterium mediated transgene technique.


Anisocoria is pupil's asymmetrical reaction to light. The etiology behind anisocoria is mostly due to disorders affecting the sympathetic and parasympathetic pathways. Possible etiologies for unilateral midriasis include parasympathetic denervation (CN III palsy), Adie's tonic pupil, traumatic and pharmacological mydriasis and acute glocoma crises. The most common etiology that leads to unilateral miosis include sympathetic denervation (Horner syndrome), pharmacological miosis and iridocyclitis. It may not always be easy to evaluate anisocoria or the abnormal pupil. A careful neuro-ophthalmological exam and differential diagnosis is warranted in patients who present with anisocoria. In this article, we would like to present a patient with migraine headache and episodic anisocoria and further discuss the possible pathophysiology of this presentation.


The purpose of this dissertation is to propose a framework for sales and operations planning (S&OP), which is based on a modularized view of supply chains. The framework should support both pro ...


Objective To observe the prevalence of seasickness in 100 students during a first time voyage and to probe its affecting factors in order to provide scientific basis for the prevention of seasickness.Methods 100 male healthy students who had never sailed on the sea were chosen to join a 13 day sea voyage.Symptoms and severity of seasickness as well as its occurrence rates were observed during different sea conditions,including wind speed,surge height,time duration of rough sea,speed of the ship,degree of side sway of the ship, the location,number of room members and ventilation installations of the living cabin.Results The total occurrence of seasickness was 39.0% and for mild and moderate cases were 3.0% and 36.0% respectively.At the 4 th,6 th,9 th and 12 th day of the voyage,the occurrence of seasickness was 37.0%,2.0%,12.0%and 4.0%,respectively;and at the same time,the wind speed was 2.5~8.2 m/s,the surge height was 0.5~1.5 m,the degree of side sway was 4°~12°,and the time duration of rough sea was 1.5~15.0 h.The students in living cabin No.8 b had significantly higher occurrence of seasickness than the students in No.8 a which had better ventilation.Conclusions Most (over 67%)of the seasickness students developed vestibular adaptation within 6~12 days of sea voyage.High sea wave and surge might be the main factors in inducing seasickness.The prolonged duration of the rough sea may increase the prevalence of seasickness and the air quality in the living cabin is considered to be an importante influencing factor.


Correspondence: Yehia Y. Mishriki, MD, FACP, Penn State University College of Medicine, 1210 S. Cedar Crest Blvd., Ste. 3600, Allentown, PA 18103. Tel: 610-402-1150 Fax: 610-402-1153 E-mail: firstname.lastname@example.com Case Report A 75-year-old woman was seen for worsening chronic abdominal pain. The pain was described as "crampy" and was associated with watery diarrhea and nausea. It would start abruptly, was self-limited, and was not relieved with bowel movements. She had tried antispasmodics, acid suppressants, and a lactose-free diet with no effect. Previous multiple imaging studies were all unrevealing. Her medical history included gastroesophageal refl ux disease and a history of Helicobacter pylori and Clostridium diffi cile infections. She had no known allergies and denied tobacco, alcohol, or drug use. Her family history was noncontributory. Physical examination was normal except for mild right-sided abdominal tenderness. There were no peritoneal signs. Laboratory studies revealed low C4, C2, and C1q levels. A computed tomographic scan of the abdomen and pelvis is pictured above. What's your diagnosis? Global reprints distributed only by Postgraduate Medicine USA. No part of Postgraduate Medicine may be reproduced or transmitted in any form without written permission from the publisher. All permission requests to reproduce or adapt published material must be directed to the journal office in Berwyn, PA, no other persons or offices are authorized to act on our behalf. Requests should include a statement describing how material will be used, the complete article citation, a copy of the figure or table of interest as it appeared in the journal, and a copy of the "new" (adapted) material if appropriate


In railway applications, the estimation of the wear in the wheel-rail contact is an important field of study, mainly correlated to the planning of maintenance interven-tions, vehicle stability and the possibility to carry out specific strategies for the wheel profile optimization. In this work Authors present a model conceived for the evaluation of the wheel profile evolution due to wear, which is organized in two parts, mutually interactive: a vehicle model for the dynamic analysis and a model for the wear estimation. The first one is a 3D multibody model of a railway vehicle implemented in SIMPACK, a commercial software for the analysis of mechanical systems; the wheel-rail interaction, based on an innovative contact points research method developed by Authors in previous works, is implemented in a C/C++ user routine of SIMPACK. Normal and tangential forces in the contact patches are calculated according to Hertz and Kalker's global theory respectively. The wear model, developed in MATLAB environment, is mainly based on experimental relationships found in literature between the removed material and the energy dissipated by friction at the contact. It starts from the outputs of the multibody simulations (position of contact points, contact forces and creepages) and estimates the contact pressures by means of a local contact model (FASTSIM algorithm); finally the removed material is calculated and the worn wheel profile is obtained. This approach allows, evaluating both the quantity of removed material and its distribution along the wheel profile, to analyze the development of the wheel shape during its lifetime. In order to reproduce the wear progression, the overall mileage travelled by the vehicle is divided into discrete steps during which the wheel profile is constant; after simulating one step, the wheel profile is updated by means of the wear model. Therefore, the two models work alternately until completing the mileage. The choice of an appropriate length of the step is fundamental in terms of precision and computational time required. The entire model has been validated in collaboration with Trenitalia S.P.A, which has provided the technical documentation and the experimental results relating to some tests performed with the vehicle DMU ALn 501 "Minuetto" on the Aosta-Pre Saint Didier line.


Reviewing How We Review During our term as editors, we've received more than 15,000 manuscripts at the Annals. Several prior editorials have described our policies and even experiments in peer review. A snapshot of the process would include the following statistics: each incoming manuscript is assigned to one of the associate editors based on their expertise; after an internal review 70% of manuscripts are rejected in house, 30% are sent for external review, and approximately 1 in 3 of these are ultimately published. Thus our final acceptance rate is <10%. In house decisions are guided by considerations of novelty, impact, and whether the manuscript is likely to be of interest to a broad community of translational neuroscientists and academic clinicians (1–3). Given the large number of submissions received, we simply do not have room in the journal's pages to include many highly meritorious contributions, and dragging authors through an unfruitful review process is in no one's interest. Those judged to be of high quality but primarily targeted to a subspecialty audience are usually better published elsewhere. We typically return without review genetic and biomarker studies that lack confirmation datasets (4–6). We may ask for reassurance that positive associations are not the result of data-mining. We also have some biases against case reports that are less than extraordinary, or private, usually recessive, genetic mutations identified in a single inbred family. On the other hand, we actively seek out clinical trials, are delighted to expedite highly impactful, practice-changing discoveries, and feel an obligation to give special consideration to data that build upon, or fail to confirm, published work in our pages. For manuscripts that are sent for external review, each is typically reviewed by at least 2, and sometimes by as many as 4–5 referees. At this stage, we rely entirely on the reviews of our referees, and base our final decisions overwhelmingly on their knowledge and depth of experience in their respective areas of expertise. We violate our compact with them whenever we go against their recommendations, especially when the recommendations are concordant. There are more than 200 journals in the clinical neurosciences, and whenever we reject a great paper (and we certainly have a list of those that got away!) (7), this is more of a loss for the Annals than the authors, as strong papers can always find an appropriate home. In fact, a recent study indicated that manuscripts that were sent to more than one journal seem to be stronger than those that go to just one, at least as judged by the number of citations that they received. (8) This is probably because harsh reviews, and rejection, lead to improved manuscripts. Much as we caution our kids not to focus all of their love on one college, it is similarly helpful to remind authors to not focus their aspirations entirely on any one journal. We recognize that some decisions – particularly the borderline ones – may be perceived as unfair; these could result from an attempt to balance content areas, demographics of our reviewers, or simply reflect bad decisions on our part. Over the years, we've also become accustomed to dealing with harsh correspondence from disappointed authors. Some of the verbal jousting has been surprisingly intimate, usually reflecting surprise, anger, and/or aggressive rebuttal of a negative decision – all, perhaps, a consequence of the enviable status of the Annals. We've learned to focus on the scientific arguments and not take the emotional content too personally, remembering the maxim of Nick Carroway (9) that as editors we've enjoyed special "advantages" at the helm of the Annals. We've had access to many of the best new ideas in our field, and also the joy of interacting closely with outstanding colleagues from around the world. Along the corridors of UCSF it is not uncommon to hear us advise mentees to remember that referees are anonymous but authors and editors are not. We've learned through our own professional experiences that it is better to let momentary passions fade through restful overnight sleep before sending out a negative e-mail; counting to 10 is OK, but it is even better to count sheep. Some simple rules of correspondence etiquette we have learned over the years: 1. In rebuttal letters, try to avoid revealing your own Axis II diagnoses; as editors, we have enough problems of our own:


Functional gastrointestinal disorders comprise many unexplained afflictions for which no organic cause can be identified. These disturbances occur worldwide and make up half the gastroenterology cases in the Western world. Diagnosis and management is complicated by the fact that no-one can decide whether the disorders have an emotional or a psychological basis. This book presents a single source of standardized definitions, diagnostic criteria and treatment recommendations for these common conditions. Physicians should no longer need to make a diagnosis of exclusion; this book should provide a consensus document of management and treatment.


Abstract The earliest functional living system on Earth should have been able to reproduce an ordered configuration and a self-organization dynamics. It was capable of resisting a random variability in time and space to keep the functionality. Amino acids (AAs) and nucleobases generated from abiotic reactions as seen in laboratory-based experiments have demonstrated that molecular elements for life can be obtained by predictable physicochemical processes. However, a functional, self-organized living system needs complex molecular interactions to endure. In this paper, we address the transference of spatial information on highly enantiopure polymers as a critical condition to support the dynamics in a self-organized biogenic system. Previous scenarios have considered almost exclusively the information encoded in sequences as the suitable source of prebiotic information. But the spatial information transference has been poorly understood thus far. We provide the supporting statements which predict that the ordered configuration in a biogenic system should be significantly influenced by spatial information, instead of being exclusively generated by sequences of polymers. This theoretical approach takes into consideration that the properties of mutation and inheritance did not develop before definition of the structures that allow the management of information. Rather, we postulate that the molecular structures to store and transfer information must exist at first, in order to retain particular functional 'meaning', and subsequently, such information can be 'inherited' and eventually modified. Thus, the present contribution follows the theory that life was originated from an unstable prebiotic environment that involves the early spatial information transference based on large chiral asymmetry.


Using data on U.S. Treasury dealer positions from 1990 to 2006, we find evidence of a significant role for dealers in the intertemporal intermediation of new Treasury security supply. Dealers regularly take into inventory a large share of Treasury issuance so that dealer positions increase during auction weeks. These inventory increases are only partially offset in adjacent weeks and are not significantly hedged with futures. Dealers seem to be compensated for the risk associated with these inventory changes by means of price appreciation in the subsequent week.


Background: Premature infants experience alterations in maternal stimulation (including auditory sensory alteration such as talking or singing to the infant in the neonatal intensive care unit) due to admission to the neonatal intensive care unit. Because of their physiological and neurobehavioral immaturity, infants are at an increased risk of delays in reaching feeding milestones (a key developmental milestone), which often need to be achieved before discharge. Purpose: This systematic review evaluated the literature regarding the effect of maternal speech on achievement of feeding milestones in premature infants. Data Sources: A systematic search of CINAHL, PubMed, Web of Science, and Google Scholar from 2010 to 2021. Study Selection: Studies were selected if they examined the effect of maternal voice interventions on premature infants' feeding milestones. Data Extraction: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used. Results: Six studies were identified. This systematic review of the literature on the effects of maternal voice on feeding milestones in premature infants found equivocal results. Implications for Practice: Given the inconsistent results, this systematic review does not support a change in clinical practice. However, encouragement of maternal visits is highly recommended as the additional benefits of the mother's presence may extend beyond exposure to maternal voice. Implications for Research: More research is needed including use of more homogenous samples, application of recommended decibel levels, and utilization of an adequately powered randomized controlled trial to further examine the effects of maternal voice on feeding milestones.


The main objective of this work, was to develop a fresh cheese using buffalo's milk, as the main raw material, in attempt to introduce this proteins rich source in the brazilian's alimentary habits. Several experiments were done to establish the optimum values for fundamental cheesemaking parameters (calcium cloride, rennet and salting time: sodium cloride value), and combinations. Physical and chemical characteristics of the milk and the resulting cheese were described. The cheese's average composition was: fat 21,50%; protein12,68%; dry extract 40,36%; ash 3,13%; moisture 58,77%; with a yield of 29,25%. Sensory analysis showed that the buffalo cheese was within quality standards for flavor intensity, saltness, consistency and bitterness. The general acceptance of the cheeses was satisfactory . The results showed which factors should be considered important, allowing to outline future processes to obtain products of better quality.


Panel unit root and no-cointegration tests that rely on cross-sectional independence of the panel unit experience severe size distortions when this assumption is violated, as has e.g. been shown by Banerjee, Marcellino and Osbat (2004, 2005) via Monte Carlo simulations. Several studies have recently addressed this issue for panel unit root test using a common factor structure to model the cross-sectional dependence, but not much work has been done yet for panel no-cointegration tests. This paper proposes a model for panel no-cointegration using an unobserved common factor structure, following the work on Bai and Ng (2004) for panel unit roots. The model enables us to distinguish two important cases: (i) the case when the non-stationarity in the data is driven by a reduced number of common stochastic trends, and (ii) the case where we have common and idiosyncratic stochastic trends present in the data. We study the asymptotic behavior of some existing, residual-based panel no-cointegration, as suggested by Kao (1999) and Pedroni (1999, 2004). Under the DGP used, the test statistics are no longer asymptotically normal, and convergence occurs at rate T rather than sqrt(N)T as for independent panels. We then examine the properties of residual-based tests for no-cointegration applied to defactored data from which the common factors and individual components have been extracted.


tion from, and have conflicting interests with, the local economy. In this essay, I challenge this assumption and show how the livelihood systems of one community, the Baiga (conventionally regarded as a group of swidden cultivators) of Eastern Central Provinces, was dependent on the complex interconnections between the local and regional economies. The parameters of the local economy were in turn defined by relations of production and exchange that constituted these networks. By overlooking these relationships in their analysis, scholars have often tended to overemphasize the role of practices like shifting cultivation in the study of the identity and material life of these communities. In the process, they have also tended to romanticize the relationship between people and forests. A simplistic connection between culture and ecology, often referred to as 'cultural ecology', is evident in the twentieth century descriptions of Baiga life and livelihood of which Verrier Elwin's The Baiga is a good example. For example, Elwin, as we shall see in this essay, goes out of his way to prove that cultural practices correspond to ecological roles. In the process, he overstresses the importance of the eco-friendly character of bewar (the Baigani


Internet-Drafts are working documents of the Internet Engineering Task Force (IETF), its areas, and its working groups. Note that other groups may also distribute working documents as Internet-Drafts. Internet-Drafts are draft documents valid for a maximum of six months and may be updated, replaced, or obsoleted by other documents at any time. It is inappropriate to use Internet-Drafts as reference material or to cite them other than as "work in progress." Abstract There are a variety of intermediate devices in the Internet today that require application intelligence for their operation. Datagrams pertaining to real-time streaming applications such as SIP and H.323 and peer-to-peer applications such as Napster and NetMeeting cannot be identified by merely examining packet headers. Middleboxes implementing Firewall and Network Address Translator services typically embed application intelligence Srisuresh, et al. within the device for their operation. The document specifies an architecture and framework in which trusted third parties can be delegated to assist the middleboxes to perform their operation without resorting to embedding application intelligence. Doing this will allow a middlebox to continue to provide the services, while keeping the middlebox application agnostic. A principal objective of this document is to enable complex applications through the middleboxes seamlessly using a trusted third party.


The invention provides a phosphorus slag aerated brick. The phosphorus slag aerated brick is prepared from the following raw materials: 20 to 30 weight parts of phosphorus slag, 25 to 30 weight parts of coal ash, 5 to 10 weight parts of cement, 4 to 6 weight parts of modified sepiolite powder, 5 to 10 weight parts of powdered carbon, 5 to 10 weight parts of expanded vermiculite, 5 to 10 weight parts of calcium triple superphosphate powder, 10 to 15 weight parts of lime, 0.1 to 0.3 weight percent of triethanolamine lime, 4 to 5 weight parts of gypsum, 0.02 to 0.08 weight part of aluminum powder, peregal which is 3 to 5 percent based on the weight of the aluminum powder, 0.01 to 0.02 weight part of lauryl sodium sulfate, 2 to 3 weight parts of volcanic rock, 1 to 2 weight parts of lignocellulose, 0.3 to 0.5 weight part of soda ash, 1 to 2 weight parts of white emulsion, 1 to 2 weight parts of hydroxypropyl methyl cellulose sodium, and 1 to 2 weight parts of chitosan. Phosphorus slag is added into the raw materials of the aerated brick, other conventional aids and modified aids are added, and the aerated brick processed by an appropriate process can protect cultivated land, saves energy, reduces consumption, belongs to an environment-friendly building material, is low in cost and high in performance, achieves the cyclic economy effect of changing waste into wealth, and reduces pollution; and the processed aerated brick has the characteristics of light volume weight, high thermal insulation performance, good sound absorption effect and high intensity, and can be used for a non-load bearing brick and a load bearing wall body.


International Carpathian School is a fast-growing volunteer project in Kosiv, Ivano-Frankivsk region, Ukraine, designed as a local centre of non-formal education to address youth adaptation to the globalized world. It intended to overcome the existing gaps in the education of socially conscious youth, finding optimal ways of skill-sharing activities to local communities. Among others, the school is oriented for delivering knowledge, skills and attitudes of the EU best practices in the field of municipal solid waste management (MSWM). In a broader meaning, the Carpathian School Agenda serves for the environmental protection of the vulnerable mountain landscapes to meet the Sustainable Development Goals Ukraine-2030 (hereof and after SDG), entered in force by the Decree of the President of Ukraine in order to ensure the national interests of Ukraine in relation to sustainable economic development [1]. The School activity is aligned with both SDG-4 "Quality education" and SDG-11 "Sustainable cities and communities". It has an interdisciplinary approach to learning where academic concepts of geoscience are coupled with real-world lessons. Carpathian Winter School hosted researches from Ukraine, Georgia and Armenia together with five educational entities from Baltic Sea Region (BSR). Scholars were exposed to a cross-cultural experience that facilitates connections between the classroom and the world around them. Simultaneously, the School is providing a prospect to local scientists in maintaining professional links with their foreign colleagues and obtaining hands-on scientific information on MSWM. Having a central geographical position and well-developed informal tuition activities, the Carpathian School may have a good chance to become a placement for students' mobility, people-to-people contacts and promoting youth employability that is coherent with The Eastern Partnership (EaP) policy [2]. The educational project of the Swedish Institute LASUWAMA [3], which was considered at the Carpathian Winter School, combined researchers from Ukraine, Georgia and Armenia. Representatives of EU universities, involved in the development of educational programs, provided the relevant knowledge and skills, needed to students for gaining an in-depth understanding of the sustainable development concept [4], including, inter alia, access to further vocational training in EU countries


The response to the increase in average farm size in England in recent decades, particularly by those with a concern for the rural landscape, has been to pose the question: how much bigger can farms become?

This paper contributes to the discussion of this question by examining how different combinations of land, labour and capital and/or improvements in these resources can lead to the formation of large farms. Two models are constructed representing different cropping systems and Linear Programming is employed to test for the effect of variation in the quantity and characteristics of labour and machinery. The data used in the models were derived from random sampling among the large, arable farms of the South and East of England.

'Big scale farming in England still remains to be tried'. (Orwin, 1930).


Indazolone derivatives exhibit a wide range of biological and pharmaceutical properties. We report a rapid and efficient approach to provide structurally diverse 2-N-substituted indazolones via photochemical cyclization in aqueous media at room temperature. This straightforward protocol is halide compatible for the synthesis of halogenated indazolones bearing a broad scope of substrates, which suggests a new avenue of great importance to medicinal chemistry.


This article explores the regional disparities in water supply coverage in Pakistan in the context of intraregional development patterns. We applied the Gini index, Esteban and Ray index, and Moran's I to measure regional development patterns in terms of inequality, polarization, and spatial concentration and build an integrated framework combining them with other widely accepted factors to understand regional differences in water coverage quantitatively. Our results show that improved water (tap and pump water) is more widely supplied in Pakistan with lower inequality but higher spatial concentration than tap water supply coverage, although the patterns differ by urban–rural divisions and provinces. Western regions with smaller populations tend to have higher tap water coverage, and eastern regions with large populations are more covered by improved water. The regression models show various mechanisms of improved water and tap water coverage. Both are related to local economic conditions but tap water coverage is more related to local environmental conditions, and improved water is more related to local demographic conditions. Strong and dense population centers decrease improved water coverage but promote tap water coverage. Urban planners and policymakers should address polycentric regional development to fulfill various development targets and improve regional equity of drinking water coverage in terms of accessibility, availability, and quality.


This paper gives a short recapitulation of the constraints for forward and futures prices under the condition that no risk-free profits can be achieved through arbitrage activities.


Acid-catalysed deuteriodeprotonation rates are recorded for uracil, 1,3-dimethyluracil, 2,6-dimethoxypyridine, 4-dimethylaminopyridine, and cinnoline. The rates are extrapolated to give standard rate constants at 100 °C and H0 0 and also at 25 °C 75% H2SO4. Use of the latter conditions, i.e. those previously selected to determine standard nitration rates, give less scatter in a direct comparison with the standard nitration rates. Although the absence of a unique linear relationship is clearly demonstrated, the use of identical standard conditions discloses very good partial linear correlations for substrates of closely related structure.


This article supports the practice of measuring system design by providing information on the ways to improve the development and operation through the adoption of a systems thinking approach. This helps give a sharper focus to design issues and targets the wider responsibilities of the design team. Covered here are the elements of systems engineering and systems thinking; holistic detail design; engineering reductionism and soft systems methods; systems of systems; and the application of systems thinking.


Inorganic chemistry is an important basic course of pharmacology at medical universities.It has been a goal for chemical teachers at medical universities to pursue to produce high-quality pharmacological professionals.To inspire students' interest and enhance teaching quality,we reformed the teaching content,methods and assessment of inorganic chemistry experiment course,which has achieved good results.


Resource-constrained devices such as sensors, industrial controllers, analyzers etc., mostly contain limited computational capacity and memory. They are largely deployed in all industries and have been generating a huge amount of data. This data is sent to the cloud servers where various Machine Learning (ML) algorithms are applied to perform the analysis or prediction as per the application. In this process, communication requires bandwidth and time. Since the data is sent into the network, the privacy of the data is not guaranteed. Cloud servers consume a huge amount of power. To reduce these cost factors, the machine learning models are compressed and optimized such that they can fit and run in small footprint devices. The Federated Learning (FL) approach at the edge device level promises to address the data privacy and bandwidth related issues. Since it is a decentralized learning method across a set of devices, the performance of the model also improves. This paper describes and evaluates the machine learning algorithms with various compression methods suitable for resource-constrained IIoT devices and federated learning approach, particularly for time series data applications. Simulation results show that FastGRNN algorithm gives the least model size compared to the traditional RNN algorithms for time series.


The complete quantum metric of a parametrized quantum system has a real part (usually known as the Provost-Vallee metric) and a symplectic imaginary part (known as the Berry curvature). In this paper, we first investigate the relation between the Riemann curvature tensor of the space described by the metric, and the Berry curvature, by explicit parallel transport of a vector in Hilbert space. Subsequently, we write a generating function from which the complex metric, as well as higher order geometric tensors (affine connection, Riemann curvature tensor) can be obtained in terms of gauge invariant cumulants. The generating function explicitly relates the quantities which characterize the geometry of the parameter space to quantum fluctuations. We also show that for a mixed quantum-classical system both real and imaginary parts of the quantum metric contribute to the dynamics, if the mass tensor is Hermitian. A many operator generalization of the uncertainty principle results from taking the determinant of the complex quantum metric. We also calculate the quantum metric for a number of Lie group coherent states, including several representations of the $SU(1,1)$ group. In our examples non-trivial complex geometry results for generalized coherent states. A pair of oscillator states corresponding to the $SU(1,1)$ group gives a double series for its spectrum. The two minimal uncertainty coherent states show trivial geometry, but, again, for generalized coherent states non-trivial geometry results.


The article discusses the possibility of modern smartphones sensors usage during vehicles road tests performing in educational process of the Moscow Automobile and Road Construction State Technical University (MADI) in teaching students of evening classes of specialty "Automobiles and automobile industry".