1 SUMMARY One of the fundamental questions in health economics is the relationship between two types of human capitalhealth and education. A persistent research problem, though, is measuring a causal effect, because health is endogenous in models that predict educational attainment. We use genetic information as instrumental variables for obesity and substance use. We analyze data from the National Longitudinal Study of Adolescent Health (Add Health) because a subset of respondents contributed DNA samples. Six genes identified from the DNA samples were originally chosen specifically because they are known to be related to dopamine or serotonin, neurotransmitters related to satiation, obesity, substance abuse, and other behaviors. Four additional genes were recently added to the public data set. The genetic information provides strong instrumental variables, with large incremental effects. Several genes predict changes in BMI of more than three BMI units, in number of cigarettes smoked by more than two per day, and in the probability of using illegal drugs by more than 30 percentage points. While simple cross-sectional results show a strong negative effect of smoking during adolescence on eventual high school education, two-stage least squares results show no statistically significant effect. As predicted in the conceptual framework, the endogeneity bias is negative. This result is consistent with a story of omitted variables such as the discount rate. Acknowledgements The authors have no financial or personal relationships between themselves and others that might bias their work.


AbstractThe structure of the gelatin-palladium(u) complexes formed under a variety of conditions was studied by measuring CD and absorption spectra and comparing them with those of simple peptide complexes. The complex is considered to be tetragonal and tetracoordinate. In the acid pH region the formation of two types of complexes in which palladium(n) is bound by the carboxylate group is proposed, depending on the pH and gelatin concentration. The formation of complexes in which palladium(n) is bound by each of the imidazole and amino groups is shown above around pH 4.5. In the alkaline pH region all of the carboxyl, imidazole and amino groups are involved in complexing, and palladium(u) is presumably coordinated by three peptide nitrogen donor atoms in addition to the ionizable side-group. In both acid and alkaline pH regions an additional band is observed near 260 nm in the circular dichroism spectrum, which is ascribed to the complex with one imidazole nitrogen and three peptide nitrogen donor atoms.


Background and purpose Previous studies have stimulated debates on low-dose alteplase administration in acute ischemic stroke (AIS) among the Asian population. We sought to evaluate the safety and efficacy of low-dose alteplase in Chinese patients with AIS using a real-world registry. Methods We analyzed data from the Shanghai Stroke Service System. Patients receiving alteplase intravenous thrombolysis within 4.5 hours were included. These patients were divided into the low-dose alteplase group (0.55–0.65 mg/kg) and the standard-dose alteplase group (0.85–0.95 mg/kg). Baseline imbalances were adjusted by using the propensity score matching. The primary outcome was mortality or disability, which was defined as the modified Rankin scale (mRS) score ranging from 2 to 6 at discharge. The secondary outcomes were in-hospital mortality, symptomatic intracranial hemorrhage (sICH) and functional independence (mRS score 0–2). Results From January 2019 to December 2020, a total of 1,334 patients were enrolled and 368 (27.6%) were treated with low-dose alteplase. The median age of the patients was 71 years, and 38.8% were female. Our study showed that the low-dose group had significantly higher rates of death or disability (adjusted odds ratio (aOR) = 1.49, 95% confidence interval (CI) [1.12, 1.98]) and less functional independence (aOR = 0.71, 95%CI [0.52, 0.97]) than the standard-dose group. There was no significant difference in sICH or in-hospital mortality between the standard-dose and low-dose alteplase groups. Conclusions Low-dose alteplase was related to a poor functional outcome without lowering the risk of sICH, compared with standard-dose alteplase for AIS patients in China.


Written by the author of "The Pumpkin Eater", this is a novel about journalists who go to Canada for a public relations exercise, an opportunity to write about its culture and to enjoy an expenses-paid spree. For Muriel Rowbridge it is her first assignment since having a breast removed.


Abstract There are two major ways in which Buddhist logic is developed. The first one is represented by Nāgārjuna-Candrakῑrti tradition through the use of dialectics and the second way of development is found in the works of Diṅnāga and Dharmakῑrti through the use of hetu (probans). This second way of logic has further been developed by the works of Jinendrabuddhi and Ratnakῑrti. The paper is an attempt to show the historical development of epistemic logic as developed by the Buddhist philosophers and their relevance for our time.


The purpose of this study is to examine abuse of dominant position and its influence on job engagement, as well as the moderating effects of LMX between abuse of dominant position and engagement. To draw measurement scales, in-depth-interview and questionnaire surveys were conducted to investigate cases of guests' abuse of dominant position with hotel employees. Results of the investigations were categorized by expert group of hotel industry. A pilot test was conducted for drawing final measurement scales with hotel employees. Thirteen scales were drawn with low frequency scales eliminated after the pilot survey. Data was collected from 372 employees at five star hotels in Seoul. This study applied exploratory factor analysis, reliability analysis, multiple regression analysis, Chow-test and Z-test. The findings of this study were as follows: First, abuse of dominant position of hotel guests against hotel policy and emotion and physical of hotel employees were negatively influenced job engagement. Second, LMX has moderating effects between abuse of dominant position of hotel guest and job engagement. The results of this study suggest policy management plans, empowerment for complaints handling, and the enhancement of LMX.


A great number of metal and semiconductor photocathodes, which are of high practical importance for photoinjector applications, closely follow the 1/3 gradient Dowell-Schmerge (DS) law describing the spectral dependence of the mean transverse energy ($MTE$), $viz.$ $MTE$ as a function of the incident laser photon energy. However, some (rare) semiconductor photocathodes show $MTE$ trends that are significantly different. For example, spectral $MTE$ measurements on PbTe, BaLaSnO or Hf/HfO$_2$ have clearly demonstrated trends that can differ from DS law being non-monotonic, slower growing, or displaying constant $MTE$ versus laser photon energy. We have discovered that $n$-type ultra-nano-crystalline diamond (UNCD) and single crystal diamond are anti-DS photocathodes in that their $MTE$ decreases with the incident photon energy. It was previously established that UNCD is a highly emissive material in the near UV such that quantum efficiency ($QE$) grows with the laser photon energy. The unique and novel combination of high increasing $QE$ and low decreasing $MTE$ of UNCD may pave the way to desired high brightness electron beams, through operation well above its work function which fundamentally differs from 'Boltzmann tail' operation near the photoemission threshold. One other remarkable result followed: As UNCD is a $sp^2$ grain boundary diluted $sp^3$ diamond matrix, control over grain boundary/grain engineering in the material's synthesis allowed for the production of different kinds of UNCD. The resultant tuning of the $sp^3$-to-$sp^2$ ratio in different UNCD photocathodes allowed for switching between canonical +1/3 DS and approximate --1/3 gradient 'anti-DS' behavior.


µ-Oxo-bis(chlorotriphenylbismuth) is an effective reagent for the oxidation of the hydroxy group under exceptionally mild conditions; it is especially applicable to allylic alcohols.


An important advantage for using genetic transformation to improve perennial fruit trees is that a single horticultural trait can be altered, without significantly affecting the phenotype of the cultivar. Embryogenic avocado cultures have been transformed with different gene constructs in order to address different breeding objectives. Avocado is being transformed with genes encoding for different antimicrobial proteins, including chitinase, glucanase, the antifungal protein (AFP) and magainin, and the first greenhouse planting of transgenic plants containing the gene for AFP has been established. As part of a strategy for controlling avocado sunblotch disease, embryogenic cultures have been transformed with the pac1 ribonuclease gene from yeast. In order to control fruit ripening and extend the shelf life of avocado fruit, embryogenic cultures have been transformed with the gene for SAM hydrolase, a bacterial gene that mediates the breakdown of S-adenosylmethionine (SAM), a precursor of ethylene.


Phase Equilibrium Investigations of Planetary MaterialsPrincipal Investigator: T.L. Grove54-1220Department of Earth, Atmospheric and Planetary SciencesMassachusetts Institute of TechnologyCambridge, MA 02139Period covered by report: July 1, 1993 - June 30, 1997This grant provided funds to carry out experimental studies designed to illuminate theconditions of melting and chemical differentiation that has occurred in planetary interiors.Studies focused on the conditions of mare basalt generation in the moon's interior and onprocesses that led to core formation in the Shergottite Parent Body (Mars). Studies alsoexamined physical processes that could lead to the segregation of metal-rich sulfide meltsin an olivine-rich solid matrix. The major results of each paper are discussed below andcopies of the papers are attached as Appendix I.A paper with Tom Wagner was published in Geochimica Cosmochimica Acta.Experiments reported in this paper measured the dissolution rate of ilmenite in a broadspectrum of mare basalt and lunar ultramafic glass compositions. The dissolution rateswere used to assess the efficiency of assimilation mechanisms that produce high-Tiultramafic glasses by assimilating pyroxene + ilmenite magma ocean cumulates. Phaseequilibrium experiments were also performed on an Apollo 14 Black Glass to 2.2 GPa,and used to model the thermal energy budget of assimilation.A paper with Glenn Gaetani was also published in Geochimica CosmochimicaActa. The partitioning behavior of V, Cr, Mn, Co, Ni, Cu and W among coexisting sulfidemelt, silicate melt, and olivine was investigated. Experiments were performed at 1 atmpressure, 1350°C, with the fugacities of oxygen and sulfur controlled by mixing CO2, CO,and SO2 gases. One result of this study was the calibration of the functional relationbetween sulfide melt/silicate melt partitioning and fo2 and fs2. The experiments also usedthe abundance of transition series elements to provide constraints on the mass andcomposition of the core of the Shergottite Parent body (Mars).An abstract with Glenn Gaetani published in Lunar and Planetary Science XXVIIexplores the potential controls of variations of


Abstract Lately there had been a huge push in our profession toward the use to use the Directed Lie Comparison question (DLC). The truth verification field is divided into "pro and con" towards this idea, like many things in life. This article will research whether this "new fashion" is really the correct way or the easy or lazy way to conduct psychophysiological truth verification examinations, as well as make comparisons between the advantages and disadvantages between the DLC and the Probable Lie Comparison question (PLC).


But it is not limited to, a useful joint mechanism with respect to various purposes, including remote control of appliances, such as surgical or instrument for diagnostic or tool, link systems, and components thereof are provided. Link system is provided with a link, while allowing for pivoting movement between the link, it can be transmitted between the at least two adjacent link the torque. Mechanism for preventing the operation of the unwanted side with respect to each other of the link is also provided.


INTRODUCTION The value of zooplankton as an indicator of ecological processes arises from its position in various food webs. Zooplankton acts as a middle point between top-down (fishes) and bottom-up (phytoplankton) regulators (Jeppesen et al., 2011). Thereby, zooplankton indirectly indicates trophic interactions between phytoplankton/bacterioplankton and zooplankton as well as zooplankton and fishes, hence, eutrophication as well as fish predation on zooplankton (Haberman, 1996). Direct predation pressure from fish can significantly impact on zooplankton communities. For example, predation-induced mortality leads to a high percentage of overall mortality in copepods (Hirst and Kiorboe, 2002; Tang et al., 2006; Martinez et al., 2014). Larger individuals of zooplankton are normally consumed in case of high rates of fish predation, which leads into a situation where domination within zooplankton communities is given to smaller individuals (Haberman, 1996; Brucet et al., 2010; Jeppesen et al., 2011). In addition to the size of zooplankton, top-down predation pressure is also affected by the morphology of various life history stages of zooplankton (Brooks and Dodson, 1965; Otto et al., 2014). A common assumption is that marine zooplankton is bottom-up controlled. Thus, it could be used as an indicator of climate change effects in the open ocean where anthropogenic impact on top of the food chain is considered to be negligible (Adrian et al., 2006; Barton et al., 2013; Daewel et al., 2014). Nevertheless, recently species on lower trophic levels have shown cascading effects in various marine ecosystems due to the overfishing of top-down predators (Casini et al., 2008, 2014). Various studies have focused on long-term dynamics of zooplankton in relation to hydro-climatic conditions in the adjacent sea (Viitasalo et al., 1995; Mollmann et al., 2000, 2008; Kotta et al., 2009). It is common in aquatic ecosystems that hierarchic response takes place along trophic levels, i.e. the intensity of response to eutrophication can vary among trophic levels (Hsieh et al., 2011; Lewandowska et al., 2014). Surprisingly, mesozooplankton has not been included into the European Water Framework Directive (WFD) as a quality element. The importance of mesozooplankton in terms of ecological environmental assessment has been demonstrated in rivers and lakes, and the necessity of including mesozooplankton in the WFD has been outlined (Jeppesen et al., 2011). However, mesozooplankton is included into the EU Marine Strategy Framework Directive (MSFD). On the basis of work carried out by the MSFD HELCOM zooplankton working group, a core indicator of food web structure based on mesozooplankton, i.e. the average size or weight of a zooplankter, was proposed by Gorokhova et al. (2013a). The indicator is also supported by total values of zooplankton abundance and biomass. Thus, the measure captures both zooplankton community structure (by mean weight) and the stock size (by biomass or abundance). In the current study we analysed the use of this indicator of good environmental status in the northeastern Gulf of Riga based on zooplankton data collected mainly from Parnu Bay. The effect of zooplankton as a food source affecting fish growth was evaluated. Seasonal and interannual variation of total abundance and biomass of zooplankton together with mean weight of a zooplankter was analysed based on both seasonal and long-term data. MATERIAL AND METHODS Field data were collected from the northeastern Gulf of Riga, mainly from Parnu Bay, between 1957 and 2013. In total 6746 quantitative samples of mesozooplankton were used (of these 3067 were collected from June to August). Zooplankton sampling and analysis followed the HELCOM recommendations (1988). Samples were collected with a Juday type plankton net (mouth opening 0.1 [m.sup.2]; mesh size 90 [micro]m) with vertical hauls from the seabed up to the surface. …


A hypothesis is presented which states that persons with the genetic disorders xeroderma pigmentosum and ataxia-telangiectasia, manifested by a deficiency of DNA repair, develop cutaneous tumors due to the elimination of reticuloendothelial system cells (Langerhans cells) in the skin, and the subsequent loss of control of epidermal cellular elements.


Abstract The aim of the research is to study the effect of a two-stage heat treatment process of two iron based Ni-Co-Mo alloys on microstructure, micro-hardness and residual stress distribution. The laser cladding with multi-jet powder injection was used to deposit different alloys on the 12 % nickel maraging tool steel specimens 1.2799 (SIST EN 10027-2) to study the effect on the material's properties. In Ni-Co-Mo-1 austenite alloy, the precipitation hardening had no effect on hardness even after a prolonged overaging for 16 hours at 720 C. The second alloy Ni-Co-Mo-2 has a chemical composition similar to the maraging steel substrate. After 3 hours of precipitation hardening at 550 C, the alloy hardness increased to the level of base material. The residual stresses were measured using the hole drilling method. The residual stress profiles into the depth show predominantly tensile residual stresses in the Ni-Co-Mo-1 deposit and compressive residual stresses in the Ni-Co-Mo-2 deposit. The results indicate the importance of the chemical composition on microstructure, hardness and residual stresses prior and after heat treatment as well as of the quality of the deposited material on the maraging steel.


The author addresses a range of issues connected with the classification, for mapping purposes, of marine life of the continental shelves. Based on a classification according to general life form and species affiliation, a system of map symbols is elaborated and various issues associated with its use on maps are investigated. These include how to factor in the differential mobilities of pelagic and benthic species when designing symbols depicting boundaries of plant and animal communities in the two different environments and how to achieve a balance between the representation of species diversity and of species dominance (overall biomass). Translated by Jay K. Mitchell, PlanEcon, Inc., Washington, DC 20005 from: Geodeziya i kartografiya, 1989, No. 9, pp. 25–29.


The textbook is designed to help first-year students in the first semester to complete coursework on descriptive geometry, consisting of a number of traditional tasks. It is considered together with the textbooks "Collection of problems on descriptive geometry" and "Descriptive geometry: assignments for term papers".
For students of higher educational institutions studying in the areas of "Architecture", "Design". It is of interest to all students of descriptive geometry.


Human rights are those rights which a person can enjoy because of their birth as a human being. In other words, the expression 'human rights' is being used to denote those rights and freedoms which belong to every individual irrespective of their nationality and citizenship. In the European Union (hereinafter referred as EU) the European Convention for the Protection of Human Rights and Fundamental Freedoms (ECHR, hereinafter mentioned as the 'Convention') was a momentous agreement designed for the purpose of achieving the mission i.e. Protecting the basic human rights in its member countries. It made its member countries answerable to the European Commission (hereinafter referred as EC) in so far as the context of human rights protection is concerned therein. Likewise, the Convention has empowered the European Court of Human Rights with regard to adjudication of such matters on the basis of complaints from individuals of the member countries. Amongst the countries that have ratified the Convention, the United Kingdom (hereinafter referred as UK) comes in the first row. In so far as the legal framework pertaining to codification of human rights in United Kingdom is concerned, the most essential legal document is the Human Rights Act, (HRA, hereinafter referred as the 'Act') 1998. It came into force therein in the month of October, 2000. The prime objective of giving birth to the above noted legislation was to officially insert the ECHR provisions into the municipal law of UK. Enactment of this particular legislation has opened the door in front of UK people to take their cases into a UK Court in case their enjoyment of human rights gets questioned. Earlier, they had to take such complaints to the ECHR. This essay is intended to look into and analyze the role of Courts in practical manifestation of the Act in UK. It is also going to evaluate to what extent Courts have become successful in achieving the noted mission in so far as the up to date phenomena are concerned. However, before taking entry into the evaluation part, it is essential to highlight the objects and purpose of the Act so as to make the entire analysis well arranged.


As an important step in the technical reformation of tar refining system of Coking Plant of Xuan Steel,the process of continuous washing and carbon dioxide decomposition overcomes the defects of the original intermittent washing system: low efficiency and reaction not sufficient,can get better economic and social profit.


Part 1 Making healthy babies: turning good odds into best odds what to eat when you're expecting the best odds for a comfortable pregnancy the best odds for everyone what to eat when you're nursing eating for the next baby. Part 2 Getting practical: preparing for the best-odds diet what's safe to eat - and what's not. Part 3 Best-odds recipes: cereals, eggs and griddle cakes, breads and muffins, soups, vegetarian main dishes, main courses, vegetable side dishes, salad suggestions and dressing recipes, puddings and other desserts, pies, biscuits, cakes, frozen desserts, party foods, drinks, quick fixes.


Because of the redundancy of ribosomal RNA cistrons and in analogy with a few known special cases, one may postulate that a few "master genes" for rRNA direct the synthesis of multiple copies of themselves per cell cycle. We have shown that in Chinese hamster cells rRNA cistrons duplicate like the bulk of DNA, once in a cell cycle. The time during the S-phase at which rRNA genes duplicate has also been determined by means of RNA-DNA hybridization studies.

The time of duplication of rRNA genes occurs between t= 1.5 and t= 3.0 hours from the beginning of the S-phase.


Relying largely on Winnicott's ideas about transitional phenomena and transitional objects, this paper reviews the ways in which group experience can be psychologically meaningful, even necessary, for many young people. A distinction is made between healthy and pathological, or antisocial uses of the group, and some of the possible dynamics determining involvement with antisocial groups are discussed. Study of ways in which groups can be organized that will assist youth to work through developmental issues in a pro-social fashion is strongly recommended.


Work principle of contrary electric current protection of aluminium electric is discussed in this pa-per,fixing contrary current protection can reduce economy lose of electric current change system.


Abstract: Advances in nanotechnology will lead to improvements in capabilities across a spectrum of applications. The uses of polymer nanocomposites in aerospace structures have had a significant effect on aerospace design and applications, primarily by providing safer, faster and eventually cheaper transportation in the future. This chapter reviews key properties of polymer nanocomposites for potential aerospace applications. In particular, the chapter discusses mechanical, field emission, thermal, electrical and optical properties of polymer nanocomposites for aerospace needs.


Eighty-three subjects participated in a study of the relation between fantasy styles and hypnotic dreaming. As hypothesized, subjects who reported that their daydreams revolved around fearful, guilt-ridden, and achievement-based (Guilt-fear-of-failure, GFF) fantasies, were more likely to report negative emotion and anxiety in their dreams. However, positive-constructive (PC) fantasy and poor attentional control (PAC) fantasy styles were unrelated to affect expressed in subjects' hypnotic dreams. We also found that fantasy proneness was correlated with both the PC and GFF fantasy styles. Copyright © 1996 British Society of Experimental and Clinical Hypnosis


Cobalt aluminate () is a highly stable pigment with excellent resistance to light, weather, etc., which has resulted in widespread use as a ceramic pigment. Due to the unique optical characteristics, is generally used as a coloring agent to decorate porcelain products, glass, paints and plastics. Here, pigments were synthesized by polymerized complex method and solid state reaction. Then pigment were grinded using the attrition milling with 1 mm size zirconia ball for 3 hours. The attrition milling process was performed at the constant speed of 800 rpm and ball to powder weight ratio (BPR) was 100 : 1. The characteristics of synthesized pigment were analyzed by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), particle size analyser (PSA) and CIE . The XRD patterns of show single phase spinel structure. The particle size of measured by FE-SEM, TEM and PSA analysis was in the range of 100~200 nm. The blue color of obtained pigments could be confirmed through CIE measurement.


series of Ca1-xSrxS:Ce phosphors were synthesized by solid-state reactions. The Ca1-xSrxS:Ce phosphors have a strong absorption in region from 430 nm to 470 nm. The emission peaks of CaS:Ce are located at 510 nm and 570 nm. The partial replacement of Ca by Sr in Ca1-xSrxS:Ce causes a blue shift of emission wavelengths. The Ca1-xSrxS:Ce can be used as bluish green and yellow emitting phosphors for white light emitting diodes (LEDs) pumped by the blue LED. We reported the optical properties of Ca1-xSrxS:Ce phosphors for application in phosphor converted white LEDs.


Through Moses, Zora Neale Hurston alludes to another figure seeking to lead his recalcitrant people to the Promised Land—Alain Locke. Like Locke, Hurston's Moses is a cultural-nationalist, values self-reliance, and levels authoritative judgments. The benefit of reading Moses, Man of the Mountain(1939) in the context of Locke's criticism of Hurston's work is that it allows us to see how Hurston is engaged not only in critiquing authoritarian politics, but also in interrogating the politics of aesthetic uplift. Mosesstands as an alternative model to Locke's conception of how to incorporate folk culture into fiction. Hurston rejects the authoritarian strand of Locke's cultural politics by valuing folk culture on its own terms, rather than treating it as a mere source of inspiration for true art. Hurston participates in what she perceives to be an ongoing oral and literary tradition, instead of seeking to transform folk culture into something more palatable for highbrow audiences.


PurposeThe purpose of this paper is to investigate the links among different forms of religiosity, family cohesion and ethical leadership in family firms operating in Turkey.Design/methodology/approachThe study was conducted with 210 respondents working in 51 family firms operating in Istanbul. Data regarding ethical leadership perceptions were collected separately from employees (non-family member) and managers (family member), and responses were matched in firm level to investigate the relations between variables calculated separately as perceptions of managers and employees. Confirmatory factor analysis and reliability statistics were used for ascertaining the dimensionality and factor structures of the constructs. Correlation analysis, structural equation modeling and bootstrapping method were used for investigating the relationships among variables.FindingsResults of the study demonstrated that family cohesion, intrinsic religiosity and spiritual well-being-oriented religiosity were positively, while secular religiosity was negatively related with ethical leadership levels rated by family member managers. Although none of these variables showed significant correlations with ethical leadership perceptions of non-family member employees, ethical leadership perceptions of the family managers and ethical leadership perceptions of employees were positively correlated, and intrinsic religiosity and spiritual well-being-oriented religiosity had significant indirect effects on ethical leadership perceptions of employees.Originality/valueGiven the lack of studies addressing the links between different forms of religiosity with ethical leadership especially in the Turkish context and the gap regarding research designs analyzing these relationships from the perspectives of managers and employees, the study provides important contributions.


Examines the relationship between the Sexual Offences Act 2003 and the Tyrrell principle. Discusses the origins and scope of the Tyrrell principle that a victim can be guilty of participation in the offence unless the law is designed for the protection of the victim. Considers whether the Act contains a discernible policy of protected interests or persons through a survey of the offences created and the age brackets for offenders and victims.


Purpose - Consumers before making a purchase will do a lot of evaluation by looking at the considerations that exist because there are indeed many factors that must be considered by consumers, so that the products purchased are really in accordance with their wants and needs.  Because there are many factors that influence consumer purchasing decisions, including relationship marketing, influencer marketing and features.  The formulation of the problem and the purpose of this research  is to find out how the influence of relationship marketing, influencer marketing and features on purchasing decisions.
Methodology – The location of this research was in Badung Regency and the sample used was 95 respondents. Research method used is quantitative. In this study the data analysis technique used is the Classical Assumption, Multiple Linear Regression, Coefficient of Determination, t test and F test
Findings - Based on the results of the study, it can be seen that  relationship marketing has a significant positive influence on purchasing decisions, influencer marketing  has a significant positive influence on purchasing decisions, features has a significant positive influence on purchasing decisions and simultaneously relationship marketing   , influencer marketing  and features has a positive and significant influence on purchasing decisions. The magnitude of the influence of the independent variable on purchasing decisions is 53%.
Originality – Application of relationship marketing, influencer marketing, and features on zalora e-commerce to purchasing decisions.


This paper analyzes a new configuration of a recently proposed "springless" vibration energy harvester. In this study, the harvester is positioned so that its oscillations are aligned vertically acting against gravity. The MPG response is investigated experimentally. Test results show that the VEH behaves as a softening nonlinear oscillator even for small excitations. A mathematical model of the underlying impact oscillator is also derived and its parameters are estimated.Copyright © 2011 by ASME


My first job was at the National Electrical Metrology Laboratory of Uruguay, more than thirty years ago. That was really a privilege because I had just finished my first year in the university, and I had the chance to learn from both worlds, the academic and the practical world of electrical measurement. At that time, it was not easy to acquire sophisticated and precise instruments, so from time to time we had to develop our own instruments or devices. It was very interesting to try to solve real problems at work with the tools we were taught in the university. Most of the time, we had to learn independently. We tried new techniques in the field and questioned each result we obtained. I was fascinated by the mysteries of measurements.


July 2020 1 Andrea Frustaci, MD Nicola Galea, MD Romina Verardo, PhD Marco Francone, MD Maria Alfarano, MD Matteo Antonio Russo, MD Cristina Chimenti, MD, PhD Coexistence of different biologically divergent myocardial entities is rare and of difficult recognition. Cardiac imaging can raise the suspicion of the unusual structural combination and solicit endomyocardial biopsy for confirmation. A 59-year old man known to be affected from age 30 years by a mildly symptomatic hypertrophic cardiomyopathy (HCM) was admitted because of recurrent long-lasting (3 months) fever. At admission, all microbiological investigations failed to identify an infectious agent. Eventually serological and hematologic studies diagnosed a monoclonal gammopathy paralleled by a pathological increase of bone marrow plasma cells >10%. Physical examination was unremarkable. Electrocardiogram was characterized by sinus rhythm 68 beats/min with elevated QRS voltages and inverted T wave in D1, AVL, and V6 leads suggesting left ventricular (LV) hypertrophy (Figure 1A). Two-dimensional electrocardiogram showed severe thickening of LV wall with maximal thickness of 21 mm located in the interventricular septum. Cine-magnetic resonance images showed a severe LV hypertrophy (maximal wall thickness of 21 mm at basal septum), with reduced systolic function (LV ejection fraction: 49%), myocardial noncompaction at midapical segments, with multiple deep crypts at the antero-septal wall (Movies I and II in the Data Supplement). An increase of global extracellular volume reflects diffuse interstitial fibrosis, more pronounced in the hypertrophic segments and subendocardial layers. Late gadolinium-enhanced images relieved a diffuse enhancement of the septum, anterior and inferior walls of the left ventricle suggesting extensive amyloid infiltration (Figure 2). Due to clinical manifestation of fever with monoclonal gammopathy and to cardiac magnetic resonance findings raising the suspicion of cardiac amyloid overlapping HCM, the patient underwent cardiac catheterization with coronary, LV angiography, and endomyocardial biopsy. Coronary arteries were normal. LV angiography showed the presence of transmural crypts (Figure 1B) associated with LV myocardial noncompaction. At histology, severely hypertrophied disarrayed cardiomyocytes were fragmented in short runs by interstitial and replacement fibrosis (Figure 1C), suggesting a sarcomeric HCM. The endocardium was frequently interrupted by deep unendothelialized channels denoting LV myocardial noncompaction (Figure 1D). Paraffin sections were tested with immunohistochemistry for transthyretin, apolipoprotein 1 and 2, serum amyloid A, and Kappa and lambda light chains. Strong positivity for deposition of kappa light chain was documented on the interstitium and intramural vessel wall (Figure 1E). At ultrastructural examination, the interstitial space was focally widened by both connective and amyloid fibrils (Figure 1F). © 2020 American Heart Association, Inc. CARDIOVASCULAR IMAGES


Objectives
 The COVID-19 pandemic has wreaked havoc in many settings, including early care and education (ECE) programs. This study describes challenges, supports, and lessons learned from the impact of COVID-19 on efforts to promote nutrition and quality care at ECE programs.

 Methods
 A mixed-methods study of 4 states was conducted. Stakeholders from 22 organizations associated with the Child and Adult Care Food Program (CACFP), representatives of 17 CACFP sponsor organizations, and 40 center-based ECE program directors were interviewed; 100 ECE directors completed surveys.

 Results
 Key challenges included difficulty keeping up with continuous changes and inconsistent COVID-19 requirements across federal, state, and local regulatory agencies. ECE directors reported shortages of personal protective equipment, food, and supplies early in the pandemic. To protect their staff, children and families, directors took proactive measures including stopping family-style meals, switching to single use utensils or individually-packaged meals, conducting daily temperature checks, and installing sanitation stations at building entrances. Despite these efforts, many directors reported staff shortages, low enrollment, and center closures due to state mandates and positive cases on-site. Supports highlighted by stakeholders included the emergency relief funds from state agencies (57%), additional funding from other organizations (46%), access to information from state agencies, sponsors, and community organizations about where to find personal protective equipment (30%), and the CACFP waivers from the U.S. Department of Agriculture (16%). Lessons learned included the need to continue to prioritize federal/state funding to support ECE, provide enhanced internet access to rural programs, and make aspects of the CACFP waivers permanent.

 Conclusions
 The pandemic has challenged the ECE system, but has also drawn attention to the essential role of ECE in child nutrition and education. This study highlights potential opportunities for new policies to enhance efforts to promote child nutrition and quality care at ECE.

 Funding Sources
 Healthy Eating Research, a national program of the Robert Wood Johnson Foundation (RWJF); and the School of Public Health at Indiana University Bloomington.


This paper investigates the problem of testing that stock returns are uncorrelated without assuming statistical independence. This paper presents a generalized Box-Pierce Q statistics, denoted by Q*, which has an asymptotic chi-square distribution when the times series is uncorrelated provided it is a martingale difference sequence.


A dynamic factor model and an autor egress ive model for factor scores are developed for surface water-quality data. The combined model permits the state-space formulation of the system and the use of the Kalman filter for forecasting the time series of water quality constituents. The calibrated model using the monthly water quality data for ten constituents at Station 214 of the Neosho River is used for forecasting the time series of water quality constituents.


On an hypothesis that intermediate values of individual differences in arousal or stimulation-seeking would be associated with best performance in timed tests of originality and fluency, undergraduate volunteers were administered the Unusual Questions Test and stratified on the basis of two stimulation-seeking measures into high, intermediate and low stimulation-seeking groups of 21 subjects each. Planned comparisons showed that, although both originality and fluency were related to stimulation-seeking in the predicted curvilinear form, only where fluency was concerned was a significant difference noted. Intermediate stimulation-seeking subjects were significantly more fluent than subjects low in stimulation-seeking although the former were not significantly different from high stimulation-seeking subjects. It was concluded that the experimental hypothesis had received limited support; further avenues to the study of arousal and stimulation-seeking factors in creative performance were outlined.


Let $A=\mathbb{F}_q[T]$ be the ring of polynomials in $T$ with coefficients in a finite field with $q$ elements. Let $\mathfrak{p}\lhd A$ be a maximal ideal, and denote $|\mathfrak{p}|=\# A/\mathfrak{p}$. Let $Y_0^r(\mathfrak{p})$ be the modular variety parametrizing Drinfeld modules of rank $r\geq 2$ over $A$ of generic characteristic with a $\mathfrak{p}$-cyclic subgroup level structure. Let $X_0^r(\mathfrak{p})$ be the Satake compactification of $Y_0^r(\mathfrak{p})$. We show that the cuspidal divisor subgroup of the Picard scheme of $X_0^r(\mathfrak{p})$ is a finite cyclic group of order $$\frac{|\mathfrak{p}|^{r-1}-1}{\gcd(|\mathfrak{p}|^{r-1}-1, q^r-1)}.$$ This is an analogue of a result of Ogg for classical modular curves $X_0(p)$ of prime level. We further define an Eisenstein ideal in the Hecke algebra acting on the Picard scheme of $X_0^r(\mathfrak{p})$, and show that the Eisenstein ideal has finite index in the Hecke algebra divisible by the order of the cuspidal divisor group.


Love is one of the most moving feelings and one of the eternal topics in world literature. The philosophic background of its charm is that it conquers man' s fear of death. This is reflected in Pushkin' s poetry of love. His early poems lay emphasis on sensual satisfaction, which is a reflection of his passion and self - consciouseness. And his late poems focus on intellectual agreement, which is a completion of individual transcedence and salvation in pursuit of "eternal female" , universal spirit.


Biochemical data analysis methods and systems are provided. You can receive a data set, the selection of comparison fields can be used to create a sub-group of data to perform statistical analysis. Subgroups of data set may be created based on the selection of the comparison field. Statistics for the data of each subgroup is calculated and displayed on the user's display. Other information, the user can provide a further improvement of the data set may provide a selection of the control group, and, by such selection, display of the population showing the control group is indicated It will be. The user may provide filtering of information of further data sets. Such information, before creating the sub-group for statistical analysis can be used to filter the data. .The


Simvastatin and atorvastatin are metabolized by the CYP3A4 enzyme and transported by the ABCB1 transporter. We studied whether the polymorphism CYP3A4*1B and the polymorphisms C1236T, G2677A/T and C3435T in the ABCB1 gene were associated with a decrease of the prescribed dose or a switch to another cholesterol lowering drug during simvastatin and atorvastatin therapy. These events may indicate that statin plasma levels were too high and resulted in an adverse drug reaction or a too strong reduction in cholesterol level.


Three different configurations of fold and flip bifurcation curves of maps, centered round a cusp point of a fold curve, are considered. They are called saddle area, spring area and crossroad area. For one and two-dimensional maps, this paper uses the notion of contour lines in a parameter plane. A given contour line is related to a constant value of a "reduced multiplier" constructed from the trace and the Jacobian of the matrix associated with a given periodic point. The singularities of such lines define the configuration type of the areas indicated above. When a third parameter varies, the qualitative changes of such areas are directly identified. These singularities also enable the determination of a point of intersection of two bifurcation curves of the same nature (flip or fold), and, when a third parameter varies, the appearance (or disappearance) of a closed fold or flip bifurcation curve.


Attitudes toward, and use of, money affects relationships, family stability, and even employment success. Recently, the effect of these issues on college students has been investigated. Eighty percent of undergraduates have credit cards with an average balance of $2,226 and 10 percent have outstanding balances of more than $7,000 (Kendrick as cited in Henry, Weber & Yarbrough, 2001). A survey by VISA found 8.7 percent of those filing for bankruptcy were below twenty-five years old (McBride as cited in Jones & Roberts, 2001). Financial management capabilities are essential to students' personal success and their academic success. Students able to manage their finances are more likely to organize their lives and manage their time in a way conducive to good academic progress (Weaver, 1992). At Idaho State University, lack of financial management is a reason students do not graduate (Eskelson, 2005). This study will evaluate the financial attitudes and perceptions, as well as the spending habits, of university freshmen. Implications are far-reaching and will provide valuable data for university administrators in enrollment management and student affairs, high school counselors, economic educators, and parents. Assisting students with information and strategies to improve their academic success and degree completion is vital.


Some aspects of the development of legal culture of the population of municipal formations in Russia are considered. The paper is dedicated to certain issues of the work of self-government bodies in the field of legal culture development in the second half of the 19th century, in the Soviet period and today. The general level of legal culture in municipal formations is compared for these historical periods. A justification for the conclusion that legal culture in municipal formations depends on the level of development of democratic procedures in forming self-government bodies is presented. The general state of legal culture in municipal formations is evaluated from the standpoint of citizens' trust to municipal authorities. The degree of such trust is regarded as dependent on the democratic nature of forming these authorities and their further work on improving their own operation.


The new combination Tradescantia boliviana (Hasskarl) J. R. Grant is made in recognition that it is a distinct species widespread in Peru, Bolivia, Paraguay, and Argentina, here separated by morphological characters and distribution from its previous inclusion within T. ambigua Martius ex J. H. Schultes, which is restricted to northeastern Brazil.


In this paper, the direct reduction of iron ore (DRI) with the lignite solid char in vertical furnace were investigated on different conditions, such as reduction temperature, residence time, ratio of solid char to iron ore. It is found that, at the range of 800~950°C, the degree of total iron (Fe%) and metallization (M%) increased with the temperature increasing, relatively, when the temperature rise up to 1100°C, Fe% was almost consistent, while M% decreased obviously. Fe% and M% increased with the residence time ranging from 0.25h to 1.5h, when it came up to 2h, both Fe% and M% varied merely. The influence of char consumption ratio on Fe% and M% had the same tendency with the residence time. When the ore size increased from 1~2mm to 5~6mm, Fe% was little change, and M% decreased with ore size increased. Finally, with grinding magnetic of the direct reduction, Fe% increased more than 5%.


ABSTRACT Language is commonly positioned as an economic resource. Recent debates have argued that policy interpretations of language as economic resource can potentially undermine language positioning and reduce understanding of the cognitive, cultural and social benefits of language learning. In monolingual policy contexts, such a positioning means that only specific languages of immediate economic value are embraced in policy. It also means the broader educational and intercultural long-term benefits of language learning are overlooked. Economic framing also means that language teachers must continually justify the importance of their work and prove the success of their programmes. Failure is often attributed to individual learner factors rather than acknowledging wider societal and programme impacts upon learning success. This paper reports on the factors teachers have identified as essential for success as they endeavour to implement languages programmes (or courses) within challenging policy settings in two English-speaking countries. A range of programme factors emerge as essential for long-term implementation within English-speaking contexts. Above all is the need for executive staff to lead the wider school valuing of languages education for its broader benefits. For language success to move beyond isolated school contexts, policy mandates are needed to ensure more time-on-task for languages in English-speaking countries. This in turn may begin a shift towards public valuing of language learning for broader educational and intercultural benefit.


Metal–insulator–semiconductor (MIS) field effect transistors were fabricated on InP substrates using a planar self‐aligned gate process. A 700–1000 A gate insulator of SiO2 doped with phosphorus was deposited by a direct plasma enhanced chemical vapor deposition at 400 mTorr, 275 °C, 5 W, and power density of 8.5 mW/cm2. High frequency capacitance–voltage measurements were taken on MIS capacitors which have been subjected to a 700 °C anneal and an interface state density of 1×1011/eV cm2 was found. Current–voltage measurements of the capacitors show a breakdown voltage of 107 V/cm and a insulator resistivity of 1014 Ω cm. Transistors were fabricated on semi‐insulating InP using a standard planar self‐aligned gate process in which the gate insulator was subjected to an ion implantation activation anneal of 700 °C. MIS field effect transistors gave a maximum extrinsic transconductance of 23 mS/mm for a gate length of 3 μm. The drain current drift saturated at 87.5% of the initial current, while reaching to ...


Abstract The processes involved in the induction and termination of facultative larval diapause in the parasitoid Colpoclypeus florus (Walker) was investigated in the laboratory. Larval diapause in C. florus is under maternal control. Photoperiod is the major factor governing the induction of larval diapause in C. florus. The pupa of the maternal generation is the most sensitive stage though the adult is also sensitive. Adult sensitivity increases with age, in particular at low temperatures. Photoperiod has no effect on the developing larva. The critical photoperiod for diapause induction for parasitoids maintained throughout the life cycle at 15 and 20°C was found to be 15 and 13.5 h, respectively. No diapause was induced at 25°C at any photoperiod examined. A chilling period of >5 wk is a prerequisite for diapause termination. After 8 wk at 5°C, all diapausing larvae pupate within 20 d whether held under short or long daylength. Chilling temperature and duration of chilling significantly affected diapause termination. Diapause development proceeds rapidly as chilling period increases and temperature decreases. The role of diapause in the biology of this parasitoid is discussed.


This paper discusses the annotation of resources with heterogeneous metadata and presents an information model as well as a reference implementation and showcases depicting how the model can be applied in real world situations. The presented approach provides resource and metadata management that allows for describing relations between metadata graphs, keeping track of provenance and access control. After presenting the model and the argumentation behind, the paper also describes the architecture of an implementation of the model and a web-based application taking advantage of it. It allows for describing re- sources with metadata, extending already existing metadata and harvesting of metadata repositories using different protocols, and exposes all metadata according to Linked Data principles. To show the taken approach in practice, several real-world examples are presented as showcases in the context of educational metadata and learning repositories.


Patterns of sustainable development have varied dramatically in the last five decades in China with a growing relevance of investments in 'eco-cities' being embedded within this discourse by politi...


Despite an established link between depression and higher Alzheimer's disease (AD) risk, it is unclear whether the conditions share pathophysiology. Here, we investigated whether depression manifesting after age 50 is associated with a genetic predisposition to AD.


Used cooking oil consumption causes cancer and the waste can pollute the environment. For that cases we need to find technology to change the oil become something useful like soap. The research aims to know the procedure to make soap from used cooking oil and Camellia sinensis extract and towards the growth of bacteria Staphylococcus aureus . There are two steps to purify the oil, purify with active carbon and banana peel. It was indicated by the formation of inhibition zones with the diameter occurred Cammelia sinensis extract with the size 12,5 mm, while the used cooking oil soap Cammelia sinensis extract 11 mm, alcohol 70% 5 mm, and tetrasiklin disc 15,8 mm. The conclusion are used cooking oil Cammelia sinensis extract can be modified into soap and soap from used cooking oil Camellia sinensis extract inhibited the growth of bacteria Staphylococcus aureus.


The renormalization-group recursion relations are solved for the effective Hamiltonians relative to phase transitions with four-component order parameters. For this value of n there are 22 types of Hamiltonians which can be classified into two categories according to the action of their normalizer Gz on the corresponding parameter space (Gz is the symmetry group leaving globally invariant this space). In the first case, G~ generates a finite number of isolated fixed points whose characteristics can be deduced from the detailed investigation of five Hamiltonians only. In the second category, for which G~ is a continuous group, there are, in addition to isolated fixed points, continuous manifolds of physically equivalent fixed points (the dimension of the manifolds is either one or three). In the search for a stable fixed point, the continuous manifolds can be ignored, while the isolated points are related to the five former Hamiltonians. For n =4, it is necessary to solve the recursion relations to two-loop order. The only possible stable ones among the fixed points then arise from a splitting of points which coincide, to one-loop order, with the isotropic fixed point. Extending, to twoloop order, a result recently established to the preceding order, we show that if a stable fixed point exists, it is unique. For n =4, the stable fixed point has one of three possible symmetries: diicosahedral, hypercubic, or dicylindrical. Despite this anisotropy of the critical fluctuations, the exponents associated with any of the stable fixed points are identical to order e to the "isotropic" exponents corresponding to n =4. The cubic point is destabilized by any operator of symmetry lower than cubic. The dicylindrical one remains stable with respect to certain anisotropies of lower symmetry. We examine the available experimental data in light of the preceding theoretical results concerning the critical behavior and the thermodynamic order of the transitions. On the other hand, we establish two general symmetry conditions relative to the stable fixed points determined by the renormalization-group equations. The first one specifies group theoretically, for each value of n, the possible symmetries G; of the stable fixed points. The second one formulates a necessary condition for the occurrence of an anisotropic stable fixed point: The normalizer G~ of the considered parameter space must fulfill the condition G~L:G;* for one, at least, of the former G;* groups. These rules are shown to be very restrictive for n =4: On the basis of symmetry the lack of a stable fixed point can be asserted for 10 Hamiltonians out of 22, without solving the fixed-point equations.


Eggs, nymphs, and adults of both sexes of the triatomine Psammolestes arthuri together with its scelionid parasite, Telenomus capito , were found in nests of the Plain-fronted Thornbird, Phacellodomus rufifrons inornatus , in El Porvenir the Colombian oriental plains. This is the 1st record of these insects outside Venezuela. Only the outer eggs of P. arthuri egg masses were parasitized (54% of all the outer eggs and 35% of the total number of eggs). This pattern is presumably not due to the cementing material between eggs, but rather to the position of the eggs themselves. The frequency of parasitism of the egg masses laid on the external, looser portion of the bird nest was significantly higher than that found for the egg masses laid closer to the central, denser part of the nest.


Pancreatic islets are composed of different hormone‐secreting cell types. A finely balanced combination of endocrine cells in the islets regulates intraportal vein secretions and plasma nutrient levels. Every islet cell type is distinguished by its specific secretory granule pattern and hormone content, endocrine and cell signaling mechanisms, and neuronal interactions. The scarcity of pancreatic islet donors for patients with diabetes has caused a considerable interest in the field of islet xenotransplantation. Previous studies have shown that cell arrangement in the pancreatic islets of ruminants differs from that of other mammals; however, caprine islet cytoarchitecture has not yet been comprehensively described. This investigation aimed to characterize caprine islets in regard to better understanding of caprine islet structure and compare with previously reported species, by conducting a detailed analysis of islet architecture and composition using confocal microscopy and immunofluorescence staining for pancreatic islet hormones.


High-speed railways have a high demand for safety, but they are complex systems when it comes to fault diagnosis. The failure propagation path is difficult to trace which makes it hard to detect and identify a fault in the traditional way like signal-based methods. In recent years, artificial intelligence methods have been successfully applied in system health diagnosis and prognosis. Fault diagnosis methods based on artificial intelligence methods provide a new inspiration for fault diagnosis in the high-speed railway systems. In this article, the current research status of fault diagnosis was introduced, and the practical application of fault diagnosis methods in high-speed railways was summarized. Then taking the train control system as an example, fault diagnosis based on the artificial intelligence methods was discussed using several case studies; the results proved that the fusion of different methods has the potential to improve the diagnostic accuracy. Finally, the future research direction of fault diagnosis for high-speed railways was proposed.


In order to study the deformation behaviors of expressway embankment over soft ground during the whole widening process,numerical models of newly built narrow embankment,newly built wide embankment and widened embankment were established based on the finite element numerical simulation. The developments of ground surface settlement,embankment surface settlement and ground lateral displacement of each model were compared and analyzed. The results show that widened embankment 's deformation behaviors are much more complicated than those of newly built embankment,and the settlement curve of widened embankment will change from W- type,to U- type,then to W- type. The ground under the old embankment toe lateral displacement moves to the side of old embankment,and then to the side of new embankment and later retracts. The interaction between old and new embankment should be taken seriously. Not only the post- construction settlement should be controlled,but also the settlement and differential settlement of old embankment during the new embankment construction should be focused on. These conclusions will be benefit in the determination of the settlement control index system and soft ground treatment measures.


We present an approach to the problem of light propagation in turbid media based on the diffusion equation. The most favorable path over which photons can be found can be obtained from the path of the net flux propagation. The diffuse intensity and the direction of the net flux flow can be calculated with the finite element method, which can deal with heterogeneous problems and frequency domain problems within complex geometry, and can introduce boundary effects as well. Simulations were conducted for phantoms with different parameters and source-detector separations. Experiments have been performed to verify this new method.


A new type of single crystals of trigonal polyoxymethylene was found in a cationic polymerization system of trioxane desigened to grow needle-like polyoxymethylene single crystals (polymer whisker). A number of small particles of polyoxymethylene (Figure 2) were observed on the thin film of t-POM formed over the inner wall of the reaction vessel. The particle samples were comprising a lots of small rod-like transparent crystalline units packed at random. It has been clarified that the particles consist of the trigonal crystalline form of polyoxymethylene, moreover these rod-like single crystals consist of the extended chain structures from the infrared spectra.


The IACP Research Advisory Committee is proud to offer the monthly Research in Brief column. This column features evidence-based research summaries that highlight actionable recommendations for Police Chief magazine readers to consider within their own agencies. The goal of the column is to feature research that is innovative, credible, and relevant to a diverse law enforcement audience.


Copyright© 2021, the Authors | Publishing Rights, ASPI. This open-access article is published under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License which permits Share (copy and redistribute the material in any medium or format) and Adapt (remix, transform, and build upon the material) under the Attribution-NonCommercial terms. The Effect of Cognitive-Behavioral Intervention on SelfCare Behaviors and Blood Pressure Control in Patients with Primary Hypertension


We investigated the effects of matrix type and reagent batch changes on diagnostic performances and longitudinal trajectories of brain‐derived tau (BD‐tau).


The administration of cis-dichlorodiammineplatinum to rats at 10 days of postnatal life (PD 10) alters the immunoreactivity for parvalbumin of the interneurons of the cerebellar molecular layer at late post-treatment intervals. This can result in, but may be also a consequence of the elevation in the cytosolic calcium concentration. Changes in the intracellular calcium homeostasis may induce damage of the cytoskeletal apparatus and impair growth of the cell processes leading to alteration of the ultrastructure of the cell.


and professional reality of Educational Psychology, both as a science and as a professional field, degrees, masters and doctorates in Psychology stand at a significant crossroads. The complexity of this situation is due to a series of interacting factors, which can be summarized as follows: 1) The changes deriving from the process of convergence within the European Higher Education Area (Benítez, Berbén, Justicia, & De la Fuente, 2006; Lucas, 2007) provide a golden opportunity to reconsider, at least, and indeed to reformulate the way we view Psychological Science, as well as its contributions to the field of professional application. 2) The rapidly changing scene in the labour market and systems of production should lead us to at least reappraise the contribution of Educational Psychology to the scientific and technological system, as well its role in the current context of scientific and technological innovation. In the Knowledge-Based Society of the 21st century, in which Europe aims to position A r t i c l e s


Pictured on the cover are two diagrams of the layout of instruments at the NIST Center for Neutron Research spanning 40 years of activity. On the right in black and white is the layout in 1975 in which the instruments using thermal neutrons were clustered around the reactor. On the same scale, the colored diagram depicts the instrument layout as it is planned for 2015, with instruments using cold neutrons located on guides emanating from the cold source housed in the " thimble " included in the original reactor design. Most of these instruments are located in the original guide hall building to the left of the " dots " running down the middle of the lower portion. The dots are the columns of the original wall before the expansion guide hall (to the right) was constructed in 2010. has worked as a physicist at the NCNR since 1999. Among other activities, he edits the NCNR Accomplishments and Opportunities annual report. 2 DISCLAIMER Certain Commercial entities, equipment, or materials may be identified in this document in order to describe an experimental procedure or concept adequately. Such identification is not intended to imply recommendation or endorsement by the National Institute of Standards and Technology, nor is it intended to imply that the entities, materials, or equipment are necessarily the best available for the purpose.


Soft robotics has the potential to revolutionize robotic locomotion, in particular, soft robotic swimmers offer a minimally invasive and adaptive solution to explore and preserve our oceans. Unfortunately, current soft robotic swimmers are vastly inferior to evolved biological swimmers, especially in terms of controllability, efficiency, maneuverability, and longevity. Additionally, the tedious iterative fabrication and empirical testing required to design soft robots has hindered their optimization. In this work, we tackle this challenge by providing an efficient and straightforward pipeline for designing and fabricating soft robotic swimmers equipped with electrostatic actuation. We streamline the process to allow for rapid additive manufacturing, and show how a differentiable simulation can be used to match a simplified model to the real deformation of a robotic swimmer. We perform several experiments with the fabricated swimmer by varying the voltage and actuation frequency of the swimmer's antagonistic muscles. We show how the voltage and frequency vary the locomotion speed of the swimmer while moving in liquid oil and observe a clear optimum in forward swimming speed. The differentiable simulation model we propose has various downstream applications, such as control and shape optimization of the swimmer; optimization results can be directly mapped back to the real robot through our sim-to-real matching.


Background: Pulmonary hypertension (PH) is a deadly vascular disease with enigmatic molecular origins. Facets of PH have been characterized in isolation, but many have yet to be unified by a common upstream regulator. Methods & Results: We constructed a network in silico of 247 genes and 2,274 functional interactions involved in PH. Using this model and advanced network analysis, we predicted the miR-130/301 family to have the most diverse pool of PH-relevant target genes among conserved microRNAs (miRNAs). Guided by these predictions, we found that this family was up-regulated by hypoxia, inflammatory cytokines, and factors genetically linked to PH. MiR-130/301 family members were also up-regulated in remodeled pulmonary vessels in 7 animal models and 3 human subtypes of PH. Via gain- and loss-of-function experiments in vitro , we found that miR-130/301 suppressed a cohort of PPARgamma-related targets to regulate two pro-proliferative pathways (the apelin-miR-424/503-FGF2 axis in PAECs and the STAT3-miR-204-SRC axis in PASMCs); vasomotor tone ( e.g. , endothelin-1 and endothelial nitric oxide synthase); and extracellular matrix remodeling ( e.g. , the collagen crosslinking enzyme LOX). In turn, delivery of miR-130a mimic oligonucleotides in pulmonary vessels of mice altered expression of the predicted cohort of PPARgamma-related factors, leading to increased vascular remodeling (19.62±1.36 percent muscularized arterioles for miR-130a vs. 6.98±0.55 percent for scrambled control, p 3 *dyn*s*cm -5 ] for miR-130a vs. 462±25.4 for control, p in vivo via antisense oligonucleotides mitigated these effects. Conclusions: We used network modeling to identify miR-130/301 as a master regulator of PH and a novel potential therapeutic target. These findings provide critical support for the evolving application of network modeling to discover the hidden molecular origins of PH and other human diseases.


Background: Creative activities are easy to access leisure activities with potentially positive effect on health and wellbeing after stroke; however, there is limited research evidence about their ...


Backgroud: 2D thick slab single shot fast spin echo (SSFSE) sequence in MRCP examination is a sequence of fast spin echo (FSE) which has a long turbo factor so that the time of acquisition in this sequence is longer than usual that will potentially cause image blurring. Parallel acquisition or SENSE technique is a technique used to reduce acquisition time and improve spatial resolution. The purpose of this study was to determine differences in anatomical information with and without parallel acquisition technique in 2D thick slab SSFSE sequences on MRCP examination. Methods: This research was an experimental study. This research was conducted by Philips 1.5 T MRI unit in dr. S Hardjolukito Yogyakarta Hospital. Data were 20 MRCP images from 10 normal volunteers with and without parallel acquisition technique on sequences of 2D thick slab SSFSE. Assessment of the images was conducted qualitatively in the form of respondents's assessment of the clearance of anatomical information includes the gallbladder, right hepatic duct, left hepatic duct, common bile duct, common hepatic duct, cystic duct, and the main pancreatic duct. Quantitative data analyzed by Cohen's Kappa test, cross tabulation, and Wilcoxon tests. Results: The result showed that there was a difference between the clearance of the overall anatomical information between 2D thick slab SSFSE sequences with and without parallel acquisition technique in MRCP with p = 0.000 (p-value< 0.05), based on the mean rank obtained sequences of 2D thick slab SSFSE SENSE (14.50) better than the 2D thick slab SSFSE (0.00). Analysis of each anatomy showed significant differences in all organs except the gallbladder p = 0.059, p = left hepatic duct and the common bile duct 0.059 with p = 0.08. Conclusion: Parallel acquisition technique (SENSE) was well used because it has a faster acquisition time without decreasing image resolution.


In this subject, thermosonic flip-chip technology was introduced to conduct low-temperature bonding of Ag paste and chip interconnection experiments with micro solder joints. The coating and printing method is used to realize the uniform coating of the Ag paste on the micro Cu pillars, and the thickness of the coated Ag paste can be controlled. During flip-chip bonding, different power, pressure, temperature, and bonding time will affect the shear resistance of the solder joint after bonding. Therefore, this article controls the above factors and only studies the impact of ultrasonic power and pressure on the shear force of the solder joint interface. The experiment found that before reaching the maximum shear force, as the ultrasonic power increases, the shear resistance of the solder joint also gradually increased. After that, as the ultrasonic power increased, the shear resistance of the solder joints gradually decreased. It shows that when using thermosonic flip-chip technology for chip bonding, the ultrasonic power should be maintained in an appropriate range to make the bonded flip-chip solder joints obtain a maximum shear strength. The bonding pressure is proportional to the shear strength of the solder joint.


Reports of tick anaphylaxis are extremely rare in Asian countries, with poor awareness in these regions. Herein, we report a case of tick anaphylaxis that was triggered by pulling out the tick.


AIMS AND OBJECTIVES
To compare pressure ulcer incidence and costs associated with repositioning older individuals in long-term care using two different repositioning regimes.

BACKGROUND
Repositioning has not always been integrated into pressure ulcer preventative methods, with arguments that it is an expensive procedure in terms of personnel and time.

DESIGN
Participants were randomly allocated to the experimental group (n = 99; repositioned every 3 hours, using the 30° tilt) and the control group (n = 114 standard care, repositioned every 6 hours, using the 90° lateral rotation). The analysis explored the incidence of pressure ulcer development and the cost difference between the two repositioning schedules, over a 4-week period.

RESULTS
The mean daily nurse time for repositioning was 18·5 minutes (experimental) and 24·5 minutes (control). Nurse time cost per patient over the study period was €206·6 (experimental) and €253·1 (control), 96·6% of participants (experimental) remained free of pressure ulcers, compared with 88·1% (control). The cost per patient free of ulcer was €213·9 (experimental) and €287·3 (control). Projected annual costs were estimated for the 588 (53·5%) residents in the 12 study sites requiring repositioning. The cost would be €1·59 m (experimental) and €2·10 m (control), a cost difference of €510,000. This represents a difference of 58·8 hours of nurse time, equivalent to approximately 12 full time nurses across the 12 sites.

CONCLUSION
Repositioning every 3 hours, using 30° tilt, has been shown to be more effective in less costly in terms of nurse time compared with standard care.

RELEVANCE TO CLINICAL PRACTICE
Repositioning individuals at risk of pressure ulcer development makes both economic and clinical sense, thereby supporting the EPUAP/NPUAP 2009 guidelines.


other questions about how the Cultural Revolution unfolded throughout the province, and does not explain more sociological dynamics of the mass organizations and demonstrations, the rise of new leaders or the roles of workers and students. Such topics are more difficult to document, but are also important to the study of rebellion, popular protest and political restructuring. One hopes that the appearance of this reasoned political account will facilitate a similarly comprehensive and dispassionate examination of the social aspects of the turmoil.


The laser damage resistance of fused silica optics depends significantly on the surface quality. In this work, anisotropic etching with inert ion beams at various ion incident angles was performed ...


Liver cancer is the fifth most common cancer worldwide and the second
cause of cancer death with 600,000 cases each year. Cancer therapies that exist
until this day still has disadvantage, so it needs a specific drug to stop the cancer
cells . Isatin and its derivatives are known to have anti-cancer activity. Isatin has
cytotoxicity on leukemic cancer cells U937 with IC50 565 M. subtituent group at
C-3 isatin affect its bioactivity, convolutamidine A and convolutamidine B can
inhibite leukemic cancer cell HL-60 with IC50 0,1-25 and 12-25 g/mL
respectively. Subtituent group at C-5 in 5-nitroisatin also affect the bioactivity to
leukemic cancer cells U937 such as 5-nitroisatin with IC50 132 M. It is known to
have anti-cancer activity better than the isatin. Nitro groups can also decrease the
cytotoxicity as the 3-hydroxy-5-nitro-3-(1H-indole-3-yl)indoline-2-one that have
IC50 195 M to colon cancer cells WiDr, while the 3-hydroxy-3-(1H-indole-3-
yl)indoline-2-one have IC50 37 M. 11-nitro-6-demetoksiakronisina has activity
against leukemia cancer cells L1210 better than the 11-amino-6-
demethoxyacronisina, whereas compounds with aromatic amine group, 1-amino-
8,9-dimethoxy-5-[2-(N,N-dimethylamino)-ethyl]-5Hdibenzo[
c,h][1,6]napthyridin-6-one has better activity to leukemia cancer cell
RPMI 8402 than aromatic nitro group, 8,9-dimethoxy-1-nitro-5-[2-(N,Ndimethylamino)-
ethyl]-5H-dibenzo[c,h][1,6]napthyridin-6one. N-methyl at isatin
also affect bioactivity, for example N-methylisatin (IC50 238 μM) is more
potential than isatin (IC50565 μM) as anti-cancer, but (E)-methyl 3-(N-methyl-
2,3-dioxoindolin-5yl)acrylate has worse bioactivity than (E)-methyl 3-(2,3-
dioxoindolin-5yl)acrylate with IC50 0,340,09 and 0,220,09 M respectively.
Research has been done succefully synthesize novel isatin derivatives; 3-hydroxy-
3-(1H-pyrrol-2-yl)indolin-2-one, 3-hydroxy-5-nitro-3-(1H-pyrrol-2-yl)indolin-2-
one, 3-hydroxy-N-methyl-5-nitro -3-(1H-pyrrol-2-yl)indolin-2-one, and 5-amino-
3- hydroxy-3-(1H-pyrro-2-yl)indolin- 2-one obtained with yield 47, 50, 63 and 47
% respectively. Cytotoxicity test found that 3-hydroxy-5-nitro-3-(1H-pyrrol-2-
yl)indolin-2-one citotoxic to liver cancer cell HepG2 with IC50 468 μM, whereas
3-hydroxy-3-(1H-pyrrol-2-yl)indolin-2-one, 3-hydroxy-N-methyl-5-nitro -3-(1Hpyrrol-
2-yl)indolin-2-one, and 5-amino-3- hydroxy-3-(1H-pyrro-2-yl)indolin- 2-
one less cytotoxic with IC50 10332, 1330 and 4636 μM respectively. Nitro and
amino group substituen at C-5 unit isatin can enhance the cytotoxicity, whereas
the presence of N-methyl group can lower cytotoxicity to liver cancer cells
HepG2.


. . . for a black person, history is a challenge because a black person is supposed not to have any history except the colonial one. We hardly know what happened to our people before the time when they met the Europeans who decided to give them what they call civilization. For a black person . . . from the diaspora . . . it is a . . . challenge to find out exactly what was there before. It is not history for the sake of history. It is searching for one's self, searching for one's identity, searching for one's origin in order to understand oneself. (Maryse Conde) The figure of the African American historian in David Bradley's The Chaneysville Incident is almost the antithesis of the historian Hayden White delineates in "The Burden of History," a person who needs to be liberated from the burden of history. The African American historian, Bradley would argue, needs to take on and reconfigure that burden, but not by having recourse, as White suggests, to developments in Western culture, to literary modernism or even post-modernism. Bradley's historian, John Washington, goes outside the Western tradition and taps into the residue of African beliefs in African American culture (much as Paule Marshall's Avey Johnson does in Praise song for the Widow) to create an alternative and heroic history. Washington's powerful narrative of the death of his forebear, C.K., and a group of escaped slaves is only made possible by history, and his groundwork as an historian bears much the same relation to his fiction as does Toni Morrison's relation to her research and her fiction Beloved. The ground of history and the work of the historian make possible fiction that fills in the historical gaps, but this effort, for the African American community, as the novel demonstrates, has more than an archival gravity. Historical consciousness, leavened by the imagination, allows us all, no matter what our experience and ethnicity, to know where we all stand in the present. Hayden White, by contrast, has argued that in order for us to know where we stand in the present the "historical consciousness must be obliterated," particularly "if the writer is to examine with proper seriousness those strata of human experience which it is modern art's peculiar purpose to disclose." Using the figure of the "historian to represent the extreme example of repressed sensibility in the novel," novelists, White claims, have indicted historians either "for a failure of sensibility or will," and as a result, "the [fictional] historian's claim to be an artist appears to be pathetic when it does not appear merely ludicrous" ("Burden" 31). Historians, both in and out of fiction, White contends, are seen as having no wisdom appropriate to the unique conditions of this century, and "contemporary Western man . . . is justifiably convinced that the historical record as presently provided offers little help in the quest for adequate solutions" to contemporary problems. White then pushes his analysis one step further, arguing that artists have come to believe that" 'the historical imagination' . . . constitutes the fundamental barrier to any attempt by men in the present to close realistically with their most pressing spiritual problems" ("Burden" 39; emphasis added). White finds these assumptions at work in depictions of the figure of the historian in imaginative literature, but the writers that he alludes to in support of this contention are all male and, with the exception of Edward Albee, all European. Using terms like "contemporary Western man" ("Burden" 41), White is concerned with traditional history and with canonized male writers of fiction. I would like to decenter his analysis of the historian in fiction by looking at an African American writer, David Bradley, and his African American historian John Washington from The Chaneysville Incident. If the figure of the white historian throughout this century is to be seen as a symptom of a large cultural failure in the "West," is the figure of an African American historian to be viewed any less pessimistically? …


The group of questions which are connected with the Glacial Age seem to me to be among the most interesting and the most difficult in the whole science of geology. They include the question of Time—since, perhaps, the only hope we have of even reaching any unit of time in geological changes lies in the phenomena of the Glacial Age, The question of the comparative slowness or suddenness of great physical changes is not less directly involved. Bound up with this again is the question of the sudden or slow destruction of the extinct forms of life, and the introduction of new forms to replace them. The connection between Cosmical and Terrestrial causes of change comes directly into our view, and then the nature and operation of the terrestrial forces which were brought into play. I am very sceptical as to many of the solutions which have been proposed for most of these questions, and still more for the theories which profess to answer them as a whole. There is nothing to be done but to accumulate evidence in detail—to observe facts well, that is, completely—and avoid looking only at such of them as tell in favour of some preconceived hypothesis.


BACKGROUND
Treatment for metastatic breast cancer (MBC) in patients who have relapsed from anthracycline and taxane is difficult. S-1, an oral 5-FU derivative, has demonstrated a potential antitumor effect in patients with MBC. Thus, we evaluated the efficacy and safety of S-1 as second-line chemotherapy MBC patients in a phase II trial.

METHODS
The study was conducted at seven centers in China and enrolled MBC patients who had previously relapsed from one chemotherapy regimen. The median progression-free survival (PFS) was the primary end point. The treatment schedule involved the administration of S-1 at a standard dose based on the body surface area (BSA) in 28-day cycles with consecutive administration followed by a 14-day rest, as follows: 40 mg twice daily if BSA < 1.25 m(2); 50 mg twice daily if 1.25 m(2) ≤ BSA ≥ 1.5 m(2); and 60 mg twice daily if BSA > 1.5 m(2).

RESULTS
Thirty-three patients were included in the analysis. S-1 demonstrated moderate efficacy with a PFS of 3.3 months, a response rate of 33.3%, and a disease control rate of 72.7%. The treatment was well-tolerated with mild-to-moderate toxicity. Grade 3 adverse events (AEs) occurred in 4 patients (2 with hyperbilirubinemia, 1 with anorexia, and 1 with vomiting). Grade 4 AEs were not observed.

CONCLUSION
S-1 demonstrated encouraging efficacy and safety in a prospective trial as second-line treatment in MBC patients. All AEs were manageable; however, bilirubin monitoring is recommended during treatment.


The Language Centre at Sultan Qaboos University is the academic unit that is responsible for teaching English. However, teaching English is only one of the three functions that it has. The other two functions are carrying out different types of language assessments and conducting research in the field of language instruction and acquisition. Underpinning the third function, which is conducting research, is the rationale that it is through research that educational institutions can come to an understanding of the various phenomena or situations that could emerge in language teaching contexts, and the factors that shape them. Based on this understanding, it is believed that it "will have a beneficial effect on language teaching and learning" (Borg, 2009, p. 1). The purpose of this paper is to report on the main findings and implications of a study that aimed at exploring the perceptions of the Language Centre teachers on research, its advantages and constraints, as well as their ideas regarding the ways in which ELT research and research culture can be promoted at their institution.


Constructing virtual training system based on Virtools technology is useful for enhancing the efficiency and effect of training. In this paper, we analyze the intension of virtual training system, expatiate the meaning of virtual training system in oil jobs training, generalize the technical characters and advantages of Virtools, and take the example of installing BOP to introduce the design of virtual training system.


Digital Soil Mapping (DSM) is the computer-assisted production of digital maps of soil type and soil properties. It typically implies use of mathematical and statistical models that combine information from soil observations with information contained in correlated environmental variables and remote sensing images . Accurate estimation of soil organic carbon (SOC) variability could provide critical information for understanding nutrients cycling and sediment. In this study, Artificial Neural Networks (ANNs) were developed to estimate SOC variability based on topographic indicators (terrain attributes) and remotely sensed data. SOC values for 85 surface soil samples were measured and corresponding attributes were obtained from the digital elevation model (DEM) with an accuracy of 10 meters. In addition, the Landsat 7 image acquired on August 2002 was used. This image consists of six bands: B1 (0.45-0.52 μm), B2 (0.52-0.60 μm), B3 (0.63-0.69 μm), B4 (0.76-0.90 μm), B5 (1.55-1.75 μm) and B7 (2.08-2.35 μm). T he data points were divided by randomization technique and 80% data was selected to train the model and remaining 20% was used to test the model. The root mean square error (RMSE) and coefficient of determination were used as evaluation criteria, respectively. Although there is a significant correlation between SOC and terrain attributes and can be used to estimate SOC, due to carbon dynamics in soil, this point should be considered that other factors also control the amount and distribution of SOC , Therefore, we can not expect that all changes can be predicted by this approach . Normal 0 false false false EN-US X-NONE AR-SA /* Style Definitions */
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The article is dedicated to the teaching methodology of using the system of the means o f the folk art in fanning art culture of the students. The ways of the intensification of the teaching and upbringing process of the readiness of the teachers-to be o f Handicraft during studying o f the disciplines o f Art are led to made conditional


The main objective of this study was to examine the effects of addition of L-cysteine in diluents on the qualitative parameters and peroxidation level of membrane lipid of frozen-thawed sperm.The results show that:(1)Addition of 0.1 mg·mL-1 L-cysteine in diluents can significantly improve the viability,the rate of acrosomal integrity and in vitro fertilization rate of frozen-thawed sperm(P0.05),but does not affect the kinematic parameters(P0.05).(2)Addition of L-cysteine(0.1,0.2 and 0.3 mg·mL-1 L-cysteine) in diluents can significantly reduce the level of membrane lipid peroxidation(P0.05).Our results show that addition of L-cysteine in diluents can improve the efficiency of pig sperm cryopreservation.


Abstract This study compared catches of Panulirus argus pueruli and very young juveniles between Hunt and Sandwich collectors at Long and Big Munson Keys, Florida, United States. Catch comparisons were made over the peak puerulus settlement period between February and July 2002, using six Sandwich and six Hunt collectors at each site. The collectors were set out in arrays and the relative positions of the two collector types were reversed each month after they had been checked and the catch removed. A total of 3470 pueruli and juveniles were collected; 2011 and 1459 by Sandwich and Hunt collectors, respectively. Sandwich collectors caught an average of 5.43 more pueruli and juveniles per check than Hunt collectors, with this difference being significant for catches of clear pueruli (P1s), pigmented pueruli (P3s), and juvenile stages (J1s and J2s) (P < 0.05), but not for catches of semi‐pigmented pueruli (P2s). The catches made by both collector types were highly dependant on the month of collection and site of the collectors (P < 0.01). Catches were generally not influenced by the location of the collector in the array (P = 0.50), but corner collectors caught significantly fewer P1s, P2s, P3s, and J1s and J2s than all other collectors (P < 0.01). Conditioning time influenced the total catch (P < 0.01) but was not significant for all individual P1s, P2s, P3s, and J1s and J2s stages of development. Overall, the time taken for collectors to condition in Florida was less than the Sandwich collectors used for P. cygnus in Western Australia.


ABSTRACT Park-and-ride facilities are parking lots located on the periphery of cities to intercept car trips coming from the suburbs and diverting them to a transit system, thus playing a potentially important role in reducing traffic congestion and air pollution in urban areas. In this paper, we present a study carried out to shed light on where to install park-and-ride facilities in the city of Coimbra, central Portugal. Its main component is an optimization model which aims to determine the best possible locations for a given number of park-and-ride facilities under the objective of minimizing car use in the urban areas. The main result of the study is that the introduction of only three park-and-ride facilities could reduce car use in Coimbra's urban areas by 19%, an impact that would be very difficult to achieve through measures such as decreasing bus fares, increasing parking fees and/or increasing bus services.


Under the assumption that one has a reference device identical or similar to the target device, and thus be well capable of characterizing power leakages of the target device, template attacks are widely accepted to be the most powerful side-channel attacks. However, the question of whether template attacks are really optimal in terms of the leakage exploitation rate is still unclear. In this paper, we present a negative answer to this crucial question by introducing a normalization process into classical template attacks. Specifically, our contributions are two-fold. On the theoretical side, we prove that normalized template attacks are better in terms of the leakage exploitation rate than classical template attacks; on the practical side, we evaluate the key-recovery efficiency of normalized template attacks, classical template attacks, and PCA-based template attacks. Evaluation results show that, compared with both classical template attacks and PCA-based template attacks, normalized template attacks are more effective. We note that, the normalization process does not depend on any special conditions and the computational price of the normalization process is of extremely low, and thus, it is very easy-to-implement in practice. Therefore, the normalization process should be integrated into classical template attacks as a necessary step, so that one can better understand practical threats of this kind of side-channel attacks. Copyright © 2016 John Wiley & Sons, Ltd.


This paper briefly analyzes the advantages for Fujian Sanming Chemical Industry Co.,Ltd developing methanol product.After comparing processes with different feeds,the author makes a calculation on material balance in the process of methanol production with coking gas and converter gas as feed,discusses the economic benefits,and proves that the process is totally suitable for Fujian Sanming Chemical Industry Co.,Ltd.


Microstructure of high coercive pulsed laser deposition (PLD) made Nd-Fe-B thick-film magnet improved by "Tb-coating-diffusion" treatment has been investigated with an analytical transmission electron microscope (ATEM). It was found that the PLD-made film consists mainly of fine Nd 2 Fe 14 B grains about 200 nm in diameter and a large amount of Nd intergranular phases. Energy dispersive X-ray spectroscopy (EDS) analysis showed that each Nd 2 Fe 14 B grain is covered with a thin (Nd,Tb) 2 Fe 14 B layer about 20-30 nm in thickness and thin Nd-Tb grain-boundary-layer about 5-10 nm in width. The present results indicate that such a two-layered-wrapping structure enhances significantly the coercivity of the PLD-made thick-film magnet.


With advancements in technology, the use of Virtual Reality (VR) and Artificial Intelligence (AI) in the hospitality industry has become common. New technologies have changed the guests expectations and their journey. Therefore, the purpose of this paper is to provide a comprehensive conceptualization of the personalized guest experience journey in leisure hotel i.e. the way front-line employees creates personalized and pro-active guest experience that the intelligent use of data and technology support. The paper provides systematic literature review of VR and AI as support tool for front-line employees while creating personalized guest experience during each of the five stages of the guest cycle: prearrival, arrival, stay, departure, post-stay. This paper is theoretical, so empirical studies are necessary to validate or reject the proposed concept.


The subject innovation is uniform and related to highly efficient filtration and has a bottom-up as well as one to efficiently remove the suspended matter generated in the water treatment process so as to enable the filter medium to semi-removable membrane filtering device. In the subject innovation, and intermittent control by influent automatic control valve, from the bottom five. It controlled by the inflow pipe and outflow automatic control valve for supplying the waste water, and having the effluent pipe installed above to discharge the purified water and, inside filtering water tank and forming a space, a pressure gauge and a pressure switch provided on the upper end of the space portion; The filter member and so as to separate the interior of the filtering water tank into an upper and a lower space, is installed at least one O in the central portion thereof so as to filter the waste water and; The filter member to consist of back washing means is automatically actuated by a pressure switch which operates according to the signal of the pressure gauge detects the clogging degree of the filter member is installed in a cylindrical shape or cap shape of a square pillar-like in order to maximize the filtering cross-section filter screen and that; Perforated cores which are provided on the outside of the filter screen filter to support the filter screen during operation and; Consists of a ring spring, which is installed on the inside of the filter screen so as to support them, and the backwashing means being controlled by the back washing automatic control valve A, supplies a reverse revenue upwardly space (A) of the trapping filter member installed in the water tank wash station to the supply pipe; Backwash nozzle which is controlled by the automatic backwash valve B, is installed in the lower space (B) of the trapping filter member provided inside the tank so as to spray the foam by mixing air with wash station and; An air supply pipe and the wash station to the backwash air supply nozzle to mix with; Characterized by configured to branch pipes for distributing supplying each station in the wash station wash supply line and the backwash nozzle.


ABSTRACT In recent years, radical and violent Islamist movements – such as al-Qaeda and its offshoot the Islamic State in Iraq and Syria – have seized the spotlight. A corollary of this preoccupation has been the proliferation of studies on the political thought of radical Islamist figures such as Abu Muhammad al-Maqdisi, Ayman al-Zawahiri and Osama bin-Laden. By contrast, scant attention has been paid to the thought of moderate contemporary Sunni Islamist scholars. This article attempts to rectify this situation by focusing on the international relations discourse of a prominent Syrian Islamist thinker Sheikh Wahbah al-Zuhaili (hereafter Zuhaili). The article examines Zuhaili's views on three central and interrelated topics: (1) the nature and underpinning principles of international relations; (2) war; and (3) the role of international law and international norms and conventions in international relations. By shedding light on Zuhaili's thought and situating it in its proper ideational and historical contexts, the article concludes that radical Islamist ideology is at the periphery of contemporary Islamist conceptualizations of international relations while the epicentre is held by mainstream Islamists whose perspectives on international relations are fairly compatible with prevalent western views, especially those emanating from the Realist school.


 Of the 1.35 million people who die each year as a result of road traffic crashes, more than half are among vulnerable road users: pedestrians, cyclists, and motorcyclists.  Road traffic injuries are the leading cause of death for children and young adults aged 5-29 years.  About three quarters (73%) of all road traffic deaths occur among young males under the age of 25 years.  93% of the world's fatalities on the roads occur in lowand middle-income countries, even though these countries have only 60% of the world's vehicles.  Between 20 and 50 million more people suffer non-fatal injuries, with many incurring a disability as a result of their injury.


ABSTRACT Commonly used "inactive" pharmaceutical excipients were tested in a previously developed minimum cidal concentration assay to assess their ability to kill Chlamydia trachomatis topically. Sixteen excipients were evaluated in these studies under various conditions. A range of activities was found among the excipients that could be tested in our assay system.